BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P51553 (393 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5GRH-B nrPDB 734 0.0 3BLX-A nrPDB 347 6e-96 5YVT-A nrPDB 283 7e-77 3BLV-B nrPDB 250 7e-67 2D1C-A nrPDB 216 1e-56 3ASJ-A nrPDB 194 4e-50 4Y1P-A nrPDB 193 1e-49 1WPW-A nrPDB 189 1e-48 5HN5-A nrPDB 153 1e-37 3TY3-A nrPDB 149 3e-36 2E5M-A nrPDB 139 3e-33 1IDM-A nrPDB 138 5e-33 2IV0-A nrPDB 134 7e-32 1XAD-A nrPDB 132 2e-31 3U1H-A nrPDB 132 3e-31 1XGV-A nrPDB 128 4e-30 3VMK-A nrPDB 126 2e-29 1A05-A nrPDB 125 3e-29 3VML-A nrPDB 124 5e-29 2G4O-A nrPDB 124 9e-29 1V5B-A nrPDB 123 1e-28 3VMJ-A nrPDB 122 2e-28 1VLC-A nrPDB 122 3e-28 1CNZ-A nrPDB 122 4e-28 3FMX-X nrPDB 117 1e-26 5J32-A nrPDB 116 1e-26 1CM7-A nrPDB 115 4e-26 2D4V-A nrPDB 114 6e-26 1HQS-A nrPDB 114 6e-26 5M2E-A nrPDB 107 8e-24 6C0E-A nrPDB 105 3e-23 1AI3-A nrPDB 103 1e-22 3DMS-A nrPDB 103 1e-22 4IWH-A nrPDB 98 6e-21 3UDO-A nrPDB 89 4e-18 2C07-A nrPDB 33 0.17 1UPX-A nrPDB 31 1.0 4ZP1-A nrPDB 29 3.6 4KPO-A nrPDB 29 4.4 3PMN-A nrPDB 28 7.8 >5GRH-B nrPDB Length = 354 Score = 734 bits (1894), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 40 FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED 99 FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED Sbjct: 1 FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED 60 Query: 100 IRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHK 159 IRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHK Sbjct: 61 IRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHK 120 Query: 160 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV 219 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV Sbjct: 121 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV 180 Query: 220 HKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI 279 HKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI Sbjct: 181 HKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI 240 Query: 280 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL 339 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL Sbjct: 241 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL 300 Query: 340 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA 393 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA Sbjct: 301 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA 354 >3BLX-A nrPDB Length = 349 Score = 347 bits (889), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 170/344 (49%), Positives = 238/344 (69%), Gaps = 4/344 (1%) Query: 41 SEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI 100 +E+T+P KYGGR TVT+IPGDG+G E+ V+++F +P+D+E +++ +E + Sbjct: 6 AERTLP--KKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGV 63 Query: 101 RNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKD 160 A+ +++RN++ LKG T + H S N LR LD+YANV KSL GV TR D Sbjct: 64 YEAVESLKRNKIGLKGLWHTPAD-QTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPD 122 Query: 161 IDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVH 220 ID++++RENTEGE+S LEHESV GVVESLK++T+ K+ RIA +AF A++ RK VTAVH Sbjct: 123 IDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVH 182 Query: 221 KANIMKLGDGLFLQCCREVAAR-YPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI 279 KANIMKLGDGLF E+ + YP I ++IVDN +MQ V++P QFDV+V P++YG I Sbjct: 183 KANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTI 242 Query: 280 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL 339 + N+ A L+GGPGLVAGAN+G YAVFE +R+ G I +N+ANPTA +L+S +ML+HL Sbjct: 243 LGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHL 302 Query: 340 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 L+ YAT I KAV ++ T DIGG +T++ ++I + Sbjct: 303 GLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKL 346 >5YVT-A nrPDB Length = 339 Score = 283 bits (725), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 149/341 (43%), Positives = 216/341 (63%), Gaps = 8/341 (2%) Query: 52 GGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS----NADEEDIRNAIMAI 107 GG TVT+IPGDGIGPE+ V +F A P+ +EE +V++ A ++ Sbjct: 2 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 61 Query: 108 RRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVR 167 +N++ LKG ++T + H S N +LR + DLYANV C S+ G T + D++I+ +R Sbjct: 62 DKNKMGLKGPLKTP--IAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIR 119 Query: 168 ENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKL 227 ENTEGEYS +EH V GVV+S+K+IT+ S RIAE+AF+ A+ + R VTAVHKANIM++ Sbjct: 120 ENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRM 179 Query: 228 GDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGL 287 DGLFLQ CREVA I F M +D + +V P QFDV+VMPNLYG+I++++CAGL Sbjct: 180 SDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGL 239 Query: 288 VGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYAT 346 +GG G+ N G + A+FE+ T IA K++ANPTA LL++ MML H+ L +A Sbjct: 240 IGGLGVTPSGNIGANGVAIFES-VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAA 298 Query: 347 SIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVIN 387 I A A++ + T D+GG S+ +++ R ++ ++ Sbjct: 299 RIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD 339 >3BLV-B nrPDB Length = 354 Score = 250 bits (639), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 139/339 (41%), Positives = 213/339 (62%), Gaps = 12/339 (3%) Query: 53 GRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS---NADEEDIRNAIMAIRR 109 G++TV+ I GDGIGPE+ VK +F A VP+++E VS N A+ +I + Sbjct: 20 GKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITK 79 Query: 110 NRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVREN 169 N VALKG + T + H+S N LR + L+ANV KS+ G T ++++D++++REN Sbjct: 80 NLVALKGPLATP--IGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIREN 137 Query: 170 TEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGD 229 TEGEYS +EH GVV+S+K+IT+ S R+ YAF+ A+ GR +V VHK+ I +L D Sbjct: 138 TEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLAD 197 Query: 230 GLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD--VMVMPNLYGNIVNNVCAGL 287 GLF+ +E++ YP +T E ++DN+ +++V+ P + V V PNLYG+I++++ +GL Sbjct: 198 GLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGL 257 Query: 288 VGGP-GLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYAT 346 G GL AN GH ++FE A + IA ++ ANPTA LL+S MML+H+ L ++A Sbjct: 258 SAGSLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHAD 316 Query: 347 SIRKAVLASMDN--ENMHTPDIGGQGTTSEAIQDVIRHI 383 I+ AVL+++ + EN T D+ G TTS + VI+ + Sbjct: 317 QIQNAVLSTIASGPEN-RTGDLAGTATTSSFTEAVIKRL 354 >2D1C-A nrPDB Length = 496 Score = 216 bits (550), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 127/341 (37%), Positives = 193/341 (56%), Gaps = 13/341 (3%) Query: 53 GRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI-----RNAIMAI 107 GR +T+IPGDGIGPE + V A P+ +E ++ I + I +I Sbjct: 18 GRKLITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESI 77 Query: 108 RRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRH--KDIDILI 165 R+ RV LKG +ET KS N LR + YANV + P V T + + ID+++ Sbjct: 78 RKTRVVLKGPLETPVGY--GEKSANVTLRKLFETYANVRPVREFPNVPTPYAGRGIDLVV 135 Query: 166 VRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIM 225 VREN E Y+ +EH V ++LK+I+ S +I +AF+LA+ GRKKV K+NIM Sbjct: 136 VRENVEDLYAGIEHMQTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIM 195 Query: 226 KLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCA 285 KL +G + +VA YP I ++IVDN QLV RP+QF+V+V N+ G+I++++ + Sbjct: 196 KLAEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTS 255 Query: 286 GLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYA 345 GL+GG G AN G+ A+FE A + A KN+ NPTA LL++ MML +L+ + A Sbjct: 256 GLIGGLGFAPSANIGNEVAIFE-AVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEFATA 314 Query: 346 TSIRKAVLASMDNENMHTPDIGGQ---GTTSEAIQDVIRHI 383 I A+L +++ + T D+ G T+E + +I+++ Sbjct: 315 DLIENALLYTLEEGRVLTGDVVGYDRGAKTTEYTEAIIQNL 355 >3ASJ-A nrPDB Length = 334 Score = 194 bits (494), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 122/334 (36%), Positives = 173/334 (51%), Gaps = 8/334 (2%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED----IRNAIMAIRRN 110 + + +I GDGIG E++ + V +P++F E E + I Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSC 62 Query: 111 RVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENT 170 L G + P LR LDLYANV KS P V +D++IVRENT Sbjct: 63 HATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRP-VPGSRPGVDLVIVRENT 121 Query: 171 EGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDG 230 EG Y E + V + +I+K S RI A ++A+ RK + HKAN++ L G Sbjct: 122 EGLYVEQERRYL-DVAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQG 180 Query: 231 LFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGG 290 LFL +EVA +P + +++IVDN MQLV RP++FDV+V NL G+I++++ AGLVGG Sbjct: 181 LFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGG 240 Query: 291 PGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRK 350 GL N G AVFE + IA K IANPTA +L++ MMLD+L A + K Sbjct: 241 LGLAPSGNIGDTTAVFEP-VHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEK 299 Query: 351 AVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIR 384 AV ++ TPD+GG TT + V+ ++ Sbjct: 300 AVDLVLER-GPRTPDLGGDATTEAFTEAVVEALK 332 >4Y1P-A nrPDB Length = 337 Score = 193 bits (490), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 124/336 (36%), Positives = 179/336 (53%), Gaps = 27/336 (8%) Query: 57 VTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNADEE--DI--RNAIMAIR 108 V +I GDGIGPE++ K++ +P+++ EV + D ++++ I Sbjct: 5 VALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRVIE 64 Query: 109 RNRVALKGNI-ETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVR 167 + + LKG + ET ++ LR DLYAN+ KSLPG+ + D+DIL+VR Sbjct: 65 KADMILKGPVGETAADVVVK-------LRLMYDLYANLRPAKSLPGLENKFGDVDILVVR 117 Query: 168 ENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKL 227 ENTE Y LEH GV +K+IT+A S RIA+ A A +KKV VHK+N+M++ Sbjct: 118 ENTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALRR-KKKVVCVHKSNVMRI 176 Query: 228 GDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGL 287 DGLF + CR V ++ + M VD LV PQ FDV+V N YG+I+++ + Sbjct: 177 TDGLFAESCRNVLK--GKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAGQI 234 Query: 288 VGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL-------K 340 G G+ AN G ++FE IA KNIANPTA LL+ MMLD + + Sbjct: 235 AGSLGISPSANIGDRKSLFE-PVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDIR 293 Query: 341 LHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAI 376 ++ A S+R A+ + TPD+GG TT E I Sbjct: 294 YNNAAKSLRDAIYSVYSEGKYLTPDVGGSSTTDEMI 329 >1WPW-A nrPDB Length = 336 Score = 189 bits (481), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 120/343 (34%), Positives = 177/343 (51%), Gaps = 31/343 (9%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHA----CVPVDFEEVHVSSNA----DEEDIRNAIMA 106 TV +I GDGIGPE++ K + +P+++ EV A E ++++ Sbjct: 2 FTVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKI 61 Query: 107 IRRNRVALKGNIETNHNLPPSHKSRNNI---LRTSLDLYANVIHCKSLPGVVTRHKDIDI 163 I + + LKG P +S ++ LR D+YAN+ KS+PG+ T++ ++DI Sbjct: 62 IDKADIILKG---------PVGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGNVDI 112 Query: 164 LIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKAN 223 LIVRENTE Y EH GV +KIIT+ S RIA+ A RKKVT VHKAN Sbjct: 113 LIVRENTEDLYKGFEHIVSDGVAVGMKIITRFASERIAKVGLNFALRR-RKKVTCVHKAN 171 Query: 224 IMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNV 283 +M++ DGLF + CR V ++ + M VD LV PQ FDV+V N+YG+I+++ Sbjct: 172 VMRITDGLFAEACRSVLK--GKVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDE 229 Query: 284 CAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL---- 339 + + G G+ AN G A+FE IA KNI NPTA LL+ MM + + Sbjct: 230 ASQIAGSLGIAPSANIGDKKALFEP-VHGAAFDIAGKNIGNPTAFLLSVSMMYERMYELS 288 Query: 340 ---KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV 379 + + ++ A+ TPD+GG TT + I ++ Sbjct: 289 NDDRYIKASRALENAIYLVYKERKALTPDVGGNATTDDLINEI 331 >5HN5-A nrPDB Length = 353 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 114/337 (33%), Positives = 175/337 (51%), Gaps = 27/337 (8%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVH--------VSSNADEEDIRNAIMA 106 + V +IPGDGIGPE++ V + V FE S EED+ Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAVTGRVRFEYYEGGVDVFQECGSPIREEDLEE---- 57 Query: 107 IRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIV 166 IRR+ L G T +LP ++S LR L LYAN+ + +P + T +I+IV Sbjct: 58 IRRSDAVLFGATTTPFDLP-GYRSLILTLRKELGLYANL---RIIPDLRTGR---EIVIV 110 Query: 167 RENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMK 226 REN+EG Y + V G +++IT+ + RIA +A + A+ G +T VHKAN++ Sbjct: 111 RENSEGLYFGI-GAVVNGRAVDVRLITREGAERIARFAVEQAKARG-SFITFVHKANVLT 168 Query: 227 LGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAG 286 GD F + REVA + + I+D+ T++LV P + V++ NL+G+I++++ Sbjct: 169 -GDKFFRRIVREVAGE-EGVEVRDAIIDSFTIKLVRNPWEHGVILSENLFGDILSDLATV 226 Query: 287 LVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYAT 346 G G+V NYG A+FE + IA K IANP +L+ M+LD+L L + Sbjct: 227 HAGSIGIVPSGNYGDGIALFE-PVHGSAPDIAGKGIANPIGAILSGAMLLDYLGLD--GS 283 Query: 347 SIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 IR AV + N + TPD+GG+ T + ++ +I I Sbjct: 284 LIRAAVRGYVVNGEL-TPDMGGRARTEDVVRGIIGEI 319 >3TY3-A nrPDB Length = 366 Score = 149 bits (375), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 111/358 (31%), Positives = 176/358 (49%), Gaps = 31/358 (8%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRV- 112 R + +IP DGIG E++ + + + + + +A A+ V Sbjct: 10 RIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTVE 69 Query: 113 --------ALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDIL 164 AL G +++ + + S LR + LYANV KSL G + K +D++ Sbjct: 70 RLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDG--AKGKPVDLV 127 Query: 165 IVRENTEGEYSSLEH--ESVAG--VVESLKIITKAKSLRIAEYAFKLAQ------ESG-- 212 IVRENTE Y E ++ G V E+++ I++ S +I + AF++A+ ESG Sbjct: 128 IVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRESGTY 187 Query: 213 ----RKKVTAVHKANIMKLGDGLFLQCCREVAA---RYPQITFENMIVDNTTMQLVSRPQ 265 + VT +HK+N+M + DGLF + CR + Y I + IVD+ +L P+ Sbjct: 188 SIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFREPE 247 Query: 266 QFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANP 325 FDV+V PNLYG+I+++ A L+G GLV AN G + + E + IA + IANP Sbjct: 248 CFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFVMSE-PVHGSAPDIAGRGIANP 306 Query: 326 TATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 AT + +ML+ + A I AV + + TPD+GG+ T+E V+ +I Sbjct: 307 VATFRSVALMLEFMGHQDAAADIYTAVDKVLTEGKVLTPDLGGKSGTNEITDAVLANI 364 >2E5M-A nrPDB Length = 409 Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 102/353 (28%), Positives = 165/353 (46%), Gaps = 59/353 (16%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHACV-------PVDFEEVHVSSNAD----EEDIRN 102 + + I GDGIGPE+ V A + + EV+ A+ + + Sbjct: 24 KPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSREIKWLEVYAGEKAEKLVNDRFPKE 83 Query: 103 AIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVT--RHKD 160 + + RV LKG +ET + KS N +R LDLYAN+ K + G+ + +H + Sbjct: 84 TQEMLLKYRVVLKGPLETP--IGKGWKSVNVAIRLMLDLYANIRPVKYIEGLESPLKHPE 141 Query: 161 -IDILIVRENTEGEYSSLEH----------------------ESVAGVVESLKIITKAKS 197 +D++I RENT+ Y +E+ E G+ +K+++K K+ Sbjct: 142 KVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKELKVEIEDDTGI--GIKVMSKYKT 199 Query: 198 LRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAR--------------- 242 RI A + A E RKKVT +HK N+MK +G F + EVA + Sbjct: 200 QRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYEVALKEYRDFIVTEEEINQG 259 Query: 243 ---YPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANY 299 +I + I DN Q++ RP+++D+++ PN+ G+ +++ L+G G++ GAN Sbjct: 260 KPDQGKIILNDRIADNMFQQIIIRPEEYDIILAPNVNGDYISDAAGALIGNIGMLGGANI 319 Query: 300 GHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAV 352 G +FE A T A KN+ANPT + A +ML + + A I KA+ Sbjct: 320 GDEGGMFE-AIHGTAPKYAGKNVANPTGIIKAGELMLRWMGWNEAADLIEKAI 371 >1IDM-A nrPDB Length = 343 Score = 138 bits (347), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 103/348 (29%), Positives = 160/348 (45%), Gaps = 29/348 (8%) Query: 57 