BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P54136 (660 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4R3Z-B nrPDB 1368 0.0 4Q2T-A nrPDB 1221 0.0 5B63-A nrPDB 397 e-110 5JLD-A nrPDB 396 e-110 6AO8-A nrPDB 396 e-110 1F7U-A nrPDB 197 8e-51 2ZUE-A nrPDB 130 2e-30 1IQ0-A nrPDB 104 1e-22 3GDZ-A nrPDB 67 2e-11 3FNR-A nrPDB 48 2e-05 1WKB-A nrPDB 35 0.088 1WZ2-A nrPDB 35 0.095 1OBH-A nrPDB 35 0.13 5AH5-A nrPDB 33 0.32 5EES-A nrPDB 32 0.71 4QRE-A nrPDB 32 0.77 3TQO-A nrPDB 31 1.6 4ECL-A nrPDB 31 1.9 3SP1-A nrPDB 31 2.1 5DFZ-C nrPDB 30 2.4 5YBB-D nrPDB 30 3.2 2CSX-A nrPDB 30 3.6 4IIN-A nrPDB 30 3.8 5WCZ-A nrPDB 29 5.2 3D5L-A nrPDB 28 9.2 >4R3Z-B nrPDB Length = 675 Score = 1368 bits (3542), Expect = 0.0, Method: Compositional matrix adjust. Identities = 660/660 (100%), Positives = 660/660 (100%) Query: 1 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK 60 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK Sbjct: 16 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK 75 Query: 61 SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG 120 SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG Sbjct: 76 SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG 135 Query: 121 ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV 180 ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV Sbjct: 136 ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV 195 Query: 181 NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD 240 NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD Sbjct: 196 NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD 255 Query: 241 WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK 300 WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK Sbjct: 256 WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK 315 Query: 301 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG 360 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG Sbjct: 316 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG 375 Query: 361 RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF 420 RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF Sbjct: 376 RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF 435 Query: 421 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK 480 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK Sbjct: 436 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK 495 Query: 481 ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR 540 ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR Sbjct: 496 ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR 555 Query: 541 IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY 600 IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY Sbjct: 556 IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY 615 Query: 601 IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM Sbjct: 616 IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 675 >4Q2T-A nrPDB Length = 607 Score = 1221 bits (3160), Expect = 0.0, Method: Compositional matrix adjust. Identities = 588/595 (98%), Positives = 589/595 (98%) Query: 66 RNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQML 125 R +MINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQML Sbjct: 13 RGSHMASMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQML 72 Query: 126 KTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQL 185 KTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQL Sbjct: 73 KTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQL 132 Query: 186 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQF 245 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQF Sbjct: 133 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQF 192 Query: 246 GMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDIT 305 GMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDIT Sbjct: 193 GMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDIT 252 Query: 306 KAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVF 365 KAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVF Sbjct: 253 KAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVF 312 Query: 366 VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM 425 VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM Sbjct: 313 VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM 372 Query: 426 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKV 485 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKV Sbjct: 373 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKV 432 Query: 486 LTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIA 545 LTAEELNAAQTSVAYGCIKYADLS NRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIA Sbjct: 433 LTAEELNAAQTSVAYGCIKYADLSRNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIA 492 Query: 546 RLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELA 605 RLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELA Sbjct: 493 RLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELA 552 Query: 606 TAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 TAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM Sbjct: 553 TAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 607 >5B63-A nrPDB Length = 587 Score = 397 bits (1019), Expect = e-110, Method: Compositional matrix adjust. Identities = 232/599 (38%), Positives = 340/599 (56%), Gaps = 34/599 (5%) Query: 74 INIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVN 133 +NI + L E A+ AA + P V S + +FGDYQ N M +++ L + Sbjct: 10 MNIQALLSEKVRQAMIAAGAPADCEPQ-VRQSAKVQFGDYQANGMMAVAKKLG-----MA 63 Query: 134 PREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVN---GVQLPALGE 190 PR++AE + HL N KVEIAGPGFIN+ L F++E + L + GV P E Sbjct: 64 PRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATP---E 120 Query: 191 NKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIA 250 + ++VD+S+PN+AKEMHVGHLRSTIIG++ R EF G+ V+R NHVGDWGTQFGMLIA Sbjct: 121 KQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIA 180 Query: 251 HLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKL 310 L+ + + + DL+ FY+++KK +D +EEF +RA VV LQ + + W+ Sbjct: 181 WLEKQQQENAG-EMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRK 239 Query: 311 ICDVSRQELNKIYDALDVSLIE---RGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFV- 366 + D++ + YD L+V+L GES Y + IV + + +G +G +VF+ Sbjct: 240 LVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLD 299 Query: 367 -----PGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFA 421 G + + I K DGGY Y T+D+A K R AD ++Y +D+ Q H +A Sbjct: 300 EFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWA 359 Query: 422 AAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKE 481 + G Y P+ + H FG++LG+D K FKTR+G TV+L DLL E L+R+ + EK Sbjct: 360 IVRKAG-YVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKN 418 Query: 482 RDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRI 541 D + A+EL +V G +KYADLS NR DYIF +D ML GNTA Y+ YA+TR+ Sbjct: 419 PD--MPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRV 476 Query: 542 RSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYI 601 S+ R A IDEE L A +++ ++E +L +L+F E L + + H +C Y+ Sbjct: 477 LSVFRKAEIDEEQLAAA----PVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYL 532 Query: 602 YELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 Y+LA F+ FY+ C + + + +V R+ L + A + G D LGI+ V+RM Sbjct: 533 YDLAGLFSGFYEHCPILSAENE-----EVRNSRLKLAQLTAKTLKLGLDTLGIETVERM 586 >5JLD-A nrPDB Length = 599 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 220/603 (36%), Positives = 352/603 (58%), Gaps = 37/603 (6%) Query: 76 IISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPR 135 I +++ +F ++I+ +P + ++ + KFG YQCN+A+ I + + N + Sbjct: 10 ITKKIKTIFQNSIQKCFPSISEDAIVTYAN--LKFGHYQCNNAINIYKKYGKELNYENAQ 67 Query: 136 EIAENITKHLPDNECI-EKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPAL------ 188 +I+E I ++ NE I E+++ + GFI V L KD++ L L NG ++ Sbjct: 68 KISEFIISNI--NETIFEEIKSSPQGFITVKLSKDYIETSLKKLF-NGEKIDISININDI 124 Query: 189 ---GEN-KKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQ 244 EN V+VDFSSPNIAKEMHVGHLRSTIIG+SI R+FEF + R+NHVGDWGTQ Sbjct: 125 KESNENYGNVLVDFSSPNIAKEMHVGHLRSTIIGDSICRVFEFLKINTHRVNHVGDWGTQ 184 Query: 245 FGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDI 304 FGM+I +++ +P++ P + +L Y+ESKK +D ++EF+K + + + LQ + D Sbjct: 185 FGMIINYIKTHYPNFKEEMPDLSNLTSLYQESKKMYDADKEFEKSSKENAIKLQNNDEDC 244 Query: 305 TKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIV 364 W +C+ S++E +K+Y+ LD+ L GESFY ++ ++ ++ + + G I Sbjct: 245 KFVWNKLCESSKKEFDKLYNILDIKLEYVGESFYVPMLSTVLDLLKESKLL-TNIGDAIC 303 Query: 365 F-VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAA 423 + +PL + KS+GGY YD++D+AA+ RL + + +IYV D GQ HF+TIF Sbjct: 304 YQSENFKVPLFLQKSNGGYGYDSTDVAALYYRLTQLNCNCVIYVTDIGQLTHFETIFDLI 363 Query: 424 QMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKL------ 477 + W D K ++ H GFG VL ED KKFKTRSG TV+L++L+ EG +R+ L Sbjct: 364 KKTNWGD-KNAKLMHVGFGFVLNEDNKKFKTRSGTTVKLINLIKEGTERAKRDLLQRIET 422 Query: 478 KEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYA 537 K +E +++ S+ IKY DL +R +DY FS+D ML+ +GNT Y++Y Sbjct: 423 KSEEEKSYFENVDIDQLSESLCVSAIKYFDLKQHRNSDYKFSYDNMLNVKGNTGIYIIYG 482 Query: 538 FTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTL 597 ++RI SI R + I+ E + K ++ L E LG IL+FP+I IL ++ +H L Sbjct: 483 YSRICSIFRKSTINVEDISK----DELSLTSIYEINLGLHILKFPDIFYYILKNMLVHKL 538 Query: 598 CDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPV 657 +Y+Y+L T FT FY++C + + + R+LLC +++ ++LG+KP+ Sbjct: 539 AEYMYDLTTTFTAFYENCKVLNNENEKS--------RLLLCSITKSLLKLCMELLGMKPI 590 Query: 658 QRM 660 +++ Sbjct: 591 EKL 593 >6AO8-A nrPDB Length = 580 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 214/566 (37%), Positives = 329/566 (58%), Gaps = 33/566 (5%) Query: 99 PLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAG 158 P+++ P++ A+ GD+Q N MG + K+ K NPRE+A+ + L N IE E+AG Sbjct: 32 PVVLQPTKNAEHGDFQINGVMGAA-----KKAKQNPRELAQKVADALAGNAVIESAEVAG 86 Query: 159 PGFINVHLRKDFVSEQLTSLLVNG-VQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTII 217 PGFIN+ LR +F+++ + + L + + + + V++D+SSPN+AKEMHVGHLRS+II Sbjct: 87 PGFINLRLRHEFLAQNIHAALNDARFGVAKTAQPQTVVIDYSSPNLAKEMHVGHLRSSII 146 Query: 218 GESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESK 277 G+SISR+ EF G V+R NHVGDWGTQFGML+A+L ++ D + + DL+ FY+ +K Sbjct: 147 GDSISRVLEFTGNTVIRQNHVGDWGTQFGMLVAYLVEQQKD--NAAFELADLEQFYRAAK 204 Query: 278 KRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIER---G 334 RFD + F A + VV LQG + + WK D+S +YD L + L G Sbjct: 205 VRFDEDPAFADTAREYVVKLQGGDETVLALWKQFVDISLSHAQAVYDTLGLKLRPEDVAG 264 Query: 335 ESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFV------PGCSIPLTIVKSDGGYTYDTSD 388 ES Y D + + + +G DDG K+VF+ G + K GG+ Y ++D Sbjct: 265 ESKYNDDLQPVADDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFLYASTD 324 Query: 389 LAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGED 448 LA ++ R+ KA ++YVVD+ Q++HF+ +F ++ G Y P+ + GFG ++G+D Sbjct: 325 LACLRYRIGRLKAGRLLYVVDHRQALHFEQLFTTSRKAG-YLPEDAKAEFIGFGTMMGKD 383 Query: 449 KKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADL 508 K FKTRSG+TV+L+DLL E ++R+ +KEK + L A+E +V G +KYADL Sbjct: 384 GKPFKTRSGDTVKLVDLLTEAVERATALVKEKNPE--LGADEAAKIGKTVGIGAVKYADL 441 Query: 509 SHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDH 568 S NR +DY+F +D ML GNTA YL YA+TR++S+ R A + +L Sbjct: 442 SKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFRKAG-------EWDATAPTVLTE 494 Query: 569 EKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKIL 628 E +L +L+F +LQ + D + H L Y+Y+ AT F+ FY++C ++ + + Sbjct: 495 PLEKQLAAELLKFENVLQSVADTAYPHYLAAYLYQAATLFSRFYEACPILKAEGAS---- 550 Query: 629 KVNMWRMLLCEAVAAVMAKGFDILGI 654 R+ L + + +G D+LGI Sbjct: 551 --RNSRLQLAKLTGNTLKQGLDLLGI 574 >1F7U-A nrPDB Length = 607 Score = 197 bits (502), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 155/553 (28%), Positives = 261/553 (47%), Gaps = 50/553 (9%) Query: 132 VNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPA---L 188 NP+++A + P + +EKVE GP FI F+++ + ++ + L Sbjct: 81 ANPKDLAVQWAEKFPCGDFLEKVEANGP-FIQFFFNPQFLAKLVIPDILTRKEDYGSCKL 139 Query: 189 GENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGML 248 ENKKVI++FSSPNIAK H GHLRSTIIG ++ L+E G++V+R+N++GDWG QFG+L Sbjct: 140 VENKKVIIEFSSPNIAKPFHAGHLRSTIIGGFLANLYEKLGWEVIRMNYLGDWGKQFGLL 199 Query: 249 IAHLQDKFPDYLTVSPPIGDLQVFY-------KESKKRFDTEEEFKKRAYQCVVLLQGKN 301 + + V PI L Y +E E+ +A + ++ + Sbjct: 200 AVGFERYGNEEALVKDPIHHLFDVYVRINKDIEEEGDSIPLEQSTNGKAREYFKRMEDGD 259 Query: 302 PDITKAWKLICDVSRQELNKIYDALDVSL-IERGES-FYQDRMNDIVKEFEDRGFVQVDD 359 + K WK + S ++ Y L++ + GES ++ M + F+++G D Sbjct: 260 EEALKIWKRFREFSIEKYIDTYARLNIKYDVYSGESQVSKESMLKAIDLFKEKGLTHEDK 319 Query: 360 GRKIVFVPGCSIPL---TIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHF 416 G ++ + + L + KSDG Y T D+ A R + D +IYV+ + Q +H Sbjct: 320 GAVLIDLTKFNKKLGKAIVQKSDGTTLYLTRDVGAAMDRYEKYHFDKMIYVIASQQDLHA 379 Query: 417 QTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDK 476 F + +G+ K + H FG+V G TR G TV +D + E K M + Sbjct: 380 AQFFEILKQMGFEWAKDLQ--HVNFGMVQG-----MSTRKG-TVVFLDNILEETKEKMHE 431 Query: 477 LKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLY 536 + +K +K E V + D+ R+N+Y F +++ML G+T YL Y Sbjct: 432 VMKKNENKYAQIEHPEEVADLVGISAVMIQDMQGKRINNYEFKWERMLSFEGDTGPYLQY 491 Query: 537 AFTRIRSIARLA---------NIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQK 587 A +R+RS+ R A N D +L++ A K+L+ R + ++P++L+ Sbjct: 492 AHSRLRSVERNASGITQEKWINADFSLLKEPA--AKLLI---------RLLGQYPDVLRN 540 Query: 588 ILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAK 647 + T+ Y+++L + YD + G+ ++ R+ L A V+ Sbjct: 541 AIKTHEPTTVVTYLFKLTHQVSSCYDVLWV------AGQTEELATARLALYGAARQVLYN 594 Query: 648 GFDILGIKPVQRM 660 G +LG+ PV+RM Sbjct: 595 GMRLLGLTPVERM 607 >2ZUE-A nrPDB Length = 629 Score = 130 bits (327), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 163/632 (25%), Positives = 277/632 (43%), Gaps = 111/632 (17%) Query: 105 SQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDN--ECIEKVEIAGPGFI 162 + K GD+ A ++++LK P EIAE I + L N E I+ V+ A G+I Sbjct: 33 TPDPKLGDFGTPIAFKLAKLLKRP-----PIEIAEKIVEKLKLNLPEGIKDVK-AVNGYI 86 Query: 163 NVHL-RKDFVSEQLTSLLVNGVQLPA--LGENKKVIVDFSSPNIAKEMHVGHLRSTIIGE 219 NV + F + +L G + + +G+ KKVIV+ +S N K +H+GH R+ I+G+ Sbjct: 87 NVFIDYPHFARILINDILAKGDRFGSSEIGKGKKVIVEHTSVNPTKPLHMGHARNAILGD 146 Query: 220 SISRLFEFAGYDVLRLNHVGDWGTQFGMLI---AHLQDKFPDY--------LTVSPPIGD 268 ++R+ F GY+V N++ D G QF + L+++F L +P Sbjct: 147 VMARILRFLGYEVEVQNYIDDLGIQFAQVYWGYLRLKEEFERIMNELRERGLKDNPIDHA 206 Query: 269 LQVFYKESKKRFDTEEEFKK------------------------RAYQCVVLLQGKNPDI 304 L + Y E +R + E + RA G D+ Sbjct: 207 LGLLYVEVNRRLEDNPELENEIRDIMKKLESGELYGRKLAEEVVRAQMVTTYKLGVKYDL 266 Query: 305 TKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIV 364 W+ D+ R++L +I + L+ + E+FY I + + RG V D RK+ Sbjct: 267 L-VWE--SDIVRRKLFEI----ALELLSKNENFY------IPSDGKYRGAF-VMDLRKLF 312 Query: 365 FVPGCSIPLTIVK-SDGGYTYDTSDLAAIKQR--------LFEE---------------- 399 P P+ +++ SDG TY D+A + L++E Sbjct: 313 --PDMKNPILVLRRSDGTATYTGKDIAYHLWKFGKIDVDLLYKEWDSTTWTTAPDGKSMP 370 Query: 400 ----KADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTR 455 A+++I V+ Q I A Q++G+ D ++H + V + KF R Sbjct: 371 NKFGNANIVINVIGAEQKHPQLAIKYALQLLGFED-AAANLYHLAYEHV-ERPEGKFSGR 428 Query: 456 SGETVRLM--DLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRL 513 G V +++ E +KR+ + ++EK + L+ EE V G I+Y + ++ Sbjct: 429 KGTWVGFTVDEVIQEAVKRARELIEEK--NPALSDEEKAEVAEKVGIGAIRYNLIKYSPD 486 Query: 514 NDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLA-----NIDEEMLQKAARETKILLDH 568 IF ++ +L+ G +A Y+ YA R SI R A +D E L K A TK+ Sbjct: 487 KKIIFRWEDVLNFEGESAPYIQYAHARCSSILRKAEEEGIKVDPETLFKNADFTKL---S 543 Query: 569 EKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKIL 628 E+E +L + +FP I+++ D+ H + + ELA+ F +FY ++ + Sbjct: 544 ERERELVIMLSKFPRIVEQAGKDVKPHLIAWFANELASLFNKFYMDHPVLKAEEG----- 598 Query: 629 KVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 V R+LL AV V+ ++GI+ +RM Sbjct: 599 -VREARLLLVMAVEQVLKNALYLMGIEAPERM 629 >1IQ0-A nrPDB Length = 592 Score = 104 bits (259), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 147/621 (23%), Positives = 254/621 (40%), Gaps = 111/621 (17%) Query: 100 LLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGP 159 L V + + K GDY G+ KE + P+ IA+ + LP E +E+ G Sbjct: 23 LKVARAPKDKPGDY------GVPLFALAKELRKPPQAIAQELKDRLPLPEFVEEAVPVG- 75 Query: 160 GFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGE 219 G++N LR + + + + P + V+V+ +S N KE+HVGHLR+ +G+ Sbjct: 76 GYLNFRLRTEALLREALRPKAPFPRRPGV-----VLVEHTSVNPNKELHVGHLRNIALGD 130 Query: 220 SISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQ------------DKF----------- 256 +I+R+ +AG +VL LN++ D G Q + L+ D F Sbjct: 131 AIARILAYAGREVLVLNYIDDTGRQAAETLFALRHYGLTWDGKEKYDHFAGRAYVRLHQD 190 Query: 257 PDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNP--DITKAWKLICDV 314 P+Y + P I ++ + +R + EE + + + N D+ W+ D+ Sbjct: 191 PEYERLQPAIEEVL----HALERGELREEVNRILLAQMATMHALNARYDLL-VWE--SDI 243 Query: 315 SRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIP-L 373 R L + AL +L+E+ ++ R V D + +PG P Sbjct: 244 VRAGL--LQKAL--ALLEQSPHVFRPREGKYAGAL-------VMDASPV--IPGLEDPFF 290 Query: 374 TIVKSDGGYTYDTSDLA----------------------------AIKQRLFEEKADMII 405 +++S+G TY D+A A + + KA+ I Sbjct: 291 VLLRSNGTATYYAKDIAFQFWKMGILEGLRFRPYENPYYPGLRTSAPEGEAYTPKAEETI 350 Query: 406 YVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDL 465 VVD QS H Q + AA + Y + H + VL E ++ R G V + ++ Sbjct: 351 NVVDVRQS-HPQALVRAALALAGYPALAEKAHHLAYETVLLEG-RQMSGRKGLAVSVDEV 408 Query: 466 LGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLD 525 L E +R+ ++EK D E A VA G I+++ + F + + L Sbjct: 409 LEEATRRARAIVEEKNPDHPDKEE----AARMVALGAIRFSMVKTEPKKQIDFRYQEALS 464 Query: 526 DRGNTAAYLLYAFTRIRSIARLAN--IDEEMLQKAARETKILLDHEKEWKLGRCILRFPE 583 G+T Y+ YA R SI R A ++ Q E + LD +L F E Sbjct: 465 FEGDTGPYVQYAHARAHSILRKAGEWGAPDLSQATPYERALALD----------LLDFEE 514 Query: 584 ILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKILK----VNMWRMLLCE 639 + + ++ H L Y+ +LA ++ +Y++ E + +L + R+ L + Sbjct: 515 AVLEAAEERTPHVLAQYLLDLAASWNAYYNAR---ENGQPATPVLTAPEGLRELRLSLVQ 571 Query: 640 AVAAVMAKGFDILGIKPVQRM 660 ++ +A G D+LGI + M Sbjct: 572 SLQRTLATGLDLLGIPAPEVM 592 >3GDZ-A nrPDB Length = 109 Score = 67.4 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 6/108 (5%) Query: 72 NMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQK 131 N +NI + L E A+ AA + P V S + +FGDYQ N M +++ L Sbjct: 2 NAMNIQALLSEKVSQALIAAGAPADCEPQ-VRQSAKVQFGDYQANGVMAVAKKLG----- 55 Query: 132 VNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLL 179 + PR++AE + HL N KVEIAGPGFIN+ L F+++ + L Sbjct: 56 MAPRQLAEQVLSHLDLNGIANKVEIAGPGFINIFLDPAFLADNVNRAL 103 >3FNR-A nrPDB Length = 464 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 112/518 (21%), Positives = 197/518 (38%), Gaps = 89/518 (17%) Query: 166 LRKDFVSEQLTSLLVNGVQLPALGENKK--VIVDFSSPNIAKEMHVGHLRSTIIGESISR 223 L K F++E L N GE K+ ++++ S N +H+GH R + G++++R Sbjct: 3 LSKTFLNELANQALTNPNDFTK-GEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTR 61 Query: 224 LFEFAGYDVLRLNHVGDWGTQFGML-----------IAHLQDKFPDYLTVSPPIGDL--Q 270 L GY +V D G Q +L I H ++P+ I DL + Sbjct: 62 LARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESILHENVEYPEQYYKGEYIVDLAKE 121 Query: 271 VFYKESKKRFDTEE--EFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDV 328 F K K+ F E A +++L +N + K K+ VS + YDAL+ Sbjct: 122 AFEKFGKEFFSEENIPSLADWAKDKMLVLIKQNLEQAKI-KIDSYVSERSY---YDALNA 177 Query: 329 SLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSD 388 +L ES + + +E G + + +K G I++ DG TY +D Sbjct: 178 TL----ESLKEHK-----GIYEQEGKIWLASSQK-----GDEKDRVIIREDGRGTYLAAD 223 Query: 389 LAAIKQRLFEEKADMI-IYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGE 447 + K ++ I I+ D + + AA + +G+ + + ++ Sbjct: 224 IVYHKDKMSRGYGKCINIWGAD--HHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDG 281 Query: 448 DKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYAD 507 + K R+G + + D++ E + ++Y Sbjct: 282 EPYKMSKRAGNFILMSDVVDE-----------------------------IGSDALRYIF 312 Query: 508 LSHNRLNDYIFSF-DKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILL 566 LS F D +D N Y+ YA RI + A + + KA ++ L Sbjct: 313 LSKKCDTHLEFDISDLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQS---L 369 Query: 567 DHEKEWKLGRCILRFPEILQKILDDLF----LHTLCDYIYELATAFTEFYDSCYCVEKDR 622 + + G +L L+ +L+D F L + DY+ LA F +FY+ V Sbjct: 370 NQD-----GVNLLFEALNLKAVLNDAFEARALQKIPDYLKNLAANFHKFYNENKVVGSAN 424 Query: 623 QTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 + +LK L VA + F ++GI+ +M Sbjct: 425 EN-DLLK-------LFSLVALSIKTAFSLMGIEAKNKM 