BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P54687 (386 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2COJ-A nrPDB 799 0.0 5BWR-A nrPDB 461 e-130 5U3F-A nrPDB 240 6e-64 3DTG-A nrPDB 225 3e-59 3UYY-A nrPDB 163 1e-40 4DQN-A nrPDB 161 4e-40 1IYD-A nrPDB 89 2e-18 4WHX-A nrPDB 73 2e-13 2EJ2-A nrPDB 72 4e-13 5CE8-A nrPDB 66 2e-11 6H65-A nrPDB 59 3e-09 6NST-A nrPDB 57 2e-08 3CSW-A nrPDB 40 0.002 6GKR-A nrPDB 38 0.009 3SNO-A nrPDB 31 0.93 2O59-A nrPDB 30 2.2 4N0Q-A nrPDB 28 6.6 >2COJ-A nrPDB Length = 386 Score = 799 bits (2064), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/386 (99%), Positives = 385/386 (99%) Query: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV Sbjct: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60 Query: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM Sbjct: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120 Query: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK Sbjct: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180 Query: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN Sbjct: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240 Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ Sbjct: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK Sbjct: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 Query: 361 LASRILSKLTDIQYGREESDWTIVLS 386 LASRILSKLTDIQYGREE DWTIVLS Sbjct: 361 LASRILSKLTDIQYGREERDWTIVLS 386 >5BWR-A nrPDB Length = 369 Score = 461 bits (1187), Expect = e-130, Method: Compositional matrix adjust. Identities = 216/366 (59%), Positives = 273/366 (74%), Gaps = 2/366 (0%) Query: 17 GSKEVVGTFKAKDLIVTPATILKEKPDPNN-LVFGTVFTDHMLTVEWSSEFGWEKPHIKP 75 GS +FKA DL + +KP P LVFG FTDHML VEW+ + GW +P I+P Sbjct: 1 GSHMASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQP 59 Query: 76 LQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKE 135 QNL+LHP SS+LHY+++LFEG+KAF+G D ++RLF+P LNMDRM RSA+R LP FDK Sbjct: 60 FQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKL 119 Query: 136 ELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFS 195 ELLECI++L+++D++WVP + SLY+RP IG EPSLGV +PT+ALLFV+L PVG YF Sbjct: 120 ELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFP 179 Query: 196 SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQI 255 G+ PVSL A+P ++RAW GG G+ K+GGNYG ++ Q EA+ GC+QVLWLYG DHQ+ Sbjct: 180 GGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQL 239 Query: 256 TEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDD 315 TEVGTMN+F+YW +EDG EL TPPL+G+ILPGV R+ +LD+A WGEF+V ER +TM Sbjct: 240 TEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQ 299 Query: 316 LTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375 L ALE RVRE+FGSGTAC VCPV ILYK +HIPTMENGP+L R +L +IQYG Sbjct: 300 LLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYG 359 Query: 376 REESDW 381 +W Sbjct: 360 IRAHEW 365 >5U3F-A nrPDB Length = 368 Score = 240 bits (613), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 132/346 (38%), Positives = 188/346 (54%), Gaps = 6/346 (1%) Query: 32 VTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYA 91 V PAT + + FG TDHM++++++ GW + P + L P + LHYA Sbjct: 14 VNPATDAQRESMLREPGFGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHYA 73 Query: 92 VELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEW 151 E+FEGLKA+R D I F+ + N R+ SA R +P +E ++QL+ +D+ W Sbjct: 74 QEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAW 133 Query: 152 VPYSTSA-SLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKY 210 VP + +LY+RP TEP LGV+ T+ ++ SP G YF G PVS+W + +Y Sbjct: 134 VPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG-IAPVSVWVSTEY 192 Query: 211 VRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWIN 269 VRA GGTG K GGNY +SL AQ EA +NGC QV+WL E I E+G MN+F + + Sbjct: 193 VRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF-FVLG 251 Query: 270 EDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMF 329 G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F Sbjct: 252 SGGSARLVTPELSGSLLPGITRDSLLQLAIDAG-FAVEERRIDIDEWQKKAAAGEITEVF 310 Query: 330 GSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375 GTA V+ PV+ + + I + G ++ + LT IQ G Sbjct: 311 ACGTAAVITPVARVRHGASEFRIADGQPG-EVTMALRDTLTGIQRG 355 >3DTG-A nrPDB Length = 372 Score = 225 bits (573), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 133/345 (38%), Positives = 188/345 (54%), Gaps = 6/345 (1%) Query: 33 TPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAV 92 PAT + N FG +TDHM++++++ + GW + P + L P + LHY Sbjct: 19 NPATDAVRESILANPGFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQ 78 Query: 93 ELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV 152 E+FEGLKA+R D I F+P N R+ SA R +P +E +E ++QL+ +D++WV Sbjct: 79 EIFEGLKAYRWADGSIVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWV 138 Query: 153 -PYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYV 211 P SLY+RP I TEP LGV+ + ++ SP G YF G PVS+W + +YV Sbjct: 139 PPAGGEESLYLRPFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGG-IKPVSVWLSHEYV 197 Query: 212 RAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWINE 270 RA GGTG K GGNY +SL AQ +A + GC QV+WL E + E+G MNLF + Sbjct: 198 RASPGGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVF-GS 256 Query: 271 DGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFG 330 G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F Sbjct: 257 GGSARLVTPELSGSLLPGITRDSLLQLATDAG-FAVEERKIDVDEWQKKAGAGEITEVFA 315 Query: 331 SGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375 GTA V+ PVS + + I + G ++ + LT IQ G Sbjct: 316 CGTAAVITPVSHVKHHDGEFTIADGQPG-EITMALRDTLTGIQRG 359 >3UYY-A nrPDB Length = 358 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 112/340 (32%), Positives = 168/340 (49%), Gaps = 17/340 (5%) Query: 43 DPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFR 102 D + L F + TD W + W+ + + L GS+ALHY + FEGLKA+R Sbjct: 25 DWSTLGFSYIRTDLRYLAHWK-DGEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYR 83 Query: 103 GVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSASLY 161 D I LF+P+ N RM S R +P E+ ++ Q+V+ ++ ++ PY T SLY Sbjct: 84 CADGSINLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLY 143 Query: 162 IRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDC 221 +RP IG ++GV+ + + V PVGPYF G P + + Y RA GTG Sbjct: 144 LRPFVIGVGDNIGVRTAPEFIFSVFCVPVGPYFKGG-LTPTNFITS-DYDRAAPHGTGAA 201 Query: 222 KMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELATPP 280 K+GGNY +SL EA V++L H I E G N F I +DG++ + P Sbjct: 202 KVGGNYAASLLPGYEAKKRDFADVIYLDPATHTTIEEAGAANFFA--ITQDGQKFVT--P 257 Query: 281 LDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPV 340 ILP +T+ +L LA +V E + +D+L + E GTA V+ P+ Sbjct: 258 QSPSILPSITKYSLLWLAEHRLGLEVEEGDIRIDEL------GKFSEAGACGTAAVITPI 311 Query: 341 SDILYKGETIHIPTMENGP-KLASRILSKLTDIQYGREES 379 I + G+ H+ E+ P + R+ +L IQYG +E+ Sbjct: 312 GGIQH-GDDFHVFYSESEPGPVTRRLYDELVGIQYGDKEA 350 >4DQN-A nrPDB Length = 345 Score = 161 bits (408), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 109/330 (33%), Positives = 166/330 (50%), Gaps = 21/330 (6%) Query: 53 FTDHMLTVEWSSEFG---WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIR 109 F H L + S + W+ + L + S ALHY E FEGLKA+R D ++ Sbjct: 16 FEYHKLPFRYISYYKDGKWDDGKLTEDATLHISESSPALHYGQEAFEGLKAYRTKDGSVQ 75 Query: 110 LFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSASLYIRPTFIG 168 LF+PN+N +R+ R+A R +P ++ ++ +Q+V+ ++E+V PY T A+LY+RP IG Sbjct: 76 LFRPNMNAERLQRTADRLLMPQVPTDKFIDAAKQVVRANEEYVPPYGTGATLYLRPLLIG 135 Query: 169 TEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYG 228 +GV + + + PVG YF G P + Y RA GTG K+GGNY Sbjct: 136 VGDVIGVHPADEYIFTIFAMPVGNYFKGG-LAPTNFLIQDDYDRAAPHGTGAAKVGGNYA 194 Query: 229 SSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELATPPLDGIILP 287 +SL A + V++L H +I EVG+ N F I +D E PL ILP Sbjct: 195 ASLLPGKVAHERQFSDVIYLDPATHTKIEEVGSANFF--GITKDNE---FITPLSPSILP 249 Query: 288 GVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKG 347 VT+ +L LA K E + +D+L ++ E GTA V+ P+ + + G Sbjct: 250 SVTKYSLLYLAEHRFGMKAIEGDVCVDEL------DKFVEAGACGTAAVISPIGGVQH-G 302 Query: 348 ETIHI--PTMENGPKLASRILSKLTDIQYG 375 + H+ E GP + ++ +LT IQ+G Sbjct: 303 DDFHVFYSETEVGP-VTHKLYDELTGIQFG 331 >1IYD-A nrPDB Length = 309 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 91/328 (27%), Positives = 142/328 (43%), Gaps = 42/328 (12%) Query: 64 SEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123 +++ W + ++ +H S ALHY +FEG++ + + +F+ +M R++ S Sbjct: 6 ADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV-VFRHREHMQRLHDS 64 Query: 124 AVRATLPVFDK-EELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKAL 182 A PV +EL+E + +++ + S YIRP + +GV P Sbjct: 65 AKIYRFPVSQSIDELMEACRDVIRKNN-------LTSAYIRPLIFVGDVGMGVNPPAGYS 117 Query: 183 LFVLLS--PVGPYFSS-----GTFNPVSLW--ANPKYVRAWKGGTGDCKMGGNYGSSLFA 233 V+++ P G Y + G VS W A P + K GGNY SSL Sbjct: 118 TDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPT------AAKAGGNYLSSLLV 171 Query: 234 QCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRC 293 EA +G Q+ + L + I+E NLF E + L TPP LPG+TR Sbjct: 172 GSEARRHGYQEGIAL-DVNGYISEGAGENLF-----EVKDGVLFTPPFTSSALPGITRDA 225 Query: 294 ILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIP 353 I+ LA + G +V E+ L+ + L A E+F SGTA + PV + + I + Sbjct: 226 IIKLAKELG-IEVREQVLSRESLYLA------DEVFMSGTAAEITPVRSV----DGIQVG 274 Query: 354 TMENGPKLASRILSKLTDIQYGREESDW 381 GP + RI + G E W Sbjct: 275 EGRCGP-VTKRIQQAFFGLFTGETEDKW 301 >4WHX-A nrPDB Length = 311 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 90/331 (27%), Positives = 145/331 (43%), Gaps = 55/331 (16%) Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127 W + ++ +H + LHY + +FEG++A++ D +F+ + R+ SA Sbjct: 15 WMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNSAKIF 74 Query: 128 TLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRP-TFIGTEPSLGVKKPTKALLFVL 186 + V +E LE Q+ V V + S Y+RP +IG+E LGV + + Sbjct: 75 QMDVPFDQETLEAAQRDV------VRENKLESCYLRPIIWIGSEK-LGVSAKGNTIHVAI 127 Query: 187 LS-PVGPYF-------------SSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLF 232 + P G Y SS T + V N VRA K G Y +S+ Sbjct: 128 AAWPWGAYLGEEGLAKGIRVKTSSFTRHHV----NVSMVRA--------KASGWYVNSIL 175 Query: 233 AQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRR 292 A EA +G + L L D ++E N FL +N +L TP L L G+TR Sbjct: 176 ANQEATADGYDEAL-LLDVDGYVSEGSGENFFL--VNRG---KLYTPDL-ASCLDGITRD 228 Query: 293 CILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHI 352 ++ LA + G +V E+ +T D++ TA E F +GTA V P+ ++ + I Sbjct: 229 TVITLAKEAG-IEVIEKRITRDEVYTA------DEAFFTGTAAEVTPIREL----DNRTI 277 Query: 353 PTMENGPKLASRILSKLTDIQYGR--EESDW 381 GP + ++ S D+ G+ + +DW Sbjct: 278 GGGARGP-ITEKLQSAFFDVVNGKSAKHADW 307 >2EJ2-A nrPDB Length = 308 Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 83/272 (30%), Positives = 118/272 (43%), Gaps = 38/272 (13%) Query: 85 SSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSA--VRATLPVFDKEELLECIQ 142 S ALHY +FEG++A+ +F+ ++ R Y SA +R +P F EEL E I+ Sbjct: 26 SHALHYGTSVFEGIRAYETAKGPA-IFRLKEHVKRFYNSAKVLRMEIP-FAPEELEEAIK 83 Query: 143 QLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKK--PTKALLFVLLSPVGPYFS----- 195 ++V+ + S YIRP +LGV A + V G Y Sbjct: 84 EVVRRN-------GYRSCYIRPLAWMGAKALGVNPLPNNPAEVMVAAWEWGAYLGEEAVR 136 Query: 196 SGTFNPVSLWAN-PKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQ 254 G S WA P V G K+GGNY +S A+ EAV G + L L E+ Sbjct: 137 KGARLITSSWARFPANVM-----PGKAKVGGNYVNSALAKMEAVAAGADEAL-LLDEEGY 190 Query: 255 ITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMD 314 + E NLF DG + + L G+TR ++ +A G ++V T D Sbjct: 191 VAEGSGENLFFV---RDG---VIYALEHSVNLEGITRDSVIRIAKDLG-YEVQVVRATRD 243 Query: 315 DLTTALEGNRVREMFGSGTACVVCPVSDILYK 346 L A E+F +GTA V PVS I ++ Sbjct: 244 QLYMA------DEVFMTGTAAEVTPVSMIDWR 269 >5CE8-A nrPDB Length = 307 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 35/297 (11%) Query: 85 SSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPV-FDKEELLECIQQ 143 S +L+Y +FEG++A+ +N + +F+ +M+R+ RSA L V + EEL + + + Sbjct: 33 SPSLNYGFGVFEGIRAYWNGEN-LYVFRLRDHMERLLRSAKIIGLDVPYTAEELSKAVVE 91 Query: 144 LVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVK-KPTKALLFVLLSPVGPYFS-SGTFNP 201 V+ + LYIRP ++P + + + +A + + P G Y G Sbjct: 92 