BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P54970 (439 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1XMB-A nrPDB 860 0.0 3IO1-A nrPDB 101 5e-22 4O23-A nrPDB 48 1e-05 1CG2-A nrPDB 38 0.008 3RZA-A nrPDB 33 0.19 2AP1-A nrPDB 32 0.49 3CT9-A nrPDB 31 0.87 5C5I-A nrPDB 30 1.6 4PU3-A nrPDB 30 2.7 1BZS-A nrPDB 29 3.6 2RB7-A nrPDB 29 5.0 5JLC-A nrPDB 28 6.4 >1XMB-A nrPDB Length = 418 Score = 860 bits (2223), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/418 (100%), Positives = 418/418 (100%) Query: 22 SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELEL 81 SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELEL Sbjct: 1 SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELEL 60 Query: 82 IGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDG 141 IGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDG Sbjct: 61 IGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDG 120 Query: 142 HVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSAR 201 HVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSAR Sbjct: 121 HVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSAR 180 Query: 202 IPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETD 261 IPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETD Sbjct: 181 IPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETD 240 Query: 262 PLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS 321 PLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS Sbjct: 241 PLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS 300 Query: 322 VNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHF 381 VNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHF Sbjct: 301 VNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHF 360 Query: 382 SLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL 439 SLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL Sbjct: 361 SLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL 418 >3IO1-A nrPDB Length = 445 Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 75/244 (30%), Positives = 113/244 (46%), Gaps = 21/244 (8%) Query: 9 LTFQLLLFLLSVS-SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKI-------RRKIHE 60 ++ QL +L ++ S + W + ++ LEF + +V D + + R I Sbjct: 1 MSLQLDEYLRQLAPSMTQWRRDFHLHAESGWLEFRTASKVADILDGLGYQLALGRDVIDA 60 Query: 61 NPELGYEELETSKLIRSELELIGIKYRYPVAI----TGVIGYIGTGEP-PFVALRADMDA 115 + +G + ET G R+ A GV+ + TG P P +A R DMDA Sbjct: 61 DSRMGLPDEETLARAFERAREQGAPERWLPAFEGGFAGVVATLDTGRPGPTLAFRVDMDA 120 Query: 116 LPIQEGVEWEHK-------SKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIF 168 L + E + H+ S AG MHACGHDGH + LG A +L ++ L G + LIF Sbjct: 121 LDLNEQHDDSHRPHRDHFASCNAGMMHACGHDGHTAIGLGLAHVLKQYAAQLNGVIKLIF 180 Query: 169 QPAEEGLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFLAGAGVFEAVITGK 228 QPAEEG GA+ M G + +V+ IH+ +P G +F+A F+ +G Sbjct: 181 QPAEEGTRGARAMVAAGVVDDVDYFTAIHIGTGVPAGTVVCGGDNFMA-TTKFDVQFSGV 239 Query: 229 GGHA 232 HA Sbjct: 240 AAHA 243 >4O23-A nrPDB Length = 384 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 78/353 (22%), Positives = 133/353 (37%), Gaps = 63/353 (17%) Query: 105 PFVALRADMDALPIQEGVEW--------EHKSKIAGKMHACGHDGHVTMLLGAAKILHEH 