BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P54619 (331 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6B2E-C nrPDB 676 0.0 2UV7-A nrPDB 289 1e-78 2OOY-G nrPDB 194 3e-50 3TE5-C nrPDB 191 4e-49 2CU0-A nrPDB 41 9e-04 1VRD-A nrPDB 34 0.069 2YVZ-A nrPDB 32 0.27 2YVX-A nrPDB 31 0.62 4DQW-A nrPDB 30 1.1 3PC3-A nrPDB 30 2.1 1ZFJ-A nrPDB 29 2.7 6A4A-A nrPDB 28 4.5 6GQD-A nrPDB 28 4.6 2CJQ-A nrPDB 28 7.3 >6B2E-C nrPDB Length = 336 Score = 676 bits (1744), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/330 (100%), Positives = 330/330 (100%) Query: 2 ETVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAF 61 ETVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAF Sbjct: 7 ETVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAF 66 Query: 62 FALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY 121 FALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY Sbjct: 67 FALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY 126 Query: 122 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIT 181 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIT Sbjct: 127 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIT 186 Query: 182 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 241 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY Sbjct: 187 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 246 Query: 242 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV 301 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV Sbjct: 247 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV 306 Query: 302 VVDENDVVKGIVSLSDILQALVLTGGEKKP 331 VVDENDVVKGIVSLSDILQALVLTGGEKKP Sbjct: 307 VVDENDVVKGIVSLSDILQALVLTGGEKKP 336 >2UV7-A nrPDB Length = 152 Score = 289 bits (740), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 143/144 (99%), Positives = 143/144 (99%) Query: 182 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 241 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY Sbjct: 9 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 68 Query: 242 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV 301 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVH LV Sbjct: 69 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLV 128 Query: 302 VVDENDVVKGIVSLSDILQALVLT 325 VVDENDVVKGIVSLSDILQALVLT Sbjct: 129 VVDENDVVKGIVSLSDILQALVLT 152 >2OOY-G nrPDB Length = 333 Score = 194 bits (494), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 109/313 (34%), Positives = 186/313 (59%), Gaps = 11/313 (3%) Query: 19 QETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSK 78 QET + +F++S YD++PTS +L+VFD +L VK + L N + +APLWDS+ Sbjct: 4 QETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSE 63 Query: 79 KQSFVGMLTITDFINILHRYYKSALV--QIYELEEHKIETWREVYLQDSFKP--LVCISP 134 F G+LT+ DF+N++ YY+S+ I E+++ ++ REV + P + + P Sbjct: 64 ANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHP 123 Query: 135 NASLFDAVSSLIRNKIHRLPVID--PESGNTLYI--LTHKRILKFLKLFITEFPKPEFMS 190 SL DA ++ +++ R+P+ID E+G+ + + LT RILKF+ + E + Sbjct: 124 MHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKE---TAMLR 180 Query: 191 KSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLA 250 L ++ IGT++N+A T VY + + + +SA+P+V+ +G ++++Y DV++L Sbjct: 181 VPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLI 240 Query: 251 AEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVK 310 + Y+NLD+SV +AL R F+GV C + L+ I + + + VHRL VVDEN ++ Sbjct: 241 QDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLE 300 Query: 311 GIVSLSDILQALV 323 GI+SL+DIL ++ Sbjct: 301 GILSLADILNYII 313 >3TE5-C nrPDB Length = 323 Score = 191 bits (485), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 113/302 (37%), Positives = 175/302 (57%), Gaps = 16/302 (5%) Query: 32 FMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDF 91 F+ S YD++P S +L+V DTSL VKK+ L+ N + +APLWDSK F G+LT TDF Sbjct: 26 FLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSRFAGLLTTTDF 85 Query: 92 INILHRYY----KSALVQIYELEEHK-IETWREVYLQDSFKPLVCISPNASLFDAVSSLI 146 IN++ Y+ K LV +L+ K IE V D+ I P+ LF+A ++ Sbjct: 86 INVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDT----ASIHPSRPLFEACLKML 141 Query: 147 RNKIHRLPVIDPESGN----TLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 202 ++ R+P+ID + + +LT