BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P50225 (295 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3U3O-A nrPDB 612 e-176 1CJM-A nrPDB 577 e-165 2ZVQ-X nrPDB 384 e-107 2Z5F-A nrPDB 349 8e-97 2GWH-A nrPDB 343 6e-95 3BFX-A nrPDB 328 1e-90 4JVN-A nrPDB 324 3e-89 2REO-A nrPDB 323 6e-89 1AQU-A nrPDB 318 2e-87 1Q22-A nrPDB 218 4e-57 1Q1Q-A nrPDB 216 8e-57 1OV4-A nrPDB 204 3e-53 1ZD1-A nrPDB 174 4e-44 5X2B-D nrPDB 171 3e-43 5MEK-A nrPDB 108 2e-24 1X8L-A nrPDB 108 2e-24 1Q44-A nrPDB 108 4e-24 3NIB-A nrPDB 57 1e-08 3MGC-A nrPDB 53 2e-07 4EEC-A nrPDB 45 3e-05 3HOX-E nrPDB 28 5.7 4N78-D nrPDB 27 8.6 >3U3O-A nrPDB Length = 315 Score = 612 bits (1579), Expect = e-176, Method: Compositional matrix adjust. Identities = 293/295 (99%), Positives = 294/295 (99%) Query: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 60 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM Sbjct: 21 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 80 Query: 61 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 120 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD Sbjct: 81 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 140 Query: 121 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 180 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW Sbjct: 141 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 200 Query: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY 240 ELSRTHPVLYLFYEDMKENPKREIQKILEFVG SLPEETVDF+VQHTSFKEMKKNPMTNY Sbjct: 201 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNY 260 Query: 241 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL Sbjct: 261 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 315 >1CJM-A nrPDB Length = 295 Score = 577 bits (1487), Expect = e-165, Method: Compositional matrix adjust. Identities = 274/295 (92%), Positives = 284/295 (96%) Query: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 60 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLI+TYPKSGTTWVSQILDM Sbjct: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDM 60 Query: 61 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 120 IYQGGDLEKC+RAPI++RVPFLE PG PSG+ETLKDTP PRL+K+HLPLALLPQTLLD Sbjct: 61 IYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLD 120 Query: 121 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 180 QKVKVVYVARN KDVAVSYYHF+ M K HPEPGTWDSFLEKFM GEVSYGSWYQHVQEWW Sbjct: 121 QKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWW 180 Query: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY 240 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEET+DF+VQHTSFKEMKKNPMTNY Sbjct: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNY 240 Query: 241 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 TTVPQE MDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL Sbjct: 241 TTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 >2ZVQ-X nrPDB Length = 295 Score = 384 bits (985), Expect = e-107, Method: Compositional matrix adjust. Identities = 173/290 (59%), Positives = 222/290 (76%) Query: 6 DTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGG 65 D R L V+G+PL AE ++SF+ARPDD+LISTYPKSGTTWVS+ILD+IY G Sbjct: 6 DVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVSEILDLIYNNG 65 Query: 66 DLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKV 125 D EKC R I+ RVPF+E PGI +G+E L + P+PR++KTHLP+ LLP + K+ Sbjct: 66 DAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWKNDCKI 125 Query: 126 VYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRT 185 +YVARNAKDV VSYY+FY MAK+HPEPGTW+ FLEKFM G+VS+G WY HV+ WWE + Sbjct: 126 IYVARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWWEKRKE 185 Query: 186 HPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQ 245 + +LYLFYEDMKENPK EIQKIL+F+ + +PEE ++ ++ H+SF MK+NP NYTT+ + Sbjct: 186 YRILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANYTTMMK 245 Query: 246 EFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 E MDHS+SPFMRKG++GDWK FTVAQ E+F+ DY +KM +L FRSE+ Sbjct: 246 EEMDHSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI 295 >2Z5F-A nrPDB Length = 298 Score = 349 bits (895), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 157/292 (53%), Positives = 213/292 (72%), Gaps = 1/292 (0%) Query: 5 QDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQG 64 +D R L+ V G P+ FA ++ F +RPDD++I+TYPKSGTTWVS+I+DMI Sbjct: 7 KDILRKDLKLVHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDMILND 66 Query: 65 GDLEKCHRAPIFMRVPFLEFKAPGI-PSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKV 123 GD+EKC R I +VP LE PG+ SG+E L+ P+PR++KTHLP LLP++ + Sbjct: 67 GDIEKCKRGFITEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNC 126 Query: 124 KVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELS 183 K++Y+ARNAKDV+VSYYHF M + P PGTW+ +LEKF+ G+V+YGSW+ HV+ WW+ Sbjct: 127 KMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKRK 186 Query: 184 RTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTV 243 HP+L+L+YEDMKENPK EI+KI+ F+ ++L +E +D ++ HTSF+ MK NP+ NYT + Sbjct: 187 EEHPILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHL 246 Query: 244 PQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 P MDHS SPFMRKG AGDWK FTVAQNE+FDA Y +M+ +L FR+E+ Sbjct: 247 PTTVMDHSKSPFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI 298 >2GWH-A nrPDB Length = 298 Score = 343 bits (879), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 157/285 (55%), Positives = 202/285 (70%) Query: 7 TSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGD 66 T R + YVKG+ + + +FQA+PDDLLISTYPK+GTTW +I+++I GD Sbjct: 10 TKRLSVNYVKGILQPTDTCDIWDKIWNFQAKPDDLLISTYPKAGTTWTQEIVELIQNEGD 69 Query: 67 LEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVV 126 +EK RAP R PFLE K P + SG+E P+PR+LKTHLP LLP +LL++ K++ Sbjct: 70 VEKSKRAPTHQRFPFLEMKIPSLGSGLEQAHAMPSPRILKTHLPFHLLPPSLLEKNCKII 129 Query: 127 YVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTH 186 YVARN KD VSYYHF M K P PGTW+ + E F+ G+V +GSW++HV+ WWE H Sbjct: 130 YVARNPKDNMVSYYHFQRMNKALPAPGTWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKH 189 Query: 187 PVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQE 246 +LYLFYEDMK+NPK EIQK+ EF+G+ L ++ +D +V +TSF MK+NPM NY+++P E Sbjct: 190 RILYLFYEDMKKNPKHEIQKLAEFIGKKLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAE 249 Query: 247 FMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSF 291 MDHSISPFMRKG GDWK FTVAQNERFD DY +KM L+F Sbjct: 250 IMDHSISPFMRKGAVGDWKKHFTVAQNERFDEDYKKKMTDTRLTF 294 >3BFX-A nrPDB Length = 296 Score = 328 bits (842), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 151/284 (53%), Positives = 201/284 (70%) Query: 12 LEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCH 71 L+ V+G L + +QSF+A+PDDLLI TYPK+GTTW+ +I+DMI Q GD+EKC Sbjct: 13 LKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQ 72 Query: 72 RAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARN 131 RA I R PF+E+ P PSG+E K P+PR+LKTHL LLP + + K +YVARN Sbjct: 73 RAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLYVARN 132 Query: 132 AKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYL 191 AKD VSYYHF M + P+PGTW+ + E F+ G+V +GSW+ HV+ WWE+ H +L+L Sbjct: 133 AKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQILFL 192 Query: 192 FYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHS 251 FYED+K +PK EI+K+++F+G+ + E +D +VQ TSF++MK+NPMTN +TV + +D S Sbjct: 193 FYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSILDQS 252 Query: 252 ISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 IS FMRKG GDWK