156 P V D +P +W E ++ G+ A + + + +H Sbjct: 64 PVVCFAGHTDVVPTGPVEKWDSPPFEPAERDGRLYGRGAADMKTSIACFVTACERFVAKH 123 Query: 157 RHHLQGTVVLIFQPAEEG--LSGAKKMREEGALKNVEAIFGI--------HLSARIPFGK 206 +H QG++ L+ EEG L G K+ + ++ + I L I G+ Sbjct: 124 PNH-QGSIALLITSDEEGDALDGTTKVVDVLKARDELIDYCIVGEPTAVDKLGDMIKNGR 182 Query: 207 AASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRE-TDPLDS 265 S +G+ + GK GH A P I+PV + +L L Q V E + Sbjct: 183 RGSLSGNL---------TVKGKQGHIAYPHLAINPVHTFAPALLELTQEVWDEGNEYFPP 233 Query: 266 KVVTVSKVNGGN-AFNVIPDSITIGGTLRAFTGFTQ--LQQRVKEVITKQAAVH----RC 318 +S +NGG A NVIP + + R T T+ L+QRV ++ K + C Sbjct: 234 TSFQISNINGGTGATNVIPGELNVKFNFRFSTESTEAGLKQRVHAILDKHGVQYDLQWSC 293 Query: 319 NASVNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIP 378 + LT G+ V R + + +EA + S T Sbjct: 294 SGQPFLTQAGK---------------LTDVARAAIAETCGIEA-------ELSTTGGTSD 331 Query: 379 GHFSLLGMQDETNGYASSHSPLYRINEDV----LPYGAAIHASMAVQYLKEKA 427 G F + + E S++ +++INE+V +P +A++ + + L A Sbjct: 332 GRF-IKAIAQELIELGPSNATIHQINENVRLNDIPKLSAVYEGILARLLAGNA 383 >1CG2-A nrPDB Length = 393 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 12/155 (7%) Query: 141 GHVTMLLGAAKILHEHRHHLQGTVVLIFQPAEE-GLSGAKKMREEGALKNVEAIFGIHLS 199 G ++L K+L E+ GT+ ++F EE G G++ + +E EA ++ Sbjct: 122 GGNAVILHTLKLLKEYGVRDYGTITVLFNTDEEKGSFGSRDLIQE------EAKLADYVL 175 Query: 200 ARIPFGKAASRAGSFLAGAGVFEAVITGKGGHA-AIPQHTIDPVVAASSIVLSLQQLVSR 258 + P + +G + ITGK HA A P+ ++ +V AS +VL + Sbjct: 176 SFEPTSAGDEKLSLGTSGIAYVQVNITGKASHAGAAPELGVNALVEASDLVLRTMNI--- 232 Query: 259 ETDPLDSKVVTVSKVNGGNAFNVIPDSITIGGTLR 293 D + + GN N+IP S T+ +R Sbjct: 233 -DDKAKNLRFNWTIAKAGNVSNIIPASATLNADVR 266 >3RZA-A nrPDB Length = 396 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 50/230 (21%), Positives = 95/230 (41%), Gaps = 33/230 (14%) Query: 102 GEPPFVALRADMDAL-------PI--QEGVEWEHKSKIAGKMHACGHDGHVTMLLGAAKI 152 GE P + L + MD + PI +G + + I G G + +L ++ Sbjct: 88 GEVPKLYLTSHMDTVVPAINVKPIVKDDGYIYSDGTTILGADDKAG----LAAMLEVLQV 143 Query: 153 LHEHRHHLQGTVVLIFQPAEE-GLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRA 211 + E + G + + EE GL GAK++ E ++A FG + A G A Sbjct: 144 IKEQQIP-HGQIQFVITVGEESGLIGAKELNSE----LLDADFGYAIDASADVGTTVVGA 198 Query: 212 GSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVS 271 + + + A I GK HA+ P+ + + A+ ++ ++ + D + + + Sbjct: 199 PTQM----LISAKIIGKTAHASTPKEGVSAINIAAK---AISRMKLGQVDEITT--ANIG 249 Query: 272 KVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS 321 K +GG+A N++ D + + R+ +R+K + V AS Sbjct: 250 KFHGGSATNIVADEVILEAEARSHD-----PERIKTQVKHMTDVFETTAS 294 >2AP1-A nrPDB Length = 327 Score = 32.0 bits (71), Expect = 0.49, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 4/89 (4%) Query: 219 GVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVNGGNA 278 G E ++G+G A + QH D + A I+ +L + + + + + V GN Sbjct: 207 GCIENYLSGRG-FAWLYQHYYDQSLQAPEII-ALWEQGDEQAHAHVERYLDLLAVCLGNI 264 Query: 279 FNVI-PDSITIGGTLRAFTGF-TQLQQRV 305 ++ PD + IGG L FT TQL +R+ Sbjct: 265 LTIVDPDLLVIGGGLSNFTAITTQLAERL 293 >3CT9-A nrPDB Length = 356 Score = 31.2 bits (69), Expect = 0.87, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 33/78 (42%) Query: 217 GAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVNGG 276 G V + TGK GHAA + + I +E+ L ++V+ +N G Sbjct: 174 GLMVLDVTATGKAGHAARDEGDNAIYKVLNDIAWFRDYRFEKESPLLGPVKMSVTVINAG 233 Query: 277 NAFNVIPDSITIGGTLRA 294 NV+PD T +R+ Sbjct: 234 TQHNVVPDKCTFVVDIRS 251 >5C5I-A nrPDB Length = 316 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 212 GSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIV----LSLQQLVSRETDPLDSKV 267 G L A + EA+ +G+ GHA + ++P+ AS +++ +S TDP + Sbjct: 232 GPILDSAALIEALDSGRIGHAVLDVFEVEPLPEASPFWGHPKVTVLPHISAATDPETASA 291 Query: 268 VTVSKVNGGNAFNVIPDSITI 288 + + V A IP S+ + Sbjct: 292 IVGAHVADYRATGRIPPSVDL 312 >4PU3-A nrPDB Length = 454 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 1/48 (2%) Query: 301 LQQRVKEVITKQAAVHRCNASVNLTPNGREPMP-PTVNNKDLYKQFKK 347 LQ + ++T A H N S +TP+G EP P + + D+Y+ F++ Sbjct: 314 LQWALFNLLTGNADAHGKNYSFFMTPSGMEPTPWYDLVSVDMYEDFEQ 361 >1BZS-A nrPDB Length = 165 Score = 29.3 bits (64), Expect = 3.6, Method: Compositional matrix adjust. Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 1/84 (1%) Query: 161 QGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFLAGAGV 220 G + FQP + G+ G E N A + + L A FG + A S GA + Sbjct: 79 NGILAHAFQPGQ-GIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALM 137 Query: 221 FEAVITGKGGHAAIPQHTIDPVVA 244 + + + ++PQ ID + A Sbjct: 138 YPNYAFRETSNYSLPQDDIDGIQA 161 >2RB7-A nrPDB Length = 364 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 15/60 (25%), Positives = 26/60 (43%) Query: 225 ITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVNGGNAFNVIPD 284 TGK H A P ++ V L+ L + E + + V + ++ G + N +PD Sbjct: 184 CTGKAAHGARPWMGVNAVDLLMEDYTRLKTLFAEENEDHWHRTVNLGRIRAGESTNKVPD 243 >5JLC-A nrPDB Length = 515 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 346 KKVVRDLLGQEAFVEAAPVMGSEDFSYFAET 376 KK V+ L +EAFV P++ E + YF + Sbjct: 133 KKFVKGALTKEAFVRYVPLIAEEIYKYFRNS 163 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1XMB-A nrPDB 664 0.0 4O23-A nrPDB 384 e-107 3IO1-A nrPDB 318 3e-87 Sequences not found previously or not previously below threshold: 3ISZ-A nrPDB 220 1e-57 4H2K-A nrPDB 99 5e-21 4ONW-A nrPDB 90 1e-18 3RZA-A nrPDB 63 2e-10 1CG2-A nrPDB 52 5e-07 2RB7-A nrPDB 48 8e-06 3PFO-A nrPDB 41 0.002 3CT9-A nrPDB 41 0.002 3TX8-A nrPDB 39 0.004 2QYV-A nrPDB 38 0.008 3DLJ-A nrPDB 36 0.036 5ZMY-A nrPDB 36 0.046 3MY9-A nrPDB 31 1.7 2Y4R-A nrPDB 30 2.3 >1XMB-A nrPDB Length = 418 Score = 664 bits (1713), Expect = 0.0, Method: Composition-based stats. Identities = 418/418 (100%), Positives = 418/418 (100%) Query: 22 SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELEL 81 SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELEL Sbjct: 1 SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELEL 60 Query: 82 IGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDG 141 IGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDG Sbjct: 61 IGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACGHDG 120 Query: 142 HVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSAR 201 HVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSAR Sbjct: 121 HVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSAR 180 Query: 202 IPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETD 261 IPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETD Sbjct: 181 IPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETD 240 Query: 262 PLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS 321 PLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS Sbjct: 241 PLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS 300 Query: 322 VNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHF 381 VNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHF Sbjct: 301 VNLTPNGREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHF 360 Query: 382 SLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL 439 SLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL Sbjct: 361 SLLGMQDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLKEKASKGSVSGFHEEL 418 >4O23-A nrPDB Length = 384 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 86/397 (21%), Positives = 147/397 (37%), Gaps = 64/397 (16%) Query: 62 PELGYEELETSKLIRSELELIG-IKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQE 120 P + ++ + KL+ L IG T I + P V D +P Sbjct: 20 PSVTPDDRDCQKLLAERLHKIGFAAEELHFGDTKNIWLRRGTKAPVVCFAGHTDVVPTGP 79 Query: 121 GVEW--------EHKSKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIFQPAE 172 +W E ++ G+ A + + + +H +H QG++ L+ E Sbjct: 80 VEKWDSPPFEPAERDGRLYGRGAADMKTSIACFVTACERFVAKHPNH-QGSIALLITSDE 138 Query: 173 EG--LSGAKKMREEGALKNVEAIFGI--------HLSARIPFGKAASRAGSFLAGAGVFE 222 EG L G K+ + ++ + I L I G+ S +G+ Sbjct: 139 EGDALDGTTKVVDVLKARDELIDYCIVGEPTAVDKLGDMIKNGRRGSLSGNL-------- 190 Query: 223 AVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRE-TDPLDSKVVTVSKVNGGN-AFN 280 + GK GH A P I+PV + +L L Q V E + +S +NGG A N Sbjct: 191 -TVKGKQGHIAYPHLAINPVHTFAPALLELTQEVWDEGNEYFPPTSFQISNINGGTGATN 249 Query: 281 VIPDSITIGGTLRAFTGFTQ--LQQRVKEVITKQAAVH----RCNASVNLTPNGREPMPP 334 VIP + + R T T+ L+QRV ++ K + C+ LT G+ Sbjct: 250 VIPGELNVKFNFRFSTESTEAGLKQRVHAILDKHGVQYDLQWSCSGQPFLTQAGK----- 304 Query: 335 TVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHFSLLGMQDETNGYA 394 V R + + +EA + S T G F + + E Sbjct: 305 ----------LTDVARAAIAETCGIEA-------ELSTTGGTSDGRF-IKAIAQELIELG 346 Query: 395 SSHSPLYRINEDV----LPYGAAIHASMAVQYLKEKA 427 S++ +++INE+V +P +A++ + + L A Sbjct: 347 PSNATIHQINENVRLNDIPKLSAVYEGILARLLAGNA 383 >3IO1-A nrPDB Length = 445 Score = 318 bits (815), Expect = 3e-87, Method: Composition-based stats. Identities = 91/336 (27%), Positives = 146/336 (43%), Gaps = 37/336 (11%) Query: 9 LTFQLLLFLLSVS-SESPWIAEDTSQIQTKLLEFAKSPEVFDWMVKI-------RRKIHE 60 ++ QL +L ++ S + W + ++ LEF + +V D + + R I Sbjct: 1 MSLQLDEYLRQLAPSMTQWRRDFHLHAESGWLEFRTASKVADILDGLGYQLALGRDVIDA 60 Query: 61 NPELGYEELETSKLIRSELELIGIKYRYPVAI----TGVIGYIGTGEP-PFVALRADMDA 115 + +G + ET G R+ A GV+ + TG P P +A R DMDA Sbjct: 61 DSRMGLPDEETLARAFERAREQGAPERWLPAFEGGFAGVVATLDTGRPGPTLAFRVDMDA 120 Query: 116 LPIQEGVEWEHK-------SKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIF 168 L + E + H+ S AG MHACGHDGH + LG A +L ++ L G + LIF Sbjct: 121 LDLNEQHDDSHRPHRDHFASCNAGMMHACGHDGHTAIGLGLAHVLKQYAAQLNGVIKLIF 180 Query: 169 QPAEEGLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFLAGAGVFEAVITGK 228 QPAEEG GA+ M G + +V+ IH+ +P G +F+A