BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P54868 (508 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2WYA-A nrPDB 962 0.0 2P8U-A nrPDB 680 0.0 2FA3-A nrPDB 444 e-125 5HWO-A nrPDB 220 1e-57 1YSL-B nrPDB 141 8e-34 1XPM-A nrPDB 111 7e-25 5KP5-A nrPDB 99 4e-21 4YXV-A nrPDB 87 1e-17 3LEH-A nrPDB 79 4e-15 6ESQ-I nrPDB 58 9e-09 4YLT-A nrPDB 34 0.12 3ZU2-A nrPDB 33 0.21 5AQB-A nrPDB 28 6.8 >2WYA-A nrPDB Length = 460 Score = 962 bits (2486), Expect = 0.0, Method: Compositional matrix adjust. Identities = 458/458 (100%), Positives = 458/458 (100%) Query: 51 PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVV 110 PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVV Sbjct: 3 PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVV 62 Query: 111 QRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT 170 QRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT Sbjct: 63 QRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT 122 Query: 171 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGL 230 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGL Sbjct: 123 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGL 182 Query: 231 RGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF 290 RGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF Sbjct: 183 RGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF 242 Query: 291 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK 350 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK Sbjct: 243 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK 302 Query: 351 DLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAF 410 DLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAF Sbjct: 303 DLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAF 362 Query: 411 SYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQF 470 SYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQF Sbjct: 363 SYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQF 422 Query: 471 YHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV 508 YHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV Sbjct: 423 YHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV 460 >2P8U-A nrPDB Length = 478 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/455 (68%), Positives = 380/455 (83%) Query: 53 DVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQR 112 DVGI+ALE+YFP+QYVDQ +LEKY+ V+AGKYT+GLGQ +MGFC+ +EDINSLC+TVVQ Sbjct: 24 DVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQN 83 Query: 113 LMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTAS 172 LMER L +D +GRLEVGTETIIDKSK+VKT LM+LF++SGNTDIEGIDTTNACYGGTA+ Sbjct: 84 LMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAA 143 Query: 173 LFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRG 232 +FNA NW+ESSSWDGRYA+VV GDIAVY +GNARPTGG GAVA+LIGP APL ERGLRG Sbjct: 144 VFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRG 203 Query: 233 THMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTL 292 THM++ YDFYKP++ SEYPIVDGKLSIQCYL ALDRCY+ Y KKI QW++ G+D+ FTL Sbjct: 204 THMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTL 263 Query: 293 DDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDL 352 +D +MIFH+P+CK+VQKSLAR++ NDFL+ + + S+Y GLEAFG +KLEDTY ++D+ Sbjct: 264 NDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDV 323 Query: 353 DKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSY 412 +KA +KAS ++F +KTKASL +S NGNMYTSS+YG LAS+L+ +S Q+LAG RIG FSY Sbjct: 324 EKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSY 383 Query: 413 GSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYH 472 GSGLAA+ +S +V+QDA PGS LDK+ +S DL RL SR V+P+ F E M RE +H Sbjct: 384 GSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHH 443 Query: 473 KVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRP 507 VN+ P G +SLF GTWYL RVDE+HRR YARRP Sbjct: 444 LVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRP 478 >2FA3-A nrPDB Length = 450 Score = 444 bits (1143), Expect = e-125, Method: Compositional matrix adjust. Identities = 215/457 (47%), Positives = 306/457 (66%), Gaps = 10/457 (2%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 K+VGILA+++YFP V Q LE ++ GKYT+GLGQ + FC+ ED+ S+ V Sbjct: 2 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQDCLAFCTELEDVISMSFNAVT 61 Query: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 L+E+ ++ +GRLEVG+ET+IDKSK++KT LM+LF+ GNTD+EG+D+TNACYGGTA Sbjct: 62 SLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQLFEKCGNTDVEGVDSTNACYGGTA 121 Query: 172 SLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLR 231 +L N NW+ES+SWDGRY +V+C D AVY G ARPTGGA A+AMLIGP AP+ E LR Sbjct: 122 ALLNCVNWVESNSWDGRYGLVICTDSAVYAEGPARPTGGAAAIAMLIGPDAPIVFESKLR 181 Query: 232 GTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFT 291 G+HM +VYDFYKPNLASEYP+VDGKLS CYL ALD CY K + N++++ + F+ Sbjct: 182 GSHMAHVYDFYKPNLASEYPVVDGKLSQTCYLMALDSCY----KHLCNKFEKL-EGKEFS 236 Query: 292 LDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKD 351 ++D Y +FH+P+ K+VQKS ARL++NDFL +S + + + L L+++Y ++D Sbjct: 237 INDADYFVFHSPYNKLVQKSFARLLYNDFLRNASSIDEAAKEKFTPYSSLSLDESYQSRD 296 Query: 352 LDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS 411 L+K + ++ +D K + + + GNMYT+SLY ASL+ H+ +LAG R+ FS Sbjct: 297 LEKVSQQLAKTYYDAKVQPTTLVPKQVGNMYTASLYAAFASLV-HNKHSDLAGKRVVMFS 355 Query: 412 YGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFY 471 YGSG A+ FS R+ ++ +P S + ++S D+ +L +R +PE+F E M E Y Sbjct: 356 YGSGSTATMFSLRLCENQSPFSLSN--IASVMDVGGKLKARHEYAPEKFVETMKLMEHRY 413 Query: 472 HKVNF--SPPGDTNSLFPGTWYLERVDEQHRRKYARR 506 F S G + L PGT+YL+ VD +RR Y ++ Sbjct: 414 GAKEFVTSKEGILDLLAPGTYYLKEVDSLYRRFYGKK 450 >5HWO-A nrPDB Length = 420 Score = 220 bits (560), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 169/459 (36%), Positives = 233/459 (50%), Gaps = 52/459 (11%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 K VGI AL V P++YVD DL + V+ KYT GLG M ED +L T Sbjct: 5 KRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAA 64 Query: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 RL+ + + +G L VGTET ID SK V + + L + + DT +ACYGGTA Sbjct: 65 RLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLLKLP--RTMRTYDTQHACYGGTA 122 Query: 172 SLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNA-RPTGGAGAVAMLIGPKAP-LALERG 229 L A W+ S + G+ A+VVC DIA Y A PT G GAVA+L+ + LA++ G Sbjct: 123 GLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDLLAMDVG 182 Query: 230 LRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQN----QWKQAG 285 L G +VYDF++P + +VDG SI CYL AL Y +R+K +W A Sbjct: 183 LNGVCSMDVYDFWRP-VGRREALVDGHYSITCYLEALSGAYRGWREKALAAGLVRWSDA- 240 Query: 286 SDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLED 345 + L + +H PFCKM +K+ +L D L ++D S + EA Sbjct: 241 ----LPGEQLARIAYHVPFCKMARKAHTQLRLCD-LEDAADAAASTPESREA-------- 287 Query: 346 TYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGS 405 +A AS +D + SL L++ GN+YT+SLY LA LL H A LAG Sbjct: 288 --------QAKSAAS---YDAQVATSLGLNSRIGNVYTASLYLALAGLL-QHEAGALAGQ 335 Query: 406 RIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMN 465 RIG SYGSG AA F+S V + AA +++ + +DL LA R+ VS EE+ +M Sbjct: 336 RIGLLSYGSGCAAEFYSGTVGEKAA-----ERM--AKADLEAVLARRERVSIEEYERLM- 387 Query: 466 QREQFYHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYA 504 K+ P + + PG + L + + HRR+YA Sbjct: 388 -------KLPADAP-EAVAPSPGAFRLTEIRD-HRRQYA 417 >1YSL-B nrPDB Length = 402 Score = 141 bits (355), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 110/370 (29%), Positives = 174/370 (47%), Gaps = 57/370 (15%) Query: 54 VGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRL 113 +GI + + P Y+D T L + NV+ GK+ +G+GQ +M + +DI + + + Sbjct: 22 IGIDKISFFVPPYYIDMTALAEARNVDPGKFHIGIGQDQMAVNPISQDIVTFAANAAEAI 81 Query: 114 MERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASL 173 + + +++ + VGTE+ ID+SKA VL L + ACYG TA L Sbjct: 82 LTKED--KEAIDMVIVGTESSIDESKAAAVVLHRLM--GIQPFARSFEIKEACYGATAGL 137 Query: 174 FNAANWMESSSWDGRYAMVVCGDIAVYP-SGNARPTGGAGAVAMLIGPKAPLALERGLRG 232 A N + + + +VV DIA Y + PT GAGAVAML+ + + + Sbjct: 138 QLAKNHV--ALHPDKKVLVVAADIAKYGLNSGGEPTQGAGAVAMLVASEPRILALKEDNV 195 Query: 233 THMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTL 292 +++YDF++P YP+VDG LS + Y+++ + + ++K+ G D Sbjct: 196 MLTQDIYDFWRPT-GHPYPMVDGPLSNETYIQSFAQVWDEHKKR-------TGLD----F 243 Query: 293 DDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDL 352 D + FH P+ KM +K+L L+ SD QT Sbjct: 244 ADYDALAFHIPYTKMGKKAL--------LAKISD-QT----------------------- 271 Query: 353 DKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSY 412 +A Q+ + + S+ S GN+YT SLY L SLL + + AG++IG FSY Sbjct: 272 -----EAEQERILARYEESIIYSRRVGNLYTGSLYLGLISLLENATTLT-AGNQIGLFSY 325 Query: 413 GSGLAASFFS 422 GSG A FF+ Sbjct: 326 GSGAVAEFFT 335 >1XPM-A nrPDB Length = 396 Score = 111 bits (278), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 110/377 (29%), Positives = 163/377 (43%), Gaps = 72/377 (19%) Query: 54 VGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRL 113 +GI + Y P YVD L + V+ K+ +G+GQT M V +DI S+ + + Sbjct: 3 IGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDI 62 Query: 114 MERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGI-------DTTNAC 166 + +G + V TE+ +D +KA + L GI + AC Sbjct: 63 I--TDEDKKKIGMVIVATESAVDAAKAAAVQIHNLL---------GIQPFARCFEMKEAC 111 Query: 167 YGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYP-SGNARPTGGAGAVAMLIGPKAPLA 225 Y T ++ A +++ ++ +V+ D A Y + PT GAGAVAM+I + Sbjct: 112 YAATPAIQLAKDYL--ATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSIL 169 Query: 226 LERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAG 285 + E+VYDF++P +YP+VDG LS Y+R+ + + Y K+ Q K Sbjct: 170 ALNEDAVAYTEDVYDFWRPT-GHKYPLVDGALSKDAYIRSFQQSWNEYAKR---QGK--- 222 Query: 286 SDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLED 345 +L D + FH PF KM +K+L ++ N A TQ L G E Sbjct: 223 -----SLADFASLCFHVPFTKMGKKALESIIDN----ADETTQERLRSGYE--------- 264 Query: 346 TYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGS 405 D D + + GN+YT SLY L SLL + Q AG Sbjct: 265 ----------------DAVD--------YNRYVGNIYTGSLYLSLISLLENRDLQ--AGE 298 Query: 406 RIGAFSYGSGLAASFFS 422 IG FSYGSG F+S Sbjct: 299 TIGLFSYGSGSVGEFYS 315 >5KP5-A nrPDB Length = 443 Score = 99.4 bits (246), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 121/484 (25%), Positives = 198/484 (40%), Gaps = 104/484 (21%) Query: 52 KDVGILALEVYFPAQYVD--------QTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDIN 103 + VGI AL VY A ++ Q D+ +++N+ + V L ED Sbjct: 26 QQVGIEALSVYGGAAQLELRKLAQARQLDISRFDNLMMKEKAVSL---------PYEDPV 76 Query: 104 SLCLTVVQRLMERIQ-LPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDT 162 S + + +++R+ + + +E+ ID K++ T + E S N + + Sbjct: 77 SYAVNAAKPIIDRLSDADKQRIEMVITCSESGIDFGKSMSTYIQEYLGLSRNCRM--FEL 134 Query: 163 TNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIA---VYPSGN--------ARPTGGA 211 ACY GTA L A N + S ++ G A+V+ DI+ V G A P+ GA Sbjct: 135 KQACYSGTAGLQMAINLILSQTFPGAKALVIATDISRFLVAEGGEAINYDWSFAEPSSGA 194 Query: 212 GAVAMLIGPKAPL-ALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCY 270 GAVA+L+ + ++ G G + V D +PN SE D LS+ YL + Y Sbjct: 195 GAVALLVSDTPHIFQIDVGCNGYYGYEVMDTCRPNPDSEAG--DADLSLLSYLDCCENAY 252 Query: 271 TSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTS 330 Y+ +++ G D + D Y+ FHTPF MV+ + +M Sbjct: 253 RHYQNRVE------GVDYRESFD---YLSFHTPFGGMVKGAHRNMM-------------- 289 Query: 331 LYKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCL 390 + L +A + F ++ L GN+ ++L+ L Sbjct: 290 -------------------RRLKRAKPAEIEADFQRRVMPGLVYCQQVGNIMGATLFLSL 330 Query: 391 ASLLSHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLA 450 AS + + RIG FSYGSG + F+S V+ + A +++ + +LA Sbjct: 331 ASTIDNGDFS--TPRRIGMFSYGSGCCSEFYSGVVTPEGAA-------IAAQQGISAQLA 381 Query: 451 SRKCVSPEEFTEIMNQREQFYHK--VNFSPPGDT--NSLFPGTW---------YLERVDE 497 R +S EE+ +++ YH V F T LFPG W L+ + E Sbjct: 382 DRYSLSMEEYEQLL------YHSSAVAFGTRNVTLDYQLFPGVWKKIAGKGRLVLKAIKE 435 Query: 498 QHRR 501 HR+ Sbjct: 436 FHRK 439 >4YXV-A nrPDB Length = 420 Score = 87.4 bits (215), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 99/419 (23%), Positives = 171/419 (40%), Gaps = 69/419 (16%) Query: 55 GILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLM 114 GI A+ V+ Y+D +L KY +++ ++ L + + ED + + + ++ Sbjct: 5 GIEAMNVFGGTAYLDVMELAKYRHLDTARFENLLMKEK-AVALPYEDPVTFGVNAAKPII 63 Query: 115 ERI-QLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASL 173 + + + D + L +E+ ID K++ T + E + N + + A Y GTA Sbjct: 64 DALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLNRNCRL--FEVKQAAYSGTAGF 121 Query: 174 FNAANWMESSSWDGRYAMVVCGDIA---VYPSGN--------ARPTGGAGAVAMLIGPKA 222 A N++ S + G A+V+ DI+ + G+ A P+ GAGAVA+L+G Sbjct: 122 QMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSEDWSYAEPSAGAGAVAVLVGENP 181 Query: 223 PL-ALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQW 281 + ++ G G + V D +P SE D LS+ YL ++ + Y+K++ Sbjct: 182 EVFQIDPGANGYYGYEVMDTCRPIPDSEAG--DSDLSLMSYLDCCEQTFLEYQKRVPGAN 239 Query: 282 KQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGL 341 Q D QY+ +HTPF MV+ + +M Sbjct: 240 YQ---------DTFQYLAYHTPFGGMVKGAHRTMM------------------------- 265 Query: 342 KLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQE 401 + + K + F + K L GN+ ++L+ LAS + Sbjct: 266 --------RKVAKVKTSGIETDFLTRVKPGLNYCQRVGNIMGAALFLALASTIDQGRFD- 316 Query: 402 LAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEF 460 RIG FSYGSG + F+S +P + T + K L R +S EE+ Sbjct: 317 -TPKRIGCFSYGSGCCSEFYS-------GITTPQGQERQRTFGIEKHLDRRYQLSMEEY 367 >3LEH-A nrPDB Length = 425 Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 104/443 (23%), Positives = 171/443 (38%), Gaps = 70/443 (15%) Query: 65 AQYV-DQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERIQLPWDS 123 +QYV + DL + + K++ GL + + +D+ +L ++ + Sbjct: 47 SQYVLNMKDLAEARGEDPQKFSKGLLLNALSIAPITDDVVTLAAGSANEIL--TAEDKEK 104 Query: 124 VGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESS 183 + + + TE+ +D+SKA + L + ACY TA+L N A Sbjct: 105 IDMVILATESSVDQSKAGAVYVHSLL--GIQPFARSFEMKEACYSATAAL-NYAKLHVEK 161 Query: 184 SWDGRYAMVVCGDIAVYPSGN-ARPTGGAGAVAMLIGPKAPLALERGLRGTHMENVYDFY 242 D R +V+ DIA Y G T GAG++AML+ + + ++ DF+ Sbjct: 162 HPDTR-VLVLASDIAKYGIGTPGESTQGAGSIAMLVKKDPRILILHDETLAQTRDIMDFW 220 Query: 243 KPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHT 302 +PN + P V+G S + YL L + Y+K+ +L D FH Sbjct: 221 RPNYTTT-PYVNGMYSTKQYLDMLKTTWAEYQKRFD-----------VSLTDFAAFCFHL 268 Query: 303 PFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKASQD 362 PF K+ K NK +DK + Q+ Sbjct: 269 PFPKLALKGF------------------------------------NKIMDKQVPSDLQE 292 Query: 363 MFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASFFS 422 +AS+ S GN+YT SL+ L +S +AG +I FSYGSG A F+ Sbjct: 293 KLKVNFEASILYSKQIGNIYTGSLF-LGLLSLLENSQNLVAGDKIALFSYGSGAVAEIFT 351 Query: 423 FRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDT 482 + + ++L +L R +S E + +I + Q K N S Sbjct: 352 GTLVKGFKEQLQTNRL--------DKLKRRTPLSVENYEKIFFEEAQLDDKGNAS----F 399 Query: 483 NSLFPGTWYLERVDEQHRRKYAR 505 G + L+ + E H+R Y + Sbjct: 400 KEYQTGPFALKEILE-HQRIYGK 421 >6ESQ-I nrPDB Length = 349 Score = 58.2 bits (139), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 90/380 (23%), Positives = 145/380 (38%), Gaps = 72/380 (18%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 KD+GI+ Y P + ++ K + GL S ED ++ + + Sbjct: 2 KDIGIVGYGSYIPKYRIKVEEIAKVWGKDPEAIKKGLVVNEKSVPSPDEDTATIAVEAAR 61 Query: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNT-DIEGIDTTNACYGGT 170 ++R + + +G + VG+E+ AVK + + G T D+ D AC GT Sbjct: 62 NAVKRAGINAEKIGAVYVGSES---HPYAVKPTSATVAEAIGATPDLTAADLEFACKAGT 118 Query: 171 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNA-RPTGGAGAVAMLIGPKAP--LALE 227 A + + S + Y M + D A G+A T AG A +IG K +A+ Sbjct: 119 AGIQMCMGLVGSGLIE--YGMAIGADTAQGAPGDALEYTASAGGAAYIIGNKKDEMIAVF 176 Query: 228 RGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSD 287 G ++ + DF++ S YP G+ + + +Y K + N K Sbjct: 177 NGTY-SYTTDTPDFWRREGQS-YPKHGGRFTGE----------PAYFKHVLNAAKGIMEK 224 Query: 288 RPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTY 347 T+ D Y +FH P K K+ L F Sbjct: 225 MGTTVKDYDYCVFHQPNGKFYIKAAKSLGF------------------------------ 254 Query: 348 TNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRI 407 TN+ LL + YL GN Y+ ++ L+++L H A+E G+RI Sbjct: 255 TNEQYKYGLL-------------TPYL----GNTYSGAVPLGLSNILDH--AEE--GARI 293 Query: 408 GAFSYGSGLAASFFSFRVSQ 427 A SYGSG + F V++ Sbjct: 294 LAVSYGSGAGSDAFDITVTE 313 >4YLT-A nrPDB Length = 316 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 46/200 (23%), Positives = 80/200 (40%), Gaps = 14/200 (7%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 IL Y P Q DLEK + G + E + ++ ++ +E Sbjct: 5 ILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALE 64 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + D +G + V T + S A + ++ + G D D AC G T +L Sbjct: 65 MAGIDKDDIGLIIVATTS---SSHAFPSSACQVQRMLGIKDAASFDLAAACAGFTYALSV 121 Query: 176 AANWMESSSWDGRYAMVVCGDI---AVYPSGNARPT-GGAGAVAMLIGPKAPLALERGLR 231 A +++S + ++A+V+ D+ A+ P G GA A+++G + G+ Sbjct: 122 ADQYVKSGAV--KHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGASE----QPGIM 175 Query: 232 GTHMENVYDFYKPNLASEYP 251 TH+ + Y LA YP Sbjct: 176 STHL-HADGRYGELLALPYP 194 >3ZU2-A nrPDB Length = 422 Score = 33.5 bits (75), Expect = 0.21, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 231 RGTH---MENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSD 287 +GTH +E VY YK +L + P +D + ++ + LD + ++Q W Q +D Sbjct: 322 KGTHEGCIEQVYSLYKDSLCGDSPHMDQEGRLRADYKELD---PEVQNQVQQLWDQVTND 378 Query: 288 RPFTLDDL 295 + L D Sbjct: 379 NIYQLTDF 386 >5AQB-A nrPDB Length = 428 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 39/169 (23%), Positives = 64/169 (37%), Gaps = 20/169 (11%) Query: 337 AFGGLKLEDTYTNKDLDKALLKASQDMF--DKKTKASLYLSTHNGNMYTSSLYGCLASLL 394 F L L + + ++ + LLK D+ DK K L+ NGN + + G A+L+ Sbjct: 112 GFTPLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLV 171 Query: 395 SHHSAQELAGSRIGAFSYGSGLAASFFSFRVSQDAAP----------GSPLDKLVSSTSD 444 A + G+R+G SFR S++ P G+ L ++ + Sbjct: 172 KVKDAADQLGARVGYIELDLNSGKILESFR-SEERFPMMSTFKVLLAGAILSRIDAGQEQ 230 Query: 445 LPKR-------LASRKCVSPEEFTEIMNQREQFYHKVNFSPPGDTNSLF 486 L +R L V+ + T+ M RE + S N L Sbjct: 231 LGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLL 279 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2WYA-A nrPDB 651 0.0 2P8U-A nrPDB 615 e-176 2FA3-A nrPDB 560 e-160 5HWO-A nrPDB 422 e-118 5KP5-A nrPDB 414 e-116 4YXV-A nrPDB 399 e-111 3LEH-A nrPDB 378 e-105 1YSL-B nrPDB 374 e-104 1XPM-A nrPDB 346 1e-95 6ESQ-I nrPDB 284 6e-77 Sequences not found previously or not previously below threshold: 5BNS-A nrPDB 84 2e-16 4YLT-A nrPDB 76 4e-14 3IL7-A nrPDB 70 2e-12 4NHD-A nrPDB 70 2e-12 1MZJ-A nrPDB 69 5e-12 5BQS-A nrPDB 62 4e-10 3H76-A nrPDB 59 6e-09 2AJ9-A nrPDB 58 9e-09 3IL4-A nrPDB 56 2e-08 4RYB-A nrPDB 55 7e-08 3WD7-A nrPDB 52 5e-07 4YJY-A nrPDB 52 7e-07 1QLV-A nrPDB 51 9e-07 1UB7-A nrPDB 51 1e-06 5WX5-A nrPDB 50 2e-06 3LED-A nrPDB 49 5e-06 6DXD-A nrPDB 48 8e-06 3A5R-A nrPDB 48 1e-05 4X0O-A nrPDB 47 2e-05 2P0U-A nrPDB 47 2e-05 6ET0-A nrPDB 43 3e-04 3OIT-A nrPDB 34 0.15 2TLD-E nrPDB 32 0.81 3V7I-A nrPDB 29 5.4 >2WYA-A nrPDB Length = 460 Score = 651 bits (1680), Expect = 0.0, Method: Composition-based stats. Identities = 458/458 (100%), Positives = 458/458 (100%) Query: 51 PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVV 110 PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVV Sbjct: 3 PKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVV 62 Query: 111 QRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT 170 QRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT Sbjct: 63 QRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT 122 Query: 171 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGL 230 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGL Sbjct: 123 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGL 182 Query: 231 RGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF 290 RGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF Sbjct: 183 RGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF 242 Query: 291 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK 350 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK Sbjct: 243 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK 302 Query: 351 DLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAF 410 DLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAF Sbjct: 303 DLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAF 362 Query: 411 SYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQF 470 SYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQF Sbjct: 363 SYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQF 422 Query: 471 YHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV 508 YHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV Sbjct: 423 YHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRPV 460 >2P8U-A nrPDB Length = 478 Score = 615 bits (1585), Expect = e-176, Method: Composition-based stats. Identities = 310/455 (68%), Positives = 380/455 (83%) Query: 53 DVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQR 112 DVGI+ALE+YFP+QYVDQ +LEKY+ V+AGKYT+GLGQ +MGFC+ +EDINSLC+TVVQ Sbjct: 24 DVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCTDREDINSLCMTVVQN 83 Query: 113 LMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTAS 172 LMER L +D +GRLEVGTETIIDKSK+VKT LM+LF++SGNTDIEGIDTTNACYGGTA+ Sbjct: 84 LMERNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAA 143 Query: 173 LFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRG 232 +FNA NW+ESSSWDGRYA+VV GDIAVY +GNARPTGG GAVA+LIGP APL ERGLRG Sbjct: 144 VFNAVNWIESSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGPNAPLIFERGLRG 203 Query: 233 THMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTL 292 THM++ YDFYKP++ SEYPIVDGKLSIQCYL ALDRCY+ Y KKI QW++ G+D+ FTL Sbjct: 204 THMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYCKKIHAQWQKEGNDKDFTL 263 Query: 293 DDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDL 352 +D +MIFH+P+CK+VQKSLAR++ NDFL+ + + S+Y GLEAFG +KLEDTY ++D+ Sbjct: 264 NDFGFMIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEAFGDVKLEDTYFDRDV 323 Query: 353 DKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSY 412 +KA +KAS ++F +KTKASL +S NGNMYTSS+YG LAS+L+ +S Q+LAG RIG FSY Sbjct: 324 EKAFMKASSELFSQKTKASLLVSNQNGNMYTSSVYGSLASVLAQYSPQQLAGKRIGVFSY 383 Query: 413 GSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYH 472 GSGLAA+ +S +V+QDA PGS LDK+ +S DL RL SR V+P+ F E M RE +H Sbjct: 384 GSGLAATLYSLKVTQDATPGSALDKITASLCDLKSRLDSRTGVAPDVFAENMKLREDTHH 443 Query: 473 KVNFSPPGDTNSLFPGTWYLERVDEQHRRKYARRP 507 VN+ P G +SLF GTWYL RVDE+HRR YARRP Sbjct: 444 LVNYIPQGSIDSLFEGTWYLVRVDEKHRRTYARRP 478 >2FA3-A nrPDB Length = 450 Score = 560 bits (1442), Expect = e-160, Method: Composition-based stats. Identities = 215/457 (47%), Positives = 306/457 (66%), Gaps = 10/457 (2%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 K+VGILA+++YFP V Q LE ++ GKYT+GLGQ + FC+ ED+ S+ V Sbjct: 2 KNVGILAMDIYFPPTCVQQEALEAHDGASKGKYTIGLGQDCLAFCTELEDVISMSFNAVT 61 Query: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 L+E+ ++ +GRLEVG+ET+IDKSK++KT LM+LF+ GNTD+EG+D+TNACYGGTA Sbjct: 62 SLLEKYKIDPKQIGRLEVGSETVIDKSKSIKTFLMQLFEKCGNTDVEGVDSTNACYGGTA 121 Query: 172 SLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLR 231 +L N NW+ES+SWDGRY +V+C D AVY G ARPTGGA A+AMLIGP AP+ E LR Sbjct: 122 ALLNCVNWVESNSWDGRYGLVICTDSAVYAEGPARPTGGAAAIAMLIGPDAPIVFESKLR 181 Query: 232 GTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFT 291 G+HM +VYDFYKPNLASEYP+VDGKLS CYL ALD CY K + N++++ + F+ Sbjct: 182 GSHMAHVYDFYKPNLASEYPVVDGKLSQTCYLMALDSCY----KHLCNKFEKL-EGKEFS 236 Query: 292 LDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKD 351 ++D Y +FH+P+ K+VQKS ARL++NDFL +S + + + L L+++Y ++D Sbjct: 237 INDADYFVFHSPYNKLVQKSFARLLYNDFLRNASSIDEAAKEKFTPYSSLSLDESYQSRD 296 Query: 352 LDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS 411 L+K + ++ +D K + + + GNMYT+SLY ASL+ H+ +LAG R+ FS Sbjct: 297 LEKVSQQLAKTYYDAKVQPTTLVPKQVGNMYTASLYAAFASLV-HNKHSDLAGKRVVMFS 355 Query: 412 YGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFY 471 YGSG A+ FS R+ ++ +P S + ++S D+ +L +R +PE+F E M E Y Sbjct: 356 YGSGSTATMFSLRLCENQSPFSLSN--IASVMDVGGKLKARHEYAPEKFVETMKLMEHRY 413 Query: 472 HKVNF--SPPGDTNSLFPGTWYLERVDEQHRRKYARR 506 F S G + L PGT+YL+ VD +RR Y ++ Sbjct: 414 GAKEFVTSKEGILDLLAPGTYYLKEVDSLYRRFYGKK 450 >5HWO-A nrPDB Length = 420 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 167/456 (36%), Positives = 226/456 (49%), Gaps = 44/456 (9%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 K VGI AL V P++YVD DL + V+ KYT GLG M ED +L T Sbjct: 5 KRVGIEALAVAVPSRYVDIEDLARARGVDPAKYTAGLGAREMAVTDPGEDTVALAATAAA 64 Query: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTA 171 RL+ + + +G L VGTET ID SK V + + L + + DT +ACYGGTA Sbjct: 65 RLIRQQDVDPSRIGMLVVGTETGIDHSKPVASHVQGLLKLPR--TMRTYDTQHACYGGTA 122 Query: 172 SLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNA-RPTGGAGAVAMLIGPKAP-LALERG 229 L A W+ S + G+ A+VVC DIA Y A PT G GAVA+L+ + LA++ G Sbjct: 123 GLMAAVEWIASGAGAGKVAVVVCSDIARYGLNTAGEPTQGGGAVALLVSEQPDLLAMDVG 182 Query: 230 LRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRP 289 L G +VYDF++P + +VDG SI CYL AL Y +R+K SD Sbjct: 183 LNGVCSMDVYDFWRP-VGRREALVDGHYSITCYLEALSGAYRGWREKALAAGLVRWSD-A 240 Query: 290 FTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTN 349 + L + +H PFCKM +K+ +L D L ++D S + EA Sbjct: 241 LPGEQLARIAYHVPFCKMARKAHTQLRLCD-LEDAADAAASTPESREA------------ 287 Query: 350 KDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGA 409 S +D + SL L++ GN+YT+SLY LA LL H A LAG RIG Sbjct: 288 -------QAKSAASYDAQVATSLGLNSRIGNVYTASLYLALAGLL-QHEAGALAGQRIGL 339 Query: 410 FSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQ 469 SYGSG AA F+S V + AA + +DL LA R+ VS EE+ +M Sbjct: 340 LSYGSGCAAEFYSGTVGEKAAE-------RMAKADLEAVLARRERVSIEEYERLM----- 387 Query: 470 FYHKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYAR 505 K+ P + + PG + L + + HRR+YA Sbjct: 388 ---KLPADAP-EAVAPSPGAFRLTEIRD-HRRQYAE 418 >5KP5-A nrPDB Length = 443 Score = 414 bits (1063), Expect = e-116, Method: Composition-based stats. Identities = 114/474 (24%), Positives = 191/474 (40%), Gaps = 84/474 (17%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 + VGI AL VY A ++ L + ++ ++ L ED S + + Sbjct: 26 QQVGIEALSVYGGAAQLELRKLAQARQLDISRFDN-LMMKEKAVSLPYEDPVSYAVNAAK 84 Query: 112 RLMERI-QLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGT 170 +++R+ + + +E+ ID K++ T + E S N + + ACY GT Sbjct: 85 PIIDRLSDADKQRIEMVITCSESGIDFGKSMSTYIQEYLGLSRNCRM--FELKQACYSGT 142 Query: 171 ASLFNAANWMESSSWDGRYAMVVCGDIAVY--PSGN---------ARPTGGAGAVAMLIG 219 A L A N + S ++ G A+V+ DI+ + G A P+ GAGAVA+L+ Sbjct: 143 AGLQMAINLILSQTFPGAKALVIATDISRFLVAEGGEAINYDWSFAEPSSGAGAVALLVS 202 Query: 220 PKAPL-ALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQ 278 + ++ G G + V D +PN SE D LS+ YL + Y Y+ +++ Sbjct: 203 DTPHIFQIDVGCNGYYGYEVMDTCRPNPDSEAG--DADLSLLSYLDCCENAYRHYQNRVE 260 Query: 279 NQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAF 338 G D + Y+ FHTPF MV+ + +M Sbjct: 261 ------GVDYRES---FDYLSFHTPFGGMVKGAHRNMM---------------------- 289 Query: 339 GGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHS 398 + L +A + F ++ L GN+ ++L+ LAS + + Sbjct: 290 -----------RRLKRAKPAEIEADFQRRVMPGLVYCQQVGNIMGATLFLSLASTIDNGD 338 Query: 399 AQELAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPE 458 RIG FSYGSG + F+S V+ + A +++ + +LA R +S E Sbjct: 339 FS--TPRRIGMFSYGSGCCSEFYSGVVTPEGAA-------IAAQQGISAQLADRYSLSME 389 Query: 459 EFTEIMNQREQFYHKVNFSPPGDT--NSLFPGTW---------YLERVDEQHRR 501 E+ +++ V F T LFPG W L+ + E HR+ Sbjct: 390 EYEQLLYHSS----AVAFGTRNVTLDYQLFPGVWKKIAGKGRLVLKAIKEFHRK 439 >4YXV-A nrPDB Length = 420 Score = 399 bits (1025), Expect = e-111, Method: Composition-based stats. Identities = 108/471 (22%), Positives = 184/471 (39%), Gaps = 84/471 (17%) Query: 55 GILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLM 114 GI A+ V+ Y+D +L KY +++ ++ L + ED + + + ++ Sbjct: 5 GIEAMNVFGGTAYLDVMELAKYRHLDTARFENLLMK-EKAVALPYEDPVTFGVNAAKPII 63 Query: 115 ERI-QLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASL 173 + + + D + L +E+ ID K++ T + E + N + + A Y GTA Sbjct: 64 DALSEAEKDRIELLITCSESGIDFGKSLSTYIHEYLGLNRNCRL--FEVKQAAYSGTAGF 121 Query: 174 FNAANWMESSSWDGRYAMVVCGDIAVY---PSGN--------ARPTGGAGAVAMLIGPKA 222 A N++ S + G A+V+ DI+ + G+ A P+ GAGAVA+L+G Sbjct: 122 QMAVNFILSQTSPGAKALVIASDISRFLIAEGGDALSEDWSYAEPSAGAGAVAVLVGENP 181 Query: 223 PL-ALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQW 281 + ++ G G + V D +P SE D LS+ YL ++ + Y+K++ Sbjct: 182 EVFQIDPGANGYYGYEVMDTCRPIPDSEAG--DSDLSLMSYLDCCEQTFLEYQKRVPGAN 239 Query: 282 KQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGL 341 Q D QY+ +HTPF MV+ + +M Sbjct: 240 YQ---------DTFQYLAYHTPFGGMVKGAHRTMM------------------------- 265 Query: 342 KLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQE 401 + + K + F + K L GN+ ++L+ LAS + Sbjct: 266 --------RKVAKVKTSGIETDFLTRVKPGLNYCQRVGNIMGAALFLALASTIDQGRFD- 316 Query: 402 LAGSRIGAFSYGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFT 461 RIG FSYGSG + F+S +P + T + K L R +S EE+ Sbjct: 317 -TPKRIGCFSYGSGCCSEFYSG-------ITTPQGQERQRTFGIEKHLDRRYQLSMEEYE 368 Query: 462 EIMNQREQFYHKVNFSPPGDT--NSLFPGT---------WYLERVDEQHRR 501 + V F + PG +LE + E HR+ Sbjct: 369 