BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P50102
         (471 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

4FIP-A nrPDB                                                          976   0.0  
2GFO-A nrPDB                                                          138   5e-33
6DGF-A nrPDB                                                          136   2e-32
5L8W-A nrPDB                                                          134   6e-32
5K1A-A nrPDB                                                          134   8e-32
2Y6E-A nrPDB                                                          133   1e-31
6CPM-C nrPDB                                                          132   3e-31
5L8H-A nrPDB                                                          128   6e-30
3MTN-A nrPDB                                                          123   2e-28
5WCH-A nrPDB                                                          101   6e-22
5J7T-A nrPDB                                                           97   2e-20
5JTV-A nrPDB                                                           96   3e-20
5JTJ-A nrPDB                                                           96   3e-20
5OHN-A nrPDB                                                           96   3e-20
2F1Z-A nrPDB                                                           95   6e-20
5OHK-A nrPDB                                                           92   4e-19
5GVI-A nrPDB                                                           87   1e-17
5CHV-A nrPDB                                                           83   3e-16
6HEH-A nrPDB                                                           77   2e-14
5GJQ-x nrPDB                                                           64   2e-10
5TXK-A nrPDB                                                           63   3e-10
2AYN-A nrPDB                                                           62   6e-10
3IHP-A nrPDB                                                           60   1e-09
3JCR-V nrPDB                                                           52   4e-07
1VJV-A nrPDB                                                           52   5e-07
5MPC-8 nrPDB                                                           52   6e-07
6H4H-A nrPDB                                                           50   2e-06
6H4J-A nrPDB                                                           41   0.001
5O71-A nrPDB                                                           40   0.002
3C5K-A nrPDB                                                           35   0.10 
5G0F-A nrPDB                                                           34   0.18 
1NI3-A nrPDB                                                           33   0.19 
2PVP-A nrPDB                                                           32   0.41 
5WLC-LP nrPDB                                                          29   4.7  
3AXH-A nrPDB                                                           28   8.3  

>4FIP-A nrPDB
          Length = 476

 Score =  976 bits (2522), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 470/471 (99%), Positives = 471/471 (100%)

Query: 1   MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMC 60
           MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMC
Sbjct: 6   MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMC 65

Query: 61  LQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDD 120
           LQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDD
Sbjct: 66  LQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDD 125

Query: 121 VCTKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPD 180
           VCTKTMVPSMERRDGLSGLINMG+TCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPD
Sbjct: 126 VCTKTMVPSMERRDGLSGLINMGNTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPD 185

Query: 181 KCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHE 240
           KCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHE
Sbjct: 186 KCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHE 245

Query: 241 FWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTI 300
           FWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTI
Sbjct: 246 FWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTI 305

Query: 301 DPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVL 360
           DPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVL
Sbjct: 306 DPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVL 365

Query: 361 QLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHK 420
           QLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHK
Sbjct: 366 QLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHK 425

Query: 421 GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN 471
           GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN
Sbjct: 426 GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN 476


>2GFO-A nrPDB
          Length = 396

 Score =  138 bits (348), Expect = 5e-33,   Method: Compositional matrix adjust.
 Identities = 112/358 (31%), Positives = 178/358 (49%), Gaps = 51/358 (14%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
            L+GL N+G+TC+M+SILQCL + P+     ++   + NC     ++         V E 
Sbjct: 61  ALTGLRNLGNTCYMNSILQCLCNAPH-----LADYFNRNCYQDDINRSNLLGHKGEVAEE 115

Query: 195 YG----ALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIH 250
           +G    AL T Q    S    + T          KIN   AGYSQQD+ E   F+++ +H
Sbjct: 116 FGIIMKALWTGQYRYISPKDFKIT--------IGKINDQFAGYSQQDSQELLLFLMDGLH 167

Query: 251 QS----------------YVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQN 294
           +                 ++ D   A+   + + +  E I+  +F+G  +S++ C  C  
Sbjct: 168 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 227

Query: 295 NSKTTIDPFLDLSLDIKDKKK--LYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLGI 351
            S+T  + F+ LSL +    K  L +CL  F K+E+L D N ++C  C + +D++K++ I
Sbjct: 228 KSRT-FEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEI 286

Query: 352 HKLPSVLVLQLKRFEHLLNGS-NRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDI 409
            KLP VL++ LKRF +  +G   +KL   ++FP   L++  Y    + +           
Sbjct: 287 WKLPPVLLVHLKRFSY--DGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKK-------- 336

Query: 410 IYELIGIVSHKGTVNEGHYIAFCKISGGQ-WFKFNDSMVSSISQEEVLKEQAYLLFYT 466
            Y L  + +H G ++ GHY A+CK +  Q WFKF+D  VS IS   V    AY+LFYT
Sbjct: 337 -YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYT 393


>6DGF-A nrPDB
          Length = 370

 Score =  136 bits (343), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 110/357 (30%), Positives = 168/357 (47%), Gaps = 47/357 (13%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           GL+GL N+G+TCFM+SILQCL +      + + +++  +          S A   +V E 
Sbjct: 30  GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDL------HHGSNAHTALVEEF 83

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS-- 252
              + T   SS     N         T   +      GY+QQDA EF +F+++ +H    
Sbjct: 84  AKLIQTIWTSSP----NDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVN 139

Query: 253 --------------YVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT 298
                         ++ D    +++ R   ++ +  +  +F G L+SS+ C  C   S T
Sbjct: 140 RVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCS-T 198

Query: 299 TIDPFLDLSLDIKDKK----KLYECLDSFHKKEQLK-DFNYHCGECNSTQDAIKQLGIHK 353
             DPF DLSL I  +      L +C+  F K++ L  D    C  C   +  IK+  I +
Sbjct: 199 VFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQR 258

Query: 354 LPSVLVLQLKRF-EHLLNGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDIIY 411
            P +LVL LKRF E  +  S  KL  F+ FP   L+++ + S  E   H+        +Y
Sbjct: 259 FPKILVLHLKRFSESRIRTS--KLTTFVNFPLRDLDLREFAS--ENTNHA--------VY 306

Query: 412 ELIGIVSHKGTVNEGHYIAFCKISG-GQWFKFNDSMVSSISQEEVLKEQAYLLFYTI 467
            L  + +H GT   GHY A+C+  G G+W  FNDS V+ +S  +V    AYLLFY +
Sbjct: 307 NLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYEL 363


>5L8W-A nrPDB
          Length = 376

 Score =  134 bits (338), Expect = 6e-32,   Method: Compositional matrix adjust.
 Identities = 105/357 (29%), Positives = 166/357 (46%), Gaps = 53/357 (14%)

Query: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGA 197
           GL+N G+TC+ +S+LQ L    YF R    ++ +   + R  +   +C  D     L+ +
Sbjct: 46  GLVNFGNTCYCNSVLQAL----YFCRPFREKVLAYKSQPRKKESLLTCLAD-----LFHS 96

Query: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDL 257
           + T++         +       +T   K N+    Y QQDAHEF  +++N I      + 
Sbjct: 97  IATQKKKVGVIPPKK------FITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEER 150

