BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P52888 (689 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2O36-A nrPDB 1397 0.0 4FXY-P nrPDB 903 0.0 5LV0-A nrPDB 901 0.0 4KA7-A nrPDB 261 1e-69 4PUT-A nrPDB 256 2e-68 5L43-A nrPDB 229 4e-60 1Y79-1 nrPDB 198 5e-51 5XM3-A nrPDB 33 0.59 5TQV-A nrPDB 31 1.9 1AVC-A nrPDB 30 3.0 4C9I-A nrPDB 29 8.7 5E3X-A nrPDB 29 8.8 >2O36-A nrPDB Length = 674 Score = 1397 bits (3615), Expect = 0.0, Method: Compositional matrix adjust. Identities = 670/674 (99%), Positives = 670/674 (99%) Query: 16 SPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTY 75 SPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTY Sbjct: 1 SPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTY 60 Query: 76 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR 135 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR Sbjct: 61 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR 120 Query: 136 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQE 195 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQE Sbjct: 121 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQE 180 Query: 196 LGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAI 255 LGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFN RCKEEN AI Sbjct: 181 LGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNSRCKEENSAI 240 Query: 256 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE 315 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE Sbjct: 241 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE 300 Query: 316 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQE 375 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQE Sbjct: 301 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQE 360 Query: 376 LLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL 435 LLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL Sbjct: 361 LLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL 420 Query: 436 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTH 495 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEV TYFHEFGHVMHQLCSQAEFAMFSGTH Sbjct: 421 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVRTYFHEFGHVMHQLCSQAEFAMFSGTH 480 Query: 496 VERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQI 555 VE DFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQI Sbjct: 481 VETDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQI 540 Query: 556 VLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS 615 VLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS Sbjct: 541 VLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS 600 Query: 616 EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK 675 EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK Sbjct: 601 EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK 660 Query: 676 GLQVGGCEPEPQVC 689 GLQVGGCEPEPQVC Sbjct: 661 GLQVGGCEPEPQVC 674 >4FXY-P nrPDB Length = 693 Score = 903 bits (2334), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/657 (65%), Positives = 527/657 (80%) Query: 22 NDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNI 81 N LRWDLS +QI+ RT +LI QTK+VYD VGT ++V+YE+ L+ LAD+EVTY V+R + Sbjct: 35 NVLRWDLSPEQIKTRTEQLIAQTKQVYDTVGTIALKEVTYENCLQVLADIEVTYIVERTM 94 Query: 82 LDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 141 LDFPQHVS +++R ASTEADKKLS FD+EMSMREDV+QRIV LQE + ++PEA RY Sbjct: 95 LDFPQHVSSDREVRAASTEADKKLSRFDIEMSMREDVFQRIVHLQETCDLEKIKPEARRY 154 Query: 142 LERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE 201 LE+ IK+G+RNGLHL + IK +KK++S LCIDFNKNLNED T L F+ ELG LP+ Sbjct: 155 LEKSIKMGKRNGLHLSEAIRNEIKSMKKRMSELCIDFNKNLNEDDTSLVFSKAELGALPD 214 Query: 202 DFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVT 261 DF++SLEK ++ K KVTLKYPHYFP++KKC VPETRRK+E AF+ RCK+EN AIL++L+ Sbjct: 215 DFIDSLEKTDEDKYKVTLKYPHYFPVMKKCCVPETRRKMEMAFHTRCKQENTAILQQLLP 274 Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321 LRAQ ++LLG++THAD+VLE+N AK++ VA FLD+L+QKLKPLGE ER IL LK+ EC Sbjct: 275 LRAQVAKLLGYNTHADFVLELNTAKSTSRVAAFLDDLSQKLKPLGEAEREFILSLKKKEC 334 Query: 322 ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAF 381 E RG +DG+I AWD+ YYM Q EE +Y VDQ LKEYFP++VVT GLL IYQELLGL+F Sbjct: 335 EERGFEYDGKINAWDLHYYMTQTEELKYSVDQESLKEYFPIEVVTEGLLSIYQELLGLSF 394 Query: 382 HHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSR 441 A W++ V LYT +D A+GEV+G+FYLDLYPREGKY HAACFGLQPGCL DGSR Sbjct: 395 EQVPDAHVWNKSVSLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSR 454 Query: 442 QIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV 501 +++AA+V NF++P A PSLL+HDEV TYFHEFGHVMHQ+C+Q +FA FSGT+VE DFV Sbjct: 455 MMSVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFV 514 Query: 502 EAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVD 561 E PSQMLENWVW+ + L ++S+HY+ G + ELLEKL+ SR NTGL LRQIVL+KVD Sbjct: 515 EVPSQMLENWVWDVDSLRKLSKHYKDGHPITDELLEKLVASRLVNTGLLTLRQIVLSKVD 574 Query: 562 QALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMD 621 Q+LHT D A EYA+ C EILGV ATPGTNMPATFGHLAGGYD QYYGYLWSEV+SMD Sbjct: 575 QSLHTNATLDAASEYAKYCTEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMD 634 Query: 622 MFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGLQ 678 MFH+ FK+EG++N +VGM YR+ IL+PGGS D ML+ FL R+P Q AFL+S+GL Sbjct: 635 MFHSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMSRGLN 691 >5LV0-A nrPDB Length = 686 Score = 901 bits (2329), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/657 (64%), Positives = 523/657 (79%) Query: 22 NDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNI 81 N LRWDLS +QI+ RT ELI QTK+VYD VG E+V+YE+ L+ALADVEV Y V+R + Sbjct: 28 NVLRWDLSPEQIKTRTEELIVQTKQVYDAVGMLGIEEVTYENCLQALADVEVKYIVERTM 87 Query: 82 LDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 141 LDFPQHVS K++R ASTEADK+LS FD+EMSMR D+++RIV LQE ++PEA RY Sbjct: 88 LDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDLGKIKPEARRY 147 Query: 142 LERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE 201 LE+ IK+G+RNGLHLP + Q IK +KK++S LCIDFNKNLNED TFL F+ ELG LP+ Sbjct: 148 LEKSIKMGKRNGLHLPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPD 207 Query: 202 DFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVT 261 DF++SLEK +D K K+TLKYPHYFP++KKC +PETRR++E AFN RCKEEN IL++L+ Sbjct: 208 DFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTIILQQLLP 267 Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321 LR + ++LLG+ THAD+VLEMN AK++ V FLD+L+QKLKPLGE ER IL LK+ EC Sbjct: 268 LRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKEC 327 Query: 322 ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAF 381 + RG +DG+I AWD+ YYM Q EE +Y +DQ LKEYFP++VVT GLL YQELLGL+F Sbjct: 328 KDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSF 387 Query: 382 HHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSR 441 A W++ V LYT +D A+GEV+G+FYLDLYPREGKY HAACFGLQPGCL DGSR Sbjct: 388 EQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSR 447 Query: 442 QIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV 501 +A+AA+V NF++P A PSLL+HDEV TYFH+FGHVMHQ+C+Q +FA FSGT+VE DFV Sbjct: 448 MMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHQFGHVMHQICAQTDFARFSGTNVETDFV 507 Query: 502 EAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVD 561 E PSQMLENWVW+ + L R+S+HY+ GS + +LLEKL+ SR NTGL LRQIVL+KVD Sbjct: 508 EVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVD 567 Query: 562 QALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMD 621 Q+LHT T D A EYA+ C EILGV ATPGTNMPATFGHLAGGYD QYYGYLWSEV+SMD Sbjct: 568 QSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMD 627 Query: 622 MFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGLQ 678 MF++ FK+EG++N +VGM YR+ IL+PGGS D ML FL R+P Q AFL+S+GL Sbjct: 628 MFYSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLHNFLKREPNQKAFLMSRGLH 684 >4KA7-A nrPDB Length = 714 Score = 261 bits (666), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 178/634 (28%), Positives = 306/634 (48%), Gaps = 39/634 (6%) Query: 76 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR 135 TV +++ + V + ++R A + + +F + + + +Y ++E SL Sbjct: 81 TVVWGMINHLKAVKDTPELRAAIEDVQPEKVKFQLRLGQSKPIYNAFKAIRESPDWSSLS 140 Query: 136 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTL-- 193 R +E IK G+ L E +E +I+++L L F++N+ + T + Sbjct: 141 EARQRLVEAQIKEAVLIGIALDDEKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITD 200 Query: 194 -QELGGLPEDFLNSLEKM-----------EDGKLKVTLKYPHYFPLLKKCHVPETRRKVE 241 +E+ GLP L + E+G +TL P Y P+++ R +V Sbjct: 201 KKEIEGLPPSALGLFAQAAVSKGHENATAENGPWIITLDAPSYLPVMQHAKNRALREEVY 260 Query: 242 EAFNCRCKE---ENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDEL 298 A+ R +N AI+ +++ LR +K++LLG++ +A+ + M MA + EL Sbjct: 261 RAYLSRASSGDLDNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMATVEKAA-----EL 315 Query: 299 AQKLKPLGEQERAVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKE 358 +KL+ +E ++ + +G + WD ++ ++ E++Y +++ L+ Sbjct: 316 LEKLRSASWDAAVQDMEDLKSFAKNQGAAESDSMTHWDTTFWSERLRESKYDINEEELRP 375 Query: 359 YFPVQVVTHGLLGIYQELLGLAFHHEEG-ASAWHEDVRLYTARDAASGEVVGKFYLDLYP 417 YF + V GL + + L G+ +G A W+ DVR Y +D+ SG + FY D Y Sbjct: 376 YFSLPKVMDGLFSLAKTLFGIDIEPADGLAPVWNNDVRFYRVKDS-SGNPIAYFYFDPYS 434 Query: 418 REGKYGHAACFG---LQPGCLRQDGSR-QIAIAAMVANFTKPTADAPSLLQHDEVETYFH 473 R + A + + Q GS ++ +A MV N T P D PSL+ EVET FH Sbjct: 435 RPSEKRGGAWMDEVVSRSRVMAQKGSSVRLPVAHMVCNQTPPVGDKPSLMTFREVETVFH 494 Query: 474 EFGHVMHQLCSQAEFAMFSGT-HVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVP 532 +FGH + + ++ + + +G ++E D VE PSQ +ENW + ++ L+ +++HY TG +P Sbjct: 495 QFGHALQHMLTKQDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYETGETLP 554 Query: 533 RELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQ-TDADPAEEY---ARLCQEILGVPA 588 E+ +KL+ +R G F+LRQ+ A VD LHT+ P Y R+ + +P Sbjct: 555 EEVYKKLLAARTFRAGSFSLRQLKFASVDLELHTKYVPGGPESIYDVDQRVSVKTQVIPP 614 Query: 589 TPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSK----VGMDYRS 643 P +F H+ AGGY A YY Y W+EV S D F + F+ G+ + K G +R+ Sbjct: 615 LPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGLDDIKAVKETGQRFRN 673 Query: 644 CILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGL 677 IL GG + + F GR+P + L GL Sbjct: 674 TILALGGGKAPLKVFVEFRGREPSPEPLLRHNGL 707 >4PUT-A nrPDB Length = 721 Score = 256 bits (655), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 181/682 (26%), Positives = 325/682 (47%), Gaps = 41/682 (6%) Query: 28 LSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQH 87 + A + R L++Q + +Q+ ++ + S+ ++ L + +V +++ + Sbjct: 44 VDAHHVRPGIRALLQQLEAELEQL--EKAVEPSWPKLVEPLEKIIDRLSVVWGMINHLKA 101 Query: 88 VSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIK 147 V + ++R A E + +F + + + +Y ++E +SL R +E IK Sbjct: 102 VKDTPELRAAIEEVQPEKVKFQLRLGQSKPIYNAFKAIRESPDWNSLSEARQRLVEAQIK 161 Query: 148 LGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTL---QELGGLPEDFL 204 +G+ L + +E +I+++L L F++N+ + T + +E+ GLP L Sbjct: 162 EAVLSGIALEDDKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSAL 221 Query: 205 NSLEKM-----------EDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKE--- 250 + + G +TL P Y P+++ R +V A+ R Sbjct: 222 GLFAQAAVSKGHETATADTGPWLITLDAPSYLPVMQHAKNRALREEVYRAYLSRASSGDL 281 Query: 251 ENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQER 310 +N AI+ +++ LR +K++LLG+ +A+ + MA + DEL +KL+ Sbjct: 282 DNTAIIDQILKLRLEKAKLLGYRNYAEVSMATKMATVEKA-----DELLEKLRSASWDPA 336 Query: 311 AVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLL 370 +E ++ + +G + WD+ ++ ++ E++Y +++ L+ YF + V L Sbjct: 337 VQDIEDLKSFAKNQGAAEADSLTHWDITFWSERLRESKYDINEEELRPYFSLPKVMDALF 396 Query: 371 GIYQELLGLAFHHEEG-ASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAA--- 426 G+ + L G+ +G A W+ DVR Y +D+ SG FY D Y R + A Sbjct: 397 GLAKTLFGIDVVPADGVAPVWNSDVRFYCVKDS-SGNPTAYFYFDPYSRPSEKRDGAWMD 455 Query: 427 -CFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQ 485 F ++ S ++ +A MV N T P D PSL+ EVET FHEFGH + + ++ Sbjct: 456 EVFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTK 515 Query: 486 AEFAMFSGT-HVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQ 544 + + +G ++E D VE PSQ +ENW + ++ L+ +++HY+TG +P + +KL+ +R Sbjct: 516 EDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGETLPENVYKKLLAART 575 Query: 545 ANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEIL----GVPATPGTNMPATFGH 600 G +LRQ+ A VD LHT+ AE + Q + +P P +F H Sbjct: 576 FRAGSLSLRQLKFATVDLELHTKYMPGGAETIYEVDQRVSIKTQVIPPLPEDRFLCSFSH 635 Query: 601 L-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNSK----VGMDYRSCILRPGGSEDAS 655 + AGGY A YY Y W+EV S D F + F+ G+ + K