TVRAN------GFKEDLYIRPVAYISKPQISLDVRGLQASVAIAAIPFGKYLKVEGVRAA 145 Query: 202 VSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTM 261 V W K G Y +S+ A EA G + + L E ++ E Sbjct: 146 VVSWRRVHTSMM----PVMAKATGIYLNSIMAAVEARARGYDEAIMLNAEG-KVVEGSGE 200 Query: 262 NLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALE 321 N+F+ L TPPL+ IL G+TR ++ +A G + E+ +T ++L A Sbjct: 201 NIFIVR-----RGVLMTPPLEDGILEGITRETVISIAGDLG-IPLLEKSITREELYAA-- 252 Query: 322 GNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYGREE 378 E F GTA + P+ +I + ++ GP + +I I G+EE Sbjct: 253 ----DEAFFVGTAAEITPIIEIDGR-------VLQRGP-ITQKIAETYRRIVLGKEE 297 >6H65-A nrPDB Length = 317 Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 72/330 (21%), Positives = 140/330 (42%), Gaps = 63/330 (19%) Query: 65 EFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDN-KIRLFQPNLNMDRMYRS 123 +GW P SLH + A + LFEG++A+ + ++ +F+ + ++ R+ +S Sbjct: 14 RYGWMNGQCIPWDQCSLHVSTQAAFFGASLFEGVRAYWNAEREQLYVFRLDEHLRRLEQS 73 Query: 124 A----VRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTF-IGTEPSLGVKKP 178 A ++ ++P+ D + + + +L++ ++ + + LY+ F I +P Sbjct: 74 AKMLRMKLSMPIAD---IRQGVLELLRANE----FRSDVHLYVASYFGINHDPD------ 120 Query: 179 TKALLFVLLSPVGPYFSSGTFN--------PVSLWANPKYVRAWKGGTGDC-----KMGG 225 P+ P +G + P+ + +W+ + D K+G Sbjct: 121 ----------PLFPTDDTGVYVTGTAVSRLPLVHTGISACMSSWRRISDDSVPPRIKIGA 170 Query: 226 NYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGII 285 NY +S AQ EA NG + L +++E L + DG + +PP+ I Sbjct: 171 NYQNSRLAQTEARVNGYHTSV-LLNSRGKVSETPGACLLMV---RDGR--VISPPVTADI 224 Query: 286 LPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY 345 L VTR+ ++ L+ + V ER + +L A E+F GT + PV+ I Sbjct: 225 LESVTRKTLMSLSEAELDSPVIERDMDRTELYIA------EEVFLCGTIAEILPVTTI-- 276 Query: 346 KGETIHIPTMENGPKLASRILSKLTDIQYG 375 + I + E GP + +L ++ +G Sbjct: 277 --DRIQVGDGEVGP-----VTRRLQELYFG 299 >6NST-A nrPDB Length = 307 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 66/258 (25%), Positives = 114/258 (44%), Gaps = 27/258 (10%) Query: 90 YAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPV-FDKEELLECIQQLVKLD 148 Y + +FEG++A+ +F+ + DR++ SA + + + ++E+ E + V+ + Sbjct: 33 YGMGVFEGVRAY-DTPQGTAIFRLQAHTDRLFDSAHIMNMQIPYSRDEINEATRAAVREN 91 Query: 149 QEWVPYSTSASLYIRP-TFIGTEPSLGVKKP-TKALLFVLLSPVGPYFSSGTFNPVSLWA 206 S YIRP F G+E +G++ K + + G Y Sbjct: 92 N-------LESAYIRPMVFYGSE-GMGLRASGLKVHVIIAAWSWGAYMGEEALQQGIKVR 143 Query: 207 NPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFL 265 + R K G Y +S+ A EA+ G + + L E + + E N+F Sbjct: 144 TSSFTRHHVNISMTRAKSNGAYINSMLALQEAISGGADEAMMLDPEGY-VAEGSGENIF- 201 Query: 266 YWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRV 325 I +DG + TP + L G+TR IL LA + G FK+ E+ +T D++ A Sbjct: 202 --IIKDG--VIYTPEVTA-CLNGITRNTILTLAAEHG-FKLVEKRITRDEVYIA------ 249 Query: 326 REMFGSGTACVVCPVSDI 343 E F +GTA V P+ ++ Sbjct: 250 DEAFFTGTAAEVTPIREV 267 >3CSW-A nrPDB Length = 285 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 15/110 (13%) Query: 231 LFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVT 290 + A+ E VD C V+ L G + Q+ E N+FL E +L TP LD IL G+T Sbjct: 153 VLARREIVD--CYDVI-LLGLNGQVCEGSFSNVFLV-----KEGKLITPSLDSGILDGIT 204 Query: 291 RRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPV 340 R ++ LA E V ER + + +L A EMF + T+ V PV Sbjct: 205 RENVIKLAKSL-EIPVEERVVWVWELFEA------DEMFLTHTSAGVVPV 247 >6GKR-A nrPDB Length = 316 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 12/122 (9%) Query: 222 KMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPL 281 K NY +S A EA NG L+L E G+ F+ + +L TP + Sbjct: 160 KALANYRNSQLASSEAAMNGYDTALFLNPEGKVAEGTGSCVFFV------RKGKLITPDI 213 Query: 282 DGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVS 341 IL +TR ++ LA + +V ER +D T L E F GT + P++ Sbjct: 214 TSGILESITRDTVIHLAREVLGLEVEER--VVDRTETYLAD----EAFLCGTHAEITPIA 267 Query: 342 DI 343 I Sbjct: 268 SI 269 >3SNO-A nrPDB Length = 315 Score = 30.8 bits (68), Expect = 0.93, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 8/90 (8%) Query: 227 YGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIIL 286 Y +++ A A NG V++ G+ ++ E T + + +++ TP G IL Sbjct: 190 YAANMAALRYAKSNGFDDVIFTDGD--RVLEGATSTVVSF-----KGDKIRTPSPGGDIL 242 Query: 287 PGVTRRCILDLAHQWGEFKVSERYLTMDDL 316 PG T+ + A + G ++ E+ L++DDL Sbjct: 243 PGTTQAALFAHATEKG-WRCKEKDLSIDDL 271 >2O59-A nrPDB Length = 659 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 3/100 (3%) Query: 288 GVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY-- 345 V R+C+++L G+F R+L T L G++ R+ GT V D L Sbjct: 418 AVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL-GSKERDEENDGTPLPVVAKGDELLCE 476 Query: 346 KGETIHIPTMENGPKLASRILSKLTDIQYGREESDWTIVL 385 KGE + T + +LS +T I ++ D +L Sbjct: 477 KGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKIL 516 >4N0Q-A nrPDB Length = 354 Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 24/48 (50%) Query: 322 GNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKL 369 G+ ++ + G T V PVSD+L + + + GP L +R L + Sbjct: 75 GDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENV 122 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2COJ-A nrPDB 594 e-170 5BWR-A nrPDB 498 e-141 5U3F-A nrPDB 429 e-121 3DTG-A nrPDB 418 e-117 3UYY-A nrPDB 383 e-107 4DQN-A nrPDB 367 e-102 1IYD-A nrPDB 317 7e-87 4WHX-A nrPDB 312 2e-85 5CE8-A nrPDB 272 2e-73 6NST-A nrPDB 267 8e-72 6H65-A nrPDB 266 1e-71 2EJ2-A nrPDB 264 6e-71 3CSW-A nrPDB 123 1e-28 Sequences not found previously or not previously below threshold: 6GKR-A nrPDB 200 8e-52 5MQZ-A nrPDB 180 7e-46 5E25-A nrPDB 174 5e-44 4JXU-A nrPDB 107 9e-24 1G2W-A nrPDB 102 3e-22 4PBC-A nrPDB 89 2e-18 4TM5-A nrPDB 85 6e-17 4UUG-A nrPDB 73 2e-13 2Y4R-A nrPDB 72 5e-13 3SNO-A nrPDB 55 4e-08 4K6N-A nrPDB 39 0.003 2V2T-A nrPDB 31 1.4 5T49-A nrPDB 30 1.6 5FXF-A nrPDB 30 1.8 1QNO-A nrPDB 30 2.3 6ED1-A nrPDB 30 2.3 6D8K-A nrPDB 29 2.9 >2COJ-A nrPDB Length = 386 Score = 594 bits (1530), Expect = e-170, Method: Composition-based stats. Identities = 385/386 (99%), Positives = 385/386 (99%) Query: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV Sbjct: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60 