Query: 258 PNAKEVSR----------ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLS 307
              K+  R           N+      VH +F+G+L +   C  C+  S    D FLDLS
Sbjct: 151 KQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDED-FLDLS 209

Query: 308 LDIKDKKKLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFE 366
           +D++    +  CL  F   E L  ++ Y+C EC S Q+A K++ + KLP +L L LKRF+
Sbjct: 210 VDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFK 269

Query: 367 HLLNGSNR--KLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT-V 423
           + ++  +R  KL   + FP  L + N          S +   PD +Y+L+ +V H G+  
Sbjct: 270 Y-MDQLHRYTKLSYRVVFPLELRLFN---------TSGDATNPDRMYDLVAVVVHCGSGP 319

Query: 424 NEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLK------------EQAYLLFYTIR 468
           N GHYIA  K S   W  F+D +V  I  + + +            E  Y+LFY  R
Sbjct: 320 NRGHYIAIVK-SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 375


>5K1A-A nrPDB
          Length = 331

 Score =  134 bits (337), Expect = 8e-32,   Method: Compositional matrix adjust.
 Identities = 105/357 (29%), Positives = 166/357 (46%), Gaps = 53/357 (14%)

Query: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGA 197
           GL+N G+TC+ +S+LQ L    YF R    ++ +   + R  +   +C  D     L+ +
Sbjct: 1   GLVNFGNTCYCNSVLQAL----YFCRPFREKVLAYKSQPRKKESLLTCLAD-----LFHS 51

Query: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDL 257
           + T++         +       +T   K N+    Y QQDAHEF  +++N I      + 
Sbjct: 52  IATQKKKVGVIPPKK------FITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEER 105

Query: 258 PNAKEVSR----------ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLS 307
              K+  R           N+      VH +F+G+L +   C  C+  S    D FLDLS
Sbjct: 106 KQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDED-FLDLS 164

Query: 308 LDIKDKKKLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFE 366
           +D++    +  CL  F   E L  ++ Y+C EC S Q+A K++ + KLP +L L LKRF+
Sbjct: 165 VDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFK 224

Query: 367 HLLNGSNR--KLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT-V 423
           + ++  +R  KL   + FP  L + N          S +   PD +Y+L+ +V H G+  
Sbjct: 225 Y-MDQLHRYTKLSYRVVFPLELRLFN---------TSGDATNPDRMYDLVAVVVHCGSGP 274

Query: 424 NEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLK------------EQAYLLFYTIR 468
           N GHYIA  K S   W  F+D +V  I  + + +            E  Y+LFY  R
Sbjct: 275 NRGHYIAIVK-SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 330


>2Y6E-A nrPDB
          Length = 367

 Score =  133 bits (335), Expect = 1e-31,   Method: Compositional matrix adjust.
 Identities = 108/387 (27%), Positives = 173/387 (44%), Gaps = 76/387 (19%)

Query: 129 SMERRDGLSGLINMGSTCFMSSILQCLIHNP----YFIRHSM-SQIHSNNCKVRSPDKCF 183
            M  + GL GL N+G+TCFM+S LQCL +      YF++    ++I+ +N          
Sbjct: 1   GMHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDN---------- 50

Query: 184 SCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQ 243
              +   + E Y  L  +  S        +       T   +     +GY QQD+ E   
Sbjct: 51  PLGMKGEIAEAYAELIKQMWSGRDAHVAPRM----FKTQVGRFAPQFSGYQQQDSQELLA 106

Query: 244 FIINQIHQSY-------VLDLPNA---------KEVSRANNKQCECIVHTVFEGSLESSI 287
           F+++ +H+          L+L +A         KE    +  + + ++   F G  +S++
Sbjct: 107 FLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTL 166

Query: 288 VCPGCQNNSKTTIDPFLDLSLDIKDKK-------------------KLYECLDSFHKKEQ 328
           VCP C   S  T DPF  L+L +  KK                    L +C++ F   E 
Sbjct: 167 VCPECAKVS-VTFDPFCYLTLPLPLKKDRVMEGPMLQPQKKKKTTVALRDCIELFTTMET 225

Query: 329 LKDFN-YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNR----KLDDFIEFP 383
           L + + ++C  C   Q A K+  +  LP +LV+ LKRF +     NR    KLD  +EFP
Sbjct: 226 LGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSY-----NRYWRDKLDTVVEFP 280

Query: 384 TY-LNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKIS-GGQWFK 441
              LNM  +           N      +Y+LI + +H G +  GHY A+ K    G+W+ 
Sbjct: 281 IRGLNMSEFVC---------NLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYY 331

Query: 442 FNDSMVSSISQEEVLKEQAYLLFYTIR 468
           F+DS VS  S+++++ + AY+LFY  R
Sbjct: 332 FDDSNVSLASEDQIVTKAAYVLFYQRR 358


>6CPM-C nrPDB
          Length = 349

 Score =  132 bits (332), Expect = 3e-31,   Method: Compositional matrix adjust.
 Identities = 107/354 (30%), Positives = 168/354 (47%), Gaps = 52/354 (14%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           GL GL N+G+TCFM+S +QCL + P    + ++  +       +P       +   + + 
Sbjct: 18  GLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNP-----LGMRGEIAKS 72

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQ--- 251
           Y  L  KQ  S   S      F    T   +     +GY QQD  E   F+++ +H+   
Sbjct: 73  YAEL-IKQMWSGKFSYVTPRAFK---TQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLN 128

Query: 252 -----SYV--------LDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT 298
                 Y+         D   A+E    + K+ + I+  +F G  +S++VCP C   S  
Sbjct: 129 RIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKIS-V 187

Query: 299 TIDPFLDLSLDIKDKKK----LYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHK 353
           T DPF  L+L +   KK    L +C++ F  KE+L  +  ++C  C   Q A K+L +  
Sbjct: 188 TFDPFCYLTLPLPMPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWS 247

Query: 354 LPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDIIYE 412
           LP VLV+ LKRF +     + KLD  ++FP   L+M   C                  Y 
Sbjct: 248 LPPVLVVHLKRFSYSRYMRD-KLDTLVDFPINDLDMSG-CR-----------------YN 288

Query: 413 LIGIVSHKGTVNEGHYIAFCK-ISGGQWFKFNDSMVSSISQEEVLKEQAYLLFY 465
           LI + +H G +  GHY AF K    G+W+ F+DS VS+ S+++++ + AY+LFY
Sbjct: 289 LIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFY 342


>5L8H-A nrPDB
          Length = 359

 Score =  128 bits (321), Expect = 6e-30,   Method: Compositional matrix adjust.
 Identities = 107/358 (29%), Positives = 164/358 (45%), Gaps = 53/358 (14%)

Query: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGA 197
           GL+N G+TC+++S+LQ L    YF R     + +   + +  +   +C  D     L+ +
Sbjct: 29  GLVNFGNTCYVNSVLQAL----YFCRPFRENVLAYKAQQKKKENLLTCLAD-----LFHS 79

