BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P54687
(386 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
2COJ-A nrPDB 799 0.0
5BWR-A nrPDB 461 e-130
5U3F-A nrPDB 240 6e-64
3DTG-A nrPDB 225 3e-59
3UYY-A nrPDB 163 1e-40
4DQN-A nrPDB 161 4e-40
1IYD-A nrPDB 89 2e-18
4WHX-A nrPDB 73 2e-13
2EJ2-A nrPDB 72 4e-13
5CE8-A nrPDB 66 2e-11
6H65-A nrPDB 59 3e-09
6NST-A nrPDB 57 2e-08
3CSW-A nrPDB 40 0.002
6GKR-A nrPDB 38 0.009
3SNO-A nrPDB 31 0.93
2O59-A nrPDB 30 2.2
4N0Q-A nrPDB 28 6.6
>2COJ-A nrPDB
Length = 386
Score = 799 bits (2064), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 385/386 (99%), Positives = 385/386 (99%)
Query: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60
MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV
Sbjct: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60
Query: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120
EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM
Sbjct: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120
Query: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180
YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK
Sbjct: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180
Query: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240
ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN
Sbjct: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240
Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ
Sbjct: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK
Sbjct: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
Query: 361 LASRILSKLTDIQYGREESDWTIVLS 386
LASRILSKLTDIQYGREE DWTIVLS
Sbjct: 361 LASRILSKLTDIQYGREERDWTIVLS 386
>5BWR-A nrPDB
Length = 369
Score = 461 bits (1187), Expect = e-130, Method: Compositional matrix adjust.
Identities = 216/366 (59%), Positives = 273/366 (74%), Gaps = 2/366 (0%)
Query: 17 GSKEVVGTFKAKDLIVTPATILKEKPDPNN-LVFGTVFTDHMLTVEWSSEFGWEKPHIKP 75
GS +FKA DL + +KP P LVFG FTDHML VEW+ + GW +P I+P
Sbjct: 1 GSHMASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQP 59
Query: 76 LQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKE 135
QNL+LHP SS+LHY+++LFEG+KAF+G D ++RLF+P LNMDRM RSA+R LP FDK
Sbjct: 60 FQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKL 119
Query: 136 ELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFS 195
ELLECI++L+++D++WVP + SLY+RP IG EPSLGV +PT+ALLFV+L PVG YF
Sbjct: 120 ELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFP 179
Query: 196 SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQI 255
G+ PVSL A+P ++RAW GG G+ K+GGNYG ++ Q EA+ GC+QVLWLYG DHQ+
Sbjct: 180 GGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQL 239
Query: 256 TEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDD 315
TEVGTMN+F+YW +EDG EL TPPL+G+ILPGV R+ +LD+A WGEF+V ER +TM
Sbjct: 240 TEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQ 299
Query: 316 LTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375
L ALE RVRE+FGSGTAC VCPV ILYK +HIPTMENGP+L R +L +IQYG
Sbjct: 300 LLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYG 359
Query: 376 REESDW 381
+W
Sbjct: 360 IRAHEW 365
>5U3F-A nrPDB
Length = 368
Score = 240 bits (613), Expect = 6e-64, Method: Compositional matrix adjust.
Identities = 132/346 (38%), Positives = 188/346 (54%), Gaps = 6/346 (1%)
Query: 32 VTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYA 91
V PAT + + FG TDHM++++++ GW + P + L P + LHYA
Sbjct: 14 VNPATDAQRESMLREPGFGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHYA 73
Query: 92 VELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEW 151
E+FEGLKA+R D I F+ + N R+ SA R +P +E ++QL+ +D+ W
Sbjct: 74 QEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAW 133
Query: 152 VPYSTSA-SLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKY 210
VP + +LY+RP TEP LGV+ T+ ++ SP G YF G PVS+W + +Y
Sbjct: 134 VPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG-IAPVSVWVSTEY 192
Query: 211 VRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWIN 269
VRA GGTG K GGNY +SL AQ EA +NGC QV+WL E I E+G MN+F + +
Sbjct: 193 VRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF-FVLG 251
Query: 270 EDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMF 329
G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F
Sbjct: 252 SGGSARLVTPELSGSLLPGITRDSLLQLAIDAG-FAVEERRIDIDEWQKKAAAGEITEVF 310
Query: 330 GSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375
GTA V+ PV+ + + I + G ++ + LT IQ G
Sbjct: 311 ACGTAAVITPVARVRHGASEFRIADGQPG-EVTMALRDTLTGIQRG 355
>3DTG-A nrPDB
Length = 372
Score = 225 bits (573), Expect = 3e-59, Method: Compositional matrix adjust.
Identities = 133/345 (38%), Positives = 188/345 (54%), Gaps = 6/345 (1%)
Query: 33 TPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAV 92
PAT + N FG +TDHM++++++ + GW + P + L P + LHY
Sbjct: 19 NPATDAVRESILANPGFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQ 78
Query: 93 ELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV 152
E+FEGLKA+R D I F+P N R+ SA R +P +E +E ++QL+ +D++WV
Sbjct: 79 EIFEGLKAYRWADGSIVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWV 138
Query: 153 -PYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYV 211
P SLY+RP I TEP LGV+ + ++ SP G YF G PVS+W + +YV
Sbjct: 139 PPAGGEESLYLRPFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGG-IKPVSVWLSHEYV 197
Query: 212 RAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWINE 270
RA GGTG K GGNY +SL AQ +A + GC QV+WL E + E+G MNLF +
Sbjct: 198 RASPGGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVF-GS 256
Query: 271 DGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFG 330
G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F
Sbjct: 257 GGSARLVTPELSGSLLPGITRDSLLQLATDAG-FAVEERKIDVDEWQKKAGAGEITEVFA 315
Query: 331 SGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375
GTA V+ PVS + + I + G ++ + LT IQ G
Sbjct: 316 CGTAAVITPVSHVKHHDGEFTIADGQPG-EITMALRDTLTGIQRG 359
>3UYY-A nrPDB
Length = 358
Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust.
Identities = 112/340 (32%), Positives = 168/340 (49%), Gaps = 17/340 (5%)
Query: 43 DPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFR 102
D + L F + TD W + W+ + + L GS+ALHY + FEGLKA+R
Sbjct: 25 DWSTLGFSYIRTDLRYLAHWK-DGEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYR 83
Query: 103 GVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSASLY 161
D I LF+P+ N RM S R +P E+ ++ Q+V+ ++ ++ PY T SLY
Sbjct: 84 CADGSINLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLY 143
Query: 162 IRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDC 221
+RP IG ++GV+ + + V PVGPYF G P + + Y RA GTG
Sbjct: 144 LRPFVIGVGDNIGVRTAPEFIFSVFCVPVGPYFKGG-LTPTNFITS-DYDRAAPHGTGAA 201
Query: 222 KMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELATPP 280
K+GGNY +SL EA V++L H I E G N F I +DG++ + P
Sbjct: 202 KVGGNYAASLLPGYEAKKRDFADVIYLDPATHTTIEEAGAANFFA--ITQDGQKFVT--P 257
Query: 281 LDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPV 340
ILP +T+ +L LA +V E + +D+L + E GTA V+ P+
Sbjct: 258 QSPSILPSITKYSLLWLAEHRLGLEVEEGDIRIDEL------GKFSEAGACGTAAVITPI 311
Query: 341 SDILYKGETIHIPTMENGP-KLASRILSKLTDIQYGREES 379
I + G+ H+ E+ P + R+ +L IQYG +E+
Sbjct: 312 GGIQH-GDDFHVFYSESEPGPVTRRLYDELVGIQYGDKEA 350
>4DQN-A nrPDB
Length = 345
Score = 161 bits (408), Expect = 4e-40, Method: Compositional matrix adjust.