Query: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM Sbjct: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120 Query: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK Sbjct: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180 Query: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN Sbjct: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240 Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ Sbjct: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK Sbjct: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 Query: 361 LASRILSKLTDIQYGREESDWTIVLS 386 LASRILSKLTDIQYGREE DWTIVLS Sbjct: 361 LASRILSKLTDIQYGREERDWTIVLS 386 >5BWR-A nrPDB Length = 369 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 215/366 (58%), Positives = 272/366 (74%), Gaps = 2/366 (0%) Query: 17 GSKEVVGTFKAKDLIVTPATILKEKPDPNNL-VFGTVFTDHMLTVEWSSEFGWEKPHIKP 75 GS +FKA DL + +KP P VFG FTDHML VEW+ + GW +P I+P Sbjct: 1 GSHMASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQP 59 Query: 76 LQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKE 135 QNL+LHP SS+LHY+++LFEG+KAF+G D ++RLF+P LNMDRM RSA+R LP FDK Sbjct: 60 FQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKL 119 Query: 136 ELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFS 195 ELLECI++L+++D++WVP + SLY+RP IG EPSLGV +PT+ALLFV+L PVG YF Sbjct: 120 ELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFP 179 Query: 196 SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQI 255 G+ PVSL A+P ++RAW GG G+ K+GGNYG ++ Q EA+ GC+QVLWLYG DHQ+ Sbjct: 180 GGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQL 239 Query: 256 TEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDD 315 TEVGTMN+F+YW +EDG EL TPPL+G+ILPGV R+ +LD+A WGEF+V ER +TM Sbjct: 240 TEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQ 299 Query: 316 LTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375 L ALE RVRE+FGSGTAC VCPV ILYK +HIPTMENGP+L R +L +IQYG Sbjct: 300 LLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYG 359 Query: 376 REESDW 381 +W Sbjct: 360 IRAHEW 365 >5U3F-A nrPDB Length = 368 Score = 429 bits (1103), Expect = e-121, Method: Composition-based stats. Identities = 132/346 (38%), Positives = 187/346 (54%), Gaps = 6/346 (1%) Query: 32 VTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYA 91 V PAT + + FG TDHM++++++ GW + P + L P + LHYA Sbjct: 14 VNPATDAQRESMLREPGFGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHYA 73 Query: 92 VELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEW 151 E+FEGLKA+R D I F+ + N R+ SA R +P +E ++QL+ +D+ W Sbjct: 74 QEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAW 133 Query: 152 VPYSTS-ASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKY 210 VP + +LY+RP TEP LGV+ T+ ++ SP G YF G PVS+W + +Y Sbjct: 134 VPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG-IAPVSVWVSTEY 192 Query: 211 VRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWIN 269 VRA GGTG K GGNY +SL AQ EA +NGC QV+WL E I E+G MN+F + Sbjct: 193 VRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIFFV-LG 251 Query: 270 EDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMF 329 G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F Sbjct: 252 SGGSARLVTPELSGSLLPGITRDSLLQLAIDAG-FAVEERRIDIDEWQKKAAAGEITEVF 310 Query: 330 GSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375 GTA V+ PV+ + + I + G ++ + LT IQ G Sbjct: 311 ACGTAAVITPVARVRHGASEFRIADGQPG-EVTMALRDTLTGIQRG 355 >3DTG-A nrPDB Length = 372 Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats. Identities = 133/345 (38%), Positives = 188/345 (54%), Gaps = 6/345 (1%) Query: 33 TPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAV 92 PAT + N FG +TDHM++++++ + GW + P + L P + LHY Sbjct: 19 NPATDAVRESILANPGFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQ 78 Query: 93 ELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV 152 E+FEGLKA+R D I F+P N R+ SA R +P +E +E ++QL+ +D++WV Sbjct: 79 EIFEGLKAYRWADGSIVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWV 138 Query: 153 -PYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYV 211 P SLY+RP I TEP LGV+ + ++ SP G YF G PVS+W + +YV Sbjct: 139 PPAGGEESLYLRPFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGG-IKPVSVWLSHEYV 197 Query: 212 RAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWINE 270 RA GGTG K GGNY +SL AQ +A + GC QV+WL E + E+G MNLF + Sbjct: 198 RASPGGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVF-GS 256 Query: 271 DGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFG 330 G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F Sbjct: 257 GGSARLVTPELSGSLLPGITRDSLLQLATDAG-FAVEERKIDVDEWQKKAGAGEITEVFA 315 Query: 331 SGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375 GTA V+ PVS + + I + G ++ + LT IQ G Sbjct: 316 CGTAAVITPVSHVKHHDGEFTIADGQPG-EITMALRDTLTGIQRG 359 >3UYY-A nrPDB Length = 358 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 112/340 (32%), Positives = 167/340 (49%), Gaps = 17/340 (5%) Query: 43 DPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFR 102 D + L F + TD W + W+ + + L GS+ALHY + FEGLKA+R Sbjct: 25 DWSTLGFSYIRTDLRYLAHWK-DGEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYR 83 Query: 103 GVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSASLY 161 D I LF+P+ N RM S R +P E+ ++ Q+V+ ++ ++ PY T SLY Sbjct: 84 CADGSINLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLY 143 Query: 162 IRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDC 221 +RP IG ++GV+ + + V PVGPYF G P + Y RA GTG Sbjct: 144 LRPFVIGVGDNIGVRTAPEFIFSVFCVPVGPYFKGG-LTPTNFI-TSDYDRAAPHGTGAA 201 Query: 222 KMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELATPP 280 K+GGNY +SL EA V++L H I E G N F I +DG++ + P Sbjct: 202 KVGGNYAASLLPGYEAKKRDFADVIYLDPATHTTIEEAGAANFFA--ITQDGQKFV--TP 257 Query: 281 LDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPV 340 ILP +T+ +L LA +V E + +D+L + E GTA V+ P+ Sbjct: 258 QSPSILPSITKYSLLWLAEHRLGLEVEEGDIRIDEL------GKFSEAGACGTAAVITPI 311 Query: 341 SDILYKGETIHIPTMENGP-KLASRILSKLTDIQYGREES 379 I + G+ H+ E+ P + R+ +L IQYG +E+ Sbjct: 312 GGIQH-GDDFHVFYSESEPGPVTRRLYDELVGIQYGDKEA 350 >4DQN-A nrPDB Length = 345 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 112/344 (32%), Positives = 171/344 (49%), Gaps = 25/344 (7%) Query: 43 DPNNLVFGTVFTDHMLTVEWSSEFG---WEKPHIKPLQNLSLHPGSSALHYAVELFEGLK 99 D NL F H L + S + W+ + L + S ALHY E FEGLK Sbjct: 10 DWKNLGF----EYHKLPFRYISYYKDGKWDDGKLTEDATLHISESSPALHYGQEAFEGLK 65 Query: 100 AFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSA 158 A+R D ++LF+PN+N +R+ R+A R +P ++ ++ +Q+V+ ++E+V PY T A Sbjct: 66 AYRTKDGSVQLFRPNMNAERLQRTADRLLMPQVPTDKFIDAAKQVVRANEEYVPPYGTGA 125 Query: 159 SLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGT 218 +LY+RP IG +GV + + + PVG YF G P + Y RA GT Sbjct: 126 TLYLRPLLIGVGDVIGVHPADEYIFTIFAMPVGNYFKGG-LAPTNFLIQDDYDRAAPHGT 184 Query: 219 GDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELA 277 G K+GGNY +SL A + V++L H +I EVG+ N F I +D E Sbjct: 185 GAAKVGGNYAASLLPGKVAHERQFSDVIYLDPATHTKIEEVGSANFF--GITKDNE---F 239 Query: 278 TPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVV 337 PL ILP VT+ +L LA K E + +D+L ++ E GTA V+ Sbjct: 240 ITPLSPSILPSVTKYSLLYLAEHRFGMKAIEGDVCVDEL------DKFVEAGACGTAAVI 293 Query: 338 CPVSDILYKGETIHI--PTMENGPKLASRILSKLTDIQYGREES 379 P+ + + G+ H+ E GP + ++ +LT IQ+G ++ Sbjct: 294 SPIGGVQH-GDDFHVFYSETEVGP-VTHKLYDELTGIQFGDVKA 335 >1IYD-A nrPDB Length = 309 Score = 317 bits (811), Expect = 7e-87, Method: Composition-based stats. Identities = 86/323 (26%), Positives = 136/323 (42%), Gaps = 30/323 (9%) Query: 63 SSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYR 122 +++ W + ++ +H S ALHY +FEG++ + + +F+ +M R++ Sbjct: 5 KADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV-VFRHREHMQRLHD 63 Query: 123 SAVRATLPVFDK-EELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKA 181 SA PV +EL+E + +++ + S YIRP + +GV P Sbjct: 64 SAKIYRFPVSQSIDELMEACRDVIRKNN-------LTSAYIRPLIFVGDVGMGVNPPAGY 116 Query: 182 L--LFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAV 238 + + P G Y + + RA K GGNY SSL EA Sbjct: 117 STDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGSEAR 176 Query: 239 DNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLA 298 +G Q+ + L + I+E NLF E + L TPP LPG+TR I+ LA Sbjct: 177 RHGYQEGIALD-VNGYISEGAGENLF-----EVKDGVLFTPPFTSSALPGITRDAIIKLA 230 Query: 299 HQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENG 358 + G +V E+ L+ + L A E+F SGTA + PV + + I + G Sbjct: 231 KELG-IEVREQVLSRESLYLA------DEVFMSGTAAEITPVRSV----DGIQVGEGRCG 279 Query: 359 PKLASRILSKLTDIQYGREESDW 381 P + RI + G E W Sbjct: 280 P-VTKRIQQAFFGLFTGETEDKW 301 >4WHX-A nrPDB Length = 311 Score = 312 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 79/322 (24%), Positives = 130/322 (40%), Gaps = 29/322 (9%) Query: 64 SEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123 W + ++ +H + LHY + +FEG++A++ D +F+ + R+ S Sbjct: 11 DGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNS 70 Query: 124 AVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALL 183 A + V +E LE Q+ V V + S Y+RP LGV + Sbjct: 71 AKIFQMDVPFDQETLEAAQRDV------VRENKLESCYLRPIIWIGSEKLGVSAKGNTIH 124 Query: 184 F-VLLSPVGPYFSSGTFNPVSLWANPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAVDNG 241 + P G Y + R K G Y +S+ A EA +G Sbjct: 125 VAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADG 184 Query: 242 CQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQW 301 + L L D ++E N FL +L TP L L G+TR ++ LA + Sbjct: 185 YDEAL-LLDVDGYVSEGSGENFFLV-----NRGKLYTPDL-ASCLDGITRDTVITLAKEA 237 Query: 302 GEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKL 361 G +V E+ +T D++ TA E F +GTA V P+ ++ + I GP + Sbjct: 238 G-IEVIEKRITRDEVYTA------DEAFFTGTAAEVTPIREL----DNRTIGGGARGP-I 285 Query: 362 ASRILSKLTDIQYGR--EESDW 381 ++ S D+ G+ + +DW Sbjct: 286 TEKLQSAFFDVVNGKSAKHADW 307 >5CE8-A nrPDB Length = 307 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 77/314 (24%), Positives = 134/314 (42%), Gaps = 35/314 (11%) Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127 W + + + S +L+Y +FEG++A+ +N + +F+ +M+R+ RSA Sbjct: 16 WLDGRLVDEEEAKVTVLSPSLNYGFGVFEGIRAYWNGEN-LYVFRLRDHMERLLRSAKII 74 Query: 128 TLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVK-KPTKALLFV 185 L V + EEL + + + V+ + LYIRP ++P + + + +A + + Sbjct: 75 GLDVPYTAEELSKAVVETVRAN------GFKEDLYIRPVAYISKPQISLDVRGLQASVAI 128 Query: 186 LLSPVGPYFS-SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQ 244 P G Y G V W K G Y +S+ A EA G + Sbjct: 129 AAIPFGKYLKVEGVRAAVVSWRRVHTSMM----PVMAKATGIYLNSIMAAVEARARGYDE 184 Query: 245 VLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEF 304 + L E ++ E N+F+ L TPPL+ IL G+TR ++ +A G Sbjct: 185 AIMLNAE-GKVVEGSGENIFIVR-----RGVLMTPPLEDGILEGITRETVISIAGDLG-I 237 Query: 305 KVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASR 364 + E+ +T ++L A E F GTA + P+ +I + ++ GP + + Sbjct: 238 PLLEKSITREELYAA------DEAFFVGTAAEITPIIEIDGR-------VLQRGP-ITQK 283 Query: 365 ILSKLTDIQYGREE 378 I I G+EE Sbjct: 284 IAETYRRIVLGKEE 297 >6NST-A nrPDB Length = 307 Score = 267 bits (681), Expect = 8e-72, Method: Composition-based stats. Identities = 70/323 (21%), Positives = 130/323 (40%), Gaps = 32/323 (9%) Query: 64 SEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123 W + ++ + H + HY + +FEG++A+ +F+ + DR++ S Sbjct: 7 DGVIWYDGELVQWRDATTHVLTHTHHYGMGVFEGVRAYDT-PQGTAIFRLQAHTDRLFDS 65 Query: 124 AVRATLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPT-KA 181 A + + + ++E+ E + V+ + S YIRP +G++ K Sbjct: 66 AHIMNMQIPYSRDEINEATRAAVRENN-------LESAYIRPMVFYGSEGMGLRASGLKV 118 Query: 182 LLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAVDN 240 + + G Y + R K G Y +S+ A EA+ Sbjct: 119 HVIIAAWSWGAYMGEEALQQGIKVRTSSFTRHHVNISMTRAKSNGAYINSMLALQEAISG 178 Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 G + + L E + E N+F+ + + TP + L G+TR IL LA + Sbjct: 179 GADEAMMLDPE-GYVAEGSGENIFII-----KDGVIYTPEVTA-CLNGITRNTILTLAAE 231 Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 G FK+ E+ +T D++ A E F +GTA V P+ ++ + I GP Sbjct: 232 HG-FKLVEKRITRDEVYIA------DEAFFTGTAAEVTPIREV----DGRKIGAGRRGP- 279 Query: 361 LASRILSKLTDIQYGREE--SDW 381 + ++ D+ G+ E ++W Sbjct: 280 VTEKLQKAYFDLVSGKTEAHAEW 302 >6H65-A nrPDB Length = 317 Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats. Identities = 71/334 (21%), Positives = 140/334 (41%), Gaps = 59/334 (17%) Query: 65 EFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDN-KIRLFQPNLNMDRMYRS 123 +GW P SLH + A + LFEG++A+ + ++ +F+ + ++ R+ +S Sbjct: 14 RYGWMNGQCIPWDQCSLHVSTQAAFFGASLFEGVRAYWNAEREQLYVFRLDEHLRRLEQS 73 Query: 124 A----VRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTF-IGTEPSLGVKKP 178 A ++ ++P+ D + + + +L++ ++ + + LY+ F I +P Sbjct: 74 AKMLRMKLSMPIAD---IRQGVLELLRANE----FRSDVHLYVASYFGINHDPD------ 120 Query: 179 TKALLFVLLSPVGPYFSSGTFN--------PVSLWANPKYVRAWKGGTGDC-----KMGG 225 P+ P +G + P+ + +W+ + D K+G Sbjct: 121 ----------PLFPTDDTGVYVTGTAVSRLPLVHTGISACMSSWRRISDDSVPPRIKIGA 170 Query: 226 NYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGII 285 NY +S AQ EA NG + L +++E L + + + +PP+ I Sbjct: 171 NYQNSRLAQTEARVNGYHTSV-LLNSRGKVSETPGACLLMVR-----DGRVISPPVTADI 224 Query: 286 LPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY 345 L VTR+ ++ L+ + V ER + +L A E+F GT + PV+ I Sbjct: 225 LESVTRKTLMSLSEAELDSPVIERDMDRTELYIA------EEVFLCGTIAEILPVTTI-- 276 Query: 346 KGETIHIPTMENGPKLASRILSKLTDIQYGREES 379 + I + E GP + R+ + G+ E+ Sbjct: 277 --DRIQVGDGEVGP-VTRRLQELYFGVTSGQLEA 307 >2EJ2-A nrPDB Length = 308 Score = 264 bits (674), Expect = 6e-71, Method: Composition-based stats. Identities = 90/324 (27%), Positives = 130/324 (40%), Gaps = 41/324 (12%) Query: 63 SSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYR 122 + W P + S ALHY +FEG++A+ +F+ ++ R Y Sbjct: 4 KAGLIWMNGAFVPQEEAKTSVLSHALHYGTSVFEGIRAYETAKGP-AIFRLKEHVKRFYN 62 Query: 123 SAVRATLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVK--KPT 179 SA + + F EEL E I+++V+ + S YIRP +LGV Sbjct: 63 SAKVLRMEIPFAPEELEEAIKEVVRRN-------GYRSCYIRPLAWMGAKALGVNPLPNN 115 Query: 180 KALLFVLLSPVGPYFSS-----GTFNPVSLWAN-PKYVRAWKGGTGDCKMGGNYGSSLFA 233 A + V G Y G S WA P V G K+GGNY +S A Sbjct: 116 PAEVMVAAWEWGAYLGEEAVRKGARLITSSWARFPANVM-----PGKAKVGGNYVNSALA 170 Query: 234 QCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRC 293 + EAV G + L L E+ + E NLF DG + + L G+TR Sbjct: 171 KMEAVAAGADEAL-LLDEEGYVAEGSGENLFFV---RDG---VIYALEHSVNLEGITRDS 223 Query: 294 ILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIP 353 ++ +A G ++V T D L A E+F +GTA V PVS I ++ I Sbjct: 224 VIRIAKDLG-YEVQVVRATRDQLYMA------DEVFMTGTAAEVTPVSMIDWRP----IG 272 Query: 354 TMENGPKLASRILSKLTDIQYGRE 377 GP +A R+ + GR Sbjct: 273 KGTAGP-VALRLREVYLEAVTGRR 295 >6GKR-A nrPDB Length = 316 Score = 200 bits (508), Expect = 8e-52, Method: Composition-based stats. Identities = 62/326 (19%), Positives = 117/326 (35%), Gaps = 34/326 (10%) Query: 63 SSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRG-VDNKIRLFQPNLNMDRMY 121 + ++ W I P + ++H +FEG++ + + ++ +F+ + R+ Sbjct: 6 NPKYLWWNHRIIPWEEATVHLTDYWWASVTAVFEGIRGYWNNAEGEMYIFRLEDHARRLE 65 Query: 122 RSAVRATLP-VFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTE-PSLGVKKPT 179 +S +P F +E+ + LV+ + +YI P + V Sbjct: 66 QSMQLIRMPKEFTVDEICQATIDLVRANDYR------GDVYIMPLAYAVGNKAFSVVGDR 119 Query: 180 KALLFVLLSPVGPYFSSGTFNPV--SLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEA 237 +F+ P S W + K NY +S A EA Sbjct: 120 TTEMFIYSRPAVSRLEEDFSLHACYSSWTRIN----ERVLPPRIKALANYRNSQLASSEA 175 Query: 238 VDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDL 297 NG L+L E ++ E +F + +L TP + IL +TR ++ L Sbjct: 176 AMNGYDTALFLNPE-GKVAEGTGSCVFFVR-----KGKLITPDITSGILESITRDTVIHL 229 Query: 298 AHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMEN 357 A + +V ER + + A E F GT + P++ I + + Sbjct: 230 AREVLGLEVEERVVDRTETYLA------DEAFLCGTHAEITPIASI----DRHEMKHGAP 279 Query: 358 GPKLASRILSKLTDIQYGR--EESDW 381 GP + ++ ++ YGR +W Sbjct: 280 GP-ITRQLRDIYREVVYGRDFRYRNW 304 >5MQZ-A nrPDB Length = 290 Score = 180 bits (457), Expect = 7e-46, Method: Composition-based stats. Identities = 62/314 (19%), Positives = 121/314 (38%), Gaps = 43/314 (13%) Query: 66 FGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAV 125 + + P + Y +FEG++A+ G R+F+ ++DR+Y SA Sbjct: 3 YVYMDGEFVPENEAKVSIFDHGFLYGDGVFEGIRAYNG-----RVFRLKEHIDRLYDSAK 57 Query: 126 RATLPVF-DKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKP--TKAL 182 L + KEE +E I + ++ + YIRP LG+ Sbjct: 58 AIDLEIPITKEEFMEIILETLRKNN-------LRDAYIRPIVTRGIGDLGLDPRKCQNPS 110 Query: 183 LFVLLSPVGPYFS----SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAV 238 + V+ P G + G + NY +++ A+ EA Sbjct: 111 IIVITKPWGKLYGDLYEKGLTAITVAVRRNSFDALPPNIKSL-----NYLNNILAKIEAN 165 Query: 239 DNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLA 298 G + ++L + ++E N+F+ + TPP L G+TR ++++ Sbjct: 166 AKGGDEAIFLD-RNGYVSEGSGDNIFVV-----KNGAITTPP-TINNLRGITREAVIEII 218 Query: 299 HQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENG 358 ++ G E + + DL TA E+F +GTA + P+ I + I + G Sbjct: 219 NRLG-IPFKETNIGLYDLYTA------DEVFVTGTAAEIAPIVVI----DGRKIGDGKPG 267 Query: 359 PKLASRILSKLTDI 372 ++ +++ + + + Sbjct: 268 -EITRKLMEEFSKL 280 >5E25-A nrPDB Length = 291 Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats. Identities = 62/311 (19%), Positives = 116/311 (37%), Gaps = 43/311 (13%) Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127 + P + Y +FEG++A+ G +F+ ++DR+Y A Sbjct: 6 YMNGEFVPESQAKVSVFDHGFLYGDGVFEGIRAYNGK-----VFKLYEHIDRLYDCARVI 60 Query: 128 TLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKP--TKALLF 184 L + KEE E I + ++ + YIRP LG+ + Sbjct: 61 DLKIPLSKEEFAEAILETLRRNN-------LRDAYIRPIVTRGAGDLGLDPRKCPSPNVI 113 Query: 185 VLLSPVGPYFS----SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240 ++ P G + G NY +++ A+ EA Sbjct: 114 IITKPWGKLYGDLYEKGLKAITVAIRRNAIDSLPPNIKSL-----NYLNNILAKIEANAK 168 Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 G + ++L + I+E N+F+ + TPP L G+TR+ +++L ++ Sbjct: 169 GGDEAIFLD-HNGYISEGSGDNIFIV-----KNGTITTPP-TLNNLKGITRQVVIELINE 221 Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 E E + + DL +A E+F +GTA + PV+ I + + + G K Sbjct: 222 L-EIPFREANIGLFDLYSA------DEIFVTGTAAEIAPVTYI----DGRTVGNGKPG-K 269 Query: 361 LASRILSKLTD 371 + ++ K + Sbjct: 270 VTKMLMEKFRE 280 >3CSW-A nrPDB Length = 285 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 68/316 (21%), Positives = 112/316 (35%), Gaps = 51/316 (16%) Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127 W + + +SL ++E L+ + F + R+ RSA Sbjct: 16 WWRGKFRRADEISLDFSLFEKSLQGAVYETLRTYSRAP-----FAAYKHYTRLKRSADFF 70 Query: 128 TLP-VFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVL 186 LP +E + ++K + +Y+ P + + Sbjct: 71 NLPLSLSFDEFTK----VLKAGADEFKQEVRIKVYLFP--------------DSGEVLFV 112 Query: 187 LSPVG-PYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQV 245 SP+ P +G +S + K+ G + A+ E VD C V Sbjct: 113 FSPLNIPDLETGVEVKISNVRRIPDLSTPP----ALKITGR-TDIVLARREIVD--CYDV 165 Query: 246 LWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFK 305 + L G + Q+ E N+FL E +L TP LD IL G+TR ++ LA E Sbjct: 166 I-LLGLNGQVCEGSFSNVFLV-----KEGKLITPSLDSGILDGITRENVIKLAKSL-EIP 218 Query: 306 VSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRI 365 V ER + + +L A EMF + T+ V PV + E GP + + + Sbjct: 219 VEERVVWVWELFEA------DEMFLTHTSAGVVPVRRLNEHS----FFEEEPGP-VTATL 267 Query: 366 LSKLTDIQYGREESDW 381 + EE +W Sbjct: 268 MENFEPFVLNLEE-NW 282 >4JXU-A nrPDB Length = 295 Score = 107 bits (266), Expect = 9e-24, Method: Composition-based stats. Identities = 68/308 (22%), Positives = 111/308 (36%), Gaps = 39/308 (12%) Query: 65 EFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSA 124 + W + P S A+ +F+G + F G+ +L+ R+ RSA Sbjct: 18 DGEWLAG-----NPPLIGPTSHAMWLGSTVFDGARWFDGIAPD-----LDLHCQRVNRSA 67 Query: 125 VRATL-PVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALL 183 L P EE+ + VK + ++Y++P + G S V Sbjct: 68 EALGLKPTMSAEEIEGLAWEGVKK------FDGKTAIYVKPMYWGEHGSWSVVAVDPEST 121 Query: 184 FVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQ 243 L +G SL +P + D K G Y ++ EA G Sbjct: 122 RFALCLFEAPMGNG-HAGSSLTLSPFRRPTLECMPTDAKAGCLYPNNARILNEARSRGFD 180 Query: 244 QVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGE 303 L I E G+ N+F+ + + TP + L G+TR ++ L + G Sbjct: 181 NALVRDML-GNIAETGSSNIFMV-----KDGVVFTPAANRTFLAGITRSRVMGLLSEAG- 233 Query: 304 FKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLAS 363 F+V E LTM D A E+F SG V PV+ + + ++ GP + + Sbjct: 234 FEVIETSLTMADFEGA------DEIFTSGNYSKVLPVTRLEQR-------ELQAGP-VTA 279 Query: 364 RILSKLTD 371 + D Sbjct: 280 KARDLYMD 287 >1G2W-A nrPDB Length = 282 Score = 102 bits (253), Expect = 3e-22, Method: Composition-based stats. Identities = 54/317 (17%), Positives = 114/317 (35%), Gaps = 64/317 (20%) Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127 W I + + + + ++E +K + G +F N ++DR+Y SA + Sbjct: 5 W-NDQIVKDEEVKIDKEDRGYQFGDGVYEVVKVYNG-----EMFTVNEHIDRLYASAEKI 58 Query: 128 TLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVL 186 + + + K++ + + +LV+ ++ +Y + Sbjct: 59 RITIPYTKDKFHQLLHELVEKNELNT-----GHIY-------------------FQVTRG 94 Query: 187 LSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGG--------------NYGSSLF 232 SP F T PV + + R + K N ++ Sbjct: 95 TSPRAHQFPENTVKPVIIGYTKENPRPLENLEKGVKATFVEDIRWLRCDIKSLNLLGAVL 154 Query: 233 AQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRR 292 A+ EA + GC + + ++ +T + N+F + L T P + +IL G+TR Sbjct: 155 AKQEAHEKGCYEAI--LHRNNTVTSGSSSNVFGI-----KDGILYTHPANNMILKGITRD 207 Query: 293 CILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHI 352 ++ A++ V E T + ++ E+F + T + PV +I K I Sbjct: 208 VVIACANEI-NMPVKEIPFTTHE------ALKMDELFVTSTTSEITPVIEIDGKL----I 256 Query: 353 PTMENGPKLASRILSKL 369 + G + ++ + Sbjct: 257 RDGKVG-EWTRKLQKQF 272 >4PBC-A nrPDB Length = 316 Score = 89.5 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 47/300 (15%), Positives = 102/300 (34%), Gaps = 25/300 (8%) Query: 72 HIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPV 131 + PL + + ++E + + D F+ ++DR+ RS + + Sbjct: 27 ELVPLSEARVPVLDRGFIFGDGVYEVVPVY-AHDGAHVPFRIEQHLDRLARSLKKIGIDN 85 Query: 132 FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVG 191 + + V +A +Y++ T + +F + SP+ Sbjct: 86 PHDAAGWRALIERVVAANAEGLGDGNALVYLQVTRGVAKRGHAFPANAVPTVFAMTSPL- 144 Query: 192 PYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGE 251 S + R W D K G+ L AQ A + + + L E Sbjct: 145 -RLPSEEERAKGVRCVTAEDRRWLHC--DIKSISLLGNVLMAQ-HAAERDAFETIQLRDE 200 Query: 252 DHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYL 311 + +TE + N+++ EL PP IL G+ R +++ + R + Sbjct: 201 N--VTEGSSSNVWIV-----KNGELFAPPRSNKILEGI-RYALVEQLADECGIRFVAREI 252 Query: 312 TMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTD 371 + +L +A E+ + + PV+ + + + + + GP + + + Sbjct: 253 SEVELRSA------DEIMLTSATKEILPVTSL----DDLPVQGGKPGP-VFAALYDAYQR 301 >4TM5-A nrPDB Length = 311 Score = 84.8 bits (208), Expect = 6e-17, Method: Composition-based stats. Identities = 48/302 (15%), Positives = 103/302 (34%), Gaps = 28/302 (9%) Query: 72 HIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRL-FQPNLNMDRMYRSAVRATLP 130 + PL + + ++E + + + R F+ ++ R+ RS + + Sbjct: 27 ELVPLSEARVPVLDRGFIFGDGVYEVVPIY--AEGARRAPFRIAQHLARLARSLKKIGIA 84 Query: 131 VFDKEELLECIQ-QLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSP 189 E + +LV + + A +YI+ T + +F + SP Sbjct: 85 DPHDEAGWRALVARLVDANAAALGDGQHAIVYIQVTRGVAKRGHAFPANAVPTVFAMASP 144 Query: 190 VGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLY 249 + + + R W D K G+ L AQ A ++ + + L Sbjct: 145 LA--LPTDAQRAQGVHCVTAEDRRWLHC--DIKSVSLLGNVLMAQ-HAAEHDAAETIQL- 198 Query: 250 GEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSER 309 D +TE + N+++ EL PP IL G+ R +++ + + R Sbjct: 199 -RDGNVTEGSSSNVWIV-----KNGELIAPPRSNRILEGI-RYALVEELAEECGIRFVAR 251 Query: 310 YLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKL 369 + +L A E+ + + PV+ + + + + GP + + + Sbjct: 252 EINEAELRAA------DEILLTSATKEILPVTRL----DDLPVQGGRPGP-VFDALYAAY 300 Query: 370 TD 371 Sbjct: 301 QR 302 >4UUG-A nrPDB Length = 332 Score = 73.3 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 48/281 (17%), Positives = 93/281 (33%), Gaps = 52/281 (18%) Query: 109 RLFQPNLNMDRMYRSA--VRATLPVF------------DKEELLECIQQL-VKLDQEWVP 153 R F+ + ++ R+ S +R P+ K + + ++ V V Sbjct: 67 RFFRLDDHLQRILESCDKMRLKFPLALSSVKNILAEMVAKSGIRDAFVEVIVTRGLTGVR 126 Query: 154 YSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRA 213 S LY ++ P + V P L G ++ R Sbjct: 127 GSKPEDLYNNNIYLLVLPYIWVMAPENQLH-------------GGEAIITRTVR----RT 169 Query: 214 WKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGE 273 G +G EA+D G +L D +TE N+ L Sbjct: 170 PPGAFDPTIKNLQWGDLTKGLFEAMDRGA-TYPFLTDGDTNLTEGSGFNIVLV-----KN 223 Query: 274 EELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGT 333 + TP D +L G+TR+ ++D+A + + ++ + E+F T Sbjct: 224 GIIYTP--DRGVLRGITRKSVIDVAR-ANSIDIRLEVVPVEQAYHS------DEIFMCTT 274 Query: 334 ACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQY 374 A + P++ + + + + GP + +I ++ Y Sbjct: 275 AGGIMPITLLDGQP----VNDGQVGP-ITKKIWDGYWEMHY 310 >2Y4R-A nrPDB Length = 292 Score = 71.7 bits (174), Expect = 5e-13, Method: Composition-based stats. Identities = 58/311 (18%), Positives = 100/311 (32%), Gaps = 46/311 (14%) Query: 68 WEKPHIKPLQN----LSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123 + + H+ + L L Y LFE L G ++ R+ Sbjct: 17 YFQGHMLDWVDGRPAAELSVRDRGLAYGDGLFETLAVRAGTPRL-----LERHLARLEEG 71 Query: 124 AVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSL-GVKKPTKA- 181 R +P+ ++Q + + + + L G P +A Sbjct: 72 CRRLAIPLDTA-----ALRQELLAFCAALGDG------VAKLIVTRGEGLRGYAPPAEAS 120 Query: 182 -LLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240 + SP Y V L+A + G + N + A+ E D Sbjct: 121 PRRILSGSPRPAYPERHWQQGVRLFACRTRLAEQPLLAGLKHL--NRLEQVLARAEWSDA 178 Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300 G + L L ++ E NL L + L P L + GV R +L+ A Sbjct: 179 GHAEGLMLD-VHERVVEGVFSNLLLVL-----DGTLVAPDLRRCGVAGVMRAELLERAEG 232 Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360 G ++ R ++M +L TA E+F + + PV + + P E Sbjct: 233 IG-VPLAIRDVSMAELATA------DEVFLCNSQFGIWPVRAL----DEHVWPVGE---- 277 Query: 361 LASRILSKLTD 371 L ++ +L D Sbjct: 278 LTRKLQDQLRD 288 >3SNO-A nrPDB Length = 315 Score = 55.2 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 57/284 (20%), Positives = 95/284 (33%), Gaps = 36/284 (12%) Query: 87 ALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVK 146 AL +FE L G + + +R SA LP E+ + Q ++ Sbjct: 42 ALTRGDGIFETLLIRDGHACNV-----RRHGERFKASAALLGLPEPILEDWEKATQMGIE 96 Query: 147 ----------LDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKAL-LFVLLSPVGPYFS 195 W +S + ++ P K + + V+ S G Sbjct: 97 SWYSHPNAGEASCTWTLSRGRSSTGLASGWLTITPVSSDKLAQREHGVSVMTSSRGYSID 156 Query: 196 SGTFNPVSLWAN--PKYVRA-WKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGED 252 +G K R T K Y +++ A A NG V++ G+ Sbjct: 157 TGLPGIGKATRGELSKVERTPAPWLTVGAKTLA-YAANMAALRYAKSNGFDDVIFTDGDR 215 Query: 253 HQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLT 312 + E T + + +++ TP G ILPG T+ + A + G ++ E+ L+ Sbjct: 216 --VLEGATSTVVSF-----KGDKIRTPSPGGDILPGTTQAALFAHATEKG-WRCKEKDLS 267 Query: 313 MDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTME 356 +DDL A V + G PV G + P E Sbjct: 268 IDDLFGADSVWLVSSVRG--------PVRVTRLDGHKLRKPDNE 303 >4K6N-A nrPDB Length = 383 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 46/139 (33%), Gaps = 16/139 (11%) Query: 194 FSSGTFNPVSLWANPKYVRAWKGGTGD-CKMGGNYGSSLFAQCEAVDNGCQQVLWLYGED 252 ++ F + Y RA + G+ +S +QCE + + Sbjct: 251 LNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCE---------ILFSNKS 301 Query: 253 HQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLT 312 + E N+ + + +G ++ TP L L G R +L L + E + Sbjct: 302 GLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGL------IEEGDID 355 Query: 313 MDDLTTALEGNRVREMFGS 331 + LT E + G Sbjct: 356 IGSLTVGNEVLLFNGVMGC 374 >2V2T-A nrPDB Length = 288 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 22/43 (51%) Query: 120 MYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYI 162 ++R + PV+DK+ ++ ++++E P + LY+ Sbjct: 169 LHRMDPILSEPVYDKKSTNTSELRICRINKESGPCTGGEELYL 211 >5T49-A nrPDB Length = 785 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 55/165 (33%), Gaps = 25/165 (15%) Query: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVP---YSTSASLYIRPTFIGTEPSLGVKK 177 + SA R F ++ ++ + DQEW + L IR + L Sbjct: 454 HSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYL 513 Query: 178 PTKALLFVLLSPVG-PYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCE 236 G F +G + ++ + + AW + GN + Sbjct: 514 RMFDPYSGNSWADGLATFDAGN----NQESSSEAMHAWTNVILWAEATGN---------K 560 Query: 237 AVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPL 281 A+ + ++L TE+ +N + + ++++ E P + Sbjct: 561 ALR---DRAIYL-----YTTEMSAINEYFFDVHQEIFPEEYGPEI 597 >5FXF-A nrPDB Length = 526 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 8/51 (15%), Positives = 19/51 (37%), Gaps = 2/51 (3%) Query: 26 KAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPL 76 +A++ I+ +L + +G T + L + + F W + Sbjct: 447 EAREEILQMTKVLVREA--AEAGYGEYRTHNALMDDVMATFNWGDGALLKF 495 >1QNO-A nrPDB Length = 344 Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 20/60 (33%), Gaps = 5/60 (8%) Query: 36 TILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALH--YAVE 93 T + +L FG T H+ W + + W I+ L G + Y + Sbjct: 224 TDFAKNVQIKSLDFG---TFHLYPDSWGTNYTWGNGWIQTHAAACLAAGKPCVFEEYGAQ 280 >6ED1-A nrPDB Length = 879 Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 18/47 (38%), Gaps = 2/47 (4%) Query: 255 ITEVGTMNLFLYWINEDGEEELATPPLDG--IILPGVTRRCILDLAH 299 I EVG NL ++ PP+ G I G+ RR L Sbjct: 133 ICEVGKENLLAVKVDNSSSLGEILPPVSGDFSIFGGIYRRVFLQWTE 179 >6D8K-A nrPDB Length = 597 Score = 29.4 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 10/75 (13%) Query: 53 FTDHMLTVEWSSEFGWEKP----------HIKPLQNLSLHPGSSALHYAVELFEGLKAFR 102 FT + V + GW P + P + L + Y E + + Sbjct: 462 FTSQLDVVAVNKYMGWYHPWPIEPENAVWEVIPDKPLIISEFGGEALYGQSGDENVASSW 521 Query: 103 GVDNKIRLFQPNLNM 117 + + RL++ N+ M Sbjct: 522 SEEYQARLYRDNIRM 536 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.124 0.322 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,399,781 Number of Sequences: 36641 Number of extensions: 558010 Number of successful extensions: 1519 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1355 Number of HSP's gapped (non-prelim): 51 length of query: 386 length of database: 10,336,785 effective HSP length: 99 effective length of query: 287 effective length of database: 6,709,326 effective search space: 1925576562 effective search space used: 1925576562 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)