F+ +G Sbjct: 181 QPAEEGTRGARAMVAAGVVDDVDYFTAIHIGTGVPAGTVVCGGDNFMA-TTKFDVQFSGV 239 Query: 229 GGHA-AIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVN-----GGNAFNVI 282 HA P+ + ++AA+ + + S+VN G NV+ Sbjct: 240 AAHAGGKPEDGRNALLAAAQA--------ALGLHAIPPHSAGASRVNVGVMQAGTGRNVV 291 Query: 283 PDSITIGGTLRAFTGFTQ--LQQRVKEVITKQAAVH 316 P S + R + + +R + V+ AA++ Sbjct: 292 PSSALLKVETRGESEAINQYVFERAQHVVAGAAAMY 327 >3ISZ-A nrPDB Length = 377 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 72/394 (18%), Positives = 136/394 (34%), Gaps = 66/394 (16%) Query: 62 PELGYEELETSKLIRSELELIGIKYRYPV--AITGVIGYIGTGEPPFVALRADMDALPIQ 119 P + + ++I LE +G + + + GT E P +A D +P Sbjct: 16 PSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSE-PVIAFAGHTDVVPTG 74 Query: 120 EGVEWEH--------KSKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIFQPA 171 + +W + G+ A M++ A + + + +H +GT+ L+ Sbjct: 75 DENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANPNH-KGTIALLITSD 133 Query: 172 EEGL--SGAKKMREEGALKNVEAIFGI--------HLSARIPFGKAASRAGSFLAGAGVF 221 EE G + E ++ + + + +L + G+ S G+ Sbjct: 134 EEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRGSITGNLY------ 187 Query: 222 EAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRE-TDPLDSKVVTVSKVNGGNAF- 279 I G GH A P +P+ A+ + L + + + ++ ++ G Sbjct: 188 ---IQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAGTGSN 244 Query: 280 NVIPDSITIGGTLRAFTGFTQ--LQQRVKEVITKQAAVHRC----NASVNLTPNGREPMP 333 NVIP + I LR T T ++Q+V E++ K +R + LT G+ Sbjct: 245 NVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGK---- 300 Query: 334 PTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHFSLLGMQDETNGY 393 + + + + G T G F L M E + Sbjct: 301 -----------LLDSITSAIEETIGITPKAETG-------GGTSDGRFIAL-MGAEVVEF 341 Query: 394 ASSHSPLYRINEDV----LPYGAAIHASMAVQYL 423 +S ++++NE V L I+ M V L Sbjct: 342 GPLNSTIHKVNECVSVEDLGKCGEIYHKMLVNLL 375 >4H2K-A nrPDB Length = 269 Score = 98.7 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 65/185 (35%), Gaps = 25/185 (13%) Query: 62 PELGYEELETSKLIRSELELIGIKYRYPV--AITGVIGYIGTGEPPFVALRADMDALPIQ 119 P + + ++I LE +G + + + GT E P +A D +P Sbjct: 19 PSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSE-PVIAFAGHTDVVPTG 77 Query: 120 EGVEWEH--------KSKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIFQPA 171 + +W + G+ A M++ A + + + +H +GT+ L+ Sbjct: 78 DENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANPNH-KGTIALLITSD 136 Query: 172 EEGL--SGAKKMREEGALKNVEAIFGI--------HLSARIPFGKAASRAGSFLAGAGVF 221 EE G + E ++ + + + +L + G+ G FL G Sbjct: 137 EEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRG---GGFLTKPGKL 193 Query: 222 EAVIT 226 IT Sbjct: 194 LDSIT 198 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 28/84 (33%), Gaps = 12/84 (14%) Query: 344 QFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGHFSLLGMQDETNGYASSHSPLYRI 403 + + + + + G T G F L M E + +S ++++ Sbjct: 192 KLLDSITSAIEETIGITPKAETG-------GGTSDGRFIAL-MGAEVVEFGPLNSTIHKV 243 Query: 404 NEDV----LPYGAAIHASMAVQYL 423 NE V L I+ M V L Sbjct: 244 NECVSVEDLGKCGEIYHKMLVNLL 267 >4ONW-A nrPDB Length = 268 Score = 90.2 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 44/135 (32%), Gaps = 22/135 (16%) Query: 103 EPPFVALRADMDALPIQEGVEWEH--------KSKIAGKMHACGHDGHVTMLLGAAKILH 154 + P D +P +W + G+ A M++ + + Sbjct: 61 QSPLFVFAGHTDVVPAGPLSQWHTPPFEPTVIDGFLHGRGAADMKGSLACMIVAVERFIA 120 Query: 155 EHRHHLQGTVVLIFQPAEEG--LSGAKKMREEGALKNVEAIFGI--------HLSARIPF 204 EH H QG++ + EEG ++G ++ E +N I + + Sbjct: 121 EHPDH-QGSIGFLITSDEEGPFINGTVRVVETLMARNELIDMCIVGEPSSTLAVGDVVKN 179 Query: 205 GKAASRAGSFLAGAG 219 G+ G FL G Sbjct: 180 GRRG---GGFLTDTG 191 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 19/58 (32%), Gaps = 5/58 (8%) Query: 370 FSYFAETIPGHFSLLGMQDETNGYASSHSPLYRINEDV----LPYGAAIHASMAVQYL 423 T G F + M + ++ ++++NE V L ++ L Sbjct: 211 LLTTGGTSDGRF-IAQMGAQVVELGPVNATIHKVNECVRIADLEKLTDMYQKTLNHLL 267 >3RZA-A nrPDB Length = 396 Score = 63.2 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 65/338 (19%), Positives = 118/338 (34%), Gaps = 41/338 (12%) Query: 97 GYIGTGEPPFVALRADMD----ALPIQEGVEWEHKSKIAGKMH----ACGHDGHVTMLLG 148 I GE P + L + MD A+ ++ V+ I A G ML Sbjct: 83 STIEEGEVPKLYLTSHMDTVVPAINVKPIVKD--DGYIYSDGTTILGADDKAGLAAMLEV 140 Query: 149 AAKILHEHRHHLQGTVVLIFQPAEE-GLSGAKKMREEGALKNVEAIFGIHLSARIPFGKA 207 I + H G + + EE GL GAK++ E ++A FG + A G Sbjct: 141 LQVIKEQQIPH--GQIQFVITVGEESGLIGAKELNSEL----LDADFGYAIDASADVGTT 194 Query: 208 ASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKV 267 A + + + I GK HA+ P+ + + A+ + ++ E Sbjct: 195 VVGAPTQMLISAK----IIGKTAHASTPKEGVSAINIAAKAISRMKLGQVDEI-----TT 245 Query: 268 VTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNASVNLTPN 327 + K +GG+A N++ D + + R +++ +VK + V T Sbjct: 246 ANIGKFHGGSATNIVADEVILEAEAR-SHDPERIKTQVKHMTD-----------VFETTA 293 Query: 328 GREPMPPTVNNKDLYKQFKKVVRDLLGQEAFVEAAPVMGSEDFSYFAETIPGH-FSLLGM 386 V + Y FK + + + A A + S + G + G+ Sbjct: 294 SELGGKAEVTVEQSYPGFKINDNEAVVKIAQESARNLGLSANTIISGGGSDGSIINTFGI 353 Query: 387 QDETNGYASSHSPLYRINEDVLPYGAAIHASMAVQYLK 424 G + ++ NE + + AS ++ +K Sbjct: 354 PSVILGVG--YEKIHTTNERMPIKSLNLLASQVLEIIK 389 >1CG2-A nrPDB Length = 393 Score = 52.1 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 43/168 (25%), Positives = 69/168 (41%), Gaps = 13/168 (7%) Query: 129 KIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVVLIFQPAEE-GLSGAKKMREEGAL 187 K G A G+ +L K+L E+ GT+ ++F EE G G++ + +E A Sbjct: 111 KAYGPGIADDKGGNAVILHTL-KLLKEYGVRDYGTITVLFNTDEEKGSFGSRDLIQEEA- 168 Query: 188 KNVEAIFGIHLSARIPFGKAASRAGSFLAGAGVFEAVITGKGGHA-AIPQHTIDPVVAAS 246 A + + + S S G + ITGK HA A P+ ++ +V AS Sbjct: 169 --KLADYVLSFEPTSAGDEKLSLGTS---GIAYVQVNITGKASHAGAAPELGVNALVEAS 223 Query: 247 SIVLSLQQLVSRETDPLDSKVVTVSKVNGGNAFNVIPDSITIGGTLRA 294 +VL + D + + GN N+IP S T+ +R Sbjct: 224 DLVLRTMNI----DDKAKNLRFNWTIAKAGNVSNIIPASATLNADVRY 267 >2RB7-A nrPDB Length = 364 Score = 47.8 bits (112), Expect = 8e-06, Method: Composition-based stats. Identities = 37/195 (18%), Positives = 66/195 (33%), Gaps = 18/195 (9%) Query: 107 VALRADMDALPIQEG--VEWEHKSKIAGKMHACGHD----GHVTMLLGAAKILHEHRHHL 160 + L A +D + ++ V ++ G+ G V + R Sbjct: 68 LLLMAHIDVVDAEDDLFVPRVENDRLYGRGANDDKYAVALGLVMFRDRLNALKAAGRSQK 127 Query: 161 QGTVVLIFQPAEE--GLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFLAGA 218 + L+ EE G++GA K AL + A + + L P G Sbjct: 128 DMALGLLITGDEEIGGMNGAAK-----ALPLIRADYVVALDGGNPQQVITKEKG-----I 