Identities = 109/330 (33%), Positives = 166/330 (50%), Gaps = 21/330 (6%)
Query: 53 FTDHMLTVEWSSEFG---WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIR 109
F H L + S + W+ + L + S ALHY E FEGLKA+R D ++
Sbjct: 16 FEYHKLPFRYISYYKDGKWDDGKLTEDATLHISESSPALHYGQEAFEGLKAYRTKDGSVQ 75
Query: 110 LFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSASLYIRPTFIG 168
LF+PN+N +R+ R+A R +P ++ ++ +Q+V+ ++E+V PY T A+LY+RP IG
Sbjct: 76 LFRPNMNAERLQRTADRLLMPQVPTDKFIDAAKQVVRANEEYVPPYGTGATLYLRPLLIG 135
Query: 169 TEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYG 228
+GV + + + PVG YF G P + Y RA GTG K+GGNY
Sbjct: 136 VGDVIGVHPADEYIFTIFAMPVGNYFKGG-LAPTNFLIQDDYDRAAPHGTGAAKVGGNYA 194
Query: 229 SSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELATPPLDGIILP 287
+SL A + V++L H +I EVG+ N F I +D E PL ILP
Sbjct: 195 ASLLPGKVAHERQFSDVIYLDPATHTKIEEVGSANFF--GITKDNE---FITPLSPSILP 249
Query: 288 GVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKG 347
VT+ +L LA K E + +D+L ++ E GTA V+ P+ + + G
Sbjct: 250 SVTKYSLLYLAEHRFGMKAIEGDVCVDEL------DKFVEAGACGTAAVISPIGGVQH-G 302
Query: 348 ETIHI--PTMENGPKLASRILSKLTDIQYG 375
+ H+ E GP + ++ +LT IQ+G
Sbjct: 303 DDFHVFYSETEVGP-VTHKLYDELTGIQFG 331
>1IYD-A nrPDB
Length = 309
Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 91/328 (27%), Positives = 142/328 (43%), Gaps = 42/328 (12%)
Query: 64 SEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123
+++ W + ++ +H S ALHY +FEG++ + + +F+ +M R++ S
Sbjct: 6 ADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV-VFRHREHMQRLHDS 64
Query: 124 AVRATLPVFDK-EELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKAL 182
A PV +EL+E + +++ + S YIRP + +GV P
Sbjct: 65 AKIYRFPVSQSIDELMEACRDVIRKNN-------LTSAYIRPLIFVGDVGMGVNPPAGYS 117
Query: 183 LFVLLS--PVGPYFSS-----GTFNPVSLW--ANPKYVRAWKGGTGDCKMGGNYGSSLFA 233
V+++ P G Y + G VS W A P + K GGNY SSL
Sbjct: 118 TDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPT------AAKAGGNYLSSLLV 171
Query: 234 QCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRC 293
EA +G Q+ + L + I+E NLF E + L TPP LPG+TR
Sbjct: 172 GSEARRHGYQEGIAL-DVNGYISEGAGENLF-----EVKDGVLFTPPFTSSALPGITRDA 225
Query: 294 ILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIP 353
I+ LA + G +V E+ L+ + L A E+F SGTA + PV + + I +
Sbjct: 226 IIKLAKELG-IEVREQVLSRESLYLA------DEVFMSGTAAEITPVRSV----DGIQVG 274
Query: 354 TMENGPKLASRILSKLTDIQYGREESDW 381
GP + RI + G E W
Sbjct: 275 EGRCGP-VTKRIQQAFFGLFTGETEDKW 301
>4WHX-A nrPDB
Length = 311
Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 90/331 (27%), Positives = 145/331 (43%), Gaps = 55/331 (16%)
Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127
W + ++ +H + LHY + +FEG++A++ D +F+ + R+ SA
Sbjct: 15 WMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNSAKIF 74
Query: 128 TLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRP-TFIGTEPSLGVKKPTKALLFVL 186
+ V +E LE Q+ V V + S Y+RP +IG+E LGV + +
Sbjct: 75 QMDVPFDQETLEAAQRDV------VRENKLESCYLRPIIWIGSEK-LGVSAKGNTIHVAI 127
Query: 187 LS-PVGPYF-------------SSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLF 232
+ P G Y SS T + V N VRA K G Y +S+
Sbjct: 128 AAWPWGAYLGEEGLAKGIRVKTSSFTRHHV----NVSMVRA--------KASGWYVNSIL 175
Query: 233 AQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRR 292
A EA +G + L L D ++E N FL +N +L TP L L G+TR
Sbjct: 176 ANQEATADGYDEAL-LLDVDGYVSEGSGENFFL--VNRG---KLYTPDL-ASCLDGITRD 228
Query: 293 CILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHI 352
++ LA + G +V E+ +T D++ TA E F +GTA V P+ ++ + I
Sbjct: 229 TVITLAKEAG-IEVIEKRITRDEVYTA------DEAFFTGTAAEVTPIREL----DNRTI 277
Query: 353 PTMENGPKLASRILSKLTDIQYGR--EESDW 381
GP + ++ S D+ G+ + +DW
Sbjct: 278 GGGARGP-ITEKLQSAFFDVVNGKSAKHADW 307
>2EJ2-A nrPDB
Length = 308
Score = 72.0 bits (175), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 83/272 (30%), Positives = 118/272 (43%), Gaps = 38/272 (13%)
Query: 85 SSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSA--VRATLPVFDKEELLECIQ 142
S ALHY +FEG++A+ +F+ ++ R Y SA +R +P F EEL E I+
Sbjct: 26 SHALHYGTSVFEGIRAYETAKGPA-IFRLKEHVKRFYNSAKVLRMEIP-FAPEELEEAIK 83
Query: 143 QLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKK--PTKALLFVLLSPVGPYFS----- 195
++V+ + S YIRP +LGV A + V G Y
Sbjct: 84 EVVRRN-------GYRSCYIRPLAWMGAKALGVNPLPNNPAEVMVAAWEWGAYLGEEAVR 136
Query: 196 SGTFNPVSLWAN-PKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQ 254
G S WA P V G K+GGNY +S A+ EAV G + L L E+
Sbjct: 137 KGARLITSSWARFPANVM-----PGKAKVGGNYVNSALAKMEAVAAGADEAL-LLDEEGY 190
Query: 255 ITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMD 314
+ E NLF DG + + L G+TR ++ +A G ++V T D
Sbjct: 191 VAEGSGENLFFV---RDG---VIYALEHSVNLEGITRDSVIRIAKDLG-YEVQVVRATRD 243
Query: 315 DLTTALEGNRVREMFGSGTACVVCPVSDILYK 346
L A E+F +GTA V PVS I ++
Sbjct: 244 QLYMA------DEVFMTGTAAEVTPVSMIDWR 269
>5CE8-A nrPDB
Length = 307
Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 76/297 (25%), Positives = 130/297 (43%), Gaps = 35/297 (11%)
Query: 85 SSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPV-FDKEELLECIQQ 143
S +L+Y +FEG++A+ +N + +F+ +M+R+ RSA L V + EEL + + +
Sbjct: 33 SPSLNYGFGVFEGIRAYWNGEN-LYVFRLRDHMERLLRSAKIIGLDVPYTAEELSKAVVE 91
Query: 144 LVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVK-KPTKALLFVLLSPVGPYFS-SGTFNP 201
V+ + LYIRP ++P + + + +A + + P G Y G
Sbjct: 92 TVRAN------GFKEDLYIRPVAYISKPQISLDVRGLQASVAIAAIPFGKYLKVEGVRAA 145
Query: 202 VSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTM 261
V W K G Y +S+ A EA G + + L E ++ E
Sbjct: 146 VVSWRRVHTSMM----PVMAKATGIYLNSIMAAVEARARGYDEAIMLNAEG-KVVEGSGE 200
Query: 262 NLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALE 321
N+F+ L TPPL+ IL G+TR ++ +A G + E+ +T ++L A
Sbjct: 201 NIFIVR-----RGVLMTPPLEDGILEGITRETVISIAGDLG-IPLLEKSITREELYAA-- 252
Query: 322 GNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYGREE 378
E F GTA + P+ +I + ++ GP + +I I G+EE
Sbjct: 253 ----DEAFFVGTAAEITPIIEIDGR-------VLQRGP-ITQKIAETYRRIVLGKEE 297
>6H65-A nrPDB
Length = 317
Score = 59.3 bits (142), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 72/330 (21%), Positives = 140/330 (42%), Gaps = 63/330 (19%)
Query: 65 EFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDN-KIRLFQPNLNMDRMYRS 123
+GW P SLH + A + LFEG++A+ + ++ +F+ + ++ R+ +S
