BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P53563 (233 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4QNQ-A nrPDB 481 e-137 2BZW-A nrPDB 435 e-123 3ZK6-A nrPDB 327 3e-90 2PON-B nrPDB 297 3e-81 4QVX-A nrPDB 276 5e-75 4C5D-A nrPDB 264 2e-71 2O2N-A nrPDB 256 9e-69 4IEH-A nrPDB 194 2e-50 2XA0-A nrPDB 174 2e-44 2W3L-A nrPDB 166 8e-42 4K5A-A nrPDB 159 7e-40 2O2F-A nrPDB 159 1e-39 4CIM-A nrPDB 154 2e-38 5W63-A nrPDB 67 7e-12 6FBX-A nrPDB 66 1e-11 5W62-A nrPDB 66 1e-11 2JCN-A nrPDB 66 2e-11 5W61-A nrPDB 64 6e-11 4BD6-A nrPDB 64 7e-11 5W5Z-A nrPDB 64 8e-11 6CKV-A nrPDB 59 2e-09 1WSX-A nrPDB 59 2e-09 2VOG-A nrPDB 58 4e-09 5KTG-A nrPDB 57 7e-09 5WDD-A nrPDB 56 1e-08 4WMS-A nrPDB 54 5e-08 3PK1-A nrPDB 54 5e-08 3IO9-A nrPDB 54 5e-08 4U2V-B nrPDB 54 7e-08 5JSB-A nrPDB 54 7e-08 5TWA-A nrPDB 52 2e-07 3I1H-A nrPDB 50 6e-07 5UA4-A nrPDB 46 1e-05 2A5Y-A nrPDB 42 3e-04 1TY4-A nrPDB 40 7e-04 3QBR-A nrPDB 39 0.002 4B4S-A nrPDB 36 0.016 4BDU-A nrPDB 33 0.072 1KNW-A nrPDB 32 0.21 5TZP-A nrPDB 32 0.29 1H4S-A nrPDB 32 0.30 5WOS-A nrPDB 31 0.57 4MI8-A nrPDB 30 0.63 2IVE-A nrPDB 30 0.84 5VMN-A nrPDB 29 1.4 6N9M-A nrPDB 29 1.7 4LR8-A nrPDB 28 3.6 6CBN-A nrPDB 27 7.3 4BPY-A nrPDB 27 7.8 4XFJ-A nrPDB 27 8.1 >4QNQ-A nrPDB Length = 240 Score = 481 bits (1239), Expect = e-137, Method: Compositional matrix adjust. Identities = 233/233 (100%), Positives = 233/233 (100%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA Sbjct: 8 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 67 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 68 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 127 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP Sbjct: 128 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 187 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 233 WIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK Sbjct: 188 WIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 240 >2BZW-A nrPDB Length = 211 Score = 435 bits (1119), Expect = e-123, Method: Compositional matrix adjust. Identities = 210/211 (99%), Positives = 210/211 (99%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETE ERETPSAINGNPSWHLA Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEAERETPSAINGNPSWHLA 60 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP Sbjct: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERFN 211 WIQENGGWDTFVDLYGNNAAAESRKGQERFN Sbjct: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERFN 211 >3ZK6-A nrPDB Length = 181 Score = 327 bits (837), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 166/210 (79%), Positives = 168/210 (80%), Gaps = 40/210 (19%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPE Sbjct: 5 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEG-------------------- 44 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 IPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 45 --------------------IPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 84 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEP Sbjct: 85 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP 144 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERF 210 WIQENGGWDTFV+LYGNNAAAESRKGQER Sbjct: 145 WIQENGGWDTFVELYGNNAAAESRKGQERL 174 >2PON-B nrPDB Length = 156 Score = 297 bits (760), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 152/196 (77%), Positives = 154/196 (78%), Gaps = 40/196 (20%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPE TE E Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESE---------------- 44 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 45 ------------------------AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 80 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEP Sbjct: 81 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP 140 Query: 181 WIQENGGWDTFVDLYG 196 WIQENGGWDTFV+LYG Sbjct: 141 WIQENGGWDTFVELYG 156 >4QVX-A nrPDB Length = 167 Score = 276 bits (706), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 146/210 (69%), Positives = 151/210 (71%), Gaps = 50/210 (23%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQK Sbjct: 1 MSQSNRELVVDFLSYKLSQK---------------------------------------- 20 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 G+S+S MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 21 ---------GYSAS-GGGGGGGMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 70 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDK+MQVLVSRIA+WMATYLNDHLEP Sbjct: 71 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKKMQVLVSRIAAWMATYLNDHLEP 130 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERF 210 WIQENGGW TFV+LYGNNAAAESRKGQER Sbjct: 131 WIQENGGWATFVELYGNNAAAESRKGQERL 160 >4C5D-A nrPDB Length = 158 Score = 264 bits (674), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 125/127 (98%), Positives = 127/127 (100%) Query: 83 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVA 142 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVA Sbjct: 32 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVA 91 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAE 202 FFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEPWIQENGGWDTFV+LYGNNAAAE Sbjct: 92 FFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYGNNAAAE 151 Query: 203 SRKGQER 209 SRKGQER Sbjct: 152 SRKGQER 158 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 31/42 (73%), Positives = 35/42 (83%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETE 42 MSQSNRELVVDFLSYKLSQKGYSWSQ + V++ EA +E E Sbjct: 6 MSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFE 47 >2O2N-A nrPDB Length = 145 Score = 256 bits (653), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 134/195 (68%), Positives = 137/195 (70%), Gaps = 50/195 (25%) Query: 2 SQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLAD 61 SQSNRELVVDFLSYKLSQKGY Sbjct: 1 SQSNRELVVDFLSYKLSQKGY--------------------------------------- 21 Query: 62 SPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQ 121 S+ MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQ Sbjct: 22 -----------SAGGGGGGGGMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQ 70 Query: 122 SFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPW 181 SFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEPW Sbjct: 71 SFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPW 130 Query: 182 IQENGGWDTFVDLYG 196 IQENGGWDTFV+LYG Sbjct: 131 IQENGGWDTFVELYG 145 >4IEH-A nrPDB Length = 169 Score = 194 bits (494), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 99/192 (51%), Positives = 116/192 (60%), Gaps = 40/192 (20%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 NRE+V+ ++ YKLSQ+GY W DVEENRTEAPE TE E Sbjct: 14 NREIVMKYIHYKLSQRGYEWDAGDDVEENRTEAPEGTESE-------------------- 53 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 V LR+AGD+F RYRR F++++SQLH+TP TA F Sbjct: 54 --------------------VVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFA 93 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN HL WIQ+ Sbjct: 94 TVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQD 153 Query: 185 NGGWDTFVDLYG 196 NGGWD FV+LYG Sbjct: 154 NGGWDAFVELYG 165 >2XA0-A nrPDB Length = 207 Score = 174 bits (442), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 96/197 (48%), Positives = 121/197 (61%), Gaps = 9/197 (4%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPE-----ETEPERETPSAINGNPSWHL 59 NRE+V+ ++ YKLSQ+GY W DV A ++P A + +P Sbjct: 11 NREIVMKYIHYKLSQRGYEWDA-GDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPV--A 67 Query: 