Query: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQI-------- 249
           + T++         +   FI  L    K N     Y QQDAHEF  +++N I        
Sbjct: 80  IATQKKKVGVIPPKK---FISRLR---KENDLFDNYMQQDAHEFLNYLLNTIADILQEEK 133

Query: 250 ---HQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDL 306
               Q+  L   N  E +  NNK     VH +F+G+L +   C  C+  S    D FLDL
Sbjct: 134 KQEKQNGKLKNGNMNEPAE-NNKPELTWVHEIFQGTLTNETRCLNCETVSSKDED-FLDL 191

Query: 307 SLDIKDKKKLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRF 365
           S+D++    +  CL  F   E L  +  Y+C  C S Q+A K++ + KLP +L L LKRF
Sbjct: 192 SVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKRF 251

Query: 366 EHLLNGSN-RKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT-V 423
           +++       KL   + FP  L + N          S +    D +Y+L+ +V H G+  
Sbjct: 252 KYMEQLRRYTKLSYRVVFPLELRLFN---------TSSDAVNLDRMYDLVAVVVHCGSGP 302

Query: 424 NEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLK------------EQAYLLFYTIRQ 469
           N GHYI   K S G W  F+D +V  I  + + +            E  Y+LFY  R+
Sbjct: 303 NRGHYITIVK-SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE 359


>3MTN-A nrPDB
          Length = 373

 Score =  123 bits (309), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 104/379 (27%), Positives = 168/379 (44%), Gaps = 73/379 (19%)

Query: 135 GLSGLINMGSTCFMSSILQCLIH----NPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKI 190
           G  GL N+G+TCF++++LQCL        + +R    Q      + +   + F+      
Sbjct: 21  GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGGGRAQELTEAFA------ 74

Query: 191 VHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIH 250
             ++ GAL    +  +   T  +  F        K   + +GYSQQDA EF + ++ ++H
Sbjct: 75  --DVIGALWHPDSCEAVNPTRFRAVF-------QKYVPSFSGYSQQDAQEFLKLLMERLH 125

Query: 251 -------------------------QSYVLDLPNAKEVSRAN-------NKQCECIVHTV 278
                                       +L+ P   +  RAN        ++   IV  +
Sbjct: 126 LEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVD-L 184

Query: 279 FEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKK------KLYECLDSFHKKEQLKDF 332
           F G L+S + C  C   S TT + F DLSL I  K        L +C + F K+E+L+  
Sbjct: 185 FVGQLKSCLKCQACGYRS-TTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESE 243

Query: 333 NYH-CGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFP-TYLNMKN 390
           N   C  C     + K+L + + P +LVL L RF     GS +K    ++FP   L++ +
Sbjct: 244 NAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSAS-RGSIKKSSVGVDFPLQRLSLGD 302

Query: 391 YCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSI 450
           + S K              +Y+L  + +H G+V+ GHY A C+   G W  +NDS VS +
Sbjct: 303 FASDKAGSP----------VYQLYALCNHSGSVHYGHYTALCRCQTG-WHVYNDSRVSPV 351

Query: 451 SQEEVLKEQAYLLFYTIRQ 469
           S+ +V   + Y+LFY + Q
Sbjct: 352 SENQVASSEGYVLFYQLMQ 370


>5WCH-A nrPDB
          Length = 421

 Score =  101 bits (252), Expect = 6e-22,   Method: Compositional matrix adjust.
 Identities = 97/386 (25%), Positives = 165/386 (42%), Gaps = 78/386 (20%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQI----------------HSNNCKVRS 178
           G  GL N G+TC+M+S++Q L   P  IR+ +  I                  N   V  
Sbjct: 6   GFVGLKNAGATCYMNSVIQQLYMIPS-IRNGILAIEGTGSDVDDDMSGDEKQDNESNVDP 64

Query: 179 PDKCF------------SCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWK- 225
            D  F            S   D+  + + G L   Q      + +R     Y+    WK 
Sbjct: 65  RDDVFGYPQQFEDKPALSKTEDRAAYNI-GVLRHLQVIFGHLAASRLQ--YYVPRGFWKQ 121

Query: 226 ---INQNLAGYSQQDAHEFWQFIINQIHQSY-VLDLPNAKEVSRANNKQCECIVHTVFEG 281
                + +    Q DA EF+  +++ + ++   L  P               ++  V  G
Sbjct: 122 FRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGHP--------------AMLSKVLGG 167

Query: 282 SLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFN-YHCGECN 340
           S     +C GC +  +   + F  L++DI++ + L + L+ + K + L+  N YHC +CN
Sbjct: 168 SFADQKICQGCPHRYECE-ESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCN 226

Query: 341 STQDAIKQLGIHKLPSVLVLQLKRFEHLLNGS-NRKLDDFIEFPTYLNMKNYCSTK---- 395
              D +K+L I KLP VL +QLKRF++        K +D+ EFP  L+M+ Y        
Sbjct: 227 KKVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKL 286

Query: 396 ------------EKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAF-CKISGG----- 437
                       ++ + SE+       Y L+G++ H G  + GHY ++  + +GG     
Sbjct: 287 EGDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERN 346

Query: 438 QWFKFNDSMVSS--ISQEEVLKEQAY 461
           +W+KF+D  V+   +  +E +K Q +
Sbjct: 347 RWYKFDDGDVTECKMDDDEEMKNQCF 372


>5J7T-A nrPDB
          Length = 671

 Score = 97.1 bits (240), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 88/327 (26%), Positives = 139/327 (42%), Gaps = 47/327 (14%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GL N G+TC+M+S+LQ L    +F       ++    +     K    AL ++ +EL
Sbjct: 2   GYVGLKNQGATCYMNSLLQTL----FFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYEL 57

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYV 254
                  Q S     T + T      +  W   + L  + Q D  E  + +++ +     
Sbjct: 58  -------QHSDKPVGTKKLTK-----SFGW---ETLDSFMQHDVQELCRVLLDNVE---- 98

Query: 255 LDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKK 314
                    ++      E  +  +F G + S I C      S    D + D+ L IK KK
Sbjct: 99  ---------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRRED-YYDIQLSIKGKK 148

Query: 315 KLYECLDSFHKKEQLK-DFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH-LLNGS 372
            ++E    +   EQL  D  Y  GE +  Q+A K +    LP VL LQL RF +      
Sbjct: 149 NIFESFVDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQ 207

Query: 373 NRKLDDFIEFPTYLNMKNYCS-TKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAF 431
           N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + GHY+ +
Sbjct: 208 NIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGGHYVVY 258

Query: 432 CKISG-GQWFKFNDSMVSSISQEEVLK 457
               G G+W KF+D +VS  ++EE ++
Sbjct: 259 LNPKGDGKWCKFDDDVVSRCTKEEAIE 285


>5JTV-A nrPDB
          Length = 594

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 88/327 (26%), Positives = 139/327 (42%), Gaps = 47/327 (14%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GL N G+TC+M+S+LQ L    +F       ++    +     K    AL ++ +EL
Sbjct: 21  GYVGLKNQGATCYMNSLLQTL----FFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYEL 76