Sbjct: 14 RYGWMNGQCIPWDQCSLHVSTQAAFFGASLFEGVRAYWNAEREQLYVFRLDEHLRRLEQS 73
Query: 124 A----VRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTF-IGTEPSLGVKKP 178
A ++ ++P+ D + + + +L++ ++ + + LY+ F I +P
Sbjct: 74 AKMLRMKLSMPIAD---IRQGVLELLRANE----FRSDVHLYVASYFGINHDPD------ 120
Query: 179 TKALLFVLLSPVGPYFSSGTFN--------PVSLWANPKYVRAWKGGTGDC-----KMGG 225
P+ P +G + P+ + +W+ + D K+G
Sbjct: 121 ----------PLFPTDDTGVYVTGTAVSRLPLVHTGISACMSSWRRISDDSVPPRIKIGA 170
Query: 226 NYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGII 285
NY +S AQ EA NG + L +++E L + DG + +PP+ I
Sbjct: 171 NYQNSRLAQTEARVNGYHTSV-LLNSRGKVSETPGACLLMV---RDGR--VISPPVTADI 224
Query: 286 LPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY 345
L VTR+ ++ L+ + V ER + +L A E+F GT + PV+ I
Sbjct: 225 LESVTRKTLMSLSEAELDSPVIERDMDRTELYIA------EEVFLCGTIAEILPVTTI-- 276
Query: 346 KGETIHIPTMENGPKLASRILSKLTDIQYG 375
+ I + E GP + +L ++ +G
Sbjct: 277 --DRIQVGDGEVGP-----VTRRLQELYFG 299
>6NST-A nrPDB
Length = 307
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 66/258 (25%), Positives = 114/258 (44%), Gaps = 27/258 (10%)
Query: 90 YAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPV-FDKEELLECIQQLVKLD 148
Y + +FEG++A+ +F+ + DR++ SA + + + ++E+ E + V+ +
Sbjct: 33 YGMGVFEGVRAY-DTPQGTAIFRLQAHTDRLFDSAHIMNMQIPYSRDEINEATRAAVREN 91
Query: 149 QEWVPYSTSASLYIRP-TFIGTEPSLGVKKP-TKALLFVLLSPVGPYFSSGTFNPVSLWA 206
S YIRP F G+E +G++ K + + G Y
Sbjct: 92 N-------LESAYIRPMVFYGSE-GMGLRASGLKVHVIIAAWSWGAYMGEEALQQGIKVR 143
Query: 207 NPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFL 265
+ R K G Y +S+ A EA+ G + + L E + + E N+F
Sbjct: 144 TSSFTRHHVNISMTRAKSNGAYINSMLALQEAISGGADEAMMLDPEGY-VAEGSGENIF- 201
Query: 266 YWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRV 325
I +DG + TP + L G+TR IL LA + G FK+ E+ +T D++ A
Sbjct: 202 --IIKDG--VIYTPEVTA-CLNGITRNTILTLAAEHG-FKLVEKRITRDEVYIA------ 249
Query: 326 REMFGSGTACVVCPVSDI 343
E F +GTA V P+ ++
Sbjct: 250 DEAFFTGTAAEVTPIREV 267
>3CSW-A nrPDB
Length = 285
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 39/110 (35%), Positives = 54/110 (49%), Gaps = 15/110 (13%)
Query: 231 LFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVT 290
+ A+ E VD C V+ L G + Q+ E N+FL E +L TP LD IL G+T
Sbjct: 153 VLARREIVD--CYDVI-LLGLNGQVCEGSFSNVFLV-----KEGKLITPSLDSGILDGIT 204
Query: 291 RRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPV 340
R ++ LA E V ER + + +L A EMF + T+ V PV
Sbjct: 205 RENVIKLAKSL-EIPVEERVVWVWELFEA------DEMFLTHTSAGVVPV 247
>6GKR-A nrPDB
Length = 316
Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 35/122 (28%), Positives = 51/122 (41%), Gaps = 12/122 (9%)
Query: 222 KMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPL 281
K NY +S A EA NG L+L E G+ F+ + +L TP +
Sbjct: 160 KALANYRNSQLASSEAAMNGYDTALFLNPEGKVAEGTGSCVFFV------RKGKLITPDI 213
Query: 282 DGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVS 341
IL +TR ++ LA + +V ER +D T L E F GT + P++
Sbjct: 214 TSGILESITRDTVIHLAREVLGLEVEER--VVDRTETYLAD----EAFLCGTHAEITPIA 267
Query: 342 DI 343
I
Sbjct: 268 SI 269
>3SNO-A nrPDB
Length = 315
Score = 30.8 bits (68), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 227 YGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIIL 286
Y +++ A A NG V++ G+ ++ E T + + +++ TP G IL
Sbjct: 190 YAANMAALRYAKSNGFDDVIFTDGD--RVLEGATSTVVSF-----KGDKIRTPSPGGDIL 242
Query: 287 PGVTRRCILDLAHQWGEFKVSERYLTMDDL 316
PG T+ + A + G ++ E+ L++DDL
Sbjct: 243 PGTTQAALFAHATEKG-WRCKEKDLSIDDL 271
>2O59-A nrPDB
Length = 659
Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 288 GVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY-- 345
V R+C+++L G+F R+L T L G++ R+ GT V D L
Sbjct: 418 AVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL-GSKERDEENDGTPLPVVAKGDELLCE 476
Query: 346 KGETIHIPTMENGPKLASRILSKLTDIQYGREESDWTIVL 385
KGE + T + +LS +T I ++ D +L
Sbjct: 477 KGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKIL 516
>4N0Q-A nrPDB
Length = 354
Score = 28.1 bits (61), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 24/48 (50%)
Query: 322 GNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKL 369
G+ ++ + G T V PVSD+L + + + GP L +R L +
Sbjct: 75 GDGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENV 122
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
2COJ-A nrPDB 594 e-170
5BWR-A nrPDB 498 e-141
5U3F-A nrPDB 429 e-121
3DTG-A nrPDB 418 e-117
3UYY-A nrPDB 383 e-107
4DQN-A nrPDB 367 e-102
1IYD-A nrPDB 317 7e-87
4WHX-A nrPDB 312 2e-85
5CE8-A nrPDB 272 2e-73
6NST-A nrPDB 267 8e-72
6H65-A nrPDB 266 1e-71
2EJ2-A nrPDB 264 6e-71
3CSW-A nrPDB 123 1e-28
Sequences not found previously or not previously below threshold:
6GKR-A nrPDB 200 8e-52
5MQZ-A nrPDB 180 7e-46
5E25-A nrPDB 174 5e-44
4JXU-A nrPDB 107 9e-24
1G2W-A nrPDB 102 3e-22
4PBC-A nrPDB 89 2e-18
4TM5-A nrPDB 85 6e-17
4UUG-A nrPDB 73 2e-13
2Y4R-A nrPDB 72 5e-13
3SNO-A nrPDB 55 4e-08
4K6N-A nrPDB 39 0.003
2V2T-A nrPDB 31 1.4
5T49-A nrPDB 30 1.6
5FXF-A nrPDB 30 1.8
1QNO-A nrPDB 30 2.3
6ED1-A nrPDB 30 2.3
6D8K-A nrPDB 29 2.9
>2COJ-A nrPDB
Length = 386
Score = 594 bits (1530), Expect = e-170, Method: Composition-based stats.
Identities = 385/386 (99%), Positives = 385/386 (99%)
Query: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60
MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV
Sbjct: 1 MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV 60
Query: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120
EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM
Sbjct: 61 EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM 120
Query: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180
YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK
Sbjct: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK 180
Query: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240
ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN
Sbjct: 181 ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240
Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ
Sbjct: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK
Sbjct: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
Query: 361 LASRILSKLTDIQYGREESDWTIVLS 386
LASRILSKLTDIQYGREE DWTIVLS
Sbjct: 361 LASRILSKLTDIQYGREERDWTIVLS 386
>5BWR-A nrPDB
Length = 369
Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats.