RILKF+ L E F+ + +L I T Sbjct: 142 ESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRE---THFLKIPIGDLNIITQD 198 Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262 N+ + TTPV + + Q RVS++P++DE G ++++Y +DV+ L YN+L +SV Sbjct: 199 NMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKGGIYNDLSLSV 258 Query: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322 +AL RS FEGV C ++ L TI++ + +A VHR VVD+ + G+++LSDIL+ + Sbjct: 259 GEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGVLTLSDILKYI 318 Query: 323 VL 324 +L Sbjct: 319 LL 320 >2CU0-A nrPDB Length = 486 Score = 40.8 bits (94), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 37/149 (24%), Positives = 69/149 (46%), Gaps = 23/149 (15%) Query: 111 EHKIETWREVYLQDSF--KPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILT 168 E ++E + V + + ++ I+P+ ++ A+ + ++ I LPV++ E + I+T Sbjct: 83 EEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEKHGIDGLPVVEDE--KVVGIIT 140 Query: 169 HKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSAL 228 K I + E E ++ V + V AL I +++R+ L Sbjct: 141 KKDIAAREGKLVKELMTKEVIT----------------VPESIEVEEALKIMIENRIDRL 184 Query: 229 PVVDEKGRVVDIYSKFDVINLAAEKTYNN 257 PVVDE+G++V + + D L A K Y N Sbjct: 185 PVVDERGKLVGLITMSD---LVARKKYKN 210 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 53/104 (50%), Gaps = 15/104 (14%) Query: 216 ALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEG 275 AL + +H + LPVV+++ +VV I +K D+ AA + + K L + Sbjct: 115 ALFLMEKHGIDGLPVVEDE-KVVGIITKKDI---AAREG------KLVKELMTKE----- 159 Query: 276 VLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDIL 319 V+ +E + ++E + RL VVDE + G++++SD++ Sbjct: 160 VITVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSDLV 203 >1VRD-A nrPDB Length = 494 Score = 34.3 bits (77), Expect = 0.069, Method: Compositional matrix adjust. Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 13/117 (11%) Query: 209 TTTP---VYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKA 265 T TP V A+ + ++++ LPVVDE+GR+V + + DV + NL + Sbjct: 107 TVTPDMTVKEAIDLMAEYKIGGLPVVDEEGRLVGLLTNRDV------RFEKNLSKKIKDL 160 Query: 266 LQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322 + R L + E + +E +L +V +++ + G++++ DI+ + Sbjct: 161 MTPREKLIVAPPDISLEKAKEILHQHRIE----KLPLVSKDNKLVGLITIKDIMSVI 213 Score = 32.3 bits (72), Expect = 0.31, Method: Compositional matrix adjust. Identities = 28/120 (23%), Positives = 61/120 (50%), Gaps = 13/120 (10%) Query: 130 VCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFM 189 + ++P+ ++ +A+ + KI LPV+D E G + +LT+ R ++F K + Sbjct: 106 ITVTPDMTVKEAIDLMAEYKIGGLPVVD-EEGRLVGLLTN-RDVRFEK----------NL 153 Query: 190 SKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINL 249 SK +++L + + + A I QHR+ LP+V + ++V + + D++++ Sbjct: 154 SKKIKDLMT-PREKLIVAPPDISLEKAKEILHQHRIEKLPLVSKDNKLVGLITIKDIMSV 212 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 35 SHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINI 94 S + DL+ KL+V + ++KA L + + PL SK VG++TI D +++ Sbjct: 154 SKKIKDLMTPREKLIVAPPDISLEKAKEILHQHRIEKLPLV-SKDNKLVGLITIKDIMSV 212 Query: 95 LH 96 + Sbjct: 213 IE 214 >2YVZ-A nrPDB Length = 278 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVIN-LAAEKTYN 256 + VRT T + + + LPVVDE+GR+V I + DV++ L AE T + Sbjct: 208 KVVYVRTDTDQEEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATED 262 >2YVX-A nrPDB Length = 473 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 30/55 (54%), Gaps = 1/55 (1%) Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVIN-LAAEKTYN 256 + VRT T + + + LPVVDE+GR+V I + DV++ L AE T + Sbjct: 228 KVVYVRTDTDQEEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATED 282 >4DQW-A nrPDB Length = 509 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 25/37 (67%) Query: 285 LETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQA 321 LE + +L E + +++VVDEN ++G+V+ DI +A Sbjct: 187 LEEMKAKLYENRIEKMLVVDENFYLRGLVTFRDIEKA 223 >3PC3-A nrPDB Length = 527 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 10/46 (21%), Positives = 31/46 (67%) Query: 128 PLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRIL 173 P V + +A++ +A++ + ++++ +LPV+D + G+ L ++ + ++ Sbjct: 394 PPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLI 439 >1ZFJ-A nrPDB Length = 491 