VTMIPGDGIGPELMLHVKSVFR-----------HACVPVDFEEVHVSSNADEEDIRNAIM 105 V ++PGDGIGPE+ V R + P + E R + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGV- 61 Query: 106 AIRRNRVALKGNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRH----- 158 L G++ S + +L R S DL+AN+ K PG+ Sbjct: 62 --EEAEAVLLGSVGGPKWGTGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEE 119 Query: 159 --KDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKV 216 + +D+LIVRE T G Y + + +K + R+A AF+ A++ RK V Sbjct: 120 IARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKHV 178 Query: 217 TAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLY 276 +V KAN++++G+ + + EV YP + E+ VD M LV P +FDV+V N++ Sbjct: 179 VSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIF 237 Query: 277 GNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMML 336 G+I++++ + L G GL+ A+ G VFE + IA K IANPTA +L++ MML Sbjct: 238 GDILSDLASVLPGSLGLLPSASLGRGTPVFEP-VHGSAPDIAGKGIANPTAAILSAAMML 296 Query: 337 DH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 +H L A + AV ++ PD+GG T V+RH+ Sbjct: 297 EHAFGLVELARKVEDAVAKAL--LETPPPDLGGSAGTEAFTATVLRHL 342 >2IV0-A nrPDB Length = 412 Score = 134 bits (337), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 102/350 (29%), Positives = 160/350 (45%), Gaps = 59/350 (16%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIR--------NAIMAIR 108 + GDGIG +++ V A + E V A E+ + + + AI+ Sbjct: 30 IPYFEGDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNYLPDDTLNAIK 89 Query: 109 RNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANV---IHCKSLPGVVTRHKDIDILI 165 RVALKG + T + ++S N +R LDLYANV + K +P + + ++ +I Sbjct: 90 EFRVALKGPLTTP--VGGGYRSLNVTIRQVLDLYANVRPVYYLKGVPSPIKHPEKVNFVI 147 Query: 166 VRENTEGEYSSLEHESVAGVVESLKIITKAK----------------------SLRIAEY 203 RENTE Y+ +E G E+LK+I K + R+ Sbjct: 148 FRENTEDVYAGIEWPR--GSEEALKLIRFLKNEFGVTIREDSGIGIKPISEFATKRLVRM 205 Query: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA-------------------ARYP 244 A + A E+ RK VT VHK NIMK +G F EVA + P Sbjct: 206 AIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQEFGEYCITEDELWDKYGGKQP 265 Query: 245 Q--ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHV 302 + I ++ I DN Q+++R ++DV+ +PNL G+ +++ A L+GG G+ G+N G Sbjct: 266 EGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGDYLSDAAAALIGGLGIAPGSNIGDG 325 Query: 303 YAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAV 352 VFE + A +N NPTA +L +M +++ + I+KAV Sbjct: 326 IGVFE-PVHGSAPKYAGQNKVNPTAEILTGALMFEYIGWKDASEMIKKAV 374 >1XAD-A nrPDB Length = 345 Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 103/348 (29%), Positives = 160/348 (45%), Gaps = 27/348 (7%) Query: 57 VTMIPGDGIGPELMLHVKSVFR-----------HACVPVDFEEVHVSSNADEEDIRNAIM 105 V ++PGDGIGPE+ V R + P + E R + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKGVE 62 Query: 106 AIRRNRVALKGNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCK---SLPGVVTRHKD 160 + G + + N P + +L R LDL+AN+ K SL K+ Sbjct: 63 EAEAVLLGSVGGPKWDQN-PRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASPLKKE 121 Query: 161 ----IDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKV 216 +D +IVRE T G Y + + +K + R+A AF+ A++ RK V Sbjct: 122 YIDNVDFVIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKHV 180 Query: 217 TAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLY 276 +V KAN++++G+ + + EV YP + E+ VD M LV P +FDV+V N++ Sbjct: 181 VSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIF 239 Query: 277 GNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMML 336 G+I++++ + L G GL+ A+ G VFE + IA K IANPTA +L++ MML Sbjct: 240 GDILSDLASVLPGSLGLLPSASLGRGTPVFEP-VHGSAPDIAGKGIANPTAAILSAAMML 298 Query: 337 DH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 +H L A + AV ++ PD+GG T V+RH+ Sbjct: 299 EHAFGLVELARKVEDAVAKAL--LETPPPDLGGSAGTEAFTATVLRHL 344 >3U1H-A nrPDB Length = 390 Score = 132 bits (332), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 110/356 (30%), Positives = 178/356 (50%), Gaps = 33/356 (9%) Query: 54 RHTVTMIPGDGIGPELMLH----VKSVFRHACVPVDFEEVHVSSNADEE---DIRNAIMA 106 + + ++PGDGIGPE+M +K+V +FE + A +E + + Sbjct: 23 KKKIAVLPGDGIGPEVMEAAIEVLKAVAERFGHEFEFEYGLIGGAAIDEAGTPLPEETLD 82 Query: 107 IRRNRVALK----GNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCK---SLPGVVTR 157 + R A+ G + + N P + +L R LDL+AN+ K SL Sbjct: 83 VCRGSDAILLGAVGGPKWDQN-PSELRPEKGLLGIRKGLDLFANLRPVKVYDSLADASPL 141 Query: 158 HKDI----DILIVRENTEGEY----SSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQ 209 K++ D++IVRE T G Y S E V++L + T+ + RI AF+LA Sbjct: 142 KKEVIEGVDLVIVRELTGGLYFGEPSERYEEGEEAAVDTL-LYTREEIERIIRKAFELAL 200 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 + +KKVT+V KAN+++ L+ + EVA YP + E+M+VDN MQL+ P+QFDV Sbjct: 201 -TRKKKVTSVDKANVLE-SSRLWREVAEEVAKEYPDVELEHMLVDNAAMQLIRNPRQFDV 258 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATL 329 +V N++G+I+++ + + G G++ A+ + IA K IANP AT+ Sbjct: 259 IVTENMFGDILSDEASMITGSLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPLATI 318 Query: 330 LASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI---GGQGTTSEAIQDVIR 381 L++ MML + L A +I KAV + E T DI GG+ ++ + D ++ Sbjct: 319 LSAAMMLRYSFGLEEEAKAIEKAVEKVL-AEGYRTADIAKPGGKYVSTTEMTDEVK 373 >1XGV-A nrPDB Length = 435 Score = 128 bits (322), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 115/390 (29%), Positives = 183/390 (46%), Gaps = 69/390 (17%) Query: 57 VTMIPGDGIGPELM--------LHVKSVFRHACVPVDFEEV--HVSSNADEEDIRNAIM- 105 V I GDG+GPE++ VK V+ + V +E + H++ E + A + Sbjct: 38 VAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIVWWELLAGHLAREKCGELLPKATLE 97 Query: 106 AIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANV--IHCKSLPGVVTRHKDIDI 163 IR RVALKG +ET + ++S N +R +LDLYAN+ + P +D+ Sbjct: 98 GIRLARVALKGPLETP--VGTGYRSLNVAIRQALDLYANIRPVRYYGQPAPHKYADRVDM 155 Query: 164 LIVRENTEGEYSSLE--HESV--------------------AGVVESLKIITKAKSLRIA 201 +I RENTE Y+ +E H+S AG+ +K I++ + R+ Sbjct: 156 VIFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIREDAGI--GVKPISRFATRRLM 213 Query: 202 EYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA---------------ARYP-- 244 E A + A +G VT +HK NIMK +G F++ EVA +Y Sbjct: 214 ERALEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYEVALEKFREHVVTEQEVQEKYGGV 273 Query: 245 ----QITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG 300 +I + I DN Q+++RP + V+V PNL G+ +++ + LVGG G+ AG N G Sbjct: 274 RPEGKILVNDRIADNMLQQIITRPWDYQVIVAPNLNGDYISDAASALVGGIGMAAGMNMG 333 Query: 301 HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATS-----IRKAVLAS 355 AV E T A K++ NP+A +L++ +++ S IRKAV + Sbjct: 334 DGIAVAEP-VHGTAPKYAGKDLINPSAEILSASLLIGEFMGWREVKSIVEYAIRKAVQSK 392 Query: 356 MDNENM--HTPDIGGQGTTSEAIQDVIRHI 383 +++ H P + TSE + +I +I Sbjct: 393 KVTQDLARHMPGVQPL-RTSEYTETLIAYI 421 >3VMK-A nrPDB Length = 375 Score = 126 bits (316), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 103/333 (30%), Positives = 163/333 (48%), Gaps = 34/333 (10%) Query: 55 HTVTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNADE-------EDIRNA 103 + + ++ GDGIGPE+M + V + + +++ E V A + E Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRFDLSIEYSEYDVGGAAIDNHGCPLPEATLKG 73 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV----- 155 A G + H LPP+ + L R +L+ N+ K PG+ Sbjct: 74 CEAADAVLFGSVGGPKWEH-LPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPL 132 Query: 156 ---TRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKII-----TKAKSLRIAEYAFKL 207 K DIL VRE T G Y + + G E+ + ++ + RIA+ AF+ Sbjct: 133 RSDISEKGFDILCVRELTGGIYFG-KPKGRQGEGENEEAFDTMRYSRKEIRRIAKIAFES 191 Query: 208 AQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQF 267 AQ RKKVT+V KAN++ L+ + EVA YP + E++ +DN TMQL+ RP +F Sbjct: 192 AQ-GRRKKVTSVDKANVLAC-SVLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEF 249 Query: 268 DVMVMPNLYGNIVNNVCAGLVGGPGLVAGANY-GHVYAVFETATRNTGKSIANKNIANPT 326 DVM+ NL+G+IV++ A L G GL+A + + ++E A + IA + IANP Sbjct: 250 DVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAG-GSAPDIAGQGIANPV 308 Query: 327 ATLLASCMMLDH-LKLHSYATSIRKAVLASMDN 358 A +L++ ++L H LKL A +I AV ++ + Sbjct: 309 AQILSAALLLRHSLKLEDAALAIEAAVSKALSD 341 >1A05-A nrPDB Length = 358 Score = 125 bits (314), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 98/339 (28%), Positives = 161/339 (47%), Gaps = 28/339 (8%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHA---------CVPVDFEEVHVSSNADEEDIRNAIMAI 107 + + GDGIGPE++ + V C + ++ D + +A+ Sbjct: 4 IAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAM 63 Query: 108 RRNRVALKGNIETNHN-LPPSHKSRNNILR--TSLDLYANVIHCKSLPGVVTRH------ 158 + V L + PP+ + +LR LDLYAN+ + P ++ Sbjct: 64 AADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPEL 123 Query: 159 -KDIDILIVRENTEGEYSSLEH--ESVAGVVESLK--IITKAKSLRIAEYAFKLAQESGR 213 +D+DIL+VRE T Y E + G + + + RIA AF+ AQ R Sbjct: 124 VRDVDILVVRELTGDIYFGQPRGLEVIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQGR-R 182 Query: 214 KKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMP 273 K++ +V KAN+++ L+ + EVA YP + +M VDN MQL+ P QFDV++ Sbjct: 183 KQLCSVDKANVLETTR-LWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTG 241 Query: 274 NLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASC 333 N++G+I+++ + L G G++ A+ G A++E + IA ++ ANP AT+L+ Sbjct: 242 NMFGDILSDEASQLTGSIGMLPSASLGEGRAMYEP-IHGSAPDIAGQDKANPLATILSVA 300 Query: 334 MMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGT 371 MML H L +A + AV +D + + T DI GT Sbjct: 301 MMLRHSLNAEPWAQRVEAAVQRVLD-QGLRTADIAAPGT 338 >3VML-A nrPDB Length = 375 Score = 124 bits (312), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 103/333 (30%), Positives = 164/333 (49%), Gaps = 34/333 (10%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFR----HACVPVDFEEVHVSSNADE-------EDIRNA 103 + + ++ GDGIGPE+M + V + + +++ E V A + E Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV----- 155 A G + H LPP+ + L R +L+ N+ K PG+ Sbjct: 74 CEAADAVLFGSVGGPKWEH-LPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPL 132 Query: 156 ---TRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKII-----TKAKSLRIAEYAFKL 207 K DIL VRE T G Y + + G E+ + ++ + RIA+ AF+ Sbjct: 133 RSDISEKGFDILCVRELTGGIYFG-KPKGRQGEGENEEAFDTMRYSRKEIRRIAKIAFES 191 Query: 208 AQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQF 267 AQ RKKVT+V KAN++ L+ + EVA YP + E++ +DN TMQL+ RP +F Sbjct: 192 AQ-GRRKKVTSVDKANVLACSV-LWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEF 249 Query: 268 DVMVMPNLYGNIVNNVCAGLVGGPGLVAGANY-GHVYAVFETATRNTGKSIANKNIANPT 326 DVM+ NL+G+IV++ A L G GL+A + + ++E A + IA + IANP Sbjct: 250 DVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAG-GSAPDIAGQGIANPV 308 Query: 327 ATLLASCMMLDH-LKLHSYATSIRKAVLASMDN 358 A +L++ ++L H LKL A +I AV ++++ Sbjct: 309 AQILSAALLLRHSLKLEDAALAIEAAVSKALNS 341 >2G4O-A nrPDB Length = 337 Score = 124 bits (310), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 99/330 (30%), Positives = 162/330 (49%), Gaps = 22/330 (6%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHACVP----VDFEEVHVSSNADEEDIRNAIMAIRRNRV 112 + +I GDGIGPE+ V A VP ++ +A E + ++++A RN Sbjct: 4 LAIIAGDGIGPEVTAEAVKVL-DAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD 62 Query: 113 ALKGNIETNHNLPPS--HKSRNNILRTSLDLYANVIHCKSLPGV---VTRHKDIDILIVR 167 A+ + ++P + LR LD + N+ + PGV ++ + ID ++VR Sbjct: 63 AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR 122 Query: 168 ENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKAN 223 E TEG Y+ G V + + T R+ AF+ A+ RK +T VHK N Sbjct: 123 EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKTN 181 Query: 224 IMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNV 283 ++ GL+L+ EV YP + VD T+ +++ P +FDV+V NL+G+I+ ++ Sbjct: 182 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 241 Query: 284 CAGLVGGPGLVAGANYGHVYA---VFETATRNTGKSIANKNIANPTATLLASCMMLDHLK 340 A + GG GL A N A +FE + IA + IA+PTA +++ ++L HL Sbjct: 242 AAAVCGGIGLAASGNIDATRANPSMFEP-VHGSAPDIAGQGIADPTAAIMSVALLLSHLG 300 Query: 341 LHSYATSIRKAV---LASMDNENMHTPDIG 367 H A + +AV LA+ +E + T D+G Sbjct: 301 EHDAAARVDRAVEAHLATRGSERLATSDVG 330 >1V5B-A nrPDB Length = 366 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 97/325 (29%), Positives = 169/325 (52%), Gaps = 31/325 (9%) Query: 54 RHTVTMIPGDGIGPELMLH----VKSVFRHACVPVDFEEVHVSSNADEED----IRNAIM 105 + + ++PGDGIGPE+M +K+V + FE + A +E + Sbjct: 2 KMKLAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETLD 61 Query: 106 AIRRNRVALKGNI---ETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVT---- 156 RR+ L G + + +HN P S + +L R + L+AN+ K+ ++ Sbjct: 62 ICRRSDAILLGAVGGPKWDHN-PASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPL 120 Query: 157 ---RHKDIDILIVRENTEGEYSSLEHESVA----GVVESLKIITKAKSLRIAEYAFKLAQ 209 R +++D++IVRE T G Y E VV++L T+ + RI E AF+LAQ Sbjct: 121 KRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTLAY-TREEIERIIEKAFQLAQ 179 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 RKK+ +V KAN+++ ++ + E A +YP + +M+VD+T MQL++ P QFDV Sbjct: 180 IR-RKKLASVDKANVLE-SSRMWREIAEETAKKYPDVELSHMLVDSTAMQLIANPGQFDV 237 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANY-GHVYAVFETATRNTGKSIANKNIANPTAT 328 +V N++G+I++++ + + G G++ A+ + ++E + IA + ANP T Sbjct: 238 IVTENMFGDILSDLASVITGSLGMLPSASLRSDRFGMYEP-VHGSAPDIAGQGKANPLGT 296 Query: 329 LLASCMMLDH-LKLHSYATSIRKAV 352 +L++ +ML + L A +I KAV Sbjct: 297 VLSAALMLRYSFGLEKEAAAIEKAV 321 >3VMJ-A nrPDB Length = 375 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 101/336 (30%), Positives = 165/336 (49%), Gaps = 40/336 (11%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFR----HACVPVDFEEVHVSSNADEEDIRN-------- 102 + + ++ GDGIGPE+M + V + + +++ E V A I N Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIA----IDNHGCPLPEA 69 Query: 103 AIMAIRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV-- 155 + L G++ LPP+ + L R +L+ N+ K G+ Sbjct: 70 TLKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHM 129 Query: 156 ------TRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKII-----TKAKSLRIAEYA 204 + D+L VRE T G Y + + G ES + ++ + RIA A Sbjct: 130 SPLRSDISARGFDVLCVRELTGGIYFG-KPKGRQGEGESEEAFDTMRYSRREISRIARIA 188 Query: 205 FKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRP 264 F+ A+ RKKVT+V KAN++ L+ Q EVA +P + E++ +DN TMQL+ RP Sbjct: 189 FEAAR-GRRKKVTSVDKANVLAC-SVLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRP 246 Query: 265 QQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHV-YAVFETATRNTGKSIANKNIA 323 +FDVM+ NL+G+I+++ A L G GL++ A+ + +FE A + IA K IA Sbjct: 247 DEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAG-GSAPDIAGKGIA 305 Query: 324 NPTATLLASCMMLDH-LKLHSYATSIRKAVLASMDN 358 NP A +L++ +ML H LK A++I +AV ++++ Sbjct: 306 NPIAQILSAALMLRHSLKQEEAASAIERAVTKALNS 341 >1VLC-A nrPDB Length = 366 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 103/337 (30%), Positives = 160/337 (47%), Gaps = 37/337 (10%) Query: 57 VTMIPGDGIGPELMLHVKSVFR--HACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRVAL 114 + ++PGDGIGPE++ V FE+V D D + ++ L Sbjct: 15 IAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGGDAIDRFGEPLPEETKKICL 74 Query: 115 KGNI--------ETNHNLPPSHKSRNN---ILRTSLDLYANV---------IHCKSLPGV 154 + + +LPP + LR L+LYAN+ +H L Sbjct: 75 EADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVYRSLVHVSPLKEK 134 Query: 155 VTRHKDIDILIVRENTEGEY----SSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQE 210 V +D++ VRE + G Y L+ E + I + RIA AF++A+ Sbjct: 135 VI-GSGVDLVTVRELSYGVYYGQPRGLDEEKGFDTM----IYDRKTVERIARTAFEIAKN 189 Query: 211 SGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVM 270 RKKVT+V KAN++ L+ + EVA YP + ++ VDN MQL+ +P QFDV+ Sbjct: 190 R-RKKVTSVDKANVL-YSSMLWRKVVNEVAREYPDVELTHIYVDNAAMQLILKPSQFDVI 247 Query: 271 VMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLL 330 + N++G+I+++ A L G GL+ A++G ++E A + IA KNIANP A +L Sbjct: 248 LTTNMFGDILSDESAALPGSLGLLPSASFGD-KNLYEPAG-GSAPDIAGKNIANPIAQIL 305 Query: 331 ASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI 366 + MML+H + A I +AV ++ E T DI Sbjct: 306 SLAMMLEHSFGMVEEARKIERAVELVIE-EGYRTRDI 341 >1CNZ-A nrPDB Length = 363 Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 105/357 (29%), Positives = 178/357 (49%), Gaps = 37/357 (10%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI----------RNAI 