454 >1WKB-A nrPDB Length = 810 Score = 35.4 bits (80), Expect = 0.088, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%) Query: 192 KKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVL 233 KK + + P ++ +HVGH R+ I + I+R GY+VL Sbjct: 34 KKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVL 75 >1WZ2-A nrPDB Length = 967 Score = 35.0 bits (79), Expect = 0.095, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 24/42 (57%) Query: 192 KKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVL 233 KK + + P ++ +HVGH R+ I + I+R GY+VL Sbjct: 34 KKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVL 75 >1OBH-A nrPDB Length = 878 Score = 34.7 bits (78), Expect = 0.13, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 6/72 (8%) Query: 185 LPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQ 244 LP + V+V F P+ ++H+GHL++ +G+ ++R GY+VL H W Sbjct: 28 LPGGRGKQYVLVMFPYPS--GDLHMGHLKNYTMGDVLARFRRMQGYEVL---HPMGWDA- 81 Query: 245 FGMLIAHLQDKF 256 FG+ + KF Sbjct: 82 FGLPAENAALKF 93 >5AH5-A nrPDB Length = 822 Score = 33.5 bits (75), Expect = 0.32, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 4/56 (7%) Query: 201 PNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKF 256 P + +H+GH+R+ +G++++R+ GY VL H W + FG+ + KF Sbjct: 40 PYTSGHLHIGHVRNYSMGDTLARMQIARGYSVL---HPMGWDS-FGLPAENAARKF 91 >5EES-A nrPDB Length = 247 Score = 32.3 bits (72), Expect = 0.71, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 26/117 (22%) Query: 171 VSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGY 230 V + L+ L+ NG + V+VDF++PN +G+L I IS + G+ Sbjct: 35 VDDDLSLLVDNGAE---------VVVDFTTPNAV----MGNLEFCI-NNGISAVVGTTGF 80 Query: 231 DVLRLNHVGDW---GTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEE 284 D RL V DW G+LIA P++ +S + VF K++ + F++ E Sbjct: 81 DDARLEQVRDWLEGKDNVGVLIA------PNF-AISAVL--TMVFSKQAARFFESAE 128 >4QRE-A nrPDB Length = 547 Score = 32.3 bits (72), Expect = 0.77, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 207 MHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWG 242 +H+GH ST+ G+ I+R GYDV L + G Sbjct: 46 LHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHG 81 >3TQO-A nrPDB Length = 462 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 20/34 (58%) Query: 207 MHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD 240 MH+GH RS II + + R GY+V + ++ D Sbjct: 39 MHIGHGRSWIIFDMVVRYLRMRGYEVTFVRNITD 72 >4ECL-A nrPDB Length = 374 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 3/86 (3%) Query: 150 CIEKVEIAGPGF--INVHLRKDFVSEQLTSLLVNGVQLPALGENKKV-IVDFSSPNIAKE 206 + K E G G + +L + VS + + G++L G + ++ I+ ++SP+ AKE Sbjct: 35 AVVKAEAYGHGMYEVTTYLEQIGVSSFAVATIDEGIRLRKYGISSEILILGYTSPSRAKE 94 Query: 207 MHVGHLRSTIIGESISRLFEFAGYDV 232 + L T+I S L GYD+ Sbjct: 95 LCKYELTQTLIDYRYSLLLNKQGYDI 120 >3SP1-A nrPDB Length = 501 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 2/59 (3%) Query: 190 ENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGML 248 EN KV P + H+G+ R+ I G+ + + F GY V ++ D G G L Sbjct: 41 ENVKVYA--CGPTVYNYAHIGNFRTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDL 97 >5DFZ-C nrPDB Length = 875 Score = 30.4 bits (67), Expect = 2.4, Method: Compositional matrix adjust. Identities = 13/42 (30%), Positives = 21/42 (50%) Query: 437 FHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLK 478 FHA FG +LG+D K F ++++ G + DK + Sbjct: 746 FHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFR 787 >5YBB-D nrPDB Length = 398 Score = 30.0 bits (66), Expect = 3.2, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 155 EIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGEN 191 E A P F+ R DF++ QLT+ + G PA+ +N Sbjct: 112 EFAEPEFLFHLCRSDFITNQLTASKMRGTSYPAVTDN 148 >2CSX-A nrPDB Length = 497 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 12/35 (34%), Positives = 19/35 (54%) Query: 208 HVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWG 242 H+GH +TI ++I+R + YDV L + G Sbjct: 21 HLGHAYTTIAADTIARYYRLRDYDVFFLTGTDEHG 55 >4IIN-A nrPDB Length = 271 Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust. Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 17/136 (12%) Query: 286 FKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDI 345 F+ A Q GKN IT A K I + L + L V + R + D + + Sbjct: 20 FQSNAMQ----FTGKNVLITGASKGIGAEIAKTLASM--GLKVWINYRSNAEVADALKN- 72 Query: 346 VKEFEDRGF----VQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRL-FEEK 400 E E++G+ ++ D + F+ TIV+SDGG +Y ++ ++ +L + K Sbjct: 73 --ELEEKGYKAAVIKFDAASESDFIEAIQ---TIVQSDGGLSYLVNNAGVVRDKLAIKMK 127 Query: 401 ADMIIYVVDNGQSVHF 416 + +V+DN + F Sbjct: 128 TEDFHHVIDNNLTSAF 143 >5WCZ-A nrPDB Length = 586 Score = 29.3 bits (64), Expect = 5.2, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 8/100 (8%) Query: 230 YDVLRL---NHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEF 286 YDV+R V W I+ D FPDY T + ++ + + +E Sbjct: 207 YDVMRFWMDRGVDGWRMDVIGSISKYTD-FPDYETDHSRSYIVGRYHSNGPRLHEFIQEM 265 Query: 287 KKRA---YQCVVLLQGKNPDITKAWKLICDVSRQELNKIY 323 + Y C+ + + DI +A K D SRQELN I+ Sbjct: 266 NREVLSHYDCMTVGEANGSDIEEA-KKYTDASRQELNMIF 304 >3D5L-A nrPDB Length = 221 Score = 28.5 bits (62), Expect = 9.2, Method: Compositional matrix adjust. Identities = 25/93 (26%), Positives = 36/93 (38%), Gaps = 23/93 (24%) Query: 101 LVTPSQQAK-------FGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIE- 152 + T QQAK + YQ + I + LK + P E E I K L + I+ Sbjct: 54 IATADQQAKAYSRMLDYLSYQMRTESDIVKKLKEID---TPEEFVEPILKKLRGQQLIDD 110 Query: 153 ------------KVEIAGPGFINVHLRKDFVSE 173 ++ GPG I HLR+ + E Sbjct: 111 HAYAASYVRTMINTDLKGPGIIRQHLRQKGIGE 143 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4R3Z-B nrPDB 968 0.0 4Q2T-A nrPDB 840 0.0 5B63-A nrPDB 686 0.0 5JLD-A nrPDB 634 0.0 6AO8-A nrPDB 631 0.0 1F7U-A nrPDB 539 e-153 2ZUE-A nrPDB 482 e-136 1IQ0-A nrPDB 441 e-124 3FNR-A nrPDB 372 e-103 3GDZ-A nrPDB 129 5e-30 Sequences not found previously or not previously below threshold: 1OBH-A nrPDB 51 2e-06 3SP1-A nrPDB 50 3e-06 4QRE-A nrPDB 48 2e-05 2CSX-A nrPDB 44 3e-04 3TQO-A nrPDB 43 4e-04 5URB-A nrPDB 43 4e-04 4ARC-A nrPDB 42 7e-04 3AII-A nrPDB 39 0.005 6B1P-A nrPDB 39 0.006 1WKB-A nrPDB 39 0.007 2O5R-A nrPDB 39 0.008 1WZ2-A nrPDB 39 0.009 2X1L-A nrPDB 37 0.018 6Q8C-A nrPDB 37 0.024 5AH5-A nrPDB 37 0.027 1IYW-A nrPDB 36 0.063 5K0S-A nrPDB 34 0.14 1LI5-A nrPDB 34 0.15 1NYR-A nrPDB 34 0.19 3AKZ-B nrPDB 33 0.47 3H9B-A nrPDB 33 0.50 4FU4-A nrPDB 32 0.54 1PEX-A nrPDB 32 0.61 5UCZ-A nrPDB 32 0.79 3AL0-C nrPDB 32 0.79 4MB8-A nrPDB 32 0.87 1IRX-A nrPDB 32 1.1 6I3O-A nrPDB 32 1.2 6BRL-A nrPDB 31 1.2 5W1A-A nrPDB 31 1.3 5BNZ-A nrPDB 31 1.4 5E9F-A nrPDB 31 1.6 4G6Z-A nrPDB 31 1.8 4ZTY-A nrPDB 31 1.8 1QU3-A nrPDB 31 2.0 2JJ9-A nrPDB 31 2.5 2DHR-A nrPDB 31 2.5 5ZDO-A nrPDB 31 2.6 5L3R-A nrPDB 30 2.7 2D54-A nrPDB 30 3.1 5I4E-A nrPDB 30 3.2 4P2B-A nrPDB 30 3.5 2CV2-A nrPDB 29 5.2 4MWD-A nrPDB 29 5.3 2ZKT-A nrPDB 29 6.2 5UMD-R nrPDB 29 8.8 3EJB-B nrPDB 29 9.1 2GH9-A nrPDB 29 9.6 >4R3Z-B nrPDB Length = 675 Score = 968 bits (2501), Expect = 0.0, Method: Composition-based stats. Identities = 660/660 (100%), Positives = 660/660 (100%) Query: 1 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK 60 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK Sbjct: 16 MDVLVSECSARLLQQEEEIKSLTAEIDRLKNCGCLGASPNLEQLQEENLKLKYRLNILRK 75 Query: 61 SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG 120 SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG Sbjct: 76 SLQAERNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMG 135 Query: 121 ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV 180 ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV Sbjct: 136 ISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLV 195 Query: 181 NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD 240 NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD Sbjct: 196 NGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD 255 Query: 241 WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK 300 WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK Sbjct: 256 WGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK 315 Query: 301 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG 360 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG Sbjct: 316 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDG 375 Query: 361 RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF 420 RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF Sbjct: 376 RKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF 435 Query: 421 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK 480 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK Sbjct: 436 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEK 495 Query: 481 ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR 540 ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR Sbjct: 496 ERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTR 555 Query: 541 IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY 600 IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY Sbjct: 556 IRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDY 615 Query: 601 IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM Sbjct: 616 IYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 675 >4Q2T-A nrPDB Length = 607 Score = 840 bits (2170), Expect = 0.0, Method: Composition-based stats. Identities = 588/595 (98%), Positives = 589/595 (98%) Query: 66 RNKPTKNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQML 125 R +MINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQML Sbjct: 13 RGSHMASMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQML 72 Query: 126 KTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQL 185 KTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQL Sbjct: 73 KTKEQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQL 132 Query: 186 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQF 245 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQF Sbjct: 133 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQF 192 Query: 246 GMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDIT 305 GMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDIT Sbjct: 193 GMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDIT 252 Query: 306 KAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVF 365 KAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVF Sbjct: 253 KAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVF 312 Query: 366 VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM 425 VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM Sbjct: 313 VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM 372 Query: 426 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKV 485 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKV Sbjct: 373 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKV 432 Query: 486 LTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIA 545 LTAEELNAAQTSVAYGCIKYADLS NRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIA Sbjct: 433 LTAEELNAAQTSVAYGCIKYADLSRNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIA 492 Query: 546 RLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELA 605 RLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELA Sbjct: 493 RLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELA 552 Query: 606 TAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 TAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM Sbjct: 553 TAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 607 >5B63-A nrPDB Length = 587 Score = 686 bits (1771), Expect = 0.0, Method: Composition-based stats. Identities = 230/597 (38%), Positives = 338/597 (56%), Gaps = 28/597 (4%) Query: 73 MINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKV 132 +NI + L E A+ AA + P V S + +FGDYQ N M +++ L + Sbjct: 9 AMNIQALLSEKVRQAMIAAGAPADCEPQ-VRQSAKVQFGDYQANGMMAVAKKLG-----M 62 Query: 133 NPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENK 192 PR++AE + HL N KVEIAGPGFIN+ L F++E + L + A E + Sbjct: 63 APRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQ 122 Query: 193 KVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHL 252 ++VD+S+PN+AKEMHVGHLRSTIIG++ R EF G+ V+R NHVGDWGTQFGMLIA L Sbjct: 123 TIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWL 182 Query: 253 QDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLIC 312 + + + + DL+ FY+++KK +D +EEF +RA VV LQ + + W+ + Sbjct: 183 EKQQQENAGEM-ELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLV 241 Query: 313 DVSRQELNKIYDALDVSLIE---RGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFV--- 366 D++ + YD L+V+L GES Y + IV + + +G +G +VF+ Sbjct: 242 DITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEF 301 Query: 367 ---PGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAA 423 G + + I K DGGY Y T+D+A K R AD ++Y +D+ Q H +A Sbjct: 302 KNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIV 361 Query: 424 QMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERD 483 + G Y P+ + H FG++LG+D K FKTR+G TV+L DLL E L+R+ + EK D Sbjct: 362 RKAG-YVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPD 420 Query: 484 KVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRS 543 + A+EL +V G +KYADLS NR DYIF +D ML GNTA Y+ YA+TR+ S Sbjct: 421 --MPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLS 478 Query: 544 IARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYE 603 + R A IDEE L A +++ ++E +L +L+F E L + + H +C Y+Y+ Sbjct: 479 VFRKAEIDEEQLAAA----PVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYD 534 Query: 604 LATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 LA F+ FY+ C + + + +V R+ L + A + G D LGI+ V+RM Sbjct: 535 LAGLFSGFYEHCPILSAENE-----EVRNSRLKLAQLTAKTLKLGLDTLGIETVERM 586 >5JLD-A nrPDB Length = 599 Score = 634 bits (1634), Expect = 0.0, Method: Composition-based stats. Identities = 220/603 (36%), Positives = 352/603 (58%), Gaps = 37/603 (6%) Query: 76 IISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPR 135 I +++ +F ++I+ +P + ++ + KFG YQCN+A+ I + + N + Sbjct: 10 ITKKIKTIFQNSIQKCFPSISEDAIVTYAN--LKFGHYQCNNAINIYKKYGKELNYENAQ 67 Query: 136 EIAENITKHLPDNECI-EKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPA------- 187 +I+E I ++ NE I E+++ + GFI V L KD++ L L NG ++ Sbjct: 68 KISEFIISNI--NETIFEEIKSSPQGFITVKLSKDYIETSLKKLF-NGEKIDISININDI 124 Query: 188 --LGEN-KKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQ 244 EN V+VDFSSPNIAKEMHVGHLRSTIIG+SI R+FEF + R+NHVGDWGTQ Sbjct: 125 KESNENYGNVLVDFSSPNIAKEMHVGHLRSTIIGDSICRVFEFLKINTHRVNHVGDWGTQ 184 Query: 245 FGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDI 304 FGM+I +++ +P++ P + +L Y+ESKK +D ++EF+K + + + LQ + D Sbjct: 185 FGMIINYIKTHYPNFKEEMPDLSNLTSLYQESKKMYDADKEFEKSSKENAIKLQNNDEDC 244 Query: 305 TKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIV 364 W +C+ S++E +K+Y+ LD+ L GESFY ++ ++ ++ + + G I Sbjct: 245 KFVWNKLCESSKKEFDKLYNILDIKLEYVGESFYVPMLSTVLDLLKESKLL-TNIGDAIC 303 Query: 365 F-VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAA 423 + +PL + KS+GGY YD++D+AA+ RL + + +IYV D GQ HF+TIF Sbjct: 304 YQSENFKVPLFLQKSNGGYGYDSTDVAALYYRLTQLNCNCVIYVTDIGQLTHFETIFDLI 363 Query: 424 QMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKL------ 477 + W D K ++ H GFG VL ED KKFKTRSG TV+L++L+ EG +R+ L Sbjct: 364 KKTNWGD-KNAKLMHVGFGFVLNEDNKKFKTRSGTTVKLINLIKEGTERAKRDLLQRIET 422 Query: 478 KEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYA 537 K +E +++ S+ IKY DL +R +DY FS+D ML+ +GNT Y++Y Sbjct: 423 KSEEEKSYFENVDIDQLSESLCVSAIKYFDLKQHRNSDYKFSYDNMLNVKGNTGIYIIYG 482 Query: 538 FTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTL 597 ++RI SI R + I+ E + K ++ L E LG IL+FP+I IL ++ +H L Sbjct: 483 YSRICSIFRKSTINVEDISK----DELSLTSIYEINLGLHILKFPDIFYYILKNMLVHKL 538 Query: 598 CDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPV 657 +Y+Y+L T FT FY++C + + + R+LLC +++ ++LG+KP+ Sbjct: 539 AEYMYDLTTTFTAFYENCKVLNNENEK--------SRLLLCSITKSLLKLCMELLGMKPI 590 Query: 658 QRM 660 +++ Sbjct: 591 EKL 593 >6AO8-A nrPDB Length = 580 Score = 631 bits (1627), Expect = 0.0, Method: Composition-based stats. Identities = 214/572 (37%), Positives = 330/572 (57%), Gaps = 33/572 (5%) Query: 99 PLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDNECIEKVEIAG 158 P+++ P++ A+ GD+Q N MG ++ K NPRE+A+ + L N IE E+AG Sbjct: 32 PVVLQPTKNAEHGDFQINGVMGAAKKA-----KQNPRELAQKVADALAGNAVIESAEVAG 86 Query: 159 PGFINVHLRKDFVSEQLTSLLVN-GVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTII 217 PGFIN+ LR +F+++ + + L + + + + V++D+SSPN+AKEMHVGHLRS+II Sbjct: 87 PGFINLRLRHEFLAQNIHAALNDARFGVAKTAQPQTVVIDYSSPNLAKEMHVGHLRSSII 146 Query: 218 GESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESK 277 G+SISR+ EF G V+R NHVGDWGTQFGML+A+L ++ D + + DL+ FY+ +K Sbjct: 147 GDSISRVLEFTGNTVIRQNHVGDWGTQFGMLVAYLVEQQKDNA--AFELADLEQFYRAAK 204 Query: 278 KRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIER---G 334 RFD + F A + VV LQG + + WK D+S +YD L + L G Sbjct: 205 VRFDEDPAFADTAREYVVKLQGGDETVLALWKQFVDISLSHAQAVYDTLGLKLRPEDVAG 264 Query: 335 ESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFV------PGCSIPLTIVKSDGGYTYDTSD 388 ES Y D + + + +G DDG K+VF+ G + K GG+ Y ++D Sbjct: 265 ESKYNDDLQPVADDLVQKGLAVEDDGAKVVFLDEFKNKEGEPAAFIVQKQGGGFLYASTD 324 Query: 389 LAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGED 448 LA ++ R+ KA ++YVVD+ Q++HF+ +F ++ G Y P+ + GFG ++G+D Sbjct: 325 LACLRYRIGRLKAGRLLYVVDHRQALHFEQLFTTSRKAG-YLPEDAKAEFIGFGTMMGKD 383 Query: 449 KKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADL 508 K FKTRSG+TV+L+DLL E ++R+ +KEK + L A+E +V G +KYADL Sbjct: 384 GKPFKTRSGDTVKLVDLLTEAVERATALVKEKNPE--LGADEAAKIGKTVGIGAVKYADL 441 Query: 509 SHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDH 568 S NR +DY+F +D ML GNTA YL YA+TR++S+ R A + +L Sbjct: 442 SKNRTSDYVFDWDAMLSFEGNTAPYLQYAYTRVQSVFRKAG-------EWDATAPTVLTE 494 Query: 569 EKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGKIL 628 E +L +L+F +LQ + D + H L Y+Y+ AT F+ FY++C ++ + + Sbjct: 495 PLEKQLAAELLKFENVLQSVADTAYPHYLAAYLYQAATLFSRFYEACPILKAEGAS---- 550 Query: 629 KVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 R+ L + + +G D+LGI + M Sbjct: 551 --RNSRLQLAKLTGNTLKQGLDLLGIDVLDVM 580 >1F7U-A nrPDB Length = 607 Score = 539 bits (1388), Expect = e-153, Method: Composition-based stats. Identities = 153/544 (28%), Positives = 257/544 (47%), Gaps = 32/544 (5%) Query: 132 VNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPA---L 188 NP+++A + P + +EKVE GP FI F+++ + ++ + L Sbjct: 81 ANPKDLAVQWAEKFPCGDFLEKVEANGP-FIQFFFNPQFLAKLVIPDILTRKEDYGSCKL 139 Query: 189 GENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGML 248 ENKKVI++FSSPNIAK H GHLRSTIIG ++ L+E G++V+R+N++GDWG QFG+L Sbjct: 140 VENKKVIIEFSSPNIAKPFHAGHLRSTIIGGFLANLYEKLGWEVIRMNYLGDWGKQFGLL 199 Query: 249 IAHLQDKFPDYLTVSPPIGDLQVFY-------KESKKRFDTEEEFKKRAYQCVVLLQGKN 301 + + V PI L Y +E E+ +A + ++ + Sbjct: 200 AVGFERYGNEEALVKDPIHHLFDVYVRINKDIEEEGDSIPLEQSTNGKAREYFKRMEDGD 259 Query: 302 PDITKAWKLICDVSRQELNKIYDALDVSL-IERGES-FYQDRMNDIVKEFEDRGFVQVDD 359 + K WK + S ++ Y L++ + GES ++ M + F+++G D Sbjct: 260 EEALKIWKRFREFSIEKYIDTYARLNIKYDVYSGESQVSKESMLKAIDLFKEKGLTHEDK 319 Query: 360 GRKIVFVPGCSIPL---TIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHF 416 G ++ + + L + KSDG Y T D+ A R + D +IYV+ + Q +H Sbjct: 320 GAVLIDLTKFNKKLGKAIVQKSDGTTLYLTRDVGAAMDRYEKYHFDKMIYVIASQQDLHA 379 Query: 417 QTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDK 476 F + +G+ K + H FG+V G TR G TV +D + E K M + Sbjct: 380 AQFFEILKQMGFEWAKDLQ--HVNFGMVQG-----MSTRKG-TVVFLDNILEETKEKMHE 431 Query: 477 LKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLY 536 + +K +K E V + D+ R+N+Y F +++ML G+T YL Y Sbjct: 432 VMKKNENKYAQIEHPEEVADLVGISAVMIQDMQGKRINNYEFKWERMLSFEGDTGPYLQY 491 Query: 537 AFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHT 596 A +R+RS+ R A+ + +K LL L R + ++P++L+ + T Sbjct: 492 AHSRLRSVERNASGITQ--EKWINADFSLLKEPAAKLLIRLLGQYPDVLRNAIKTHEPTT 549 Query: 597 LCDYIYELATAFTEFYDSCYCVEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKP 656 + Y+++L + YD + G+ ++ R+ L A V+ G +LG+ P Sbjct: 550 VVTYLFKLTHQVSSCYDVLWV------AGQTEELATARLALYGAARQVLYNGMRLLGLTP 603 Query: 657 VQRM 660 V+RM Sbjct: 604 VERM 607 >2ZUE-A nrPDB Length = 629 Score = 482 bits (1240), Expect = e-136, Method: Composition-based stats. Identities = 159/643 (24%), Positives = 274/643 (42%), Gaps = 109/643 (16%) Query: 93 PDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAENITKHLPDN--EC 150 + + + K GD+ A ++++LK P EIAE I + L N E Sbjct: 21 APQWEGEIELKETPDPKLGDFGTPIAFKLAKLLKRP-----PIEIAEKIVEKLKLNLPEG 75 Query: 151 IEKVEIAGPGFINVHL-RKDFVSEQLTSLLVNGVQLPA--LGENKKVIVDFSSPNIAKEM 207 I+ V+ A G+INV + F + +L G + + +G+ KKVIV+ +S N K + Sbjct: 76 IKDVK-AVNGYINVFIDYPHFARILINDILAKGDRFGSSEIGKGKKVIVEHTSVNPTKPL 