G +R+ IL GG + Sbjct: 636 IFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPL 694 Query: 656 AMLRRFLGRDPKQDAFLLSKGL 677 + F GR+P + L GL Sbjct: 695 KVFVEFRGREPSPEPLLRHNGL 716 >5L43-A nrPDB Length = 683 Score = 229 bits (583), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 175/590 (29%), Positives = 280/590 (47%), Gaps = 39/590 (6%) Query: 104 KLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQEN 163 KL++ + + ++ RI +++ D L E A LER + R G L QE Sbjct: 116 KLTQHGDAIHLNRPLFARI----KQISPDGLDAEQAWLLERYVTDFVRAGAELGAGDQER 171 Query: 164 IKRIKKKLSLLCIDFNKNL---NEDTTFLPFTLQELGGLPEDFLNSLEKMED-----GKL 215 +K + ++LS L F +NL + + + +L GL +D + + + GK Sbjct: 172 LKALNEELSTLSTRFEQNLLAHTNASAVIVDDVAQLDGLSDDSVKAAAETAKSRGLPGKY 231 Query: 216 KVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLLGFHTH 275 + L P P L + R ++ A R +N ++ + TLRA++++LLG+ TH Sbjct: 232 VIPLVLPTGQPGLAELTDRALRERIHRASIQRGVPDNEELIVRIATLRAERAKLLGYPTH 291 Query: 276 ADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECERRGLPFDGRIRAW 335 A YV+ A T++ V E+ KL P AV + A+ R D + W Sbjct: 292 AAYVVADQTAPTTEAVT----EMLGKLTP-----PAVANAHREADELREQAGHD--LEPW 340 Query: 336 DMRYYMNQVEETRYCVDQNLLKEYFPV-QVVTHGLLGIYQELLGLAFHHEEGASAWHEDV 394 D +Y +V + RY +D ++ YF + +V+ G+ L G+ F +H DV Sbjct: 341 DWSFYAEKVLKERYAIDGRQMRPYFELDRVLRDGVFHAATLLYGITFTERPDLVGYHPDV 400 Query: 395 RLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQ---DGSRQIAIAAMVAN 451 R++ + G +G F D Y R K G A L ++Q +G+R + + + N Sbjct: 401 RVFEVFNE-DGSQLGLFLGDYYARPSKRGGAWMNSL----VKQSTLEGTRPVVVNNL--N 453 Query: 452 FTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENW 511 KP A P+L+ +EV T FHEFGH +H L S+ + FSGT V RDFVE PSQ+ E W Sbjct: 454 IAKPPAGEPTLMTFEEVNTMFHEFGHALHGLFSEVHYPRFSGTAVPRDFVEYPSQVNEMW 513 Query: 512 VWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALHT-QTDA 570 L +RH++TG +P++LL+++++S++ N G + + +D + HT QT Sbjct: 514 AVWPSVLANYARHWQTGDPMPKDLLDRMLKSQKYNQGYKTVEYLAATLLDWSWHTFQTPP 573 Query: 571 DPAE--EYARLCQEILGVPATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSMDMFHTRF 627 + A E+ L + + P F H+ + GY A YY Y+WSEV D F Sbjct: 574 ENALTFEHEALTTAGVDLKLVPPRYRSTYFAHIWSSGYSAGYYSYIWSEVLDADTVDW-F 632 Query: 628 KQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGL 677 + G L + G +R +L GGS D + F GR P+ + L +GL Sbjct: 633 HENGGLLRENGDTFRQKLLSKGGSVDPMTAFQSFRGRTPRIEPLLDRRGL 682 >1Y79-1 nrPDB Length = 680 Score = 198 bits (504), Expect = 5e-51, Method: Compositional matrix adjust. Identities = 169/598 (28%), Positives = 285/598 (47%), Gaps = 36/598 (6%) Query: 104 KLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQEN 163 +L+E ++ + +++ R+ + ++ + L E+ R +E + + G L + + Sbjct: 97 ELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAK 156 Query: 164 IKRIKKKLSLLCIDFNKNL---NEDTTFLPFTLQELGGLPEDFLN-----SLEKMEDGKL 215 +K + + + L FN+ L N+ + + +L G+ E + + EK D K Sbjct: 157 LKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKW 216 Query: 216 KVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENC----AILKELVTLRAQKSRLLG 271 + L P L + TR K+ A R ++ + AI++ LV +RAQ++ LLG Sbjct: 217 LIPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLG 276 Query: 272 FHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAECERRGLPFDGR 331 F +A + + MAKT + F+ E+ + E A I +A +++ F + Sbjct: 277 FPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASI----QAVIDKQQGGFSAQ 332 Query: 332 IRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQ-VVTHGLLGIYQELLGLAFHHEEGASAW 390 WD +Y QV ++ +D+ LK YF + V+ G+ +L G+ F + Sbjct: 333 --PWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVY 390 Query: 391 HEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGS--RQIAIAAM 448 H DVR++ D +G + FY D + R+ K G G G + + + + Sbjct: 391 HPDVRVWEIFDH-NGVGLALFYGDFFARDSKSG-----GAWMGNFVEQSTLNKTHPVIYN 444 Query: 449 VANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQML 508 V N+ KP A P+LL D+V T FHEFGH +H L ++ +A SGT+ RDFVE PSQ+ Sbjct: 445 VCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQIN 504 Query: 509 ENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALH--- 565 E+W + R +RHY++G+A+P EL +K+ + N G + A +D H Sbjct: 505 EHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLE 564 Query: 566 ---TQTDADPAEEYARLCQEILGVPATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSMD 621 D D E A L E + +PA P + F H+ GGY A YY YLW+++ + D Sbjct: 565 ENEAMQDVDDFELRA-LVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD 623 Query: 622 MFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGLQV 679 + F ++G L + G+ +R IL G SED + R++ G+ PK L +GL + Sbjct: 624 GYQW-FVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLNI 680 >5XM3-A nrPDB Length = 627 Score = 32.7 bits (73), Expect = 0.59, Method: Compositional matrix adjust. Identities = 22/100 (22%), Positives = 42/100 (42%), Gaps = 2/100 (2%) Query: 469 ETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTG 528 E + + + L + + SG V D + S+ ENWV + + HY T Sbjct: 3 EMHHSRWSKIGTALAVSSALGLMSGMSVANDKLVELSKSNENWVMQGKDF--SGTHYSTA 60 Query: 529 SAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQT 568 + ++ ++KL S +TG+ N + V+ ++ T Sbjct: 61 KQINKDNVKKLRPSWSFSTGVLNGHEGAPLVVNGTMYIHT 100 >5TQV-A nrPDB Length = 233 Score = 30.8 bits (68), Expect = 1.9, Method: Compositional matrix adjust. Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 24/126 (19%) Query: 355 LLKEYFPVQVVTHGLLGIYQELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLD 414 LL P+ G+L + +G + G + W LY A AA +V+ L Sbjct: 118 LLPILLPLVEDARGVLAVVSSRMG-SISEATGTTGW-----LYRASKAALNDVLRIASL- 170 Query: 415 LYPREGKYGHAACFGLQPGCLRQD-GSRQIAI--AAMVANFTKPTADAPS--------LL 463 + HAAC L PG +R D G Q A+ A V + A+A + Sbjct: 171 ------QTRHAACISLHPGWVRTDMGGAQAALDPATSVTGMRRVIAEAGADVSQSNGRFF 224 Query: 464 QHDEVE 469 Q+D VE Sbjct: 225 QYDGVE 230 >1AVC-A nrPDB Length = 673 Score = 30.4 bits (67), Expect = 3.0, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 43/90 (47%), Gaps = 8/90 (8%) Query: 498 RDFVEAPSQMLENWVWEQEPLLRMSRHYRT--GSAVPRELLEKLIESRQANTGLFNLRQI 555 RD A Q ++N +PL + Y++ G+ + L +++ SR + L N+R+ Sbjct: 587 RDVFVAIVQSVKN-----KPLFFADKLYKSMKGAGTEEKTLTRIMVSR-SEIDLLNIRRE 640 Query: 556 VLAKVDQALHTQTDADPAEEYARLCQEILG 585 + K D++LH + D + + + I G Sbjct: 641 FIEKYDKSLHQAIEGDTSGHFLKALLAICG 670 >4C9I-A nrPDB Length = 162 Score = 28.9 bits (63), Expect = 