104 + + ++PGDGIGPE+M V V F+ +S+ D I + + Sbjct: 5 YHIAVLPGDGIGPEVMAQALKVMD--AVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATV 62 Query: 105 MAIRRNRVALKGNI--ETNHNLPP-SHKSRNNIL--RTSLDLYANVIHCK---SLPGVVT 156 + L G++ NLPP S R +L R L++N+ K L Sbjct: 63 EGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCP 122 Query: 157 RHKDI-----DILIVRENTEGEY-SSLEHESVAGVVE---SLKIITKAKSLRIAEYAFKL 207 DI DIL VRE T G Y + +G E ++ + + RIA AF+ Sbjct: 123 LRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFES 182 Query: 208 AQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQF 267 A++ R+KVT++ KAN+++ L+ + +VA YP + +M +DN TMQL+ P QF Sbjct: 183 ARKR-RRKVTSIDKANVLQ-SSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQF 240 Query: 268 DVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHV-YAVFETATRNTGKSIANKNIANPT 326 DV++ NL+G+I+++ CA + G G++ A+ + ++E A + IA KNIANP Sbjct: 241 DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAG-GSAPDIAGKNIANPI 299 Query: 327 ATLLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI--GGQGTTSEAIQDVI 380 A +L+ ++L + L + AT+I +A+ +++ E + T D+ G +++ + D+I Sbjct: 300 AQILSLALLLRYSLDANDAATAIEQAINRALE-EGVRTGDLARGAAAVSTDEMGDII 355 >3FMX-X nrPDB Length = 364 Score = 117 bits (292), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 104/363 (28%), Positives = 171/363 (47%), Gaps = 49/363 (13%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHACVP----VDFEEVHVSSNADEEDIRNAIM------A 106 + IPGDGIG E++ V A + ++F+ +S D +M Sbjct: 8 IAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWAS-CDYYLQHGKMMPDDWAEQ 66 Query: 107 IRRNRVALKGNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVT-----RHK 159 +++ G + +P ++L R D Y N+ + PGV + Sbjct: 67 LKQYDAIYFGAVGWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALANRKVG 126 Query: 160 DIDILIVRENTEGEYSSL--------EHESVAGVVESLKIITKAKSLRIAEYAFKLAQES 211 DID ++VRENTEGEYSSL E+E V + ES I T+ RI +YAF LA++ Sbjct: 127 DIDFVVVRENTEGEYSSLGGIMFENTENEIV--IQES--IFTRRGVDRILKYAFDLAEKR 182 Query: 212 GRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMV 271 RK VT+ K+N M + + + +AA YP ++++ +D + V +P++FDV+V Sbjct: 183 ERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFDVVV 242 Query: 272 MPNLYGNIVNNVCAGLVGGPGLVAGANYG---HVYAVFETATRNTGKSIANKNIANPTAT 328 NL+G+I++++ G G+ AN + ++FE + I KNIANP A Sbjct: 243 ASNLFGDILSDLGPACAGTIGIAPSANLNPERNFPSLFEP-VHGSAPDIFGKNIANPIAM 301 Query: 329 LLASCMMLDHL--------KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSE---AIQ 377 + + +ML+ L + H + + V+A + TPD+GG +T + AI Sbjct: 302 IWSGALMLEFLGQGDERYQRAHDDMLNAIERVIA----DGSVTPDMGGTLSTQQVGAAIS 357 Query: 378 DVI 380 D + Sbjct: 358 DTL 360 >5J32-A nrPDB Length = 403 Score = 116 bits (291), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 100/344 (29%), Positives = 169/344 (49%), Gaps = 30/344 (8%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEVHVSSNA-DEEDI---RNAIM 105 R+T+T++PGDGIGPE++ K+V + A V +F E+ + A D + I Sbjct: 40 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETIS 99 Query: 106 AIRRNRVALKGNI-----ETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRH-- 158 A + + L G I + N K I R +L ++AN+ LP +V Sbjct: 100 AAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQI-RAALKVFANLRPATVLPQLVDASTL 158 Query: 159 -----KDIDILIVRENTEGEYSS-----LEHESVAGVVESLKIITKAKSLRIAEYAFKLA 208 + +D+++VRE T G Y +E+ V + ++ + RIA AF+ A Sbjct: 159 KREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETA 218 Query: 209 QESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD 268 ++ R K+ +V KAN+++ L+ + +A+ YP + +M VDN MQLV P+QFD Sbjct: 219 RKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFD 276 Query: 269 VMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTAT 328 +V N++G+I+++ + + G G++ A+ + IA ++ ANP AT Sbjct: 277 TIVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLAT 336 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGT 371 +L++ M+L + L A I AVL +++N T DI GT Sbjct: 337 ILSAAMLLKYGLGEEKAAKRIEDAVLVALNN-GFRTGDIYSAGT 379 >1CM7-A nrPDB Length = 363 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 98/355 (27%), Positives = 174/355 (49%), Gaps = 33/355 (9%) Query: 55 HTVTMIPGDGIGPELMLH-------VKSVFRHACVPVDFEEVHVSSNADEEDIRNA-IMA 106 + + ++PGDGIGPE+M V++ F ++ + + + + A + Sbjct: 5 YHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEG 64 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCK---SLPGVVTRH 158 + L G++ +LPP + L R L++N+ K L Sbjct: 65 CEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 159 KDI-----DILIVRENTEGEY-SSLEHESVAGVVE---SLKIITKAKSLRIAEYAFKLAQ 209 DI DIL VRE T G Y + +G E ++ + + RIA AF+ A+ Sbjct: 125 ADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESAR 184 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 + R KVT++ KAN+++ L+ + E+A YP + +M +DN TMQL+ P QFDV Sbjct: 185 KR-RHKVTSIDKANVLQ-SSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDV 242 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHV-YAVFETATRNTGKSIANKNIANPTAT 328 ++ NL+G+I+++ CA + G G++ A+ + ++E A + IA KNIANP A Sbjct: 243 LLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAG-GSAPDIAGKNIANPIAQ 301 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI--GGQGTTSEAIQDVI 380 +L+ ++L + L A +I +A+ +++ E + T D+ G +++ + D+I Sbjct: 302 ILSLALLLRYSLDADDAACAIERAINRALE-EGIRTGDLARGAAAVSTDEMGDII 355 >2D4V-A nrPDB Length = 429 Score = 114 bits (286), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 107/374 (28%), Positives = 168/374 (44%), Gaps = 79/374 (21%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHACVPV-------DFEEVHVSSNA-----DEEDIRNAI 104 + I GDGIG ++ ++SV A V + E+ A + + + + Sbjct: 29 IPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQYLPDET 88 Query: 105 MA-IRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVT--RHKD- 160 MA IR +VA+KG +ET + +S N +R LDLY + + G + RH + Sbjct: 89 MAAIREYKVAIKGPLETP--VGGGIRSLNVAMRQDLDLYVCLRPVRYFEGTPSPMRHPEK 146 Query: 161 IDILIVRENTEGEYSSLEHESVAGVVESLKII---------TKAK--------------- 196 +D++I REN+E Y+ +E AG E+ KII TK + Sbjct: 147 VDMVIFRENSEDIYAGIEWP--AGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVSTE 204 Query: 197 -SLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC-----REVAARY------- 243 S R+ + A E G+ V+ VHK NIMK +G F RE A R Sbjct: 205 GSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGYALAEREFAGRVFTWRQKA 264 Query: 244 ---------------------PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNN 282 ++ +++I DN Q++ RP+ + V+ NL G+ V++ Sbjct: 265 AISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRPEDYSVVATLNLNGDYVSD 324 Query: 283 VCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLH 342 A VGG G+ GAN +A+FE AT T IA + ANP++ +L++ MML+HL Sbjct: 325 ALAAEVGGIGMAPGANLSDTHAIFE-ATHGTAPDIAGQGKANPSSLILSAVMMLEHLGWG 383 Query: 343 SYATSIRKAVLASM 356 A +I A+ A++ Sbjct: 384 EAAQAIVAAMNATI 397 >1HQS-A nrPDB Length = 423 Score = 114 bits (285), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 101/368 (27%), Positives = 159/368 (43%), Gaps = 75/368 (20%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNA----DEEDIRNAIM 105 + I GDG GP++ V A + ++EV+ A E + Sbjct: 22 IPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAETLD 81 Query: 106 AIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYA---NVIHCKSLPGVVTRHKDID 162 IR +A+KG + T + +S N LR LDL+ V + +P V R +D D Sbjct: 82 VIREYFIAIKGPLTTP--VGGGIRSLNVALRQELDLFVCLRPVRYFTGVPSPVKRPEDTD 139 Query: 163 ILIVRENTEGEYSSLEHESVAGVVESL-----------------------KIITKAKSLR 199 ++I RENTE Y+ +E+ + V+ L K +++ + R Sbjct: 140 MVIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKIRFPETSGIGIKPVSEEGTSR 199 Query: 200 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA-----------ARYPQITF 248 + A A E GRK VT VHK NIMK +G F E+A A+Y +I Sbjct: 200 LVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAEKEYGDKVFTWAQYDRIAE 259 Query: 249 E----------------------NMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAG 286 E + I D Q+++RP +FDV+ NL G+ +++ A Sbjct: 260 EQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEFDVVATMNLNGDYISDALAA 319 Query: 287 LVGGPGLVAGA--NYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSY 344 VGG G+ GA NY +A+FE AT T A + NP++ +L+ ++L+HL + Sbjct: 320 QVGGIGIAPGANINYETGHAIFE-ATHGTAPKYAGLDKVNPSSVILSGVLLLEHLGWNEA 378 Query: 345 ATSIRKAV 352 A + K++ Sbjct: 379 ADLVIKSM 386 >5M2E-A nrPDB Length = 418 Score = 107 bits (267), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 100/356 (28%), Positives = 158/356 (44%), Gaps = 66/356 (18%) Query: 57 VTMIPGDGIG----PELMLHVKSVFRHACV---PVDFEEVHVSSNA----DEEDI--RNA 103 + I GDGIG P ++ V + A + + EV+ A D++ + Sbjct: 31 IPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQET 90 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYA---NVIHCKSLPGVVTRHKD 160 + A+R V++KG + T + +S N LR LDLY V + +P V + D Sbjct: 91 LDAVRDYVVSIKGPLTTP--VGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVKKPGD 148 Query: 161 IDILIVRENTEGEYSSLEHESVAGVVESLKII-------------------------TKA 195 +D++I REN+E Y+ +E + AG E+ K+I ++ Sbjct: 149 VDMVIFRENSEDIYAGVEWK--AGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQE 206 Query: 196 KSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY---------PQI 246 + R+ A + A ++ R VT VHK NIMK +G F EVA P + Sbjct: 207 GTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELLDGGPWM 266 Query: 247 TFEN-----------MIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVA 295 F+N +I D Q++ RP ++DV+ NL G+ +++ A VGG G+ Sbjct: 267 QFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATLNLNGDYLSDALAAEVGGIGIAP 326 Query: 296 GANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKA 351 GAN A+FE AT T A ++ NP + +L++ MML H+ A I K Sbjct: 327 GANLSDSVAMFE-ATHGTAPKYAGQDKVNPGSLILSAEMMLRHMGWTEAADLIIKG 381 >6C0E-A nrPDB Length = 419 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 101/391 (25%), Positives = 177/391 (45%), Gaps = 67/391 (17%) Query: 57 VTMIPGDGIG----PELMLHVKSVFRHAC---VPVDFEEVHVSSNA------DEEDIRNA 103 + I GDGIG P ++ V + + A + + EV+ A D+ + Sbjct: 32 IPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKET 91 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYA---NVIHCKSLPGVVTRHKD 160 + A+++ V++KG + T + +S N +R +DLY + + +P V Sbjct: 92 LDAMKKYVVSIKGPLTTP--VGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWK 149 Query: 161 IDILIVRENTEGEYSSLEHES----VAGVVESL-------------------KIITKAKS 197 D++I REN+E Y+ +E ++ V++ L K +++ + Sbjct: 150 TDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGT 209 Query: 198 LRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA------ARY---PQITF 248 R+ + A + A ++ R VT VHK NIMK +G F +VA Y P + F Sbjct: 210 TRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEF 269 Query: 249 EN-----------MIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGA 297 +N +I D Q++ RP+ + V+ NL G+ +++ A VGG G+ GA Sbjct: 270 KNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAPGA 329 Query: 298 NYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMD 357 N AVFE AT T A +N NP + +L++ MML H+ + A I + + +++ Sbjct: 330 NISDQMAVFE-ATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIE 388 Query: 358 NENM-HTPDIGGQGTT---SEAIQD-VIRHI 383 + + + + G QG T S D +I+H+ Sbjct: 389 AKTVTYDFERGMQGATLVSSSGFADAMIKHM 419 >1AI3-A nrPDB Length = 416 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 98/360 (27%), Positives = 162/360 (45%), Gaps = 62/360 (17%) Query: 57 VTMIPGDGIG----PELMLHVKSVFRHACV---PVDFEEVHVSSNADE---EDIR---NA 103 + I GDGIG P ++ V + A + + E++ + + +D+ Sbjct: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYA---NVIHCKSLPGVVTRHKD 160 + IR RVA+KG + T + +S N LR LDLY V + + P V + Sbjct: 89 LDLIREYRVAIKGPLTTP--VGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPEL 146 Query: 161 IDILIVRENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEY------------- 203 D++I REN+E Y+ +E ++ + V++ L+ K +R E+ Sbjct: 147 TDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGT 206 Query: 204 ------AFKLAQESGRKKVTAVHKANIMKLGDGLF----LQCCRE------------VAA 241 A + A + R VT VHK NIMK +G F Q RE + Sbjct: 207 KRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKV 266 Query: 242 RYP----QITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGA 297 + P +I +++I D Q++ RP ++DV+ NL G+ +++ A VGG G+ GA Sbjct: 267 KNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGA 326 Query: 298 NYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMD 357 N G A+FE AT T A ++ NP + +L++ MML H+ A I K + +++ Sbjct: 327 NIGDECALFE-ATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAIN 385 >3DMS-A nrPDB Length = 427 Score = 103 bits (257), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 126/279 (45%), Gaps = 47/279 (16%) Query: 129 KSRNNILRTSLDLYA---NVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEH----ES 181 +S N LR LDLY + + K +P V + +++I REN+E Y+ +E E Sbjct: 122 RSLNVALRQELDLYVCLRPIQYFKGVPSPVREPEKTNMVIFRENSEDIYAGIEWAAESEQ 181 Query: 182 VAGVVESL-------------------KIITKAKSLRIAEYAFKLAQESGRKKVTAVHKA 222 V++ L K ++K + R+ A + A ++ RK VT VHK Sbjct: 182 AKKVIKFLQEEMGVKKIRFPQTSGIGIKPVSKEGTERLVRKAIQYAIDNDRKSVTLVHKG 241 Query: 223 NIMKLGDGLFLQCCREVAARY---------PQITFEN-----------MIVDNTTMQLVS 262 NIMK +G F +A + P + F+N I D Q++ Sbjct: 242 NIMKFTEGAFRDAGYALAQKEFGAELIDGGPWMKFKNPKTGNEIVVKDSIADAFLQQILL 301 Query: 263 RPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNI 322 RP ++DV+ NL G+ +++ A VGG G+ GAN A+FE AT T A K+ Sbjct: 302 RPAEYDVIATLNLNGDYISDALAAQVGGIGIAPGANLSDSVAMFE-ATHGTAPKYAGKDY 360 Query: 323 ANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENM 361 NP + +L++ MML HL A I A+ S+ + + Sbjct: 361 VNPGSEILSAEMMLRHLGWTEAADVIISAMEKSIKQKRV 399 >4IWH-A nrPDB Length = 363 Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 92/340 (27%), Positives = 155/340 (45%), Gaps = 30/340 (8%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED---IRNAIMAIRRNRVA 113 + ++PGDGIGPE++ V + E V E + +A +A+ + A Sbjct: 11 IAVLPGDGIGPEIVNEAVKVLNALDEKFELEHAPVGGAGYEASGHPLPDATLALAKEADA 70 Query: 114 LK----GNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRH-------KD 160 + G+ + + +L + + IL R L+L+AN P +V Sbjct: 71 ILFGAVGDWKYD-SLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVAG 129 Query: 161 IDILIVRENTEGEY-------SSLEHESVAGVVESLKII--TKAKSLRIAEYAFKLAQES 211 +DILIVRE Y + AG E + ++ + RIA AF+ AQ+ Sbjct: 130 LDILIVRELNGDIYFGQPRGVRAAPDGPFAGEREGFDTMRYSEPEVRRIAHVAFQAAQKR 189 Query: 212 GRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMV 271 KK+ +V K+N+++ + +V+ Y + +M VDN MQL P+QFDV+V Sbjct: 190 A-KKLLSVDKSNVLETSQ-FWRDVMIDVSKEYADVELSHMYVDNAAMQLAKAPKQFDVIV 247 Query: 272 MPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLA 331 N++G+I+++ + L G G++ A+ + + IA K IANP AT+L+ Sbjct: 248 TGNMFGDILSDEASMLTGSIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGIANPLATILS 307 Query: 332 SCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQG 370 + M+L + L A I +AV ++ + T DI G Sbjct: 308 AAMLLRYSLNRAEQADRIERAVKTVLE-QGYRTGDIATPG 346 >3UDO-A nrPDB Length = 361 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 98/358 (27%), Positives = 159/358 (44%), Gaps = 39/358 (10%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNA----------- 103 + V ++ GDGIGP +M + +F S +E I A Sbjct: 7 YKVAVLAGDGIGPLVMKEALKILTFIAQKYNF-----SFELNEAKIGGASIDAYGVALSD 61 Query: 104 --IMAIRRNRVALKGNI--ETNHNLPPSHK-SRNNIL--RTSLDLYANVIHCKSLPGVV- 155 + ++ L G++ NLP + R ++L R +L+AN+ CK + Sbjct: 62 ETLKLCEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTH 121 Query: 156 -------TRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLA 208 K +DIL VRE T G Y + ++ +I TK + RIA AF+ A Sbjct: 122 ASPLKNEIIQKGVDILCVRELTGGIYFGKQDLGKESAYDT-EIYTKKEIERIARIAFESA 180 Query: 209 QESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD 268 + +KKV + KAN++ L+ + VA Y I E M VDN MQ+V P FD Sbjct: 181 RIR-KKKVHLIDKANVLA-SSILWREVVANVAKDYQDINLEYMYVDNAAMQIVKNPSIFD 238 Query: 269 VMVMPNLYGNIVNNVCAGL-VGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTA 327 VM+ NL+G+I+++ A + L + + + ++E A + IA+ NIANP A Sbjct: 239 VMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAG-GSAPDIAHLNIANPIA 297 Query: 328 TLLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQG-TTSEAIQDVIRHI 383 +L++ +ML + K A I A+ ++ M T D+ + ++ + D I I Sbjct: 298 QILSAALMLKYSFKEEQAAQDIENAISLALAQGKM-TKDLNAKSYLNTDEMGDCILEI 354 >2C07-A nrPDB Length = 285 Score = 33.5 bits (75), Expect = 0.17, Method: Compositional matrix adjust. Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 17/138 (12%) Query: 229 DGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLV 288 D LFL R +E+++ N L Q ++ N YG I+N + +V Sbjct: 134 DNLFL--------RMKNDEWEDVLRTNLN-SLFYITQPISKRMINNRYGRIIN--ISSIV 182 Query: 289 GGPGLVAGANYGHVYAVFETATRNTGKSIANKNIA-NPTATLLASCMMLDHLKLHSYATS 347 G G V ANY A T++ K +A++NI N A S M D + + Sbjct: 183 GLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPGFISSDMTDKI-----SEQ 237 Query: 348 IRKAVLASMDNENMHTPD 365 I+K +++++ M TP+ Sbjct: 238 IKKNIISNIPAGRMGTPE 255 >1UPX-A nrPDB Length = 544 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 11/105 (10%) Query: 118 IETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSL 177 + TN +PP ++ + T + CK +PG + HKD +I T + + Sbjct: 304 LTTNCLVPPKDSYKDRVYTTGI---VGFTGCKHIPGEIGEHKDFSAIIAHAKTCPAPTEI 360 Query: 178 EHESVAG-------VVESLKIITKAKSLRIAEYAFKLAQESGRKK 215 E + G + + K+I KS I ++ +A GR K Sbjct: 361 ESGEIIGGFAHNQVLALADKVIDAVKSGAIKKFVV-MAGCDGRAK 404 >4ZP1-A nrPDB Length = 568 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 18/93 (19%) Query: 216 VTAVHKANIMKLGDGLFLQCCREVAA----RYPQITFENMIVDNTTMQLVSRPQQFDVMV 271 V A + NI+ +GDG F +EVA + P I F +++N + VM+ Sbjct: 427 VGAPERRNILMVGDGSFQLTAQEVAQMVRLKLPVIIF---LINNYGYTIA-------VMI 476 Query: 272 MPNLYGNIVNNVCAGLV----GGPGLVAGANYG 300 Y NI N AGL+ G G +GA G Sbjct: 477 HDGPYNNIKNWDYAGLMEVFNGNGGYDSGAGKG 509 >4KPO-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 13/46 (28%), Positives = 24/46 (52%) Query: 153 GVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSL 198 G+ H +D+L+ + N+E ++ SVA V+ K++ K L Sbjct: 281 GICVGHTSMDMLLKKWNSENPWTGYSPISVAWTVDVPKVVAFVKEL 326 >3PMN-A nrPDB Length = 329 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 151 LPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLA 208 LPG RH+ +DI++V +E + L A S++ + K K + ++E+A A Sbjct: 233 LPGPGRRHRRLDIIVV-PYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTA 289 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5GRH-B nrPDB 496 e-141 5YVT-A nrPDB 440 e-124 3BLX-A nrPDB 435 e-122 2D1C-A nrPDB 410 e-115 3BLV-B nrPDB 409 e-114 3ASJ-A nrPDB 397 e-111 1CM7-A nrPDB 374 e-104 3U1H-A nrPDB 373 e-104 2IV0-A nrPDB 373 e-104 1CNZ-A nrPDB 371 e-103 1XAD-A nrPDB 371 e-103 1WPW-A nrPDB 370 e-103 4Y1P-A nrPDB 370 e-103 1IDM-A nrPDB 370 e-103 1AI3-A nrPDB 360 e-100 3VMJ-A nrPDB 359 e-100 3VML-A nrPDB 359 1e-99 2E5M-A nrPDB 358 2e-99 6C0E-A nrPDB 358 2e-99 5M2E-A nrPDB 358 2e-99 1VLC-A nrPDB 357 4e-99 3VMK-A nrPDB 356 7e-99 3TY3-A nrPDB 354 4e-98 1HQS-A nrPDB 351 2e-97 2D4V-A nrPDB 351 3e-97 3DMS-A nrPDB 351 4e-97 5J32-A nrPDB 350 6e-97 1V5B-A nrPDB 348 2e-96 5HN5-A nrPDB 345 2e-95 1A05-A nrPDB 341 3e-94 4IWH-A nrPDB 340 5e-94 3FMX-X nrPDB 338 2e-93 1XGV-A nrPDB 337 4e-93 3UDO-A nrPDB 335 2e-92 2G4O-A nrPDB 306 1e-83 Sequences not found previously or not previously below threshold: 1ZOR-A nrPDB 82 5e-16 2QFY-A nrPDB 81 9e-16 5I96-A nrPDB 73 2e-13 6BL1-B nrPDB 68 6e-12 4AOY-A nrPDB 67 2e-11 3US8-A nrPDB 63 2e-10 4HCX-A nrPDB 63 2e-10 2UXQ-A nrPDB 52 5e-07 4A8J-A nrPDB 35 0.049 5Z16-A nrPDB 35 0.068 4JQP-A nrPDB 34 0.098 1J1W-A nrPDB 33 0.25 2C07-A nrPDB 31 0.81 6G3U-A nrPDB 30 1.7 4ZDA-A nrPDB 30 1.7 4U33-A nrPDB 30 1.9 4ATY-A nrPDB 30 1.9 5VAW-A nrPDB 30 2.1 5KVU-A nrPDB 30 2.5 5CFV-A nrPDB 30 2.5 1YE8-A nrPDB 30 2.6 1D5A-A nrPDB 30 2.7 2B0T-A nrPDB 30 2.7 3ZYY-X nrPDB 30 2.9 1F1E-A nrPDB 29 3.0 2XIG-A nrPDB 29 3.4 3RUY-A nrPDB 29 4.4 1CHM-A nrPDB 29 4.5 5T05-A nrPDB 28 5.2 5HZV-A nrPDB 28 5.2 4WRN-A nrPDB 28 5.2 3PY7-A nrPDB 28 5.2 2VWK-A nrPDB 28 5.2 5W0U-B nrPDB 28 5.3 3OB4-A nrPDB 28 5.4 6EG3-A nrPDB 28 5.8 5BT8-A nrPDB 28 5.9 6MUU-A nrPDB 28 6.2 3DM0-A nrPDB 28 6.4 5HZW-A nrPDB 28 6.5 5II5-A nrPDB 28 6.8 4K8X-A nrPDB 28 7.0 5IIC-A nrPDB 28 7.1 1MZB-A nrPDB 28 7.7 5HZ7-A nrPDB 28 8.1 4IFP-A nrPDB 28 8.2 6D67-A nrPDB 28 8.4 4XZS-A nrPDB 28 8.4 5Y2G-A nrPDB 28 8.5 5JST-A nrPDB 28 8.7 6DD2-A nrPDB 28 8.8 5WQ6-A nrPDB 28 8.8 1O5O-A nrPDB 28 9.5 5GPQ-A nrPDB 28 9.5 4XA2-A nrPDB 28 9.5 3VD8-A nrPDB 28 9.7 5TJ4-A nrPDB 28 9.9 >5GRH-B nrPDB Length = 354 Score = 496 bits (1278), Expect = e-141, Method: Composition-based stats. Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 40 FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED 99 FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED Sbjct: 1 FSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED 60 Query: 100 IRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHK 159 IRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHK Sbjct: 61 IRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHK 120 Query: 160 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV 219 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV Sbjct: 121 DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAV 180 Query: 220 HKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI 279 HKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI Sbjct: 181 HKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI 240 Query: 280 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL 339 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL Sbjct: 241 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL 300 Query: 340 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA 393 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA Sbjct: 301 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVINGRAVEA 354 >5YVT-A nrPDB Length = 339 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 149/341 (43%), Positives = 214/341 (62%), Gaps = 8/341 (2%) Query: 52 GGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHV----SSNADEEDIRNAIMAI 107 GG TVT+IPGDGIGPE+ V +F A P+ +EE +V A ++ Sbjct: 2 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 61 Query: 108 RRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVR 167 +N++ LKG ++T + H S N +LR + DLYANV C S+ G T + D++I+ +R Sbjct: 62 DKNKMGLKGPLKTP--IAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIR 119 Query: 168 ENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKL 227 ENTEGEYS +EH V GVV+S+K+IT+ S RIAE+AF+ A+ + R VTAVHKANIM++ Sbjct: 120 ENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRM 179 Query: 228 GDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGL 287 DGLFLQ CREVA I F M +D + +V P QFDV+VMPNLYG+I++++CAGL Sbjct: 180 SDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGL 239 Query: 288 VGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYAT 346 +GG G+ N G + A+FE + T IA K++ANPTA LL++ MML H+ L +A Sbjct: 240 IGGLGVTPSGNIGANGVAIFE-SVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAA 298 Query: 347 SIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVIN 387 I A A++ + T D+GG S+ +++ R ++ ++ Sbjct: 299 RIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD 339 >3BLX-A nrPDB Length = 349 Score = 435 bits (1118), Expect = e-122, Method: Composition-based stats. Identities = 170/347 (48%), Positives = 238/347 (68%), Gaps = 4/347 (1%) Query: 41 SEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDI 100 +E+T+P KYGGR TVT+IPGDG+G E+ V+++F +P+D+E +++ +E + Sbjct: 6 AERTLP--KKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGV 63 Query: 101 RNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKD 160 A+ +++RN++ LKG T + H S N LR LD+YANV KSL GV TR D Sbjct: 64 YEAVESLKRNKIGLKGLWHTPAD-QTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPD 122 Query: 161 IDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVH 220 ID++++RENTEGE+S LEHESV GVVESLK++T+ K+ RIA +AF A++ RK VTAVH Sbjct: 123 IDLIVIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVH 182 Query: 221 KANIMKLGDGLFLQCCREVA-ARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNI 279 KANIMKLGDGLF E+ YP I ++IVDN +MQ V++P QFDV+V P++YG I Sbjct: 183 KANIMKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTI 242 Query: 280 VNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL 339 + N+ A L+GGPGLVAGAN+G YAVFE +R+ G I +N+ANPTA +L+S +ML+HL Sbjct: 243 LGNIGAALIGGPGLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHL 302 Query: 340 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 386 L+ YAT I KAV ++ T DIGG +T++ ++I + + Sbjct: 303 GLNEYATRISKAVHETIAEGKHTTRDIGGSSSTTDFTNEIINKLSTM 349 >2D1C-A nrPDB Length = 496 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 126/341 (36%), Positives = 193/341 (56%), Gaps = 13/341 (3%) Query: 53 GRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEED-----IRNAIMAI 107 GR +T+IPGDGIGPE + V A P+ +E ++ + I +I Sbjct: 18 GRKLITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESI 77 Query: 108 RRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRH--KDIDILI 165 R+ RV LKG +ET + KS N LR + YANV + P V T + + ID+++ Sbjct: 78 RKTRVVLKGPLETP--VGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAGRGIDLVV 135 Query: 166 VRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIM 225 VREN E Y+ +EH V ++LK+I+ S +I +AF+LA+ GRKKV K+NIM Sbjct: 136 VRENVEDLYAGIEHMQTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIM 195 Query: 226 KLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCA 285 KL +G + +VA YP I ++IVDN QLV RP+QF+V+V N+ G+I++++ + Sbjct: 196 KLAEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTS 255 Query: 286 GLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYA 345 GL+GG G AN G+ A+FE A + A KN+ NPTA LL++ MML +L+ + A Sbjct: 256 GLIGGLGFAPSANIGNEVAIFE-AVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEFATA 314 Query: 346 TSIRKAVLASMDNENMHTPDIGGQ---GTTSEAIQDVIRHI 383 I A+L +++ + T D+ G T+E + +I+++ Sbjct: 315 DLIENALLYTLEEGRVLTGDVVGYDRGAKTTEYTEAIIQNL 355 >3BLV-B nrPDB Length = 354 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 137/338 (40%), Positives = 211/338 (62%), Gaps = 10/338 (2%) Query: 53 GRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS---NADEEDIRNAIMAIRR 109 G++TV+ I GDGIGPE+ VK +F A VP+++E VS N A+ +I + Sbjct: 20 GKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITK 79 Query: 110 NRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVREN 169 N VALKG + T + H+S N LR + L+ANV KS+ G T ++++D++++REN Sbjct: 80 NLVALKGPLATP--IGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIREN 137 Query: 170 TEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGD 229 TEGEYS +EH GVV+S+K+IT+ S R+ YAF+ A+ GR +V VHK+ I +L D Sbjct: 138 TEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLAD 197 Query: 230 GLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD--VMVMPNLYGNIVNNVCAGL 287 GLF+ +E++ YP +T E ++DN+ +++V+ P + V V PNLYG+I++++ +GL Sbjct: 198 GLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGL 257 Query: 288 -VGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYAT 346 G GL AN GH ++FE A + IA ++ ANPTA LL+S MML+H+ L ++A Sbjct: 258 SAGSLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHAD 316 Query: 347 SIRKAVLASMDNE-NMHTPDIGGQGTTSEAIQDVIRHI 383 I+ AVL+++ + T D+ G TTS + VI+ + Sbjct: 317 QIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 354 >3ASJ-A nrPDB Length = 334 Score = 397 bits (1021), Expect = e-111, Method: Composition-based stats. Identities = 122/336 (36%), Positives = 173/336 (51%), Gaps = 8/336 (2%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEE----DIRNAIMAIRRN 110 + + +I GDGIG E++ + V +P++F E E + I Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSC 62 Query: 111 RVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENT 170 L G + P LR LDLYANV KS P V +D++IVRENT Sbjct: 63 HATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRP-VPGSRPGVDLVIVRENT 121 Query: 171 EGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDG 230 EG Y E + V + +I+K S RI A ++A+ RK + HKAN++ L G Sbjct: 122 EGLYVEQERRYLD-VAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQG 180 Query: 231 LFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGG 290 LFL +EVA +P + +++IVDN MQLV RP++FDV+V NL G+I++++ AGLVGG Sbjct: 181 LFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDILSDLAAGLVGG 240 Query: 291 PGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRK 350 GL N G AVFE + IA K IANPTA +L++ MMLD+L A + K Sbjct: 241 LGLAPSGNIGDTTAVFEP-VHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRVEK 299 Query: 351 AVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 386 AV + TPD+GG TT + V+ ++ + Sbjct: 300 AVDLVL-ERGPRTPDLGGDATTEAFTEAVVEALKSL 334 >1CM7-A nrPDB Length = 363 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 96/357 (26%), Positives = 166/357 (46%), Gaps = 33/357 (9%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRH----ACVPVDFEEVHVSSNA----DEEDIRNAIMA 106 + + ++PGDGIGPE+M V + + V A + + Sbjct: 5 YHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEG 64 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV------ 155 + L G++ +LPP + L R L++N+ K G+ Sbjct: 65 CEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 156 --TRHKDIDILIVRENTEGEYSSLE-HESVAGVVE---SLKIITKAKSLRIAEYAFKLAQ 209 DIL VRE T G Y +G E ++ + + RIA AF+ A+ Sbjct: 125 ADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESAR 184 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 + R KVT++ KAN+++ L+ + E+A YP + +M +DN TMQL+ P QFDV Sbjct: 185 KR-RHKVTSIDKANVLQ-SSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDV 242 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYGH-VYAVFETATRNTGKSIANKNIANPTAT 328 ++ NL+G+I+++ CA + G G++ A+ + ++E A + IA KNIANP A Sbjct: 243 LLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAG-GSAPDIAGKNIANPIAQ 301 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI--GGQGTTSEAIQDVIRH 382 +L+ ++L + L A +I +A+ ++ E + T D+ G +++ + D+I Sbjct: 302 ILSLALLLRYSLDADDAACAIERAINRAL-EEGIRTGDLARGAAAVSTDEMGDIIAR 357 >3U1H-A nrPDB Length = 390 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 103/355 (29%), Positives = 166/355 (46%), Gaps = 31/355 (8%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNADEE----DIRNAIM 105 + + ++PGDGIGPE+M V +FE + A +E + Sbjct: 23 KKKIAVLPGDGIGPEVMEAAIEVLKAVAERFGHEFEFEYGLIGGAAIDEAGTPLPEETLD 82 Query: 106 AIRRNRVALKGNI--ETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRHK-- 159 R + L G + P + +L R LDL+AN+ K + Sbjct: 83 VCRGSDAILLGAVGGPKWDQNPSELRPEKGLLGIRKGLDLFANLRPVKVYDSLADASPLK 142 Query: 160 -----DIDILIVRENTEGEYSSLE---HESVAGVVESLKIITKAKSLRIAEYAFKLAQES 211 +D++IVRE T G Y +E + T+ + RI AF+LA Sbjct: 143 KEVIEGVDLVIVRELTGGLYFGEPSERYEEGEEAAVDTLLYTREEIERIIRKAFELALTR 202 Query: 212 GRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMV 271 +KKVT+V KAN+++ L+ + EVA YP + E+M+VDN MQL+ P+QFDV+V Sbjct: 203 -KKKVTSVDKANVLE-SSRLWREVAEEVAKEYPDVELEHMLVDNAAMQLIRNPRQFDVIV 260 Query: 272 MPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTATLL 330 N++G+I+++ + + G G++ A+ ++E + IA K IANP AT+L Sbjct: 261 TENMFGDILSDEASMITGSLGMLPSASLSTDGLGLYEP-VHGSAPDIAGKGIANPLATIL 319 Query: 331 ASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI---GGQGTTSEAIQDVIR 381 ++ MML + L A +I KAV + E T DI GG+ ++ + D ++ Sbjct: 320 SAAMMLRYSFGLEEEAKAIEKAVEKVLA-EGYRTADIAKPGGKYVSTTEMTDEVK 373 >2IV0-A nrPDB Length = 412 Score = 373 bits (958), Expect = e-104, Method: Composition-based stats. Identities = 102/389 (26%), Positives = 174/389 (44%), Gaps = 61/389 (15%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVD----FEEVHVSSNA----DEEDIRNAIMA 106 + GDGIG +++ V A + + +V+ +A + + A Sbjct: 28 PIIPYFEGDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNYLPDDTLNA 87 Query: 107 IRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHC---KSLPGVVTRHKDIDI 163 I+ RVALKG + T + ++S N +R LDLYANV K +P + + ++ Sbjct: 88 IKEFRVALKGPLTTP--VGGGYRSLNVTIRQVLDLYANVRPVYYLKGVPSPIKHPEKVNF 145 Query: 164 LIVRENTEGEYSSLEHESVAGVV--------------------ESLKIITKAKSLRIAEY 203 +I RENTE Y+ +E + +K I++ + R+ Sbjct: 146 VIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEFGVTIREDSGIGIKPISEFATKRLVRM 205 Query: 204 AFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY-------------------- 243 A + A E+ RK VT VHK NIMK +G F EVA + Sbjct: 206 AIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQEFGEYCITEDELWDKYGGKQP 265 Query: 