BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P53042 (499 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4JA9-A nrPDB 1016 0.0 4ZVZ-A nrPDB 695 0.0 5JJT-A nrPDB 585 e-167 1A17-A nrPDB 330 7e-91 3ICF-A nrPDB 278 5e-75 5W0W-C nrPDB 227 9e-60 4ORC-A nrPDB 215 3e-56 4ORB-A nrPDB 212 3e-55 3V4Y-A nrPDB 212 3e-55 4IL1-A nrPDB 211 5e-55 1S70-A nrPDB 210 1e-54 5JPE-A nrPDB 184 7e-47 6FO1-G nrPDB 80 2e-15 4I2W-A nrPDB 63 2e-10 2C2L-A nrPDB 62 6e-10 2GW1-A nrPDB 60 3e-09 1QZ2-A nrPDB 53 3e-07 5OMP-A nrPDB 52 7e-07 1KT1-A nrPDB 50 2e-06 1IHG-A nrPDB 46 3e-05 5A01-A nrPDB 44 2e-04 5LVV-A nrPDB 43 3e-04 1G5B-A nrPDB 43 4e-04 1V73-A nrPDB 42 5e-04 4CGU-A nrPDB 41 0.001 1W3B-A nrPDB 39 0.005 5JHE-A nrPDB 37 0.013 5VJW-A nrPDB 37 0.015 2W42-A nrPDB 34 0.11 2IF4-A nrPDB 34 0.12 5G04-F nrPDB 33 0.28 2Y4T-A nrPDB 32 0.61 4OFZ-A nrPDB 30 2.2 4Z54-A nrPDB 30 2.3 6B85-J nrPDB 30 2.4 3D3U-A nrPDB 30 3.2 2J5A-A nrPDB 28 7.6 3KHX-A nrPDB 28 9.3 >4JA9-A nrPDB Length = 488 Score = 1016 bits (2628), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/484 (100%), Positives = 484/484 (100%) Query: 16 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 75 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT Sbjct: 5 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 64 Query: 76 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 135 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK Sbjct: 65 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 124 Query: 136 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLM 195 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLM Sbjct: 125 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLM 184 Query: 196 QWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFE 255 QWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFE Sbjct: 185 QWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFE 244 Query: 256 LNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF 315 LNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF Sbjct: 245 LNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF 304 Query: 316 EGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQP 375 EGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQP Sbjct: 305 EGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQP 364 Query: 376 PDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYE 435 PDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYE Sbjct: 365 PDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYE 424 Query: 436 VAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQ 495 VAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQ Sbjct: 425 VAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQ 484 Query: 496 LGMM 499 LGMM Sbjct: 485 LGMM 488 >4ZVZ-A nrPDB Length = 333 Score = 695 bits (1793), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/331 (98%), Positives = 329/331 (99%) Query: 169 SMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVE 228 SMTIEDEYSGPKLEDGKVTI+FMK+LMQWYKDQKKLHRKCAYQILVQVKEVL KLSTLVE Sbjct: 3 SMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVE 62 Query: 229 TTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFG 288 TTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFG Sbjct: 63 TTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFG 122 Query: 289 FKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKV 348 FKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKV Sbjct: 123 FKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKV 182 Query: 349 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGP 408 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS+SKRGVSCQFGP Sbjct: 183 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGP 242 Query: 409 DVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD 468 DVTKAFLEEN LDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD Sbjct: 243 DVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD 302 Query: 469 LRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 499 LRPQFHQFTAVPHPNVKPMAYANTLLQLGMM Sbjct: 303 LRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 333 >5JJT-A nrPDB Length = 479 Score = 585 bits (1507), Expect = e-167, Method: Compositional matrix adjust. Identities = 268/473 (56%), Positives = 359/473 (75%), Gaps = 1/473 (0%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGD 84 + RAEE K+QAN+ FK Y +AI Y++AIELN +NA+Y+ NR+ A+ + E YG A+ D Sbjct: 6 VSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQD 65 Query: 85 ATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVK 144 A++AIE+D +Y KGYYRR A+ +A+GKF+ AL+D++ V ++ PND DA K +EC K V Sbjct: 66 ASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKECEKAVM 125 Query: 145 QKAFERAIAGD-EHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKK 203 + FE AI+ RRSV +S+D ++ +E +YSG ++E +VT+ F+K +M+ +K+QK Sbjct: 126 KLKFEEAISVPVSERRSVAESIDFHTIEVEPQYSGARIEGEEVTLDFVKTMMEDFKNQKT 185 Query: 204 LHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSET 263 LH++ AYQI++Q +++L L +LV+ ++ + ITVCGD HGQFYDLLNIFELNGLPSE Sbjct: 186 LHKRYAYQIVLQTRQILLALPSLVDISVPHGKHITVCGDVHGQFYDLLNIFELNGLPSEE 245 Query: 264 NPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKY 323 NPY+FNGDFVDRGSFSVE+ILTLF FK + P +L RGNHE+ +MN+IYGFEGEV++K Sbjct: 246 NPYLFNGDFVDRGSFSVEIILTLFAFKCMCPSSIYLARGNHESKSMNKIYGFEGEVRSKL 305 Query: 324 TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCD 383 + + +LF+EVF +LPLA INGKV ++HGGLFS DGV L DIR I+R +PP+ G MC+ Sbjct: 306 SEKFVDLFAEVFCYLPLAHVINGKVFVVHGGLFSVDGVKLSDIRAIDRFCEPPEEGLMCE 365 Query: 384 LLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCV 443 LLWSDPQP GR SKRGV FG DVTK FL++N LD ++RSHEVK EGYEV H G+ + Sbjct: 366 LLWSDPQPLPGRGPSKRGVGLSFGGDVTKRFLQDNNLDLLVRSHEVKDEGYEVEHDGKLI 425 Query: 444 TVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQL 496 TVFSAPNYCDQMGNK ++I + D++P F+AVPHP+VKPMAYAN L++ Sbjct: 426 TVFSAPNYCDQMGNKGAFIRFEAPDMKPNIVTFSAVPHPDVKPMAYANNFLRM 478 >1A17-A nrPDB Length = 166 Score = 330 bits (847), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 161/166 (96%), Positives = 165/166 (99%) Query: 16 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 75 RDEPPA+G LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT Sbjct: 1 RDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 60 Query: 76 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 135 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP+DKDAKMK Sbjct: 61 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMK 120 Query: 136 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKL 181 YQEC+KIVKQKAFERAIAGDEH+RSVVDSLDIESMTIEDEYSGPKL Sbjct: 121 YQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKL 166 >3ICF-A nrPDB Length = 335 Score = 278 bits (710), Expect = 5e-75, Method: Compositional matrix adjust. Identities = 140/302 (46%), Positives = 186/302 (61%), Gaps = 12/302 (3%) Query: 202 KKLHRKCAYQILVQVKEVLCKLSTLVETTLKETE--KITVCGDTHGQFYDLLNIFELNGL 259 K L +K I+ + + ++VE T KI+VCGDTHGQFYD+LN+F G Sbjct: 29 KYLPKKYVAAIISHADTLFRQEPSMVELENNSTPDVKISVCGDTHGQFYDVLNLFRKFGK 88 Query: 260 PSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEV 319 + Y+FNGDFVDRGS+S EV L + K+L+P++F L RGNHE+DNMN+IYGFE E Sbjct: 89 VGPKHTYLFNGDFVDRGSWSCEVALLFYCLKILHPNNFFLNRGNHESDNMNKIYGFEDEC 148 Query: 320 KAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSG 379 K KY+ +++ +F++ FE LPLA IN L+MHGGL S+ TL D + I+R QPP G Sbjct: 149 KYKYSQRIFNMFAQSFESLPLATLINNDYLVMHGGLPSDPSATLSDFKNIDRFAQPPRDG 208 Query: 380 PMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHG 439 +LLW+DPQ NG S+RG+ FGPD+T FL N+L I RSHE++ G + Sbjct: 209 AFMELLWADPQEANGMGPSQRGLGHAFGPDITDRFLRNNKLRKIFRSHELRMGGVQFEQK 268 Query: 440 GRCVTVFSAPNYCDQMGNKASYIHL----------QGSDLRPQFHQFTAVPHPNVKPMAY 489 G+ +TVFSAPNYCD GN IH+ + D F AV HP++KPMAY Sbjct: 269 GKLMTVFSAPNYCDSQGNLGGVIHVVPGHGILQAGRNDDQNLIIETFEAVEHPDIKPMAY 328 Query: 490 AN 491 +N Sbjct: 329 SN 330 >5W0W-C nrPDB Length = 311 Score = 227 bits (579), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 119/296 (40%), Positives = 176/296 (59%), Gaps = 11/296 (3%) Query: 189 TFMKDLMQWYK---DQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHG 245 F K+L QW + + K+L + + KE+L K S + E +TVCGD HG Sbjct: 7 VFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCP----VTVCGDVHG 62 Query: 246 QFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHE 305 QF+DL+ +F + G +TN Y+F GD+VDRG +SVE + L K+ Y + +LRGNHE Sbjct: 63 QFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHE 121 Query: 306 TDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLD 364 + + Q+YGF E KY A +++ F+++F++LPL ++G++ +HGGL S TLD Sbjct: 122 SRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL-SPSIDTLD 180 Query: 365 DIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYII 424 IR ++R ++ P GPMCDLLWSDP + G +S RG FG D+++ F N L + Sbjct: 181 HIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVS 240 Query: 425 RSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVP 480 R+H++ EGY H VT+FSAPNYC + GN+A+ + L + L+ F QF P Sbjct: 241 RAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT-LKYSFLQFDPAP 295 >4ORC-A nrPDB Length = 544 Score = 215 bits (548), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 119/300 (39%), Positives = 173/300 (57%), Gaps = 22/300 (7%) Query: 201 QKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLP 260 + ++ + A +I+ + +L + T++E ITVCGD HGQF+DL+ +FE+ G P Sbjct: 82 EGRVDEEIALRIINEGAAILRREKTMIEVE----APITVCGDIHGQFFDLMKLFEVGGSP 137 Query: 261 SETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVK 320 + T Y+F GD+VDRG FS+E +L L+ K+LYP LLRGNHE ++ + + F+ E K Sbjct: 138 ANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECK 196 Query: 321 AKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGP 380 KY+ ++YE E F+ LPLA +N + L +HGGL S + TLDDIR+++R ++PP GP Sbjct: 197 IKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGL-SPEIHTLDDIRRLDRFKEPPAFGP 255 Query: 381 MCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAE 432 MCDLLWSDP G S+ RG S + FL+ N L IIR+HE + Sbjct: 256 MCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDA 315 Query: 433 GYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKP 486 GY + + +T+FSAPNY D NKA+ + + + + QF PHP P Sbjct: 316 GYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNCSPHPYWLP 373 >4ORB-A nrPDB Length = 519 Score = 212 bits (540), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 120/319 (37%), Positives = 179/319 (56%), Gaps = 27/319 (8%) Query: 183 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 38 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 89 Query: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 90 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148 Query: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E Sbjct: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN- 207 Query: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 413 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 208 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCD 267 Query: 414 FLEENQLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 467 FL+ N L I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327 Query: 468 DLRPQFHQFTAVPHPNVKP 486 + QF PHP P Sbjct: 328 VM--NIRQFNCSPHPYWLP 344 >3V4Y-A nrPDB Length = 306 Score = 212 bits (539), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 107/241 (44%), Positives = 152/241 (63%), Gaps = 4/241 (1%) Query: 226 LVETTLKETEK-ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVIL 284 L + L E E + +CGD HGQ+YDLL +FE G P E+N Y+F GD+VDRG S+E I Sbjct: 46 LSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESN-YLFLGDYVDRGKQSLETIC 104 Query: 285 TLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCI 344 L +K+ YP++F LLRGNHE ++N+IYGF E K +Y ++++ F++ F LP+A + Sbjct: 105 LLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIV 164 Query: 345 NGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSVSKRGVS 403 + K+ HGGL S D +++ IR+I R PD G +CDLLWSDP G + RGVS Sbjct: 165 DEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVS 223 Query: 404 CQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIH 463 FG +V FL ++ LD I R+H+V +GYE + VT+FSAPNYC + N + + Sbjct: 224 FTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMS 283 Query: 464 L 464 + Sbjct: 284 V 284 >4IL1-A nrPDB Length = 823 Score = 211 bits (538), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 120/319 (37%), Positives = 179/319 (56%), Gaps = 27/319 (8%) Query: 183 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 371 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 422 Query: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 423 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 481 Query: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL E Sbjct: 482 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEIN- 540 Query: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 413 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 541 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCD 600 Query: 414 FLEENQLDYIIRSHEVKAEGYEVAHGGRC------VTVFSAPNYCDQMGNKASYIHLQGS 467 FL+ N L I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 601 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 660 Query: 468 DLRPQFHQFTAVPHPNVKP 486 + QF PHP P Sbjct: 661 VM--NIRQFNCSPHPYWLP 677 >1S70-A nrPDB Length = 330 Score = 210 bits (535), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 114/268 (42%), Positives = 159/268 (59%), Gaps = 11/268 (4%) Query: 206 RKCAYQILVQVKEV----LCKLST---LVETTLKETEK-ITVCGDTHGQFYDLLNIFELN 257 R C +VQ+ E LC S L + L E E + +CGD HGQ+ DLL +FE Sbjct: 22 RGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYG 81 Query: 258 GLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEG 317 G P E N Y+F GD+VDRG S+E I L +K+ YP++F LLRGNHE ++N+IYGF Sbjct: 82 GFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYD 140 Query: 318 EVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPD 377 E K ++ ++++ F++ F LP+A ++ K+ HGGL S D +++ IR+I R PD Sbjct: 141 ECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPD 199 Query: 378 SGPMCDLLWSDPQPQ-NGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEV 436 +G +CDLLWSDP G + RGVS FG DV FL + LD I R+H+V +GYE Sbjct: 200 TGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEF 259 Query: 437 AHGGRCVTVFSAPNYCDQMGNKASYIHL 464 + VT+FSAPNYC + N + + Sbjct: 260 FAKRQLVTLFSAPNYCGEFDNAGGMMSV 287 >5JPE-A nrPDB Length = 311 Score = 184 bits (467), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 101/252 (40%), Positives = 144/252 (57%), Gaps = 7/252 (2%) Query: 212 ILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGD 271 I +E+ +L+E + V GD HGQ++DL+ IF G P +TN Y+F GD Sbjct: 36 ICASAREIFLSQPSLLELA----PPVKVVGDVHGQYHDLIRIFSKCGFPPKTN-YLFLGD 90 Query: 272 FVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELF 331 +V+RG S+E IL L +K+ YP++F LLRGNHE N+ ++YGF E K + + ++LF Sbjct: 91 YVNRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKTWKLF 150 Query: 332 SEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQP 391 + F LP+A + GK+ +HGGL S ++D+IR I R PD G + DLLWSDP Sbjct: 151 IDTFNTLPIAAIVAGKIFCVHGGL-SPVLNSMDEIRNIARPTDVPDFGLLNDLLWSDPAD 209 Query: 392 Q-NGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPN 450 N ++RGVS F FL + D + R+H V +GYE + VTVFSAPN Sbjct: 210 TINEWEDNERGVSYVFSKVAINKFLSKFNFDLVCRAHMVVEDGYEFFNDRTLVTVFSAPN 269 Query: 451 YCDQMGNKASYI 462 YC + N + + Sbjct: 270 YCGEFDNWGAVM 281 >6FO1-G nrPDB Length = 665 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 51/163 (31%), Positives = 87/163 (53%), Gaps = 9/163 (5%) Query: 5 EGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY 64 EGER + A+ ++A K + N +FK YE AI+ Y++ I + +NA+ Sbjct: 267 EGERKQIE--------AQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALL 318 Query: 65 YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVK 124 NR++AYL+ + Y A D T+AI LD Y K + RR + LGK A +D+ETV+ Sbjct: 319 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 378 Query: 125 VKPNDKDAKMKYQECSK-IVKQKAFERAIAGDEHRRSVVDSLD 166 ++P +K A + + K ++++ ++ R++VV +D Sbjct: 379 LEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPID 421 Score = 79.3 bits (194), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 40/116 (34%), Positives = 67/116 (57%) Query: 31 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 90 LK + N YFK Y+ AI Y++ ++ +P N + NR+ AY R + + A D A+ Sbjct: 136 LKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVA 195 Query: 91 LDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQK 146 L++ Y K Y RR A+ AL K A +DYE V++++PN+ +A + ++ S+ + K Sbjct: 196 LNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASK 251 >4I2W-A nrPDB Length = 961 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 33/111 (29%), Positives = 61/111 (54%), Gaps = 5/111 (4%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPS-----NAIYYGNRSLAYLRTECYG 79 ++ AEE++ + N K +DY A + Y++A++L + Y NR++A L+ + + Sbjct: 5 VQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEDKALRPVLYRNRAMARLKRDDFE 64 Query: 80 YALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDK 130 A D T+A+E D +K +RR+ + LG A +D + +++ PNDK Sbjct: 65 GAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPNDK 115 >2C2L-A nrPDB Length = 281 Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 31/73 (42%), Positives = 43/73 (58%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR 87 A+ELK Q N F + Y A Y +AI NP A+YY NR+L YL+ + AL D R Sbjct: 4 AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRR 63 Query: 88 AIELDKKYIKGYY 100 A+ELD + +K ++ Sbjct: 64 ALELDGQSVKAHF 76 >2GW1-A nrPDB Length = 514 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 1/93 (1%) Query: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDA 85 K A LK + N +F+ K Y++AIK+Y+ A+EL + ++Y N S Y+ + + Sbjct: 4 KYALALKDKGNQFFRNKKYDDAIKYYNWALELK-EDPVFYSNLSACYVSVGDLKKVVEMS 62 Query: 86 TRAIELDKKYIKGYYRRAASNMALGKFRAALRD 118 T+A+EL Y K RRA++N LGKF A+ D Sbjct: 63 TKALELKPDYSKVLLRRASANEGLGKFADAMFD 95 >1QZ2-A nrPDB Length = 336 Score = 53.1 bits (126), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 16/151 (10%) Query: 18 EPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYY 65 E +E L+++ +K + YFK Y+ A+ Y + + E + A+ Sbjct: 137 EMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRL 196 Query: 66 G---NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETV 122 N ++ +L+ + + A+ +A+ELD KG +RR +++A+ F A D++ V Sbjct: 197 ASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKV 256 Query: 123 VKVKPNDKDAKMKYQEC-SKIVKQKAFERAI 152 +++ PN+K AK + C +I +Q A E+ + Sbjct: 257 LQLYPNNKAAKTQLAVCQQRIRRQLAREKKL 287 >5OMP-A nrPDB Length = 462 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 15/136 (11%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYYG---NRS 69 L++A +K + YFK Y A+ Y + + E S + N + Sbjct: 270 LEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLA 329 Query: 70 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPND 129 + YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E V++V P + Sbjct: 330 MCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 389 Query: 130 KDAKMKYQECSKIVKQ 145 K A+++ C K K+ Sbjct: 390 KAARLQISMCQKKAKE 405 >1KT1-A nrPDB Length = 457 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 63/136 (46%), Gaps = 15/136 (11%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYYG---NRS 69 L++A +K + YFK Y A+ Y + + E S + N + Sbjct: 265 LEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLA 324 Query: 70 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPND 129 + YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E V++V P + Sbjct: 325 MCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQN 384 Query: 130 KDAKMKYQECSKIVKQ 145 K A+++ C K K+ Sbjct: 385 KAARLQIFMCQKKAKE 400 >1IHG-A nrPDB Length = 370 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 17/141 (12%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAI----------------ELNPSNAIYYGNRSLA 71 +E+LK N +FK++++E AIK Y++ + +L P N Sbjct: 223 SEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGAC 282 Query: 72 YLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKD 131 L+ + A+ A+E+D K YRRA L ++ AL D + ++ P DK Sbjct: 283 KLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKA 342 Query: 132 AKMKYQEC-SKIVKQKAFERA 151 + + + KI QK E+A Sbjct: 343 IQAELLKVKQKIKAQKDKEKA 363 >5A01-A nrPDB Length = 710 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 45/97 (46%) Query: 47 AIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASN 106 A+ Y +AI + P+ A Y N + AL TRAI+++ + + A+ + Sbjct: 60 ALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIH 119 Query: 107 MALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIV 143 G A++ Y T +K+KP+ DA C +IV Sbjct: 120 KDSGNIPEAIQSYRTALKLKPDFPDAYCNLAHCLQIV 156 >5LVV-A nrPDB Length = 749 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 46/99 (46%) Query: 45 ENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAA 104 + A+ Y +AI ++P+ A Y N + AL TRAI+++ + + A+ Sbjct: 81 QEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLAS 140 Query: 105 SNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIV 143 + G A+ Y T +K+KP+ DA C +IV Sbjct: 141 IHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQIV 179 >1G5B-A nrPDB Length = 221 Score = 42.7 bits (99), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 25/69 (36%), Positives = 38/69 (55%), Gaps = 6/69 (8%) Query: 237 ITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDH 296 I V GD HG + +L+N + G ++ + I GD VDRG+ +VE + +L+ Sbjct: 15 IWVVGDLHGCYTNLMNKLDTIGFDNKKDLLISVGDLVDRGAENVECL------ELITFPW 68 Query: 297 FHLLRGNHE 305 F +RGNHE Sbjct: 69 FRAVRGNHE 77 >1V73-A nrPDB Length = 342 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 23/161 (14%) Query: 221 CKLSTLVETTLKET----EKITVCGDTHGQFYDLLNIFELNGLPSETNPYIF-------N 269 KLS+ ++ + +T +K+ D HGQ+ LL + + + + F Sbjct: 53 TKLSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAFGEGHMVMT 112 Query: 270 GDFVDRGSFSVEVILTLFGFKLLYPD---HFHLLRGNHE-------TDNMNQIYGFEGEV 319 GD DRG EV+ ++ D HLL GNHE ++Q Y + Sbjct: 113 GDIFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRYVHQRYDIATTL 172 Query: 320 KAKYTAQMYELFSEVFEWLPLAQCI--NGKVLIMHGGLFSE 358 + ++Y +E+ +WL I VL MHGG+ SE Sbjct: 173 INRPYNKLYGADTEIGQWLRSKNTIIKINDVLYMHGGISSE 213 >4CGU-A nrPDB Length = 112 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/85 (28%), Positives = 45/85 (52%), Gaps = 9/85 (10%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGD 84 + + E+ K Q N FK Y A+ Y Q I P N + Y N+++A ++ LG+ Sbjct: 2 MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIK-------LGE 54 Query: 85 ATRAIELDKKYIKGYYRRAASNMAL 109 T+AI++ ++ ++ Y A ++A+ Sbjct: 55 YTQAIQMCQQGLR--YTSTAEHVAI 77 >1W3B-A nrPDB Length = 388 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 44/93 (47%) Query: 40 KAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGY 99 +A+ ++ A+ Y +A+ L+P++A+ +GN + Y A+ RAIEL + Y Sbjct: 215 EARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAY 274 Query: 100 YRRAASNMALGKFRAALRDYETVVKVKPNDKDA 132 A + G A Y T +++ P D+ Sbjct: 275 CNLANALKEKGSVAEAEDCYNTALRLCPTHADS 307 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 30/124 (24%), Positives = 50/124 (40%), Gaps = 6/124 (4%) Query: 5 EGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY 64 E C + R EP G L + +F+ + + + F + AI+ NP A Sbjct: 16 EAAERHCMQLWRQEPDNTGVLLLLSSI------HFQCRRLDRSAHFSTLAIKQNPLLAEA 69 Query: 65 YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVK 124 Y N Y A+ A+ L +I GY AA+ +A G A++ Y + ++ Sbjct: 70 YSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQ 129 Query: 125 VKPN 128 P+ Sbjct: 130 YNPD 133 Score = 31.6 bits (70), Expect = 0.90, Method: Compositional matrix adjust. Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 22/124 (17%) Query: 41 AKDYENAIKFYSQAIELNPSNAIY-----YGNRSLAYLRTE----CYGYALGDATRAIEL 91 A D E A++ Y A++ NP +Y GN A R E CY +AIE Sbjct: 114 AGDMEGAVQAYVSALQYNPD--LYCVRSDLGNLLKALGRLEEAKACY-------LKAIET 164 Query: 92 DKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQ-KAFER 150 + + A G+ A+ +E V + PN DA Y ++K+ + F+R Sbjct: 165 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YINLGNVLKEARIFDR 221 Query: 151 AIAG 154 A+A Sbjct: 222 AVAA 225 >5JHE-A nrPDB Length = 397 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 24/145 (16%) Query: 24 TLKRAEELKTQANDYFKAKDYENAIKFYSQAIE-------------------LNPSNAIY 64 L+ A +K FK KDY NA Y +++ +N IY Sbjct: 240 ALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIY 299 Query: 65 YGNRSLAYLRTECYGYALGDATRAIELD----KKYIKGYYRRAASNMALGKFRAALRDYE 120 N SL E Y A+ AT +E+D + K YYRR S + + AL+DY Sbjct: 300 L-NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 358 Query: 121 TVVKVKPNDKDAKMKYQECSKIVKQ 145 + P+D+ + + + ++++++ Sbjct: 359 FCKEKNPDDEVIEQRIEYVNRLIEE 383 >5VJW-A nrPDB Length = 309 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 11/84 (13%) Query: 231 LKETEKITVC-GDTHGQFYDLLNIFELNGLPSETNP-------YIFNGDFVDRGSFSVEV 282 + + + +C GD HG L N++ LN L S +P IF GD+ DRG + +V Sbjct: 1 MAQKPRTVICVGDIHGYISKLNNLW-LN-LQSAIDPSDFSSALVIFLGDYCDRGPETRKV 58 Query: 283 ILTLFGFKLLYPDHFHL-LRGNHE 305 I L +PD H+ L GNH+ Sbjct: 59 IDFLISLPEKHPDQTHVFLAGNHD 82 >2W42-A nrPDB Length = 427 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 32/127 (25%), Positives = 54/127 (42%), Gaps = 29/127 (22%) Query: 130 KDAKMKYQECSKIVK--------QKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKL 181 KD M + E S IV + ++ + G ++S D D+E +T+ PK+ Sbjct: 204 KDGTMLWNEISPIVTSSEYLTYLKSTIKKVVYG--FKKSNPD-WDVEKLTLHVSGKRPKM 260 Query: 182 EDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 +DG+ I +K+ ++ K Q+ + R Y IL L ET V G Sbjct: 261 KDGETKI--LKETVEELKKQEMVSRDVKYAIL----------------HLNETHPFWVMG 302 Query: 242 DTHGQFY 248 D + +F+ Sbjct: 303 DPNNRFH 309 >2IF4-A nrPDB Length = 338 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 17/132 (12%) Query: 16 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY--YG------- 66 R + E + A+ K N FK + E A++ Y AI + ++ YG Sbjct: 167 RSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMAL 226 Query: 67 --------NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRD 118 N + ++ + Y A+G + ++K K +RR + LG+ +A D Sbjct: 227 AVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDD 286 Query: 119 YETVVKVKPNDK 130 + K P+DK Sbjct: 287 FRKAQKYAPDDK 298 >5G04-F nrPDB Length = 824 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 20/92 (21%), Positives = 47/92 (51%) Query: 38 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97 Y+K + + A + +A+++NP +++ + + + AL +AI +D K Sbjct: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 Query: 98 GYYRRAASNMALGKFRAALRDYETVVKVKPND 129 + RA+ A K+++AL++ E + ++ P + Sbjct: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKE 736 >2Y4T-A nrPDB Length = 450 Score = 32.0 bits (71), Expect = 0.61, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 26/46 (56%) Query: 81 ALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVK 126 AL A++ D YYRRA +A+GK +AAL D V+++K Sbjct: 45 ALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLK 90 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 6/86 (6%) Query: 47 AIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDK--KYIKGYYRRAA 104 AI+ S+ +++ P N +R+ AYL E Y A+ D A E ++ + I+ +A Sbjct: 314 AIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQ 373 Query: 105 SNMALGKFRAALRDYETVVKVKPNDK 130 + ++ RDY ++ VK N K Sbjct: 374 RLLK----QSQKRDYYKILGVKRNAK 395 >4OFZ-A nrPDB Length = 514 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 26/110 (23%), Positives = 45/110 (40%), Gaps = 4/110 (3%) Query: 48 IKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYY--RRAAS 105 ++ +A E N + R + L T+ +GD TR +E D KY+ RR Sbjct: 119 VEILKRAYEKLTDNQTHSFQREMCTLTTK-LSVNIGDETRGLEKDLKYLDALMNIRREEP 177 Query: 106 NMALGKFRAALRDYETVVKVKPNDKDAKMK-YQECSKIVKQKAFERAIAG 154 N+ + + + + P K+ +K Y++ K +K AI G Sbjct: 178 NLLWPIIMSRVDLFSILANYHPKGKETFLKEYEDTVKFLKTFISSEAITG 227 >4Z54-A nrPDB Length = 287 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 2/62 (3%) Query: 402 VSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGG--RCVTVFSAPNYCDQMGNKA 459 V+ F V++ N+ + I ++ E+KA G+ + GG +TV P + DQ+ N+ Sbjct: 36 VNTLFKSQVSRKASSWNREEKIPKTVEIKAIGHVIEEGGVKMKLTVIDTPGFGDQINNEN 95 Query: 460 SY 461 + Sbjct: 96 CW 97 >6B85-J nrPDB Length = 223 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 10/95 (10%) Query: 40 KAKDYENAIKFYSQAIELNPSNAIYYGN-----RSLAYLRTECYGYALGDATRAIELDKK 94 K K + A + Y +AIEL P++A + L L Y +AIELD + Sbjct: 127 KLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAY-----KKAIELDPE 181 Query: 95 YIKGYYRRAASNMALGKFRAALRDYETVVKVKPND 129 + + LG+ A Y+ +++ PND Sbjct: 182 DAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 Score = 28.1 bits (61), Expect = 9.8, Method: Compositional matrix adjust. Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 11/117 (9%) Query: 47 AIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASN 106 A + Y +AIEL+P++A+ + + + A +AIEL + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 107 MALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQ--------KAFERAIAGD 155 LG+ A Y+ +++ P D +A ++E K++++ +A+++AI D Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEA---WKELGKVLEKLGRLDEAAEAYKKAIELD 213 >3D3U-A nrPDB Length = 439 Score = 29.6 bits (65), Expect = 3.2, Method: Compositional matrix adjust. Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 440 GRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKP 486 G CVT + N D + + L+G+ LR + TA+ HP+ +P Sbjct: 376 GACVT--TGRNEVDYVVTEYGVARLRGATLRQRAEALTAIAHPDFRP 420 >2J5A-A nrPDB Length = 110 Score = 28.5 bits (62), Expect = 7.6, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 2/35 (5%) Query: 115 ALRDYETVVKVKP--NDKDAKMKYQECSKIVKQKA 147 LR YETV VKP ++++ K K+++ + +KQK Sbjct: 6 TLRYYETVFAVKPTLSEEEMKKKFEQVKEFIKQKG 40 >3KHX-A nrPDB Length = 492 Score = 28.1 bits (61), Expect = 9.3, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 18/72 (25%) Query: 263 TNPYIFNGDFVDR----------GSFSVEV-ILT-------LFGFKLLYPDHFHLLRGNH 304 +N Y+FN DF ++ G + + ++T LFG L YP+ F + Sbjct: 326 SNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGVITYDNENAGLFGINLRYPEGFEFEKAMD 385 Query: 305 ETDNMNQIYGFE 316 N Q YGFE Sbjct: 386 RFANEIQQYGFE 397 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4JA9-A nrPDB 760 0.0 5JJT-A nrPDB 687 0.0 4ZVZ-A nrPDB 553 e-158 3ICF-A nrPDB 419 e-117 4ORB-A nrPDB 416 e-116 4ORC-A nrPDB 413 e-115 4IL1-A nrPDB 410 e-115 5W0W-C nrPDB 405 e-113 1S70-A nrPDB 392 e-109 3V4Y-A nrPDB 392 e-109 5JPE-A nrPDB 366 e-101 1A17-A nrPDB 233 1e-61 6FO1-G nrPDB 181 5e-46 1V73-A nrPDB 159 3e-39 1QZ2-A nrPDB 147 1e-35 5OMP-A nrPDB 141 8e-34 1KT1-A nrPDB 139 3e-33 1IHG-A nrPDB 136 2e-32 5LVV-A nrPDB 134 8e-32 5A01-A nrPDB 134 1e-31 4I2W-A nrPDB 128 7e-30 2GW1-A nrPDB 114 7e-26 2C2L-A nrPDB 111 6e-25 1G5B-A nrPDB 90 3e-18 4CGU-A nrPDB 89 6e-18 Sequences not found previously or not previously below threshold: 2IF4-A nrPDB 84 1e-16 1W3B-A nrPDB 84 2e-16 5MGX-E nrPDB 74 1e-13 6B85-J nrPDB 71 1e-12 2DFJ-A nrPDB 69 5e-12 2Y4T-A nrPDB 65 7e-11 5G04-F nrPDB 63 3e-10 5JHE-A nrPDB 63 4e-10 5G05-C nrPDB 62 5e-10 5FZQ-A nrPDB 60 2e-09 5KHR-J nrPDB 50 2e-06 5VJW-A nrPDB 49 5e-06 6C95-A nrPDB 46 5e-05 5WQL-B nrPDB 45 1e-04 5OJF-A nrPDB 44 1e-04 5OJ8-A nrPDB 44 2e-04 3ZFW-A nrPDB 44 2e-04 3NF1-A nrPDB 44 2e-04 6FUZ-A nrPDB 44 2e-04 5NNP-A nrPDB 43 3e-04 5G04-X nrPDB 42 6e-04 5ZYQ-A nrPDB 42 7e-04 2QJC-A nrPDB 41 0.001 5AEM-A nrPDB 40 0.003 4UZY-A nrPDB 40 0.003 5ZYP-A nrPDB 39 0.004 4JHR-A nrPDB 39 0.006 5LJ5-S nrPDB 38 0.009 5EFR-A nrPDB 38 0.009 4HOQ-A nrPDB 38 0.011 4KVO-A nrPDB 37 0.014 5CQS-A nrPDB 37 0.018 4YG8-B nrPDB 37 0.028 4YMR-A nrPDB 35 0.081 4ABN-A nrPDB 35 0.098 5UDI-A nrPDB 35 0.11 2W42-A nrPDB 34 0.14 4I1A-A nrPDB 34 0.24 5JZ6-A nrPDB 33 0.27 4HOU-A nrPDB 33 0.27 4G1T-A nrPDB 33 0.29 6N3Q-F nrPDB 33 0.38 5XJC-J nrPDB 33 0.41 1HH8-A nrPDB 32 0.73 5O09-1C nrPDB 32 0.87 4WRT-C nrPDB 32 0.87 5CCB-B nrPDB 31 1.2 6MFV-A nrPDB 30 2.0 2ZAO-A nrPDB 30 3.1 3R25-A nrPDB 30 3.2 3R6N-A nrPDB 29 3.8 6CQO-A nrPDB 29 6.4 3JCM-G nrPDB 29 7.7 5A1Y-X nrPDB 28 8.5 5DSE-A nrPDB 28 9.0 >4JA9-A nrPDB Length = 488 Score = 760 bits (1963), Expect = 0.0, Method: Composition-based stats. Identities = 484/484 (100%), Positives = 484/484 (100%) Query: 16 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 75 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT Sbjct: 5 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 64 Query: 76 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 135 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK Sbjct: 65 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 124 Query: 136 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLM 195 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLM Sbjct: 125 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLM 184 Query: 196 QWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFE 255 QWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFE Sbjct: 185 QWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFE 244 Query: 256 LNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF 315 LNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF Sbjct: 245 LNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGF 304 Query: 316 EGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQP 375 EGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQP Sbjct: 305 EGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQP 364 Query: 376 PDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYE 435 PDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYE Sbjct: 365 PDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYE 424 Query: 436 VAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQ 495 VAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQ Sbjct: 425 VAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQ 484 Query: 496 LGMM 499 LGMM Sbjct: 485 LGMM 488 >5JJT-A nrPDB Length = 479 Score = 687 bits (1772), Expect = 0.0, Method: Composition-based stats. Identities = 268/478 (56%), Positives = 359/478 (75%), Gaps = 1/478 (0%) Query: 20 PAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYG 79 + RAEE K+QAN+ FK Y +AI Y++AIELN +NA+Y+ NR+ A+ + E YG Sbjct: 1 NENSDVSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYG 60 Query: 80 YALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQEC 139 A+ DA++AIE+D +Y KGYYRR A+ +A+GKF+ AL+D++ V ++ PND DA K +EC Sbjct: 61 SAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLKEC 120 Query: 140 SKIVKQKAFERAIAGD-EHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLMQWY 198 K V + FE AI+ RRSV +S+D ++ +E +YSG ++E +VT+ F+K +M+ + Sbjct: 121 EKAVMKLKFEEAISVPVSERRSVAESIDFHTIEVEPQYSGARIEGEEVTLDFVKTMMEDF 180 Query: 199 KDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNG 258 K+QK LH++ AYQI++Q +++L L +LV+ ++ + ITVCGD HGQFYDLLNIFELNG Sbjct: 181 KNQKTLHKRYAYQIVLQTRQILLALPSLVDISVPHGKHITVCGDVHGQFYDLLNIFELNG 240 Query: 259 LPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGE 318 LPSE NPY+FNGDFVDRGSFSVE+ILTLF FK + P +L RGNHE+ +MN+IYGFEGE Sbjct: 241 LPSEENPYLFNGDFVDRGSFSVEIILTLFAFKCMCPSSIYLARGNHESKSMNKIYGFEGE 300 Query: 319 VKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDS 378 V++K + + +LF+EVF +LPLA INGKV ++HGGLFS DGV L DIR I+R +PP+ Sbjct: 301 VRSKLSEKFVDLFAEVFCYLPLAHVINGKVFVVHGGLFSVDGVKLSDIRAIDRFCEPPEE 360 Query: 379 GPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAH 438 G MC+LLWSDPQP GR SKRGV FG DVTK FL++N LD ++RSHEVK EGYEV H Sbjct: 361 GLMCELLWSDPQPLPGRGPSKRGVGLSFGGDVTKRFLQDNNLDLLVRSHEVKDEGYEVEH 420 Query: 439 GGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPHPNVKPMAYANTLLQL 496 G+ +TVFSAPNYCDQMGNK ++I + D++P F+AVPHP+VKPMAYAN L++ Sbjct: 421 DGKLITVFSAPNYCDQMGNKGAFIRFEAPDMKPNIVTFSAVPHPDVKPMAYANNFLRM 478 >4ZVZ-A nrPDB Length = 333 Score = 553 bits (1424), Expect = e-158, Method: Composition-based stats. Identities = 326/331 (98%), Positives = 329/331 (99%) Query: 169 SMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVE 228 SMTIEDEYSGPKLEDGKVTI+FMK+LMQWYKDQKKLHRKCAYQILVQVKEVL KLSTLVE Sbjct: 3 SMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVE 62 Query: 229 TTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFG 288 TTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFG Sbjct: 63 TTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFG 122 Query: 289 FKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKV 348 FKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKV Sbjct: 123 FKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKV 182 Query: 349 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGP 408 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS+SKRGVSCQFGP Sbjct: 183 LIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGP 242 Query: 409 DVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD 468 DVTKAFLEEN LDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD Sbjct: 243 DVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSD 302 Query: 469 LRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 499 LRPQFHQFTAVPHPNVKPMAYANTLLQLGMM Sbjct: 303 LRPQFHQFTAVPHPNVKPMAYANTLLQLGMM 333 >3ICF-A nrPDB Length = 335 Score = 419 bits (1078), Expect = e-117, Method: Composition-based stats. Identities = 143/332 (43%), Positives = 201/332 (60%), Gaps = 15/332 (4%) Query: 173 EDEYSGPKLEDGKVTITFMKDLMQW-YKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTL 231 ++ + G K+++ ++ F+ ++ + K L +K I+ + + ++VE Sbjct: 1 KNAFKGAKIKN--MSQEFISKMVNDLFLKGKYLPKKYVAAIISHADTLFRQEPSMVELEN 58 Query: 232 KETE--KITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGF 289 T KI+VCGDTHGQFYD+LN+F G + Y+FNGDFVDRGS+S EV L + Sbjct: 59 NSTPDVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEVALLFYCL 118 Query: 290 KLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVL 349 K+L+P++F L RGNHE+DNMN+IYGFE E K KY+ +++ +F++ FE LPLA IN L Sbjct: 119 KILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFAQSFESLPLATLINNDYL 178 Query: 350 IMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPD 409 +MHGGL S+ TL D + I+R QPP G +LLW+DPQ NG S+RG+ FGPD Sbjct: 179 VMHGGLPSDPSATLSDFKNIDRFAQPPRDGAFMELLWADPQEANGMGPSQRGLGHAFGPD 238 Query: 410 VTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHL----- 464 +T FL N+L I RSHE++ G + G+ +TVFSAPNYCD GN IH+ Sbjct: 239 ITDRFLRNNKLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVIHVVPGHG 298 Query: 465 -----QGSDLRPQFHQFTAVPHPNVKPMAYAN 491 + D F AV HP++KPMAY+N Sbjct: 299 ILQAGRNDDQNLIIETFEAVEHPDIKPMAYSN 330 >4ORB-A nrPDB Length = 519 Score = 416 bits (1070), Expect = e-116, Method: Composition-based stats. Identities = 120/319 (37%), Positives = 180/319 (56%), Gaps = 27/319 (8%) Query: 183 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 38 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 89 Query: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 90 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 148 Query: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL S + Sbjct: 149 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEIN 207 Query: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 413 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 208 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCD 267 Query: 414 FLEENQLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGS 467 FL+ N L I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 268 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 327 Query: 468 DLRPQFHQFTAVPHPNVKP 486 + QF PHP P Sbjct: 328 VM--NIRQFNCSPHPYWLP 344 >4ORC-A nrPDB Length = 544 Score = 413 bits (1061), Expect = e-115, Method: Composition-based stats. Identities = 123/319 (38%), Positives = 181/319 (56%), Gaps = 27/319 (8%) Query: 183 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 DG + +K L++ + ++ + A +I+ + +L + T++E ITVCG Sbjct: 67 DGIPRVDVLKNHLVK----EGRVDEEIALRIINEGAAILRREKTMIEVE----APITVCG 118 Query: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 119 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLR 177 Query: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361 