8.7, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 22/42 (52%), Gaps = 6/42 (14%) Query: 580 CQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMD 621 C EIL PGT TFG + +YGY+ +++S+D Sbjct: 43 CAEILEGDGGPGTIKKITFG------EGSHYGYVKHKIHSID 78 >5E3X-A nrPDB Length = 489 Score = 28.9 bits (63), Expect = 8.8, Method: Compositional matrix adjust. Identities = 40/185 (21%), Positives = 75/185 (40%), Gaps = 26/185 (14%) Query: 466 DEVETYFHEFGHVMHQLCSQAEF-AMFSGTHVERDFVEAPSQMLENWV------W----- 513 + + + HEFGH ++ L EF + G+ F E+ S+ EN V W Sbjct: 246 NSIYSTIHEFGHALYALSIPTEFYGLPIGSSASYGFDESQSRFWENVVGRSLAFWKGIYS 305 Query: 514 ---EQEPLLR---MSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQ 567 E P +R + +R + V R + +A+ +NL I+ ++++ L Sbjct: 306 KFIEIVPEMRGYSVEELWRAVNRVQRSFIRT-----EADEVTYNLHIIIRFEIERELING 360 Query: 568 --TDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHT 625 + D +++ L ++ LG+ T H GG + Y +Y+ +F Sbjct: 361 ELSVKDVPDKWNELYKKYLGLDVPNNTLGCMQDPHWFGGNFGYFPTYALGNLYAAQIFE- 419 Query: 626 RFKQE 630 + K+E Sbjct: 420 KLKEE 424 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2O36-A nrPDB 1087 0.0 5LV0-A nrPDB 1005 0.0 4FXY-P nrPDB 1005 0.0 4PUT-A nrPDB 853 0.0 4KA7-A nrPDB 831 0.0 5L43-A nrPDB 730 0.0 1Y79-1 nrPDB 720 0.0 Sequences not found previously or not previously below threshold: 3CE2-A nrPDB 40 0.004 5XM3-A nrPDB 37 0.026 1K7G-A nrPDB 36 0.055 3E8J-A nrPDB 34 0.16 4EGL-A nrPDB 34 0.24 5ZJK-A nrPDB 34 0.25 5CZW-A nrPDB 34 0.25 2QR4-A nrPDB 34 0.30 3I05-A nrPDB 33 0.34 3JCR-F nrPDB 33 0.49 5L3D-A nrPDB 33 0.56 3ABT-A nrPDB 33 0.56 2FPQ-A nrPDB 32 1.1 3R6N-A nrPDB 32 1.3 2YBB-4 nrPDB 31 1.4 6Q8Y-z nrPDB 31 1.5 5E3X-A nrPDB 31 2.0 6F1U-X nrPDB 30 2.8 2ROH-A nrPDB 30 3.2 2OCP-A nrPDB 30 4.1 2I1J-A nrPDB 30 4.7 CONVERGED! >2O36-A nrPDB Length = 674 Score = 1087 bits (2811), Expect = 0.0, Method: Composition-based stats. Identities = 670/674 (99%), Positives = 670/674 (99%) Query: 16 SPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTY 75 SPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTY Sbjct: 1 SPCSVVNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTY 60 Query: 76 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR 135 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR Sbjct: 61 TVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLR 120 Query: 136 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQE 195 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQE Sbjct: 121 PEAARYLERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQE 180 Query: 196 LGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAI 255 LGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFN RCKEEN AI Sbjct: 181 LGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNSRCKEENSAI 240 Query: 256 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE 315 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE Sbjct: 241 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE 300 Query: 316 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQE 375 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQE Sbjct: 301 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQE 360 Query: 376 LLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL 435 LLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL Sbjct: 361 LLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL 420 Query: 436 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTH 495 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEV TYFHEFGHVMHQLCSQAEFAMFSGTH Sbjct: 421 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVRTYFHEFGHVMHQLCSQAEFAMFSGTH 480 Query: 496 VERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQI 555 VE DFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQI Sbjct: 481 VETDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQI 540 Query: 556 VLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS 615 VLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS Sbjct: 541 VLAKVDQALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWS 600 Query: 616 EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK 675 EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK Sbjct: 601 EVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSK 660 Query: 676 GLQVGGCEPEPQVC 689 GLQVGGCEPEPQVC Sbjct: 661 GLQVGGCEPEPQVC 674 >5LV0-A nrPDB Length = 686 Score = 1005 bits (2599), Expect = 0.0, Method: Composition-based stats. Identities = 425/657 (64%), Positives = 523/657 (79%) Query: 22 NDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNI 81 N LRWDLS +QI+ RT ELI QTK+VYD VG E+V+YE+ L+ALADVEV Y V+R + Sbjct: 28 NVLRWDLSPEQIKTRTEELIVQTKQVYDAVGMLGIEEVTYENCLQALADVEVKYIVERTM 87 Query: 82 LDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 141 LDFPQHVS K++R ASTEADK+LS FD+EMSMR D+++RIV LQE ++PEA RY Sbjct: 88 LDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDLGKIKPEARRY 147 Query: 142 LERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE 201 LE+ IK+G+RNGLHLP + Q IK +KK++S LCIDFNKNLNED TFL F+ ELG LP+ Sbjct: 148 LEKSIKMGKRNGLHLPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPD 207 Query: 202 DFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVT 261 DF++SLEK +D K K+TLKYPHYFP++KKC +PETRR++E AFN RCKEEN IL++L+ Sbjct: 208 DFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTIILQQLLP 267 Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321 LR + ++LLG+ THAD+VLEMN AK++ V FLD+L+QKLKPLGE ER IL LK+ EC Sbjct: 268 LRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKEC 327 Query: 322 ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAF 381 + RG +DG+I AWD+ YYM Q EE +Y +DQ LKEYFP++VVT GLL YQELLGL+F Sbjct: 328 KDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSF 387 Query: 382 HHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSR 441 A W++ V LYT +D A+GEV+G+FYLDLYPREGKY HAACFGLQPGCL DGSR Sbjct: 388 EQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSR 447 Query: 442 QIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV 501 +A+AA+V NF++P A PSLL+HDEV TYFH+FGHVMHQ+C+Q +FA FSGT+VE DFV Sbjct: 448 MMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHQFGHVMHQICAQTDFARFSGTNVETDFV 507 Query: 502 EAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVD 561 E PSQMLENWVW+ + L R+S+HY+ GS + +LLEKL+ SR NTGL