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYV 254
                  Q S     T + T      +  W   + L  + Q D  E  + +++ +     
Sbjct: 77  -------QHSDKPVGTKKLTK-----SFGW---ETLDSFMQHDVQELCRVLLDNVE---- 117

Query: 255 LDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKK 314
                    ++      E  +  +F G + S I C      S    D + D+ L IK KK
Sbjct: 118 ---------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRRED-YYDIQLSIKGKK 167

Query: 315 KLYECLDSFHKKEQLK-DFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH-LLNGS 372
            ++E    +   EQL  D  Y  GE +  Q+A K +    LP VL LQL RF +      
Sbjct: 168 NIFESFVDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQ 226

Query: 373 NRKLDDFIEFPTYLNMKNYC-STKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAF 431
           N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + GHY+ +
Sbjct: 227 NIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGGHYVVY 277

Query: 432 CKISG-GQWFKFNDSMVSSISQEEVLK 457
               G G+W KF+D +VS  ++EE ++
Sbjct: 278 LNPKGDGKWCKFDDDVVSRCTKEEAIE 304


>5JTJ-A nrPDB
          Length = 387

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 90/330 (27%), Positives = 140/330 (42%), Gaps = 53/330 (16%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GL N G+TC+M+S+LQ L    +F       ++    +     K    AL ++ +EL
Sbjct: 21  GYVGLKNQGATCYMNSLLQTL----FFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYEL 76

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYV 254
                  Q S     T + T      +  W   + L  + Q D  E  + +++ +     
Sbjct: 77  -------QHSDKPVGTKKLTK-----SFGW---ETLDSFMQHDVQELCRVLLDNVE---- 117

Query: 255 LDLPNAKEVSRANNKQCECIVHTV---FEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIK 311
                       N  +  C+  T+   F G + S I C      S    D + D+ L IK
Sbjct: 118 ------------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRRED-YYDIQLSIK 164

Query: 312 DKKKLYECLDSFHKKEQLK-DFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH-LL 369
            KK ++E    +   EQL  D  Y  GE +  Q+A K +    LP VL LQL RF +   
Sbjct: 165 GKKNIFESFVDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQ 223

Query: 370 NGSNRKLDDFIEFPTYLNMKNYC-STKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHY 428
              N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + GHY
Sbjct: 224 TDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGGHY 274

Query: 429 IAFCKISG-GQWFKFNDSMVSSISQEEVLK 457
           + +    G G+W KF+D +VS  ++EE ++
Sbjct: 275 VVYLNPKGDGKWCKFDDDVVSRCTKEEAIE 304


>5OHN-A nrPDB
          Length = 370

 Score = 95.9 bits (237), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 94/382 (24%), Positives = 152/382 (39%), Gaps = 72/382 (18%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIR--HSMSQIHSNNCKVRSPDKCFSCALDKIVHE 193
           + GL+N+G+TCFM+S+LQ L   P FIR     +  +S + K   P   +       + +
Sbjct: 6   VPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQK-EPPSHQYLSLTLLHLLK 64

Query: 194 LYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIIN------ 247
                   Q  +     +       L    W+I    + + +QDAHE +  I +      
Sbjct: 65  ALSC----QEVTDDEVLDASCLLDVLRMYRWQI----SSFEEQDAHELFHVITSSLEDER 116

Query: 248 --QIHQSYVLDLPNAKEVSRANNKQCECIVHT-------------VFEGSLESSIVCPGC 292
             Q   +++ D+ + ++ S    KQ  C                  F G L S++VC  C
Sbjct: 117 DRQPRVTHLFDVHSLEQQSEITPKQITCRTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHC 176

Query: 293 QNNSKTTIDPFLDLSLDIKDKK-----KLYECLDSFHKKEQLKDFNYHCGECNSTQDA-- 345
           ++ S    D F  LSL I          L  CL  F   E ++D    C  C   +    
Sbjct: 177 EHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVV--CDNCTKIEAKGT 234

Query: 346 -------------IKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYC 392
                        +KQL + KLP  L + L+R     +G+  K  + ++F   L+M  Y 
Sbjct: 235 LNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEDLDMDEY- 293

Query: 393 STKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCK---------ISGGQWFKFN 443
                 K+  N      ++ L+ +V H G ++ GH++ + +          +  QW   +
Sbjct: 294 ------KYHSNAST--YLFRLMAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVS 345

Query: 444 DSMVSSISQEEVLKEQAYLLFY 465
           D  V   S +EVL   AYLLFY
Sbjct: 346 DDTVRKASLQEVLSSSAYLLFY 367


>2F1Z-A nrPDB
          Length = 522

 Score = 95.1 bits (235), Expect = 6e-20,   Method: Compositional matrix adjust.
 Identities = 90/330 (27%), Positives = 140/330 (42%), Gaps = 53/330 (16%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GL N G+TC+M+S+LQ L    +F       ++    +     K    AL ++ +EL
Sbjct: 174 GYVGLKNQGATCYMNSLLQTL----FFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYEL 229

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYV 254
                  Q S     T + T      +  W   + L  + Q D  E  + +++ +     
Sbjct: 230 -------QHSDKPVGTKKLTK-----SFGW---ETLDSFMQHDVQELCRVLLDNVE---- 270

Query: 255 LDLPNAKEVSRANNKQCECIVHTV---FEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIK 311
                       N  +  C+  T+   F G + S I C      S    D + D+ L IK
Sbjct: 271 ------------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRRED-YYDIQLSIK 317

Query: 312 DKKKLYECLDSFHKKEQLK-DFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH-LL 369
            KK ++E    +   EQL  D  Y  GE +  Q+A K +    LP VL LQL RF +   
Sbjct: 318 GKKNIFESFVDYVAVEQLDGDNKYDAGE-HGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQ 376

Query: 370 NGSNRKLDDFIEFPTYLNMKNYCS-TKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHY 428
              N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + GHY
Sbjct: 377 TDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGGHY 427

Query: 429 IAFCKISG-GQWFKFNDSMVSSISQEEVLK 457
           + +    G G+W KF+D +VS  ++EE ++
Sbjct: 428 VVYLNPKGDGKWCKFDDDVVSRCTKEEAIE 457


>5OHK-A nrPDB
          Length = 336

 Score = 92.0 bits (227), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 91/361 (25%), Positives = 147/361 (40%), Gaps = 64/361 (17%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIR--HSMSQIHSNNCKVRSPDKCFSCALDKIVHE 193
           + GL+N+G+TCFM+S+LQ L   P FIR     +  +S + K   P   +       + +
Sbjct: 6   VPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQK-EPPSHQYLSLTLLHLLK 64

Query: 194 LYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY 253
                   Q  +     +       L    W+I    + + +QDAHE +  I +      
Sbjct: 65  ALSC----QEVTDDEVLDASCLLDVLRMYRWQI----SSFEEQDAHELFHVITS------ 110

Query: 254 VLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDK 313
              L + ++ S ++ K         F G L S++VC  C++ S    D F  LSL I   
Sbjct: 111 --SLEDERDGSGSHWKS-----QHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAA 163

