BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P53780 (464 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1IBJ-A nrPDB 958 0.0 4L0O-H nrPDB 335 3e-92 4IYO-A nrPDB 307 5e-84 5TSU-A nrPDB 305 3e-83 6CJB-A nrPDB 293 8e-80 3MKJ-A nrPDB 293 1e-79 5DX5-A nrPDB 281 4e-76 1E5F-A nrPDB 280 1e-75 3AEO-A nrPDB 279 2e-75 1N8P-A nrPDB 279 2e-75 5X5H-A nrPDB 278 4e-75 3QI6-A nrPDB 278 5e-75 1CS1-A nrPDB 263 1e-70 3VK2-A nrPDB 254 4e-68 4U1T-A nrPDB 254 5e-68 1PFF-A nrPDB 246 2e-65 1I43-A nrPDB 223 1e-58 3NDN-A nrPDB 215 4e-56 4KAM-A nrPDB 200 8e-52 5IJG-A nrPDB 200 9e-52 4OC9-A nrPDB 191 6e-49 2CTZ-A nrPDB 172 4e-43 3RI6-A nrPDB 164 5e-41 2CB1-A nrPDB 160 1e-39 2FQ6-A nrPDB 148 6e-36 1U08-A nrPDB 42 8e-04 5XT5-A nrPDB 38 0.008 3JUL-A nrPDB 37 0.018 4W91-A nrPDB 37 0.023 3CAI-A nrPDB 35 0.096 2AEV-A nrPDB 34 0.16 5OLJ-A nrPDB 33 0.34 1J32-A nrPDB 33 0.36 6HRH-B nrPDB 32 0.42 4AC8-A nrPDB 32 0.46 4Q75-A nrPDB 32 0.47 5TXT-B nrPDB 32 0.56 1T3I-A nrPDB 32 0.60 4LHD-A nrPDB 31 0.88 6F35-A nrPDB 31 1.1 2CKS-A nrPDB 31 1.1 6C9E-A nrPDB 30 2.6 3FFH-A nrPDB 30 3.1 4BMK-A nrPDB 29 4.0 2XPY-A nrPDB 29 4.1 4UX8-A nrPDB 28 7.4 >1IBJ-A nrPDB Length = 464 Score = 958 bits (2476), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/464 (100%), Positives = 464/464 (100%) Query: 1 MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKS 60 MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKS Sbjct: 1 MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKS 60 Query: 61 VDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI 120 VDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI Sbjct: 61 VDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI 120 Query: 121 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV 180 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV Sbjct: 121 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV 180 Query: 181 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS 240 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS Sbjct: 181 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS 240 Query: 241 EMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK 300 EMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK Sbjct: 241 EMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK 300 Query: 301 EVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGL 360 EVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGL Sbjct: 301 EVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGL 360 Query: 361 PDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420 PDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS Sbjct: 361 PDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420 Query: 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL 464 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL Sbjct: 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL 464 >4L0O-H nrPDB Length = 388 Score = 335 bits (859), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 159/362 (43%), Positives = 237/362 (65%) Query: 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALS 162 A+S P+YQT+T++Q + + Y+Y+RSGNPTR ALE L+A L+ + F F SG+A + Sbjct: 20 AVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIH 79 Query: 163 AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVW 222 AV L+++G+ ++ GDDVYGG+ RL +QV+ ++G+ ++T+ + ++ AI P TK ++ Sbjct: 80 AVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIIDTSDISQIKKAIKPNTKALY 139 Query: 223 LESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAG 282 LE+P+NP +I+D+ + + +A G L +VDN+ +P PL LGADIV HS TK++ G Sbjct: 140 LETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFATPYYQNPLLLGADIVAHSGTKYLGG 199 Query: 283 HSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKI 342 HSDV+AG++ E LA+E+ F QN+ G L P D WL RGIKT+ LR+E Q+NA + Sbjct: 200 HSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCV 259 Query: 343 AMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSI 402 A +L HP+V++VYY GLP HP + L Q +G + SF + + + VE+ K F + Sbjct: 260 AEFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFIL 319 Query: 403 AVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTF 462 S G V+SL+ +P FM+HA IP REA G+ + LVR+S GIE DL+ DL+ AF Sbjct: 320 GESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKI 379 Query: 463 PL 464 L Sbjct: 380 GL 381 >4IYO-A nrPDB Length = 397 Score = 307 bits (787), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 168/379 (44%), Positives = 238/379 (62%), Gaps = 6/379 (1%) Query: 86 SVSTLLVNLDNKFDP-FDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAK 144 S++TL ++ DP A+ P+Y T+T+ Q S E+ ++Y+R+ NPTR A E +A Sbjct: 16 SLATLAIHGGQSPDPSTGAVMPPIYATSTYAQSSPGEHQGFEYSRTHNPTRFAYERCVAA 75 Query: 145 LDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRS-GVVVKRVN 203 L+ RAF F SGMAA S V L+ G +VA DD+YGG+ RL +V R+ G+ V+ Sbjct: 76 LEGGTRAFAFASGMAATSTVMELLDAGSHVVAMDDLYGGTFRLFERVRRRTAGLDFSFVD 135 Query: 204 TTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSR 263 T AAI TK+VW+E+PTNP ++ DI I+ +A G L +VDN+ SP+L R Sbjct: 136 LTDPAAFKAAIRADTKMVWIETPTNPMLKLVDIAAIAVIARKHGLLTVVDNTFASPMLQR 195 Query: 264 PLELGADIVMHSATKFIAGHSDVMAGVLAVKGE--KLAKEVYFLQNSEGSGLAPFDCWLC 321 PL LGAD+V+HSATK++ GHSD++ G+ AV G+ +LA+++ FLQNS G PFD +L Sbjct: 196 PLSLGADLVVHSATKYLNGHSDMVGGI-AVVGDNAELAEQMAFLQNSIGGVQGPFDSFLA 254 Query: 322 LRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFS 381 LRG+KT+ LR+ ENA +A +L +HP ++KV Y GL HP H L Q G G + S Sbjct: 255 LRGLKTLPLRMRAHCENALALAQWLETHPAIEKVIYPGLASHPQHVLAKRQMSGFGGIVS 314 Query: 382 FI-TGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVR 440 + G +K E T+ F++A S G V+SL++ P M+HASIP RE G+++ LVR Sbjct: 315 IVLKGGFDAAKRFCEKTELFTLAESLGGVESLVNHPAVMTHASIPVARREQLGISDALVR 374 Query: 441 ISAGIEDVDDLISDLDIAF 459 +S GIED+ DL DL+ A Sbjct: 375 LSVGIEDLGDLRGDLERAL 393 >5TSU-A nrPDB Length = 422 Score = 305 bits (781), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 149/344 (43%), Positives = 223/344 (64%), Gaps = 2/344 (0%) Query: 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALS 162 A+ P+ + TFKQ + ++ ++Y+RSGNPTR+ LE +A LD A F SG+AA Sbjct: 53 AVVPPISLSTTFKQGAPGQHSGFNYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATV 112 Query: 163 AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVW 222 +THL+K G++I+ DDVYGG++ QV G+ + V+ +K+ + AAI P+TKLVW Sbjct: 113 TITHLLKAGDQIICMDDVYGGTNLYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVW 172 Query: 223 LESPTNPRQQISDIRKISEMAHAQGALVLV-DNSIMSPVLSRPLELGADIVMHSATKFIA 281 +E+PTNP Q++ DI + + H G ++LV DN+ MSP RPL LGADI M+SATK++ Sbjct: 173 IETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMN 232 Query: 282 GHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARK 341 GHSDV+ G+++V E L + FLQNS G+ +P DC+LC RG+KT+ +R+EK +N Sbjct: 233 GHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMA 292 Query: 342 IAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGA-GSVFSFITGSVALSKHLVETTKYF 400 +A +L S+P V+KV Y GLP HP H L Q G G V +I G++ ++ ++ K F Sbjct: 293 VAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLF 352 Query: 401 SIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAG 444 ++AVS G +SL +P M+HAS+ R+ G+++ L+R+S G Sbjct: 353 TLAVSLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 396 >6CJB-A nrPDB Length = 391 Score = 293 bits (751), Expect = 8e-80, Method: Compositional matrix adjust. Identities = 153/360 (42%), Positives = 238/360 (66%), Gaps = 3/360 (0%) Query: 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALS 162 A+ TP+Y T+T+KQ + E+ Y+Y+R+ NPTR A E +A L+ + F F SGMAA++ Sbjct: 31 AVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIASLESGQKGFAFASGMAAIN 90 Query: 163 AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPR-SGVVVKRVNTTKLDEVAAAIGPQTKLV 221 V L+ +G+ +VA DD+YGG+ RL +V R S + ++ + + + AAI P+TKL+ Sbjct: 91 TVIDLLGSGDHVVAMDDLYGGTFRLFDKVKTRTSNLSFSFIDMSVPENIEAAITPKTKLL 150 Query: 222 WLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIA 281 WLE+P+NP +++++RKI+ +A + + DN+ +P + RPLELG DIV+HSATK++ Sbjct: 151 WLETPSNPMLKLANLRKIAAIAKKYNLITVADNTFATPWIQRPLELGFDIVLHSATKYLN 210 Query: 282 GHSDVMAGVLAVKGEK-LAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENAR 340 GHSDV++GV+ V L+ ++ FLQNS G+ PFD +L LR +KT+++R+++ ENA Sbjct: 211 GHSDVVSGVVVVGDNSVLSDKIAFLQNSCGAVAGPFDSFLVLRSLKTLSVRMQRHCENAN 270 Query: 341 KIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFI-TGSVALSKHLVETTKY 399 +A +LSSHP+++KV Y GL HP + L Q G + S + GS+ +K + + Sbjct: 271 HLANWLSSHPKIEKVIYPGLKSHPQYSLAKEQMNNFGGMISLVLKGSLEDAKRFLARCEL 330 Query: 400 FSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 F++A S G V+SLI P M+HASIP E R+A G+ + +R+S GIE +DDL +DL+ A Sbjct: 331 FTLAESLGGVESLIEHPAIMTHASIPVEQRKALGIEDGFIRLSVGIEHIDDLRADLEHAL 390 >3MKJ-A nrPDB Length = 398 Score = 293 bits (750), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 151/385 (39%), Positives = 239/385 (62%), Gaps = 12/385 (3%) Query: 88 STLLVNLDNKFDP-FDAMSTPLYQTATFKQPSA--------IENGPYDYTRSGNPTRDAL 138 +T +V+ + DP A+STP++QT+TF SA +E Y YTR GNPT DAL Sbjct: 10 NTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTDAL 69 Query: 139 ESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGV 197 E LA L++ + SG++A++ + L + G+ IV+ +YG + LS +P+ G+ Sbjct: 70 EKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLSHSMPKFGI 129 Query: 198 VVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIM 257 V V+ K +E+ AA+ P+TK+V++E+P NP + DI ++ +AH QGAL++VDN+ M Sbjct: 130 NVSFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGALLVVDNTFM 189 Query: 258 SPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYF-LQNSEGSGLAPF 316 SP +PL+LGADIV+HS TK+I GH DV+ G++ K E + + + L++ G ++PF Sbjct: 190 SPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMSPF 249 Query: 317 DCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGA 376 + WL LRG+KT+ +R+E+ ENA KIA +L HP + +VYY GL HP + L Q Sbjct: 250 NAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMSLP 309 Query: 377 GSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLT 435 G + SF I G + + ++ + + +AVS G ++LI P M+H+ + E R G+T Sbjct: 310 GGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLKAGIT 369 Query: 436 EDLVRISAGIEDVDDLISDLDIAFK 460 + L+R+S G+ED +D+I+DL+ A + Sbjct: 370 DGLIRLSVGLEDPEDIINDLEHAIR 394 >5DX5-A nrPDB Length = 400 Score = 281 bits (719), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 156/373 (41%), Positives = 233/373 (62%), Gaps = 15/373 (4%) Query: 101 FDAMSTPLYQTATFKQPSAIENG--------PYDYTRSGNPTRDALESLLAKLDKADRAF 152 F +++TP+YQT+TF SA + G Y Y+R GNPT +E+ LA L+ + A Sbjct: 24 FGSLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAV 83 Query: 153 CFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVA 211 SGM A++A + +K+G+ +VA D +YG + LL+ + R GV V V+ + LDEV Sbjct: 84 VAASGMGAIAASLWSALKSGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDVSNLDEVK 143 Query: 212 AAIGPQTKLVWLESPTNPRQQISDIRKISEMAHA--QGALVLVDNSIMSPVLSRPLELGA 269 A+ P TK+V+LE+P NP +++DIRKIS M H + V VDN+ +P + RPLELGA Sbjct: 144 NALKPNTKVVYLETPANPTLKVTDIRKISNMVHESNKECFVFVDNTFCTPYIQRPLELGA 203 Query: 270 DIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV--YFLQNSEGSGLAPFDCWLCLRGIKT 327 D+V+HSATK++ GH DV+AG AV E+ +V + +++ GS PF+ +L +RG+KT Sbjct: 204 DVVVHSATKYLNGHGDVIAG-FAVGKEEFINQVKLFGIKDMTGSVTGPFESFLIIRGMKT 262 Query: 328 MALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGS 386 + LR+EK +NA ++A +L SHP V+KVYY GL + L Q K G++ SF + G Sbjct: 263 LQLRMEKHCKNAMEVAKFLESHPAVEKVYYPGLESFKYYQLAREQMKLPGAMISFELKGG 322 Query: 387 VALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIE 446 V K ++ K ++AVS G ++LI P M+H+ AE R+A G+++ LVR+S G+E Sbjct: 323 VEEGKIVMNNVKLATLAVSLGDSETLIQHPASMTHSPYTAEERKAAGISDGLVRLSVGLE 382 Query: 447 DVDDLISDLDIAF 459 D +D+I DL A Sbjct: 383 DAEDIIDDLKQAL 395 >1E5F-A nrPDB Length = 404 Score = 280 bits (715), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 147/385 (38%), Positives = 235/385 (61%), Gaps = 12/385 (3%) Query: 83 EEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENG--------PYDYTRSGNPT 134 E + +T ++ + + D F A P+YQT+TF + + G Y YTR GNPT Sbjct: 4 ERMTPATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPT 63 Query: 135 RDALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVP 193 LE +A L+K + +SGM A++A V ++K G+ +++ + +YG + L + Sbjct: 64 VSNLEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALT 123 Query: 194 RSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ-GALVLV 252 + G+ V +NT EV + P TK+V+ E+P NP +I D+ ++ + AH+Q G LV+ Sbjct: 124 KFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHSQEGVLVIA 183 Query: 253 DNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEGS 311 DN+ SP+++ P++ G D+V+HSATK+I GH+DV+AG++ K + L + + +++ GS Sbjct: 184 DNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDITGS 243 Query: 312 GLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFS 371 ++P D WL RG+ T+ +R++ + ENA K+A YL SHP V+KVYY G DH GH + Sbjct: 244 VISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKK 303 Query: 372 QAKGAGSVFSFITGS-VALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVRE 430 Q + GS+ +FI S +K L++ K ++AVS G +SLI P M+HA +P E RE Sbjct: 304 QMRMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEERE 363 Query: 431 ARGLTEDLVRISAGIEDVDDLISDL 455 A G+T+ ++R+S GIED D+LI+D Sbjct: 364 AAGITDGMIRLSVGIEDADELIADF 388 >3AEO-A nrPDB Length = 389 Score = 279 bits (713), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 143/365 (39%), Positives = 225/365 (61%), Gaps = 9/365 (2%) Query: 107 PLYQTATF-----KQPSAIENGP---YDYTRSGNPTRDALESLLAKLDKADRAFCFTSGM 158 P++QT+TF +Q + + G + Y+R GNPT + E ++ ++ A + F SGM Sbjct: 25 PIFQTSTFCFDSTQQGADLFMGKGEGHIYSRLGNPTVEQFEEMVCSIEGAAGSAAFGSGM 84 Query: 159 AALSAVT-HLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQ 217 A+S+ T ++ G+ ++AGD +YG + L + +PR G+ V ++T+ +++V AA P Sbjct: 85 GAISSSTLAFLQKGDHLIAGDTLYGCTVSLFTHWLPRFGIEVDLIDTSDVEKVKAAWKPN 144 Query: 218 TKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSAT 277 TK+V+LESP NP ++SDI+ I+ + H +GA ++VD + SP +PLELGADI +HS + Sbjct: 145 TKMVYLESPANPTCKVSDIKGIAVVCHERGARLVVDATFTSPCFLKPLELGADIALHSVS 204 Query: 278 KFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQE 337 K+I GH DV+ GV + K + + F + GS +AP D +LC RG+KT+ +R++ E Sbjct: 205 KYINGHGDVIGGVSSAKTAEDIATIKFYRKDAGSLMAPMDAFLCARGMKTLPIRMQIHME 264 Query: 338 NARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETT 397 N K+A +L H ++ KV + GL PGH + Q G GS F F S +K L+E Sbjct: 265 NGLKVAKFLEQHEKIVKVNHPGLESFPGHDIAKKQMTGYGSTFLFEMKSFEAAKKLMEHL 324 Query: 398 KYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDI 457 K ++AVS G V +LI P M+HA++P + +G+T +LVRIS GIE+VDD+I+DL Sbjct: 325 KVCTLAVSLGCVDTLIEHPASMTHAAVPENIMRKQGITPELVRISVGIENVDDIIADLKQ 384 Query: 458 AFKTF 462 A + + Sbjct: 385 ALELW 389 >1N8P-A nrPDB Length = 393 Score = 279 bits (713), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 153/389 (39%), Positives = 229/389 (58%), Gaps = 10/389 (2%) Query: 81 IKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPS-AIENGPYDYTRSGNPTRDALE 139 ++E +T ++ D ++ P+ + TFKQ S A G Y+Y+RS NP R+ LE Sbjct: 2 LQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLE 61 Query: 140 SLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVV 199 +A L+ A F+SG A + + + G V+ DVYGG+ R ++V GV Sbjct: 62 RAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVET 121 Query: 200 KRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEM----AHAQGALVLVDNS 255 N L+++ I TKLVW+E+PTNP +++DI+K++++ A Q +++VDN+ Sbjct: 122 SFTNDL-LNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNT 180 Query: 256 IMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAP 315 +SP +S PL GADIV+HSATK+I GHSDV+ GVLA + L + + FLQN+ G+ +P Sbjct: 181 FLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSP 240 Query: 316 FDCWLCLRGIKTMALRIEKQQENARKIAMYLSS-HPRVKKVYYAGLPDHPGHHLHFSQAK 374 FD WL RG+KT+ LR+ + +A KIA +L++ V V Y GL HP + + Q + Sbjct: 241 FDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHR 300 Query: 375 GA--GSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREA 431 A G + SF I G + +T+ F++A S G ++SL+ +P M+H IP E REA Sbjct: 301 DALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREA 360 Query: 432 RGLTEDLVRISAGIEDVDDLISDLDIAFK 460 G+ +DLVRIS GIED DDL+ D+ A K Sbjct: 361 SGVFDDLVRISVGIEDTDDLLEDIKQALK 389 >5X5H-A nrPDB Length = 392 Score = 278 bits (711), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 150/368 (40%), Positives = 222/368 (60%), Gaps = 8/368 (2%) Query: 99 DPFDAMSTPLYQTATFKQ--PSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTS 156 D + +++TP+Y + TF Q P+ + G Y+YTR GNPT ALE +A L+ A F+S Sbjct: 23 DYYGSINTPIYASTTFAQNAPNELRKG-YEYTRVGNPTIVALEQTVAALEGAKYGRAFSS 81 Query: 157 GMAALSAVTHLI-KNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIG 215 GMAA + +I K G+ IV G+D YGG+ RL+ V GV V+T+ ++EV AAI Sbjct: 82 GMAATDILFRIILKPGDHIVLGNDAYGGTYRLIDTVFTAWGVEYTVVDTSVVEEVKAAIK 141 Query: 216 PQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHS 275 TKL+W+E+PTNP I+DI ++++ A ++VDN+ SP L +PL+LGA V+HS Sbjct: 142 DNTKLIWVETPTNPALGITDIEAVAKLTEGTNAKLVVDNTFASPYLQQPLKLGAHAVLHS 201 Query: 276 ATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQ 335 TK+I GHSDV+ G++ +++ +E+ F+Q G + FD +L RG+KT+A+R+++ Sbjct: 202 TTKYIGGHSDVVGGLVVTNDQEMDEELLFMQGGIGPIPSVFDAYLTARGLKTLAVRMDRH 261 Query: 336 QENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALSKHLV 394 +NA KIA +L S P V V Y GL +HPGH + Q K G + S G +K Sbjct: 262 CDNAEKIAEFLDSRPEVSTVLYPGLKNHPGHEVAAKQMKRFGGMISVRFAGGEEAAKKFC 321 Query: 395 ETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISD 454 +TK +A S G V+SL+ P M+H S E + DLVRIS GIED++DL++D Sbjct: 322 TSTKLICLAESLGGVESLLEHPATMTHQSAAGSQLE---VPRDLVRISIGIEDIEDLLAD 378 Query: 455 LDIAFKTF 462 ++ A Sbjct: 379 VEQALNNL 386 >3QI6-A nrPDB Length = 392 Score = 278 bits (710), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 160/379 (42%), Positives = 226/379 (59%), Gaps = 7/379 (1%) Query: 85 ASVSTLLVNLDNKFDPF-DAMSTPLYQTATFKQPSAIE-NGPYDYTRSGNPTRDALESLL 142 A ++T ++ + DP A++ P+Y ++TF Q G Y+Y R+GNPTR ALE+ L Sbjct: 16 AGLATRAIHSGYRPDPATGAVNAPIYASSTFAQDGVGGLRGGYEYARTGNPTRTALEAAL 75 Query: 143 AKLDKADRAFCFTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKR 201 A ++ A F+SGMAA A+ +++ G+ +V DD YGG+ RL+ +V V Sbjct: 76 AAVEDAAFGRAFSSGMAAADCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTGWNVEYTP 135 Query: 202 VNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVL 261 V LD V AAI P T+L+W+E+PTNP I+DI I+++ A VLVDN+ SP L Sbjct: 136 VALADLDAVRAAIRPTTRLIWVETPTNPLLSIADIAGIAQLGADSSAKVLVDNTFASPAL 195 Query: 262 SRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLC 321 +PL LGAD+V+HS TK+I GHSDV+ G L E+L + FLQN G+ PFD +L Sbjct: 196 QQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAGAVPGPFDAYLT 255 Query: 322 LRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFS 381 +RG+KT+ LR+++ ENA +A +L+ HP + V Y GLP HPGH + Q +G G + S Sbjct: 256 MRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAARQMRGFGGMVS 315 Query: 382 F-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVR 440 + ++ L T F +A S GSV+SLI P M+HAS E + +DLVR Sbjct: 316 VRMRAGRTAAEQLCAKTNIFILAESLGSVESLIEHPSAMTHASTAGSQLE---VPDDLVR 372 Query: 441 ISAGIEDVDDLISDLDIAF 459 +S GIEDV DL+ DL A Sbjct: 373 LSVGIEDVADLLDDLKQAL 391 >1CS1-A nrPDB Length = 386 Score = 263 bits (671), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 144/367 (39%), Positives = 218/367 (59%), Gaps = 2/367 (0%) Query: 96 NKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFT 155 N + + + P++ ++T+ E +DY+R GNPTRD ++ LA+L+ A Sbjct: 15 NDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTN 74 Query: 156 SGMAALSAVTHL-IKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAI 214 +GM+A+ VT + +K G+ +VA D YGGS RL + R V V+ + AA+ Sbjct: 75 TGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAAL 134 Query: 215 GPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMH 274 + KLV +ESP+NP ++ DI KI +A GA+ +VDN+ +SP L PL LGAD+V+H Sbjct: 135 AEKPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLH 194 Query: 275 SATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEK 334 S TK++ GHSDV+AGV+ K + E+ + N+ G FD +L LRG++T+ R+E Sbjct: 195 SCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMEL 254 Query: 335 QQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALSKHL 393 Q NA+ I YL + P VKK+Y+ LP++ GH + Q KG G++ SF + G + Sbjct: 255 AQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRF 314 Query: 394 VETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLIS 453 + F++A S G V+SLIS M+HA + E R A G++E L+RIS GIED +DLI+ Sbjct: 315 LGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIA 374 Query: 454 DLDIAFK 460 DL+ F+ Sbjct: 375 DLENGFR 381 >3VK2-A nrPDB Length = 398 Score = 254 bits (650), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 137/382 (35%), Positives = 225/382 (58%), Gaps = 16/382 (4%) Query: 94 LDNKFDPFD---AMSTPLYQTATFKQPS--------AIENGPYDYTRSGNPTRDALESLL 142 + + +DP D A+ P+YQTATF P+ A E + Y+R NPT + LE+ + Sbjct: 15 IHHGYDPQDHGGALVPPVYQTATFTFPTVEYGAACFAGEQAGHFYSRISNPTLNLLEARM 74 Query: 143 AKLDKADRAFCFTSGMAAL-SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKR 201 A L+ + SGM A+ S + L++ G+E++ G+ +YG + L + GV ++ Sbjct: 75 ASLEGGEAGLALASGMGAITSTLWTLLRPGDEVLLGNTLYGHTFAFLHHGIGEFGVKLRH 134 Query: 202 VNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVL 261 V+ L + AA+ P T++++ ESP NP ++DI ++++A GA V+VDN+ +P L Sbjct: 135 VDMADLQALEAAMTPATRVIYFESPANPNMHMADIAGVAKIARKHGATVVVDNTYCTPYL 194 Query: 262 SRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYF--LQNSEGSGLAPFDCW 319 RPLELGAD+V+HSATK+++GH D+ AG++ V + L + L++ G+ L+P D Sbjct: 195 QRPLELGADLVVHSATKYLSGHGDITAGIV-VGSQALVDRIRLQGLKDMTGAVLSPHDAA 253 Query: 320 LCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSV 379 L +RGIKT+ LR+++ NA+ +A +L+ P+V+ ++Y GL P + L Q G + Sbjct: 254 LLMRGIKTLNLRMDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLARQQMSQPGGM 313 Query: 380 FSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDL 438 +F + G + + + + FS AVS G +SL P M+H+S E R G++E L Sbjct: 314 IAFELKGGIGAGRRFMNALQLFSRAVSLGDAESLAQHPASMTHSSYTPEERAHYGISEGL 373 Query: 439 VRISAGIEDVDDLISDLDIAFK 460 VR+S G+ED+DDL++D+ A K Sbjct: 374 VRLSVGLEDIDDLLADVQQALK 395 >4U1T-A nrPDB Length = 389 Score = 254 bits (650), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 138/356 (38%), Positives = 209/356 (58%), Gaps = 8/356 (2%) Query: 107 PLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTH 166 P++ + T+++ A + Y Y R NPTR+ LE LA L++A A F+SG AA + + Sbjct: 27 PIHVSTTYER-RAQDEPRYFYGRGENPTREELEECLAGLERAPFATVFSSGQAAAATLLS 85 Query: 167 LIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIG-PQTKLVWLES 225 L++ G+ +V+ DDVY G+D L + R GV V+ + T + +AAA+ P LVW+E+ Sbjct: 86 LVRPGQCVVSTDDVYAGTDGLF-DLAARQGVRVRYADLTTPEGIAAALAEPDLALVWIET 144 Query: 226 PTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSD 285 PTNP + D+ ++S AH +GA V+VDN+ SPVL +PL LGAD+ ++S TK IAGH+D Sbjct: 145 PTNPLLTVVDVAEVSRRAHERGARVVVDNTFASPVLQQPLALGADVSLYSTTKSIAGHAD 204 Query: 286 VMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMY 345 V+ G L + L V + + G+ DC+L RG+ T++LR+ +Q AR + Sbjct: 205 VLGGALVYRDADLHAAVRAYRTTAGNVPGALDCFLVRRGLHTLSLRVHRQVATARVLVER 264 Query: 346 LSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSV--FSFITGSVALSKHLVETTKYFSIA 403 L + P V V+Y GLP+HP H + +Q G++ F ++ G ++ L++ F+ Sbjct: 265 LRASPVVGAVHYPGLPEHPQHAVVKAQMSAPGAIVSFDYLGGP---AERLLDRFTLFTCG 321 Query: 404 VSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 VS G V SL+ P M+H + AE R RG+ E L+R+S GIED DL DL A Sbjct: 322 VSLGGVHSLVECPALMTHRPLSAEARARRGIGESLIRLSVGIEDPQDLAEDLSRAL 377 >1PFF-A nrPDB Length = 331 Score = 246 bits (628), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 129/326 (39%), Positives = 201/326 (61%), Gaps = 3/326 (0%) Query: 137 ALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRS 195 ALE +AKL+ A+ SGM A++A V +K G+ +++ D +YG + L + + Sbjct: 2 ALEGKIAKLEHAEACAATASGMGAIAASVWTFLKAGDHLISDDCLYGCTHALFEHQLRKF 61 Query: 196 GVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ-GALVLVDN 254 GV V ++ + + P T++V+ E+P NP ++ DI + A Q LV+VDN Sbjct: 62 GVEVDFIDMAVPGNIEKHLKPNTRIVYFETPANPTLKVIDIEDAVKQARKQKDILVIVDN 121 Query: 255 SIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEGSGL 313 + SP+L+ PL+LG DIV+HSATK+I GH+DV+AG++ + + +AK + +++ G+ + Sbjct: 122 TFASPILTNPLDLGVDIVVHSATKYINGHTDVVAGLVCSRADIIAKVKSQGIKDITGAII 181 Query: 314 APFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQA 373 +P D WL RG T+ +R+++ ENA+K+A +L H VKKVYY GLPDHPGH + Q Sbjct: 182 SPHDAWLITRGTLTLDMRVKRAAENAQKVAEFLHEHKAVKKVYYPGLPDHPGHEIAKKQM 241 Query: 374 KGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARG 433 K GS+ +F + +K +++ S+AVS G +SLI P M+HA +P E REA G Sbjct: 242 KMFGSMIAFDVDGLEKAKKVLDNCHVVSLAVSLGGPESLIQHPASMTHAGVPKEEREAAG 301 Query: 434 LTEDLVRISAGIEDVDDLISDLDIAF 459 LT++L+R+S G E+V D+I DL A Sbjct: 302 LTDNLIRLSVGCENVQDIIDDLKQAL 327 >1I43-A nrPDB Length = 445 Score = 223 bits (569), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 125/365 (34%), Positives = 200/365 (54%), Gaps = 12/365 (3%) Query: 102 DAMSTPLYQTAT--FKQPSAI------ENGPYDYTRSGNPTRDALESLLAKLDKADRAFC 153 DA++TP+ T+ F + S + ++Y R GNPT LE ++ L+ A+ Sbjct: 75 DAITTPVVNTSAYFFNKTSELIDFKEKRRASFEYGRYGNPTTVVLEEKISALEGAESTLL 134 Query: 154 FTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAA 212 SGM A + + L+ G IV D Y + + ++P+ G+ ++ + + Sbjct: 135 MASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFIETILPKMGITATVIDPADVGALEL 194 Query: 213 AIG-PQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADI 271 A+ + L + ESPTNP + DI +S++ H +GALV +D + +P+ + L LGAD+ Sbjct: 195 ALNQKKVNLFFTESPTNPFLRCVDIELVSKLCHEKGALVCIDGTFATPLNQKALALGADL 254 Query: 272 VMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALR 331 V+HSATKF+ GH+DV+AG ++ KL E+ L + G L P +L +RG+KT+ LR Sbjct: 255 VLHSATKFLGGHNDVLAGCIS-GPLKLVSEIRNLHHILGGALNPNAAYLIIRGMKTLHLR 313 Query: 332 IEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALS 390 +++Q A ++A L +HP+V+ VYY GL HP HH+ Q G G SF + G + + Sbjct: 314 VQQQNSTALRMAEILEAHPKVRHVYYPGLQSHPEHHIAKKQMTGFGGAVSFEVDGDLLTT 373 Query: 391 KHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDD 450 V+ K IA SFG +S++ P MS+ + R G+ ++LVR S G+ED DD Sbjct: 374 AKFVDALKIPYIAPSFGGCESIVDQPAIMSYWDLSQSDRAKYGIMDNLVRFSFGVEDFDD 433 Query: 451 LISDL 455 L +D+ Sbjct: 434 LKADI 438 >3NDN-A nrPDB Length = 414 Score = 215 bits (547), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 124/359 (34%), Positives = 202/359 (56%), Gaps = 7/359 (1%) Query: 108 LYQTATFKQPS-AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAAL-SAVT 165 +Y +A + S A E Y Y+R GNPT E L ++ A AF SGMAA+ +++ Sbjct: 55 VYGSAAVAEKSFAGELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMAAVFTSLG 114 Query: 166 HLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLES 225 L+ G+ +VA ++G + S+++PR GV V+ L + A+ T+ V+ E+ Sbjct: 115 ALLGAGDRLVAARSLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFET 174 Query: 226 PTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSD 285 P+NP Q + DI ++E+AHA GA V++DN +P+L + LG D+V++S TK I G Sbjct: 175 PSNPMQSLVDIAAVTELAHAAGAKVVLDNVFATPLLQQGFPLGVDVVVYSGTKHIDGQGR 234 Query: 286 VMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMY 345 V+ G + E + V L G ++ F+ W+ L+G++T+A+R++ +A++IA + Sbjct: 235 VLGGAILGDREYIDGPVQKLMRHTGPAMSAFNAWVLLKGLETLAIRVQHSNASAQRIAEF 294 Query: 346 LSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGS---VALSK--HLVETTKYF 400 L+ HP V+ V Y LP HP + L Q G G+V +F VA + +++ + Sbjct: 295 LNGHPSVRWVRYPYLPSHPQYDLAKRQMSGGGTVVTFALDCPEDVAKQRAFEVLDKMRLI 354 Query: 401 SIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 I+ + G KSL++ P +H ++ E R A GL + +VRIS G+ED DDLI+D+D A Sbjct: 355 DISNNLGDAKSLVTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRAL 413 >4KAM-A nrPDB Length = 453 Score = 200 bits (509), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 132/400 (33%), Positives = 207/400 (51%), Gaps = 42/400 (10%) Query: 102 DAMSTPLYQTA--TFKQPS------AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFC 153 +A + P+YQT TF+ + +E YTR GNPT D +E +A L+ A Sbjct: 38 NARALPIYQTTSYTFENTAHAAALFGLEVPGNIYTRLGNPTTDVVEQRIAALEGGVAALF 97 Query: 154 FTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT-KLDEVA 211 +SG AA + A+ +L G+ IV+ +YGG+ L + + G+ V V+ LD Sbjct: 98 LSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLGIEVSFVDDPDNLDSWQ 157 Query: 212 AAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADI 271 AA+ P TK + E+ +NP+ + D ++E+AH G ++VDN+I +P L RP GADI Sbjct: 158 AAVRPNTKAFFGETISNPQIDLLDTPGVAEVAHRNGIPLIVDNTIATPYLIRPFTQGADI 217 Query: 272 VMHSATKFIAGHSDVMAGVLAVKG------------------------EKLAKEVYFLQ- 306 V+HSATK++ GH +AGV+ G +L Y L+ Sbjct: 218 VVHSATKYLGGHGAAIAGVIVDGGTFDWTQGRFPEFTTPDPSYHGVVFAELGAPAYALKA 277 Query: 307 -----NSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLP 361 GS +PF+ +L +G++T++LRIE+ NA+++A +L+ V V YAGLP Sbjct: 278 RVQLLRDLGSAASPFNAFLVAQGLETLSLRIERHVSNAQRVAEFLADREDVVTVNYAGLP 337 Query: 362 DHPGHHLHFS-QAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFM 419 P H KG G+V SF + G V K V K S + G V+SL+ P Sbjct: 338 GSPWHERAKKLSPKGTGAVLSFELAGGVEAGKAFVNALKLHSHVANIGDVRSLVIHPAST 397 Query: 420 SHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 +HA + + + G++ LVR++ GIE ++D+++DL++ F Sbjct: 398 THAQLSPAEQLSTGVSPGLVRLAVGIEGIEDILADLELGF 437 >5IJG-A nrPDB Length = 427 Score = 200 bits (509), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 130/386 (33%), Positives = 208/386 (53%), Gaps = 39/386 (10%) Query: 103 AMSTPLYQTATF------------------KQPSAIENGPYDYTRSGNPTRDALESLLAK 144 A+ P++ T+TF K+P A Y+R +P + +E LA Sbjct: 35 AVKPPVFLTSTFVFKTAEDGRDFFDFVSGRKEPPAGVGAGLVYSRFNHPNSEIVEDRLAV 94 Query: 145 LDKADRAFCFTSGMAALSAVTH-LIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVV----- 198 + A+ A F+SGM+A++ ++ G+ I+ +YGG++ LL++ GV Sbjct: 95 YEGAESAALFSSGMSAIATTLFAFVRPGDVILHSQPLYGGTETLLAKTFFNFGVEAVAFA 154 Query: 199 --VKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDI---RKISEMAHA-QGA--LV 250 V K E A A G + ++ +E+P NP I D+ R+++E A QG+ ++ Sbjct: 155 DGVHEATIEKAAEEALAKG-RVSVILIETPANPTNSIVDVAAVRRVAEKIEARQGSRPVI 213 Query: 251 LVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEK-LAKEVYFLQNSE 309 DN+++ PV +PL+ GAD+ ++S TK++ GHSD++AG AV G K + ++V L+ + Sbjct: 214 ACDNTLLGPVFQKPLDHGADLSVYSLTKYVGGHSDLIAG--AVLGAKSVVRQVKALRGAI 271 Query: 310 GSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGH--H 367 G+ L P CW+ R ++T+ LR+E+ NAR IA +L +HP+V+K++Y D Sbjct: 272 GTQLDPHSCWMLGRSLETLGLRMERADSNARAIAEFLRNHPKVEKLHYLPFADERSDIAA 331 Query: 368 LHFSQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPA 426 L Q GAGS FSF I G A + + + +AVS G +SL S P M+H+ +P Sbjct: 332 LFKRQCTGAGSTFSFDIKGGQAAAFRFLNALQILKLAVSLGGTESLASHPAAMTHSGVPV 391 Query: 427 EVREARGLTEDLVRISAGIEDVDDLI 452 +VRE G+ E +R+S GIE DDLI Sbjct: 392 DVRERIGVLESTIRLSIGIEHPDDLI 417 >4OC9-A nrPDB Length = 424 Score = 191 bits (485), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 123/432 (28%), Positives = 217/432 (50%), Gaps = 58/432 (13%) Query: 79 MNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFK-----QPSA---IENGPYDYTRS 130 MN +E TL ++ FD ++S P+YQ + Q +A ++ Y+R Sbjct: 2 MNFNKE----TLALHGAYNFDTQRSISVPIYQNTAYNFENLDQAAARFNLQELGNIYSRL 57 Query: 131 GNPTRDALESLLAKLDKADRAFCFTSGMAA-LSAVTHLIKNGEEIVAGDDVYGGSDRLLS 189 NPT D L LA ++ SGMAA A+ +L +G+ + + +YGG+ L+S Sbjct: 58 SNPTSDVLGQRLANVEGGAFGIPVASGMAACFYALINLASSGDNVAYSNKIYGGTQTLIS 117 Query: 190 QVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGAL 249 + G+ + + LD + I TK ++ ES +NP+ I+DI KI+++A + Sbjct: 118 HTLKNFGIEAREFDIDDLDSLEKVIDQNTKAIFFESLSNPQIAIADIEKINQIAKKHKIV 177 Query: 250 VLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSE 309 + DN++ +P L +P + G D+++HS +K+++G + G L ++ + L L+N++ Sbjct: 178 SICDNTVATPFLLQPFKHGVDVIVHSLSKYVSGQGTALGGAL-IERKDLND---LLKNND 233 Query: 310 -------------------------------------GSGLAPFDCWLCLRGIKTMALRI 332 G+ LAP + WL L+G++T+A+RI Sbjct: 234 RYKAFNTPDPSYHGLNLNTLDLPIFSIRVIITWLRDLGASLAPQNAWLLLQGLETLAVRI 293 Query: 333 EKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHL---HFSQAKGAGSVFSFITGSVAL 389 EK +NA K+A +L+SHP +K V Y L + H+L +F + +G + SF Sbjct: 294 EKHSQNAEKVANFLNSHPDIKGVNYPTLASNAYHNLFKKYFDKNFASG-LLSFEAKDYEH 352 Query: 390 SKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVD 449 ++ + + T+ F +A + G KSLI P +H+ + E + G+T+ +R+S G+E+ D Sbjct: 353 ARRICDKTQLFLLAANLGDSKSLIIHPASTTHSQLSEEELQKAGITKATIRLSIGLENSD 412 Query: 450 DLISDLDIAFKT 461 DLI+DL A ++ Sbjct: 413 DLIADLKQAIES 424 >2CTZ-A nrPDB Length = 421 Score = 172 bits (435), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 121/397 (30%), Positives = 193/397 (48%), Gaps = 44/397 (11%) Query: 107 PLYQTAT--FKQPS------AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGM 158 P+Y T + FK P A++ Y+R NPT D LE LA L+ A SG Sbjct: 24 PIYPTTSYVFKSPEHAANLFALKEFGNIYSRIMNPTVDVLEKRLAALEGGKAALATASGH 83 Query: 159 AA-LSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVN-TTKLDEVAAAIGP 216 AA A+T L + G+ IV+ ++YGG+ + R G+ V+ + + +E A Sbjct: 84 AAQFLALTTLAQAGDNIVSTPNLYGGTFNQFKVTLKRLGIEVRFTSREERPEEFLALTDE 143 Query: 217 QTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSI-MSPVLSRPLELGADIVMHS 275 +T+ W+ES NP I D+ +++ A +G ++VDN+ M L RPL GA +V HS Sbjct: 144 KTRAWWVESIGNPALNIPDLEALAQAAREKGVALIVDNTFGMGGYLLRPLAWGAALVTHS 203 Query: 276 ATKFIAGHSDVMAGVL---------------------AVKGEKLAK---EVYFLQNS--- 308 TK++ GH V+AG + G +L + E+ F+ + Sbjct: 204 LTKWVGGHGAVIAGAIVDGGNFPWEGGRYPLLTEPQPGYHGLRLTEAFGELAFIVKARVD 263 Query: 309 ----EGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHP 364 +G L PF+ W+ L G++T++LR E+ EN +A +L P+V V Y GLP HP Sbjct: 264 GLRDQGQALGPFEAWVVLLGMETLSLRAERHVENTLHLAHWLLEQPQVAWVNYPGLPHHP 323 Query: 365 GHHLHFSQAKG-AGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHA 422 H KG G+V +F + G +K + K S + G ++L P +H+ Sbjct: 324 HHDRAQKYFKGKPGAVLTFGLKGGYEAAKRFISRLKLISHLANVGDTRTLAIHPASTTHS 383 Query: 423 SIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 + E + G++ ++VR+S G+E V+DL ++L A Sbjct: 384 QLSPEEQAQAGVSPEMVRLSVGLEHVEDLKAELKEAL 420 >3RI6-A nrPDB Length = 430 Score = 164 bits (416), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 126/391 (32%), Positives = 200/391 (51%), Gaps = 35/391 (8%) Query: 97 KFDPFDAMSTPLYQTATFKQPSAIENGP--------YDYTRSGNPTRDALESLLAKLDKA 148 K D A+ TP+Y A F+ ++ E + Y+RS NPT + LE L L A Sbjct: 38 KRDVHGALRTPVYDNAAFEFENSDEIAQVSLGRALGHVYSRSSNPTVEDLEQRLKNLTGA 97 Query: 149 DRAFCFTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKL 207 SGMAA+S A+ L + G+ +V D ++G + L + +P G+ V+ V+ Sbjct: 98 LGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSFGIEVRFVDVMDS 157 Query: 208 DEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLEL 267 V A TKL++LE+ +NP+ Q++D+ +S++ HA+G ++VD ++ P L L Sbjct: 158 LAVEHACDETTKLLFLETISNPQLQVADLEALSKVVHAKGIPLVVDTTMTPPYLLEAKRL 217 Query: 268 GADIVMHSATKFIAGHSDVMAGVLAVKG-----------------------EKLAKEVYF 304 G DI + S+TKFI+G + GVL G K KEV+ Sbjct: 218 GVDIEVLSSTKFISGGGTSVGGVLIDHGLFEWKSLPSLAPYYAKAGPMAFLYKARKEVF- 276 Query: 305 LQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHP 364 QN G L+P + +L G++TMALRIE+ +NA+++A +L S P+VK V + LPD P Sbjct: 277 -QNL-GPSLSPHNAYLQSLGLETMALRIERSCQNAQELAHWLLSIPQVKCVNHPSLPDSP 334 Query: 365 GHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASI 424 + + Q + AGS+ +F S S ++ K A + KSLI P + +A Sbjct: 335 FYAIAKRQFRYAGSILTFELESKEASYRFMDALKLIRRATNIHDNKSLILSPYHVIYALN 394 Query: 425 PAEVREARGLTEDLVRISAGIEDVDDLISDL 455 E R ++ ++R+S GIE+++DL D+ Sbjct: 395 SHEERLKLEISPAMMRLSVGIEEIEDLKEDI 425 >2CB1-A nrPDB Length = 412 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 116/399 (29%), Positives = 189/399 (47%), Gaps = 40/399 (10%) Query: 99 DPFDAMSTPLYQTATFKQPSAIENGP--------YDYTRSGNPTRDALESLLAKLDKADR 150 DP A+ P+Y A + + +E G Y Y R +PT ALE L L+ A Sbjct: 15 DPHGAVGLPIYAVAAYGFKT-LEEGQERFATGEGYVYARQKDPTAKALEERLKALEGALE 73 Query: 151 AFCFTSGMAALSAVTHLI-KNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDE 209 A SG AA A + + G+E+VA ++G + L QV+ GV V+ V+ + Sbjct: 74 AVVLASGQAATFAALLALLRPGDEVVAAKGLFGQTIGLFGQVLSLMGVTVRYVDPEP-EA 132 Query: 210 VAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSI-MSPVLSRPLELG 268 V A+ +T+ V++E+ NP + D+ ++ +A G ++VDN+ + L RPL G Sbjct: 133 VREALSAKTRAVFVETVANPALLVPDLEALATLAEEAGVALVVDNTFGAAGALCRPLAWG 192 Query: 269 ADIVMHSATKFIAGHSDVMAG-VLAVKGEKLAKEVYFLQNSE------------------ 309 A +V+ S TK+ +GH V+ G VL+ + E FLQ Sbjct: 193 AHVVVESLTKWASGHGSVLGGAVLSRETELWRNYPQFLQPDLKGQIPWEALRARCFPERV 252 Query: 310 --------GSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLP 361 G L+PF+ +L +G++T+ALR+ + E AR +A L HP+VK + Y GLP Sbjct: 253 RTLGLSLCGMALSPFNAYLLFQGLETVALRVARMSETARFLAERLQGHPKVKALRYPGLP 312 Query: 362 DHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSH 421 + P H G + + G + + + + A + G ++L+ P +H Sbjct: 313 EDPAHRNARKYLASGGPILTLDLGDLERASRFLGAIRLLK-AANLGDARTLLVHPWTTTH 371 Query: 422 ASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFK 460 + + E R G+T LVR+S G+ED DL++ + A + Sbjct: 372 SRLKEEARLQAGVTPGLVRVSVGLEDPLDLLALFEEALE 410 >2FQ6-A nrPDB Length = 415 Score = 148 bits (373), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 97/352 (27%), Positives = 175/352 (49%), Gaps = 25/352 (7%) Query: 122 NGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALS-AVTHLIKNGEEIVAGDDV 180 NG Y R G T +L+ + +L+ F G AA++ ++ I+ G+ ++ + Sbjct: 71 NGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTA 130 Query: 181 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS 240 Y S S+++ + GV + ++ + P TK+V+LESP + ++ D+ I Sbjct: 131 YEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIV 190 Query: 241 EMAHA--QGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKG--- 295 + A++++DN+ + VL + L+ G D+ + +ATK++ GHSD M G Sbjct: 191 AAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCW 250 Query: 296 EKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKV 355 E+L + Y + G + ++ RG++T+ +R+ + E++ K+A +L+ HP+V +V Sbjct: 251 EQLRENAYLM----GQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARV 306 Query: 356 YYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHL---VETTKYFSIAVSFGSVKSL 412 + LP GH G+ +FSF+ ++ L ++ FS+A S+G +SL Sbjct: 307 NHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESL 366 Query: 413 ISMPCFMSHASIPAEVREARGLTE-----DLVRISAGIEDVDDLISDLDIAF 459 I A+ P + R E L+R+ G+EDVDDLI+DLD F Sbjct: 367 IL-------ANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGF 411 >1U08-A nrPDB Length = 386 Score = 41.6 bits (96), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 41/150 (27%), Positives = 60/150 (40%), Gaps = 19/150 (12%) Query: 92 VNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDAL----ESLLAKLDK 147 +NL F FD P Y A Y R+A+ E L Sbjct: 33 INLSQGFPDFDG---PRYLQERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPD 89 Query: 148 ADRAFCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVN-- 203 AD T+G A +A+T L++NG+E++ D Y + + SG +VKR+ Sbjct: 90 ADSDITVTAGATEALYAAITALVRNGDEVICFDPSYDS----YAPAIALSGGIVKRMALQ 145 Query: 204 ----TTKLDEVAAAIGPQTKLVWLESPTNP 229 E AA + +T+LV L +P NP Sbjct: 146 PPHFRVDWQEFAALLSERTRLVILNTPHNP 175 >5XT5-A nrPDB Length = 419 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 11/117 (9%) Query: 154 FTSG------MAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV----- 202 FT G M ALS +K G+E+V + + Q V +G +K + Sbjct: 91 FTKGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQED 150 Query: 203 NTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSP 259 T L++V + TK+V + +N ++ I++++++AH GA+++VD + +P Sbjct: 151 GTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTP 207 >3JUL-A nrPDB Length = 320 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 10/109 (9%) Query: 174 IVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKL-DEVAAAIGPQTKLVWLESPTNPRQQ 232 +V DD G S ++P +G V + N L ++A + + +V SP P Sbjct: 96 VVLSDDTNG------STMIPEAGFTVSQTNKDNLLKQIAKKVKKEDMVVIAGSPP-PHYT 148 Query: 233 ISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIA 281 +SD +++ A GA + DNS L+ +E+G D + + + IA Sbjct: 149 LSDFKELLRTVKATGAFLGCDNS--GEYLNLAVEMGVDFIKPNEDEVIA 195 >4W91-A nrPDB Length = 422 Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 51/97 (52%), Gaps = 8/97 (8%) Query: 207 LDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS---IMSPVLSR 263 ++E + +TKLV + +N + I+KI E+AHA+G VLVD S + PV + Sbjct: 170 IEEFEKRLSERTKLVAITHMSNTLGTVVPIKKIVELAHARGIPVLVDGSQGAVHLPVDVQ 229 Query: 264 PLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK 300 +LG D + + K + G S + GVL + + L K Sbjct: 230 --DLGCDWYVFTGHK-VYGPSGI--GVLYGRAQMLEK 261 >3CAI-A nrPDB Length = 406 Score = 34.7 bits (78), Expect = 0.096, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 29/46 (63%) Query: 214 IGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSP 259 I T+LV + S + ++D+R ++++ H GALV+VD+S +P Sbjct: 162 ISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAP 207 >2AEV-A nrPDB Length = 374 Score = 33.9 bits (76), Expect = 0.16, Method: Compositional matrix adjust. Identities = 43/158 (27%), Positives = 73/158 (46%), Gaps = 13/158 (8%) Query: 192 VPRSGVVV--KRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQ-QISDIRKISEMAHAQGA 248 + RS +V K + K+ E+ I T ++ S + + ++ + +K+ A + A Sbjct: 114 IERSCKIVNAKYFESDKVGEILNKIDKDTLVIITGSTMDLKVIELENFKKVINTAKNKEA 173 Query: 249 LVLVDNSIMSPV---LSRP--LELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVY 303 +V VD++ + V ++P L+LGAD+V+ S K + G G+LA K E L ++Y Sbjct: 174 IVFVDDASGARVRLLFNQPPALKLGADLVVTSTDKLMEGPR---GGLLAGKKE-LVDKIY 229 Query: 304 FLQNSEGSGLAPFDCWLCLRGIKTMAL-RIEKQQENAR 340 G P R +K L RI K E A+ Sbjct: 230 IEGTKFGLEAQPPLLAGIYRALKNFNLERIRKAFERAK 267 >5OLJ-A nrPDB Length = 723 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Query: 51 FKLNCVMEKSVDGQTHSTVNNTTDSLNTMNIKEEASVSTLL-VNLDNKFDPF---DAMST 106 F + ++ + DGQ +S +N TD + +EE V+ L+ + DN F F D + Sbjct: 167 FDFDTEVQVTTDGQINSVLNGATDWV----YEEEFGVTNLMSWSADNAFLAFVRSDESAV 222 Query: 107 PLYQTATFKQPSAIENGPYDYTRSG 131 P Y+ ++ E+ Y Y ++G Sbjct: 223 PEYRMPMYEDKLYPEDYTYKYPKAG 247 >1J32-A nrPDB Length = 388 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 19/153 (12%) Query: 118 SAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCF-------TSG--MAALSAVTHLI 168 +A+E G Y + R L +A+ + D C+ T+G + + + +I Sbjct: 54 AALEQGKTRYGPAAGEPR--LREAIAQKLQRDNGLCYGADNILVTNGGKQSIFNLMLAMI 111 Query: 169 KNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKL----DEVAAAIGPQTKLVWLE 224 + G+E++ + ++ ++ + V++ T+ +++ AI P+TKL+ Sbjct: 112 EPGDEVIIPAPFWVSYPEMV-KLAEGTPVILPTTVETQFKVSPEQIRQAITPKTKLLVFN 170 Query: 225 SPTNPRQQI---SDIRKISEMAHAQGALVLVDN 254 +P+NP + ++R I+++A G VL D Sbjct: 171 TPSNPTGMVYTPDEVRAIAQVAVEAGLWVLSDE 203 >6HRH-B nrPDB Length = 469 Score = 32.3 bits (72), Expect = 0.42, Method: Compositional matrix adjust. Identities = 50/215 (23%), Positives = 88/215 (40%), Gaps = 13/215 (6%) Query: 49 NSFKLNCVMEKSVDG--QTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMST 106 + F + +MEK D + TVN D+ EASV++ V++ D Sbjct: 28 DQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRH 87 Query: 107 PLYQTATFK--QPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAV 164 P AT + Q + G + LE LA+L + D A F+S A + Sbjct: 88 PQVLQATQETLQRHGVGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDST 147 Query: 165 THLIKNGEEIVAGDDVY--GGSDRLLSQVVPRSGV---VVKRVNTTKLDEVAAAIGPQT- 218 + +I+ G ++Y G+ + Q + SG V + + L ++ P+ Sbjct: 148 LFTLA---KILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIP 204 Query: 219 KLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD 253 K+V E+ + I + ++ +++H GAL VD Sbjct: 205 KIVAFETVHSMDGAICPLEELCDVSHQYGALTFVD 239 >4AC8-A nrPDB Length = 323 Score = 32.3 bits (72), Expect = 0.46, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 20/100 (20%) Query: 270 DIVMHSATKFIAGHS----DVMAGVLAVKGE-KLAKEVYFLQNS--EGSGLAPFDCWLCL 322 D T+FIAG D+ + A++ E +LA E+Y Q + E F WL Sbjct: 64 DYATRLCTQFIAGEEAVTEDIQPFMSAMRAEGRLADEMYLTQFAFEEAKHTQVFRMWLDA 123 Query: 323 RGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPD 362 GI + + YL P ++++YA LP+ Sbjct: 124 VGI-------------SEDLHRYLDDLPAYRQIFYAELPE 150 >4Q75-A nrPDB Length = 429 Score = 32.3 bits (72), Expect = 0.47, Method: Compositional matrix adjust. Identities = 37/131 (28%), Positives = 60/131 (45%), Gaps = 20/131 (15%) Query: 177 GDDVYGGSDRLLSQVVP------RSGVVVKRVNTTK-----LDEVAAAIGPQTKLVWLES 225 GD+V S +VP ++G V+K V + ++++ I P+TKLV + Sbjct: 128 GDEVILTVAEHHSCIVPWQIVSQKTGAVLKFVTLNEDEVPDINKLRELISPKTKLVAVHH 187 Query: 226 PTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLE-LGADIVMHSATK------ 278 +N I +I AH GA VLVD P + ++ L AD ++ S+ K Sbjct: 188 VSNVLASSLPIEEIVVWAHDVGAKVLVDACQSVPHMVVDVQKLNADFLVASSHKMCGPTG 247 Query: 279 --FIAGHSDVM 287 F+ G SD++ Sbjct: 248 IGFLYGKSDLL 258 >5TXT-B nrPDB Length = 491 Score = 32.0 bits (71), Expect = 0.56, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 5/120 (4%) Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHLI--KNGEEIVAGDDVYGGSDRLLSQVVPRS 195 LE+ LA L K + A F+S A AV L+ K + ++ D++ S + + Sbjct: 106 LEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVK 165 Query: 196 GVVVKRVNTTKLDEVAAAIGPQT--KLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD 253 + K + +L+++ + P++ KL+ ES + ++DI KI ++A GAL +D Sbjct: 166 KHIFKHNDLNELEQLLQSY-PKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLD 224 >1T3I-A nrPDB Length = 420 Score = 32.0 bits (71), Expect = 0.60, Method: Compositional matrix adjust. Identities = 33/152 (21%), Positives = 66/152 (43%), Gaps = 15/152 (9%) Query: 168 IKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTK-----LDEVAAAIGPQTKLVW 222 +K G+EI+ + + V ++G V+K V + L+ + +TKLV Sbjct: 115 LKAGDEIITTVMEHHSNLVPWQMVAAKTGAVLKFVQLDEQESFDLEHFKTLLSEKTKLVT 174 Query: 223 LESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLEL---------GADIVM 273 + +N ++ +I+++AH GA VLVD +P ++L G + Sbjct: 175 VVHISNTLGCVNPAEEIAQLAHQAGAKVLVDACQSAPHYPLDVQLIDCDWLVASGHKMCA 234 Query: 274 HSATKFIAGHSDVMAGVLA-VKGEKLAKEVYF 304 + F+ G +++ + G ++ EV+F Sbjct: 235 PTGIGFLYGKEEILEAMPPFFGGGEMIAEVFF 266 >4LHD-A nrPDB Length = 983 Score = 31.2 bits (69), Expect = 0.88, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 3/67 (4%) Query: 233 ISDIRKISEMAHAQGALV-LVDNSIMSPVLSRPLELGADIVMHSATKF--IAGHSDVMAG 289 + D R + AH ALV L + + +L+ P ELGADI + S +F G+ A Sbjct: 244 VYDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRFGIPLGYGGPHAA 303 Query: 290 VLAVKGE 296 A K E Sbjct: 304 YFATKAE 310 >6F35-A nrPDB Length = 410 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 20/92 (21%) Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGV 197 +++A LD D T + S + H+ + ++A D G Sbjct: 115 FNAMMASLDPGDEVIIPTPYWTSYSDIVHICEGKPVLIACDASSG--------------- 159 Query: 198 VVKRVNTTKLDEVAAAIGPQTKLVWLESPTNP 229 R+ KL+ AAI P+T+ V L SP+NP Sbjct: 160 --FRLTAEKLE---AAITPRTRWVLLNSPSNP 186 >2CKS-A nrPDB Length = 306 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 5/57 (8%) Query: 227 TNPRQQISDIRKISEMAHAQGALVLVDNSIMSPV-----LSRPLELGADIVMHSATK 278 TNPR + ++ +MA A+G V+VD I++P L R A+I A+K Sbjct: 73 TNPRGFTDRMHQLIDMATARGLYVIVDWHILTPGDPHYNLDRAKTFFAEIAQRHASK 129 >6C9E-A nrPDB Length = 422 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 27/49 (55%) Query: 207 LDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS 255 L+E + TK+V + +N I+ ++ + +MAH GA VL+D + Sbjct: 170 LEEFERKLNENTKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGA 218 >3FFH-A nrPDB Length = 363 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 26/191 (13%) Query: 207 LDEVAAAIGPQTKLVWLESPTNPRQ---QISDIRKISEMAHAQGALVLVDNSIMSPVLSR 263 L+ + AI +T +VW+ +P NP +++DI+ + + LV++D + + V + Sbjct: 145 LEGMLNAIDEKTTIVWICNPNNPTGNYIELADIQAFLDRVPSD-VLVVLDEAYIEYVTPQ 203 Query: 264 P------LELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFD 317 P + ++++ I G + G + +++ +++ ++ PF+ Sbjct: 204 PEKHEKLVRTYKNLIITRTFSKIYGLASARVG-YGIADKEIIRQLNIVR-------PPFN 255 Query: 318 CW-----LCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQ 372 L + IK A E + NA I Y + R +KV L G+ + Sbjct: 256 TTSIGQKLAIEAIKDQAFIGECRTSNANGIKQYEAFAKRFEKV---KLYPANGNFVLIDL 312 Query: 373 AKGAGSVFSFI 383 AG++FS++ Sbjct: 313 GIEAGTIFSYL 323 >4BMK-A nrPDB Length = 442 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 17/114 (14%) Query: 151 AFCFTSG-MAALSAVTHLIKNGEEIVAGDD----VYGGSDRLLSQVVPRSGVVVKRVNTT 205 A F++G MA L ++ L GE ++ D +Y G + +++V R Sbjct: 149 AIVFSTGYMANLGIISTLAGKGEYVILDADSHASIYDGCQQGNAEIV--------RFRHN 200 Query: 206 KLDEVAAAIG--PQ--TKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS 255 ++++ +G P+ KLV LE + I+ ++++ +A GA+VLVD + Sbjct: 201 SVEDLDKRLGRLPKEPAKLVVLEGVYSMLGDIAPLKEMVAVAKKHGAMVLVDEA 254 >2XPY-A nrPDB Length = 632 Score = 29.3 bits (64), Expect = 4.1, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 14/86 (16%) Query: 39 TWEKKQISN--RNSFKLN----CVMEKSVDGQTH-------STVNNTTDSLNTMN-IKEE 84 +W ++N N F LN +E+ + G H S + +D N+++ +K+ Sbjct: 306 SWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIHGEPTRHFSALIGWSDLQNSIDSMKDP 365 Query: 85 ASVSTLLVNLDNKFDPFDAMSTPLYQ 110 STL+ NL++ DP DA ST Y+ Sbjct: 366 ERFSTLVQNLNDNTDPDDAFSTVPYE 391 >4UX8-A nrPDB Length = 607 Score = 28.1 bits (61), Expect = 7.4, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 6/62 (9%) Query: 146 DKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT 205 D+ D A F +G+ SAV + + +VA V+ + VVP SG +V+R +T Sbjct: 236 DEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD------ADVVPASGELVRRYTST 289 Query: 206 KL 207 L Sbjct: 290 LL 291 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1IBJ-A nrPDB 722 0.0 3MKJ-A nrPDB 556 e-159 4IYO-A nrPDB 555 e-158 4L0O-H nrPDB 553 e-158 1E5F-A nrPDB 549 e-156 5DX5-A nrPDB 537 e-153 6CJB-A nrPDB 526 e-150 5X5H-A nrPDB 525 e-149 3VK2-A nrPDB 519 e-148 5TSU-A nrPDB 519 e-147 3AEO-A nrPDB 510 e-145 1N8P-A nrPDB 499 e-141 1CS1-A nrPDB 497 e-141 3QI6-A nrPDB 496 e-140 1PFF-A nrPDB 478 e-135 4U1T-A nrPDB 460 e-130 1I43-A nrPDB 457 e-129 4OC9-A nrPDB 454 e-128 3NDN-A nrPDB 454 e-128 2CTZ-A nrPDB 447 e-126 4KAM-A nrPDB 447 e-126 3RI6-A nrPDB 417 e-117 2CB1-A nrPDB 408 e-114 5IJG-A nrPDB 407 e-114 2FQ6-A nrPDB 375 e-104 1U08-A nrPDB 118 7e-27 Sequences not found previously or not previously below threshold: 1V2E-A nrPDB 71 1e-12 3NYS-A nrPDB 69 3e-12 1M6S-A nrPDB 67 1e-11 2O0R-A nrPDB 65 8e-11 1YIY-A nrPDB 64 2e-10 3UWC-A nrPDB 63 2e-10 3CAI-A nrPDB 60 2e-09 3OP7-A nrPDB 60 3e-09 1J32-A nrPDB 58 6e-09 4WP0-A nrPDB 58 8e-09 3FVS-A nrPDB 58 8e-09 4BMK-A nrPDB 57 1e-08 2ZJG-A nrPDB 57 1e-08 1MDZ-A nrPDB 57 2e-08 3LVM-A nrPDB 57 2e-08 2OGE-A nrPDB 57 2e-08 5TXT-B nrPDB 56 4e-08 5W70-A nrPDB 55 7e-08 2Z61-A nrPDB 55 7e-08 3B46-A nrPDB 55 9e-08 4Q75-A nrPDB 54 1e-07 6HRH-B nrPDB 54 1e-07 3W1J-A nrPDB 54 2e-07 3W1H-A nrPDB 54 2e-07 2GB3-A nrPDB 53 2e-07 5XT5-A nrPDB 53 3e-07 1T3I-A nrPDB 52 4e-07 1O4S-A nrPDB 52 5e-07 1GC4-A nrPDB 52 7e-07 3WGB-A nrPDB 51 9e-07 4MY5-A nrPDB 51 1e-06 1GDE-A nrPDB 50 2e-06 4W91-A nrPDB 50 2e-06 4M2J-A nrPDB 50 2e-06 3WY7-A nrPDB 48 6e-06 2AEV-A nrPDB 48 6e-06 2DOU-A nrPDB 48 1e-05 3BB8-A nrPDB 47 1e-05 5HH9-A nrPDB 47 2e-05 3PDX-A nrPDB 47 2e-05 1XI9-A nrPDB 46 2e-05 5WMH-A nrPDB 46 3e-05 3DYD-A nrPDB 46 3e-05 2X8U-A nrPDB 46 4e-05 1B9H-A nrPDB 46 4e-05 5YHV-A nrPDB 46 4e-05 1BW0-A nrPDB 45 5e-05 3L8A-A nrPDB 45 5e-05 3PJ0-A nrPDB 45 6e-05 2C81-A nrPDB 45 6e-05 4PIW-A nrPDB 45 9e-05 2YRI-A nrPDB 44 1e-04 6F35-A nrPDB 43 2e-04 2O1B-A nrPDB 43 2e-04 4ZWV-A nrPDB 43 3e-04 2X5D-A nrPDB 43 4e-04 3EUC-A nrPDB 43 4e-04 4P3M-A nrPDB 43 4e-04 6BLG-A nrPDB 42 5e-04 4IX8-A nrPDB 42 5e-04 3MAF-B nrPDB 42 6e-04 3H7F-A nrPDB 41 9e-04 3DZZ-A nrPDB 41 0.001 4WXB-A nrPDB 40 0.002 2HUU-A nrPDB 40 0.002 3LWS-A nrPDB 40 0.003 2FNU-A nrPDB 40 0.003 5DJ3-A nrPDB 40 0.003 3JTX-A nrPDB 40 0.003 1D2F-A nrPDB 40 0.003 5WGB-A nrPDB 39 0.004 4CVQ-A nrPDB 39 0.004 6C9E-A nrPDB 39 0.004 3FFH-A nrPDB 39 0.005 1LC8-A nrPDB 39 0.005 4FL0-A nrPDB 39 0.005 3A2B-A nrPDB 39 0.005 3N0L-A nrPDB 38 0.008 6MRE-A nrPDB 38 0.008 1YJS-A nrPDB 38 0.009 3ISL-A nrPDB 38 0.010 3G8M-A nrPDB 38 0.012 1IJI-A nrPDB 38 0.012 1DJ9-A nrPDB 38 0.013 5JAY-A nrPDB 38 0.013 5VNX-A nrPDB 37 0.014 3IF2-A nrPDB 37 0.015 6F77-B nrPDB 37 0.016 2ZC0-A nrPDB 37 0.016 2EZ1-A nrPDB 37 0.019 3H14-A nrPDB 37 0.020 6ONN-A nrPDB 37 0.022 4Q6R-A nrPDB 36 0.023 5WT2-A nrPDB 36 0.024 2Z9W-A nrPDB 36 0.025 4R2N-A nrPDB 36 0.027 4LW2-A nrPDB 36 0.029 3FDB-A nrPDB 36 0.030 3CQ5-A nrPDB 36 0.032 5VMB-A nrPDB 36 0.043 3MC6-C nrPDB 35 0.059 3T32-A nrPDB 34 0.16 3TQX-A nrPDB 33 0.21 3QGU-A nrPDB 33 0.22 3HDO-A nrPDB 33 0.27 4WBT-A nrPDB 33 0.32 3KE3-A nrPDB 33 0.34 1C7O-A nrPDB 33 0.34 5UIA-A nrPDB 32 0.45 4MJM-A nrPDB 32 0.46 3TSB-A nrPDB 32 0.46 3RUY-A nrPDB 32 0.48 3ELE-A nrPDB 32 0.66 2PV7-A nrPDB 31 0.77 6HBE-A nrPDB 31 0.91 4QJ1-A nrPDB 31 0.91 3FFS-A nrPDB 31 0.91 3NX3-A nrPDB 31 0.95 3AII-A nrPDB 31 1.0 3EZS-A nrPDB 31 1.2 1UU1-A nrPDB 31 1.4 6JEQ-A nrPDB 30 1.7 1T6J-A nrPDB 30 1.8 4DUT-A nrPDB 30 2.1 3EI8-A nrPDB 30 2.2 4RAS-A nrPDB 30 2.7 5VOO-A nrPDB 30 2.8 6C3C-A nrPDB 30 3.0 3QYQ-A nrPDB 30 3.1 3GET-A nrPDB 30 3.2 4LHD-A nrPDB 29 4.4 4LIS-A nrPDB 28 6.9 4MOP-A nrPDB 28 6.9 3AHE-A nrPDB 28 7.2 2WVK-A nrPDB 28 7.5 5ZR1-C nrPDB 28 7.7 3WLO-A nrPDB 28 9.0 5G2X-C nrPDB 28 9.5 >1IBJ-A nrPDB Length = 464 Score = 722 bits (1865), Expect = 0.0, Method: Composition-based stats. Identities = 464/464 (100%), Positives = 464/464 (100%) Query: 1 MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKS 60 MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKS Sbjct: 1 MTSSLSLHSSFVPSFADLSDRGLISKNSPTSVSISKVPTWEKKQISNRNSFKLNCVMEKS 60 Query: 61 VDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI 120 VDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI Sbjct: 61 VDGQTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI 120 Query: 121 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV 180 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV Sbjct: 121 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV 180 Query: 181 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS 240 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS Sbjct: 181 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIS 240 Query: 241 EMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK 300 EMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK Sbjct: 241 EMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK 300 Query: 301 EVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGL 360 EVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGL Sbjct: 301 EVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGL 360 Query: 361 PDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420 PDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS Sbjct: 361 PDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420 Query: 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL 464 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL Sbjct: 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTFPL 464 >3MKJ-A nrPDB Length = 398 Score = 556 bits (1433), Expect = e-159, Method: Composition-based stats. Identities = 151/388 (38%), Positives = 238/388 (61%), Gaps = 12/388 (3%) Query: 86 SVSTLLVNLDNKFDP-FDAMSTPLYQTATFKQPSA--------IENGPYDYTRSGNPTRD 136 +T +V+ + DP A+STP++QT+TF SA +E Y YTR GNPT D Sbjct: 8 GFNTQIVHAGQQPDPSTGALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTD 67 Query: 137 ALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRS 195 ALE LA L++ + SG++A++ + L + G+ IV+ +YG + LS +P+ Sbjct: 68 ALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLSHSMPKF 127 Query: 196 GVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS 255 G+ V V+ K +E+ AA+ P+TK+V++E+P NP + DI ++ +AH QGAL++VDN+ Sbjct: 128 GINVSFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGALLVVDNT 187 Query: 256 IMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEGSGLA 314 MSP +PL+LGADIV+HS TK+I GH DV+ G++ K E + + L++ G ++ Sbjct: 188 FMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDITGGCMS 247 Query: 315 PFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAK 374 PF+ WL LRG+KT+ +R+E+ ENA KIA +L HP + +VYY GL HP + L Q Sbjct: 248 PFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQMS 307 Query: 375 GAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARG 433 G + SF I G + + ++ + + +AVS G ++LI P M+H+ + E R G Sbjct: 308 LPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLKAG 367 Query: 434 LTEDLVRISAGIEDVDDLISDLDIAFKT 461 +T+ L+R+S G+ED +D+I+DL+ A + Sbjct: 368 ITDGLIRLSVGLEDPEDIINDLEHAIRK 395 >4IYO-A nrPDB Length = 397 Score = 555 bits (1431), Expect = e-158, Method: Composition-based stats. Identities = 170/394 (43%), Positives = 240/394 (60%), Gaps = 7/394 (1%) Query: 70 NNTTDSLNTMNIKEEASVSTLLVNLDNKFDP-FDAMSTPLYQTATFKQPSAIENGPYDYT 128 N TT S + S++TL ++ DP A+ P+Y T+T+ Q S E+ ++Y+ Sbjct: 3 NRTTHSHDG---DRALSLATLAIHGGQSPDPSTGAVMPPIYATSTYAQSSPGEHQGFEYS 59 Query: 129 RSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLL 188 R+ NPTR A E +A L+ RAF F SGMAA S V L+ G +VA DD+YGG+ RL Sbjct: 60 RTHNPTRFAYERCVAALEGGTRAFAFASGMAATSTVMELLDAGSHVVAMDDLYGGTFRLF 119 Query: 189 SQVVPRS-GVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQG 247 +V R+ G+ V+ T AAI TK+VW+E+PTNP ++ DI I+ +A G Sbjct: 120 ERVRRRTAGLDFSFVDLTDPAAFKAAIRADTKMVWIETPTNPMLKLVDIAAIAVIARKHG 179 Query: 248 ALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKG-EKLAKEVYFLQ 306 L +VDN+ SP+L RPL LGAD+V+HSATK++ GHSD++ G+ V +LA+++ FLQ Sbjct: 180 LLTVVDNTFASPMLQRPLSLGADLVVHSATKYLNGHSDMVGGIAVVGDNAELAEQMAFLQ 239 Query: 307 NSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGH 366 NS G PFD +L LRG+KT+ LR+ ENA +A +L +HP ++KV Y GL HP H Sbjct: 240 NSIGGVQGPFDSFLALRGLKTLPLRMRAHCENALALAQWLETHPAIEKVIYPGLASHPQH 299 Query: 367 HLHFSQAKGAGSVFS-FITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIP 425 L Q G G + S + G +K E T+ F++A S G V+SL++ P M+HASIP Sbjct: 300 VLAKRQMSGFGGIVSIVLKGGFDAAKRFCEKTELFTLAESLGGVESLVNHPAVMTHASIP 359 Query: 426 AEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 RE G+++ LVR+S GIED+ DL DL+ A Sbjct: 360 VARREQLGISDALVRLSVGIEDLGDLRGDLERAL 393 >4L0O-H nrPDB Length = 388 Score = 553 bits (1426), Expect = e-158, Method: Composition-based stats. Identities = 162/381 (42%), Positives = 243/381 (63%), Gaps = 1/381 (0%) Query: 85 ASVSTLLVNLDNKFD-PFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLA 143 + T L++ D A+S P+YQT+T++Q + + Y+Y+RSGNPTR ALE L+A Sbjct: 1 MRMQTKLIHGGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIA 60 Query: 144 KLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVN 203 L+ + F F SG+A + AV L+++G+ ++ GDDVYGG+ RL +QV+ ++G+ ++ Sbjct: 61 DLEGGVKGFAFASGLAGIHAVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIID 120 Query: 204 TTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSR 263 T+ + ++ AI P TK ++LE+P+NP +I+D+ + + +A G L +VDN+ +P Sbjct: 121 TSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFATPYYQN 180 Query: 264 PLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLR 323 PL LGADIV HS TK++ GHSDV+AG++ E LA+E+ F QN+ G L P D WL R Sbjct: 181 PLLLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR 240 Query: 324 GIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFI 383 GIKT+ LR+E Q+NA +A +L HP+V++VYY GLP HP + L Q +G + SF Sbjct: 241 GIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSGMLSFT 300 Query: 384 TGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISA 443 + + + VE+ K F + S G V+SL+ +P FM+HA IP REA G+ + LVR+S Sbjct: 301 LKNDSEAVAFVESLKLFILGESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVRLSV 360 Query: 444 GIEDVDDLISDLDIAFKTFPL 464 GIE DL+ DL+ AF L Sbjct: 361 GIEHEQDLLEDLEQAFAKIGL 381 >1E5F-A nrPDB Length = 404 Score = 549 bits (1414), Expect = e-156, Method: Composition-based stats. Identities = 146/393 (37%), Positives = 234/393 (59%), Gaps = 12/393 (3%) Query: 82 KEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPS--------AIENGPYDYTRSGNP 133 E + +T ++ + + D F A P+YQT+TF + A + Y YTR GNP Sbjct: 3 HERMTPATACIHANPQKDQFGAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNP 62 Query: 134 TRDALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192 T LE +A L+K + +SGM A++A V ++K G+ +++ + +YG + L + Sbjct: 63 TVSNLEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHAL 122 Query: 193 PRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ-GALVL 251 + G+ V +NT EV + P TK+V+ E+P NP +I D+ ++ + AH+Q G LV+ Sbjct: 123 TKFGIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHSQEGVLVI 182 Query: 252 VDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEG 310 DN+ SP+++ P++ G D+V+HSATK+I GH+DV+AG++ K + L + + +++ G Sbjct: 183 ADNTFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDITG 242 Query: 311 SGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHF 370 S ++P D WL RG+ T+ +R++ + ENA K+A YL SHP V+KVYY G DH GH + Sbjct: 243 SVISPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAK 302 Query: 371 SQAKGAGSVFSFITG-SVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVR 429 Q + GS+ +FI +K L++ K ++AVS G +SLI P M+HA +P E R Sbjct: 303 KQMRMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEER 362 Query: 430 EARGLTEDLVRISAGIEDVDDLISDLDIAFKTF 462 EA G+T+ ++R+S GIED D+LI+D Sbjct: 363 EAAGITDGMIRLSVGIEDADELIADFKQGLDAL 395 >5DX5-A nrPDB Length = 400 Score = 537 bits (1383), Expect = e-153, Method: Composition-based stats. Identities = 155/394 (39%), Positives = 239/394 (60%), Gaps = 14/394 (3%) Query: 83 EEASVSTLLVNLDN-KFDPFDAMSTPLYQTATFKQPSA--------IENGPYDYTRSGNP 133 ++ +T ++ + F +++TP+YQT+TF SA E Y Y+R GNP Sbjct: 5 KKMGFATKAIHGGHIGDKQFGSLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNP 64 Query: 134 TRDALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192 T +E+ LA L+ + A SGM A++A + +K+G+ +VA D +YG + LL+ + Sbjct: 65 TSTEVENKLALLEGGEAAVVAASGMGAIAASLWSALKSGDHVVASDTLYGCTFALLNHGL 124 Query: 193 PRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHA--QGALV 250 R GV V V+ + LDEV A+ P TK+V+LE+P NP +++DIRKIS M H + V Sbjct: 125 TRYGVEVTFVDVSNLDEVKNALKPNTKVVYLETPANPTLKVTDIRKISNMVHESNKECFV 184 Query: 251 LVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSE 309 VDN+ +P + RPLELGAD+V+HSATK++ GH DV+AG K E + + +++ +++ Sbjct: 185 FVDNTFCTPYIQRPLELGADVVVHSATKYLNGHGDVIAGFAVGKEEFINQVKLFGIKDMT 244 Query: 310 GSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLH 369 GS PF+ +L +RG+KT+ LR+EK +NA ++A +L SHP V+KVYY GL + L Sbjct: 245 GSVTGPFESFLIIRGMKTLQLRMEKHCKNAMEVAKFLESHPAVEKVYYPGLESFKYYQLA 304 Query: 370 FSQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEV 428 Q K G++ SF + G V K ++ K ++AVS G ++LI P M+H+ AE Sbjct: 305 REQMKLPGAMISFELKGGVEEGKIVMNNVKLATLAVSLGDSETLIQHPASMTHSPYTAEE 364 Query: 429 REARGLTEDLVRISAGIEDVDDLISDLDIAFKTF 462 R+A G+++ LVR+S G+ED +D+I DL A Sbjct: 365 RKAAGISDGLVRLSVGLEDAEDIIDDLKQALDLI 398 >6CJB-A nrPDB Length = 391 Score = 526 bits (1355), Expect = e-150, Method: Composition-based stats. Identities = 154/377 (40%), Positives = 242/377 (64%), Gaps = 4/377 (1%) Query: 87 VSTLLVNLDNKF-DPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKL 145 T ++ + A+ TP+Y T+T+KQ + E+ Y+Y+R+ NPTR A E +A L Sbjct: 14 FDTRAIHAGQEPCKSTGAVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIASL 73 Query: 146 DKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPR-SGVVVKRVNT 204 + + F F SGMAA++ V L+ +G+ +VA DD+YGG+ RL +V R S + ++ Sbjct: 74 ESGQKGFAFASGMAAINTVIDLLGSGDHVVAMDDLYGGTFRLFDKVKTRTSNLSFSFIDM 133 Query: 205 TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRP 264 + + + AAI P+TKL+WLE+P+NP +++++RKI+ +A + + DN+ +P + RP Sbjct: 134 SVPENIEAAITPKTKLLWLETPSNPMLKLANLRKIAAIAKKYNLITVADNTFATPWIQRP 193 Query: 265 LELGADIVMHSATKFIAGHSDVMAGVLAVKGEK-LAKEVYFLQNSEGSGLAPFDCWLCLR 323 LELG DIV+HSATK++ GHSDV++GV+ V L+ ++ FLQNS G+ PFD +L LR Sbjct: 194 LELGFDIVLHSATKYLNGHSDVVSGVVVVGDNSVLSDKIAFLQNSCGAVAGPFDSFLVLR 253 Query: 324 GIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFI 383 +KT+++R+++ ENA +A +LSSHP+++KV Y GL HP + L Q G + S + Sbjct: 254 SLKTLSVRMQRHCENANHLANWLSSHPKIEKVIYPGLKSHPQYSLAKEQMNNFGGMISLV 313 Query: 384 -TGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRIS 442 GS+ +K + + F++A S G V+SLI P M+HASIP E R+A G+ + +R+S Sbjct: 314 LKGSLEDAKRFLARCELFTLAESLGGVESLIEHPAIMTHASIPVEQRKALGIEDGFIRLS 373 Query: 443 AGIEDVDDLISDLDIAF 459 GIE +DDL +DL+ A Sbjct: 374 VGIEHIDDLRADLEHAL 390 >5X5H-A nrPDB Length = 392 Score = 525 bits (1353), Expect = e-149, Method: Composition-based stats. Identities = 150/381 (39%), Positives = 225/381 (59%), Gaps = 7/381 (1%) Query: 86 SVSTLLVNLDNKFDPF-DAMSTPLYQTATFKQPSAIE-NGPYDYTRSGNPTRDALESLLA 143 ST ++ + D + +++TP+Y + TF Q + E Y+YTR GNPT ALE +A Sbjct: 9 GFSTASIHAGYEPDDYYGSINTPIYASTTFAQNAPNELRKGYEYTRVGNPTIVALEQTVA 68 Query: 144 KLDKADRAFCFTSGMAALSAVTHL-IKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV 202 L+ A F+SGMAA + + +K G+ IV G+D YGG+ RL+ V GV V Sbjct: 69 ALEGAKYGRAFSSGMAATDILFRIILKPGDHIVLGNDAYGGTYRLIDTVFTAWGVEYTVV 128 Query: 203 NTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLS 262 +T+ ++EV AAI TKL+W+E+PTNP I+DI ++++ A ++VDN+ SP L Sbjct: 129 DTSVVEEVKAAIKDNTKLIWVETPTNPALGITDIEAVAKLTEGTNAKLVVDNTFASPYLQ 188 Query: 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCL 322 +PL+LGA V+HS TK+I GHSDV+ G++ +++ +E+ F+Q G + FD +L Sbjct: 189 QPLKLGAHAVLHSTTKYIGGHSDVVGGLVVTNDQEMDEELLFMQGGIGPIPSVFDAYLTA 248 Query: 323 RGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF 382 RG+KT+A+R+++ +NA KIA +L S P V V Y GL +HPGH + Q K G + S Sbjct: 249 RGLKTLAVRMDRHCDNAEKIAEFLDSRPEVSTVLYPGLKNHPGHEVAAKQMKRFGGMISV 308 Query: 383 -ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRI 441 G +K +TK +A S G V+SL+ P M+H S E + DLVRI Sbjct: 309 RFAGGEEAAKKFCTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQLE---VPRDLVRI 365 Query: 442 SAGIEDVDDLISDLDIAFKTF 462 S GIED++DL++D++ A Sbjct: 366 SIGIEDIEDLLADVEQALNNL 386 >3VK2-A nrPDB Length = 398 Score = 519 bits (1338), Expect = e-148, Method: Composition-based stats. Identities = 132/391 (33%), Positives = 223/391 (57%), Gaps = 12/391 (3%) Query: 82 KEEASVSTLLVNLDNKFDPFD-AMSTPLYQTATFKQPS--------AIENGPYDYTRSGN 132 + +T ++ A+ P+YQTATF P+ A E + Y+R N Sbjct: 5 NKLPGFATRAIHHGYDPQDHGGALVPPVYQTATFTFPTVEYGAACFAGEQAGHFYSRISN 64 Query: 133 PTRDALESLLAKLDKADRAFCFTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQV 191 PT + LE+ +A L+ + SGM A++ + L++ G+E++ G+ +YG + L Sbjct: 65 PTLNLLEARMASLEGGEAGLALASGMGAITSTLWTLLRPGDEVLLGNTLYGHTFAFLHHG 124 Query: 192 VPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL 251 + GV ++ V+ L + AA+ P T++++ ESP NP ++DI ++++A GA V+ Sbjct: 125 IGEFGVKLRHVDMADLQALEAAMTPATRVIYFESPANPNMHMADIAGVAKIARKHGATVV 184 Query: 252 VDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEG 310 VDN+ +P L RPLELGAD+V+HSATK+++GH D+ AG++ + + + L++ G Sbjct: 185 VDNTYCTPYLQRPLELGADLVVHSATKYLSGHGDITAGIVVGSQALVDRIRLQGLKDMTG 244 Query: 311 SGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHF 370 + L+P D L +RGIKT+ LR+++ NA+ +A +L+ P+V+ ++Y GL P + L Sbjct: 245 AVLSPHDAALLMRGIKTLNLRMDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLAR 304 Query: 371 SQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVR 429 Q G + +F + G + + + + FS AVS G +SL P M+H+S E R Sbjct: 305 QQMSQPGGMIAFELKGGIGAGRRFMNALQLFSRAVSLGDAESLAQHPASMTHSSYTPEER 364 Query: 430 EARGLTEDLVRISAGIEDVDDLISDLDIAFK 460 G++E LVR+S G+ED+DDL++D+ A K Sbjct: 365 AHYGISEGLVRLSVGLEDIDDLLADVQQALK 395 >5TSU-A nrPDB Length = 422 Score = 519 bits (1337), Expect = e-147, Method: Composition-based stats. Identities = 148/362 (40%), Positives = 230/362 (63%), Gaps = 4/362 (1%) Query: 87 VSTLLVNLDNKFDPF--DAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAK 144 +T +++ + + A+ P+ + TFKQ + ++ ++Y+RSGNPTR+ LE +A Sbjct: 35 FATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFNYSRSGNPTRNCLEKAVAA 94 Query: 145 LDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT 204 LD A F SG+AA +THL+K G++I+ DDVYGG++ QV G+ + V+ Sbjct: 95 LDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNLYFRQVASEFGLKISFVDC 154 Query: 205 TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQG-ALVLVDNSIMSPVLSR 263 +K+ + AAI P+TKLVW+E+PTNP Q++ DI + + H G +++VDN+ MSP R Sbjct: 155 SKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQR 214 Query: 264 PLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLR 323 PL LGADI M+SATK++ GHSDV+ G+++V E L + FLQNS G+ +P DC+LC R Sbjct: 215 PLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 274 Query: 324 GIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF- 382 G+KT+ +R+EK +N +A +L S+P V+KV Y GLP HP H L Q G + +F Sbjct: 275 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFY 334 Query: 383 ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRIS 442 I G++ ++ ++ K F++AVS G +SL +P M+HAS+ R+ G+++ L+R+S Sbjct: 335 IKGTLQHAEIFLKNLKLFTLAVSLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLS 394 Query: 443 AG 444 G Sbjct: 395 VG 396 >3AEO-A nrPDB Length = 389 Score = 510 bits (1313), Expect = e-145, Method: Composition-based stats. Identities = 141/365 (38%), Positives = 221/365 (60%), Gaps = 9/365 (2%) Query: 107 PLYQTATFKQPSAIENG--------PYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGM 158 P++QT+TF S + + Y+R GNPT + E ++ ++ A + F SGM Sbjct: 25 PIFQTSTFCFDSTQQGADLFMGKGEGHIYSRLGNPTVEQFEEMVCSIEGAAGSAAFGSGM 84 Query: 159 AALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQ 217 A+S+ ++ G+ ++AGD +YG + L + +PR G+ V ++T+ +++V AA P Sbjct: 85 GAISSSTLAFLQKGDHLIAGDTLYGCTVSLFTHWLPRFGIEVDLIDTSDVEKVKAAWKPN 144 Query: 218 TKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSAT 277 TK+V+LESP NP ++SDI+ I+ + H +GA ++VD + SP +PLELGADI +HS + Sbjct: 145 TKMVYLESPANPTCKVSDIKGIAVVCHERGARLVVDATFTSPCFLKPLELGADIALHSVS 204 Query: 278 KFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQE 337 K+I GH DV+ GV + K + + F + GS +AP D +LC RG+KT+ +R++ E Sbjct: 205 KYINGHGDVIGGVSSAKTAEDIATIKFYRKDAGSLMAPMDAFLCARGMKTLPIRMQIHME 264 Query: 338 NARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETT 397 N K+A +L H ++ KV + GL PGH + Q G GS F F S +K L+E Sbjct: 265 NGLKVAKFLEQHEKIVKVNHPGLESFPGHDIAKKQMTGYGSTFLFEMKSFEAAKKLMEHL 324 Query: 398 KYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDI 457 K ++AVS G V +LI P M+HA++P + +G+T +LVRIS GIE+VDD+I+DL Sbjct: 325 KVCTLAVSLGCVDTLIEHPASMTHAAVPENIMRKQGITPELVRISVGIENVDDIIADLKQ 384 Query: 458 AFKTF 462 A + + Sbjct: 385 ALELW 389 >1N8P-A nrPDB Length = 393 Score = 499 bits (1285), Expect = e-141, Method: Composition-based stats. Identities = 151/389 (38%), Positives = 227/389 (58%), Gaps = 10/389 (2%) Query: 81 IKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPS-AIENGPYDYTRSGNPTRDALE 139 ++E +T ++ D ++ P+ + TFKQ S A G Y+Y+RS NP R+ LE Sbjct: 2 LQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLE 61 Query: 140 SLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVV 199 +A L+ A F+SG A + + + G V+ DVYGG+ R ++V GV Sbjct: 62 RAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVET 121 Query: 200 KRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ----GALVLVDNS 255 N L+++ I TKLVW+E+PTNP +++DI+K++++ +++VDN+ Sbjct: 122 SFTNDL-LNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNT 180 Query: 256 IMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAP 315 +SP +S PL GADIV+HSATK+I GHSDV+ GVLA + L + + FLQN+ G+ +P Sbjct: 181 FLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSP 240 Query: 316 FDCWLCLRGIKTMALRIEKQQENARKIAMYLSS-HPRVKKVYYAGLPDHPGHHLHFSQAK 374 FD WL RG+KT+ LR+ + +A KIA +L++ V V Y GL HP + + Q + Sbjct: 241 FDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHR 300 Query: 375 GA--GSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREA 431 A G + SF I G + +T+ F++A S G ++SL+ +P M+H IP E REA Sbjct: 301 DALGGGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREA 360 Query: 432 RGLTEDLVRISAGIEDVDDLISDLDIAFK 460 G+ +DLVRIS GIED DDL+ D+ A K Sbjct: 361 SGVFDDLVRISVGIEDTDDLLEDIKQALK 389 >1CS1-A nrPDB Length = 386 Score = 497 bits (1281), Expect = e-141, Method: Composition-based stats. Identities = 146/376 (38%), Positives = 221/376 (58%), Gaps = 3/376 (0%) Query: 88 STLLVNLD-NKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLD 146 +T+ V N + + + P++ ++T+ E +DY+R GNPTRD ++ LA+L+ Sbjct: 6 ATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELE 65 Query: 147 KADRAFCFTSGMAALSAVTH-LIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT 205 A +GM+A+ VT +K G+ +VA D YGGS RL + R V V+ Sbjct: 66 GGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQG 125 Query: 206 KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPL 265 + AA+ + KLV +ESP+NP ++ DI KI +A GA+ +VDN+ +SP L PL Sbjct: 126 DEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVGAVSVVDNTFLSPALQNPL 185 Query: 266 ELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGI 325 LGAD+V+HS TK++ GHSDV+AGV+ K + E+ + N+ G FD +L LRG+ Sbjct: 186 ALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGL 245 Query: 326 KTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-IT 384 +T+ R+E Q NA+ I YL + P VKK+Y+ LP++ GH + Q KG G++ SF + Sbjct: 246 RTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELD 305 Query: 385 GSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAG 444 G + + F++A S G V+SLIS M+HA + E R A G++E L+RIS G Sbjct: 306 GDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTG 365 Query: 445 IEDVDDLISDLDIAFK 460 IED +DLI+DL+ F+ Sbjct: 366 IEDGEDLIADLENGFR 381 >3QI6-A nrPDB Length = 392 Score = 496 bits (1276), Expect = e-140, Method: Composition-based stats. Identities = 160/379 (42%), Positives = 226/379 (59%), Gaps = 7/379 (1%) Query: 85 ASVSTLLVNLDNKFDP-FDAMSTPLYQTATFKQPSAIE-NGPYDYTRSGNPTRDALESLL 142 A ++T ++ + DP A++ P+Y ++TF Q G Y+Y R+GNPTR ALE+ L Sbjct: 16 AGLATRAIHSGYRPDPATGAVNAPIYASSTFAQDGVGGLRGGYEYARTGNPTRTALEAAL 75 Query: 143 AKLDKADRAFCFTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKR 201 A ++ A F+SGMAA A+ +++ G+ +V DD YGG+ RL+ +V V Sbjct: 76 AAVEDAAFGRAFSSGMAAADCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTGWNVEYTP 135 Query: 202 VNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVL 261 V LD V AAI P T+L+W+E+PTNP I+DI I+++ A VLVDN+ SP L Sbjct: 136 VALADLDAVRAAIRPTTRLIWVETPTNPLLSIADIAGIAQLGADSSAKVLVDNTFASPAL 195 Query: 262 SRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLC 321 +PL LGAD+V+HS TK+I GHSDV+ G L E+L + FLQN G+ PFD +L Sbjct: 196 QQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAGAVPGPFDAYLT 255 Query: 322 LRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFS 381 +RG+KT+ LR+++ ENA +A +L+ HP + V Y GLP HPGH + Q +G G + S Sbjct: 256 MRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAARQMRGFGGMVS 315 Query: 382 F-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVR 440 + ++ L T F +A S GSV+SLI P M+HAS E + +DLVR Sbjct: 316 VRMRAGRTAAEQLCAKTNIFILAESLGSVESLIEHPSAMTHASTAGSQLE---VPDDLVR 372 Query: 441 ISAGIEDVDDLISDLDIAF 459 +S GIEDV DL+ DL A Sbjct: 373 LSVGIEDVADLLDDLKQAL 391 >1PFF-A nrPDB Length = 331 Score = 478 bits (1231), Expect = e-135, Method: Composition-based stats. Identities = 129/330 (39%), Positives = 201/330 (60%), Gaps = 3/330 (0%) Query: 136 DALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPR 194 ALE +AKL+ A+ SGM A++A V +K G+ +++ D +YG + L + + Sbjct: 1 SALEGKIAKLEHAEACAATASGMGAIAASVWTFLKAGDHLISDDCLYGCTHALFEHQLRK 60 Query: 195 SGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ-GALVLVD 253 GV V ++ + + P T++V+ E+P NP ++ DI + A Q LV+VD Sbjct: 61 FGVEVDFIDMAVPGNIEKHLKPNTRIVYFETPANPTLKVIDIEDAVKQARKQKDILVIVD 120 Query: 254 NSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK-EVYFLQNSEGSG 312 N+ SP+L+ PL+LG DIV+HSATK+I GH+DV+AG++ + + +AK + +++ G+ Sbjct: 121 NTFASPILTNPLDLGVDIVVHSATKYINGHTDVVAGLVCSRADIIAKVKSQGIKDITGAI 180 Query: 313 LAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQ 372 ++P D WL RG T+ +R+++ ENA+K+A +L H VKKVYY GLPDHPGH + Q Sbjct: 181 ISPHDAWLITRGTLTLDMRVKRAAENAQKVAEFLHEHKAVKKVYYPGLPDHPGHEIAKKQ 240 Query: 373 AKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREAR 432 K GS+ +F + +K +++ S+AVS G +SLI P M+HA +P E REA Sbjct: 241 MKMFGSMIAFDVDGLEKAKKVLDNCHVVSLAVSLGGPESLIQHPASMTHAGVPKEEREAA 300 Query: 433 GLTEDLVRISAGIEDVDDLISDLDIAFKTF 462 GLT++L+R+S G E+V D+I DL A Sbjct: 301 GLTDNLIRLSVGCENVQDIIDDLKQALDLV 330 >4U1T-A nrPDB Length = 389 Score = 460 bits (1183), Expect = e-130, Method: Composition-based stats. Identities = 142/379 (37%), Positives = 214/379 (56%), Gaps = 7/379 (1%) Query: 85 ASVSTLLVNLDNKFDP-FDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLA 143 T LV+ + + P++ + T+++ A + Y Y R NPTR+ LE LA Sbjct: 4 MRFDTRLVHGGRRPSAGTGDVVPPIHVSTTYER-RAQDEPRYFYGRGENPTREELEECLA 62 Query: 144 KLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVN 203 L++A A F+SG AA + + L++ G+ +V+ DDVY G+D L + R GV V+ + Sbjct: 63 GLERAPFATVFSSGQAAAATLLSLVRPGQCVVSTDDVYAGTDGLFD-LAARQGVRVRYAD 121 Query: 204 TTKLDEVAAAIG-PQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLS 262 T + +AAA+ P LVW+E+PTNP + D+ ++S AH +GA V+VDN+ SPVL Sbjct: 122 LTTPEGIAAALAEPDLALVWIETPTNPLLTVVDVAEVSRRAHERGARVVVDNTFASPVLQ 181 Query: 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCL 322 +PL LGAD+ ++S TK IAGH+DV+ G L + L V + + G+ DC+L Sbjct: 182 QPLALGADVSLYSTTKSIAGHADVLGGALVYRDADLHAAVRAYRTTAGNVPGALDCFLVR 241 Query: 323 RGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF 382 RG+ T++LR+ +Q AR + L + P V V+Y GLP+HP H + +Q G++ SF Sbjct: 242 RGLHTLSLRVHRQVATARVLVERLRASPVVGAVHYPGLPEHPQHAVVKAQMSAPGAIVSF 301 Query: 383 I-TGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRI 441 G ++ L++ F+ VS G V SL+ P M+H + AE R RG+ E L+R+ Sbjct: 302 DYLGG--PAERLLDRFTLFTCGVSLGGVHSLVECPALMTHRPLSAEARARRGIGESLIRL 359 Query: 442 SAGIEDVDDLISDLDIAFK 460 S GIED DL DL A Sbjct: 360 SVGIEDPQDLAEDLSRALA 378 >1I43-A nrPDB Length = 445 Score = 457 bits (1175), Expect = e-129, Method: Composition-based stats. Identities = 134/417 (32%), Positives = 219/417 (52%), Gaps = 16/417 (3%) Query: 61 VDGQTHSTVNNTTDSLNTMNIKE-EASVSTLLVNLDNKFD---PFDAMSTPLYQTAT--F 114 V+ +T + N DSL +M S ++ ++ + DA++TP+ T+ F Sbjct: 30 VENETCNDQNVQFDSLPSMKYASFLNSDGSVAIHAGERLGRGIVTDAITTPVVNTSAYFF 89 Query: 115 KQPSAI------ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSA-VTHL 167 + S + ++Y R GNPT LE ++ L+ A+ SGM A + + L Sbjct: 90 NKTSELIDFKEKRRASFEYGRYGNPTTVVLEEKISALEGAESTLLMASGMCASTVMLLAL 149 Query: 168 IKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQ-TKLVWLESP 226 + G IV D Y + + ++P+ G+ ++ + + A+ + L + ESP Sbjct: 150 VPAGGHIVTTTDCYRKTRIFIETILPKMGITATVIDPADVGALELALNQKKVNLFFTESP 209 Query: 227 TNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDV 286 TNP + DI +S++ H +GALV +D + +P+ + L LGAD+V+HSATKF+ GH+DV Sbjct: 210 TNPFLRCVDIELVSKLCHEKGALVCIDGTFATPLNQKALALGADLVLHSATKFLGGHNDV 269 Query: 287 MAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYL 346 +AG ++ KL E+ L + G L P +L +RG+KT+ LR+++Q A ++A L Sbjct: 270 LAGCIS-GPLKLVSEIRNLHHILGGALNPNAAYLIIRGMKTLHLRVQQQNSTALRMAEIL 328 Query: 347 SSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVS 405 +HP+V+ VYY GL HP HH+ Q G G SF + G + + V+ K IA S Sbjct: 329 EAHPKVRHVYYPGLQSHPEHHIAKKQMTGFGGAVSFEVDGDLLTTAKFVDALKIPYIAPS 388 Query: 406 FGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTF 462 FG +S++ P MS+ + R G+ ++LVR S G+ED DDL +D+ A + Sbjct: 389 FGGCESIVDQPAIMSYWDLSQSDRAKYGIMDNLVRFSFGVEDFDDLKADILQALDSI 445 >4OC9-A nrPDB Length = 424 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 118/427 (27%), Positives = 209/427 (48%), Gaps = 48/427 (11%) Query: 79 MNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPS--------AIENGPYDYTRS 130 MN +E TL ++ FD ++S P+YQ + + ++ Y+R Sbjct: 2 MNFNKE----TLALHGAYNFDTQRSISVPIYQNTAYNFENLDQAAARFNLQELGNIYSRL 57 Query: 131 GNPTRDALESLLAKLDKADRAFCFTSGMAA-LSAVTHLIKNGEEIVAGDDVYGGSDRLLS 189 NPT D L LA ++ SGMAA A+ +L +G+ + + +YGG+ L+S Sbjct: 58 SNPTSDVLGQRLANVEGGAFGIPVASGMAACFYALINLASSGDNVAYSNKIYGGTQTLIS 117 Query: 190 QVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGAL 249 + G+ + + LD + I TK ++ ES +NP+ I+DI KI+++A + Sbjct: 118 HTLKNFGIEAREFDIDDLDSLEKVIDQNTKAIFFESLSNPQIAIADIEKINQIAKKHKIV 177 Query: 250 VLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEK------------ 297 + DN++ +P L +P + G D+++HS +K+++G + G L + + Sbjct: 178 SICDNTVATPFLLQPFKHGVDVIVHSLSKYVSGQGTALGGALIERKDLNDLLKNNDRYKA 237 Query: 298 ---------------LAKEVYFLQ------NSEGSGLAPFDCWLCLRGIKTMALRIEKQQ 336 L ++ ++ G+ LAP + WL L+G++T+A+RIEK Sbjct: 238 FNTPDPSYHGLNLNTLDLPIFSIRVIITWLRDLGASLAPQNAWLLLQGLETLAVRIEKHS 297 Query: 337 ENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQA--KGAGSVFSFITGSVALSKHLV 394 +NA K+A +L+SHP +K V Y L + H+L A + SF ++ + Sbjct: 298 QNAEKVANFLNSHPDIKGVNYPTLASNAYHNLFKKYFDKNFASGLLSFEAKDYEHARRIC 357 Query: 395 ETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISD 454 + T+ F +A + G KSLI P +H+ + E + G+T+ +R+S G+E+ DDLI+D Sbjct: 358 DKTQLFLLAANLGDSKSLIIHPASTTHSQLSEEELQKAGITKATIRLSIGLENSDDLIAD 417 Query: 455 LDIAFKT 461 L A ++ Sbjct: 418 LKQAIES 424 >3NDN-A nrPDB Length = 414 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 122/359 (33%), Positives = 200/359 (55%), Gaps = 7/359 (1%) Query: 108 LYQTATFKQPS-AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAAL-SAVT 165 +Y +A + S A E Y Y+R GNPT E L ++ A AF SGMAA+ +++ Sbjct: 55 VYGSAAVAEKSFAGELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMAAVFTSLG 114 Query: 166 HLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLES 225 L+ G+ +VA ++G + S+++PR GV V+ L + A+ T+ V+ E+ Sbjct: 115 ALLGAGDRLVAARSLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFET 174 Query: 226 PTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSD 285 P+NP Q + DI ++E+AHA GA V++DN +P+L + LG D+V++S TK I G Sbjct: 175 PSNPMQSLVDIAAVTELAHAAGAKVVLDNVFATPLLQQGFPLGVDVVVYSGTKHIDGQGR 234 Query: 286 VMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMY 345 V+ G + E + V L G ++ F+ W+ L+G++T+A+R++ +A++IA + Sbjct: 235 VLGGAILGDREYIDGPVQKLMRHTGPAMSAFNAWVLLKGLETLAIRVQHSNASAQRIAEF 294 Query: 346 LSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGS-----VALSKHLVETTKYF 400 L+ HP V+ V Y LP HP + L Q G G+V +F + +++ + Sbjct: 295 LNGHPSVRWVRYPYLPSHPQYDLAKRQMSGGGTVVTFALDCPEDVAKQRAFEVLDKMRLI 354 Query: 401 SIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 I+ + G KSL++ P +H ++ E R A GL + +VRIS G+ED DDLI+D+D A Sbjct: 355 DISNNLGDAKSLVTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRAL 413 >2CTZ-A nrPDB Length = 421 Score = 447 bits (1151), Expect = e-126, Method: Composition-based stats. Identities = 121/421 (28%), Positives = 197/421 (46%), Gaps = 45/421 (10%) Query: 85 ASVSTLLVNLDNKFDPFD-AMSTPLYQTATFKQPS--------AIENGPYDYTRSGNPTR 135 TL ++ + +P + P+Y T ++ S A++ Y+R NPT Sbjct: 1 MRFETLQLHAGYEPEPTTLSRQVPIYPTTSYVFKSPEHAANLFALKEFGNIYSRIMNPTV 60 Query: 136 DALESLLAKLDKADRAFCFTSGMAA-LSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPR 194 D LE LA L+ A SG AA A+T L + G+ IV+ ++YGG+ + R Sbjct: 61 DVLEKRLAALEGGKAALATASGHAAQFLALTTLAQAGDNIVSTPNLYGGTFNQFKVTLKR 120 Query: 195 SGVVVKRVNTTK-LDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD 253 G+ V+ + + +E A +T+ W+ES NP I D+ +++ A +G ++VD Sbjct: 121 LGIEVRFTSREERPEEFLALTDEKTRAWWVESIGNPALNIPDLEALAQAAREKGVALIVD 180 Query: 254 NSI-MSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGE---------------- 296 N+ M L RPL GA +V HS TK++ GH V+AG + G Sbjct: 181 NTFGMGGYLLRPLAWGAALVTHSLTKWVGGHGAVIAGAIVDGGNFPWEGGRYPLLTEPQP 240 Query: 297 --------KLAKEVYFLQ-------NSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARK 341 + E+ F+ +G L PF+ W+ L G++T++LR E+ EN Sbjct: 241 GYHGLRLTEAFGELAFIVKARVDGLRDQGQALGPFEAWVVLLGMETLSLRAERHVENTLH 300 Query: 342 IAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKG-AGSVFSF-ITGSVALSKHLVETTKY 399 +A +L P+V V Y GLP HP H KG G+V +F + G +K + K Sbjct: 301 LAHWLLEQPQVAWVNYPGLPHHPHHDRAQKYFKGKPGAVLTFGLKGGYEAAKRFISRLKL 360 Query: 400 FSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 S + G ++L P +H+ + E + G++ ++VR+S G+E V+DL ++L A Sbjct: 361 ISHLANVGDTRTLAIHPASTTHSQLSPEEQAQAGVSPEMVRLSVGLEHVEDLKAELKEAL 420 Query: 460 K 460 Sbjct: 421 A 421 >4KAM-A nrPDB Length = 453 Score = 447 bits (1150), Expect = e-126, Method: Composition-based stats. Identities = 138/437 (31%), Positives = 219/437 (50%), Gaps = 47/437 (10%) Query: 67 STVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDP-FDAMSTPLYQTATFKQPS------- 118 S N +TD+ T + S T ++ + D +A + P+YQT ++ + Sbjct: 6 SAENTSTDADPTAHW----SFETKQIHAGQQPDSATNARALPIYQTTSYTFENTAHAAAL 61 Query: 119 -AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAA-LSAVTHLIKNGEEIVA 176 +E YTR GNPT D +E +A L+ A +SG AA A+ +L G+ IV+ Sbjct: 62 FGLEVPGNIYTRLGNPTTDVVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVS 121 Query: 177 GDDVYGGSDRLLSQVVPRSGVVVKRVNTTK-LDEVAAAIGPQTKLVWLESPTNPRQQISD 235 +YGG+ L + + G+ V V+ LD AA+ P TK + E+ +NP+ + D Sbjct: 122 SPRLYGGTYNLFHYSLAKLGIEVSFVDDPDNLDSWQAAVRPNTKAFFGETISNPQIDLLD 181 Query: 236 IRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKG 295 ++E+AH G ++VDN+I +P L RP GADIV+HSATK++ GH +AGV+ G Sbjct: 182 TPGVAEVAHRNGIPLIVDNTIATPYLIRPFTQGADIVVHSATKYLGGHGAAIAGVIVDGG 241 Query: 296 ------------------------EKLAKEVYFLQ------NSEGSGLAPFDCWLCLRGI 325 +L Y L+ GS +PF+ +L +G+ Sbjct: 242 TFDWTQGRFPEFTTPDPSYHGVVFAELGAPAYALKARVQLLRDLGSAASPFNAFLVAQGL 301 Query: 326 KTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFS-QAKGAGSVFSF-I 383 +T++LRIE+ NA+++A +L+ V V YAGLP P H KG G+V SF + Sbjct: 302 ETLSLRIERHVSNAQRVAEFLADREDVVTVNYAGLPGSPWHERAKKLSPKGTGAVLSFEL 361 Query: 384 TGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISA 443 G V K V K S + G V+SL+ P +HA + + + G++ LVR++ Sbjct: 362 AGGVEAGKAFVNALKLHSHVANIGDVRSLVIHPASTTHAQLSPAEQLSTGVSPGLVRLAV 421 Query: 444 GIEDVDDLISDLDIAFK 460 GIE ++D+++DL++ F Sbjct: 422 GIEGIEDILADLELGFA 438 >3RI6-A nrPDB Length = 430 Score = 417 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 123/404 (30%), Positives = 203/404 (50%), Gaps = 30/404 (7%) Query: 86 SVSTLLVNLDN-KFDPFDAMSTPLYQTATFKQPSAIENG--------PYDYTRSGNPTRD 136 +T +++ K D A+ TP+Y A F+ ++ E + Y+RS NPT + Sbjct: 26 GFTTRALHVPKAKRDVHGALRTPVYDNAAFEFENSDEIAQVSLGRALGHVYSRSSNPTVE 85 Query: 137 ALESLLAKLDKADRAFCFTSGMAAL-SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRS 195 LE L L A SGMAA+ +A+ L + G+ +V D ++G + L + +P Sbjct: 86 DLEQRLKNLTGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLFQKTLPSF 145 Query: 196 GVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS 255 G+ V+ V+ V A TKL++LE+ +NP+ Q++D+ +S++ HA+G ++VD + Sbjct: 146 GIEVRFVDVMDSLAVEHACDETTKLLFLETISNPQLQVADLEALSKVVHAKGIPLVVDTT 205 Query: 256 IMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKG-------------------- 295 + P L LG DI + S+TKFI+G + GVL G Sbjct: 206 MTPPYLLEAKRLGVDIEVLSSTKFISGGGTSVGGVLIDHGLFEWKSLPSLAPYYAKAGPM 265 Query: 296 EKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKV 355 L K + + G L+P + +L G++TMALRIE+ +NA+++A +L S P+VK V Sbjct: 266 AFLYKARKEVFQNLGPSLSPHNAYLQSLGLETMALRIERSCQNAQELAHWLLSIPQVKCV 325 Query: 356 YYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISM 415 + LPD P + + Q + AGS+ +F S S ++ K A + KSLI Sbjct: 326 NHPSLPDSPFYAIAKRQFRYAGSILTFELESKEASYRFMDALKLIRRATNIHDNKSLILS 385 Query: 416 PCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459 P + +A E R ++ ++R+S GIE+++DL D+ A Sbjct: 386 PYHVIYALNSHEERLKLEISPAMMRLSVGIEEIEDLKEDILQAL 429 >2CB1-A nrPDB Length = 412 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 118/414 (28%), Positives = 191/414 (46%), Gaps = 38/414 (9%) Query: 85 ASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENG-------PYDYTRSGNPTRDA 137 +TL V DP A+ P+Y A + + E Y Y R +PT A Sbjct: 1 MEYTTLAVLAGLPEDPHGAVGLPIYAVAAYGFKTLEEGQERFATGEGYVYARQKDPTAKA 60 Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHLI-KNGEEIVAGDDVYGGSDRLLSQVVPRSG 196 LE L L+ A A SG AA A + + G+E+VA ++G + L QV+ G Sbjct: 61 LEERLKALEGALEAVVLASGQAATFAALLALLRPGDEVVAAKGLFGQTIGLFGQVLSLMG 120 Query: 197 VVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSI 256 V V+ V+ + V A+ +T+ V++E+ NP + D+ ++ +A G ++VDN+ Sbjct: 121 VTVRYVDPE-PEAVREALSAKTRAVFVETVANPALLVPDLEALATLAEEAGVALVVDNTF 179 Query: 257 -MSPVLSRPLELGADIVMHSATKFIAGHSDVMAG-VLAVKGEKLAKEVYFLQNSE----- 309 + L RPL GA +V+ S TK+ +GH V+ G VL+ + E FLQ Sbjct: 180 GAAGALCRPLAWGAHVVVESLTKWASGHGSVLGGAVLSRETELWRNYPQFLQPDLKGQIP 239 Query: 310 ---------------------GSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSS 348 G L+PF+ +L +G++T+ALR+ + E AR +A L Sbjct: 240 WEALRARCFPERVRTLGLSLCGMALSPFNAYLLFQGLETVALRVARMSETARFLAERLQG 299 Query: 349 HPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGS 408 HP+VK + Y GLP+ P H G + + G + + + + A + G Sbjct: 300 HPKVKALRYPGLPEDPAHRNARKYLASGGPILTLDLGDLERASRFLGAIRLLK-AANLGD 358 Query: 409 VKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFKTF 462 ++L+ P +H+ + E R G+T LVR+S G+ED DL++ + A + Sbjct: 359 ARTLLVHPWTTTHSRLKEEARLQAGVTPGLVRVSVGLEDPLDLLALFEEALEAV 412 >5IJG-A nrPDB Length = 427 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 121/401 (30%), Positives = 205/401 (51%), Gaps = 36/401 (8%) Query: 87 VSTLLVNLDNKFD-PFDAMSTPLYQTATF------------------KQPSAIENGPYDY 127 T ++N + A+ P++ T+TF K+P A Y Sbjct: 18 PETQMLNYGYDSELSEGAVKPPVFLTSTFVFKTAEDGRDFFDFVSGRKEPPAGVGAGLVY 77 Query: 128 TRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSA-VTHLIKNGEEIVAGDDVYGGSDR 186 +R +P + +E LA + A+ A F+SGM+A++ + ++ G+ I+ +YGG++ Sbjct: 78 SRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIATTLFAFVRPGDVILHSQPLYGGTET 137 Query: 187 LLSQVVPRSGVV-VKRVNTTKLDEVAAAIGP-----QTKLVWLESPTNPRQQISDIRKIS 240 LL++ GV V + + A + ++ +E+P NP I D+ + Sbjct: 138 LLAKTFFNFGVEAVAFADGVHEATIEKAAEEALAKGRVSVILIETPANPTNSIVDVAAVR 197 Query: 241 EMAHAQGA------LVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVK 294 +A A ++ DN+++ PV +PL+ GAD+ ++S TK++ GHSD++AG + Sbjct: 198 RVAEKIEARQGSRPVIACDNTLLGPVFQKPLDHGADLSVYSLTKYVGGHSDLIAGAVL-G 256 Query: 295 GEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKK 354 + + ++V L+ + G+ L P CW+ R ++T+ LR+E+ NAR IA +L +HP+V+K Sbjct: 257 AKSVVRQVKALRGAIGTQLDPHSCWMLGRSLETLGLRMERADSNARAIAEFLRNHPKVEK 316 Query: 355 VYYAGLPDHPGH--HLHFSQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKS 411 ++Y D L Q GAGS FSF I G A + + + +AVS G +S Sbjct: 317 LHYLPFADERSDIAALFKRQCTGAGSTFSFDIKGGQAAAFRFLNALQILKLAVSLGGTES 376 Query: 412 LISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLI 452 L S P M+H+ +P +VRE G+ E +R+S GIE DDLI Sbjct: 377 LASHPAAMTHSGVPVDVRERIGVLESTIRLSIGIEHPDDLI 417 >2FQ6-A nrPDB Length = 415 Score = 375 bits (963), Expect = e-104, Method: Composition-based stats. Identities = 103/401 (25%), Positives = 189/401 (47%), Gaps = 35/401 (8%) Query: 86 SVSTLLVNLDNKFDPF-DAMSTPLYQTATFKQPSAIE---------NGPYDYTRSGNPTR 135 + T LVN A+++ + + ++ S NG Y R G T Sbjct: 25 KLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRANGELFYGRRGTLTH 84 Query: 136 DALESLLAKLDKADRAFCFTSGMAALS-AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPR 194 +L+ + +L+ F G AA++ ++ I+ G+ ++ + Y S S+++ + Sbjct: 85 FSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAYEPSQDFCSKILSK 144 Query: 195 SGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHA--QGALVLV 252 GV + ++ + P TK+V+LESP + ++ D+ I + A++++ Sbjct: 145 LGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVAAVRSVVPDAIIMI 204 Query: 253 DNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKG---EKLAKEVYFLQNSE 309 DN+ + VL + L+ G D+ + +ATK++ GHSD M G E+L + Y + Sbjct: 205 DNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLM---- 260 Query: 310 GSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLH 369 G + ++ RG++T+ +R+ + E++ K+A +L+ HP+V +V + LP GH Sbjct: 261 GQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFW 320 Query: 370 FSQAKGAGSVFSFITGSVALSKHL---VETTKYFSIAVSFGSVKSLISMPCFMSHASIPA 426 G+ +FSF+ ++ L ++ FS+A S+G +SLI A+ P Sbjct: 321 KRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLIL-------ANQPE 373 Query: 427 EVREARGLTE-----DLVRISAGIEDVDDLISDLDIAFKTF 462 + R E L+R+ G+EDVDDLI+DLD F Sbjct: 374 HIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARI 414 >1U08-A nrPDB Length = 386 Score = 118 bits (295), Expect = 7e-27, Method: Composition-based stats. Identities = 61/297 (20%), Positives = 98/297 (32%), Gaps = 56/297 (18%) Query: 90 LLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDAL----ESLLAKL 145 +NL F FD P Y A Y R+A+ E L Sbjct: 31 QAINLSQGFPDFDG---PRYLQERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYGYQ 87 Query: 146 DKADRAFCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVN 203 AD T+G A +A+T L++NG+E++ D Y + + SG +VKR+ Sbjct: 88 PDADSDITVTAGATEALYAAITALVRNGDEVICFDPSYDS----YAPAIALSGGIVKRMA 143 Query: 204 T------TKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEMAHAQGALVLVDN 254 E AA + +T+LV L +P NP + +D + + V+ D Sbjct: 144 LQPPHFRVDWQEFAALLSERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDE 203 Query: 255 SIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEG---- 310 S+ GH+ V+A + + G Sbjct: 204 VYEHINFSQ-----------------QGHASVLAHPQLRERAVAVSSFGKTYHMTGWKVG 246 Query: 311 --SGLAPFDCWL--CLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDH 363 AP + + + T ++ Q +A L + P +Y LPD Sbjct: 247 YCVAPAPISAEIRKVHQYL-TFSVNTPAQ----LALADMLRAEPE----HYLALPDF 294 >1V2E-A nrPDB Length = 381 Score = 71.2 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 32/179 (17%), Positives = 61/179 (34%), Gaps = 24/179 (13%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADR 150 VNL F + P + ++ + Y R+AL A Sbjct: 27 AVNLGQGFP---SNPPPPFLLEAVRR-ALGRQDQYAPPAGLPALREALAEEFAV---EPE 79 Query: 151 AFCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT--- 205 + TSG A + L+ G+E+V + + + +G + V Sbjct: 80 SVVVTSGATEALYVLLQSLVGPGDEVVVLEPFFD----VYLPDAFLAGAKARLVRLDLTP 135 Query: 206 -----KLDEVAAAIGPQTKLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVDNSI 256 L + A+ P+T+ + L +P NP + ++ I+ +A A ++ D Sbjct: 136 EGFRLDLSALEKALTPRTRALLLNTPMNPTGLVFGERELEAIARLARAHDLFLISDEVY 194 >3NYS-A nrPDB Length = 367 Score = 69.2 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 41/210 (19%), Positives = 70/210 (33%), Gaps = 43/210 (20%) Query: 120 IENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAV-THL-IKNGEEIVAG 177 + +G Y P LE LA A +G AL V L + G+E++ Sbjct: 26 LRHGQYILG----PEVTELEDRLADFVGAKYCISCANGTDALQIVQMALGVGPGDEVITP 81 Query: 178 DDVYGGSDRLLSQVVPRSGVVVKRVNTT------KLDEVAAAIGPQTKLVWLESPTNPRQ 231 G + ++ V G V+ + AAI P+TK + P + Sbjct: 82 ----GFTYVATAETVALLGAKPVYVDIDPRTYNLDPQLLEAAITPRTKAII---PVSLYG 134 Query: 232 QISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGA--------DIVMHSATKF---- 279 Q +D I+ +A G V+ D GA ++ + T F Sbjct: 135 QCADFDAINAIASKYGIPVIEDA---------AQSFGASYKGKRSCNLSTVACTSFFPSA 185 Query: 280 -IAGHSDVMAGVLAVKGEKLAKEVYFLQNS 308 + + D G + ++LA + + Sbjct: 186 PLGCYGD--GGAIFTNDDELATAIRQIARH 213 >1M6S-A nrPDB Length = 347 Score = 67.3 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 60/255 (23%), Positives = 96/255 (37%), Gaps = 38/255 (14%) Query: 121 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDD 179 E G Y +PT + LE L A+ + A SG M ++ + G+E++ D Sbjct: 28 EVGDDVYG--EDPTINELERLAAETFGKEAALFVPSGTMGNQVSIMAHTQRGDEVILEAD 85 Query: 180 VYGGSDRLLSQV---VPRSGVVVKRV----NTTKLDEVAAAIG------PQTKLVWLESP 226 S +V SGV+ V D+V AI P+T L+ +E+ Sbjct: 86 ----SHIFWYEVGAMAVLSGVMPHPVPGKNGAMDPDDVRKAIRPRNIHFPRTSLIAIENT 141 Query: 227 TNPR----QQISDIRKISEMAHAQGALVLVDN------SIMSPVLSRPLELGADIVMHSA 276 N + +I++I +A G V +D SI S V + AD VM Sbjct: 142 HNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGVPVKEYAGYADSVMFCL 201 Query: 277 TKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRG---IKTMALRIE 333 +K + G + V + + G G+ L G + M R++ Sbjct: 202 SKGLC----APVGSVVVGDRDFIERARKARKMLGGGMR-QAGVLAAAGIIALTKMVDRLK 256 Query: 334 KQQENARKIAMYLSS 348 + ENAR +A+ L Sbjct: 257 EDHENARFLALKLKE 271 >2O0R-A nrPDB Length = 411 Score = 64.6 bits (156), Expect = 8e-11, Method: Composition-based stats. Identities = 65/282 (23%), Positives = 101/282 (35%), Gaps = 47/282 (16%) Query: 78 TMNIKEEASVSTL--LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTR 135 T E ++++T VNL F D P A + A Y P R Sbjct: 12 TTVFAEMSALATRIGAVNLGQGFPDEDG--PPKMLQAA-QDAIAGGVNQYPPGPGSAPLR 68 Query: 136 DALESLLAKLDKADRA----FCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLS 189 A+ + + D T G A +AV L++ G E++ + Y S Sbjct: 69 RAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDS----YS 124 Query: 190 QVVPRSG---VVVKRVNT-----TKLDEVAAAIGPQTKLVWLESPTNPR---QQISDIRK 238 VV +G V V V D + A+ P+T+ + + SP NP +++ Sbjct: 125 PVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAA 184 Query: 239 ISEMAHAQGALVLVDNSIMSPVLSR----PLELGAD------IVMHSATK---------- 278 I+E+A A +V+ D V PL G D I + SA K Sbjct: 185 IAEIAVAANLVVITDEVYEHLVFDHARHLPLA-GFDGMAERTITISSAAKMFNCTGWKIG 243 Query: 279 FIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWL 320 + G ++++AGV A K Q + L D W+ Sbjct: 244 WACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWV 285 >1YIY-A nrPDB Length = 429 Score = 63.8 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 36/199 (18%), Positives = 73/199 (36%), Gaps = 27/199 (13%) Query: 92 VNLDNKFDPFDAMSTPLYQTATFKQPSAIENG-PYDYTRS-GNP-TRDALESLLAKL--- 145 +NL F + A P Y + + YTR G+P AL L ++L Sbjct: 40 LNLGQGFPDYHA---PKYALNALAAAANSPDPLANQYTRGFGHPRLVQALSKLYSQLVDR 96 Query: 146 ---DKADRAFCFTSGMAALSAVTHLIKNGEEIVAGD---DVY-------GGSDRLLSQVV 192 + + A + + + G+E++ + D Y GG R + Sbjct: 97 TINPMTEVLVTVGAYEALYATIQGHVDEGDEVIIIEPFFDCYEPMVKAAGGIPRFIPLKP 156 Query: 193 PRSGVVVKRVN-TTKLDEVAAAIGPQTKLVWLESPTNPRQQISD---IRKISEMAHAQGA 248 ++G + + +E+ A +TK++ + +P NP ++ D + ++ + Sbjct: 157 NKTGGTISSADWVLDNNELEALFNEKTKMIIINTPHNPLGKVMDRAELEVVANLCKKWNV 216 Query: 249 LVLVDNSIMSPVLSRPLEL 267 L + D ++ P E Sbjct: 217 LCVSDEVYEH-MVFEPFEH 234 >3UWC-A nrPDB Length = 374 Score = 63.4 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 35/187 (18%), Positives = 80/187 (42%), Gaps = 26/187 (13%) Query: 136 DALESLLAKLDKADRAFCFTSGMAALSAVTHLI--KNGEEIVAGDDVYGGSDRLLSQV-- 191 + E A L A A +G AL+ ++ G+E++ ++ ++ V Sbjct: 41 EKFEKRFAALHNAPHAIGVGTGTDALAMSFKMLNIGAGDEVIT------CANTFIASVGA 94 Query: 192 VPRSGVVVKRVNTT-----KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ 246 + ++G V++ +++ AAI +TK + P + I+D+ ++++A Sbjct: 95 IVQAGATPVLVDSENGYVIDPEKIEAAITDKTKAIM---PVHYTGNIADMPALAKIAKKH 151 Query: 247 GALVLVDN--SIMSPVLSRPL-ELG--ADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKE 301 ++ D +I+ + + + G A +H K + SD AGV+ ++ A++ Sbjct: 152 NLHIVEDACQTILGRINDKFVGSWGQFACFSLHPL-KNLNVWSD--AGVIITHSDEYAEK 208 Query: 302 VYFLQNS 308 + +N Sbjct: 209 LRLYRNH 215 >3CAI-A nrPDB Length = 406 Score = 60.0 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 42/184 (22%), Positives = 77/184 (41%), Gaps = 15/184 (8%) Query: 102 DAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKAD-RAFCFTSGMAA 160 D+++T + + F++ A G + R DA +A L AD + A Sbjct: 40 DSVATTV--STAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAV 97 Query: 161 LSAVTHLIKN-----GEEIVAGDDVYGGSDRLLSQVVPRSGVVVKR--VNTTKLD----E 209 L ++ + G E++ + + R G VK V+ + + Sbjct: 98 LLSLLAEASSSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQ 157 Query: 210 VAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPV-LSRPLELG 268 + I T+LV + S + ++D+R ++++ H GALV+VD+S +P L E Sbjct: 158 WESLISKSTRLVAVNSASGTLGGVTDLRAMTKLVHDVGALVVVDHSAAAPYRLLDIRETD 217 Query: 269 ADIV 272 AD+V Sbjct: 218 ADVV 221 >3OP7-A nrPDB Length = 375 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 38/218 (17%), Positives = 81/218 (37%), Gaps = 28/218 (12%) Query: 159 AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT-------KLDEVA 211 A L + LI+ G+ +++ +Y + + L + G V L+++ Sbjct: 93 ANLLVLYSLIEPGDHVIS---LY-PTYQQLYDIPKSLGAEVDLWQIEEENGWLPDLEKLR 148 Query: 212 AAIGPQTKLVWLESPTNPRQQISD---IRKISEMAHAQGALVLVDNSIMS------PVLS 262 I P TK++ + + NP + D + ++ E+A GA +L D S P + Sbjct: 149 QLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEVGAYILSDEVYRSFSELDVPSII 208 Query: 263 RPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCL 322 + G + S T + G + G +A ++ + ++ FD + Sbjct: 209 EVYDKGIAVNSLSKTYSLPG---IRIGWVAAN-HQVTDILRDYRDYTMICAGVFDDLVAQ 264 Query: 323 RGIKTMALRIEKQ----QENARKIAMYLSSHPRVKKVY 356 + +E+ +EN + ++ P V + Sbjct: 265 LALAHYQEILERNRHILEENLAILDQWIEEEPLVSYIR 302 >1J32-A nrPDB Length = 388 Score = 58.4 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 62/162 (38%), Gaps = 15/162 (9%) Query: 105 STPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLL----AKLDKADRAFCFTSG-MA 159 +TP + K Y R+A+ L AD G + Sbjct: 43 NTPKHIVEAAKAALEQGKTRYGPAAGEPRLREAIAQKLQRDNGLCYGADNILVTNGGKQS 102 Query: 160 ALSAVTHLIKNGEEIVAGDD---VYGGSDRLLS--QVVPRSGVVVKRVNTTKLDEVAAAI 214 + + +I+ G+E++ Y +L V+ + V + +++ AI Sbjct: 103 IFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLAEGTPVILPTTVETQF--KVSPEQIRQAI 160 Query: 215 GPQTKLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVD 253 P+TKL+ +P+NP + ++R I+++A G VL D Sbjct: 161 TPKTKLLVFNTPSNPTGMVYTPDEVRAIAQVAVEAGLWVLSD 202 >4WP0-A nrPDB Length = 472 Score = 58.1 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 74/235 (31%), Gaps = 50/235 (21%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGN--PTRDALESLLAKLDKA 148 +VNL F F P + F+ + + YT++ P L S +L Sbjct: 30 VVNLGQGFPDF---PPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 Query: 149 DRA-----FCFTSGMAA-LSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV 202 + G A +A L+ G+E++ + + + +G V Sbjct: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDC----YEPMTMMAGGRPVFV 142 Query: 203 NT-----------------TKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEM 242 + E+A +TK + L +P NP ++ ++ ++ + Sbjct: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 Query: 243 AHAQGALVLVDNSI---------------MSPVLSRPLELGADIVMHSATKFIAG 282 + + D + + R L +G+ SAT + G Sbjct: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 >3FVS-A nrPDB Length = 422 Score = 58.1 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 74/235 (31%), Gaps = 50/235 (21%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGN--PTRDALESLLAKLDKA 148 +VNL F F P + F+ + + YT++ P L S +L Sbjct: 30 VVNLGQGFPDF---PPPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQ 86 Query: 149 DRA-----FCFTSGMAA-LSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV 202 + G A +A L+ G+E++ + + + +G V Sbjct: 87 EIDPLRNVLVTVGGYGALFTAFQALVDEGDEVIIIEPFFDC----YEPMTMMAGGRPVFV 142 Query: 203 NT-----------------TKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEM 242 + E+A +TK + L +P NP ++ ++ ++ + Sbjct: 143 SLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASL 202 Query: 243 AHAQGALVLVDNSI---------------MSPVLSRPLELGADIVMHSATKFIAG 282 + + D + + R L +G+ SAT + G Sbjct: 203 CQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 >4BMK-A nrPDB Length = 442 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 46/233 (19%), Positives = 83/233 (35%), Gaps = 23/233 (9%) Query: 128 TRSGNPT---RDALESLLAKLDKADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDDVYGG 183 +R N T +E L A F++G MA L ++ L GE ++ D + Sbjct: 123 SRMLNGTFHDHMEVEQALRDFYGTTGAIVFSTGYMANLGIISTLAGKGEYVILDADSHAS 182 Query: 184 SDRLLSQVVPRSGVVVKRVNTTKLDE-VAAAIGPQTKLVWLESPTNPRQQISDIRKISEM 242 Q V + + LD+ + KLV LE + I+ ++++ + Sbjct: 183 IYDGCQQGNAEI-VRFRHNSVEDLDKRLGRLPKEPAKLVVLEGVYSMLGDIAPLKEMVAV 241 Query: 243 AHAQGALVLVDNS----IMSP-----VLSRPLELGADIVMHSATKFIAGHSDVMAGVLAV 293 A GA+VLVD + P ++ LE D V+ + + + + G + Sbjct: 242 AKKHGAMVLVDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSASVG----TVGGFVVS 297 Query: 294 KGEKLAKEVYFLQNSEGSGLAP----FDCWLCLRGIKTMALRIEKQQENARKI 342 K + + P +R + T + E+ NAR + Sbjct: 298 NHPKFEAVRLACRPYIFTASLPPSVVATATTSIRKLMTAHEKRERLWSNARAL 350 >2ZJG-A nrPDB Length = 410 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 36/192 (18%), Positives = 71/192 (36%), Gaps = 33/192 (17%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRS-GNPTRDALESLLAKLDKAD 149 +VNL F +S P Y + + I+N YTR G+P AL L+ L Sbjct: 25 VVNLGQGFPD---ISPPSYVKEELSKAAFIDNM-NQYTRGFGHP---ALVKALSCLYGKI 77 Query: 150 R--------AFCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLS---------- 189 G + +++ L+ G+E++ Y + ++ Sbjct: 78 YQRQIDPNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFYDCYEPMVRMAGAVPVFIP 137 Query: 190 -QVVPRSGVVVKRVN-TTKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEMAH 244 + P G+ + T E+ + +TK + L +P NP ++ +++ I+++ Sbjct: 138 LRSKPTDGMKWTSSDWTFDPRELESKFSSKTKAIILNTPHNPLGKVYTRQELQVIADLCV 197 Query: 245 AQGALVLVDNSI 256 L + D Sbjct: 198 KHDTLCISDEVY 209 >1MDZ-A nrPDB Length = 393 Score = 56.9 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 73/199 (36%), Gaps = 27/199 (13%) Query: 133 PTRDALESLLAKLDKADRAFCFTSGMAALS-AVTHL-IKNGEEIVAGDDVYGGSDRLLSQ 190 P LE+ +L A +S A + A+ L I G+E++ + + ++ Sbjct: 39 PKNQELEAAFCRLTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMI-- 96 Query: 191 VVPRSGVVVKRVNTTK------LDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAH 244 G V+ + + + AAI PQTK + P + +D+ I + Sbjct: 97 --VLLGANPVMVDVDRDTLMVTPEHIEAAITPQTKAII---PVHYAGAPADLDAIYALGE 151 Query: 245 AQGALVLVDNSIMSPVLSRPLELGA---DIVMHSATKFIAGHSDVMAGVLAVKGEKLAKE 301 G V+ D + + + +GA I A K I + G++ + A + Sbjct: 152 RYGIPVIEDAAHATGTSYKGRHIGARGTAIFSFHAIKNI---TCAEGGIVVTDNPQFADK 208 Query: 302 VYFLQ-NSEGSGLAPFDCW 319 + L+ + G D W Sbjct: 209 LRSLKFHGLGV-----DAW 222 >3LVM-A nrPDB Length = 423 Score = 56.5 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 80/395 (20%), Positives = 134/395 (33%), Gaps = 83/395 (21%) Query: 100 PFDAMSTPLYQ----TATFKQPSAIENGPYDYT--RSGNPT-------------RDALES 140 + AM P+Y T A + + GNP D + Sbjct: 16 VYRAMKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARN 75 Query: 141 LLAKLDKAD-RAFCFTSGM------AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVP 193 +A L AD R FTSG A A K G+ I+ + Q + Sbjct: 76 QIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQ-LE 134 Query: 194 RSGVVVKRVNTT-----KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGA 248 R G V + L E+ AA+ T LV + N + DI I EM A+G Sbjct: 135 REGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGI 194 Query: 249 LVLVDNSIMSPVLSRPLELG---ADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVY-- 303 + VD + L P++L D++ S K + + + ++ E Sbjct: 195 IYHVDATQSVGKL--PIDLSQLKVDLMSFSGHKIYGPKG--IGALYVRRKPRVRIEAQMH 250 Query: 304 ------FLQNSEGSG---LAPFDCWLCLRGIKTMALRIEKQQENARKIAMYL-SSHPRVK 353 +++ + + + + + MA +E+ R + L + ++ Sbjct: 251 GGGHERGMRSGTLPVHQIVGMGEAYRIAK--EEMATEMER----LRGLRNRLWNGIKDIE 304 Query: 354 KVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLI 413 +VY G +H ++ SF + + L+ K +AVS GS Sbjct: 305 EVYLNGDLEHGAPNILN---------VSF---NYVEGESLIMALK--DLAVSSGS----- 345 Query: 414 SMPCFMSHASIPAEVREARGLTEDL----VRISAG 444 S + P+ V A GL ++L +R S G Sbjct: 346 ---ACTSASLEPSYVLRALGLNDELAHSSIRFSLG 377 >2OGE-A nrPDB Length = 399 Score = 56.5 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 67/189 (35%), Gaps = 25/189 (13%) Query: 133 PTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIK--NGEEIVAGDDVYGGSDRLLSQ 190 P + E+ A + D A SGM AL + G+E++ S ++ Sbjct: 63 PELEGFEAEFAAYCETDHAVGVNSGMDALQLALRGLGIGPGDEVIVP------SHTYIAS 116 Query: 191 VVPRSGVVVKRVNTT--------KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEM 242 + S V V AI P+T+ + P + +D+ + E+ Sbjct: 117 WLAVSATGATPVPVEPHEDHPTLDPLLVEKAITPRTRALL---PVHLYGHPADMDALREL 173 Query: 243 AHAQGALVLVDNSIMSPVLSRPLELGADIVMHSAT----KFIAGHSDVMAGVLAVKGEKL 298 A G ++ D + R +GA + + + K + D G + +L Sbjct: 174 ADRHGLHIVEDAAQAHGARYRGRRIGAGSSVAAFSFYPGKNLGCFGD--GGAVVTGDPEL 231 Query: 299 AKEVYFLQN 307 A+ + L+N Sbjct: 232 AERLRMLRN 240 >5TXT-B nrPDB Length = 491 Score = 55.7 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 13/148 (8%) Query: 133 PTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNG--EEIVAGDDVYGGSDRLLSQ 190 PT + LE+ LA L K + A F+S A AV L+ + ++ D++ + + Sbjct: 102 PTLN-LEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDEL---NHASMIV 157 Query: 191 VVPRSGVVVKRVNTTKLDEVAAAIG--PQ--TKLVWLESPTNPRQQISDIRKISEMAHAQ 246 + + V L+E+ + P+ KL+ ES + ++DI KI ++A Sbjct: 158 GIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKY 217 Query: 247 GALVLVDNSIMSPVLSRPLELGADIVMH 274 GAL +D + GA + H Sbjct: 218 GALTFLDEVHAVGLYG---PHGAGVAEH 242 >5W70-A nrPDB Length = 445 Score = 55.0 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 39/184 (21%), Positives = 71/184 (38%), Gaps = 15/184 (8%) Query: 140 SLLAKLDKADRAFCFTSGMAALSAVTHL--IKNGEEIVAGDDVY--GGSDRLLSQVVPRS 195 A + SG A+L I G+E++ + GS L VP Sbjct: 80 RAFAAYNGVPHCVPAASGTASLMLALEACGIGAGDEVIVPGLSWVASGSTILGVNAVPIF 139 Query: 196 GVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS 255 V + V AAI T+ + + + ++D+ +S +A G ++ D + Sbjct: 140 CDVDPDTLCLSPEAVEAAITEHTRAIVVVHLYS---ALADMDALSAIAERHGLPLIEDCA 196 Query: 256 IMSPVLSRPLELGADIVMHSATKFIAGHSDVM----AGVLAVKGEKLAKEVYFLQNSEGS 311 R +++GA + +A F HS V+ G + + E A+ V L+ ++G Sbjct: 197 QAHGATYRGVKVGA---LATAGTFSMQHSKVLTSGEGGAVITRDEDFARRVEHLR-ADGR 252 Query: 312 GLAP 315 L+ Sbjct: 253 CLSA 256 >2Z61-A nrPDB Length = 370 Score = 55.0 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 46/99 (46%), Gaps = 6/99 (6%) Query: 155 TSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAI 214 S + A++ +I +G+E++ + Y + G + T ++ + A+ Sbjct: 97 GSSLGLFFALSSIIDDGDEVLIQNPCYPC----YKNFIRFLGAKPVFCDFT-VESLEEAL 151 Query: 215 GPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD 253 +TK + + SP+NP ++ D R+I E A+ ++ D Sbjct: 152 SDKTKAIIINSPSNPLGEVID-REIYEFAYENIPYIISD 189 >3B46-A nrPDB Length = 447 Score = 54.6 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 44/263 (16%), Positives = 85/263 (32%), Gaps = 48/263 (18%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIEN-GPYDYTRSGNPTRDALESLLAKL---D 146 L+NL F + S P + ++ I Y TR ++L L + + + Sbjct: 59 LINLGQGFFSY---SPPQFAIKEAQKALDIPMVNQYSPTRGRPSLINSLIKLYSPIYNTE 115 Query: 147 KADRAFCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRS---GVVVKR 201 T+G LS + L+ G+E++ + Q +P G V Sbjct: 116 LKAENVTVTTGANEGILSCLMGLLNAGDEVIVFEP-------FFDQYIPNIELCGGKVVY 168 Query: 202 VN-----------------TTKLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISE 241 V T ++ AI +TK V + +P NP ++ ++ + Sbjct: 169 VPINPPKELDQRNTRGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGN 228 Query: 242 MAHAQGALVLVDNSIMSPVLSRPLELGADIV---------MHSATKFIAGHSDVMAGVLA 292 + +++ D + A + + SA K A + VL+ Sbjct: 229 ICVKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLS 288 Query: 293 VKGEKLAKEVYFLQNSEGSGLAP 315 + E L+ + +P Sbjct: 289 LNAELLSYAAKAHTRICFASPSP 311 >4Q75-A nrPDB Length = 429 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 55/259 (21%), Positives = 100/259 (38%), Gaps = 45/259 (17%) Query: 160 ALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV-----NTTKLDEVAAAI 214 A S +K G+E++ + V ++G V+K V ++++ I Sbjct: 117 AYSWGLSNLKPGDEVILTVAEHHSCIVPWQIVSQKTGAVLKFVTLNEDEVPDINKLRELI 176 Query: 215 GPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSP-VLSRPLELGADIVM 273 P+TKLV + +N I +I AH GA VLVD P ++ +L AD ++ Sbjct: 177 SPKTKLVAVHHVSNVLASSLPIEEIVVWAHDVGAKVLVDACQSVPHMVVDVQKLNADFLV 236 Query: 274 HSATK--------FIAGHSDVMAGV-LAVKGEKLAKEVYFLQNSEGSGLAPFDC------ 318 S+ K F+ G SD++ + + G ++ +V+ ++ + F+ Sbjct: 237 ASSHKMCGPTGIGFLYGKSDLLHSMPPFLGGGEMISDVFLDHSTYAEPPSRFEAGTPAIG 296 Query: 319 ----------WLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHL 368 +L G+ + E + E + + LSS P V+ Y P H Sbjct: 297 EAIALGAAVDYLSGIGMPKIH---EYEVEIGKYLYEKLSSLPDVR--IYGPRPSESVHR- 350 Query: 369 HFSQAKGAGSVFSFITGSV 387 G++ SF + Sbjct: 351 --------GALCSFNVEGL 361 >6HRH-B nrPDB Length = 469 Score = 53.8 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 73/328 (22%), Positives = 119/328 (36%), Gaps = 36/328 (10%) Query: 49 NSFKLNCVMEKSVDG--QTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMST 106 + F + +MEK D + TVN D+ EASV++ V++ D Sbjct: 28 DQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRH 87 Query: 107 PLYQTATFKQPSAIENG-PYDYTRSGNPTRD---ALESLLAKLDKADRAFCFTSGMAAL- 161 P AT Q + +G TR+ + T LE LA+L + D A F+S A Sbjct: 88 PQVLQAT--QETLQRHGVGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVAND 145 Query: 162 SAVTHLIK--NGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQ-- 217 S + L K G EI + G+ + Q + SG D + + Sbjct: 146 STLFTLAKILPGCEIYSD----AGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNP 201 Query: 218 --TKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSP-VLSRPLELGA-DIVM 273 K+V E+ + I + ++ +++H GAL VD SR +G D +M Sbjct: 202 KIPKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIM 261 Query: 274 H-----SATKFIAGHSDVMAGVLAVKGEKLA-----KEVYFLQNSEGSGL--APFDCWLC 321 H S T + + G +A + + + S + + Sbjct: 262 HKIDIISGT--LGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRL 319 Query: 322 LRGIKTMALRIEKQQENARKIAMYLSSH 349 L+G + ALR Q N + + L Sbjct: 320 LKGEEGQALR-RAHQRNVKHMRQLLMDR 346 >3W1J-A nrPDB Length = 392 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 50/224 (22%), Positives = 92/224 (41%), Gaps = 33/224 (14%) Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVY---GGSDRLLSQVVPR 194 +E L +L A+ +F + A+ V + + G+E++ GGS R + ++ + Sbjct: 63 IEKYLNELTGAESSFVVNNNAGAVFLVLNTLAEGKEVIISRGELVEIGGSFR-IPDIMKK 121 Query: 195 SGVVVKRV---NTTKLDEVAAAIGPQTKLVWLESPTNPRQQ----ISDIRKISEMAHAQG 247 SG +++ V N TK+ + AI T L+ +N + + + ++ H G Sbjct: 122 SGAILREVGTTNKTKVSDYEGAINQNTALLMKVHKSNFYMEGFVEEVKLEDLVKLGHKYG 181 Query: 248 ALVLVDN-------------SIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVK 294 D S+ P + LG D+V S K + G AG++ K Sbjct: 182 IPTYYDAGSGLLINLKEFGISVDEPNFRDCISLGIDLVSGSGDKLLGGPQ---AGIIVGK 238 Query: 295 GEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIK-TMALRIEKQQE 337 + L +++ +N L L L G++ T+ L EK+ E Sbjct: 239 -KNLIEKIK--KNPIARALRIDK--LTLSGLEMTLKLYFEKRYE 277 >3W1H-A nrPDB Length = 452 Score = 53.8 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 50/224 (22%), Positives = 92/224 (41%), Gaps = 33/224 (14%) Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVY---GGSDRLLSQVVPR 194 +E L +L A+ +F + A+ V + + G+E++ GGS R + ++ + Sbjct: 123 IEKYLNELTGAESSFVVNNNAGAVFLVLNTLAEGKEVIISRGELVEIGGSFR-IPDIMKK 181 Query: 195 SGVVVKRV---NTTKLDEVAAAIGPQTKLVWLESPTNPRQQ----ISDIRKISEMAHAQG 247 SG +++ V N TK+ + AI T L+ +N + + + ++ H G Sbjct: 182 SGAILREVGTTNKTKVSDYEGAINQNTALLMKVHKSNFYMEGFVEEVKLEDLVKLGHKYG 241 Query: 248 ALVLVDN-------------SIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVK 294 D S+ P + LG D+V S K + G AG++ K Sbjct: 242 IPTYYDAGSGLLINLKEFGISVDEPNFRDCISLGIDLVSGSGDKLLGGPQ---AGIIVGK 298 Query: 295 GEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIK-TMALRIEKQQE 337 + L +++ +N L L L G++ T+ L EK+ E Sbjct: 299 -KNLIEKIK--KNPIARALRIDK--LTLSGLEMTLKLYFEKRYE 337 >2GB3-A nrPDB Length = 409 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 67/181 (37%), Gaps = 20/181 (11%) Query: 149 DRAFCFTSGMAALSAVTHLI-KNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT--- 204 + G A+ +I G+EI+ + Y + +++ GV + V Sbjct: 103 ENVLVTNGGSEAILFSFAVIANPGDEILVLEPFYA-NYNAFAKIA---GVKLIPVTRRME 158 Query: 205 ---TKLDEVAAAIGPQTKLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVDNSIMS 258 + + I +TK + L +P NP + ++R + E+A G ++VD Sbjct: 159 EGFAIPQNLESFINERTKGIVLSNPCNPTGVVYGKDEMRYLVEIAERHGLFLIVDEVYSE 218 Query: 259 ----PVLSRPLELGAD--IVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSG 312 + L + +D +V+ S +K + + ++ E ++ + Q Sbjct: 219 IVFRGEFASALSIESDKVVVIDSVSKKFSACGARVGCLITRNEELISHAMKLAQGRLAPP 278 Query: 313 L 313 L Sbjct: 279 L 279 >5XT5-A nrPDB Length = 419 Score = 53.0 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 5/115 (4%) Query: 150 RAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV-----NT 204 + + M ALS +K G+E+V + + Q V +G +K + T Sbjct: 93 KGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGT 152 Query: 205 TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSP 259 L++V + TK+V + +N ++ I++++++AH GA+++VD + +P Sbjct: 153 ISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTP 207 >1T3I-A nrPDB Length = 420 Score = 52.3 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 51/248 (20%), Positives = 92/248 (37%), Gaps = 56/248 (22%) Query: 115 KQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEI 174 K +A YTR N T A ++ GM + +K G+EI Sbjct: 83 KFINARSPREIVYTR--NATE------------AINLVAYSWGM-------NNLKAGDEI 121 Query: 175 VAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT-----KLDEVAAAIGPQTKLVWLESPTNP 229 + + + V ++G V+K V L+ + +TKLV + +N Sbjct: 122 ITTVMEHHSNLVPWQMVAAKTGAVLKFVQLDEQESFDLEHFKTLLSEKTKLVTVVHISNT 181 Query: 230 RQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLE---LGADIVMHSATK-------- 278 ++ +I+++AH GA VLVD +P PL+ + D ++ S K Sbjct: 182 LGCVNPAEEIAQLAHQAGAKVLVDACQSAPHY--PLDVQLIDCDWLVASGHKMCAPTGIG 239 Query: 279 FIAGHSDVM-AGVLAVKGEKLAKEVYFLQNSEGSGLAPFDC----------------WLC 321 F+ G +++ A G ++ EV+F + G F+ +L Sbjct: 240 FLYGKEEILEAMPPFFGGGEMIAEVFFDHFTTGELPHKFEAGTPAIAEAIALGAAVDYLT 299 Query: 322 LRGIKTMA 329 G++ + Sbjct: 300 DLGMENIH 307 >1O4S-A nrPDB Length = 389 Score = 52.3 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 73/192 (38%), Gaps = 34/192 (17%) Query: 158 MAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSG---VVVKRVN---TTKLDEVA 211 A +A L+ G+E++ V+ + Q++ G VV ++ L+EV Sbjct: 112 QALFNAFMALLDPGDEVIVFSPVW---VSYIPQIILAGGTVNVVETFMSKNFQPSLEEVE 168 Query: 212 AAIGPQTKLVWLESPTNPRQQISD---IRKISEMAHAQGALVLVDNSIMSPVLSRPL--- 265 + +TK V + SP NP + + + +A + ++ D S V + Sbjct: 169 GLLVGKTKAVLINSPNNPTGVVYRREFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSI 228 Query: 266 ---ELGADIVM--------HSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLA 314 G D ++ HS T + G+ + EK+A V +Q+ S + Sbjct: 229 LDVSEGFDRIVYINGFSKSHSMTGWRVGY--------LISSEKVATAVSKIQSHTTSCIN 280 Query: 315 PFDCWLCLRGIK 326 + L+ ++ Sbjct: 281 TVAQYAALKALE 292 >1GC4-A nrPDB Length = 385 Score = 51.9 bits (123), Expect = 7e-07, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 60/177 (33%), Gaps = 20/177 (11%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDK--- 147 LV L FD TP + ++ A Y R+AL + + Sbjct: 33 LVALTAGEPDFD---TPEHVKEAARRALAQGKTKYAPPAGIPELREALAEKFRRENGLSV 89 Query: 148 -ADRAFCFTSGMAALSAVT-HLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT 205 + G AL + ++ G+E++ + V GVVV+ Sbjct: 90 TPEETIVTVGGSQALFNLFQAILDPGDEVIVLSPYW---VSYPEMVRFAGGVVVEVETLP 146 Query: 206 ------KLDEVAAAIGPQTKLVWLESPTNPRQQISD---IRKISEMAHAQGALVLVD 253 + V AI P+TK + + SP NP + + ++ +A ++ D Sbjct: 147 EEGFVPDPERVRRAITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSD 203 >3WGB-A nrPDB Length = 341 Score = 51.1 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 61/256 (23%), Positives = 95/256 (37%), Gaps = 32/256 (12%) Query: 121 ENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDD 179 E G Y +P +ALE+ A L + A SG M+ L AV + GE V G Sbjct: 29 EVGDDVYG--EDPGVNALEAYGADLLGKEAALFVPSGTMSNLLAVMSHCQRGEGAVLGSA 86 Query: 180 VYGGSDRLLSQVVPRSG-VVVKRVNT-----TKLDEVAAAIGPQ------TKLVWLESPT 227 R +Q G V ++ V L +V AAI P T+LV LE+ Sbjct: 87 A--HIYRYEAQGSAVLGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVCLENTH 144 Query: 228 N-PRQQISDIRKISEMAHAQGALVLVDN------SIMSPVLSRPLELGADIVMHSATKFI 280 N + +R++ E+ G + +D + S R L D V +K + Sbjct: 145 NGKVLPLPYLREMRELVDEHGLQLHLDGARLFNAVVASGHTVRELVAPFDSVSICLSKGL 204 Query: 281 AGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMA---LRIEKQQE 