BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P52788 (366 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3C6K-A nrPDB 747 0.0 3O4F-A nrPDB 69 5e-12 2O06-A nrPDB 67 1e-11 1MJF-A nrPDB 67 2e-11 2B2C-A nrPDB 65 6e-11 6BQ5-A nrPDB 64 8e-11 1XJ5-A nrPDB 63 2e-10 1UIR-A nrPDB 57 2e-08 1INL-A nrPDB 55 4e-08 4YUX-A nrPDB 53 3e-07 2PT6-A nrPDB 48 6e-06 6QMM-B nrPDB 45 4e-05 1IY9-A nrPDB 43 2e-04 2ZSU-A nrPDB 35 0.069 1XDU-A nrPDB 33 0.14 4JXJ-A nrPDB 32 0.55 1K0F-A nrPDB 32 0.59 1WXW-A nrPDB 32 0.62 1TOA-A nrPDB 32 0.63 5WP4-A nrPDB 29 2.7 5CWV-A nrPDB 29 2.7 6CON-A nrPDB 29 2.8 5YGQ-A nrPDB 29 3.0 3ZM5-A nrPDB 29 3.0 2QM3-A nrPDB 29 3.6 4W6Q-A nrPDB 29 3.7 1HM6-A nrPDB 28 4.7 4L80-A nrPDB 28 5.9 6GWI-A nrPDB 28 6.0 6CLW-A nrPDB 28 6.4 2CMG-A nrPDB 28 9.0 >3C6K-A nrPDB Length = 381 Score = 747 bits (1928), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/364 (99%), Positives = 363/364 (99%) Query: 3 AARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLR 62 +RHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLR Sbjct: 18 GSRHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLR 77 Query: 63 IYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR 122 IYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR Sbjct: 78 IYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR 137 Query: 123 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIM 182 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIM Sbjct: 138 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIM 197 Query: 183 GSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD 242 GSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD Sbjct: 198 GSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD 257 Query: 243 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS 302 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS Sbjct: 258 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS 317 Query: 303 MKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWK 362 MKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWK Sbjct: 318 MKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWK 377 Query: 363 KAKP 366 KAKP Sbjct: 378 KAKP 381 >3O4F-A nrPDB Length = 294 Score = 68.6 bits (166), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 44/148 (29%), Positives = 78/148 (52%), Gaps = 9/148 (6%) Query: 134 YDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGSGKEDYTG-- 191 + +D V+Y E + +Q++ I + FG ++ L G V E D +M G Sbjct: 25 FAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHA 84 Query: 192 KDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K VLI+GGGDG +L E+ + K + +TMVEID V+ C++Y+ D+ + ++ Sbjct: 85 KHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPR---FK 141 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLT 278 ++I+D + + + + FD +I+D T Sbjct: 142 LVIDDGVNFVN---QTSQTFDVIISDCT 166 >2O06-A nrPDB Length = 304 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 58/203 (28%), Positives = 93/203 (45%), Gaps = 29/203 (14%) Query: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIM 182 WP G+ + ++++++ S YQ+I + SK +GN+L+L G + E D +Y I Sbjct: 30 WP---GQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCTERDEFSYQEMIA 86 Query: 183 GSGKEDYTG-KDVLILGGGDGGILCEIVKLKPKMVTMV--EIDQMVIDGCKKYMRKTC-- 237 + + VLI+GGGDGG+L E+VK P + ++V EID+ VI KK++ Sbjct: 87 NLPLCSHPNPRKVLIIGGGDGGVLREVVK-HPSVESVVQCEIDEDVIQVSKKFLPGMAIG 145 Query: 238 --GDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFL 295 L GD ++ + ++ FD +I D S+ P + F Sbjct: 146 YSSSKLTLHVGDGFEFMKQN-----------QDAFDVIITD------SSDPMGPAESLFK 188 Query: 296 RLILDLSMKVLKQDGKYFTQGNC 318 L LK+DG QG C Sbjct: 189 ESYYQLMKTALKEDGVLCCQGEC 211 >1MJF-A nrPDB Length = 281 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 66/218 (30%), Positives = 104/218 (47%), Gaps = 18/218 (8%) Query: 119 AIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAE-SDLAY 177 A ++P G V + I + +Y++ S YQ I++ ++ FG +L L G V L + +Y Sbjct: 4 AFIEWYPRGYG--VAFKIKKKIYEKLSKYQKIEVYETEGFGRLLALDGTVQLVTLGERSY 61 Query: 178 TRAIMGSGKEDYTG-KDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKT 236 ++ + K VL++GGGDGG + E+++ V MVEID+ VI K ++ Sbjct: 62 HEPLVHPAMLAHPKPKRVLVIGGGDGGTVREVLQHDVDEVIMVEIDEDVIMVSKDLIKID 121 Query: 237 CG--DVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEF 294 G + + N K + ++ I D + K R FD +I D T P+ + S EF Sbjct: 122 NGLLEAMLNGKHEKAKLTIGDGF----EFIKNNRGFDVIIADSTD-PVGPAKVLFSE-EF 175 Query: 295 LRLILDLSMKVLKQDGKYFTQGNCVNLT--EALSLYEE 330 R + D L G Y TQ V L E +S Y+E Sbjct: 176 YRYVYD----ALNNPGIYVTQAGSVYLFTDELISAYKE 209 >2B2C-A nrPDB Length = 314 Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 81/262 (30%), Positives = 121/262 (46%), Gaps = 32/262 (12%) Query: 95 ERMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILH 154 E+M S + +V + GGA WP G+ + +V++ E S YQ++ + Sbjct: 18 EKMNGASDEEPTKVLKSDGQEMGGA----WP---GQAFSLQVKKVLFHEKSKYQDVLVFE 70 Query: 155 SKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-GKDVLILGGGDGGILCEIVKLK 212 S +GN+L+L G V E D +Y + + K VLI+GGGDGGIL E++K + Sbjct: 71 STTYGNVLVLDGIVQATERDEFSYQEMLAHLPMFAHPDPKRVLIIGGGDGGILREVLKHE 130 Query: 213 P-KMVTMVEIDQMVIDGCKKYMR-KTCG---DVLDNLKGDCYQVLIEDCIPVLKRYAKEG 267 + VTM EID+MVID KK++ +CG LD GD ++ L Sbjct: 131 SVEKVTMCEIDEMVIDVAKKFLPGMSCGFSHPKLDLFCGDGFEFL-----------KNHK 179 Query: 268 REFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSL 327 EFD +I D S+ P + F + +L LK+DG +QG V L L Sbjct: 180 NEFDVIITD------SSDPVGPAESLFGQSYYELLRDALKEDGILSSQGESVWLHLPLIA 233 Query: 328 YEEQLGRLYCP-VEFSKEIVCV 348 + R P V +++ IV Sbjct: 234 HLVAFNRKIFPAVTYAQSIVST 255 >6BQ5-A nrPDB Length = 331 Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 67/232 (28%), Positives = 111/232 (47%), Gaps = 26/232 (11%) Query: 134 YDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-G 191 + ++ +++ S YQ+I +L +K FG L+L G + AE+D Y ++ + Sbjct: 43 FALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMP 102 Query: 192 KDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K+V I+GGG+G E+++ K V M +ID+ V++ CK Y+ D+ + Sbjct: 103 KNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSR----LE 158 Query: 251 VLIEDCIPVLKRYAKEGRE--FDYVINDLTAVPISTSP-EEDSTWEFLRLILDLSMKVLK 307 V+I D L EG+E +D ++ DL A PI P + T +F L L LK Sbjct: 159 VVINDAKAEL-----EGKEEKYDVIVGDL-ADPIEGGPCYKLYTKDFYELTLKPK---LK 209 Query: 308 QDGKYFTQGNCVNL---TEALSLYEEQLGRLY-CPVEFSKEIVCVPSYLELW 355 + G + TQ + TE S L +++ V +S I PSY ++W Sbjct: 210 KGGIFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHI---PSYADIW 258 >1XJ5-A nrPDB Length = 334 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 53/167 (31%), Positives = 84/167 (50%), Gaps = 13/167 (7%) Query: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIM 182 WP G +++V++ S YQ++ + S +G +L+L G + L E D AY I Sbjct: 55 WP---GEAHSLKVEKVLFQGKSDYQDVIVFQSATYGKVLVLDGVIQLTERDECAYQEMIT 111 Query: 183 GSGKEDYTG-KDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDV 240 K VL++GGGDGG+L E+ + + + M EID+MV+D K++ DV Sbjct: 112 HLPLCSIPNPKKVLVIGGGDGGVLREVARHASIEQIDMCEIDKMVVDVSKQFFP----DV 167 Query: 241 LDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPE 287 + ++I D + LK A EG +D VI D ++ PI + E Sbjct: 168 AIGYEDPRVNLVIGDGVAFLKN-AAEGS-YDAVIVD-SSDPIGPAKE 211 >1UIR-A nrPDB Length = 314 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 50/168 (29%), Positives = 83/168 (49%), Gaps = 12/168 (7%) Query: 136 IDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-GKD 193 ++ V+ +P+Q+ + SK FG +LIL DV E D Y ++ + K Sbjct: 21 MERVIASGKTPFQDYFLFESKGFGKVLILDKDVQSTERDEYIYHETLVHPAMLTHPEPKR 80 Query: 194 VLILGGGDGGILCEIVKLKPKM--VTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQV 251 VLI+GGG+G L E++K P + MV+ID +++ K++M + D+ + + Sbjct: 81 VLIVGGGEGATLREVLK-HPTVEKAVMVDIDGELVEVAKRHMPEWHQGAFDDPRA---VL 136 Query: 252 LIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEE-DSTWEFLRLI 298 +I+D L+R + +D VI DLT +P T EF RL+ Sbjct: 137 VIDDARAYLERTEE---RYDVVIIDLTDPVGEDNPARLLYTVEFYRLV 181 >1INL-A nrPDB Length = 296 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 52/186 (27%), Positives = 86/186 (46%), Gaps = 27/186 (14%) Query: 136 IDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-------LAYTRAIMGSGKED 188 ++ V+Y S Q I I + G + L G E D LA+ + Sbjct: 34 MNRVIYSGQSDIQRIDIFENPDLGVVFALDGITMTTEKDEFMYHEMLAHVPMFLHPNP-- 91 Query: 189 YTGKDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKT-CGDVLDNLKG 246 K VLI+GGGDGG L E++K + + E+D +VI+ +KY+++T CG D+ + Sbjct: 92 ---KKVLIIGGGDGGTLREVLKHDSVEKAILCEVDGLVIEAARKYLKQTSCG--FDDPRA 146 Query: 247 DCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVL 306 +++I + ++++ EFD +I D T P + T EF + D L Sbjct: 147 ---EIVIANGAEYVRKFKN---EFDVIIIDSTD-PTAGQGGHLFTEEFYQACYD----AL 195 Query: 307 KQDGKY 312 K+DG + Sbjct: 196 KEDGVF 201 >4YUX-A nrPDB Length = 304 Score = 52.8 bits (125), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 54/238 (22%), Positives = 110/238 (46%), Gaps = 29/238 (12%) Query: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQ---FGNILILSGDVNLAESDLAYTRA 180 WP G+ + +++V+YD + +Q++ I S +G ++ L G + + + D Sbjct: 27 WP---GQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHE 83 Query: 181 IMGSGK--EDYTGKDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTC 237 ++G + VLI+GGGDGG+L E+++ + +V+ID V++ K++ + Sbjct: 84 VLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQIS 143 Query: 238 GDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRL 297 + D V + D + +++ +D VI D +T P ++ F Sbjct: 144 RSLADPRA----TVRVGDGLAFVRQTPDN--TYDVVIID------TTDPAGPASKLFGEA 191 Query: 298 ILDLSMKVLKQDGKYFTQGNCV----NLTEALSLYEEQLGRLYCPVEFSKEIVCVPSY 351 +++LK DG QG + L E +S + + G + V+++ ++ VP+Y Sbjct: 192 FYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETG--FASVQYA--LMHVPTY 245 >2PT6-A nrPDB Length = 321 Score = 48.1 bits (113), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 45/122 (36%), Positives = 68/122 (55%), Gaps = 13/122 (10%) Query: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAY----T 178 WP G+ I +++Y+ S YQN+ + S +G +L+L G + L E D AY T Sbjct: 51 WP---GQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMT 107 Query: 179 RAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRK-T 236 M KE K+VL++GGGDGGI+ E+ K K + + + EID+ VI+ K Y + + Sbjct: 108 HVPMTVSKEP---KNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNIS 164 Query: 237 CG 238 CG Sbjct: 165 CG 166 >6QMM-B nrPDB Length = 280 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 28/99 (28%), Positives = 57/99 (57%), Gaps = 3/99 (3%) Query: 138 EVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAES-DLAYTRAIMGSGKEDYTG-KDVL 195 +++++E SP+Q I I+ ++ +G L+L AE ++ Y ++ VL Sbjct: 19 QILWEETSPFQKITIVDTEHYGRGLLLDDCWMTAERCEVCYHEYLVHPPLTTAASIARVL 78 Query: 196 ILGGGDGGILCEIVKL-KPKMVTMVEIDQMVIDGCKKYM 233 ++GGGDGG + E+++ + + V +VEID V++ ++Y+ Sbjct: 79 VIGGGDGGTVREVLRYAEVEQVDLVEIDGRVVELSQEYL 117 >1IY9-A nrPDB Length = 275 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 64/236 (27%), Positives = 113/236 (47%), Gaps = 20/236 (8%) Query: 136 IDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYTGKD- 193 +++ ++ E + +Q+++++ +++FGN+L L G V +E D Y + + + Sbjct: 19 VNKTLHTEQTEFQHLEMVETEEFGNMLFLDGMVMTSEKDEFVYHEMVAHVPLFTHPNPEH 78 Query: 194 VLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVL 252 VL++GGGDGG++ EI+K K T+V+ID VI+ KK++ G LD+ + D V Sbjct: 79 VLVVGGGDGGVIREILKHPSVKKATLVDIDGKVIEYSKKFLPSIAGK-LDDPRVD---VQ 134 Query: 253 IEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKY 312 ++D AK ++D ++ D ST P + F + K LK+DG + Sbjct: 135 VDDG---FMHIAKSENQYDVIMVD------STEPVGPAVNLFTKGFYAGIAKALKEDGIF 185 Query: 313 FTQGNCVNLTEALSLYEEQLGRLYCPVE--FSKEIVCVPSYLELWVFYTVWKKAKP 366 Q + T L ++ + P+ ++ I PS LW F KK P Sbjct: 186 VAQTDNPWFTPELITNVQRDVKEIFPITKLYTANIPTYPS--GLWTFTIGSKKYDP 239 >2ZSU-A nrPDB Length = 280 Score = 34.7 bits (78), Expect = 0.069, Method: Compositional matrix