BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P53004 (296 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2H63-A nrPDB 588 e-168 1LC0-A nrPDB 473 e-134 3F4L-A nrPDB 60 1e-09 3I23-A nrPDB 50 1e-06 3EC7-A nrPDB 49 2e-06 3HNP-A nrPDB 48 4e-06 3RC7-A nrPDB 47 1e-05 2GLX-A nrPDB 43 2e-04 3GDO-A nrPDB 42 3e-04 3EZY-A nrPDB 40 8e-04 4KOA-A nrPDB 39 0.003 2O4U-X nrPDB 39 0.003 1EVJ-A nrPDB 38 0.005 4EW6-A nrPDB 38 0.006 3OQB-A nrPDB 35 0.036 4HKT-A nrPDB 33 0.17 6JNK-A nrPDB 31 0.57 3TVI-A nrPDB 30 1.7 4R8G-E nrPDB 30 1.7 5BN5-A nrPDB 29 2.9 3HOX-E nrPDB 28 5.4 3GBX-A nrPDB 28 6.9 3G8M-A nrPDB 27 7.4 3DO5-A nrPDB 27 7.9 5JWG-A nrPDB 27 9.5 >2H63-A nrPDB Length = 292 Score = 588 bits (1516), Expect = e-168, Method: Compositional matrix adjust. Identities = 290/290 (100%), Positives = 290/290 (100%) Query: 7 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ 66 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ Sbjct: 3 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ 62 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV Sbjct: 63 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 122 Query: 127 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLV 186 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLV Sbjct: 123 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLV 182 Query: 187 SATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGV 246 SATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGV Sbjct: 183 SATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGV 242 Query: 247 NKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK 296 NKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK Sbjct: 243 NKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK 292 >1LC0-A nrPDB Length = 294 Score = 473 bits (1216), Expect = e-134, Method: Compositional matrix adjust. Identities = 241/289 (83%), Positives = 265/289 (91%), Gaps = 1/289 (0%) Query: 8 KFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQE 67 KFGVVVVGVGRAGSVR+RDL++P S+AFLNLIGFVSRRELGS+D V+QISLEDAL SQE Sbjct: 7 KFGVVVVGVGRAGSVRLRDLKDPR-SAAFLNLIGFVSRRELGSLDEVRQISLEDALRSQE 65 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVE 127 ++VAYICSESSSHEDYIRQFL AGKHVLVEYPMTLS AAAQELWELA QKG+VLHEEHVE Sbjct: 66 IDVAYICSESSSHEDYIRQFLQAGKHVLVEYPMTLSFAAAQELWELAAQKGRVLHEEHVE 125 Query: 128 LLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVS 187 LLMEEF FL++EV+GK+LLKGSL FTA PLEEERFGFPAFSGISRLTWLVSLFGELSL+S Sbjct: 126 LLMEEFEFLRREVLGKELLKGSLRFTASPLEEERFGFPAFSGISRLTWLVSLFGELSLIS 185 Query: 188 ATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVN 247 ATLEERKEDQYMKMTV LET+ K LSWIEEKGPGLKRNRY++F F SGSLE VP+VGVN Sbjct: 186 ATLEERKEDQYMKMTVQLETQNKGLLSWIEEKGPGLKRNRYVNFQFTSGSLEEVPSVGVN 245 Query: 248 KNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK 296 KNIFLKDQ+IFVQKLL Q S ++LAAEKKRI+HCLGLA +IQK C +K Sbjct: 246 KNIFLKDQDIFVQKLLDQVSAEDLAAEKKRIMHCLGLASDIQKLCHQKK 294 >3F4L-A nrPDB Length = 345 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 43/139 (30%), Positives = 72/139 (51%), Gaps = 9/139 (6%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 L++ L+ +V++ +C+ + SH +Y ++ L AGK+VLVE P T +LA A+EL+ LA+ K Sbjct: 56 DLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSK 115 Query: 118 GKVLHEEHVELLMEEFAFLKKEV----VGKDLLKGSLLFTAGPLEEERFGFP---AFS-- 168 G + F KK + +G+ + S P+ E + G P AF Sbjct: 116 GLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGL 175 Query: 169 GISRLTWLVSLFGELSLVS 187 G+ + ++SLFG V+ Sbjct: 176 GVHTMDQIISLFGRPDHVA 194 >3I23-A nrPDB Length = 349 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 40/64 (62%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 L + L+ E+E+ IC+ + +H D +Q + AGK V+VE P +L A+EL+ L ++K Sbjct: 56 DLNELLTDPEIELITICTPAHTHYDLAKQAILAGKSVIVEKPFCDTLEHAEELFALGQEK 115 Query: 118 GKVL 121 G V+ Sbjct: 116 GVVV 119 >3EC7-A nrPDB Length = 357 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 5/112 (4%) Query: 13 VVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSID-----GVQQISLEDALSSQE 67 +VG+G GS +R L N + + V+ R ++D D ++ ++ Sbjct: 28 IVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDKD 87 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGK 119 VEV I + + +H D LNA K+V E P+ ++ A Q + E ++ GK Sbjct: 88 VEVVIITASNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGK 139 >3HNP-A nrPDB Length = 353 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 38/146 (26%), Positives = 70/146 (47%), Gaps = 17/146 (11%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 L++ L+ +E++V IC+ + +H + ++ + AGK V+VE P ++ A+EL L +K Sbjct: 56 DLDELLNDKEIQVVTICTPAHTHYELAKKVILAGKSVIVEKPFCDTVEHAKELLALGREK 115 Query: 118 GKVLHEEHVELLMEEFAFLKKEV----VGK--------DLLKGSLLFTAGPLEEERFGFP 165 G V+ +F +K+ V +G D + + P EE F Sbjct: 116 GVVVMPYQNRRFDGDFLAVKQVVEQGFLGDIIEIESHIDYFRPGSITHEAPKEEGSF--- 172 Query: 166 AFS-GISRLTWLVSLFGELSLVSATL 190 +S GI + ++SLFG + V+ + Sbjct: 173 -YSLGIHTMDRMISLFGRPNTVTYDI 197 >3RC7-A nrPDB Length = 350 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 8/74 (10%) Query: 63 LSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLH 122 L +V+ Y+ + H ++I + L AGKHVL E P+T A+ L+ +A ++G Sbjct: 85 LERDDVDAVYVPLPAVLHAEWIDRALRAGKHVLAEKPLTTDRPQAERLFAVARERGL--- 141 Query: 123 EEHVELLMEEFAFL 136 LLME F FL Sbjct: 142 -----LLMENFMFL 150 >2GLX-A nrPDB Length = 332 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 37/68 (54%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 S+E+ + +V+ Y+ + + H + + AGKHVL E P+ ++L A+E+ A + Sbjct: 53 