LLFKGS----GMVRFGTRNVKLDFEMIPGIMQSTQEKPRLFLEEISEFHRK 415 >3LEH-A nrPDB Length = 425 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 106/454 (23%), Positives = 175/454 (38%), Gaps = 69/454 (15%) Query: 53 DVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQR 112 +GI + ++ DL + + K++ GL + + +D+ +L Sbjct: 36 RIGIDKIGFTSSQYVLNMKDLAEARGEDPQKFSKGLLLNALSIAPITDDVVTLAAGSANE 95 Query: 113 LMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTAS 172 ++ + + + + TE+ +D+SKA + L + ACY TA+ Sbjct: 96 IL--TAEDKEKIDMVILATESSVDQSKAGAVYVHSLLG--IQPFARSFEMKEACYSATAA 151 Query: 173 LFNAANWMESSSWDGRYAMVVCGDIAVYPSG-NARPTGGAGAVAMLIGPKAPLALERGLR 231 L N A D R +V+ DIA Y G T GAG++AML+ + + Sbjct: 152 L-NYAKLHVEKHPDTR-VLVLASDIAKYGIGTPGESTQGAGSIAMLVKKDPRILILHDET 209 Query: 232 GTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFT 291 ++ DF++PN + P V+G S + YL L + Y+K+ + Sbjct: 210 LAQTRDIMDFWRPNYTTT-PYVNGMYSTKQYLDMLKTTWAEYQKRF-----------DVS 257 Query: 292 LDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKD 351 L D FH PF K+ K NK Sbjct: 258 LTDFAAFCFHLPFPKLALKGF------------------------------------NKI 281 Query: 352 LDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFS 411 +DK + Q+ +AS+ S GN+YT SL+ L SLL + S +AG +I FS Sbjct: 282 MDKQVPSDLQEKLKVNFEASILYSKQIGNIYTGSLFLGLLSLLEN-SQNLVAGDKIALFS 340 Query: 412 YGSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFY 471 YGSG A F+ + + ++L +L R +S E + +I + Q Sbjct: 341 YGSGAVAEIFTGTLVKGFKEQLQTNRL--------DKLKRRTPLSVENYEKIFFEEAQLD 392 Query: 472 HKVNFSPPGDTNSLFPGTWYLERVDEQHRRKYAR 505 K N S G + L+ + E H+R Y + Sbjct: 393 DKGNAS----FKEYQTGPFALKEILE-HQRIYGK 421 >1YSL-B nrPDB Length = 402 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 110/419 (26%), Positives = 183/419 (43%), Gaps = 64/419 (15%) Query: 54 VGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRL 113 +GI + + P Y+D T L + NV+ GK+ +G+GQ +M + +DI + + + Sbjct: 22 IGIDKISFFVPPYYIDMTALAEARNVDPGKFHIGIGQDQMAVNPISQDIVTFAANAAEAI 81 Query: 114 MERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASL 173 + + +++ + VGTE+ ID+SKA VL L + ACYG TA L Sbjct: 82 LTK--EDKEAIDMVIVGTESSIDESKAAAVVLHRLM--GIQPFARSFEIKEACYGATAGL 137 Query: 174 FNAANWMESSSWDGRYAMVVCGDIAVYP-SGNARPTGGAGAVAMLIGPKAPLALERGLRG 232 A N + + + +VV DIA Y + PT GAGAVAML+ + + + Sbjct: 138 QLAKNHV--ALHPDKKVLVVAADIAKYGLNSGGEPTQGAGAVAMLVASEPRILALKEDNV 195 Query: 233 THMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTL 292 +++YDF++P YP+VDG LS + Y+++ + + ++K+ Sbjct: 196 MLTQDIYDFWRPT-GHPYPMVDGPLSNETYIQSFAQVWDEHKKR-----------TGLDF 243 Query: 293 DDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDL 352 D + FH P+ KM +K+L L+ SD Sbjct: 244 ADYDALAFHIPYTKMGKKAL--------LAKISD-------------------------- 269 Query: 353 DKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSY 412 +A Q+ + + S+ S GN+YT SLY L SLL + + AG++IG FSY Sbjct: 270 ---QTEAEQERILARYEESIIYSRRVGNLYTGSLYLGLISLLENATTLT-AGNQIGLFSY 325 Query: 413 GSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFY 471 GSG A FF+ + + ++ L +R +S E+ + + Sbjct: 326 GSGAVAEFFTGELVAGYQNHLQKETHLAL-------LDNRTELSIAEYEAMFAETLDTD 377 >1XPM-A nrPDB Length = 396 Score = 346 bits (887), Expect = 1e-95, Method: Composition-based stats. Identities = 116/452 (25%), Positives = 179/452 (39%), Gaps = 73/452 (16%) Query: 54 VGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRL 113 +GI + Y P YVD L + V+ K+ +G+GQT M V +DI S+ + + Sbjct: 3 IGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAKDI 62 Query: 114 MERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASL 173 + +G + V TE+ +D +KA + L + ACY T ++ Sbjct: 63 I--TDEDKKKIGMVIVATESAVDAAKAAAVQIHNLL--GIQPFARCFEMKEACYAATPAI 118 Query: 174 FNAANWMESSSWDGRYAMVVCGDIAVYP-SGNARPTGGAGAVAMLIGPKAPLALERGLRG 232 A +++ ++ +V+ D A Y + PT GAGAVAM+I + Sbjct: 119 QLAKDYL--ATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSILALNEDAV 176 Query: 233 THMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTL 292 + E+VYDF++P +YP+VDG LS Y+R+ + + Y K+ + +L Sbjct: 177 AYTEDVYDFWRPT-GHKYPLVDGALSKDAYIRSFQQSWNEYAKR-----------QGKSL 224 Query: 293 DDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDL 352 D + FH PF KM +K+L ++ N A TQ L G E Sbjct: 225 ADFASLCFHVPFTKMGKKALESIIDN----ADETTQERLRSGYEDAVD------------ 268 Query: 353 DKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSY 412 + + GN+YT SLY L SLL + Q AG IG FSY Sbjct: 269 ---------------------YNRYVGNIYTGSLYLSLISLLENRDLQ--AGETIGLFSY 305 Query: 413 GSGLAASFFSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYH 472 GSG F+S + + + L +R VS + + + Sbjct: 306 GSGSVGEFYSATLVEGYKDHL-------DQAAHKALLNNRTEVSVDAYETFFK----RFD 354 Query: 473 KVNFSPPGDTNSLFPGTWYLERV----DEQHR 500 V F D +YL + E HR Sbjct: 355 DVEFDEEQDAVHEDRHIFYLSNIENNVREYHR 386 >6ESQ-I nrPDB Length = 349 Score = 284 bits (726), Expect = 6e-77, Method: Composition-based stats. Identities = 84/384 (21%), Positives = 139/384 (36%), Gaps = 72/384 (18%) Query: 52 KDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQ 111 KD+GI+ Y P + ++ K + GL S ED ++ + + Sbjct: 2 KDIGIVGYGSYIPKYRIKVEEIAKVWGKDPEAIKKGLVVNEKSVPSPDEDTATIAVEAAR 61 Query: 112 RLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGN-TDIEGIDTTNACYGGT 170 ++R + + +G + VG+E+ AVK + + G D+ D AC GT Sbjct: 62 NAVKRAGINAEKIGAVYVGSES---HPYAVKPTSATVAEAIGATPDLTAADLEFACKAGT 118 Query: 171 ASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNA-RPTGGAGAVAMLIGPKAP--LALE 227 A + + S + Y M + D A G+A T AG A +IG K +A+ Sbjct: 119 AGIQMCMGLVGSGLIE--YGMAIGADTAQGAPGDALEYTASAGGAAYIIGNKKDEMIAVF 176 Query: 228 RGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSD 287 G ++ + DF++ S YP G+ + + +Y K + N K Sbjct: 177 NGTY-SYTTDTPDFWRREGQS-YPKHGGRFTGE----------PAYFKHVLNAAKGIMEK 224 Query: 288 RPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTY 347 T+ D Y +FH P K K+ L F Sbjct: 225 MGTTVKDYDYCVFHQPNGKFYIKAAKSLGF------------------------------ 254 Query: 348 TNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRI 407 TN+ L+ + GN Y+ ++ L+++L H G+RI Sbjct: 255 TNEQYKYG-----------------LLTPYLGNTYSGAVPLGLSNILDHAE----EGARI 293 Query: 408 GAFSYGSGLAASFFSFRVSQDAAP 431 A SYGSG + F V++ Sbjct: 294 LAVSYGSGAGSDAFDITVTERIKE 317 >5BNS-A nrPDB Length = 317 Score = 83.8 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 39/188 (20%), Positives = 67/188 (35%), Gaps = 12/188 (6%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 I+ Y P Q DLEK + G + E ++++ R +E Sbjct: 5 IIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAATRAIE 64 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + D +G + V T + + + + G D AC G T +L Sbjct: 65 MAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCP---AFDVAAACAGFTYALSV 121 Query: 176 AANWMESSSWDGRYAMVVCGDI-AVYPSGNARPT-----GGAGAVAMLIGPKAPLALER- 228 A +++S + +YA+VV D+ A R T GAGA + + + Sbjct: 122 ADQYVKSGAV--KYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHL 179 Query: 229 GLRGTHME 236 G++ E Sbjct: 180 HADGSYGE 187 >4YLT-A nrPDB Length = 316 Score = 75.7 bits (184), Expect = 4e-14, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 64/176 (36%), Gaps = 11/176 (6%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 IL Y P Q DLEK + G + E + ++ ++ +E Sbjct: 5 ILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGLDETVATMGFQAAEKALE 64 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + D +G + V T + + + + D D AC G T +L Sbjct: 65 MAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGI---KDAASFDLAAACAGFTYALSV 