177 Query: 219 GVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVNGGNA 278 + TGK H A P ++ V L+ L + E + + V + ++ G + Sbjct: 178 IDIKLTCTGKAAHGARPWMGVNAVDLLMEDYTRLKTLFAEENEDHWHRTVNLGRIRAGES 237 Query: 279 FNVIPDSITIGGTLR 293 N +PD +R Sbjct: 238 TNKVPDVAEGWFNIR 252 >3PFO-A nrPDB Length = 433 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 33/208 (15%), Positives = 59/208 (28%), Gaps = 29/208 (13%) Query: 89 PVAITGVIGYIGT-GEPPFVALRADMDALPIQEGVEWE--------HKSKIAGKMHACGH 139 P V+ + G+ + L+ +D +P W + G+ Sbjct: 87 PAGSMQVVATADSDGKGRSLILQGHIDVVPEGPVDLWSDPPYEAKVRDGWMIGRGAQDMK 146 Query: 140 DGHVTMLLGAAKILHEHRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLS 199 G M+ I V E +GA G + I Sbjct: 147 GGVSAMIFALDAIRTAGYAPDARVHVQTVTEEESTGNGALSTLMRGYRADACLIPE---- 202 Query: 200 ARIPFGKAASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRE 259 P G +RA GA F + G H A + +++A ++ + ++ Sbjct: 203 ---PTGHTLTRA---QVGAVWFRLRVRGTPVHVAYSETGTSAILSAMHLIRAFEEYTKEL 256 Query: 260 T-----DPL-----DSKVVTVSKVNGGN 277 DP + V + GG+ Sbjct: 257 NAQAVRDPWFGQVKNPIKFNVGIIKGGD 284 >3CT9-A nrPDB Length = 356 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 46/265 (17%), Positives = 83/265 (31%), Gaps = 30/265 (11%) Query: 103 EPPFVALRADMDAL-PIQEGVEW-----EHKSKIAGKMHACGHDGHVTMLLGAAKILHEH 156 + P + L + +D + P+ + E K+ G V++L ++ + Sbjct: 65 KKPTILLNSHIDTVKPVNGWRKDPFTPREENGKLYGLGSNDAGASVVSLL----QVFLQL 120 Query: 157 RHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFLA 216 Q ++ EE +SG + + + + P + A Sbjct: 121 CRTSQNYNLIYLASCEEEVSGKEGIESVLPGLPPVSFAIV----GEPTEMQPAIAEK--- 173 Query: 217 GAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSKVVTVSKVNGG 276 G V + TGK GHAA + + I +E+ L ++V+ +N G Sbjct: 174 GLMVLDVTATGKAGHAARDEGDNAIYKVLNDIAWFRDYRFEKESPLLGPVKMSVTVINAG 233 Query: 277 NAFNVIPDS----ITIGGTLRAFTGFTQLQQRVKEVITKQAAVHRCNAS------VNLTP 326 NV+PD + I + R +A R N+S + Sbjct: 234 TQHNVVPDKCTFVVDIRSNELYSNEDLFAEIRKHIACDAKARSFRLNSSRIDEKHPFVQK 293 Query: 327 N---GREPMPPTVNNKDLYKQFKKV 348 GR P + F V Sbjct: 294 AVKMGRIPFGSPTLSDQALMSFASV 318 >3TX8-A nrPDB Length = 369 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 39/211 (18%), Positives = 63/211 (29%), Gaps = 24/211 (11%) Query: 95 VIGYIGTGEPPFVALRADMDALPIQEGVEWE-HKSKIAGKMHACGHDGHVTMLLGAAKIL 153 V+ G V L +D +PI + + + G G L A + Sbjct: 60 VLARTNRGLASRVMLAGHIDTVPIADNLPSRVEDGIMYGCGTVDMKSGLAVYLHTFATLA 119 Query: 154 HEHRHHLQGTVVLIFQPAEE---GLSGAKKMREE----GALKNVEAIFGIHLSARIPFGK 206 L+ + LI EE L+G +R+E A A+ G I G Sbjct: 120 T--STELKHDLTLIAYECEEVADHLNGLGHIRDEHPEWLAAD--LALLGEPTGGWIEAGC 175 Query: 207 AASRAGSFLAGAGVFEAVITGKGGHAAIPQHTIDPVVAASSIVLSLQQLVSRETDPLDSK 266 + + G H+A + + S I+ + + E + Sbjct: 176 QGNL---------RIKVTAHGVRAHSARSWLGDNAMHKLSPIISKVAAYKAAEVNIDGLT 226 Query: 267 VVTVSKV---NGGNAFNVIPDSITIGGTLRA 294 + G A NVIPD + R Sbjct: 227 YREGLNIVFCESGVANNVIPDLAWMNLNFRF 257 >2QYV-A nrPDB Length = 487 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 55/287 (19%), Positives = 93/287 (32%), Gaps = 49/287 (17%) Query: 56 RKIHENPELGYEELETSKLI---------RSELELIGIKYRYPVAITGVIGYIGTGEPPF 106 +I P Y+E + ++ I +E + +G A G+ P Sbjct: 18 DQICAIPHPSYKEEQLAQFIINWAKTKGFFAERDEVGNVLIRKPATVGM-----ENRKPV 