134 Query: 208 HVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLI---AHLQDKFPDY----- 259 H+GH R+ I+G+ ++R+ F GY+V N++ D G QF + L+++F Sbjct: 135 HMGHARNAILGDVMARILRFLGYEVEVQNYIDDLGIQFAQVYWGYLRLKEEFERIMNELR 194 Query: 260 ---LTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITK---------- 306 L +P L + Y E +R + E + + L+ K Sbjct: 195 ERGLKDNPIDHALGLLYVEVNRRLEDNPELENEIRDIMKKLESGELYGRKLAEEVVRAQM 254 Query: 307 -------------AWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRG 353 W+ D+ R++L +I + L+ + E+FY I + + RG Sbjct: 255 VTTYKLGVKYDLLVWE--SDIVRRKLFEI----ALELLSKNENFY------IPSDGKYRG 302 Query: 354 FVQVDDGRKIVFVPGCSIPLTIVK-SDGGYTYDTSDLAAIKQRLFE-------------- 398 V D RK+ P P+ +++ SDG TY D+A + + Sbjct: 303 AF-VMDLRKLF--PDMKNPILVLRRSDGTATYTGKDIAYHLWKFGKIDVDLLYKEWDSTT 359 Query: 399 --------------EKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVV 444 A+++I V+ Q I A Q++G+ D ++H + V Sbjct: 360 WTTAPDGKSMPNKFGNANIVINVIGAEQKHPQLAIKYALQLLGFEDA-AANLYHLAYEHV 418 Query: 445 LGEDKKKFKTRSGETVRLM--DLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGC 502 + KF R G V +++ E +KR+ + ++EK L+ EE V G Sbjct: 419 -ERPEGKFSGRKGTWVGFTVDEVIQEAVKRARELIEEKNP--ALSDEEKAEVAEKVGIGA 475 Query: 503 IKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLA-----NIDEEMLQK 557 I+Y + ++ IF ++ +L+ G +A Y+ YA R SI R A +D E L K Sbjct: 476 IRYNLIKYSPDKKIIFRWEDVLNFEGESAPYIQYAHARCSSILRKAEEEGIKVDPETLFK 535 Query: 558 AARETKILLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYC 617 A TK+ E+E +L + +FP I+++ D+ H + + ELA+ F +FY Sbjct: 536 NADFTKL---SERERELVIMLSKFPRIVEQAGKDVKPHLIAWFANELASLFNKFYMDHPV 592 Query: 618 VEKDRQTGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 ++ + V R+LL AV V+ ++GI+ +RM Sbjct: 593 LKAEEG------VREARLLLVMAVEQVLKNALYLMGIEAPERM 629 >1IQ0-A nrPDB Length = 592 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 148/640 (23%), Positives = 257/640 (40%), Gaps = 112/640 (17%) Query: 80 LQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQKVNPREIAE 139 L+E A+K + L V + + K GDY G+ KE + P+ IA+ Sbjct: 6 LEEAIAQALKEMGVPVR---LKVARAPKDKPGDY------GVPLFALAKELRKPPQAIAQ 56 Query: 140 NITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFS 199 + LP E +E+ G G++N LR + + + + P + V+V+ + Sbjct: 57 ELKDRLPLPEFVEEAVPVG-GYLNFRLRTEALLREALRPKAPFPRRPGV-----VLVEHT 110 Query: 200 SPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKF--- 256 S N KE+HVGHLR+ +G++I+R+ +AG +VL LN++ D G Q + L+ Sbjct: 111 SVNPNKELHVGHLRNIALGDAIARILAYAGREVLVLNYIDDTGRQAAETLFALRHYGLTW 170 Query: 257 --------------------PDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVL 296 P+Y + P I ++ + +R + EE + + Sbjct: 171 DGKEKYDHFAGRAYVRLHQDPEYERLQPAIEEVL----HALERGELREEVNRILLAQMAT 226 Query: 297 LQGKNP-DITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFV 355 + N W+ D+ R L + AL +L+E+ ++ R Sbjct: 227 MHALNARYDLLVWE--SDIVRAGL--LQKAL--ALLEQSPHVFRPREGKYAGAL------ 274 Query: 356 QVDDGRKIVFVPGCSIP-LTIVKSDGGYTYDTSDLA------------------------ 390 V D ++ PG P +++S+G TY D+A Sbjct: 275 -VMDASPVI--PGLEDPFFVLLRSNGTATYYAKDIAFQFWKMGILEGLRFRPYENPYYPG 331 Query: 391 ----AIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLG 446 A + + KA+ I VVD QS H Q + AA + Y + H + VL Sbjct: 332 LRTSAPEGEAYTPKAEETINVVDVRQS-HPQALVRAALALAGYPALAEKAHHLAYETVLL 390 Query: 447 EDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYA 506 E ++ R G V + ++L E +R+ ++EK D E A VA G I+++ Sbjct: 391 E-GRQMSGRKGLAVSVDEVLEEATRRARAIVEEKNPDHPDKEE----AARMVALGAIRFS 445 Query: 507 DLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLAN--IDEEMLQKAARETKI 564 + F + + L G+T Y+ YA R SI R A ++ Q E + Sbjct: 446 MVKTEPKKQIDFRYQEALSFEGDTGPYVQYAHARAHSILRKAGEWGAPDLSQATPYERAL 505 Query: 565 LLDHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQT 624 LD +L F E + + ++ H L Y+ +LA ++ +Y++ E + Sbjct: 506 ALD----------LLDFEEAVLEAAEERTPHVLAQYLLDLAASWNAYYNAR---ENGQPA 552 Query: 625 GKILK----VNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 +L + R+ L +++ +A G D+LGI + M Sbjct: 553 TPVLTAPEGLRELRLSLVQSLQRTLATGLDLLGIPAPEVM 592 >3FNR-A nrPDB Length = 464 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 107/517 (20%), Positives = 194/517 (37%), Gaps = 87/517 (16%) Query: 166 LRKDFVSEQLTSLLVNGVQLPALGENKK-VIVDFSSPNIAKEMHVGHLRSTIIGESISRL 224 L K F++E L N + ++ ++++ S N +H+GH R + G++++RL Sbjct: 3 LSKTFLNELANQALTNPNDFTKGEKKQESFLLEYVSANPTGPLHIGHARGAVFGDTLTRL 62 Query: 225 FEFAGYDVLRLNHVGDWGTQFGML-----------IAHLQDKFPDYLTVSPPIGDL--QV 271 GY +V D G Q +L I H ++P+ I DL + Sbjct: 63 ARHLGYKFNTEYYVNDAGNQIYLLGLSILLSVKESILHENVEYPEQYYKGEYIVDLAKEA 122 Query: 272 FYKESKKRFDTE--EEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVS 329 F K K+ F E A +++L +N + K K+ VS + YDAL+ + Sbjct: 123 FEKFGKEFFSEENIPSLADWAKDKMLVLIKQNLEQAKI-KIDSYVSERSY---YDALNAT 178 Query: 330 LIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSDL 389 L ES + + +E G + + +K G I++ DG TY +D+ Sbjct: 179 L----ESLKEHK-----GIYEQEGKIWLASSQK-----GDEKDRVIIREDGRGTYLAADI 224 Query: 390 AAIKQRLFEEKADMI-IYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGED 448 K ++ I I+ D + + AA + +G+ + + ++ + Sbjct: 225 VYHKDKMSRGYGKCINIWGAD--HHGYIPRMKAAMEFLGFDSNNLEIILAQMVSLLKDGE 282 Query: 449 KKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADL 508 K R+G + + D++ E + ++Y L Sbjct: 283 PYKMSKRAGNFILMSDVVDE-----------------------------IGSDALRYIFL 313 Query: 509 SHNRLNDYIFSF-DKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLD 567 S F D +D N Y+ YA RI + A + + KA ++ L+ Sbjct: 314 SKKCDTHLEFDISDLQKEDSSNPVYYINYAHARIHQVFAKAGKKIDDVMKADLQS---LN 370 Query: 568 HEKEWKLGRCILRFPEILQKILDDLF----LHTLCDYIYELATAFTEFYDSCYCVEKDRQ 623 + G +L L+ +L+D F L + DY+ LA F +FY+ V + Sbjct: 371 QD-----GVNLLFEALNLKAVLNDAFEARALQKIPDYLKNLAANFHKFYNENKVVGSANE 425 Query: 624 TGKILKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM 660 + L VA + F ++GI+ +M Sbjct: 426 NDL--------LKLFSLVALSIKTAFSLMGIEAKNKM 454 >3GDZ-A nrPDB Length = 109 Score = 129 bits (323), Expect = 5e-30, Method: Composition-based stats. Identities = 40/109 (36%), Positives = 58/109 (53%), Gaps = 6/109 (5%) Query: 71 KNMINIISRLQEVFGHAIKAAYPDLENPPLLVTPSQQAKFGDYQCNSAMGISQMLKTKEQ 130 N +NI + L E A+ AA + P V S + +FGDYQ N M +++ L Sbjct: 1 SNAMNIQALLSEKVSQALIAAGAPADCEPQ-VRQSAKVQFGDYQANGVMAVAKKLG---- 55 Query: 131 KVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLL 179 + PR++AE + HL N KVEIAGPGFIN+ L F+++ + L Sbjct: 56 -MAPRQLAEQVLSHLDLNGIANKVEIAGPGFINIFLDPAFLADNVNRAL 103 >1OBH-A nrPDB Length = 878 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 46/124 (37%), Gaps = 7/124 (5%) Query: 179 LVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHV 238 + LP + V+V F P + ++H+GHL++ +G+ ++R GY+VL Sbjct: 22 FMKAKDLPGGRGKQYVLVMF--PYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGW 79 Query: 239 GDWGTQFGMLIAHLQDK-----FPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQC 293 +G + + + + + Y ++ E E+ + Sbjct: 80 DAFGLPAENAALKFGVHPKDWTYANIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWI 139 Query: 294 VVLL 297 + + Sbjct: 140 FLKM 143 >3SP1-A nrPDB Length = 501 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 55/322 (17%), Positives = 102/322 (31%), Gaps = 24/322 (7%) Query: 153 KVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHL 212 + + GPG + + L L + V V P + H+G+ Sbjct: 13 EAQTQGPGSMILKLYN-----------TRTKDFSELTNFENVKVYACGPTVYNYAHIGNF 61 Query: 213 RSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVF 272 R+ I G+ + + F GY V ++ D G G L + ++ F Sbjct: 62 RTYIFGDLLIKTLRFLGYKVNYAMNITDIGHLTGDLDDGEDKVAKTAREKGLTVYEISEF 121 Query: 273 YKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVS-LI 331 + E+ F+ + V++ P + + K++ + + D S Sbjct: 122 FTEA--FFNDCRKLNIVYPDKVLVASKHIPIMIEVVKILEEKKITYFSNGNVYFDTSCFK 179 Query: 332 ERGESF---YQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYDTSD 388 GE D+ + + D+ D S G+ Y + Sbjct: 180 SYGEMAGIDLIDKDMTLPRVDVDKFKRNKTDFVLWFTNSKFKDQEMKWDSPWGFGYPSWH 239 Query: 389 L--AAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLG 446 L AA+ F++ D+ + VD+ H I A + V H F ++ Sbjct: 240 LECAAMNLEYFKDALDIHLGGVDHIGVHHINEIAIAECFLNKKWCDV--FVHGEFLIM-- 295 Query: 447 EDKKKFKTRSGETVRLMDLLGE 468 D K G + + DL + Sbjct: 296 -DYNKMSKSRGNFITVKDLEDQ 316 >4QRE-A nrPDB Length = 547 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 62/345 (17%), Positives = 114/345 (33%), Gaps = 56/345 (16%) Query: 203 IAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQ------------------ 244 + +H+GH ST+ G+ I+R GYDV L + G + Sbjct: 42 PSGNLHIGHAYSTVAGDVIARYKRMQGYDVRYLTGTDEHGQKIQEKAQKAGKTEIEYLDE 101 Query: 245 ----FGMLIAHLQDKFPDYLTVSP--------------------PIGDLQVFYKESKKRF 280 L A L+ D++ + +G+ + +Y + + Sbjct: 102 MIAGIKQLWAKLEISNDDFIRTTEERHKHVVEQVFERLLKQGDIYLGEYEGWYSVPDETY 161 Query: 281 DTEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQD 340 TE + Y+ ++ GK+PD +L+ + S Y + ++ F Q Sbjct: 162 YTESQLVDPQYENGKIIGGKSPDSGHEVELVKEESYFFNISKYTDRLLEFYDQNPDFIQP 221 Query: 341 --RMNDIVKEFEDRGFVQVDDGRKI----VFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQ 394 R N+++ F G + R V VP + V D Y ++ L + Sbjct: 222 PSRKNEMINNFIKPGLADLAVSRTSFNWGVHVPSNPKHVVYVWIDALVNYISA-LGYLSD 280 Query: 395 --RLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKF 452 LF + I+++ + V F +I ++ P +VF G+ ++ K Sbjct: 281 DESLFNKYWPADIHLM-AKEIVRFHSIIWPILLMALDLPLPKKVFAHGWILMKDG---KM 336 Query: 453 KTRSGETVRLMDLLGE-GLKRSMDKLKEKERDKVLTAEELNAAQT 496 G V L+ GL + L + A Sbjct: 337 SKSKGNVVDPNILIDRYGLDATRYYLMRELPFGSDGVFTPEAFVE 381 >2CSX-A nrPDB Length = 497 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 85/500 (17%), Positives = 166/500 (33%), Gaps = 107/500 (21%) Query: 208 HVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWG----------------------TQF 245 H+GH +TI ++I+R + YDV L + G +F Sbjct: 21 HLGHAYTTIAADTIARYYRLRDYDVFFLTGTDEHGLKIQKKAEELGISPKELVDRNAERF 80 Query: 246 GMLIAHLQDKFPDYLTVSPPIGD--LQVFYKESKKRFDTE-EEFKKR----AYQCVVLLQ 298 L L+ ++ ++ + P +Q ++E KR D E++ + + Sbjct: 81 KKLWEFLKIEYTKFIRTTDPYHVKFVQKVFEECYKRGDIYLGEYEGWYCVGCEEFKSEAE 140 Query: 299 GKNPDITKAWKLICDVSRQ-----ELNKIYDALDVSLIERGESFYQD--RMNDIVKEFED 351 + C+ ++ L+K D L + L E+ F Q R N+I+ + Sbjct: 141 LAEDHTCPIHQKKCEYIKEPSYFFRLSKYQDKL-LELYEKNPEFIQPDYRRNEIISFVKQ 199 Query: 352 RGFVQVDDGRKIVFVP-GCSIPL-----TIVKSDGGYTYDTSDLAAIKQRLFEEKADMII 405 G + R V G +P V D + Y ++A++ ++ + Sbjct: 200 -GLKDLSVTRPRSRVKWGIPVPFDPEHTIYVWFDALFNY----ISALEDKVEIYWPADLH 