FTVAQNERFD Y KM G S++F EL Sbjct: 253 ISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFSMEL 296 >4JVN-A nrPDB Length = 294 Score = 324 bits (831), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 146/284 (51%), Positives = 207/284 (72%) Query: 12 LEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCH 71 E V G+ + K F + +++FQARPDDL+I+TYPKSGTTWVS+I+ MIY+ GD+EKC Sbjct: 11 FEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCK 70 Query: 72 RAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARN 131 IF R+PFLE + + +G++ L + +PR++KTHLP LLP + ++ K++Y+ RN Sbjct: 71 EDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRN 130 Query: 132 AKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYL 191 AKDVAVS+Y+F+ M HP PG++ F+EKFM G+V YGSWY+HV+ WWE ++ VL+L Sbjct: 131 AKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFL 190 Query: 192 FYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHS 251 FYED+KE+ ++E+ K++ F+ R EE VD ++ HTSF+EMK NP TNYTT+P E M+ Sbjct: 191 FYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQK 250 Query: 252 ISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 +SPFMRKG+ GDWK FT A NE+FD Y ++M +L FR+E+ Sbjct: 251 LSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTEI 294 >2REO-A nrPDB Length = 305 Score = 323 bits (828), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 153/282 (54%), Positives = 200/282 (70%), Gaps = 1/282 (0%) Query: 15 VKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAP 74 V GVP + E + +FQA+PDDL+++TYPKSGTTW+ +ILDMI GD+EKC RA Sbjct: 24 VDGVPTLILSKEWWEKVANFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRAQ 83 Query: 75 IFMRVPFLEFKAPGIPS-GMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAK 133 R FLE K P +E + + +P+L+KTHLP L+P ++ + K+VYVARN K Sbjct: 84 TLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNPK 143 Query: 134 DVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFY 193 D VSYYHF+ MA P+P + F EKFM G+V GSW+ HV+ WW H +LYLFY Sbjct: 144 DCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLFY 203 Query: 194 EDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSIS 253 ED+K++PKREI+KIL+F+ + + EE ++ ++ HTSF MK+NPMTNYTT+P MDHSIS Sbjct: 204 EDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSIS 263 Query: 254 PFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 PFMRKGM GDWK FTVAQNE FD DY +KMAG +L+FR+E+ Sbjct: 264 PFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI 305 >1AQU-A nrPDB Length = 297 Score = 318 bits (814), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 143/280 (51%), Positives = 201/280 (71%) Query: 16 KGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 75 +GV + K F + ++ F ARPDDL+I+TYPKSGTTW+S+++ MIY+ GD+EKC I Sbjct: 18 RGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGDVEKCKEDAI 77 Query: 76 FMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDV 135 F R+P+LE + + +G++ LK+ +PR++KTHLP LLP + ++ K++Y+ RNAKDV Sbjct: 78 FNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMIYLCRNAKDV 137 Query: 136 AVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 195 AVSYY+F M +P P ++ F+EKFM G+V YGSWY HV+ WWE S+ VL++FYED Sbjct: 138 AVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSRVLFMFYED 197 Query: 196 MKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPF 255 MKE+ +RE+ K++EF+ R E VD ++QHTSF+EMK NP TNYT +P+E M+ +SPF Sbjct: 198 MKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMMNQKVSPF 257 Query: 256 MRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 MRKG+ GDWK F A ERFD Y ++M C++ FR EL Sbjct: 258 MRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKFRMEL 297 >1Q22-A nrPDB Length = 299 Score = 218 bits (554), Expect = 4e-57, Method: Compositional matrix adjust. Identities = 111/290 (38%), Positives = 172/290 (59%), Gaps = 10/290 (3%) Query: 2 ELIQDTSRPPLEYV--KGVP--LIKYFAEALGPLQSFQ-ARPDDLLISTYPKSGTTWVSQ 56 ++ + + + P EY KGVP + Y E++ ++ Q R DD+ I TYPKSGTTW+ + Sbjct: 6 DISEISQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIE 65 Query: 57 ILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQ 116 I+ +I + GD PI+ R P+ E G +L D +PRL+ +HLP+ + + Sbjct: 66 IICLILKEGDPSWIRSVPIWERAPWCETIV-----GAFSLPDQYSPRLMSSHLPIQIFTK 120 Query: 117 TLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHV 176 K KV+Y+ RN +DV VS YH+ +A +PGT D FL F+ GEV +GSW+ H+ Sbjct: 121 AFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHI 180 Query: 177 QEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNP 236 + W + L++ YE+++++ + +++I F+GR L +E + VV H++F MK N Sbjct: 181 KGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANT 240 Query: 237 MTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAG 286 M+NYT +P +DH F+RKG+ GDWK FTVAQ+E FD Y ++M G Sbjct: 241 MSNYTLLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRG 290 >1Q1Q-A nrPDB Length = 350 Score = 216 bits (551), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 111/281 (39%), Positives = 167/281 (59%), Gaps = 10/281 (3%) Query: 11 PLEYV--KGVP--LIKYFAEALGPLQSFQ-ARPDDLLISTYPKSGTTWVSQILDMIYQGG 65 P EY KGVP + Y E++ ++ Q R DD+ I TYPKSGTTW+ +I+ +I + G Sbjct: 13 PGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLILKEG 72 Query: 66 DLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKV 125 D PI+ R P+ E G +L D +PRL+ +HLP+ + + K KV Sbjct: 73 DPSWIRSVPIWERAPWCETIV-----GAFSLPDQYSPRLMSSHLPIQIFTKAFFSSKAKV 127 Query: 126 VYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRT 185 +Y+ RN +DV VS YH+ +A +PGT D FL F+ GEV +GSW+ H++ W + Sbjct: 128 IYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLRMKGK 187 Query: 186 HPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQ 245 L++ YE+++++ + +++I F+GR L +E + VV H++F MK N M+NYT +P Sbjct: 188 DNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYTLLPP 247 Query: 246 EFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAG 286 +DH F+RKG+ GDWK FTVAQ+E FD Y ++M G Sbjct: 248 SLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRG 288 >1OV4-A nrPDB Length = 293 Score = 204 bits (519), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 100/270 (37%), Positives = 165/270 (61%), Gaps = 7/270 (2%) Query: 17 GVPLIKYFAEALGPLQS-FQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 75 P + + +E L ++ F R +D++I TYPKSGT W+++IL +++ GD + PI Sbjct: 20 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 79 Query: 76 FMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDV 135 + R P++E + G L +T +PRL +HLP+ L P++ K KV+Y+ RN +DV Sbjct: 80 WERSPWVESEI-----GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 134 Query: 136 AVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 195 VS Y F+ K +P +W+ + E F G V YGSW+ H+ W + L L YE+ Sbjct: 135 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 194 Query: 196 MKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPF 255 +K++ R I+KI +F+G++L E ++ +++++SF+ MK+N M+NY+ + +++ + Sbjct: 195 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-TQL 253 Query: 256 MRKGMAGDWKTTFTVAQNERFDADYAEKMA 285 +RKG++GDWK FTVAQ E FD + EKMA Sbjct: 254 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMA 283 >1ZD1-A nrPDB Length = 284 Score = 174 bits (441), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 93/275 (33%), Positives = 150/275 (54%), Gaps = 18/275 (6%) Query: 17 GVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF 76 GV L + + + +F RP D+ I TYPKSGT+ + +++ ++ QG D ++ I Sbjct: 24 GVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLMNID 83 Query: 77 MRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVA 136 ++P LE+ PG ++ +K+ +PRL+K+HLP LP L + KV+Y+ARN KD+ Sbjct: 84 EQLPVLEYPQPG----LDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPKDLV 139 Query: 137 VSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDM 196 VSYY F+ + GT+ F +FM ++ YGSW++HVQE+WE VL+L YEDM Sbjct: 140 VSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKYEDM 199 Query: 197 KENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFM 256 + ++++ F+G S + ++ + +H + N +P + Sbjct: 200 HRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALP-----------V 245 Query: 257 RKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSF 291 +G G WK FTV+ NE+FD Y +KM C L+F Sbjct: 246 GRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 >5X2B-D nrPDB Length = 281 Score = 171 bits (433), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 97/262 (37%), Positives = 138/262 (52%), Gaps = 17/262 (6%) Query: 26 EALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFK 85 E LG L SF AR DD+ + +YPKSGT W++++++ I G I + P Sbjct: 18 ELLGSLDSFDAREDDIFLVSYPKSGTHWLAEVIERIPDAG---------ITLTSPI---- 64 Query: 86 APGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHM 145 G S E LK P R + THL +LP T+ ++ K++Y+ RN KD AVS +H+Y Sbjct: 65 ELGDISKFEELKRIPKRRAIPTHLNYEMLPVTVKQKQCKIIYIVRNPKDTAVSMFHYYRD 124 Query: 146 AKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQ 205 P TW +FLE F+ G+V YGSW+ HV W E VL++FYE+MK++ + ++ Sbjct: 125 NPNLPSTETWAAFLELFLKGDVVYGSWFDHVLSWEEHKNDKNVLFIFYEEMKKDFVKSLK 184 Query: 206 KILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISP---FMRKGMAG 262 KI F+G + + + + + TSF EMK N P + S RKG+ G Sbjct: 185 KITAFLGIDVNDSEMAKIARSTSFSEMKSNAAKE-NCDPNHVICALTSDRNLVFRKGVVG 243 Query: 263 DWKTTFTVAQNERFDADYAEKM 284 DW FT QN FD + EKM Sbjct: 244 DWINYFTPKQNRGFDELFTEKM 265 >5MEK-A nrPDB Length = 322 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 79/270 (29%), Positives = 120/270 (44%), Gaps = 17/270 (6%) Query: 34 FQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMR-----VPFLEFKAPG 88 FQARP D L+ +YPK+GTTW+ + I + P+ R VP++E P Sbjct: 54 FQARPSDFLVCSYPKTGTTWLKALTFAIANRSRFDDSSN-PLLKRNPHEFVPYIEIDFPF 112 Query: 89 IPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKV 148 P ++ LKD L TH+P LLP +++ K+VY+ R KD +S + F H + Sbjct: 113 FPE-VDVLKDK-GNTLFSTHIPYELLPDSVVKSGCKMVYIWREPKDTFISMWTFLHKERT 170 Query: 149 HPEP-GTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHP--VLYLFYEDMKENPKREIQ 205 P + + F G YG + H+ +W+ + +P +L+L YE M+ +P ++ Sbjct: 171 ELGPVSNLEESFDMFCRGLSGYGPYLNHILAYWKAYQENPDRILFLKYETMRADPLPYVK 230 Query: 206 KILEFVGRSLPEETVDFVVQHTSFK----EMKKNPMTNYTTVPQEFMD--HSISPFMRKG 259 + EF+G E + V E KN N +E ++ S + RKG Sbjct: 231 SLAEFMGHGFTAEEEEKGVVEKVVNLCSFETLKNLEANKGEKDREDRPGVYANSAYFRKG 290 Query: 260 MAGDWKTTFTVAQNERFDADYAEKMAGCSL 289 GDW T R D EK G L Sbjct: 291 KVGDWSNYLTPEMAARIDGLMEEKFKGTGL 320 >1X8L-A nrPDB Length = 351 Score = 108 bits (270), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 76/285 (26%), Positives = 133/285 (46%), Gaps = 34/285 (11%) Query: 16 KGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 75 KG + + + + + + RP D+ +++Y +SGTT +++ +I + E + + Sbjct: 41 KGYMVYRPYLKDAANIYNMPLRPTDVFVASYQRSGTTMTQELVWLIENDLNFEAA-KTYM 99 Query: 76 FMRVPFLEFKAPGIPSGMETLKDT-PAP-------------------------------R 103 +R +L+ P E D P P R Sbjct: 100 SLRYIYLDGFMIYDPEKQEEYNDILPNPENLDMERYLGLLEYSSRPGSSLLAAVPPTEKR 159 Query: 104 LLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFM 163 +KTHLPL+L+P +LD VK+VY+AR+ +DVAVS +H + + + + F E F Sbjct: 160 FVKTHLPLSLMPPNMLDT-VKMVYLARDPRDVAVSSFHHARLLYLLNKQSNFKDFWEMFH 218 Query: 164 VGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFV 223 G + +++HV+E W +L+LFYED ++ I +I +F+G+ L EE + + Sbjct: 219 RGLYTLTPYFEHVKEAWAKRHDPNMLFLFYEDYLKDLPGSIARIADFLGKKLSEEQIQRL 278 Query: 224 VQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTF 268 +H +F++ K N N + + F+RKG AG W+ F Sbjct: 279 SEHLNFEKFKNNGAVNMEDYREIGILADGEHFIRKGKAGCWRDYF 323 >1Q44-A nrPDB Length = 326 Score = 108 bits (269), Expect = 4e-24, Method: Compositional matrix adjust. Identities = 80/284 (28%), Positives = 133/284 (46%), Gaps = 38/284 (13%) Query: 32 QSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI-------------FMR 78 + F+A+ D+++ T PKSGTTW+ ++ + H+ P+ + Sbjct: 59 KRFEAKDSDIILVTNPKSGTTWLKALVFALLNR------HKFPVSSSGNHPLLVTNPHLL 112 Query: 79 VPFLE---FKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDV 135 VPFLE +++P P+PRL+ TH+ LP+++ K+VY RN KD+ Sbjct: 113 VPFLEGVYYESPDF-----DFSSLPSPRLMNTHISHLSLPESVKSSSCKIVYCCRNPKDM 167 Query: 136 AVSYYHFYHMAKVHPEPGT---WDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHP--VLY 190 VS +HF K+ PE + +E F G+ G ++ H+ E+W SR +P VL+ Sbjct: 168 FVSLWHF--GKKLAPEETADYPIEKAVEAFCEGKFIGGPFWDHILEYWYASRENPNKVLF 225 Query: 191 LFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQH-TSFKEMKKNPMTNYTTVPQEFMD 249 + YE++K+ + E+++I EF+ EE + SF+ + + +P Sbjct: 226 VTYEELKKQTEVEMKRIAEFLECGFIEEEEVREIVKLCSFESLSNLEVNKEGKLPNGIET 285 Query: 250 HSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 293 + F RKG G W+ T + + E D EK G L F S Sbjct: 286 KT---FFRKGEIGGWRDTLSESLAEEIDRTIEEKFKGSGLKFSS 326 >3NIB-A nrPDB Length = 309 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 64/241 (26%), Positives = 103/241 (42%), Gaps = 37/241 (15%) Query: 18 VPLIKYFAEALGPLQSFQARPDDLL-ISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF 76 VP + A G Q + + + I++YPK+G TW+ +L G K + Sbjct: 15 VPRGSHMASMTGGQQMGRGSMNGIRWIASYPKAGNTWLRCMLAAYITG----KAPQTWKD 70 Query: 77 MRVPFLEFKAPGIPSGMETLKDTP-----APRLLKTHLPLALLPQTLL--DQKVKVVYVA 129 M LE + GM L D P P L+KTHL A +P L + KV+Y+ Sbjct: 71 METVSLELE------GMLHLGDMPPTEPTKPVLVKTHLK-ADVPVLGLYSEATAKVLYLV 123 Query: 130 RNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYG----------SWYQHVQEW 179 RN +D+ +S +++ E +F F+ E SW ++V+ W Sbjct: 124 RNPRDILLSAMRMTAISRDDMESSR--TFARDFIANEGLRMRGRGGGAGLGSWPENVRIW 181 Query: 180 WELSRTH----PVLYLFYEDMKENPKREIQKILEF--VGRSLPEETVDFVVQHTSFKEMK 233 E SR VL + YED+K +P +I+EF +G + E + V + + M+ Sbjct: 182 TESSRDRFPNADVLTMRYEDLKGDPVARFSEIVEFLDLGDPVDIEDIRRAVAACTLERMR 241 Query: 234 K 234 + Sbjct: 242 E 242 >3MGC-A nrPDB Length = 319 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 76/308 (24%), Positives = 122/308 (39%), Gaps = 53/308 (17%) Query: 18 VPLIKYFAEALGPLQSFQARPDDLL-ISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF 76 VP + A G Q + + + I++YPK+G TWV +L G K + Sbjct: 15 VPRGSHMASMTGGQQMGRGSMNGIRWIASYPKAGNTWVRCMLAAYITG----KAPQVWND 70 Query: 77 MRVPFLEFKAPGIPSGMETLKDTP-----APRLLKTHLPLALLPQTLL--DQKVKVVYVA 129 + L +A M D P P L+KTHL A +P L + KV+Y+ Sbjct: 71 IDAESLTLEA------MLRFGDLPPAEPMEPVLVKTHLK-ADVPVLGLYGEATAKVLYLV 123 Query: 130 RNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGE------------VSYGSWYQHVQ 177 RN +D+ +S +++ E F KF+ E V GSW ++V+ Sbjct: 124 RNPRDMLLSSMRMASISRDDVEKSR--DFARKFIANEGLGWNALGAGGGVGLGSWPENVR 181 Query: 178 EWWELSRTH----PVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDF--VVQHTSFKE 231 W E S VL + YED+K +P +I+EF+ P + D V ++ + Sbjct: 182 SWTESSSDRFPNADVLTMRYEDLKGDPVARFSEIVEFLDLGGPVDIEDIRRAVAASTLER 241 Query: 232 MKKNPMTNYTTVPQEFMDHSISPFMRKGMAG-----------DWKTTFTVAQNERFDADY 280 M++ + + H + M+ G G D +F E ++DY Sbjct: 242 MRELEKRSEQQGGGSPIRHGDARMMKGGPGGARPQFVGEGRYDQSLSFL---GEDIESDY 298 Query: 281 AEKMAGCS 288 E + G S Sbjct: 299 QELLHGDS 306 >4EEC-A nrPDB Length = 286 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 58/245 (23%), Positives = 100/245 (40%), Gaps = 47/245 (19%) Query: 43 ISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGM----ETLKD 98 I++YPK+G W+ +L G +E PGI +G+ L+D