Query: 314 K-----KLYECLDSFHKKEQLKDFNYHCGECNSTQDA---------------IKQLGIHK 353
                  L  CL  F   E ++D    C  C   +                 +KQL + K
Sbjct: 164 TWGHPLTLDHCLHHFISSESVRDVV--CDNCTKIEAKGTLNGEKVEHQRTTFVKQLKLGK 221

Query: 354 LPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYEL 413
           LP  L + L+R     +G+  K  + ++F   L+M  Y       K+  N      ++ L
Sbjct: 222 LPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEDLSMDEY-------KYHSNAST--YLFRL 272

Query: 414 IGIVSHKGTVNEGHYIAFCK---------ISGGQWFKFNDSMVSSISQEEVLKEQAYLLF 464
           + +V H G ++ GH++ + +          +  QW   +D  V   S +EVL   AYLLF
Sbjct: 273 MAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSSAYLLF 332

Query: 465 Y 465
           Y
Sbjct: 333 Y 333


>5GVI-A nrPDB
          Length = 444

 Score = 87.4 bits (215), Expect = 1e-17,   Method: Compositional matrix adjust.
 Identities = 101/440 (22%), Positives = 159/440 (36%), Gaps = 115/440 (26%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELY 195
           + GL+N+G+T FM+S+LQ L   P FIR  +    S N   R   +     L + + +L 
Sbjct: 6   VPGLLNLGNTAFMNSLLQGLAACPSFIRW-LEDFTSQNSADRERTE-RETQLSRSLMQLL 63

Query: 196 GALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQ---- 251
            AL     SS     +       LL        +++ + +QDAHE +  + + + +    
Sbjct: 64  KAL-----SSHVPGEDDVLDAGGLLEALRLYRWHISSFEEQDAHELFHVLTSSLEEEQER 118

Query: 252 ----SYVLDLPNAKEVSRANNKQCEC----IVHTV---------FEGSLESSIVCPGCQN 294
               +++ D+   ++   +  K   C     +H +         F G L S + C  C+ 
Sbjct: 119 QPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHPIPSLWRTRHPFHGRLTSYMACKRCEQ 178

Query: 295 NSKTTIDPFLDLSLDIKDKK-----KLYECLDSFHKKEQLKDFNYHCGECNSTQDA---- 345
            S    D F  LSL I   +      L +CL  F   E +K+    C  C   Q      
Sbjct: 179 QSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKEVE--CENCTKQQAGELVN 236

Query: 346 -----------IKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNY--- 391
                      +KQL + KLP  L + L+R      GS  K  + ++F  YL++  Y   
Sbjct: 237 GEVLESQRTTFVKQLKLGKLPQCLCIHLQRLTWSKEGSPIKRQEHVQFTEYLSLDRYKHC 296

Query: 392 ----------------CSTKEKD---------------KHSENGKVPDI----------- 409
                            S   KD               K   NG  P +           
Sbjct: 297 SAAQSQQKTSRTNKAKASADPKDKAIANGVDSEHCNNNKPQSNGTFPSVFLHSPGLSSQL 356

Query: 410 -----------IYELIGIVSHKGTVNEGHYIAFCKISGG---------QWFKFNDSMVSS 449
                      ++ L  ++ H G ++ GH+I + +             QW   +D  V  
Sbjct: 357 NLTYDYSTSEYLFRLTAVLVHHGDMHSGHFITYRRCPAAPRGTSPFSSQWLWVSDDSVRK 416

Query: 450 ISQEEVLKEQAYLLFYTIRQ 469
            S +EVL   AYLLFY   Q
Sbjct: 417 ASLQEVLSSSAYLLFYERMQ 436


>5CHV-A nrPDB
          Length = 323

 Score = 82.8 bits (203), Expect = 3e-16,   Method: Compositional matrix adjust.
 Identities = 91/350 (26%), Positives = 146/350 (41%), Gaps = 53/350 (15%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYF--IRHSMSQIHSNNCKVRSPDKCFSCALDKIVH 192
           GL GL N+G TC ++S+LQ  + N  F  I   ++   S   + RS        L+K+  
Sbjct: 5   GLVGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPFQLLLLLEKMQ- 63

Query: 193 ELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS 252
                 +++Q +   T          L+ C  K N  L  + Q DA + +  I N + + 
Sbjct: 64  ------DSRQKAVLPTE---------LVQCLQKYNVPL--FVQHDAAQLYLTIWN-LTKD 105

Query: 253 YVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKD 312
            + D    + +              +F    + S++C GC   S       L LSL + D
Sbjct: 106 QITDTDLTERL------------QGLFTIWTQESLICVGCTAESSRR-SKLLTLSLPLFD 152

Query: 313 K-----KKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH 367
           K     K L + L  F + ++L   +  C  C       + L +  LP  L + L RF  
Sbjct: 153 KDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLMRFSA 212

Query: 368 LLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGH 427
             N    K+   + FP  L+      T+E     +  +  +I YEL  +++H G  + GH
Sbjct: 213 R-NSRTEKICHSVNFPQSLDFSQVLPTEED--LGDTKEQSEIHYELFAVIAHVGMADFGH 269

Query: 428 YIAFCK-ISGGQWFKFNDSMVSSISQEEV----------LKEQAYLLFYT 466
           Y A+ +    G+WF FNDS V  ++ ++V           +E AYLL YT
Sbjct: 270 YCAYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYGNHRYRWRETAYLLVYT 319


>6HEH-A nrPDB
          Length = 382

 Score = 77.0 bits (188), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 86/337 (25%), Positives = 144/337 (42%), Gaps = 44/337 (13%)

Query: 132 RRDGLS-GLINMGSTCFMSSILQCLIHNPYFIR----HSMSQIHSNNCKVRSPDK--CFS 184
           R DG   GL N+G+TC+ S+++Q L   P F R    +S+ Q    NC+  +  +   F 
Sbjct: 9   RVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFM 68

Query: 185 CALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQF 244
             L  +   + G+ N K    S+         + LL  A++ ++      QQD  EF   
Sbjct: 69  QELQYLFALMMGS-NRKFVDPSAA--------LDLLKGAFRSSEE----QQQDVSEFTHK 115

Query: 245 IINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVF-EGSLESSIVCPGCQNNSKTTIDPF 303
           +++ +  ++ L +      +++ N   +    T   EG  E     P C N +      F
Sbjct: 116 LLDWLEDAFQLAVNVNSPRNKSENPMVQLFYGTFLTEGVREGK---PFCNNET------F 166

Query: 304 LDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLK 363
               L +   + L ECL+       + + +      + +    ++    KLP VL  +L 
Sbjct: 167 GQYPLQVNGYRNLDECLEG-----AMVEGDVELLPSDHSVKYGQERWFTKLPPVLTFELS 221

Query: 364 RFEHLLN-GSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT 422
           RFE   + G   K+ + +EFP  + M  Y         S + +VP   Y L  ++ H+G 
Sbjct: 222 RFEFNQSLGQPEKIHNKLEFPQIIYMDRYMY----GSGSGSRQVP---YRLHAVLVHEGQ 274