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 24/115 (20%), Positives = 50/115 (43%), Gaps = 12/115 (10%) Query: 132 ISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSK 191 ++P + +A + R +I +P+++ + L + R ++F+ + P E M Sbjct: 103 LTPEHKVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDY--NAPISEHM-- 158 Query: 192 SLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDV 246 T ++ T + A I +HR+ LP+VD GR+ + + D+ Sbjct: 159 --------TSEHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDI 205 >6A4A-A nrPDB Length = 181 Score = 28.5 bits (62), Expect = 4.5, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 255 YNNLDVSVTKALQHR--SHYFEGVLKCYLHETLETIINRLVEAEVHR 299 Y NLDVS K L R E V+K H L+ I + E +V+R Sbjct: 129 YRNLDVSTIKELAKRWKPEVLESVVKTGAHLALDDIKESIAELKVYR 175 >6GQD-A nrPDB Length = 380 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 20/40 (50%) Query: 145 LIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFP 184 L R + RLP + P + L + K + K+ LF T FP Sbjct: 257 LPRRHVRRLPELTPAERDDLASIMKKLLTKYDNLFETSFP 296 >2CJQ-A nrPDB Length = 720 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 5/85 (5%) Query: 97 RYYKSALVQIYELEEHKI-ETWREVYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPV 155 RYY++A I + E+ + + W+ L D KP V P A A++ ++ N + + PV Sbjct: 255 RYYETA---IPKNEKRDVSDDWQSGDLVDEKKPRVIQYPEAKTRLAITKVMYNWVKQQPV 311 Query: 156 IDPE-SGNTLYILTHKRILKFLKLF 179 + P G T ++ K LF Sbjct: 312 VIPGYEGKTPLFNIFNKVRKEWDLF 336 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6B2E-C nrPDB 495 e-140 2OOY-G nrPDB 406 e-114 3TE5-C nrPDB 380 e-106 2UV7-A nrPDB 209 1e-54 2CU0-A nrPDB 134 5e-32 Sequences not found previously or not previously below threshold: 1ZFJ-A nrPDB 66 2e-11 1VRD-A nrPDB 64 7e-11 3TSB-A nrPDB 64 1e-10 4AF0-B nrPDB 60 2e-09 4DQW-A nrPDB 50 2e-06 4Z87-A nrPDB 50 2e-06 3PC3-A nrPDB 46 3e-05 1JCN-A nrPDB 45 5e-05 4HG0-A nrPDB 45 6e-05 4FXS-A nrPDB 44 7e-05 6I0M-A nrPDB 41 7e-04 2YVX-A nrPDB 39 0.004 2YVZ-A nrPDB 37 0.008 1AK5-A nrPDB 34 0.070 4COO-A nrPDB 34 0.087 6A4A-A nrPDB 31 0.62 5K5M-A nrPDB 31 0.81 2GBZ-A nrPDB 30 1.1 1N7G-A nrPDB 30 1.3 5CY4-A nrPDB 29 2.8 5OHX-A nrPDB 28 5.1 1VR9-A nrPDB 28 5.8 2FOM-B nrPDB 27 8.1 >6B2E-C nrPDB Length = 336 Score = 495 bits (1274), Expect = e-140, Method: Composition-based stats. Identities = 330/330 (100%), Positives = 330/330 (100%) Query: 2 ETVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAF 61 ETVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAF Sbjct: 7 ETVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAF 66 Query: 62 FALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY 121 FALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY Sbjct: 67 FALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY 126 Query: 122 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIT 181 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIT Sbjct: 127 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFIT 186 Query: 182 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 241 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY Sbjct: 187 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 246 Query: 242 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV 301 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV Sbjct: 247 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV 306 Query: 302 VVDENDVVKGIVSLSDILQALVLTGGEKKP 331 VVDENDVVKGIVSLSDILQALVLTGGEKKP Sbjct: 307 VVDENDVVKGIVSLSDILQALVLTGGEKKP 336 >2OOY-G nrPDB Length = 333 Score = 406 bits (1042), Expect = e-114, Method: Composition-based stats. Identities = 109/313 (34%), Positives = 186/313 (59%), Gaps = 11/313 (3%) Query: 19 QETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSK 78 QET + +F++S YD++PTS +L+VFD +L VK + L N + +APLWDS+ Sbjct: 4 QETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSE 63 Query: 79 KQSFVGMLTITDFINILHRYYKSALV--QIYELEEHKIETWREVYLQDSFKP--LVCISP 134 F G+LT+ DF+N++ YY+S+ I E+++ ++ REV + P + + P Sbjct: 64 ANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHP 123 Query: 135 NASLFDAVSSLIRNKIHRLPVID--PESGNTL--YILTHKRILKFLKLFITEFPKPEFMS 190 SL DA ++ +++ R+P+ID E+G+ + +LT RILKF+ + E + Sbjct: 124 MHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKE---TAMLR 180 Query: 191 KSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLA 250 L ++ IGT++N+A T VY + + + +SA+P+V+ +G ++++Y DV++L Sbjct: 181 VPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLI 240 Query: 251 AEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVK 310 + Y+NLD+SV +AL R F+GV C + L+ I + + + VHRL VVDEN ++ Sbjct: 241 QDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLE 300 Query: 311 GIVSLSDILQALV 323 GI+SL+DIL ++ Sbjct: 301 GILSLADILNYII 313 >3TE5-C nrPDB Length = 323 Score = 380 bits (975), Expect = e-106, Method: Composition-based stats. Identities = 113/312 (36%), Positives = 176/312 (56%), Gaps = 16/312 (5%) Query: 22 PESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQS 81 + F+ S YD++P S +L+V DTSL VKK+ L+ N + +APLWDSK Sbjct: 16 QQLAVESIRKFLNSKTSYDVLPVSYRLIVLDTSLLVKKSLNVLLQNSIVSAPLWDSKTSR 75 Query: 82 FVGMLTITDFINILHRYY----KSALVQIYELEEHK-IETWREVYLQDSFKPLVCISPNA 136 F G+LT TDFIN++ Y+ K LV +L+ K IE V D+ I P+ Sbjct: 76 FAGLLTTTDFINVIQYYFSNPDKFELVDKLQLDGLKDIERALGVDQLDT----ASIHPSR 131 Query: 137 SLFDAVSSLIRNKIHRLPVIDPESGN----TLYILTHKRILKFLKLFITEFPKPEFMSKS 192 LF+A ++ ++ R+P+ID + + +LT RILKF+ L E F+ Sbjct: 132 PLFEACLKMLESRSGRIPLIDQDEETHREIVVSVLTQYRILKFVALNCRE---THFLKIP 188 Query: 193 LEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAE 252 + +L I T N+ + TTPV + + Q RVS++P++DE G ++++Y +DV+ L Sbjct: 189 IGDLNIITQDNMKSCQMTTPVIDVIQMLTQGRVSSVPIIDENGYLINVYEAYDVLGLIKG 248 Query: 253 KTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGI 312 YN+L +SV +AL RS FEGV C ++ L TI++ + +A VHR VVD+ + G+ Sbjct: 249 GIYNDLSLSVGEALMRRSDDFEGVYTCTKNDKLSTIMDNIRKARVHRFFVVDDVGRLVGV 308 Query: 313 VSLSDILQALVL 324 ++LSDIL+ ++L Sbjct: 309 LTLSDILKYILL 320 >2UV7-A nrPDB Length = 152 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 143/144 (99%), Positives = 143/144 (99%) Query: 182 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 241 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY Sbjct: 9 EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIY 68 Query: 242 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLV 301 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVH LV Sbjct: 69 SKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLV 128 Query: 302 VVDENDVVKGIVSLSDILQALVLT 325 VVDENDVVKGIVSLSDILQALVLT Sbjct: 129 VVDENDVVKGIVSLSDILQALVLT 152 >2CU0-A nrPDB Length = 486 Score = 134 bits (337), Expect = 5e-32, Method: Composition-based stats. Identities = 36/149 (24%), Positives = 68/149 (45%), Gaps = 23/149 (15%) Query: 111 EHKIETWREVYLQDSF--KPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILT 168 E ++E + V + + ++ I+P+ ++ A+ + ++ I LPV++ E + I+T Sbjct: 83 EEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEKHGIDGLPVVEDE--KVVGIIT 140 Query: 169 HKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSAL 228 K I + E E ++ + V AL I +++R+ L Sbjct: 141 KKDIAAREGKLVKELMTKEVITVP----------------ESIEVEEALKIMIENRIDRL 184 Query: 229 PVVDEKGRVVDIYSKFDVINLAAEKTYNN 257 PVVDE+G++V + + D L A K Y N Sbjct: 185 PVVDERGKLVGLITMSD---LVARKKYKN 210 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 31/122 (25%), Positives = 57/122 (46%), Gaps = 16/122 (13%) Query: 198 IGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNN 257 + I + T V AL + +H + LPVV+++ +VV I +K D+ A E Sbjct: 98 LIVEDVITIAPDET-VDFALFLMEKHGIDGLPVVEDE-KVVGIITKKDIA--AREGK--- 150 Query: 258 LDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSD 317 + K L + V+ +E + ++E + RL VVDE + G++++SD Sbjct: 151 ----LVKELMTKE-----VITVPESIEVEEALKIMIENRIDRLPVVDERGKLVGLITMSD 201 Query: 318 IL 319 ++ Sbjct: 202 LV 203 >1ZFJ-A nrPDB Length = 491 Score = 66.3 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 53/311 (17%), Positives = 115/311 (36%), Gaps = 45/311 (14%) Query: 30 TSFMKSHRCYD---LIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGML 86 T F+K +D LIP S ++ + L+ K A + + A + + Sbjct: 5 TKFLKKGYTFDDVLLIPAESHVLPNEVDLKTKLADNLTLNIPIITAAMDTVTGSKMAIAI 64 Query: 87 TITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDS--FKPLVCISPNASLFDAVSS 144 + ++H+ + E R+V ++ ++P + +A Sbjct: 65 ARAGGLGVIHKNMSIT---------EQAEEVRKVKRSENGVIIDPFFLTPEHKVSEAEEL 115 Query: 145 LIRNKIHRLPVIDP-ESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYAN 203 + R +I +P+++ + + I+T++ ++F+ + P E M T + Sbjct: 116 