BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P51570 (392 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1WUU-A nrPDB 790 0.0 1S4E-A nrPDB 207 5e-54 2DEI-A nrPDB 201 4e-52 1PIE-A nrPDB 191 4e-49 2A2C-A nrPDB 150 8e-37 3V5R-A nrPDB 88 6e-18 2AJ4-A nrPDB 84 8e-17 1KKH-A nrPDB 61 1e-09 4HAC-B nrPDB 60 1e-09 2OI2-A nrPDB 54 2e-07 2R42-A nrPDB 44 1e-04 2HFU-A nrPDB 42 3e-04 2R3V-A nrPDB 37 0.020 5YYS-A nrPDB 32 0.41 4LUR-A nrPDB 30 2.6 >1WUU-A nrPDB Length = 399 Score = 790 bits (2040), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/391 (100%), Positives = 391/391 (100%) Query: 2 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMT 61 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMT Sbjct: 9 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMT 68 Query: 62 VLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP 121 VLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP Sbjct: 69 VLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP 128 Query: 122 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMP 181 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMP Sbjct: 129 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMP 188 Query: 182 CGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRR 241 CGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRR Sbjct: 189 CGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRR 248 Query: 242 QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYR 301 QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYR Sbjct: 249 QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYR 308 Query: 302 AFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA 361 AFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA Sbjct: 309 AFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA 368 Query: 362 PHAMRHIQEHYGGTATFYLSQAADGAKVLCL 392 PHAMRHIQEHYGGTATFYLSQAADGAKVLCL Sbjct: 369 PHAMRHIQEHYGGTATFYLSQAADGAKVLCL 399 >1S4E-A nrPDB Length = 352 Score = 207 bits (528), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 130/368 (35%), Positives = 198/368 (53%), Gaps = 25/368 (6%) Query: 29 ELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL 88 ++ V +PGRVNLIGEHTDY G V+PMA++L T++ + K V L SE +E + Sbjct: 3 KITVKSPGRVNLIGEHTDYTYGYVMPMAIDLYTII--TAEKYDKVQLY--SEHFNEEKTF 58 Query: 89 QFPLPTAQRSLEPGTPRWANYVKGVIQYY--PAAPLPGFSAVVVSSVPLGGGLSSSASLE 146 T + S W +YVKGV+ + G + +PLG GLSSSAS E Sbjct: 59 TLDNLTKEGS-------WIDYVKGVLWVLIQEGYKIGGLKGKITGDLPLGAGLSSSASFE 111 Query: 147 VATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSL 206 V L QL + +A + ++AE+ F G+PCGI+DQF + G+K + + +D ++L Sbjct: 112 VGILEVLNQLYNLNIDPLKKALLAKKAENEFVGVPCGILDQFAVVFGKKDNVIFLDTQTL 171 Query: 207 ETSLVPLSDPK-LAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEA 265 + +P PK ++VL+ + V+ LASSEY R+R EE R LGKES +EV ++L Sbjct: 172 QYEYIPF--PKDVSVLVFYTGVKRELASSEYAERKRIAEESLRILGKESSKEVTEKDLGK 229 Query: 266 ARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPEL 325 L K ++V E R + AL+ GD G+++ +H L ++Y VSC EL Sbjct: 230 LPPLHRK----FFSYIVRENARVLEVRDALKEGDIEKVGKILTTAHWDLAENYRVSCEEL 285 Query: 326 DQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPH----AMRHIQEHYGGTATFYLS 381 D V+ A+ + G YG+R+TG GFGG + L++ A +R + A +++ Sbjct: 286 DFFVKKAMEL-GAYGARLTGAGFGGSAIALVDKDKAKTIGDAILREYLAKFSWKAKYFVV 344 Query: 382 QAADGAKV 389 + +DG V Sbjct: 345 KPSDGVGV 352 >2DEI-A nrPDB Length = 350 Score = 201 bits (511), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 126/367 (34%), Positives = 193/367 (52%), Gaps = 25/367 (6%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQ 89 + V +PGRVNLIGEHTDY G V+PMA+ L T + K G V L + G + + Sbjct: 2 IKVKSPGRVNLIGEHTDYTYGYVMPMAINLYTKI--EAEKHGEVILYSEHFGEER----K 55 Query: 90 FPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP--LPGFSAVVVSSVPLGGGLSSSASLEV 147 F L ++ W +YVKG+ + + G V ++PLG GLSSSAS EV Sbjct: 56 FSLNDLRKE-----NSWIDYVKGIFWVLKESDYEVGGIKGRVSGNLPLGAGLSSSASFEV 110 Query: 148 ATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLE 207 L +L ++ + ++AE+ F G+PCGI+DQF + G++G+ + +D +L+ Sbjct: 111 GILETLDKLYNLKLDSLSKVLLAKKAENEFVGVPCGILDQFAVVFGREGNVIFLDTHTLD 170 Query: 208 TSLVPLSDPK-LAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAA 266 +P PK +++L+ + VR LASSEY R+ EE + LGK S +EV+ EL Sbjct: 171 YEYIPF--PKDVSILVFYTGVRRELASSEYAERKHIAEESLKILGKGSSKEVREGELSKL 228 Query: 267 RDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELD 326 L K ++V E R + AL+ G+ G+++ +H L +YEVSC ELD Sbjct: 229 PPLHRK----FFGYIVRENARVLEVRDALKEGNVEEVGKILTTAHWDLAKNYEVSCKELD 284 Query: 327 QLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA----PHAMRHIQEHYGGTATFYLSQ 382 VE AL + G YG+R+TG GFGG + L++ A +R + + A ++ + Sbjct: 285 FFVERALKL-GAYGARLTGAGFGGSAIALVDKEDAETIGEEILREYLKRFPWKARHFIVE 343 Query: 383 AADGAKV 389 +DG + Sbjct: 344 PSDGVGI 350 >1PIE-A nrPDB Length = 419 Score = 191 bits (486), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 140/392 (35%), Positives = 200/392 (51%), Gaps = 18/392 (4%) Query: 12 LLAEARRAFREEFGAEPELA-VSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKD 70 +L+ F E FG E+ +PGR+NLIGEHTDYN G V P ++ + T + R+D Sbjct: 30 VLSALTEKFAEVFGDTKEVEYFFSPGRINLIGEHTDYNGGYVFPASITIGTTGLARLRED 89 Query: 71 GLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPL---PGFSA 127 V L SE + ++F L ++ W+NYVKG+I A GF Sbjct: 90 KKVKLY--SENFPKLGVIEFDLDEVEK---KDGELWSNYVKGMIVMLKGAGYEIDKGFEL 144 Query: 128 VVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQ 187 ++ +P GLSSSASLE+ L L + Q+ Q+ E+ + G+ GI+DQ Sbjct: 145 LIKGEIPTASGLSSSASLELLVGVVLDDLFNLNVPRLELVQLGQKTENDYIGVNSGILDQ 204 Query: 188 FISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVA 247 F G+ A+ +DC +L+ +VP+ ++I N+N +L S+Y R + E Sbjct: 205 FAIGFGEVKKAIELDCNTLKYEMVPVELRDYDIVIMNTNKPRALTESKYNERFAETREAL 264 Query: 248 RA----LGKESLREVQLEELEAARDLVSKEGF-RRARHVVGEIRRTAQAAAALRRGDYRA 302 + L +SL E+ EE +A DL+ E +RARH V E RT A A G+ Sbjct: 265 KRMQTRLDIQSLGELSNEEFDANTDLIGDETLIKRARHAVYENNRTKIAQKAFVAGNLTK 324 Query: 303 FGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLL---EAS 359 FG L+ SH SL+DDYEV+ ELD L E A GV G+RMTG GFGGC + L+ S Sbjct: 325 FGELLNASHASLKDDYEVTGLELDTLAETAQKQAGVLGARMTGAGFGGCAIALVAHDNVS 384 Query: 360 AAPHAMRHIQEHYGGT-ATFYLSQAADGAKVL 390 A A+ + E G A+FY++Q G+ L Sbjct: 385 AFRKAVGQVYEEVVGYPASFYVAQIGSGSTKL 416 >2A2C-A nrPDB Length = 478 Score = 150 bits (380), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 127/429 (29%), Positives = 194/429 (45%), Gaps = 66/429 (15%) Query: 3 ALRQPQVAE--LLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM 60 A R+ QVAE L + + F +FG+ P+ V APGRVN+IGEH DY VLPMA+E Sbjct: 27 ATRRVQVAEHPRLLKLKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQD 86 Query: 61 TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANY----VKGVIQY 116 ++ P K + L T+ P F ++ P W NY +KG+ ++ Sbjct: 87 VLIAVEPVKTYALQLANTN-----PLYPDFSTSANNIQIDKTKPLWHNYFLCGLKGIQEH 141 Query: 117 YPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHS 176 + + L G + +V ++P GLSSS++L + + + A++C ++E Sbjct: 142 FGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSER- 200 Query: 177 FAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEY 236 + G G MDQ IS + ++G A LI+ L + V L + V+ + + A+S + Sbjct: 201 YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAATSHF 260 Query: 237 PVRRRQCEEVARALGKES---------LREVQ---------------------------- 259 +R +C A+ L K L EVQ Sbjct: 261 NIRVMECRLAAKLLAKYKSLQWDKVLRLEEVQAKLGISLEEMLLVTEDALHPEPYNPEEI 320 Query: 260 -------LEELEA------ARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGD---YRAF 303 LEEL +D++ + ++RA+HV E R Q + Sbjct: 321 CRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHVYSEAARVLQFKKICEEAPENMVQLL 380 Query: 304 GRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPH 363 G LM +SH S RD YE SCPELDQLV+ G GSR+TG G+GGCTV+++ A P Sbjct: 381 GELMNQSHMSCRDMYECSCPELDQLVDICRKF-GAQGSRLTGAGWGGCTVSMVPADKLPS 439 Query: 364 AMRHIQEHY 372 + ++ + Y Sbjct: 440 FLANVHKAY 448 >3V5R-A nrPDB Length = 505 Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 70/256 (27%), Positives = 118/256 (46%), Gaps = 26/256 (10%) Query: 19 AFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALEL-MTVLVGSPRKDGLVSLLT 77 AF + + +P+ +PGRVNLIGEH DY VLP+A+++ M V + LT Sbjct: 14 AFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLT 73 Query: 78 TSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVI------------QYYPAAPLPGF 125 ++ ++ PL + +++P W+NY K + + + PL G Sbjct: 74 NADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGA 133 Query: 126 SAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAAR--AQVCQQAEHSFAGMPCG 183 S +P GGGLSS+ + A T + + I+ + ++ AEH + G+ G Sbjct: 134 QIFCQSDIPTGGGLSSAFTCAAALATIRANMGKNFD-ISKKDLTRITAVAEH-YVGVNNG 191 Query: 184 IMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKL-----AVLITNSNVRHS---LASSE 235 MDQ S+ G++ HAL ++ R + P P+L + +I N+ V+ + A + Sbjct: 192 GMDQATSVYGEEDHALYVEFRP-KLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTN 250 Query: 236 YPVRRRQCEEVARALG 251 Y +R + A AL Sbjct: 251 YNLRVIEVTVAANALA 266 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 37/93 (39%), Positives = 51/93 (54%), Gaps = 8/93 (8%) Query: 275 FRRARHVVGEIRRTAQAAAALRRGDYRA-------FGRLMVESHRSLRDDYEVSCPELDQ 327 ++RA+HV E R +A + + FGRLM ES S YE SC E +Q Sbjct: 368 YQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQ 427 Query: 328 LVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA 360 + ALA G +GSR+TG G+GGCT+ L+ + A Sbjct: 428 ICSIALA-NGSFGSRLTGAGWGGCTIHLVPSGA 459 >2AJ4-A nrPDB Length = 548 Score = 84.3 bits (207), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 70/266 (26%), Positives = 116/266 (43%), Gaps = 26/266 (9%) Query: 9 VAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALEL-MTVLVGSP 67 +AE + F + A+P+ +PGRVNLIGEH DY VLP+A++ M V Sbjct: 45 LAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVL 104 Query: 68 RKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQY----------- 116 + L ++ ++ PL + +++P W+NY K + Sbjct: 105 NEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPE 164 Query: 117 -YPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAAR---AQVCQQ 172 + +APL G VP G GLSSSA+ A + + G ++ ++ Sbjct: 165 RFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVV 224 Query: 173 AEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKL-----AVLITNSNV 227 AEH + G+ G MDQ S+ G++ HAL ++ + + P P+L + +I N+ V Sbjct: 225 AEH-YVGVNNGGMDQAASVCGEEDHALYVEFKP-QLKATPFKFPQLKNHEISFVIANTLV 282 Query: 228 ---RHSLASSEYPVRRRQCEEVARAL 250 + A + Y +R + A L Sbjct: 283 VSNKFETAPTNYNLRVVEVTTAANVL 308 Score = 71.2 bits (173), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 38/89 (42%), Positives = 51/89 (57%), Gaps = 8/89 (8%) Query: 275 FRRARHVVGEIRRTAQAAAALRRGDYRA-------FGRLMVESHRSLRDDYEVSCPELDQ 327 ++RA+HV E R +A + + A FG LM ES S YE SCPE+D+ Sbjct: 411 YQRAKHVYSESLRVLKAVKLMTTASFTADEDFFKQFGALMNESQASCDKLYECSCPEIDK 470 Query: 328 LVEAALAVPGVYGSRMTGGGFGGCTVTLL 356 + AL+ G YGSR+TG G+GGCTV L+ Sbjct: 471 ICSIALS-NGSYGSRLTGAGWGGCTVHLV 498 >1KKH-A nrPDB Length = 317 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 77/338 (22%), Positives = 136/338 (40%), Gaps = 63/338 (18%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELM-TVLVGSPRKDGLVSLLTTSEGADEPQRL 88 + + P +V L GEH + MA++L T+ + ++D ++ L D + L Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLN-----DLNKSL 60 Query: 89 QFPLPTAQRSLEPGTPRWANY----VKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSAS 144 L +++ P Y +K + Y P GF + S +P+ GL SSAS Sbjct: 61 GLNLNEI-KNINPNNFGDFKYCLCAIKNTLDYLNIEPKTGFKINISSKIPISCGLGSSAS 119 Query: 145 LEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQ------KGHA 198 + + GTI A + + + D I+ +G +G A Sbjct: 120 ITI-------------GTIKAVSGFYNKE----------LKDDEIAKLGYMVEKEIQGKA 156 Query: 199 LLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREV 258 + D TS + K + I N+ R E+ + C+ + K + Sbjct: 157 SITD-----TSTITY---KGILEIKNNKFRK--IKGEFEEFLKNCKFLIVYAEKRKKKTA 206 Query: 259 QLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDY 318 +L E A+ E F+ V+ E AL+ + FG+LM ++H L+ Sbjct: 207 ELVN-EVAKIENKDEIFKEIDKVIDE---------ALKIKNKEDFGKLMTKNHELLKK-L 255 Query: 319 EVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLL 356 +S P+LD++V+ +G+++TG G GGC + L+ Sbjct: 256 NISTPKLDRIVDIGNRFG--FGAKLTGAGGGGCVIILV 291 >4HAC-B nrPDB Length = 321 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 72/267 (26%), Positives = 114/267 (42%), Gaps = 45/267 (16%) Query: 109 YVKGVIQYY-PAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARA 167 YV VI+ + P+ G V S +P+G GL SSA++ +A+ L +L ++ A Sbjct: 81 YVSAVIEKMRKSIPINGVFLTVDSDIPVGSGLGSSAAVTIASIGALNELFGFGLSLQEIA 140 Query: 168 QVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNV 227 ++ + E G D ++S G G + + R L+T P ++I ++ V Sbjct: 141 KLGHEIEIKVQG-AASPTDTYVSTFG--GVVTIPERRKLKT-------PDCGIVIGDTGV 190 Query: 228 RHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRR 287 S + E RQ E L +E L + +G+I R Sbjct: 191 FSS--TKELVANVRQLRESYPDL---------IEPLMTS---------------IGKISR 224 Query: 288 TAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGG 347 + + GDY + GRLM ++ L D V+ EL QL+ +A A G +G+++TG G Sbjct: 225 IGEQL--VLSGDYASIGRLM-NVNQGLLDALGVNILELSQLIYSARAA-GAFGAKITGAG 280 Query: 348 FGGCTVTLLEASAAPHAMRHIQEHYGG 374 GGC V L AP + E G Sbjct: 281 GGGCMVAL----TAPEKCNQVAEAVAG 303 >2OI2-A nrPDB Length = 292 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 30/77 (38%), Positives = 47/77 (61%), Gaps = 4/77 (5%) Query: 280 HVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVY 339 H +GE+ T QA A+ + D G+++ ++H L++ VS E D LVE AL+ G Sbjct: 194 HALGEL--TQQAEIAISQKDAEGLGQILSQAHLHLKE-IGVSSLEADSLVETALS-HGAL 249 Query: 340 GSRMTGGGFGGCTVTLL 356 G++M+GGG GGC + L+ Sbjct: 250 GAKMSGGGLGGCIIALV 266 >2R42-A nrPDB Length = 395 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 72/261 (27%), Positives = 100/261 (38%), Gaps = 62/261 (23%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 88 L VSAPG+V L GEH + + L +AL L T LV P+ +G VSL + G + + Sbjct: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 Query: 89 -------------QFPLPTAQRSLEP-----GTPRWANYVKGVIQYYPAA---------- 120 P PT ++ LE G PR +G+ Sbjct: 66 TLQLLDTGFLEQGDVPAPTLEQ-LEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQR 124 Query: 121 PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-------PDSGTIAAR------- 166 LP +V S +P G GL SSA+ V L C D G+I + Sbjct: 125 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 184 Query: 167 -AQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHALLIDCRSLETSLVPLSDPKLAV 220 + + E G P G+ D +S G Q+G +SL L P L + Sbjct: 185 INKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQGKM---------SSLKRL--PALQI 232 Query: 221 LITNSNVRHSLASSEYPVRRR 241 L+TN+ V S + VR R Sbjct: 233 LLTNTKVPRSTKALVAGVRSR 253 >2HFU-A nrPDB Length = 332 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 41/72 (56%), Gaps = 2/72 (2%) Query: 288 TAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGG 347 +QA AL++GD + G+LM +H R +VSC EL+ +V+ G G++++G G Sbjct: 230 VSQAREALQKGDLQRLGQLMNANHDLCR-QIDVSCRELESIVQTCRTY-GALGAKLSGTG 287 Query: 348 FGGCTVTLLEAS 359 GG V L +S Sbjct: 288 RGGIAVALAASS 299 >2R3V-A nrPDB Length = 396 Score = 36.6 bits (83), Expect = 0.020, Method: Compositional matrix adjust. Identities = 70/257 (27%), Positives = 97/257 (37%), Gaps = 54/257 (21%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEG---ADEPQ 86 L VSAPG+V L GEH + + L ++L L T L P +G V L + G A + Sbjct: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 Query: 87 RLQ-----------FPLPTAQRSLE----PGTP-------RWANYVKGVIQYYPAA---- 120 RLQ PT+++ + G P R A V + Y + Sbjct: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLA--VLAFLYLYLSICRKQ 123 Query: 121 -PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPD------SGTIAAR------- 166 LP VV S +P G GL SSA+ V L +C + G R Sbjct: 124 RALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLE 183 Query: 167 --AQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITN 224 + Q E G P G+ D +S G SL+ S P L +L+TN Sbjct: 184 LINKWAFQGERMIHGNPSGV-DNAVSTWGGALRYHQGKISSLKRS------PALQILLTN 236 Query: 225 SNVRHSLASSEYPVRRR 241 + V + + VR R Sbjct: 237 TKVPRNTRALVAGVRNR 253 >5YYS-A nrPDB Length = 949 Score = 32.3 bits (72), Expect = 0.41, Method: Compositional matrix adjust. Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 27/163 (16%) Query: 34 APGRVNLIGEHTD------YNQGLVLPMALEL-----MTVLVGSPRKDGLVSLLTTSEGA 82 +P R+++ G TD Y+ G V+ +A+EL + V V P KD + L + GA Sbjct: 589 SPVRIDMAGGWTDTPPYSLYSGGNVVNLAIELNGQPPLQVYV-KPCKDFHIVLRSIDMGA 647 Query: 83 -------DEPQRLQ-----FPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVV 130 DE Q + F +P A SL P ++ ++ G ++ Sbjct: 648 MEIVSTFDELQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLL 707 Query: 131 SSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQA 173 +++P G GL +S+ L + C G + ++CQ+ Sbjct: 708 AAIPAGSGLGTSSILASTVLGAINDFC---GLAWDKNEICQRT 747 >4LUR-A nrPDB Length = 309 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 10/115 (8%) Query: 177 FAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEY 236 A M MD + S G ID S T ++ +SDP + + V+ +++ S Sbjct: 6 IADMAKIFMDNYCSPEKLTGMEEAIDAASSNTEILSISDPTMLANVLTDGVKKTISDSRV 65 Query: 237 PVRRRQCEEVARALGKESLREVQLEELEA-ARDLVSKE------GFRRARHVVGE 284 V +A ++ ++ LE L A + V E G+ + +H++GE Sbjct: 66 KVTYEPDLILA---APPAMPDIPLEHLAAMIKGTVKVEILEGNIGYLKIQHIIGE 117 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1WUU-A nrPDB 522 e-148 2A2C-A nrPDB 386 e-107 2DEI-A nrPDB 383 e-107 1S4E-A nrPDB 376 e-104 1PIE-A nrPDB 373 e-103 2AJ4-A nrPDB 264 4e-71 3V5R-A nrPDB 251 4e-67 1KKH-A nrPDB 235 2e-62 4HAC-B nrPDB 208 3e-54 2R42-A nrPDB 161 4e-40 2HFU-A nrPDB 145 4e-35 2OI2-A nrPDB 101 7e-22 Sequences not found previously or not previously below threshold: 2R3V-A nrPDB 133 1e-31 4N3O-A nrPDB 84 1e-16 2X7I-A nrPDB 82 4e-16 4UT4-A nrPDB 77 2e-14 3K85-A nrPDB 68 5e-12 5YYS-A nrPDB 53 3e-07 3HUL-A nrPDB 51 8e-07 4P52-A nrPDB 50 2e-06 3K17-A nrPDB 49 3e-06 4RPF-A nrPDB 42 4e-04 2V2V-A nrPDB 41 0.001 2HKE-A nrPDB 38 0.005 3PYF-A nrPDB 35 0.054 4EMD-A nrPDB 34 0.15 5WAT-A nrPDB 33 0.20 1UEK-A nrPDB 32 0.39 2OG2-A nrPDB 32 0.48 5L3R-B nrPDB 32 0.49 2WW4-A nrPDB 32 0.53 3J6B-S nrPDB 29 3.6 1H73-A nrPDB 29 3.8 5WAS-A nrPDB 29 4.9 3KAK-A nrPDB 28 6.2 1KWK-A nrPDB 28 8.5 >1WUU-A nrPDB Length = 399 Score = 522 bits (1343), Expect = e-148, Method: Composition-based stats. Identities = 391/391 (100%), Positives = 391/391 (100%) Query: 2 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMT 61 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMT Sbjct: 9 AALRQPQVAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMT 68 Query: 62 VLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP 121 VLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP Sbjct: 69 VLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP 128 Query: 122 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMP 181 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMP Sbjct: 129 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMP 188 Query: 182 CGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRR 241 CGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRR Sbjct: 189 CGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRR 248 Query: 242 QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYR 301 QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYR Sbjct: 249 QCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYR 308 Query: 302 AFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA 361 AFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA Sbjct: 309 AFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA 368 Query: 362 PHAMRHIQEHYGGTATFYLSQAADGAKVLCL 392 PHAMRHIQEHYGGTATFYLSQAADGAKVLCL Sbjct: 369 PHAMRHIQEHYGGTATFYLSQAADGAKVLCL 399 >2A2C-A nrPDB Length = 478 Score = 386 bits (990), Expect = e-107, Method: Composition-based stats. Identities = 131/456 (28%), Positives = 201/456 (44%), Gaps = 75/456 (16%) Query: 3 ALRQPQVAE--LLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELM 60 A R+ QVAE L + + F +FG+ P+ V APGRVN+IGEH DY VLPMA+E Sbjct: 27 ATRRVQVAEHPRLLKLKEMFNSKFGSIPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQD 86 Query: 61 TVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYV----KGVIQY 116 ++ P K + L T+ P F ++ P W NY KG+ ++ Sbjct: 87 VLIAVEPVKTYALQLANTN-----PLYPDFSTSANNIQIDKTKPLWHNYFLCGLKGIQEH 141 Query: 117 YPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHS 176 + + L G + +V ++P GLSSS++L + + + A++C ++E Sbjct: 142 FGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVELAEICAKSER- 200 Query: 177 FAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEY 236 + G G MDQ IS + ++G A LI+ L + V L + V+ + + A+S + Sbjct: 201 YIGTEGGGMDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAATSHF 260 Query: 237 PVRRRQCEEVARALGKES---------LREVQ---------------------------- 259 +R +C A+ L K L EVQ Sbjct: 261 NIRVMECRLAAKLLAKYKSLQWDKVLRLEEVQAKLGISLEEMLLVTEDALHPEPYNPEEI 320 Query: 260 -------LEELEA------ARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGD---YRAF 303 LEEL +D++ + ++RA+HV E R Q + Sbjct: 321 CRCLGISLEELRTQILSPNTQDVLIFKLYQRAKHVYSEAARVLQFKKICEEAPENMVQLL 380 Query: 304 GRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPH 363 G LM +SH S RD YE SCPELDQLV+ G GSR+TG G+GGCTV+++ A P Sbjct: 381 GELMNQSHMSCRDMYECSCPELDQLVDICRKF-GAQGSRLTGAGWGGCTVSMVPADKLPS 