LRQIVL+KVD Sbjct: 508 EVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVD 567 Query: 562 QALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMD 621 Q+LHT T D A EYA+ C EILGV ATPGTNMPATFGHLAGGYD QYYGYLWSEV+SMD Sbjct: 568 QSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMD 627 Query: 622 MFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGLQ 678 MF++ FK+EG++N +VGM YR+ IL+PGGS D ML FL R+P Q AFL+S+GL Sbjct: 628 MFYSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLHNFLKREPNQKAFLMSRGLH 684 >4FXY-P nrPDB Length = 693 Score = 1005 bits (2598), Expect = 0.0, Method: Composition-based stats. Identities = 428/657 (65%), Positives = 527/657 (80%) Query: 22 NDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNI 81 N LRWDLS +QI+ RT +LI QTK+VYD VGT ++V+YE+ L+ LAD+EVTY V+R + Sbjct: 35 NVLRWDLSPEQIKTRTEQLIAQTKQVYDTVGTIALKEVTYENCLQVLADIEVTYIVERTM 94 Query: 82 LDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 141 LDFPQHVS +++R ASTEADKKLS FD+EMSMREDV+QRIV LQE + ++PEA RY Sbjct: 95 LDFPQHVSSDREVRAASTEADKKLSRFDIEMSMREDVFQRIVHLQETCDLEKIKPEARRY 154 Query: 142 LERLIKLGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPE 201 LE+ IK+G+RNGLHL + IK +KK++S LCIDFNKNLNED T L F+ ELG LP+ Sbjct: 155 LEKSIKMGKRNGLHLSEAIRNEIKSMKKRMSELCIDFNKNLNEDDTSLVFSKAELGALPD 214 Query: 202 DFLNSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVT 261 DF++SLEK ++ K KVTLKYPHYFP++KKC VPETRRK+E AF+ RCK+EN AIL++L+ Sbjct: 215 DFIDSLEKTDEDKYKVTLKYPHYFPVMKKCCVPETRRKMEMAFHTRCKQENTAILQQLLP 274 Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321 LRAQ ++LLG++THAD+VLE+N AK++ VA FLD+L+QKLKPLGE ER IL LK+ EC Sbjct: 275 LRAQVAKLLGYNTHADFVLELNTAKSTSRVAAFLDDLSQKLKPLGEAEREFILSLKKKEC 334 Query: 322 ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLLGIYQELLGLAF 381 E RG +DG+I AWD+ YYM Q EE +Y VDQ LKEYFP++VVT GLL IYQELLGL+F Sbjct: 335 EERGFEYDGKINAWDLHYYMTQTEELKYSVDQESLKEYFPIEVVTEGLLSIYQELLGLSF 394 Query: 382 HHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGSR 441 A W++ V LYT +D A+GEV+G+FYLDLYPREGKY HAACFGLQPGCL DGSR Sbjct: 395 EQVPDAHVWNKSVSLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSR 454 Query: 442 QIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV 501 +++AA+V NF++P A PSLL+HDEV TYFHEFGHVMHQ+C+Q +FA FSGT+VE DFV Sbjct: 455 MMSVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFV 514 Query: 502 EAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVD 561 E PSQMLENWVW+ + L ++S+HY+ G + ELLEKL+ SR NTGL LRQIVL+KVD Sbjct: 515 EVPSQMLENWVWDVDSLRKLSKHYKDGHPITDELLEKLVASRLVNTGLLTLRQIVLSKVD 574 Query: 562 QALHTQTDADPAEEYARLCQEILGVPATPGTNMPATFGHLAGGYDAQYYGYLWSEVYSMD 621 Q+LHT D A EYA+ C EILGV ATPGTNMPATFGHLAGGYD QYYGYLWSEV+SMD Sbjct: 575 QSLHTNATLDAASEYAKYCTEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMD 634 Query: 622 MFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKGLQ 678 MFH+ FK+EG++N +VGM YR+ IL+PGGS D ML+ FL R+P Q AFL+S+GL Sbjct: 635 MFHSCFKKEGIMNPEVGMKYRNLILKPGGSLDGMDMLQNFLQREPNQKAFLMSRGLN 691 >4PUT-A nrPDB Length = 721 Score = 853 bits (2204), Expect = 0.0, Method: Composition-based stats. Identities = 180/682 (26%), Positives = 324/682 (47%), Gaps = 41/682 (6%) Query: 28 LSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQH 87 + A + R L++Q + +Q+ ++ + S+ ++ L + +V +++ + Sbjct: 44 VDAHHVRPGIRALLQQLEAELEQL--EKAVEPSWPKLVEPLEKIIDRLSVVWGMINHLKA 101 Query: 88 VSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIK 147 V + ++R A E + +F + + + +Y ++E +SL R +E IK Sbjct: 102 VKDTPELRAAIEEVQPEKVKFQLRLGQSKPIYNAFKAIRESPDWNSLSEARQRLVEAQIK 161 Query: 148 LGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPF---TLQELGGLPEDFL 204 +G+ L + +E +I+++L L F++N+ + T +E+ GLP L Sbjct: 162 EAVLSGIALEDDKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSAL 221 Query: 205 NSLEK-----------MEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKE--- 250 + + G +TL P Y P+++ R +V A+ R Sbjct: 222 GLFAQAAVSKGHETATADTGPWLITLDAPSYLPVMQHAKNRALREEVYRAYLSRASSGDL 281 Query: 251 ENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQER 310 +N AI+ +++ LR +K++LLG+ +A+ + MA + DEL +KL+ Sbjct: 282 DNTAIIDQILKLRLEKAKLLGYRNYAEVSMATKMATVEKA-----DELLEKLRSASWDPA 336 Query: 311 AVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLL 370 +E ++ + +G + WD+ ++ ++ E++Y +++ L+ YF + V L Sbjct: 337 VQDIEDLKSFAKNQGAAEADSLTHWDITFWSERLRESKYDINEEELRPYFSLPKVMDALF 396 Query: 371 GIYQELLGLAFHHEEG-ASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAAC-- 427 G+ + L G+ +G A W+ DVR Y +D+ SG FY D Y R + A Sbjct: 397 GLAKTLFGIDVVPADGVAPVWNSDVRFYCVKDS-SGNPTAYFYFDPYSRPSEKRDGAWMD 455 Query: 428 --FGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQ 485 F ++ S ++ +A MV N T P D PSL+ EVET FHEFGH + + ++ Sbjct: 456 EVFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTK 515 Query: 486 AEFAMFSGT-HVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQ 544 + + +G ++E D VE PSQ +ENW + ++ L+ +++HY+TG +P + +KL+ +R Sbjct: 516 EDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGETLPENVYKKLLAART 575 Query: 545 ANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEI----LGVPATPGTNMPATFGH 600 G +LRQ+ A VD LHT+ AE + Q + +P P +F H Sbjct: 576 FRAGSLSLRQLKFATVDLELHTKYMPGGAETIYEVDQRVSIKTQVIPPLPEDRFLCSFSH 635 Query: 601 L-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNS----KVGMDYRSCILRPGGSEDAS 655 + AGGY A YY Y W+EV S D F + F+ G+ + + G +R+ IL GG + Sbjct: 636 IFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPL 694 Query: 656 AMLRRFLGRDPKQDAFLLSKGL 677 + F GR+P + L GL Sbjct: 695 KVFVEFRGREPSPEPLLRHNGL 716 >4KA7-A nrPDB Length = 714 Score = 831 bits (2147), Expect = 0.0, Method: Composition-based stats. Identities = 178/682 (26%), Positives = 317/682 (46%), Gaps = 41/682 (6%) Query: 28 LSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQH 87 + A + R + ++ + ++ ++ L + TV +++ + Sbjct: 35 VDASHVRPGIRA--LLQHLEAELEELEKSVEPTWPKLVEPLEKIVDRLTVVWGMINHLKA 92 Query: 88 VSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIK 147 V + ++R A + + +F + + + +Y ++E SL R +E IK Sbjct: 93 VKDTPELRAAIEDVQPEKVKFQLRLGQSKPIYNAFKAIRESPDWSSLSEARQRLVEAQIK 152 Query: 148 LGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPF---TLQELGGLPEDFL 204 G+ L E +E +I+++L L F++N+ + T +E+ GLP L Sbjct: 153 EAVLIGIALDDEKREEFNKIEQELEKLSHKFSENVLDATKKFEKLITDKKEIEGLPPSAL 212 Query: 205 