adjust. Identities = 58/205 (28%), Positives = 100/205 (48%), Gaps = 19/205 (9%) Query: 123 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNL-AESDLAYTRAI 181 ++P G V + + + +E S YQ I++ ++ FG +L + G V L E + +Y + Sbjct: 9 WYPRGYG--VAFKVKRKILEEQSEYQKIEVYETEGFGKLLAIDGTVQLVTEGEKSYHEPL 66 Query: 182 MGSGKEDYTG-KDVLILGGGDGGILCEIVK-LKPKMVTMVEIDQMVIDGCKKYMRKTCGD 239 + + + VLI+GGGDGG + E++K + + V MVEID+ VI+ KY+ G Sbjct: 67 VHPAMLAHPNPRRVLIIGGGDGGAIREVLKHEEVEEVIMVEIDKKVIEISAKYI-GIDGG 125 Query: 240 VLDNLKGDCYQ---VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLR 296 +L+ + D ++ ++I D + ++ +E FD +I D ST P + F Sbjct: 126 ILEKMLSDKHEKGKLIIGDGV----KFIEENSGFDVIIVD------STDPVGPAEMLFSE 175 Query: 297 LILDLSMKVLKQDGKYFTQGNCVNL 321 + + L G Y TQ V L Sbjct: 176 EFYKNAYRALNDPGIYVTQAGSVYL 200 >1XDU-A nrPDB Length = 374 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 86/213 (40%), Gaps = 46/213 (21%) Query: 164 LSGDVNLAES---------DLAYTRAIMGSGKEDYTG-KDVLILGGGDGGILCEIVKLKP 213 LS DV LA+S DLAY + D++ + VL +GGG+GG+L I P Sbjct: 149 LSADVALADSFDALMSCDEDLAYEAP---ADAYDWSAVRHVLDVGGGNGGMLAAIALRAP 205 Query: 214 KMV-TMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLI-----------------ED 255 + T+VE+ +++ D + +GD ++ L ED Sbjct: 206 HLRGTLVELAGPAERARRRFADAGLADRVTVAEGDFFKPLPVTADVVLLSFVLLNWSDED 265 Query: 256 CIPVLK---RYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKY 312 + +L+ R + G ++ D V E D F +LDL M G+ Sbjct: 266 ALTILRGCVRALEPGGRL--LVLDRADV------EGDGADRFFSTLLDLRMLTF-MGGRV 316 Query: 313 FTQGNCVNL--TEALSLYEEQL-GRLYCPVEFS 342 T+ V+L + L+L E+ G P +FS Sbjct: 317 RTRDEVVDLAGSAGLALASERTSGSTTLPFDFS 349 >4JXJ-A nrPDB Length = 276 Score = 31.6 bits (70), Expect = 0.55, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 179 RAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVI 226 + + SG E+ +VL +G G GG+ I+ PK++T++E D+ I Sbjct: 41 KIVRASGLEE--NSNVLEIGPGTGGLTRSILHKNPKLLTVIETDERCI 86 >1K0F-A nrPDB Length = 277 Score = 31.6 bits (70), Expect = 0.59, Method: Compositional matrix adjust. Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 28/107 (26%) Query: 169 NLAESDLAYTRAIMGSGKEDY----TGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQM 224 N+A+ D+ + + +MG G + + T DV LG D IL + L+ KM Sbjct: 18 NIAQGDV-HLKGLMGPGVDPHLYTATAGDVEWLGNADL-ILYNGLHLETKM--------- 66 Query: 225 VIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFD 271 G+V L+G V + + IPV +R + E EFD Sbjct: 67 -------------GEVFSKLRGSRLVVAVSETIPVSQRLSLEEAEFD 100 >1WXW-A nrPDB Length = 382 Score = 31.6 bits (70), Expect = 0.62, Method: Compositional matrix adjust. Identities = 26/102 (25%), Positives = 47/102 (46%), Gaps = 2/102 (1%) Query: 224 MVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPIS 283 + +D + +R+ + N G+ +VL + +L+R KEG FD V+ D A Sbjct: 235 VAVDSSAEALRRAEENARLNGLGNV-RVLEANAFDLLRRLEKEGERFDLVVLDPPAFAKG 293 Query: 284 TSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEAL 325 E + + + L ++K+LK+ G T ++TE L Sbjct: 294 KKDVERAYRAYKEVNLR-AIKLLKEGGILATASCSHHMTEPL 334 >1TOA-A nrPDB Length = 313 Score = 31.6 bits (70), Expect = 0.63, Method: Compositional matrix adjust. Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 28/107 (26%) Query: 169 NLAESDLAYTRAIMGSGKEDY----TGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQM 224 N+A+ D+ + + +MG G + + T DV LG D IL + L+ KM Sbjct: 54 NIAQGDV-HLKGLMGPGVDPHLYTATAGDVEWLGNADL-ILYNGLHLETKM--------- 102 Query: 225 VIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFD 271 G+V L+G V + + IPV +R + E EFD Sbjct: 103 -------------GEVFSKLRGSRLVVAVSETIPVSQRLSLEEAEFD 136 >5WP4-A nrPDB Length = 491 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 5/57 (8%) Query: 189 YTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMV-----IDGCKKYMRKTCGDV 240 Y GK VL LG G G E+ + +++ + ID ++ I+G K ++ C DV Sbjct: 52 YEGKSVLELGAGIGRFTGELAQKAGELIALDFIDNVIKKNESINGHYKNVKFMCADV 108 >5CWV-A nrPDB Length = 364 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 251 VLIEDCIPVLKRYAKEGREFDYVI--NDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQ 308 VL++ +L + FD + N ++PI SP + T L L+L L +Q Sbjct: 142 VLVDSLKEILNEWLAPSSTFDPSLSTNASPSLPIPASPSQQYTSAKLALLLQLCQT--RQ 199 Query: 309 DGKYFTQGN 317 KY Q N Sbjct: 200 GAKYVLQAN 208 >6CON-A nrPDB Length = 305 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 175 LAYTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEID 222 +A+ RAI+ + D T V+ GG D G+LC K+K V +D Sbjct: 46 MAFVRAIL---RSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLD 90 >5YGQ-A nrPDB Length = 342 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 11/18 (61%), Positives = 15/18 (83%) Query: 187 EDYTGKDVLILGGGDGGI 204 ED+ GKD+LI+GGGD + Sbjct: 150 EDFRGKDILIVGGGDSAL 167 >3ZM5-A nrPDB Length = 465 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 52/205 (25%), Positives = 81/205 (39%), Gaps = 40/205 (19%) Query: 172 ESDLAYTRAIMGSGKEDYT---GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDG 228 E L YT M G E G+D L GD +L E+ + K +VT+V + Sbjct: 138 EIGLPYTVLHMPEGTEKLVLEMGQDHL----GDIHLLSELARPKTAIVTLVGEAHLAFFK 193 Query: 229 CKKYMRKTCGDVLDNLKGDCYQV-----LIEDCIPVLKRYAKEGREFDYVINDLTAVPIS 283 + + K + D + + ++ED +P+ K+ + G+ + I DL S Sbjct: 194 DRSEIAKGKMQIADGMASGSLLLAPADPIVEDYLPIDKKVVRFGQGAELEITDLVERKDS 253 Query: 284 TSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQ----GNCVNLTEALSLYEEQLGRLYCPV 339 + + + FL LDL + GKY + V L E +S EEQ+ + Sbjct: 254 LTFKAN----FLEQALDLPVT-----GKYNATNAMIASYVALQEGVS--EEQIRLAF--- 299 Query: 340 EFSKEIVCVPSYLELWVFYTVWKKA 364 +LEL T WKKA Sbjct: 300 ----------QHLELTRNRTEWKKA 314 >2QM3-A nrPDB Length = 373 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 25/113 (22%), Positives = 49/113 (43%), Gaps = 17/113 (15%) Query: 141 YDEDSPYQNIKILHSKQFGNILILSGDV------NLAESDLAY-------TRAIMGSGKE 187 YD P+ K + + F ++L ++ L E D AY R I+ + Sbjct: 110 YDFTCPHCQGKTVDLQAFADLLEQFREIVKDRPEPLHEFDQAYVTPETTVARVILMHTRG 169 Query: 188 DYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDV 240 D KD+ +LG D + ++ PK + +++ID+ + K++ K ++ Sbjct: 170 DLENKDIFVLGDDDLTSIALMLSGLPKRIAVLDIDERL----TKFIEKAANEI 218 >4W6Q-A nrPDB Length = 333 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 20/39 (51%) Query: 84 EEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR 122 E+ID I N VE +E + V+R P+VR G R Sbjct: 281 EKIDDISNIVESTTEEEYMEIVSDVRRFNPLVRQGYFTR 319 >1HM6-A nrPDB Length = 346 Score = 28.5 bits (62), Expect = 4.7, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 215 MVTMVEIDQMVIDGC--KKYMRKTCGDVLDNLKGDCYQVLIEDC 256 MV+ EID I C K Y C +LD KGD ++L+ C Sbjct: 300 MVSRSEIDMNDIKACYQKLYGISLCQAILDETKGDYEKILVALC 343 >4L80-A nrPDB Length = 348 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 35/66 (53%), Gaps = 8/66 (12%) Query: 252 LIEDCIPVLKR-YAKEGREFDYVINDLTAVP-------ISTSPEEDSTWEFLRLILDLSM 303 L + IP+ KR ++ + E + L A+P I ++D+TW+ ++I+DL+ Sbjct: 274 LAPNQIPIAKRVFSPDVNEVLFAKRILEAMPDGSGVAMIDGKMQDDATWKQAKVIVDLAR 333 Query: 304 KVLKQD 309 + K+D Sbjct: 334 MIAKKD 339 >6GWI-A nrPDB Length = 462 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%) Query: 93 VEERMKELSQDSTGRVKRLPPIVRGGAI---DRYWPTADGRLVEYDI----DEVV 140 +EE++ EL ++ P GGAI + YWP L +YDI DEV+ Sbjct: 205 LEEKILELGEEKVAAFIAEPVQGAGGAIMPPESYWPAVKKVLAKYDILLVADEVI 259 >6CLW-A nrPDB Length = 364 Score = 28.1 bits (61), Expect = 6.4, Method: Compositional matrix adjust. Identities = 9/24 (37%), Positives = 18/24 (75%) Query: 192 KDVLILGGGDGGILCEIVKLKPKM 215 + V+ +GGG GG+L E+++ +P + Sbjct: 191 RHVMDVGGGTGGVLAEVLRARPGL 214 >2CMG-A nrPDB Length = 262 Score = 27.7 bits (60), Expect = 9.0, Method: Compositional matrix adjust. Identities = 25/99 (25%), Positives = 47/99 (47%), Gaps = 6/99 (6%) Query: 133 EYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDV---NLAESDLAYTRAIMGSGKEDY 189 EY I+ + D S + ++I SK FG I +L+ + N + + G K++ Sbjct: 14 EYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNRQLLFKNFLHIESELLAHMGGCTKKEL 73 Query: 190 TGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDG 228 K+VLI+ G D + ++ K + V+ D+ ++D Sbjct: 74 --KEVLIVDGFDLELAHQLFKYDTH-IDFVQADEKILDS 109 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3C6K-A nrPDB 584 e-167 2B2C-A nrPDB 263 9e-71 4YUX-A nrPDB 238 3e-63 2O06-A nrPDB 236 8e-63 1XJ5-A nrPDB 224 4e-59 1IY9-A nrPDB 221 3e-58 1MJF-A nrPDB 220 6e-58 6BQ5-A nrPDB 219 2e-57 3O4F-A nrPDB 212 2e-55 1INL-A nrPDB 210 8e-55 1UIR-A nrPDB 195 2e-50 6QMM-B nrPDB 182 3e-46 2PT6-A nrPDB 178 3e-45 Sequences not found previously or not previously below threshold: 2ZSU-A nrPDB 164 4e-41 2CMG-A nrPDB 49 2e-06 1WXW-A nrPDB 39 0.003 3C0K-A nrPDB 38 0.006 3LDF-A nrPDB 37 0.016 3CCF-A nrPDB 36 0.024 4JXJ-A nrPDB 35 0.036 3IWA-A nrPDB 35 0.036 1KYQ-A nrPDB 33 0.21 5JE5-A nrPDB 33 0.24 2IFT-A nrPDB 32 0.50 3R9X-B nrPDB 32 0.54 1J93-A nrPDB 32 0.57 6MRO-A nrPDB 31 0.76 2PJD-A nrPDB 31 0.90 6CLW-A nrPDB 31 0.91 5BP7-A nrPDB 30 1.2 2PXX-A nrPDB 30 1.9 3ORF-A nrPDB 29 2.4 5XNC-A nrPDB 29 2.9 3QWB-A nrPDB 29 3.8 5DXF-A nrPDB 29 4.8 3L82-B nrPDB 27 9.3 3L2O-B nrPDB 27 9.3 >3C6K-A nrPDB Length = 381 Score = 584 bits (1505), Expect = e-167, Method: Composition-based stats. Identities = 362/364 (99%), Positives = 363/364 (99%) Query: 3 AARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLR 62 +RHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLR Sbjct: 18 GSRHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANLR 77 Query: 63 IYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR 122 IYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR Sbjct: 78 IYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDR 137 Query: 123 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIM 182 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIM Sbjct: 138 YWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIM 197 Query: 183 GSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD 242 GSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD Sbjct: 198 GSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD 257 Query: 243 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS 302 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS Sbjct: 258 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS 317 Query: 303 MKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWK 362 MKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWK Sbjct: 318 MKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWK 377 Query: 363 KAKP 366 KAKP Sbjct: 378 KAKP 381 >2B2C-A nrPDB Length = 314 Score = 263 bits (672), Expect = 9e-71, Method: Composition-based stats. Identities = 79/261 (30%), Positives = 117/261 (44%), Gaps = 25/261 (9%) Query: 95 ERMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILH 154 E+M S + +V + GGA WP G+ + +V++ E S YQ++ + Sbjct: 18 EKMNGASDEEPTKVLKSDGQEMGGA----WP---GQAFSLQVKKVLFHEKSKYQDVLVFE 70 Query: 155 SKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-GKDVLILGGGDGGILCEIVKLK 212 S +GN+L+L G V E D +Y + + K VLI+GGGDGGIL E++K + Sbjct: 71 STTYGNVLVLDGIVQATERDEFSYQEMLAHLPMFAHPDPKRVLIIGGGDGGILREVLKHE 130 Query: 213 P-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFD 271 + VTM EID+MVID KK++ + D LK EFD Sbjct: 131 SVEKVTMCEIDEMVIDVAKKFLPGMSCGF----SHPKLDLFCGDGFEFLK---NHKNEFD 183 Query: 272 YVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQ 331 +I D S+ P + F + +L LK+DG +QG V L L + Sbjct: 184 VIITD------SSDPVGPAESLFGQSYYELLRDALKEDGILSSQGESVWLHLPLIAHLVA 237 Query: 332 LGRLYCP-VEFSKEIV-CVPS 350 R P V +++ IV PS Sbjct: 238 FNRKIFPAVTYAQSIVSTYPS 258 >4YUX-A nrPDB Length = 304 Score = 238 bits (607), Expect = 3e-63, Method: Composition-based stats. Identities = 55/253 (21%), Positives = 113/253 (44%), Gaps = 28/253 (11%) Query: 111 LPPIVR--GGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQ---FGNILILS 165 +P GG G+ + +++V+YD + +Q++ I S +G ++ L Sbjct: 9 MPGSELISGGWFREENDQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALD 68 Query: 166 