439 Query: 364 AMRHIQEHY---------GGTATFYLSQAADGAKVL 390 + ++ + Y + + ++ GA VL Sbjct: 440 FLANVHKAYYQRSDGSLAPEKQSLFATKPGGGALVL 475 >2DEI-A nrPDB Length = 350 Score = 383 bits (984), Expect = e-107, Method: Composition-based stats. Identities = 123/366 (33%), Positives = 190/366 (51%), Gaps = 23/366 (6%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQ 89 + V +PGRVNLIGEHTDY G V+PMA+ L T + K G V L + G + + Sbjct: 2 IKVKSPGRVNLIGEHTDYTYGYVMPMAINLYTKI--EAEKHGEVILYSEHFGEER----K 55 Query: 90 FPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPL--PGFSAVVVSSVPLGGGLSSSASLEV 147 F L ++ W +YVKG+ + G V ++PLG GLSSSAS EV Sbjct: 56 FSLNDLRKE-----NSWIDYVKGIFWVLKESDYEVGGIKGRVSGNLPLGAGLSSSASFEV 110 Query: 148 ATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLE 207 L +L ++ + ++AE+ F G+PCGI+DQF + G++G+ + +D +L+ Sbjct: 111 GILETLDKLYNLKLDSLSKVLLAKKAENEFVGVPCGILDQFAVVFGREGNVIFLDTHTLD 170 Query: 208 TSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAAR 267 +P +++L+ + VR LASSEY R+ EE + LGK S +EV+ EL Sbjct: 171 YEYIPFPK-DVSILVFYTGVRRELASSEYAERKHIAEESLKILGKGSSKEVREGELSKLP 229 Query: 268 DLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQ 327 L + ++V E R + AL+ G+ G+++ +H L +YEVSC ELD Sbjct: 230 PLHR----KFFGYIVRENARVLEVRDALKEGNVEEVGKILTTAHWDLAKNYEVSCKELDF 285 Query: 328 LVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAA----PHAMRHIQEHYGGTATFYLSQA 383 VE AL + G YG+R+TG GFGG + L++ A +R + + A ++ + Sbjct: 286 FVERALKL-GAYGARLTGAGFGGSAIALVDKEDAETIGEEILREYLKRFPWKARHFIVEP 344 Query: 384 ADGAKV 389 +DG + Sbjct: 345 SDGVGI 350 >1S4E-A nrPDB Length = 352 Score = 376 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 127/367 (34%), Positives = 196/367 (53%), Gaps = 23/367 (6%) Query: 29 ELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL 88 ++ V +PGRVNLIGEHTDY G V+PMA++L T++ + K V L SE +E + Sbjct: 3 KITVKSPGRVNLIGEHTDYTYGYVMPMAIDLYTII--TAEKYDKVQLY--SEHFNEEKTF 58 Query: 89 QFPLPTAQRSLEPGTPRWANYVKGVIQYY--PAAPLPGFSAVVVSSVPLGGGLSSSASLE 146 T + S W +YVKGV+ + G + +PLG GLSSSAS E Sbjct: 59 TLDNLTKEGS-------WIDYVKGVLWVLIQEGYKIGGLKGKITGDLPLGAGLSSSASFE 111 Query: 147 VATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSL 206 V L QL + +A + ++AE+ F G+PCGI+DQF + G+K + + +D ++L Sbjct: 112 VGILEVLNQLYNLNIDPLKKALLAKKAENEFVGVPCGILDQFAVVFGKKDNVIFLDTQTL 171 Query: 207 ETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAA 266 + +P ++VL+ + V+ LASSEY R+R EE R LGKES +EV ++L Sbjct: 172 QYEYIPFPK-DVSVLVFYTGVKRELASSEYAERKRIAEESLRILGKESSKEVTEKDLGKL 230 Query: 267 RDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELD 326 L + ++V E R + AL+ GD G+++ +H L ++Y VSC ELD Sbjct: 231 PPLHR----KFFSYIVRENARVLEVRDALKEGDIEKVGKILTTAHWDLAENYRVSCEELD 286 Query: 327 QLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPH----AMRHIQEHYGGTATFYLSQ 382 V+ A+ + G YG+R+TG GFGG + L++ A +R + A +++ + Sbjct: 287 FFVKKAMEL-GAYGARLTGAGFGGSAIALVDKDKAKTIGDAILREYLAKFSWKAKYFVVK 345 Query: 383 AADGAKV 389 +DG V Sbjct: 346 PSDGVGV 352 >1PIE-A nrPDB Length = 419 Score = 373 bits (956), Expect = e-103, Method: Composition-based stats. Identities = 140/397 (35%), Positives = 202/397 (50%), Gaps = 18/397 (4%) Query: 7 PQVAELLAEARRAFREEFGAEPEL-AVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVG 65 + + +L+ F E FG E+ +PGR+NLIGEHTDYN G V P ++ + T + Sbjct: 25 VENSTVLSALTEKFAEVFGDTKEVEYFFSPGRINLIGEHTDYNGGYVFPASITIGTTGLA 84 Query: 66 SPRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPL--- 122 R+D V L SE + ++F L ++ W+NYVKG+I A Sbjct: 85 RLREDKKVKLY--SENFPKLGVIEFDLDEVEK---KDGELWSNYVKGMIVMLKGAGYEID 139 Query: 123 PGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPC 182 GF ++ +P GLSSSASLE+ L L + Q+ Q+ E+ + G+ Sbjct: 140 KGFELLIKGEIPTASGLSSSASLELLVGVVLDDLFNLNVPRLELVQLGQKTENDYIGVNS 199 Query: 183 GIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQ 242 GI+DQF G+ A+ +DC +L+ +VP+ ++I N+N +L S+Y R + Sbjct: 200 GILDQFAIGFGEVKKAIELDCNTLKYEMVPVELRDYDIVIMNTNKPRALTESKYNERFAE 259 Query: 243 CEEVAR----ALGKESLREVQLEELEAARDLVSKEGF-RRARHVVGEIRRTAQAAAALRR 297 E + L +SL E+ EE +A DL+ E +RARH V E RT A A Sbjct: 260 TREALKRMQTRLDIQSLGELSNEEFDANTDLIGDETLIKRARHAVYENNRTKIAQKAFVA 319 Query: 298 GDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLL- 356 G+ FG L+ SH SL+DDYEV+ ELD L E A GV G+RMTG GFGGC + L+ Sbjct: 320 GNLTKFGELLNASHASLKDDYEVTGLELDTLAETAQKQAGVLGARMTGAGFGGCAIALVA 379 Query: 357 --EASAAPHAMRHIQEHYGGT-ATFYLSQAADGAKVL 390 SA A+ + E G A+FY++Q G+ L Sbjct: 380 HDNVSAFRKAVGQVYEEVVGYPASFYVAQIGSGSTKL 416 >2AJ4-A nrPDB Length = 548 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 70/267 (26%), Positives = 117/267 (43%), Gaps = 26/267 (9%) Query: 9 VAELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALEL-MTVLVGSP 67 +AE + F + A+P+ +PGRVNLIGEH DY VLP+A++ M V Sbjct: 45 LAEKCPSIIKKFISAYDAKPDFVARSPGRVNLIGEHIDYCDFSVLPLAIDFDMLCAVKVL 104 Query: 68 RKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVI------------Q 115 + L ++ ++ PL + +++P W+NY K + + Sbjct: 105 NEKNPSITLINADPKFAQRKFDLPLDGSYVTIDPSVSDWSNYFKCGLHVAHSFLKKLAPE 164 Query: 116 YYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAAR---AQVCQQ 172 + +APL G VP G GLSSSA+ A + + G ++ ++ Sbjct: 165 RFASAPLAGLQVFCEGDVPTGSGLSSSAAFICAVALAVVKANMGPGYHMSKQNLMRITVV 224 Query: 173 AEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKL-----AVLITNSNV 227 AEH + G+ G MDQ S+ G++ HAL ++ + + P P+L + +I N+ V Sbjct: 225 AEH-YVGVNNGGMDQAASVCGEEDHALYVEFKP-QLKATPFKFPQLKNHEISFVIANTLV 282 Query: 228 ---RHSLASSEYPVRRRQCEEVARALG 251 + A + Y +R + A L Sbjct: 283 VSNKFETAPTNYNLRVVEVTTAANVLA 309 Score = 115 bits (287), Expect = 4e-26, Method: Composition-based stats. Identities = 41/114 (35%), Positives = 57/114 (50%), Gaps = 9/114 (7%) Query: 254 SLREVQLEELEAARD-LVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRA-------FGR 305 S E + L + + ++RA+HV E R +A + + A FG Sbjct: 389 SREEFTRDYLTTSPVRFQVLKLYQRAKHVYSESLRVLKAVKLMTTASFTADEDFFKQFGA 448 Query: 306 LMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEAS 359 LM ES S YE SCPE+D++ AL+ G YGSR+TG G+GGCTV L+ Sbjct: 449 LMNESQASCDKLYECSCPEIDKICSIALS-NGSYGSRLTGAGWGGCTVHLVPGG 501 >3V5R-A nrPDB Length = 505 Score = 251 bits (641), Expect = 4e-67, Method: Composition-based stats. Identities = 72/297 (24%), Positives = 124/297 (41%), Gaps = 24/297 (8%) Query: 11 ELLAEARRAFREEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALEL-MTVLVGSPRK 69 + AF + + +P+ +PGRVNLIGEH DY VLP+A+++ M V + Sbjct: 6 QKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDE 65 Query: 70 DGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVI------------QYY 117 LT ++ ++ PL + +++P W+NY K + + + Sbjct: 66 KNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERF 125 Query: 118 PAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-PDSGTIAARAQVCQQAEHS 176 PL G S +P GGGLSS+ + A T + + ++ AEH Sbjct: 126 NNTPLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEH- 184 Query: 177 FAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKL-----AVLITNSNVRH-- 229 + G+ G MDQ S+ G++ HAL ++ R + P P+L + +I N+ V+ Sbjct: 185 YVGVNNGGMDQATSVYGEEDHALYVEFRP-KLKATPFKFPQLKNHEISFVIANTLVKSNK 243 Query: 230 -SLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEI 285 A + Y +R + A AL + + + + + F A + E Sbjct: 244 FETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYEN 300 Score = 117 bits (293), Expect = 7e-27, Method: Composition-based stats. Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 8/95 (8%) Query: 273 EGFRRARHVVGEIRRTAQAAAALRRGDYR-------AFGRLMVESHRSLRDDYEVSCPEL 325 + ++RA+HV E R +A + + FGRLM ES S YE SC E Sbjct: 366 KLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIET 425 Query: 326 DQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASA 360 +Q+ ALA G +GSR+TG G+GGCT+ L+ + A Sbjct: 426 NQICSIALA-NGSFGSRLTGAGWGGCTIHLVPSGA 459 >1KKH-A nrPDB Length = 317 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 71/332 (21%), Positives = 129/332 (38%), Gaps = 51/332 (15%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELM-TVLVGSPRKDGLVSLLTTSEGADEPQRL 88 + + P +V L GEH + MA++L T+ + ++D ++ L D + L Sbjct: 6 MIIETPSKVILFGEHAVVYGYRAISMAIDLTSTIEIKETQEDEIILNLN-----DLNKSL 60 Query: 89 QFPLPTAQRSLEPGTPRWANY----VKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSAS 144 L +++ P Y +K + Y P GF + S +P+ GL SSAS Sbjct: 61 GLNLNEI-KNINPNNFGDFKYCLCAIKNTLDYLNIEPKTGFKINISSKIPISCGLGSSAS 119 Query: 145 LEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCR 204 + + T + A++ E +G A + D Sbjct: 120 ITIGTIKAVSGFYNKELKDDEIAKLGYMVEKEI-----------------QGKASITDTS 162 Query: 205 SLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELE 264 ++ K + I N+ R E+ + C+ + K + +L E Sbjct: 163 TITY--------KGILEIKNNKFRK--IKGEFEEFLKNCKFLIVYAEKRKKKTAELVN-E 211 Query: 265 AARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPE 324 A+ E F+ V+ E AL+ + FG+LM ++H L+ +S P+ Sbjct: 212 VAKIENKDEIFKEIDKVIDE---------ALKIKNKEDFGKLMTKNHELLKK-LNISTPK 261 Query: 325 LDQLVEAALAVPGVYGSRMTGGGFGGCTVTLL 356 LD++V+ +G+++TG G GGC + L+ Sbjct: 262 LDRIVDIGNRFG--FGAKLTGAGGGGCVIILV 291 >4HAC-B nrPDB Length = 321 Score = 208 bits (530), Expect = 3e-54, Method: Composition-based stats. Identities = 86/343 (25%), Positives = 134/343 (39%), Gaps = 65/343 (18%) Query: 33 SAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPL 92 SAPG++ L GEH + A+EL T + + G D + Sbjct: 25 SAPGKIYLFGEHAVVYGETAIACAVELRTRVRAELNDSITIQSQIGRTGLDFEKHP---- 80 Query: 93 PTAQRSLEPGTPRWANYVKGVIQYY-PAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYT 151 YV VI+ + P+ G V S +P+G GL SSA++ +A+ Sbjct: 81 ----------------YVSAVIEKMRKSIPINGVFLTVDSDIPVGSGLGSSAAVTIASIG 124 Query: 152 FLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLV 211 L +L ++ A++ + E G D ++S G G + + R L+T Sbjct: 125 ALNELFGFGLSLQEIAKLGHEIEIKVQG-AASPTDTYVSTFG--GVVTIPERRKLKT--- 178 Query: 212 PLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVS 271 P ++I ++ V S E RQ E L +E L + Sbjct: 179 ----PDCGIVIGDTGVFSST--KELVANVRQLRESYPDL---------IEPLMTS----- 218 Query: 272 KEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEA 331 +G+I R + + GDY + GRLM ++ L D V+ EL QL+ + Sbjct: 219 ----------IGKISRIGEQL--VLSGDYASIGRLMN-VNQGLLDALGVNILELSQLIYS 265 Query: 332 ALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGG 374 A A G +G+++TG G GGC V L AP + E G Sbjct: 266 ARA-AGAFGAKITGAGGGGCMVAL----TAPEKCNQVAEAVAG 303 >2R42-A nrPDB Length = 395 Score = 161 bits (408), Expect = 4e-40, Method: Composition-based stats. Identities = 95/394 (24%), Positives = 137/394 (34%), Gaps = 86/394 (21%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 88 L VSAPG+V L GEH + + L +AL L T LV P+ +G VSL + G + + Sbjct: 6 LLVSAPGKVILHGEHAVVHGKVALAVALNLRTFLVLRPQSNGKVSLNLPNVGIKQVWDVA 65 Query: 89 -------------QFPLPTAQRSLEP-----GTPRWANYVKGVIQYY----------PAA 120 P PT ++ LE G PR +G+ Sbjct: 66 TLQLLDTGFLEQGDVPAPTLEQ-LEKLKKVAGLPRDCVGNEGLSLLAFLYLYLAICRKQR 124 Query: 121 PLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLC-------PDSGTIAAR------- 166 LP +V S +P G GL SSA+ V L C D G+I + Sbjct: 125 TLPSLDIMVWSELPPGAGLGSSAAYSVCVAAALLTACEEVTNPLKDRGSIGSWPEEDLKS 184 Query: 167 -AQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHALLIDCRSLETSLVPLSDPKLAV 220 + + E G P G+ D +S G Q+G + P L + Sbjct: 185 INKWAYEGERVIHGNPSGV-DNSVSTWGGALRYQQGKMSSLKR-----------LPALQI 232 Query: 221 LITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARH 280 L+TN+ V S + VR R + E+ A Sbjct: 233 LLTNTKVPRSTKALVAGVRSRLIKFP---------------EIMAPLLTSIDAISLECER 277 Query: 281 VVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYG 340 V+GE+ L LM + L + V LDQL + A Sbjct: 278 VLGEMAAAPVPEQYLV------LEELMDMNQHHL-NALGVGHASLDQLCQVTAAHG--LH 328 Query: 341 SRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGG 374 S++TG G GGC +TLL+ + ++ G Sbjct: 329 SKLTGAGGGGCGITLLKPGLERAKVEAAKQALTG 362 >2HFU-A nrPDB Length = 332 Score = 145 bits (364), Expect = 4e-35, Method: Composition-based stats. Identities = 66/359 (18%), Positives = 123/359 (34%), Gaps = 51/359 (14%) Query: 36 GRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPLPTA 95 G+V L GEH + + + T + + + P Sbjct: 20 GKVILFGEHFVVHGAEAIVAGISEYTECRLE---------INPGVPGLQ---VDDQRPAI 67 Query: 96 QRSLEPGTPRWANYVKGVIQYYPAAPLP-GFSAVVVSSVPLGGGLSSSASLEVATYTFLQ 154 + + V+ + G + + G+ +SAS VA L Sbjct: 68 PGYIAQKRDEQIKAHQLVLDHLKVDLSGDGLKMFIGGPLVPSSGIGASASDVVAFSRALS 127 Query: 155 QLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLS 214 +L + T E + G P G D + G +L ++ ++ P++ Sbjct: 128 ELYQLNLTDEEVNLSAFVGEGGYHGTPSGA-DNTAATYG---GLILYRRQNGKSVFKPIA 183 Query: 215 DPK-LAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKE 273 + L +++ + + S A V + K + + + K Sbjct: 184 FQQRLYLVVVGTGINASTAK------------VVNDVHKMKQQ----------QPVQFKR 221 Query: 274 GFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAAL 333 + H+V QA AL++GD + G+LM +H R +VSC EL+ +V+ Sbjct: 222 LYDNYTHIVS------QAREALQKGDLQRLGQLMNANHDLCR-QIDVSCRELESIVQTCR 274 Query: 334 AVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGTATF---YLSQAADGAKV 389 G G++++G G GG V L +S A+ + A F Y Q + + + Sbjct: 275 TY-GALGAKLSGTGRGGIAVALAASSDQRDAIVKGLKAKCPEAKFIWRYTVQPSAASNL 332 >2R3V-A nrPDB Length = 396 Score = 133 bits (335), Expect = 1e-31, Method: Composition-based stats. Identities = 77/358 (21%), Positives = 117/358 (32%), Gaps = 74/358 (20%) Query: 30 LAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL- 88 L VSAPG+V L GEH + + L ++L L T L P +G V L + G + Sbjct: 6 LLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVA 65 Query: 89 -------------QFPLPTAQRSLE----PGTPRWANYVKGVIQYYPAA----------P 121 PT+++ + G P + + Sbjct: 66 RLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRA 125 Query: 122 LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAA---------------R 166 LP VV S +P G GL SSA+ V L +C + Sbjct: 126 LPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELI 185 Query: 167 AQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSN 226 + Q E G P G+ D +S G + + S + P L +L+TN+ Sbjct: 186 NKWAFQGERMIHGNPSGV-DNAVSTWGGA-----LRYHQGKISSLK-RSPALQILLTNTK 238 Query: 227 VRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIR 286 V + + VR R + L + D +S E R V+GE+ Sbjct: 239 VPRNTRALVAGVRNRLLKFPEIVA-----------PLLTSIDAISLECER----VLGEMG 283 Query: 287 RTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMT 344 L + M + H + V LDQL + A S++T Sbjct: 284 EAPAPEQYLVLEELID----MNQHHL---NALGVGHASLDQLCQVTRARG--LHSKLT 332 >2OI2-A nrPDB Length = 292 Score = 101 bits (250), Expect = 7e-22, Method: Composition-based stats. Identities = 70/345 (20%), Positives = 121/345 (35%), Gaps = 78/345 (22%) Query: 33 SAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPL 92 A ++ LIGEH + + L V + A+ P RL + Sbjct: 9 QAHSKIILIGEHAVVYGYPAISLPL-------------LEVEVTCKVVPAESPWRL-YEE 54 Query: 93 PTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTF 152 T ++ ++Y + S++P G+ SSA++ +A Sbjct: 55 DTLSMAVYAS-----------LEYLNITE-ACIRCEIDSAIPEKRGMGSSAAISIAAIRA 102 Query: 153 LQQLCPDSGTIAARAQVCQQAEHSFAGMPCG------IMDQFISLMGQKGHALLIDCRSL 206 + + +AE P G + DQ I + G L Sbjct: 103 VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVG------FTEL 156 Query: 207 ETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAA 266 E L ++I ++ V +E+++ VQ + +A Sbjct: 157 EMDLSAY------LVIADTGVYGHT--------------------REAIQVVQNKGKDAL 190 Query: 267 RDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELD 326 L H +GE+ T QA A+ + D G+++ ++H L++ VS E D Sbjct: 191 PFL----------HALGEL--TQQAEIAISQKDAEGLGQILSQAHLHLKE-IGVSSLEAD 237 Query: 327 QLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEH 371 LVE AL+ G G++M+GGG GGC + L+ + E Sbjct: 238 SLVETALS-HGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEE 281 >4N3O-A nrPDB Length = 342 Score = 83.8 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 67/370 (18%), Positives = 128/370 (34%), Gaps = 47/370 (12%) Query: 26 AEPELAVSAPGRVNLIGEHTD---YNQ---GLVLPMALELMTVLVGSPRKDGLVSLLTTS 79 A + P R+ L G TD Y G VL + L R+DG + + Sbjct: 3 AMKTIRTQTPLRLGLAGGGTDINLYCDKYTGYVLNATISLYIHCTLIKREDGKIIFDSP- 61 Query: 80 EGADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGL 139 D ++ + + Y + +++ + PL FS S VP G GL Sbjct: 62 ---DTNSYCEYESKEFLGNDGKLDIFKSIYNR-IVKDFTKKPL-SFSLHTYSDVPSGSGL 116 Query: 140 SSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHAL 199 S++L V + A++ + E G+ G DQ+ + G Sbjct: 117 GGSSTLVVGVIKAFAEWLNLPLGEYEIAKLAYEIEREDLGIVGGAQDQYAATFGGFNFME 176 Query: 200 LIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVR----RRQCEEVARALGKESL 255 + + +I N + +SE R A+ + + Sbjct: 177 FYNNKR---------------VIVNPLRIKNWIASELEARTVLYFTNITREAKDIEEHKK 221 Query: 256 REVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLR 315 ++ E A H + + + AL R D+ +++ +S RS + Sbjct: 222 GKL------------GDEKSLEAMHAIKQDA--IKMKEALFRADFGTLAQILGKSWRSKK 267 Query: 316 DDYE-VSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGG 374 E VS EL+++ + A+ G Y + +G G GG ++ + + ++ +++ G Sbjct: 268 IISEIVSNDELERIYKLAID-NGAYSGKTSGAGAGGFMFFFVDPTKKYNLIKALRKEQGY 326 Query: 375 TATFYLSQAA 384 F ++ Sbjct: 327 VQDFSFTKEG 336 >2X7I-A nrPDB Length = 308 Score = 82.2 bits (201), Expect = 4e-16, Method: Composition-based stats. Identities = 61/345 (17%), Positives = 114/345 (33%), Gaps = 64/345 (18%) Query: 33 SAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQFPL 92 + G++ LIGEH A+ + P G + +L + + ++ Sbjct: 10 ESTGKIILIGEH-----------AVTFGEPAIAVPFNAGKIKVLIEALESGNYSSIK--- 55 Query: 93 PTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTF 152 + P + P + + +++P GL SSA++ VA Sbjct: 56 SDVYDGMLYDAPDHLKSLVNRFVELNNITEP-LAVTIQTNLPPSRGLGSSAAVAVAFVRA 114 Query: 153 LQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFIS----LMGQKGHALLIDCRSLET 208 S T + AE G P GI Q I + QKGHA + SL Sbjct: 115 SYDFLGKSLTKEELIEKANWAEQIAHGKPSGIDTQTIVSGKPVWFQKGHAETLKTLSL-- 172 Query: 209 SLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAARD 268 +++ ++ V+ S +A D Sbjct: 173 --------DGYMVVIDTGVKGSTR-------------------------------QAVHD 193 Query: 269 LVSK-EGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCPELDQ 327 + E + HV + +A+ + + A + E H L VS +++Q Sbjct: 194 VHKLCEDPQYMSHVKHIGKLVLRASDVIEHHKFEALADIFNECHADL-KALTVSHDKIEQ 252 Query: 328 LVEAALAVPGVYGSRMTGGGFGGCTVTLL-EASAAPHAMRHIQEH 371 L++ G ++TG G GG + L + A + ++ +++ Sbjct: 253 LMKIG-KENGAIAGKLTGAGRGGSMLLLAKDLPTAKNIVKAVEKA 296 >4UT4-A nrPDB Length = 346 Score = 76.8 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 68/353 (19%), Positives = 121/353 (34%), Gaps = 46/353 (13%) Query: 30 LAVSAPGRVNLIG------EHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGAD 83 + AP R+ L G + D G VL ++ V V ++T + + Sbjct: 6 IRARAPLRLGLAGGGTDVAPYADTFGGYVLNATIDRYAYAVIKTLTIPAVRFVSTDQQVE 65 Query: 84 EPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSA 143 + Q + PL +L A Y + Y P+ P G GL SS+ Sbjct: 66 KHQLISEPL-ELNGTLNLHK---AVYNHMIRNYNHGKPIA-LELSTFCDAPAGSGLGSSS 120 Query: 144 SLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMG-----QKGHA 198 +L V +L A AQ+ + E G+ G DQ+ + G + A Sbjct: 121 TLVVVMIKAFVELLNLPLDDYAIAQLAYRIERVDCGLAGGRQDQYSATFGGFNFMEFYAA 180 Query: 199 LLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREV 258 L L + + ++++ + V E A+ + +S V Sbjct: 181 ARTIVNPLRIKNWVLCELEASLVLFYTGV---------------SRESAKIIQDQSDNVV 225 Query: 259 QLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDY 318 K A H + + AL +GD++AF M + ++ Sbjct: 226 S-----------HKTAAIEAMHGIKREALVMK--EALLKGDFKAFVASMRLGWDNKKNSA 272 Query: 319 E-VSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQE 370 VS +D++ +AA+ G +++G G GG + + +R + E Sbjct: 273 RTVSNAHIDEIYDAAIR-AGAQAGKVSGAGGGGFMLFFVPTEKRMDLIRTLGE 324 >3K85-A nrPDB Length = 357 Score = 68.3 bits (165), Expect = 5e-12, Method: Composition-based stats. Identities = 53/341 (15%), Positives = 109/341 (31%), Gaps = 37/341 (10%) Query: 33 SAPGRVNLIG------EHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQ 86 AP R+ L G ++D GL+L + L G + + + Sbjct: 7 KAPLRLGLAGGGSDVSPYSDIYGGLILNATINLYAYCTIEETNSGRIEINAYDAQCCKSY 66 Query: 87 RLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLE 146 L +Q ++ +I+ Y P F + P G GL +S+++ Sbjct: 67 -----LSMSQLEIDGEASLIKGVYNRIIRDYRLEP-KSFKITTYNDAPAGSGLGTSSTMV 120 Query: 147 VATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSL 206 V + +++ + E G+ G DQ+ + G + + Sbjct: 121 VCILKAFIEWLSLPLGDYETSRLAYEIERKDLGLSGGKQDQYAAAFGGFNYMEFL----- 175 Query: 207 ETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEELEAA 266 + ++I N E + V G+ + E + Sbjct: 176 ----------QNDLVIVNPLKMKRWIVDEL-----ESSMVLYFTGRSRSSAAIINEQKKN 220 Query: 267 RDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYE-VSCPEL 325 + A H + + AL +GD F R++ E + + ++ P + Sbjct: 221 TSE-GNQTAIEAMHKIKQSA--IDTKLALLKGDVGEFARILGEGWENKKKMAGAITNPMI 277 Query: 326 DQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMR 366 + + A G +++G G GG + ++E + +R Sbjct: 278 QEAFDVA-TGAGAMAGKVSGAGGGGFIMFVVEPTRKEEVVR 317 >5YYS-A nrPDB Length = 949 Score = 52.6 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 67/369 (18%), Positives = 127/369 (34%), Gaps = 61/369 (16%) Query: 33 SAPGRVNLIGEHTD------YNQGLVLPMALELM----TVLVGSPRKDGLVSLLTTSEG- 81 +P R+++ G TD Y+ G V+ +A+EL + P KD + L + G Sbjct: 588 RSPVRIDMAGGWTDTPPYSLYSGGNVVNLAIELNGQPPLQVYVKPCKDFHIVLRSIDMGA 647 Query: 82 ------ADEPQRLQ-----FPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVV 130 DE Q + F +P A SL P ++ ++ G ++ Sbjct: 648 MEIVSTFDELQDYKKIGSPFSIPKAALSLAGFAPAFSAVSYASLEEQLKDFGAGIEVTLL 