Sbjct: 23 IASYPKAGGHWLRCMLTSYVTGEPVETW----------------PGIQAGVPHLEGLLRD 66 Query: 99 TPAPR-------LLKTHLPLAL-LPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHP 150 AP LL TH + + + KVV + RN +D +S M + P Sbjct: 67 GEAPSADPDEQVLLATHFTADRPVLRFYRESTAKVVCLIRNPRDAMLS---LMRMKGIPP 123 Query: 151 EP-GTWDSFLEKFMVGE--------VSYGSWYQHVQEWWE-LSRTHP---VLYLFYEDMK 197 E E F+ E GSW ++++ W + + + P VL + YED++ Sbjct: 124 EDVEACRKIAETFIADEGFSSVRIWAGEGSWPENIRSWTDSVHESFPNAAVLAVRYEDLR 183 Query: 198 ENPKREIQKILEFVGRSLPEETVDFVVQHT--SFKEM-KKNPMTNYTTVPQEFMDHSISP 254 ++P+ E+ K+++F+ + D V T +EM +++ + T P Sbjct: 184 KDPEGELWKVVDFLELGGRDGVADAVANCTLERMREMEERSKLLGLETTGLMTRGGKQLP 243 Query: 255 FMRKG 259 F+ KG Sbjct: 244 FVGKG 248 >3HOX-E nrPDB Length = 215 Score = 27.7 bits (60), Expect = 5.7, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 9/56 (16%) Query: 3 LIQDTSRPPLEYVKGVPLIKYFAEALG----PLQSFQARPDDLLISTYPKSGTTWV 54 + Q+ PLE K + +++G + SFQA P + IS +P G+ WV Sbjct: 30 ITQEEVELPLEDFKA-----KYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWV 80 >4N78-D nrPDB Length = 559 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 5/50 (10%) Query: 201 KREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDH 250 +RE QK+ + G L E+ + + +H E+ P +++ T PQ ++DH Sbjct: 201 RREWQKLAQ--GPELAEDDANLLHKHI---EVANGPASHFETRPQTYVDH 245 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3U3O-A nrPDB 469 e-133 1CJM-A nrPDB 463 e-131 2ZVQ-X nrPDB 423 e-119 2Z5F-A nrPDB 421 e-118 2GWH-A nrPDB 421 e-118 3BFX-A nrPDB 418 e-117 2REO-A nrPDB 407 e-114 4JVN-A nrPDB 406 e-114 1AQU-A nrPDB 395 e-110 1Q22-A nrPDB 351 2e-97 1Q1Q-A nrPDB 343 6e-95 1OV4-A nrPDB 320 6e-88 1ZD1-A nrPDB 316 5e-87 5X2B-D nrPDB 297 3e-81 1X8L-A nrPDB 273 6e-74 5MEK-A nrPDB 256 8e-69 1Q44-A nrPDB 248 2e-66 3MGC-A nrPDB 219 1e-57 3NIB-A nrPDB 210 6e-55 4EEC-A nrPDB 179 9e-46 Sequences not found previously or not previously below threshold: 4GBM-A nrPDB 55 2e-08 1T8T-A nrPDB 44 7e-05 4GOX-A nrPDB 43 1e-04 3RNL-A nrPDB 41 6e-04 1NST-A nrPDB 37 0.015 1ZRH-A nrPDB 35 0.028 3F5F-A nrPDB 35 0.058 4ETN-A nrPDB 33 0.17 3L7R-A nrPDB 31 0.51 3L86-A nrPDB 31 0.66 3AP1-A nrPDB 31 0.69 4EGS-A nrPDB 30 0.95 1WDE-A nrPDB 30 1.1 1X3Z-A nrPDB 30 1.2 1WZ2-A nrPDB 30 1.4 6AGH-A nrPDB 30 1.7 5IKB-A nrPDB 30 1.8 4WHN-A nrPDB 30 1.8 6EAZ-A nrPDB 28 3.6 5Y81-H nrPDB 28 3.7 3LBE-A nrPDB 28 3.7 2IHB-B nrPDB 28 3.8 2I59-A nrPDB 28 3.9 4NV8-A nrPDB 28 4.3 4M46-A nrPDB 28 4.7 5MMJ-p nrPDB 28 6.0 5UBJ-A nrPDB 27 9.4 >3U3O-A nrPDB Length = 315 Score = 469 bits (1208), Expect = e-133, Method: Composition-based stats. Identities = 293/295 (99%), Positives = 294/295 (99%) Query: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 60 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM Sbjct: 21 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 80 Query: 61 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 120 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD Sbjct: 81 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 140 Query: 121 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 180 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW Sbjct: 141 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 200 Query: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY 240 ELSRTHPVLYLFYEDMKENPKREIQKILEFVG SLPEETVDF+VQHTSFKEMKKNPMTNY Sbjct: 201 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGHSLPEETVDFMVQHTSFKEMKKNPMTNY 260 Query: 241 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL Sbjct: 261 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 315 >1CJM-A nrPDB Length = 295 Score = 463 bits (1191), Expect = e-131, Method: Composition-based stats. Identities = 274/295 (92%), Positives = 284/295 (96%) Query: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 60 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLI+TYPKSGTTWVSQILDM Sbjct: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDM 60 Query: 61 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 120 IYQGGDLEKC+RAPI++RVPFLE PG PSG+ETLKDTP PRL+K+HLPLALLPQTLLD Sbjct: 61 IYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLD 120 Query: 121 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 180 QKVKVVYVARN KDVAVSYYHF+ M K HPEPGTWDSFLEKFM GEVSYGSWYQHVQEWW Sbjct: 121 QKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWW 180 Query: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY 240 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEET+DF+VQHTSFKEMKKNPMTNY Sbjct: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNY 240 Query: 241 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 TTVPQE MDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL Sbjct: 241 TTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 >2ZVQ-X nrPDB Length = 295 Score = 423 bits (1087), Expect = e-119, Method: Composition-based stats. Identities = 174/295 (58%), Positives = 224/295 (75%) Query: 1 MELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDM 60 M+ D R L V+G+PL AE ++SF+ARPDD+LISTYPKSGTTWVS+ILD+ Sbjct: 1 MDNKLDVFRRELVDVEGIPLFWSIAEHWSQVESFEARPDDILISTYPKSGTTWVSEILDL 60 Query: 61 IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLD 120 IY GD EKC R I+ RVPF+E PGI +G+E L + P+PR++KTHLP+ LLP + Sbjct: 61 IYNNGDAEKCKRDAIYKRVPFMELIIPGITNGVEMLNNMPSPRIVKTHLPVQLLPSSFWK 120 Query: 121 QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWW 180 K++YVARNAKDV VSYY+FY MAK+HPEPGTW+ FLEKFM G+VS+G WY HV+ WW Sbjct: 121 NDCKIIYVARNAKDVVVSYYYFYQMAKIHPEPGTWEEFLEKFMAGQVSFGPWYDHVKSWW 180 Query: 181 ELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNY 240 E + + +LYLFYEDMKENPK EIQKIL+F+ + +PEE ++ ++ H+SF MK+NP NY Sbjct: 181 EKRKEYRILYLFYEDMKENPKCEIQKILKFLEKDIPEEILNKILYHSSFSVMKENPSANY 240 Query: 241 TTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 TT+ +E MDHS+SPFMRKG++GDWK FTVAQ E+F+ DY +KM +L FRSE+ Sbjct: 241 TTMMKEEMDHSVSPFMRKGISGDWKNQFTVAQYEKFEEDYVKKMEDSTLKFRSEI 295 >2Z5F-A nrPDB Length = 298 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 157/292 (53%), Positives = 213/292 (72%), Gaps = 1/292 (0%) Query: 5 QDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQG 64 +D R L+ V G P+ FA ++ F +RPDD++I+TYPKSGTTWVS+I+DMI Sbjct: 7 KDILRKDLKLVHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDMILND 66 Query: 65 GDLEKCHRAPIFMRVPFLEFKAPGI-PSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKV 123 GD+EKC R I +VP LE PG+ SG+E L+ P+PR++KTHLP LLP++ + Sbjct: 67 GDIEKCKRGFITEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNC 126 Query: 124 KVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELS 183 K++Y+ARNAKDV+VSYYHF M + P PGTW+ +LEKF+ G+V+YGSW+ HV+ WW+ Sbjct: 127 KMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKRK 186 Query: 184 RTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTV 243 HP+L+L+YEDMKENPK EI+KI+ F+ ++L +E +D ++ HTSF+ MK NP+ NYT + Sbjct: 187 EEHPILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHL 246 Query: 244 PQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 P MDHS SPFMRKG AGDWK FTVAQNE+FDA Y +M+ +L FR+E+ Sbjct: 247 PTTVMDHSKSPFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI 298 >2GWH-A nrPDB Length = 298 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 157/285 (55%), Positives = 202/285 (70%) Query: 7 TSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGD 66 T R + YVKG+ + + +FQA+PDDLLISTYPK+GTTW +I+++I GD Sbjct: 10 TKRLSVNYVKGILQPTDTCDIWDKIWNFQAKPDDLLISTYPKAGTTWTQEIVELIQNEGD 69 Query: 67 LEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVV 126 +EK RAP R