GNHE ++ + + F+ E K KY+ ++YE E F+ LPLA +N + L +HGGL S + Sbjct: 178 GNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGL-SPEIH 236 Query: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 413 TLDDIR+++R ++PP GPMCDLLWSDP G S+ RG S + Sbjct: 237 TLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCE 296 Query: 414 FLEENQLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGS 467 FL+ N L IIR+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 297 FLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 356 Query: 468 DLRPQFHQFTAVPHPNVKP 486 + QF PHP P Sbjct: 357 VM--NIRQFNCSPHPYWLP 373 >4IL1-A nrPDB Length = 823 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 120/319 (37%), Positives = 180/319 (56%), Gaps = 27/319 (8%) Query: 183 DGKVTITFMK-DLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 DGK + +K LM+ + +L A +I+ + +L + L++ +TVCG Sbjct: 371 DGKPRVDILKAHLMK----EGRLEESVALRIITEGASILRQEKNLLDID----APVTVCG 422 Query: 242 DTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLR 301 D HGQF+DL+ +FE+ G P+ T Y+F GD+VDRG FS+E +L L+ K+LYP LLR Sbjct: 423 DIHGQFFDLMKLFEVGGSPANTR-YLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLR 481 Query: 302 GNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGV 361 GNHE ++ + + F+ E K KY+ ++Y+ + F+ LPLA +N + L +HGGL S + Sbjct: 482 GNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGL-SPEIN 540 Query: 362 TLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSK--------RGVSCQFGPDVTKA 413 TLDDIRK++R ++PP GPMCD+LWSDP G ++ RG S + Sbjct: 541 TLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCD 600 Query: 414 FLEENQLDYIIRSHEVKAEGYEVAHGGR------CVTVFSAPNYCDQMGNKASYIHLQGS 467 FL+ N L I+R+HE + GY + + +T+FSAPNY D NKA+ + + + Sbjct: 601 FLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENN 660 Query: 468 DLRPQFHQFTAVPHPNVKP 486 + QF PHP P Sbjct: 661 VM--NIRQFNCSPHPYWLP 677 >5W0W-C nrPDB Length = 311 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 122/302 (40%), Positives = 179/302 (59%), Gaps = 14/302 (4%) Query: 183 DGKVTITFMKDLMQWYK---DQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITV 239 D KV F K+L QW + + K+L + + KE+L K S + E +TV Sbjct: 4 DEKV---FTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCP----VTV 56 Query: 240 CGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHL 299 CGD HGQF+DL+ +F + G +TN Y+F GD+VDRG +SVE + L K+ Y + + Sbjct: 57 CGDVHGQFHDLMELFRIGGKSPDTN-YLFMGDYVDRGYYSVETVTLLVALKVRYRERITI 115 Query: 300 LRGNHETDNMNQIYGFEGEVKAKY-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSE 358 LRGNHE+ + Q+YGF E KY A +++ F+++F++LPL ++G++ +HGGL S Sbjct: 116 LRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGL-SP 174 Query: 359 DGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVSCQFGPDVTKAFLEEN 418 TLD IR ++R ++ P GPMCDLLWSDP + G +S RG FG D+++ F N Sbjct: 175 SIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHAN 234 Query: 419 QLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTA 478 L + R+H++ EGY H VT+FSAPNYC + GN+A+ + L + L+ F QF Sbjct: 235 GLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDT-LKYSFLQFDP 293 Query: 479 VP 480 P Sbjct: 294 AP 295 >1S70-A nrPDB Length = 330 Score = 392 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 107/295 (36%), Positives = 167/295 (56%), Gaps = 12/295 (4%) Query: 181 LEDGKVTITFMKDLMQWYKDQK-----KLHRKCAYQILVQVKEVLCKLSTLVETTLKETE 235 + DG++ + + + + + ++ + ++ +E+ L+E Sbjct: 4 MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELE----A 59 Query: 236 KITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPD 295 + +CGD HGQ+ DLL +FE G P E N Y+F GD+VDRG S+E I L +K+ YP+ Sbjct: 60 PLKICGDIHGQYTDLLRLFEYGGFPPEAN-YLFLGDYVDRGKQSLETICLLLAYKIKYPE 118 Query: 296 HFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGL 355 +F LLRGNHE ++N+IYGF E K ++ ++++ F++ F LP+A ++ K+ HGGL Sbjct: 119 NFFLLRGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL 178 Query: 356 FSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQ-NGRSVSKRGVSCQFGPDVTKAF 414 S D +++ IR+I R PD+G +CDLLWSDP G + RGVS FG DV F Sbjct: 179 -SPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKF 237 Query: 415 LEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDL 469 L + LD I R+H+V +GYE + VT+FSAPNYC + N + + + + Sbjct: 238 LNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLM 292 >3V4Y-A nrPDB Length = 306 Score = 392 bits (1007), Expect = e-109, Method: Composition-based stats. Identities = 107/268 (39%), Positives = 160/268 (59%), Gaps = 7/268 (2%) Query: 203 KLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSE 262 +L + ++ +E+ L+E + +CGD HGQ+YDLL +FE G P E Sbjct: 28 QLTENEIRGLCLKSREIFLSQPILLELE----APLKICGDIHGQYYDLLRLFEYGGFPPE 83 Query: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322 +N Y+F GD+VDRG S+E I L +K+ YP++F LLRGNHE ++N+IYGF E K + Sbjct: 84 SN-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRR 142 Query: 323 YTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMC 382 Y ++++ F++ F LP+A ++ K+ HGGL S D +++ IR+I R PD G +C Sbjct: 143 YNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGL-SPDLQSMEQIRRIMRPTDVPDQGLLC 201 Query: 383 DLLWSDPQPQ-NGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGR 441 DLLWSDP G + RGVS FG +V FL ++ LD I R+H+V +GYE + Sbjct: 202 DLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQ 261 Query: 442 CVTVFSAPNYCDQMGNKASYIHLQGSDL 469 VT+FSAPNYC + N + + + + + Sbjct: 262 LVTLFSAPNYCGEFDNAGAMMSVDETLM 289 >5JPE-A nrPDB Length = 311 Score = 366 bits (940), Expect = e-101, Method: Composition-based stats. Identities = 104/268 (38%), Positives = 148/268 (55%), Gaps = 8/268 (2%) Query: 212 ILVQVKEVLCKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGD 271 I +E+ +L+E + V GD HGQ++DL+ IF G P +TN Y+F GD Sbjct: 36 ICASAREIFLSQPSLLELA----PPVKVVGDVHGQYHDLIRIFSKCGFPPKTN-YLFLGD 90 Query: 272 FVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELF 331 +V+RG S+E IL L +K+ YP++F LLRGNHE N+ ++YGF E K + + ++LF Sbjct: 91 YVNRGKQSLETILLLLCYKIKYPENFFLLRGNHECANVTRVYGFYDECKRRCNIKTWKLF 150 Query: 332 SEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQP 391 + F LP+A + GK+ +HGGL S ++D+IR I R PD G + DLLWSDP Sbjct: 151 IDTFNTLPIAAIVAGKIFCVHGGL-SPVLNSMDEIRNIARPTDVPDFGLLNDLLWSDPAD 209 Query: 392 Q-NGRSVSKRGVSCQFGPDVTKAFLEENQLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPN 450 N ++RGVS F FL + D + R+H V +GYE + VTVFSAPN Sbjct: 210 TINEWEDNERGVSYVFSKVAINKFLSKFNFDLVCRAHMVVEDGYEFFNDRTLVTVFSAPN 269 Query: 451 YCDQMGNKASYIHLQGSDLRPQFHQFTA 478 YC + N + + + DL F Sbjct: 270 YCGEFDNWGAVMGV-SEDLLCSFELLDP 296 >1A17-A nrPDB Length = 166 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 161/166 (96%), Positives = 165/166 (99%) Query: 16 RDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 75 RDEPPA+G LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT Sbjct: 1 RDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRT 60 Query: 76 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 135 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP+DKDAKMK Sbjct: 61 ECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMK 120 Query: 136 YQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKL 181 YQEC+KIVKQKAFERAIAGDEH+RSVVDSLDIESMTIEDEYSGPKL Sbjct: 121 YQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKL 166 >6FO1-G nrPDB Length = 665 Score = 181 bits (460), Expect = 5e-46, Method: Composition-based stats. Identities = 51/163 (31%), Positives = 87/163 (53%), Gaps = 9/163 (5%) Query: 5 EGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY 64 EGER + A+ ++A K + N +FK YE AI+ Y++ I + +NA+ Sbjct: 267 EGERKQIE--------AQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALL 318 Query: 65 YGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVK 124 NR++AYL+ + Y A D T+AI LD Y K + RR + LGK A +D+ETV+ Sbjct: 319 PANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLL 378 Query: 125 VKPNDKDAKMKYQECSK-IVKQKAFERAIAGDEHRRSVVDSLD 166 ++P +K A + + K ++++ ++ R++VV +D Sbjct: 379 LEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPID 421 Score = 123 bits (309), Expect = 2e-28, Method: Composition-based stats. Identities = 46/150 (30%), Positives = 80/150 (53%), Gaps = 4/150 (2%) Query: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDA 85 ++A LK + N YFK Y+ AI Y++ ++ +P N + NR+ AY R + + A D Sbjct: 131 QKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDC 190 Query: 86 TRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQ 145 A+ L++ Y K Y RR A+ AL K A +DYE V++++PN+ +A + ++ S+ + Sbjct: 191 NLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALAS 250 Query: 146 KAFERAIAGDEHRRSVVDSLDIESMTIEDE 175 K + + V+ S + E IE + Sbjct: 251 KEN----SYPKEADIVIKSTEGERKQIEAQ 276 >1V73-A nrPDB Length = 342 Score = 159 bits (402), Expect = 3e-39, Method: Composition-based stats. Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 31/249 (12%) Query: 221 CKLSTLVETTLKET----EKITVCGDTHGQFYDLLNIFELNGLPSETNPYIF-------N 269 KLS+ ++ + +T +K+ D HGQ+ LL + + + + F Sbjct: 53 TKLSSEIKQIMPDTYLGIKKVVALSDVHGQYDVLLTLLKKQKIIDSDGNWAFGEGHMVMT 112 Query: 270 GDFVDRGSFSVEVILTLFGFKLLYPD---HFHLLRGNHE-------TDNMNQIYGFEGEV 319 GD DRG EV+ ++ D HLL GNHE ++Q Y + Sbjct: 113 GDIFDRGHQVNEVLWFMYQLDQQARDAGGMVHLLMGNHEQMVLGGDLRYVHQRYDIATTL 172 Query: 320 KAKYTAQMYELFSEVFEWLPLAQCI--NGKVLIMHGGLFSEDGV---TLDDIRKIER-NR 373 + ++Y +E+ +WL I VL MHGG+ SE TLD + R N Sbjct: 173 INRPYNKLYGADTEIGQWLRSKNTIIKINDVLYMHGGISSEWISRELTLDKANALYRANV 232 Query: 374 QPPDSGPMCDLLWSDPQPQNGRSVS-KRG-VSCQFGPDVTKAFLEENQLDYIIRSHEVKA 431 D L + G + RG S F L+ +++I+ H + Sbjct: 233 DASKKSLKADDLLN--FLFFGNGPTWYRGYFSETFTEAELDTILQHFNVNHIVVGHTSQE 290 Query: 432 EGYEVAHGG 440 + H Sbjct: 291 RVLGLFHNK 299 >1QZ2-A nrPDB Length = 336 Score = 147 bits (370), Expect = 1e-35, Method: Composition-based stats. Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 16/151 (10%) Query: 18 EPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYY 65 E +E L+++ +K + YFK Y+ A+ Y + + E + A+ Sbjct: 137 EMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRL 196 Query: 66 G---NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETV 122 N ++ +L+ + + A+ +A+ELD KG +RR +++A+ F A D++ V Sbjct: 197 ASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKV 256 Query: 123 VKVKPNDKDAKMKYQECSK-IVKQKAFERAI 152 +++ PN+K AK + C + I +Q A E+ + Sbjct: 257 LQLYPNNKAAKTQLAVCQQRIRRQLAREKKL 287 >5OMP-A nrPDB Length = 462 Score = 141 bits (355), Expect = 8e-34, Method: Composition-based stats. Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 15/143 (10%) Query: 18 EPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYY 65 E + L++A +K + YFK Y A+ Y + + E S + Sbjct: 263 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLL 322 Query: 66 G---NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETV 122 N ++ YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E V Sbjct: 323 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKV 382 Query: 123 VKVKPNDKDAKMKYQECSKIVKQ 145 ++V P +K A+++ C K K+ Sbjct: 383 LEVNPQNKAARLQISMCQKKAKE 405 >1KT1-A nrPDB Length = 457 Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats. Identities = 37/143 (25%), Positives = 65/143 (45%), Gaps = 15/143 (10%) Query: 18 EPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAI------------ELNPSNAIYY 65 E + L++A +K + YFK Y A+ Y + + E S + Sbjct: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKESKASESFLL 317 Query: 66 G---NRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETV 122 N ++ YL+ Y A+ +A+ LD KG YRR + + + +F +A D+E V Sbjct: 318 AAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKV 377 Query: 123 VKVKPNDKDAKMKYQECSKIVKQ 145 ++V P +K A+++ C K K+ Sbjct: 378 LEVNPQNKAARLQIFMCQKKAKE 400 >1IHG-A nrPDB Length = 370 Score = 136 bits (342), Expect = 2e-32, Method: Composition-based stats. Identities = 39/157 (24%), Positives = 65/157 (41%), Gaps = 17/157 (10%) Query: 12 AEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIE--------------- 56 + D + L +E+LK N +FK++++E AIK Y++ + Sbjct: 207 EDADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGA 266 Query: 57 -LNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAA 115 L P N L+ + A+ A+E+D K YRRA L ++ A Sbjct: 267 KLQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQA 326 Query: 116 LRDYETVVKVKPNDKDAKMKYQEC-SKIVKQKAFERA 151 L D + ++ P DK + + + KI QK E+A Sbjct: 327 LADLKKAQEIAPEDKAIQAELLKVKQKIKAQKDKEKA 363 >5LVV-A nrPDB Length = 749 Score = 134 bits (337), Expect = 8e-32, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 1/144 (0%) Query: 1 MAMAEGERTECAEPPRDEPPAEGTL-KRAEELKTQANDYFKAKDYENAIKFYSQAIELNP 59 +A + E+ E R A + A A+ + + A+ Y +AI ++P Sbjct: 36 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 95 Query: 60 SNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDY 119 + A Y N + AL TRAI+++ + + A+ + G A+ Y Sbjct: 96 TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASY 155 Query: 120 ETVVKVKPNDKDAKMKYQECSKIV 143 T +K+KP+ DA C +IV Sbjct: 156 RTALKLKPDFPDAYCNLAHCLQIV 179 Score = 37.4 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 18/61 (29%), Gaps = 2/61 (3%) Query: 93 KKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAI 152 + A G A+R Y ++V P A + +Q + A+ Sbjct: 27 GTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ--QQGKLQEAL 84 Query: 153 A 153 Sbjct: 85 M 85 Score = 36.6 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 17/59 (28%), Gaps = 7/59 (11%) Query: 21 AEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYG 79 A+ A K N AI Y A++L P Y N + + Sbjct: 132 ADAHSNLASIHKDSGNI-------PEAIASYRTALKLKPDFPDAYCNLAHCLQIVCDWT 183 >5A01-A nrPDB Length = 710 Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 1/144 (0%) Query: 1 MAMAEGERTECAEPPRDEPPAEGTL-KRAEELKTQANDYFKAKDYENAIKFYSQAIELNP 59 +A + E+ E R A A A+ + + A+ Y +AI + P Sbjct: 13 LANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQP 72 Query: 60 SNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDY 119 + A Y N + AL TRAI+++ + + A+ + G A++ Y Sbjct: 73 TFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSY 132 Query: 120 ETVVKVKPNDKDAKMKYQECSKIV 143 T +K+KP+ DA C +IV Sbjct: 133 RTALKLKPDFPDAYCNLAHCLQIV 156 Score = 36.6 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 12/59 (20%), Positives = 18/59 (30%), Gaps = 7/59 (11%) Query: 21 AEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYG 79 A+ A K N AI+ Y A++L P Y N + + Sbjct: 109 ADAHSNLASIHKDSGNI-------PEAIQSYRTALKLKPDFPDAYCNLAHCLQIVCDWT 160 >4I2W-A nrPDB Length = 961 Score = 128 bits (321), Expect = 7e-30, Method: Composition-based stats. Identities = 47/215 (21%), Positives = 92/215 (42%), Gaps = 38/215 (17%) Query: 24 TLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSN-----AIYYGNRSLAYLRTECY 78 ++ AEE++ + N K +DY A + Y++A++L + Y NR++A L+ + + Sbjct: 4 RVQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEDKALRPVLYRNRAMARLKRDDF 63 Query: 79 GYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQE 138 A D T+A+E D +K +RR+ + LG A +D + +++ PNDK Q Sbjct: 64 EGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDAKEALRLSPNDKGIVEVLQR 123 Query: 139 CSKI-----------------VKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGP-- 179 K +++ AF E + + +++L + E +G Sbjct: 124 LVKANNDKIKQTTSLANKVTDMEKLAFRGEAKDTEQKMTALNNLLVLCRESESGATGVWN 183 Query: 180 --------------KLEDGKVTITFMKDLMQWYKD 200 E+ +VT+T ++ L + K+ Sbjct: 184 QGALVPFVLNLINDASENEEVTVTAIRILDETIKN 218 >2GW1-A nrPDB Length = 514 Score = 114 bits (286), Expect = 7e-26, Method: Composition-based stats. Identities = 38/113 (33%), Positives = 63/113 (55%), Gaps = 2/113 (1%) Query: 23 GTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYAL 82 K A LK + N +F+ K Y++AIK+Y+ A+EL + ++Y N S Y+ + Sbjct: 1 EKDKYALALKDKGNQFFRNKKYDDAIKYYNWALELK-EDPVFYSNLSACYVSVGDLKKVV 59 Query: 83 GDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMK 135 +T+A+EL Y K RRA++N LGKF A+ D +V+ + + DA ++ Sbjct: 60 EMSTKALELKPDYSKVLLRRASANEGLGKFADAMFDL-SVLSLNGDFNDASIE 111 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 39/217 (17%), Positives = 72/217 (33%), Gaps = 11/217 (5%) Query: 13 EPPRDEPPAEGTLKRAEELKTQANDYFK--AKDYENAIKFYSQAIELNPSNAIYYGNRSL 70 E D+ + LK + + FK D A + +AIEL P Y +L Sbjct: 220 EEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPLGAHEDIKKAIELFP-RVNSYIYMAL 278 Query: 71 AYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDK 130 +A++LD YY R N L + A +D++ ++ P + Sbjct: 279 IMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENI 338 Query: 131 DAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITF 190 ++ C + K + E +R ++ ++ + L D Sbjct: 339 FPYIQLA-CLAYRENKFDDCETLFSEAKRKFPEAPEV------PNFFAEILTDKNDFDKA 391 Query: 191 MKDLMQWYKDQKKLHRKCA-YQILVQVKEVLCKLSTL 226 +K + + KL LV +L + T+ Sbjct: 392 LKQYDLAIELENKLDGIYVGIAPLVGKATLLTRNPTV 428 >2C2L-A nrPDB Length = 281 Score = 111 bits (278), Expect = 6e-25, Method: Composition-based stats. Identities = 38/133 (28%), Positives = 62/133 (46%), Gaps = 5/133 (3%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR 87 A+ELK Q N F + Y A Y +AI NP A+YY NR+L YL+ + AL D R Sbjct: 4 AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRR 63 Query: 88 AIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDK-DAKMKYQECSKIVKQK 146 A+ELD + +K ++ + + + A+ + + + + + +I K+K Sbjct: 64 ALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKK 123 Query: 147 AFERAIAGDEHRR 159 + E RR Sbjct: 124 RWNSI----EERR 132 >1G5B-A nrPDB Length = 221 Score = 89.8 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 6/78 (7%) Query: 228 ETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLF 287 + + I V GD HG + +L+N + G ++ + I GD VDRG+ +VE Sbjct: 6 KIDGSKYRNIWVVGDLHGCYTNLMNKLDTIGFDNKKDLLISVGDLVDRGAENVEC----- 60 Query: 288 GFKLLYPDHFHLLRGNHE 305 +L+ F +RGNHE Sbjct: 61 -LELITFPWFRAVRGNHE 77 >4CGU-A nrPDB Length = 112 Score = 88.6 bits (218), Expect = 6e-18, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 6/95 (6%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGD 84 + + E+ K Q N FK Y A+ Y Q I P N + Y N+++A ++ Y A+ Sbjct: 2 MSQFEKQKEQGNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQM 61 Query: 85 ATRAIELDKKY------IKGYYRRAASNMALGKFR 113 + + K YR + A+G + Sbjct: 62 CQQGLRYTSTAEHVAIRSKLQYRLELAQGAVGSVQ 96 >2IF4-A nrPDB Length = 338 Score = 84.0 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 33/158 (20%), Positives = 59/158 (37%), Gaps = 20/158 (12%) Query: 12 AEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAI-------- 63 R + E + A+ K N FK + E A++ Y AI + + Sbjct: 163 EGKARSDMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQ 222 Query: 64 ---------YYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRA 114 + N + ++ + Y A+G + ++K K +RR + LG+ + Sbjct: 223 DMALAVKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDS 282 Query: 115 ALRDYETVVKVKPNDKDAKMK---YQECSKIVKQKAFE 149 A D+ K P+DK + + E K + QK E Sbjct: 283 ARDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKE 320 >1W3B-A nrPDB Length = 388 Score = 83.6 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 39/117 (33%), Gaps = 2/117 (1%) Query: 37 DYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYI 96 Y++ + AI Y +AIEL P Y N + A A A+ L + Sbjct: 246 VYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 305 Query: 97 KGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIA 153 A G A+R Y ++V P A + +Q + A+ Sbjct: 306 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ--QQGKLQEALM 360 Score = 76.3 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 51/155 (32%), Gaps = 9/155 (5%) Query: 10 ECAEPPRDEPPAEGTLKR----AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYY 65 +C R + +K+ AE N Y + + AI+ Y A+ L P Y Sbjct: 45 QCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGY 104 Query: 66 GNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKV 125 N + A + A+ A++ + ALG+ A Y ++ Sbjct: 105 INLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIET 164 Query: 126 KPNDKDAKMKYQECSKIVKQK-----AFERAIAGD 155 +PN A + FE+A+ D Sbjct: 165 QPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLD 199 Score = 72.0 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 43/114 (37%), Gaps = 7/114 (6%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR 87 A LK + + A Y+ A+ L P++A N + A+ + Sbjct: 278 ANALKEKGSVA-------EAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRK 330 Query: 88 AIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSK 141 A+E+ ++ + A+ GK + AL Y+ +++ P DA K Sbjct: 331 ALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLK 384 Score = 71.6 bits (174), Expect = 7e-13, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 38/114 (33%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR 87 A + + AI + +A+ L+P+ Y N + A+ R Sbjct: 169 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR 228 Query: 88 AIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSK 141 A+ L + + A G A+ Y ++++P+ DA K Sbjct: 229 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALK 282 Score = 68.6 bits (166), Expect = 7e-12, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 2/120 (1%) Query: 33 TQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELD 92 N +A+ ++ A+ Y +A+ L+P++A+ +GN + Y A+ RAIEL Sbjct: 208 NLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQ 267 Query: 93 KKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAI 152 + Y A + G A Y T +++ P D+ + +Q E A+ Sbjct: 268 PHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKR--EQGNIEEAV 325 Score = 48.5 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 28/78 (35%), Gaps = 1/78 (1%) Query: 1 MAMAEGERTECAEPPRDEPPAEGTL-KRAEELKTQANDYFKAKDYENAIKFYSQAIELNP 59 +A + E+ E R A + A A+ + + A+ Y +AI ++P Sbjct: 311 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 370 Query: 60 SNAIYYGNRSLAYLRTEC 77 + A Y N + Sbjct: 371 TFADAYSNMGNTLKEMQD 388 >5MGX-E nrPDB Length = 290 Score = 74.0 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 29/163 (17%), Positives = 61/163 (37%), Gaps = 18/163 (11%) Query: 8 RTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAI---- 63 +T P + + + A + N +++ D+ A Y AI+ S+A Sbjct: 111 KTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMT 170 Query: 64 -------------YYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALG 110 N + + L+ + Y AL + +E IK +R+ G Sbjct: 171 FEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQG 230 Query: 111 KFRAALRDYETVVKVKPNDKDAKMKYQE-CSKIVKQKAFERAI 152 ++ A+ +K++P++K + + K Q++ E A+ Sbjct: 231 EYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETAL 273 >6B85-J nrPDB Length = 223 Score = 70.9 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 23/95 (24%), Positives = 40/95 (42%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKK 94 + K K + A + Y +AIEL P++A + + A +AIELD + Sbjct: 122 GSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPE 181 Query: 95 YIKGYYRRAASNMALGKFRAALRDYETVVKVKPND 129 + + LG+ A Y+ +++ PND Sbjct: 182 DAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 Score = 69.3 bits (168), Expect = 4e-12, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 50/122 (40%), Gaps = 3/122 (2%) Query: 47 AIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASN 106 A + Y +AIEL+P++A+ + + + A +AIEL + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 107 MALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLD 166 LG+ A Y+ +++ P D +A + K++++ A + +D D Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEAWKELG---KVLEKLGRLDEAAEAYKKAIELDPND 216 Query: 167 IE 168 +E Sbjct: 217 LE 218 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 33/96 (34%), Gaps = 10/96 (10%) Query: 4 AEGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAI 63 AE + P D A K K + A + Y +AIEL+P +A Sbjct: 135 AEAYKKAIELKPND----------ASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAE 184 Query: 64 YYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGY 99 + + A +AIELD ++ + Sbjct: 185 AWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLEHH 220 >2DFJ-A nrPDB Length = 280 Score = 68.6 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 42/176 (23%), Positives = 69/176 (39%), Gaps = 20/176 (11%) Query: 239 VCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298 + GD HG + +L+ + + GD V RG S++V+ + D Sbjct: 5 LIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLG----DSVR 60 Query: 299 LLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFS-----EVFEWL---PLAQCINGKVLI 350 L+ GNH+ ++ + F G + K ++ L E+ WL PL Q K L+ Sbjct: 61 LVLGNHD---LHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLV 117 Query: 351 M-HGGLFSE-DGVTLDDI-RKIERNRQPPDSGPMCDLLWSDPQPQNGRSVSKRGVS 403 M H G+ + D T + R +E D ++ D N S RG+ Sbjct: 118 MAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGD--MPNNWSPELRGLG 171 >2Y4T-A nrPDB Length = 450 Score = 65.1 bits (157), Expect = 7e-11, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 56/145 (38%), Gaps = 4/145 (2%) Query: 23 GTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYY----GNRSLAYLRTECY 78 +K+ +L A + + Y +A Y ++ PS A Y + + E Sbjct: 252 KQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKP 311 Query: 79 GYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQE 138 A+ + ++++ + RA + + + A++DYET + ND+ + ++ Sbjct: 312 VEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREGLEK 371 Query: 139 CSKIVKQKAFERAIAGDEHRRSVVD 163 +++KQ +R+ Sbjct: 372 AQRLLKQSQKRDYYKILGVKRNAKK 396 Score = 59.3 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 3/125 (2%) Query: 23 GTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYAL 82 ++ E+ A +A+ + A++ +P N I Y R+ +L AL Sbjct: 21 QSMADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAAL 80 Query: 83 GDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP---NDKDAKMKYQEC 139 D T+ I+L + +R + GK A D++ V+K P +K+A+ + + Sbjct: 81 PDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKS 140 Query: 140 SKIVK 144 ++ + Sbjct: 141 DEMQR 145 Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Query: 68 RSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP 127 L AL A++ D YYRRA +A+GK +AAL D V+++K Sbjct: 32 LGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKM 91 Query: 128 NDKDAKMKYQECSKIVKQKAFERA 151 + A+++ ++KQ + A Sbjct: 92 DFTAARLQRGHL--LLKQGKLDEA 113 >5G04-F nrPDB Length = 824 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 51/130 (39%), Gaps = 3/130 (2%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKK 94 N + ++++ AIKF+ +AI+++P+ A Y ++ TE AL AI ++ + Sbjct: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 Query: 95 YIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAG 154 + +Y KF A ++ + + P +K+ Sbjct: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK---SEKALD 690 Query: 155 DEHRRSVVDS 164 ++ V+D Sbjct: 691 TLNKAIVIDP 700 Score = 59.3 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 51/113 (45%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKK 94 Y+K + + A + +A+++NP +++ + + + AL +AI +D K Sbjct: 642 GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPK 701 Query: 95 YIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKA 147 + RA+ A K+++AL++ E + ++ P + + K + Q Sbjct: 702 NPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 754 Score = 52.8 bits (125), Expect = 4e-07, Method: Composition-based stats. Identities = 20/128 (15%), Positives = 51/128 (39%), Gaps = 2/128 (1%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKK 94 +++ ++ + A+ + AI +NP + + + Y + E + A +A++++ + Sbjct: 608 GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 Query: 95 YIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAG 154 AL K AL + + P + K+ S + + ++ A+ Sbjct: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP--LCKFHRASVLFANEKYKSALQE 725 Query: 155 DEHRRSVV 162 E + +V Sbjct: 726 LEELKQIV 733 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 29/204 (14%), Positives = 73/204 (35%), Gaps = 17/204 (8%) Query: 52 SQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGK 111 +++ ++ + + + A+ RAI++D Y Y + + Sbjct: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEE 616 Query: 112 FRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQ-----KAFERAIAGDEHRRSVVDSLD 166 AL + ++V P +A ++ F++A+ + ++ + Sbjct: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 Query: 167 IESMTIEDEYSGPKLEDGKVTITFMKDLMQW------YKDQKKLHRKCAYQILVQVKEVL 220 + ++ + + I L ++ + ++K K A Q L ++K+++ Sbjct: 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKY---KSALQELEELKQIV 733 Query: 221 CKLSTLVETTLKETEKITVCGDTH 244 K S + K +K+ G TH Sbjct: 734 PKESLVYFLIGKVYKKL---GQTH 754 Score = 35.4 bits (80), Expect = 0.056, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 37/90 (41%) Query: 34 QANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDK 93 +A+ F + Y++A++ + ++ P ++ Y Y + AL + + A++LD Sbjct: 709 RASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 Query: 94 KYIKGYYRRAASNMALGKFRAALRDYETVV 123 K + A L + E ++ Sbjct: 769 KGANNQIKEAIDKRYLPDDEEPITQEEQIM 798 >5JHE-A nrPDB Length = 397 Score = 62.8 bits (151), Expect = 4e-10, Method: Composition-based stats. Identities = 36/145 (24%), Positives = 60/145 (41%), Gaps = 22/145 (15%) Query: 23 GTLKRAEELKTQANDYFKAKDYENAIKFYSQAI----ELNPSNAI--------------Y 64 L+ A +K FK KDY NA Y +++ E P + Sbjct: 239 KALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKI 298 Query: 65 YGNRSLAYLRTECYGYALGDATRAIELDK----KYIKGYYRRAASNMALGKFRAALRDYE 120 Y N SL E Y A+ AT +E+D K YYRR S + + AL+DY Sbjct: 299 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 358 Query: 121 TVVKVKPNDKDAKMKYQECSKIVKQ 145 + P+D+ + + + ++++++ Sbjct: 359 FCKEKNPDDEVIEQRIEYVNRLIEE 383 >5G05-C nrPDB Length = 597 Score = 62.4 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 35/187 (18%), Positives = 72/187 (38%), Gaps = 12/187 (6%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKK 94 N Y +E A ++ +A++LNP + Y+ + A+ AIE++K+ Sbjct: 338 GNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKR 397 Query: 95 YIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQK------AF 148 + +Y + L L Y +++PND + EC + + Q + Sbjct: 398 DYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYW 457 Query: 149 ERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKC 208 GD + ++V + E E + + I +++D+ + + L Sbjct: 458 RAYAVGDVEKMALVKLAKLHEQLTESE------QAAQCYIKYIQDIYSCGEIVEHLEEST 511 Query: 209 AYQILVQ 215 A++ L Q Sbjct: 512 AFRYLAQ 518 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 30/77 (38%) Query: 68 RSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKP 127 Y + A RA++L+ +Y+ + M + AA++ Y ++V Sbjct: 337 IGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNK 396 Query: 128 NDKDAKMKYQECSKIVK 144 D A + +I+K Sbjct: 397 RDYRAWYGLGQTYEILK 413 >5FZQ-A nrPDB Length = 131 Score = 60.5 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 2/118 (1%) Query: 31 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 90 L AN + E AIK+ +A+ L+P+N N + + A+ +A+ Sbjct: 8 LSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVS 67 Query: 91 LDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAF 148 LD IK A GK A++ V + DK AK + ++K+ Sbjct: 68 LDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLI--DKAAKGSTLHKNAAARRKSR 123 >5KHR-J nrPDB Length = 620 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 52/149 (34%), Gaps = 12/149 (8%) Query: 33 TQANDYFKAKDYENAIKFYSQAIE----------LNPSNAIYYGNRSLAYLRTECYGYAL 82 F+ +++ A K++ A+E ++ + N + + Y AL Sbjct: 407 EVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLL-NNLGHVCRKLKKYAEAL 465 Query: 83 GDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKI 142 +A+ L + Y + +G F A+ + T + ++ +D + C ++ Sbjct: 466 DYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEM 525 Query: 143 VKQKAFERAIAGDEHRRSVVDSLDIESMT 171 E I D + D+ +M Sbjct: 526 YI-GDSEAYIGADIKDKLKCYDFDVHTMK 553 Score = 36.2 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 25/66 (37%) Query: 31 LKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 90 L + K K Y A+ ++ QA+ L P NA Y + + A+ A+ Sbjct: 448 LNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALG 507 Query: 91 LDKKYI 96 L + Sbjct: 508 LRRDDT 513 >5VJW-A nrPDB Length = 309 Score = 48.9 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 25/82 (30%), Positives = 38/82 (46%), Gaps = 7/82 (8%) Query: 231 LKETEKITVC-GDTHGQFYDLLNI-FELNGLPSETN----PYIFNGDFVDRGSFSVEVIL 284 + + + +C GD HG L N+ L ++ IF GD+ DRG + +VI Sbjct: 1 MAQKPRTVICVGDIHGYISKLNNLWLNLQSAIDPSDFSSALVIFLGDYCDRGPETRKVID 60 Query: 285 TLFGFKLLYPDHFHL-LRGNHE 305 L +PD H+ L GNH+ Sbjct: 61 FLISLPEKHPDQTHVFLAGNHD 82 >6C95-A nrPDB Length = 866 Score = 45.8 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 52/150 (34%), Gaps = 7/150 (4%) Query: 41 AKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYY 100 K Y+ AIK Y A++ + N + SL ++ + ++L + Sbjct: 93 DKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWI 152 Query: 101 RRAASNMALGKFRAA---LRDYETVVKVKPNDKD-AKMKYQECSKIVKQKA---FERAIA 153 A + L + A L ++ + P+ D + V ++A E Sbjct: 153 GYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEH 212 Query: 154 GDEHRRSVVDSLDIESMTIEDEYSGPKLED 183 + + + D L +E E +LED Sbjct: 213 LCTYEKQICDKLAVEETKGELLLQLCRLED 242 >5WQL-B nrPDB Length = 278 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 44/127 (34%) Query: 26 KRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDA 85 +RA+ L + Y A +SQA+ + P + + + + A Sbjct: 44 ERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAF 103 Query: 86 TRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQ 145 +ELD Y + R + G+ + A D + PND + + + + Sbjct: 104 DSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDE 163 Query: 146 KAFERAI 152 K + + Sbjct: 164 KQAKEVL 170 >5OJF-A nrPDB Length = 314 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 44/139 (31%), Gaps = 26/139 (18%) Query: 37 DYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYGYALGDATRA 88 Y Y++A + A+ + P+ A N ++ Y + Y A RA Sbjct: 79 VYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRA 138 Query: 89 IELD--------KKYIKGYYRRAASNMALGKFRAALRDYETVVKVK-----PNDKDA--- 132 +E+ K A GK Y +++ P+D + Sbjct: 139 LEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKT 198 Query: 133 KMKYQECSKIVKQKAFERA 151 K C +KQ ++ A Sbjct: 199 KNNLASC--YLKQGKYQDA 215 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 37/112 (33%), Gaps = 16/112 (14%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYG 79 A L A Y K Y+ A +A+E+ P A N +L Sbjct: 112 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAE 171 Query: 80 YALGDATRAIEL--------DKKYIKGYYRRAASNMALGKFRAALRDYETVV 123 RA+E+ D K A+ + GK++ A Y+ ++ Sbjct: 172 EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 223 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 24/70 (34%), Gaps = 1/70 (1%) Query: 21 AEGTLKRAEELKTQANDYFKAKDYENAIKFY-SQAIELNPSNAIYYGNRSLAYLRTECYG 79 A+ A + Q Y A++ Y ++ +P+ A N + YL+ Y Sbjct: 154 AKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQ 213 Query: 80 YALGDATRAI 89 A + Sbjct: 214 DAETLYKEIL 223 >5OJ8-A nrPDB Length = 255 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 46/135 (34%), Gaps = 26/135 (19%) Query: 41 AKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYGYALGDATRAIELD 92 Y++A + A+ + P+ A N ++ Y + Y A RA+E+ Sbjct: 105 QNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIR 164 Query: 93 --------KKYIKGYYRRAASNMALGKFRAALRDYETVVKVK-----PNDKDA---KMKY 136 K A GK+ Y+ +++ P+D + K Sbjct: 165 EKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNL 224 Query: 137 QECSKIVKQKAFERA 151 C +KQ F++A Sbjct: 225 ASC--YLKQGKFKQA 237 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 38/112 (33%), Gaps = 16/112 (14%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYG 79 A L A Y K Y+ A +A+E+ P A N +L Y Sbjct: 134 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYE 193 Query: 80 YALGDATRAIEL--------DKKYIKGYYRRAASNMALGKFRAALRDYETVV 123 RA+E+ D K A+ + GKF+ A Y+ ++ Sbjct: 194 EVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 245 >3ZFW-A nrPDB Length = 263 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 25/139 (17%), Positives = 44/139 (31%), Gaps = 26/139 (18%) Query: 37 DYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYGYALGDATRA 88 Y Y++A + A+ + P+ A N ++ Y + Y A RA Sbjct: 32 VYRDQNKYKDAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRA 91 Query: 89 IELD--------KKYIKGYYRRAASNMALGKFRAALRDYETVVKVK-----PNDKDA--- 132 +E+ K A GK Y +++ P+D + Sbjct: 92 LEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKT 151 Query: 133 KMKYQECSKIVKQKAFERA 151 K C +KQ ++ A Sbjct: 152 KNNLASC--YLKQGKYQDA 168 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 37/112 (33%), Gaps = 16/112 (14%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYG 79 A L A Y K Y+ A +A+E+ P A N +L Sbjct: 65 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAE 124 Query: 80 YALGDATRAIEL--------DKKYIKGYYRRAASNMALGKFRAALRDYETVV 123 RA+E+ D K A+ + GK++ A Y+ ++ Sbjct: 125 EVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEIL 176 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 13/70 (18%), Positives = 24/70 (34%), Gaps = 1/70 (1%) Query: 21 AEGTLKRAEELKTQANDYFKAKDYENAIKFY-SQAIELNPSNAIYYGNRSLAYLRTECYG 79 A+ A + Q Y A++ Y ++ +P+ A N + YL+ Y Sbjct: 107 AKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQ 166 Query: 80 YALGDATRAI 89 A + Sbjct: 167 DAETLYKEIL 176 >3NF1-A nrPDB Length = 311 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 47/139 (33%), Gaps = 26/139 (18%) Query: 37 DYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYGYALGDATRA 88 Y Y++A + A+ + P+ A N ++ Y + Y A RA Sbjct: 78 VYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRA 137 Query: 89 IELD--------KKYIKGYYRRAASNMALGKFRAALRDYETVVKVK-----PNDKDA--- 132 +E+ K A GK+ Y+ +++ P+D + Sbjct: 138 LEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKT 197 Query: 133 KMKYQECSKIVKQKAFERA 151 K C +KQ F++A Sbjct: 198 KNNLASC--YLKQGKFKQA 214 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 38/112 (33%), Gaps = 16/112 (14%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYG 79 A L A Y K Y+ A +A+E+ P A N +L Y Sbjct: 111 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYE 170 Query: 80 YALGDATRAIEL--------DKKYIKGYYRRAASNMALGKFRAALRDYETVV 123 RA+E+ D K A+ + GKF+ A Y+ ++ Sbjct: 171 EVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 222 >6FUZ-A nrPDB Length = 337 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 27/139 (19%), Positives = 47/139 (33%), Gaps = 26/139 (18%) Query: 37 DYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYGYALGDATRA 88 Y Y++A + A+ + P+ A N ++ Y + Y A RA Sbjct: 64 VYRDQNKYKDAANLLNDALAIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRA 123 Query: 89 IELD--------KKYIKGYYRRAASNMALGKFRAALRDYETVV-----KVKPNDKDA--- 132 +E+ K A GK+ Y+ + K+ P+D + Sbjct: 124 LEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKT 183 Query: 133 KMKYQECSKIVKQKAFERA 151 K C +KQ F++A Sbjct: 184 KNNLASC--YLKQGKFKQA 200 Score = 37.4 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 37/112 (33%), Gaps = 16/112 (14%) Query: 28 AEELKTQANDYFKAKDYENAIKFYSQAIELN--------PSNAIYYGNRSLAYLRTECYG 79 A L A Y K Y+ A +A+E+ P A N +L Y Sbjct: 97 AATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYE 156 Query: 80 YALGDATRAIEL--------DKKYIKGYYRRAASNMALGKFRAALRDYETVV 123 RA+ + D K A+ + GKF+ A Y+ ++ Sbjct: 157 EVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAETLYKEIL 208 >5NNP-A nrPDB Length = 745 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 38/104 (36%) Query: 37 DYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYI 96 +++ K Y+ +K Q ++ NP + ++L A A A+ +D K Sbjct: 19 RHYEDKQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSY 78 Query: 97 KGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECS 140 ++ F A++ Y+ +K++P + Sbjct: 79 ICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQ 122 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 34/163 (20%), Positives = 59/163 (36%), Gaps = 17/163 (10%) Query: 6 GER-TECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFY-SQAIELNPSN-- 61 GER A+ +G LK +D FK + + + Y ++ + PS+ Sbjct: 303 GERFRTTAKAYLTLMFDKGVPSTFANLKHLYSDSFKKETLASLAEEYLNEYVNARPSDNQ 362 Query: 62 -----------AIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALG 110 A+YY + Y + AL +AIELD K + + +A G Sbjct: 363 ADGDGSKGKGAALYYLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDFHMTKARIFKHQG 422 Query: 111 KFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIA 153 A + + P D+ K + ++ E+A+A Sbjct: 423 DLAKAAETMDYARSLDPKDRYINSKAAKYQ--LRNNENEKALA 463 >5G04-X nrPDB Length = 599 Score = 42.0 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 28/62 (45%) Query: 78 YGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQ 137 Y AL +AI+L+ ++ + A+ +G+ + A+ + +++ P D Sbjct: 355 YSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLI 414 Query: 138 EC 139 EC Sbjct: 415 EC 416 Score = 35.8 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 38/121 (31%), Gaps = 3/121 (2%) Query: 34 QANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDK 93 + + AI + +AI L P Y YL + A+ A + Sbjct: 379 KGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLG 438 Query: 94 KYIKGYYRRAAS-NMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAI 152 + A A + + +P+ A +K E + +++ +E I Sbjct: 439 ANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQRPDYIKAVVKKAEL--LSREQKYEDGI 496 Query: 153 A 153 A Sbjct: 497 A 497 >5ZYQ-A nrPDB Length = 320 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 26/62 (41%), Gaps = 1/62 (1%) Query: 39 FKAKDYENAIKFYSQAIELNPSNAIYYG-NRSLAYLRTECYGYALGDATRAIELDKKYIK 97 F KDY A+ +Y +A+ NP +++ A +RA+EL+ K + Sbjct: 174 FNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVG 233 Query: 98 GY 99 Sbjct: 234 AL 235 Score = 35.1 bits (79), Expect = 0.072, Method: Composition-based stats. Identities = 11/91 (12%), Positives = 29/91 (31%), Gaps = 3/91 (3%) Query: 38 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97 + + A + + +P+N ++ + Y AL +A+ + Sbjct: 139 LLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNP-GCP 197 Query: 98 GYYRRAASN--MALGKFRAALRDYETVVKVK 126 R + + L K A + +++ Sbjct: 198 AEVRLGMGHCFVKLNKLEKARLAFSRALELN 228 >2QJC-A nrPDB Length = 262 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 30/72 (41%), Gaps = 6/72 (8%) Query: 234 TEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLY 293 T ++ + GD HG L ++ ++ + GD V++G S V+ L Sbjct: 18 TGRVIIVGDIHGCRAQLEDLLRAVSFKQGSDTLVAVGDLVNKGPDSFGVVRLLKRLGA-- 75 Query: 294 PDHFHLLRGNHE 305 + + GNH+ Sbjct: 76 ----YSVLGNHD 83 >5AEM-A nrPDB Length = 447 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 32/194 (16%), Positives = 64/194 (32%), Gaps = 39/194 (20%) Query: 29 EELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRS------------------L 70 +L +QAN+ F D + A + +++ I+ + N Y Sbjct: 10 AQLLSQANEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLA 69 Query: 71 AYLRTECYG----------------YALGDATRAIELDKKYIKGYYRRAASNMALGKFRA 114 A+L + A+ +R I L+ + YRR+ G+ Sbjct: 70 AHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLAR 129 Query: 115 ALRDYETVVKVKPNDKDAKMKYQEC----SKIVKQKA-FERAIAGDEHRRSVVDSLDIES 169 AL ++ + P D + + +I + + + RR + + + Sbjct: 130 ALDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIELYMKVFNANVERREAILAALENA 189 Query: 170 MTIEDEYSGPKLED 183 + DE S + ED Sbjct: 190 LDSSDEESAAEGED 203 Score = 36.2 bits (82), Expect = 0.036, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 26/80 (32%), Gaps = 1/80 (1%) Query: 33 TQANDYFKAKDYENAIKFYSQAIELNP-SNAIYYGNRSLAYLRTECYGYALGDATRAIEL 91 A +A+ Y+ AI F++ + L + + Y E Y A AI+ Sbjct: 353 EAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYELAIKS 412 Query: 92 DKKYIKGYYRRAASNMALGK 111 + + A L Sbjct: 413 EPDDLDIRVSLAEVYYRLND 432 >4UZY-A nrPDB Length = 651 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 24/58 (41%) Query: 33 TQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIE 90 FK +E A + ++ A++ N +L Y +T+ +G AL IE Sbjct: 152 NTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIALCYYKTKQFGPALKHLAEIIE 209 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 32/104 (30%), Gaps = 3/104 (2%) Query: 37 DYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYI 96 K + + AI+ ++ P + Y T Y A + + L Sbjct: 26 TLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYPSNE 85 Query: 97 KGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECS 140 A S G + A + VVKV+ + K CS Sbjct: 86 DYKLYYAQSLYKGGMYPEA---SKAVVKVEGHQKAVTTLLVACS 126 Score = 33.1 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 47/269 (17%), Positives = 87/269 (32%), Gaps = 51/269 (18%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIY-------------YGNRSLAYLRTECYGYA 81 Y+ Y+ A + Y Q + L PSN Y Y S A ++ E + A Sbjct: 58 GYCYYYTGQYDMASQMYEQLVTLYPSNEDYKLYYAQSLYKGGMYPEASKAVVKVEGHQKA 117 Query: 82 LGD--------------ATRAIELD-KKYIKGYYRRAASNMALGKFRAALRDYETVVKVK 126 + R ++ + GKF AA + + V+ Sbjct: 118 VTTLLVACSYEQDDLTGCRRQLDKCAPEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQAL 177 Query: 127 PNDKDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYS-GPKLEDGK 185 + C KQ F A+ + + + ++ +++ E S G + + Sbjct: 178 GYQPELLYNIALCYYKTKQ--FGPAL------KHLAEIIE-KAVREHPELSVGSNTDGME 228 Query: 186 VTIT----FMKD--LMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVE-----TTLKET 234 V +K+ L++ + + + + + KE L + E TL + Sbjct: 229 VRSVGNSQTLKETALIEAFNLKAAIE--YTMKNVEAAKEALTDMPPRAEEELDPVTLHNS 286 Query: 235 EKITVCGDTHGQFYDLLNIFELNGLPSET 263 I + D G F L + + P ET Sbjct: 287 ALINMDSDPTGGFKKLNFLLQSPPFPPET 315 >5ZYP-A nrPDB Length = 390 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 39 FKAKDYENAIKFYSQAIELNPS-NAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97 ++ K+Y ++K + + + +NP L + + + A+ RA++L+ K Sbjct: 194 YQKKNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDSKMAIKSWQRALQLNPKNT- 252 Query: 98 GYYRRAASNMALGKFRAAL 116 A+ + LG+FR + Sbjct: 253 ----SASILVLLGEFRESF 267 >4JHR-A nrPDB Length = 333 Score = 38.5 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 19/132 (14%), Positives = 42/132 (31%), Gaps = 24/132 (18%) Query: 33 TQANDYFKAKDYENAIKFYSQAIEL------NPSNAIYYGNRSLAYLRTECYGYALGDAT 86 N Y ++E A ++Y + + L A + Y + Y A+ Sbjct: 156 NLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHL 215 Query: 87 RAIELDKKYI------KGYYRRAASNMALGKFRAALRDYETVVKVK------------PN 128 + + + ++ + + + ALG A+ E +++ P Sbjct: 216 KHLAIAQELKDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDLEVLFQGPP 275 Query: 129 DKDAKMKYQECS 140 D+D +C Sbjct: 276 DEDFFDILVKCQ 287 Score = 38.5 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 40/107 (37%), Gaps = 12/107 (11%) Query: 45 ENAIKFYSQAIEL------NPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKY--- 95 + A+ Y + + L + +GN + + A+ + + + K++ Sbjct: 88 QAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDK 147 Query: 96 ---IKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQEC 139 + Y + + LG+F A Y+ + + KD ++ Q C Sbjct: 148 AAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSC 194 >5LJ5-S nrPDB Length = 687 Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 38/250 (15%), Positives = 86/250 (34%), Gaps = 24/250 (9%) Query: 17 DEPPAEGTLKRAEELKTQANDY-------FKAKDYENAIKFYSQAIELNPSNAIYYGNRS 69 D P A L +A L +A + K K+++ K Y + IE PS+ + Sbjct: 419 DVPKARKILGKAIGLCPKAKTFKGYIELEVKLKEFDRVRKIYEKFIEFQPSDLQIWSQYG 478 Query: 70 LAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMAL------GKFRAALRDYETVV 123 + G T A++ + ++ + + +F A + Y + Sbjct: 479 ELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITFETESQEFEKARKLYRRYL 538 Query: 124 KVKPNDKDAKMKYQECSKIVKQKAFERAIAG--DEHRRSVVDSLDIESMTIEDEYSGPKL 181 ++ + +++ E+ + +V + ++ E +T E++ K+ Sbjct: 539 ELNQYSPQSWIEFAMYQ---TSTPTEQQLLDLAKLQSENVDEDIEFE-ITDENKLEARKV 594 Query: 182 EDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLVETTLKETEKITVCG 241 + I F K+ Q +L A + + T+ + K +K+ + Sbjct: 595 FEE--AIVFFKEKD---DKQGRLSILEALKDYEETYGTELDQETVKKRFPKVIKKVRLQN 649 Query: 242 DTHGQFYDLL 251 +F D + Sbjct: 650 GVEEEFVDYI 659 >5EFR-A nrPDB Length = 446 Score = 38.1 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 65/163 (39%), Gaps = 23/163 (14%) Query: 33 TQANDYFKAKDYENAIKFYSQAIELN-----PSNAIYYGNRSLAYLRTECYGYALGDATR 87 +A +++ Y+ AI+++ ++A +Y + AY + + Y A + R Sbjct: 205 ERAMEFYNQGKYDRAIEYFKAVFTYGRTHEWAADAQFY--LARAYYQNKEYLLAASEYER 262 Query: 88 AI---ELDKKYIKGYYRRAASNMALG--------KFRAALRDYETVVKVKPNDK---DAK 133 I ++D + + Y RA L R A+ ++ + PN + DA Sbjct: 263 FIQIYQIDPRVPQAEYERAMCYYKLSPPYELDQTDTRKAIEAFQLFIDRYPNHELVDDAT 322 Query: 134 MKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEY 176 K +E + +K +E A RR + ++ + + D Y Sbjct: 323 QKIRELRAKLARKQYEAARL--YERRELYEAAAVTYEAVFDAY 363 >4HOQ-A nrPDB Length = 482 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 49/146 (33%), Gaps = 28/146 (19%) Query: 2 AMAEGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSN 61 A AEGE E L+ A + + N + A++ +A+E+ P++ Sbjct: 230 AEAEGE-KYIEEILDQISSQPYVLRYAAKFYRRKNS------WNKALELLKKALEVTPTS 282 Query: 62 AIYYGNRSLAY--------------------LRTECY-GYALGDATRAIELDKKYIKGYY 100 + + L Y L+ + A+ A+E D + Y Sbjct: 283 SFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYT 342 Query: 101 RRAASNMALGKFRAALRDYETVVKVK 126 A G++ A + ++++ Sbjct: 343 DLANMYAEGGQYSNAEDIFRKALRLE 368 Score = 31.6 bits (70), Expect = 0.83, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 33/100 (33%), Gaps = 10/100 (10%) Query: 39 FKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKG 98 F K AI Y +A+++ + + + A + T+ + + ++ Sbjct: 388 FHRKSENTAIHHYLEALKVKDRSPLR-TKLTSALKKLS---------TKRLCHNALDVQS 437 Query: 99 YYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQE 138 G+ R A YE K+ P + + E Sbjct: 438 LSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCE 477 Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 33/86 (38%), Gaps = 9/86 (10%) Query: 20 PAEGTLKRAEELKTQANDYFK--AKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTEC 77 P+ L+ E + K K Y+ A + +A+E+ P N + ++ R + Sbjct: 130 PSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDD 189 Query: 78 Y-------GYALGDATRAIELDKKYI 96 ++LG +A+ L+ Sbjct: 190 SDREGSVKSFSLGPLRKAVTLNPDNS 215 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 14/111 (12%), Positives = 32/111 (28%), Gaps = 12/111 (10%) Query: 21 AEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGY 80 AE +++ K + +Y Q E Y G + Sbjct: 77 AEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQK----YTGKIGNVCKKLSSPSN 132 Query: 81 ALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKD 131 + E D + + ++ A +E ++V+P++ + Sbjct: 133 YKLECP---ETDCEKGWALLKFGGKY-----YQKAKAAFEKALEVEPDNPE 175 >4KVO-A nrPDB Length = 731 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 36/160 (22%), Positives = 65/160 (40%), Gaps = 11/160 (6%) Query: 41 AKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYY 100 KDY A K Y A +L +N+ + +L + Y AL D A+ D ++ + Sbjct: 91 DKDYVQAAKCYINAHKLEKNNSSLLRDLALLQSQLRQY-KALADTRNALLQDNPGVRANW 149 Query: 101 R-RAASNMALGKFRAALR---DYE-TVVKVKPNDKDAKMK--YQECSKIVKQKAFERAI- 152 A + G++ +A + +E T+ + P D + + I+K+ E A Sbjct: 150 SALAVAQFLRGEYASAYKIVDAFESTINQGVPVDTQEESEAMLFMNLVILKKDGVEDAYK 209 Query: 153 -AGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFM 191 ++ V+D + E E K+E+ K TI + Sbjct: 210 HLLSIEKK-VLDRVAFLETRAEYELYLSKMEEAKSTIYLL 248 >5CQS-A nrPDB Length = 435 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 57/285 (20%), Positives = 101/285 (35%), Gaps = 47/285 (16%) Query: 1 MAMAEGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQA------ 54 +A+ ++++ PR+ P L+ E L+ + +YE A++ S+ Sbjct: 22 LALLVAQKSQMD--PREYLPFLQELQDNEPLRRKFLIDDYLGNYEKALEHLSEIDKDGNV 79 Query: 55 ----IELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALG 110 I+ S+ +Y +L +E + + ++ Y A + LG Sbjct: 80 SEEVIDYVESHDLYKHGLALYRYDSEKQNVIYNIYAKHLSSNQMYTDA----AVAYEMLG 135 Query: 111 KFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESM 170 K + A+ Y++ + ++E I QK E SV + L I S+ Sbjct: 136 KLKEAMGAYQSAKR-----------WREAMSIAVQK-------FPEEVESVAEEL-ISSL 176 Query: 171 TIEDEYSGP---KLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLSTLV 227 T E Y +LE + +K+ + Y + I + E+L + +V Sbjct: 177 TFEHRYVDAADIQLE----YLDNVKEAVALYCKAYRYDIASLVAIKAKKDELLEE---VV 229 Query: 228 ETTLKETEKITV--CGDTHGQFYDLLNIFELNGLPSETNPYIFNG 270 + L E I D GQ L E NPY F G Sbjct: 230 DPGLGEGFGIIAELLADCKGQINSQLRRLRELRAKKEENPYAFYG 274 >4YG8-B nrPDB Length = 754 Score = 36.6 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 30/69 (43%) Query: 14 PPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYL 73 PPRD A ++ L Q N DYE A+ + + EL + + N + ++ Sbjct: 323 PPRDADSARLMNCMSDLLNIQTNFLLNRGDYELALGVSNTSTELALDSFESWYNLARCHI 382 Query: 74 RTECYGYAL 82 + E Y AL Sbjct: 383 KKEEYEKAL 391 >4YMR-A nrPDB Length = 144 Score = 35.1 bits (79), Expect = 0.081, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 22/59 (37%), Gaps = 9/59 (15%) Query: 42 KDYENAIKFYSQAIELN--------PSNAIY-YGNRSLAYLRTECYGYALGDATRAIEL 91 Y A+ ++ A +L P + ++ + E G A + +A++L Sbjct: 25 GLYREALALWANAWQLQTQLGTPSGPDRPLLTLAGLAVCHQELEDPGEARACSEKALQL 83 >4ABN-A nrPDB Length = 474 Score = 34.7 bits (78), Expect = 0.098, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 3/77 (3%) Query: 45 ENAIKFYSQAIELN---PSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYR 101 + A+ Y+QA +++ SN + NR+ + E YG AL ++A LD + + R Sbjct: 238 QQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEGFSQAAALDPAWPEPQQR 297 Query: 102 RAASNMALGKFRAALRD 118 L + + L Sbjct: 298 EQQLLEFLSRLTSLLES 314 Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 25/190 (13%), Positives = 64/190 (33%), Gaps = 20/190 (10%) Query: 45 ENAIKFYSQAIELNPSNAIYYGNRSLAYLRT--------ECYGYALGDATRAIELD---K 93 ++++ A++++ + + AYL + AL +A ++D Sbjct: 196 MDSVRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKAS 255 Query: 94 KYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIA 153 + RA + + AL + + P + + Q ++++ + ++ Sbjct: 256 SNPDLHLNRATLHKYEESYGEALEGFSQAAALDPAWPEPQ---QREQQLLEFLSRLTSLL 312 Query: 154 GDEHRRSVVDSLDIESM--TIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQ 211 + + ++SM ++ + GP DG+ + + K L Sbjct: 313 ESKGK---TKPKKLQSMLGSLRPAHLGP-CGDGRYQSASGQKMTLELKPLSTLQPGVNSG 368 Query: 212 ILVQVKEVLC 221 +V K V Sbjct: 369 TVVLGKVVFS 378 >5UDI-A nrPDB Length = 479 Score = 34.7 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 19/144 (13%), Positives = 46/144 (31%), Gaps = 21/144 (14%) Query: 5 EGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIY 64 + E E E + + A Y + + A++ +A++ P++ + Sbjct: 229 QDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLL 288 Query: 65 YGNRSLAYL--------------------RTEC-YGYALGDATRAIELDKKYIKGYYRRA 103 + L Y + + A+ A+E + + A Sbjct: 289 HHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLA 348 Query: 104 ASNMALGKFRAALRDYETVVKVKP 127 + G R A +++ ++ +KP Sbjct: 349 RMYIEAGNHRKAEENFQKLLCMKP 372 Score = 33.5 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 39/125 (31%), Gaps = 12/125 (9%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGD 84 L + LK Q + K+ + + N + + +GN + Y A Sbjct: 59 LAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTY 118 Query: 85 ATRAIELDKKYIKGYYRR------------AASNMALGKFRAALRDYETVVKVKPNDKDA 132 + + KK + R A + A +E V++V P + ++ Sbjct: 119 LDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPES 178 Query: 133 KMKYQ 137 Y Sbjct: 179 SAGYA 183 Score = 30.8 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 38/116 (32%), Gaps = 17/116 (14%) Query: 20 PAEGTLKRAEELKTQANDYFK--AKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTEC 77 P ++ E + K K+YE A + + +E++P N +++ R + Sbjct: 132 PFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDG 191 Query: 78 YGYALGDA--------TRAIELDKK--YIKGYYRR-----AASNMALGKFRAALRD 118 + A + +A+ L+ YIK AL + Sbjct: 192 FKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 247 >2W42-A nrPDB Length = 427 Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 18/83 (21%) Query: 166 DIESMTIEDEYSGPKLEDGKVTITFMKDLMQWYKDQKKLHRKCAYQILVQVKEVLCKLST 225 D+E +T+ PK++DG+ I +K+ ++ K Q+ + R Y IL Sbjct: 245 DVEKLTLHVSGKRPKMKDGETKI--LKETVEELKKQEMVSRDVKYAILH----------- 291 Query: 226 LVETTLKETEKITVCGDTHGQFY 248 L ET V GD + +F+ Sbjct: 292 -----LNETHPFWVMGDPNNRFH 309 >4I1A-A nrPDB Length = 391 Score = 33.5 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 45/119 (37%), Gaps = 13/119 (10%) Query: 43 DYENAIKFYSQAIELNPSN------AIYYGNRSLAYLRTECYGYALGDATRAIELDKKY- 95 +YE A++ + +++E++ + A+ + N + Y + Y A A+E+ +K Sbjct: 199 EYERALEQFLKSLEISKESNIEHLIAMSHMNIGICYDELKEYKKASQHLILALEIFEKSK 258 Query: 96 ----IKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFER 150 K + + AL + + DK +Y KI++ F Sbjct: 259 HSFLTKTLFTLTYVEAKQQNYNVALIYFRKGRFIA--DKSDDKEYSAKFKILEGLFFSD 315 Score = 28.5 bits (62), Expect = 6.3, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 51/145 (35%), Gaps = 31/145 (21%) Query: 2 AMAEGERTECAEPPRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSN 61 M E R E AE L E+ +A +FK + + +Y + Sbjct: 110 GMYEFRRKELISAISAYRIAESKLSEVEDEIEKAEFFFK----VSYVYYYMK----QTYF 161 Query: 62 AIYYGNRSLA----------------------YLRTECYGYALGDATRAIELDKKYIKGY 99 ++ Y NR+L + + Y AL +++E+ K+ + Sbjct: 162 SMNYANRALKIFREYEEYAVQTVRCQFIVAGNLIDSLEYERALEQFLKSLEISKESNIEH 221 Query: 100 YRRAASNMALGKFRAALRDYETVVK 124 A S+M +G L++Y+ + Sbjct: 222 L-IAMSHMNIGICYDELKEYKKASQ 245 >5JZ6-A nrPDB Length = 429 Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 33/115 (28%), Gaps = 11/115 (9%) Query: 33 TQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLA-------YLRTECYGYALGDA 85 A K E A+ + + + P + ++ E A+ Sbjct: 17 DAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETY 76 Query: 86 TRAIELDKKYIK----GYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKY 136 L RR+ LG R +L + +V++ PND K Sbjct: 77 QEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDL 131 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 21/58 (36%) Query: 96 IKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIA 153 IK A GK A+ ++ +V+ P A+ +C + +K + Sbjct: 12 IKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVL 69 >4HOU-A nrPDB Length = 273 Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 39/125 (31%), Gaps = 12/125 (9%) Query: 25 LKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGD 84 L + LK Q + K+ + + N + + +GN + Y A Sbjct: 52 LAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTY 111 Query: 85 ATRAIELDKKYIKGYYRR------------AASNMALGKFRAALRDYETVVKVKPNDKDA 132 + + KK + R A + A +E V++V P + ++ Sbjct: 112 LDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPES 171 Query: 133 KMKYQ 137 Y Sbjct: 172 SAGYA 176 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 38/116 (32%), Gaps = 17/116 (14%) Query: 20 PAEGTLKRAEELKTQANDYFK--AKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTEC 77 P ++ E + K K+YE A + + +E++P N +++ R + Sbjct: 125 PFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDG 184 Query: 78 YGYALGDA--------TRAIELDKK--YIKGYYRR-----AASNMALGKFRAALRD 118 + A + +A+ L+ YIK AL + Sbjct: 185 FKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALAN 240 >4G1T-A nrPDB Length = 472 Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 34/103 (33%), Gaps = 4/103 (3%) Query: 45 ENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR----AIELDKKYIKGYY 100 +NAI QAI LNP N +L + G G+ + A+E Sbjct: 192 QNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLR 251 Query: 101 RRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIV 143 A + A+ + ++ PN+ + C + Sbjct: 252 SAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAK 294 >6N3Q-F nrPDB Length = 193 Score = 32.7 bits (73), Expect = 0.38, Method: Composition-based stats. Identities = 6/56 (10%), Positives = 18/56 (32%) Query: 42 KDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 97 + A++ + + ++ L+ + A R + L + +K Sbjct: 120 GKHLEALQDLDFLLGTGLIQPDVFVRKADCLLKLRQWEEARATCERGLALAPEDMK 175 >5XJC-J nrPDB Length = 848 Score = 32.7 bits (73), Expect = 0.41, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 38/90 (42%) Query: 42 KDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYR 101 K+ + A Y +A++++ N + + ++ +A RAI + + +Y+ Sbjct: 256 KEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYK 315 Query: 102 RAASNMALGKFRAALRDYETVVKVKPNDKD 131 LG A + +E ++ +P ++ Sbjct: 316 YTYMEEMLGNVAGARQVFERWMEWQPEEQA 345 Score = 31.6 bits (70), Expect = 0.83, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 5/116 (4%) Query: 41 AKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIEL----DKKYI 96 AKD E + Y ++EL P + + Y + E L A RA+ K Sbjct: 548 AKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTSIGKCPKN- 606 Query: 97 KGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAI 152 K + + L +F + YE ++ P + + +K+ E I+ RAI Sbjct: 607 KLFKVYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIDRARAI 662 >1HH8-A nrPDB Length = 213 Score = 31.6 bits (70), Expect = 0.73, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%) Query: 33 TQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAI 89 Y K+ A K ++++I + A+ Y R + Y +TE Y A+ D A+ Sbjct: 42 NIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEAL 98 >5O09-1C nrPDB Length = 238 Score = 31.6 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 54/157 (34%), Gaps = 27/157 (17%) Query: 8 RTECAEPPRDEPPAEGTLKRAEELKTQ------------ANDYFKAKDYENAIKFYSQAI 55 R + + + E L RA+EL+ Q A+ Y + + A +FY A+ Sbjct: 43 RQKEGDFRKAESLYREALFRAQELRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELAL 102 Query: 56 ELNPSN--------AIYYGNRSLAYLRTECYGYALGDATRAIE----LDKKYIKGYYRRA 103 +++ N A N ++ + + + A G A+E LD + R A Sbjct: 103 KISAENGLEESDKVATIKNNLAMIFKQLRKFERAEGYYCEALETFQRLDGEQS---ARVA 159 Query: 104 ASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECS 140 + LG + D + + + E Sbjct: 160 SVYNNLGVLYYSHMDVDRAQVMHERALAIRQNLHEGQ 196 >4WRT-C nrPDB Length = 798 Score = 31.6 bits (70), Expect = 0.87, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 47/121 (38%), Gaps = 20/121 (16%) Query: 79 GYALGDATRAIELDKKYIKGYYRRAASNMAL------GKFRAALRDYETV---VKVKPND 129 L R + L K R+ N L GK+ L D++T+ K+KP + Sbjct: 674 TEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGDFKTIEELEKLKPGE 733 Query: 130 KDAKMKYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDE------YSGPKLED 183 K + YQ V ++ A++ D + + + MT+E +S P+ E Sbjct: 734 KANILLYQGKPVKVVKRKRYSALSND-----ISQGIKRQRMTVESMGWALSGWSHPQFEK 788 Query: 184 G 184 G Sbjct: 789 G 789 >5CCB-B nrPDB Length = 497 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 63/175 (36%), Gaps = 20/175 (11%) Query: 79 GYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDA----KM 134 G + AT K ++ G Y L K + L + + KD+ + Sbjct: 234 GGPVRAATACFGFPKSFLSGLY-----EFPLNKVDSLLHGTFSAKMLSSEPKDSALVEES 288 Query: 135 KYQECSKIVKQKAFERAIAGDEHRRSVVDSLDIESMTIEDEYSGPKLEDGKVTITFMKDL 194 K ++ E ++A D +E+++ + E+ GPK K ++++ Sbjct: 289 NGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKGPKERGSKK--DYIQEK 346 Query: 195 MQWYKDQKKLHRKCAYQILVQVKEVLCKLS---------TLVETTLKETEKITVC 240 + ++Q+K H + A + + + L S +L++ + C Sbjct: 347 QRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRPFVVYC 401 >6MFV-A nrPDB Length = 653 Score = 30.4 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 40/100 (40%), Gaps = 7/100 (7%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKK 94 + Y +YE I +Y +A+++ + I + ++Y+ Y L +A E +K Sbjct: 489 GDIYLHMGNYEKGISYYQEALKMAKAYGIKFLEH-ISYMELAKGYYQLKLYEKASEYSEK 547 Query: 95 YIKGY-----YRRAASNMALGKFR-AALRDYETVVKVKPN 128 + YRRA MA G A ++ E K Sbjct: 548 AANYFLMIRNYRRATDAMAYGSVSYIATKNLEKAEKFAKE 587 >2ZAO-A nrPDB Length = 444 Score = 29.7 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 21/33 (63%) Query: 24 TLKRAEELKTQANDYFKAKDYENAIKFYSQAIE 56 L++A +L ++A KA +YE A++ Y A++ Sbjct: 7 NLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQ 39 >3R25-A nrPDB Length = 401 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 22/56 (39%), Gaps = 1/56 (1%) Query: 270 GDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEV-KAKYT 324 G + D+ + + + Y + FH+L HE NQ F EV + K Sbjct: 175 GSYYDQDQYMDNTLTMFKSLREKYGNQFHILHDVHERLFPNQAIQFAKEVEQYKPY 230 >3R6N-A nrPDB Length = 450 Score = 29.3 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 26/68 (38%), Gaps = 1/68 (1%) Query: 14 PPRDEPPAEGTLKRAEEL-KTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAY 72 P P + L++ +EL K + + +N + + ++L P N Y N+ + Sbjct: 227 PCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKPRNPDYRSNKPIIL 286 Query: 73 LRTECYGY 80 Y Sbjct: 287 RALCDYKQ 294 >6CQO-A nrPDB Length = 119 Score = 28.5 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 14/73 (19%), Positives = 28/73 (38%), Gaps = 8/73 (10%) Query: 407 GPDVTKAFLEENQ--LDYIIRSHEVKAEGYEVAHGGRCVTVFSAP--NYCDQMGNKASYI 462 G + T+ N L Y I S + + +TVF+ P N+ + K + + Sbjct: 13 GSEFTEHTSANNNRYLKYSIASQPRRDGQTNWYN----ITVFNEPQINFLTEYVRKGALV 68 Query: 463 HLQGSDLRPQFHQ 475 +++ F + Sbjct: 69 YVEADAANYVFER 81 >3JCM-G nrPDB Length = 899 Score = 28.5 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 18/127 (14%), Positives = 45/127 (35%), Gaps = 1/127 (0%) Query: 35 ANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRS-LAYLRTECYGYALGDATRAIELDK 93 Y + E + + Y L P+ + + + S + + + A R + + Sbjct: 675 GQIYHSMGNIEMSRETYLSGTRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKNP 734 Query: 94 KYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIA 153 + Y + + LG A ++ P++ ++ + K + + ++ I Sbjct: 735 DDVLFYIAKIQMEIRLGNLDQAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIF 794 Query: 154 GDEHRRS 160 D RR+ Sbjct: 795 QDALRRT 801 >5A1Y-X nrPDB Length = 308 Score = 28.1 bits (61), Expect = 8.5, Method: Composition-based stats. Identities = 15/116 (12%), Positives = 37/116 (31%), Gaps = 4/116 (3%) Query: 36 NDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKY 95 N + + A + + + + ++ + + A G A++ D + Sbjct: 190 NLAVGGEKLQEAYYIFQELADKCSPTLLLLNGQAACHSAQGRWETAEGVLQEALDKDSGH 249 Query: 96 IKGYYRRAASNMALGKFRAA----LRDYETVVKVKPNDKDAKMKYQECSKIVKQKA 147 + + LGK L + + P K+ + K + ++ Q A Sbjct: 250 PETLINLIVLSQHLGKPPEVTNRYLSQLKDAHRAHPFIKEYQAKENDFDRLAMQYA 305 >5DSE-A nrPDB Length = 837 Score = 28.1 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 31/85 (36%) Query: 45 ENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAA 104 A+ + +A L+P++ +L + ALG +A++L + A Sbjct: 492 RKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQLQGDDANSLHLLAL 551 Query: 105 SNMALGKFRAALRDYETVVKVKPND 129 A + AL + + P + Sbjct: 552 LLSAQKHYHDALNIIDMALSEYPEN 576 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.133 0.347 Lambda K H 0.267 0.0406 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,290,334 Number of Sequences: 36641 Number of extensions: 709922 Number of successful extensions: 2251 Number of sequences better than 10.0: 85 Number of HSP's better than 10.0 without gapping: 96 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 1906 Number of HSP's gapped (non-prelim): 236 length of query: 499 length of database: 10,336,785 effective HSP length: 101 effective length of query: 398 effective length of database: 6,636,044 effective search space: 2641145512 effective search space used: 2641145512 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.1 bits)