GDVNLAESD-LAYTRAIMGSGKEDYT-GKDVLILGGGDGGILCEIVKLKP-KMVTMVEID 222 G + + + D Y + + + + VLI+GGGDGG+L E+++ + +V+ID Sbjct: 69 GCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDID 128 Query: 223 QMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPI 282 V++ K++ + + D V + D + +++ +D VI D Sbjct: 129 GEVMEQSKQHFPQISRSLADPR----ATVRVGDGLAFVRQTPDN--TYDVVIID------ 176 Query: 283 STSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVN----LTEALSLYEEQLGRLYCP 338 +T P ++ F +++LK DG QG + L E +S + + G + Sbjct: 177 TTDPAGPASKLFGEAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRETG--FAS 234 Query: 339 VEFSKEIVCVPSY 351 V+++ ++ VP+Y Sbjct: 235 VQYA--LMHVPTY 245 >2O06-A nrPDB Length = 304 Score = 236 bits (603), Expect = 8e-63, Method: Composition-based stats. Identities = 65/244 (26%), Positives = 102/244 (41%), Gaps = 18/244 (7%) Query: 112 PPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLA 171 P +R G G+ + ++++++ S YQ+I + SK +GN+L+L G + Sbjct: 15 PAAIREGWFRETCSLWPGQALSLQVEQLLHHRRSRYQDILVFRSKTYGNVLVLDGVIQCT 74 Query: 172 ESD-LAYTRAIMGSGKEDYT-GKDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDG 228 E D +Y I + + VLI+GGGDGG+L E+VK + V EID+ VI Sbjct: 75 ERDEFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVVKHPSVESVVQCEIDEDVIQV 134 Query: 229 CKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEE 288 KK++ + + + D +K+ FD +I D S+ P Sbjct: 135 SKKFLP----GMAIGYSSSKLTLHVGDGFEFMKQ---NQDAFDVIITD------SSDPMG 181 Query: 289 DSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCP-VEFS-KEIV 346 + F L LK+DG QG C L L Q + P V ++ I Sbjct: 182 PAESLFKESYYQLMKTALKEDGVLCCQGECQWLHLDLIKEMRQFCQSLFPVVAYAYCTIP 241 Query: 347 CVPS 350 PS Sbjct: 242 TYPS 245 >1XJ5-A nrPDB Length = 334 Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 65/274 (23%), Positives = 108/274 (39%), Gaps = 22/274 (8%) Query: 83 KEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYD 142 +EE D+ E + + P G P G +++V++ Sbjct: 15 REEDDNGGAATMETENGDQKKEPACFSTVIP----GWFSEMSPMWPGEAHSLKVEKVLFQ 70 Query: 143 EDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-GKDVLILGGG 200 S YQ++ + S +G +L+L G + L E D AY I K VL++GGG Sbjct: 71 GKSDYQDVIVFQSATYGKVLVLDGVIQLTERDECAYQEMITHLPLCSIPNPKKVLVIGGG 130 Query: 201 DGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPV 259 DGG+L E+ + + + M EID+MV+D K++ DV + ++I D + Sbjct: 131 DGGVLREVARHASIEQIDMCEIDKMVVDVSKQFFP----DVAIGYEDPRVNLVIGDGVAF 186 Query: 260 LKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCV 319 LK A+ +D VI D S+ P + F + + L+ G TQ + Sbjct: 187 LKNAAEGS--YDAVIVD------SSDPIGPAKELFEKPFFQSVARALRPGGVVCTQAESL 238 Query: 320 NLTEALSLYEEQLGRLYC--PVEFS-KEIVCVPS 350 L + R V ++ + PS Sbjct: 239 WLHMDIIEDIVSNCREIFKGSVNYAWTSVPTYPS 272 >1IY9-A nrPDB Length = 275 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 64/240 (26%), Positives = 114/240 (47%), Gaps = 20/240 (8%) Query: 132 VEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT 190 + +++ ++ E + +Q+++++ +++FGN+L L G V +E D Y + + Sbjct: 15 ITMKVNKTLHTEQTEFQHLEMVETEEFGNMLFLDGMVMTSEKDEFVYHEMVAHVPLFTHP 74 Query: 191 -GKDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDC 248 + VL++GGGDGG++ EI+K K T+V+ID VI+ KK++ G LD+ + D Sbjct: 75 NPEHVLVVGGGDGGVIREILKHPSVKKATLVDIDGKVIEYSKKFLPSIAG-KLDDPRVD- 132 Query: 249 YQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQ 308 V ++D AK ++D ++ D ST P + F + K LK+ Sbjct: 133 --VQVDDG---FMHIAKSENQYDVIMVD------STEPVGPAVNLFTKGFYAGIAKALKE 181 Query: 309 DGKYFTQGNCVNLTEALSLYEEQLGRLYCPVE--FSKEIVCVPSYLELWVFYTVWKKAKP 366 DG + Q + T L ++ + P+ ++ I PS LW F KK P Sbjct: 182 DGIFVAQTDNPWFTPELITNVQRDVKEIFPITKLYTANIPTYPS--GLWTFTIGSKKYDP 239 >1MJF-A nrPDB Length = 281 Score = 220 bits (561), Expect = 6e-58, Method: Composition-based stats. Identities = 67/249 (26%), Positives = 109/249 (43%), Gaps = 19/249 (7%) Query: 119 AIDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAE-SDLAY 177 A ++P G V + I + +Y++ S YQ I++ ++ FG +L L G V L + +Y Sbjct: 4 AFIEWYPRGYG--VAFKIKKKIYEKLSKYQKIEVYETEGFGRLLALDGTVQLVTLGERSY 61 Query: 178 TRAIMGSGKEDYT-GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKT 236 ++ + K VL++GGGDGG + E+++ V MVEID+ VI K ++ Sbjct: 62 HEPLVHPAMLAHPKPKRVLVIGGGDGGTVREVLQHDVDEVIMVEIDEDVIMVSKDLIKID 121 Query: 237 CG--DVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEF 294 G + + N K + ++ I D + K R FD +I D ST P + F Sbjct: 122 NGLLEAMLNGKHEKAKLTIGDGFEFI----KNNRGFDVIIAD------STDPVGPAKVLF 171 Query: 295 LRLILDLSMKVLKQDGKYFTQGNCVNL-TEALSLYEEQLGRLYCPVEFSKEIVCVPSYLE 353 L G Y TQ V L T+ L +++ +++ V + V Y Sbjct: 172 SEEFYRYVYDALNNPGIYVTQAGSVYLFTDELISAYKEMKKVFDRVYYYS--FPVIGYAS 229 Query: 354 LWVFYTVWK 362 W F K Sbjct: 230 PWAFLVGVK 238 >6BQ5-A nrPDB Length = 331 Score = 219 bits (557), Expect = 2e-57, Method: Composition-based stats. Identities = 60/235 (25%), Positives = 107/235 (45%), Gaps = 20/235 (8%) Query: 134 YDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-G 191 + ++ +++ S YQ+I +L +K FG L+L G + AE+D Y ++ + Sbjct: 43 FALNSILHTGASQYQDIALLDTKPFGKALVLDGKLQSAETDEFIYHECLVHPALLHHPMP 102 Query: 192 KDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K+V I+GGG+G E+++ K V M +ID+ V++ CK Y+ D+ + Sbjct: 103 KNVFIMGGGEGSTARELLRHKTIDKVVMCDIDEEVVEFCKSYLVVNKEAFHDSR----LE 158 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDG 310 V+I D L+ + ++D ++ DL + T +F L L LK+ G Sbjct: 159 VVINDAKAELE---GKEEKYDVIVGDLADPIEGGPCYKLYTKDFYELTLKPK---LKKGG 212 Query: 311 KYFTQGNCVNL---TEALSLYEEQLGRLY-CPVEFSKEIVCVPSYLELWVFYTVW 361 + TQ + TE S L +++ V +S I PSY ++W + Sbjct: 213 IFVTQAGPAGIFSHTEVFSCIYNTLRQVFKYVVPYSAHI---PSYADIWGWVLAS 264 >3O4F-A nrPDB Length = 294 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 55/229 (24%), Positives = 97/229 (42%), Gaps = 19/229 (8%) Query: 134 YDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDY-TG 191 + +D V+Y E + +Q++ I + FG ++ L G V E D Y + + Sbjct: 25 FAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHA 84 Query: 192 KDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K