PFLE K P + SG+E P+PR+LKTHLP LLP +LL++ K++ Sbjct: 70 VEKSKRAPTHQRFPFLEMKIPSLGSGLEQAHAMPSPRILKTHLPFHLLPPSLLEKNCKII 129 Query: 127 YVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTH 186 YVARN KD VSYYHF M K P PGTW+ + E F+ G+V +GSW++HV+ WWE H Sbjct: 130 YVARNPKDNMVSYYHFQRMNKALPAPGTWEEYFETFLAGKVCWGSWHEHVKGWWEAKDKH 189 Query: 187 PVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQE 246 +LYLFYEDMK+NPK EIQK+ EF+G+ L ++ +D +V +TSF MK+NPM NY+++P E Sbjct: 190 RILYLFYEDMKKNPKHEIQKLAEFIGKKLDDKVLDKIVHYTSFDVMKQNPMANYSSIPAE 249 Query: 247 FMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSF 291 MDHSISPFMRKG GDWK FTVAQNERFD DY +KM L+F Sbjct: 250 IMDHSISPFMRKGAVGDWKKHFTVAQNERFDEDYKKKMTDTRLTF 294 >3BFX-A nrPDB Length = 296 Score = 418 bits (1075), Expect = e-117, Method: Composition-based stats. Identities = 151/288 (52%), Positives = 202/288 (70%) Query: 8 SRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDL 67 + L+ V+G L + +QSF+A+PDDLLI TYPK+GTTW+ +I+DMI Q GD+ Sbjct: 9 KQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDV 68 Query: 68 EKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVY 127 EKC RA I R PF+E+ P PSG+E K P+PR+LKTHL LLP + + K +Y Sbjct: 69 EKCQRAIIQHRHPFIEWARPPQPSGVEKAKAMPSPRILKTHLSTQLLPPSFWENNCKFLY 128 Query: 128 VARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHP 187 VARNAKD VSYYHF M + P+PGTW+ + E F+ G+V +GSW+ HV+ WWE+ H Sbjct: 129 VARNAKDCMVSYYHFQRMNHMLPDPGTWEEYFETFINGKVVWGSWFDHVKGWWEMKDRHQ 188 Query: 188 VLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEF 247 +L+LFYED+K +PK EI+K+++F+G+ + E +D +VQ TSF++MK+NPMTN +TV + Sbjct: 189 ILFLFYEDIKRDPKHEIRKVMQFMGKKVDETVLDKIVQETSFEKMKENPMTNRSTVSKSI 248 Query: 248 MDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 +D SIS FMRKG GDWK FTVAQNERFD Y KM G S++F EL Sbjct: 249 LDQSISSFMRKGTVGDWKNHFTVAQNERFDEIYRRKMEGTSINFSMEL 296 >2REO-A nrPDB Length = 305 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 153/283 (54%), Positives = 200/283 (70%), Gaps = 1/283 (0%) Query: 14 YVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRA 73 V GVP + E + +FQA+PDDL+++TYPKSGTTW+ +ILDMI GD+EKC RA Sbjct: 23 EVDGVPTLILSKEWWEKVANFQAKPDDLILATYPKSGTTWMHEILDMILNDGDVEKCKRA 82 Query: 74 PIFMRVPFLEFKAPGIPS-GMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNA 132 R FLE K P +E + + +P+L+KTHLP L+P ++ + K+VYVARN Sbjct: 83 QTLDRHAFLELKFPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPPSIWKENCKIVYVARNP 142 Query: 133 KDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLF 192 KD VSYYHF+ MA P+P + F EKFM G+V GSW+ HV+ WW H +LYLF Sbjct: 143 KDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGKVVGGSWFDHVKGWWAAKDMHRILYLF 202 Query: 193 YEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSI 252 YED+K++PKREI+KIL+F+ + + EE ++ ++ HTSF MK+NPMTNYTT+P MDHSI Sbjct: 203 YEDIKKDPKREIEKILKFLEKDISEEILNKIIYHTSFDVMKQNPMTNYTTLPTSIMDHSI 262 Query: 253 SPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 SPFMRKGM GDWK FTVAQNE FD DY +KMAG +L+FR+E+ Sbjct: 263 SPFMRKGMPGDWKNYFTVAQNEEFDKDYQKKMAGSTLTFRTEI 305 >4JVN-A nrPDB Length = 294 Score = 406 bits (1043), Expect = e-114, Method: Composition-based stats. Identities = 146/284 (51%), Positives = 207/284 (72%) Query: 12 LEYVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCH 71 E V G+ + K F + +++FQARPDDL+I+TYPKSGTTWVS+I+ MIY+ GD+EKC Sbjct: 11 FEEVHGILMYKDFVKYWDNVEAFQARPDDLVIATYPKSGTTWVSEIVYMIYKEGDVEKCK 70 Query: 72 RAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARN 131 IF R+PFLE + + +G++ L + +PR++KTHLP LLP + ++ K++Y+ RN Sbjct: 71 EDVIFNRIPFLECRKENLMNGVKQLDEMNSPRIVKTHLPPELLPASFWEKDCKIIYLCRN 130 Query: 132 AKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYL 191 AKDVAVS+Y+F+ M HP PG++ F+EKFM G+V YGSWY+HV+ WWE ++ VL+L Sbjct: 131 AKDVAVSFYYFFLMVAGHPNPGSFPEFVEKFMQGQVPYGSWYKHVKSWWEKGKSPRVLFL 190 Query: 192 FYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHS 251 FYED+KE+ ++E+ K++ F+ R EE VD ++ HTSF+EMK NP TNYTT+P E M+ Sbjct: 191 FYEDLKEDIRKEVIKLIHFLERKPSEELVDRIIHHTSFQEMKNNPSTNYTTLPDEIMNQK 250 Query: 252 ISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 +SPFMRKG+ GDWK FT A NE+FD Y ++M +L FR+E+ Sbjct: 251 LSPFMRKGITGDWKNHFTEALNEKFDKHYEQQMKESTLKFRTEI 294 >1AQU-A nrPDB Length = 297 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 143/282 (50%), Positives = 201/282 (71%) Query: 14 YVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRA 73 +GV + K F + ++ F ARPDDL+I+TYPKSGTTW+S+++ MIY+ GD+EKC Sbjct: 16 EFRGVLMDKRFTKYWEDVEMFLARPDDLVIATYPKSGTTWISEVVYMIYKEGDVEKCKED 75 Query: 74 PIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAK 133 IF R+P+LE + + +G++ LK+ +PR++KTHLP LLP + ++ K++Y+ RNAK Sbjct: 76 AIFNRIPYLECRNEDLINGIKQLKEKESPRIVKTHLPPKLLPASFWEKNCKMIYLCRNAK 135 Query: 134 DVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFY 193 DVAVSYY+F M +P P ++ F+EKFM G+V YGSWY HV+ WWE S+ VL++FY Sbjct: 136 DVAVSYYYFLLMITSYPNPKSFSEFVEKFMQGQVPYGSWYDHVKAWWEKSKNSRVLFMFY 195 Query: 194 EDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSIS 253 EDMKE+ +RE+ K++EF+ R E VD ++QHTSF+EMK NP TNYT +P+E M+ +S Sbjct: 196 EDMKEDIRREVVKLIEFLERKPSAELVDRIIQHTSFQEMKNNPSTNYTMMPEEMMNQKVS 255 Query: 254 PFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL 295 PFMRKG+ GDWK F A ERFD Y ++M C++ FR EL Sbjct: 256 PFMRKGIIGDWKNHFPEALRERFDEHYKQQMKDCTVKFRMEL 297 >1Q22-A nrPDB Length = 299 Score = 351 bits (901), Expect = 2e-97, Method: Composition-based stats. Identities = 111/290 (38%), Positives = 172/290 (59%), Gaps = 10/290 (3%) Query: 2 ELIQDTSRPPLEYV--KGVP--LIKYFAEALGPLQSFQ-ARPDDLLISTYPKSGTTWVSQ 56 ++ + + + P EY KGVP + Y E++ ++ Q R DD+ I TYPKSGTTW+ + Sbjct: 6 DISEISQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIE 65 Query: 57 ILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQ 116 I+ +I + GD PI+ R P+ E G +L D +PRL+ +HLP+ + + Sbjct: 66 IICLILKEGDPSWIRSVPIWERAPWCETIV-----GAFSLPDQYSPRLMSSHLPIQIFTK 120 Query: 117 TLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHV 176 K KV+Y+ RN +DV VS YH+ +A +PGT D FL F+ GEV +GSW+ H+ Sbjct: 121 AFFSSKAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHI 180 Query: 177 QEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNP 236 + W + L++ YE+++++ + +++I F+GR L +E + VV H++F MK N Sbjct: 181 KGWLRMKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANT 240 Query: 237 MTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAG 286 M+NYT +P +DH F+RKG+ GDWK FTVAQ+E FD Y ++M G Sbjct: 241 MSNYTLLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRG 290 >1Q1Q-A nrPDB Length = 350 Score = 343 bits (879), Expect = 6e-95, Method: Composition-based stats. Identities = 111/285 (38%), Positives = 169/285 (59%), Gaps = 10/285 (3%) Query: 7 TSRPPLEYV--KGVP--LIKYFAEALGPLQSFQ-ARPDDLLISTYPKSGTTWVSQILDMI 61 + + P EY KGVP + Y E++ ++ Q R DD+ I TYPKSGTTW+ +I+ +I Sbjct: 9 SQKLPGEYFRYKGVPFPVGLYSLESISLAENTQDVRDDDIFIITYPKSGTTWMIEIICLI 68 Query: 62 YQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQ 121 + GD PI+ R P+ E G +L D +PRL+ +HLP+ + + Sbjct: 69 LKEGDPSWIRSVPIWERAPWCETIV-----GAFSLPDQYSPRLMSSHLPIQIFTKAFFSS 123 Query: 122 KVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWE 181 K KV+Y+ RN +DV VS YH+ +A +PGT D FL F+ GEV +GSW+ H++ W Sbjct: 124 KAKVIYMGRNPRDVVVSLYHYSKIAGQLKDPGTPDQFLRDFLKGEVQFGSWFDHIKGWLR 183 Query: 182 LSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYT 241 + L++ YE+++++ + +++I F+GR L +E + VV H++F MK N M+NYT Sbjct: 184 MKGKDNFLFITYEELQQDLQGSVERICGFLGRPLGKEALGSVVAHSTFSAMKANTMSNYT 243 Query: 242 TVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAG 286 +P +DH F+RKG+ GDWK FTVAQ+E FD Y ++M G Sbjct: 244 LLPPSLLDHRRGAFLRKGVCGDWKNHFTVAQSEAFDRAYRKQMRG 288 >1OV4-A nrPDB Length = 293 Score = 320 bits (819), Expect = 6e-88, Method: Composition-based stats. Identities = 100/271 (36%), Positives = 165/271 (60%), Gaps = 7/271 (2%) Query: 17 GVPLIKYFAEALGPLQS-FQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 75 P + + +E L ++ F R +D++I TYPKSGT W+++IL +++ GD + PI Sbjct: 20 AFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSKGDAKWIQSVPI 79 Query: 76 FMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDV 135 + R P++E + G L +T +PRL +HLP+ L P++ K KV+Y+ RN +DV Sbjct: 80 WERSPWVESEI-----GYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLMRNPRDV 134 Query: 136 AVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYED 195 VS Y F+ K +P +W+ + E F G V YGSW+ H+ W + L L YE+ Sbjct: 135 LVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFLLLSYEE 194 Query: 196 MKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPF 255 +K++ R I+KI +F+G++L E ++ +++++SF+ MK+N M+NY+ + +++ + Sbjct: 195 LKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVVDK-TQL 253 Query: 256 MRKGMAGDWKTTFTVAQNERFDADYAEKMAG 286 +RKG++GDWK FTVAQ E FD + EKMA Sbjct: 254 LRKGVSGDWKNHFTVAQAEDFDKLFQEKMAD 284 >1ZD1-A nrPDB Length = 284 Score = 316 bits (811), Expect = 5e-87, Method: Composition-based stats. Identities = 93/278 (33%), Positives = 150/278 (53%), Gaps = 18/278 (6%) Query: 14 YVKGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRA 73 GV L + + + +F RP D+ I TYPKSGT+ + +++ ++ QG D ++ Sbjct: 21 EFHGVRLPPFCRGKMEEIANFPVRPSDVWIVTYPKSGTSLLQEVVYLVSQGADPDEIGLM 80 Query: 74 PIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAK 133 I ++P LE+ P G++ +K+ +PRL+K+HLP LP L + KV+Y+ARN K Sbjct: 81 NIDEQLPVLEYPQP----GLDIIKELTSPRLIKSHLPYRFLPSDLHNGDSKVIYMARNPK 136 Query: 134 DVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFY 193 D+ VSYY F+ + GT+ F +FM ++ YGSW++HVQE+WE VL+L Y Sbjct: 137 DLVVSYYQFHRSLRTMSYRGTFQEFCRRFMNDKLGYGSWFEHVQEFWEHRMDSNVLFLKY 196 Query: 194 EDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSIS 253 EDM + ++++ F+G S + ++ + +H + N +P Sbjct: 197 EDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHC---HQLVDQCCNAEALP--------- 244 Query: 254 PFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSF 291 + +G G WK FTV+ NE+FD Y +KM C L+F Sbjct: 245 --VGRGRVGLWKDIFTVSMNEKFDLVYKQKMGKCDLTF 280 >5X2B-D nrPDB Length = 281 Score = 297 bits (761), Expect = 3e-81, Method: Composition-based stats. Identities = 97/267 (36%), Positives = 139/267 (52%), Gaps = 17/267 (6%) Query: 26 EALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFK 85 E LG L SF AR DD+ + +YPKSGT W++++++ I G I + P Sbjct: 18 ELLGSLDSFDAREDDIFLVSYPKSGTHWLAEVIERIPDAG---------ITLTSPI---- 64 Query: 86 APGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHM 145 G S E LK P R + THL +LP T+ ++ K++Y+ RN KD AVS +H+Y Sbjct: 65 ELGDISKFEELKRIPKRRAIPTHLNYEMLPVTVKQKQCKIIYIVRNPKDTAVSMFHYYRD 124 Query: 146 AKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQ 205 P TW +FLE F+ G+V YGSW+ HV W E VL++FYE+MK++ + ++ Sbjct: 125 NPNLPSTETWAAFLELFLKGDVVYGSWFDHVLSWEEHKNDKNVLFIFYEEMKKDFVKSLK 184 Query: 206 KILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISP---FMRKGMAG 262 KI F+G + + + + + TSF EMK N P + S RKG+ G Sbjct: 185 KITAFLGIDVNDSEMAKIARSTSFSEMKSN-AAKENCDPNHVICALTSDRNLVFRKGVVG 243 Query: 263 DWKTTFTVAQNERFDADYAEKMAGCSL 289 DW FT QN FD + EKM + Sbjct: 244 DWINYFTPKQNRGFDELFTEKMRNSDV 270 >1X8L-A nrPDB Length = 351 Score = 273 bits (698), Expect = 6e-74, Method: Composition-based stats. Identities = 77/308 (25%), Positives = 139/308 (45%), Gaps = 34/308 (11%) Query: 16 KGVPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPI 75 KG + + + + + + RP D+ +++Y +SGTT +++ +I + E + Sbjct: 41 KGYMVYRPYLKDAANIYNMPLRPTDVFVASYQRSGTTMTQELVWLIENDLNFEAAK-TYM 99 Query: 76 FMRVPFLEFKAPGIPSGMETLKD-TPAP-------------------------------R 103 +R +L+ P E D P P R Sbjct: 100 SLRYIYLDGFMIYDPEKQEEYNDILPNPENLDMERYLGLLEYSSRPGSSLLAAVPPTEKR 159 Query: 104 LLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFM 163 +KTHLPL+L+P +LD VK+VY+AR+ +DVAVS +H + + + + F E F Sbjct: 160 FVKTHLPLSLMPPNMLD-TVKMVYLARDPRDVAVSSFHHARLLYLLNKQSNFKDFWEMFH 218 Query: 164 VGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFV 223 G + +++HV+E W +L+LFYED ++ I +I +F+G+ L EE + + Sbjct: 219 RGLYTLTPYFEHVKEAWAKRHDPNMLFLFYEDYLKDLPGSIARIADFLGKKLSEEQIQRL 278 Query: 224 VQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEK 283 +H +F++ K N N + + F+RKG AG W+ F ++ + + Sbjct: 279 SEHLNFEKFKNNGAVNMEDYREIGILADGEHFIRKGKAGCWRDYFDEEMTKQAEKWIKDN 338 Query: 284 MAGCSLSF 291 + L + Sbjct: 339 LKDTDLRY 346 >5MEK-A nrPDB Length = 322 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 82/296 (27%), Positives = 129/296 (43%), Gaps = 18/296 (6%) Query: 9 RPPLEYVKGVPLIKYFAEA-LGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGGDL 67 + PL G + E + + FQARP D L+ +YPK+GTTW+ + I Sbjct: 28 KEPLIEYGGYWWLPSLLEGCIHAQEFFQARPSDFLVCSYPKTGTTWLKALTFAIANRSRF 87 Query: 68 EKCHRAPI----FMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKV 123 + + VP++E P P ++ LKD L TH+P LLP +++ Sbjct: 88 DDSSNPLLKRNPHEFVPYIEIDFPFFPE-VDVLKDK-GNTLFSTHIPYELLPDSVVKSGC 145 Query: 124 KVVYVARNAKDVAVSYYHFYHMAKVHPEP-GTWDSFLEKFMVGEVSYGSWYQHVQEWWEL 182 K+VY+ R KD +S + F H + P + + F G YG + H+ +W+ Sbjct: 146 KMVYIWREPKDTFISMWTFLHKERTELGPVSNLEESFDMFCRGLSGYGPYLNHILAYWKA 205 Query: 183 SRTHP--VLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQH-----TSFKEMKKN 235 + +P +L+L YE M+ +P ++ + EF+G E + V SF+ +K N Sbjct: 206 YQENPDRILFLKYETMRADPLPYVKSLAEFMGHGFTAEEEEKGVVEKVVNLCSFETLK-N 264 Query: 236 PMTNYTTVPQEFMD--HSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSL 289 N +E ++ S + RKG GDW T R D EK G L Sbjct: 265 LEANKGEKDREDRPGVYANSAYFRKGKVGDWSNYLTPEMAARIDGLMEEKFKGTGL 320 >1Q44-A nrPDB Length = 326 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 79/276 (28%), Positives = 129/276 (46%), Gaps = 20/276 (7%) Query: 31 LQSFQARPDDLLISTYPKSGTTWVSQILDMIYQGG--DLEKCHRAPI-----FMRVPFLE 83 + F+A+ D+++ T PKSGTTW+ ++ + + P+ + VPFLE Sbjct: 58 QKRFEAKDSDIILVTNPKSGTTWLKALVFALLNRHKFPVSSSGNHPLLVTNPHLLVPFLE 117 Query: 84 FKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFY 143 P P+PRL+ TH+ LP+++ K+VY RN KD+ VS +HF Sbjct: 118 GVYYESPD--FDFSSLPSPRLMNTHISHLSLPESVKSSSCKIVYCCRNPKDMFVSLWHF- 174 Query: 144 HMAKVHPEPGT---WDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHP--VLYLFYEDMKE 198 K+ PE + +E F G+ G ++ H+ E+W SR +P VL++ YE++K+ Sbjct: 175 -GKKLAPEETADYPIEKAVEAFCEGKFIGGPFWDHILEYWYASRENPNKVLFVTYEELKK 233 Query: 199 NPKREIQKILEFVGRSLPEETVDFVVQH-TSFKEMKKNPMTNYTTVPQEFMDHSISPFMR 257 + E+++I EF+ EE + SF+ + + +P + F R Sbjct: 234 QTEVEMKRIAEFLECGFIEEEEVREIVKLCSFESLSNLEVNKEGKLPNGIETKT---FFR 290 Query: 258 KGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRS 293 KG G W+ T + + E D EK G L F S Sbjct: 291 KGEIGGWRDTLSESLAEEIDRTIEEKFKGSGLKFSS 326 >3MGC-A nrPDB Length = 319 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 75/308 (24%), Positives = 121/308 (39%), Gaps = 53/308 (17%) Query: 18 VPLIKYFAEALGPLQSFQARPDDL-LISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF 76 VP + A G Q + + + I++YPK+G TWV +L G K + Sbjct: 15 VPRGSHMASMTGGQQMGRGSMNGIRWIASYPKAGNTWVRCMLAAYITG----KAPQVWND 70 Query: 77 MRVPFLEFKAPGIPSGMETLKDTP-----APRLLKTHLPLALLPQTLL--DQKVKVVYVA 129 + L +A M D P P L+KTHL A +P L + KV+Y+ Sbjct: 71 IDAESLTLEA------MLRFGDLPPAEPMEPVLVKTHLK-ADVPVLGLYGEATAKVLYLV 123 Query: 130 RNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSY------------GSWYQHVQ 