MQRYRISGVPIVETLANRKLVGIITNRD-MRFISDY--NAPISEHM----------TSEH 162 Query: 204 IAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLA-----AEKTYNNL 258 + T + A I +HR+ LP+VD GR+ + + D+ + A+ + L Sbjct: 163 LVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVIEFPHAAKDEFGRL 222 Query: 259 ----DVSVTKALQHRSHYF-----EGVLKCYLHETLETIINRLVEAEVH---RLVVVDEN 306 V VT R+ + ++ H ++ ++ E H R ++ Sbjct: 223 LVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGNI 282 Query: 307 DVVKGIVSLSD 317 +G +L D Sbjct: 283 ATAEGARALYD 293 Score = 40.1 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 54/113 (47%), Gaps = 13/113 (11%) Query: 212 PVYVALGIFVQHRVSALPVVDE--KGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHR 269 V A + ++R+S +P+V+ ++V I + D+ + ++ + +++ + Sbjct: 108 KVSEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFI------SDYNAPISEHMTS- 160 Query: 270 SHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322 E ++ + LET L E + +L +VD + + G++++ DI + + Sbjct: 161 ----EHLVTAAVGTDLETAERILHEHRIEKLPLVDNSGRLSGLITIKDIEKVI 209 >1VRD-A nrPDB Length = 494 Score = 64.4 bits (155), Expect = 7e-11, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 62/144 (43%), Gaps = 22/144 (15%) Query: 115 ETWREVYLQDSFK-----PLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTH 169 E R+V + + + ++P+ ++ +A+ + KI LPV+D E G + +LT+ Sbjct: 86 EQARQVSIVKKTENGIIYDPITVTPDMTVKEAIDLMAEYKIGGLPVVD-EEGRLVGLLTN 144 Query: 170 KRIL--KFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSA 227 + + K L I + P + + + A I QHR+ Sbjct: 145 RDVRFEKNLSKKIKDLMTPR--------------EKLIVAPPDISLEKAKEILHQHRIEK 190 Query: 228 LPVVDEKGRVVDIYSKFDVINLAA 251 LP+V + ++V + + D++++ Sbjct: 191 LPLVSKDNKLVGLITIKDIMSVIE 214 Score = 50.9 bits (120), Expect = 7e-07, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 73/175 (41%), Gaps = 16/175 (9%) Query: 153 LPVIDPESGNTLYILTHKRILK-----FLKLFITEFPKPEFMSKSLEELQIGTYANIAMV 207 +P++ K + + + +T + +S + Y I + Sbjct: 50 IPLVSAAMDTVTEAALAKALAREGGIGIIHKNLTPDEQARQVSIVKKTENGIIYDPITVT 109 Query: 208 RTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQ 267 T V A+ + ++++ LPVVDE+GR+V + + DV + NL + + Sbjct: 110 PDMT-VKEAIDLMAEYKIGGLPVVDEEGRLVGLLTNRDV------RFEKNLSKKIKDLMT 162 Query: 268 HRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322 R E ++ +LE L + + +L +V +++ + G++++ DI+ + Sbjct: 163 PR----EKLIVAPPDISLEKAKEILHQHRIEKLPLVSKDNKLVGLITIKDIMSVI 213 >3TSB-A nrPDB Length = 511 Score = 63.6 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 50/307 (16%), Positives = 113/307 (36%), Gaps = 45/307 (14%) Query: 40 DLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTIT--DFINILHR 97 D++ +K V + VK + + PL GM T+T D + R Sbjct: 39 DVLLVPAKSDVLPREVSVKTVLSESLQLNI---PLIS------AGMDTVTEADMAIAMAR 89 Query: 98 YYKSALVQIYELEEHKIETWREVYLQDS--FKPLVCISPNASLFDAVSSLIRNKIHRLPV 155 ++ E + E +V +S ++P ++DA + + +I +PV Sbjct: 90 QGGLGIIHKNMSIEQQAEQVDKVKRSESGVISDPFFLTPEHQVYDAEHLMGKYRISGVPV 149 Query: 156 IDP-ESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVY 214 ++ + + I+T++ + FI ++ S++ + T + T + Sbjct: 150 VNNLDERKLVGIITNRDM-----RFIQDY--------SIKISDVMTKEQLITAPVGTTLS 196 Query: 215 VALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLA---------AEKTYNNLDVSVTKA 265 A I ++++ LP+VD G + + + D+ + + V VT Sbjct: 197 EAEKILQKYKIEKLPLVDNNGVLQGLITIKDIEKVIEFPNSAKDKQGRLLVGAAVGVTAD 256 Query: 266 LQHR-----SHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQ 320 R + ++ H + +I+++ E +++ G V+ ++ + Sbjct: 257 AMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKEVRAK----YPSLNIIAGNVATAEATK 312 Query: 321 ALVLTGG 327 AL+ G Sbjct: 313 ALIEAGA 319 >4AF0-B nrPDB Length = 556 Score = 59.7 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 38/249 (15%), Positives = 87/249 (34%), Gaps = 35/249 (14%) Query: 10 SPAVENEHPQETPESNNSVYTSFMKSHRC-------YDLIPTSSKLVVFDTSLQVKKAFF 62 +P+ +H +E P + M S + + ++P D SLQ K Sbjct: 29 NPSDALKHLEEYPRGDGLSLQELMDSRKNGGLTYNDFLVLPGHINFPASDVSLQSKATKN 88 Query: 63 ALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYL 122 ++ ++P+ + L + + I+H + E + R V Sbjct: 89 IVLNTPFLSSPMDTVTEDRMAIALALHGGLGIIHHNCSA---------EEQAAMVRRVKK 139 Query: 123 QDS--FKPLVCISPNASLFDAVSSLIRNKIHRLPVID--PESGNTLYILTHKRILKFLKL 178 ++ +C+ P+A++ D + + +P+ + L I+T + + Sbjct: 140 YENGFITDPLCLGPDATVGDVLEIKAKFGFCGVPITETGEPDSKLLGIVTGRDVQFQDA- 