BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P54578 (494 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5GJQ-x nrPDB 1026 0.0 2AYN-A nrPDB 839 0.0 5MPC-8 nrPDB 236 2e-62 1VJV-A nrPDB 198 4e-51 4FIP-A nrPDB 70 3e-12 5L8W-A nrPDB 66 4e-11 5K1A-A nrPDB 65 6e-11 6CPM-C nrPDB 62 6e-10 5L8H-A nrPDB 59 4e-09 3MTN-A nrPDB 57 3e-08 2Y6E-A nrPDB 54 2e-07 5CHV-A nrPDB 53 3e-07 5WCH-A nrPDB 52 4e-07 2GFO-A nrPDB 52 6e-07 6HEH-A nrPDB 52 8e-07 5J7T-A nrPDB 49 5e-06 5JTJ-A nrPDB 48 9e-06 5JTV-A nrPDB 48 1e-05 2F1Z-A nrPDB 47 1e-05 5GVI-A nrPDB 46 4e-05 5O71-A nrPDB 44 1e-04 6H4J-A nrPDB 44 2e-04 6H4H-A nrPDB 43 4e-04 5TXK-A nrPDB 42 6e-04 6DGF-A nrPDB 41 0.001 3IHP-A nrPDB 40 0.003 5OHN-A nrPDB 36 0.032 5OHK-A nrPDB 36 0.038 5FWG-A nrPDB 32 0.47 1IHG-A nrPDB 32 0.52 3SHQ-A nrPDB 32 0.82 5TPR-A nrPDB 30 2.4 1SUJ-A nrPDB 30 2.7 6CN0-A nrPDB 29 4.3 6DCD-A nrPDB 28 7.6 5WTB-D nrPDB 28 9.7 >5GJQ-x nrPDB Length = 494 Score = 1026 bits (2653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 494/494 (100%), Positives = 494/494 (100%) Query: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN Sbjct: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 Query: 61 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV Sbjct: 61 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 Query: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 Query: 181 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 240 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK Sbjct: 181 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 240 Query: 241 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 300 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK Sbjct: 241 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 300 Query: 301 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT 360 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT Sbjct: 301 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT 360 Query: 361 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL 420 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL Sbjct: 361 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL 420 Query: 421 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 480 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY Sbjct: 421 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 480 Query: 481 GPRRVEIMEEESEQ 494 GPRRVEIMEEESEQ Sbjct: 481 GPRRVEIMEEESEQ 494 >2AYN-A nrPDB Length = 404 Score = 839 bits (2167), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/404 (100%), Positives = 404/404 (100%) Query: 91 DMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQ 150 DMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQ Sbjct: 1 DMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQ 60 Query: 151 YITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRV 210 YITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRV Sbjct: 61 YITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRV 120 Query: 211 LQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKE 270 LQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKE Sbjct: 121 LQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKE 180 Query: 271 NQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVR 330 NQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVR Sbjct: 181 NQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVR 240 Query: 331 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD 390 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD Sbjct: 241 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD 300 Query: 391 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKF 450 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKF Sbjct: 301 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKF 360 Query: 451 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ 494 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ Sbjct: 361 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ 404 >5MPC-8 nrPDB Length = 499 Score = 236 bits (602), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 163/503 (32%), Positives = 263/503 (52%), Gaps = 67/503 (13%) Query: 18 VELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKI----KNGMTLLMMG 73 + L+TD K++ LT V ARQK MVKGG ++ +IKI K G T++++G Sbjct: 19 ITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEE---SIKIYPLIKPGSTVMLLG 75 Query: 74 SADA-LPEEPSAKTVFVEDMT-EEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKD 131 + DA L +P+ K F+ED+ E+Q+ +LP G N+GNTCY+NAT+Q + V +L+D Sbjct: 76 TPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRD 135 Query: 132 ALKRYAGALRASGEMAS----AQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQF 186 + Y + S A + I ++ F+++ +K+ S+ PI+LL L +PQF Sbjct: 136 MILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQF 195 Query: 187 AEKGEQGQ-YLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQ 245 AE+ QG Y QQDA E + Q+ + + D E Sbjct: 196 AERDSQGGFYKQQDAEELFTQLF----HSMSIVFGDKFSED------------------- 232 Query: 246 FFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTL 305 F ++F+TT+K T ++ + K E+ +L C I+ ++ GL L E+I K+S Sbjct: 233 -FRIQFKTTIKDTANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLT 291 Query: 306 QRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQE 365 N++Y KISRLP +LT+Q VRFF+K + +K+L+ V FP LD+ ++ TPE Sbjct: 292 GANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAA 351 Query: 366 KMVSFRSKFKDLEDKKVNQQ---------PNTSDKKSSPQKEVKYE-------------- 402 + V R + + +E +K ++ P++S+ +P+++ + + Sbjct: 352 EKVKVRDELRKVEKEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEE 411 Query: 403 ---PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE--WIKFDDDKVSI 457 F + G N Y+L V+THQG +S SGHY ++++ + DE W KF+DDKVS+ Sbjct: 412 YKKHFPPNLEKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSV 471 Query: 458 VTPEDILRLSGGGDWHIAYVLLY 480 V E I L+GGG+ A +L+Y Sbjct: 472 VEKEKIESLAGGGESDSALILMY 494 >1VJV-A nrPDB Length = 415 Score = 198 bits (504), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 131/421 (31%), Positives = 216/421 (51%), Gaps = 58/421 (13%) Query: 94 EEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMAS----A 149 E+Q+ +LP G N+GNTCY+NAT+Q + V +L+D + Y + S A Sbjct: 14 EQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIH 73 Query: 150 QYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQ-YLQQDANECWIQM 207 + I ++ F+++ +K+ S+ P++LL L +PQFAE+ QG Y QQDA E + Q+ Sbjct: 74 KQIVIEMKRCFENLQNKSFKSVLPVVLLNTLRKCYPQFAERDSQGGFYKQQDAEELFTQL 133 Query: 208 MRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTK 267 + + D E F ++F+TT+K T ++ + K Sbjct: 134 F----HSMSIVFGDKFSED--------------------FRIQFKTTIKDTANDNDITVK 169 Query: 268 GKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQ 327 E+ +L C I+ ++ GL L E+I K+S N++Y KISRLP +LT+Q Sbjct: 170 ENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQ 229 Query: 328 MVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQ-- 385 VRFF+K + +K+L+ V FP LD+ ++ TPE + V R + + +E +K ++ Sbjct: 230 YVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKERE 289 Query: 386 -------PNTSDKKSSPQKEVKYE-----------------PFSFADDIGSNNCGYYDLQ 421 P++S+ +P+++ + + F + G N Y+L Sbjct: 290 IKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLI 349 Query: 422 AVLTHQGRSSSSGHYVSWVKRKQDE--WIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLL 479 V+THQG +S SGHY ++++ + DE W KF+DDKVS+V E I L+GGG+ A +L+ Sbjct: 350 GVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILM 409 Query: 480 Y 480 Y Sbjct: 410 Y 410 >4FIP-A nrPDB Length = 476 Score = 69.7 bits (169), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 101/444 (22%), Positives = 184/444 (41%), Gaps = 77/444 (17%) Query: 61 IKIKNGMTLLM-----MGSADALPEEPSAKTVFVEDMTEEQLASAMELP---CGLTNLGN 112 I NG+ +G+ D + + AK + +D+ + + +ME GL N+GN Sbjct: 92 INSNNGLLFCFKCEDYIGNIDLINDAILAK--YWDDVCTKTMVPSMERRDGLSGLINMGN 149 Query: 113 TCYMNATVQCIRSVPE-LKDALKRYAG---ALRASGEMASAQY--ITAALRDLFDSMDKT 166 TC+M++ +QC+ P ++ ++ + +R+ + S I L ++ + Sbjct: 150 TCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQAS 209 Query: 167 SSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKET 226 SSS F+++ + Y QQDA+E W ++ + Q ++ + KE Sbjct: 210 SSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY-VLDLPNAKE- 267 Query: 227 DSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL 286 S A + + ++ F E+++ C + T + L LS I ++ K L Sbjct: 268 ----VSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTT-IDPFLDLSLDI-KDKKKL 321 Query: 287 FTGLKLRLQEEITK----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAK 342 + L ++E K IK I +LP+ L +Q+ RF + S N K Sbjct: 322 YECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGS-NRK 380 Query: 343 VLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYE 402 + ++FP L+M C S + K K E+ KV Sbjct: 381 LDDFIEFPTYLNMKNYC---------STKEKDKHSENGKV-------------------- 411 Query: 403 PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPED 462 DI Y+L +++H+G + + GHY+++ K +W KF+D VS ++ E+ Sbjct: 412 -----PDI------IYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEE 459 Query: 463 ILRLSGGGDWHIAYVLLYGPRRVE 486 +L+ AY+L Y R+V Sbjct: 460 VLKEQ-------AYLLFYTIRQVN 476 >5L8W-A nrPDB Length = 376 Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 87/402 (21%), Positives = 142/402 (35%), Gaps = 96/402 (23%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL N GNTCY N+ +Q + ++ + Y R + + L DLF S+ Sbjct: 46 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTC------LADLFHSIAT 99 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMR----VLQQKLEAI 218 K IPP + L F Y+QQDA+E ++ +LQ++ + Sbjct: 100 QKKKVGVIPPKKFITRLRKENELF------DNYMQQDAHEFLNYLLNTIADILQEERKQE 153 Query: 219 EDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCF 278 + + + + + + + F +C E ++ E+ L LS Sbjct: 154 KQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCET--ISSKDEDFLDLSVD 211 Query: 279 I--NQEVKYLFTGL----------KLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTI 326 + N + + G K +E +KQ K K+ +LP L + Sbjct: 212 VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAH--------KRMKVKKLPMILAL 263 Query: 327 QMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQP 386 + RF Y ++ K+ V FPL L ++ Sbjct: 264 HLKRFKYMDQLHRYTKLSYRVVFPLELRLF------------------------------ 293 Query: 387 NTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE 446 NTS ++P + YDL AV+ H G + GHY++ VK D Sbjct: 294 NTSGDATNPDR-------------------MYDLVAVVVHCGSGPNRGHYIAIVK-SHDF 333 Query: 447 WIKFDDDKVSIVTPEDILRLSG-----GGDWHIAYVLLYGPR 483 W+ FDDD V + + I G + Y+L Y R Sbjct: 334 WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 375 >5K1A-A nrPDB Length = 331 Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 87/402 (21%), Positives = 142/402 (35%), Gaps = 96/402 (23%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL N GNTCY N+ +Q + ++ + Y R + + L DLF S+ Sbjct: 1 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKESLLTC------LADLFHSIAT 54 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMR----VLQQKLEAI 218 K IPP + L F Y+QQDA+E ++ +LQ++ + Sbjct: 55 