244 -PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHV 302 +I ++ I DN Q+++R ++DV+ +PNL G+ +++ A L+GG G+ G+N G Sbjct: 266 EGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGDYLSDAAAALIGGLGIAPGSNIGDG 325 Query: 303 YAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMH 362 VFE + A +N NPTA +L +M +++ + I+KAV ++ + + Sbjct: 326 IGVFEP-VHGSAPKYAGQNKVNPTAEILTGALMFEYIGWKDASEMIKKAVEMTISS-GIV 383 Query: 363 TPDI-----GGQGTTSEAIQDVIRHIRVI 386 T DI G + T E + V+ +++ + Sbjct: 384 TYDIHRHMGGTKVGTREFAEAVVENLQSL 412 >1CNZ-A nrPDB Length = 363 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 97/357 (27%), Positives = 170/357 (47%), Gaps = 33/357 (9%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVD-------FEEVHVSSNADEEDIRN-AIMA 106 + + ++PGDGIGPE+M V D ++ ++ + + + Sbjct: 5 YHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEG 64 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV------ 155 + L G++ NLPP + L R L++N+ K G+ Sbjct: 65 CEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 156 --TRHKDIDILIVRENTEGEYSSLE-HESVAGVVE---SLKIITKAKSLRIAEYAFKLAQ 209 DIL VRE T G Y +G E ++ + + RIA AF+ A+ Sbjct: 125 ADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESAR 184 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 + RK VT++ KAN+++ L+ + +VA YP + +M +DN TMQL+ P QFDV Sbjct: 185 KRRRK-VTSIDKANVLQ-SSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQFDV 242 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYGH-VYAVFETATRNTGKSIANKNIANPTAT 328 ++ NL+G+I+++ CA + G G++ A+ + ++E A + IA KNIANP A Sbjct: 243 LLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAG-GSAPDIAGKNIANPIAQ 301 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI--GGQGTTSEAIQDVIRH 382 +L+ ++L + L + AT+I +A+ ++ E + T D+ G +++ + D+I Sbjct: 302 ILSLALLLRYSLDANDAATAIEQAINRAL-EEGVRTGDLARGAAAVSTDEMGDIIAR 357 >1XAD-A nrPDB Length = 345 Score = 371 bits (953), Expect = e-103, Method: Composition-based stats. Identities = 99/349 (28%), Positives = 157/349 (44%), Gaps = 25/349 (7%) Query: 55 HTVTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNA----DEEDIRNAIMA 106 V ++PGDGIGPE+ V + + +E A E Sbjct: 1 MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKG 60 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRHK--- 159 + L G++ P + +L R LDL+AN+ K + Sbjct: 61 VEEAEAVLLGSVGGPKWDQNPRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASPLKK 120 Query: 160 ----DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKK 215 ++D +IVRE T G Y + + +K + R+A AF+ A++ RK Sbjct: 121 EYIDNVDFVIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKH 179 Query: 216 VTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNL 275 V +V KAN++++G+ + + EV YP + E+ VD M LV P +FDV+V N+ Sbjct: 180 VVSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNI 238 Query: 276 YGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMM 335 +G+I++++ + L G GL+ A+ G VFE + IA K IANPTA +L++ MM Sbjct: 239 FGDILSDLASVLPGSLGLLPSASLGRGTPVFEP-VHGSAPDIAGKGIANPTAAILSAAMM 297 Query: 336 LDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 L+H L A + AV ++ PD+GG T V+RH+ Sbjct: 298 LEHAFGLVELARKVEDAVAKALLE--TPPPDLGGSAGTEAFTATVLRHL 344 >1WPW-A nrPDB Length = 336 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 119/344 (34%), Positives = 175/344 (50%), Gaps = 25/344 (7%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEVHVSSNA----DEEDIRNAIMA 106 TV +I GDGIGPE++ K + +P+++ EV A E ++++ Sbjct: 2 FTVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKI 61 Query: 107 IRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIV 166 I + + LKG + S LR D+YAN+ KS+PG+ T++ ++DILIV Sbjct: 62 IDKADIILKGP------VGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGNVDILIV 115 Query: 167 RENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMK 226 RENTE Y EH GV +KIIT+ S RIA+ A RKKVT VHKAN+M+ Sbjct: 116 RENTEDLYKGFEHIVSDGVAVGMKIITRFASERIAKVGLNFALRR-RKKVTCVHKANVMR 174 Query: 227 LGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAG 286 + DGLF + CR V ++ + M VD LV PQ FDV+V N+YG+I+++ + Sbjct: 175 ITDGLFAEACRSVLK--GKVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQ 232 Query: 287 LVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL------- 339 + G G+ AN G A+FE IA KNI NPTA LL+ MM + + Sbjct: 233 IAGSLGIAPSANIGDKKALFEP-VHGAAFDIAGKNIGNPTAFLLSVSMMYERMYELSNDD 291 Query: 340 KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 + + ++ A+ TPD+GG TT + I ++ + Sbjct: 292 RYIKASRALENAIYLVYKERKALTPDVGGNATTDDLINEIYNKL 335 >4Y1P-A nrPDB Length = 337 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 124/345 (35%), Positives = 180/345 (52%), Gaps = 27/345 (7%) Query: 55 HTVTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNA----DEEDIRNAIMA 106 V +I GDGIGPE++ K++ +P+++ EV + ++++ Sbjct: 3 FVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRV 62 Query: 107 IRRNRVALKGNI-ETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILI 165 I + + LKG + ET ++ LR DLYAN+ KSLPG+ + D+DIL+ Sbjct: 63 IEKADMILKGPVGETAADVV-------VKLRLMYDLYANLRPAKSLPGLENKFGDVDILV 115 Query: 166 VRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIM 225 VRENTE Y LEH GV +K+IT+A S RIA+ A A +KKV VHK+N+M Sbjct: 116 VRENTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALRR-KKKVVCVHKSNVM 174 Query: 226 KLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCA 285 ++ DGLF + CR V ++ + M VD LV PQ FDV+V N YG+I+++ Sbjct: 175 RITDGLFAESCRNVLK--GKVEYSEMYVDAAAANLVRNPQAFDVIVTENTYGDILSDEAG 232 Query: 286 GLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHL------ 339 + G G+ AN G ++FE IA KNIANPTA LL+ MMLD + Sbjct: 233 QIAGSLGISPSANIGDRKSLFEP-VHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGD 291 Query: 340 -KLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 + ++ A S+R A+ + TPD+GG TT E I + I Sbjct: 292 IRYNNAAKSLRDAIYSVYSEGKYLTPDVGGSSTTDEMISAIRSKI 336 >1IDM-A nrPDB Length = 343 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 102/347 (29%), Positives = 159/347 (45%), Gaps = 23/347 (6%) Query: 55 HTVTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNA----DEEDIRNAIMA 106 V ++PGDGIGPE+ V + + +E A E Sbjct: 1 MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKG 60 Query: 107 IRRNRVALKGNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRHK----- 159 + L G++ S + +L R S DL+AN+ K PG+ Sbjct: 61 VEEAEAVLLGSVGGPKWGTGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 120 Query: 160 --DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVT 217 +D+LIVRE T G Y + + +K + R+A AF+ A++ RK V Sbjct: 121 ARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKHVV 179 Query: 218 AVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYG 277 +V KAN++++G+ + + EV YP + E+ VD M LV P +FDV+V N++G Sbjct: 180 SVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFG 238 Query: 278 NIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLD 337 +I++++ + L G GL+ A+ G VFE + IA K IANPTA +L++ MML+ Sbjct: 239 DILSDLASVLPGSLGLLPSASLGRGTPVFEP-VHGSAPDIAGKGIANPTAAILSAAMMLE 297 Query: 338 H-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 H L A + AV ++ PD+GG T V+RH+ Sbjct: 298 HAFGLVELARKVEDAVAKALLE--TPPPDLGGSAGTEAFTATVLRHL 342 >1AI3-A nrPDB Length = 416 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 94/393 (23%), Positives = 161/393 (40%), Gaps = 67/393 (17%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNADE------EDIR 101 + I GDGIG ++ + V A + + E++ + + Sbjct: 27 PIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPA 86 Query: 102 NAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSL---PGVVTRH 158 + IR RVA+KG + T + +S N LR LDLY + + P V Sbjct: 87 ETLDLIREYRVAIKGPLTTP--VGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHP 144 Query: 159 KDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKA 195 + D++I REN+E Y+ +E ++ + E +K ++ Sbjct: 145 ELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEE 204 Query: 196 KSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY------------ 243 + R+ A + A + R VT VHK NIMK +G F ++A Sbjct: 205 GTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWL 264 Query: 244 --------PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVA 295 +I +++I D Q++ RP ++DV+ NL G+ +++ A VGG G+ Sbjct: 265 KVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAP 324 Query: 296 GANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS 355 GAN G A+FE AT T A ++ NP + +L++ MML H+ A I K + + Sbjct: 325 GANIGDECALFE-ATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGA 383 Query: 356 MDNENM-----HTPDIGGQGTTSEAIQDVIRHI 383 ++ + + D SE +I ++ Sbjct: 384 INAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >3VMJ-A nrPDB Length = 375 Score = 359 bits (922), Expect = e-100, Method: Composition-based stats. Identities = 101/358 (28%), Positives = 169/358 (47%), Gaps = 34/358 (9%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRH----ACVPVDFEEVHVSSNADEE----DIRNAIMA 106 + + ++ GDGIGPE+M + V + + +++ E V A + + Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV------ 155 L G++ LPP+ + L R +L+ N+ K G+ Sbjct: 74 CEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLR 133 Query: 156 --TRHKDIDILIVRENTEGEYSSLE----HESVAGVVESLKIITKAKSLRIAEYAFKLAQ 209 + D+L VRE T G Y E + ++ + RIA AF+ A+ Sbjct: 134 SDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREISRIARIAFEAAR 193 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 RKKVT+V KAN++ L+ Q EVA +P + E++ +DN TMQL+ RP +FDV Sbjct: 194 GR-RKKVTSVDKANVLACS-VLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDV 251 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTAT 328 M+ NL+G+I+++ A L G GL++ A+ + +FE A + IA K IANP A Sbjct: 252 MLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAG-GSAPDIAGKGIANPIAQ 310 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDN----ENMHTPDIGGQGTTSEAIQDVIR 381 +L++ +ML H LK A++I +AV ++++ + + D + T+ + D I Sbjct: 311 ILSAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQRHKAKTTVQMGDFIA 368 >3VML-A nrPDB Length = 375 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 104/358 (29%), Positives = 169/358 (47%), Gaps = 34/358 (9%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRH----ACVPVDFEEVHVSSNADEE----DIRNAIMA 106 + + ++ GDGIGPE+M + V + + +++ E V A + + Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV------ 155 L G++ +LPP+ + L R +L+ N+ K PG+ Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 156 --TRHKDIDILIVRENTEGEYSSLE----HESVAGVVESLKIITKAKSLRIAEYAFKLAQ 209 K DIL VRE T G Y E ++ + RIA+ AF+ AQ Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKGRQGEGENEEAFDTMRYSRKEIRRIAKIAFESAQ 193 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 RKKVT+V KAN++ L+ + EVA YP + E++ +DN TMQL+ RP +FDV Sbjct: 194 GR-RKKVTSVDKANVLACS-VLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFDV 251 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTAT 328 M+ NL+G+IV++ A L G GL+A + + ++E A + IA + IANP A Sbjct: 252 MLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAG-GSAPDIAGQGIANPVAQ 310 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDN----ENMHTPDIGGQGTTSEAIQDVIR 381 +L++ ++L H LKL A +I AV ++++ + + D + T+ + D I Sbjct: 311 ILSAALLLRHSLKLEDAALAIEAAVSKALNSGYLTGELLSSDQRHKAKTTVQMGDFIA 368 >2E5M-A nrPDB Length = 409 Score = 358 bits (920), Expect = 2e-99, Method: Composition-based stats. Identities = 108/390 (27%), Positives = 176/390 (45%), Gaps = 61/390 (15%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNAD----EEDIRN 102 + + I GDGIGPE+ V A + + EV+ A+ + + Sbjct: 24 KPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSREIKWLEVYAGEKAEKLVNDRFPKE 83 Query: 103 AIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPG---VVTRHK 159 + + RV LKG +ET + KS N +R LDLYAN+ K + G + + Sbjct: 84 TQEMLLKYRVVLKGPLETP--IGKGWKSVNVAIRLMLDLYANIRPVKYIEGLESPLKHPE 141 Query: 160 DIDILIVRENTEGEYSSLEH--------------------ESVAGVVESLKIITKAKSLR 199 +D++I RENT+ Y +E+ E +K+++K K+ R Sbjct: 142 KVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKELKVEIEDDTGIGIKVMSKYKTQR 201 Query: 200 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA-ARY--------------- 243 I A + A E RKKVT +HK N+MK +G F + EVA Y Sbjct: 202 ITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYEVALKEYRDFIVTEEEINQGKP 261 Query: 244 --PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGH 301 +I + I DN Q++ RP+++D+++ PN+ G+ +++ L+G G++ GAN G Sbjct: 262 DQGKIILNDRIADNMFQQIIIRPEEYDIILAPNVNGDYISDAAGALIGNIGMLGGANIGD 321 Query: 302 VYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENM 361 +FE A T A KN+ANPT + A +ML + + A I KA+ ++ ++ + Sbjct: 322 EGGMFE-AIHGTAPKYAGKNVANPTGIIKAGELMLRWMGWNEAADLIEKAINMAIRDKKV 380 Query: 362 HTPDIG-----GQGTTSEAIQDVIRHIRVI 386 T DI T E ++I+ + I Sbjct: 381 -TQDIARFMGVKALGTKEYADELIKIMDTI 409 >6C0E-A nrPDB Length = 419 Score = 358 bits (919), Expect = 2e-99, Method: Composition-based stats. Identities = 96/393 (24%), Positives = 172/393 (43%), Gaps = 67/393 (17%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNA------DEEDIR 101 + I GDGIG ++ + V A + + EV+ A D+ + Sbjct: 30 PIIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPK 89 Query: 102 NAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCK---SLPGVVTRH 158 + A+++ V++KG + T + +S N +R +DLY + + +P V Sbjct: 90 ETLDAMKKYVVSIKGPLTTP--VGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREP 147 Query: 159 KDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKA 195 D++I REN+E Y+ +E ++ + +K +++ Sbjct: 148 WKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSRE 207 Query: 196 KSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA------ARY---PQI 246 + R+ + A + A ++ R VT VHK NIMK +G F +VA Y P + Sbjct: 208 GTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWM 267 Query: 247 TFE-----------NMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVA 295 F+ ++I D Q++ RP+ + V+ NL G+ +++ A VGG G+ Sbjct: 268 EFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGDYISDALAAQVGGIGIAP 327 Query: 296 GANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS 355 GAN AVFE AT T A +N NP + +L++ MML H+ + A I + + + Sbjct: 328 GANISDQMAVFE-ATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGA 386 Query: 356 MDNENM-HTPDIGGQGTT----SEAIQDVIRHI 383 ++ + + + + G QG T S +I+H+ Sbjct: 387 IEAKTVTYDFERGMQGATLVSSSGFADAMIKHM 419 >5M2E-A nrPDB Length = 418 Score = 358 bits (919), Expect = 2e-99, Method: Composition-based stats. Identities = 97/393 (24%), Positives = 163/393 (41%), Gaps = 67/393 (17%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNA------DEEDIR 101 + I GDGIG ++ + V A + + EV+ A D + Sbjct: 29 PIIPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQ 88 Query: 102 NAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCK---SLPGVVTRH 158 + A+R V++KG + T + +S N LR LDLY + +P V + Sbjct: 89 ETLDAVRDYVVSIKGPLTTP--VGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVKKP 146 Query: 159 KDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKA 195 D+D++I REN+E Y+ +E ++ + E +K +++ Sbjct: 147 GDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQE 206 Query: 196 KSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY---------PQ- 245 + R+ A + A ++ R VT VHK NIMK +G F EVA P Sbjct: 207 GTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELLDGGPWM 266 Query: 246 ----------ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVA 295 + +++I D Q++ RP ++DV+ NL G+ +++ A VGG G+ Sbjct: 267 QFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATLNLNGDYLSDALAAEVGGIGIAP 326 Query: 296 GANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLAS 355 GAN A+FE AT T A ++ NP + +L++ MML H+ A I K + Sbjct: 327 GANLSDSVAMFE-ATHGTAPKYAGQDKVNPGSLILSAEMMLRHMGWTEAADLIIKGTNGA 385 Query: 356 MDNENM-----HTPDIGGQGTTSEAIQDVIRHI 383 + + + D + SE +I + Sbjct: 386 IAAKTVTYDFERLMDGATLLSCSEFGDAMIAKM 418 >1VLC-A nrPDB Length = 366 Score = 357 bits (917), Expect = 4e-99, Method: Composition-based stats. Identities = 99/351 (28%), Positives = 158/351 (45%), Gaps = 30/351 (8%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFR----HACVPVDFEEVHVSSNADEE----DIRNAIMA 106 + ++PGDGIGPE++ V + H+ +A + Sbjct: 13 MKIAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGGDAIDRFGEPLPEETKKI 72 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNN---ILRTSLDLYANVIHCKSLPGVVTRHK-- 159 G++ +LPP + LR