SVEELVGDPDVDAVYVSTTNELHREQTLAAIRAGKHVLCEKPLAMTLEDAREMVVAAREA 112 Query: 118 GKVLHEEH 125 G VL H Sbjct: 113 GVVLGTNH 120 >3GDO-A nrPDB Length = 358 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 63/131 (48%), Gaps = 5/131 (3%) Query: 11 VVVVGVGRAGSV---RMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQE 67 V ++G G +GSV + D+ + + S + +R+ + V + LE+ + Sbjct: 8 VGILGYGLSGSVFHGPLLDVLDEYQISKIMTSRTEEVKRDFPDAEVVHE--LEEITNDPA 65 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVE 127 +E+ + + S H ++ + AGKHV++E PMT + + L A++KG +L H Sbjct: 66 IELVIVTTPSGLHYEHTMACIQAGKHVVMEKPMTATAEEGETLKRAADEKGVLLSVYHNR 125 Query: 128 LLMEEFAFLKK 138 +F +KK Sbjct: 126 RWDNDFLTIKK 136 >3EZY-A nrPDB Length = 344 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 7/114 (6%) Query: 13 VVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSR---RELGSIDGVQQISLE--DALSSQE 67 V+G+GR G++ +L+ A L I V RE+ GV++ + + + Sbjct: 7 VIGLGRIGTIHAENLK--MIDDAILYAISDVREDRLREMKEKLGVEKAYKDPHELIEDPN 64 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVL 121 V+ +CS +++H + + A KHV E P++L+LA + E ++ +L Sbjct: 65 VDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVIL 118 >4KOA-A nrPDB Length = 333 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 34/68 (50%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 S++D + +V+ YI + + H + AGKHVL E P+ ++L E+ A + Sbjct: 54 SVDDLVGDPDVDAVYISTTNELHHGQALAAIRAGKHVLCEKPLAMNLNDGCEMVLKACEA 113 Query: 118 GKVLHEEH 125 G VL H Sbjct: 114 GVVLGTNH 121 >2O4U-X nrPDB Length = 334 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 34/66 (51%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 S E+ VEVAY+ ++ H+ + L AGK VL E PM ++ A +E+ A + Sbjct: 57 SYEELAKDPNVEVAYVGTQHPQHKAAVMLCLAAGKAVLCEKPMGVNAAEVREMVTEARSR 116 Query: 118 GKVLHE 123 G L E Sbjct: 117 GLFLME 122 >1EVJ-A nrPDB Length = 352 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 30/55 (54%) Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVL 121 +++ YI +S H ++ + AGKHV+ E PM S+A Q + + A+ K L Sbjct: 69 KIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAANKKL 123 >4EW6-A nrPDB Length = 330 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 13/138 (9%) Query: 11 VVVVGVGRAGSVRMRDLRNPH-PSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQE-- 67 + +VGVG+ +RD P +A L+ SR G+++GV + +A+ E Sbjct: 28 LAIVGVGKI----VRDQHLPSIAKNANFKLVATASRH--GTVEGVNSYTTIEAMLDAEPS 81 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVL----HE 123 ++ +C + + L AGKHV +E P +L+ +L LA ++G L H Sbjct: 82 IDAVSLCMPPQYRYEAAYKALVAGKHVFLEKPPGATLSEVADLEALANKQGASLFASWHS 141 Query: 124 EHVELLMEEFAFLKKEVV 141 + + AFL + Sbjct: 142 RYAPAVEAAKAFLASTTI 159 >3OQB-A nrPDB Length = 383 Score = 35.0 bits (79), Expect = 0.036, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 32/61 (52%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 L+ AL+ + + + + + + + Q +NAGKHV E P+ + A E+ +LA K Sbjct: 74 DLDAALADKNDTMFFDAATTQARPGLLTQAINAGKHVYCEKPIATNFEEALEVVKLANSK 133 Query: 118 G 118 G Sbjct: 134 G 134 >4HKT-A nrPDB Length = 331 Score = 32.7 bits (73), Expect = 0.17, Method: Compositional matrix adjust. Identities = 12/30 (40%), Positives = 18/30 (60%) Query: 73 ICSESSSHEDYIRQFLNAGKHVLVEYPMTL 102 IC+ + +H D I +F AGK + E P+ L Sbjct: 69 ICTPTDTHADLIERFARAGKAIFCEKPIDL 98 >6JNK-A nrPDB Length = 310 Score = 31.2 bits (69), Expect = 0.57, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 28/58 (48%) Query: 64 SSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVL 121 + +E++ +C+ R L AGKHV++E P +L L LA ++G L Sbjct: 58 AERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTL 115 >3TVI-A nrPDB Length = 446 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 95 LVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 +VE P T+S + +EL EL+ VLHEE + Sbjct: 220 IVENPKTISKISYKELRELSYMGATVLHEEAI 251 >4R8G-E nrPDB Length = 335 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 4/80 (5%) Query: 115 EQKGKV-LHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRL 173 +QKG V L +HV + + A V ++ +GS+ F GP R G F+ S L Sbjct: 259 KQKGDVVLQSDHVIETLTKTALSADRVNNININQGSITFAGGP---GRDGIIDFTSGSEL 315 Query: 174 TWLVSLFGELSLVSATLEER 193 + G L++V+ L R Sbjct: 316 LITKAKNGHLAVVAPRLNSR 335 >5BN5-A nrPDB Length = 570 Score = 28.9 bits (63), Expect = 2.9, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 8/57 (14%) Query: 98 YPMTLSLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKE--------VVGKDLL 146 YP L + + WE ++ + L+E+ +E+ E FA LK+E +VG D L Sbjct: 414 YPAINYLISYTKQWEFVKKYFEELYEDVIEIREEFFAILKRESELMDIVSIVGPDAL 470 >3HOX-E nrPDB Length = 215 Score = 27.7 bits (60), Expect = 5.4, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 106 AAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFP 165 A + + E+ + +G + +E VEL +E+F + +G+ K + F A P EE FP Sbjct: 15 AFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRK-MMSFQANPTEESISKFP 73 >3GBX-A nrPDB Length = 420 Score = 27.7 bits (60), Expect = 6.9, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 17/24 (70%), Gaps = 1/24 (4%) Query: 109 ELWELAEQKGKVLHEEHVELLMEE 132 ELW+ EQ+ KV EEH+EL+ E Sbjct: 17 ELWQAMEQE-KVRQEEHIELIASE 39 >3G8M-A nrPDB Length = 417 Score = 27.3 bits (59), Expect = 7.4, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 17/24 (70%), Gaps = 1/24 (4%) Query: 109 ELWELAEQKGKVLHEEHVELLMEE 132 ELW+ EQ+ KV EEH+EL+ E Sbjct: 14 ELWQAMEQE-KVRQEEHIELIASE 36 >3DO5-A nrPDB Length = 327 Score = 27.3 bits (59), Expect = 7.9, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 10/91 (10%) Query: 82 DYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKG-KVLHEEH-------VELLMEEF 