QKKKVGVIPPKKFITRLRKENELF------DNYMQQDAHEFLNYLLNTIADILQEERKQE 108 Query: 219 EDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCF 278 + + + + + + + F +C E ++ E+ L LS Sbjct: 109 KQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCET--ISSKDEDFLDLSVD 166 Query: 279 I--NQEVKYLFTGL----------KLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTI 326 + N + + G K +E +KQ K K+ +LP L + Sbjct: 167 VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAH--------KRMKVKKLPMILAL 218 Query: 327 QMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQP 386 + RF Y ++ K+ V FPL L ++ Sbjct: 219 HLKRFKYMDQLHRYTKLSYRVVFPLELRLF------------------------------ 248 Query: 387 NTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE 446 NTS ++P + YDL AV+ H G + GHY++ VK D Sbjct: 249 NTSGDATNPDR-------------------MYDLVAVVVHCGSGPNRGHYIAIVK-SHDF 288 Query: 447 WIKFDDDKVSIVTPEDILRLSG-----GGDWHIAYVLLYGPR 483 W+ FDDD V + + I G + Y+L Y R Sbjct: 289 WLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 330 >6CPM-C nrPDB Length = 349 Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 97/399 (24%), Positives = 141/399 (35%), Gaps = 99/399 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDAL--KRYAGALRASGEMASAQYITAALRDLFDS 162 CGL+NLGNTC+MN+ +QC+ + P L + +Y L + I + +L Sbjct: 20 CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQ 79 Query: 163 M--DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIE- 219 M K S P Q A PQF+ Y QQD E ++ L + L I Sbjct: 80 MWSGKFSYVTPRAFKTQVGRFA-PQFS------GYQQQDCQELLAFLLDGLHEDLNRIRK 132 Query: 220 ------DDSVKETDSSSASAATPSKKKS----LIDQFFGVEFETTMKCTESEEEEVTKGK 269 D+ D A A + K ++D F G+ F++T+ C E + VT Sbjct: 133 KPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGL-FKSTLVCPECAKISVTFDP 191 Query: 270 ENQLQLSC------FIN-QEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPA 322 L L F+ ++ LFT K +L E P + + K + LP Sbjct: 192 FCYLTLPLPMPKKPFVKLKDCIELFT-TKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPP 250 Query: 323 YLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKV 382 L + + RF Y R K L D + Sbjct: 251 VLVVHLKRFSYSR---------------------------------YMRDKLDTLVDFPI 277 Query: 383 NQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKR 442 N D+ + C Y+L AV H GHY ++ K Sbjct: 278 N-------------------------DLDMSGCR-YNLIAVSNHY-GGMGGGHYTAFAKN 310 Query: 443 KQD-EWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 480 K D +W FDD VS + + I+ + AYVL Y Sbjct: 311 KDDGKWYYFDDSSVSTASEDQIVSKA-------AYVLFY 342 >5L8H-A nrPDB Length = 359 Score = 59.3 bits (142), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 82/394 (20%), Positives = 135/394 (34%), Gaps = 80/394 (20%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL N GNTCY+N+ +Q + ++ + Y + + + L DLF S+ Sbjct: 29 GLVNFGNTCYVNSVLQALYFCRPFRENVLAY------KAQQKKKENLLTCLADLFHSIAT 82 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDS 222 K IPP + L F Y+QQDA+E ++ + L+ + Sbjct: 83 QKKKVGVIPPKKFISRLRKENDLF------DNYMQQDAHEFLNYLLNTIADILQEEKKQE 136 Query: 223 VKETDSSSASAATPSKKK----SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCF 278 + + + P++ + + + F +C E V+ E+ L LS Sbjct: 137 KQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNC--ETVSSKDEDFLDLSVD 194 Query: 279 INQEVKYLFTGLKLRLQEEITKQ----SPTLQRNALYIKSSKISRLPAYLTIQMVRFFYK 334 + Q E + + T K ++ +LP L + + RF Y Sbjct: 195 VEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYM 254 Query: 335 EKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSS 394 E+ K+ V FPL L ++ NTS + Sbjct: 255 EQLRRYTKLSYRVVFPLELRLF------------------------------NTSSDAVN 284 Query: 395 PQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDK 454 + YDL AV+ H G + GHY++ VK W+ FDDD Sbjct: 285 LDR-------------------MYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLLFDDDI 324 Query: 455 VSIVTPEDILRLSG-----GGDWHIAYVLLYGPR 483 V + + I G + Y+L Y R Sbjct: 325 VEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 358 >3MTN-A nrPDB Length = 373 Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 92/421 (21%), Positives = 144/421 (34%), Gaps = 124/421 (29%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL NLGNTC++NA +QC+ S L+D R G AQ +T A D+ ++ Sbjct: 24 GLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG-GRAQELTEAFADVIGALWH 82 Query: 164 DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSV 223 + ++ P P F+ Y QQDA E +++L ++L + Sbjct: 83 PDSCEAVNPTRFRAVFQKYVPSFS------GYSQQDAQE----FLKLLMERLHLEINRRG 132 Query: 224 KETDSSSASAATPSKKKS------------------------------LIDQFFGVEFET 253 + A+ PS + ++D F G + ++ Sbjct: 133 RRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVG-QLKS 191 Query: 254 TMKCTESEEEEVTKGKENQLQLSCFINQEV-KYLFTGLKLRL---------QEEI-TKQS 302 +KC T ++ C ++ + K F G K+ L +EE+ ++ + Sbjct: 192 CLKCQACGYRSTT------FEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENA 245 Query: 303 PTLQRNALYIKSSK---ISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELC 359 P R +S+K + R P L + + RF + V V FPL Sbjct: 246 PVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSV--GVDFPLQ------- 296 Query: 360 TPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYD 419 R D SDK SP Y Sbjct: 297 -----------RLSLGDF----------ASDKAGSP---------------------VYQ 314 Query: 420 LQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLL 479 L A+ H G S GHY + R Q W ++D +VS V+ + G YVL Sbjct: 315 LYALCNHSG-SVHYGHYTALC-RCQTGWHVYNDSRVSPVSENQVASSEG-------YVLF 365 Query: 480 Y 480 Y Sbjct: 366 Y 366 >2Y6E-A nrPDB Length = 367 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 23/177 (12%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKR--YAGALRASGEMASAQYITAALRDLFDS 162 CGL NLGNTC+MN+ +QC+ + L D + Y + + I A +L Sbjct: 9 CGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQ 68 Query: 163 M--DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIE- 219 M + + P + Q A PQF+ Y QQD+ E ++ L + L ++ Sbjct: 69 MWSGRDAHVAPRMFKTQVGRFA-PQFS------GYQQQDSQELLAFLLDGLHEDLNRVKK 121 Query: 220 ------DDSVKETDSSSASAATPSKK----KSLIDQFFGVEFETTMKCTESEEEEVT 266 D+ D+ A A + + ++D F G+ F++T+ C E + VT Sbjct: 122 KPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGL-FKSTLVCPECAKVSVT 177 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 27/76 (35%), Positives = 38/76 (50%), Gaps = 9/76 (11%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSIVTPEDILRLSGGGDWHIAY 476 YDL AV H G + GHY ++ K K + +W FDD VS+ + + I+ + AY Sbjct: 300 YDLIAVSNHYG-AMGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKA-------AY 351 Query: 477 VLLYGPRRVEIMEEES 492 VL Y R E + S Sbjct: 352 VLFYQRRDDEFYKTPS 367 >5CHV-A nrPDB Length = 323 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 85/386 (22%), Positives = 145/386 (37%), Gaps = 86/386 (22%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-D 164 GL N+G TC +N+ +Q + + LKR A S + L L + M D Sbjct: 8 GLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPF---QLLLLLEKMQD 64 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVK 224 ++ P L+Q L +K ++Q DA + ++ + + + D + Sbjct: 65 SRQKAVLPTELVQCL--------QKYNVPLFVQHDAAQLYLTIWNLTK--------DQIT 108 Query: 225 ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFIN--QE 282 +TD + + F + + ++ C E + K L L F + Sbjct: 109 DTDLTER-----------LQGLFTIWTQESLICVGCTAESSRRSKLLTLSLPLFDKDAKP 157 Query: 283 VKYLFTGLKLRLQEEITKQS----PTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKES 338 +K L L+ +Q + S + + + K++ LP LTI ++RF + S Sbjct: 158 LKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRF--SARNS 215 Query: 339 VNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKE 398 K+ V FP LD ++ E +DL D K Q E Sbjct: 216 RTEKICHSVNFPQSLDFSQVLPTE------------EDLGDTK-------------EQSE 250 Query: 399 VKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSI 457 + YE F AV+ H G + GHY ++++ D +W F+D V Sbjct: 251 IHYELF-----------------AVIAHVGM-ADFGHYCAYIRNPVDGKWFCFNDSHVCW 292 Query: 458 VTPEDILRLSGGGDWH---IAYVLLY 480 VT +D+ G + AY+L+Y Sbjct: 293 VTWKDVQCTYGNHRYRWRETAYLLVY 318 >5WCH-A nrPDB Length = 421 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 98/395 (24%), Positives = 157/395 (39%), Gaps = 78/395 (19%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALR-----ASGEMASAQYITAALRD-- 158 GL N G TCYMN+ +Q + +P +++ + G SG+ RD Sbjct: 9 GLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDDV 68 Query: 159 ------------LFDSMDKTSSSIPPIILLQ--FLHMAFPQFAEKGEQGQYLQQDANECW 204 L + D+ + +I + LQ F H+A + +G + Q W Sbjct: 69 FGYPQQFEDKPALSKTEDRAAYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQ---FRLW 125 Query: 205 IQMMRVLQQKLEAIE--DDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCT---- 258 + + L+++ +A+E + V D + + P+ ++ + G F C Sbjct: 126 GEPVN-LREQHDALEFFNSLVDSLDEALKALGHPA----MLSKVLGGSFADQKICQGCPH 180 Query: 259 --ESEEEEVTKGKE--NQLQLSCFINQEVKY-LFTGLKLRLQEEITKQSPTLQRNALYIK 313 E EE T + N L + Q VK L G E+ K+ T++R L IK Sbjct: 181 RYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTVKR--LLIK 238 Query: 314 SSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSK 373 +LP L IQ+ RF Y + K +FP LDM + V+ +K Sbjct: 239 -----KLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDM--------EPYTVAGVAK 285 Query: 374 FKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSS 433 LE VN P + + S Q E ++ GS Y L VL H G+ +S Sbjct: 286 ---LEGDNVN--PESQLIQQSEQSE--------SETAGSTK---YRLVGVLVHSGQ-ASG 328 Query: 434 GHYVSWVKRK------QDEWIKFDDDKVSIVTPED 462 GHY S++ ++ ++ W KFDD V+ +D Sbjct: 329 GHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDD 363 >2GFO-A nrPDB Length = 396 Score = 52.0 bits (123), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 86/383 (22%), Positives = 137/383 (35%), Gaps = 111/383 (28%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKR--------YAGALRASGEMA---------- 147 GL NLGNTCYMN+ +QC+ + P L D R + L GE+A Sbjct: 64 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKAL 123 Query: 148 -SAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQ 206 + QY + +D ++ K + QFA Y QQD+ E + Sbjct: 124 WTGQYRYISPKDFKITIGKIND----------------QFA------GYSQQDSQELLLF 161 Query: 207 MMRVLQQKLEAI-------EDDSVKETDSSSASAATPSKKK---SLIDQFFGVEFETTMK 256 +M L + L E+++ D +A A K+ S+I F +F++T++ Sbjct: 162 LMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQ 221 Query: 257 CTESEEEEVTKGKENQLQL------SCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNAL 310 C ++ T L L C + ++ KL +R++L Sbjct: 222 CLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSL 281 Query: 311 YIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSF 370 K +I +LP L + + RF Y + K+ V FPL Sbjct: 282 --KKIEIWKLPPVLLVHLKRFSYDGRWK--QKLQTSVDFPL------------------- 318 Query: 371 RSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRS 430 ++L+ + P + KK Y+L +V H G Sbjct: 319 ----ENLDLSQYVIGPKNNLKK-------------------------YNLFSVSNHYG-G 348 Query: 431 SSSGHYVSWVKR-KQDEWIKFDD 452 GHY ++ K + W KFDD Sbjct: 349 LDGGHYTAYCKNAARQRWFKFDD 371 >6HEH-A nrPDB Length = 382 Score = 51.6 bits (122), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 78/393 (19%), Positives = 152/393 (38%), Gaps = 96/393 (24%) Query: 104 PCGLTNLGNTCYMNATVQCIRSVPELKDALKRYA------GALRASGE------MASAQY 151 P GL N+GNTC+ +A +Q + +PE + + Y+ R+ E M QY Sbjct: 14 PVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQY 73 Query: 152 ITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVL 211 + A + M + P L L AF E+ QQD +E +++ L Sbjct: 74 LFALM------MGSNRKFVDPSAALDLLKGAFRSSEEQ-------QQDVSEFTHKLLDWL 120 Query: 212 QQKLEAIEDDSVKETDSSSASAATPSKK--KSLIDQFFGVEFETTMKCTESEEEEVTKGK 269 + + + + +P K ++ F+G ++ + T G+ Sbjct: 121 EDAFQL------------AVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQ 168 Query: 270 ENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMV 329 LQ++ + N + G + E+ +++ Y + ++LP LT ++ Sbjct: 169 Y-PLQVNGYRN--LDECLEGAMVEGDVELLPSDHSVK----YGQERWFTKLPPVLTFELS 221 Query: 330 RFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTS 389 RF + + K+ ++FP ++ M Sbjct: 222 RFEFNQSLGQPEKIHNKLEFPQIIYM---------------------------------- 247 Query: 390 DKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWI 448 + + + GS Y L AVL H+G+ +++GHY +++ + + W+ Sbjct: 248 ------------DRYMYGSGSGSRQVPY-RLHAVLVHEGQ-ANAGHYWAYIYNQPRQSWL 293 Query: 449 KFDDDKVSIVTPEDILRLSGGGDWHI-AYVLLY 480 K++D V+ + E++ R S GG ++ AY L+Y Sbjct: 294 KYNDISVTESSWEEVERDSYGGLRNVSAYCLMY 326 >5J7T-A nrPDB Length = 671 Score = 48.9 bits (115), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 58/177 (32%) Query: 313 KSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRS 372 K K LP L +Q++RF Y + N K+ +FP L + E Sbjct: 181 KGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFL------------- 227 Query: 373 KFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSS 432 +K+ P+ Y L AVL H G + Sbjct: 228 ------------------QKTDPKDPANYI-----------------LHAVLVHSG-DNH 251 Query: 433 SGHYVSWVKRKQD-EWIKFDDDKVSIVTPEDILRLSGGG---DWHI-----AYVLLY 480 GHYV ++ K D +W KFDDD VS T E+ + + GG D + AY+L+Y Sbjct: 252 GGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 308 Score = 29.3 bits (64), Expect = 3.6, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDAL 133 GL N G TCYMN+ +Q + +L+ A+ Sbjct: 5 GLKNQGATCYMNSLLQTLFFTNQLRKAV 32 >5JTJ-A nrPDB Length = 387 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 58/177 (32%) Query: 313 KSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRS 372 K K LP L +Q++RF Y + N K+ +FP L + E Sbjct: 200 KGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFL------------- 246 Query: 373 KFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSS 432 +K+ P+ Y L AVL H G + Sbjct: 247 ------------------QKTDPKDPANYI-----------------LHAVLVHSG-DNH 270 Query: 433 SGHYVSWVKRKQD-EWIKFDDDKVSIVTPEDILRLSGGG---DWHI-----AYVLLY 480 GHYV ++ K D +W KFDDD VS T E+ + + GG D + AY+L+Y Sbjct: 271 GGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 327 Score = 29.6 bits (65), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDAL 133 GL N G TCYMN+ +Q + +L+ A+ Sbjct: 24 GLKNQGATCYMNSLLQTLFFTNQLRKAV 51 >5JTV-A nrPDB Length = 594 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 67/177 (37%), Gaps = 58/177 (32%) Query: 313 KSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRS 372 K K LP L +Q++RF Y + N K+ +FP L + E Sbjct: 200 KGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFL------------- 246 Query: 373 KFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSS 432 +K+ P+ Y L AVL H G + Sbjct: 247 ------------------QKTDPKDPANY-----------------ILHAVLVHSG-DNH 270 Query: 433 SGHYVSWVKRKQD-EWIKFDDDKVSIVTPEDILRLSGGG---DWHI-----AYVLLY 480 GHYV ++ K D +W KFDDD VS T E+ + + GG D + AY+L+Y Sbjct: 271 GGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVY 327 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDAL 133 GL N G TCYMN+ +Q + +L+ A+ Sbjct: 24 GLKNQGATCYMNSLLQTLFFTNQLRKAV 51 >2F1Z-A nrPDB Length = 522 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 42/159 (26%), Positives = 59/159 (37%), Gaps = 50/159 (31%) Query: 313 KSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRS 372 K K LP L +Q++RF Y + N K+ +FP L + E Sbjct: 353 KGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFL------------- 399 Query: 373 KFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSS 432 +K+ P+ Y L AVL H G + Sbjct: 400 ------------------QKTDPKDPANYI-----------------LHAVLVHSG-DNH 423 Query: 433 SGHYVSWVKRKQD-EWIKFDDDKVSIVTPEDILRLSGGG 470 GHYV ++ K D +W KFDDD VS T E+ + + GG Sbjct: 424 GGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGG 462 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDAL 133 GL N G TCYMN+ +Q + +L+ A+ Sbjct: 177 GLKNQGATCYMNSLLQTLFFTNQLRKAV 204 >5GVI-A nrPDB Length = 444 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 101/450 (22%), Positives = 162/450 (36%), Gaps = 86/450 (19%) Query: 99 SAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRD 158 S M + GL NLGNT +MN+ +Q + + P L+ + A E + T R Sbjct: 1 SHMGMVPGLLNLGNTAFMNSLLQGLAACPSFIRWLEDFTSQNSADRERTERE--TQLSRS 58 Query: 159 LFDSMDKTSSSIP-------PIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVL 211 L + SS +P LL+ L + + + +QDA+E + + L Sbjct: 59 LMQLLKALSSHVPGEDDVLDAGGLLEALRLY------RWHISSFEEQDAHELFHVLTSSL 112 Query: 212 Q---------------QKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMK 256 + Q LE + K S P F + M Sbjct: 113 EEEQERQPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHPIPSLWRTRHPFHGRLTSYMA 172 Query: 257 CTESEEEE-VTKGKENQLQLS---------CFINQEVKYLFTG--LKLRLQEEITKQSPT 304 C E++ V + L LS ++Q +++ + +K E TKQ Sbjct: 173 CKRCEQQSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKEVECENCTKQQAG 232 Query: 305 LQRNA--------LYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFP--LMLD 354 N ++K K+ +LP L I + R + KE K + V+F L LD Sbjct: 233 ELVNGEVLESQRTTFVKQLKLGKLPQCLCIHLQRLTWS-KEGSPIKRQEHVQFTEYLSLD 291 Query: 355 MYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD----KKSSPQKEVKYEPFSFADDI 410 Y+ C+ ++ S +K K D K N D + PQ + P F Sbjct: 292 RYKHCSAAQSQQKTSRTNKAKASADPKDKAIANGVDSEHCNNNKPQSNGTF-PSVFLHSP 350 Query: 411 GSN---NCGY--------YDLQAVLTHQGRSSSSGHYVSWVKRK---------QDEWIKF 450 G + N Y + L AVL H G SGH++++ + +W+ Sbjct: 351 GLSSQLNLTYDYSTSEYLFRLTAVLVHHG-DMHSGHFITYRRCPAAPRGTSPFSSQWLWV 409 Query: 451 DDDKVSIVTPEDILRLSGGGDWHIAYVLLY 480 DD V + +++L S AY+L Y Sbjct: 410 SDDSVRKASLQEVLSSS-------AYLLFY 432 >5O71-A nrPDB Length = 716 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 43/65 (66%), Gaps = 3/65 (4%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHI-A 475 Y L AVL H+G+ +++GHY +++ ++ W+K++D V+ + E+++R S GG + A Sbjct: 593 YRLHAVLVHEGQ-ANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASA 651 Query: 476 YVLLY 480 Y L+Y Sbjct: 652 YCLMY 656 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 21/33 (63%) Query: 104 PCGLTNLGNTCYMNATVQCIRSVPELKDALKRY 136 P GL N+GNTC+ +A +Q + ++ E + + Y Sbjct: 170 PVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNY 202 >6H4J-A nrPDB Length = 552 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 43/65 (66%), Gaps = 3/65 (4%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHI-A 475 Y L AVL H+G+ +++GHY +++ ++ W+K++D V+ + E+++R S GG + A Sbjct: 437 YRLHAVLVHEGQ-ANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASA 495 Query: 476 YVLLY 480 Y L+Y Sbjct: 496 YCLMY 500 Score = 34.3 bits (77), Expect = 0.13, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 21/33 (63%) Query: 104 PCGLTNLGNTCYMNATVQCIRSVPELKDALKRY 136 P GL N+GNTC+ +A +Q + ++ E + + Y Sbjct: 14 PVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNY 46 >6H4H-A nrPDB Length = 560 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 42/65 (64%), Gaps = 3/65 (4%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHI-A 475 Y L AVL H G+ +++GHY +++ + + W+K++D V+ + E++ R S GG ++ A Sbjct: 437 YRLHAVLVHDGQ-ANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSA 495 Query: 476 YVLLY 480 Y L+Y Sbjct: 496 YCLMY 500 Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 22/34 (64%) Query: 104 PCGLTNLGNTCYMNATVQCIRSVPELKDALKRYA 137 P GL N+GNTC+ +A +Q + +PE + + Y+ Sbjct: 14 PVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYS 47 >5TXK-A nrPDB Length = 372 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 66/285 (23%), Positives = 115/285 (40%), Gaps = 59/285 (20%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDK 165 GL NLGNT Y+N+ +Q + + + + R ++Q + L+ LF ++ Sbjct: 20 GLINLGNTSYVNSILQALFMASDFRHCVLRLT--------ENNSQPLMTKLQWLFGFLEH 71 Query: 166 TSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDS--- 222 S P I FL ++ + G Q QD +E ++ L +L E Sbjct: 72 --SQRPAISPENFLSASWTPWFSPGTQ-----QDCSE----YLKYLLDRLHEEEKTGTRI 120 Query: 223 ---VKETDSSSASAATPSKKKSLIDQFFGVEFETTMKC-----TESEEEEVT-------- 266 +K++ S S P+ + +++ FG + T + C S EE T Sbjct: 121 CQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPP 180 Query: 267 ---KGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAY 323 +G + L L V Y + KL + +S ++A K ++S+ P Y Sbjct: 181 PGSEGSRSVLDL-------VNYFLSPEKLTAENRYYCESCASLQDA--EKVVELSQGPCY 231 Query: 324 LTIQMVRFFYKEKESVNAKVLKDVKFPLMLDM---------YELC 359 L + ++RF + + K+L DV PL+L + Y+LC Sbjct: 232 LILTLLRFSFDLRTMRRRKILDDVSIPLLLRLPLAGGRGQAYDLC 276 >6DGF-A nrPDB Length = 370 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 15/26 (57%), Positives = 21/26 (80%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKD 131 GL NLGNTC+MN+ +QC+ + EL+D Sbjct: 33 GLRNLGNTCFMNSILQCLSNTRELRD 58 >3IHP-A nrPDB Length = 854 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 56/311 (18%), Positives = 116/311 (37%), Gaps = 81/311 (26%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELK----------------DALKRYAGALRASGE-MAS 148 G+ NLGN+CY+N+ VQ + S+P+ + D + ++ + G + S Sbjct: 346 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 405 Query: 149 AQYITAALR----DLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECW 204 +Y + + I P + + P+F+ QQDA E + Sbjct: 406 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTN------RQQDAQEFF 459 Query: 205 IQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEE 264 + ++ ++++ + E+ ++ F E +KC +E+ + Sbjct: 460 LHLINMVERNCRSSENP----------------------NEVFRFLVEEKIKCLATEKVK 497 Query: 265 VTKGKENQLQLSCFINQEVKYLFTGL-----------KLRLQEEITKQSP---------- 303 T+ + +QL ++ + K+ L E + Q P Sbjct: 498 YTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGA 557 Query: 304 ----------TLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLML 353 LQ ++ +K+++ + P YL IQ+ +F + + V K+ ++ P L Sbjct: 558 PEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFG-LDWVPKKLDVSIEMPEEL 616 Query: 354 DMYELCTPELQ 364 D+ +L LQ Sbjct: 617 DISQLRGTGLQ 627 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 416 GYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKV 455 G Y L A ++H G S+ GHYV +K K+ W+ ++D KV Sbjct: 795 GKYQLFAFISHMGTSTMCGHYVCHIK-KEGRWVIYNDQKV 833 >5OHN-A nrPDB Length = 370 Score = 36.2 bits (82), Expect = 0.032, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGAL-RASGEMASAQY 151 GL NLGNTC+MN+ +Q + + P L+ + R E S QY Sbjct: 8 GLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQY 54 >5OHK-A nrPDB Length = 336 Score = 36.2 bits (82), Expect = 0.038, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGAL-RASGEMASAQY 151 GL NLGNTC+MN+ +Q + + P L+ + R E S QY Sbjct: 8 GLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQY 54 >5FWG-A nrPDB Length = 217 Score = 32.3 bits (72), Expect = 0.47, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 22/36 (61%) Query: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAAL 156 +C+ + P LKD L R+ G + S M S++Y++ + Sbjct: 172 KCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPI 207 >1IHG-A nrPDB Length = 370 Score = 32.3 bits (72), Expect = 0.52, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 24/122 (19%) Query: 36 LTGVQPARQKVMVKGGTLKD-DDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTE 94 + G +PA+ V+ + G LK+ DDWG GS D+ P+ P V ++D+ + Sbjct: 167 VKGEKPAKLCVIAECGELKEGDDWG--------IFPKDGSGDSHPDFPEDADVDLKDVDK 218 Query: 95 EQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALR-ASGEMASAQYIT 153 L S L N+GNT + + + A+K+Y LR G A+A+ Sbjct: 219 ILLISE-----DLKNIGNTFFKSQNWEM---------AIKKYTKVLRYVEGSRAAAEDAD 264 Query: 154 AA 155 A Sbjct: 265 GA 266 >3SHQ-A nrPDB Length = 320 Score = 31.6 bits (70), Expect = 0.82, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 13/76 (17%) Query: 10 WGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVM---VKGGTLKDDDWGNIKI--- 63 W +++ V+L + V + ++F T V+P RQK++ KG T D N+KI Sbjct: 12 WSGKEYP-VDLTDQDTVEVLRHEIFRKTQVRPERQKLLNLKYKGKTAAD----NVKISAL 66 Query: 64 --KNGMTLLMMGSADA 77 K L+M+GS +A Sbjct: 67 ELKPNFKLMMVGSTEA 82 >5TPR-A nrPDB Length = 444 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 28/96 (29%), Positives = 41/96 (42%), Gaps = 12/96 (12%) Query: 15 FEGVELNTDEPPMVFKAQLFALTGVQPARQK-----VMVKGGTLKDDDWGNIKI----KN 65 F G +N D M F A + A G ++ +M + G D +I I Sbjct: 320 FHGHAVNVD---MAFSATIAARRGYITIAERDRILGLMSRVGLSLDHPMLDIDILWRGTE 376 Query: 66 GMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAM 101 +TL G A +P VFV D+T E+LA+A+ Sbjct: 377 SITLTRDGLLRAAMPKPIGDCVFVNDLTREELAAAL 412 >1SUJ-A nrPDB Length = 392 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 16/96 (16%) Query: 248 GVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQR 307 GV+FE C E+ EE++ K N +QL + ++V++ L + + EIT+Q Sbjct: 138 GVDFEVKAFCAENLEEKI--HKRNSVQL---VIRKVQFAPANLGVAPKTEITRQ------ 186 Query: 308 NALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKV 343 ++ S + L A L ++ +++ E +VN K+ Sbjct: 187 ---FMLSDRPLHLEASLDKEI--YYHGEPINVNVKI 217 >6CN0-A nrPDB Length = 284 Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 4/66 (6%) Query: 181 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 240 +FP F E G GQY+ D ++ I+ + + L A E VK+ D S PS + Sbjct: 145 FSFPFFTEAGMLGQYIGFDLDKGMIEAIEHSLRTLNAPEGIVVKQGDILS----DPSGES 200 Query: 241 SLIDQF 246 L+ F Sbjct: 201 DLLLMF 206 >6DCD-A nrPDB Length = 424 Score = 28.5 bits (62), Expect = 7.6, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 12/83 (14%) Query: 107 LTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD-- 164 LT L Y + S PE+ D + R A L A+G+ +A+ +TAA+R L D D Sbjct: 223 LTALATATYPDG------STPEVIDVV-RSATFLFAAGQETTAKLLTAAMRVLGDRPDIQ 275 Query: 165 ---KTSSSIPPIILLQFLHMAFP 184 + + S+ P + + L M P Sbjct: 276 RRLRENRSLIPNFIEESLRMDSP 298 >5WTB-D nrPDB Length = 338 Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 11/65 (16%) Query: 11 GKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQ-----KVMVKGGTLKDDDWGNIKIKN 65 G + + DE + Q++ V P ++ KV + G + DD+GNIK+ N Sbjct: 156 GDSNIQSIFTKLDENKQTIEQQIY----VNPLKKTATNTKVDIAGSQV--DDYGNIKLGN 209 Query: 66 GMTLL 70 G T++ Sbjct: 210 GSTII 214 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5GJQ-x nrPDB 625 e-179 2AYN-A nrPDB 464 e-131 5MPC-8 nrPDB 420 e-118 1VJV-A nrPDB 327 5e-90 4FIP-A nrPDB 322 2e-88 5L8W-A nrPDB 274 5e-74 5K1A-A nrPDB 273 2e-73 5L8H-A nrPDB 271 7e-73 5GVI-A nrPDB 268 4e-72 2Y6E-A nrPDB 265 4e-71 6CPM-C nrPDB 249 2e-66 6HEH-A nrPDB 237 8e-63 5CHV-A nrPDB 237 1e-62 2GFO-A nrPDB 234 6e-62 5WCH-A nrPDB 226 2e-59 3MTN-A nrPDB 225 3e-59 6DGF-A nrPDB 190 1e-48 5TXK-A nrPDB 178 4e-45 5JTJ-A nrPDB 172 2e-43 2F1Z-A nrPDB 172 3e-43 5JTV-A nrPDB 172 3e-43 5J7T-A nrPDB 172 5e-43 6H4H-A nrPDB 170 1e-42 6H4J-A nrPDB 141 7e-34 5O71-A nrPDB 140 1e-33 Sequences not found previously or not previously below threshold: 5OHN-A nrPDB 181 7e-46 5OHK-A nrPDB 170 1e-42 3IHP-A nrPDB 85 6e-17 3JCR-V nrPDB 69 4e-12 3SHQ-A nrPDB 36 0.038 2VHF-A nrPDB 36 0.044 3SEZ-A nrPDB 33 0.22 4MSX-A nrPDB 33 0.41 3G25-A nrPDB 33 0.42 2AKY-A nrPDB 32 0.47 2M8S-A nrPDB 32 0.72 1WXV-A nrPDB 31 0.93 3IHM-A nrPDB 31 1.5 4APL-A nrPDB 30 2.2 4YIV-A nrPDB 30 2.5 1RPA-A nrPDB 29 4.1 6C23-A nrPDB 28 6.7 >5GJQ-x nrPDB Length = 494 Score = 625 bits (1610), Expect = e-179, Method: Composition-based stats. Identities = 494/494 (100%), Positives = 494/494 (100%) Query: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN Sbjct: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 Query: 61 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV Sbjct: 61 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 Query: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 Query: 181 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 240 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK Sbjct: 181 MAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKK 240 Query: 241 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 300 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK Sbjct: 241 SLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK 300 Query: 301 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT 360 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT Sbjct: 301 QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCT 360 Query: 361 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL 420 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL Sbjct: 361 PELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDL 420 Query: 421 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 480 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY Sbjct: 421 QAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLY 480 Query: 481 GPRRVEIMEEESEQ 494 GPRRVEIMEEESEQ Sbjct: 481 GPRRVEIMEEESEQ 494 >2AYN-A nrPDB Length = 404 Score = 464 bits (1192), Expect = e-131, Method: Composition-based stats. Identities = 404/404 (100%), Positives = 404/404 (100%) Query: 91 DMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQ 150 DMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQ Sbjct: 1 DMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQ 60 Query: 151 YITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRV 210 YITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRV Sbjct: 61 YITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRV 120 Query: 211 LQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKE 270 LQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKE Sbjct: 121 LQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKE 180 Query: 271 NQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVR 330 NQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVR Sbjct: 181 NQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVR 240 Query: 331 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD 390 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD Sbjct: 241 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD 300 Query: 391 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKF 450 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKF Sbjct: 301 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKF 360 Query: 451 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ 494 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ Sbjct: 361 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQ 404 >5MPC-8 nrPDB Length = 499 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 162/504 (32%), Positives = 261/504 (51%), Gaps = 67/504 (13%) Query: 18 VELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKI----KNGMTLLMMG 73 + L+TD K++ LT V ARQK MVKGG ++ +IKI K G T++++G Sbjct: 19 ITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEE---SIKIYPLIKPGSTVMLLG 75 Query: 74 SADA-LPEEPSAKTVFVEDMT-EEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKD 131 + DA L +P+ K F+ED+ E+Q+ +LP G N+GNTCY+NAT+Q + V +L+D Sbjct: 76 TPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRD 135 Query: 132 ALKRYAGALRASGEMASAQYI----TAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQF 186 + Y + S A + I ++ F+++ +K+ S+ PI+LL L +PQF Sbjct: 136 MILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQF 195 Query: 187 AEKGEQGQ-YLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQ 245 AE+ QG Y QQDA E + Q+ + + D E Sbjct: 196 AERDSQGGFYKQQDAEELFTQLF----HSMSIVFGDKFSED------------------- 232 Query: 246 FFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTL 305 F ++F+TT+K T ++ + K E+ +L C I+ ++ GL L E+I K+S Sbjct: 233 -FRIQFKTTIKDTANDNDITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLT 291 Query: 306 QRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQE 365 N++Y KISRLP +LT+Q VRFF+K + +K+L+ V FP LD+ ++ TPE Sbjct: 292 GANSIYSVEKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAA 351 Query: 366 KMVSFRSKFK---------DLEDKKVNQQPNTSDKKSSPQKEVKYE-------------- 402 + V R + + + E K+ P++S+ +P+++ + + Sbjct: 352 EKVKVRDELRKVEKEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEE 411 Query: 403 ---PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD--EWIKFDDDKVSI 457 F + G N Y+L V+THQG +S SGHY ++++ + D +W KF+DDKVS+ Sbjct: 412 YKKHFPPNLEKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSV 471 Query: 458 VTPEDILRLSGGGDWHIAYVLLYG 481 V E I L+GGG+ A +L+Y Sbjct: 472 VEKEKIESLAGGGESDSALILMYK 495 >1VJV-A nrPDB Length = 415 Score = 327 bits (838), Expect = 5e-90, Method: Composition-based stats. Identities = 130/422 (30%), Positives = 214/422 (50%), Gaps = 58/422 (13%) Query: 94 EEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYI- 152 E+Q+ +LP G N+GNTCY+NAT+Q + V +L+D + Y + S A + I Sbjct: 14 EQQVQQFAQLPVGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIH 73 Query: 153 ---TAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQ-YLQQDANECWIQM 207 ++ F+++ +K+ S+ P++LL L +PQFAE+ QG Y QQDA E + Q+ Sbjct: 74 KQIVIEMKRCFENLQNKSFKSVLPVVLLNTLRKCYPQFAERDSQGGFYKQQDAEELFTQL 133 Query: 208 MRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTK 267 + + D E F ++F+TT+K T ++ + K Sbjct: 134 F----HSMSIVFGDKFSED--------------------FRIQFKTTIKDTANDNDITVK 169 Query: 268 GKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQ 327 E+ +L C I+ ++ GL L E+I K+S N++Y KISRLP +LT+Q Sbjct: 170 ENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEKKISRLPKFLTVQ 229 Query: 328 MVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFK---------DLE 378 VRFF+K + +K+L+ V FP LD+ ++ TPE + V R + + + E Sbjct: 230 YVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKERE 289 Query: 379 DKKVNQQPNTSDKKSSPQKEVKYE-----------------PFSFADDIGSNNCGYYDLQ 421 K+ P++S+ +P+++ + + F + G N Y+L Sbjct: 290 IKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYNLI 349 Query: 422 AVLTHQGRSSSSGHYVSWVKRKQD--EWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLL 479 V+THQG +S SGHY ++++ + D +W KF+DDKVS+V E I L+GGG+ A +L+ Sbjct: 350 GVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALILM 409 Query: 480 YG 481 Y Sbjct: 410 YK 411 >4FIP-A nrPDB Length = 476 Score = 322 bits (824), Expect = 2e-88, Method: Composition-based stats. Identities = 96/444 (21%), Positives = 177/444 (39%), Gaps = 77/444 (17%) Query: 61 IKIKNGMTLLM-----MGSADALPEEPSAKTVFVEDMTEEQLASAMELP---CGLTNLGN 112 I NG+ +G+ D + + AK + +D+ + + +ME GL N+GN Sbjct: 92 INSNNGLLFCFKCEDYIGNIDLINDAILAK--YWDDVCTKTMVPSMERRDGLSGLINMGN 149 Query: 113 TCYMNATVQCIRSVPEL-KDALKRYAGAL---RASGEMASAQY--ITAALRDLFDSMDKT 166 TC+M++ +QC+ P + ++ + R+ + S I L ++ + Sbjct: 150 TCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQAS 209 Query: 167 SSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKET 226 SSS F+++ + Y QQDA+E W ++ + Q + Sbjct: 210 SSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY------VLDLP 263 Query: 227 DSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL 286 ++ S A + + ++ F E+++ C + T + L LS I ++ K L Sbjct: 264 NAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTT-IDPFLDLSLDI-KDKKKL 321 Query: 287 FTGLKLRLQEEITK----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAK 342 + L ++E K IK I +LP+ L +Q+ RF + N K Sbjct: 322 YECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLN-GSNRK 380 Query: 343 VLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYE 402 + ++FP L+M C S + K K E+ KV Sbjct: 381 LDDFIEFPTYLNMKNYC---------STKEKDKHSENGKV-------------------- 411 Query: 403 PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPED 462 Y+L +++H+G + + GHY+++ K +W KF+D VS ++ E+ Sbjct: 412 -----------PDIIYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEE 459 Query: 463 ILRLSGGGDWHIAYVLLYGPRRVE 486 +L+ AY+L Y R+V Sbjct: 460 VLKEQ-------AYLLFYTIRQVN 476 >5L8W-A nrPDB Length = 376 Score = 274 bits (700), Expect = 5e-74, Method: Composition-based stats. Identities = 84/395 (21%), Positives = 135/395 (34%), Gaps = 80/395 (20%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL N GNTCY N+ +Q + ++ + Y R + L DLF S+ Sbjct: 46 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKES------LLTCLADLFHSIAT 99 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDS 222 K IPP + L F Y+QQDA+E ++ + L+ Sbjct: 100 QKKKVGVIPPKKFITRLRKENELF------DNYMQQDAHEFLNYLLNTIADILQEERKQE 153 Query: 223 VKETDSSSASAAT----PSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCF 278 + + + + + + + F +C E ++ E+ L LS Sbjct: 154 KQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTC--ETISSKDEDFLDLSVD 211 Query: 279 INQE--VKYLFTGLK--LRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYK 334 + Q + + G L E + K K+ +LP L + + RF Y Sbjct: 212 VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYM 271 Query: 335 EKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSS 394 ++ K+ V FPL L ++ NTS ++ Sbjct: 272 DQLHRYTKLSYRVVFPLELRLF------------------------------NTSGDATN 301 Query: 395 PQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDK 454 P + YDL AV+ H G + GHY++ VK D W+ FDDD Sbjct: 302 PDR-------------------MYDLVAVVVHCGSGPNRGHYIAIVK-SHDFWLLFDDDI 341 Query: 455 VSIVTPEDILRLSG-----GGDWHIAYVLLYGPRR 484 V + + I G + Y+L Y R Sbjct: 342 VEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD 376 >5K1A-A nrPDB Length = 331 Score = 273 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 84/395 (21%), Positives = 135/395 (34%), Gaps = 80/395 (20%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL N GNTCY N+ +Q + ++ + Y R + L DLF S+ Sbjct: 1 GLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKES------LLTCLADLFHSIAT 54 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDS 222 K IPP + L F Y+QQDA+E ++ + L+ Sbjct: 55 QKKKVGVIPPKKFITRLRKENELF------DNYMQQDAHEFLNYLLNTIADILQEERKQE 108 Query: 223 VKETDSSSASAAT----PSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCF 278 + + + + + + + F +C E ++ E+ L LS Sbjct: 109 KQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTC--ETISSKDEDFLDLSVD 166 Query: 279 INQE--VKYLFTGLK--LRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYK 334 + Q + + G L E + K K+ +LP L + + RF Y Sbjct: 167 VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYM 226 Query: 335 EKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSS 394 ++ K+ V FPL L ++ NTS ++ Sbjct: 227 DQLHRYTKLSYRVVFPLELRLF------------------------------NTSGDATN 256 Query: 395 PQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDK 454 P + YDL AV+ H G + GHY++ VK D W+ FDDD Sbjct: 257 PDR-------------------MYDLVAVVVHCGSGPNRGHYIAIVK-SHDFWLLFDDDI 296 Query: 455 VSIVTPEDILRLSG-----GGDWHIAYVLLYGPRR 484 V + + I G + Y+L Y R Sbjct: 297 VEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD 331 >5L8H-A nrPDB Length = 359 Score = 271 bits (691), Expect = 7e-73, Method: Composition-based stats. Identities = 82/395 (20%), Positives = 134/395 (33%), Gaps = 80/395 (20%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM-- 163 GL N GNTCY+N+ +Q + ++ + Y + + L DLF S+ Sbjct: 29 GLVNFGNTCYVNSVLQALYFCRPFRENVLAYKAQQ------KKKENLLTCLADLFHSIAT 82 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDS 222 K IPP + L F Y+QQDA+E ++ + L+ + Sbjct: 83 QKKKVGVIPPKKFISRLRKENDLF------DNYMQQDAHEFLNYLLNTIADILQEEKKQE 136 Query: 223 VKETDSSSASAATPS----KKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCF 278 + + + P+ + + + + F +C E V+ E+ L LS Sbjct: 137 KQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNC--ETVSSKDEDFLDLSVD 194 Query: 279 INQEVKYLFTGLKLRLQEEITKQ----SPTLQRNALYIKSSKISRLPAYLTIQMVRFFYK 334 + Q E + + T K ++ +LP L + + RF Y Sbjct: 195 VEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRFKYM 254 Query: 335 EKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSS 394 E+ K+ V FPL L ++ NTS + Sbjct: 255 EQLRRYTKLSYRVVFPLELRLF------------------------------NTSSDAVN 284 Query: 395 PQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDK 454 + YDL AV+ H G + GHY++ VK W+ FDDD Sbjct: 285 LDR-------------------MYDLVAVVVHCGSGPNRGHYITIVK-SHGFWLLFDDDI 324 Query: 455 VSIVTPEDILRLSG-----GGDWHIAYVLLYGPRR 484 V + + I G + Y+L Y R Sbjct: 325 VEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE 359 >5GVI-A nrPDB Length = 444 Score = 268 bits (685), Expect = 4e-72, Method: Composition-based stats. Identities = 98/454 (21%), Positives = 161/454 (35%), Gaps = 86/454 (18%) Query: 99 SAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRD 158 S M + GL NLGNT +MN+ +Q + + P L+ + A E + T R Sbjct: 1 SHMGMVPGLLNLGNTAFMNSLLQGLAACPSFIRWLEDFTSQNSADRERTERE--TQLSRS 58 Query: 159 LFDSMDKTSSSIP-------PIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVL 211 L + SS +P LL+ L + + + +QDA+E + + L Sbjct: 59 LMQLLKALSSHVPGEDDVLDAGGLLEALRLY------RWHISSFEEQDAHELFHVLTSSL 112 Query: 212 QQK---------------LEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMK 256 +++ LE + K S P F + M Sbjct: 113 EEEQERQPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHPIPSLWRTRHPFHGRLTSYMA 172 Query: 257 CTESEEEE-VTKGKENQLQL---------SCFINQEVKYLFTGL--KLRLQEEITKQSPT 304 C E++ V + L L ++Q +++ + K E TKQ Sbjct: 173 CKRCEQQSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKEVECENCTKQQAG 232 Query: 305 LQRN--------ALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFP--LMLD 354 N ++K K+ +LP L I + R + KE K + V+F L LD Sbjct: 233 ELVNGEVLESQRTTFVKQLKLGKLPQCLCIHLQRLTWS-KEGSPIKRQEHVQFTEYLSLD 291 Query: 355 MYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD----KKSSPQKEVKYEPFSFADDI 410 Y+ C+ ++ S +K K D K N D + PQ + P F Sbjct: 292 RYKHCSAAQSQQKTSRTNKAKASADPKDKAIANGVDSEHCNNNKPQSNGTF-PSVFLHSP 350 Query: 411 G-----------SNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRK---------QDEWIKF 450 G S + + L AVL H G SGH++++ + +W+ Sbjct: 351 GLSSQLNLTYDYSTSEYLFRLTAVLVHHG-DMHSGHFITYRRCPAAPRGTSPFSSQWLWV 409 Query: 451 DDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRR 484 DD V + +++L S AY+L Y + Sbjct: 410 SDDSVRKASLQEVLSSS-------AYLLFYERMQ 436 >2Y6E-A nrPDB Length = 367 Score = 265 bits (676), Expect = 4e-71, Method: Composition-based stats. Identities = 93/425 (21%), Positives = 146/425 (34%), Gaps = 103/425 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKR--YAGALRASGEMASAQYITAALRDLFDS 162 CGL NLGNTC+MN+ +QC+ + L D + Y + + I A +L Sbjct: 9 CGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQ 68 Query: 163 M--DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED 220 M + + P + Q A PQF+ Y QQD+ E ++ L + L ++ Sbjct: 69 MWSGRDAHVAPRMFKTQVGRFA-PQFS------GYQQQDSQELLAFLLDGLHEDLNRVKK 121 Query: 221 -------DSVKETDSSSASAATPSKK---KSLIDQFFGVEFETTMKCTESEEEEVTKGKE 270 D+ D+ A A + + S+I F F++T+ C E + VT Sbjct: 122 KPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPF 181 Query: 271 NQLQLSCFINQE-------------------VKYLFTGL--KLRLQEEITKQSPTLQRNA 309 L L + ++ ++ L E P +++ Sbjct: 182 CYLTLPLPLKKDRVMEGPMLQPQKKKKTTVALRDCIELFTTMETLGEHDPWYCPNCKKHQ 241 Query: 310 LYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLM-LDMYELCTPELQEKMV 368 K + LP L + + RF Y K+ V+FP+ L+M E V Sbjct: 242 QATKKFDLWSLPKILVVHLKRFSYNRYW--RDKLDTVVEFPIRGLNMSEFVCNLSARPYV 299 Query: 369 SFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQG 428 YDL AV H G Sbjct: 300 -------------------------------------------------YDLIAVSNHYG 310 Query: 429 RSSSSGHYVSWVKRKQD-EWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEI 487 GHY ++ K K + +W FDD VS+ + + I+ + AYVL Y R E Sbjct: 311 A-MGVGHYTAYAKNKLNGKWYYFDDSNVSLASEDQIVTKA-------AYVLFYQRRDDEF 362 Query: 488 MEEES 492 + S Sbjct: 363 YKTPS 367 >6CPM-C nrPDB Length = 349 Score = 249 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 95/402 (23%), Positives = 138/402 (34%), Gaps = 97/402 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALK--RYAGALRASGEMASAQYITAALRDLFDS 162 CGL+NLGNTC+MN+ +QC+ + P L + +Y L + I + +L Sbjct: 20 CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQ 79 Query: 163 M--DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED 220 M K S P Q A PQF+ Y QQD E ++ L + L I Sbjct: 80 MWSGKFSYVTPRAFKTQVGRFA-PQFS------GYQQQDCQELLAFLLDGLHEDLNRIRK 132 Query: 221 -------DSVKETDSSSASAATPSK---KKSLIDQFFGVEFETTMKCTESEEEEVTKGKE 270 D+ D A A + S+I F F++T+ C E + VT Sbjct: 133 KPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPF 192 Query: 271 NQLQLSCFINQ-------EVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAY 323 L L + + + LFT K +L E P + + K + LP Sbjct: 193 CYLTLPLPMPKKPFVKLKDCIELFT-TKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPV 251 Query: 324 LTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVN 383 L + + RF Y R K L D +N Sbjct: 252 LVVHLKRFSYSR---------------------------------YMRDKLDTLVDFPIN 278 Query: 384 QQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRK 443 D+ + C Y+L AV H G HY ++ K K Sbjct: 279 -------------------------DLDMSGCR-YNLIAVSNHYGGMGGG-HYTAFAKNK 311 Query: 444 QD-EWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRR 484 D +W FDD VS + + I+ + AYVL Y + Sbjct: 312 DDGKWYYFDDSSVSTASEDQIVSKA-------AYVLFYQRQD 346 >6HEH-A nrPDB Length = 382 Score = 237 bits (604), Expect = 8e-63, Method: Composition-based stats. Identities = 75/399 (18%), Positives = 149/399 (37%), Gaps = 80/399 (20%) Query: 102 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQY-----ITAAL 156 P GL