NSLEK-----------MEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKE--- 250 + E+G +TL P Y P+++ R +V A+ R Sbjct: 213 GLFAQAAVSKGHENATAENGPWIITLDAPSYLPVMQHAKNRALREEVYRAYLSRASSGDL 272 Query: 251 ENCAILKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQER 310 +N AI+ +++ LR +K++LLG++ +A+ + M MA + EL +KL+ Sbjct: 273 DNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMATVEKAA-----ELLEKLRSASWDAA 327 Query: 311 AVILELKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQVVTHGLL 370 +E ++ + +G + WD ++ ++ E++Y +++ L+ YF + V GL Sbjct: 328 VQDMEDLKSFAKNQGAAESDSMTHWDTTFWSERLRESKYDINEEELRPYFSLPKVMDGLF 387 Query: 371 GIYQELLGLAFHHEEG-ASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACF- 428 + + L G+ +G A W+ DVR Y +D+ SG + FY D Y R + A Sbjct: 388 SLAKTLFGIDIEPADGLAPVWNNDVRFYRVKDS-SGNPIAYFYFDPYSRPSEKRGGAWMD 446 Query: 429 ---GLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQ 485 ++ S ++ +A MV N T P D PSL+ EVET FH+FGH + + ++ Sbjct: 447 EVVSRSRVMAQKGSSVRLPVAHMVCNQTPPVGDKPSLMTFREVETVFHQFGHALQHMLTK 506 Query: 486 AEFAMFSGT-HVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQ 544 + + +G ++E D VE PSQ +ENW + ++ L+ +++HY TG +P E+ +KL+ +R Sbjct: 507 QDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYETGETLPEEVYKKLLAART 566 Query: 545 ANTGLFNLRQIVLAKVDQALHTQT-DADPAEEY---ARLCQEILGVPATPGTNMPATFGH 600 G F+LRQ+ A VD LHT+ P Y R+ + +P P +F H Sbjct: 567 FRAGSFSLRQLKFASVDLELHTKYVPGGPESIYDVDQRVSVKTQVIPPLPEDRFLCSFSH 626 Query: 601 L-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGVLNS----KVGMDYRSCILRPGGSEDAS 655 + AGGY A YY Y W+EV S D F + F+ G+ + + G +R+ IL GG + Sbjct: 627 IFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPL 685 Query: 656 AMLRRFLGRDPKQDAFLLSKGL 677 + F GR+P + L GL Sbjct: 686 KVFVEFRGREPSPEPLLRHNGL 707 >5L43-A nrPDB Length = 683 Score = 730 bits (1885), Expect = 0.0, Method: Composition-based stats. Identities = 187/661 (28%), Positives = 302/661 (45%), Gaps = 37/661 (5%) Query: 31 QQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHVSP 90 + R + EQ V G E ++++T+ AL T + F Q S Sbjct: 45 HYVPAFERGMAEQLAEVEAIAGDTEA--PTFDNTVAALERSGQVLTRVSAVF-FNQSSSD 101 Query: 91 S-KDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLG 149 + ++ + KL++ + + ++ RI +++ D L E A LER + Sbjct: 102 TNPTVQEIQKQIIPKLTQHGDAIHLNRPLFARI----KQISPDGLDAEQAWLLERYVTDF 157 Query: 150 RRNGLHLPRETQENIKRIKKKLSLLCIDFNKNL---NEDTTFLPFTLQELGGLPEDFLNS 206 R G L QE +K + ++LS L F +NL + + + +L GL +D + + Sbjct: 158 VRAGAELGAGDQERLKALNEELSTLSTRFEQNLLAHTNASAVIVDDVAQLDGLSDDSVKA 217 Query: 207 LEKMED-----GKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVT 261 + GK + L P P L + R ++ A R +N ++ + T Sbjct: 218 AAETAKSRGLPGKYVIPLVLPTGQPGLAELTDRALRERIHRASIQRGVPDNEELIVRIAT 277 Query: 262 LRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILELKRAEC 321 LRA++++LLG+ THA YV+ A T++ V E+ KL P AV + A+ Sbjct: 278 LRAERAKLLGYPTHAAYVVADQTAPTTEAVT----EMLGKLTP-----PAVANAHREADE 328 Query: 322 ERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPV-QVVTHGLLGIYQELLGLA 380 R D + WD +Y +V + RY +D ++ YF + +V+ G+ L G+ Sbjct: 329 LREQAGHD--LEPWDWSFYAEKVLKERYAIDGRQMRPYFELDRVLRDGVFHAATLLYGIT 386 Query: 381 FHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLRQDGS 440 F +H DVR++ + G +G F D Y R K G A L + G+ Sbjct: 387 FTERPDLVGYHPDVRVFEVFNE-DGSQLGLFLGDYYARPSKRGGAWMNSLVKQSTLE-GT 444 Query: 441 RQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDF 500 R + + + N KP A P+L+ +EV T FHEFGH +H L S+ + FSGT V RDF Sbjct: 445 RPVVVNNL--NIAKPPAGEPTLMTFEEVNTMFHEFGHALHGLFSEVHYPRFSGTAVPRDF 502 Query: 501 VEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKV 560 VE PSQ+ E W L +RH++TG +P++LL+++++S++ N G + + + Sbjct: 503 VEYPSQVNEMWAVWPSVLANYARHWQTGDPMPKDLLDRMLKSQKYNQGYKTVEYLAATLL 562 Query: 561 DQALHT-QTDADPAE--EYARLCQEILGVPATPGTNMPATFGHL-AGGYDAQYYGYLWSE 616 D + HT QT + A E+ L + + P F H+ + GY A YY Y+WSE Sbjct: 563 DWSWHTFQTPPENALTFEHEALTTAGVDLKLVPPRYRSTYFAHIWSSGYSAGYYSYIWSE 622 Query: 617 VYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRDPKQDAFLLSKG 676 V D F + G L + G +R +L GGS D + F GR P+ + L +G Sbjct: 623 VLDADTVDW-FHENGGLLRENGDTFRQKLLSKGGSVDPMTAFQSFRGRTPRIEPLLDRRG 681 Query: 677 L 677 L Sbjct: 682 L 682 >1Y79-1 nrPDB Length = 680 Score = 720 bits (1859), Expect = 0.0, Method: Composition-based stats. Identities = 175/674 (25%), Positives = 308/674 (45%), Gaps = 37/674 (5%) Query: 28 LSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQH 87 ++ E ++Q + + + + +T+ AL T ++ Sbjct: 22 IANHHYRPAFDEGMQQKRAEIAAIA-LNPQMPDFNNTILALEQSGELLTRVTSVFFAMTA 80 Query: 88 VSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIK 147 + +++ + +L+E ++ + +++ R+ + ++ + L E+ R +E + + Sbjct: 81 AHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQ 140 Query: 148 LGRRNGLHLPRETQENIKRIKKKLSLLCIDFNKNL---NEDTTFLPFTLQELGGLPEDFL 204 G L + + +K + + + L FN+ L N+ + + +L G+ E + Sbjct: 141 RFVLAGAKLAQADKAKLKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEI 200 Query: 205 N-----SLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENC----AI 255 + EK D K + L P L + TR K+ A R ++ + AI Sbjct: 201 ALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAI 260 Query: 256 LKELVTLRAQKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPLGEQERAVILE 315 ++ LV +RAQ++ LLGF +A + + MAKT + F+ E+ + E A I Sbjct: 261 IQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASI-- 318 Query: 316 LKRAECERRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPVQ-VVTHGLLGIYQ 374 +A +++ F + WD +Y QV ++ +D+ LK YF + V+ G+ Sbjct: 319 --QAVIDKQQGGFSAQ--PWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTAN 374 Query: 375 ELLGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGC 434 +L G+ F +H DVR++ D +G + FY D + R+ K G A G Sbjct: 375 QLFGIKFVERFDIPVYHPDVRVWEIFDH-NGVGLALFYGDFFARDSKSGGAWM-----GN 428 Query: 435 LRQDGS--RQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFS 492 + + + + V N+ KP A P+LL D+V T FHEFGH +H L ++ +A S Sbjct: 429 FVEQSTLNKTHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLS 488 Query: 493 GTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNL 552 GT+ RDFVE PSQ+ E+W + R +RHY++G+A+P EL +K+ + N G Sbjct: 489 GTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMS 548 Query: 553 RQIVLAKVDQALH------TQTDADPAEEYARLCQEILGVPATPGTNMPATFGHL-AGGY 605 + A +D H D D E A L E + +PA P + F H+ GGY