121 Query: 176 AANWMESSSWDGRYAMVVCGDI-AVYPSGNARPT-----GGAGAVAMLIGPKAPLA 225 A +++S + ++A+V+ D+ + R T GAGAV + + + Sbjct: 122 ADQYVKSGAV--KHAIVIGSDVLSRALDPEDRGTIILFGDGAGAVVLGASEQPGIM 175 >3IL7-A nrPDB Length = 313 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 54/328 (16%), Positives = 110/328 (33%), Gaps = 35/328 (10%) Query: 53 DVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQR 112 +VGI Y P + +D E++ + + G + +D + L + Sbjct: 2 NVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASVK 61 Query: 113 LMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTAS 172 + + + + + V T T V +L E + +D AC G S Sbjct: 62 AIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTG---KVASMDQLAACSGFMYS 118 Query: 173 LFNAANWMESSSWDGRYAMVVCGD-IAVYPSGNARPTG---GAGAVAMLIGPKAP----L 224 + A +++S D +VV D ++ R T G GA A++IG + + Sbjct: 119 MITAKQYVQSG--DYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSEGRGII 176 Query: 225 ALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQA 284 + E G GT +++Y + + ++G+ + + + + + Sbjct: 177 SYEMGSDGTGGKHLY----LDKDTGKLKMNGR-----------EVFKFAVRIMGDASTRV 221 Query: 285 GSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLE 344 T DD+ I H ++++ + RL S + S+ Sbjct: 222 VEKANLTSDDIDLFIPHQANIRIMESARERLG-------ISKDKMSVSVNKYGNTSAASI 274 Query: 345 DTYTNKDLDKALLKASQDMFDKKTKASL 372 +++L LK + L Sbjct: 275 PLSIDQELKNGKLKDDDTIVLVGFGGGL 302 >4NHD-A nrPDB Length = 319 Score = 69.9 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 54/176 (30%), Gaps = 11/176 (6%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 IL Y P+Q DLEK G + E + + Q + Sbjct: 8 ILGTGSYLPSQVRTNADLEKMVETSDEWIVARTGIRERRIAADNETVADMAFFAAQNAIN 67 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + + + V T + + + G D AC G +L Sbjct: 68 MAGIDKHDIDMIIVATTSASHTFPSAACQVQGKLGIKGCP---AFDLAAACSGFMYALSI 124 Query: 176 AANWMESSSWDGRYAMVVCGD-IAVYPSGNARPT-----GGAGAVAMLIGPKAPLA 225 A ++S ++ +V+ D ++ R T GAGAV + + + Sbjct: 125 ADQHVKSGM--CKHVLVIGADALSKTCDPTDRSTIILFGDGAGAVVVGASNEPGIL 178 >1MZJ-A nrPDB Length = 339 Score = 68.8 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 57/290 (19%), Positives = 108/290 (37%), Gaps = 32/290 (11%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 +L + Y P + V ++ + + G E I + + +R +E Sbjct: 14 VLGVGSYRPRREVSNKEVCTWIDSTEEWIETRTGIRSRRIAEPDETIQVMGVAASRRALE 73 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVL-MELFQDSGNTDIEGIDTTNACYGGTASLF 174 + + + V T T + + + EL G + G D + AC G +L Sbjct: 74 HAGVDPAEIDLVVVSTMTNFVHTPPLSVAIAHEL----GADNAGGFDLSAACAGFCHALS 129 Query: 175 NAANWMESSSWDGRYAMVVC----GDIAVYPSGNARPTGGAGAVAMLIGPK--APLA-LE 227 AA+ +ES R+ +VV D+ + G GA A ++GP + + Sbjct: 130 IAADAVESGG--SRHVLVVATERMTDVIDLADRSLSFLFGDGAGAAVVGPSDVPGIGPVV 187 Query: 228 RGLRGT-----HMENVYDFY--KPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQ 280 RG+ GT HM + +D Y P++ ++DGK R + + Sbjct: 188 RGIDGTGLGSLHMSSSWDQYVEDPSVGRPALVMDGK-----------RVFRWAVADVVPA 236 Query: 281 WKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTS 330 ++A T+ DL + H +++ + RL + + S D + + Sbjct: 237 AREALEVAGLTVGDLVAFVPHQANLRIIDVLVDRLGVPEHVVVSRDAEDT 286 >5BQS-A nrPDB Length = 323 Score = 62.2 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 47/268 (17%), Positives = 93/268 (34%), Gaps = 16/268 (5%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 I + Y P Q V DL + + + G + E + L V ++LM Sbjct: 5 ISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRHISR-TESTSDLATEVAKKLMA 63 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + + + + + T I + + + + G D T AC G +L Sbjct: 64 KAGITGKELDFIILAT---ITPDSMMPSTAARVQANIGANKAFAFDLTAACSGFVFALST 120 Query: 176 AANWMESSSWDGRYAMVVCGDI-AVYPSGNARPTG-----GAGAVAMLIGPKAPLALERG 229 A ++ S + + +V+ + + + R T GAG V + + E Sbjct: 121 AEKFIASGRF--QKGLVIGSETLSKAVDWSDRSTAVLFGDGAGGVLLEASEQEHFLAES- 177 Query: 230 LRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKK-IQNQWKQAGSDR 288 L + Y + P D + S +L+ R + + + KQ + Sbjct: 178 LNSDGSRSECLTYGHSGLHS-PFSDQE-SADSFLKMDGRTVFDFAIRDVAKSIKQTIDES 235 Query: 289 PFTLDDLQYMIFHTPFCKMVQKSLARLM 316 P + DL Y++ H +++ K ++ Sbjct: 236 PIEVTDLDYLLLHQANDRILDKMARKIG 263 >3H76-A nrPDB Length = 359 Score = 58.8 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 61/377 (16%), Positives = 109/377 (28%), Gaps = 76/377 (20%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 + L P + V DL N G ++ +++L + ++ +E Sbjct: 28 LAGLGFSLPKRQVSNHDLVGRINTSDEFIVERTGVRTRYHVEPEQAVSALMVPAARQAIE 87 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 L + + L V T + + ++ L I +D C G L Sbjct: 88 AAGLLPEDIDLLLVNTLSPDHHDPSQACLIQPLLGL---RHIPVLDIRAQCSGLLYGLQM 144 Query: 176 AANWMESSSWDGRYAMVVCGDI--------AVYPSGNARPTGGAGAVAMLIGPKAP---L 224 A + + R+ +VVCG++ + + GAGAV + G L Sbjct: 145 ARGQILAGL--ARHVLVVCGEVLSKRMDCSDRGRNLSILLGDGAGAVVVSAGESLEDGLL 202 Query: 225 ALERGLRGTH----MENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQ 280 L G G + M P E + +G +L + + + Sbjct: 203 DLRLGADGNYFDLLMTAAPGSASPTFLDENVLREG---GGEFLMRGRPMFEHASQTLVRI 259 Query: 281 WKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGG 340 + + TLDD+ ++I H P +++ +L A + Sbjct: 260 AGEMLAAHELTLDDIDHVICHQPNLRILDAVQEQLGIPQHKFAVTVD------------- 306 Query: 341 LKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQ 400 GNM ++S LA Sbjct: 307 ------------------------------------RLGNMASASTPVTLAMFW----PD 326 Query: 401 ELAGSRIGAFSYGSGLA 417 G R+ +YGSG Sbjct: 327 IQPGQRVLVLTYGSGAT 343 >2AJ9-A nrPDB Length = 356 Score = 58.0 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 61/376 (16%), Positives = 114/376 (30%), Gaps = 64/376 (17%) Query: 47 TDTWPKDVGILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLC 106 T + + VG+L++ Y P + V ++ ++ + G F + E S+ Sbjct: 27 TTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEAIYTRTGIKTRRFAADDESAASMA 86 Query: 107 LTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNAC 166 +R + L + + V T T ++ ++ G I G D + C Sbjct: 87 TEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGAKG---ILGFDLSAGC 143 Query: 167 YGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLAL 226 A YA+ D+ G GA ML+ L Sbjct: 144 ----AGF--------------GYALGAAADMIR----------GGGAATMLVVGTEKL-- 173 Query: 227 ERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGS 286 + ++YD + + DG ++ G Sbjct: 174 ------SPTIDMYD-----AGNCFIFADGAAAVVVGETPFQGIGP-------TVAGSDGE 215 Query: 287 DRPFTLDDLQYMIFHT------PFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGG 340 D+ ++ F PF ++ + A + F + G+ Sbjct: 216 QADAIRQDIDWITFAQNPSGPRPFVRL--EGPAVFRWAAFKMGDVGRRAMDAAGVRPDQI 273 Query: 341 LKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQ 400 N +++ L+K Q D + H GN +S+ +A LL+ +A+ Sbjct: 274 DVFVPHQANSRINELLVKNLQLRPDAVVANDI---EHTGNTSAASIPLAMAELLTTGAAK 330 Query: 401 ELAGSRIGAFSYGSGL 416 G YG+GL Sbjct: 331 P--GDLALLIGYGAGL 344 >3IL4-A nrPDB Length = 320 Score = 56.5 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 60/368 (16%), Positives = 110/368 (29%), Gaps = 67/368 (18%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 I Y P V L + + G + + QE+ + LC V ++L+E Sbjct: 6 ISCTSRYVPENCVTNHQLSEMMDTSDEWIHSRTGISERRIVT-QENTSDLCHQVAKQLLE 64 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + + + V T T +V + G T+ D + AC G +L Sbjct: 65 KSGKQASEIDFILVATVTPDFNMPSVACQVQ---GAIGATEAFAFDISAACSGFVYALSM 121 Query: 176 AANWMESSSWDGRYAMVVCGDI-AVYPSGNARPTG---GAGAVAMLI--GPKAPLALERG 229 A + S + +V+ G+ + R T G GA +LI