Identities = 215/366 (58%), Positives = 272/366 (74%), Gaps = 2/366 (0%)
Query: 17 GSKEVVGTFKAKDLIVTPATILKEKPDPNNL-VFGTVFTDHMLTVEWSSEFGWEKPHIKP 75
GS +FKA DL + +KP P VFG FTDHML VEW+ + GW +P I+P
Sbjct: 1 GSHMASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDK-GWGQPRIQP 59
Query: 76 LQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKE 135
QNL+LHP SS+LHY+++LFEG+KAF+G D ++RLF+P LNMDRM RSA+R LP FDK
Sbjct: 60 FQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKL 119
Query: 136 ELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFS 195
ELLECI++L+++D++WVP + SLY+RP IG EPSLGV +PT+ALLFV+L PVG YF
Sbjct: 120 ELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFP 179
Query: 196 SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQI 255
G+ PVSL A+P ++RAW GG G+ K+GGNYG ++ Q EA+ GC+QVLWLYG DHQ+
Sbjct: 180 GGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQL 239
Query: 256 TEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDD 315
TEVGTMN+F+YW +EDG EL TPPL+G+ILPGV R+ +LD+A WGEF+V ER +TM
Sbjct: 240 TEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQ 299
Query: 316 LTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375
L ALE RVRE+FGSGTAC VCPV ILYK +HIPTMENGP+L R +L +IQYG
Sbjct: 300 LLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYG 359
Query: 376 REESDW 381
+W
Sbjct: 360 IRAHEW 365
>5U3F-A nrPDB
Length = 368
Score = 429 bits (1103), Expect = e-121, Method: Composition-based stats.
Identities = 132/346 (38%), Positives = 187/346 (54%), Gaps = 6/346 (1%)
Query: 32 VTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYA 91
V PAT + + FG TDHM++++++ GW + P + L P + LHYA
Sbjct: 14 VNPATDAQRESMLREPGFGKYHTDHMVSIDYAEGRGWHNARVIPYGPIELDPSAIVLHYA 73
Query: 92 VELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEW 151
E+FEGLKA+R D I F+ + N R+ SA R +P +E ++QL+ +D+ W
Sbjct: 74 QEVFEGLKAYRWADGSIVSFRADANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAW 133
Query: 152 VPYSTS-ASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKY 210
VP + +LY+RP TEP LGV+ T+ ++ SP G YF G PVS+W + +Y
Sbjct: 134 VPGAGGEEALYLRPFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG-IAPVSVWVSTEY 192
Query: 211 VRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWIN 269
VRA GGTG K GGNY +SL AQ EA +NGC QV+WL E I E+G MN+F +
Sbjct: 193 VRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIFFV-LG 251
Query: 270 EDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMF 329
G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F
Sbjct: 252 SGGSARLVTPELSGSLLPGITRDSLLQLAIDAG-FAVEERRIDIDEWQKKAAAGEITEVF 310
Query: 330 GSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375
GTA V+ PV+ + + I + G ++ + LT IQ G
Sbjct: 311 ACGTAAVITPVARVRHGASEFRIADGQPG-EVTMALRDTLTGIQRG 355
>3DTG-A nrPDB
Length = 372
Score = 418 bits (1074), Expect = e-117, Method: Composition-based stats.
Identities = 133/345 (38%), Positives = 188/345 (54%), Gaps = 6/345 (1%)
Query: 33 TPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAV 92
PAT + N FG +TDHM++++++ + GW + P + L P + LHY
Sbjct: 19 NPATDAVRESILANPGFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLHYGQ 78
Query: 93 ELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV 152
E+FEGLKA+R D I F+P N R+ SA R +P +E +E ++QL+ +D++WV
Sbjct: 79 EIFEGLKAYRWADGSIVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWV 138
Query: 153 -PYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYV 211
P SLY+RP I TEP LGV+ + ++ SP G YF G PVS+W + +YV
Sbjct: 139 PPAGGEESLYLRPFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGG-IKPVSVWLSHEYV 197
Query: 212 RAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYG-EDHQITEVGTMNLFLYWINE 270
RA GGTG K GGNY +SL AQ +A + GC QV+WL E + E+G MNLF +
Sbjct: 198 RASPGGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVF-GS 256
Query: 271 DGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFG 330
G L TP L G +LPG+TR +L LA G F V ER + +D+ + E+F
Sbjct: 257 GGSARLVTPELSGSLLPGITRDSLLQLATDAG-FAVEERKIDVDEWQKKAGAGEITEVFA 315
Query: 331 SGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQYG 375
GTA V+ PVS + + I + G ++ + LT IQ G
Sbjct: 316 CGTAAVITPVSHVKHHDGEFTIADGQPG-EITMALRDTLTGIQRG 359
>3UYY-A nrPDB
Length = 358
Score = 383 bits (983), Expect = e-107, Method: Composition-based stats.
Identities = 112/340 (32%), Positives = 167/340 (49%), Gaps = 17/340 (5%)
Query: 43 DPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFR 102
D + L F + TD W + W+ + + L GS+ALHY + FEGLKA+R
Sbjct: 25 DWSTLGFSYIRTDLRYLAHWK-DGEWDAGTLTEDNQIHLAEGSTALHYGQQCFEGLKAYR 83
Query: 103 GVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSASLY 161
D I LF+P+ N RM S R +P E+ ++ Q+V+ ++ ++ PY T SLY
Sbjct: 84 CADGSINLFRPDQNAARMRMSCRRLLMPELSDEQFIDACLQVVRANEHFLPPYGTGGSLY 143
Query: 162 IRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDC 221
+RP IG ++GV+ + + V PVGPYF G P + Y RA GTG
Sbjct: 144 LRPFVIGVGDNIGVRTAPEFIFSVFCVPVGPYFKGG-LTPTNFI-TSDYDRAAPHGTGAA 201
Query: 222 KMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELATPP 280
K+GGNY +SL EA V++L H I E G N F I +DG++ + P
Sbjct: 202 KVGGNYAASLLPGYEAKKRDFADVIYLDPATHTTIEEAGAANFFA--ITQDGQKFV--TP 257
Query: 281 LDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPV 340
ILP +T+ +L LA +V E + +D+L + E GTA V+ P+
Sbjct: 258 QSPSILPSITKYSLLWLAEHRLGLEVEEGDIRIDEL------GKFSEAGACGTAAVITPI 311
Query: 341 SDILYKGETIHIPTMENGP-KLASRILSKLTDIQYGREES 379
I + G+ H+ E+ P + R+ +L IQYG +E+
Sbjct: 312 GGIQH-GDDFHVFYSESEPGPVTRRLYDELVGIQYGDKEA 350
>4DQN-A nrPDB
Length = 345
Score = 367 bits (941), Expect = e-102, Method: Composition-based stats.
Identities = 112/344 (32%), Positives = 171/344 (49%), Gaps = 25/344 (7%)
Query: 43 DPNNLVFGTVFTDHMLTVEWSSEFG---WEKPHIKPLQNLSLHPGSSALHYAVELFEGLK 99
D NL F H L + S + W+ + L + S ALHY E FEGLK
Sbjct: 10 DWKNLGF----EYHKLPFRYISYYKDGKWDDGKLTEDATLHISESSPALHYGQEAFEGLK 65
Query: 100 AFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWV-PYSTSA 158
A+R D ++LF+PN+N +R+ R+A R +P ++ ++ +Q+V+ ++E+V PY T A
Sbjct: 66 AYRTKDGSVQLFRPNMNAERLQRTADRLLMPQVPTDKFIDAAKQVVRANEEYVPPYGTGA 125
Query: 159 SLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGT 218
+LY+RP IG +GV + + + PVG YF G P + Y RA GT
Sbjct: 126 TLYLRPLLIGVGDVIGVHPADEYIFTIFAMPVGNYFKGG-LAPTNFLIQDDYDRAAPHGT 184
Query: 219 GDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDH-QITEVGTMNLFLYWINEDGEEELA 277
G K+GGNY +SL A + V++L H +I EVG+ N F I +D E
Sbjct: 185 GAAKVGGNYAASLLPGKVAHERQFSDVIYLDPATHTKIEEVGSANFF--GITKDNE---F 239
Query: 278 TPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVV 337
PL ILP VT+ +L LA K E + +D+L ++ E GTA V+
Sbjct: 240 ITPLSPSILPSVTKYSLLYLAEHRFGMKAIEGDVCVDEL------DKFVEAGACGTAAVI 293
Query: 338 CPVSDILYKGETIHI--PTMENGPKLASRILSKLTDIQYGREES 379
P+ + + G+ H+ E GP + ++ +LT IQ+G ++
Sbjct: 294 SPIGGVQH-GDDFHVFYSETEVGP-VTHKLYDELTGIQFGDVKA 335
>1IYD-A nrPDB
Length = 309
Score = 317 bits (811), Expect = 7e-87, Method: Composition-based stats.