133 +YIR+ L GKHV+ L +A L LAE+ G ++++E V+L Sbjct: 99 NYIREALKRGKHVVTSNKGPL-VAEFHGLMSLAERNGVRLMYEATVGGAMPVVKLAKRYL 157 Query: 134 AFLKKEVVGKDLLKGSLLFTAGPLEEERFGF 164 A + E V K + G+ + +EEER + Sbjct: 158 ALCEIESV-KGIFNGTCNYILSRMEEERLPY 187 >5JWG-A nrPDB Length = 703 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 1/76 (1%) Query: 54 VQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWEL 113 +Q + L + L+ ++ + Y +SS Y R A + + LA QE+ Sbjct: 285 LQDVMLREMLADPKINIMYAAKYASSQNGYKRA-QGANWAIRRRSLREIKLAQQQEVLAW 343 Query: 114 AEQKGKVLHEEHVELL 129 A+QKG EE V + Sbjct: 344 AKQKGIATTEEAVRAI 359 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2H63-A nrPDB 454 e-128 1LC0-A nrPDB 419 e-118 3F4L-A nrPDB 177 6e-45 3HNP-A nrPDB 168 2e-42 3GDO-A nrPDB 167 6e-42 3I23-A nrPDB 159 1e-39 3EC7-A nrPDB 135 1e-32 3EZY-A nrPDB 133 9e-32 2GLX-A nrPDB 97 7e-21 3RC7-A nrPDB 91 4e-19 Sequences not found previously or not previously below threshold: 4KOA-A nrPDB 86 1e-17 1EVJ-A nrPDB 82 2e-16 3NT2-A nrPDB 80 2e-15 2O4U-X nrPDB 75 4e-14 4MIE-A nrPDB 72 3e-13 2Q4E-A nrPDB 67 7e-12 4HKT-A nrPDB 67 8e-12 6JNK-A nrPDB 65 4e-11 3EUW-A nrPDB 64 5e-11 1ZH8-A nrPDB 63 1e-10 2IXB-A nrPDB 62 4e-10 3OQB-A nrPDB 59 2e-09 4EW6-A nrPDB 55 4e-08 3OA2-A nrPDB 50 1e-06 5UIA-A nrPDB 49 3e-06 3IP3-A nrPDB 47 8e-06 3BTS-A nrPDB 39 0.004 3WBB-A nrPDB 38 0.005 6DZS-A nrPDB 36 0.019 3KB6-A nrPDB 35 0.043 4KQW-A nrPDB 34 0.079 3E1K-A nrPDB 34 0.079 6JCV-A nrPDB 32 0.36 1XDW-A nrPDB 31 0.75 2QC3-A nrPDB 31 0.79 6EKK-A nrPDB 31 0.82 3DC2-A nrPDB 30 0.84 1E5Q-A nrPDB 30 1.0 1ZIT-A nrPDB 30 1.2 2EKL-A nrPDB 30 1.4 3DZD-A nrPDB 30 1.7 3KEQ-A nrPDB 29 2.8 3ORP-A nrPDB 29 2.9 4V03-A nrPDB 29 3.0 4V8M-AI nrPDB 28 3.2 4WJI-A nrPDB 28 3.6 5AOV-A nrPDB 28 4.9 6C55-A nrPDB 28 5.4 3BA1-A nrPDB 28 5.4 1NP3-A nrPDB 28 6.3 6BII-A nrPDB 27 7.2 4TR8-A nrPDB 27 8.1 3VAZ-P nrPDB 27 8.8 4BBD-A nrPDB 27 9.2 >2H63-A nrPDB Length = 292 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 290/290 (100%), Positives = 290/290 (100%) Query: 7 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ 66 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ Sbjct: 3 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ 62 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV Sbjct: 63 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 122 Query: 127 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLV 186 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLV Sbjct: 123 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLV 182 Query: 187 SATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGV 246 SATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGV Sbjct: 183 SATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGV 242 Query: 247 NKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK 296 NKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK Sbjct: 243 NKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK 292 >1LC0-A nrPDB Length = 294 Score = 419 bits (1076), Expect = e-118, Method: Composition-based stats. Identities = 241/289 (83%), Positives = 265/289 (91%), Gaps = 1/289 (0%) Query: 8 KFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQE 67 KFGVVVVGVGRAGSVR+RDL++P S+AFLNLIGFVSRRELGS+D V+QISLEDAL SQE Sbjct: 7 KFGVVVVGVGRAGSVRLRDLKDPR-SAAFLNLIGFVSRRELGSLDEVRQISLEDALRSQE 65 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVE 127 ++VAYICSESSSHEDYIRQFL AGKHVLVEYPMTLS AAAQELWELA QKG+VLHEEHVE Sbjct: 66 IDVAYICSESSSHEDYIRQFLQAGKHVLVEYPMTLSFAAAQELWELAAQKGRVLHEEHVE 125 Query: 128 LLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELSLVS 187 LLMEEF FL++EV+GK+LLKGSL FTA PLEEERFGFPAFSGISRLTWLVSLFGELSL+S Sbjct: 126 LLMEEFEFLRREVLGKELLKGSLRFTASPLEEERFGFPAFSGISRLTWLVSLFGELSLIS 185 Query: 188 ATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVN 247 ATLEERKEDQYMKMTV LET+ K LSWIEEKGPGLKRNRY++F F SGSLE VP+VGVN Sbjct: 186 ATLEERKEDQYMKMTVQLETQNKGLLSWIEEKGPGLKRNRYVNFQFTSGSLEEVPSVGVN 245 Query: 248 KNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK 296 KNIFLKDQ+IFVQKLL Q S ++LAAEKKRI+HCLGLA +IQK C +K Sbjct: 246 KNIFLKDQDIFVQKLLDQVSAEDLAAEKKRIMHCLGLASDIQKLCHQKK 294 >3F4L-A nrPDB Length = 345 Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 43/142 (30%), Positives = 73/142 (51%), Gaps = 9/142 (6%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQK 117 L++ L+ +V++ +C+ + SH +Y ++ L AGK+VLVE P T +LA A+EL+ LA+ K Sbjct: 56 DLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTLAQAKELFALAKSK 115 Query: 118 GKVLHEEHVELLMEEFAFLKKEV----VGKDLLKGSLLFTAGPLEEERFGFP---AFS-- 168 G + F KK + +G+ + S P+ E + G P AF Sbjct: 116 GLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVAETKPGLPQDGAFYGL 175 Query: 169 GISRLTWLVSLFGELSLVSATL 190 G+ + ++SLFG V+ + Sbjct: 176 GVHTMDQIISLFGRPDHVAYDI 197 >3HNP-A nrPDB Length = 353 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 21/197 (10%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQ----QISLEDALSSQ 66 + +G G++ + + + EL + + L++ L+ + Sbjct: 5 MGFIGFGKSANRYHLPYLKTRNNIKVKTIFVRQINEELAAPYEERGVYFTTDLDELLNDK 64 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 E++V IC+ + +H + ++ + AGK V+VE P ++ A+EL L +KG V+ Sbjct: 65 EIQVVTICTPAHTHYELAKKVILAGKSVIVEKPFCDTVEHAKELLALGREKGVVVMPYQN 124 Query: 127 ELLMEEFAFLKKEV----VGK--------DLLKGSLLFTAGPLEEERFGFPAFS-GISRL 173 +F +K+ V +G D + + P EE F +S GI + Sbjct: 125 RRFDGDFLAVKQVVEQGFLGDIIEIESHIDYFRPGSITHEAPKEEGSF----YSLGIHTM 180 Query: 174 TWLVSLFGELSLVSATL 190 ++SLFG + V+ + Sbjct: 181 DRMISLFGRPNTVTYDI 197 >3GDO-A nrPDB