N+GNTC+ +A +Q + +PE + + Y+ S L Sbjct: 12 GWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQEL 71 Query: 157 RDLFDS-MDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKL 215 + LF M + P L L AF E QQD +E +++ L+ Sbjct: 72 QYLFALMMGSNRKFVDPSAALDLLKGAFRSSEE-------QQQDVSEFTHKLLDWLEDAF 124 Query: 216 EAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQL 275 + + ++ + ++ F+G ++ + T G+ LQ+ Sbjct: 125 QLAVN----------VNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYP-LQV 173 Query: 276 SCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKE 335 + + N + G + E+ +++ Y + ++LP LT ++ RF + + Sbjct: 174 NGYRN--LDECLEGAMVEGDVELLPSDHSVK----YGQERWFTKLPPVLTFELSRFEFNQ 227 Query: 336 KESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSP 395 K+ ++FP ++ M Sbjct: 228 SLGQPEKIHNKLEFPQIIYM---------------------------------------- 247 Query: 396 QKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDK 454 + + + GS Y L AVL H+G+ +++GHY +++ + + W+K++D Sbjct: 248 ------DRYMYGSGSGSRQVP-YRLHAVLVHEGQ-ANAGHYWAYIYNQPRQSWLKYNDIS 299 Query: 455 VSIVTPEDILRLSGGGDWH-IAYVLLYGPRRVEIMEEES 492 V+ + E++ R S GG + AY L+Y ++ E+ Sbjct: 300 VTESSWEEVERDSYGGLRNVSAYCLMYINDKLPYFNAEA 338 >5CHV-A nrPDB Length = 323 Score = 237 bits (603), Expect = 1e-62, Method: Composition-based stats. Identities = 81/387 (20%), Positives = 138/387 (35%), Gaps = 84/387 (21%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD 164 GL N+G TC +N+ +Q + + LKR A S + L L D Sbjct: 7 VGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPF--QLLLLLEKMQD 64 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVK 224 ++ P L+Q L ++Q DA + ++ + + D + Sbjct: 65 SRQKAVLPTELVQCLQKY--------NVPLFVQHDAAQLYLTIWNLT--------KDQIT 108 Query: 225 ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFIN--QE 282 +TD + + F + + ++ C E + K L L F + Sbjct: 109 DTDLTER-----------LQGLFTIWTQESLICVGCTAESSRRSKLLTLSLPLFDKDAKP 157 Query: 283 VKYLFTGLKLRLQEEITKQ----SPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKES 338 +K L L+ +Q + + + + K++ LP LTI ++RF + S Sbjct: 158 LKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRF--SARNS 215 Query: 339 VNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKE 398 K+ V FP LD ++ E +DL D K Q E Sbjct: 216 RTEKICHSVNFPQSLDFSQVLPTE------------EDLGDTK-------------EQSE 250 Query: 399 VKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSI 457 + Y+L AV+ H G + GHY ++++ D +W F+D V Sbjct: 251 IH-----------------YELFAVIAHVGM-ADFGHYCAYIRNPVDGKWFCFNDSHVCW 292 Query: 458 VTPEDILRLSGGGD---WHIAYVLLYG 481 VT +D+ G AY+L+Y Sbjct: 293 VTWKDVQCTYGNHRYRWRETAYLLVYT 319 >2GFO-A nrPDB Length = 396 Score = 234 bits (596), Expect = 6e-62, Method: Composition-based stats. Identities = 87/397 (21%), Positives = 137/397 (34%), Gaps = 86/397 (21%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKR--YAGALRASGEMASAQYITAALRDLFDSM 163 GL NLGNTCYMN+ +QC+ + P L D R Y + S + + + ++ Sbjct: 64 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKAL 123 Query: 164 DKTSS-SIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAI---- 218 I P + QFA Y QQD+ E + +M L + L Sbjct: 124 WTGQYRYISPKDFKITIGKINDQFA------GYSQQDSQELLLFLMDGLHEDLNKADNRK 177 Query: 219 ---EDDSVKETDSSSASAATPSKKK---SLIDQFFGVEFETTMKCTESEEEEVTKGKENQ 272 E+++ D +A A K+ S+I F +F++T++C ++ T Sbjct: 178 RYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMY 237 Query: 273 LQLS------CFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTI 326 L L C + ++ KL +R++L K +I +LP L + Sbjct: 238 LSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSL--KKIEIWKLPPVLLV 295 Query: 327 QMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQP 386 + RF Y + K+ V FPL +L+ + P Sbjct: 296 HLKRFSYDGRW--KQKLQTSVDFPLE-----------------------NLDLSQYVIGP 330 Query: 387 NTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKR-KQD 445 + KK Y+L +V H G GHY ++ K + Sbjct: 331 KNNLKK-------------------------YNLFSVSNHYG-GLDGGHYTAYCKNAARQ 364 Query: 446 EWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGP 482 W KFDD E AY+L Y Sbjct: 365 RWFKFDD-------HEVSDISVSSVKSSAAYILFYTS 394 >5WCH-A nrPDB Length = 421 Score = 226 bits (574), Expect = 2e-59, Method: Composition-based stats. Identities = 96/441 (21%), Positives = 156/441 (35%), Gaps = 101/441 (22%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALR-----ASGEMASAQYITAALRD- 158 GL N G TCYMN+ +Q + +P +++ + G SG+ RD Sbjct: 8 VGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPRDD 67 Query: 159 -------------LFDSMDKTSSSIPPIILLQ--FLHMAFPQFAEKGEQGQYLQQDANEC 203 L + D+ + +I + LQ F H+A + +G + Q Sbjct: 68 VFGYPQQFEDKPALSKTEDRAAYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQ---FRL 124 Query: 204 WIQMMRVLQQKLEAIE--DDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCT--- 258 W + + L+++ +A+E + V D + + P+ ++ + G F C Sbjct: 125 WGEPVN-LREQHDALEFFNSLVDSLDEALKALGHPA----MLSKVLGGSFADQKICQGCP 179 Query: 259 ---ESEEEEVTKGKE--NQLQLSCFINQEVKY-LFTGLKLRLQEEITKQSPTLQRNALYI 312 E EE T + N L + Q VK L G E+ K+ T+ Sbjct: 180 HRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNKKVDTV------- 232 Query: 313 KSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRS 372 K I +LP L IQ+ RF Y + K +FP LDM + V+ + Sbjct: 233 KRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDM--------EPYTVAGVA 284 Query: 373 KFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSS 432 K + N P + + S Q E + Y L VL H G+ +S Sbjct: 285 KLEG-----DNVNPESQLIQQSEQSESET-----------AGSTKYRLVGVLVHSGQ-AS 327 Query: 433 SGHYVSWVKRK------QDEWIKFDDDKVSIVTPEDILRLSG------------------ 468 GHY S++ ++ ++ W KFDD V+ +D + Sbjct: 328 GGHYYSYIIQRNGGDGERNRWYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKR 387 Query: 469 -----GGDWHIAYVLLYGPRR 484 W AY+L Y Sbjct: 388 MSYRRQKRWWNAYILFYERMD 408 >3MTN-A nrPDB Length = 373 Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats. Identities = 83/426 (19%), Positives = 127/426 (29%), Gaps = 115/426 (26%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM- 163 GL NLGNTC++NA +QC+ S L+D R G AQ +T A D+ ++ Sbjct: 23 VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPG-GGRAQELTEAFADVIGALW 81 Query: 164 -DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDS 222 + ++ P P F+ Y QQDA E +++L ++L + Sbjct: 82 HPDSCEAVNPTRFRAVFQKYVPSFS------GYSQQDAQEF----LKLLMERLHLEINRR 131 Query: 223 VKETDSSSASAATPSKKKS-----------------------------LIDQFFGVEFET 253 + A+ PS + I F + ++ Sbjct: 132 GRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKS 191 Query: 254 TMKCTESEEEEVTKGKENQLQLSCFINQEVKY---LFTGLKLRLQEEITKQ-----SPTL 305 +KC T L L L L +EE + Sbjct: 192 CLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRC 251 Query: 306 QRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQE 365 ++ K + R P L + + RF + V V FPL Sbjct: 252 RQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSV--GVDFPLQ------------- 296 Query: 366 KMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLT 425 R D K Y L A+ Sbjct: 297 -----RLSLGDFASDK-------------------------------AGSPVYQLYALCN 320 Query: 426 HQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRV 485 H G S GHY + + Q W ++D +VS V+ + G YVL Y Sbjct: 321 HSG-SVHYGHYTALCRC-QTGWHVYNDSRVSPVSENQVASSEG-------YVLFYQ---- 367 Query: 486 EIMEEE 491 +M+E Sbjct: 368 -LMQEP 372 >6DGF-A nrPDB Length = 370 Score = 190 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 71/403 (17%), Positives = 126/403 (31%), Gaps = 86/403 (21%) Query: 99 SAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRD 158 + + GL NLGNTC+MN+ +QC+ + EL+D + + + Sbjct: 26 KSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNAHTALVEEFAK 85 Query: 159 LFDSM--DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLE 216 L ++ + + P + P+F Y QQDA E ++ L ++ Sbjct: 86 LIQTIWTSSPNDVVSPSEFKTQIQRYAPRFV------GYNQQDAQEFLRFLLDGLHNEVN 139 Query: 217 AIEDDSVKETDSSSASAATPSKKKSL----------IDQFFGVEFETTMKCTESEEEEVT 266 + ++ ++ I F + ++++ CT+ Sbjct: 140 RVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTV 199 Query: 267 KGKENQLQLSCFINQ-EVKYLFTGLKLRLQEEIT-----KQSPTLQRNALYIKSSKISRL 320 L L L ++L +E++ + IK I R Sbjct: 200 FDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRF 259 Query: 321 PAYLTIQMVRFFYKEKESVNAKVLKDVKFPLM-LDMYELCTPELQEKMVSFRSKFKDLED 379 P L + + RF E +K+ V FPL LD+ E + Sbjct: 260 PKILVLHLKRF--SESRIRTSKLTTFVNFPLRDLDLREFASEN----------------- 300 Query: 380 KKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSW 439 N Y+L AV H G + GHY ++ Sbjct: 301 ---------------------------------TNHAVYNLYAVSNHSGTTM-GGHYTAY 326 Query: 440 VKRKQ-DEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYG 481 + EW F+D V+ ++ + AY+L Y Sbjct: 327 CRSPGTGEWHTFNDSSVTPMSSSQV-------RTSDAYLLFYE 362 >5OHN-A nrPDB Length = 370 Score = 181 bits (458), Expect = 7e-46, Method: Composition-based stats. Identities = 68/430 (15%), Positives = 125/430 (29%), Gaps = 113/430 (26%) Query: 102 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFD 161 L GL NLGNTC+MN+ +Q + + P L+ + + + + Sbjct: 4 GLVPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQYLSLTLLHLL 63 Query: 162 SMDKTSSSI-----PPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQ--- 213 LL L M + + + +QDA+E + + L+ Sbjct: 64 KALSCQEVTDDEVLDASCLLDVLRMY------RWQISSFEEQDAHELFHVITSSLEDERD 117 Query: 214 ------------KLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESE 261 LE + + K+ + + P+ F + M C E Sbjct: 118 RQPRVTHLFDVHSLEQQSEITPKQITCRTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCE 177 Query: 262 EEE-VTKGKENQLQL---------SCFINQEVKYLFTGLKLRLQEEITKQSPTLQ----- 306 + V + L L ++ + + + +R + Sbjct: 178 HQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTLNG 237 Query: 307 -----RNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTP 361 + ++K K+ +LP L I + R + K + V+F LDM E Sbjct: 238 EKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWS-SHGTPLKRHEHVQFNEDLDMDEYKYH 296 Query: 362 ELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQ 421 + L Sbjct: 297 SNASTY-------------------------------------------------LFRLM 307 Query: 422 AVLTHQGRSSSSGHYVSWVKRK---------QDEWIKFDDDKVSIVTPEDILRLSGGGDW 472 AV+ H G SGH+V++ + ++W+ DD V + +++L S Sbjct: 308 AVVVHHG-DMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSS----- 361 Query: 473 HIAYVLLYGP 482 AY+L Y Sbjct: 362 --AYLLFYER 369 >5TXK-A nrPDB Length = 372 Score = 178 bits (451), Expect = 4e-45, Method: Composition-based stats. Identities = 77/398 (19%), Positives = 142/398 (35%), Gaps = 65/398 (16%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD 164 GL NLGNT Y+N+ +Q + + + + R Q + L+ LF ++ Sbjct: 19 IGLINLGNTSYVNSILQALFMASDFRHCVLRLTENNS--------QPLMTKLQWLFGFLE 70 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED--DS 222 S P I FL ++ + G QQD +E ++ L ++ + Sbjct: 71 H--SQRPAISPENFLSASWTPWFSPGT-----QQDCSEYLKYLLDRLHEEEKTGTRICQK 123 Query: 223 VKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQL------- 275 +K++ S S P+ + +++ FG + T + C + L L Sbjct: 124 LKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSREEAFTDLSLAFPPPGS 183 Query: 276 --SCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFY 333 S + V Y + KL + +S ++ K ++S+ P YL + ++RF + Sbjct: 184 EGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQD--AEKVVELSQGPCYLILTLLRFSF 241 Query: 334 KEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKS 393 + K+L DV PL+L + L + S Sbjct: 242 DLRTMRRRKILDDVSIPLLLRL--------------------PLAGGRGQAYDLCSVVVH 281 Query: 394 SPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDD 453 S + +A + + ++S G + +++W F+D Sbjct: 282 SGVSSESGHYYCYAREGAARP---------------AASLG--TADRPEPENQWYLFNDT 324 Query: 454 KVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEE 491 +VS + E + ++ AYVL Y R E E E Sbjct: 325 RVSFSSFESVSNVTSFFPKDTAYVLFYRQRPREGPEAE 362 >5JTJ-A nrPDB Length = 387 Score = 172 bits (436), Expect = 2e-43, Method: Composition-based stats. Identities = 76/388 (19%), Positives = 130/388 (33%), Gaps = 95/388 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD 164 GL N G TCYMN+ +Q + +L+ A+ Y S AL+ +F + Sbjct: 23 VGLKNQGATCYMNSLLQTLFFTNQLRKAV--YMMPTEGDDSSKSVPL---ALQRVFYELQ 77 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVK 224 + + L + ++Q D E ++ ++ K++ Sbjct: 78 HSDKPVGTKKLT--------KSFGWETLDSFMQHDVQELCRVLLDNVENKMK-------- 121 Query: 225 ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVK 284 + I + F + + ++C E + + E+ + I + Sbjct: 122 -GTCVEGT----------IPKLFRGKMVSYIQCKEVDYRSDRR--EDYYDIQLSIKGKKN 168 Query: 285 YLFTGLKLRLQEEI---TKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNA 341 + + E++ K K K LP L +Q++RF Y + N Sbjct: 169 IFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNI 228 Query: 342 KVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKY 401 K+ +FP L + E +K+ P+ Sbjct: 229 KINDRFEFPEQLPLDEFL-------------------------------QKTDPKDPAN- 256 Query: 402 EPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSIVTP 460 Y L AVL H G + GHYV ++ K D +W KFDDD VS T Sbjct: 257 ----------------YILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTK 299 Query: 461 EDILRLSGGGDWH--------IAYVLLY 480 E+ + + GG AY+L+Y Sbjct: 300 EEAIEHNYGGHDDDLSVRHCTNAYMLVY 327 >2F1Z-A nrPDB Length = 522 Score = 172 bits (436), Expect = 3e-43, Method: Composition-based stats. Identities = 76/388 (19%), Positives = 130/388 (33%), Gaps = 95/388 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD 164 GL N G TCYMN+ +Q + +L+ A+ Y S AL+ +F + Sbjct: 176 VGLKNQGATCYMNSLLQTLFFTNQLRKAV--YMMPTEGDDSSKSVPL---ALQRVFYELQ 230 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVK 224 + + L + ++Q D E ++ ++ K++ Sbjct: 231 HSDKPVGTKKLT--------KSFGWETLDSFMQHDVQELCRVLLDNVENKMK-------- 274 Query: 225 ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVK 284 + I + F + + ++C E + + E+ + I + Sbjct: 275 -GTCVEGT----------IPKLFRGKMVSYIQCKEVDYRSDRR--EDYYDIQLSIKGKKN 321 Query: 285 YLFTGLKLRLQEEI---TKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNA 341 + + E++ K K K LP L +Q++RF Y + N Sbjct: 322 IFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNI 381 Query: 342 KVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKY 401 K+ +FP L + E +K+ P+ Sbjct: 382 KINDRFEFPEQLPLDEFL-------------------------------QKTDPKDPAN- 409 Query: 402 EPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSIVTP 460 Y L AVL H G + GHYV ++ K D +W KFDDD VS T Sbjct: 410 ----------------YILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTK 452 Query: 461 EDILRLSGGGDWH--------IAYVLLY 480 E+ + + GG AY+L+Y Sbjct: 453 EEAIEHNYGGHDDDLSVRHCTNAYMLVY 480 >5JTV-A nrPDB Length = 594 Score = 172 bits (435), Expect = 3e-43, Method: Composition-based stats. Identities = 76/388 (19%), Positives = 130/388 (33%), Gaps = 95/388 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD 164 GL N G TCYMN+ +Q + +L+ A+ Y S AL+ +F + Sbjct: 23 VGLKNQGATCYMNSLLQTLFFTNQLRKAV--YMMPTEGDDSSKSVPL---ALQRVFYELQ 77 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVK 224 + + L + ++Q D E ++ ++ K++ Sbjct: 78 HSDKPVGTKKLT--------KSFGWETLDSFMQHDVQELCRVLLDNVENKMK-------- 121 Query: 225 ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVK 284 + I + F + + ++C E + + E+ + I + Sbjct: 122 -GTCVEGT----------IPKLFRGKMVSYIQCKEVDYRSDRR--EDYYDIQLSIKGKKN 168 Query: 285 YLFTGLKLRLQEEI---TKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNA 341 + + E++ K K K LP L +Q++RF Y + N Sbjct: 169 IFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNI 228 Query: 342 KVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKY 401 K+ +FP L + E +K+ P+ Sbjct: 229 KINDRFEFPEQLPLDEFL-------------------------------QKTDPKDPAN- 256 Query: 402 EPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSIVTP 460 Y L AVL H G + GHYV ++ K D +W KFDDD VS T Sbjct: 257 ----------------YILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTK 299 Query: 461 EDILRLSGGGDWH--------IAYVLLY 480 E+ + + GG AY+L+Y Sbjct: 300 EEAIEHNYGGHDDDLSVRHCTNAYMLVY 327 >5J7T-A nrPDB Length = 671 Score = 172 bits (434), Expect = 5e-43, Method: Composition-based stats. Identities = 76/388 (19%), Positives = 130/388 (33%), Gaps = 95/388 (24%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMD 164 GL N G TCYMN+ +Q + +L+ A+ Y S AL+ +F + Sbjct: 4 VGLKNQGATCYMNSLLQTLFFTNQLRKAV--YMMPTEGDDSSKSVPL---ALQRVFYELQ 58 Query: 165 KTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVK 224 + + L + ++Q D E ++ ++ K++ Sbjct: 59 HSDKPVGTKKLT--------KSFGWETLDSFMQHDVQELCRVLLDNVENKMK-------- 102 Query: 225 ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVK 284 + I + F + + ++C E + + E+ + I + Sbjct: 103 -GTCVEGT----------IPKLFRGKMVSYIQCKEVDYRSDRR--EDYYDIQLSIKGKKN 149 Query: 285 YLFTGLKLRLQEEI---TKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNA 341 + + E++ K K K LP L +Q++RF Y + N Sbjct: 150 IFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNI 209 Query: 342 KVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKY 401 K+ +FP L + E +K+ P+ Sbjct: 210 KINDRFEFPEQLPLDEFL-------------------------------QKTDPKDPAN- 237 Query: 402 EPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQD-EWIKFDDDKVSIVTP 460 Y L AVL H G + GHYV ++ K D +W KFDDD VS T Sbjct: 238 ----------------YILHAVLVHSG-DNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTK 280 Query: 461 EDILRLSGGGDWH--------IAYVLLY 480 E+ + + GG AY+L+Y Sbjct: 281 EEAIEHNYGGHDDDLSVRHCTNAYMLVY 308 >5OHK-A nrPDB Length = 336 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 64/415 (15%), Positives = 117/415 (28%), Gaps = 117/415 (28%) Query: 102 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFD 161 L GL NLGNTC+MN+ +Q + + P L+ + + + + Sbjct: 4 GLVPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQYLSLTLLHLL 63 Query: 162 SMDKTSSSI-----PPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLE 216 LL L M + + + +QDA+E + + L+ + + Sbjct: 64 KALSCQEVTDDEVLDASCLLDVLRMY------RWQISSFEEQDAHELFHVITSSLEDERD 117 Query: 217 AIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEE-VTKGKENQLQL 275 S F + M C E + V + L L Sbjct: 118 -------------------GSGSHWKSQHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSL 158 Query: 276 ---------SCFINQEVKYLFTGLKLRLQEEITKQSPTLQ----------RNALYIKSSK 316 ++ + + + +R + + ++K K Sbjct: 159 SIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTLNGEKVEHQRTTFVKQLK 218 Query: 317 ISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKD 376 + +LP L I + R + K + V+F L M E Sbjct: 219 LGKLPQCLCIHLQRLSWS-SHGTPLKRHEHVQFNEDLSMDEYKYHSNASTY--------- 268 Query: 377 LEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHY 436 + L AV+ H G SGH+ Sbjct: 269 ----------------------------------------LFRLMAVVVHHG-DMHSGHF 287 Query: 437 VSWVKRK---------QDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGP 482 V++ + ++W+ DD V + +++L S AY+L Y Sbjct: 288 VTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSS-------AYLLFYER 335 >6H4H-A nrPDB Length = 560 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 54/290 (18%), Positives = 106/290 (36%), Gaps = 30/290 (10%) Query: 102 ELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQY-----ITAAL 156 P GL N+GNTC+ +A +Q + +PE + + Y+ S L Sbjct: 12 GWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQEL 71 Query: 157 RDLFDS-MDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKL 215 + LF M + P L L AF E QQD +E +++ L+ Sbjct: 72 QYLFALMMGSNRKFVDPSAALDLLKGAFRSSEE-------QQQDVSEFTHKLLDWLEDAF 124 Query: 216 EAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQL 275 + + ++ + ++ F+G ++ + T G+ LQ+ Sbjct: 125 QLAVN----------VNSPRNKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYP-LQV 173 Query: 276 SCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKE 335 + + N + G + E+ +++ Y + ++LP LT ++ RF + + Sbjct: 174 NGYRN--LDECLEGAMVEGDVELLPSDHSVK----YGQERWFTKLPPVLTFELSRFEFNQ 227 Query: 336 KESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQ 385 K+ ++FP ++ M + K E+ K+ QQ Sbjct: 228 SLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKLKEEIKILQQ 277 Score = 87.3 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 24/77 (31%), Positives = 45/77 (58%), Gaps = 3/77 (3%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWH-IA 475 Y L AVL H G+ +++GHY +++ + + W+K++D V+ + E++ R S GG + A Sbjct: 437 YRLHAVLVHDGQ-ANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSA 495 Query: 476 YVLLYGPRRVEIMEEES 492 Y L+Y ++ E+ Sbjct: 496 YCLMYINDKLPYFNAEA 512 >6H4J-A nrPDB Length = 552 Score = 141 bits (354), Expect = 7e-34, Method: Composition-based stats. Identities = 50/282 (17%), Positives = 104/282 (36%), Gaps = 31/282 (10%) Query: 104 PCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQY-----ITAALRD 158 P GL N+GNTC+ +A +Q + ++ E + + Y A + + LR Sbjct: 14 PVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRY 73 Query: 159 LFDSM-DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEA 217 LF + + P ++ L F Q QQD +E +++ L+ + Sbjct: 74 LFALLVGTKRKYVDPSRAVEILK---DAFKSNDSQ----QQDVSEFTHKLLDWLEDAFQM 126 Query: 218 IEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSC 277 ++ E K +++ F+G + + E G+ LQ++ Sbjct: 127 KAEEETDE----------EKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYP-LQVNG 175 Query: 278 FINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKE 337 F +++ + + E + + + + LP LT ++ RF + + Sbjct: 176 F--KDLHECLEAAMIEGEIESLHSENSGKS----GQEHWFTELPPVLTFELSRFEFNQAL 229 Query: 338 SVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLED 379 K+ ++FP +L + + + R + K L+D Sbjct: 230 GRPEKIHNKLEFPQVLYLDRYMHRNREITRIK-REEIKRLKD 270 Score = 84.6 bits (207), Expect = 8e-17, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 48/76 (63%), Gaps = 3/76 (3%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWH-IA 475 Y L AVL H+G+ +++GHY +++ ++ W+K++D V+ + E+++R S GG + A Sbjct: 437 YRLHAVLVHEGQ-ANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASA 495 Query: 476 YVLLYGPRRVEIMEEE 491 Y L+Y + + + +E Sbjct: 496 YCLMYINDKAQFLIQE 511 >5O71-A nrPDB Length = 716 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 50/282 (17%), Positives = 104/282 (36%), Gaps = 31/282 (10%) Query: 104 PCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQY-----ITAALRD 158 P GL N+GNTC+ +A +Q + ++ E + + Y A + + LR Sbjct: 170 PVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRY 229 Query: 159 LFDSM-DKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEA 217 LF + + P ++ L F Q QQD +E +++ L+ + Sbjct: 230 LFALLVGTKRKYVDPSRAVEILK---DAFKSNDSQ----QQDVSEFTHKLLDWLEDAFQM 282 Query: 218 IEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSC 277 ++ E K +++ F+G + + E G+ LQ++ Sbjct: 283 KAEEETDE----------EKPKNPMVELFYGRFLAVGVLEGKKFENTEMFGQYP-LQVNG 331 Query: 278 FINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKE 337 F +++ + + E + + + + LP LT ++ RF + + Sbjct: 332 F--KDLHECLEAAMIEGEIESLHSENSGKS----GQEHWFTELPPVLTFELSRFEFNQAL 385 Query: 338 SVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLED 379 K+ ++FP +L + + + R + K L+D Sbjct: 386 GRPEKIHNKLEFPQVLYLDRYMHRNREITRIK-REEIKRLKD 426 Score = 84.6 bits (207), Expect = 9e-17, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 48/76 (63%), Gaps = 3/76 (3%) Query: 418 YDLQAVLTHQGRSSSSGHYVSWV-KRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWH-IA 475 Y L AVL H+G+ +++GHY +++ ++ W+K++D V+ + E+++R S GG + A Sbjct: 593 YRLHAVLVHEGQ-ANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSFGGYRNASA 651 Query: 476 YVLLYGPRRVEIMEEE 491 Y L+Y + + + +E Sbjct: 652 YCLMYINDKAQFLIQE 667 >3IHP-A nrPDB Length = 854 Score = 85.4 bits (209), Expect = 6e-17, Method: Composition-based stats. Identities = 55/333 (16%), Positives = 112/333 (33%), Gaps = 81/333 (24%) Query: 106 GLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDK 165 G+ NLGN+CY+N+ VQ + S+P+ + + + Q + + L + Sbjct: 346 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 405 Query: 166 TSSSIP---------------------PIILLQFLHMAFPQFAEKGEQGQYLQQDANECW 204 S P P + + P+F+ QQDA E + Sbjct: 406 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTN------RQQDAQEFF 459 Query: 205 IQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEE 264 + ++ ++++ + E+ + + F E +KC +E+ + Sbjct: 460 LHLINMVERNCRSSENPN----------------------EVFRFLVEEKIKCLATEKVK 497 Query: 265 VTKGKENQLQLSCFINQEVKY-----------------------------LFTGLKLRLQ 295 T+ + +QL ++ + + L+ Sbjct: 498 YTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGA 557 Query: 296 EEITKQ--SPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLML 353 E S LQ ++ +K+++ + P YL IQ+ +F + V K+ ++ P L Sbjct: 558 PEQVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDW-VPKKLDVSIEMPEEL 616 Query: 354 DMYELCTPELQEKMVSFRSKFKDLEDKKVNQQP 386 D+ +L LQ L + P Sbjct: 617 DISQLRGTGLQPGEEELPDIAPPLVTPDEPKAP 649 Score = 50.4 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 41/109 (37%), Gaps = 13/109 (11%) Query: 374 FKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSS 433 F ++D + S+ +S+ + P G Y L A ++H G S+ Sbjct: 756 FSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGK---YQLFAFISHMGTSTMC 812 Query: 434 GHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGP 482 GHYV +K K+ W+ ++D KV + Y+ Y Sbjct: 813 GHYVCHIK-KEGRWVIYNDQKVCASEK---------PPKDLGYIYFYQR 851 >3JCR-V nrPDB Length = 565 Score = 68.9 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 63/405 (15%), Positives = 122/405 (30%), Gaps = 94/405 (23%) Query: 105 CGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAA-LRDLFDSM 163 GL N+ Y NA +Q + +VP L++ ++ +L + Sbjct: 225 VGLNNIKANDYANAVLQALSNVPPLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKL 284 Query: 164 --DKTSS-SIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIED 220 + + P +LQ + + + + Q D + + L L + Sbjct: 285 WNPRNFKAHVSPHEMLQAVVLCSKKTFQIT-----KQGDGVDFLSWFLNALHSALGGTKK 339 Query: 221 DSVK-ETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFI 279 TD S +KK D E + + + +E + + L L Sbjct: 340 KKKTIVTDVFQGSMRIFTKKLPHPDLP--AEEKEQLLHNDEYQETMVESTFMYLTL---- 393 Query: 280 NQEVKYLFTGLKLRL-----------------QEEITKQSPTLQRNALYIKSSKISRLPA 322 + L+ K +L E+ K ++K ++++LP Sbjct: 394 DLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKEYKT-----YKENFLKRFQLTKLPP 448 Query: 323 YLTIQMVRFFYKEKESVNAKVLKDVKFP-LMLDMYELCTPELQEKMVSFRSKFKDLEDKK 381 YL + RF + K V FP +D+ E + E+Q Sbjct: 449 YLIFCIKRFT--KNNFFVEKNPTIVNFPITNVDLREYLSEEVQA---------------- 490 Query: 382 VNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVK 441 + YDL A + H G+ S + + + Sbjct: 491 ------------------------------VHKNTTYDLIANIVHDGKPSEGSYRIHVLH 520 Query: 442 RKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 486 +W + D +V+ + P+ I AY+ ++ R + Sbjct: 521 HGTGKWYELQDLQVTDILPQMI-------TLSEAYIQIWKRRDND 558 >3SHQ-A nrPDB Length = 320 Score = 36.1 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 12/98 (12%) Query: 10 WGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVM---VKGGTLKDDDWGN-IKIKN 65 W +++ V+L + V + ++F T V+P RQK++ KG T D+ + +++K Sbjct: 12 WSGKEYP-VDLTDQDTVEVLRHEIFRKTQVRPERQKLLNLKYKGKTAADNVKISALELKP 70 Query: 66 GMTLLMMGSADA-------LPEEPSAKTVFVEDMTEEQ 96 L+M+GS +A LP+ +D E + Sbjct: 71 NFKLMMVGSTEADIEDACSLPDNIGEVVDDFDDADERE 108 >2VHF-A nrPDB Length = 374 Score = 35.7 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 65/183 (35%), Gaps = 22/183 (12%) Query: 285 YLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVL 344 Y + + ++ L + + K + P+ L IQM RF K Sbjct: 131 YFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPS 190 Query: 345 KDVKF-------PLM------LDMYELCTPELQEKMVSFRSK-FKDLEDKKVNQQPNTSD 390 ++ P L MYE + + + K F + +V+ P + Sbjct: 191 LELNITDLLEDTPRQCRICGGLAMYECRECYDDPDISAGKIKQFCKTCNTQVHLHPKRLN 250 Query: 391 KKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDE--WI 448 K +P K P + G C +L AVL + HYV++VK +D+ W+ Sbjct: 251 HKYNPVSLPKDLP-DWDWRHGCIPCQNMELFAVL-----CIETSHYVAFVKYGKDDSAWL 304 Query: 449 KFD 451 FD Sbjct: 305 FFD 307 >3SEZ-A nrPDB Length = 680 Score = 33.4 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 32/82 (39%), Gaps = 7/82 (8%) Query: 142 ASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDAN 201 + +T + R + ++D PP + L +F Q LQQD Sbjct: 290 FDDNRRHHRELTESFRRIDFALD------PPAGDIGLLR-EVERFPFVPADPQRLQQDCY 342 Query: 202 ECWIQMMRVLQQKLEAIEDDSV 223 E + + L+Q+L A++ V Sbjct: 343 EAYNIQVSGLEQRLRALDYPKV 364 >4MSX-A nrPDB Length = 482 Score = 32.6 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 18/40 (45%) Query: 316 KISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDM 355 +++RLP +L RF V + V+F L++ Sbjct: 367 ELTRLPQFLIFHFNRFDRNSDHPVKNRNQTLVEFSSELEI 406 >3G25-A nrPDB Length = 501 Score = 32.6 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 34/88 (38%), Gaps = 6/88 (6%) Query: 182 AFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDD-----SVKETDSSSASAATP 236 A +F + Q +++ DANE W ++ V+ + + + + T+ + Sbjct: 33 AQREFKQYFPQSGWVEHDANEIWTSVLAVMTEVINENDVRADQIAGIGITNQRETTVVWD 92 Query: 237 SKK-KSLIDQFFGVEFETTMKCTESEEE 263 + + +T C+E +++ Sbjct: 93 KHTGRPIYHAIVWQSRQTQSICSELKQQ 120 >2AKY-A nrPDB Length = 220 Score = 32.3 bits (71), Expect = 0.47, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 15/100 (15%) Query: 12 KEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLM 71 +E+F L T + + ++Q+ T + +K+M +GG + DD N+ IK Sbjct: 25 QERFHAAHLATGD---MLRSQIAKGTQLGLEAKKIMDQGGLVSDDIMVNM-IK------- 73 Query: 72 MGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLG 111 D L P+ K F+ D + A +L L G Sbjct: 74 ----DELTNNPACKNGFILDGFPRTIPQAEKLDQMLKEQG 109 >2M8S-A nrPDB Length = 97 Score = 31.9 bits (70), Expect = 0.72, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 6/78 (7%) Query: 2 PLYSVTVKWGKEKFEGVEL----NTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLK--D 55 P SV V E+++ + N++ + TGV QK++ KG +LK + Sbjct: 16 PRLSVIVTHSNERYDLLVTPQQGNSEPVVQDLAQLVEEATGVPLPFQKLIFKGKSLKEME 75 Query: 56 DDWGNIKIKNGMTLLMMG 73 + ++NG ++++G Sbjct: 76 TPLSALGMQNGCRVMLIG 93 >1WXV-A nrPDB Length = 92 Score = 31.5 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 39/83 (46%), Gaps = 6/83 (7%) Query: 5 SVTVKWGKEKFE----GVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLK--DDDW 58 +VTV EK + + +++ + + GV + QK++ KG +LK + Sbjct: 9 TVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKGKSLKEMETPL 68 Query: 59 GNIKIKNGMTLLMMGSADALPEE 81 + I++G ++++G ++ P Sbjct: 69 SALGIQDGCRVMLIGKKNSGPSS 91 >3IHM-A nrPDB Length = 430 Score = 30.7 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/126 (12%), Positives = 43/126 (34%), Gaps = 14/126 (11%) Query: 47 MVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEE--------------PSAKTVFVEDM 92 +++GG + G+ + NG T++ +G A + + + + Sbjct: 288 ILQGGVVPAFRDGHATLNNGKTIIGLGDIQATVDPVLGQGANMASYAAWILGEEILAHSV 347 Query: 93 TEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYI 152 + + + +E L T + N T+ + ++P A + R + + + Sbjct: 348 YDLRFSEHLERRRQDRVLCATRWTNFTLSALSALPPEFLAFLQILSQSREMADEFTDNFN 407 Query: 153 TAALRD 158 + Sbjct: 408 YPERQW 413 >4APL-A nrPDB Length = 431 Score = 30.3 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 28/94 (29%), Gaps = 7/94 (7%) Query: 79 PEEPSAKTVFVEDMTEEQLASAMELP-CGLTNLGNTCYMNATVQCIRSVPELKDALKRYA 137 P P K F+ED+ E P G N MN + + L + Sbjct: 70 PNRPPYKNNFLEDIPTEAEYQKSGNPLPGGFN------MNFVTPAGQRISPYPMELLEKS 123 Query: 138 GALRASGEMASAQYITAALRDLFDSMDKTSSSIP 171 ++AS E+ + S T P Sbjct: 124 SKIKASTELGKCAEFAYKTTAMDKSNQATQYRYP 157 >4YIV-A nrPDB Length = 419 Score = 29.9 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 31/94 (32%), Gaps = 7/94 (7%) Query: 79 PEEPSAKTVFVEDM-TEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYA 137 P+ P + F+ED+ TE++ + G NL N + + L Sbjct: 71 PDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNL------NFVTPSGQRISPFPMELLEKN 124 Query: 138 GALRASGEMASAQYITAALRDLFDSMDKTSSSIP 171 ++AS ++ + + T P Sbjct: 125 SNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYP 158 >1RPA-A nrPDB Length = 342 Score = 29.2 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 21/67 (31%) Query: 145 EMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECW 204 ++ + + RD + S ++ L+ L + QD E W Sbjct: 115 SLSEDRLLYLPFRDCPRFQELKSETLKSEEFLKRLQPYKSFIDTLPSLSGFEDQDLFEIW 174 Query: 205 IQMMRVL 211 ++ L Sbjct: 175 SRLYDPL 181 >6C23-A nrPDB Length = 739 Score = 28.4 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 22/146 (15%), Positives = 44/146 (30%), Gaps = 4/146 (2%) Query: 274 QLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQ---MVR 330 Q++ F L G +E+ ++ P ++ A + RLP + T ++ Sbjct: 298 QMTVFDKNRRLQLLDGEYEVAMQEM-EECPISKKRATWETILDGKRLPPFETFSQGPTLQ 356 Query: 331 FFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSD 390 F + N K + PL E E + V E + Q Sbjct: 357 FTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEK 416 Query: 391 KKSSPQKEVKYEPFSFADDIGSNNCG 416 + ++ + F + + Sbjct: 417 DTPNENRQKLRIFYQFLYNNNTRQQT 442 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.109 0.263 Lambda K H 0.267 0.0331 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,237,823 Number of Sequences: 36641 Number of extensions: 497265 Number of successful extensions: 1729 Number of sequences better than 10.0: 42 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 26 Number of HSP's that attempted gapping in prelim test: 1459 Number of HSP's gapped (non-prelim): 145 length of query: 494 length of database: 10,336,785 effective HSP length: 101 effective length of query: 393 effective length of database: 6,636,044 effective search space: 2607965292 effective search space used: 2607965292 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (28.0 bits)