198 Query: 179 FITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVV 238 E P M+ + + + A + + + LP+VD G +V Sbjct: 199 ---ETPIKSVMT-----------TEVVTGSSPITLEKANSLLRETKKGKLPIVDSNGHLV 244 Query: 239 DIYSKFDVI 247 + ++ D++ Sbjct: 245 SLVARSDLL 253 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 23/151 (15%), Positives = 54/151 (35%), Gaps = 17/151 (11%) Query: 173 LKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVD 232 L + + + + + + + + T V L I + +P+ + Sbjct: 118 LGIIHHNCSAEEQAAMVRRVKKYENGFITDPLCLGPDAT-VGDVLEIKAKFGFCGVPITE 176 Query: 233 E---KGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETII 289 +++ I + DV + + + + + V+ TLE Sbjct: 177 TGEPDSKLLGIVTGRDV-------QFQDAETPIKSVMTTE------VVTGSSPITLEKAN 223 Query: 290 NRLVEAEVHRLVVVDENDVVKGIVSLSDILQ 320 + L E + +L +VD N + +V+ SD+L+ Sbjct: 224 SLLRETKKGKLPIVDSNGHLVSLVARSDLLK 254 >4DQW-A nrPDB Length = 509 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 73/208 (35%), Gaps = 25/208 (12%) Query: 41 LIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSFVGMLTITDFINILHRYYK 100 LIP S+++ D SL+ + + + +A + + + I I+H+ Sbjct: 36 LIPGYSEVLPKDVSLKTRLTRGIELNIPLVSAAMDTVTEARLAIAMAQEGGIGIIHKNMG 95 Query: 101 SALVQIYELEEHKIETWREVYLQDSFK--PLVCISPNASLFDAVSSLIRNKIHRLPVIDP 158 E + R+V ++ V ++P+ + + + PV++ Sbjct: 96 I---------EQQAAEVRKVKKHETAIVRDPVTVTPSTKIIELLQMAREYGFSGFPVVEQ 146 Query: 159 ESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALG 218 G + I+T + + +K + K + R TP+ Sbjct: 147 --GELVGIVTGRDL--RVKPNAGDTVAAIMTPK----------DKLVTAREGTPLEEMKA 192 Query: 219 IFVQHRVSALPVVDEKGRVVDIYSKFDV 246 ++R+ + VVDE + + + D+ Sbjct: 193 KLYENRIEKMLVVDENFYLRGLVTFRDI 220 >4Z87-A nrPDB Length = 525 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 53/143 (37%), Gaps = 22/143 (15%) Query: 111 EHKIETWREVYLQDS--FKPLVCISPNASLFDAVSSLIRNKIHRLPVIDP--ESGNTLYI 166 E + E R V ++ V + P+A++ D PV D +G I Sbjct: 107 EEQAEMVRRVKKYENGFINAPVVVGPDATVADVRRMKNEFGFAGFPVTDDGKPTGKLQGI 166 Query: 167 LTHKRI--LKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHR 224 +T + I ++ L ++E + ++ + A I + Sbjct: 167 ITSRDIQFVEDETLLVSEIMTKDVITGKQG----------------INLEEANQILKNTK 210 Query: 225 VSALPVVDEKGRVVDIYSKFDVI 247 LP+VDE G +V + S+ D++ Sbjct: 211 KGKLPIVDEAGCLVSMLSRTDLM 233 >3PC3-A nrPDB Length = 527 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 17/137 (12%), Positives = 57/137 (41%), Gaps = 7/137 (5%) Query: 120 VYLQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLF 179 + + P V + +A++ +A++ + ++++ +LPV+D + G+ L ++ + ++ + Sbjct: 386 IAELELPAPPVILKSDATVGEAIALMKKHRVDQLPVVDQDDGSVLGVVGQETLITQIVSM 445 Query: 180 ITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVD 239 + P + + +++ + + V ++ I ++ + + Sbjct: 446 NRQQSDPAIKALNKRVIRLNESEILGKLARVLEVDPSVLILGKNPAGKV-------ELKA 498 Query: 240 IYSKFDVINLAAEKTYN 256 + +K DV A Sbjct: 499 LATKLDVTTFIAAGKQK 515 >1JCN-A nrPDB Length = 514 Score = 44.7 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 59/149 (39%), Gaps = 17/149 (11%) Query: 111 EHKIETWREVYLQDS--FKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPES--GNTLYI 166 E + R+V + V +SP+ ++ D + + +R+ +P+ + + + I Sbjct: 98 EFQANEVRKVKNFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGI 157 Query: 167 LTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVS 226 +T + I FL E M+ +E + + + A I + + Sbjct: 158 VTSRDI-DFLAEKDHTTLLSEVMTPRIE---------LVVAPAGVTLKEANEILQRSKKG 207 Query: 227 ALPVVDEKGRVVDIYSKFDVINLAAEKTY 255 LP+V++ +V I ++ D L + Y Sbjct: 208 KLPIVNDCDELVAIIARTD---LKKNRDY 233 >4HG0-A nrPDB Length = 292 Score = 44.7 bits (104), Expect = 6e-05, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 50/124 (40%), Gaps = 12/124 (9%) Query: 129 LVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEF 188 ++ + N +L + + +I + R PVI + + IL K +L F++ F + Sbjct: 79 MITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKV 138 Query: 189 MSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVIN 248 + +++ +V + V L F R V+DE G V + + D++ Sbjct: 139 LRQAV------------VVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILE 186 Query: 249 LAAE 252 L Sbjct: 187 LIVG 190 Score = 33.5 bits (75), Expect = 0.13, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 53/128 (41%), Gaps = 13/128 (10%) Query: 198 IGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDE-KGRVVDIYSKFDVINLA-AEKTY 255 + + + ++ + L + ++ S PV+ E K + I D++ ++ Sbjct: 73 MIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEA 132 Query: 256 NNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSL 315 ++D + +A+ + ++ ++ H +V+DE V G+V++ Sbjct: 133 FSMDKVLRQAVV-----------VPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTI 181 Query: 316 SDILQALV 323 DIL+ +V Sbjct: 182 EDILELIV 189 >4FXS-A nrPDB Length = 496 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 85/225 (37%), Gaps = 28/225 (12%) Query: 117 WREVYLQDSFKPLVCISPNASLF----DAVSSLIRNKIHRLPVIDPESGNTL-----YIL 167 R +F ++ + ++++ D + L +N +P++ L Sbjct: 4 LRIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMDTVTEARLAIAL 63 Query: 168 THKRILKFLKLFIT-EFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVS 226 + + F+ ++ E + + E + T+ VR + + + H + Sbjct: 64 AQEGGIGFIHKNMSIEQQAAQVHQVKIFEAGVVTHP--VTVRPEQTIADVMELTHYHGFA 121 Query: 227 ALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLE 286 PVV E +V I + DV + +L SV + + E + T Sbjct: 122 GFPVVTENNELVGIITGRDVRFV------TDLTKSVAAVMTPK----ERLATVKEGATGA 171 Query: 287 TIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVLTGGEKKP 331 + ++ +A V +++VV++ +KG+++ D +A E KP Sbjct: 172 EVQEKMHKARVEKILVVNDEFQLKGMITAKDFHKA------ESKP 210 >6I0M-A nrPDB Length = 517 Score = 41.2 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 30/148 (20%), Positives = 56/148 (37%), Gaps = 15/148 (10%) Query: 111 EHKIETWREVYLQDS--FKPLVCISPNASLFDAVSSLIRNKIHRLPVID-PESGNTLYIL 167 E + R+V + V +SP + D + R+ +P+ D G+ L + Sbjct: 101 EFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGI 160 Query: 168 THKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSA 227 R + FLK + E M+K ++ + + A I + + Sbjct: 161 ISSRDIDFLKEEEHDCFLEEIMTK---------REDLVVAPAGITLKEANEILQRSKKGK 211 Query: 228 LPVVDEKGRVVDIYSKFDVINLAAEKTY 255 LP+V+E +V I ++ D L + Y Sbjct: 212 LPIVNEDDELVAIIARTD---LKKNRDY 236 >2YVX-A nrPDB Length = 473 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 157 DPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVA 216 D E+ +Y++ K LK + L + + ++ + + VRT T Sbjct: 187 DAETIYYIYVVDEKGRLKGV-LSLRDL----IVADPRTRVAEIMNPKVVYVRTDTDQEEV 241 Query: 217 LGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNL 258 + + + LPVVDE+GR+V I + DV+++ + ++ Sbjct: 242 ARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDI 283 Score = 31.2 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 18/122 (14%) Query: 206 MVRTTTPVYVALGIFVQHRVSA-----LPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDV 260 VR V L + A + VVDEKGR+ + S D+I A+ ++ Sbjct: 167 AVREGMTVEEVLRFLRRAAPDAETIYYIYVVDEKGRLKGVLSLRDLI--VADPRTRVAEI 224 Query: 261 SVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQ 320 K + R+ + E + + + + L VVDE + GIV++ D+L Sbjct: 225 MNPKVVYVRTDTDQ-----------EEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLD 273 Query: 321 AL 322 L Sbjct: 274 VL 275 >2YVZ-A nrPDB Length = 278 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 46/102 (45%), Gaps = 5/102 (4%) Query: 157 DPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVA 216 D E+ +Y++ K LK + L + + ++ + + VRT T Sbjct: 167 DAETIYYIYVVDEKGRLKGV-LSLRDL----IVADPRTRVAEIMNPKVVYVRTDTDQEEV 221 Query: 217 LGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNL 258 + + + LPVVDE+GR+V I + DV+++ + ++ Sbjct: 222 ARLMADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDI 263 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 18/122 (14%) Query: 206 MVRTTTPVYVALGIFVQHRVSA-----LPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDV 260 VR V L + A + VVDEKGR+ + S D+I A+ ++ Sbjct: 147 AVREGMTVEEVLRFLRRAAPDAETIYYIYVVDEKGRLKGVLSLRDLI--VADPRTRVAEI 204 Query: 261 SVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQ 320 K + R+ + E + + + + L VVDE + GIV++ D+L Sbjct: 205 MNPKVVYVRTDTDQ-----------EEVARLMADYDFTVLPVVDEEGRLVGIVTVDDVLD 253 Query: 321 AL 322 L Sbjct: 254 VL 255 >1AK5-A nrPDB Length = 503 Score = 34.3 bits (77), Expect = 0.070, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 45/108 (41%), Gaps = 13/108 (12%) Query: 132 ISPNASLFDAVSSLIRNKIHRLPVIDPES--GNTLYILTHKRILKFLKLFITEFPKPEFM 189 + P+ + D ++ R + + V D + G L ++T + + L TE + M Sbjct: 110 VKPDQTFADVLAISQRTTHNTVAVTDDGTPHGVLLGLVTQRDYP--IDLTQTETKVSDMM 