60 ADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTA 119 SP A +++ A +P V LR+AGD+F RYRR F++++SQLH+TP TA Sbjct: 68 RTSPLQTPAAPGAAAGPALSPVP-PVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTA 126 Query: 120 YQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLE 179 F VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN HL Sbjct: 127 RGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLH 186 Query: 180 PWIQENGGWDTFVDLYG 196 WIQ+NGGWD FV+LYG Sbjct: 187 TWIQDNGGWDAFVELYG 203 >2W3L-A nrPDB Length = 144 Score = 166 bits (420), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 87/192 (45%), Positives = 105/192 (54%), Gaps = 53/192 (27%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 NRE+V+ ++ YKLSQ+GY W +D E Sbjct: 3 NREIVMKYIHYKLSQRGYEWDAGADSE--------------------------------- 29 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 V + LREAGD+F RYRR F++++S LH+TP TA F Sbjct: 30 --------------------VVHKTLREAGDDFSRRYRRDFAEMSSGLHLTPFTARGRFA 69 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN HL WIQ+ Sbjct: 70 TVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQD 129 Query: 185 NGGWDTFVDLYG 196 NGGWD FV+LYG Sbjct: 130 NGGWDAFVELYG 141 >4K5A-A nrPDB Length = 184 Score = 159 bits (403), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 86/204 (42%), Positives = 107/204 (52%), Gaps = 49/204 (24%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 R LV DF+ YKL QKGY P + PA Sbjct: 21 TRALVADFVGYKLRQKGY---------------------------VCGAGPG----EGPA 49 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 + + QA+R AGDEFE R+RR FSDL +QLH+TPG+A Q F Sbjct: 50 AD------------------PLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFT 91 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 QV +ELF+ G NWGR+VAFF FG ALC ESV+KEM+VLV ++ WM YL L WI Sbjct: 92 QVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEVLVGQVQEWMVAYLETRLADWIHS 151 Query: 185 NGGWDTFVDLYGNNAAAESRKGQE 208 +GGW F LYG+ A E+R+ +E Sbjct: 152 SGGWAEFTALYGDGALEEARRLRE 175 >2O2F-A nrPDB Length = 138 Score = 159 bits (401), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 73/112 (65%), Positives = 85/112 (75%) Query: 85 AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFF 144 V LR+AGD+F RYRR F++++SQLH+TP TA F VV ELFRDGVNWGRIVAFF Sbjct: 26 VVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFF 85 Query: 145 SFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYG 196 FGG +CVESV++EM LV IA WM YLN HL WIQ+NGGWD FV+LYG Sbjct: 86 EFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 137 Score = 34.7 bits (78), Expect = 0.033, Method: Compositional matrix adjust. Identities = 12/22 (54%), Positives = 18/22 (81%) Query: 5 NRELVVDFLSYKLSQKGYSWSQ 26 NRE+V+ ++ YKLSQ+GY W + Sbjct: 4 NREIVMKYIHYKLSQRGYEWDE 25 >4CIM-A nrPDB Length = 163 Score = 154 bits (390), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 86/202 (42%), Positives = 105/202 (51%), Gaps = 51/202 (25%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 R LV DF+ YKL QKGY Sbjct: 10 TRALVADFVGYKLRQKGY------------------------------------------ 27 Query: 65 VNGA-TGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSF 123 V+GA G + D + QALR GDEFE R+RR FSDL +QLH+TPG+A Q F Sbjct: 28 VSGAGPGEGPAADP--------LGQALRAIGDEFETRFRRTFSDLAAQLHVTPGSAQQRF 79 Query: 124 EQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQ 183 QV +ELF+ G NWGR+VAFF FG ALC ESV+KEM+ LV ++ WM YL L WI Sbjct: 80 TQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVEYLETRLADWIH 139 Query: 184 ENGGWDTFVDLYGNNAAAESRK 205 +GGW F LYG+ A E+R+ Sbjct: 140 SSGGWAEFTALYGDGALEEARR 161 >5W63-A nrPDB Length = 189 Score = 66.6 bits (161), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 38/115 (33%), Positives = 62/115 (53%), Gaps = 9/115 (7%) Query: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 + Q L++ GDE + + +R +D S L T + F +V E+F DG NWGR+VA Sbjct: 58 LAQYLQQIGDELDNNVDLQRMLAD--SALQPTK----EVFVKVAREIFSDGKFNWGRVVA 111 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 F F L +E++ ++ ++ I +W YL +H+ WI+E GGW+ +G Sbjct: 112 LFYFASRLVIEALLTKIPDIIRTIINWTLDYLREHVINWIREQGGWEGIQTYFGT 166 >6FBX-A nrPDB Length = 152 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 39/119 (32%), Positives = 61/119 (51%), Gaps = 3/119 (2%) Query: 82 PMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGT-AYQSFEQVVNELFRDG-VNWGR 139 P + +A+R E E ++R F L+ + T G + + V+ EL DG +NWGR Sbjct: 31 PPSESAEAMRYLAKEMEQQHRTKFRSLSQEFLDTCGADPSKCLQSVMRELVGDGKMNWGR 90 Query: 140 IVAFFSFGGALCVESVDK-EMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 +V+ F+F G L E + + E R+A +A YL + W+ ENGGW+ F + N Sbjct: 91 VVSIFTFTGVLASELLSRGENSEGSRRLAETIADYLGGEKQDWLVENGGWEGFCRFFHN 149 >5W62-A nrPDB Length = 192 Score = 65.9 bits (159), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 33/115 (28%), Positives = 61/115 (53%), Gaps = 9/115 (7%) Query: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 + ++LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA Sbjct: 59 LSESLRRIGDELDSNMELQRMIADVDTD------SPREVFFRVAADMFADGNFNWGRVVA 112 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 F F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 113 LFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 >2JCN-A nrPDB Length = 172 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 53/113 (46%), Gaps = 1/113 (0%) Query: 83 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVA 142 M V + L GD+ RY F + L T AY+ F ++ LF G+NWGR+VA Sbjct: 53 MGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVA 112 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDH-LEPWIQENGGWDTFVDL 194 FG L + + + ++ ++ ++ H + WI + GGW ++L Sbjct: 113 LLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIAQRGGWVAALNL 165 >5W61-A nrPDB Length = 194 Score = 63.9 bits (154), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 60/116 (51%), Gaps = 9/116 (7%) Query: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 + ++L+ GDE + + +R + + + + + F +V ++F DG NWGR+VA Sbjct: 59 LSESLKRIGDELDSNMELQRMIAAVDTD------SPREVFFRVAADMFSDGNFNWGRVVA 112 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNN 198 F F L ++++ ++ L+ I W +L + L WIQ+ GGWD + +G Sbjct: 113 LFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTG 168 >4BD6-A nrPDB Length = 174 Score = 63.5 bits (153), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 32/115 (27%), Positives = 60/115 (52%), Gaps = 9/115 (7%) Query: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 + ++L+ GDE + + +R + + + + + F +V ++F DG NWGR+VA Sbjct: 59 LSESLKRIGDELDSNMELQRMIAAVDTD------SPREVFFRVAADMFSDGNFNWGRVVA 112 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 F F L ++++ ++ L+ I W +L + L WIQ+ GGWD + +G Sbjct: 113 LFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGT 167 >5W5Z-A nrPDB Length = 163 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 59/116 (50%), Gaps = 9/116 (7%) Query: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 + ++L+ GDE + + +R + + + + F +V ++F DG NWGR+VA Sbjct: 28 LSESLKRIGDELDSNMELQRMIA------AVDTDSPREVFFRVAADMFSDGNFNWGRVVA 81 Query: 143 FFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNN 198 F F L ++++ ++ L+ I W +L + L WIQ+ GGWD + +G Sbjct: 82 LFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTG 137 >6CKV-A nrPDB Length = 158 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 27/109 (24%), Positives = 52/109 (47%), Gaps = 3/109 (2%) Query: 83 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGT---AYQSFEQVVNELFRDGVNWGR 139 +A V L GDE E+ + ++ QLHI+ + +F V +F G+ WG+ Sbjct: 44 