254 Query: 406 YVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDL 465 V + H A +G+ PK +VF G+ V + KK G V ++ Sbjct: 255 LVGKDILRFHTVYWPAFLMSLGYELPK--KVFAHGWWTV---EGKKMSKTLGNVVDPYEV 309 Query: 466 LGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRL-NDYIFSFDKML 524 + E ++Y L D FS +L Sbjct: 310 VQE-----------------------------YGLDEVRYFLLREVPFGQDGDFSKKAIL 340 Query: 525 D-DRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPE 583 + G A + ++R+ ++A E + KI + K ++ + F + Sbjct: 341 NRINGELANEIGNLYSRVVNMAHKFLGGEVSGARDEEYAKIAQESIKNYENYMEKVNFYK 400 Query: 584 ILQKILDDLFLHTLCDYIYELATAFTEFYDSC--YCVEKDRQTGKILKVNMWRM------ 635 +++IL + ++ D + + K+R+ ++ KV + Sbjct: 401 AIEEILK-------------FTSYLNKYVDEKQPWALNKERKKEELQKVLYALVDGLFVL 447 Query: 636 --LLCEAVAAVMAKGFDILG 653 LL M + +LG Sbjct: 448 THLLYPITPNKMKEALQMLG 467 >3TQO-A nrPDB Length = 462 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 75/401 (18%), Positives = 135/401 (33%), Gaps = 56/401 (13%) Query: 170 FVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAG 229 +S ++ + L ++ E+ KV + + MH+GH RS II + + R G Sbjct: 2 AMSVKIFNSLTKQKEIFKPIESGKVKLYVCGMTVYDYMHIGHGRSWIIFDMVVRYLRMRG 61 Query: 230 YDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKR 289 Y+V + ++ D + + A + P L +Q+ +++ K + + R Sbjct: 62 YEVTFVRNITDIDDKI-IKRAGENKESPAALAERF----IQILHEDEKALRVLSPDQEPR 116 Query: 290 AYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGES---FYQDRMNDIV 346 A Q V P+I K I LD G++ F+ R Sbjct: 117 ATQYV-------PEIIKL--------------IQKLLDNQYAYTGQNGDVFFDVRRFKDY 155 Query: 347 KEFEDRGFVQVDDGRK--IVFVPGCSIPLTIVKS-------------DGGYTYDTSDLAA 391 + R ++ G + + + + K +G + A Sbjct: 156 GKLSHRHLDELQAGARVEVSDSKRDPLDFVLWKKAKPGEPKWDSPWGEGRPGWHIECSAM 215 Query: 392 IKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKK 451 L + D+ +D H I A G P V HAG +L +K+K Sbjct: 216 SSSILGQP-FDIHGGGLDLKFPHHENEI--AQSEAGEEKPFVKLWMHAG---LLEINKEK 269 Query: 452 FKTRSGETVRLMDLLGEG-LKRSMDKLKEKERDKVLTAEELNAAQTSVAYGCIKYAD--- 507 G + + + L E ++ L L+ + N +A A Sbjct: 270 MSKSLGNIISIREALKESDVEVLRYFLLSGHYRNPLSYSKENLENGRLALERFYLALRGL 329 Query: 508 --LSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIAR 546 ++H + + Y F + +DD NT F +R I R Sbjct: 330 PVVNHEKTSSYTDRFYEAMDDDFNTPIAFALLFEMVREINR 370 >5URB-A nrPDB Length = 567 Score = 42.9 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 72/488 (14%), Positives = 136/488 (27%), Gaps = 95/488 (19%) Query: 184 QLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHV--GDW 241 Q G +K++V + P +H+GHL I + R G+DV +V D Sbjct: 15 QTQGPGSMRKILVTNALPYANGPIHMGHLLGYIQADIWVRAMRAMGHDV---TYVCADDA 71 Query: 242 GTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESK--KRFDTEEEFKKRAYQ---CVVL 296 ML A P+ + ++ F +D+ +A + Sbjct: 72 HGTAIMLRAEANGISPEEQIANVQKEHIRDFDGFGVHFDHYDSTHSDANKARSTDIYIKN 131 Query: 297 LQGKNPDITKAWKLI-----------------------------CDVSRQELNKIY---- 323 + N + +L C+V N Sbjct: 132 REAGNIAVRPVTQLFDPEKGMFLSDRFIKGTCPKCKSEDQYGDSCEVCGTTYNATELLNP 191 Query: 324 --DALDVSLIERGESFYQDRMNDIVKEFE----DRGFVQVDDGRKI-------------- 363 + +E+ Y ++ + + + D G + + K+ Sbjct: 192 RSTLSGATPVEKSSDHYFFKLPNFAEYLQKWTRDEGRLPLSIANKLDEWFEAGLADWDIS 251 Query: 364 -------VFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHF 416 +P V D Y +S IK + + D + D+ V+ Sbjct: 252 RDAPYFGFEIPDAPNKYFYVWVDAPIGYMSSFENYIKTKRPDLNFDD-FWKKDSQNEVYH 310 Query: 417 QTIFAAAQMIGWYDPKVTR---------VFHAGFGVVLGEDKKKFKTRSGETVRLMDLLG 467 + P + +F GF V G+ K G ++ L Sbjct: 311 FIGKDIVYFHALFWPAMLEGANYRTPTGLFVNGFLTVNGQ---KMSKSRGTFIKAETYLQ 367 Query: 468 EGLKRSMD-----KLKEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFSFDK 522 + KL +K D L ++ S G K +++ SF+ Sbjct: 368 HLNPEYLRYYFASKLSDKVEDSDLNLDDFVQKVNSDLVG--KVVNIASRCAKFINSSFNN 425 Query: 523 MLDD---RGNTAAYLLYAFTRIRSIA--RLANIDEEMLQKAARETKILLDHEKEWKLGRC 577 L + + A I + R + + A +D +K W L + Sbjct: 426 TLSSTCAESDLVQSFIDAGDSIAAAYEAREFSTAIREIMALADRANQYIDEKKPWALAKQ 485 Query: 578 ILRFPEIL 585 + ++L Sbjct: 486 EGQEQQVL 493 >4ARC-A nrPDB Length = 880 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 38/105 (36%), Gaps = 5/105 (4%) Query: 201 PNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQD-----K 255 P + +H+GH+R+ IG+ I+R G +VL+ +G Sbjct: 62 PYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWT 121 Query: 256 FPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK 300 + + + + L Y S++ E+ + + L K Sbjct: 122 YDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKK 166 >3AII-A nrPDB Length = 553 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 28/47 (59%), Gaps = 3/47 (6%) Query: 189 GENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRL 235 G +V++ F +PN + +H+GH R+ I+ +R ++ G +LR+ Sbjct: 92 GVKGEVVLRF-APNPSGPLHIGHARAAILNHEYAR--KYDGRLILRI 135 >6B1P-A nrPDB Length = 471 Score = 39.0 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 53/282 (18%), Positives = 96/282 (34%), Gaps = 44/282 (15%) Query: 193 KVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHL 252 +IV +P+ +H+G LR+ I +R + G LR+ D + Sbjct: 10 SLIVTRFAPSPTGYLHIGGLRTAIFNYLFARANQ--GKFFLRIEDT-DLSRNSIEAANAI 66 Query: 253 QDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLIC 312 + F D ++ Y+ KRF+ + + L ++ C Sbjct: 67 IEAFKWVGLE----YDGEILYQ--SKRFE-------IYKEYIQKLLDEDKAY------YC 107 Query: 313 DVSRQELNKIYDALDV-SLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCS- 370 +S+ EL+ + + R ++ Y+D K E ++V I F G Sbjct: 108 YMSKDELDALREEQKARKETPRYDNRYRDFKGTPPKGIEPVVRIKVPQNEVIGFNDGVKG 167 Query: 371 ---------IPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFA 421 I +SDG TY + I D +I D+ + Q + Sbjct: 168 EVKVNTNELDDFIIARSDGTPTY---NFVVIVDDALMGITD-VIRGDDHLSNTPKQIVLY 223 Query: 422 AAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLM 463 + + + P FH ++L E+ +K R G T + Sbjct: 224 --KALNFKIPN---FFHV--PMILNEEGQKLSKRHGATNVMD 258 >1WKB-A nrPDB Length = 810 Score = 39.0 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 190 ENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVL 233 + KK + + P ++ +HVGH R+ I + I+R GY+VL Sbjct: 32 KEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVL 75 >2O5R-A nrPDB Length = 481 Score = 38.6 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 46/281 (16%), Positives = 94/281 (33%), Gaps = 50/281 (17%) Query: 200 SPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDY 259 +P+ +HVG R+ + +R + G +LR+ + + ++ + Sbjct: 19 APSPTGFLHVGGARTALFNFLFAR--KEKGKFILRIEDTD---------LERSEREYEE- 66 Query: 260 LTVSPPIGDLQVFYKES----KKRFDTEE-EFKKRAYQCVVLLQG-KNPDITKAWKLICD 313 + + L + + E + E + + L A+ + Sbjct: 67 -KLMESLRWLGLLWDEGPDVGGDHGPYRQSERVEIYREHAERLVKEGKAYYVYAYPEEIE 125 Query: 314 VSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGF------------VQVDDGR 361 R++L A E F + + +E+E++G ++D Sbjct: 126 EMREKLLSEGKAPH----YSQEMFEKFDTPERRREYEEKGLRPAVFFKMPRKDYVLNDVV 181 Query: 362 K--IVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTI 419 K +VF G I++S+G TY + A + + E I +V+ + Sbjct: 182 KGEVVFKTGAIGDFVIMRSNGLPTY---NFACVVDDMLME----ITHVIRGDDH-----L 229 Query: 420 FAAAQMIGWYDP-KVTRVFHAGFGVVLGEDKKKFKTRSGET 459 + + Y+ + A +LG D KK R G T Sbjct: 230 SNTLRQLALYEAFEKAPPVFAHVSTILGPDGKKLSKRHGAT 270 >1WZ2-A nrPDB Length = 967 Score = 38.6 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 25/44 (56%) Query: 190 ENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVL 233 + KK + + P ++ +HVGH R+ I + I+R GY+VL Sbjct: 32 KEKKFYITVAFPYLSGHLHVGHARTYTIPDVIARFKRMQGYNVL 75 >2X1L-A nrPDB Length = 524 Score = 37.5 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 26/151 (17%), Positives = 42/151 (27%), Gaps = 18/151 (11%) Query: 203 IAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTV 262 H+GH I ++I+R GYDV L G + A Sbjct: 23 PNGVPHIGHAYEYIATDAIARFKRLDGYDVRYLTGTDVHGQKMAETAA----------KE 72 Query: 263 SPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKN--PDITKAWKLIC---DVSRQ 317 P +L + + F +E ++ + + WK + D+ Sbjct: 73 GIPAAELA---RRNSDVFQRLQEKLNISFDRFIRTSDADHYEASKAIWKRMADAGDIYLD 129 Query: 318 ELNKIYDALDVSLIERGESFYQDRMNDIVKE 348 Y D E+ Q I E Sbjct: 130 AYKGWYSIRDERFFTENETTEQPDGTRIATE 160 >6Q8C-A nrPDB Length = 877 Score = 37.1 bits (84), Expect = 0.024, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 22/33 (66%) Query: 201 PNIAKEMHVGHLRSTIIGESISRLFEFAGYDVL 233 P + ++H+GH+R+ IG+ +SR G++V+ Sbjct: 43 PYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVM 75 >5AH5-A nrPDB Length = 822 Score = 37.1 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 34/194 (17%), Positives = 66/194 (34%), Gaps = 13/194 (6%) Query: 183 VQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWG 242 KK V P + +H+GH+R+ +G++++R+ GY VL H W Sbjct: 22 FDWDPSSPGKKFYVLEMFPYTSGHLHIGHVRNYSMGDTLARMQIARGYSVL---HPMGWD 78 Query: 243 TQFGMLIAHLQDKFPDY--LTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGK 300 + FG+ + KF + I ++ + + E + V+ Q Sbjct: 79 S-FGLPAENAARKFGTHPAKFTQDAIDSMKRSMMQLGFGYSWANELATCSPTYVLAQQKL 137 Query: 301 NPDITK---AWKLICDV----SRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRG 353 D+ + ++ V Q + +D G + Y+ R + Sbjct: 138 FLDLYRKGLIYRDDTYVYWDPVEQTVLAAEQVIDGKGWRSGAAVYKRRTPQWFVDIRSYA 197 Query: 354 FVQVDDGRKIVFVP 367 +DD + P Sbjct: 198 DRLLDDLESLEGWP 211 >1IYW-A nrPDB Length = 862 Score = 35.9 bits (81), Expect = 0.063, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 54/175 (30%), Gaps = 10/175 (5%) Query: 178 LLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNH 237 V P G+ VI PN+ +H+GH + +++ R G++ + L Sbjct: 21 AKNPFVANPKSGKPPFVIF-MPPPNVTGSLHMGHALDNSLQDALIRYKRMRGFEAVWLPG 79 Query: 238 VGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLL 297 G +++ L L DL K ++ + +EE + + L Sbjct: 80 TDHAGIATQVVVERL------LLKEGKTRHDLGR-EKFLERVWQWKEESGGTILKQLKRL 132 Query: 298 QGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQ--DRMNDIVKEFE 350 +A+ + SR L R R + + E Sbjct: 133 GASADWSREAFTMDEKRSRAVRYAFSRYYHEGLAYRAPRLVNWCPRCETTLSDLE 187 >5K0S-A nrPDB Length = 536 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 65/351 (18%), Positives = 108/351 (30%), Gaps = 70/351 (19%) Query: 186 PALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWG--- 242 P +K + + + H+GH I ++++R G DV L + G Sbjct: 19 PGSMSREKYYITTAIAYPNGKPHIGHAYELIATDAMARFQRLNGMDVYFLTGTDEHGIKM 78 Query: 243 ----------------------TQFGMLIA-----HLQDKFPDYLTVSPPI--------- 266 + ++ +++ + S I Sbjct: 79 LQSARKEGITPRDLADRNTSAFRRMAEVLNSSNDDYIRTSEERHYKASQAIWQAMVANGD 138 