L+LYAN+ K +V Sbjct: 73 CLEADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVYRSLVHVSPLK 132 Query: 160 ------DIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGR 213 +D++ VRE + G Y I + RIA AF++A+ R Sbjct: 133 EKVIGSGVDLVTVRELSYGVYYGQPRGLDEEKGFDTMIYDRKTVERIARTAFEIAKNR-R 191 Query: 214 KKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMP 273 KKVT+V KAN++ L+ + EVA YP + ++ VDN MQL+ +P QFDV++ Sbjct: 192 KKVTSVDKANVL-YSSMLWRKVVNEVAREYPDVELTHIYVDNAAMQLILKPSQFDVILTT 250 Query: 274 NLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASC 333 N++G+I+++ A L G GL+ A++G ++E A + IA KNIANP A +L+ Sbjct: 251 NMFGDILSDESAALPGSLGLLPSASFGDK-NLYEPAG-GSAPDIAGKNIANPIAQILSLA 308 Query: 334 MMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIG---GQGTTSEAIQDVI 380 MML+H + A I +AV + E T DI + ++ + D+I Sbjct: 309 MMLEHSFGMVEEARKIERAVELVI-EEGYRTRDIAEDPEKAVSTSQMGDLI 358 >3VMK-A nrPDB Length = 375 Score = 356 bits (915), Expect = 7e-99, Method: Composition-based stats. Identities = 103/359 (28%), Positives = 165/359 (45%), Gaps = 34/359 (9%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRH----ACVPVDFEEVHVSSNADEE----DIRNAIMA 106 + + ++ GDGIGPE+M + V + +++ E V A + + Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRFDLSIEYSEYDVGGAAIDNHGCPLPEATLKG 73 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGVV------ 155 L G++ +LPP+ + L R +L+ N+ K PG+ Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 156 --TRHKDIDILIVRENTEGEYSSLE----HESVAGVVESLKIITKAKSLRIAEYAFKLAQ 209 K DIL VRE T G Y E ++ + RIA+ AF+ AQ Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKGRQGEGENEEAFDTMRYSRKEIRRIAKIAFESAQ 193 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 RKKVT+V KAN++ L+ + EVA YP + E++ +DN TMQL+ RP +FDV Sbjct: 194 GR-RKKVTSVDKANVLACS-VLWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFDV 251 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRNTGKSIANKNIANPTAT 328 M+ NL+G+IV++ A L G GL+A + + ++E A + IA + IANP A Sbjct: 252 MLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGMYEPAG-GSAPDIAGQGIANPVAQ 310 Query: 329 LLASCMMLDH-LKLHSYATSIRKAVLASMDNE----NMHTPDIGGQGTTSEAIQDVIRH 382 +L++ ++L H LKL A +I AV ++ + + Q ++ + D I Sbjct: 311 ILSAALLLRHSLKLEDAALAIEAAVSKALSDGYLTCELLPASERSQAKSTSQMGDYIAQ 369 >3TY3-A nrPDB Length = 366 Score = 354 bits (909), Expect = 4e-98, Method: Composition-based stats. Identities = 106/358 (29%), Positives = 169/358 (47%), Gaps = 31/358 (8%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRNRV- 112 R + +IP DGIG E++ + + + + + +A A+ V Sbjct: 10 RIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPERTVE 69 Query: 113 --------ALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDIL 164 AL G +++ + + S LR + LYANV KSL G + +D++ Sbjct: 70 RLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKGKP--VDLV 127 Query: 165 IVRENTEGEYSSLEHES----VAGVVESLKIITKAKSLRIAEYAFKLAQES--------- 211 IVRENTE Y E V E+++ I++ S +I + AF++A+ Sbjct: 128 IVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRESGTY 187 Query: 212 ---GRKKVTAVHKANIMKLGDGLFLQCCREVAA---RYPQITFENMIVDNTTMQLVSRPQ 265 + VT +HK+N+M + DGLF + CR + Y I + IVD+ +L P+ Sbjct: 188 SIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFREPE 247 Query: 266 QFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANP 325 FDV+V PNLYG+I+++ A L+G GLV AN G + + E + IA + IANP Sbjct: 248 CFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDNFVMSEP-VHGSAPDIAGRGIANP 306 Query: 326 TATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHI 383 AT + +ML+ + A I AV + + TPD+GG+ T+E V+ +I Sbjct: 307 VATFRSVALMLEFMGHQDAAADIYTAVDKVLTEGKVLTPDLGGKSGTNEITDAVLANI 364 >1HQS-A nrPDB Length = 423 Score = 351 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 101/407 (24%), Positives = 171/407 (42%), Gaps = 82/407 (20%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNA----DEEDIRNA 103 + I GDG GP++ V A + ++EV+ A E Sbjct: 20 PIIPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAET 79 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCK---SLPGVVTRHKD 160 + IR +A+KG + T + +S N LR LDL+ + + +P V R +D Sbjct: 80 LDVIREYFIAIKGPLTTP--VGGGIRSLNVALRQELDLFVCLRPVRYFTGVPSPVKRPED 137 Query: 161 IDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITKAKS 197 D++I RENTE Y+ +E+ + V+ +K +++ + Sbjct: 138 TDMVIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKIRFPETSGIGIKPVSEEGT 197 Query: 198 LRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA-ARYPQ----------- 245 R+ A A E GRK VT VHK NIMK +G F E+A Y Sbjct: 198 SRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAEKEYGDKVFTWAQYDRI 257 Query: 246 ---------------------ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVC 284 I ++ I D Q+++RP +FDV+ NL G+ +++ Sbjct: 258 AEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEFDVVATMNLNGDYISDAL 317 Query: 285 AGLVGGPGLVAGANYG--HVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLH 342 A VGG G+ GAN +A+FE AT T A + NP++ +L+ ++L+HL + Sbjct: 318 AAQVGGIGIAPGANINYETGHAIFE-ATHGTAPKYAGLDKVNPSSVILSGVLLLEHLGWN 376 Query: 343 SYATSIRKAVLASMDNENMHTPDI------GGQGTTSEAIQDVIRHI 383 A + K++ ++ + + T D + SE +++I+++ Sbjct: 377 EAADLVIKSMEKTIAS-KVVTYDFARLMDGATEVKCSEFGEELIKNM 422 >2D4V-A nrPDB Length = 429 Score = 351 bits (901), Expect = 3e-97, Method: Composition-based stats. Identities = 101/407 (24%), Positives = 171/407 (42%), Gaps = 82/407 (20%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHACVP-------VDFEEVHVSSNA------DEEDI 100 + + I GDGIG ++ ++SV A + + E+ A + Sbjct: 26 QPIIPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQYLP 85 Query: 101 RNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSL---PGVVTR 157 + AIR +VA+KG +ET + +S N +R LDLY + + P + Sbjct: 86 DETMAAIREYKVAIKGPLETP--VGGGIRSLNVAMRQDLDLYVCLRPVRYFEGTPSPMRH 143 Query: 158 HKDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITK 194 + +D++I REN+E Y+ +E + + E +K ++ Sbjct: 144 PEKVDMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVST 203 Query: 195 AKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY----------- 243 S R+ + A E G+ V+ VHK NIMK +G F +A R Sbjct: 204 EGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGYALAEREFAGRVFTWRQK 263 Query: 244 ----------------------PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVN 281 ++ +++I DN Q++ RP+ + V+ NL G+ V+ Sbjct: 264 AAISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRPEDYSVVATLNLNGDYVS 323 Query: 282 NVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKL 341 + A VGG G+ GAN +A+FE AT T IA + ANP++ +L++ MML+HL Sbjct: 324 DALAAEVGGIGMAPGANLSDTHAIFE-ATHGTAPDIAGQGKANPSSLILSAVMMLEHLGW 382 Query: 342 HSYATSIRKAVLASMDNENMHTPDIGG------QGTTSEAIQDVIRH 382 A +I A+ A++ + T D+ +T+E +IR Sbjct: 383 GEAAQAIVAAMNATIAAGEV-TGDLAALRGDVPALSTTEFTAALIRR 428 >3DMS-A nrPDB Length = 427 Score = 351 bits (900), Expect = 4e-97, Method: Composition-based stats. Identities = 91/367 (24%), Positives = 153/367 (41%), Gaps = 62/367 (16%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHAC-------VPVDFEEVHVSSNA------DEEDI 100 + + I GDG G ++ + V A + + E++ A D Sbjct: 36 QPIIPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKIHWMEIYAGEKATKVYGPDVWLP 95 Query: 101 RNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIH---CKSLPGVVTR 157 + ++ V++KG + T + +S N LR LDLY + K +P V Sbjct: 96 EETLQVLKEYVVSIKGPLTTP--VGGGIRSLNVALRQELDLYVCLRPIQYFKGVPSPVRE 153 Query: 158 HKDIDILIVRENTEGEYSSLEHESVAGVVE-----------------------SLKIITK 194 + +++I REN+E Y+ +E + + + +K ++K Sbjct: 154 PEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEMGVKKIRFPQTSGIGIKPVSK 213 Query: 195 AKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY---------PQ 245 + R+ A + A ++ RK VT VHK NIMK +G F +A + P Sbjct: 214 EGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRDAGYALAQKEFGAELIDGGPW 273 Query: 246 -----------ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLV 294 I ++ I D Q++ RP ++DV+ NL G+ +++ A VGG G+ Sbjct: 274 MKFKNPKTGNEIVVKDSIADAFLQQILLRPAEYDVIATLNLNGDYISDALAAQVGGIGIA 333 Query: 295 AGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLA 354 GAN A+FE AT T A K+ NP + +L++ MML HL A I A+ Sbjct: 334 PGANLSDSVAMFE-ATHGTAPKYAGKDYVNPGSEILSAEMMLRHLGWTEAADVIISAMEK 392 Query: 355 SMDNENM 361 S+ + + Sbjct: 393 SIKQKRV 399 >5J32-A nrPDB Length = 403 Score = 350 bits (898), Expect = 6e-97, Method: Composition-based stats. Identities = 100/359 (27%), Positives = 174/359 (48%), Gaps = 32/359 (8%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHAC----VPVDFEEVHVSSNADEE----DIRNAIM 105 R+T+T++PGDGIGPE++ K+V + A V +F E+ + A + I Sbjct: 40 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLPEETIS 99 Query: 106 AIRRNRVALKGNIE--TNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRH--- 158 A + + L G I N + +L R +L ++AN+ LP +V Sbjct: 100 AAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATVLPQLVDASTLK 159 Query: 159 ----KDIDILIVRENTEGEYSSLEH-----ESVAGVVESLKIITKAKSLRIAEYAFKLAQ 209 + +D+++VRE T G Y E+ V + ++ + RIA AF+ A+ Sbjct: 160 REVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARVAFETAR 219 Query: 210 ESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDV 269 + R K+ +V KAN+++ L+ + +A+ YP + +M VDN MQLV P+QFD Sbjct: 220 KR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRDPKQFDT 277 Query: 270 MVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATL 329 +V N++G+I+++ + + G G++ A+ + IA ++ ANP AT+ Sbjct: 278 IVTNNIFGDILSDEASMITGSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQDKANPLATI 337 Query: 330 LASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGT----TSEAIQDVIRHI 383 L++ M+L + L A I AVL +++N T DI GT E ++V++ + Sbjct: 338 LSAAMLLKYGLGEEKAAKRIEDAVLVALNN-GFRTGDIYSAGTKLVGCKEMGEEVLKSV 395 >1V5B-A nrPDB Length = 366 Score = 348 bits (893), Expect = 2e-96, Method: Composition-based stats. Identities = 97/358 (27%), Positives = 169/358 (47%), Gaps = 32/358 (8%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVF----RHACVPVDFEEVHVSSNADEE----DIRNAIM 105 + + ++PGDGIGPE+M V + FE + A +E + Sbjct: 2 KMKLAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETLD 61 Query: 106 AIRRNRVALKGNI--ETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRHK-- 159 RR+ L G + + P S + +L R + L+AN+ K+ ++ Sbjct: 62 ICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAYATLLNASPLK 121 Query: 160 -----DIDILIVRENTEGEYSSLEHES---VAGVVESLKIITKAKSLRIAEYAFKLAQES 211 ++D++IVRE T G Y E V T+ + RI E AF+LAQ Sbjct: 122 RERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTLAYTREEIERIIEKAFQLAQIR 181 Query: 212 GRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMV 271 RKK+ +V KAN+++ ++ + E A +YP + +M+VD+T MQL++ P QFDV+V Sbjct: 182 -RKKLASVDKANVLE-SSRMWREIAEETAKKYPDVELSHMLVDSTAMQLIANPGQFDVIV 239 Query: 272 MPNLYGNIVNNVCAGLVGGPGLVAGANY-GHVYAVFETATRNTGKSIANKNIANPTATLL 330 N++G+I++++ + + G G++ A+ + ++E + IA + ANP T+L Sbjct: 240 TENMFGDILSDLASVITGSLGMLPSASLRSDRFGMYEP-VHGSAPDIAGQGKANPLGTVL 298 Query: 331 ASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDI----GGQGTTSEAIQDVIRHI 383 ++ +ML + L A +I KAV + + T D+ G +T E +I + Sbjct: 299 SAALMLRYSFGLEKEAAAIEKAVDDVL-QDGYCTGDLQVANGKVVSTIELTDRLIEKL 355 >5HN5-A nrPDB Length = 353 Score = 345 bits (885), Expect = 2e-95, Method: Composition-based stats. Identities = 111/336 (33%), Positives = 174/336 (51%), Gaps = 19/336 (5%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEE----DIRNAIMAIRRN 110 + V +IPGDGIGPE++ V + V FE + +E + IRR+ Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAVTGRVRFEYYEGGVDVFQECGSPIREEDLEEIRRS 61 Query: 111 RVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENT 170 L G T +LP ++S LR L LYAN+ +P + T + I+IVREN+ Sbjct: 62 DAVLFGATTTPFDLP-GYRSLILTLRKELGLYANLR---IIPDLRTGRE---IVIVRENS 114 Query: 171 EGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDG 230 EG Y + V G +++IT+ + RIA +A + A+ G +T VHKAN++ GD Sbjct: 115 EGLYFGI-GAVVNGRAVDVRLITREGAERIARFAVEQAKARG-SFITFVHKANVLT-GDK 171 Query: 231 LFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGG 290 F + REVA + + I+D+ T++LV P + V++ NL+G+I++++ G Sbjct: 172 FFRRIVREVAGEEG-VEVRDAIIDSFTIKLVRNPWEHGVILSENLFGDILSDLATVHAGS 230 Query: 291 PGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRK 350 G+V NYG A+FE + IA K IANP +L+ M+LD+L L + IR Sbjct: 231 IGIVPSGNYGDGIALFEP-VHGSAPDIAGKGIANPIGAILSGAMLLDYLGLD--GSLIRA 287 Query: 351 AVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 386 AV + N + TPD+GG+ T + ++ +I I + Sbjct: 288 AVRGYVVNGEL-TPDMGGRARTEDVVRGIIGEIEDL 322 >1A05-A nrPDB Length = 358 Score = 341 bits (876), Expect = 3e-94, Method: Composition-based stats. Identities = 100/361 (27%), Positives = 166/361 (45%), Gaps = 32/361 (8%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRH----ACVPVDFEEVHVSSNA----DEEDIRNAIMA 106 + + GDGIGPE++ + V A + + E V A D+ ++ Sbjct: 2 KKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQL 61 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNILR--TSLDLYANVIHCKSLPGVVTRHK--- 159 + G + PP+ + +LR LDLYAN+ + P ++ Sbjct: 62 AMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRP 121 Query: 160 ----DIDILIVRENTEGEYSSLEH--ESVAGVVESLK--IITKAKSLRIAEYAFKLAQES 211 D+DIL+VRE T Y E + G + + + RIA AF+ AQ Sbjct: 122 ELVRDVDILVVRELTGDIYFGQPRGLEVIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQGR 181 Query: 212 GRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMV 271 RK++ +V KAN+++ L+ + EVA YP + +M VDN MQL+ P QFDV++ Sbjct: 182 -RKQLCSVDKANVLETT-RLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFDVLL 239 Query: 272 MPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLA 331 N++G+I+++ + L G G++ A+ G A++E + IA ++ ANP AT+L+ Sbjct: 240 TGNMFGDILSDEASQLTGSIGMLPSASLGEGRAMYEP-IHGSAPDIAGQDKANPLATILS 298 Query: 332 SCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGT----TSEAIQDVIRHIRVI 386 MML H L +A + AV + ++ + T DI GT T V+ + + Sbjct: 299 VAMMLRHSLNAEPWAQRVEAAVQRVL-DQGLRTADIAAPGTPVIGTKAMGAAVVNALNLK 357 Query: 387 N 387 + Sbjct: 358 D 358 >4IWH-A nrPDB Length = 363 Score = 340 bits (873), Expect = 5e-94, Method: Composition-based stats. Identities = 90/350 (25%), Positives = 145/350 (41%), Gaps = 28/350 (8%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSSNADEE----DIRNAIMAIRRN 110 + ++PGDGIGPE++ V + E V E + + Sbjct: 9 MKIAVLPGDGIGPEIVNEAVKVLNALDEKFELEHAPVGGAGYEASGHPLPDATLALAKEA 68 Query: 111 RVALKGNIETN--HNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVTRHK------- 159 L G + +L + + IL R L+L+AN P +V Sbjct: 69 DAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVA 128 Query: 160 DIDILIVRENTEGEYSSLEHESVA-------GVVESLK--IITKAKSLRIAEYAFKLAQE 210 +DILIVRE Y A G E ++ + RIA AF+ AQ+ Sbjct: 129 GLDILIVRELNGDIYFGQPRGVRAAPDGPFAGEREGFDTMRYSEPEVRRIAHVAFQAAQK 188 Query: 211 SGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVM 270 KK+ +V K+N+++ + +V+ Y + +M VDN MQL P+QFDV+ Sbjct: 189 RA-KKLLSVDKSNVLE-TSQFWRDVMIDVSKEYADVELSHMYVDNAAMQLAKAPKQFDVI 246 Query: 271 VMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLL 330 V N++G+I+++ + L G G++ A+ + + IA K IANP AT+L Sbjct: 247 VTGNMFGDILSDEASMLTGSIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGIANPLATIL 306 Query: 331 ASCMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDV 379 ++ M+L + L A I +AV + + T DI G + Sbjct: 307 SAAMLLRYSLNRAEQADRIERAVKTVL-EQGYRTGDIATPGCRQVGTAAM 355 >3FMX-X nrPDB Length = 364 Score = 338 bits (868), Expect = 2e-93, Method: Composition-based stats. Identities = 91/361 (25%), Positives = 160/361 (44%), Gaps = 30/361 (8%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVP---------VDFEEVHVSSNADEEDIRNAIM 105 + IPGDGIG E++ V A + ++ + + Sbjct: 6 FRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDYYLQHGKMMPDDWAE 65 Query: 106 AIRRNRVALKGNIETNHNLPPSHKSRNNIL--RTSLDLYANVIHCKSLPGVVT-----RH 158 +++ G + +P ++L R D Y N+ + PGV + Sbjct: 66 QLKQYDAIYFGAVGWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALANRKV 125 Query: 159 KDIDILIVRENTEGEYSSLEHESVA----GVVESLKIITKAKSLRIAEYAFKLAQESGRK 214 DID ++VRENTEGEYSSL +V I T+ RI +YAF LA++ RK Sbjct: 126 GDIDFVVVRENTEGEYSSLGGIMFENTENEIVIQESIFTRRGVDRILKYAFDLAEKRERK 185 Query: 215 KVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPN 274 VT+ K+N M + + + +AA YP ++++ +D + V +P++FDV+V N Sbjct: 186 HVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFDVVVASN 245 Query: 275 