Length = 358 Score = 167 bits (423), Expect = 6e-42, Method: Composition-based stats. Identities = 43/201 (21%), Positives = 84/201 (41%), Gaps = 17/201 (8%) Query: 11 VVVVGVGRAGSV---RMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQE 67 V ++G G +GSV + D+ + + S + +R+ + V + LE+ + Sbjct: 8 VGILGYGLSGSVFHGPLLDVLDEYQISKIMTSRTEEVKRDFPDAEVVHE--LEEITNDPA 65 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVE 127 +E+ + + S H ++ + AGKHV++E PMT + + L A++KG +L H Sbjct: 66 IELVIVTTPSGLHYEHTMACIQAGKHVVMEKPMTATAEEGETLKRAADEKGVLLSVYHNR 125 Query: 128 LLMEEFAFLKKEV------------VGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTW 175 +F +KK + V + + + E G G + Sbjct: 126 RWDNDFLTIKKLISEGSLEDINTYQVSYNRYRPEVQARWREKEGTATGTLYDLGSHIIDQ 185 Query: 176 LVSLFGELSLVSATLEERKED 196 + LFG V+A + ++E+ Sbjct: 186 TLHLFGMPKAVTANVMAQREN 206 >3I23-A nrPDB Length = 349 Score = 159 bits (403), Expect = 1e-39, Method: Composition-based stats. Identities = 40/193 (20%), Positives = 82/193 (42%), Gaps = 13/193 (6%) Query: 11 VVVVGVGRAGS---VRMRDLRNPHPSSAFLNL-IGFVSRRELGSIDGVQQISLEDALSSQ 66 + +G G++ + + +R +L + + L + L+ Sbjct: 5 MGFIGFGKSANRYHLPYVMIRETLEVKTIFDLHVNEKAAAPFKEKGVNFTADLNELLTDP 64 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 E+E+ IC+ + +H D +Q + AGK V+VE P +L A+EL+ L ++KG V+ Sbjct: 65 EIELITICTPAHTHYDLAKQAILAGKSVIVEKPFCDTLEHAEELFALGQEKGVVVMPYQN 124 Query: 127 ELLMEEFAFLKKEV----VGKDLLKGSLLFTAGP---LEEERFGFPAFS--GISRLTWLV 177 ++ +K+ V +G+ + + P E+ +F GI + ++ Sbjct: 125 RRFDGDYLAMKQVVEQGFLGEINEVETHIDYYRPGSITEQGPKENGSFYGLGIHLMDRMI 184 Query: 178 SLFGELSLVSATL 190 +LFG V+ + Sbjct: 185 ALFGRPDQVTYDI 197 >3EC7-A nrPDB Length = 357 Score = 135 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 39/182 (21%), Positives = 76/182 (41%), Gaps = 11/182 (6%) Query: 12 VVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSID-----GVQQISLEDALSSQ 66 +VG+G GS +R L N + + V+ R ++D D ++ + Sbjct: 27 GIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDK 86 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGK-VLHEEH 125 +VEV I + + +H D LNA K+V E P+ ++ A Q + E ++ GK ++ Sbjct: 87 DVEVVIITASNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGF 146 Query: 126 VELLMEEFAFLKKEV----VGKDLLKGSLLFTAGPLEEERFGFPAFSG-ISRLTWLVSLF 180 + + + LK + +G+ L+ + A + E + + I + + L Sbjct: 147 MRRYDKGYVQLKNIIDSGEIGQPLMVHGRHYNASTVPEYKTPQAIYETLIHEIDVMHWLL 206 Query: 181 GE 182 E Sbjct: 207 NE 208 >3EZY-A nrPDB Length = 344 Score = 133 bits (334), Expect = 9e-32, Method: Composition-based stats. Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 11/204 (5%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSR---RELGSIDGVQQISLE--DALSS 65 + V+G+GR G++ +L+ A L I V RE+ GV++ + + + Sbjct: 5 IGVIGLGRIGTIHAENLK--MIDDAILYAISDVREDRLREMKEKLGVEKAYKDPHELIED 62 Query: 66 QEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEH 125 V+ +CS +++H + + A KHV E P++L+LA + E ++ +L Sbjct: 63 PNVDAVLVCSSTNTHSELVIACAKAKKHVFCEKPLSLNLADVDRMIEETKKADVILFTGF 122 Query: 126 VELLMEEFAFLKKEVVGKDLLKGS-LLFTAGPLEEERFGFPAFSGISRLTWLVSLFGELS 184 F LK+ V + K L T+ + SG L + F Sbjct: 123 NRRFDRNFKKLKEAVENGTIGKPHVLRITSRDPAPPPLDYIRVSGGIFLDMTIHDF---D 179 Query: 185 LVSATLEERKEDQYMKMTVCLETE 208 + + E E+ + +V ++ E Sbjct: 180 MARYIMGEEVEEVFADGSVLVDEE 203 >2GLX-A nrPDB Length = 332 Score = 97.4 bits (241), Expect = 7e-21, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 38/76 (50%) Query: 53 GVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWE 112 G S+E+ + +V+ Y+ + + H + + AGKHVL E P+ ++L A+E+ Sbjct: 48 GKSVTSVEELVGDPDVDAVYVSTTNELHREQTLAAIRAGKHVLCEKPLAMTLEDAREMVV 107 Query: 113 LAEQKGKVLHEEHVEL 128 A + G VL H Sbjct: 108 AAREAGVVLGTNHHLR 123 >3RC7-A nrPDB Length = 350 Score = 91.3 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 14/138 (10%) Query: 2 NAEPERKFGVVVVGVGRAG---SVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQIS 58 NA P R V V+G ++ + +A + ++R G Sbjct: 24 NANPIR---VGVIGCADIAWRRALPALEAEPLTEVTAIASRRWDRAKRFTERFGGEPVEG 80 Query: 59 LEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKG 118 L +V+ Y+ + H ++I + L AGKHVL E P+T A+ L+ +A ++G Sbjct: 81 YPALLERDDVDAVYVPLPAVLHAEWIDRALRAGKHVLAEKPLTTDRPQAERLFAVARERG 140 Query: 119 KVLHEEHVELLMEEFAFL 136 LLME F FL Sbjct: 141 L--------LLMENFMFL 150 >4KOA-A nrPDB Length = 333 Score = 86.3 bits (212), Expect = 1e-17, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 51/120 (42%), Gaps = 4/120 (3%) Query: 33 SSAFLNLIGFVSRR--ELGSIDGVQQI--SLEDALSSQEVEVAYICSESSSHEDYIRQFL 88 ++++ + R + +G+ + S++D + +V+ YI + + H + Sbjct: 25 GGEVVSVMSSSAERGEAYAAENGIAKAVTSVDDLVGDPDVDAVYISTTNELHHGQALAAI 84 Query: 89 NAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKG 148 AGKHVL E P+ ++L E+ A + G VL H +++ + + + Sbjct: 85 RAGKHVLCEKPLAMNLNDGCEMVLKACEAGVVLGTNHHLRNAATHRAMREAIAAGRIGRP 144 >1EVJ-A nrPDB Length = 352 Score = 82.4 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 8/124 (6%) Query: 7 RKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRE--LGSIDGVQ------QIS 58 R+FG +VG+G+ ++ S L+ + + + + GV + Sbjct: 1 RRFGYAIVGLGKYALNQILPGFAGCQHSRIEALVDGNAEKAKIVAAEYGVDPRKIYDYSN 60 Query: 59 LEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKG 118 + +++ YI +S H ++ + AGKHV+ E PM S+A Q + + A+ Sbjct: 61 FDKIAKDPKIDAVYIILPNSLHAEFAIRAFKAGKHVMCEKPMATSVADCQRMIDAAKAAN 120 Query: 119 KVLH 122 K L Sbjct: 121 KKLM 124 >3NT2-A nrPDB Length = 344 Score = 79.7 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 56/146 (38%), Gaps = 10/146 (6%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQ-----QISLEDALSS 65 + V+G G G + + N + + + ++ Q + + L+ Sbjct: 5 IGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKVVEQYQLNATVYPNDDSLLAD 64 Query: 66 QEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGK-VLHEE 124 + V+ + S +HE + + + A K+V E P+ + + E + GK ++ Sbjct: 65 ENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATTAEGCMRIVEEEIKVGKRLVQVG 124 Query: 125 HVELLMEEFAFLKKE----VVGKDLL 146 + + LK+ V+G+ L+ Sbjct: 125 FMRRYDSGYVQLKEALDNHVIGEPLM 150 >2O4U-X nrPDB Length = 334 Score = 75.1 bits (183), Expect = 4e-14, Method: Composition-based stats. Identities = 32/135 (23%), Positives = 50/135 (37%), Gaps = 7/135 (5%) Query: 12 VVVGVGRAGSVRMRDL----RNPHPSSAFLNLIGFVSRRELGSIDGVQQIS--LEDALSS 65 +V VG S L R+ H A +E + + E+ Sbjct: 6 GIVSVGLISSDFTAVLQTLPRSEHQVVAV-AARDLSRAKEFAQKHDIPKAYGSYEELAKD 64 Query: 66 QEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEH 125 VEVAY+ ++ H+ + L AGK VL E PM ++ A +E+ A +G L E Sbjct: 65 PNVEVAYVGTQHPQHKAAVMLCLAAGKAVLCEKPMGVNAAEVREMVTEARSRGLFLMEAI 124 Query: 126 VELLMEEFAFLKKEV 140 L+ + Sbjct: 125 WTRFFPASEALRSVL 139 >4MIE-A nrPDB Length = 351 Score = 72.0 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 53/137 (38%), Gaps = 8/137 (5%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGS-----IDGVQQISLEDALSS 65 V V+G G G + L N + + + + ++ L Sbjct: 17 VGVIGTGAMGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAKVYPDDTSLLQD 76 Query: 66 QEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELW--ELAEQKGKVLHE 123 +++ ++ S +HE + + L+ K + E P+ +L A+ + EL + K KV+ Sbjct: 77 PDIDAVFVVSFGGAHEATVLKALDTDKFIFTEKPLATTLEGAKRIVDKELTKSK-KVIQV 135 Query: 124 EHVELLMEEFAFLKKEV 140 + + LK+++ Sbjct: 136 GFMRRYDQGIRALKEKL 152 >2Q4E-A nrPDB Length = 362 Score = 67.4 bits (163), Expect = 7e-12, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 62/162 (38%), Gaps = 13/162 (8%) Query: 6 ERKFGVVVVGVGRAGSVRMRDL-RNPHPSSAFLNLIGFVSRRELGSIDGVQQI-----SL 59 E + + V+G R + P+ + + + + + + + S Sbjct: 4 ETQIRIGVMGCADIARKVSRAIHLAPNATISGVASRSLEKAKAFATANNYPESTKIHGSY 63 Query: 60 EDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGK 119 E L E++ Y+ +S H ++ + GKH+L+E P+ +++ ++ + E G Sbjct: 64 ESLLEDPEIDALYVPLPTSLHVEWAIKAAEKGKHILLEKPVAMNVTEFDKIVDACEANGV 123 Query: 120 VLHE----EHVEL--LMEEFAFLKKEVVGKDLLKGSLLFTAG 155 + + H L++EF E G+ S AG Sbjct: 124 QIMDGTMWVHNPRTALLKEFLS-DSERFGQLKTVQSCFSFAG 164 >4HKT-A nrPDB Length = 331 Score = 67.4 bits (163), Expect = 8e-12, Method: Composition-based stats. Identities = 23/130 (17%), Positives = 51/130 (39%), Gaps = 1/130 (0%) Query: 12 VVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSID-GVQQISLEDALSSQEVEV 70 ++G GR G V + + + F + E + G + +++ ++ +++ Sbjct: 7 GLLGAGRIGKVHAKAVSGNADARLVAVADAFPAAAEAIAGAYGCEVRTIDAIEAAADIDA 66 Query: 71 AYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVELLM 130 IC+ + +H D I +F AGK + E P+ L + ++ L Sbjct: 67 VVICTPTDTHADLIERFARAGKAIFCEKPIDLDAERVRACLKVVSDTKAKLMVGFNRRFD 126 Query: 131 EEFAFLKKEV 140 F ++K + Sbjct: 127 PHFMAVRKAI 136 >6JNK-A nrPDB Length = 310 Score = 65.1 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 47/125 (37%), Gaps = 6/125 (4%) Query: 5 PERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALS 64 P + + VVG+G+ RD P + + + R L L+ Sbjct: 2 PSDQVSLGVVGIGKI----ARDQHLPAIDAEPGFKLTACASRHAEVTGVRNYRDLRALLA 57 Query: 65 -SQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVL-H 122 +E++ +C+ R L AGKHV++E P +L L LA ++G L Sbjct: 58 AERELDAVSLCAPPQVRYAQARAALEAGKHVMLEKPPGATLGEVAVLEALARERGLTLFA 117 Query: 123 EEHVE 127 H Sbjct: 118 TWHSR 122 >3EUW-A nrPDB Length = 344 Score = 64.3 bits (155), Expect = 5e-11, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 51/137 (37%), Gaps = 2/137 (1%) Query: 11 VVVVGVGRAGSVRMRDLR-NPHPSSAFLNLIGFVSRRELGSIDGVQQ-ISLEDALSSQEV 68 + + G GR G V ++ NP + + L +G + S ++ + ++ Sbjct: 7 IALFGAGRIGHVHAANIAANPDLELVVIADPFIEGAQRLAEANGAEAVASPDEVFARDDI 66 Query: 69 EVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVEL 128 + I S +S+H D I + + G L E P+ L + + E + Sbjct: 67 DGIVIGSPTSTHVDLITRAVERGIPALCEKPIDLDIEMVRACKEKIGDGASKVMLGFNRR 126 Query: 129 LMEEFAFLKKEVVGKDL 145 FA + V +++ Sbjct: 127 FDPSFAAINARVANQEI 143 >1ZH8-A nrPDB Length = 340 Score = 63.2 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 30/142 (21%), Positives = 58/142 (40%), Gaps = 5/142 (3%) Query: 4 EPERKFGVVVVGVGRAG-SVRMRDLRNPHPSSAF--LNLIGFVSRRELGSIDGVQQI--S 58 +P RK + +VG G A + + L+N + E + G + S Sbjct: 14 KPLRKIRLGIVGCGIAARELHLPALKNLSHLFEITAVTSRTRSHAEEFAKMVGNPAVFDS 73 Query: 59 LEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKG 118 E+ L S V+ + + +I + L G HV+ E P++ + +++ EL+E+ Sbjct: 74 YEELLESGLVDAVDLTLPVELNLPFIEKALRKGVHVICEKPISTDVETGKKVVELSEKSE 133 Query: 119 KVLHEEHVELLMEEFAFLKKEV 140 K ++ + F K+ V Sbjct: 134 KTVYIAENFRHVPAFWKAKELV 155 >2IXB-A nrPDB Length = 444 Score = 61.6 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 24/155 (15%), Positives = 58/155 (37%), Gaps = 16/155 (10%) Query: 7 RKFGVVVVGVGRAGSVRMRDL--RNPHPSSAFLNLIGFVSRREL----------GSIDGV 54 +K + + VG G + ++ R+ AF + ++ R + G Sbjct: 19 KKVRIAFIAVGLRGQTHVENMARRDDVEIVAFADPDPYMVGRAQEILKKNGKKPAKVFGN 78 Query: 55 QQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELA 114 ++ L + ++ ++ S H ++ + AGK V +E ++L + +++ Sbjct: 79 GNDDYKNMLKDKNIDAVFVSSPWEWHHEHGVAAMKAGKIVGMEVSGAITLEECWDYVKVS 138 Query: 115 EQKGKVLHEEHVELLMEEFAFL----KKEVVGKDL 145 EQ G L + + +K + G+ + Sbjct: 139 EQTGVPLMALENVCYRRDVMAILNMVRKGMFGELV 173 >3OQB-A nrPDB Length = 383 Score = 59.3 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 61/159 (38%), Gaps = 10/159 (6%) Query: 13 VVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQ--ISLEDALSSQEVEV 70 +V + G VR+++ + L L + + L+ AL+ + + Sbjct: 28 IVAIRDQGGVRLKN-GDRIMPDPILVGRSAEKVEALAKRFNIARWTTDLDAALADKNDTM 86 Query: 71 AYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVELLM 130 + + + + + Q +NAGKHV E P+ + A E+ +LA KG +L + Sbjct: 87 FFDAATTQARPGLLTQAINAGKHVYCEKPIATNFEEALEVVKLANSKGVKHGTVQDKLFL 146 Query: 131 EEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSG 169 LKK L+ S F FG+ F G Sbjct: 147 PG---LKKIA----FLRDSGFFGRILSVRGEFGYWVFEG 178 >4EW6-A nrPDB Length = 330 Score = 55.1 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 35/201 (17%), Positives = 72/201 (35%), Gaps = 22/201 (10%) Query: 11 VVVVGVGRAGSVRMRDLRNPH--PSSAFLNLIGFVSRRELGSIDGVQQISLEDALSS--Q 66 + +VGVG+ +R+ H + N + G+++GV + +A+ Sbjct: 28 LAIVGVGKI-------VRDQHLPSIAKNANFKLVATASRHGTVEGVNSYTTIEAMLDAEP 80 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 ++ +C + + L AGKHV +E P +L+ +L LA ++G L Sbjct: 81 SIDAVSLCMPPQYRYEAAYKALVAGKHVFLEKPPGATLSEVADLEALANKQGASLFASWH 140 Query: 127 ELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERF---------GFPAFS-GISRLTWL 176 K + +K + + G F GI+ L+ + Sbjct: 141 SRYAPAVEAAK-AFLASTTIKSVHVIWKEDVRHWHPNQDWIWQAGGLGVFDPGINALSIV 199 Query: 177 VSLFGELSLVSATLEERKEDQ 197 + ++ + E E++ Sbjct: 200 THILPRPVFITGAVLEFPENR 220 >3OA2-A nrPDB Length = 318 Score = 49.7 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 33/202 (16%), Positives = 66/202 (32%), Gaps = 25/202 (12%) Query: 17 GRAGSVRMRDLRNP-------HPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQ--- 66 G MR +++ + + + +I +S + + + L Sbjct: 13 GYIAPRHMRAIKDTGNCLVSAYDINDSVGIIDSISPQSEFFTEFEFFLDHASNLKRDSAT 72 Query: 67 EVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 ++ ICS + H +I L G V+ E P+ + +L + + K L+ Sbjct: 73 ALDYVSICSPNYLHYPHIAAGLRLGCDVICEKPLVPTPEMLDQLAVIERETDKRLYNILQ 132 Query: 127 ELLMEEFAFLKKEVVGK----DLLKGSLLFTAGPL---------EEERFGFPAFSGISRL 173 + LK +V + T+ + FG G+ Sbjct: 133 LRHHQAIIALKDKVAREKSPHKYEVDLTYITSRGNWYLKSWKGDPRKSFGVATNIGVHFY 192 Query: 174 TWLVSLFGEL--SLVSATLEER 193 L +FG+L ++V T E + Sbjct: 193 DMLHFIFGKLQRNVVHFTSEYK 214 >5UIA-A nrPDB Length = 345 Score = 48.5 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 26/191 (13%), Positives = 58/191 (30%), Gaps = 16/191 (8%) Query: 13 VVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRE--LGSIDGVQ--QISLEDALSSQEV 68 ++G G +M ++ + + +R +G G++ + Sbjct: 10 LIGCGFFAVNQMHAWKD-VKGAGIAAICDRDPKRLKLVGDQFGIERRYGDAAALFADGGF 68 Query: 69 EVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVLHEEHVEL 128 + I + SH + + + P SL+ A+ + E L Sbjct: 69 DFVDIATTVQSHRALVEMAAAHKVPAICQKPFAKSLSDAKAMVRTCENADIPLMVHENFR 128 Query: 129 LMEEFAFLKKEV---------VGKDLLKGSL-LFTAGP-LEEERFGFPAFSGISRLTWLV 177 +K + G+ + +F+ P L E GI L Sbjct: 129 WQTPIQAVKAVLESGAIGEPFWGRFSFRSGFDVFSGQPYLAEGERFIIEDLGIHTLDIAR 188 Query: 178 SLFGELSLVSA 188 + G+++ ++A Sbjct: 189 FILGDVATLTA 199 >3IP3-A nrPDB Length = 337 Score = 47.4 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 50/153 (32%), Gaps = 13/153 (8%) Query: 54 VQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWEL 113 + + + L ++ ++ I + S + + + L H VE P+ + +++ + Sbjct: 54 KKYNNWWEMLEKEKPDILVINTVFSLNGKILLEALERKIHAFVEKPIATTFEDLEKIRSV 113 Query: 114 AEQ--KGKVLHEEHVELLMEEFAFLKKEV----VGKDLLKGSLLFT---AGP----LEEE 160 ++ F KK V VG+ L + P E Sbjct: 114 YQKVRNEVFFTAMFGIRYRPHFLTAKKLVSEGAVGEIRLVNTQKSYKLGQRPDFYKKRET 173 Query: 161 RFGFPAFSGISRLTWLVSLFGELSLVSATLEER 193 G + GI + W+ + G+ L R Sbjct: 174 YGGTIPWVGIHAIDWIHWITGKKFLSVYATHSR 206 >3BTS-A nrPDB Length = 438 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 55/140 (39%), Gaps = 22/140 (15%) Query: 59 LEDALSSQEVEVAYICSESSSHEDYIRQFLNAGK------HVLVEYPMTLSLAAAQELWE 112 LE SS +++ I + +SH + + L K ++ VE+ + SL A+ +++ Sbjct: 81 LESFASSSTIDMIVIAIQVASHYEVVMPLLEFSKNNPNLKYLFVEWALACSLDQAESIYK 140 Query: 113 LAEQKGK-VLHEEHVELLMEEFAFLKKEVVGKDLL----------KGSLLFTAGPLEEER 161 A ++G + + KE++ + + G P++ + Sbjct: 141 AAAERGVQTIISLQGRK--SPYILRAKELISQGYIGDINSIEIAGNGGWYGYERPVKSPK 198 Query: 162 FGFPAFSGISRLTWLVSLFG 181 + + +G+ + + FG Sbjct: 199 YIYEIGNGV---DLVTTTFG 215 >3WBB-A nrPDB Length = 305 Score = 38.1 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 11/116 (9%) Query: 8 KFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRREL----GSIDGVQQISLEDAL 63 K V VVG G G R ++ + L+G V R+ L + GV+ ++ D Sbjct: 9 KLRVAVVGYGNVG----RYALEAVQAAPDMELVGVVRRKVLAATPPELTGVRVVT--DIS 62 Query: 64 SSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAA-QELWELAEQKG 118 + V+ A +C + S +Y L G H + Y + LA + L +A + G Sbjct: 63 QLEGVQGALLCVPTRSVPEYAEAMLRRGIHTVDSYDIHGDLADLRRRLDPVAREHG 118 >6DZS-A nrPDB Length = 441 Score = 36.2 bits (82), Expect = 0.019, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 49/125 (39%), Gaps = 10/125 (8%) Query: 6 ERKFGVVVVGVGRAGSVRMRDLRNPHPSSAF-----LNLIGFVSRRELGSIDGVQQI--- 57 ++ GV V+G+G GS +R + A L L G RR ++ Sbjct: 6 QKPIGVAVLGLGNVGSEVVRIIDESATDLAARIGAPLQLRGIGVRRVSADRGVPVELLTD 65 Query: 58 SLEDALSSQEVEVAY-ICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQ 116 ++E+ +S +V++ + I L GK V+ +S++ EL + AE Sbjct: 66 NIEELVSRDDVDIVVELMGPVEPARKAILTALEQGKSVVTANKALMSVSTG-ELAQAAEA 124 Query: 117 KGKVL 121 L Sbjct: 125 AHVDL 129 >3KB6-A nrPDB Length = 334 Score = 35.0 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 49/137 (35%), Gaps = 6/137 (4%) Query: 8 KFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQE 67 + + V+G GR GS + + L V +RE G SL++ L + Sbjct: 141 RLTLGVIGTGRIGS----RVAMYGLAFGMKVLCYDVVKREDLKEKGCVYTSLDELLKESD 196 Query: 68 