167 Query: 190 SKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRV 237 + ++ + T + A I + +++ALP++D+ + Sbjct: 168 T---------PFSKLVTAHQDTKLSEANKIIWEKKLNALPIIDDDQHL 206 >4COO-A nrPDB Length = 563 Score = 33.9 bits (76), Expect = 0.087, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 49/108 (45%), Gaps = 11/108 (10%) Query: 217 LGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGV 276 + I + PVVDE G ++ + + ++++ D V K + + F+ + Sbjct: 457 IEILREKGFDQAPVVDEAGVILGMVTLGNMLSSLLAGKVQPSD-QVGKVIYKQ---FKQI 512 Query: 277 LKCYLHETLETIINRLVEAEVHRLVVVDENDV--VKGIVSLSDILQAL 322 L +TL ++ ++E + H +VV E V G+V+ D+L + Sbjct: 513 ---RLTDTL-GRLSHILEMD-HFALVVHEQQRQMVFGVVTAIDLLNFV 555 >6A4A-A nrPDB Length = 181 Score = 31.2 bits (69), Expect = 0.62, Method: Composition-based stats. Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 2/47 (4%) Query: 255 YNNLDVSVTKALQHR--SHYFEGVLKCYLHETLETIINRLVEAEVHR 299 Y NLDVS K L R E V+K H L+ I + E +V+R Sbjct: 129 YRNLDVSTIKELAKRWKPEVLESVVKTGAHLALDDIKESIAELKVYR 175 >5K5M-A nrPDB Length = 635 Score = 30.8 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 28/128 (21%), Positives = 51/128 (39%), Gaps = 7/128 (5%) Query: 190 SKSLEELQIGTYANIAMVRTTTPVYVAL-GIFVQHRVSALPVVDEKGRVVDIYSKFDVIN 248 +LE+L+ M + A+ + Q++V + +G V+DI S+ D Sbjct: 276 RITLEDLKNEEMVTNHMEGEHKKLAEAIFKLTYQNKVVRVQRPTPRGTVMDIISRRDQRG 335 Query: 249 LAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHET------LETIINRLVEAEVHRLVV 302 TY + +A R EGV K H T ++ + R+ + R+ + Sbjct: 336 SGQVGTYGLNTFTNMEAQLIRQMEGEGVFKSIQHLTVTEEIAVQNWLARVGRERLSRMAI 395 Query: 303 VDENDVVK 310 ++ VVK Sbjct: 396 SGDDCVVK 403 >2GBZ-A nrPDB Length = 194 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 20/50 (40%), Gaps = 2/50 (4%) Query: 255 YNNLDVSVTKALQHR--SHYFEGVLKCYLHETLETIINRLVEAEVHRLVV 302 Y NLDVS K L R G K H L + + + E +R + Sbjct: 132 YRNLDVSTIKELARRWAPAVASGFAKSSAHTALSDVRDSIDELRHYRQFM 181 >1N7G-A nrPDB Length = 381 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 24/56 (42%) Query: 86 LTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDA 141 L D++ I RY++ A V + + K + Q F+ LV + + L A Sbjct: 300 LNWKDYVEIDQRYFRPAEVDNLQGDASKAKEVLGWKPQVGFEKLVKMMVDEDLELA 355 >5CY4-A nrPDB Length = 196 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 26/58 (44%), Gaps = 4/58 (6%) Query: 255 YNNLDVSVTKALQH--RSHYFEGVLKCYLHETLETIINRLVEAEVHR--LVVVDENDV 308 Y NLDVS K L R G+ K H ++ I + + E + +R +++ + Sbjct: 138 YRNLDVSTVKELSKRWRPEIMSGLKKNASHLAMDDIRDSISELKYYREYFFIMNTDGK 195 >5OHX-A nrPDB Length = 504 Score = 28.1 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 22/35 (62%) Query: 289 INRLVEAEVHRLVVVDENDVVKGIVSLSDILQALV 323 ++ L A+ LV+ D+N +KG++SL+ + ++ Sbjct: 394 MHMLKNADSQLLVISDDNIHIKGVISLNKLTSYVI 428 >1VR9-A nrPDB Length = 213 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 13/121 (10%) Query: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262 + MV + V L Q++ + V D +G + +K D+++L + + N VS+ Sbjct: 22 DFPMVEESATVRECLHRMRQYQTNECIVKDREGHFRGVVNKEDLLDLDLDSSVFN-KVSL 80 Query: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322 H L +L E + L VVDE +KG VSL D L+AL Sbjct: 81 PDFFVHEEDNITHALLLFL------------EHQEPYLPVVDEEMRLKGAVSLHDFLEAL 128 Query: 323 V 323 + Sbjct: 129 I 129 >2FOM-B nrPDB Length = 185 Score = 27.4 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 26/61 (42%) Query: 181 TEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDI 240 E + + ++ + + +T T A+ + S P+VD+KG+VV + Sbjct: 90 KEGEEVQVLALEPGKNPRAVQTKPGLFKTNTGTIGAVSLDFSPGTSGSPIVDKKGKVVGL 149 Query: 241 Y 241 Y Sbjct: 150 Y 150 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.316 0.130 0.327 Lambda K H 0.267 0.0398 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,991,084 Number of Sequences: 36641 Number of extensions: 391663 Number of successful extensions: 1196 Number of sequences better than 10.0: 32 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1087 Number of HSP's gapped (non-prelim): 76 length of query: 331 length of database: 10,336,785 effective HSP length: 97 effective length of query: 234 effective length of database: 6,782,608 effective search space: 1587130272 effective search space used: 1587130272 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 59 (27.4 bits)