72 Query: 107 VALRADMDALPI---QEGVEWEHKSKI--------AGKMHACGHDGHVTMLLGAAKILHE 155 V L+A +D +P ++ + K G D + M A + Sbjct: 73 V-LQAHLDMVPQANEGTNHNFDQDPILPYIDGDWVKAKGTTLGADNGIGMASALAVLESN 131 Query: 156 HRHHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSARIPFGKAASRAGSFL 215 H + V+L E G+ GA +R + + I G A Sbjct: 132 DIAHPELEVLLTMT-EERGMEGAIGLRPNWLRSEILINTDTEENGEIYIGCAGGENADLE 190 Query: 216 AGAGV--------FEAVITG-KGGHAAIPQHT--IDPVVAASSIVLSLQQLVSRETDP-L 263 ++ V+ G +GGH+ + HT + + + LQQ P Sbjct: 191 LPIEYQVNNFEHCYQVVLKGLRGGHSGVDIHTGRANAIKVLLRFLAELQQ-----NQPHF 245 Query: 264 DSKVVTVSKVNGGNAFNVIPDSITIGGTLRAFTGFTQLQQRVKEVIT 310 D T++ + GG+ N IP TL T LQ V++ Sbjct: 246 D---FTLANIRGGSIRNAIPRESVA--TLVFNGDITVLQSAVQKFAD 287 >3DLJ-A nrPDB Length = 485 Score = 35.9 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 37/128 (28%), Gaps = 22/128 (17%) Query: 106 FVALRADMDALPIQEGVEW--------EHKSKIAGKMHACGHDGHVTMLLGAAKILHEHR 157 V +D P G W E K+ G+ + + + + Sbjct: 104 TVCFYGHLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDNKGPVLAWINAVSAFRALEQ 163 Query: 158 HHLQGTVVLIFQPAEEGLSGAKKMREEGALKNVEAIFG----------IHLSARIPFGKA 207 L + I + EE S A EE K + F + +S R P Sbjct: 164 D-LPVNIKFIIEGMEEAGSVA---LEELVEKEKDRFFSGVDYIVISDNLWISQRKPAITY 219 Query: 208 ASRAGSFL 215 +R S+ Sbjct: 220 GTRGNSYF 227 >5ZMY-A nrPDB Length = 314 Score = 35.5 bits (80), Expect = 0.046, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 41/120 (34%), Gaps = 20/120 (16%) Query: 33 QIQTKLLEFAKSPEVFDWMVKIRRKIHENPELGYEELETSKLIRSELELIGIKYRYPVAI 92 +L E P W V R + ++G + + EL GI+ +P I Sbjct: 167 HFSKRLRELGVKPAFIAWTVPFTRTLDAFMDMGLVDDP--AYLLFELTDCGIRGGHPGTI 224 Query: 93 TGVIGYIGTGEPPFVALRADMDALPIQEGVEW---EHKSKIAGKMHACGHD-GHVTMLLG 148 G LRA D LP ++W + G A + GHV + LG Sbjct: 225 RG--------------LRAHTDFLPPGRQIQWTVCNKIGNLFGPAAAAIEEGGHVAIGLG 270 >3MY9-A nrPDB Length = 377 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 3/58 (5%) Query: 81 LIGIKYRYPVAITGVIGYIGTGEPPFVALRADMDALPIQEGVEWEHKSKIAGKMHACG 138 + R+ A+ G + T P +A + DA+ + E V + I+ K+ CG Sbjct: 223 EQPVPRRHLDAMAGFAAALDT---PILADESCFDAVDLMEVVRRQAADAISVKIMKCG 277 >2Y4R-A nrPDB Length = 292 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 30/97 (30%), Gaps = 14/97 (14%) Query: 107 VALRADM-DALPIQEGVEWEHKSKIAGKMHACGHDGHVTMLLGAAKILHEHRHHLQGTVV 165 + + M D + + E + + G + G + + G ++L H L Sbjct: 16 LYFQGHMLDWVDGRPAAELSVRDR--GLAYGDGLFETLAVRAGTPRLLERHLARL----- 68 Query: 166 LIFQPAEEGLSGAKKMREEGALKNVEAIFGIHLSARI 202 EEG + AL+ F L + Sbjct: 69 ------EEGCRRLAIPLDTAALRQELLAFCAALGDGV 99 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.126 0.320 Lambda K H 0.267 0.0373 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,497,566 Number of Sequences: 36641 Number of extensions: 555802 Number of successful extensions: 2140 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 2085 Number of HSP's gapped (non-prelim): 45 length of query: 439 length of database: 10,336,785 effective HSP length: 100 effective length of query: 339 effective length of database: 6,672,685 effective search space: 2262040215 effective search space used: 2262040215 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.9 bits)