Query: 423 VNEGHYIAFCKISGGQ-WFKFNDSMVSSISQEEVLKE 458
            N GHY A+      Q W K+ND  V+  S EEV ++
Sbjct: 275 ANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERD 311


>5GJQ-x nrPDB
          Length = 494

 Score = 63.5 bits (153), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 99/444 (22%), Positives = 183/444 (41%), Gaps = 77/444 (17%)

Query: 87  INSNNGLLFCFKCEDYIGNIDLINDAILAK--YWDDVCTKTMVPSMERRDGLSGLINMGS 144
           I   NG+         +G+ D + +   AK  + +D+  + +  +ME      GL N+G+
Sbjct: 61  IKIKNGMTLLM-----MGSADALPEEPSAKTVFVEDMTEEQLASAMELP---CGLTNLGN 112

Query: 145 TCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQAS 204
           TC+M++ +QC+   P  ++ ++ +       +R+  +  S     I   L    ++   +
Sbjct: 113 TCYMNATVQCIRSVPE-LKDALKRYAG---ALRASGEMASAQY--ITAALRDLFDSMDKT 166

Query: 205 SSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY-VLDLPNAKEV 263
           SSS        F+++    +        Y QQDA+E W  ++  + Q    ++  + KE 
Sbjct: 167 SSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKET 226

Query: 264 S-----RANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTT-IDPFLDLSLDI-KDKKKL 316
                  A   + + ++   F    E+++ C   +    T   +  L LS  I ++ K L
Sbjct: 227 DSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL 286

Query: 317 YECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGS-NRK 375
           +  L    ++E  K               IK   I +LP+ L +Q+ RF +    S N K
Sbjct: 287 FTGLKLRLQEEITK----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAK 342

Query: 376 LDDFIEFPTYLNMKNYC---------STKEKDKHSENGKV-------------------- 406
           +   ++FP  L+M   C         S + K K  E+ KV                    
Sbjct: 343 VLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYE 402

Query: 407 -----PDI------IYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEE 454
                 DI       Y+L  +++H+G + + GHY+++ K    +W KF+D  VS ++ E+
Sbjct: 403 PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPED 462

Query: 455 VLKEQ-------AYLLFYTIRQVN 471
           +L+         AY+L Y  R+V 
Sbjct: 463 ILRLSGGGDWHIAYVLLYGPRRVE 486


>5TXK-A nrPDB
          Length = 372

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 92/372 (24%), Positives = 147/372 (39%), Gaps = 72/372 (19%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GLIN+G+T +++SILQ L     F RH + ++  NN          S  L   +  L
Sbjct: 17  GKIGLINLGNTSYVNSILQALFMASDF-RHCVLRLTENN----------SQPLMTKLQWL 65

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS-- 252
           +G L   Q  + S            L+ +W      +  +QQD  E+ +++++++H+   
Sbjct: 66  FGFLEHSQRPAISPEN--------FLSASW--TPWFSPGTQQDCSEYLKYLLDRLHEEEK 115

Query: 253 ------YVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDL 306
                   L   ++              V  +F G + + I C  C N S    + F DL
Sbjct: 116 TGTRICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSSRE-EAFTDL 174

Query: 307 SLDI-----KDKKKLYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLGIHKLPSVLVL 360
           SL       +  + + + ++ F   E+L   N Y+C  C S QDA K + + + P  L+L
Sbjct: 175 SLAFPPPGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLIL 234

Query: 361 QLKRFE-HLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSH 419
            L RF   L     RK+ D +  P  L +               G+  D+      +V  
Sbjct: 235 TLLRFSFDLRTMRRRKILDDVSIPLLLRLP---------LAGGRGQAYDLC---SVVVHS 282

Query: 420 KGTVNEGHYIAFCKISGG----------------QWFKFNDSMVSSISQEEVL------- 456
             +   GHY  + +                    QW+ FND+ VS  S E V        
Sbjct: 283 GVSSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFP 342

Query: 457 KEQAYLLFYTIR 468
           K+ AY+LFY  R
Sbjct: 343 KDTAYVLFYRQR 354


>2AYN-A nrPDB
          Length = 404

 Score = 61.6 bits (148), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 89/391 (22%), Positives = 162/391 (41%), Gaps = 67/391 (17%)

Query: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGA 197
           GL N+G+TC+M++ +QC+   P  ++ ++ +       +R+  +  S     I   L   
Sbjct: 16  GLTNLGNTCYMNATVQCIRSVPE-LKDALKRYAG---ALRASGEMASAQY--ITAALRDL 69

Query: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY-VLD 256
            ++   +SSS        F+++    +        Y QQDA+E W  ++  + Q    ++
Sbjct: 70  FDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIE 129

Query: 257 LPNAKEVS-----RANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTT-IDPFLDLSLDI 310
             + KE        A   + + ++   F    E+++ C   +    T   +  L LS  I
Sbjct: 130 DDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFI 189

Query: 311 -KDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLL 369
            ++ K L+  L    ++E  K               IK   I +LP+ L +Q+ RF +  
Sbjct: 190 NQEVKYLFTGLKLRLQEEITK----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKE 245

Query: 370 NGS-NRKLDDFIEFPTYLNMKNYC---------STKEKDKHSENGKV------------- 406
             S N K+   ++FP  L+M   C         S + K K  E+ KV             
Sbjct: 246 KESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSP 305

Query: 407 ------------PDI------IYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMV 447
                        DI       Y+L  +++H+G + + GHY+++ K    +W KF+D  V
Sbjct: 306 QKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKV 365

Query: 448 SSISQEEVLKEQ-------AYLLFYTIRQVN 471
           S ++ E++L+         AY+L Y  R+V 
Sbjct: 366 SIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 396


>3IHP-A nrPDB
          Length = 854

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 74/321 (23%), Positives = 123/321 (38%), Gaps = 63/321 (19%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHS--NNCKVRSPDKCFSCALDKIVH 192
           G +G+ N+G++C+++S++Q L   P F R  + ++     N     P + FS  + K+ H
Sbjct: 343 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPT-DPTQDFSTQVAKLGH 401

Query: 193 ELYGALNTKQASSSSTSTNR------QTGFIYLLTCAW--KINQNLAGYSQQDAHEFWQF 244
            L     +K    S            Q G    +  A   K +   +   QQDA EF+  
Sbjct: 402 GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLH 461

Query: 245 IINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT-TIDPF 303
           +IN + +       N +     N          VF   +E  I C   +    T  +D  
Sbjct: 462 LINMVER-------NCRSSENPNE---------VFRFLVEEKIKCLATEKVKYTQRVDYI 505

Query: 304 LDLSLDI--------------------KDKKKLYE----------CLDSFHKKEQLKDFN 333
           + L + +                    ++K  L E          CL+++   EQ+ DF 
Sbjct: 506 MQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFW 565

Query: 334 YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCS 393
               +  S   A+K       P  LV+Q+K+F   L+   +KLD  IE P  L++     
Sbjct: 566 STALQAKSV--AVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRG 623