Identities = 86/323 (26%), Positives = 136/323 (42%), Gaps = 30/323 (9%)
Query: 63 SSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYR 122
+++ W + ++ +H S ALHY +FEG++ + + +F+ +M R++
Sbjct: 5 KADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPV-VFRHREHMQRLHD 63
Query: 123 SAVRATLPVFDK-EELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKA 181
SA PV +EL+E + +++ + S YIRP + +GV P
Sbjct: 64 SAKIYRFPVSQSIDELMEACRDVIRKNN-------LTSAYIRPLIFVGDVGMGVNPPAGY 116
Query: 182 L--LFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAV 238
+ + P G Y + + RA K GGNY SSL EA
Sbjct: 117 STDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAKAGGNYLSSLLVGSEAR 176
Query: 239 DNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLA 298
+G Q+ + L + I+E NLF E + L TPP LPG+TR I+ LA
Sbjct: 177 RHGYQEGIALD-VNGYISEGAGENLF-----EVKDGVLFTPPFTSSALPGITRDAIIKLA 230
Query: 299 HQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENG 358
+ G +V E+ L+ + L A E+F SGTA + PV + + I + G
Sbjct: 231 KELG-IEVREQVLSRESLYLA------DEVFMSGTAAEITPVRSV----DGIQVGEGRCG 279
Query: 359 PKLASRILSKLTDIQYGREESDW 381
P + RI + G E W
Sbjct: 280 P-VTKRIQQAFFGLFTGETEDKW 301
>4WHX-A nrPDB
Length = 311
Score = 312 bits (798), Expect = 2e-85, Method: Composition-based stats.
Identities = 79/322 (24%), Positives = 130/322 (40%), Gaps = 29/322 (9%)
Query: 64 SEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123
W + ++ +H + LHY + +FEG++A++ D +F+ + R+ S
Sbjct: 11 DGKIWMDGKLIEWRDAKIHVLTHTLHYGMGVFEGVRAYKTADGGTAIFRLKEHTKRLLNS 70
Query: 124 AVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALL 183
A + V +E LE Q+ V V + S Y+RP LGV +
Sbjct: 71 AKIFQMDVPFDQETLEAAQRDV------VRENKLESCYLRPIIWIGSEKLGVSAKGNTIH 124
Query: 184 F-VLLSPVGPYFSSGTFNPVSLWANPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAVDNG 241
+ P G Y + R K G Y +S+ A EA +G
Sbjct: 125 VAIAAWPWGAYLGEEGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEATADG 184
Query: 242 CQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQW 301
+ L L D ++E N FL +L TP L L G+TR ++ LA +
Sbjct: 185 YDEAL-LLDVDGYVSEGSGENFFLV-----NRGKLYTPDL-ASCLDGITRDTVITLAKEA 237
Query: 302 GEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKL 361
G +V E+ +T D++ TA E F +GTA V P+ ++ + I GP +
Sbjct: 238 G-IEVIEKRITRDEVYTA------DEAFFTGTAAEVTPIREL----DNRTIGGGARGP-I 285
Query: 362 ASRILSKLTDIQYGR--EESDW 381
++ S D+ G+ + +DW
Sbjct: 286 TEKLQSAFFDVVNGKSAKHADW 307
>5CE8-A nrPDB
Length = 307
Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats.
Identities = 77/314 (24%), Positives = 134/314 (42%), Gaps = 35/314 (11%)
Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127
W + + + S +L+Y +FEG++A+ +N + +F+ +M+R+ RSA
Sbjct: 16 WLDGRLVDEEEAKVTVLSPSLNYGFGVFEGIRAYWNGEN-LYVFRLRDHMERLLRSAKII 74
Query: 128 TLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVK-KPTKALLFV 185
L V + EEL + + + V+ + LYIRP ++P + + + +A + +
Sbjct: 75 GLDVPYTAEELSKAVVETVRAN------GFKEDLYIRPVAYISKPQISLDVRGLQASVAI 128
Query: 186 LLSPVGPYFS-SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQ 244
P G Y G V W K G Y +S+ A EA G +
Sbjct: 129 AAIPFGKYLKVEGVRAAVVSWRRVHTSMM----PVMAKATGIYLNSIMAAVEARARGYDE 184
Query: 245 VLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEF 304
+ L E ++ E N+F+ L TPPL+ IL G+TR ++ +A G
Sbjct: 185 AIMLNAE-GKVVEGSGENIFIVR-----RGVLMTPPLEDGILEGITRETVISIAGDLG-I 237
Query: 305 KVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASR 364
+ E+ +T ++L A E F GTA + P+ +I + ++ GP + +
Sbjct: 238 PLLEKSITREELYAA------DEAFFVGTAAEITPIIEIDGR-------VLQRGP-ITQK 283
Query: 365 ILSKLTDIQYGREE 378
I I G+EE
Sbjct: 284 IAETYRRIVLGKEE 297
>6NST-A nrPDB
Length = 307
Score = 267 bits (681), Expect = 8e-72, Method: Composition-based stats.
Identities = 70/323 (21%), Positives = 130/323 (40%), Gaps = 32/323 (9%)
Query: 64 SEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123
W + ++ + H + HY + +FEG++A+ +F+ + DR++ S
Sbjct: 7 DGVIWYDGELVQWRDATTHVLTHTHHYGMGVFEGVRAYDT-PQGTAIFRLQAHTDRLFDS 65
Query: 124 AVRATLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPT-KA 181
A + + + ++E+ E + V+ + S YIRP +G++ K
Sbjct: 66 AHIMNMQIPYSRDEINEATRAAVRENN-------LESAYIRPMVFYGSEGMGLRASGLKV 118
Query: 182 LLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKG-GTGDCKMGGNYGSSLFAQCEAVDN 240
+ + G Y + R K G Y +S+ A EA+
Sbjct: 119 HVIIAAWSWGAYMGEEALQQGIKVRTSSFTRHHVNISMTRAKSNGAYINSMLALQEAISG 178
Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
G + + L E + E N+F+ + + TP + L G+TR IL LA +
Sbjct: 179 GADEAMMLDPE-GYVAEGSGENIFII-----KDGVIYTPEVTA-CLNGITRNTILTLAAE 231
Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
G FK+ E+ +T D++ A E F +GTA V P+ ++ + I GP
Sbjct: 232 HG-FKLVEKRITRDEVYIA------DEAFFTGTAAEVTPIREV----DGRKIGAGRRGP- 279
Query: 361 LASRILSKLTDIQYGREE--SDW 381
+ ++ D+ G+ E ++W
Sbjct: 280 VTEKLQKAYFDLVSGKTEAHAEW 302
>6H65-A nrPDB
Length = 317
Score = 266 bits (680), Expect = 1e-71, Method: Composition-based stats.
Identities = 71/334 (21%), Positives = 140/334 (41%), Gaps = 59/334 (17%)
Query: 65 EFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDN-KIRLFQPNLNMDRMYRS 123
+GW P SLH + A + LFEG++A+ + ++ +F+ + ++ R+ +S
Sbjct: 14 RYGWMNGQCIPWDQCSLHVSTQAAFFGASLFEGVRAYWNAEREQLYVFRLDEHLRRLEQS 73
Query: 124 A----VRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTF-IGTEPSLGVKKP 178
A ++ ++P+ D + + + +L++ ++ + + LY+ F I +P
Sbjct: 74 AKMLRMKLSMPIAD---IRQGVLELLRANE----FRSDVHLYVASYFGINHDPD------ 120
Query: 179 TKALLFVLLSPVGPYFSSGTFN--------PVSLWANPKYVRAWKGGTGDC-----KMGG 225
P+ P +G + P+ + +W+ + D K+G
Sbjct: 121 ----------PLFPTDDTGVYVTGTAVSRLPLVHTGISACMSSWRRISDDSVPPRIKIGA 170
Query: 226 NYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGII 285
NY +S AQ EA NG + L +++E L + + + +PP+ I
Sbjct: 171 NYQNSRLAQTEARVNGYHTSV-LLNSRGKVSETPGACLLMVR-----DGRVISPPVTADI 224
Query: 286 LPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILY 345
L VTR+ ++ L+ + V ER + +L A E+F GT + PV+ I
Sbjct: 225 LESVTRKTLMSLSEAELDSPVIERDMDRTELYIA------EEVFLCGTIAEILPVTTI-- 276
Query: 346 KGETIHIPTMENGPKLASRILSKLTDIQYGREES 379
+ I + E GP + R+ + G+ E+
Sbjct: 277 --DRIQVGDGEVGP-VTRRLQELYFGVTSGQLEA 307
>2EJ2-A nrPDB
Length = 308
Score = 264 bits (674), Expect = 6e-71, Method: Composition-based stats.