177 RN +D+ +S +++ E F KF+ E GSW ++V+ Sbjct: 124 RNPRDMLLSSMRMASISRDDVEKSR--DFARKFIANEGLGWNALGAGGGVGLGSWPENVR 181 Query: 178 EWWELSRTH----PVLYLFYEDMKENPKREIQKILEFVGRSLPEETVD--FVVQHTSFKE 231 W E S VL + YED+K +P +I+EF+ P + D V ++ + Sbjct: 182 SWTESSSDRFPNADVLTMRYEDLKGDPVARFSEIVEFLDLGGPVDIEDIRRAVAASTLER 241 Query: 232 MKKNPMTNYTTVPQEFMDHSISPFMRKGMAG-----------DWKTTFTVAQNERFDADY 280 M++ + + H + M+ G G D +F E ++DY Sbjct: 242 MRELEKRSEQQGGGSPIRHGDARMMKGGPGGARPQFVGEGRYDQSLSF---LGEDIESDY 298 Query: 281 AEKMAGCS 288 E + G S Sbjct: 299 QELLHGDS 306 >3NIB-A nrPDB Length = 309 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 74/299 (24%), Positives = 120/299 (40%), Gaps = 45/299 (15%) Query: 18 VPLIKYFAEALGPLQSFQARPDDL-LISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF 76 VP + A G Q + + + I++YPK+G TW+ +L G K + Sbjct: 15 VPRGSHMASMTGGQQMGRGSMNGIRWIASYPKAGNTWLRCMLAAYITG----KAPQTWKD 70 Query: 77 MRVPFLEFKAPGIPSGMETLKDTP-----APRLLKTHLPLALLPQTLL--DQKVKVVYVA 129 M LE + GM L D P P L+KTHL A +P L + KV+Y+ Sbjct: 71 METVSLELE------GMLHLGDMPPTEPTKPVLVKTHLK-ADVPVLGLYSEATAKVLYLV 123 Query: 130 RNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYG----------SWYQHVQEW 179 RN +D+ +S +++ E +F F+ E SW ++V+ W Sbjct: 124 RNPRDILLSAMRMTAISRDDMESSR--TFARDFIANEGLRMRGRGGGAGLGSWPENVRIW 181 Query: 180 WELSRTH----PVLYLFYEDMKENPKREIQKILEF--VGRSLPEETVDFVVQHTSFKEMK 233 E SR VL + YED+K +P +I+EF +G + E + V + + M+ Sbjct: 182 TESSRDRFPNADVLTMRYEDLKGDPVARFSEIVEFLDLGDPVDIEDIRRAVAACTLERMR 241 Query: 234 KNPMTNYTTV----PQEFMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCS 288 + + PF+ +G D +F E ++ Y E + G S Sbjct: 242 ELEKRSQQQGQWASMTGGRGGEKHPFVGEGRY-DQSLSF---LGEDIESAYQELLHGDS 296 >4EEC-A nrPDB Length = 286 Score = 179 bits (455), Expect = 9e-46, Method: Composition-based stats. Identities = 61/271 (22%), Positives = 106/271 (39%), Gaps = 43/271 (15%) Query: 42 LISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPA 101 I++YPK+G W+ +L G +E I VP LE L+D A Sbjct: 22 WIASYPKAGGHWLRCMLTSYVTGEPVETWPG--IQAGVPHLE----------GLLRDGEA 69 Query: 102 PR-------LLKTHLPLAL-LPQTLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEP- 152 P LL TH + + + KVV + RN +D +S M + PE Sbjct: 70 PSADPDEQVLLATHFTADRPVLRFYRESTAKVVCLIRNPRDAMLSLM---RMKGIPPEDV 126 Query: 153 GTWDSFLEKFMVGE--------VSYGSWYQHVQEWWELSRTH----PVLYLFYEDMKENP 200 E F+ E GSW ++++ W + VL + YED++++P Sbjct: 127 EACRKIAETFIADEGFSSVRIWAGEGSWPENIRSWTDSVHESFPNAAVLAVRYEDLRKDP 186 Query: 201 KREIQKILEFVGRSLPEETVDFVVQHT--SFKEMKK-NPMTNYTTVPQEFMDHSISPFMR 257 + E+ K+++F+ + D V T +EM++ + + T PF+ Sbjct: 187 EGELWKVVDFLELGGRDGVADAVANCTLERMREMEERSKLLGLETTGLMTRGGKQLPFVG 246 Query: 258 KGMAGDWKTTFTVAQNERFDADYAEKMAGCS 288 KG + + + + YA+ + G + Sbjct: 247 KG---GQRKSLKF-MGDDIEKAYADLLHGET 273 >4GBM-A nrPDB Length = 323 Score = 55.4 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 35/224 (15%), Positives = 71/224 (31%), Gaps = 46/224 (20%) Query: 38 PDDLLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIF-----------------MRVP 80 P + I + P+SG+T + +L + H P ++ Sbjct: 32 PGIIFILSSPRSGSTLLRVMLAGHSSLFSPPELHLLPFNTMKERQEQLNLSYLGEGLQKT 91 Query: 81 FLEFKAPGIPSGMETLKDTPA-----------------PRLLKTHLPLALLPQTLLD--- 120 F+E K + +KD + PRLL P + T+L+ Sbjct: 92 FMEVKNLDATASQALIKDLESQNLSIQQVYGMLQENIAPRLLVDKSPTYAMEPTILERGE 151 Query: 121 ---QKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQ 177 K +Y+ R+ V S+ V E+ + Q++ Sbjct: 152 ALFANSKYIYLVRHPYSVIESFVRMRMQKLVGLGEENPYRVAEQ------VWAKSNQNIL 205 Query: 178 EWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVD 221 + + YED+ + P++ + ++ +F+ E + Sbjct: 206 NFLSQLEPERQHQIRYEDLVKKPQQVLSQLCDFLNVPFEPELLQ 249 >1T8T-A nrPDB Length = 271 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 50/138 (36%), Gaps = 19/138 (13%) Query: 117 TLLDQKVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSY------- 169 + + + K++ V R+ A+S Y + P+ T++S F Sbjct: 95 SAMSKDTKLIVVVRDPVTRAISDYTQTLSKR--PDIPTFESL--TFKNRTAGLIDTSWSA 150 Query: 170 ---GSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQH 226 G + +H++ W +L++ E + +P E+ ++ +F+G +H Sbjct: 151 IQIGIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRVQDFLGLKRIITD-----KH 205 Query: 227 TSFKEMKKNPMTNYTTVP 244 F + K P Sbjct: 206 FYFNKTKGFPCLKKAEGS 223 >4GOX-A nrPDB Length = 313 Score = 43.5 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 39/100 (39%), Gaps = 6/100 (6%) Query: 122 KVKVVYVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWE 181 + K +++ R+ V S+ + E + E + + +++ + Sbjct: 148 QAKYIHLVRHPYAVIESFTRLRMDKLLGAEQQNPYALAE------SIWRTSNRNILDLGR 201 Query: 182 LSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVD 221 L + YED+ +P++ + I +F+G E ++ Sbjct: 202 TVGADRYLQVIYEDLVRDPRKVLTNICDFLGVDFDEALLN 241 >3RNL-A nrPDB Length = 311 Score = 41.2 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 47/135 (34%), Gaps = 15/135 (11%) Query: 122 KVKVVYVARNAKDVAVS-YYHFYHMAK--------VHPEPGTWDSFLE--KFMVGEVSYG 170 K++ + RN D A S Y H + + E E + Y Sbjct: 109 DAKILIMLRNPVDRAFSAYMHLVRDERETLSFRESLAKEEERIRQHYEPLWYYRAVGLYA 168 Query: 171 SWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFK 230 + V+ + ++ V + +E+ +P + ++ F+G S + D ++H Sbjct: 169 A---QVKRYLDVFGREQVKVILFEEFARDPVQVVRDCCAFLGVS-TDFVPDTSIRHNESG 224 Query: 231 EMKKNPMTNYTTVPQ 245 K + N+ P Sbjct: 225 VPKSRSLYNFIAKPN 239 >1NST-A nrPDB Length = 325 Score = 36.5 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 64/205 (31%), Gaps = 47/205 (22%) Query: 41 LLISTYPKSGTTWVSQILDM-------IYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGM 93 LLI K+GTT + L M E+ +++ P Sbjct: 50 LLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPS 109 Query: 94 ETLKDTP------------APRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYH 141 T D APR LP K KV+ + N D A S+Y Sbjct: 110 NTTSDFYFEKSANYFDSEVAPRRAAALLP-----------KAKVLTILINPADRAYSWYQ 158 Query: 142 FYHMAKVHPEPGTWD-SFLEKFMVGE-------------VSYGSWYQHVQEWWELSRTHP 187 H +P +F E G + G + H++ W + Sbjct: 159 HQR---AHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQ 215 Query: 188 VLYLFYEDMKENPKREIQKILEFVG 212 +L L + ++ P + + + +F+G Sbjct: 216 ILVLDGKLLRTEPAKVMDMVQKFLG 240 >1ZRH-A nrPDB Length = 274 Score = 35.4 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 36/201 (17%), Positives = 73/201 (36%), Gaps = 22/201 (10%) Query: 42 LISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRV-----PFLEFKAPGIPSGMETL 96 +I K GT + ++L + E + + + P T+ Sbjct: 25 IIIGVRKGGTRALLEMLSLHPDVAAAENEVHFFDWEEHYSHGLGWYLSQMPFSWPHQLTV 84 Query: 97 KDTPAPRLLKTHLPLALLPQTLLDQK--VKVVYVARNAKDVAVSYY---HFYHMAKVHPE 151 + TPA + +P+ + ++++ + R+ + +S Y + HM K P Sbjct: 85 EKTPA------YFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVFYNHMQKHKPY 138 Query: 152 PGTWDSFLEKFMVGEVSYGS-----WYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQK 206 P + FL + V Y + ++ H+Q W + + + + +P EIQK Sbjct: 139 PS-IEEFLVRDGRLNVDYKALNRSLYHVHMQNWLRFFPLRHIHIVDGDRLIRDPFPEIQK 197 Query: 207 ILEFVGRSLPEETVDFVVQHT 227 + F+ S +F T Sbjct: 198 VERFLKLSPQINASNFYFNKT 218 >3F5F-A nrPDB Length = 658 Score = 34.6 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 19/109 (17%), Positives = 36/109 (33%), Gaps = 3/109 (2%) Query: 38 PDDLLISTY--PKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMET 95 DD++I PK+ +T + I + H + + Sbjct: 373 EDDVVIIYNRVPKTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNVTS 432 Query: 96 LKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYVARNAKDVAVSYYHFYH 144 K+ P H+ + + +K + V R+ + VSYY+F Sbjct: 433 