VEVAYICSESSSHEDYIRQFLNAGKH-VLVEYPMTLSLAAAQELWELAEQKGKVLHEEHV 126 V ++ +H + ++ K V + + L+ A Q+GK Sbjct: 197 VISLHVPYTKETHHMINEERISLMKDGVYLINTARGKVVDTDALYR-AYQRGKFSGLGLD 255 Query: 127 ELLMEEFAFLKKEVVGK 143 EE LKK GK Sbjct: 256 VFEDEEILILKKYTEGK 272 >4KQW-A nrPDB Length = 350 Score = 33.9 bits (76), Expect = 0.079, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 31/83 (37%), Gaps = 3/83 (3%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEV 70 V ++G G G +L + L S + G++ ++ A +V + Sbjct: 30 VGIIGYGSQGHAHALNLMDSGVDVRV-GLREGSSSWKTAEEAGLKVTDMDTAAEEADVIM 88 Query: 71 AYICSE--SSSHEDYIRQFLNAG 91 + E ++++I L AG Sbjct: 89 VLVPDEIQPKVYQEHIAAHLKAG 111 >3E1K-A nrPDB Length = 465 Score = 33.9 bits (76), Expect = 0.079, Method: Composition-based stats. Identities = 18/133 (13%), Positives = 55/133 (41%), Gaps = 16/133 (12%) Query: 58 SLEDALSSQEVEVAYICSESSSHEDYIRQFLNAG------KHVLVEYPMTLSLAAAQELW 111 SLE +++++ + + H + ++ L +++ VE+ + S+ A+EL+ Sbjct: 77 SLESFAQYKDIDMIVVSVKVPEHYEVVKNILEHSSQNLNLRYLYVEWALAASVQQAEELY 136 Query: 112 ELAEQKGKVLHEEHVELLMEEFAFLKKEVVGKDLL----------KGSLLFTAGPLEEER 161 +++Q+ + ++ + KE++ + + G P+ Sbjct: 137 SISQQRANLQTIICLQGRKSPYIVRAKELISEGCIGDINSIEISGNGGWYGYERPMRSPE 196 Query: 162 FGFPAFSGISRLT 174 + + SG++ ++ Sbjct: 197 YLYDIESGVNLIS 209 >6JCV-A nrPDB Length = 333 Score = 32.0 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 3/96 (3%) Query: 2 NAEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLED 61 N +P + + V+G G G V+ +R + N+ EL +G + +++ Sbjct: 9 NLDPLKGKTIGVIGYGNQGRVQATIMRENGLNVIVGNVKD--KYYELAKKEGFEVYEIDE 66 Query: 62 ALSSQEVEVAYICSESSSH-EDYIRQFLNAGKHVLV 96 A+ +V + I E + + GK V Sbjct: 67 AVRRSDVALLLIPDEVMKEVYEKKIAPVLQGKKEFV 102 >1XDW-A nrPDB Length = 331 Score = 30.8 bits (68), Expect = 0.75, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 51/152 (33%), Gaps = 14/152 (9%) Query: 1 MNAEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLE 60 M ++ R V VVG+GR G + +IG G D Q+SL+ Sbjct: 139 MFSKEVRNCTVGVVGLGRIG-----RVAAQIFHGMGATVIGEDVFEIKGIEDYCTQVSLD 193 Query: 61 DALSSQEVEVAYICSESSSHEDYIRQFLNAGKH----VLVEYPMTLSLAAAQELWELAEQ 116 + L ++ + + R FL K V + A E E + Sbjct: 194 EVLEKSDIITIHAPYIKENGAVVTRDFLKKMKDGAILVNCARGQLVDTEAVIEAVESGK- 252 Query: 117 KGKVLHEEHVELLMEEFAFLKKEVVGKDLLKG 148 L ++L E + K++ G+ L Sbjct: 253 ----LGGYGCDVLDGEASVFGKDLEGQKLENP 280 >2QC3-A nrPDB Length = 303 Score = 30.8 bits (68), Expect = 0.79, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 20/40 (50%) Query: 57 ISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLV 96 S E+ + + + + +H++ R+ + AGK V+V Sbjct: 49 ASTEEITDTAVAQPLIVAATLLAHQELARRCVLAGKDVIV 88 >6EKK-A nrPDB Length = 393 Score = 30.8 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 47/101 (46%), Gaps = 16/101 (15%) Query: 158 EEERFGFPAFSG--------ISRLTWLVSLFGELSLVSATLEERKEDQYMKMTVCLETEK 209 ++RFGF S +S L W + L++++ +R+E+Q+ ++ LET Sbjct: 79 SKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNEL---LETLH 135 Query: 210 KSPLSWIEEKGPGLKRNRYLSFHFKSGSLENVPNVGVNKNI 250 K P+ PG+ + + +F +P++ N+N+ Sbjct: 136 KLPIP-----DPGVSVHLSVHSYFTVPDTRELPSIPENRNL 171 >3DC2-A nrPDB Length = 529 Score = 30.4 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEV 70 V VVG+GR G + + + A++ + G++ +SL+D L+ + Sbjct: 145 VGVVGLGRIGQLVAQRIA---AFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFIS 201 Query: 71 AYICSESSS 79 ++ + Sbjct: 202 VHLPKTPET 210 >1E5Q-A nrPDB Length = 450 Score = 30.4 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 47/123 (38%), Gaps = 15/123 (12%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQIS------LEDALS 64 V+++G G + D+ + S ++L + GVQ + +DA Sbjct: 6 VLMLGSGFV-TRPTLDVLTDSGIKVTVACRTLESAKKLSA--GVQHSTPISLDVNDDAAL 62 Query: 65 SQEV---EVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKVL 121 EV ++ + H I+ + KHV+ ++ ++ EL + A+ G + Sbjct: 63 DAEVAKHDLVISLIPYTFHATVIKSAIRQKKHVVTTSYVSPAM---MELDQAAKDAGITV 119 Query: 122 HEE 124 E Sbjct: 120 MNE 122 >1ZIT-A nrPDB Length = 121 Score = 30.0 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 9/57 (15%), Positives = 18/57 (31%), Gaps = 3/57 (5%) Query: 48 LGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSL 104 + DGV I + + I D + + G + +E P ++ Sbjct: 55 MPDGDGVNFIDF---IKENSPDSVVIVITGHGSVDTAVKAIKKGAYEFLEKPFSVER 108 >2EKL-A nrPDB Length = 313 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 29/69 (42%), Gaps = 3/69 (4%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEV 70 + +VG GR G+ ++ + N I + RE + +SLE+ L + +V Sbjct: 145 IGIVGFGRIGT-KVGIIANAMGMKVLAYDILDI--REKAEKINAKAVSLEELLKNSDVIS 201 Query: 71 AYICSESSS 79 ++ + Sbjct: 202 LHVTVSKDA 210 >3DZD-A nrPDB Length = 368 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 9/57 (15%), Positives = 18/57 (31%), Gaps = 3/57 (5%) Query: 48 LGSIDGVQQISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSL 104 + DGV I + + I D + + G + +E P ++ Sbjct: 54 MPDGDGVNFIDF---IKENSPDSVVIVITGHGSVDTAVKAIKKGAYEFLEKPFSVER 107 >3KEQ-A nrPDB Length = 212 Score = 28.9 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 6/101 (5%) Query: 11 VVVVGVGRAGSV----RMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQIS-LEDALSS 65 V++VG G G R D S AF + + V IS + D L Sbjct: 87 VMLVGCGNIGRALLHYRFHDRNKMQISMAFDLDSNDLVGKTTEDGIPVYGISTINDHLID 146 Query: 66 QEVEVAYICSESSSHEDYIRQFLNAG-KHVLVEYPMTLSLA 105 ++E A + S+ ++ + AG K +L P+ L+L Sbjct: 147 SDIETAILTVPSTEAQEVADILVKAGIKGILSFSPVHLTLP 187 >3ORP-A nrPDB Length = 311 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 23/67 (34%) Query: 13 VVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEVAY 72 ++G G V + H A L ++R + ++ AL+ + Y Sbjct: 19 ILGFGGMSEVHLARDLRDHRDVAVKVLRADLARDPSFYLRFRREAQNAAALNHPAIVAVY 78 Query: 73 ICSESSS 79 E+ + Sbjct: 79 DTGEAET 85 >4V03-A nrPDB Length = 257 Score = 28.9 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 31/77 (40%), Gaps = 2/77 (2%) Query: 45 RRELGSIDGVQQ--ISLEDALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTL 102 +R + +++ ++E+ +S + + S + + + A K ++V P Sbjct: 90 QRANKDVIDIEKWNKTVEEIKNSGNYDYILVDSPAGIEKGFQIAVSPADKALIVVNPEVS 149 Query: 103 SLAAAQELWELAEQKGK 119 S+ A + L E K Sbjct: 150 SIRDADRVIGLLESMDK 166 >4V8M-AI nrPDB Length = 152 Score = 28.5 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 33/85 (38%), Gaps = 6/85 (7%) Query: 83 YIRQFLNAGKHVLV-EYPMTLSLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVV 141 +++ A K+V E P + +++ E G V+ + +K E++ Sbjct: 63 LLKRLREAKKNVKAGEKPKAVK-THLRDVVITPEMVGSVVGIYNGRQF--NAVEIKGEMI 119 Query: 142 GKDLLKGSLLFTAGPLEEERFGFPA 166 G L G T P+ R GF A Sbjct: 120 GHYL--GEFSLTYKPVAHGRPGFGA 142 >4WJI-A nrPDB Length = 293 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 11 VVVVGVGRAGSVRMRDLRN-PHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVE 69 + ++G+G GS RD+R + + + + G + + +L A + + + Sbjct: 7 IALIGIGLIGSSIARDIREKQLAGTIVVTTRSEATLKRAGELGLGDRYTLSAAEAVEGAD 66 Query: 70 VAYICSESSS 79 + + + Sbjct: 67 LVVVSVPVGA 76 >5AOV-A nrPDB Length = 336 Score = 28.1 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 12/72 (16%), Positives = 25/72 (34%), Gaps = 5/72 (6%) Query: 11 VVVVGVGRAGSVRMRDLRN-PHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVE 69 + +VG GR G R + + + +ELG+ + LE+ L + Sbjct: 153 IGIVGFGRIGQAIARRAKGFNMRILYYSRTRKSQAEKELGA----EYRPLEEVLKESDFV 208 Query: 70 VAYICSESSSHE 81 + + + Sbjct: 209 ILAVPLTKETMY 220 >6C55-A nrPDB Length = 340 Score = 28.1 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 34/99 (34%), Gaps = 12/99 (12%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRREL--GSIDGVQQISLEDALSSQEV 68 + VVG G G ++L++ +IG R DG + +A+ ++ Sbjct: 20 IAVVGYGSQGHAHAQNLKDNGYDV----VIGIRPGRSFDKAKEDGFDVFPVAEAV--KQA 73 Query: 69 EVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAA 107 +V + D + + +E L+ A Sbjct: 74 DVIMVLLPDEIQGDVYKNEIEPN----LEKHNALAFAHG 108 >3BA1-A nrPDB Length = 333 Score = 28.1 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 31/71 (43%), Gaps = 7/71 (9%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEV 70 V ++G+GR G L + AF I + SR + + + S+ + S+ ++ V Sbjct: 167 VGIIGLGRIG------LAVAERAEAFDCPISYFSRSKKPNTNYTYYGSVVELASNSDILV 220 Query: 71 AYIC-SESSSH 80 + ++H Sbjct: 221 VACPLTPETTH 231 >1NP3-A nrPDB Length = 338 Score = 27.7 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 13/97 (13%), Positives = 33/97 (34%), Gaps = 7/97 (7%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEV 70 V ++G G G +L++ L + G++ ++ A++ +V Sbjct: 19 VAIIGYGSQGHAHACNLKDSGVDVTV-GLRSGSATVAKAEAHGLKVADVKTAVA--AADV 75 Query: 71 AYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAA 107 I + ++ + ++ TL+ A Sbjct: 76 VMILTPDEFQGRLYKEEIEPN----LKKGATLAFAHG 108 >6BII-A nrPDB Length = 333 Score = 27.3 bits (59), Expect = 7.2, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 23/70 (32%), Gaps = 3/70 (4%) Query: 11 VVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLEDALSSQEVEV 70 + +VG GR G + + L + E G + LE+ L + V Sbjct: 153 IGIVGFGRIGQAIAKRAKG--FGMRILYT-ARSRKPEAEKELGAEFKPLEELLRESDFVV 209 Query: 71 AYICSESSSH 80 + ++ Sbjct: 210 LAVPLTKETY 219 >4TR8-A nrPDB Length = 383 Score = 27.3 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 2/51 (3%) Query: 99 PMTLSLAAAQELWELAEQKGKVLHEEHVELLMEEFAFLKKEVVGK--DLLK 147 P L A+ L E + G VL + H+ EF F K V GK D + Sbjct: 213 PRKGILELARLLTEQDGEVGIVLGQHHIRATTGEFTFTSKLVDGKFPDYER 263 >3VAZ-P nrPDB Length = 344 Score = 27.3 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 39/123 (31%), Gaps = 29/123 (23%) Query: 11 VVVVGVGRAGSVRMRDLR----------NPHPSSAFLNLI---GFVSRRELGSIDGVQ-- 55 V + G GR G + R ++ N L + + R G ++ V Sbjct: 13 VAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHLLKYDTMQGRFTGEVEVVDGG 72 Query: 56 ------------QISLEDA-LSSQEVEVAYICSESSSHEDYIRQFLNAG-KHVLVEYPMT 101 + ++V C+ + +D + + AG K VL+ P T Sbjct: 73 FRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTDKDKAQAHIEAGAKKVLISAPAT 132 Query: 102 LSL 104 L Sbjct: 133 GDL 135 >4BBD-A nrPDB Length = 125 Score = 27.3 bits (59), Expect = 9.2, Method: Composition-based stats. Identities = 13/105 (12%), Positives = 34/105 (32%), Gaps = 19/105 (18%) Query: 59 LEDALSSQEVEVAY----ICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELA 114 L++ + +V + DY+ Q +N ++ A+ + ++ Sbjct: 30 LDELVDDGDVSTLIKNMRMTLSDGPLLDYLNQPVN-------------NIEDAKRMIAIS 76 Query: 115 EQKGKVLHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEE 159 + + + E E F L + + + ++ G E Sbjct: 77 AKVARDIGERSEIRWEESFTILFRMI--ETYFDDLMIDLYGEKLE 119 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.134 0.349 Lambda K H 0.267 0.0409 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,660,361 Number of Sequences: 36641 Number of extensions: 413821 Number of successful extensions: 1239 Number of sequences better than 10.0: 60 Number of HSP's better than 10.0 without gapping: 55 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 1162 Number of HSP's gapped (non-prelim): 91 length of query: 296 length of database: 10,336,785 effective HSP length: 96 effective length of query: 200 effective length of database: 6,819,249 effective search space: 1363849800 effective search space used: 1363849800 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.3 bits)