Identities = 90/324 (27%), Positives = 130/324 (40%), Gaps = 41/324 (12%)
Query: 63 SSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYR 122
+ W P + S ALHY +FEG++A+ +F+ ++ R Y
Sbjct: 4 KAGLIWMNGAFVPQEEAKTSVLSHALHYGTSVFEGIRAYETAKGP-AIFRLKEHVKRFYN 62
Query: 123 SAVRATLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVK--KPT 179
SA + + F EEL E I+++V+ + S YIRP +LGV
Sbjct: 63 SAKVLRMEIPFAPEELEEAIKEVVRRN-------GYRSCYIRPLAWMGAKALGVNPLPNN 115
Query: 180 KALLFVLLSPVGPYFSS-----GTFNPVSLWAN-PKYVRAWKGGTGDCKMGGNYGSSLFA 233
A + V G Y G S WA P V G K+GGNY +S A
Sbjct: 116 PAEVMVAAWEWGAYLGEEAVRKGARLITSSWARFPANVM-----PGKAKVGGNYVNSALA 170
Query: 234 QCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRC 293
+ EAV G + L L E+ + E NLF DG + + L G+TR
Sbjct: 171 KMEAVAAGADEAL-LLDEEGYVAEGSGENLFFV---RDG---VIYALEHSVNLEGITRDS 223
Query: 294 ILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIP 353
++ +A G ++V T D L A E+F +GTA V PVS I ++ I
Sbjct: 224 VIRIAKDLG-YEVQVVRATRDQLYMA------DEVFMTGTAAEVTPVSMIDWRP----IG 272
Query: 354 TMENGPKLASRILSKLTDIQYGRE 377
GP +A R+ + GR
Sbjct: 273 KGTAGP-VALRLREVYLEAVTGRR 295
>6GKR-A nrPDB
Length = 316
Score = 200 bits (508), Expect = 8e-52, Method: Composition-based stats.
Identities = 62/326 (19%), Positives = 117/326 (35%), Gaps = 34/326 (10%)
Query: 63 SSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRG-VDNKIRLFQPNLNMDRMY 121
+ ++ W I P + ++H +FEG++ + + ++ +F+ + R+
Sbjct: 6 NPKYLWWNHRIIPWEEATVHLTDYWWASVTAVFEGIRGYWNNAEGEMYIFRLEDHARRLE 65
Query: 122 RSAVRATLP-VFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTE-PSLGVKKPT 179
+S +P F +E+ + LV+ + +YI P + V
Sbjct: 66 QSMQLIRMPKEFTVDEICQATIDLVRANDYR------GDVYIMPLAYAVGNKAFSVVGDR 119
Query: 180 KALLFVLLSPVGPYFSSGTFNPV--SLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEA 237
+F+ P S W + K NY +S A EA
Sbjct: 120 TTEMFIYSRPAVSRLEEDFSLHACYSSWTRIN----ERVLPPRIKALANYRNSQLASSEA 175
Query: 238 VDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDL 297
NG L+L E ++ E +F + +L TP + IL +TR ++ L
Sbjct: 176 AMNGYDTALFLNPE-GKVAEGTGSCVFFVR-----KGKLITPDITSGILESITRDTVIHL 229
Query: 298 AHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMEN 357
A + +V ER + + A E F GT + P++ I + +
Sbjct: 230 AREVLGLEVEERVVDRTETYLA------DEAFLCGTHAEITPIASI----DRHEMKHGAP 279
Query: 358 GPKLASRILSKLTDIQYGR--EESDW 381
GP + ++ ++ YGR +W
Sbjct: 280 GP-ITRQLRDIYREVVYGRDFRYRNW 304
>5MQZ-A nrPDB
Length = 290
Score = 180 bits (457), Expect = 7e-46, Method: Composition-based stats.
Identities = 62/314 (19%), Positives = 121/314 (38%), Gaps = 43/314 (13%)
Query: 66 FGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAV 125
+ + P + Y +FEG++A+ G R+F+ ++DR+Y SA
Sbjct: 3 YVYMDGEFVPENEAKVSIFDHGFLYGDGVFEGIRAYNG-----RVFRLKEHIDRLYDSAK 57
Query: 126 RATLPVF-DKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKP--TKAL 182
L + KEE +E I + ++ + YIRP LG+
Sbjct: 58 AIDLEIPITKEEFMEIILETLRKNN-------LRDAYIRPIVTRGIGDLGLDPRKCQNPS 110
Query: 183 LFVLLSPVGPYFS----SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAV 238
+ V+ P G + G + NY +++ A+ EA
Sbjct: 111 IIVITKPWGKLYGDLYEKGLTAITVAVRRNSFDALPPNIKSL-----NYLNNILAKIEAN 165
Query: 239 DNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLA 298
G + ++L + ++E N+F+ + TPP L G+TR ++++
Sbjct: 166 AKGGDEAIFLD-RNGYVSEGSGDNIFVV-----KNGAITTPP-TINNLRGITREAVIEII 218
Query: 299 HQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENG 358
++ G E + + DL TA E+F +GTA + P+ I + I + G
Sbjct: 219 NRLG-IPFKETNIGLYDLYTA------DEVFVTGTAAEIAPIVVI----DGRKIGDGKPG 267
Query: 359 PKLASRILSKLTDI 372
++ +++ + + +
Sbjct: 268 -EITRKLMEEFSKL 280
>5E25-A nrPDB
Length = 291
Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats.
Identities = 62/311 (19%), Positives = 116/311 (37%), Gaps = 43/311 (13%)
Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127
+ P + Y +FEG++A+ G +F+ ++DR+Y A
Sbjct: 6 YMNGEFVPESQAKVSVFDHGFLYGDGVFEGIRAYNGK-----VFKLYEHIDRLYDCARVI 60
Query: 128 TLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKP--TKALLF 184
L + KEE E I + ++ + YIRP LG+ +
Sbjct: 61 DLKIPLSKEEFAEAILETLRRNN-------LRDAYIRPIVTRGAGDLGLDPRKCPSPNVI 113
Query: 185 VLLSPVGPYFS----SGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240
++ P G + G NY +++ A+ EA
Sbjct: 114 IITKPWGKLYGDLYEKGLKAITVAIRRNAIDSLPPNIKSL-----NYLNNILAKIEANAK 168
Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
G + ++L + I+E N+F+ + TPP L G+TR+ +++L ++
Sbjct: 169 GGDEAIFLD-HNGYISEGSGDNIFIV-----KNGTITTPP-TLNNLKGITRQVVIELINE 221
Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
E E + + DL +A E+F +GTA + PV+ I + + + G K
Sbjct: 222 L-EIPFREANIGLFDLYSA------DEIFVTGTAAEIAPVTYI----DGRTVGNGKPG-K 269
Query: 361 LASRILSKLTD 371
+ ++ K +
Sbjct: 270 VTKMLMEKFRE 280
>3CSW-A nrPDB
Length = 285
Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats.
Identities = 68/316 (21%), Positives = 112/316 (35%), Gaps = 51/316 (16%)
Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127
W + + +SL ++E L+ + F + R+ RSA
Sbjct: 16 WWRGKFRRADEISLDFSLFEKSLQGAVYETLRTYSRAP-----FAAYKHYTRLKRSADFF 70
Query: 128 TLP-VFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVL 186
LP +E + ++K + +Y+ P + +
Sbjct: 71 NLPLSLSFDEFTK----VLKAGADEFKQEVRIKVYLFP--------------DSGEVLFV 112
Query: 187 LSPVG-PYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQV 245
SP+ P +G +S + K+ G + A+ E VD C V
Sbjct: 113 FSPLNIPDLETGVEVKISNVRRIPDLSTPP----ALKITGR-TDIVLARREIVD--CYDV 165
Query: 246 LWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFK 305
+ L G + Q+ E N+FL E +L TP LD IL G+TR ++ LA E
Sbjct: 166 I-LLGLNGQVCEGSFSNVFLV-----KEGKLITPSLDSGILDGITRENVIKLAKSL-EIP 218
Query: 306 VSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRI 365
V ER + + +L A EMF + T+ V PV + E GP + + +
Sbjct: 219 VEERVVWVWELFEA------DEMFLTHTSAGVVPVRRLNEHS----FFEEEPGP-VTATL 267
Query: 366 LSKLTDIQYGREESDW 381
+ EE +W
Sbjct: 268 MENFEPFVLNLEE-NW 282
>4JXU-A nrPDB
Length = 295
Score = 107 bits (266), Expect = 9e-24, Method: Composition-based stats.