LYGNIVNNVCAGLVGGPGLVAGANYG---HVYAVFETATRNTGKSIANKNIANPTATLLA 331 L+G+I++++ G G+ AN + ++FE + I KNIANP A + + Sbjct: 246 LFGDILSDLGPACAGTIGIAPSANLNPERNFPSLFEP-VHGSAPDIFGKNIANPIAMIWS 304 Query: 332 SCMMLDHLK-----LHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 386 +ML+ L + A+ + + ++ TPD+GG +T + + + + Sbjct: 305 GALMLEFLGQGDERYQRAHDDMLNAIERVIADGSV-TPDMGGTLSTQQVGAAISDTLARL 363 Query: 387 N 387 + Sbjct: 364 D 364 >1XGV-A nrPDB Length = 435 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 102/394 (25%), Positives = 170/394 (43%), Gaps = 65/394 (16%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPV--------DFEEVH---VSSNADEEDIRNA 103 V I GDG+GPE++ V A V +E + E + Sbjct: 36 PVVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIVWWELLAGHLAREKCGELLPKAT 95 Query: 104 IMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSL--PGVVTRHKDI 161 + IR RVALKG +ET + ++S N +R +LDLYAN+ + P + Sbjct: 96 LEGIRLARVALKGPLETP--VGTGYRSLNVAIRQALDLYANIRPVRYYGQPAPHKYADRV 153 Query: 162 DILIVRENTEGEYSSLEHE--------------------SVAGVVESLKIITKAKSLRIA 201 D++I RENTE Y+ +E +K I++ + R+ Sbjct: 154 DMVIFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIREDAGIGVKPISRFATRRLM 213 Query: 202 EYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAAR------------------- 242 E A + A +G VT +HK NIMK +G F++ EVA Sbjct: 214 ERALEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYEVALEKFREHVVTEQEVQEKYGGV 273 Query: 243 --YPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG 300 +I + I DN Q+++RP + V+V PNL G+ +++ + LVGG G+ AG N G Sbjct: 274 RPEGKILVNDRIADNMLQQIITRPWDYQVIVAPNLNGDYISDAASALVGGIGMAAGMNMG 333 Query: 301 HVYAVFETATRNTGKSIANKNIANPTATLLASCMML-DHLKLHSYATSIRKAVLASMDNE 359 AV E T A K++ NP+A +L++ +++ + + + + A+ ++ ++ Sbjct: 334 DGIAVAEP-VHGTAPKYAGKDLINPSAEILSASLLIGEFMGWREVKSIVEYAIRKAVQSK 392 Query: 360 NMHTPDIG------GQGTTSEAIQDVIRHIRVIN 387 + T D+ TSE + +I +I + Sbjct: 393 KV-TQDLARHMPGVQPLRTSEYTETLIAYIDEAD 425 >3UDO-A nrPDB Length = 361 Score = 335 bits (860), Expect = 2e-92, Method: Composition-based stats. Identities = 97/353 (27%), Positives = 159/353 (45%), Gaps = 29/353 (8%) Query: 55 HTVTMIPGDGIGPELMLHVKSVFRHACVPVDFE----EVHVSSNADEE----DIRNAIMA 106 + V ++ GDGIGP +M + +F E + + + + Sbjct: 7 YKVAVLAGDGIGPLVMKEALKILTFIAQKYNFSFELNEAKIGGASIDAYGVALSDETLKL 66 Query: 107 IRRNRVALKGNI--ETNHNLPPSHKSRNNIL---RTSLDLYANVIHCKSLPGV------- 154 ++ L G++ NLP + L R +L+AN+ CK + Sbjct: 67 CEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLK 126 Query: 155 -VTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGR 213 K +DIL VRE T G Y + ++ +I TK + RIA AF+ A+ + Sbjct: 127 NEIIQKGVDILCVRELTGGIYFGKQDLGKESAYDT-EIYTKKEIERIARIAFESARIR-K 184 Query: 214 KKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMP 273 KKV + KAN++ L+ + VA Y I E M VDN MQ+V P FDVM+ Sbjct: 185 KKVHLIDKANVLA-SSILWREVVANVAKDYQDINLEYMYVDNAAMQIVKNPSIFDVMLCS 243 Query: 274 NLYGNIVNNVCAGLVGGPGLVAGANYGH-VYAVFETATRNTGKSIANKNIANPTATLLAS 332 NL+G+I+++ A + G GL++ A+ + ++E A + IA+ NIANP A +L++ Sbjct: 244 NLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAG-GSAPDIAHLNIANPIAQILSA 302 Query: 333 CMMLDH-LKLHSYATSIRKAVLASMDNENMHTPDIGGQG-TTSEAIQDVIRHI 383 +ML + K A I A+ ++ M T D+ + ++ + D I I Sbjct: 303 ALMLKYSFKEEQAAQDIENAISLALAQGKM-TKDLNAKSYLNTDEMGDCILEI 354 >2G4O-A nrPDB Length = 337 Score = 306 bits (784), Expect = 1e-83, Method: Composition-based stats. Identities = 94/330 (28%), Positives = 157/330 (47%), Gaps = 20/330 (6%) Query: 56 TVTMIPGDGIGPELMLHVKSVFRHAC---VPVDFEEVHVSSNADEEDIRNAIMAIRRNRV 112 + +I GDGIGPE+ V ++ +A E + ++++A RN Sbjct: 3 KLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD 62 Query: 113 ALKGNIETNHNLPPSHKSRNNILRTSL--DLYANVIHCKSLPG---VVTRHKDIDILIVR 167 A+ + ++P R +LR D + N+ + PG ++ + ID ++VR Sbjct: 63 AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR 122 Query: 168 ENTEGEYSSLEHESVAG----VVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKAN 223 E TEG Y+ G V + + T R+ AF+ A+ RK +T VHK N Sbjct: 123 EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKTN 181 Query: 224 IMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNV 283 ++ GL+L+ EV YP + VD T+ +++ P +FDV+V NL+G+I+ ++ Sbjct: 182 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDL 241 Query: 284 CAGLVGGPGLVAGANYGHVYA---VFETATRNTGKSIANKNIANPTATLLASCMMLDHLK 340 A + GG GL A N A +FE + IA + IA+PTA +++ ++L HL Sbjct: 242 AAAVCGGIGLAASGNIDATRANPSMFEP-VHGSAPDIAGQGIADPTAAIMSVALLLSHLG 300 Query: 341 LHSYATSIRKAVL---ASMDNENMHTPDIG 367 H A + +AV A+ +E + T D+G Sbjct: 301 EHDAAARVDRAVEAHLATRGSERLATSDVG 330 >1ZOR-A nrPDB Length = 399 Score = 81.5 bits (200), Expect = 5e-16, Method: Composition-based stats. Identities = 71/394 (18%), Positives = 140/394 (35%), Gaps = 69/394 (17%) Query: 57 VTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVS----SNADEEDIRNAIMAIRRNRV 112 + + GD + + +K + + + D++ A AI++ V Sbjct: 10 IVELDGDEMARVMWKMIKEKLILPYLDIQLVYFDLGIKKRDETDDQITIEAAKAIKKYGV 69 Query: 113 ALKGNIETNH-------NLPPSHKSRNNILRTSLD--LYANVIHCKSLPGVVTRHKDIDI 163 +K T NL + KS N +R LD ++ I K++P +V R K I Sbjct: 70 GVKCATITPDAERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLVKRWKK-PI 128 Query: 164 LIVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFK-----LAQESGRKKVTA 218 +I R Y+++E V G E ++ ++ + + F+ +A + K + + Sbjct: 129 IIGRHAYGDIYNAVE-AKVEGPAEVELVVRNKENKTLLVHKFEGNGVVMAMHNLEKSIRS 187 Query: 219 ------------------VHKANIMKLGDGLFLQCC-REVAA-----RYPQITFENMIVD 254 K I K+ F EV + + M++D Sbjct: 188 FAQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKRKEELEKAGVNYRYMLID 247 Query: 255 NTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRNT 313 + Q++ + N G+I++++ A G GL+ FE A T Sbjct: 248 DAAAQILRSEGGM-LWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDGVYEFEAA-HGT 305 Query: 314 GKS-----IAN-KNIANPTATLLASCMMLDHLKLH-------SYATSIRKAVLASMDNEN 360 + + K NPTA++ A + +A + KAV+ ++++ Sbjct: 306 VRRHYYRYLKGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKAVINTIES-G 364 Query: 361 MHTPDIGG--------QGTTSEAIQDVIRHIRVI 386 + T D+ T E I +V +++ + Sbjct: 365 VITKDLQPFTEPPIDKYVTLEEFIDEVKKNLEKL 398 >2QFY-A nrPDB Length = 427 Score = 80.8 bits (198), Expect = 9e-16, Method: Composition-based stats. Identities = 69/402 (17%), Positives = 132/402 (32%), Gaps = 74/402 (18%) Query: 54 RHTVTMIPGDGIGPELMLHVKS--VFRHACVPVDF--EEVHVSSNADEEDIRNAIMAIRR 109 + V + GD + + +K + + V + + V ++ ++A AI++ Sbjct: 22 KQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQDAAEAIKK 81 Query: 110 NRVALKGNIETNH-------NLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDID 162 V +K T NL KS N +R L +P + + Sbjct: 82 YGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTV-FREPIVIPRIPRLVPRWE 140 Query: 163 --ILIVRENTEGEYSS---------------LEHESVAGVVESLKII------------- 192 I+I R +Y + + ++LK+ Sbjct: 141 KPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSGVAMAMYN 200 Query: 193 TKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAA-------RYPQ 245 T A +FKLA + + + K I+K DG F +EV Sbjct: 201 TDESIEGFAHSSFKLAIDK-KLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKSKFEQLG 259 Query: 246 ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAV 305 I +E+ ++D+ Q++ F +M + N G++ +++ A G GL+ Sbjct: 260 IHYEHRLIDDMVAQMIKSKGGF-IMALKNYDGDVQSDIVAQGFGSLGLMTSILVTPDGKT 318 Query: 306 FE-TATRNTGKSIANK------NIANPTATL--LASCMMLD-HLKLHSY----ATSIRKA 351 FE A T K N A++ + ++ L A + A Sbjct: 319 FESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFANILESA 378 Query: 352 VLASMDNENMHTPDIG---------GQGTTSEAIQDVIRHIR 384 L ++ + + T D+ TT E + V + ++ Sbjct: 379 TLNTVQQDGIMTKDLALACGNNERSAYVTTEEFLDAVEKRLQ 420 >5I96-A nrPDB Length = 458 Score = 73.1 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 79/457 (17%), Positives = 156/457 (34%), Gaps = 96/457 (21%) Query: 10 GSAAKAVLGPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPEL 69 S ++ PA L P + E P R+ ++++ I + ++ DG E+ Sbjct: 14 ASGSRPAWAPAALTAP----TSQEQPRRH-YADKRIKVAK--------PVVEMDG--DEM 58 Query: 70 MLHVKS-VFRHACVP---VDFEEVHVS----SNADEEDIRNAIMAIRRNRVALKGNIETN 121 + + +P + + + D++ ++ +A ++ VA+K T Sbjct: 59 TRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITP 118 Query: 122 H-------NLPPSHKSRNNILRTSLD--LYANVIHCKSLPGVVTR--------------- 157 L KS N ++ L ++ I CK++P +V Sbjct: 119 DEARVEEFKLKKMWKSPNGTIQNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQ 178 Query: 158 HKDIDILIVRENTEGEYSSL-------EHES----VAGVVESLKIITKAKSLRIAEYAFK 206 +K D + R T + E E GV + T A F+ Sbjct: 179 YKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGM-YNTDESISGFAHSCFQ 237 Query: 207 LAQESGRKKVTAVHKANIMKLGDGLFLQCCREV-AARYP------QITFENMIVDNTTMQ 259 A + + K I+K DG F +E+ Y +I +E+ ++D+ Q Sbjct: 238 YAIQKKWP-LYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 296 Query: 260 LVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANY-GHVYAVFETATRNTGKSI- 317 ++ F V N G++ +++ A G GL+ + A T Sbjct: 297 VLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355 Query: 318 ----ANKNIA-NPTATLLASCMMLDHLK-------LHSYATSIRKAVLASMDNENMHTPD 365 + + NP A++ A L+H L +A + K + ++++ M T D Sbjct: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAM-TKD 414 Query: 366 IGG-------------QGTTSEAIQDVIRHIRVINGR 389 + G T++ + + ++ GR Sbjct: 415 LAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451 >6BL1-B nrPDB Length = 425 Score = 68.1 bits (165), Expect = 6e-12, Method: Composition-based stats. Identities = 66/381 (17%), Positives = 125/381 (32%), Gaps = 64/381 (16%) Query: 48 SAKYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVS----SNADEEDIRNA 103 S K G V M GD + + +K V +D + +++ ++A Sbjct: 2 SKKISGGSVVEM-QGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA 60 Query: 104 IMAIRRNRVALKGNIETNH-------NLPPSHKSRNNILRTSLD--LYANVIHCKSLPGV 154 AI+++ V +K T L KS N +R L ++ I CK++P + Sbjct: 61 AEAIKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL 120 Query: 155 VTRHKDIDILIVRENTEGEYSS------------LEHESVAGVVESLKIITKAK------ 196 V+ I+I R +Y + + + G + ++ + Sbjct: 121 VSGWVK-PIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVA 179 Query: 197 ---------SLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY---- 243 A +F++A G + K I+K DG F +E+ + Sbjct: 180 MGMYNQDKSIEDFAHSSFQMALSKGWP-LYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQ 238 Query: 244 ---PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANY- 299 +I +E+ ++D+ Q + F + N G++ ++ A G G++ Sbjct: 239 FEAQKIWYEHRLIDDMVAQAMKSEGGF-IWACKNYDGDVQSDSVAQGYGSLGMMTSVLVC 297 Query: 300 GHVYAVFETATRNTGKSI-----ANKNIA-NPTATLLASCMMLDH---LKLHSYATSIRK 350 V A T + + NP A++ A L H L + Sbjct: 298 PDGKTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFAN 357 Query: 351 AVLAS---MDNENMHTPDIGG 368 A+ T D+ Sbjct: 358 ALEEVSIETIEAGFMTKDLAA 378 >4AOY-A nrPDB Length = 402 Score = 66.5 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 65/398 (16%), Positives = 133/398 (33%), Gaps = 74/398 (18%) Query: 54 RHTVTMIPGDGIGPELMLHVKSVFRHA----CVPVDFEEVHVS----SNADEEDIRNAIM 105 + V ++ DG E+ + + + + ++ E + +++ +A Sbjct: 5 KMKVPLVEMDG--DEMTRIIWRLIKENLLEPYIELNTEYYDLGLENRDKTEDQVTIDAAR 62 Query: 106 AIRRNRVALKGNIETNH-------NLPPSHKSRNNILRTSLD-------LYAN-VIHC-- 148 AI++ V +K T + NL KS N +R LD + N + Sbjct: 63 AIQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPIVVNSIKPFVK 122 Query: 149 -----------------KSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKI 191 K++ V +++ EN E ++ GV+ + Sbjct: 123 GWKKPISIARHAYGDVYKNVEYYVPSAGKAELVFTSENGEVSRQTIHEFDGPGVIMGMH- 181 Query: 192 ITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAA-RYPQ----- 245 T A F A + + + K I K D F +E+ Y + Sbjct: 182 NTDKSIRSFARACFNYALDMNQD-LWFSTKDTISKTYDHRFKDIFQEIYENEYKEKFEAK 240 Query: 246 -ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVY 303 + + ++D+ +++ V N G++++++ A G ++ Sbjct: 241 NLQYFYTLIDDAVARIIRSEGGM-VWACKNYDGDVMSDMVASAFGSLAMMTSVLVSPDGK 299 Query: 304 AVFETATRNTGKSIANKNI------ANPTATLLASCMMLDHLK-------LHSYATSIRK 350 FE A T K++ N AT+ A L L +AT + + Sbjct: 300 YEFEAA-HGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRGELDGIKELVDFATKLEQ 358 Query: 351 AVLASMDNENMHTPDIGGQGTTSEA----IQDVIRHIR 384 A + +++N + T D+ E +D ++ IR Sbjct: 359 ASVQTIEN-GVMTKDLASLSEVPEKKIVNTEDFLKEIR 395 >3US8-A nrPDB Length = 427 Score = 63.1 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 56/300 (18%), Positives = 105/300 (35%), Gaps = 49/300 (16%) Query: 60 IPGDGIGPELMLHVKSVFRHACVPVDFEEVHVS----SNADEEDIRNAIMAIRRNRVALK 115 + GD + + +K H + +D E + D++ +A AI+++ V +K Sbjct: 36 LDGDEMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTIDAANAIKKHGVGVK 95 Query: 116 GNIETNH-------NLPPSHKSRNNILRTSLD--LYANVIHCKSLPGVVTRHKDIDILIV 166 T L KS N +R L ++ I CK++P +V I++ Sbjct: 96 CATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRLVPGWTK-PIIVG 154 Query: 167 RENTEGEYSS----------------------LEHES--VAGVVESLKIITKAKS-LRIA 201 R +Y + +EH+ G +L + +S A Sbjct: 155 RHAFGDQYRATDFKFPGKGKLSIKFVGEDGQTIEHDVYDAPGAGVALAMYNLDESITEFA 214 Query: 202 EYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCC-----REVAARY--PQITFENMIVD 254 +F + V K I+K DG F E AA++ ++ +E+ ++D Sbjct: 215 RASFNYGLQRKVP-VYLSTKNTILKAYDGRFKDIFQKVFDEEFAAQFKAEKLWYEHRLID 273 Query: 255 NTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRNT 313 + + + V N G++ +++ A G GL+ V A T Sbjct: 274 DMVASALKWSGGY-VWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDGKTVEAEAAHGT 332 >4HCX-A nrPDB Length = 409 Score = 63.1 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 68/376 (18%), Positives = 125/376 (33%), Gaps = 79/376 (21%) Query: 60 IPGDGIGPELMLHVKSVFRHACVPVDFEEVHVS----SNADEEDIRNAIMAIRRNRVALK 115 + GD + + +K + + + + + D++ +A AI+++ V +K Sbjct: 16 LDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAYAIKKHGVGVK 75 Query: 116 GNIETNH-------NLPPSHKSRNNILRTSLD--------LYANVIHCKSLPGVVTRHKD 160 T NL S N +R L + +NV + +PG Sbjct: 76 CATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNV--PRLVPGWTKP--- 130 Query: 161 IDILIVRENTEGEYSS-----------------------LEHESVA-----GVVESLKII 192 I+I R +Y + + HE V+ GVV + Sbjct: 131 --IVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGMYNF 188 Query: 193 TKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARY-------PQ 245 K A +F + + V K I+K DG+F V Sbjct: 189 -KESIRDFARASFSYGL-NAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAG 246 Query: 246 ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANY-GHVYA 304 +T+E+ ++D+ + + V N G++ ++ A G GL+ Sbjct: 247 LTYEHRLIDDMVAACLKWEGGY-VWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 Query: 305 VFETATRNTGKSI-----ANKNIA-NPTATLLASCMMLDHLK-------LHSYATSIRKA 351 V A T A K + NP A++ A L H + +A + Sbjct: 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 Query: 352 VLASMDNENMHTPDIG 367 V+A++++ M T D+ Sbjct: 366 VIATVESGKM-TKDLA 380 >2UXQ-A nrPDB Length = 402 Score = 51.9 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 50/335 (14%), Positives = 108/335 (32%), Gaps = 62/335 (18%) Query: 89 VHVSSNADEEDIRNAIMAIRRNRVALKGNIETNHN-------LPPSHKSRNNILRTSLD- 140 + +++ +A AI++ V +K T + L KS N +R LD Sbjct: 45 IEERDRTNDQITIDAAEAIKKYGVGVKNATITPNQDRVEEYGLKEQWKSPNATVRAMLDG 104 Query: 141 -LYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLE--------------HESVAGV 185 ++ I K++ R I++ R Y + E ++ Sbjct: 105 TVFRKPIMVKNIK-PSVRSWQKPIVVGRHAYGDFYKNAEIFAEAGGKLEIVVTDKNGKET 163 Query: 186 VESLKIITKAKSLR-----------IAEYAFKLAQESGRKKVTA--VHKANIMKLGDGLF 232 +++ + + ++ A F+ + + +K+ K I K D F Sbjct: 164 RQTIMEVDEPAIVQGIHNTVASIGHFARACFEYSLD---QKIDCWFATKDTISKQYDQRF 220 Query: 233 LQCCREV-AARYPQ------ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCA 285 E+ A Y + I + ++D+ +++ + N G++++++ A Sbjct: 221 KIIFEEIFAQEYKEKFAAAGIEYFYTLIDDVVARMMKTEGGM-LWACKNYDGDVMSDMVA 279 Query: 286 GLVGGPGLVAGANYGHVYAVFE-TATRNTGKSIANKNI------ANPTATLLASCMMLDH 338 G +++ Y FE A T + +++ NP A + A L Sbjct: 280 SAFGSLAMMSSVLVS-PYGYFEYEAAHGTVQRHYYQHLKGERTSTNPVALIYAWTGALRK 338 Query: 339 LKLHS------YATSIRKAVLASMDNENMHTPDIG 367 +A+ T D+ Sbjct: 339 RGELDGTPDLCAFCDSLEAITIECIESGYMTGDLA 373 >4A8J-A nrPDB Length = 361 Score = 35.3 bits (80), Expect = 0.049, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 40/107 (37%), Gaps = 22/107 (20%) Query: 111 RVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENT 170 RV L +I + PP +LR D N+ + + L Sbjct: 