LAEVAAVLLRLGDELEMIRPSVYRNVARQLHISLQSERVVTDAFLAVAGHIFSAGITWGK 103 Query: 140 IVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGW 188 +V+ ++ L V++V + +V + + ++ L W++ GGW Sbjct: 104 VVSLYAVAAGLAVDAVRQAQPAMVHALVDALGEFVRKTLATWLRRRGGW 152 >1WSX-A nrPDB Length = 162 Score = 58.5 bits (140), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 36/111 (32%), Positives = 57/111 (51%), Gaps = 5/111 (4%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSF 146 + LR GD + + AF + +L I +SF +V+ +F+DGV NWGRIV SF Sbjct: 46 ETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRVMVHVFKDGVTNWGRIVTLISF 105 Query: 147 GG--ALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLY 195 G A ++SV++E + +A + L W+ + GWD FV+ + Sbjct: 106 GAFVAKHLKSVNQES--FIEPLAETITDVLVRTKRDWLVKQRGWDGFVEFF 154 >2VOG-A nrPDB Length = 157 Score = 57.8 bits (138), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 31/83 (37%), Positives = 53/83 (63%), Gaps = 5/83 (6%) Query: 118 TAYQSFEQVVNELFRDGV-NWGRIVAFFSFGGALCVESVDKEMQVLVS---RIASWMATY 173 TA F QV+ + F DG+ NWGRIV F+FGG L + +++ + VS +++S++A + Sbjct: 71 TARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLKQEQIALDVSAYKQVSSFVAEF 130 Query: 174 LNDHLEPWIQENGGW-DTFVDLY 195 + ++ WI++NGGW D F+ + Sbjct: 131 IMNNTGEWIRQNGGWEDGFIKKF 153 >5KTG-A nrPDB Length = 311 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 39/70 (55%) Query: 83 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVA 142 + V + L GD+ RY F +L QL T G AY+ F ++ + LF+ G++WGR+VA Sbjct: 236 LGQVGRQLALIGDDICRRYDTEFQNLLEQLQPTAGNAYELFTKIASSLFKSGISWGRVVA 295 Query: 143 FFSFGGALCV 152 FG L + Sbjct: 296 LLGFGYRLAL 305 >5WDD-A nrPDB Length = 168 Score = 56.2 bits (134), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 40/186 (21%), Positives = 70/186 (37%), Gaps = 48/186 (25%) Query: 6 RELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAV 65 + L D+++ +L + G SWS+ PE TP P LA+ A+ Sbjct: 19 KALCRDYINSRLIRAGVSWSK----------------PEHNTPV-----PGGKLAEVSAI 57 Query: 66 NGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHIT---PGTAYQS 122 L GDE E + ++ QL+I+ + Sbjct: 58 ------------------------LLRLGDELEYIRPNVYRNIARQLNISLHSETVVTDA 93 Query: 123 FEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWI 182 F V ++F G+ WG++V+ ++ L V+ V +V I + ++ L W+ Sbjct: 94 FLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKTLVTWL 153 Query: 183 QENGGW 188 + GGW Sbjct: 154 KRRGGW 159 >4WMS-A nrPDB Length = 518 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSF 146 + LR GD + + AF + +L I +S +V+ +F DGV NWGRIV SF Sbjct: 408 ETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF 467 Query: 147 GGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLY 195 G + + + +A + L W+ + GWD FV+ + Sbjct: 468 GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 516 >3PK1-A nrPDB Length = 189 Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSF 146 + LR GD + + AF + +L I +S +V+ +F DGV NWGRIV SF Sbjct: 74 ETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF 133 Query: 147 GGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLY 195 G + + + +A + L W+ + GWD FV+ + Sbjct: 134 GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 182 >3IO9-A nrPDB Length = 162 Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSF 146 + LR GD + + AF + +L I +S +V+ +F DGV NWGRIV SF Sbjct: 46 ETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF 105 Query: 147 GGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLY 195 G + + + +A + L W+ + GWD FV+ + Sbjct: 106 GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 154 >4U2V-B nrPDB Length = 315 Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 34/71 (47%) Query: 83 MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVA 142 M V + L GD+ RY F + L T AY+ F ++ LF G+NWGR+VA Sbjct: 238 MGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVA 297 Query: 143 FFSFGGALCVE 153 FG L + Sbjct: 298 LLGFGYRLALH 308 >5JSB-A nrPDB Length = 179 Score = 53.5 bits (127), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 1/109 (0%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSF 146 + LR GD + + AF + +L I +S +V+ +F DGV NWGRIV SF Sbjct: 40 ETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF 99 Query: 147 GGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLY 195 G + + + +A + L W+ + GWD FV+ + Sbjct: 100 GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 148 >5TWA-A nrPDB Length = 187 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 37/79 (46%) Query: 114 ITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATY 173 +TP F +V F DGV+WGR++AF +F + + + + +W Sbjct: 97 VTPDNVESEFREVERRTFSDGVHWGRVIAFLAFSMSFAAYVNSRGIDGGAYSVFNWTLRV 156 Query: 174 LNDHLEPWIQENGGWDTFV 192 LND L +IQ GW F+ Sbjct: 157 LNDSLADFIQRENGWRGFI 175 >3I1H-A nrPDB Length = 161 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 48/80 (60%), Gaps = 4/80 (5%) Query: 114 ITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSFGGALCVESVDKEMQVLV---SRIASW 169 ++ TA F QV+ + F DG+ NWGRIV F+F G L + + +++ V I+ + Sbjct: 72 VSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYF 131 Query: 170 MATYLNDHLEPWIQENGGWD 189 +A ++ ++ WI++NGGW+ Sbjct: 132 VAEFIMNNTGEWIRQNGGWE 151 >5UA4-A nrPDB Length = 153 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Query: 123 FEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWI 182 F VV ELF+D +NWGRI F F + D L S + + ++ +L PW+ Sbjct: 75 FTGVVTELFKDLINWGRICGFIVFSAKMAKYCKDANNH-LESTVITTAYNFMKHNLLPWM 133 Query: 183 QENGGWDTFV 192 +GG + F+ Sbjct: 134 ISHGGQEEFL 143 >2A5Y-A nrPDB Length = 204 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/116 (25%), Positives = 55/116 (47%), Gaps = 11/116 (9%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVN-----ELFRDGVNWGRIVA 142 + +R G FE ++ F + QL P ++ ++ VV + + +++GR++ Sbjct: 67 EMMRVMGTIFEKKHAENFETFSEQLLAVPRISFSLYQDVVRTVGNAQTDQSPMSYGRLIG 126 Query: 143 FFSFGG---ALCVESVDKEMQVLVSRIASWMATYLNDHLE-PWIQENGGWDTFVDL 194 SFGG A +ESV E+Q V + + + ++ + W + N WD F+ L Sbjct: 127 LISFGGFVAAKMMESV--ELQGQVRNLFVYTSLFIKTRIRNNWKEHNRSWDDFMTL 180 >1TY4-A nrPDB Length = 170 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 25/114 (21%), Positives = 53/114 (46%), Gaps = 7/114 (6%) Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELF-----RDGVNWGRIVA 142 + +R G FE ++ F QL P ++ ++ VV + + +++GR++ Sbjct: 47 EMMRVMGTIFEKKHAENFETFCEQLLAVPRISFSPYQDVVRTVGNAQTDQCPMSYGRLIG 106 Query: 143 FFSFGGALCVESVDK-EMQVLVSRIASWMATYLNDHLE-PWIQENGGWDTFVDL 194 SFGG + + ++ E+Q V + + + ++ + W + N WD F+ L Sbjct: 107 LISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRSWDDFMTL 160 >3QBR-A nrPDB Length = 179 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Query: 123 FEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWI 182 + +++N LF + +NWGRIVA F+F L + + + + Y ++ L+ WI Sbjct: 106 YLEILNGLF-EKLNWGRIVAMFAFLRILVLRLSKHGHSDAIQMLIKTTSQYSDEKLKNWI 164 Query: 183 QENGGWDTFVDLYG 196 + GW ++ G Sbjct: 165 NLHDGWSGLIEFSG 178 >4B4S-A nrPDB Length = 175 Score = 35.8 bits (81), Expect = 0.016, Method: Compositional matrix adjust. Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 27/134 (20%) Query: 82 PMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRD--GVNWGR 139 P AAV LR A +R FS PG ++ + + + D G WGR Sbjct: 36 PEAAV---LRSAAARLRQIHRSFFSAYLGY----PGNRFELVALMADSVLSDSPGPTWGR 88 Query: 140 IVAFFSFGGALC--------------VESVDKEMQVLVSRIASWMATYLNDHL----EPW 181 +V +F G L + KE + V+R + + L+ L W Sbjct: 89 VVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDSQRLVALLSSRLMGQHRAW 148 Query: 182 IQENGGWDTFVDLY 195 +Q GGWD F + Sbjct: 149 LQAQGGWDGFSHFF 162 >4BDU-A nrPDB Length = 311 Score = 33.5 bits (75), Expect = 0.072, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 9/73 (12%) Query: 86 VKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVA 142 + ++L+ GDE + + +R + + + + + F +V ++F DG NWGR+VA Sbjct: 242 LSESLKRIGDELDSNMELQRMIAAVDTD------SPREVFFRVAADMFSDGNFNWGRVVA 295 Query: 143 FFSFGGALCVESV 155 F F L ++++ Sbjct: 296 LFYFASKLVLKAL 308 >1KNW-A nrPDB Length = 425 Score = 32.0 bits (71), Expect = 0.21, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 6/54 (11%) Query: 111 QLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCV------ESVDKE 158 +HI G Y EQV + R + +G+ + S GG L V E+VD E Sbjct: 189 HMHIGSGVDYAHLEQVCGAMVRQVIEFGQDLQAISAGGGLSVPYQQGEEAVDTE 242 >5TZP-A nrPDB Length = 148 Score = 31.6 bits (70), Expect = 0.29, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 26/65 (40%), Gaps = 16/65 (24%) Query: 84 AAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAF 143 AA K ++ +EF++ R F +V ++ D +NWGRI+ Sbjct: 51 AACKSVIKTNYNEFDIIISRNID----------------FNVIVTQVLEDKINWGRIITI 94 Query: 144 FSFGG 148 +F Sbjct: 95 IAFCA 99 >1H4S-A nrPDB Length = 477 Score = 31.6 bits (70), Expect = 0.30, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 3/68 (4%) Query: 72 SSSLDAREVIPMAAVKQALREAGDEF-ELRYRRAFSDLTSQLHITPGTAYQSFEQVVNEL 130 +S L +E +P+AA+ +AL D F E YRRA + + H Y++F++ V E Sbjct: 363 ASRLGGKETLPLAALPEALPGKLDAFHEELYRRALA--FREDHTRKVDTYEAFKEAVQEG 420 Query: 131 FRDGVNWG 138 F + G Sbjct: 421 FALAFHCG 428 >5WOS-A nrPDB Length = 148 Score = 30.8 bits (68), Expect = 0.57, Method: Compositional matrix adjust. Identities = 13/65 (20%), Positives = 28/65 (43%) Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 ++V + D + WGR+++ +FG + +K +V + + L W+ + Sbjct: 80 EIVYDTIHDKITWGRVISIIAFGAYVTKVFKEKGRDNVVDLMPDIITESLLSRCRSWLSD 139 Query: 185 NGGWD 189 WD Sbjct: 140 QNCWD 144 >4MI8-A nrPDB Length = 143 Score = 30.4 bits (67), Expect = 0.63, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 11/73 (15%) Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATY--LNDHL 178 + ++ LF D +N GRIV FF G +C E V SW + LND + Sbjct: 70 RDLSKLFTSLFVDVINSGRIVGFFDVGRYVCEE---------VLCPGSWTEDHELLNDCM 120 Query: 179 EPWIQENGGWDTF 191 + EN + F Sbjct: 121 THFFIENNLMNHF 133 >2IVE-A nrPDB Length = 478 Score = 30.0 bits (66), Expect = 0.84, Method: Compositional matrix adjust. Identities = 13/51 (25%), Positives = 28/51 (54%), Gaps = 2/51 (3%) Query: 151 CVESVDKEMQVLVSRIASWM--ATYLNDHLEPWIQENGGWDTFVDLYGNNA 199 + + D +QVL+ +A+ + A ++ +E +E+GGW ++ +G A Sbjct: 229 ALSTFDGGLQVLIDALAASLGDAAHVGARVEGLAREDGGWRLIIEEHGRRA 279 >5VMN-A nrPDB Length = 132 Score = 29.3 bits (64), Expect = 1.4, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 125 QVVNELFRDG-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYL-NDHLEPWI 182 ++ N + DG +NWGRI+ +S + + ++I + + D + WI Sbjct: 55 EIGNNIVSDGNLNWGRILILLGISQLYFTKSESESER---TQITEQLERFFRQDAISNWI 111 Query: 183 QENGGWDTFVDL 194 NGGW T L Sbjct: 112 ASNGGWVTCASL 123 >6N9M-A nrPDB Length = 341 Score = 29.3 bits (64), Expect = 1.7, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 12/90 (13%) Query: 73 SSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFR 132 +SLDA + ++ A R ELR+ + + QL I + V + R Sbjct: 71 ASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPIA------GVVEAVIDGVR 124 Query: 133 DGVNW----GRIVAFFS--FGGALCVESVD 156 DG N R++ S FG A C++ +D Sbjct: 125 DGCNTFGVEARLIGIMSRTFGEAACLQELD 154 >4LR8-A nrPDB Length = 416 Score = 28.1 bits (61), Expect = 3.6, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 21/38 (55%), Gaps = 2/38 (5%) Query: 71 HSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDL 108 H + RE +P+ A +++E G E L R+ F+D+ Sbjct: 356 HPGTDHTREYVPLLAYSPSMKEGGQELPL--RQTFADI 391 >6CBN-A nrPDB Length = 438 Score = 26.9 bits (58), Expect = 7.3, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 21/44 (47%) Query: 87 KQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNEL 130 ++A+REAGD F R+A D + + I + F EL Sbjct: 304 QRAVREAGDRFLRHARKALDDASLPVEIAGDGTFFQFVPATEEL 347 >4BPY-A nrPDB Length = 175 Score = 26.9 bits (58), Expect = 7.8, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 3/37 (8%) Query: 41 TEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDA 77 T+PER+TP+A+ W P + G TG ++ A Sbjct: 78 TDPERDTPAALG---KWLKGIDPQIVGLTGEFDTIQA 111 >4XFJ-A nrPDB Length = 408 Score = 26.9 bits (58), Expect = 8.1, Method: Compositional matrix adjust. Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 9/83 (10%) Query: 56 SWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDE----FELRYRRAFSDLTSQ 111 +W D V G S+D R V P+ A+++ R G++ ++ R + + Sbjct: 219 NWSTPDEVIVGFEQGVPVSIDGRSVTPLQAIEELNRRGGEQGVGRLDVVEDRLVGIKSRE 278 Query: 112 LHITPG-----TAYQSFEQVVNE 129 ++ PG TA+ E V E Sbjct: 279 IYEAPGAMVLITAHTELEHVTLE 301 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4QNQ-A nrPDB 347 2e-96 2BZW-A nrPDB 300 3e-82 3ZK6-A nrPDB 242 7e-65 2XA0-A nrPDB 219 6e-58 2PON-B nrPDB 217 2e-57 4QVX-A nrPDB 212 8e-56 4IEH-A nrPDB 204 3e-53 4C5D-A nrPDB 196 8e-51 2O2N-A nrPDB 191 2e-49 2W3L-A nrPDB 184 4e-47 4K5A-A nrPDB 171 2e-43 4CIM-A nrPDB 171 3e-43 2O2F-A nrPDB 167 4e-42 2JCN-A nrPDB 135 2e-32 5WDD-A nrPDB 133 6e-32 4WMS-A nrPDB 130 5e-31 1WSX-A nrPDB 129 1e-30 3PK1-A nrPDB 128 1e-30 3IO9-A nrPDB 127 5e-30 5JSB-A nrPDB 127 5e-30 6FBX-A nrPDB 125 1e-29 5W61-A nrPDB 125 2e-29 5W62-A nrPDB 123 4e-29 4BD6-A nrPDB 123 9e-29 5W5Z-A nrPDB 122 9e-29 5W63-A nrPDB 121 3e-28 1TY4-A nrPDB 121 3e-28 6CKV-A nrPDB 119 9e-28 2A5Y-A nrPDB 117 7e-27 4U2V-B nrPDB 102 1e-22 2VOG-A nrPDB 100 7e-22 5KTG-A nrPDB 99 1e-21 3I1H-A nrPDB 97 5e-21 5TWA-A nrPDB 94 6e-20 3QBR-A nrPDB 92 2e-19 5UA4-A nrPDB 84 4e-17 Sequences not found previously or not previously below threshold: 4BDU-A nrPDB 70 7e-13 4B4S-A nrPDB 59 2e-09 5WOS-A nrPDB 53 1e-07 5TZP-A nrPDB 50 8e-07 2KUA-A nrPDB 45 2e-05 1K3K-A nrPDB 45 3e-05 5VMN-A nrPDB 42 3e-04 4MI8-A nrPDB 35 0.020 2XPX-A nrPDB 34 0.068 2Z1S-A nrPDB 31 0.37 2ESR-A nrPDB 31 0.40 3IT4-B nrPDB 30 0.83 3PUG-A nrPDB 30 0.84 4QJ3-A nrPDB 30 1.0 3GKQ-A nrPDB 29 1.5 4GXP-A nrPDB 28 3.0 >4QNQ-A nrPDB Length = 240 Score = 347 bits (889), Expect = 2e-96, Method: Composition-based stats. Identities = 233/233 (100%), Positives = 233/233 (100%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA Sbjct: 8 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 67 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 68 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 127 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP Sbjct: 128 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 187 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 233 WIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK Sbjct: 188 WIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK 240 >2BZW-A nrPDB Length = 211 Score = 300 bits (768), Expect = 3e-82, Method: Composition-based stats. Identities = 210/211 (99%), Positives = 210/211 (99%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETE ERETPSAINGNPSWHLA Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEAERETPSAINGNPSWHLA 60 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP Sbjct: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERFN 211 WIQENGGWDTFVDLYGNNAAAESRKGQERFN Sbjct: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERFN 211 >3ZK6-A nrPDB Length = 181 Score = 242 bits (618), Expect = 7e-65, Method: Composition-based stats. Identities = 166/210 (79%), Positives = 168/210 (80%), Gaps = 40/210 (19%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPE Sbjct: 5 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEG-------------------- 44 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 IPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 45 --------------------IPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 84 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEP Sbjct: 85 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP 144 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERF 210 WIQENGGWDTFV+LYGNNAAAESRKGQER Sbjct: 145 WIQENGGWDTFVELYGNNAAAESRKGQERL 174 >2XA0-A nrPDB Length = 207 Score = 219 bits (558), Expect = 6e-58, Method: Composition-based stats. Identities = 95/196 (48%), Positives = 120/196 (61%), Gaps = 7/196 (3%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPE----ETEPERETPSAINGNPSWHLA 60 NRE+V+ ++ YKLSQ+GY W AP ++P A + +P Sbjct: 11 NREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPV--AR 68 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 SP A +++ A +P V LR+AGD+F RYRR F++++SQLH+TP TA Sbjct: 69 TSPLQTPAAPGAAAGPALSPVPP-VVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTAR 127 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 F VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN HL Sbjct: 128 GRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHT 187 Query: 181 WIQENGGWDTFVDLYG 196 WIQ+NGGWD FV+LYG Sbjct: 188 WIQDNGGWDAFVELYG 203 >2PON-B nrPDB Length = 156 Score = 217 bits (553), Expect = 2e-57, Method: Composition-based stats. Identities = 152/196 (77%), Positives = 154/196 (78%), Gaps = 40/196 (20%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPE TE E Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESE---------------- 44 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 45 ------------------------AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 80 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEP Sbjct: 81 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEP 140 Query: 181 WIQENGGWDTFVDLYG 196 WIQENGGWDTFV+LYG Sbjct: 141 WIQENGGWDTFVELYG 156 >4QVX-A nrPDB Length = 167 Score = 212 bits (540), Expect = 8e-56, Method: Composition-based stats. Identities = 146/210 (69%), Positives = 150/210 (71%), Gaps = 50/210 (23%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 MSQSNRELVVDFLSYKLSQKGYS Sbjct: 1 MSQSNRELVVDFLSYKLSQKGYS------------------------------------- 23 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 120 + MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY Sbjct: 24 -------------ASGGGGGGGMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAY 70 Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEP 180 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDK+MQVLVSRIA+WMATYLNDHLEP Sbjct: 71 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKKMQVLVSRIAAWMATYLNDHLEP 130 Query: 181 WIQENGGWDTFVDLYGNNAAAESRKGQERF 210 WIQENGGW TFV+LYGNNAAAESRKGQER Sbjct: 131 WIQENGGWATFVELYGNNAAAESRKGQERL 160 >4IEH-A nrPDB Length = 169 Score = 204 bits (518), Expect = 3e-53, Method: Composition-based stats. Identities = 99/192 (51%), Positives = 116/192 (60%), Gaps = 40/192 (20%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 NRE+V+ ++ YKLSQ+GY W DVEENRTEAPE TE E Sbjct: 14 NREIVMKYIHYKLSQRGYEWDAGDDVEENRTEAPEGTESE-------------------- 53 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 V LR+AGD+F RYRR F++++SQLH+TP TA F Sbjct: 54 --------------------VVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFA 93 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN HL WIQ+ Sbjct: 94 TVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQD 153 Query: 185 NGGWDTFVDLYG 196 NGGWD FV+LYG Sbjct: 154 NGGWDAFVELYG 165 >4C5D-A nrPDB Length = 158 Score = 196 bits (497), Expect = 8e-51, Method: Composition-based stats. Identities = 126/139 (90%), Positives = 129/139 (92%) Query: 71 HSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNEL 130 + S MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNEL Sbjct: 20 YKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNEL 79 Query: 131 FRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDT 190 FRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEPWIQENGGWDT Sbjct: 80 FRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDT 139 Query: 191 FVDLYGNNAAAESRKGQER 209 FV+LYGNNAAAESRKGQER Sbjct: 140 FVELYGNNAAAESRKGQER 158 >2O2N-A nrPDB Length = 145 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 134/195 (68%), Positives = 137/195 (70%), Gaps = 50/195 (25%) Query: 2 SQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLAD 61 SQSNRELVVDFLSYKLSQKGYS Sbjct: 1 SQSNRELVVDFLSYKLSQKGYS-------------------------------------- 22 Query: 62 SPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQ 121 + MAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQ Sbjct: 23 ------------AGGGGGGGGMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQ 70 Query: 122 SFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPW 181 SFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA+WMATYLNDHLEPW Sbjct: 71 SFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDHLEPW 130 Query: 182 IQENGGWDTFVDLYG 196 IQENGGWDTFV+LYG Sbjct: 131 IQENGGWDTFVELYG 145 >2W3L-A nrPDB Length = 144 Score = 184 bits (465), Expect = 4e-47, Method: Composition-based stats. Identities = 87/192 (45%), Positives = 105/192 (54%), Gaps = 53/192 (27%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 NRE+V+ ++ YKLSQ+GY W +D E Sbjct: 3 NREIVMKYIHYKLSQRGYEWDAGADSE--------------------------------- 29 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 V + LREAGD+F RYRR F++++S LH+TP TA F Sbjct: 30 --------------------VVHKTLREAGDDFSRRYRRDFAEMSSGLHLTPFTARGRFA 69 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN HL WIQ+ Sbjct: 70 TVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQD 129 Query: 185 NGGWDTFVDLYG 196 NGGWD FV+LYG Sbjct: 130 NGGWDAFVELYG 141 >4K5A-A nrPDB Length = 184 Score = 171 bits (433), Expect = 2e-43, Method: Composition-based stats. Identities = 86/204 (42%), Positives = 107/204 (52%), Gaps = 49/204 (24%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 R LV DF+ YKL QKGY P + PA Sbjct: 21 TRALVADFVGYKLRQKGY---------------------------VCGAGPG----EGPA 49 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 + + QA+R AGDEFE R+RR FSDL +QLH+TPG+A Q F Sbjct: 50 ADP------------------LHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFT 91 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 QV +ELF+ G NWGR+VAFF FG ALC ESV+KEM+VLV ++ WM YL L WI Sbjct: 92 QVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEVLVGQVQEWMVAYLETRLADWIHS 151 Query: 185 NGGWDTFVDLYGNNAAAESRKGQE 208 +GGW F LYG+ A E+R+ +E Sbjct: 152 SGGWAEFTALYGDGALEEARRLRE 175 >4CIM-A nrPDB Length = 163 Score = 171 bits (432), Expect = 3e-43, Method: Composition-based stats. Identities = 82/203 (40%), Positives = 101/203 (49%), Gaps = 49/203 (24%) Query: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPA 64 R LV DF+ YKL QKG Sbjct: 10 TRALVADFVGYKLRQKG------------------------------------------- 26 Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 + S E + QALR GDEFE R+RR FSDL +QLH+TPG+A Q F Sbjct: 27 ------YVSGAGPGEGPAADPLGQALRAIGDEFETRFRRTFSDLAAQLHVTPGSAQQRFT 80 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 QV +ELF+ G NWGR+VAFF FG ALC ESV+KEM+ LV ++ WM YL L WI Sbjct: 81 QVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVEYLETRLADWIHS 140 Query: 185 NGGWDTFVDLYGNNAAAESRKGQ 207 +GGW F LYG+ A E+R+ + Sbjct: 141 SGGWAEFTALYGDGALEEARRLR 163 >2O2F-A nrPDB Length = 