E+ Sbjct: 122 AEKLVLSGRYQT--GLVIGGETFSKMLDWTDRSTAVLFGDGAAGVLIEAAETPHFLNEK- 178 Query: 230 LRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRP 289 L+A + +T+ Sbjct: 179 ---------------------------------LQADGQRWTA-------------LTSG 192 Query: 290 FTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTN 349 +T+++ + H K +Q + F+ + S SL L + + Sbjct: 193 YTINESPFYQGHKQASKTLQMEGRSI-FDFAIKDVSQNILSLVTDETVDYLLLHQASVRI 251 Query: 350 KDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGA 409 D K S++ F GN +S+ L + + + + R+ Sbjct: 252 IDKIARKTKISREKFLTNMD-------KYGNTSAASIPILLDEAVENGTLILGSQQRVVL 304 Query: 410 FSYGSGLA 417 +G GL Sbjct: 305 TGFGGGLT 312 >4RYB-A nrPDB Length = 320 Score = 55.3 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 45/271 (16%), Positives = 91/271 (33%), Gaps = 20/271 (7%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 I Y PA V DL + + T G + E + L +R ++ Sbjct: 6 ISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALD 65 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 L + + V T T + + T++ + + D C G +L Sbjct: 66 AAGLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGC--PAFDVQAVCAGFMYALTT 123 Query: 176 AANWMESSSWDGRYAMVVCGDI-AVYPSGNARPT-----GGAGAVAMLIGPKAPLALER- 228 A +++S + A+V+ + + N R T GAGAV + K + + Sbjct: 124 ANAYIKSGM--AKNALVIGAETFSRIVDWNDRTTCVLFGDGAGAVVLSAADKPGIIHSKL 181 Query: 229 GLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRA-LDRCYTSYRKKIQNQWKQAGSD 287 G +++ L I GK+S Y+ + K + + Sbjct: 182 KADGNYLK--------LLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEE 233 Query: 288 RPFTLDDLQYMIFHTPFCKMVQKSLARLMFN 318 +T + +++ H ++++ + L + Sbjct: 234 AGYTAAQIDWIVPHQANRRIIESTAKHLGLS 264 >3WD7-A nrPDB Length = 403 Score = 52.2 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 50/142 (35%), Gaps = 16/142 (11%) Query: 101 DINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGI 160 ++ L + ++ P ++ L T +D A L L N D++ + Sbjct: 113 EVPKLGKEAATKAIKEWGQPKSNITHLIFCTSAGVDMPGA-DYQLTRLIGL--NPDVKRM 169 Query: 161 DT-TNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTG---------- 209 CY G L A + E++ G +VVC + + T Sbjct: 170 MIYQQGCYAGATILRLAKDLAENN--KGSRVLVVCSENTIPTFRGPSYTHIDSLVGQALF 227 Query: 210 GAGAVAMLIGPKAPLALERGLR 231 GA A+++G ++ER L Sbjct: 228 ADGAAALIVGADPDTSIERPLY 249 >4YJY-A nrPDB Length = 398 Score = 51.8 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 37/174 (21%), Positives = 62/174 (35%), Gaps = 24/174 (13%) Query: 99 QEDIN-----SLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSG 153 ++DI L Q+ ++ P + L T + +D A L ++ Sbjct: 97 RQDIVVVEVPKLGKAAAQKAIKEWGQPRSRITHLVFCTTSGVDMPGA-DYQLAKMLGLRP 155 Query: 154 NTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDI-AVYPSGNARPTG--- 209 N + C+ G L A + E++ G + VC +I AV G + Sbjct: 156 NVS-RLMMYQQGCFAGGTVLRVAKDLAENNR--GARVLAVCSEITAVTFRGPSESHLDSM 212 Query: 210 ------GAGAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKL 257 G GA A+++G A+ER L M + P+ +DG L Sbjct: 213 VGQALFGDGAAAVIVGSDPDEAVERPL--FQMVSASQTILPD---SEGAIDGHL 261 >1QLV-A nrPDB Length = 402 Score = 51.5 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 48/270 (17%), Positives = 94/270 (34%), Gaps = 24/270 (8%) Query: 105 LCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTN 164 L + ++ LP + L T +D A L++L S + + Sbjct: 110 LGKEAAVKAIDEWGLPKSKITHLIFCTTAGVDMPGA-DYQLVKLLGLSPSVK-RYMLYQQ 167 Query: 165 ACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAV---YPSGN-------ARPTGGAGAV 214 C G L A + E++ G ++VC +I + A+ G GA Sbjct: 168 GCAAGGTVLRLAKDLAENN--KGSRVLIVCSEITAILFHGPNENHLDSLVAQALFGDGAA 225 Query: 215 AMLIGPKAPLALERGLRGTHMEN---VYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYT 271 A+++G LA+ER + + + D K + +G L+ Q + Sbjct: 226 ALIVGSGPHLAVERPIFEIVSTDQTILPDTEKAMKLH---LREGGLTFQLHRD----VPL 278 Query: 272 SYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSL 331 K I+N ++A S T + + + H ++ + +L + +S S Sbjct: 279 MVAKNIENAAEKALSPLGITDWNSVFWMVHPGGRAILDQVERKLNLKEDKLRASRHVLSE 338 Query: 332 YKGLEAFGGLKLEDTYTNKDLDKALLKASQ 361 Y L + L + D + + + + Sbjct: 339 YGNLISACVLFIIDEVRKRSMAEGKSTTGE 368 >1UB7-A nrPDB Length = 322 Score = 50.7 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 61/363 (16%), Positives = 102/363 (28%), Gaps = 54/363 (14%) Query: 55 GILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLM 114 GILAL Y P + + D E Y + G + E + L V+ L+ Sbjct: 3 GILALGAYVPERVMTNADFEAYLDTSDEWIVTRTGIKERRVAAEDEYTSDLAFKAVEDLL 62 Query: 115 ERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLF 174 R + V + V T T A+ L Q D C G +L Sbjct: 63 RRHPGALEGVDAVIVATNT----PDALFPDTAALVQARFGLKAFAYDLLAGCPGWIYALA 118 Query: 175 NAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTH 234 A +E+ + + V GA A++ +I Sbjct: 119 QAHALVEAGL--AQKVLAV----------------GAEALSKIIDWNDRATAVL------ 154 Query: 235 MENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDD 294 F A+ V + ++ D + ++ + Sbjct: 155 ------FGDGGGAAVVGKVREGYGFRSFVLGADGTGAKELYHACVAPR---LPDGTSMKN 205 Query: 295 LQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDK 354 YM + V K R+M L A GL N + Sbjct: 206 RLYM-----NGREVFKFAVRVMNTATLEAIE------KAGLTPEDIRLFVPHQANLRI-- 252 Query: 355 ALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGS 414 + A+++ + GN T+S+ L + +E G + S+G+ Sbjct: 253 --IDAARERLGLPWERVAVNVDRYGNTSTASIPLALKEAVDAGRIRE--GDHVLLVSFGA 308 Query: 415 GLA 417 GL Sbjct: 309 GLT 311 >5WX5-A nrPDB Length = 411 Score = 50.3 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 58/333 (17%), Positives = 112/333 (33%), Gaps = 65/333 (19%) Query: 100 EDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEG 159 E++ L + ++ P + L + +D A LM L + + Sbjct: 118 EEVPKLGKEAALKAIKEWGQPLSKITHLIFSAMSGVDIPGA-DFRLMNLLGLEPSVN-RL 175 Query: 160 IDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCG--DIAVYPSGN------ARPTGGA 211 + T CY G A++ +A + E+++ R +V C D+ + N + G Sbjct: 176 MIYTQGCYMGGAAMRHAKDIAENNAGA-RVLLVFCDLMDMYFHAPQNRVDLLVGQAVFGD 234 Query: 212 GAVAMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYT 271 GA A+++G D +E P+ + +R Sbjct: 235 GAAALIVGADPD----------------DDC-----TERPLF-------QVVSCAERAVP 266 Query: 272 SYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSL 331 + I+ K+ G + + D +M+ K++ +L+ + SL Sbjct: 267 GTQDYIKAHLKEMGMELHLSTD----------VPRMIGKNIEKLLADAVSPFGISDWNSL 316 Query: 332 YKGLEAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLA 391 + + L+ N L + L+AS+ Y+ + GNM +S++ L Sbjct: 317 FYIVHPGAVAILDQVEENLGLGEDKLRASR-----------YVLSEYGNMGAASVFFILD 365 Query: 392 SL----LSHHSAQELAGSRIG-AFSYGSGLAAS 419 + G G FS+G GL Sbjct: 366 EMRNKSAEEGKLTTGEGLEWGVLFSFGPGLTVE 398 >3LED-A nrPDB Length = 392 Score = 48.8 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 31/85 (36%), Gaps = 4/85 (4%) Query: 102 INSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGID 161 + + +T ++ +ER P + +G + + A+ + G D Sbjct: 117 LAEMAVTAAEQAIERWGKPRERIGAVLCACSNMQRAYPAMAIEVQNALGLGG----FAFD 172 Query: 162 TTNACYGGTASLFNAANWMESSSWD 186 AC T L AA+++ S D Sbjct: 173 MNVACSSATFGLKTAADFVGGGSVD 197 >6DXD-A nrPDB Length = 395 Score = 48.4 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 48/145 (33%), Gaps = 19/145 (13%) Query: 97 SVQEDIN-----SLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQD 151 ++DI L + ++ P + + T + +D A L +L Sbjct: 97 DTRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGA-DYQLTKLLGL 155 Query: 152 SGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVY---PSGN---- 