Query: 394 TKEKDKHSENGKVPDIIYELI 414
           T  +    E   +PDI   L+
Sbjct: 624 TGLQPGEEE---LPDIAPPLV 641


>3JCR-V nrPDB
          Length = 565

 Score = 52.4 bits (124), Expect = 4e-07,   Method: Compositional matrix adjust.
 Identities = 95/462 (20%), Positives = 178/462 (38%), Gaps = 89/462 (19%)

Query: 57  TFMCLQCG--FCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAI- 113
            + CL CG  F G    SH   HS Q  H   +N +    +C        N ++I+ ++ 
Sbjct: 133 AYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLP-----DNYEIIDSSLE 187

Query: 114 -LAKYWDDVCTKTMVPSMERR-------------DGLSGLINMGSTCFMSSILQCLIHNP 159
            +        TK  + +++++              G+ GL N+ +  + +++LQ L + P
Sbjct: 188 DITYVLKPTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVP 247

Query: 160 YFIRHSMSQIHSNNCKVRSPDKCFSCA--LDKIVHELYGALNTKQASSSSTSTNRQTGFI 217
               + + + +  N K    D  F       +++ +L+   N K   S            
Sbjct: 248 PLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQA----- 302

Query: 218 YLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHT 277
            ++ C+ K  Q      Q D  +F  + +N +H +                K+ + IV  
Sbjct: 303 -VVLCSKKTFQIT---KQGDGVDFLSWFLNALHSALG-----------GTKKKKKTIVTD 347

Query: 278 VFEGSLE---SSIVCPGCQNNSKTTI------------DPFLDLSLDI------KDKKK- 315
           VF+GS+      +  P      K  +              F+ L+LD+      KD+K+ 
Sbjct: 348 VFQGSMRIFTKKLPHPDLPAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQ 407

Query: 316 -------LYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHL 368
                  L+  L  F+   + +   Y        ++ +K+  + KLP  L+  +KRF   
Sbjct: 408 LIIPQVPLFNILAKFNGITEKEYKTY-------KENFLKRFQLTKLPPYLIFCIKRFTKN 460

Query: 369 LNGSNRKLDDFIEFP-TYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGH 427
            N    K    + FP T ++++ Y S + +  H       +  Y+LI  + H G  +EG 
Sbjct: 461 -NFFVEKNPTIVNFPITNVDLREYLSEEVQAVHK------NTTYDLIANIVHDGKPSEGS 513

Query: 428 Y-IAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIR 468
           Y I       G+W++  D  V+ I  + +   +AY+  +  R
Sbjct: 514 YRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRR 555


>1VJV-A nrPDB
          Length = 415

 Score = 52.0 bits (123), Expect = 5e-07,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 38/57 (66%), Gaps = 3/57 (5%)

Query: 402 ENGKVPDIIYELIGIVSHKGTVNE-GHYIAFCK--ISGGQWFKFNDSMVSSISQEEV 455
           E G+ P  +Y LIG+++H+G  +E GHY AF +  +   +W+KFND  VS + +E++
Sbjct: 337 EKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKI 393


>5MPC-8 nrPDB
          Length = 499

 Score = 52.0 bits (123), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 23/57 (40%), Positives = 38/57 (66%), Gaps = 3/57 (5%)

Query: 402 ENGKVPDIIYELIGIVSHKGTVNE-GHYIAFCK--ISGGQWFKFNDSMVSSISQEEV 455
           E G+ P  +Y LIG+++H+G  +E GHY AF +  +   +W+KFND  VS + +E++
Sbjct: 421 EKGENPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKI 477


>6H4H-A nrPDB
          Length = 560

 Score = 50.1 bits (118), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 67/271 (24%), Positives = 115/271 (42%), Gaps = 40/271 (14%)

Query: 132 RRDGLS-GLINMGSTCFMSSILQCLIHNPYFIR----HSMSQIHSNNCKVRSPDK--CFS 184
           R DG   GL N+G+TC+ S+++Q L   P F R    +S+ Q    NC+  +  +   F 
Sbjct: 9   RVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFM 68

Query: 185 CALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQF 244
             L  +   + G+ N K    S+         + LL  A++ ++      QQD  EF   
Sbjct: 69  QELQYLFALMMGS-NRKFVDPSAA--------LDLLKGAFRSSEE----QQQDVSEFTHK 115

Query: 245 IINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVC---PGCQNNSKTTID 301
           +++ +  ++ L    A  V+   NK    +V  +F G+  +  V    P C N +     
Sbjct: 116 LLDWLEDAFQL----AVNVNSPRNKSENPMVQ-LFYGTFLTEGVREGKPFCNNET----- 165

Query: 302 PFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQ 361
            F    L +   + L ECL+       + + +      + +    ++    KLP VL  +
Sbjct: 166 -FGQYPLQVNGYRNLDECLEG-----AMVEGDVELLPSDHSVKYGQERWFTKLPPVLTFE 219

Query: 362 LKRFEHLLN-GSNRKLDDFIEFPTYLNMKNY 391
           L RFE   + G   K+ + +EFP  + M  Y
Sbjct: 220 LSRFEFNQSLGQPEKIHNKLEFPQIIYMDRY 250



 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)

Query: 409 IIYELIGIVSHKGTVNEGHYIAFCKISGGQ-WFKFNDSMVSSISQEEVLKE 458
           + Y L  ++ H G  N GHY A+      Q W K+ND  V+  S EEV ++
Sbjct: 435 VPYRLHAVLVHDGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERD 485


>6H4J-A nrPDB
          Length = 552

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 54/259 (20%), Positives = 111/259 (42%), Gaps = 27/259 (10%)

Query: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCK--VRSPDKCFSCALDKIVHELY 195
           GL N+G+TC+ S+++Q L +   F R  ++    +N +   R+  +  +    + +  L+
Sbjct: 16  GLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYLF 75

Query: 196 GAL-NTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYV 254
             L  TK+     +        + +L  A+K N +     QQD  EF   +++ +  ++ 
Sbjct: 76  ALLVGTKRKYVDPSRA------VEILKDAFKSNDS----QQQDVSEFTHKLLDWLEDAFQ 125

Query: 255 LDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKK 314
           +      +  +  N   E     +F G   +  V  G +  +      F    L +   K
Sbjct: 126 MKAEEETDEEKPKNPMVE-----LFYGRFLAVGVLEGKKFENTEM---FGQYPLQVNGFK 177

Query: 315 KLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFE-HLLNGSN 373
            L+ECL++   + +++  +       ++  + ++    +LP VL  +L RFE +   G  
Sbjct: 178 DLHECLEAAMIEGEIESLH-----SENSGKSGQEHWFTELPPVLTFELSRFEFNQALGRP 232

Query: 374 RKLDDFIEFPTYLNMKNYC 392
            K+ + +EFP  L +  Y 
Sbjct: 233 EKIHNKLEFPQVLYLDRYM 251



 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 409 IIYELIGIVSHKGTVNEGHYIAFC-KISGGQWFKFNDSMVSSISQEEVLKE 458
           + Y L  ++ H+G  N GHY A+       +W K+ND  V+  S EE++++
Sbjct: 435 VPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRD 485


>5O71-A nrPDB
          Length = 716

 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 61/290 (21%), Positives = 124/290 (42%), Gaps = 31/290 (10%)