138 Score = 167 bits (421), Expect = 4e-42, Method: Composition-based stats. Identities = 73/112 (65%), Positives = 85/112 (75%) Query: 85 AVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFF 144 V LR+AGD+F RYRR F++++SQLH+TP TA F VV ELFRDGVNWGRIVAFF Sbjct: 26 VVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFF 85 Query: 145 SFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYG 196 FGG +CVESV++EM LV IA WM YLN HL WIQ+NGGWD FV+LYG Sbjct: 86 EFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 137 >2JCN-A nrPDB Length = 172 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 2/135 (1%) Query: 65 VNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFE 124 A +L + M V + L GD+ RY F + L T AY+ F Sbjct: 35 AAPADPEMVTLPLQPSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFT 94 Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDH-LEPWIQ 183 ++ LF G+NWGR+VA FG L + + + ++ ++ ++ H + WI Sbjct: 95 KIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVDFMLHHCIARWIA 154 Query: 184 ENGGWDTFVDLYGNN 198 + GGW ++L GN Sbjct: 155 QRGGWVAALNL-GNG 168 >5WDD-A nrPDB Length = 168 Score = 133 bits (334), Expect = 6e-32, Method: Composition-based stats. Identities = 42/196 (21%), Positives = 74/196 (37%), Gaps = 49/196 (25%) Query: 1 MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLA 60 +SQ+ + L D+++ +L + G SWS+ PE TP P LA Sbjct: 15 VSQA-KALCRDYINSRLIRAGVSWSK----------------PEHNTPV-----PGGKLA 52 Query: 61 DSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHI---TPG 117 + A+ L GDE E + ++ QL+I + Sbjct: 53 EVSAI------------------------LLRLGDELEYIRPNVYRNIARQLNISLHSET 88 Query: 118 TAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDH 177 +F V ++F G+ WG++V+ ++ L V+ V +V I + ++ Sbjct: 89 VVTDAFLAVAAQIFTAGITWGKVVSLYAVAAGLAVDCVRHAQPAMVHTIVDCLGEFVRKT 148 Query: 178 LEPWIQENGGWDTFVD 193 L W++ GGW Sbjct: 149 LVTWLKRRGGWADITK 164 >4WMS-A nrPDB Length = 518 Score = 130 bits (326), Expect = 5e-31, Method: Composition-based stats. Identities = 35/131 (26%), Positives = 55/131 (41%), Gaps = 8/131 (6%) Query: 74 SLDAREVIPMAAVK-------QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQV 126 + A + PM A + LR GD + + AF + +L I +S +V Sbjct: 387 ATGAADTAPMGASGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRV 446 Query: 127 VNELFRDGV-NWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQEN 185 + +F DGV NWGRIV SFG + + + +A + L W+ + Sbjct: 447 MIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQ 506 Query: 186 GGWDTFVDLYG 196 GWD FV+ + Sbjct: 507 RGWDGFVEFFH 517 >1WSX-A nrPDB Length = 162 Score = 129 bits (323), Expect = 1e-30, Method: Composition-based stats. Identities = 37/136 (27%), Positives = 56/136 (41%), Gaps = 2/136 (1%) Query: 68 ATGHSSSLDAREVIPMAAVK-QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQV 126 ATG S E + LR GD + + AF + +L I +SF +V Sbjct: 25 ATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEGDVKSFSRV 84 Query: 127 VNELFRDGV-NWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQEN 185 + +F+DGV NWGRIV SFG + + + +A + L W+ + Sbjct: 85 MVHVFKDGVTNWGRIVTLISFGAFVAKHLKSVNQESFIEPLAETITDVLVRTKRDWLVKQ 144 Query: 186 GGWDTFVDLYGNNAAA 201 GWD FV+ + Sbjct: 145 RGWDGFVEFFHVQDLE 160 >3PK1-A nrPDB Length = 189 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 62/170 (36%), Gaps = 8/170 (4%) Query: 35 TEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVK------- 87 + + + + + S + + A++ PM Sbjct: 14 RQHMDSPDLGTDDDDKAMADIGSLYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKAL 73 Query: 88 QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSF 146 + LR GD + + AF + +L I +S +V+ +F DGV NWGRIV SF Sbjct: 74 ETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISF 133 Query: 147 GGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYG 196 G + + + +A + L W+ + GWD FV+ + Sbjct: 134 GAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFH 183 >3IO9-A nrPDB Length = 162 Score = 127 bits (318), Expect = 5e-30, Method: Composition-based stats. Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 2/131 (1%) Query: 68 ATGHSSSLDAREVIPMAAVK-QALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQV 126 ATG S E + LR GD + + AF + +L I +S +V Sbjct: 25 ATGSKDSKPLGEAGAAGRRALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRV 84 Query: 127 VNELFRDGV-NWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQEN 185 + +F DGV NWGRIV SFG + + + +A + L W+ + Sbjct: 85 MIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQ 144 Query: 186 GGWDTFVDLYG 196 GWD FV+ + Sbjct: 145 RGWDGFVEFFH 155 >5JSB-A nrPDB Length = 179 Score = 127 bits (317), Expect = 5e-30, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 50/121 (41%), Gaps = 1/121 (0%) Query: 77 AREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGV- 135 R + LR GD + + AF + +L I +S +V+ +F DGV Sbjct: 29 GRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVT 88 Query: 136 NWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLY 195 NWGRIV SFG + + + +A + L W+ + GWD FV+ + Sbjct: 89 NWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFF 148 Query: 196 G 196 Sbjct: 149 H 149 >6FBX-A nrPDB Length = 152 Score = 125 bits (314), Expect = 1e-29, Method: Composition-based stats. Identities = 41/133 (30%), Positives = 65/133 (48%), Gaps = 3/133 (2%) Query: 68 ATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGT-AYQSFEQV 126 A + S + P + +A+R E E ++R F L+ + T G + + V Sbjct: 17 AEDYISFCSGIQQTPPSESAEAMRYLAKEMEQQHRTKFRSLSQEFLDTCGADPSKCLQSV 76 Query: 127 VNELFRDG-VNWGRIVAFFSFGGALCVESVDK-EMQVLVSRIASWMATYLNDHLEPWIQE 184 + EL DG +NWGR+V+ F+F G L E + + E R+A +A YL + W+ E Sbjct: 77 MRELVGDGKMNWGRVVSIFTFTGVLASELLSRGENSEGSRRLAETIADYLGGEKQDWLVE 136 Query: 185 NGGWDTFVDLYGN 197 NGGW+ F + N Sbjct: 137 NGGWEGFCRFFHN 149 >5W61-A nrPDB Length = 194 Score = 125 bits (312), Expect = 2e-29, Method: Composition-based stats. Identities = 36/173 (20%), Positives = 72/173 (41%), Gaps = 9/173 (5%) Query: 29 DVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQ 88 D + T E+ + + + + G + + + + Sbjct: 2 DGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSE 61 Query: 89 ALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFS 145 +L+ GDE + + +R + + + + + F +V ++F DG NWGR+VA F Sbjct: 62 SLKRIGDELDSNMELQRMIAAVDT------DSPREVFFRVAADMFSDGNFNWGRVVALFY 115 Query: 146 FGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNN 198 F L ++++ ++ L+ I W +L + L WIQ+ GGWD + +G Sbjct: 116 FASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTG 168 >5W62-A nrPDB Length = 192 Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 75/172 (43%), Gaps = 9/172 (5%) Query: 29 DVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQ 88 D + + T E+ + + + + G T + + + + Sbjct: 2 DGSGEQLGSGGPTSSEQIMKTGAFLLQGFIQDRAGRMAGETPELTLEQPPQDASTKKLSE 61 Query: 89 ALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFS 145 +LR GDE + + +R +D+ + + + F +V ++F DG NWGR+VA F Sbjct: 62 SLRRIGDELDSNMELQRMIADVDT------DSPREVFFRVAADMFADGNFNWGRVVALFY 115 Query: 146 FGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 F L ++++ ++ L+ I W +L + L WIQ+ GGW+ + +G Sbjct: 116 FASKLVLKALSTKVPELIRTIMGWTLDFLRERLLVWIQDQGGWEGLLSYFGT 167 >4BD6-A nrPDB Length = 174 Score = 123 bits (307), Expect = 9e-29, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 72/172 (41%), Gaps = 9/172 (5%) Query: 29 DVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQ 88 D + T E+ + + + + G + + + + Sbjct: 2 DGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSE 61 Query: 89 ALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFS 145 +L+ GDE + + +R + + + + + F +V ++F DG NWGR+VA F Sbjct: 62 SLKRIGDELDSNMELQRMIAAVDT------DSPREVFFRVAADMFSDGNFNWGRVVALFY 115 Query: 146 FGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 F L ++++ ++ L+ I W +L + L WIQ+ GGWD + +G Sbjct: 116 FASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGT 167 >5W5Z-A nrPDB Length = 163 Score = 122 bits (306), Expect = 9e-29, Method: Composition-based stats. Identities = 33/135 (24%), Positives = 63/135 (46%), Gaps = 9/135 (6%) Query: 67 GATGHSSSLDAREVIPMAAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFE 124 G + + + ++L+ GDE + + +R + + + + + F Sbjct: 9 GEAPELALDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDT------DSPREVFF 62 Query: 125 QVVNELFRDG-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQ 183 +V ++F DG NWGR+VA F F L ++++ ++ L+ I W +L + L WIQ Sbjct: 63 RVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQ 122 Query: 184 ENGGWDTFVDLYGNN 198 + GGWD + +G Sbjct: 123 DQGGWDGLLSYFGTG 137 >5W63-A nrPDB Length = 189 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 44/168 (26%), Positives = 73/168 (43%), Gaps = 22/168 (13%) Query: 60 ADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPG 117 + + H + Q L++ GDE + + +R +D S L T Sbjct: 32 RHGDSGTVVSRHELGGSELSDPTHKKLAQYLQQIGDELDNNVDLQRMLAD--SALQPT-- 87 Query: 118 TAYQSFEQVVNELFRDG-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLND 176 + F +V E+F DG NWGR+VA F F L +E++ ++ ++ I +W YL + Sbjct: 88 --KEVFVKVAREIFSDGKFNWGRVVALFYFASRLVIEALLTKIPDIIRTIINWTLDYLRE 145 Query: 177 HLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVV 224 H+ WI+E GGW+ +G W G+ +AGV+ Sbjct: 146 HVINWIREQGGWEGIQTYFGTPT-------------WKTVGVFLAGVL 180 >1TY4-A nrPDB Length = 170 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 54/127 (42%), Gaps = 7/127 (5%) Query: 75 LDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVN-----E 129 + + +R G FE ++ F QL P ++ ++ VV + Sbjct: 34 GAPGLPCGVQPEHEMMRVMGTIFEKKHAENFETFCEQLLAVPRISFSPYQDVVRTVGNAQ 93 Query: 130 LFRDGVNWGRIVAFFSFGGALCVESVDK-EMQVLVSRIASWMATYLNDHLE-PWIQENGG 187 + +++GR++ SFGG + + ++ E+Q V + + + ++ + W + N Sbjct: 94 TDQCPMSYGRLIGLISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRS 153 Query: 188 WDTFVDL 194 WD F+ L Sbjct: 154 WDDFMTL 160 >6CKV-A nrPDB Length = 158 Score = 119 bits (298), Expect = 9e-28, Method: Composition-based stats. Identities = 41/203 (20%), Positives = 74/203 (36%), Gaps = 56/203 (27%) Query: 1 MSQSNRELV-------VDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAING 53 MS +++ELV +++ +L + G SWS PER P Sbjct: 1 MSPTDKELVAQAKALGREYVHARLLRAGLSWSA----------------PERAAPV---- 40 Query: 54 NPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH 113 +A V L GDE E+ + ++ QLH Sbjct: 41 --------------------------PGRLAEVAAVLLRLGDELEMIRPSVYRNVARQLH 74 Query: 114 IT---PGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWM 170 I+ +F V +F G+ WG++V+ ++ L V++V + +V + + Sbjct: 75 ISLQSERVVTDAFLAVAGHIFSAGITWGKVVSLYAVAAGLAVDAVRQAQPAMVHALVDAL 134 Query: 171 ATYLNDHLEPWIQENGGWDTFVD 193 ++ L W++ GGW + Sbjct: 135 GEFVRKTLATWLRRRGGWTDVLK 157 >2A5Y-A nrPDB Length = 204 Score = 117 bits (291), Expect = 7e-27, Method: Composition-based stats. Identities = 28/145 (19%), Positives = 59/145 (40%), Gaps = 7/145 (4%) Query: 75 LDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVN-----E 129 + + +R G FE ++ F + QL P ++ ++ VV + Sbjct: 54 GAPGLPSGVQPEHEMMRVMGTIFEKKHAENFETFSEQLLAVPRISFSLYQDVVRTVGNAQ 113 Query: 130 LFRDGVNWGRIVAFFSFGGALCVESVDK-EMQVLVSRIASWMATYLNDHLE-PWIQENGG 187 + +++GR++ SFGG + + ++ E+Q V + + + ++ + W + N Sbjct: 114 TDQSPMSYGRLIGLISFGGFVAAKMMESVELQGQVRNLFVYTSLFIKTRIRNNWKEHNRS 173 Query: 188 WDTFVDLYGNNAAAESRKGQERFNR 212 WD F+ L R E+ R Sbjct: 174 WDDFMTLGKQMKEDYERAEAEKVGR 198 >4U2V-B nrPDB Length = 315 Score = 102 bits (253), Expect = 1e-22, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 37/88 (42%) Query: 73 SSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFR 132 ++ M V + L GD+ RY F + L T AY+ F ++ LF Sbjct: 228 TAAGITGSSTMGQVGRQLAIIGDDINRRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFE 287 Query: 133 DGVNWGRIVAFFSFGGALCVESVDKEMQ 160 G+NWGR+VA FG L + + Sbjct: 288 SGINWGRVVALLGFGYRLALHVYQHGLT 315 >2VOG-A nrPDB Length = 157 Score = 100 bits (247), Expect = 7e-22, Method: Composition-based stats. Identities = 38/153 (24%), Positives = 73/153 (47%), Gaps = 11/153 (7%) Query: 54 NPSWHLADSPAVNGATGHSSSLDAREVIP-----MAAVKQALREAGDEFELRYRRAFSDL 108 P +A+S ++ + L +P + + L+ + + Sbjct: 1 GPLGSMAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSY 60 Query: 109 TSQLHI-TPGTAYQSFEQVVNELFRDGV-NWGRIVAFFSFGGALCVESVDKEMQVLVS-- 164 H+ + TA F QV+ + F DG+ NWGRIV F+FGG L + +++ + VS Sbjct: 61 LDDFHVESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLKQEQIALDVSAY 120 Query: 165 -RIASWMATYLNDHLEPWIQENGGW-DTFVDLY 195 +++S++A ++ ++ WI++NGGW D F+ + Sbjct: 121 KQVSSFVAEFIMNNTGEWIRQNGGWEDGFIKKF 153 >5KTG-A nrPDB Length = 311 Score = 98.9 bits (244), Expect = 1e-21, Method: Composition-based stats. Identities = 26/87 (29%), Positives = 43/87 (49%) Query: 72 SSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELF 131 +++ + V + L GD+ RY F +L QL T G AY+ F ++ + LF Sbjct: 225 TAAGITGSNSILGQVGRQLALIGDDICRRYDTEFQNLLEQLQPTAGNAYELFTKIASSLF 284 Query: 132 RDGVNWGRIVAFFSFGGALCVESVDKE 158 + G++WGR+VA FG L + + Sbjct: 285 KSGISWGRVVALLGFGYRLALYVYQRG 311 >3I1H-A nrPDB Length = 161 Score = 97.4 bits (240), Expect = 5e-21, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 60/125 (48%), Gaps = 6/125 (4%) Query: 77 AREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHI-TPGTAYQSFEQVVNELFRDGV 135 + + + L+ + + +++ + TA F QV+ + F DG+ Sbjct: 34 PQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGI 93 Query: 136 -NWGRIVAFFSFGGALCVESVDKEMQVLVSR---IASWMATYLNDHLEPWIQENGGWD-T 190 NWGRIV F+F G L + + +++ V I+ ++A ++ ++ WI++NGGW+ Sbjct: 94 INWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENG 153 Query: 191 FVDLY 195 FV + Sbjct: 154 FVKKF 158 >5TWA-A nrPDB Length = 187 Score = 93.5 bits (230), Expect = 6e-20, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 1/94 (1%) Query: 102 RRAFSDLTSQ-LHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQ 160 R D +TP F +V F DGV+WGR++AF +F + + + Sbjct: 84 ERNVRDFRRGGWDVTPDNVESEFREVERRTFSDGVHWGRVIAFLAFSMSFAAYVNSRGID 143 Query: 161 VLVSRIASWMATYLNDHLEPWIQENGGWDTFVDL 194 + +W LND L +IQ GW F+ Sbjct: 144 GGAYSVFNWTLRVLNDSLADFIQRENGWRGFIVY 177 >3QBR-A nrPDB Length = 179 Score = 92.0 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 48/125 (38%), Gaps = 10/125 (8%) Query: 80 VIPMAAVKQALREAGDEFELRYRR--AFSDLTSQLHITPGTAYQS------FEQVVNELF 131 + L+ GD F R+ + + L I + +++N LF Sbjct: 56 PNGQEIIHSLLQLVGD-FNQRFSQTHEIEPVAQSLGIDSDKPVDKTALEIFYLEILNGLF 114 Query: 132 RDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTF 191 +NWGRIVA F+F L + + + + Y ++ L+ WI + GW Sbjct: 115 E-KLNWGRIVAMFAFLRILVLRLSKHGHSDAIQMLIKTTSQYSDEKLKNWINLHDGWSGL 173 Query: 192 VDLYG 196 ++ G Sbjct: 174 IEFSG 178 >5UA4-A nrPDB Length = 153 Score = 84.3 bits (206), Expect = 4e-17, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 123 FEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWI 182 F VV ELF+D +NWGRI F F + D L S + + ++ +L PW+ Sbjct: 75 FTGVVTELFKDLINWGRICGFIVFSAKMAKYCKDANNH-LESTVITTAYNFMKHNLLPWM 133 Query: 183 QENGGWDTFVDLY 195 +GG + F+ Sbjct: 134 ISHGGQEEFLAFS 146 >4BDU-A nrPDB Length = 311 Score = 70.4 bits (170), Expect = 7e-13, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 72 SSSLDAREVIPMAAVKQALREAGDEFE--LRYRRAFSDLTSQLHITPGTAYQSFEQVVNE 129 +++ + ++L+ GDE + + +R + + + + F +V + Sbjct: 