Identities = 68/308 (22%), Positives = 111/308 (36%), Gaps = 39/308 (12%)
Query: 65 EFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSA 124
+ W + P S A+ +F+G + F G+ +L+ R+ RSA
Sbjct: 18 DGEWLAG-----NPPLIGPTSHAMWLGSTVFDGARWFDGIAPD-----LDLHCQRVNRSA 67
Query: 125 VRATL-PVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALL 183
L P EE+ + VK + ++Y++P + G S V
Sbjct: 68 EALGLKPTMSAEEIEGLAWEGVKK------FDGKTAIYVKPMYWGEHGSWSVVAVDPEST 121
Query: 184 FVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQ 243
L +G SL +P + D K G Y ++ EA G
Sbjct: 122 RFALCLFEAPMGNG-HAGSSLTLSPFRRPTLECMPTDAKAGCLYPNNARILNEARSRGFD 180
Query: 244 QVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGE 303
L I E G+ N+F+ + + TP + L G+TR ++ L + G
Sbjct: 181 NALVRDML-GNIAETGSSNIFMV-----KDGVVFTPAANRTFLAGITRSRVMGLLSEAG- 233
Query: 304 FKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLAS 363
F+V E LTM D A E+F SG V PV+ + + ++ GP + +
Sbjct: 234 FEVIETSLTMADFEGA------DEIFTSGNYSKVLPVTRLEQR-------ELQAGP-VTA 279
Query: 364 RILSKLTD 371
+ D
Sbjct: 280 KARDLYMD 287
>1G2W-A nrPDB
Length = 282
Score = 102 bits (253), Expect = 3e-22, Method: Composition-based stats.
Identities = 54/317 (17%), Positives = 114/317 (35%), Gaps = 64/317 (20%)
Query: 68 WEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRA 127
W I + + + + ++E +K + G +F N ++DR+Y SA +
Sbjct: 5 W-NDQIVKDEEVKIDKEDRGYQFGDGVYEVVKVYNG-----EMFTVNEHIDRLYASAEKI 58
Query: 128 TLPV-FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVL 186
+ + + K++ + + +LV+ ++ +Y +
Sbjct: 59 RITIPYTKDKFHQLLHELVEKNELNT-----GHIY-------------------FQVTRG 94
Query: 187 LSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGG--------------NYGSSLF 232
SP F T PV + + R + K N ++
Sbjct: 95 TSPRAHQFPENTVKPVIIGYTKENPRPLENLEKGVKATFVEDIRWLRCDIKSLNLLGAVL 154
Query: 233 AQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRR 292
A+ EA + GC + + ++ +T + N+F + L T P + +IL G+TR
Sbjct: 155 AKQEAHEKGCYEAI--LHRNNTVTSGSSSNVFGI-----KDGILYTHPANNMILKGITRD 207
Query: 293 CILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHI 352
++ A++ V E T + ++ E+F + T + PV +I K I
Sbjct: 208 VVIACANEI-NMPVKEIPFTTHE------ALKMDELFVTSTTSEITPVIEIDGKL----I 256
Query: 353 PTMENGPKLASRILSKL 369
+ G + ++ +
Sbjct: 257 RDGKVG-EWTRKLQKQF 272
>4PBC-A nrPDB
Length = 316
Score = 89.5 bits (220), Expect = 2e-18, Method: Composition-based stats.
Identities = 47/300 (15%), Positives = 102/300 (34%), Gaps = 25/300 (8%)
Query: 72 HIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPV 131
+ PL + + ++E + + D F+ ++DR+ RS + +
Sbjct: 27 ELVPLSEARVPVLDRGFIFGDGVYEVVPVY-AHDGAHVPFRIEQHLDRLARSLKKIGIDN 85
Query: 132 FDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVG 191
+ + V +A +Y++ T + +F + SP+
Sbjct: 86 PHDAAGWRALIERVVAANAEGLGDGNALVYLQVTRGVAKRGHAFPANAVPTVFAMTSPL- 144
Query: 192 PYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGE 251
S + R W D K G+ L AQ A + + + L E
Sbjct: 145 -RLPSEEERAKGVRCVTAEDRRWLHC--DIKSISLLGNVLMAQ-HAAERDAFETIQLRDE 200
Query: 252 DHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYL 311
+ +TE + N+++ EL PP IL G+ R +++ + R +
Sbjct: 201 N--VTEGSSSNVWIV-----KNGELFAPPRSNKILEGI-RYALVEQLADECGIRFVAREI 252
Query: 312 TMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTD 371
+ +L +A E+ + + PV+ + + + + + GP + + +
Sbjct: 253 SEVELRSA------DEIMLTSATKEILPVTSL----DDLPVQGGKPGP-VFAALYDAYQR 301
>4TM5-A nrPDB
Length = 311
Score = 84.8 bits (208), Expect = 6e-17, Method: Composition-based stats.
Identities = 48/302 (15%), Positives = 103/302 (34%), Gaps = 28/302 (9%)
Query: 72 HIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRL-FQPNLNMDRMYRSAVRATLP 130
+ PL + + ++E + + + R F+ ++ R+ RS + +
Sbjct: 27 ELVPLSEARVPVLDRGFIFGDGVYEVVPIY--AEGARRAPFRIAQHLARLARSLKKIGIA 84
Query: 131 VFDKEELLECIQ-QLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSP 189
E + +LV + + A +YI+ T + +F + SP
Sbjct: 85 DPHDEAGWRALVARLVDANAAALGDGQHAIVYIQVTRGVAKRGHAFPANAVPTVFAMASP 144
Query: 190 VGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLY 249
+ + + R W D K G+ L AQ A ++ + + L
Sbjct: 145 LA--LPTDAQRAQGVHCVTAEDRRWLHC--DIKSVSLLGNVLMAQ-HAAEHDAAETIQL- 198
Query: 250 GEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSER 309
D +TE + N+++ EL PP IL G+ R +++ + + R
Sbjct: 199 -RDGNVTEGSSSNVWIV-----KNGELIAPPRSNRILEGI-RYALVEELAEECGIRFVAR 251
Query: 310 YLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPKLASRILSKL 369
+ +L A E+ + + PV+ + + + + GP + + +
Sbjct: 252 EINEAELRAA------DEILLTSATKEILPVTRL----DDLPVQGGRPGP-VFDALYAAY 300
Query: 370 TD 371
Sbjct: 301 QR 302
>4UUG-A nrPDB
Length = 332
Score = 73.3 bits (178), Expect = 2e-13, Method: Composition-based stats.
Identities = 48/281 (17%), Positives = 93/281 (33%), Gaps = 52/281 (18%)
Query: 109 RLFQPNLNMDRMYRSA--VRATLPVF------------DKEELLECIQQL-VKLDQEWVP 153
R F+ + ++ R+ S +R P+ K + + ++ V V
Sbjct: 67 RFFRLDDHLQRILESCDKMRLKFPLALSSVKNILAEMVAKSGIRDAFVEVIVTRGLTGVR 126
Query: 154 YSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRA 213
S LY ++ P + V P L G ++ R
Sbjct: 127 GSKPEDLYNNNIYLLVLPYIWVMAPENQLH-------------GGEAIITRTVR----RT 169
Query: 214 WKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGE 273
G +G EA+D G +L D +TE N+ L
Sbjct: 170 PPGAFDPTIKNLQWGDLTKGLFEAMDRGA-TYPFLTDGDTNLTEGSGFNIVLV-----KN 223
Query: 274 EELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLTMDDLTTALEGNRVREMFGSGT 333
+ TP D +L G+TR+ ++D+A + + ++ + E+F T
Sbjct: 224 GIIYTP--DRGVLRGITRKSVIDVAR-ANSIDIRLEVVPVEQAYHS------DEIFMCTT 274
Query: 334 ACVVCPVSDILYKGETIHIPTMENGPKLASRILSKLTDIQY 374
A + P++ + + + + GP + +I ++ Y
Sbjct: 275 AGGIMPITLLDGQP----VNDGQVGP-ITKKIWDGYWEMHY 310
>2Y4R-A nrPDB
Length = 292
Score = 71.7 bits (174), Expect = 5e-13, Method: Composition-based stats.