VLI+GGGDG +L E+ + K + +TMVEID V+ C++Y+ D+ + ++ Sbjct: 85 KHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPR---FK 141 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDG 310 ++I+D + + + + FD +I+D T P F + + L G Sbjct: 142 LVIDDGVNFVNQT---SQTFDVIISDCTD------PIGPGESLFTSAFYEGCKRCLNPGG 192 Query: 311 KYFTQGNCVNL-TEALSLYEEQLGRLYCPVE-FSKEIVCVPSYLELWVF 357 + Q L E +L + V + I Y + F Sbjct: 193 IFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTY--YGGIMTF 239 >1INL-A nrPDB Length = 296 Score = 210 bits (534), Expect = 8e-55, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 96/238 (40%), Gaps = 19/238 (7%) Query: 134 YDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-G 191 ++ V+Y S Q I I + G + L G E D Y + + Sbjct: 32 MKMNRVIYSGQSDIQRIDIFENPDLGVVFALDGITMTTEKDEFMYHEMLAHVPMFLHPNP 91 Query: 192 KDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K VLI+GGGDGG L E++K + + E+D +VI+ +KY+++T D+ + + Sbjct: 92 KKVLIIGGGDGGTLREVLKHDSVEKAILCEVDGLVIEAARKYLKQTSCG-FDDPRA---E 147 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDG 310 ++I + ++++ EFD +I D T P + T EF + D LK+DG Sbjct: 148 IVIANGAEYVRKFKN---EFDVIIIDSTD-PTAGQGGHLFTEEFYQACYD----ALKEDG 199 Query: 311 KYFTQGNCVNLTEALSLYEEQLGRLYCPVE--FSKEIVCVPSYLELWVFYTVWKKAKP 366 + + + P+ + + PS +W + K P Sbjct: 200 VFSAETEDPFYDIGWFKLAYRRISKVFPITRVYLGFMTTYPS--GMWSYTFASKGIDP 255 >1UIR-A nrPDB Length = 314 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 59/238 (24%), Positives = 99/238 (41%), Gaps = 18/238 (7%) Query: 135 DIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIMGSGKEDYT-GK 192 ++ V+ +P+Q+ + SK FG +LIL DV E D Y ++ + K Sbjct: 20 RMERVIASGKTPFQDYFLFESKGFGKVLILDKDVQSTERDEYIYHETLVHPAMLTHPEPK 79 Query: 193 DVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQV 251 VLI+GGG+G L E++K + MV+ID +++ K++M + D+ + + Sbjct: 80 RVLIVGGGEGATLREVLKHPTVEKAVMVDIDGELVEVAKRHMPEWHQGAFDDPRA---VL 136 Query: 252 LIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEE-DSTWEFLRLILDLSMKVLKQDG 310 +I+D L+R + +D VI DLT +P T EF RL+ L G Sbjct: 137 VIDDARAYLERTEE---RYDVVIIDLTDPVGEDNPARLLYTVEFYRLV----KAHLNPGG 189 Query: 311 KYFTQGNCVNLT--EALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVWKKAKP 366 Q + LT + + + V K +P + + F P Sbjct: 190 VMGMQTGMILLTHHRVHPVVHRTVREAFRYVRSYKN--HIPGFFLNFGFLLASDAFDP 245 >6QMM-B nrPDB Length = 280 Score = 182 bits (461), Expect = 3e-46, Method: Composition-based stats. Identities = 50/225 (22%), Positives = 98/225 (43%), Gaps = 17/225 (7%) Query: 138 EVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAES-DLAYTRAIMGSGKEDYTG-KDVL 195 +++++E SP+Q I I+ ++ +G L+L AE ++ Y ++ VL Sbjct: 19 QILWEETSPFQKITIVDTEHYGRGLLLDDCWMTAERCEVCYHEYLVHPPLTTAASIARVL 78 Query: 196 ILGGGDGGILCEIVKL-KPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIE 254 ++GGGDGG + E+++ + + V +VEID V++ ++Y+ D V I Sbjct: 79 VIGGGDGGTVREVLRYAEVEQVDLVEIDGRVVELSQEYLGAIGTAWADPR----LNVKIG 134 Query: 255 DCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFT 314 D I ++ +D ++ D + P + F R + +VLK G + + Sbjct: 135 DGIAFVQTAPDAS--YDVILVD------GSDPAGPAAGLFNREFYENCRRVLKPGGVFAS 186 Query: 315 QGNCVNLTEALSL-YEEQLGRLYCPV-EFSKEIVCVPSYLELWVF 357 Q + A+ L E L ++ + + PS W++ Sbjct: 187 QAESPDSFLAVHLEMIETLSAVFAEAKPYYGWVPMYPSGWWSWLY 231 >2PT6-A nrPDB Length = 321 Score = 178 bits (452), Expect = 3e-45, Method: Composition-based stats. Identities = 58/231 (25%), Positives = 95/231 (41%), Gaps = 21/231 (9%) Query: 124 WPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESD-LAYTRAIM 182 WP G+ I +++Y+ S YQN+ + S +G +L+L G + L E D AY + Sbjct: 51 WP---GQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDGVIQLTEKDEFAYHEMMT 107 Query: 183 GSGKE-DYTGKDVLILGGGDGGILCEIVKLKP-KMVTMVEIDQMVIDGCKKYMRKTCGDV 240 K+VL++GGGDGGI+ E+ K K + + + EID+ VI+ K Y + Sbjct: 108 HVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSVENIDICEIDETVIEVSKIYFKNISCG- 166 Query: 241 LDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILD 300 + V IED L+ +D +I D S+ P + F + + Sbjct: 167 ---YEDKRVNVFIEDASKFLENVT---NTYDVIIVD------SSDPIGPAETLFNQNFYE 214 Query: 301 LSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYC-PVEFSK-EIVCVP 349 LK +G Q + + + VE++ I P Sbjct: 215 KIYNALKPNGYCVAQCESLWIHVGTIKNMIGYAKKLFKKVEYANISIPTYP 265 >2ZSU-A nrPDB Length = 280 Score = 164 bits (416), Expect = 4e-41, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 112/249 (44%), Gaps = 20/249 (8%) Query: 120 IDRYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNL-AESDLAYT 178 ++P G V + + + +E S YQ I++ ++ FG +L + G V L E + +Y Sbjct: 6 FIEWYPRGYG--VAFKVKRKILEEQSEYQKIEVYETEGFGKLLAIDGTVQLVTEGEKSYH 63 Query: 179 RAIMGSGKEDYT-GKDVLILGGGDGGILCEIVKL-KPKMVTMVEIDQMVIDGCKKYMRKT 236 ++ + + VLI+GGGDGG + E++K + + V MVEID+ VI+ KY+ Sbjct: 64 EPLVHPAMLAHPNPRRVLIIGGGDGGAIREVLKHEEVEEVIMVEIDKKVIEISAKYIGID 123 Query: 237 CG--DVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEF 294 G + + + K + +++I D + + +E FD +I D ST P + F Sbjct: 124 GGILEKMLSDKHEKGKLIIGDGVKFI----EENSGFDVIIVD------STDPVGPAEMLF 173 Query: 295 LRLILDLSMKVLKQDGKYFTQGNCVNL-TEALSLYEEQLGRLYCPVEFSKEIVCVPSYLE 353 + + L G Y TQ V L T+ ++ +++ V + V Y Sbjct: 174 SEEFYKNAYRALNDPGIYVTQAGSVYLFTDEFLTAYRKMRKVFDKVYYYS--FPVIGYAS 231 Query: 354 LWVFYTVWK 362 W F K Sbjct: 232 PWAFLVGVK 240 >2CMG-A nrPDB Length = 262 Score = 49.3 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 69/192 (35%), Gaps = 32/192 (16%) Query: 133 EYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAY--TRAIMGSGKEDYT 190 EY I+ + D S + ++I SK FG I +L+ L + + + + G Sbjct: 14 EYTIEAKLLDVRSEHNILEIFKSKDFGEIAMLNR--QLLFKNFLHIESELLAHMGGCTKK 71 Query: 191 G-KDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCY 249 K+VLI+ G D + ++ K + V+ D+ ++D + Sbjct: 72 ELKEVLIVDGFDLELAHQLFKYDT-HIDFVQADEKILDSFISFFPHFHE----------- 119 Query: 250 QVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQD 309 +++ +AK+ + D DL +D ++LK+D Sbjct: 120 ---VKNNKNF--THAKQLLDLDIKKYDLIFCLQEPDIHR----------IDGLKRMLKED 