Query: 267 ---GDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAW-KLICDVSRQELNKI 322 G +Y + + EEE + RA QG + W + R L+ Sbjct: 139 IYKGGYAGWYSVRDEAYYGEEETEVRADGVRYGPQGTPVE----WVEEESYFFR--LSAY 192 Query: 323 YDALDVSLIERGESFYQD--RMNDIVKEFEDRGFVQVDDGRKIVF----VPGCSIPLTIV 376 D L + L E F R N+IV F G + R VPG + V Sbjct: 193 QDKL-LDLYENNPGFIMPAERRNEIVS-FVKSGLKDLSISRTTFDWGIPVPGDEKHVMYV 250 Query: 377 KSDGGYTYDTS----DLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDPK 432 D Y T+ D + + A +I + +V++ +AQ+ P Sbjct: 251 WVDALTNYITALGYPDTTDERWAYWPANAHIIGKDISRFHAVYWPAFLMSAQL-----PL 305 Query: 433 VTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGE-GLKRSMDKLKEKER 482 RVF GF GE K G + +L+ GL + L + Sbjct: 306 PKRVFAHGFLFNRGE---KMSKSVGNVIDPFELVERYGLDQLRYFLMREVP 353 >1LI5-A nrPDB Length = 461 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 19/33 (57%) Query: 208 HVGHLRSTIIGESISRLFEFAGYDVLRLNHVGD 240 H+GH R+ + + ++R F GY + + ++ D Sbjct: 37 HIGHGRTFVAFDVVARYLRFLGYKLKYVRNITD 69 >1NYR-A nrPDB Length = 645 Score = 34.0 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 28/166 (16%), Positives = 52/166 (31%), Gaps = 21/166 (12%) Query: 268 DLQVFYKESKKRFDTEEEFKKR--AYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDA 325 D + K K+ + + +++ + L + +LI + E +Y Sbjct: 118 DFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKL---ELIDAIPEDENVTLYSQ 174 Query: 326 LDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPLTIVKSDGGYTYD 385 D + + RG K G G S + + G +D Sbjct: 175 GDFTDLCRGVHVPSTAKIKEFKLLSTAGAYW----------RGDSNNKMLQRIYGTAFFD 224 Query: 386 TSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGWYDP 431 +L A Q L E K D+ + +F +Q++G P Sbjct: 225 KKELKAHLQMLEERKER------DHRKIGKELELFTNSQLVGAGLP 264 >3AKZ-B nrPDB Length = 487 Score = 32.9 bits (73), Expect = 0.47, Method: Composition-based stats. Identities = 44/274 (16%), Positives = 91/274 (33%), Gaps = 55/274 (20%) Query: 200 SPNIAKEMHVGHLRSTIIGESISR------LFEFAGYDVLRLNHVGDWGTQFGMLIAHLQ 253 +P+ +HVG R+ + +R + D R + ++ Q + Sbjct: 30 APSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSSR--EYEQQILESLRWCG 87 Query: 254 DKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICD 313 + + P IG Y++S +R + E+ ++ + Sbjct: 88 LDWDE----GPDIGGDFGPYRQS-ERLEIYREYAEKLVE--------------------- 121 Query: 314 VSRQELNKIYDALDVS----LIERGESFYQDRMNDIVKEFED-RGFVQVDDGRK--IVFV 366 ++ +YD D S Y+++ + + +F+ G +D K + F Sbjct: 122 -DKRAYYVVYDKEDPSKELFTTYEYPHEYKEKGHPVTIKFKVLPGKTSFEDLLKGYMEFD 180 Query: 367 PGCSIPLTIVKSDGGYTYDTSDLA-AIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM 425 I+KS+G TY+ + + R+ + D+ + Q + + Sbjct: 181 NSTLEDFIIMKSNGFPTYNFAVVVDDHLMRISH-----VFRGEDHLSNTPKQLMIY--EA 233 Query: 426 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGET 459 GW P ++LG D+ R G T Sbjct: 234 FGWEAP-----VFMHIPLILGSDRTPLSKRHGAT 262 >3H9B-A nrPDB Length = 560 Score = 32.9 bits (73), Expect = 0.50, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 21/42 (50%) Query: 192 KKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVL 233 KK++V +SP +H+GH+ I + R G++V Sbjct: 18 KKILVTCASPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVN 59 >4FU4-A nrPDB Length = 368 Score = 32.5 bits (72), Expect = 0.54, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 54/160 (33%), Gaps = 7/160 (4%) Query: 360 GRKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTI 419 G + ++ PG P T D D + + + + +I+ +H Q + Sbjct: 158 GIQSLYGPGDEDP----NPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQV 213 Query: 420 FAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKE 479 A + + P++ A + + F+ R + D+L K+ + Sbjct: 214 DAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLP 273 Query: 480 KERDKVLTAEELNAAQTSV---AYGCIKYADLSHNRLNDY 516 KE K+ A ++ +Y D +H DY Sbjct: 274 KEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDY 313 >1PEX-A nrPDB Length = 207 Score = 32.5 bits (72), Expect = 0.61, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 52/156 (33%), Gaps = 7/156 (4%) Query: 364 VFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAA 423 ++ PG P T D D + + + + +I+ +H Q + A Sbjct: 1 LYGPGDEDP----NPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAEL 56 Query: 424 QMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERD 483 + + P++ A + + F+ R + D+L K+ + KE Sbjct: 57 FLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVK 116 Query: 484 KVLTAEELNAAQTSV---AYGCIKYADLSHNRLNDY 516 K+ A ++ +Y D +H DY Sbjct: 117 KISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDY 152 >5UCZ-A nrPDB Length = 307 Score = 32.1 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 26/161 (16%), Positives = 55/161 (34%), Gaps = 18/161 (11%) Query: 369 CSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQMIGW 428 + PL I S+G Y D+A ++ E+ I + F++ A + Sbjct: 40 ENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYPHIPVALHLDHGTTFESCEKAVK--AG 97 Query: 429 YDPKVTRVFHAGFGVVLGEDKK--KFKTRSGETV--------RLMDLLGEGLKRSMDKLK 478 + + H F L K K +G +V + D + K ++ + Sbjct: 98 FTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDAKDAV-LVN 156 Query: 479 EKERDKVLTAEELNAAQTSVAY--GCIKYADLSHNRLNDYI 517 KE ++ + +++ ++ G K+ D+ Sbjct: 157 PKEAEQFVKESQVDYLAPAIGTSHGAFKF---KGEPKLDFE 194 >3AL0-C nrPDB Length = 592 Score = 32.1 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 44/274 (16%), Positives = 91/274 (33%), Gaps = 55/274 (20%) Query: 200 SPNIAKEMHVGHLRSTIIGESISR------LFEFAGYDVLRLNHVGDWGTQFGMLIAHLQ 253 +P+ +HVG R+ + +R + D R + ++ Q + Sbjct: 135 APSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSSR--EYEQQILESLRWCG 192 Query: 254 DKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLICD 313 + + P IG Y++S +R + E+ ++ + Sbjct: 193 LDWDE----GPDIGGDFGPYRQS-ERLEIYREYAEKLVE--------------------- 226 Query: 314 VSRQELNKIYDALDVS----LIERGESFYQDRMNDIVKEFED-RGFVQVDDGRK--IVFV 366 ++ +YD D S Y+++ + + +F+ G +D K + F Sbjct: 227 -DKRAYYVVYDKEDPSKELFTTYEYPHEYKEKGHPVTIKFKVLPGKTSFEDLLKGYMEFD 285 Query: 367 PGCSIPLTIVKSDGGYTYDTSDLA-AIKQRLFEEKADMIIYVVDNGQSVHFQTIFAAAQM 425 I+KS+G TY+ + + R+ + D+ + Q + + Sbjct: 286 NSTLEDFIIMKSNGFPTYNFAVVVDDHLMRISH-----VFRGEDHLSNTPKQLMIY--EA 338 Query: 426 IGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGET 459 GW P ++LG D+ R G T Sbjct: 339 FGWEAP-----VFMHIPLILGSDRTPLSKRHGAT 367 >4MB8-A nrPDB Length = 304 Score = 32.1 bits (71), Expect = 0.87, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 38/108 (35%), Gaps = 21/108 (19%) Query: 271 VFYKESKKRFDTEEEFKKRAYQCVVLL-----QGKNPDITKAWKLICDVSRQELNKIYDA 325 F K +F T E K R + V QG++ D W + D+ ++ YD Sbjct: 169 GFEGFIKDQFTTLPEVKDRCFATQVYCKWRYHQGRDVDFEATWDTVRDIVLKKFAGPYD- 227 Query: 326 LDVSLIERGESFYQDRMNDIVKEFEDRGFVQVDDGRKIVFVPGCSIPL 373 +GE Y + + + +QV ++ + I L Sbjct: 228 -------KGE--YSPSVQKTLYD------IQVLSLSRVPEIEDMEISL 260 >1IRX-A nrPDB Length = 523 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 43/292 (14%), Positives = 97/292 (33%), Gaps = 26/292 (8%) Query: 189 GENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGML 248 GE +K +V+ S + +HVG+ R + GY+V ++ D+ F + Sbjct: 17 GEKEKYVVE-SGITPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHIHMWDDYDR-FRKV 74 Query: 249 IAHLQDKFPDYLTVSPPIGDL-------QVFYKESKKRFDTEEEFKKRAYQCVVLLQGKN 301 ++ ++ DYL PI ++ + + + ++F+ E E + V LL Sbjct: 75 PRNVPQEWKDYL--GMPISEVPDPWGCHESYAEHFMRKFEEEVE---KLGIEVDLLYASE 129 Query: 302 PDITKAWKLICDVSRQELNKIYDALD----VSLIERGESFYQDRMNDIVKEFEDRGFVQV 357 + ++ ++ +KI + L+ ++ + M + + ++ Sbjct: 130 LYKRGEYSEEIRLAFEKRDKIMEILNKYREIAKQPPLPENWWPAMVYCPEHRREAEIIEW 189 Query: 358 DDGRKIVF-VPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHF 416 D G K+ + P ++S D + + + + Sbjct: 190 DGGWKVKYKCPEGHEGWVDIRSGNVKLRWRVD-----WPMRWSHFG-VDFEPAGKDHLVA 243 Query: 417 QTIFAAAQMIGWYDPKVTRVFHAGFGVV-LGEDKKKFKTRSGETVRLMDLLG 467 + + + I + V + K K G + L DL Sbjct: 244 GSSYDTGKEIIKEVYGKEAPLSLMYEFVGIKGQKGKMSGSKGNVILLSDLYE 295 >6I3O-A nrPDB Length = 677 Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 33/211 (15%), Positives = 67/211 (31%), Gaps = 34/211 (16%) Query: 454 TRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQTSVAYG-------CIKYA 506 T SG+T ++ L E + + +V V I++ Sbjct: 37 TGSGKTTQVTQYLAEAGFTKYGMIGCTQPRRVAAVSVAKRVAEEVGCQLGQEVGYTIRFE 96 Query: 507 DLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILL 566 D+ + + D ML R +D ++ R + I+L Sbjct: 97 DV-TSPATKIKYMTDGMLQ--------------------REILMDPDL----KRYSVIML 131 Query: 567 DHEKEWKLGRCILRFPEILQKILDDLFLHTLCDYIYELATAFTEFYDSCYCVEKDRQTGK 626 D E + +L F + + + L + A F+E+++SC +T Sbjct: 132 DEAHERTIATDVL-FALLKKTVKRRPDLKVIVTSATLDAEKFSEYFNSCPIFTIPGRTFP 190 Query: 627 ILKVNMWRMLLCEAVAAVMAKGFDILGIKPV 657 + ++ R + + A + I +P Sbjct: 191 V-EILYSREPEPDYLEAALTTVMQIHLTEPP 220 >6BRL-A nrPDB Length = 511 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 44/290 (15%), Positives = 96/290 (33%), Gaps = 40/290 (13%) Query: 192 KKVIVDFSSPNIAKEMHVGHLRSTII---------GESISRLFEFAGYDVLRLNHVGDWG 242 +KV V F +P+ +H+G +R+ + G+ I R+ D +V Sbjct: 10 EKVRVRF-APSPTGPLHLGGVRTALYDYLFAKHNGGDFILRI-----EDTDTQRYVPGSE 63 Query: 243 TQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNP 302 + + + P Y++S++R + ++ L P Sbjct: 64 EYIMEALEWIGMVPDESPKHGGPYAP----YRQSERRDIYDRYTEQILKTDYAYLAFDTP 119 Query: 303 DITKAWKLICDVSRQELNKIYDALD-----VSLIERGESFYQDRMNDIVKEFED--RGFV 355 + + + Y+ + +SL E + V F+ + Sbjct: 120 EELDQIRAEFEARGDVFAYNYETRNRLRNSISLPEEEVKKLLEEKTPYVIRFKMPLDRII 179 Query: 356 QVDDGRKIVFVPGCS--IPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQS 413 ++D + F + +VK+DG TY +++ ++ I +V+ + Sbjct: 180 NLNDIIRGKFSVNTNTLDDKVLVKNDGMPTYHFANII-------DDHEMKITHVIRGEEW 232 Query: 414 VHFQTIFAAA-QMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRL 462 + + + +GW P+ H ++ E K K R G+ Sbjct: 233 LPSMALHVLLYEAMGWDAPEFA---HLSL-ILKPEGKGKLSKRDGDKFGF 278 >5W1A-A nrPDB Length = 810 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 32/77 (41%), Gaps = 6/77 (7%) Query: 129 EQKVNPREIAENITKHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLPAL 188 E K A + L N +E + I GF N + DF ++ ++N + + Sbjct: 678 EMKQPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDF---KMRYQILNPKGIKGI 734 Query: 189 GENK---KVIVDFSSPN 202 + K KV+++ + N Sbjct: 735 EDPKKCTKVLIESTELN 751 >5BNZ-A nrPDB Length = 564 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 30/62 (48%), Gaps = 10/62 (16%) Query: 168 KDFVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEF 227 +F+ + + + L