707 Query: 131 SSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFIS 190 +++P G GL +S+ L + C + Q E G DQ+ Sbjct: 708 AAIPAGSGLGTSSILASTVLGAINDFCGLAWDKNEICQRTLVLE-QLLTTGGGWQDQYGG 766 Query: 191 LM-------GQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQC 243 ++ + G A R L L + K L+ + + + Sbjct: 767 VLQGVKLLQTEAGFAQSPLVRWLPDHLFTHPEYKDCHLLYYTGITRT------------- 813 Query: 244 EEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAF 303 K L E+ + ++ +A H + A++RG + F Sbjct: 814 -------AKGILAEIVSSMFLNSSLHLNLLSEMKA-HALDMN-------EAIQRGSFVEF 858 Query: 304 GRLMVES-HRSLRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAP 362 GRL+ ++ ++ D + P ++ +++ G ++ G G GG + + A Sbjct: 859 GRLVGKTWEQNKALDSGTNPPAVEAIIDLIKDY--TLGYKLPGAGGGGYLYMVAKDPQAA 916 Query: 363 HAMRHIQEH 371 +R I Sbjct: 917 VRIRKILTE 925 >3HUL-A nrPDB Length = 298 Score = 51.0 bits (120), Expect = 8e-07, Method: Composition-based stats. Identities = 42/269 (15%), Positives = 79/269 (29%), Gaps = 61/269 (22%) Query: 94 TAQRSLEPGTPRWANYVK----GVIQY----------YPAAP-LPGFSAVVVSSVPLGGG 138 T +L+ G + Y++ G I + AP L V+ +P G Sbjct: 26 TLYLTLDIGAEADSWYIEHNIGGGIPHDETNVIIETALNLAPNLTPHHLVMTCDIPPARG 85 Query: 139 LSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHA 198 L SS++ VA L + + + ++ + E + ++ ++ G Sbjct: 86 LGSSSAAVVAGIELANTLAELNLSKEEKVRIAAEIEGHPDNVAPAVLGNWVVGAKLDGE- 144 Query: 199 LLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREV 258 D V P A++ + Sbjct: 145 ---DF------YVRHLFPDCALIAF----------------------------IPKAELL 167 Query: 259 QLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDY 318 E D + + +A I A A+ R D G +M + Sbjct: 168 TSESRGVLPDTLPFKEAVQA----SSIANVMIA--AILRNDMTLAGEMMERDLWHEKYRS 221 Query: 319 EVSCPELDQLVEAALAVPGVYGSRMTGGG 347 ++ P L Q+ + A G Y + ++G G Sbjct: 222 QL-VPHLAQIRDVA-KNQGAYAACLSGAG 248 >4P52-A nrPDB Length = 331 Score = 49.9 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 59/348 (16%), Positives = 101/348 (29%), Gaps = 67/348 (19%) Query: 27 EPELAVSAPGRVNLIGEHTDYNQGLVLPMALEL--MTVLVGSPRKDGLVSLLTTSEGADE 84 + + V AP V VL A++ VL+ K G+ T + Sbjct: 24 KDSIKVFAPATVA-----NVSCGFDVLGFAVDNPGDEVLLRLSDKKGVRITSITGDDGRL 78 Query: 85 PQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPL-PGFSAVVVSSVPLGGGLSSSA 143 P+ + + +++Y + G + +PLG GL SSA Sbjct: 79 PKDAEKNTVSI----------------SILRYLETLGIEQGIEIELTKKMPLGSGLGSSA 122 Query: 144 SLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMGQKGHALLIDC 203 + VA + QL + + + E G ++ G L+ Sbjct: 123 ASTVAGVYAINQLLGNKMEVKDLLPFAMEGEFLACGSAHA---DNVAPCLYGGFVLVRSY 179 Query: 204 RSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKESLREVQLEEL 263 L+ +P+ A +I +P Q ++ L K+ Sbjct: 180 DPLDVVKLPVPANLYATII-------------HPHVEVQTKDARNILPKQIA-------- 218 Query: 264 EAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCP 323 V + A L D GR M + H + V P Sbjct: 219 --------------LSQAVAQWGNVGGLVAGLLMNDTSLIGRSM-QDH-IVEPARSVLIP 262 Query: 324 ELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEH 371 D + +AAL G G ++G G L + A + + Sbjct: 263 GFDDVKKAALD-AGALGCSISGS--GPSIFALSTSQEAAQKIGQAMKK 307 >3K17-A nrPDB Length = 365 Score = 49.5 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 25/177 (14%), Positives = 50/177 (28%), Gaps = 20/177 (11%) Query: 27 EPELAVSAPGRVNLIGEHTDY-NQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEP 85 + +L V PG++ + GE+ + + A+ L + L Sbjct: 4 KNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNE--LWIPHYENPVS 61 Query: 86 QRLQFPLPTAQRSLEPGTPRWANYVKGV-----IQYYPAAPLPGFSAVVVSSVPLGGG-- 138 + L+P W + + L V+ + + G Sbjct: 62 WPIG-------GELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMVIETELIDQSGAK 114 Query: 139 --LSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFISLMG 193 L SSA+ VA L ++ + ++ + G D + G Sbjct: 115 YGLGSSAAATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCG-DIASCMYG 170 >4RPF-A nrPDB Length = 310 Score = 42.2 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 28/180 (15%), Positives = 57/180 (31%), Gaps = 23/180 (12%) Query: 125 FSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGI 184 + V+ ++P+G GL SSA VA + + C + + E +G I Sbjct: 83 VAMVLEKNMPIGSGLGSSACSVVAGLMAMNEFCGQPLDKVTLLGMMGELEGRVSG---SI 139 Query: 185 MDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASS---------- 234 ++ G L+++ + VP ++ ++ S A + Sbjct: 140 HFDNVAPCYLGGMQLILEQEGYISQDVP-GFSDWLWVMAYPGIKVSTAEARAILPAQYRR 198 Query: 235 --------EYPVRRRQCEEVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIR 286 C L + +++V E + L R+A +G + Sbjct: 199 QDCITHGRNLAGFIHACHTQQPDLAAKMMKDVIAEPYRT-QLLPGFAAARQAAQDIGALA 257 >2V2V-A nrPDB Length = 271 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 33/232 (14%), Positives = 82/232 (35%), Gaps = 13/232 (5%) Query: 54 PMALELMTVLVGS-PRKDGLVSLLTTSEGADEPQRLQFPLPTAQRSLEPGTPRWANYVKG 112 P + L ++G P + L + ++ + + ++ Y KG Sbjct: 10 PAKINLGLWVLGRLPSGYHEILTLYQEIPFYDEIYIREGVLRVETNIGIPQEENLVY-KG 68 Query: 113 VIQYYPAAPLP-GFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQ 171 + ++ + +S + ++P G GL +S + +L + ++ Sbjct: 69 LREFERITGIEINYSIFIQKNIPPGAGLGGGSSNLAVVLKKVNELLGSPLSEEELRELVG 128 Query: 172 QAEHSFAGMPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSL 231 P ++ + G KG L + + + L P+++ +++ +S Sbjct: 129 SISAD---APFFLLGKSAIGRG-KGEVLEP-VETEISGKITLVIPQVS---SSTGRVYSS 180 Query: 232 ASSEYPVRRRQCEEVARALGKESLREVQLEELEAARDLV--SKEGFRRARHV 281 E+ V EE + + + E++ + AR+L E +R ++ Sbjct: 181 LREEHFVTPEYAEEKIQRIISGEVEEIENVLGDIARELYPEINEVYRFVEYL 232 >2HKE-A nrPDB Length = 380 Score = 38.3 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 85/259 (32%), Gaps = 47/259 (18%) Query: 125 FSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGI 184 + V ++ P G++SSAS A L + + ++ A++ G C Sbjct: 98 VNIVSENNFPTAAGMASSASGYCAMSAALIRAFKSTTNVSMLARLGS-------GSACR- 149 Query: 185 MDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCE 244 S G G + P + + + + +P + C Sbjct: 150 -----SAFG--GFVIW----------NKGEKPDGS----DCVATQFVDETHWPEIQVMCA 188 Query: 245 EVARALGKESLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFG 304 V + K+ +++ L+ +R V E R A+ A++ D+ F Sbjct: 189 -VLKGAQKDVSSTKGMQQSLKTSPLMK----KRISETVPE--RMKIASRAIKARDFATFA 241 Query: 305 RLMVESHRSLRDDYEVSCPELD----------QLVEAALAVPGVYGSRMTGGGFGGCTVT 354 + + L++ + P++ +LV+A A G T C + Sbjct: 242 EIAMLESDDLQEICATTEPKITYATEDSYAMIRLVKAYNAKKGRTALAYTFDAGANCFL- 300 Query: 355 LLEASAAPHAMRHIQEHYG 373 + P A+ + EH+ Sbjct: 301 FVLKEDLPEAVAMLMEHFP 319 >3PYF-A nrPDB Length = 306 Score = 35.2 bits (79), Expect = 0.054, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 52/152 (34%), Gaps = 30/152 (19%) Query: 30 LAVSAPGRVNLI---------GEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSE 80 + V PG+VNL G H + + E+ R ++SL E Sbjct: 6 VTVRVPGKVNLYLAVGDRREDGYHELTTVFHAVSLVDEVTV------RNADVLSLELVGE 59 Query: 81 GADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLS 140 GAD+ P + + + + ++ AP S ++ S+P+ GG++ Sbjct: 60 GADQ-----LPTDERNLAWQAA--------ELMAEHVGRAP--DVSIMIDKSIPVAGGMA 104 Query: 141 SSASLEVATYTFLQQLCPDSGTIAARAQVCQQ 172 ++ A + L + + + Sbjct: 105 GGSADAAAVLVAMNSLWELNVPRRDLRMLAAR 136 >4EMD-A nrPDB Length = 318 Score = 33.7 