228 TAAGITGSDASTKKLSESLKRIGDELDSNMELQRMIA------AVDTDSPREVFFRVAAD 281 Query: 130 LFRDG-VNWGRIVAFFSFGGALCVESVDKE 158 +F DG NWGR+VA F F L ++++ + Sbjct: 282 MFSDGNFNWGRVVALFYFASKLVLKALSTK 311 >4B4S-A nrPDB Length = 175 Score = 59.2 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 53/166 (31%), Gaps = 24/166 (14%) Query: 52 NGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQ 111 + +P + + + E P LR A +R FS Sbjct: 3 SADPLRERTELLLADYLGYSAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGY 62 Query: 112 LHITPGTAYQSFEQVVNELFRD--GVNWGRIVAFFSFGGALCVES--------------V 155 PG ++ + + + D G WGR+V +F G L Sbjct: 63 ----PGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPR 118 Query: 156 DKEMQVLV----SRIASWMATYLNDHLEPWIQENGGWDTFVDLYGN 197 KE + V R+ + +++ L W+Q GGWD F + Sbjct: 119 LKEQEGDVARDSQRLVALLSSRLMGQHRAWLQAQGGWDGFSHFFRT 164 >5WOS-A nrPDB Length = 148 Score = 53.1 bits (125), Expect = 1e-07, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 28/67 (41%) Query: 125 QVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 ++V + D + WGR+++ +FG + +K +V + + L W+ + Sbjct: 80 EIVYDTIHDKITWGRVISIIAFGAYVTKVFKEKGRDNVVDLMPDIITESLLSRCRSWLSD 139 Query: 185 NGGWDTF 191 WD Sbjct: 140 QNCWDGL 146 >5TZP-A nrPDB Length = 148 Score = 50.0 bits (117), Expect = 8e-07, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 27/76 (35%), Gaps = 2/76 (2%) Query: 123 FEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIA-SWMATYLNDHLEPW 181 F +V ++ D +NWGRI+ +F + I + + W Sbjct: 74 FNVIVTQVLEDKINWGRIITIIAFCAYYSKKVKQDTSPQYYDGIISEAITDAILSKYRSW 133 Query: 182 IQENGGWDTFVDLYGN 197 + W+ + +Y N Sbjct: 134 FIDQDYWNG-IRIYKN 148 >2KUA-A nrPDB Length = 170 Score = 45.4 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 29/163 (17%), Positives = 58/163 (35%), Gaps = 19/163 (11%) Query: 50 AINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLT 109 A + +P + + D E P + LR + + ++ FS Sbjct: 7 ADSQDPLHERTRRLLSDYIFFCAREPDTPEPPPTSVEAALLRSVTRQIQQEHQEFFSSFC 66 Query: 110 SQLHITPGTAYQSFEQVVNELFR--DGVNWGRIVAFFSFGGAL--------CVESVDKEM 159 + G + +Q+ ++L +W ++V +F G L + D Sbjct: 67 E----SRGNRLELVKQMADKLLSKDQDFSWSQLVMLLAFAGTLMNQGPYMAVKQKRDLGN 122 Query: 160 QVLVSR----IASWMATYLN-DHLEPWIQENGGWDTFVDLYGN 197 +V+V+R I +++ L ++ GGWD F + N Sbjct: 123 RVIVTRDCCLIVNFLYNLLMGRRHRARLEALGGWDGFCRFFKN 165 >1K3K-A nrPDB Length = 158 Score = 44.6 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 36/103 (34%), Gaps = 6/103 (5%) Query: 95 DEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDG-VNWGRIVAFFSFGGALCVE 153 F + + + T + ++ DG +NWGR +A +FG + + Sbjct: 41 TGLMRDKESLFEAMLANVRFHSTTGIDQLGLSMLQVSGDGNMNWGRALAILTFGSFVAQK 100 Query: 154 SVDKEMQVLVSRIASWMA-TYLNDHLEP-WIQENGGWDTFVDL 194 + + + A + Y + + P W + GGW Sbjct: 101 LSN---EPHLRDFALAVLPAYAYEAIGPQWFRARGGWRGLKAY 140 >5VMN-A nrPDB Length = 132 Score = 41.5 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 5/67 (7%) Query: 124 EQVVNELFRDG-VNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLN-DHLEPW 181 ++ N + DG +NWGRI+ G + E + ++I + + D + W Sbjct: 54 LEIGNNIVSDGNLNWGRILILL---GISQLYFTKSESESERTQITEQLERFFRQDAISNW 110 Query: 182 IQENGGW 188 I NGGW Sbjct: 111 IASNGGW 117 >4MI8-A nrPDB Length = 143 Score = 35.3 bits (79), Expect = 0.020, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 24/60 (40%), Gaps = 3/60 (5%) Query: 96 EFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESV 155 EF Y + + + ++ LF D +N GRIV FF G +C E + Sbjct: 48 EFRRHYDSVYR---ADYGPALKNWKRDLSKLFTSLFVDVINSGRIVGFFDVGRYVCEEVL 104 >2XPX-A nrPDB Length = 173 Score = 33.8 bits (75), Expect = 0.068, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 46/129 (35%), Gaps = 2/129 (1%) Query: 67 GATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQV 126 ++ + P V +E R F++ ++ F V Sbjct: 40 PVLELAARETPLRLSPEDTVVLRYHVLLEEIIERNSETFTETWNRFITHTEHVDLDFNSV 99 Query: 127 VNELFRDG-VNWGRIVAFFSFGGALCVE-SVDKEMQVLVSRIASWMATYLNDHLEPWIQE 184 E+F G + GR +A+ ++ C ++ V ++ ++ L+ WI + Sbjct: 100 FLEIFHRGDPSLGRALAWMAWCMHACRTLCCNQSTPYYVVDLSVRGMLEASEGLDGWIHQ 159 Query: 185 NGGWDTFVD 193 GGW T ++ Sbjct: 160 QGGWSTLIE 168 >2Z1S-A nrPDB Length = 454 Score = 31.1 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 12/86 (13%) Query: 135 VNWGRIV---AFFSFGGALCVE--SVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGW- 188 V W RI+ + G L E + E+ L+ + + L WI++ GGW Sbjct: 88 VAWPRIMPAAGIINEEGLLFYEHLLDEIELAGLIPMLTLYHWD-----LPQWIEDEGGWT 142 Query: 189 -DTFVDLYGNNAAAESRKGQERFNRW 213 + + A+ + ER N W Sbjct: 143 QRETIQHFKTYASVIMDRFGERINWW 168 >2ESR-A nrPDB Length = 177 Score = 31.1 bits (68), Expect = 0.40, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 135 VNWGRIVAFFSFGGALCVESVDKEMQVLV 163 N GR++ F+ G L +E+V + M V Sbjct: 30 FNGGRVLDLFAGSGGLAIEAVSRGMSAAV 58 >3IT4-B nrPDB Length = 205 Score = 30.0 bits (65), Expect = 0.83, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%), Gaps = 12/82 (14%) Query: 73 SSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLH------ITPGTAYQSFEQV 126 SS + A + +A+ D+ + + +T ++ T A + Q+ Sbjct: 48 SSGASEIPPAQADLDEAVLRVCDDLCAQLQADAEGVTKRVTVTVTGAATEDDALVAARQI 107 Query: 127 VNE------LFRDGVNWGRIVA 142 + LF NWGR++A Sbjct: 108 ARDSLVKTALFGSDPNWGRVLA 129 >3PUG-A nrPDB Length = 433 Score = 30.0 bits (65), Expect = 0.84, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 37/116 (31%), Gaps = 12/116 (10%) Query: 11 DFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATG 70 D LS + + GY D E + E + + + + A A Sbjct: 302 DRLSLEATDGGYELRVGGDARELTADELREELLGLTSYVPSMDDIVDSMEEFEAAKEA-- 359 Query: 71 HSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQV 126 R I M LR G E ++ R + + T Q +TP F+ V Sbjct: 360 ------GRGAIAMTQSA-TLRIGGTEIDIEKDRMWDEATYQAAMTP---ISLFQDV 405 >4QJ3-A nrPDB Length = 379 Score = 30.0 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 26/74 (35%), Gaps = 4/74 (5%) Query: 67 GATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHI----TPGTAYQS 122 T + A ++ + R DE E + RR D +L + T + + Sbjct: 15 PTTENLYFQGAAMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKST 74 Query: 123 FEQVVNELFRDGVN 136 F + + + G + Sbjct: 75 FIKQMRIIHGSGYS 88 >3GKQ-A nrPDB Length = 389 Score = 29.2 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 10/38 (26%), Positives = 18/38 (47%) Query: 175 NDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNR 212 +EP+ ++ GW V + A E R+ ++NR Sbjct: 338 RRSMEPFYADDRGWREEVLFESDRAIIEWRRLASQYNR 375 >4GXP-A nrPDB Length = 467 Score = 28.4 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 34/92 (36%), Gaps = 12/92 (13%) Query: 121 QSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLN----- 175 + ++++ L G+ V F + ++ +L IA W A Y Sbjct: 106 DFYNRIIDTLLEKGIT--PFVTIFHWDLPFALQLKG---GLLNREIADWFAEYSRVLFEN 160 Query: 176 --DHLEPWIQENGGWDTFVDLYGNNAAAESRK 205 D ++ WI N + + YG+ A R+ Sbjct: 161 FGDRVKNWITFNEPLCSAIPGYGSGTFAPGRQ 192 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.108 0.275 Lambda K H 0.267 0.0332 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,322,922 Number of Sequences: 36641 Number of extensions: 258343 Number of successful extensions: 913 Number of sequences better than 10.0: 52 Number of HSP's better than 10.0 without gapping: 87 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 757 Number of HSP's gapped (non-prelim): 137 length of query: 233 length of database: 10,336,785 effective HSP length: 94 effective length of query: 139 effective length of database: 6,892,531 effective search space: 958061809 effective search space used: 958061809 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 57 (26.9 bits)