G++ K++ F P +H+GH +S + +++ EF Sbjct: 18 PNFLRQIVQADL-------DAGKHAKIVTRF-PPEPNGYLHIGHAKSICLNFGLAQ--EF 67 Query: 228 AG 229 AG Sbjct: 68 AG 69 >5E9F-A nrPDB Length = 560 Score = 30.9 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 40/131 (30%), Gaps = 19/131 (14%) Query: 249 IAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFK-------KRAYQCVVLLQGKN 301 ++ K PDY + Y E K ++ F + L G Sbjct: 401 AIWMESKLPDYEQAKEFAEGVHAVYPEQKLAYNLSPSFNWKTAMPRDEQETYIRRLAGLG 460 Query: 302 PDITKAWKLICDVSRQELNKIYDALDVSLIER-----GESFYQDRMN---DIVKEFEDRG 353 W+ I I D + E GE + M D+VK + G Sbjct: 461 Y----CWQFITLAGLHTTALISDRFARAYSEVGMRAYGELVQEPEMELGVDVVKHQKWSG 516 Query: 354 FVQVDDGRKIV 364 VD+ +K+V Sbjct: 517 ATYVDELQKMV 527 >4G6Z-A nrPDB Length = 490 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 36/277 (12%), Positives = 79/277 (28%), Gaps = 56/277 (20%) Query: 200 SPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFPDY 259 +P+ +H+G++RS + + +R + G + ++D + Sbjct: 31 APSPTGFIHLGNIRSALYPWAFARKMK-------------------GTFVLRIEDTDVER 71 Query: 260 LTVSPPIGDLQVFYKESKKRFDTEEEFK----KRAYQCVVLLQGKNPDITKAWKLICDVS 315 + L+ +D ++ R + + +Q K C +S Sbjct: 72 SSQEAVDAILEGMAWLGLD-YDEGPYYQMQRMDRYREVLAQMQEKGLVY------PCYMS 124 Query: 316 RQELNKIYD---------ALDVSLIERGESFYQDRMNDIVKEFEDRG-----FVQVDDGR 361 +EL+ + + D + + + R D + Sbjct: 125 TEELDALRERQRAAGEKPRYDGTWRPEPGKVLPEPPAGVAPVLRFRNPLTGTVAWDDAVK 184 Query: 362 KIVFVPGCS-IPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQTIF 420 V + L + + DG Y+ + +I D+ + Q Sbjct: 185 GRVEISNEELDDLVVARPDGTPMYNFCVVVDDLDMGITH----VIRGDDHVNNTPRQ--I 238 Query: 421 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSG 457 + +G P + VL E +K R G Sbjct: 239 NILRALGGEVPVYAHL-----PTVLNEQGEKMSKRHG 270 >4ZTY-A nrPDB Length = 769 Score = 30.9 bits (68), Expect = 1.8, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 36/111 (32%), Gaps = 3/111 (2%) Query: 244 QFGMLIAHLQDKFPDYLTVSPPIGDL-QVFYKESK--KRFDTEEEFKKRAYQCVVLLQGK 300 Q L L+D+ D + + + +E ++ E + K A L Sbjct: 583 QCQQLALALRDEVVDLEKNGIYVIQVDEPALREGLPLRKGQEREAYLKWAVDSFKLATAG 642 Query: 301 NPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFED 351 + T+ C Q+ ALD ++ S ++ + + E Sbjct: 643 VENSTQIHSHFCYSEFQDFFHAIAALDADVLSIENSKSDAKLLKVFIDEEY 693 >1QU3-A nrPDB Length = 917 Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 191 NKKVIVDFSSPNIAKEMHVGHLRSTIIGESISR 223 N+ I+ P +H+GH + I+ + I R Sbjct: 47 NETFILHDGPPYANGNLHMGHALNKILKDFIVR 79 >2JJ9-A nrPDB Length = 788 Score = 30.6 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 24/77 (31%), Gaps = 1/77 (1%) Query: 128 KEQKVNPREIAENIT-KHLPDNECIEKVEIAGPGFINVHLRKDFVSEQLTSLLVNGVQLP 186 K P ++ + + L N +E + I GF N + DFV Sbjct: 669 PNNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAE 728 Query: 187 ALGENKKVIVDFSSPNI 203 + ++ + + Sbjct: 729 DSQKATDAVLKHLNIDP 745 >2DHR-A nrPDB Length = 499 Score = 30.6 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 20/174 (11%), Positives = 57/174 (32%), Gaps = 22/174 (12%) Query: 408 VDNGQSVHFQTIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLG 467 +++ VH TI + +G+ P+ + H +L + R+ E + D+ Sbjct: 304 LEHADGVHKVTIVPRGRALGFMMPRREDMLHWSRKRLLDQIAVALAGRAAEEIVFDDVTT 363 Query: 468 -------EGLKRSMDKLKEKERDKVLTAEELNAAQTSV--AYGCIKYADLSHNRLNDYIF 518 + + + + E + + Y +Y++ + R+++ + Sbjct: 364 GAENDFRQATELARRMITEWGMHPEFGPVAYAVREDTYLGGYDVRQYSEETAKRIDEAVR 423 Query: 519 SFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEW 572 + + R++++ E + + E + L E + Sbjct: 424 RL-------------IEEQYQRVKALLLEKREVLERVAETLLERETLTAEEFQR 464 >5ZDO-A nrPDB Length = 548 Score = 30.6 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 170 FVSEQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTII 217 F++E + L G+ K++ F P +H+GH RS ++ Sbjct: 8 FITELVERDL-------KEGKYAKLVTRF-PPEPNGYLHIGHARSIVL 47 >5L3R-A nrPDB Length = 301 Score = 30.2 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 36/102 (35%), Gaps = 6/102 (5%) Query: 440 GFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKLKEKERDKVLTAEELNAAQT-SV 498 FG + G + + GE V D + E ++ L E + + + + +V Sbjct: 7 MFGQLTGGLEAAWSKLKGEEVLTKDNIAEPMRDIRRALLEADVSLPVVRRFVQSVSDQAV 66 Query: 499 AYGCIKYADLSHNRLNDYI-FSFDKMLDDRGNTAAYLLYAFT 539 G I+ + D+++ G + L +A + Sbjct: 67 GMGVIR----GVKPDQQLVKIVHDELVKLMGGEVSELQFAKS 104 >2D54-A nrPDB Length = 502 Score = 30.2 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 19/40 (47%) Query: 203 IAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWG 242 + E H+GH +T++ + ++R GY L + G Sbjct: 14 VNAEPHLGHAYTTVVADFLARWHRLDGYRTFFLTGTDEHG 53 >5I4E-A nrPDB Length = 980 Score = 30.2 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 52/149 (34%), Gaps = 12/149 (8%) Query: 141 ITKHLPDNECIEKVEIAGPGFINVHLRKDF---VSEQLTSLLVNGVQLPALGENKKVIVD 197 + L N +E + I GF N L ++F + + G K + Sbjct: 666 VLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQAL 725 Query: 198 FSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGMLIAHLQDKFP 257 PN+ + VG + +++L E + + +++ + L+ + DK Sbjct: 726 ELDPNLYR---VGQSKIFFRAGVLAQLEEERASEQTKSDYL----KRANELVQWINDKQA 778 Query: 258 --DYLTVSPPIGDLQVFYKESKKRFDTEE 284 + I +Q F K+ TE+ Sbjct: 779 SLESRDFGDSIESVQSFMNAHKEYKKTEK 807 >4P2B-A nrPDB Length = 576 Score = 29.8 bits (65), Expect = 3.5, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 60/181 (33%), Gaps = 41/181 (22%) Query: 183 VQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDVLRLN------ 236 + G++K VI F P +H+GH +S + +++ F G LR + Sbjct: 30 EEDLRTGKHKTVITRF-PPEPNGFLHLGHAKSVCLNFGLAK--AFGGRCHLRFDDTNPMK 86 Query: 237 ----HV-----------GDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFD 281 ++ GDWG + D F + ++ K+ D Sbjct: 87 EETRYIESIQRDVRWLGGDWGNHLY----YASDYFQQLYDWA------ELLIKKGLAFVD 136 Query: 282 TEEEFKKRAYQCVVLLQGKNPDITKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDR 341 + + R + + G+N + S +E ++ + E G + + Sbjct: 137 DDSLEEIRRKRGSISQPGEN-------SPFRERSIEENLDLFRRMRAGEFEEGSRVLRAK 189 Query: 342 M 342 + Sbjct: 190 I 190 >2CV2-A nrPDB Length = 468 Score = 29.4 bits (64), Expect = 5.2, Method: Composition-based stats. Identities = 73/422 (17%), Positives = 146/422 (34%), Gaps = 65/422 (15%) Query: 194 VIVDFSSPNIAKEMHVGHLRSTII---------GESISRLFEFAGYDVLRLNHVGDWGTQ 244 ++V +P+ + HVG + G I R+ D R +V + Sbjct: 1 MVVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRI-----EDTDRARYVPGAEER 55 Query: 245 FGMLIAHLQDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDI 304 + L + + P +G Y++S +R +++ + +L +G Sbjct: 56 ILAALKWLGLSYDE----GPDVGGPHGPYRQS-ERLPLYQKYAEE-----LLKRGWAYRA 105 Query: 305 TKAWKLICDVSRQELNKIYDALDVSLIERGESFYQDRMNDIVKEFEDRGFVQV-DDGRKI 363 + + + + +++ A ++ E E + + I + G +V D+ R + Sbjct: 106 FETPEELEQIRKEKGGYDGRARNIPPEEAEERARRGEPHVIRLKVPRPGTTEVKDELRGV 165 Query: 364 VFVPGCSIP-LTIVKSDGGYTYDTSDLA--AIKQRLFEEKADMIIYVVDNGQSVHFQTIF 420 V IP + ++KSDG TY +++ + +A+ ++V V F Sbjct: 166 VVYDNQEIPDVVLLKSDGYPTYHLANVVDDHLMGVTDVIRAEE--WLVSTPIHVLLYRAF 223 Query: 421 AAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSG----ETVRLMDLLGEGLKRSMDK 476 GW P R +H ++ DK K R + + L E L+ + Sbjct: 224 ------GWEAP---RFYHM--PLLRNPDKTKISKRKSHTSLDWYKAEGFLPEALRNYLCL 272 Query: 477 LKEKERD--KVLTAEELNAA--QTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAA 532 + D ++ T EE A V+ G DL R + + ++L Sbjct: 273 MGFSMPDGREIFTLEEFIQAFTWERVSLGG-PVFDLEKLRWMNGKY-IREVLSLEE---- 326 Query: 533 YLLYAFTRIRSIARLANIDEEMLQKAARETKILLDHEKEWKLGRCILRFPEILQKILDDL 592 R++ R A + E +A + L + L FPE + + + Sbjct: 327 ----VAERVKPFLREAGLSWE--SEAYLRRAVELMRPRFDTLK----EFPEKARYLFTED 376 Query: 593 FL 594 + Sbjct: 377 YP 378 >4MWD-A nrPDB Length = 542 Score = 29.4 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 18/40 (45%) Query: 208 HVGHLRSTIIGESISRLFEFAGYDVLRLNHVGDWGTQFGM 247 H+GH+ ST+I + I R G V L + G + Sbjct: 25 HIGHVYSTLITDVIGRYHRVKGERVFALTGTDEHGQKVAE 64 >2ZKT-A nrPDB Length = 412 Score = 29.0 bits (63), Expect = 6.2, Method: Composition-based stats. Identities = 22/162 (13%), Positives = 54/162 (33%), Gaps = 10/162 (6%) Query: 358 DDGRKIVFVPGCSIPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSVHFQ 417 DD V + + G +++ A R +E+ D+ + + G + H Sbjct: 94 DDLAFRVNFATLENGIITDRRAGR---ISTEEAHELARAIQEEVDIGVDFIFKGATGHRA 150 Query: 418 TIFAAAQMIGWYDPKVTRVFHAGFGVVLGEDKKKFKTRSGETVRLMDLLGEGLKRSMDKL 477 + G+ G+ KF ++ ++ ++L E +K++ + L Sbjct: 151 VLVLKGMSRGYKVGDNDPHEA-------GKPPLKFSYEDEDSKKVAEILEEFVKKAQEVL 203 Query: 478 KEKERDKVLTAEELNAAQTSVAYGCIKYADLSHNRLNDYIFS 519 ++ ++ E A + G Y ++ + Sbjct: 204 EKHPINERRRKEGKPIANYLLIRGAGTYPNIPMKFTEQWKVK 245 >5UMD-R nrPDB Length = 294 Score = 28.6 bits (62), Expect = 8.8, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 26/71 (36%) Query: 253 QDKFPDYLTVSPPIGDLQVFYKESKKRFDTEEEFKKRAYQCVVLLQGKNPDITKAWKLIC 312 + F DYL + D++ Y + ++ E + + + V K+ K + Sbjct: 219 KTHFNDYLKNNIGADDIEQMYLNAHEKIRQNPEKESKDTKNVKKFVSKHEKPKKLNAKLR 278 Query: 313 DVSRQELNKIY 323 +E +Y Sbjct: 279 KKRVKEKLALY 289 >3EJB-B nrPDB Length = 404 Score = 28.6 bits (62), Expect = 9.1, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 2/63 (3%) Query: 173 EQLTSLLVNGVQLPALGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESISRLFEFAGYDV 232 EQ+ LL + P++ N V SPN + GH +G S++RL + Sbjct: 303 EQVYLLLGAANRDPSIFTNPDVFDITRSPNP--HLSFGHGHHVCLGSSLARLEAQIAINT 360 Query: 233 LRL 235 L Sbjct: 361 LLQ 363 >2GH9-A nrPDB Length = 386 Score = 28.6 bits (62), Expect = 9.6, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 24/71 (33%), Gaps = 2/71 (2%) Query: 118 AMGISQMLKTKEQKVNPREIAENIT--KHLPDNECIEKVEIAGPGFINVHLRKDFVSEQL 175 A ++ + K K PR E + + L + G + N K F +E + Sbjct: 112 AESVALIYNKKYVKEPPRTWEEFLALAQKLTTGATFGFLYNIGDPYFNFGFFKAFGAENV 171 Query: 176 TSLLVNGVQLP 186 + G P Sbjct: 172 FAKDAKGNLDP 182 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.122 0.289 Lambda K H 0.267 0.0376 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,575,330 Number of Sequences: 36641 Number of extensions: 747758 Number of successful extensions: 2649 Number of sequences better than 10.0: 63 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 2478 Number of HSP's gapped (non-prelim): 117 length of query: 660 length of database: 10,336,785 effective HSP length: 103 effective length of query: 557 effective length of database: 6,562,762 effective search space: 3655458434 effective search space used: 3655458434 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 62 (28.6 bits)