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 21/152 (13%), Positives = 41/152 (26%), Gaps = 30/152 (19%) Query: 30 LAVSAPGRVNLI---------GEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSE 80 + V APG+VNL G H + +A ++ S Sbjct: 18 VTVRAPGKVNLYLAVGDLRDDGYHELTTVFHAVSLADDVTVRDADVL-----------SI 66 Query: 81 GADEPQRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLS 140 P + + + + AP S + +P+ GG++ Sbjct: 67 DVVGQGEGTVPTDERNLAWQAA--------ELFADHVGRAP--DVSIFINKDIPVAGGMA 116 Query: 141 SSASLEVATYTFLQQLCPDSGTIAARAQVCQQ 172 ++ A + +L + Q Sbjct: 117 GGSADAAAVLVAMNELWHAGVPRRDLHHLAAQ 148 >5WAT-A nrPDB Length = 315 Score = 33.3 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 31/165 (18%), Positives = 52/165 (31%), Gaps = 6/165 (3%) Query: 120 APLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAG 179 A +PG V +++P GL SSA+ VA L T Q+ E Sbjct: 81 AEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLADFPLTQEQIVQLSSAFEGHPDN 140 Query: 180 MPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVR 239 ++ + + + + + VPL + + V + AS+E R Sbjct: 141 AAASVLGGAVVSW---TNLSIDGKSQPQYAAVPLEVQDN--IRATALVPNFHASTEAVRR 195 Query: 240 RRQCEEVARALGKESLR-EVQLEELEAARDLVSKEGFRRARHVVG 283 E R V + L+ DL+ + R Sbjct: 196 VLPTEVTHIDARFNVSRVAVMIVALQQRPDLLWEGTRDRLHQPYR 240 >1UEK-A nrPDB Length = 275 Score = 32.1 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 37/116 (31%), Gaps = 2/116 (1%) Query: 54 PMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQF-PLPTAQRSLEPGTPRWANYVKG 112 P + L + R+DG L T RL P+ + P Y Sbjct: 6 PAKVNLGLSVRFR-REDGYHELHTLFAPFSLADRLVVEPVSSGLHFQGPYGRENLAYRAA 64 Query: 113 VIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQ 168 + A G ++ +P G GL +S LQ L P + A A+ Sbjct: 65 SLYLEAAGQPGGVRILLEKRIPEGAGLGGGSSDAAQVLLALQALYPAEVDLFALAR 120 >2OG2-A nrPDB Length = 359 Score = 31.8 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 27/239 (11%), Positives = 70/239 (29%), Gaps = 16/239 (6%) Query: 135 LGGGLSSSASLEVATYTFLQQLCPDSGTIAAR-AQVCQQAEHSFAGMPCGIMDQFISLMG 193 + G L S + ++ A + ++ + + A G+ G + + Sbjct: 119 MSGKLKSGSEIKDALKESVLEMLAKKNSKTELQLGFRKPAVIMIVGVNGGGKTTSLGKLA 178 Query: 194 QKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKE 253 + + K+ + ++ + E R CE V K Sbjct: 179 HR---------------LKNEGTKVLMAAGDTFRAAASDQLEIWAERTGCEIVVAEGDKA 223 Query: 254 SLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRS 313 V + ++ ++ + + A ++ + E Sbjct: 224 KAATVLSKAVKRGKEEGYDVVLCDTSGRLHTNYSLMEELIACKKAVGKIVSGAPNEILLV 283 Query: 314 LRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHY 372 L + ++ + + + G+ +++ G GGC V+++E P + E Sbjct: 284 LDGNTGLNMLPQAREFNEVVGITGLILTKLDGSARGGCVVSVVEELGIPVKFIGVGEAV 342 >5L3R-B nrPDB Length = 293 Score = 31.8 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 27/239 (11%), Positives = 70/239 (29%), Gaps = 16/239 (6%) Query: 135 LGGGLSSSASLEVATYTFLQQLCPDSGTIAAR-AQVCQQAEHSFAGMPCGIMDQFISLMG 193 + G L S + ++ A + ++ + + A G+ G + + Sbjct: 53 MSGKLKSGSEIKDALKESVLEMLAKKNSKTELQLGFRKPAVIMIVGVNGGGKTTSLGKLA 112 Query: 194 QKGHALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLASSEYPVRRRQCEEVARALGKE 253 + + K+ + ++ + E R CE V K Sbjct: 113 HR---------------LKNEGTKVLMAAGDTFRAAASDQLEIWAERTGCEIVVAEGDKA 157 Query: 254 SLREVQLEELEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRS 313 V + ++ ++ + + A ++ + E Sbjct: 158 KAATVLSKAVKRGKEEGYDVVLCDTSGRLHTNYSLMEELIACKKAVGKIVSGAPNEILLV 217 Query: 314 LRDDYEVSCPELDQLVEAALAVPGVYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHY 372 L + ++ + + + G+ +++ G GGC V+++E P + E Sbjct: 218 LDGNTGLNMLPQAREFNEVVGITGLILTKLDGSARGGCVVSVVEELGIPVKFIGVGEAV 276 >2WW4-A nrPDB Length = 283 Score = 31.8 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 47/142 (33%), Gaps = 18/142 (12%) Query: 34 APGRVNLI----GEHTD-YNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRL 88 +P ++NL G+ D Y+ L L+ + R DG + LLT EG + L Sbjct: 7 SPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNL 66 Query: 89 QFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASLEVA 148 + R G + + +P+GGGL +S Sbjct: 67 IVRAARLLMKTAADSGR-------------LPTGSGANISIDKRLPMGGGLGGGSSNAAT 113 Query: 149 TYTFLQQLCPDSGTIAARAQVC 170 L L ++ A++ Sbjct: 114 VLVALNHLWQCGLSMDELAEMG 135 >3J6B-S nrPDB Length = 258 Score = 29.1 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 27/72 (37%), Gaps = 1/72 (1%) Query: 248 RALGKESLREVQLEELEAARDLVS-KEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRL 306 R + + + ++ A+ L KE + + GE Q+ L G + FG Sbjct: 25 RLIETRKIAKQPNYQVGDAKPLHMPKERKKFPDYKYGESNIFKQSNKGLYGGSFVQFGNN 84 Query: 307 MVESHRSLRDDY 318 + ES R + Sbjct: 85 ISESKAKTRKKW 96 >1H73-A nrPDB Length = 296 Score = 29.1 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 26/161 (16%), Positives = 51/161 (31%), Gaps = 14/161 (8%) Query: 86 QRLQFPLPTAQRSLEPGTPRWANYVKGVIQYYPAAPLPGFSAVVVSSVPLGGGLSSSASL 145 + + + +P K +I + G + V G GL SSA+ Sbjct: 40 KEIIIEVDDKNIPTDPDKNVAGIVAKKMIDDFNIG--KGVKITIKKGVKAGSGLGSSAAS 97 Query: 146 EVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAGMPCGIMDQFI-SLMGQKGHALLIDCR 204 T + +L + E + +G D ++ G G ++ + Sbjct: 98 SAGTAYAINELFKLNLDKLKLVDYASYGELASSGAKHA--DNVAPAIFG--GFTMVTNYE 153 Query: 205 SLETSLVPLSDPKLAVLIT------NSNVRHSLASSEYPVR 239 LE +P+ KL +LI N+ + ++ Sbjct: 154 PLEVLHIPIDF-KLDILIAIPNISINTKEAREILPKAVGLK 193 >5WAS-A nrPDB Length = 185 Score = 28.7 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 32/98 (32%), Gaps = 3/98 (3%) Query: 120 APLPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAARAQVCQQAEHSFAG 179 A +PG V +++P GL SSA+ VA L T Q+ E Sbjct: 81 AEVPGLRVVCHNNIPQSRGLGSSAAAAVAGVAAANGLADFPLTQEQIVQLSSAFEGHPDN 140 Query: 180 MPCGIMDQFISLMGQKGHALLIDCRSLETSLVPLSDPK 217 ++ + + + + + VPL Sbjct: 141 AAASVLGGAVVSW---TNLSIDGKSQPQYAAVPLEVQD 175 >3KAK-A nrPDB Length = 499 Score = 28.3 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 34/104 (32%), Gaps = 12/104 (11%) Query: 222 ITNSNVRHSLASSEYPV----RRRQC-EEVARALGKESLREVQLEELEAARDLVSKEGFR 276 I N V ++ R + E +R L S L+ + + G Sbjct: 99 IFNELVDRVSLDGKFLQESLSRTKNADEFTSRLLDIHSKM------LQINKKEDIRMGIV 152 Query: 277 RARHVVGEIRR-TAQAAAALRRGDYRAFGRLMVESHRSLRDDYE 319 R+ +++ E + Q + G LM H+SL Y Sbjct: 153 RSDYMIDEKTKSLLQIEMNTISTSFALIGCLMTGLHKSLLSQYG 196 >1KWK-A nrPDB Length = 645 Score = 27.9 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 14/49 (28%) Query: 275 FRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDDYEVSCP 323 + + V E R A R G A ++ D CP Sbjct: 105 YCFSSPVYREEARRIVTLLAERYGGLEAVAGFQTDNEYGCHDTVRCYCP 153 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.118 0.278 Lambda K H 0.267 0.0368 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,355,887 Number of Sequences: 36641 Number of extensions: 385917 Number of successful extensions: 1336 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 1177 Number of HSP's gapped (non-prelim): 92 length of query: 392 length of database: 10,336,785 effective HSP length: 99 effective length of query: 293 effective length of database: 6,709,326 effective search space: 1965832518 effective search space used: 1965832518 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.9 bits)