Sbjct: 549 ELLSAALLDMRWHCLEENEAMQDVDDFELRA-LVAENMDLPAIPPRYRSSYFAHIFGGGY 607 Query: 606 DAQYYGYLWSEVYSMDMFHTRFKQEGVLNSKVGMDYRSCILRPGGSEDASAMLRRFLGRD 665 A YY YLW+++ + D + F ++G L + G+ +R IL G SED + R++ G+ Sbjct: 608 AAGYYAYLWTQMLADDGYQW-FVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKA 666 Query: 666 PKQDAFLLSKGLQV 679 PK L +GL + Sbjct: 667 PKIMPMLQHRGLNI 680 >3CE2-A nrPDB Length = 618 Score = 39.7 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 39/226 (17%), Positives = 73/226 (32%), Gaps = 38/226 (16%) Query: 467 EVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYR 526 +V HE GH MH S+ F E S + E + + +L+ S Sbjct: 396 DVSVIAHEGGHSMHSYFSRKHQP-FHDAQYPIFLAEIASTLNEMLLM--DSMLKESDSKE 452 Query: 527 TGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGV 586 + L+ + + RQ++ A + +H A E+ GV Sbjct: 453 EKITILTRCLDTIFST--------LFRQVLFASFEYDIH------HAAEH--------GV 490 Query: 587 PATPGTNMPATFGHLAGGYDAQYYGY------LWSEVYSMDMFHTRFKQEGVLNSKVGMD 640 P T + +T+ +L + + + W+ + ++ + + + Sbjct: 491 PLT-EEYLSSTYKNLQNEFYGEIITFDVLSNIEWARI--PHFYYNFYVYQYATGIIAALC 547 Query: 641 YRSCILRPGGSEDASAMLRRFLGRDPKQDAF--LLSKGLQVGGCEP 684 + IL ++A FL L GL +G EP Sbjct: 548 FLEKILN--NEDNALNSYLNFLKSGGSDFPLEILKKSGLDMGTVEP 591 >5XM3-A nrPDB Length = 627 Score = 37.0 bits (84), Expect = 0.026, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 2/81 (2%) Query: 489 AMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTG 548 + SG V D + S+ ENWV + + HY T + ++ ++KL S +TG Sbjct: 23 GLMSGMSVANDKLVELSKSNENWVMQGKDFS--GTHYSTAKQINKDNVKKLRPSWSFSTG 80 Query: 549 LFNLRQIVLAKVDQALHTQTD 569 + N + V+ ++ T Sbjct: 81 VLNGHEGAPLVVNGTMYIHTP 101 >1K7G-A nrPDB Length = 479 Score = 35.9 bits (81), Expect = 0.055, Method: Composition-based stats. Identities = 33/196 (16%), Positives = 62/196 (31%), Gaps = 23/196 (11%) Query: 400 RDAASGEVVGKFYLDLYPREGKYG---HAACFGLQPGCLRQDGSRQIAIAAMVANFTKPT 456 +G Y R+ + PG + GS +N P Sbjct: 120 FTEVTGNKSANITFGNYTRDASGNLDYGTQAYAYYPGNYQGAGSSWY--NYNQSNIRNPG 177 Query: 457 ADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFV----EAPSQMLENWV 512 ++ +T+ HE GH + L E+ G D V ++ W Sbjct: 178 SEEYGR------QTFTHEIGHAL-GLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWG 230 Query: 513 WEQEPLLRMSRHYRTGSAVPREL--LEKLIESR-QANTGLFNLRQIVLAKVDQALHTQTD 569 E E + HY G+ + ++ +++L + TG + + D+ +T TD Sbjct: 231 -ENETGADYNGHY-GGAPMIDDIAAIQRLYGANMTTRTG--DSVYGFNSNTDRDFYTATD 286 Query: 570 ADPAEEYARLCQEILG 585 + A ++ Sbjct: 287 SSKALIFSVWDAGGTD 302 >3E8J-A nrPDB Length = 306 Score = 34.3 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 55/165 (33%), Gaps = 16/165 (9%) Query: 356 LKEYFPVQVVTHGLLGIYQEL---LGLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFY 412 L Y+ V+ + + QEL G + A W ++ R+ A G G F+ Sbjct: 137 LTPYYAVEEDCYYFHHVAQELCRPFGADVYERFKA--WCDEYFFIPHRNEARGIG-GLFF 193 Query: 413 LDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYF 472 DL + A + G + I I N T T + + Sbjct: 194 DDLNEWPFEKCFAFMQAVGKGFI----DAYIPIVNRRKN-TPYTEQQVEFQEFR--RGRY 246 Query: 473 HEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEP 517 EF V+ + +F + SG E + P + + W EP Sbjct: 247 AEFNLVIDR---GTKFGLQSGGRTESILMSLPPRARWGYNWHPEP 288 >4EGL-A nrPDB Length = 177 Score = 34.0 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 32/83 (38%), Gaps = 1/83 (1%) Query: 399 ARDAASGEVVGKFYLDLY-PREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTA 457 RD +G +G +++ ++ + GL+ S + ++ + + Sbjct: 35 IRDKVAGHSLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYIS 94 Query: 458 DAPSLLQHDEVETYFHEFGHVMH 480 P + +VE F FG +++ Sbjct: 95 GLPRTMTQKDVEDMFSRFGRIIN 117 >5ZJK-A nrPDB Length = 213 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 15/31 (48%), Gaps = 4/31 (12%) Query: 469 ETYFHEFGHVMHQLCSQAEFAMFSGTHVERD 499 T HEFGH + + + + + T++ D Sbjct: 99 RTVIHEFGHAL-GMIHEHQHPL---TNIPWD 125 >5CZW-A nrPDB Length = 238 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 15/31 (48%), Gaps = 4/31 (12%) Query: 469 ETYFHEFGHVMHQLCSQAEFAMFSGTHVERD 499 T HEFGH + + + + + T++ D Sbjct: 133 RTVIHEFGHAL-GMIHEHQHPL---TNIPWD 159 >2QR4-A nrPDB Length = 587 Score = 33.6 bits (75), Expect = 0.30, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 24/73 (32%), Gaps = 9/73 (12%) Query: 464 QHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVW--------EQ 515 D++ T HE GH +H +++ G E S EN + + Sbjct: 360 TLDQLFTLVHEMGHSVHSYFTRSNQPYVYG-DYSIFLAEIASTTNENILTEYLLETEKDP 418 Query: 516 EPLLRMSRHYRTG 528 + HY G Sbjct: 419 RVRAYVLNHYLDG 431 >3I05-A nrPDB Length = 395 Score = 33.2 bits (74), Expect = 0.34, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 3/92 (3%) Query: 477 HVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAVPRELL 536 H + + G +VE V+ P Q L ++ + E L R+ + Y G + E+ Sbjct: 295 HAFSGGGATKQEHFLLGANVE---VDVPIQWLSFFLEDDEELARVKKEYMLGRIMTGEVK 351 Query: 537 EKLIESRQANTGLFNLRQIVLAKVDQALHTQT 568 + LI + A T ++ ++ D L T T Sbjct: 352 KLLINTITAITKTHQEKRKLVTDEDVQLFTST 383 >3JCR-F nrPDB Length = 820 Score = 32.8 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 61/160 (38%), Gaps = 18/160 (11%) Query: 205 NSLEKMEDGKLKVTLKYPHYFPLLKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRA 264 E+ + K +K + + K+ + E+ L R Sbjct: 236 KIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRKFVFEWD-ASEDTSIDYNPLYKERH 294 Query: 265 QKSRLLGFHTHADYVLEMNMAKTSQTVATFLDELAQKLKPL--GEQERAVILELKRAECE 322 Q +LLG ++ +++ + + + F +L +K + L EQE A + +L++ E + Sbjct: 295 QV-QLLG----RGFIAGIDLKQQKREQSRFYGDLMEKRRTLEEKEQEEARLRKLRKKEAK 349 Query: 323 RRGLPFDGRIRAWDMRYYMNQVEETRYCVDQNLLKEYFPV 362 +R WD R++ + + D + +E + + Sbjct: 350 QR----------WDDRHWSQKKLDEMTDRDWRIFREDYSI 379 >5L3D-A nrPDB Length = 852 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 24/121 (19%) Query: 86 QHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERL 145 +HV + E KK+ + E+ +++ ++V L+EK ++ +Y E Sbjct: 421 KHVKDEQ------IEHWKKIVKTQEEL---KELLNKMVNLKEK-----IKELHQQYKEA- 465 Query: 146 IKLGRRNGLHLPRETQENI--KRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDF 203 + + PR+ K + L+ LC ++++ L E L LQEL P Sbjct: 466 ------SEVKPPRDITAEFLVKSKHRDLTALCKEYDE-LAETQGKLEEKLQELEANPPSD 518 Query: 204 L 204 + Sbjct: 519 V 519 >3ABT-A nrPDB Length = 662 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 50/121 (41%), Gaps = 24/121 (19%) Query: 86 QHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERL 145 +HV + E KK+ + E+ +++ ++V L+EK ++ +Y E Sbjct: 250 KHVKDEQ------IEHWKKIVKTQEEL---KELLNKMVNLKEK-----IKELHQQYKEA- 294 Query: 146 IKLGRRNGLHLPRETQENI--KRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDF 203 + + PR+ K + L+ LC ++++ L E L LQEL P Sbjct: 295 ------SEVKPPRDITAEFLVKSKHRDLTALCKEYDE-LAETQGKLEEKLQELEANPPSD 347 Query: 204 L 204 + Sbjct: 348 V 348 >2FPQ-A nrPDB Length = 444 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 17/49 (34%), Gaps = 10/49 (20%) Query: 451 NFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFAMFSGTHVERD 499 N + S+ D V HE H +HQL G ++ D Sbjct: 216 NQSSAVLGK-SIFCMDPVIALMHELTHSLHQLY---------GINIPSD 254 >3R6N-A nrPDB Length = 450 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 49/126 (38%), Gaps = 12/126 (9%) Query: 21 VNDLRWDLSAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRN 80 + D RW L + + R + I Q + Y+ + FE + + L+ L ++ + + Sbjct: 51 IGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDH---LRQLQNIIQATSREIM 107 Query: 81 ILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAAR 140 ++ + D +T +K F + MS E ++ + + L+ E+ + Sbjct: 108 WINDCEEEELLYDWSDKNTNIAQKQEAFSIRMSQLE---------VKEKELNKLKQESDQ 158 Query: 141 YLERLI 146 + Sbjct: 159 LVLNQH 164 >2YBB-4 nrPDB Length = 409 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 44/116 (37%), Gaps = 2/116 (1%) Query: 30 AQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILD-FPQHV 88 ++ ++L+E D+ E + + + + + + + Sbjct: 183 PEEFVPELKKLLEVLPHRIDEYEALFAESPIFYERARGVGVIPPEVAIDLGLTGGSLRAS 242 Query: 89 SPSKDIRTASTEADKKLSEFDVEMSMREDVYQR-IVWLQEKVQKDSLRPEAARYLE 143 + D+R A + + FDV + R DV+ R +V ++E + + +A LE Sbjct: 243 GVNYDVRKAYPYSGYETYTFDVPLGERGDVFDRMLVRIREMRESVKIIKQALERLE 298 >6Q8Y-z nrPDB Length = 916 Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 66/208 (31%), Gaps = 23/208 (11%) Query: 29 SAQQIEERTRELIEQTKRVYDQVGTQEFEDVSYESTLKALADVEVTYTVQRNILDFPQHV 88 + I T + + TK + + + D + + EV + I++F +H+ Sbjct: 127 DSNSITPGTEFMAKLTKNLQYFIHDKISNDSKWREVQIIFSGHEVPGEGEHKIMNFIRHL 186 Query: 89 SPSKDI----RTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLER 144 KD R D L + + L+E+V E Sbjct: 187 KSQKDFNQNTRHCIYGLDADLIMLGLSTH--GPHFA---LLREEVTFGRRNSEKKSL--- 238 Query: 145 LIKLGRRNGLHLPRETQE-NIKRIKKKLSLLCIDFN-KNLNEDTTFLPFTLQELGGLPED 202 + L L RE E K I ++ ++N + + +D + F + D Sbjct: 239 EHQNFYLLHLSLLREYMELEFKEIADEMQ---FEYNFERILDDFILVMFVIG------ND 289 Query: 203 FLNSLEKMEDGKLKVTLKYPHYFPLLKK 230 FL +L + K + + L Sbjct: 290 FLPNLPDLHLNKGAFPVLLQTFKEALLH 317 >5E3X-A nrPDB Length = 489 Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 35/235 (14%), Positives = 78/235 (33%), Gaps = 30/235 (12%) Query: 466 DEVETYFHEFGHVMHQLCSQAE-FAMFSGTHVERDFVEAPSQMLEN-----WVWEQEPLL 519 + + + HEFGH ++ L E + + G+ F E+ S+ EN + + Sbjct: 246 NSIYSTIHEFGHALYALSIPTEFYGLPIGSSASYGFDESQSRFWENVVGRSLAFWKGIYS 305 Query: 520 RM------------SRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQ 567 + +R + V R + + N + +I ++ L + Sbjct: 306 KFIEIVPEMRGYSVEELWRAVNRVQRSFIRTEADEVTYNLHIIIRFEIERELINGELSVK 365 Query: 568 TDADPAEEYARLCQEILGVPATPGTNMPATFG-HLAGGYDAQYYGYLWSEVYSMDMFHTR 626 D E + + LG+ P + H GG + Y +Y+ +F Sbjct: 366 DVPDKWNELYK---KYLGLD-VPNNTLGCMQDPHWFGGNFGYFPTYALGNLYAAQIFEKL 421 Query: 627 FKQEGVLNSKVGMDY-------RSCILRPGGSEDASAMLRRFLGRDPKQDAFLLS 674 ++ ++ + I G + S +++ G+ ++F+ Sbjct: 422 KEEINFEEVVSAGNFEIIKNFLKEKIHSKGKMYEPSDLIKIVTGKPLSYESFVRY 476 >6F1U-X nrPDB Length = 577 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 21/150 (14%), Positives = 53/150 (35%), Gaps = 4/150 (2%) Query: 91 SKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGR 150 ++D+ + K+L++ + + +R +E + + E +++L Sbjct: 127 NQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREG-EWEGRVSELETDVKQLQDELE 185 Query: 151 RNGLHLPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKM 210 R LHL +E + + ++LS L+ + ++ L EDF + Sbjct: 186 RQQLHLREADREKTRAV-QELSEQNQRLLDQLSRASEVERQLSMQVHALKEDFRE--KNS 242 Query: 211 EDGKLKVTLKYPHYFPLLKKCHVPETRRKV 240 + + L+ + E ++ Sbjct: 243 STNQHIIRLESLQAEIKMLSDRKRELEHRL 272 >2ROH-A nrPDB Length = 122 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 32/79 (40%), Gaps = 6/79 (7%) Query: 467 EVETYFHEFGHVMHQLCSQAEFAMFSGTHVERDFVEAPSQMLENWVWEQEPLLRMSRHYR 526 EVE H+ +F F H R +V+ + W ++ R Sbjct: 38 EVELLVEAVEHLGTGRWRDVKFRAFENVH-HRTYVDLK----DKWKTLVHT-ASIAPQQR 91 Query: 527 TGSAVPRELLEKLIESRQA 545 G+ VP+ELL++++ ++ Sbjct: 92 RGAPVPQELLDRVLAAQAY 110 >2OCP-A nrPDB Length = 241 Score = 29.7 bits (65), Expect = 4.1, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 22/74 (29%), Gaps = 7/74 (9%) Query: 511 WVWEQEPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVL-------AKVDQA 563 W + + +SR P +LL+ + +++ R I + D Sbjct: 70 WSYTFQTFSFLSRLKVQLEPFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIE 129 Query: 564 LHTQTDADPAEEYA 577 H D + Sbjct: 130 WHIYQDWHSFLLWE 143 >2I1J-A nrPDB Length = 575 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 25/163 (15%), Positives = 67/163 (41%), Gaps = 12/163 (7%) Query: 108 FDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARYLERLIKLGRRNGLHLPRETQENIKRI 167 ++ M R+ + ++ + +++ L +A R +L R +E Q+ ++++ Sbjct: 288 HELYMRRRKPDTIDVQQMKAQAREEKLAKQAQREKLQLEIAARERAEKKQQEYQDRLRQM 347 Query: 168 KKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLKYPHYFPL 227 ++++ NL E + ++L L + LE+ ++ + Sbjct: 348 QEEME----RSQANLLEAQDMILRLEEQLRQL-QAAKEELEQRQN-------ELQAMMQR 395 Query: 228 LKKCHVPETRRKVEEAFNCRCKEENCAILKELVTLRAQKSRLL 270 L++ E + + R K+E + +++ V L+ ++R L Sbjct: 396 LEETKNMEAAERQKLEDEIRAKQEEVSRIQQEVELKDSETRRL 438 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.127 0.325 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,022,463 Number of Sequences: 36641 Number of extensions: 923682 Number of successful extensions: 2807 Number of sequences better than 10.0: 32 Number of HSP's better than 10.0 without gapping: 17 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 2721 Number of HSP's gapped (non-prelim): 50 length of query: 689 length of database: 10,336,785 effective HSP length: 104 effective length of query: 585 effective length of database: 6,526,121 effective search space: 3817780785 effective search space used: 3817780785 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 62 (28.6 bits)