259 RVVLFASISIDIITPP----LLVLLRNMFDSVINLEPFN--------QEMTEFL------ 300 Query: 171 EGEYSSLEHESVAGVVESLK--IITKAKSLRIAEYAFKLAQESGRKK 215 E Y S + G+V LK + T +R+ + + A ++GRKK Sbjct: 301 ERVYKSQPGKIQHGLVHILKLPVFTDRGEMRVLKS--EWAFKNGRKK 345 >5Z16-A nrPDB Length = 751 Score = 34.9 bits (79), Expect = 0.068, Method: Composition-based stats. Identities = 14/121 (11%), Positives = 42/121 (34%), Gaps = 18/121 (14%) Query: 269 VMVMPNLYGNIVNNVCAG--LVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIA--- 323 + V N+ + + ++ L +++ ++ET + + + Sbjct: 548 ISVTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEENH 607 Query: 324 ---NPTATLLASCMMLDHLKLHS-------YATSIRKAVLASMDNENM---HTPDIGGQG 370 + LA + L+ + + A ++ +A +DN+ T ++ +G Sbjct: 608 LRWDSLGEFLALAVSLEEMGIKENNARTKLLAKTLDEATGKLLDNDKSPSRRTGELDNRG 667 Query: 371 T 371 + Sbjct: 668 S 668 >4JQP-A nrPDB Length = 342 Score = 34.2 bits (77), Expect = 0.098, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 25/66 (37%), Gaps = 7/66 (10%) Query: 265 QQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETAT-RNTGKSIANKNIA 323 FD++V ++ G V GL AG N V T+ T IA K + Sbjct: 270 GDFDLVVAM------YHDQGHGPVKVLGLEAGVNVTVGLEVIRTSVDHGTAFDIAGKGVV 323 Query: 324 NPTATL 329 + + L Sbjct: 324 DEGSML 329 >1J1W-A nrPDB Length = 741 Score = 33.0 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 16/114 (14%), Positives = 37/114 (32%), Gaps = 15/114 (13%) Query: 269 VMVMPNLYGNIVNNVCAG--LVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIA--- 323 + V N+ + + ++ L +++ +FET + + + Sbjct: 539 ISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMSGGGLFETGAGGSAPKHVQQFLEEGY 598 Query: 324 ---NPTATLLASCMMLDHLK-------LHSYATSIRKAVLASMDNENMHTPDIG 367 + LA L+HL A+++ +A +DN +G Sbjct: 599 LRWDSLGEFLALAASLEHLGNAYKNPKALVLASTLDQATGKILDNNKSPARKVG 652 >2C07-A nrPDB Length = 285 Score = 31.1 bits (69), Expect = 0.81, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 54/120 (45%), Gaps = 13/120 (10%) Query: 274 NLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNI-ANPTAT-LLA 331 N YG I+N + +VG G V ANY A T++ K +A++NI N A ++ Sbjct: 170 NRYGRIIN--ISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPGFIS 227 Query: 332 SCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGT---TSEAIQDVIRHIRVING 388 S M + I+K +++++ M TP+ +S+ + + VI+G Sbjct: 228 SDM------TDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDG 281 >6G3U-A nrPDB Length = 737 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 5/50 (10%), Positives = 17/50 (34%), Gaps = 2/50 (4%) Query: 269 VMVMPNLYGNIVNNVCAG--LVGGPGLVAGANYGHVYAVFETATRNTGKS 316 + V N+ + + ++ L +++ ++ET + Sbjct: 535 ISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPK 584 >4ZDA-A nrPDB Length = 767 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/101 (11%), Positives = 32/101 (31%), Gaps = 17/101 (16%) Query: 269 VMVMPNLYGNIVNNVCAGLVGG-----PGLVAGANYGHVYAVFETATRNTGKSIANKNIA 323 + N+ + + ++ L G +V ++ET + ++ + Sbjct: 542 IAATGNILRDYLTDLFPILELGTSAKMLSIVP---LMAGGGLYETGAGGSAPKHVHQLVE 598 Query: 324 ------NPTATLLASCMMLDHLK---LHSYATSIRKAVLAS 355 + LA L+ + + A + KA+ + Sbjct: 599 ENHLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTA 639 >4U33-A nrPDB Length = 723 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 35/109 (32%), Gaps = 11/109 (10%) Query: 172 GEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGL 231 G Y E V E + ++ + F A + GR + + NI++ Sbjct: 554 GMYCGYELFEHRAVREGSEEYLDSEKYELRPRDFASALDQGRSLQPFITRLNIIRRLHPA 613 Query: 232 FLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD---VMVMPNLYG 277 F Q I F ++ D P D V+V N +G Sbjct: 614 FQQLRT--------IHFHHVDNDALLAYSKFDPATGDCVLVVVTLNAFG 654 >4ATY-A nrPDB Length = 349 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 50/157 (31%), Gaps = 30/157 (19%) Query: 183 AGVVESLKIITKAKSLRIAEYAFKLAQESGRKK-VTAVHKANIMKLGDGLF----LQCCR 237 G+ +L + + R A A + Q G V + N GLF + Sbjct: 188 EGIASALARLDQRHVERAARAAVQALQLMGIAHPVVGLMGINPHAGEGGLFGRDDIDITE 247 Query: 238 EVAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVA-- 295 VA + D T V PQ D+++ +I +V + G + Sbjct: 248 PVARKLRD--------DGMT---VIGPQGADLLLT---NPDI--DVFVAMYHDQGHIPVK 291 Query: 296 ------GANYGHVYA-VFETATRNTGKSIANKNIANP 325 A +F + +G IA +A+P Sbjct: 292 LRAGRHSAALSIGAGVLFSSVGHGSGFDIAGTLLADP 328 >5VAW-A nrPDB Length = 508 Score = 29.9 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 31/100 (31%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ A P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQAALYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >5KVU-A nrPDB Length = 745 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 4/50 (8%), Positives = 16/50 (32%), Gaps = 2/50 (4%) Query: 269 VMVMPNLYGNIVNNVCAGL--VGGPGLVAGANYGHVYAVFETATRNTGKS 316 + N+ + + ++ L +++ ++ET + Sbjct: 542 IAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPK 591 >5CFV-A nrPDB Length = 495 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 31/100 (31%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ A P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITP--DKAFQAALYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >1YE8-A nrPDB Length = 178 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 36/95 (37%), Gaps = 20/95 (21%) Query: 200 IAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIVDNTTMQ 259 I E A++ A++ R+KV + + M+L F R++ P + I Sbjct: 87 ILERAYREAKK-DRRKVIIIDEIGKMELFSKKFRDLVRQIMHD-PNVNVVATIPIRDVHP 144 Query: 260 LVSR-------------PQQFDVMVMPNLYGNIVN 281 LV P+ DV++ +I++ Sbjct: 145 LVKEIRRLPGAVLIELTPENRDVILE-----DILS 174 >1D5A-A nrPDB Length = 733 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 25/77 (32%), Gaps = 15/77 (19%) Query: 136 RTSLDLYANVIHCKSLPG--VVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIIT 193 R DLY + +LP + T ++ + E V + + Sbjct: 255 RIHFDLYPVIRRTINLPTYTLETVYEPV-------------FGQPAEKVYAEEIAEAWAS 301 Query: 194 KAKSLRIAEYAFKLAQE 210 R+A Y+ + A+ Sbjct: 302 GEGLERVARYSMEDAKA 318 >2B0T-A nrPDB Length = 738 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 15/114 (13%), Positives = 33/114 (28%), Gaps = 15/114 (13%) Query: 269 VMVMPNLYGNIVNNVCAGL--VGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIA--- 323 + V N+ + ++ L +++ +FET + + Sbjct: 535 ISVTGNVLRDYNTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQQVQEENH 594 Query: 324 ---NPTATLLASCMMLDH-------LKLHSYATSIRKAVLASMDNENMHTPDIG 367 + LA H K A ++ KA ++ E + +G Sbjct: 595 LRWDSLGEFLALAESFRHELNNNGNTKAGVLADALDKATEKLLNEEKSPSRKVG 648 >3ZYY-X nrPDB Length = 631 Score = 29.5 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 40/115 (34%), Gaps = 13/115 (11%) Query: 92 SSNADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSL 151 ++ AI + + LK +T +DL AN+ Sbjct: 407 GIKHGMRAMQGAIERVSISEAGLKVKYQT----VGGIPPVGICGSGLIDLLANLKRA--- 459 Query: 152 PGVVTRHKDIDILI----VRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAE 202 G++ R ID + +RE +G L + +G + + +IT+A + Sbjct: 460 -GIIDRSGKIDRTVNKERIREGEDGLEFVLAWANESGNNKDI-VITEADIQNLIR 512 >1F1E-A nrPDB Length = 154 Score = 29.2 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 175 SSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKV 216 + +E S V K+I + + + E A + A E GRK V Sbjct: 95 AGIERASSDAVDLYNKLICR-ATEELGEKAAEYADEDGRKTV 135 >2XIG-A nrPDB Length = 150 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 9/64 (14%), Positives = 23/64 (35%), Gaps = 1/64 (1%) Query: 187 ESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQI 246 E I+ ++ + +++A + + +H I++ D EV +Y Sbjct: 72 EKENFISVLETSKSGRR-YEIAAKEHHDHIICLHCGKIIEFADPEIENRQNEVVKKYQAK 130 Query: 247 TFEN 250 + Sbjct: 131 LISH 134 >3RUY-A nrPDB Length = 392 Score = 28.8 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 23/65 (35%), Gaps = 10/65 (15%) Query: 271 VMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLL 330 V P++Y I+ G G + A + VFE + + NP A + Sbjct: 242 VTPDMY--ILGKALGG--GVFPISCAAANRDILGVFEPGSHGSTFG------GNPLACAV 291 Query: 331 ASCMM 335 + + Sbjct: 292 SIAAL 296 >1CHM-A nrPDB Length = 401 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 27/75 (36%), Gaps = 11/75 (14%) Query: 239 VAARYPQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGAN 298 +AARYP ++ M+++ ++ ++ +I GG +V Sbjct: 135 LAARYPDAELVDVAAACMRMRMIKSAEEHVMIRHGARIADI---------GGAAVVEA-- 183 Query: 299 YGHVYAVFETATRNT 313 G +E A T Sbjct: 184 LGDQVPEYEVALHAT 198 >5T05-A nrPDB Length = 692 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >5HZV-A nrPDB Length = 626 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 48 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 105 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 106 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 145 >4WRN-A nrPDB Length = 695 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 53 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 110 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 111 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 150 >3PY7-A nrPDB Length = 523 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >2VWK-A nrPDB Length = 773 Score = 28.4 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 22/77 (28%), Gaps = 17/77 (22%) Query: 136 RTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEY---SSLEHESVAGVVESLKII 192 R DLY + +LP E Y E V + Sbjct: 255 RIHFDLYPVIRRTINLPTYTL--------------EAVYEAIFGQPKEKVYAEEIAQAWE 300 Query: 193 TKAKSLRIAEYAFKLAQ 209 T R+A Y+ + A+ Sbjct: 301 TGEGLERVARYSMEDAK 317 >5W0U-B nrPDB Length = 549 Score = 28.4 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >3OB4-A nrPDB Length = 500 Score = 28.4 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 44 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 101 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 102 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 141 >6EG3-A nrPDB Length = 621 Score = 28.4 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 44 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 101 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 102 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 141 >5BT8-A nrPDB Length = 403 Score = 28.4 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 53/115 (46%), Gaps = 12/115 (10%) Query: 280 VNNVCAGLVGGPGLV----AGANYGHVYAVFETATRNTGKSIANK-NIANPTATLLASCM 334 ++ +C L+ G G+ A A Y +++E T K IA K ++ PT ++A Sbjct: 212 LSGICDQLIVGGGIANTFLAAAGYNVGKSLYEADLVETAKQIAAKVSVPLPTDVVVADAS 271 Query: 335 ML---DHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTTSEAIQDVIRHIRVI 386 + D L + A ++ K V N+ + D+G + T++A +++ + I Sbjct: 272 QINFEDFLGSLAAAQAVIKKVEDVTANDMIL--DVGPE--TAKAFANILTTSKTI 322 >6MUU-A nrPDB Length = 791 Score = 28.4 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 30/80 (37%), Gaps = 10/80 (12%) Query: 165 IVRENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANI 224 + RE Y ++E E V+G + + + F A++ + K+T V K Sbjct: 335 LYREFESDLYLAIEWEPVSG-----REFGREGGKNL----FAEARKRLKHKLT-VRKLKR 384 Query: 225 MKLGDGLFLQCCREVAARYP 244 GLF E A P Sbjct: 385 FGEIKGLFEHGHTERLAECP 404 >3DM0-A nrPDB Length = 694 Score = 28.4 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 44 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 101 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 102 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 141 >5HZW-A nrPDB Length = 691 Score = 28.0 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 53 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 110 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 111 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 150 >5II5-A nrPDB Length = 496 Score = 28.0 bits (61), Expect = 6.8, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 48 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 105 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 106 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 145 >4K8X-A nrPDB Length = 775 Score = 28.0 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 22/77 (28%), Gaps = 17/77 (22%) Query: 136 RTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEY---SSLEHESVAGVVESLKII 192 R DLY + +LP E Y E V + Sbjct: 255 RIHFDLYPVIRRTINLPTYTL--------------EAVYEAVFGKPKEKVYAEEIAQAWE 300 Query: 193 TKAKSLRIAEYAFKLAQ 209 + R+A Y+ + A+ Sbjct: 301 SGEGLERVARYSMEDAK 317 >5IIC-A nrPDB Length = 496 Score = 28.0 bits (61), Expect = 7.1, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 48 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 105 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 106 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 145 >1MZB-A nrPDB Length = 136 Score = 28.0 bits (61), Expect = 7.7, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 33/92 (35%), Gaps = 9/92 (9%) Query: 171 EGEYSSL-EHESVAGVVESLKIITKAKSLRIA--------EYAFKLAQESGRKKVTAVHK 221 E Y +L E G+ +++T+ ++ + F+LA + V Sbjct: 38 EDVYKALMEAGEDVGLATVYRVLTQFEAAGLVVRHNFDGGHAVFELADSGHHDHMVCVDT 97 Query: 222 ANIMKLGDGLFLQCCREVAARYPQITFENMIV 253 +++ D + +E+ ++ +V Sbjct: 98 GEVIEFMDAEIEKRQKEIVRERGFELVDHNLV 129 >5HZ7-A nrPDB Length = 490 Score = 28.0 bits (61), Expect = 8.1, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >4IFP-A nrPDB Length = 466 Score = 28.0 bits (61), Expect = 8.2, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >6D67-A nrPDB Length = 520 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >4XZS-A nrPDB Length = 446 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >5Y2G-A nrPDB Length = 595 Score = 27.6 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >5JST-A nrPDB Length = 443 Score = 27.6 bits (60), Expect = 8.7, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >6DD2-A nrPDB Length = 449 Score = 27.6 bits (60), Expect = 8.8, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 16/38 (42%) Query: 145 VIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESV 182 V + P V + ++D++I R +T Y S Sbjct: 11 VRPAGATPQRVLWNSNVDLVIPRIHTASVYFYRPDPSG 48 >5WQ6-A nrPDB Length = 476 Score = 27.6 bits (60), Expect = 8.8, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >1O5O-A nrPDB Length = 221 Score = 27.6 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 25/75 (33%), Gaps = 10/75 (13%) Query: 174 YSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFL 233 Y+ L + V L + I A ++ +E+G KK+T V Sbjct: 127 YAKLPPLNDDKEVFLLDPMLATGVSSI--KAIEILKENGAKKITLV--------ALIAAP 176 Query: 234 QCCREVAARYPQITF 248 + V +Y + Sbjct: 177 EGVEAVEKKYEDVKI 191 >5GPQ-A nrPDB Length = 467 Score = 27.6 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >4XA2-A nrPDB Length = 498 Score = 27.6 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >3VD8-A nrPDB Length = 489 Score = 27.6 bits (60), Expect = 9.7, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 45 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 102 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 103 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 142 >5TJ4-A nrPDB Length = 561 Score = 27.6 bits (60), Expect = 9.9, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 30/100 (30%), Gaps = 10/100 (10%) Query: 42 EQTIPPSAKYGGRHTVTMIPGD--------GIGPELMLHVKSVFRHACVPVDFEEVHVSS 93 E+ P A G + D G+ E+ F+ P ++ V + Sbjct: 44 EEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPAA--AFQDKLYPFTWDAVRYNG 101 Query: 94 NADEEDIRNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133 I +++ N+ L +T +P K Sbjct: 102 KLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKA 141 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.144 0.414 Lambda K H 0.267 0.0444 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,949,617 Number of Sequences: 36641 Number of extensions: 711556 Number of successful extensions: 2342 Number of sequences better than 10.0: 110 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 65 Number of HSP's that attempted gapping in prelim test: 1914 Number of HSP's gapped (non-prelim): 175 length of query: 393 length of database: 10,336,785 effective HSP length: 99 effective length of query: 294 effective length of database: 6,709,326 effective search space: 1972541844 effective search space used: 1972541844 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.6 bits)