164 Query: 310 GKYFTQGNCVNL 321 G + + L Sbjct: 165 GVFISVAKHPLL 176 >1WXW-A nrPDB Length = 382 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 46/103 (44%), Gaps = 8/103 (7%) Query: 226 IDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTS 285 +D + +R+ + N G+ +VL + +L+R KEG FD V+ D P + + Sbjct: 237 VDSSAEALRRAEENARLNGLGN-VRVLEANAFDLLRRLEKEGERFDLVVLD----PPAFA 291 Query: 286 PEEDSTWEFLRLILDLSMKV---LKQDGKYFTQGNCVNLTEAL 325 + R +++++ LK+ G T ++TE L Sbjct: 292 KGKKDVERAYRAYKEVNLRAIKLLKEGGILATASCSHHMTEPL 334 >3C0K-A nrPDB Length = 396 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 45/124 (36%), Gaps = 7/124 (5%) Query: 191 GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K VL GG + V V+ Q +D ++ + D+ + Sbjct: 221 NKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDL------SKAE 274 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDG 310 + +D +L+ Y G +FD ++ D + + + I L++++L + G Sbjct: 275 FVRDDVFKLLRTYRDRGEKFDVIVMDPPKF-VENKSQLMGACRGYKDINMLAIQLLNEGG 333 Query: 311 KYFT 314 T Sbjct: 334 ILLT 337 >3LDF-A nrPDB Length = 385 Score = 36.6 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 250 QVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQD 309 Q+++ D K + +D +I D + + + ++ +LI +++L ++ Sbjct: 266 QLVVMDVFDYFKYARRHHLTYDIIIIDPPSFARNKKEVFSVSKDYHKLIRQG-LEILSEN 324 Query: 310 GKYFTQGNCVNLTEALSLYEEQLGRLY 336 G N N+T +S +++Q+ + + Sbjct: 325 GLIIASTNAANMT--VSQFKKQIEKGF 349 >3CCF-A nrPDB Length = 279 Score = 36.2 bits (82), Expect = 0.024, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 54/172 (31%), Gaps = 13/172 (7%) Query: 177 YTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKT 236 Y ++ G+ +L LG G G + +I + + V + +I+ ++ Sbjct: 45 YGEDLLQL-LNPQPGEFILDLGCGTGQLTEKIAQSGAE-VLGTDNAATMIEKARQNYPHL 102 Query: 237 CGDVLDNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFL- 295 DV D ++V +E + I + S EF Sbjct: 103 HFDVADAR---NFRVDKPLDAVFSNAMLHWVKEPEAAIASIHQALKSG---GRFVAEFGG 156 Query: 296 ----RLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSK 343 + IL+ L+ G + Q ++ Y L + V ++ Sbjct: 157 KGNIKYILEALYNALETLGIHNPQALNPWYFPSIGEYVNILEKQGFDVTYAA 208 >4JXJ-A nrPDB Length = 276 Score = 35.5 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 3/58 (5%) Query: 191 GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDG---CKKYMRKTCGDVLDNLK 245 +VL +G G GG+ I+ PK++T++E D+ I K+Y D LK Sbjct: 51 NSNVLEIGPGTGGLTRSILHKNPKLLTVIETDERCIPLLNEIKQYHPNLNIIKQDALK 108 >3IWA-A nrPDB Length = 472 Score = 35.5 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 46/138 (33%), Gaps = 14/138 (10%) Query: 162 LILSGDVNLAESDLAYTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEI 221 + L+G + D A + +I+GGG G +++ + M I Sbjct: 133 MDLAGVTPVTNLDEA---EFVQHAISAGEVSKAVIVGGGFIG-----LEMAVSLADMWGI 184 Query: 222 DQMVIDGCKKYMRKTCGDVLDN---LKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLT 278 D V++ + M L + V++ V++ + G+ + + T Sbjct: 185 DTTVVELADQIMPGFTSKSLSQMLRHDLEKNDVVVHTGEKVVRLEGENGKVARVITDKRT 244 Query: 279 ---AVPISTSPEEDSTWE 293 + I + +T Sbjct: 245 LDADLVILAAGVSPNTQL 262 >1KYQ-A nrPDB Length = 274 Score = 33.1 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 47/134 (35%), Gaps = 19/134 (14%) Query: 192 KDVLILGGGDGGILCEIVKLKPK--MVTMV--EIDQMVIDGCKKYMRKTCGDVL------ 241 K +L++GGG+ G+ + KL P +T+V ++ + +I K+++ Sbjct: 14 KRILLIGGGEVGLTR-LYKLMPTGCKLTLVSPDLHKSIIPKFGKFIQNKDQPDYREDAKR 72 Query: 242 ------DNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFL 295 D K + Y+ + D E + ++ + P S F Sbjct: 73 FINPNWDPTKNEIYEYIRSDFKDEYLDLENENDAWYIIMTCIPDHPESARIYHLCKERFG 132 Query: 296 RLILDLSMKVLKQD 309 + L K D Sbjct: 133 KQ--QLVNVADKPD 144 >5JE5-A nrPDB Length = 247 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 31/142 (21%), Positives = 49/142 (34%), Gaps = 37/142 (26%) Query: 191 GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 GK VL L G G EI + V V+I + +I+ ++ RK GD + Sbjct: 42 GKSVLDLACGFGFFGREIYRRGAAKVVGVDISEKMIELAREESRKY---------GDPLE 92 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEF--------LRLILDLS 302 + D + + +FD V ++ W F LR + + Sbjct: 93 FHVRDVANM-----EPLGQFDLV---------------NAAWLFNYADSVENLRKMFKVV 132 Query: 303 MKVLKQDGKYFTQGNCVNLTEA 324 LK DGK + + A Sbjct: 133 RASLKPDGKLVAYTVDPDFSLA 154 >2IFT-A nrPDB Length = 201 Score = 31.6 bits (70), Expect = 0.50, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Query: 200 GDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPV 259 G G + E + + K VT +E+D+ V + KK ++ + +V+ + + Sbjct: 63 GSGSLGFEALSRQAKKVTFLELDKTVANQLKKNLQTLKCSS------EQAEVINQSSLDF 116 Query: 260 LKRYAKEGREFDYVIND 276 LK+ + FD V D Sbjct: 117 LKQ-PQNQPHFDVVFLD 132 >3R9X-B nrPDB Length = 248 Score = 31.6 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 24/41 (58%) Query: 191 GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKK 231 G V+ +GGG G + +++ K + ++E+D+ +++ K Sbjct: 31 GNTVVEVGGGTGNLTKVLLQHPLKKLYVIELDREMVENLKS 71 >1J93-A nrPDB Length = 353 Score = 31.6 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 36/169 (21%), Positives = 65/169 (38%), Gaps = 16/169 (9%) Query: 130 RLVEYDIDEVV-YDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAIMGSGKED 188 + + + + Y DS Q ++I S + L V+ E L Y + I+ S K Sbjct: 189 QKFATSMAKYIRYQADSGAQAVQIFDS--WATEL---SPVDFEEFSLPYLKQIVDSVKLT 243 Query: 189 YTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMV--IDGCKKYMRKTC-GDVLDNLK 245 + +++ G GG+L +L V +V +D V DG ++ +D Sbjct: 244 HPNLPLILYASGSGGLLE---RLPLTGVDVVSLDWTVDMADGRRRLGPNVAIQGNVDPGV 300 Query: 246 GDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEF 294 + I + I + A +G+ I +L +PEE+ F Sbjct: 301 LFGSKEFITNRINDTVKKAGKGKH----ILNLGHGIKVGTPEENFAHFF 345 >6MRO-A nrPDB Length = 194 Score = 31.2 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 45/123 (36%), Gaps = 20/123 (16%) Query: 191 GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 L +G G G + K ++ ID K+ + ++ + Sbjct: 33 PGRALDIGCGRGENAIMLAKNG------CDVTG--IDLAKRAISDAKAKAIE--RHVKVN 82 