337 G L V L+ G G+ L G+ + +R+ Sbjct: 205 G----APVGSLLVGSHAFIARARRLRKMVGGGMR-QAGILAQAGLFALQQHVVRLADDHR 259 Query: 338 NARKIAMYLSSHPRVK 353 AR++A L++ P ++ Sbjct: 260 RARQLAEGLAALPGIR 275 >4MY5-A nrPDB Length = 393 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 43/111 (38%), Gaps = 16/111 (14%) Query: 159 AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT------TKLDEVAA 212 A +++T +++ G++++ Y G VV G V ++T + + Sbjct: 105 ALSASLTAILEPGDKVLLPAPAYPG----YEPVVNLVGAEVVEIDTRSNDFVLTPEMLEE 160 Query: 213 AI---GPQTKLVWLESPTNP---RQQISDIRKISEMAHAQGALVLVDNSIM 257 AI G K V L PTNP I+ ++E+ V+ D Sbjct: 161 AILKEGEALKAVILNYPTNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYA 211 >1GDE-A nrPDB Length = 389 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 32/182 (17%), Positives = 64/182 (35%), Gaps = 23/182 (12%) Query: 91 LVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADR 150 +++L FD TP + K+ Y R+A+ L K + + Sbjct: 28 VISLGIGEPDFD---TPQHIKEYAKEALDKGLTHYGPNIGLLELREAIAEKLKKQNGIEA 84 Query: 151 A------FCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT 204 + A L ++ +K+GEE++ + V +G V T Sbjct: 85 DPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPA----FVSYAPAVILAGGKPVEVPT 140 Query: 205 -------TKLDEVAAAIGPQTKLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVDN 254 +DE+ + +T+ + + SP NP + D+ +I++ +V+ D Sbjct: 141 YEEDEFRLNVDELKKYVTDKTRALIINSPCNPTGAVLTKKDLEEIADFVVEHDLIVISDE 200 Query: 255 SI 256 Sbjct: 201 VY 202 >4W91-A nrPDB Length = 422 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 42/218 (19%), Positives = 73/218 (33%), Gaps = 29/218 (13%) Query: 111 TATFKQPSAIENGPYDYTRSGNPTRDALE------SLLAKLDKADRAFCFTSGMAALSAV 164 T + A + + N DA E D + A++ V Sbjct: 60 THAYANEYANVHRGLHF--LSNAATDAYEKSRETVRRFLNAGSVDEIVFTKNATEAINTV 117 Query: 165 -----THLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTK-----LDEVAAAI 214 I G+EI+ + + + R G + ++E + Sbjct: 118 AYGYGMPFIGEGDEILLSIMEHHSNIVPWHFIRERQGAKLVFTPVDDNGVFHIEEFEKRL 177 Query: 215 GPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMH 274 +TKLV + +N + I+KI E+AHA+G VLVD S + L D+ Sbjct: 178 SERTKLVAITHMSNTLGTVVPIKKIVELAHARGIPVLVDGS------QGAVHLPVDVQDL 231 Query: 275 SATKFI-AGH---SDVMAGVLAVKGEKLAKEVYFLQNS 308 ++ GH GVL ++ +++ Q Sbjct: 232 GCDWYVFTGHKVYGPSGIGVL-YGRAQMLEKMRPFQGG 268 >4M2J-A nrPDB Length = 406 Score = 50.4 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 45/253 (17%), Positives = 89/253 (35%), Gaps = 38/253 (15%) Query: 128 TRSGNPTRDALESLLAKLDKADRAFCF---TSGMAALSAVTHLIKNGEEIVAGDDVY--- 181 ++ G R A+ A D S A + L+ G+ +V + +Y Sbjct: 83 SQGGEGVRRAIADRYA---GGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSL 139 Query: 182 -------GGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNP---RQ 231 G +L R G D +A + P T V + P NP Sbjct: 140 GHYPRAAGCDVAVLPGRAVRDG-------EIDPDVLAGLVTPGTAAVIVNFPHNPTGVTL 192 Query: 232 QISDIRKISEMAHAQGALVLVDNSIMS-----PVLSRPLELGADIVMH-SATKFIAGHSD 285 +R + E A GA+++ D + VL+ P G D V + + +K Sbjct: 193 SPQGLRALKERTAATGAVLVWDAATAEIAHRWEVLADPGADGGDTVSYGTLSKTFGLPGL 252 Query: 286 VMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGI----KTMALRIEKQQENARK 341 + +A ++L + L++ L+P + R + + + R + + N Sbjct: 253 RVGWAVA--PKELLTATFPLRDRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAH 310 Query: 342 IAMYLSSHPRVKK 354 + ++++H + + Sbjct: 311 LTGWMAAHEELVR 323 >3WY7-A nrPDB Length = 404 Score = 48.4 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 44/197 (22%), Positives = 69/197 (35%), Gaps = 12/197 (6%) Query: 120 IENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAA-LSAVTHLIKNGEEIVAGD 178 G +A E LA A+ A F+SG A L A+ L G IV+ Sbjct: 89 GGAGGSRLVTGNTELHEAFEHQLASFLGAESALVFSSGYTANLGALVALSGPGSLIVSDA 148 Query: 179 DVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRK 238 + R V R +AA + +V ES + ++ +R Sbjct: 149 LSHASLVDACRLSRARVVVSPHRDVDAVDAALAARTEER-AVVVTESVFSADGDLAPLRD 207 Query: 239 ISEMAHAQGALVLVD--------NSIMSPVLSRPLELGA-DIVMHSA-TKFIAGHSDVMA 288 + + GAL+LVD + +L GA DIVM + +K + + Sbjct: 208 LHAVCRRHGALLLVDEAHGLGVRGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVL 267 Query: 289 GVLAVKGEKLAKEVYFL 305 G AV+ + F+ Sbjct: 268 GPEAVRAHLIDTARSFI 284 >2AEV-A nrPDB Length = 374 Score = 48.4 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 46/204 (22%), Positives = 81/204 (39%), Gaps = 27/204 (13%) Query: 149 DRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSG--VVVKRVNTTK 206 D+ F +A+ A +K + I ++ G + RS V K + K Sbjct: 77 DKCVGFNRTSSAILATILALKPKKVIHYLPELPGH------PSIERSCKIVNAKYFESDK 130 Query: 207 LDEVAAAIGPQTKLVWLESPTNPRQQISDIR---KISEMAHAQGALVLVDNSIMSP---- 259 + E+ I T ++ + + ++ ++ K+ A + A+V VD+ S Sbjct: 131 VGEILNKIDKDTLVII--TGSTMDLKVIELENFKKVINTAKNKEAIVFVDD--ASGARVR 186 Query: 260 -VLSRP--LELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPF 316 + ++P L+LGAD+V+ S K + G G L ++L ++Y G P Sbjct: 187 LLFNQPPALKLGADLVVTSTDKLMEGPR----GGLLAGKKELVDKIYIEGTKFGLEAQPP 242 Query: 317 DCWLCLRGIKTMAL-RIEKQQENA 339 R +K L RI K E A Sbjct: 243 LLAGIYRALKNFNLERIRKAFERA 266 >2DOU-A nrPDB Length = 376 Score = 47.7 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 38/245 (15%), Positives = 78/245 (31%), Gaps = 45/245 (18%) Query: 127 YTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDR 186 Y +P R+AL L + + L + + ++ + Y Sbjct: 80 YGVGLDPRREAL-----ALIGSQEGLA--------HLLLALTEPEDLLLLPEVAYPSYFG 126 Query: 187 LLSQV-VPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISD---IRKISEM 242 + + ++ L V + + K++ L P NP ++D + + Sbjct: 127 AARVASLRTFLIPLREDGLADLKAVPEGVWREAKVLLLNYPNNPTGAVADWGYFEEALGL 186 Query: 243 AHAQGALVLVDNSIMSPVLSR--------PLEL-GAD---IVMHSATKFIAGHSDVMAGV 290 A G ++ DN P + + PL L GA + + S +K +AG Sbjct: 187 ARKHGLWLIHDN----PYVDQVYEGEAPSPLALPGAKERVVELFSLSKSYN-----LAGF 237 Query: 291 LAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTM-----ALR--IEKQQENARKIA 343 + + L+ +G + G++ + +R +E A +A Sbjct: 238 RLGFALGSEEALARLERVKGVIDFNQYAGVLRMGVEALKTPKEVVRGYARVYRERALGMA 297 Query: 344 MYLSS 348 L Sbjct: 298 EALKG 302 >3BB8-A nrPDB Length = 437 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 53/135 (39%), Gaps = 25/135 (18%) Query: 136 DALESLLAKLDKADRAFCFTSGMAA-LSAVTHL---------IKNGEEIVAGDDVYGGSD 185 DA E L + TSG +A L A+T L +K G+E++ + + Sbjct: 65 DAFEKKLGEYLGVPYVLTTTSGSSANLLALTALTSPKLGVRALKPGDEVITVAAGFPTT- 123 Query: 186 RLLSQVVPRSGVVVKRVNTTKL------DEVAAAIGPQTKLVWL-ESPTNPRQQISDIRK 238 ++ + G++ V+ + AA+ +TK + + + N + D+ + Sbjct: 124 --VNPTIQN-GLIPVFVDVDIPTYNVNASLIEAAVSDKTKAIMIAHTLGN----LFDLAE 176 Query: 239 ISEMAHAQGALVLVD 253 + +A ++ D Sbjct: 177 VRRVADKYNLWLIED 191 >5HH9-A nrPDB Length = 390 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 48/249 (19%), Positives = 93/249 (37%), Gaps = 45/249 (18%) Query: 154 FTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV----------N 203 T G+AA+ L++ G+EI+ + + L R G V+ Sbjct: 85 TTDGLAAIYGGL-LVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSA 143 Query: 204 TTKLDEVAAAIGPQTKLV---WLESPTNPRQQISDIRKIS-----EMAHAQGALVLVDNS 255 L +AA I PQT+++ W++S + + I +I K+ + + +VD Sbjct: 144 DEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGV 203 Query: 256 IMSPVLSRPL-ELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV------YFLQNS 308 V + D + K++ G GV+ + E+L + + + ++ Sbjct: 204 HGFGVEDVSFADFDCDYFIAGTHKWLFGPRGT--GVIIARSEQLQEHLVPSIPTFSRADN 261 Query: 309 EGSGLAP--FDCWLCLRGIKT---MALRI-------EKQQENARKIAMYLSSHPRVKKVY 356 G+ + P + + + T + L++ Q NA + L HP+V+ V Sbjct: 262 FGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNA-YLKQRLGEHPKVRLVT 320 Query: 357 YAGLPDHPG 365 P P Sbjct: 321 ----PTSPE 325 >3PDX-A nrPDB Length = 402 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 35/204 (17%), Positives = 72/204 (35%), Gaps = 20/204 (9%) Query: 65 THSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQP-SAIENG 123 ++ T N ++ M +K + + + +++ F + T T K + + Sbjct: 9 SNKTFNPIRAIVDNMKVKPNPNKTVISLSIG-DPTVFGNLPTDPEVTQAMKDALDSGKYN 67 Query: 124 PYDYTRSGNPTRDALESLL----AKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDD 179 Y + +R+ + S A L+ D A + L G+ I+ Sbjct: 68 GYAPSIGYLSSREEVASYYHCPEAPLEAKDVILTSGCSQAIELCLAVLANPGQNILIPRP 127 Query: 180 VYGGSDRLLSQVVPRSGVVVKRVNTT-------KLDEVAAAIGPQTKLVWLESPTNPRQQ 232 L + G+ VK N L ++ + I +T + + +P+NP Sbjct: 128 ----GFSLYRTLAESMGIEVKLYNLLPEKSWEIDLKQLESLIDEKTACLVVNNPSNPCGS 183 Query: 233 ISD---IRKISEMAHAQGALVLVD 253 + ++KI +A Q +L D Sbjct: 184 VFSKRHLQKILAVAERQCVPILAD 207 >1XI9-A nrPDB Length = 406 Score = 46.5 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 33/189 (17%), Positives = 63/189 (33%), Gaps = 23/189 (12%) Query: 82 KEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYDYTRS-GNPTRDALES 140 +E ++ L+ P + + + AI+ G Y S G P L Sbjct: 31 RELEKKGIKVIRLNIGDPVKFDFQPPEHMKEAYCK--AIKEGHNYYGDSEGLP---ELRK 85 Query: 141 LLAKLDKADRAF--------CFTSGMAALSAVT-HLIKNGEEIVAGDDVYGGSDRLLSQV 191 + + +K + AL + L+ G+EI+ Y L + Sbjct: 86 AIVEREKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILVPGPSY-PPYTGLVKF 144 Query: 192 VPRSGVVVKRVNTTKL----DEVAAAIGPQTKLVWLESPTNPRQQISD---IRKISEMAH 244 V + + D++ I +TK + + +P NP + D + +I +A Sbjct: 145 YGGKPVEYRTIEEEDWQPDIDDIRKKITDRTKAIAVINPNNPTGALYDKKTLEEILNIAG 204 Query: 245 AQGALVLVD 253 V+ D Sbjct: 205 EYEIPVISD 213 >5WMH-A nrPDB Length = 475 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 37/221 (16%), Positives = 77/221 (34%), Gaps = 26/221 (11%) Query: 55 CVMEKSVDGQTHSTVNNTTDSLNTMNIKEEASV------STLL------VNLDNKFDPFD 102 C M K D +T S+ + + S ++K ++ +TL+ + L FD Sbjct: 53 CAMAKPNDAETLSSSVDMSLSPRVQSLKPSKTMVITDLAATLVQSGVPVIRLAAGEPDFD 112 Query: 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDK---ADRAFCFTSG-- 157 TP Y R+A+ L + + A ++G Sbjct: 113 ---TPKVVAEAGINAIREGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGAK 169 Query: 158 MAALSAVTHLIKNGEEIVAGDD---VYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAI 214 + L AV + G+E++ Y RL + ++ + + Sbjct: 170 QSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIPTKISNNFLLDPKDLESKL 229 Query: 215 GPQTKLVWLESPTNPRQQISD---IRKISEMAHAQGALVLV 252 +++L+ L SP+NP + + +I+ + L+++ Sbjct: 230 TEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLLVL 270 >3DYD-A nrPDB Length = 427 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 51/149 (34%), Gaps = 19/149 (12%) Query: 143 AKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV 202 A L+ D A + L G+ I+ L + G+ VK Sbjct: 114 APLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRP----GFSLYKTLAESMGIEVKLY 169 Query: 203 NTT-------KLDEVAAAIGPQTKLVWLESPTNPRQQISD---IRKISEMAHAQGALVLV 252 N L ++ I +T + + +P+NP + ++KI +A Q +L Sbjct: 170 NLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILA 229 Query: 253 DNSIMSPVLS----RPLE-LGADIVMHSA 276 D V S PL L D+ + S Sbjct: 230 DEIYGDMVFSDCKYEPLATLSTDVPILSC 258 >2X8U-A nrPDB Length = 412 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 14/135 (10%) Query: 128 TRSGNPT---RDALESLLAKLDKADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDD---- 179 +R N T A E L + + A F++G A L ++ L G+ I+ D Sbjct: 81 SRVLNGTYQGHKACEDALKEFYGTEHAIVFSTGYQANLGMISTLAGKGDYIILDADSHAS 140 Query: 180 VYGGSDRLLSQVVPRSGVVVKRVNTTKLDE-VAAAIGPQTKLVWLESPTNPRQQISDIRK 238 +Y G +++ V + + LD+ + KLV LE + I+ +++ Sbjct: 141 IYDGCWLGDAEI-----VRFRHNSVEDLDKRLGRLPAEAGKLVVLEGVYSMMGDIAPLQE 195 Query: 239 ISEMAHAQGALVLVD 253 + ++ GA++LVD Sbjct: 196 MVAVSKKHGAMILVD 210 >1B9H-A nrPDB Length = 388 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 45/205 (21%), Positives = 78/205 (38%), Gaps = 25/205 (12%) Query: 119 AIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHL--IKNGEEIVA 176 A+E G + R G ++ E A A A T+G AL + + G E++ Sbjct: 26 ALEQGQWW--RMGGDEVNSFEREFAAHHGAAHALAVTNGTHALELALQVMGVGPGTEVIV 83 Query: 177 GDDVYGGSDRLLSQVVPRSGVVVKRVNTT------KLDEVAAAIGPQTKLVWLESPTNPR 230 + SQ R G V V+ + VAAA+ P+TK++ P + Sbjct: 84 P----AFTFISSSQAAQRLGAVTVPVDVDAATYNLDPEAVAAAVTPRTKVIM---PVHMA 136 Query: 231 QQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELG-----ADIVMHSATKFIAGHSD 285 ++D+ +++++ G +L D + + +G A + AG Sbjct: 137 GLMADMDALAKISADTGVPLLQDAAHAHGARWQGKRVGELDSIATFSFQNGKLMTAGEG- 195 Query: 286 VMAGVLAVKGEKLAKEVYFLQNSEG 310 V+ GE E FL++S G Sbjct: 196 --GAVVFPDGETEKYETAFLRHSCG 218 >5YHV-A nrPDB Length = 394 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 24/156 (15%), Positives = 46/156 (29%), Gaps = 30/156 (19%) Query: 145 LDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT 204 ++ S L A G+ + Y ++ G V + Sbjct: 95 VEPDAVVITTGSSGGFLLAFLACFDAGDRVAMASPGYPC----YRNILSALGCEVVEIPC 150 Query: 205 TK------LDEVAAAIGPQTKLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVDNS 255 ++ A I P + V + SP NP + ++ I+ A ++ D Sbjct: 151 GPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLISDEV 210 Query: 256 IMSPVLSRPLELGA------------DIVMHSATKF 279 V GA +V++S +K+ Sbjct: 211 YHGLVYQ-----GAPQTSCAWQTSRNAVVVNSFSKY 241 >1BW0-A nrPDB Length = 416 Score = 45.3 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 38/122 (31%), Gaps = 16/122 (13%) Query: 152 FCFTSG--MAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT----- 204 SG L A+T + G+ + + V G+ + N Sbjct: 107 VVLCSGGSHGILMAITAICDAGDYALVPQPGFPH----YETVCKAYGIGMHFYNCRPEND 162 Query: 205 --TKLDEVAAAIGPQTKLVWLESPTNP---RQQISDIRKISEMAHAQGALVLVDNSIMSP 259 LDE+ +TKL+ + +P+NP + I +A + D Sbjct: 163 WEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEELRLPLFSDEIYAGM 222 Query: 260 VL 261 V Sbjct: 223 VF 224 >3L8A-A nrPDB Length = 421 Score = 45.3 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 33/170 (19%), Positives = 61/170 (35%), Gaps = 27/170 (15%) Query: 159 AALSAVTHLIKNGEEIVAGDDVY---GGSDRLLSQVVPRSGVVVK--RVNTTKLDEVAAA 213 A A+ + G+ ++ VY + RL + + + + R Sbjct: 131 AISIALQAFSEKGDAVLINSPVYYPFARTIRLNDHRLVENSLQIINGRFEIDFEQLEKDI 190 Query: 214 IGPQTKLVWLESPTNPRQQI---SDIRKISEMAHAQGALVLVD----------NSIMSPV 260 I K+ L SP NP ++ D+ KI+E+ G +++ D N+ S Sbjct: 191 IDNNVKIYLLCSPHNPGGRVWDNDDLIKIAELCKKHGVILVSDEIHQDLALFGNTHHSLN 250 Query: 261 LSRPLELGADIVMHSATKFIAGHSDVMAGV----LAVKGEKLAKEVYFLQ 306 I++ SATK +AG ++ E L ++ + Q Sbjct: 251 TLDASYKDFTIILSSATKTFN-----IAGTKNSFAIIQNESLRRKFQYRQ 295 >3PJ0-A nrPDB Length = 359 Score = 45.3 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 54/277 (19%), Positives = 97/277 (35%), Gaps = 37/277 (13%) Query: 130 SGN-PTRDALESLLAKLDKADRAFCFTSG-MAALSAVTHLI-KNGEEIVAGDDV------ 180 GN + E+ +AK+ A F SG MA A+ + VA + Sbjct: 44 YGNGAVIEDFETKIAKILGKQSAVFFPSGTMAQQIALRIWADRKENRRVAYHPLSHLEIH 103 Query: 181 -YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTN------PRQQI 233 G L G + + + ++ V +E P P + Sbjct: 104 EQDGLKELQQITPLLLGTANQLLTIDDI----KSLREPVSSVLIELPQREIGGQLPAFE- 158 Query: 234 SDIRKISEMAHAQGALVLVDNSIM---SPVLSR-PLELGA--DIVMHSATKFIAGHSDVM 287 ++ KISE H QG + +D + + +P + E+ A D V S K I G + Sbjct: 159 -ELEKISEYCHEQGISLHLDGARLWEITPFYQKSAEEICALFDSVYVSFYKGIGG----I 213 Query: 288 AGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRG--IKTMALRIEKQQENARKIAMY 345 AG + + +E + G L ++ + ++ + E A+ +A Sbjct: 214 AGAILAGNDDFVQEAKIWKRRYGGDLISLYPYILSADYYFEKRIGKMAEYFEAAKGLAER 273 Query: 346 LSSHPRVKKVYYAGLP-DHPGHHLHFSQAKGAGSVFS 381 +S VK V +P + H + A G++ + Sbjct: 274 FNSCSGVKTV--PEVPVSNMFHVYFENSADEIGAILT 308 >2C81-A nrPDB Length = 418 Score = 45.0 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 48/304 (15%), Positives = 96/304 (31%), Gaps = 69/304 (22%) Query: 140 SLLAKLDKADRAFCFTSGMAALSAVTHLIK--NGEEIVAGDDVYGGSDRLLSQVVPRSGV 197 A + TSG AL + G+E++ S ++ V Sbjct: 49 KAFADFNGVPYCVPTTSGSTALMLALEALGIGEGDEVIVP------SLTWIATATAVLNV 102 Query: 198 VV--KRVNTT------KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGAL 249 V+ + +AI +TK + P + ++++ +I+E+A Sbjct: 103 NALPVFVDVEADTYCIDPQLIKSAITDKTKAII---PVHLFGSMANMDEINEIAQEHNLF 159 Query: 250 VLVDNSIMSPVL---SRPLELGADIVMHSATKFIAGHSDVM----AGVLAVKGEKLAKEV 302 V+ D + + R +G DI S V+ G++ K +L + + Sbjct: 160 VIEDCAQSHGSVWNNQRAGTIG-DIGAFSCQ-----QGKVLTAGEGGIIVTKNPRLFELI 213 Query: 303 YFLQ------------------------NSEGS--GLAPFDCWLCLRGIKTMALRIEKQQ 336 L+ + +GS L+ F + L ++ + + ++ Sbjct: 214 QQLRADSRVYCDDSSELMHGDMQLVKKGDIQGSNYCLSEFQSAILLDQLQELDDKNAIRE 273 Query: 337 ENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF--ITGSVALSKHLV 394 +NA + LS +K + P Q G VF F + + Sbjct: 274 KNAMFLNDALSKIDGIKVMKRP-----PQ---VSRQ-TYYGYVFRFDPVKFGGLNADQFC 324 Query: 395 ETTK 398 E + Sbjct: 325 EILR 328 >4PIW-A nrPDB Length = 396 Score = 44.6 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 76/231 (32%), Gaps = 40/231 (17%) Query: 95 DNKFDPFDAMSTPL------YQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKA 148 + PF+A P+ Y + +G + TR LE + Sbjct: 18 GSHMIPFNA--PPVVGTELDYMQSAMGSGKLCGDGGF--TRRCQ---QWLEQRF----GS 66 Query: 149 DRAFCFTSGMAAL--SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT-- 204 + S A+L +A+ I+ G+E++ Y + + G + V+ Sbjct: 67 AKVLLTPSCTASLEMAALLLDIQPGDEVIM--PSY--TFVSTANAFVLRGAKIVFVDVRP 122 Query: 205 ----TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS--IMS 258 + AAI +T+++ P + ++ I +A V+ D + +MS Sbjct: 123 DTMNIDETLIEAAITDKTRVI---VPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMS 179 Query: 259 PVLSRPLELGADI---VMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQ 306 R L I H + AG G + + L + ++ Sbjct: 180 TYKGRALGTIGHIGCFSFHETKNYTAGGE---GGATLINDKALIERAEIIR 227 >2YRI-A nrPDB Length = 353 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 57/153 (37%), Gaps = 30/153 (19%) Query: 137 ALESLLAKL----DKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192 A++ LA L + A A SG + A + G +V + + S R+ +++ Sbjct: 37 AIQERLAALFDPGEGALVAALAGSGSLGMEAGLANLDRGPVLVLVNGAF--SQRV-AEMA 93 Query: 193 PRSGVVVKRVN-----TTKLDEVAAAIGPQ----TKLVWLESPT---NPRQQISDIRKIS 240 G+ + ++ + VA A+ + LV E+ T NP I Sbjct: 94 ALHGLDPEVLDFPPGEPVDPEAVARALKRRRYRMVALVHGETSTGVLNPA------EAIG 147 Query: 241 EMAHAQGALVLVDNSIMSPVLSRPL---ELGAD 270 +A GAL +D +L P +G D Sbjct: 148 ALAKEAGALFFLDAVTTLGML--PFSMRAMGVD 178 >6F35-A nrPDB Length = 410 Score = 43.4 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 49/139 (35%), Gaps = 19/139 (13%) Query: 144 KLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGV----VV 199 + + + +A+ + G+E++ Y S + + V Sbjct: 98 AYELDEITVATGAKQILFNAMMASLDPGDEVIIPTP-YWTSYSDIVHICEGKPVLIACDA 156 Query: 200 KRVNTTKLDEVAAAIGPQTKLVWLESPTNP---RQQISDIRKISE-MAHAQGALVLVDNS 255 +++ AAI P+T+ V L SP+NP +D R + E + +LVD+ Sbjct: 157 SSGFRLTAEKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLEVLLRHPHVWLLVDDM 216 Query: 256 ----------IMSPVLSRP 264 ++P P Sbjct: 217 YEHIVYDGFRFVTPAQLEP 235 >2O1B-A nrPDB Length = 404 Score = 43.4 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 39/225 (17%), Positives = 74/225 (32%), Gaps = 43/225 (19%) Query: 109 YQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLI 168 + FKQ Y R N T D E + L ++ T +I Sbjct: 85 HGKEAFKQAIVD-----FYQRQYNVTLDK-EDEVCILYGTKNGL--------VAVPTCVI 130 Query: 169 KNGEEIVAGDDVYGGSDRLLSQVVPR-----SGVVVKRVNTTKLDEVAAAIGPQTKLVWL 223 G+ ++ D Y +D L ++ + +V + I +TKL++L Sbjct: 131 NPGDYVLLPDPGY--TDYLAGVLLADGKPVPLNLEPPHY-LPDWSKVDSQIIDKTKLIYL 187 Query: 224 ESPTNP-----RQQISDIRKISEMAHAQGALVLVDNSIMSPVL----SRPLEL----GAD 270 P NP +++ D I++ ++ D P L G D Sbjct: 188 TYPNNPTGSTATKEVFD-EAIAKF-KGTDTKIVHD--FAYGAFGFDAKNPSILASENGKD 243 Query: 271 IV--MHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGL 313 + ++S +K + AV + + + + Q +G+ Sbjct: 244 VAIEIYSLSKGYNMSGFRVG--FAVGNKDMIQALKKYQTHTNAGM 286 >4ZWV-A nrPDB Length = 372 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 46/277 (16%), Positives = 94/277 (33%), Gaps = 45/277 (16%) Query: 112 ATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNG 171 + + + Y P ES LA R SG + L L+ Sbjct: 15 TALDRVAEVFASGYL---GQGPRVAEFESALAARLGNPRVVSVHSGTSGLCLALRLLDAP 71 Query: 172 ---EEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVN------TTKLDEVAAAIGPQTKLVW 222 +E+++ + + + + G + V+ T LD++ I P T+ + Sbjct: 72 EERDEVLSTPLTFEAT----NWAILADGRRITWVDVDPATLTMDLDDLERKISPATRAII 127 Query: 223 LESPTNPRQQISDIRKISEMA-HAQGAL--VLVDNSIMSPVLSRPLELGAD--IVMHS-- 275 + T + + I + A G V+ D + R + LG+ + + S Sbjct: 128 VVHWTGYPVDLDRLAGILDRAEREHGFRPAVIEDCAHAWGASYRGVPLGSHGNMCVFSFQ 187 Query: 276 ATKFIAGHSDVMAGVLAVKGEKLAKEV-----YFLQNSEGSGLAPFD------------- 317 A K + D G+L + G++L + Y + + +D Sbjct: 188 ALKHLTC-GD--GGLLTLPGDELHERAMLRRFYGIDRTADRLRGAYDVAEWGLKWHMTDL 244 Query: 318 -CWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVK 353 + L ++T+ ++ +ENA L+ P ++ Sbjct: 245 NAAIGLANLETVDEQLRLHRENAAFYDKELTGVPGLE 281 >2X5D-A nrPDB Length = 412 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 20/119 (16%), Positives = 45/119 (37%), Gaps = 14/119 (11%) Query: 149 DRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKL- 207 + S + + +G+ I+ + Y + V+ G V+ V Sbjct: 101 EAIVTIGSKEGLAHLMLATLDHGDTILVPNPSY--PIHIYGAVIA--GAQVRSVPLVPGI 156 Query: 208 ---DEVAAAIG---PQTKLVWLESPTNPRQQISDI---RKISEMAHAQGALVLVDNSIM 257 +E+ AI P+ +++ L P+NP Q ++ ++ +A +V+ D + Sbjct: 157 DFFNELERAIRESIPKPRMMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYA 215 >3EUC-A nrPDB Length = 367 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 41/211 (19%), Positives = 78/211 (36%), Gaps = 24/211 (11%) Query: 90 LLVNLDNKFDPFD-----AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAK 144 + + D AM P + A G R P+ +AL + L + Sbjct: 19 RAMGAYHVPDSHGLVKLDAMENPYRLPPALRSELAARLGEVALNRYPVPSSEALRAKLKE 78 Query: 145 LDKADRA--FCFTSGMAALSAVTHLI--KNGEEIVAGDD---VYGGSDRLLSQVVPRSGV 197 + + +G + ++ L + G +++A +Y S + + GV Sbjct: 79 VMQVPAGMEVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQF--AGLEFVGV 136 Query: 198 VVKRVNTTKLDEVAAAIGP-QTKLVWLESPTNPRQQI---SDIRKISEMAHAQ--GALVL 251 ++ T + AA+ Q +V+L P NP + +D+ I A +LV+ Sbjct: 137 PLRADFTLDRGAMLAAMAEHQPAIVYLAYPNNPTGNLFDAADMEAIVRAAQGSVCRSLVV 196 Query: 252 VDNSIMS----PVLSRPLELGADIVMHSATK 278 VD + +SR + G +VM + +K Sbjct: 197 VDEAYQPFAQESWMSRLTDFGNLLVMRTVSK 227 >4P3M-A nrPDB Length = 429 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 38/193 (19%), Positives = 67/193 (34%), Gaps = 25/193 (12%) Query: 140 SLLAKLDKADRAFCFT-SGMAALSAVT-HLIKNGEEIVAGDDVYGGSDRLLSQV------ 191 L AD A SG A +AV L G+ I+ +GG S V Sbjct: 80 ERAKSLFGADYANVQPHSGSQANAAVYQALCAPGDTILGMSLAHGGHLTHGSHVSFSGKM 139 Query: 192 --VPRSGV--VVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQG 247 + G+ ++ +++ +A P + + + I D K E+A G Sbjct: 140 YNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSAYS----GIVDWAKFREIADKVG 195 Query: 248 ALVLVD-----NSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV 302 A + VD + + + P+ AD+V + K + G G++ K + ++ Sbjct: 196 AYLFVDMAHVAGLVAAGLYPNPVPF-ADVVTTTTHKTLGGPR---GGLILAKANEAIEKK 251 Query: 303 YFLQNSEGSGLAP 315 G P Sbjct: 252 LNSAVFPGQQGGP 264 >6BLG-A nrPDB Length = 379 Score = 42.3 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 73/226 (32%), Gaps = 40/226 (17%) Query: 100 PFDAMSTPL------YQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFC 153 PF+A P+ Y + +G + TR +E +A Sbjct: 6 PFNA--PPVVGTELDYMQSAMNSGKLCGDGGF--TRRCQ---QWMEQRF----GTAKALL 54 Query: 154 FTSGMAAL--SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT------T 205 S A+L +A+ I+ G+E++ Y + + G + V+ Sbjct: 55 TPSCTASLEMAALLLDIQPGDEVIM--PSY--TFVSTANAFVLRGAKIVFVDIRRDTMNI 110 Query: 206 KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNS--IMSPVLSR 263 + AAI +T+ + P + ++ I +A V+ D + +MS R Sbjct: 111 DETLIEAAITDKTRAI---VPVHYAGVACEMDTIMAIADKYNLFVVEDAAQGVMSTYKGR 167 Query: 264 PLELGADI---VMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQ 306 L I H + AG G + L + ++ Sbjct: 168 ALGTIGHIGCFSFHETKNYTAGGE---GGATLINDRTLVERAEIIR 210 >4IX8-A nrPDB Length = 444 Score = 42.3 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 35/221 (15%), Positives = 71/221 (32%), Gaps = 30/221 (13%) Query: 64 QTHSTVNNTTDSLNTMNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPS-AIEN 122 +T +NN TD++ ++ S L +++ + TP T + + Sbjct: 48 RTLQPLNNLTDNMKP----SRSTKSNLRLSIG-DPTVDGNLKTPDIVTEAMVDVVRSGKF 