Identities = 58/311 (18%), Positives = 100/311 (32%), Gaps = 46/311 (14%)
Query: 68 WEKPHIKPLQN----LSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRS 123
+ + H+ + L L Y LFE L G ++ R+
Sbjct: 17 YFQGHMLDWVDGRPAAELSVRDRGLAYGDGLFETLAVRAGTPRL-----LERHLARLEEG 71
Query: 124 AVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSL-GVKKPTKA- 181
R +P+ ++Q + + + + L G P +A
Sbjct: 72 CRRLAIPLDTA-----ALRQELLAFCAALGDG------VAKLIVTRGEGLRGYAPPAEAS 120
Query: 182 -LLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN 240
+ SP Y V L+A + G + N + A+ E D
Sbjct: 121 PRRILSGSPRPAYPERHWQQGVRLFACRTRLAEQPLLAGLKHL--NRLEQVLARAEWSDA 178
Query: 241 GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ 300
G + L L ++ E NL L + L P L + GV R +L+ A
Sbjct: 179 GHAEGLMLD-VHERVVEGVFSNLLLVL-----DGTLVAPDLRRCGVAGVMRAELLERAEG 232
Query: 301 WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK 360
G ++ R ++M +L TA E+F + + PV + + P E
Sbjct: 233 IG-VPLAIRDVSMAELATA------DEVFLCNSQFGIWPVRAL----DEHVWPVGE---- 277
Query: 361 LASRILSKLTD 371
L ++ +L D
Sbjct: 278 LTRKLQDQLRD 288
>3SNO-A nrPDB
Length = 315
Score = 55.2 bits (131), Expect = 4e-08, Method: Composition-based stats.
Identities = 57/284 (20%), Positives = 95/284 (33%), Gaps = 36/284 (12%)
Query: 87 ALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVK 146
AL +FE L G + + +R SA LP E+ + Q ++
Sbjct: 42 ALTRGDGIFETLLIRDGHACNV-----RRHGERFKASAALLGLPEPILEDWEKATQMGIE 96
Query: 147 ----------LDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKAL-LFVLLSPVGPYFS 195
W +S + ++ P K + + V+ S G
Sbjct: 97 SWYSHPNAGEASCTWTLSRGRSSTGLASGWLTITPVSSDKLAQREHGVSVMTSSRGYSID 156
Query: 196 SGTFNPVSLWAN--PKYVRA-WKGGTGDCKMGGNYGSSLFAQCEAVDNGCQQVLWLYGED 252
+G K R T K Y +++ A A NG V++ G+
Sbjct: 157 TGLPGIGKATRGELSKVERTPAPWLTVGAKTLA-YAANMAALRYAKSNGFDDVIFTDGDR 215
Query: 253 HQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLT 312
+ E T + + +++ TP G ILPG T+ + A + G ++ E+ L+
Sbjct: 216 --VLEGATSTVVSF-----KGDKIRTPSPGGDILPGTTQAALFAHATEKG-WRCKEKDLS 267
Query: 313 MDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTME 356
+DDL A V + G PV G + P E
Sbjct: 268 IDDLFGADSVWLVSSVRG--------PVRVTRLDGHKLRKPDNE 303
>4K6N-A nrPDB
Length = 383
Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats.
Identities = 25/139 (17%), Positives = 46/139 (33%), Gaps = 16/139 (11%)
Query: 194 FSSGTFNPVSLWANPKYVRAWKGGTGD-CKMGGNYGSSLFAQCEAVDNGCQQVLWLYGED 252
++ F + Y RA + G+ +S +QCE + +
Sbjct: 251 LNASAFTSFKTTSRDHYARARVRMQTAINNLRGSEPTSSVSQCE---------ILFSNKS 301
Query: 253 HQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQWGEFKVSERYLT 312
+ E N+ + + +G ++ TP L L G R +L L + E +
Sbjct: 302 GLLMEGSITNVAVIQKDPNGSKKYVTPRLATGCLCGTMRHYLLRLGL------IEEGDID 355
Query: 313 MDDLTTALEGNRVREMFGS 331
+ LT E + G
Sbjct: 356 IGSLTVGNEVLLFNGVMGC 374
>2V2T-A nrPDB
Length = 288
Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats.
Identities = 9/43 (20%), Positives = 22/43 (51%)
Query: 120 MYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYI 162
++R + PV+DK+ ++ ++++E P + LY+
Sbjct: 169 LHRMDPILSEPVYDKKSTNTSELRICRINKESGPCTGGEELYL 211
>5T49-A nrPDB
Length = 785
Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats.
Identities = 26/165 (15%), Positives = 55/165 (33%), Gaps = 25/165 (15%)
Query: 121 YRSAVRATLPVFDKEELLECIQQLVKLDQEWVP---YSTSASLYIRPTFIGTEPSLGVKK 177
+ SA R F ++ ++ + DQEW + L IR + L
Sbjct: 454 HSSATRINDHHFHYGYFVKAAAEIARADQEWAKSENWGGMIDLLIRDFMADRDDDLFPYL 513
Query: 178 PTKALLFVLLSPVG-PYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCE 236
G F +G + ++ + + AW + GN +
Sbjct: 514 RMFDPYSGNSWADGLATFDAGN----NQESSSEAMHAWTNVILWAEATGN---------K 560
Query: 237 AVDNGCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPL 281
A+ + ++L TE+ +N + + ++++ E P +
Sbjct: 561 ALR---DRAIYL-----YTTEMSAINEYFFDVHQEIFPEEYGPEI 597
>5FXF-A nrPDB
Length = 526
Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats.
Identities = 8/51 (15%), Positives = 19/51 (37%), Gaps = 2/51 (3%)
Query: 26 KAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPL 76
+A++ I+ +L + +G T + L + + F W +
Sbjct: 447 EAREEILQMTKVLVREA--AEAGYGEYRTHNALMDDVMATFNWGDGALLKF 495
>1QNO-A nrPDB
Length = 344
Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 20/60 (33%), Gaps = 5/60 (8%)
Query: 36 TILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALH--YAVE 93
T + +L FG T H+ W + + W I+ L G + Y +
Sbjct: 224 TDFAKNVQIKSLDFG---TFHLYPDSWGTNYTWGNGWIQTHAAACLAAGKPCVFEEYGAQ 280
>6ED1-A nrPDB
Length = 879
Score = 29.8 bits (65), Expect = 2.3, Method: Composition-based stats.
Identities = 14/47 (29%), Positives = 18/47 (38%), Gaps = 2/47 (4%)
Query: 255 ITEVGTMNLFLYWINEDGEEELATPPLDG--IILPGVTRRCILDLAH 299
I EVG NL ++ PP+ G I G+ RR L
Sbjct: 133 ICEVGKENLLAVKVDNSSSLGEILPPVSGDFSIFGGIYRRVFLQWTE 179
>6D8K-A nrPDB
Length = 597
Score = 29.4 bits (64), Expect = 2.9, Method: Composition-based stats.
Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 10/75 (13%)
Query: 53 FTDHMLTVEWSSEFGWEKP----------HIKPLQNLSLHPGSSALHYAVELFEGLKAFR 102
FT + V + GW P + P + L + Y E + +
Sbjct: 462 FTSQLDVVAVNKYMGWYHPWPIEPENAVWEVIPDKPLIISEFGGEALYGQSGDENVASSW 521
Query: 103 GVDNKIRLFQPNLNM 117
+ + RL++ N+ M
Sbjct: 522 SEEYQARLYRDNIRM 536
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.309 0.124 0.322
Lambda K H
0.267 0.0379 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,399,781
Number of Sequences: 36641
Number of extensions: 558010
Number of successful extensions: 1519
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1355
Number of HSP's gapped (non-prelim): 51
length of query: 386
length of database: 10,336,785
effective HSP length: 99
effective length of query: 287
effective length of database: 6,709,326
effective search space: 1925576562
effective search space used: 1925576562
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.3 bits)
S2: 60 (27.8 bits)