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDG 310 ++ + + + + + EFD VI D + T E F R + KVLK+ G Sbjct: 83 FIVGNVLEMDQLF--TEDEFDIVI-DSGLFHVITDEERL---LFTRHVH----KVLKEGG 132 Query: 311 KYF 313 KYF Sbjct: 133 KYF 135 >2PJD-A nrPDB Length = 343 Score = 30.8 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 14/89 (15%), Positives = 33/89 (37%), Gaps = 7/89 (7%) Query: 152 ILHSKQFGNILILSGDVNLA-----ESD-LAYTRAIMGSGKEDYTGKDVLILGGGDGGIL 205 + +++F + G D L ++ S +T VL +G G G + Sbjct: 152 VFDAEKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLS 211 Query: 206 CEIVKLKPK-MVTMVEIDQMVIDGCKKYM 233 + PK +T+ ++ ++ + + Sbjct: 212 VAFARHSPKIRLTLCDVSAPAVEASRATL 240 >6CLW-A nrPDB Length = 364 Score = 30.8 bits (68), Expect = 0.91, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 17/22 (77%) Query: 192 KDVLILGGGDGGILCEIVKLKP 213 + V+ +GGG GG+L E+++ +P Sbjct: 191 RHVMDVGGGTGGVLAEVLRARP 212 >5BP7-A nrPDB Length = 271 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 35/114 (30%), Gaps = 14/114 (12%) Query: 154 HSKQFGNILILSGDVNLAESDLAYTRAI-------MGSGKEDYTGKDVLILGGGDGGILC 206 + F ++L + + ES I +G+ G VL LG G G +LC Sbjct: 16 ENLYFQSMLDIPRIFTITESAHRIHNPITPEKLTTLGAALRLEPGTRVLDLGSGSGEMLC 75 Query: 207 EIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIPVL 260 + I ID + + + + D + D + Sbjct: 76 TWARDHG-------IIGTGIDMSQLFTAQAKLRAEELGVADRVTFIHGDASGYV 122 >2PXX-A nrPDB Length = 215 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 56/154 (36%), Gaps = 25/154 (16%) Query: 173 SDLAYTRAIMGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVI---DGC 229 D + RA++ +L+LG G+ + E+ VT V+ +V+ C Sbjct: 27 GDFSSFRALLEPEL--RPEDRILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQAC 84 Query: 230 KKYMRKTCGDVLDNLKGD----CYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTS 285 ++ + + +D K D + V++E D ++ P + S Sbjct: 85 YAHVPQLRWETMDVRKLDFPSASFDVVLEKG------------TLDALLA-GERDPWTVS 131 Query: 286 PEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCV 319 E T + +L +VL G++ + + Sbjct: 132 SEGVHTVD---QVLSEVSRVLVPGGRFISMTSAA 162 >3ORF-A nrPDB Length = 251 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 52/162 (32%), Gaps = 35/162 (21%) Query: 184 SGKEDYTGKDVLILGGGDGGILCEIVK-LKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLD 242 + + K++L+L GG G + E+VK K K + ID + Sbjct: 15 VPRGSHMSKNILVL-GGSGALGAEVVKFFKSKSWNTISID-----------------FRE 56 Query: 243 NLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLS 302 N D + + +K ++ ++ S S+ EFL+ + + Sbjct: 57 NPNADHSFTIKDSGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKSVKGMI 116 Query: 303 --------------MKVLKQDGKYFTQGNCVNL--TEALSLY 328 K+L Q G + G L T + Y Sbjct: 117 DMNLYSAFASAHIGAKLLNQGGLFVLTGASAALNRTSGMIAY 158 >5XNC-A nrPDB Length = 371 Score = 29.3 bits (64), Expect = 2.9, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 44/120 (36%), Gaps = 21/120 (17%) Query: 191 GKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ 250 K+V +LG D + ++ PK + +++ID+ + +K D + + + Sbjct: 170 NKEVFVLGDDDLTSVALMLSGLPKRIAVLDIDERLTKFIEK--------AADEIGYENIE 221 Query: 251 VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDG 310 + D L YA FD I D T E +R + + LK G Sbjct: 222 IFTFDLRKPLPDYALHK--FDTFITDP-----------PETVEAIRAFVGRGIATLKGPG 268 >3QWB-A nrPDB Length = 334 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 39/128 (30%), Gaps = 29/128 (22%) Query: 199 GGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQVLIEDCIP 258 GG G IL +++K+K V + K+Y Sbjct: 159 GGVGLILNQLLKMKGAHTIAVASTDEKLKIAKEY-----------------------GAE 195 Query: 259 VLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNC 318 L +KE I + + S + ++S+ LK+ G + + GN Sbjct: 196 YLINASKED------ILRQVLKFTNGKGVDASFDSVGKDTFEISLAALKRKGVFVSFGNA 249 Query: 319 VNLTEALS 326 L S Sbjct: 250 SGLIPPFS 257 >5DXF-A nrPDB Length = 534 Score = 28.5 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 26/80 (32%), Gaps = 8/80 (10%) Query: 270 FDYVINDLTAVPISTSPEEDSTWEFLRLILDLSMKVLKQDGKYFTQGNCVNLTEALSLYE 329 F Y+ + T D F L+ V K G+ + + + L Sbjct: 160 FHYIQGQPSDGKAETDAWHDYVK-FNEAYLNKIKSVYKP-------GDIIWIHDYYLLLL 211 Query: 330 EQLGRLYCPVEFSKEIVCVP 349 QL R+ P + + VP Sbjct: 212 PQLLRMEFPNAYIGFFLHVP 231 >3L82-B nrPDB Length = 227 Score = 27.4 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 41/117 (35%), Gaps = 13/117 (11%) Query: 81 QGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVR-GGAIDRYWPTADGRLVEYDIDEV 139 + +EE S +NK+ R E R +P I + +D + A+ + Sbjct: 86 RAREEHTSAVNKMFSRHNEGDDQQGSRYSVIPQIQKVCEVVDGFIYVANAEAHKR----- 140 Query: 140 VYDEDSPYQNIKILHSKQFGN----ILILSGDVN--LAESDLAYTRAIMGSGKEDYT 190 ++ + +I + FG+ +L+LS + Y + ++ Sbjct: 141 -HEWQDEFSHIMAMTDPAFGSSGRPLLVLSCISQGDVKRMPCFYLAHELHLNLLNHP 196 >3L2O-B nrPDB Length = 312 Score = 27.4 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 41/117 (35%), Gaps = 13/117 (11%) Query: 81 QGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVR-GGAIDRYWPTADGRLVEYDIDEV 139 + +EE S +NK+ R E R +P I + +D + A+ + Sbjct: 171 RAREEHTSAVNKMFSRHNEGDDQQGSRYSVIPQIQKVCEVVDGFIYVANAEAHKR----- 225 Query: 140 VYDEDSPYQNIKILHSKQFGN----ILILSGDVN--LAESDLAYTRAIMGSGKEDYT 190 ++ + +I + FG+ +L+LS + Y + ++ Sbjct: 226 -HEWQDEFSHIMAMTDPAFGSSGRPLLVLSCISQGDVKRMPCFYLAHELHLNLLNHP 281 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.131 0.354 Lambda K H 0.267 0.0403 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,164,306 Number of Sequences: 36641 Number of extensions: 583479 Number of successful extensions: 2113 Number of sequences better than 10.0: 41 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 36 Number of HSP's that attempted gapping in prelim test: 1977 Number of HSP's gapped (non-prelim): 83 length of query: 366 length of database: 10,336,785 effective HSP length: 98 effective length of query: 268 effective length of database: 6,745,967 effective search space: 1807919156 effective search space used: 1807919156 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)