102 Query: 123 GPYDYTRSGNPTRDALE---SLLAKLDKADRAF-----CFTSG--MAALSAVTHLIKNGE 172 Y T + R + + A TSG A + A+T L G+ Sbjct: 103 NGYPPTVGADNLRQVVSTYWRRFCQTKSRQEALKWENVIITSGVSQAIVLALTALCNEGD 162 Query: 173 EIVAGDDVYGGSDRLLSQVVPRSGVVVKR--VNTT-----KLDEVAAAIGPQTKLVWLES 225 I+ + + G+ + ++ + L A + TK + + Sbjct: 163 NILVCAPSFPHYKSVCDS----YGIECRYYYLDPSKSWECDLRAAAGMVDSHTKAFVIIN 218 Query: 226 PTNP---RQQISDIRKISEMAHAQGALVLVDNSIMSPVLSR 263 P+NP + + I + ++ D VL+ Sbjct: 219 PSNPCGSNFSRAHVSDIIDFCQQHQIPLISDEIYAEMVLNN 259 >3MAF-B nrPDB Length = 518 Score = 41.9 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 45/140 (32%), Gaps = 19/140 (13%) Query: 183 GSDRLLSQVVPRSGVVVKRVNT-----TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIR 237 + + G+ + R + + AI P T +V +P P + I Sbjct: 204 SAHAAFDKAAQYFGIKLVRTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVVDPIP 263 Query: 238 KISEMAHAQGALVLVD---NSIMSPVLSR------PLEL---GADIVMHSATKFIAGHSD 285 +I+ +A G VD + P R P + G V K+ G+ Sbjct: 264 EIAALAAEHGIGCHVDACLGGFILPWAERLGYPVPPFDFRLEGVTSVSADTHKY--GYGA 321 Query: 286 VMAGVLAVKGEKLAKEVYFL 305 V+ + L YF+ Sbjct: 322 KGTSVILYRRPDLLHYQYFI 341 >3H7F-A nrPDB Length = 447 Score = 41.5 bits (96), Expect = 9e-04, Method: Composition-based stats. Identities = 56/246 (22%), Positives = 91/246 (36%), Gaps = 35/246 (14%) Query: 135 RDALESLLAKLDKADRAFCFT-----SGMAALSAVT-HLIKNGEEIVAGDDVYGG--SDR 186 D +E+L KA F SG A +AV L+ GE ++ D GG + Sbjct: 89 VDVVENLARDRAKALFGAEFANVQPHSGAQANAAVLHALMSPGERLLGLDLANGGHLTHG 148 Query: 187 L---LSQVVPRSGVVVKRVNTT----KLDEVAA-AIGPQTKLVWLESPTNPRQQISDIRK 238 + S + +G V+ +D V A A+ + K++ P ++ D Sbjct: 149 MRLNFSGKLYENG--FYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAYP--RVLDFAA 204 Query: 239 ISEMAHAQGALVLVD-----NSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAV 293 +A GA +LVD + + + P+ AD+V + K + G +G++ Sbjct: 205 FRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPH-ADVVSTTVHKTLGGGR---SGLIVG 260 Query: 294 KGE--KLAKEVYFLQNSEGS---GLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSS 348 K + K F G +A L + A R + AR IA L + Sbjct: 261 KQQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFADRQRRTLSGARIIADRLMA 320 Query: 349 HPRVKK 354 P V K Sbjct: 321 -PDVAK 325 >3DZZ-A nrPDB Length = 391 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 45/115 (39%), Gaps = 18/115 (15%) Query: 153 CFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT------ 204 F SG+ A + V G++I+ + VY + V+ +G V + Sbjct: 89 VFASGVVPAISAMVRQFTSPGDQILVQEPVY----NMFYSVIEGNGRRVISSDLIYENSK 144 Query: 205 --TKLDEVAAAI-GPQTKLVWLESPTNP---RQQISDIRKISEMAHAQGALVLVD 253 ++ + P +++ +P NP ++++I+E+ L++ D Sbjct: 145 YSVNWADLEEKLATPSVRMMVFCNPHNPIGYAWSEEEVKRIAELCAKHQVLLISD 199 >4WXB-A nrPDB Length = 428 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 56/264 (21%), Positives = 94/264 (35%), Gaps = 37/264 (14%) Query: 115 KQPSAIENGPYDYTRSGNPTRDALE----SLLAKLDKADRAFCFT-SGMAALSAV-THLI 168 + + G Y G D +E KL A A SG A +AV LI Sbjct: 65 NKYAEGYPGKRYYG--GTAVIDVVETLAIERAKKLFGAKFANVQPHSGSQANAAVYMSLI 122 Query: 169 KNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV--------NTTKLDEVAA-AIGPQTK 219 + G+ ++ D GG + V SG V D + A A + K Sbjct: 123 QPGDTVMGMDLSAGGHLTHGAPV-SFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPK 181 Query: 220 LVWLESPTNPRQQISDIRKISEMAHAQGALVLVD-----NSIMSPVLSRPLELGADIVMH 274 L+ + + +I D K E+A A GA ++VD + S P+ A + Sbjct: 182 LIV--AGASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPY-AHVTTT 238 Query: 275 SATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGI---KTMALR 331 + K + G G++ E +AK++ G P + + + + + + Sbjct: 239 TTHKTLRGPR---GGLILTDDEDIAKKLNSAV-FPGLQGGPLEHVIAAKAVALKEALDPA 294 Query: 332 IEKQQE----NARKIAMYLSSHPR 351 ++ E NA +A + HP Sbjct: 295 FKEYGENVIKNAAAMADVFNQHPD 318 >2HUU-A nrPDB Length = 393 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 48/118 (40%), Gaps = 11/118 (9%) Query: 148 ADRAFCFTSGMAAL-SAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTK 206 A SG + + + +L+++G+ I+ G G + + R G V+ V + Sbjct: 71 ATFCLS-ASGHGGMEATLCNLLEDGDVILIGHT--GHWGDRSADMATRYGADVRVVKSKV 127 Query: 207 LDEVA------AAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMS 258 ++ A + + +++L + + + + + H L++VD ++ S Sbjct: 128 GQSLSLDEIRDALLIHKPSVLFLTQGDSSTGVLQGLEGVGALCHQHNCLLIVD-TVAS 184 >3LWS-A nrPDB Length = 357 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 50/269 (18%), Positives = 85/269 (31%), Gaps = 43/269 (15%) Query: 110 QTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSG-MAALSAVTHLI 168 F A E Y + E A + D A F SG MA A+ Sbjct: 27 LKTAFA-AVADEMASDQYGTG--AIIEPFEQKFADVLGMDDAVFFPSGTMAQQVALRIWS 83 Query: 169 KNGEE-IVAGDDVYGGSDRLLSQ---VVPRSGVVVKRVNTTK----LDEVAAAIGPQTKL 220 + VA + + + + + V LDE+ A P Sbjct: 84 DETDNRTVAYHPL---CHLEIHEQDGLKELHPIETILVGAADRLMTLDEIKAL--PDIAC 138 Query: 221 VWLESPTNPRQQIS----DIRKISEMAHAQGALVLVDNS--I-MSPVLSRPLELGA---D 270 + LE P ++ ++ IS +G + +D + M P + A D Sbjct: 139 LLLELPQREIGGVAPAFSELETISRYCRERGIRLHLDGARLFEMLPYYEKTAAEIAGLFD 198 Query: 271 IVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGS---GLAPF----DCWLCLR 323 + S K + G +AG + + + G L P+ D + LR Sbjct: 199 SIYISFYKGLGG----IAGAILAGPAAFCQTARIWKRRYGGDLISLYPYIVSADYYYELR 254 Query: 324 GIKTMALRIEKQQENARKIAMYLSSHPRV 352 R+ + E A+++A ++ P V Sbjct: 255 -----KDRMGQYYEQAKQLAEQFNALPGV 278 Score = 28.8 bits (63), Expect = 6.0, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 19/46 (41%) Query: 272 VMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFD 317 T I+GH GVL +A E+ Q G+ + PF+ Sbjct: 8 SFQQTTGQISGHGKRNVGVLKTAFAAVADEMASDQYGTGAIIEPFE 53 >2FNU-A nrPDB Length = 375 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 59/187 (31%), Gaps = 29/187 (15%) Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHLIKN-------GEEIVAGDDVYGGSDRLLSQ 190 E L + A F S A SA+ L +N EI+ + + + Sbjct: 37 FEEALCEFLGVKHALVFNS---ATSALLTLYRNFSEFSADRNEIITTPISFVAT----AN 89 Query: 191 VVPRSGVVVKRVNT-----TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHA 245 ++ SG + I +TK + + + ++ + ++ Sbjct: 90 MLLESGYTPVFAGIKNDGNIDELALEKLINERTKAI---VSVDYAGKSVEVESVQKLCKK 146 Query: 246 QGALVLVDNSIMSPVLSRPLELG----ADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKE 301 L D+S + ++G A + A K I + G + +L ++ Sbjct: 147 HSLSFLSDSSHALGSEYQNKKVGGFALASVFSFHAIKPI---TTAEGGAVVTNDSELHEK 203 Query: 302 VYFLQNS 308 + ++ Sbjct: 204 MKLFRSH 210 >5DJ3-A nrPDB Length = 376 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 12/79 (15%), Positives = 37/79 (46%), Gaps = 5/79 (6%) Query: 183 GSDRLLSQVVPRSGVVVKRV--NTTKLDEVAAAIGPQTKLVWLESPTNPRQQIS---DIR 237 + ++ ++ +G+ + V + +++A + V++ +P NP ++ +R Sbjct: 113 PTFDNIADLLRGNGLDLVPVEEDALHGADLSAELLSSVGCVFVTTPNNPTGRVLAEERLR 172 Query: 238 KISEMAHAQGALVLVDNSI 256 +++E G ++ +D S Sbjct: 173 RLAEQCAEHGTVLALDTSF 191 >3JTX-A nrPDB Length = 396 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 36/213 (16%), Positives = 70/213 (32%), Gaps = 42/213 (19%) Query: 129 RSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNG--EEIVAGDDVYGGSDR 186 R T DA +L L + F F + V + + +G IV+ + Y + Sbjct: 82 RYDGLTVDADNEILPVLGSREALFSF------VQTVLNPVSDGIKPAIVSPNPFY----Q 131 Query: 187 LLSQVVPRSGVVVKRVNTT------KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRK-- 238 + G + N ++ + +TKLV++ SP NP + D+ Sbjct: 132 IYEGATLLGGGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWK 191 Query: 239 -ISEMAHAQGALVLVDNSIMS---------PVLSRPLELGAD----IVMHSATKFIAGHS 284 + ++ G ++ D L +LG ++ S +K Sbjct: 192 EVFDLQDKYGFIIASDECYSEIYFDGNKPLGCLQAAAQLGRSRQKLLMFTSLSKRSN--- 248 Query: 285 DVMAGV---LAVKGEKLAKEVYFLQNSEGSGLA 314 + G+ +L K + GS ++ Sbjct: 249 --VPGLRSGFVAGDAELLKNFLLYRTYHGSAMS 279 >1D2F-A nrPDB Length = 390 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 58/151 (38%), Gaps = 24/151 (15%) Query: 122 NGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTS-----GMAALSAVTHLIKN----GE 172 +G + Y+R N D + +A S G + + V+ LI+ GE Sbjct: 56 HGVFGYSRWKN---DEFLAAIAHWFSTQHYTAIDSQTVVYGPSVIYMVSELIRQWSETGE 112 Query: 173 EIVAGDDVYG-------GSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLES 225 +V Y G+ R + V + KL+ V A P+ K++ L S Sbjct: 113 GVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLA--KPECKIMLLCS 170 Query: 226 PTNPRQQI---SDIRKISEMAHAQGALVLVD 253 P NP ++ ++ ++++ G V+ D Sbjct: 171 PQNPTGKVWTCDELEIMADLCERHGVRVISD 201 >5WGB-A nrPDB Length = 426 Score = 39.2 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 69/358 (19%), Positives = 119/358 (33%), Gaps = 77/358 (21%) Query: 125 YDYTRSGNPTRDALESLLAKLDKAD-RAFCFTSGMA-----ALSAVTHLIKN-GEEIVAG 177 + Y + +A L AD R FTSG A+ V ++ + ++ Sbjct: 62 HAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITT 121 Query: 178 DDVYGGSDRLLSQVVPRSGVVVKRV-----NTTKLDEVAAAIGPQTKLVWLESPTNPRQQ 232 + + + G V + L E+ AAI P T LV + + N Sbjct: 122 QTEHKCVLDSC-RSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGV 180 Query: 233 ISDIRKISEMAHAQGALVLVDNSIMSPVLSRPL---ELGADIVMHSATKFIAGHSDVMAG 289 I +I + ++ D + + PL ++ D++ S K + Sbjct: 181 KQPIAEIGRICSSRKVYFHTDAAQAVGKI--PLDVNDMKIDLMSISGHKIYGPKG--VGA 236 Query: 290 VLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKT------MALRIEKQQENARKIA 343 + + ++ V LQ+ G RG+++ + + + E A++ Sbjct: 237 IYIRRRPRV--RVEALQSGGGQ----------ERGMRSGTVPTPLVVGLGAACEVAQQEM 284 Query: 344 MYLSSHPRVKKV-------YYAGLPD-----HPGHHLHFSQAKGAGSV-FSFITGSVALS 390 Y H R+ K+ LPD P HH G + SF Sbjct: 285 EY--DHKRISKLSERLIQNIMKSLPDVVMNGDPKHH-------YPGCINLSFA---YVEG 332 Query: 391 KHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDL----VRISAG 444 + L+ K +A+S GS S + P+ V A G EDL +R G Sbjct: 333 ESLLMALK--DVALSSGS--------ACTSASLEPSYVLRAIGTDEDLAHSSIRFGIG 380 >4CVQ-A nrPDB Length = 431 Score = 39.2 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 44/103 (42%), Gaps = 14/103 (13%) Query: 161 LSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRS-GVVVKRVNTT------KLDEVAAA 213 + A+ L+ +G+E++ Y L + V S G V + LD++ A Sbjct: 135 VQAMQALLNSGDEMLVPAPDY----PLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAK 190 Query: 214 IGPQTKLVWLESPTNPRQQISDIR---KISEMAHAQGALVLVD 253 I P+T+ + + +P NP + +I E+A ++ D Sbjct: 191 ITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFAD 233 >6C9E-A nrPDB Length = 422 Score = 39.2 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 29/57 (50%) Query: 205 TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVL 261 L+E + TK+V + +N I+ ++ + +MAH GA VL+D + + L Sbjct: 168 VILEEFERKLNENTKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHL 224 >3FFH-A nrPDB Length = 363 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 9/90 (10%) Query: 183 GSDRLLSQVVPRSGVVVKRVNTT-----KLDEVAAAIGPQTKLVWLESPTNPR---QQIS 234 + Q G V+ + L+ + AI +T +VW+ +P NP +++ Sbjct: 116 PTFVQYRQNALIEGAEVREIPLLQDGEHDLEGMLNAIDEKTTIVWICNPNNPTGNYIELA 175 Query: 235 DIRKISEMAHAQGALVLVDNSIMSPVLSRP 264 DI+ + + LV++D + + V +P Sbjct: 176 DIQAFLDRVPS-DVLVVLDEAYIEYVTPQP 204 >1LC8-A nrPDB Length = 364 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 37/241 (15%), Positives = 78/241 (32%), Gaps = 61/241 (25%) Query: 185 DRLLSQVVPRSGVVVKRVNTTKLDEVA------AAIGPQTKLVWLESPTNPRQQISD--- 235 + + +SG ++R + + D A+ P ++L +P NP + + Sbjct: 108 FAEYGRALAQSGCEIRRWSLREADGWQLTDAILEALTPDLDCLFLCTPNNPTGLLPERPL 167 Query: 236 IRKISEMAHAQGALVLVDNSIMS---------PVLS-RPLELGADIVMHSATKFIAGHSD 285 ++ I++ + +++D + + P L P V+ S TKF A Sbjct: 168 LQAIADRCKSLNINLILDEAFIDFIPHETGFIPALKDNPHIW----VLRSLTKFYAIPGL 223 Query: 286 VMAGVLAVKGEKLAK--------EVYFLQNSEGSGLAPFDCW------------------ 319 + ++ +A+ V L G W Sbjct: 224 RLGYLVNSDDAAMARMRRQQMPWSVNALAALAGEVALQDSAWQQATWHWLREEGARFYQA 283 Query: 320 LCLRGIKT--------MALRIEKQQENARKIAMYLSSHPRVK-KVYYAGLPDHPGHHLHF 370 LC + T + LR E++ + ++ L+ ++ Y GL D + + Sbjct: 284 LCQLPLLTVYPGRANYLLLRCEREDIDLQR--RLLTQRILIRSCANYPGL-DSRYYRVAI 340 Query: 371 S 371 Sbjct: 341 R 341 >4FL0-A nrPDB Length = 456 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 61/321 (19%), Positives = 112/321 (34%), Gaps = 48/321 (14%) Query: 23 LISKNSPTSVSISKVPT----WEKKQISNRNSFKLNCVMEKSVDGQTHSTVNNTTDSLNT 78 S SP S SK+P +E K++ N +EK + N +N Sbjct: 6 FFSSASPLCSSPSKIPKASLDFEMKKLGGSTKLVRNVNLEKLKN-------NYLFPEINR 58 Query: 79 MNIKE-EASVSTLLVNLDNKFDPFDAMSTPLYQTAT-----FKQPSAIENGPYDYT-RSG 131 ++ E + L++L + P+ + T F + G Y G Sbjct: 59 RELEHIEKHPNVQLISLG-----TGDTTEPIPEQITSHMSNFAHGLSTVEGYRGYGLEQG 113 Query: 132 NPT-RDAL-ESLLAKLDKADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDDVY------- 181 N T R A+ E+ L + G + +S + L+ + I D + Sbjct: 114 NKTLRKAIAETFYRDLHVKSNEVFVSDGAQSDISRLQLLLGSNVTIAVQDPTFPAYIDSS 173 Query: 182 ---GGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISD--- 235 G + + VV A+ P+T +++ SP NP ++ Sbjct: 174 VIIGQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQ 233 Query: 236 IRKISEMAHAQGALVLVDNSIM------SP--VLSRPLELGADIVMHSATKFIAGHSDVM 287 + ++ + A G++++ D++ SP + P I + S +KF AG + V Sbjct: 234 LHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKF-AGFTGVR 292 Query: 288 AGVLAVKGEKLAKEVYFLQNS 308 G + E L + + N Sbjct: 293 LGWSIIPDELLYSNGFPIIND 313 >3A2B-A nrPDB Length = 398 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 83/204 (40%), Gaps = 31/204 (15%) Query: 128 TRSGNPTRDA---LESLLAKLDKADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDD---- 179 +R N T D LE L+ + A F++G + L ++ L+ + I+ + Sbjct: 80 SRFLNGTLDIHVELEEKLSAYVGKEAAILFSTGFQSNLGPLSCLMGRNDYILLDERDHAS 139 Query: 180 VYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQT-KLVWLESPTNPRQQISDIRK 238 + GS S+V + N L + + + KL+ + + I ++ + Sbjct: 140 IIDGSRLSFSKV-----IKYGHNNMEDLRAKLSRLPEDSAKLICTDGIFSMEGDIVNLPE 194 Query: 239 ISEMAHAQGALVLVDNSIMSPVLSR---------PLELGADIVMHSATKFIAGHSDVMAG 289 ++ +A+ A V+VD++ V+ L D++M + +K +A + G Sbjct: 195 LTSIANEFDAAVMVDDAHSLGVIGHKGAGTASHFGLNDDVDLIMGTFSKSLA----SLGG 250 Query: 290 VLAVKGEKLAKEVYFLQNSEGSGL 313 +A + + FL+++ S + Sbjct: 251 FVAGDADVID----FLKHNARSVM 270 >3N0L-A nrPDB Length = 417 Score = 38.4 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 38/162 (23%), Positives = 68/162 (41%), Gaps = 21/162 (12%) Query: 155 TSGMAALSAVTH-LIKNGEEIVAGDDVYGGSDRLLSQVVPR--------SGVVVK-RVNT 204 SG A V LI G++I+ D +GG ++V GV + R++ Sbjct: 94 NSGSQANQGVYAALINPGDKILGMDLSHGGHLTHGAKVSSSGKMYESCFYGVELDGRIDY 153 Query: 205 TKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVL--- 261 K+ E+A + KL+ + ++ D K E+A GA + D + ++ ++ Sbjct: 154 EKVREIAK--KEKPKLIVCG--ASAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAG 209 Query: 262 SRPLELGADIVMHSAT-KFIAGHSDVMAGVLAVKGEKLAKEV 302 P V+ S T K + G G++ E+LAK++ Sbjct: 210 EHPSPFPYAHVVSSTTHKTLRGPR---GGIIMTNDEELAKKI 248 >6MRE-A nrPDB Length = 420 Score = 38.0 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 58/141 (41%), Gaps = 13/141 (9%) Query: 168 IKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV-----NTTKLDEVAAAIGPQTKLVW 222 ++ G+ I+ + + + R G ++ + T +L+ + +T+L+ Sbjct: 124 VRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLA 183 Query: 223 LESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGA---DIVMHSATKF 279 + +N + + ++ +AH GA VLVD V+ P+++ A D + S K Sbjct: 184 ITHVSNVLGTENPLAEMITLAHQHGAKVLVDG--AQAVMHHPVDVQALDCDFYVFSGHKL 241 Query: 280 IAGHSDVMAGVLAVKGEKLAK 300 G+L VK L + Sbjct: 242 YGPTG---IGILYVKEALLQE 259 >1YJS-A nrPDB Length = 419 Score = 38.0 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 59/162 (36%), Gaps = 29/162 (17%) Query: 110 QTATFKQPSAIEN--GPYDYTRSGNPTRDALES----LLAKLDKADRAFCFT-SGMAALS 162 T + + G +Y D +E +L A+ A SG A Sbjct: 47 LTNKYAEGYPGRRYYGGCEY-------VDIVEELARERAKQLFGAEHANVQPHSGAQANM 99 Query: 163 AV-THLIKNGEEIVAGDDVYGG--------SDRLLSQVVPRSGV--VVKRVNTTKLDEVA 211 AV ++++G+ ++ + +GG + + GV ++ + E A Sbjct: 100 AVYFTVLEHGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVAYGVDPETHVIDYDDVREKA 159 Query: 212 AAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD 253 P KL+ + P +I D K E+A GA ++VD Sbjct: 160 RLHRP--KLIVAAASAYP--RIIDFAKFREIADEVGAYLMVD 197 >3ISL-A nrPDB Length = 416 Score = 37.6 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 56/142 (39%), Gaps = 16/142 (11%) Query: 123 GPYDYTRSG--NPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV 180 G +D +G N T + L L ++ TS + + +I+ ++++ + Sbjct: 36 GQFDPAFTGIMNETMEMLRELFQTKNRWAYPIDGTSRAGIEAVLASVIEPEDDVLI--PI 93 Query: 181 YGGSDRLLSQVVPRSGVVV--------KRVNTTKLDEVAAAIGPQ-TKLVWLESPTNPRQ 231 YG LL+++ R G V + + + P+ +V E+ T Sbjct: 94 YGRFGYLLTEIAERYGANVHMLECEWGTVFDPEDIIREIKKVKPKIVAMVHGETSTG--- 150 Query: 232 QISDIRKISEMAHAQGALVLVD 253 +I ++ I E + AL +VD Sbjct: 151 RIHPLKAIGEACRTEDALFIVD 172 >3G8M-A nrPDB Length = 417 Score = 37.6 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 36/180 (20%), Positives = 64/180 (35%), Gaps = 33/180 (18%) Query: 110 QTATFKQPSAIEN--GPYDYTRSGNPTRDALES----LLAKLDKADRAFCFT-SGMAALS 162 T F + + G +Y D +E +L AD A SG A Sbjct: 51 LTNKFAEGYPGKRYYGGCEY-------VDIVEQLAIDRAKELFGADYANVQPHSGSQANF 103 Query: 163 AV-THLIKNGEEIVAGDDVYGGSDRLLSQV--------VPRSGVVVK-RVNTTKLDEVAA 212 AV T L++ G+ ++ + +GG S V + G+ ++ L+ Sbjct: 104 AVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLE--KQ 161 Query: 213 AIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD-----NSIMSPVLSRPLEL 267 A + K++ + D K+ E+A + GA + VD + + V P+ Sbjct: 162 AKEHKPKMIIGGFSA--YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPH 219 >1IJI-A nrPDB Length = 356 Score = 37.6 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 164 VTHLIKNG-EEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTK-LDEVAAAIGPQ---T 218 + + G + I+ YG + S GV + V T I + Sbjct: 92 IRAFCEPGKDAILYCPPTYG----MYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGV 147 Query: 219 KLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVD 253 K+V++ SP NP Q+ D R + E+ + A+V+ D Sbjct: 148 KVVYVCSPNNPTGQLINPQDFRTLLELTRGK-AIVVAD 184 >1DJ9-A nrPDB Length = 384 Score = 37.6 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 54/130 (41%), Gaps = 6/130 (4%) Query: 135 RDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPR 194 ALE LA+ RA F SG AA AV + E+ +A D + S L + Sbjct: 86 HQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIAADRL---SHASLLEAASL 142 Query: 195 SGVVVKRVNTTKLDEVAAAIG---PQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL 251 S ++R + +A + P ++V E + + + +I ++ ++ Sbjct: 143 SPSQLRRFAHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLM 202 Query: 252 VDNSIMSPVL 261 VD++ + V+ Sbjct: 203 VDDAHGTGVI 212 >5JAY-A nrPDB Length = 402 Score = 37.6 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 54/122 (44%), Gaps = 8/122 (6%) Query: 138 LESLLAKLDKA----DRAFCFTSG-MAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192 LE LA+ RA F++G MA L+ +T L G + + D + + + Sbjct: 97 LEDDLAEFVGGFVENARALYFSTGYMANLATLTALAGRGTTLFS--DALNHASLIDGARL 154 Query: 193 PRSGVVV-KRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL 251 R+ V + +T L + A K++ ++ + I+ + ++ E+A GA ++ Sbjct: 155 SRADVQIYPHCDTDALSAMLEASDADVKVIVSDTVFSMDGDIAPLPRLLELAEQHGAWLI 214 Query: 252 VD 253 VD Sbjct: 215 VD 216 >5VNX-A nrPDB Length = 393 Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 34/122 (27%), Positives = 56/122 (45%), Gaps = 8/122 (6%) Query: 138 LESLLAKLDK----ADRAFCFTSG-MAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192 LE LA A RA F++G MA L+AVT L G++ D + + + Sbjct: 89 LEDELAGFAGGFSDAPRALYFSTGYMANLAAVTAL--AGKDATIFSDALNHASLIDGTRL 146 Query: 193 PRSGVVV-KRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL 251 R+ V V +T L + A QTKL+ ++ + I+ + ++ +A GA ++ Sbjct: 147 SRATVQVYPHADTATLGALLEACTSQTKLIVTDTVFSMDGDIAPLAELLALAERHGAWLV 206 Query: 252 VD 253 VD Sbjct: 207 VD 208 >3IF2-A nrPDB Length = 444 Score = 37.3 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 28/63 (44%), Gaps = 3/63 (4%) Query: 201 RVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQIS---DIRKISEMAHAQGALVLVDNSIM 257 RV+ L+ + A + + PTNP + ++ ++E+A +++DN+ Sbjct: 190 RVDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYG 249 Query: 258 SPV 260 P Sbjct: 250 MPF 252 >6F77-B nrPDB Length = 400 Score = 37.3 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 11/76 (14%) Query: 161 LSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNT-------TKLDEVAAA 213 +A + G+E+V + ++V G V T K +++ A Sbjct: 105 FNAFMATLNPGDEVVIPAPYW----VSYPEMVALCGGTPVFVPTRQENNFKLKAEDLDRA 160 Query: 214 IGPQTKLVWLESPTNP 229 I P+TK SP+NP Sbjct: 161 ITPKTKWFVFNSPSNP 176 >2ZC0-A nrPDB Length = 407 Score = 37.3 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Query: 157 GMAALSAVTH-LIKNGEEIVAGDDVYGGSDRLLSQVVPRS-GVVVK----RVNT--TKLD 208 G AL + LI G+ ++ + Y + Q+ + GV V RV+ K+ Sbjct: 107 GTGALDLLGRVLIDPGDVVITENPSYINTLLAFEQLGAKIEGVPVDNDGMRVDLLEEKIK 166 Query: 209 EVAAAIGPQTKLVW-LESPTNP---RQQISDIRKISEMAHAQGALVLVDNSI 256 E+ A G + KL++ + + NP + + + E+A L++ D + Sbjct: 167 ELK-AKGQKVKLIYTIPTGQNPMGVTMSMERRKALLEIASKYDLLIIEDTAY 217 >2EZ1-A nrPDB Length = 456 Score = 36.9 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 45/301 (14%), Positives = 96/301 (31%), Gaps = 65/301 (21%) Query: 138 LESLLAKLDKADRAFCFTSGMAALSAVTHL-IKNGEEIVAGDDVYGGSDRL--------L 188 LE + +L G A + ++ L IK G+ + ++Y + R Sbjct: 80 LERTVQELFGFKHIVPTHQGRGAENLLSQLAIKPGQYV--AGNMYFTTTRYHQEKNGAVF 137 Query: 189 SQVVPR----SGVVVKRVNTTKLDEVAAAIGPQTK--------LVWLESPTNPRQQISDI 236 +V +G+ + L ++ I + V + ++++ Sbjct: 138 VDIVRDEAHDAGLNIAFKGDIDLKKLQKLIDEKGAENIAYICLAVTVNLAGGQPVSMANM 197 Query: 237 RKISEMAHAQGALVLVDNSIM--SPVLSRPLELGAD-----IVMHSATKF-----IAGHS 284 R + E+ A G V D + + + E G + ++H + ++G Sbjct: 198 RAVRELTEAHGIKVFYDATRCVENAYFIKEQEQGFENKSIAEIVHEMFSYADGCTMSGKK 257 Query: 285 DV---MAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCW--LCLRGIKTMALRIEKQQENA 339 D + G L + +++ L + + L R ++ MA+ + + + Sbjct: 258 DCLVNIGGFLCMNDDEMFSSAKELVVVYEGMPS----YGGLAGRDMEAMAIGLREAMQ-- 311 Query: 340 RKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGS---VALSKHLVET 396 Y+ VK+V Y G + K AG G ++ E Sbjct: 312 ---YEYIEHR--VKQVRYLG-----------DKLKAAGVPIVEPVGGHAVFLDARRFCEH 355 Query: 397 T 397 Sbjct: 356 L 356 >3H14-A nrPDB Length = 391 Score = 36.9 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 66/200 (33%), Gaps = 25/200 (12%) Query: 71 NTTDSLNTMNIKEEASVSTLL----VNLDNKFDPFDAMSTPLYQTATFKQPSAIENGPYD 126 + D M++ E A + ++++ A P + + Y Sbjct: 9 SAVDPFIVMDVMEAARRAEEAGRRIIHMEVGQPGTGA---PRGAVEALAKSLETDALGYT 65 Query: 127 YTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALS---------AVTHLIKNGEEIVAG 177 G P AL +A+L G ++ A T L +G+ + G Sbjct: 66 VA-LGLP---ALRQRIARLYGEWYGVDLDPGRVVITPGSSGGFLLAFTALFDSGDRVGIG 121 Query: 178 DDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGP-QTKLVWLESPTNPRQQISD- 235 Y S R + + + V + +L V A + + SP NP + D Sbjct: 122 APGY-PSYRQILRALGLVPVDLPTAPENRLQPVPADFAGLDLAGLMVASPANPTGTMLDH 180 Query: 236 --IRKISEMAHAQGALVLVD 253 + + E A AQGA + D Sbjct: 181 AAMGALIEAAQAQGASFISD 200 >6ONN-A nrPDB Length = 402 Score = 36.9 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 53/122 (43%), Gaps = 8/122 (6%) Query: 138 LESLLAKLDKA----DRAFCFTSG-MAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVV 192 LE LA+ RA F++G MA L+ +T L G + + D + + + Sbjct: 97 LEDDLAEFAGGFVDNPRALYFSTGYMANLATLTALAGRGTTLFS--DSLNHASLIDGARL 154 Query: 193 PRSGVVV-KRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL 251 R+ + + + L + A KL+ ++ + I+ + ++ E+A GA ++ Sbjct: 155 SRADIQIYPHADAEALGAMLEASDAAVKLIVSDTVFSMDGDIAPLARLLELAEHHGAWLV 214 Query: 252 VD 253 VD Sbjct: 215 VD 216 >4Q6R-A nrPDB Length = 511 Score = 36.5 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 47/144 (32%), Gaps = 39/144 (27%) Query: 173 EIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT-----KLDEVAAAIGPQTKLVWLESPT 227 EIVA ++ G+ + RV T + + AI T ++ +P Sbjct: 177 EIVAPQSA----HAAFNKAASYFGMKIVRVPLTKMMEVDVRAMRRAISRNTAMLVCSTPQ 232 Query: 228 NPRQQISDIRKISEMAHAQGALVLVDN-------SIM--SPV-LSRPLEL---------- 267 P I + +++++A + VD M + L P + Sbjct: 233 FPHGVIDPVPEVAKLAVKYKIPLHVDACLGGFLIVFMEKAGYPLEHPFDFRVKGVTSISA 292 Query: 268 ----------GADIVMHSATKFIA 281 G+ +V++S K+ Sbjct: 293 DTHKYGYAPKGSSLVLYSDKKYRN 316 >5WT2-A nrPDB Length = 401 Score = 36.5 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 36/178 (20%), Positives = 60/178 (33%), Gaps = 18/178 (10%) Query: 168 IKNG-EEIVAG---DDVYGGSDRLLSQVVPRSGVVVKRVNTTK-----LDEVAAAIGPQT 218 +K G IV + L GV V + + ++V AI +T Sbjct: 90 LKKGKNHIVTTVAEHPAVRSTCNFLES----LGVEVTYLPINEHGSITAEQVREAITEKT 145 Query: 219 KLVWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVL-SRPLELGADIVMHSAT 277 LV + N I I +I + +G L D + L+ AD + SA Sbjct: 146 ALVSVMWANNETGLIFPIEEIGAICKEKGVLFHTDAVQAIGKIPVDVLKANADFLSFSAH 205 Query: 278 KFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDC-WLCLRGIKTMALRIEK 334 KF + G+ G L + ++ G + ++ G + M L +E Sbjct: 206 KFHGPKG--IGGLYIRSGVGLTPLFHGGEHMNGRRSGTLNVPYIVGMG-EAMKLAVEH 260 >2Z9W-A nrPDB Length = 392 Score = 36.5 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 31/175 (17%), Positives = 58/175 (33%), Gaps = 19/175 (10%) Query: 158 MAALSAVTHLIKNGEEIV-AGDDVYGGSDRLLSQVVP--RSGVVVKRVNTTKLDEVAAAI 214 + +A LI + ++ VYG ++ + V VA + Sbjct: 70 LGLEAAAASLISPDDVVLNLASGVYGKGFGYWAKRYSPHLLEIEVPYNEAIDPQAVADML 129 Query: 215 GPQTKLVWL-----ESPT---NPRQQISDIRKISEMAHAQGALVLVDNSIM-SPVLSRPL 265 ++ + ++P+ NP I I + A GA ++VD + + P Sbjct: 130 KAHPEITVVSVCHHDTPSGTINP------IDAIGALVSAHGAYLIVDAVSSFGGMKTHPE 183 Query: 266 ELGADIVMHSATKFIAG-HSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCW 319 + ADI + K + M GV K+ + S S + + W Sbjct: 184 DCKADIYVTGPNKCLGAPPGLTMMGVSERAWAKMKANPLAPRASMLSIVDWENAW 238 >4R2N-A nrPDB Length = 367 Score = 36.5 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 34/167 (20%), Positives = 63/167 (37%), Gaps = 32/167 (19%) Query: 148 ADRAFCFTSGMAALSAVTHLIKN--GEEIVAGDDVYGGSDRLLSQVVPRSG---VVVKRV 202 A G +L + G+E+V G S L V +G + V Sbjct: 76 APEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWR----SFELYPPQVRVAGAIPIQVPLT 131 Query: 203 NTT-KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHA--QGALVLVDNSIMSP 259 + T L + A + +T+L+++ +P NP + ++ A L+ +D + + Sbjct: 132 DHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVE- 190 Query: 260 VL---SRPLELG---AD---IVMHSATK----------FIAGHSDVM 287 + RP LG A +V+ + +K + GH DV+ Sbjct: 191 YIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVI 237 >4LW2-A nrPDB Length = 404 Score = 36.1 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 58/147 (39%), Gaps = 15/147 (10%) Query: 168 IKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV-----NTTKLDEVAAAIGPQTKLVW 222 ++ G+EI+ + + V ++G V ++ +D + I P+++++ Sbjct: 109 LQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPRSRILA 168 Query: 223 LESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKF-IA 281 L +N D+ + AH+ G +V+VD + + AD+ + + Sbjct: 169 LGQMSNVTGGCPDLARAITFAHSAGMVVMVDGA------QGAVHFPADVQQLDIDFYAFS 222 Query: 282 GH---SDVMAGVLAVKGEKLAKEVYFL 305 GH GVL K E L +L Sbjct: 223 GHKLYGPTGIGVLYGKSELLEAMSPWL 249 >3FDB-A nrPDB Length = 377 Score = 36.1 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 46/139 (33%), Gaps = 7/139 (5%) Query: 121 ENGPYDY--TRSGNPTRDALESLLAKLDKADRAFCFTSGM-AALSAVTHLIKNGEEIVAG 177 E Y + T + + + F + A+ H +++ Sbjct: 52 EAFGYQPDGSLLSQATAEFYADRYGYQARPEWIFPIPDVVRGLYIAIDHFTPAQSKVIVP 111 Query: 178 DDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISD-- 235 Y LLS R G+ + L +V + + L +P NP + Sbjct: 112 TPAYPPFFHLLSAT-QREGIFIDATGGINLHDVEKGFQAGARSILLCNPYNPLGMVFAPE 170 Query: 236 -IRKISEMAHAQGALVLVD 253 + ++ ++AH A VLVD Sbjct: 171 WLNELCDLAHRYDARVLVD 189 >3CQ5-A nrPDB Length = 369 Score = 36.1 bits (82), Expect = 0.032, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 44/143 (30%), Gaps = 23/143 (16%) Query: 133 PTRDALESL--LAKLDKADRAFCFT---------SGMAALSAVTHLIKNGEEIVAGDDVY 181 P RDA+E LA T S + G + Y Sbjct: 67 PERDAVELRDELAAYITKQTGVAVTRDNLWAANGSNEILQQLLQAFGGPGRTALGFQPSY 126 Query: 182 G-------GSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQIS 234 G+ + G + ++ E A P +V++ +P NP ++ Sbjct: 127 SMHPILAKGTHTEF--IAVSRGADFR-IDMDVALEEIRAKQPD--IVFVTTPNNPTGDVT 181 Query: 235 DIRKISEMAHAQGALVLVDNSIM 257 + + + + +V+VD + Sbjct: 182 SLDDVERIINVAPGIVIVDEAYA 204 >5VMB-A nrPDB Length = 425 Score = 35.7 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 44/237 (18%), Positives = 94/237 (39%), Gaps = 34/237 (14%) Query: 135 RDALES----LLAKLDKADRAFCFT-SGMAALSAV-THLIKNGEEIVAGDDVYGG----- 183 D +E +L AD A +G A SAV L+ G+ ++ +GG Sbjct: 78 VDVIEQMAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVLGMSLAHGGHLTHG 137 Query: 184 -----SDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRK 238 S + + V ++ +++ +A P+ + + + ++ D ++ Sbjct: 138 AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSAYS----RVVDWQR 193 Query: 239 ISEMAHAQGALVLVD-----NSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAV 293 ++A GA + VD + + V P+++ AD+ + K + G + +LA Sbjct: 194 FRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQI-ADVTTTTTHKTLRGPRSGL--ILAK 250 Query: 294 KGEKLAKEVY---FLQNSEGSGLAPFDC-WLCLRGIKTMALRIEKQQ--ENARKIAM 344 E++ K++ F N G + +C + + + +QQ +NA+ +A Sbjct: 251 ANEEIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDFKAYQQQVVKNAQAMAE 307 >3MC6-C nrPDB Length = 497 Score = 35.3 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 31/87 (35%), Gaps = 10/87 (11%) Query: 173 EIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT------KLDEVAAAIGPQTKLVWLESP 226 EI+A + G + G+ ++ V L +V I T L+ +P Sbjct: 160 EIIAPVTAHAG----FDKAAYYFGMKLRHVELDPTTYQVDLGKVKKFINKNTVLLVGSAP 215 Query: 227 TNPRQQISDIRKISEMAHAQGALVLVD 253 P DI + ++A + VD Sbjct: 216 NFPHGIADDIEGLGKIAQKYKLPLHVD 242 >3T32-A nrPDB Length = 383 Score = 33.8 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 45/111 (40%), Gaps = 9/111 (8%) Query: 152 FCFTSGM--AALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVV--VKRVNT--T 205 F++G+ A +++ K E ++ +Y +++ + V K+ +T Sbjct: 85 IVFSAGIVPALSTSIQAFTKENESVLVQPPIYPPFFEMVTTNNRQLCVSPLQKQNDTYAI 144 Query: 206 KLDEVAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEMAHAQGALVLVD 253 + + KL+ L SP NP ++ ++ K+ + +V+ D Sbjct: 145 DFEHLEKQFQQGVKLMLLCSPHNPIGRVWKKEELTKLGSLCTKYNVIVVAD 195 >3TQX-A nrPDB Length = 399 Score = 33.4 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 49/123 (39%), Gaps = 19/123 (15%) Query: 233 ISDIRKISEMAHAQGALVLVDNSIMSPVLSR-----PLELG----ADIVMHSATKFIAGH 283 I+D++ I ++A ALV+VD+S + P G DI+ + K + G Sbjct: 191 IADLKSICDLADKYNALVMVDDSHAVGFIGENGRGTPEYCGVADRVDILTGTLGKALGGA 250 Query: 284 SDVMAGVLAVKGEKL-----AKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQ-QE 337 S G + E + Y N+ + L +KT ++ KQ QE Sbjct: 251 S---GGYTSGHKEIIEWLRNRSRPYLFSNTVAPVIVA-TSLKVLELLKTEGPQLRKQLQE 306 Query: 338 NAR 340 N+R Sbjct: 307 NSR 309 >3QGU-A nrPDB Length = 449 Score = 33.4 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 32/171 (18%), Positives = 61/171 (35%), Gaps = 25/171 (14%) Query: 196 GVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEM---AHAQGALVLV 252 G+ N + +T +++ SP NP + +++E+ A G++++ Sbjct: 188 GIEYMVCNPDNHFFPDLSKAKRTDIIFFCSPNNPTGAAATRAQLTELVNFARKNGSILVY 247 Query: 253 DNSIMSPVLSRP------LEL-GAD---IVMHSATKFIAGHSDVMAGVLAVKGEKLAKEV 302 D + +S P E+ GAD I S +K+ + + K K A Sbjct: 248 DAAYAL-YISNPDCPKTIYEIPGADEVAIETCSFSKYAGFTGVRLGWTVVPKALKYANGE 306 Query: 303 YFLQNSEGSGLAPFD-----------CWLCLRGIKTMALRIEKQQENARKI 342 + F+ L G+K M I+ +ENA+ + Sbjct: 307 PVHADWNRVMTTCFNGASNIVQAGGLACLQPEGLKEMNAMIKFYKENAQIL 357 >3HDO-A nrPDB Length = 360 Score = 33.0 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 22/107 (20%), Positives = 37/107 (34%), Gaps = 9/107 (8%) Query: 164 VTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQT---KL 220 + GEEI Y + G V+ T + A P+ K+ Sbjct: 99 IRAFAAEGEEIGYVHPSY----SYYGTLAEVQGARVRTFGLT--GDFRIAGFPERYEGKV 152 Query: 221 VWLESPTNPRQQISDIRKISEMAHAQGALVLVDNSIMSPVLSRPLEL 267 +L +P P + I E+A ++++D + S LEL Sbjct: 153 FFLTTPNAPLGPSFPLEYIDELARRCAGMLVLDETYAEFAESNALEL 199 >4WBT-A nrPDB Length = 376 Score = 32.6 bits (73), Expect = 0.32, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 51/138 (36%), Gaps = 12/138 (8%) Query: 129 RSGNPTRDALESLLA-KLDKADRAFCFTSGMAAL--SAVTHLIKNGEEIVAGDDVYGGSD 185 + +P L+ LA L + G+ L V +++ G +V Y + Sbjct: 67 KYADPENHDLKQALARHLGTSPANIAIGEGIDGLLGQIVRLVVEAGAPVVTSLGGY-PTF 125 Query: 186 RLLSQVVPRSG--VVVKRVNT-TKLDEVAAAI-GPQTKLVWLESPTNPRQQISDIRKISE 241 V G V V + L+ + AA+ LV+L +P NP ++ Sbjct: 126 NY--HVAGHGGRLVTVPYADDREDLEGLLAAVGRENAPLVYLANPDNPMGSWWPAERVVA 183 Query: 242 MAHA--QGALVLVDNSIM 257 A A + L+++D + Sbjct: 184 FAQALPETTLLVLDEAYC 201 >3KE3-A nrPDB Length = 379 Score = 32.6 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 45/105 (42%), Gaps = 6/105 (5%) Query: 200 KRVNTTKLDEVAAAIGP-QTKLVW---LESPTNPRQQISDIRKISEMAHAQGALVLVDNS 255 K ++ A I ++ +V+ +E+ + I+ +SE H+ G L+++D Sbjct: 117 KPFAPVDIETAVAKIKEDKSAIVYAPHVETSSGIILSEEYIKALSEAVHSVGGLLVIDCI 176 Query: 256 IMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAK 300 V ELG D+++ + K S AG++ + + K Sbjct: 177 ASGCVWLDMKELGIDVLISAPQK--GWSSTPCAGLVMLSAAAIKK 219 >1C7O-A nrPDB Length = 399 Score = 32.6 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 43/107 (40%), Gaps = 16/107 (14%) Query: 159 AALSAVTHLIKNGEEIVAGDDVYGGSDRLLS---------QVVPRSGVVVKRVNTTKLDE 209 A +AV K G+ ++ VY + +++ + G ++ KL++ Sbjct: 101 AVFNAVREFTKPGDGVIIITPVYYPFFMAIKNQERKIIECELLEKDGYYT--IDFQKLEK 158 Query: 210 VAAAIGPQTKLVWLESPTNPRQQI---SDIRKISEMAHAQGALVLVD 253 ++ K + SP NP ++ +++KI ++ ++ D Sbjct: 159 LSK--DKNNKALLFCSPHNPVGRVWKKDELQKIKDIVLKSDLMLWSD 203 >5UIA-A nrPDB Length = 345 Score = 32.2 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 8/76 (10%) Query: 191 VVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALV 250 ++ G+ + L +V A + +TK V NP+ + D+ I + H GA Sbjct: 175 IIEDLGIHTLDIARFILGDV-ATLTARTKRV------NPKIKGEDVATIL-LDHQNGATS 226 Query: 251 LVDNSIMSPVLSRPLE 266 +VD S + + + P Sbjct: 227 IVDVSYATKLGTEPFP 242 >4MJM-A nrPDB Length = 385 Score = 32.2 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 48/146 (32%), Gaps = 30/146 (20%) Query: 151 AFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEV 210 A++ + L+K + + D +G S ++ +V V K + + Sbjct: 122 GAAVGVTADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKE---VRAKYPSLNIIAG- 177 Query: 211 AAAIGPQTKLVWLESPTN----------------------PRQQISDIRKISEMAHAQGA 248 A TK + +E+ N P+ + + A G Sbjct: 178 NVATAEATKAL-IEAGANVVKVGIGPGSICTTRVVAGVGVPQLTA--VYDCATEARKHGI 234 Query: 249 LVLVDNSIM-SPVLSRPLELGADIVM 273 V+ D I S + + L GA +VM Sbjct: 235 PVIADGGIKYSGDMVKALAAGAHVVM 260 >3TSB-A nrPDB Length = 511 Score = 32.2 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 48/146 (32%), Gaps = 30/146 (20%) Query: 151 AFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEV 210 A++ + L+K + + D +G S ++ +V V K + + Sbjct: 248 GAAVGVTADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKE---VRAKYPSLNIIAG- 303 Query: 211 AAAIGPQTKLVWLESPTN----------------------PRQQISDIRKISEMAHAQGA 248 A TK + +E+ N P+ + + A G Sbjct: 304 NVATAEATKAL-IEAGANVVKVGIGPGSICTTRVVAGVGVPQLTA--VYDCATEARKHGI 360 Query: 249 LVLVDNSIM-SPVLSRPLELGADIVM 273 V+ D I S + + L GA +VM Sbjct: 361 PVIADGGIKYSGDMVKALAAGAHVVM 386 >3RUY-A nrPDB Length = 392 Score = 32.2 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 37/109 (33%), Gaps = 28/109 (25%) Query: 140 SLLAKLDKADRAFCFTSGMAALSAVTHLIKN------------GEEIVAGDDVYGGSD-- 185 +AKL + +G A+ + E IV D+ +G + Sbjct: 85 EKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGA 144 Query: 186 ----------RLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLE 224 R ++P G++V + L+ + AAI P T LE Sbjct: 145 VSMSSNEEYKRGFGPMLP--GIIV--IPYGDLEALKAAITPNTAAFILE 189 >3ELE-A nrPDB Length = 398 Score = 31.9 bits (71), Expect = 0.66, Method: Composition-based stats. Identities = 37/228 (16%), Positives = 72/228 (31%), Gaps = 46/228 (20%) Query: 206 KLDEVAAAIGPQTKLVWLESPTNPRQQISD---IRKISEMAHAQG------ALVLVDN-- 254 D + I T+ V + SP NP + I+K+S++ + ++ D Sbjct: 161 DFDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPY 220 Query: 255 ----------SIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYF 304 ++ L V +S +K ++ + + VL E+Y Sbjct: 221 REIVYDGIKVPFVTKYYDNTL------VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYA 274 Query: 305 LQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHP 364 G L ++C + +K + ++++ + + Y GL Sbjct: 275 AVCGAGRALG----YVCAPSL------FQKMIVKCQGATGDINAYKENRDLLYEGL-TRI 323 Query: 365 GHHLHFSQAKGAGSVFSFITGSVALSKHLVETTK----YFSIAVSFGS 408 G+H G+ + F+ S E K A FG Sbjct: 324 GYHCFKPD----GAFYMFVKALEDDSNAFCEKAKEEDVLIVAADGFGC 367 >2PV7-A nrPDB Length = 298 Score = 31.5 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 22/55 (40%), Gaps = 1/55 (1%) Query: 181 YGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISD 235 YG L ++ + SG + ++ VA +I +V + P N + + Sbjct: 30 YGKLGGLFARYLRASGYPISILDREDW-AVAESILANADVVIVSVPINLTLETIE 83 >6HBE-A nrPDB Length = 451 Score = 31.5 bits (70), Expect = 0.91, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 37/86 (43%), Gaps = 10/86 (11%) Query: 184 SDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMA 243 + + + G++ + + ++ EV A P K E P + +++ D ++ Sbjct: 266 THVFGTAIKGALGILRAKKDAPRIPEVRAEGVPGVK----EIPAS-AKRVVDPYGLASPG 320 Query: 244 HAQGALVLVDNSIMSPVLSRPLELGA 269 H V +D P L++P+ +GA Sbjct: 321 HEHTVRVPLD-----PALAQPVAVGA 341 >4QJ1-A nrPDB Length = 361 Score = 31.5 bits (70), Expect = 0.91, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 61/170 (35%), Gaps = 36/170 (21%) Query: 167 LIKNGEEIVAGDDVYGGSDRLL---SQVVPRSGVVVKRVNTTKLDEVAAAIGP------- 216 L++ G +++ D +G S ++ ++ + + V N + I Sbjct: 113 LVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKV 172 Query: 217 --------QTKLVW-LESPTNPRQQISDIRKISEMAHAQGALVLVDNSI-MSPVLSRPLE 266 T++V + P QI+ I K S +A G ++ D I S + + L Sbjct: 173 GIGPGSICTTRIVAGVGVP-----QITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALA 227 Query: 267 LGADIVMHSATKFIAGHSDVMAGV--LAVKGEKLAKEVYFLQNSEGSGLA 314 +GA VM ++AG + E + VY GS A Sbjct: 228 VGASSVMI---------GSILAGTEESPGEKELIGDTVYKYYRGMGSVGA 268 >3FFS-A nrPDB Length = 400 Score = 31.5 bits (70), Expect = 0.91, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 61/170 (35%), Gaps = 36/170 (21%) Query: 167 LIKNGEEIVAGDDVYGGSDRLL---SQVVPRSGVVVKRVNTTKLDEVAAAIGP------- 216 L++ G +++ D +G S ++ ++ + + V N + I Sbjct: 152 LVEAGVDVIVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVVTEEATKELIENGADGIKV 211 Query: 217 --------QTKLVW-LESPTNPRQQISDIRKISEMAHAQGALVLVDNSI-MSPVLSRPLE 266 T++V + P QI+ I K S +A G ++ D I S + + L Sbjct: 212 GIGPGSICTTRIVAGVGVP-----QITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALA 266 Query: 267 LGADIVMHSATKFIAGHSDVMAGV--LAVKGEKLAKEVYFLQNSEGSGLA 314 +GA VM ++AG + E + VY GS A Sbjct: 267 VGASSVMI---------GSILAGTEESPGEKELIGDTVYKYYRGMGSVGA 307 >3NX3-A nrPDB Length = 395 Score = 31.1 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 24/61 (39%), Gaps = 8/61 (13%) Query: 199 VKRVNTTKLDEVAAAIGPQTKLVWLESPT-----NPRQQISDI-RKISEMAHAQGALVLV 252 VK + V + +T + LES NP + D + + ++ + L++ Sbjct: 161 VKFAKYNDISSVEKLVNEKTCAIILESVQGEGGINPANK--DFYKALRKLCDEKDILLIA 218 Query: 253 D 253 D Sbjct: 219 D 219 >3AII-A nrPDB Length = 553 Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 35/120 (29%), Gaps = 7/120 (5%) Query: 350 PRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSF--- 406 P +V PDHP + + G V+ L++ Sbjct: 419 PGPVRVERPLHPDHP--EIGNRVLELRGEVYLPGDDLGEGPLRLIDAVNVIYSGGELRYH 476 Query: 407 -GSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIE-DVDDLISDLDIAFKTFPL 464 ++ + M H EA + D R+ IE D +L D + + F Sbjct: 477 SEGIEEARELGASMIHWVPAESALEAEVIMPDASRVRGVIEADASELEVDDVVQLERFGF 536 >3EZS-A nrPDB Length = 376 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 22/106 (20%), Positives = 41/106 (38%), Gaps = 19/106 (17%) Query: 216 PQTKLVWLESPTNPRQQISDIRKI---SEMAHAQGALVLVD--------NSIMSPVLSRP 264 + LV L SP NP + + ++ ++A +++ D N+ P L Sbjct: 153 QEVDLVILNSPNNPTGRTLSLEELISWVKLALKHDFILINDECYSEIYENT-PPPSLLEA 211 Query: 265 LELGAD------IVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYF 304 L + +V+HS +K + + +G +A L K F Sbjct: 212 CMLAGNEAFKNVLVIHSLSKRSSAPG-LRSGFIAGDSRLLEKYKAF 256 >1UU1-A nrPDB Length = 335 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 48/122 (39%), Gaps = 6/122 (4%) Query: 133 PTRDALESLLAKLD-KADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQV 191 P + +E +L+ LD + G A + ++ + V Y R+ ++ Sbjct: 57 PDEELIEKILSYLDTDFLSKNNVSVGNGADEIIYVMMLMFDRSVFFPPTYSC-YRIFAKA 115 Query: 192 VPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL 251 V + V ++ EV G +V++ +P NP + + +I + GA V Sbjct: 116 VGAKFLEVPLTKDLRIPEVNVGEGD---VVFIPNPNNPTGHVFEREEIERIL-KTGAFVA 171 Query: 252 VD 253 +D Sbjct: 172 LD 173 >6JEQ-A nrPDB Length = 675 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 19/28 (67%) Query: 226 PTNPRQQISDIRKISEMAHAQGALVLVD 253 P NP +I +++++ + HA+G V++D Sbjct: 252 PHNPAARILELKRLIQKLHARGLRVIMD 279 >1T6J-A nrPDB Length = 716 Score = 30.3 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 14/99 (14%), Positives = 34/99 (34%), Gaps = 7/99 (7%) Query: 271 IVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIK-TMA 329 + ++ T G +D + ++ G + FD + RG++ ++ Sbjct: 107 MSVYGVTTGFGGSADT-----RTEDAISLQKALLEHQLCGVLPSSFDSFRLGRGLENSLP 161 Query: 330 LRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHL 368 L + + ++ H V+ V L + H + Sbjct: 162 LEVVRGAMT-IRVNSLTRGHSAVRLVVLEALTNFLNHGI 199 >4DUT-A nrPDB Length = 145 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 39/110 (35%), Gaps = 15/110 (13%) Query: 124 PYDYTRSGNPTRDALESLLAKLDKADRAFCFTSG------------MAALSAVTHLIKNG 171 Y+R N + + +A L +AD + M + + +++ Sbjct: 25 GQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVEFMISGPVMIQVLEGE 84 Query: 172 EEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLV 221 + I+ D+ G +D + + + ++ + V + P+T V Sbjct: 85 DAILKNRDLMGATD---PKKAEKGTIRADFADSIDANAVHGSDAPETARV 131 >3EI8-A nrPDB Length = 432 Score = 29.9 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 24/44 (54%), Gaps = 3/44 (6%) Query: 217 QTKLVWLESPTNPRQQISDIRKISEM---AHAQGALVLVDNSIM 257 +T +++ SP NP + +++++ A G++++ D++ Sbjct: 198 RTDIIFFCSPNNPTGAAATREQLTQLVEFAKKNGSIIVYDSAYA 241 >4RAS-A nrPDB Length = 704 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 234 SDIRKISEMAHAQGALVLVDNSIMSPVLSRPLELGA 269 D+ +++ A G +VD +++P L R LG Sbjct: 177 VDLARLAVRA---GLARVVDGVLVAPFLRRGFRLGV 209 >5VOO-A nrPDB Length = 296 Score = 29.5 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 2/66 (3%) Query: 187 LLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQ 246 LL + V V V++T + + A+ V L S N + +++ +A A Sbjct: 76 LLPHLATALTVPV-MVDSTSPEAMELALKYLPGRVLLNS-ANLEDGLERFDRVASLAKAH 133 Query: 247 GALVLV 252 GA ++V Sbjct: 134 GAALVV 139 >6C3C-A nrPDB Length = 413 Score = 29.5 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 30/97 (30%), Gaps = 11/97 (11%) Query: 179 DVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEV-----AAAIGPQTKLVWLESPTNPR-QQ 232 + L V+ V + ++ + +V +T ++L P NP Sbjct: 133 TLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDRIYPELERRVRTDALFLVDPNNPTGFS 192 Query: 233 IS-----DIRKISEMAHAQGALVLVDNSIMSPVLSRP 264 + ++ L+L+D S L P Sbjct: 193 LLRHGRKGFEEVVRFCKDHDKLLLIDFCFASFTLFEP 229 >3QYQ-A nrPDB Length = 293 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 6/36 (16%), Positives = 14/36 (38%), Gaps = 4/36 (11%) Query: 141 LLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVA 176 +A L+ +SG+ A A + +++ Sbjct: 173 AVAALEGGADFLQTSSGLGATHATMFTV----HLIS 204 >3GET-A nrPDB Length = 365 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 32/87 (36%), Gaps = 10/87 (11%) Query: 182 GGSDRLLSQVVPRSGVVVKRVN--TTKLDEVAAAI---GPQTKLVWLESPTNPRQQISDI 236 G + + + G + T LDE + KL++L P NP + D Sbjct: 113 GVTFAMYEIYAKQCGAKCYKTQSITHNLDEFKKLYETHKDEIKLIFLCLPNNPLGECLDA 172 Query: 237 RKISEMAHA--QGALVLVD---NSIMS 258 + +E + LV++D N S Sbjct: 173 SEATEFIKGVNEDCLVVIDAAYNEFAS 199 >4LHD-A nrPDB Length = 983 Score = 29.2 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 29/72 (40%), Gaps = 2/72 (2%) Query: 202 VNTTKLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVLVD--NSIMSP 259 ++ L A G + + + P+ + I I ++ H G V +D N Sbjct: 648 IDVEDLTSKAEKYGDRLAALMVTYPSTHGVFEATIGTICDIVHRFGGEVYMDGANMNAQV 707 Query: 260 VLSRPLELGADI 271 L RP + GAD+ Sbjct: 708 GLCRPADFGADV 719 >4LIS-A nrPDB Length = 371 Score = 28.4 bits (62), Expect = 6.9, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 23/60 (38%), Gaps = 2/60 (3%) Query: 155 TSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRV--NTTKLDEVAA 212 +G L++ G ++V D++Y S L+++ SG + + T Sbjct: 11 GTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDK 70 >4MOP-A nrPDB Length = 633 Score = 28.4 bits (62), Expect = 6.9, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 24/67 (35%), Gaps = 4/67 (5%) Query: 332 IEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSK 391 + + QE+ I + P+V ++ HP H A G+V I + + Sbjct: 416 MMQHQEDPLPIP-FEDPEPQVTTLFQP---SHPWHTQIHRDAFSYGAVQQSIDSRLIVDW 471 Query: 392 HLVETTK 398 T+ Sbjct: 472 RFFGRTE 478 >3AHE-A nrPDB Length = 845 Score = 28.4 bits (62), Expect = 7.2, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 33/97 (34%), Gaps = 8/97 (8%) Query: 116 QPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAV-THLIKNGEEI 174 S + + PT L+ A+L+ + + S V L G+ Sbjct: 612 FKSTNKINAIFAGKQPAPTWVTLDEARAELEAGAAEWKWASNAENNDEVQVVLASAGD-- 669 Query: 175 VAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVA 211 V ++ SD L + G+ K VN L ++ Sbjct: 670 VPTQELMAASDAL-----NKMGIKFKVVNVVDLLKLQ 701 >2WVK-A nrPDB Length = 391 Score = 28.4 bits (62), Expect = 7.5, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 37/91 (40%), Gaps = 10/91 (10%) Query: 127 YTRSGNPTRDALESLLAKLDKADRAFC--FTSGMAALSAVTHL---IKNG-----EEIVA 176 Y R AL L+ + + +G A+S L + +G +E+V+ Sbjct: 218 YGRVSERNNRALNQLIGGVSGFETDVVKTANAGEHAMSLGLALRLPLASGYAVEPQELVS 277 Query: 177 GDDVYGGSDRLLSQVVPRSGVVVKRVNTTKL 207 ++YGG L + V + GV + ++ T Sbjct: 278 LLELYGGVFPLEDEEVLQHGVEIFQIETRNP 308 >5ZR1-C nrPDB Length = 616 Score = 28.4 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 18/42 (42%) Query: 79 MNIKEEASVSTLLVNLDNKFDPFDAMSTPLYQTATFKQPSAI 120 +N + +T L+ L D FD ++ L+ A F + Sbjct: 554 LNFIRKDPSNTKLLELAETPDAFDKVALILFMQAIFAFENMG 595 >3WLO-A nrPDB Length = 609 Score = 28.0 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 202 VNTTKLDEVAAAIGPQTKLVWLESP 226 V TT L+ V AA+ P T +V+ E+P Sbjct: 447 VGTTILEAVKAAVDPSTVVVFAENP 471 >5G2X-C nrPDB Length = 599 Score = 28.0 bits (61), Expect = 9.5, Method: Composition-based stats. Identities = 25/147 (17%), Positives = 49/147 (33%), Gaps = 36/147 (24%) Query: 310 GSGLAPF--DCWLCLRGIKTMALRIEKQQENARKIA-MYLSSHPRVKKVYY--------- 357 G L+P + +L + L+++ +E+ +I Y H +K++ + Sbjct: 214 GGILSPLLANIYLHELDKFVLQLKMKFDRESPERITPEYRELHNEIKRISHRLKKLEGEE 273 Query: 358 ---------------AGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYF-- 400 LP + + A + GS + + E K F Sbjct: 274 KAKVLLEYQEKRKRLPTLPCTSQTNKVLKYVRYADDFIISVKGSKEDCQWIKEQLKLFIH 333 Query: 401 -SIAVSFGSVKSLISMPCFMSHASIPA 426 + + K+LI +H+S PA Sbjct: 334 NKLKMELSEEKTLI------THSSQPA 354 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.143 0.406 Lambda K H 0.267 0.0443 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,569,827 Number of Sequences: 36641 Number of extensions: 772192 Number of successful extensions: 2713 Number of sequences better than 10.0: 172 Number of HSP's better than 10.0 without gapping: 104 Number of HSP's successfully gapped in prelim test: 121 Number of HSP's that attempted gapping in prelim test: 2395 Number of HSP's gapped (non-prelim): 246 length of query: 464 length of database: 10,336,785 effective HSP length: 100 effective length of query: 364 effective length of database: 6,672,685 effective search space: 2428857340 effective search space used: 2428857340 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.0 bits)