WKEM-KPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLR 480 >4ETN-A nrPDB Length = 184 Score = 33.1 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 19/46 (41%), Gaps = 4/46 (8%) Query: 18 VPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQ 63 VP + A G Q + D + + T G T S + + +++ Sbjct: 15 VPRGSHMASMTGGQQMGRGSMDIIFVCT----GNTSRSPMAEALFK 56 >3L7R-A nrPDB Length = 779 Score = 31.2 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 19/49 (38%), Gaps = 3/49 (6%) Query: 18 VPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTT--WVSQILDMIYQG 64 VP + A G Q + + YP+ G W ++++ + G Sbjct: 15 VPRGSHMASMTGGQQMGRGSMTKVSSLGYPRLGENREW-KKLIEAYWAG 62 >3L86-A nrPDB Length = 279 Score = 30.8 bits (68), Expect = 0.66, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 11/27 (40%) Query: 18 VPLIKYFAEALGPLQSFQARPDDLLIS 44 VP + A G Q + D+++ Sbjct: 15 VPRGSHMASMTGGQQMGRGSMKDIIVI 41 >3AP1-A nrPDB Length = 337 Score = 30.8 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 73/205 (35%), Gaps = 35/205 (17%) Query: 41 LLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAP--IFMRVPF-------LEFKAPGIPS 91 + + P+SGTT + +LD + E+ P + MR + L G+ Sbjct: 49 IFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTD 108 Query: 92 GMETL-----------KDTPAPRLLKTHLPLALLPQTLLDQ---KVKVVYVARNAKDVAV 137 + K R+L P L L + K + + R+ + Sbjct: 109 EVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVH 168 Query: 138 SYYHFYHMAKVHPEP-GTWDSFLEKFMVG-EVSYGSWYQHVQEWWELSRTHPVLYLFYED 195 S + ++ L K+ EV Y + E+ + L ++YE Sbjct: 169 SM--ITRKVTIAGFDLSSYRDCLTKWNKAIEVMYA-------QCMEVGKEK-CLPVYYEQ 218 Query: 196 MKENPKREIQKILEFVGRSLPEETV 220 + +P+R ++ IL+F+G + + + Sbjct: 219 LVLHPRRSLKLILDFLGIAWSDAVL 243 >4EGS-A nrPDB Length = 180 Score = 30.4 bits (67), Expect = 0.95, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 17/46 (36%), Gaps = 4/46 (8%) Query: 18 VPLIKYFAEALGPLQSFQARPDDLLISTYPKSGTTWVSQILDMIYQ 63 VP + A G Q + L + T G T S + + I+ Sbjct: 15 VPRGSHMASMTGGQQMGRGSMRVLFVCT----GNTCRSPMAEGIFN 56 >1WDE-A nrPDB Length = 294 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 32/154 (20%), Positives = 58/154 (37%), Gaps = 21/154 (13%) Query: 13 EYVKGVPLIKYFAEALGPLQSFQA--RPDDLLISTYPKSGTTWVSQILDMIYQGGDLEKC 70 E V + + +A + L++ A R D + + +Y G++W+ + + + + Sbjct: 6 EAVTLLLVGWGYAPGMQTLEALDAVRRADVVYVESYTMPGSSWLYKSVVEAAGEARVVEA 65 Query: 71 HRAPIFMRVPFLEFKAPGIPSGMETLKDTPAPRLLKTHLPLALLPQTLLDQKVKVVYV-- 128 R + R + +A + T D P + TH + L L+ V V Y+ Sbjct: 66 SRRDLEERSREIVSRALDAVVAVVTAGD---PMVATTH---SSLAAEALEAGVAVRYIPG 119 Query: 129 ------ARNAKDVAVSYYHFYHMAKVHPEPGTWD 156 AR A +S+Y F PG W Sbjct: 120 VSGVQAARGA--TMLSFYRF---GGTVTLPGPWR 148 >1X3Z-A nrPDB Length = 335 Score = 30.0 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 20/59 (33%), Gaps = 2/59 (3%) Query: 211 VGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTTFT 269 +G P + + K N N T P+ + RKG G+W FT Sbjct: 136 LGSQGPNGEESKF-NCGTVEIYKCNRCGNITRFPRYNDPIKLLE-TRKGRCGEWCNLFT 192 >1WZ2-A nrPDB Length = 967 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 32/84 (38%), Gaps = 12/84 (14%) Query: 127 YVARNAKDVAVSYYHFYHMAKVHPEPGTWDSFLEKFM-VGEVSYGSWYQHVQEWWELSRT 185 YV R DV V P + EK G VS W + V+EWW + Sbjct: 781 YVLRTLADVWVRLM-------APFTPHICEELWEKLGGEGFVSLAKWPEPVEEWWNETIE 833 Query: 186 HPVLYLF--YEDMKENPKREIQKI 207 ++ ED+KE E+ KI Sbjct: 834 AEEEFIRSVMEDIKE--IIEVAKI 855 >6AGH-A nrPDB Length = 339 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 29/83 (34%), Gaps = 6/83 (7%) Query: 194 EDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSIS 253 E + + P+ + F G+ + + F+ +N T + + Sbjct: 163 EAIVKEPEINTTLQMRFFGKRG-----QRKLHYKEFRRFMENLQTEIQEM-EFLQFSKGL 216 Query: 254 PFMRKGMAGDWKTTFTVAQNERF 276 FMRK +W FT +N+ Sbjct: 217 SFMRKEDFAEWLLFFTNTENKDI 239 >5IKB-A nrPDB Length = 257 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 22/56 (39%) Query: 47 PKSGTTWVSQILDMIYQGGDLEKCHRAPIFMRVPFLEFKAPGIPSGMETLKDTPAP 102 P++ TW + ++I + DL R ++F P + G+ L P Sbjct: 64 PEANGTWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRKGTP 119 >4WHN-A nrPDB Length = 183 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 19/41 (46%) Query: 196 MKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKKNP 236 ++ +P + KI EF G + ++ + Q F+ M + Sbjct: 131 IRVDPDSRVGKISEFHGGKIDKKLASKIFQQYHFELMSELK 171 >6EAZ-A nrPDB Length = 379 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 25/69 (36%), Gaps = 6/69 (8%) Query: 208 LEFVGRSLPEETVDFVVQHTSFKEMKKNPMTNYTTVPQEFMDHSISPFMRKGMAGDWKTT 267 + F G+ + + + F+ +N T + + FMRK +W Sbjct: 180 VRFFGKRG-----EKKLHYKEFRRFMENLQTEVQEM-EFLQFSKGLNFMRKEDFAEWLLF 233 Query: 268 FTVAQNERF 276 FT +N+ Sbjct: 234 FTNTENKDI 242 >5Y81-H nrPDB Length = 279 Score = 28.5 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 11/92 (11%), Positives = 32/92 (34%), Gaps = 20/92 (21%) Query: 133 KDVAVSYYHFYHMAKVHPEPGTWDSFLEKFMVGEVSYGSWYQHVQEWWELSRTHPVLYLF 192 ++ + Y + K+ + G + + GS ++ + Sbjct: 181 REKLLKLYRDTVLNKLESKTGNFQKLF------KSPDGSIIKN--------------EIN 220 Query: 193 YEDMKENPKREIQKILEFVGRSLPEETVDFVV 224 YED+K + ++ + +S+ + + V+ Sbjct: 221 YEDIKNETPGSVHELQLILQKSITDGVMRKVI 252 >3LBE-A nrPDB Length = 163 Score = 28.5 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 8/23 (34%) Query: 18 VPLIKYFAEALGPLQSFQARPDD 40 VP + A G Q + D Sbjct: 15 VPRGSHMASMTGGQQMGRGSMSD 37 >2IHB-B nrPDB Length = 153 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 194 EDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKK 234 E++ E+P+ +++ EF+ + EE V F + FK+M+ Sbjct: 36 ENLLEDPEG-VKRFREFLKKEFSEENVLFWLACEDFKKMQD 75 >2I59-A nrPDB Length = 138 Score = 28.5 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 194 EDMKENPKREIQKILEFVGRSLPEETVDFVVQHTSFKEMKK 234 E++ E+P+ +++ EF+ + EE V F + FK+M+ Sbjct: 16 ENLLEDPEG-VKRFREFLKKEFSEENVLFWLACEDFKKMQD 55 >4NV8-A nrPDB Length = 312 Score = 28.1 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 9/23 (39%) Query: 18 VPLIKYFAEALGPLQSFQARPDD 40 VP + A G Q + +D Sbjct: 15 VPRGSHMASNTGGQQMGRGSMND 37 >4M46-A nrPDB Length = 581 Score = 28.1 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 9/23 (39%) Query: 18 VPLIKYFAEALGPLQSFQARPDD 40 VP + A G Q + +D Sbjct: 15 VPRGSHMASMTGGQQMGRGSMED 37 >5MMJ-p nrPDB Length = 88 Score = 27.7 bits (60), Expect = 6.0, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 21/47 (44%), Gaps = 2/47 (4%) Query: 192 FYEDMKENPKREIQKILEFVGRS--LPEETVDFVVQHTSFKEMKKNP 236 FY+ +K + IL+F+ + E D + + FKE + N Sbjct: 38 FYDPIKSQTYLNVPAILDFLEKGAQPTETVYDILKRAEVFKEFRLNQ 84 >5UBJ-A nrPDB Length = 328 Score = 27.3 bits (59), Expect = 9.4, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 27/70 (38%), Gaps = 5/70 (7%) Query: 25 AEALGPLQSFQARPDD---LLISTYPKSGTTWVSQILDMIYQGGDLEKCHRAPIFMR--V 79 + L+ F A P + L+ +TY +GT+W S + D+ + + Sbjct: 45 KDGWASLKDFTAVPYNGQYLVYATYHDTGTSWGSMNFGLFSNWSDMATASQNAMTQSTVA 104 Query: 80 PFLEFKAPGI 89 P L + P Sbjct: 105 PTLFYFEPKD 114 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.137 0.400 Lambda K H 0.267 0.0420 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,385,783 Number of Sequences: 36641 Number of extensions: 508004 Number of successful extensions: 1527 Number of sequences better than 10.0: 49 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1395 Number of HSP's gapped (non-prelim): 85 length of query: 295 length of database: 10,336,785 effective HSP length: 96 effective length of query: 199 effective length of database: 6,819,249 effective search space: 1357030551 effective search space used: 1357030551 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)