204 + + C+ G L A + E++ G +VVC +I + Sbjct: 156 -RPSVKRLMMYQQGCFAGGTVLRIAKDLAENNR--GARVLVVCSEITAVTFRGPSDTHLD 212 Query: 205 ---ARPTGGAGAVAMLIGPKAPLAL 226 + GA A+++G ++ Sbjct: 213 SLVGQALFSDGAAALIVGSDPDTSV 237 >3A5R-A nrPDB Length = 387 Score = 47.6 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 65/182 (35%), Gaps = 22/182 (12%) Query: 60 EVYFPAQYVDQTD--LEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLMERI 117 +Y+ T+ L++ N+ A + T + +M V E L + ++ Sbjct: 58 NSRIEKRYLHVTEEILKENPNIAAYEATSLNVRHKMQVKGVAE----LGKEAALKAIKEW 113 Query: 118 QLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTN-ACYGGTASLFNA 176 P + L V +D A L +L + ++ + CY G L A Sbjct: 114 GQPKSKITHLIVCCLAGVDMPGA-DYQLTKLLDL--DPSVKRFMFYHLGCYAGGTVLRLA 170 Query: 177 ANWMESSSWDGRYAMVVCGDIAVY---PSGN-------ARPTGGAGAVAMLIGPKAPLAL 226 + E++ G ++VC ++ + G GA A+++G L + Sbjct: 171 KDIAENN--KGARVLIVCSEMTTTCFRGPSETHLDSMIGQAILGDGAAAVIVGADPDLTV 228 Query: 227 ER 228 ER Sbjct: 229 ER 230 >4X0O-A nrPDB Length = 362 Score = 47.2 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 42/322 (13%), Positives = 95/322 (29%), Gaps = 19/322 (5%) Query: 56 ILALEVYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTRMGFCSVQEDINSLCLTVVQRLME 115 I P + DL + + G + V + L Q + Sbjct: 8 ITGWGKCLPPATLSNHDLSTFLDTSDEWIQSRTGIEQRRISHVN--TSDLATVAAQHAIA 65 Query: 116 RIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFN 175 + + + + V T + + + + + D AC G L Sbjct: 66 CAGVSVEEIDLIIVATCSPDSLIPNIASRVQQNLGI---PSAAAFDLNAACTGFLYGLET 122 Query: 176 AANWMESSSWDGRYAMVVCGD-IAVYPSGNARPTG---GAGAVAMLIGPKAPLALERGLR 231 A M++S + R+A+V+ + ++ Y R T G GA A+++ + + Sbjct: 123 ATRLMQASHY--RHALVIGAERLSFYLDWTKRDTAVLFGDGAGAVVLSKTEQKVGLQDAQ 180 Query: 232 GTHMENVYDFYK-PNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPF 290 D P + D + + + + +Q + Sbjct: 181 IGCDAQGRDILAVPKFGTAMDRFDADNGYWAFDFVGKEIFKRAVRGMGAAAQQVLARSGL 240 Query: 291 TLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNK 350 + +++ +I H +++Q D L+ + + + + Sbjct: 241 STEEIDVVIPHQANIRIIQ------TLCD-LAGIAQDKAFVNIHRYGNTSAATVPIALCE 293 Query: 351 DLDKALLKASQDMFDKKTKASL 372 L++ +K D+ A L Sbjct: 294 ALEQGKIKPHDDLLVAAFGAGL 315 >2P0U-A nrPDB Length = 413 Score = 46.8 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 43/284 (15%), Positives = 89/284 (31%), Gaps = 23/284 (8%) Query: 105 LCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTN 164 L ++ P + + + T + ++ A + +L N + Sbjct: 123 LAKEASMNAIKEWGRPKSEITHIVMATTSGVNMPGA-ELATAKLLGLRPNVR-RVMMYQQ 180 Query: 165 ACYGGTASLFNAANWMESSSWDGRYAMVVCGD-IAVYPSGNARPTG---------GAGAV 214 C+ G L A + E+++ G + +C + AV + G GA Sbjct: 181 GCFAGATVLRVAKDLAENNA--GARVLAICSEVTAVTFRAPSETHIDGLVGSALFGDGAA 238 Query: 215 AMLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSY- 273 A+++G +ER + H L +DG L+ + L + Sbjct: 239 AVIVGSDPRPGIERPIYEMHWAGEM-----VLPESDGAIDGHLTEAGLVFHLLKDVPGLI 293 Query: 274 RKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYK 333 K I K + + + + H ++ + A+L +S S Y Sbjct: 294 TKNIGGFLKDTKNLVGASSWNELFWAVHPGGPAILDQVEAKLELEKGKFQASRDILSDYG 353 Query: 334 GLEAFGGLKLEDTYTNKDLDKALL---KASQDMFDKKTKASLYL 374 + + L + D + L+ + S+ F L + Sbjct: 354 NMSSASVLFVLDRVRERSLESNKSTFGEGSEWGFLIGFGPGLTV 397 >6ET0-A nrPDB Length = 365 Score = 43.0 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 39/240 (16%), Positives = 75/240 (31%), Gaps = 21/240 (8%) Query: 89 GQTRMGFCSVQ--EDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETII---------DK 137 G R G+ + E+ SL + +RL+ DSV L + I D Sbjct: 57 GVNRRGYFDPRNGENEFSLVVRAAERLLRSSDTAPDSVDMLICSASSPIMTDAGDVLPDL 116 Query: 138 SKAVKTVLMELF-QDSGNTDIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGD 196 + + + + G + +D+ +L AA+ + +VVC + Sbjct: 117 RGRLYPRMANVLSKQLGLSRALPLDSQMEAASFLLNLRLAASMIRQG--KAEKVLVVCSE 174 Query: 197 -IAVYPSGNARPT---GGAGAVAMLIGPKAP---LALERGLRGTHMENVYDFYKPNLASE 249 I+ +R + AVA+L L V + Sbjct: 175 YISNLLDFTSRTSTLFADGCAVALLTRGDDDSCDLLASAEHSDATFYEVATGRWRLPENP 234 Query: 250 YPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQ 309 +L + ++ + + ++A DD+ Y +FH P +V+ Sbjct: 235 TGEAKPRLYFSLFSDGQNKMASFVPTNVPIAMRRALEKAGLGSDDIDYFVFHQPAPFLVK 294 >3OIT-A nrPDB Length = 387 Score = 34.1 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 14/110 (12%) Query: 124 VGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWMESS 183 + L V T + V L+ L + + N C+ G A+L A + E+S Sbjct: 118 ITHLVVTTNSGA-HVPGVDFRLVPLLGLRPSVRRTMLHL-NGCFAGCAALRLAKDLAENS 175 Query: 184 SWDGRYAMVVCGDIA-VYPSGNARPT---------GGAGAVAMLIGPKAP 223 G +VV ++ +Y +G G GA A+++G A Sbjct: 176 R--GARVLVVAAELTLMYFTGPDEGCFRTLLVQGLFGDGAAAVIVGADAD 223 >2TLD-E nrPDB Length = 220 Score = 31.8 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 30/183 (16%), Positives = 54/183 (29%), Gaps = 7/183 (3%) Query: 242 YKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIFH 301 Y+ +L S Y G L ++ + CY S + + + I H Sbjct: 14 YQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVH 73 Query: 302 TPFCK-------MVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDK 354 + M+ K + N +++ S + G + + Sbjct: 74 PSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPD 133 Query: 355 ALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGS 414 L + + S Y NM+ + L G + +G G S+GS Sbjct: 134 VLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGGDSCQGDSGGPVVCSGKLQGIVSWGS 193 Query: 415 GLA 417 G A Sbjct: 194 GCA 196 >3V7I-A nrPDB Length = 413 Score = 28.7 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 51/328 (15%), Positives = 91/328 (27%), Gaps = 48/328 (14%) Query: 96 CSVQEDINSLCLTVVQRLMERIQLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNT 155 E + + + ++ L V L + + + L G+T Sbjct: 131 APAWEAVQAYGERAARGALQIAGLDVADVDCLIT-SNSTTPALPGLDVALANRLPLRGDT 189 Query: 156 DIEGIDTTNACYGGTASLFNAANWMESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVA 215 + T AC GT SL AA ++ R +VV + A T + V Sbjct: 190 MLLPA-TQWACVAGTRSLALAA--DLVAADPDRVVLVVISEALSTTYQPADDTLESLIVR 246 Query: 216 MLIGPKAPLALERGLRGTHMENVYDFYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRK 275 +L A A+ G +P S + LD + Sbjct: 247 LLFADTAVAAVVTG-------------RPRPES--------------VLRLDAAWHH--- 276 Query: 276 KIQNQWKQAGSDRPFTLDDLQYMIFHTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGL 335 R T D + + + VQ+++ + + D + L Sbjct: 277 ---TLPGTRDLHRLETRADGTHFVMDRRGPRAVQETVTAMWEWLRVRYEDDPSSWHPDVL 333 Query: 336 EAFGGLKLEDTYTNKDLDKALLKASQDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLS 395 A G Y + + + GN ++++ L Sbjct: 334 LAHPGGTRVLEYMEQTMPDEWPSGLLSYSRDSYTS--------GNRGGAAVFDILRRA-- 383 Query: 396 HHSAQELAGSRIGAFSYGSGLAASFFSF 423 H A + GSR ++ GL A+ Sbjct: 384 -HDAGQKTGSRAVLYAAAPGLTATALEG 410 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.114 0.273 Lambda K H 0.267 0.0348 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,416,393 Number of Sequences: 36641 Number of extensions: 552755 Number of successful extensions: 1684 Number of sequences better than 10.0: 35 Number of HSP's better than 10.0 without gapping: 29 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1549 Number of HSP's gapped (non-prelim): 69 length of query: 508 length of database: 10,336,785 effective HSP length: 101 effective length of query: 407 effective length of database: 6,636,044 effective search space: 2700869908 effective search space used: 2700869908 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.3 bits)