Query: 110 NDAILAKYWDDVCTKTMVPSMERRDGLS--GLINMGSTCFMSSILQCLIHNPYFIRHSMS 167
           N A L +   +V   +  P   +R   +  GL N+G+TC+ S+++Q L +   F R  ++
Sbjct: 142 NKACLKRTPTEVWRDSRNPYDRKRQDKAPVGLKNVGNTCWFSAVIQSLFNLLEFRRLVLN 201

Query: 168 QIHSNNCK--VRSPDKCFSCALDKIVHELYGAL-NTKQASSSSTSTNRQTGFIYLLTCAW 224
               +N +   R+  +  +    + +  L+  L  TK+     +        + +L  A+
Sbjct: 202 YKPPSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRA------VEILKDAF 255

Query: 225 KINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLE 284
           K N +     QQD  EF   +++ +  ++ +      +  +  N   E     +F G   
Sbjct: 256 KSNDS----QQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVE-----LFYGRFL 306

Query: 285 SSIVCPGCQ-NNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQ 343
           +  V  G +  N++     F    L +   K L+ECL++   + +++  +       ++ 
Sbjct: 307 AVGVLEGKKFENTEM----FGQYPLQVNGFKDLHECLEAAMIEGEIESLH-----SENSG 357

Query: 344 DAIKQLGIHKLPSVLVLQLKRFE-HLLNGSNRKLDDFIEFPTYLNMKNYC 392
            + ++    +LP VL  +L RFE +   G   K+ + +EFP  L +  Y 
Sbjct: 358 KSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYM 407



 Score = 38.9 bits (89), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 409 IIYELIGIVSHKGTVNEGHYIAFC-KISGGQWFKFNDSMVSSISQEEVLKE 458
           + Y L  ++ H+G  N GHY A+       +W K+ND  V+  S EE++++
Sbjct: 591 VPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRD 641


>3C5K-A nrPDB
          Length = 109

 Score = 34.7 bits (78), Expect = 0.10,   Method: Composition-based stats.
 Identities = 24/92 (26%), Positives = 43/92 (46%), Gaps = 7/92 (7%)

Query: 35  VPKEKFLNTMKCGTCHEINSGATFMCLQCG--FCGCWNHSHFLSHSKQIGHIFGINSNNG 92
           +P      T  CG C  I     ++CL C   +CG + + H L H    GH   ++  + 
Sbjct: 16  IPAAGLDVTQPCGDCGTIQE--NWVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDL 73

Query: 93  LLFCFKCEDYIGN---IDLINDAILAKYWDDV 121
             +C+ C+ Y+ +   +D+ N A   K+ +D+
Sbjct: 74  SAWCYYCQAYVHHQALLDVKNIAHQNKFGEDM 105


>5G0F-A nrPDB
          Length = 110

 Score = 33.9 bits (76), Expect = 0.18,   Method: Composition-based stats.
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 3/60 (5%)

Query: 49  CHEINSGA-TFMCLQCG--FCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGN 105
           C E    A  ++CL C    CG + + H ++H ++ GH   ++  +  ++C+ CE Y+ N
Sbjct: 28  CEECGGEAENWICLFCYKVLCGRYVNQHMVTHGQESGHPVVLSFADLSVWCYACESYVHN 87


>1NI3-A nrPDB
          Length = 392

 Score = 33.5 bits (75), Expect = 0.19,   Method: Compositional matrix adjust.
 Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 2/56 (3%)

Query: 128 PSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCF 183
           P    + G+ G+ N+G + F  +I + ++ NP    +  + I     KV  PD+ F
Sbjct: 17  PGNNLKTGIVGMPNVGKSTFFRAITKSVLGNP--ANYPYATIDPEEAKVAVPDERF 70


>2PVP-A nrPDB
          Length = 367

 Score = 32.3 bits (72), Expect = 0.41,   Method: Compositional matrix adjust.
 Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 1/45 (2%)

Query: 421 GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQ-AYLLF 464
           G V  G ++ FC + GG  F+   S+VS+I+ + VLK++  Y +F
Sbjct: 13  GLVPRGSHMEFCVLFGGASFEHEISIVSAIALKGVLKDRIKYFIF 57


>5WLC-LP nrPDB
          Length = 440

 Score = 28.9 bits (63), Expect = 4.7,   Method: Compositional matrix adjust.
 Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 334 YHCGECNSTQDAIKQLGIHKLPSVLVLQLKR--FEHLLNGSNRKLDDFIEFPTYLNMKNY 391
           Y+  +C    D + + G+     V ++  KR  FEH LN     ++D+I++  Y +  N 
Sbjct: 6   YYLEQCIPEMDDLVEKGLFTKNEVSLIMKKRTDFEHRLNSRGSSINDYIKYINYESNVNK 65

Query: 392 CSTKEKDKHSENGKVPDI----IYELIGIVSHKGT 422
              K   +  +  K   +    I + IG +  +GT
Sbjct: 66  LRAKRCKRILQVKKTNSLSDWSIQQRIGFIYQRGT 100


>3AXH-A nrPDB
          Length = 589

 Score = 28.1 bits (61), Expect = 8.3,   Method: Compositional matrix adjust.
 Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 13/122 (10%)

Query: 353 KLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPT--YLNMK---NYCSTKEKDKHSENGKVP 407
           KL SVL+  L    ++  G      +F  +P   Y +++   NY + KE+  H EN +  
Sbjct: 373 KLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEE--HGENSEEM 430

Query: 408 DIIYELIGIVS--HKGTV----NEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAY 461
               E I ++S  H  T      E     F   S   WF  NDS    I+ E+ +K+   
Sbjct: 431 KKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNS 490

Query: 462 LL 463
           +L
Sbjct: 491 VL 492


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

4FIP-A nrPDB                                                          677   0.0  
2Y6E-A nrPDB                                                          326   1e-89
6CPM-C nrPDB                                                          304   9e-83
3JCR-V nrPDB                                                          300   9e-82
5GJQ-x nrPDB                                                          297   6e-81
6DGF-A nrPDB                                                          291   5e-79
2GFO-A nrPDB                                                          287   1e-77
3MTN-A nrPDB                                                          285   2e-77
5L8W-A nrPDB                                                          283   1e-76
5K1A-A nrPDB                                                          282   3e-76
5L8H-A nrPDB                                                          280   1e-75
5OHN-A nrPDB                                                          279   1e-75
5OHK-A nrPDB                                                          274   7e-74
5GVI-A nrPDB                                                          270   8e-73
2AYN-A nrPDB                                                          268   3e-72
6HEH-A nrPDB                                                          265   3e-71
5CHV-A nrPDB                                                          247   9e-66
5WCH-A nrPDB                                                          243   2e-64
2F1Z-A nrPDB                                                          241   5e-64
5J7T-A nrPDB                                                          238   4e-63
5JTJ-A nrPDB                                                          238   5e-63
5JTV-A nrPDB                                                          236   1e-62
5TXK-A nrPDB                                                          216   2e-56
6H4H-A nrPDB                                                          201   6e-52
6H4J-A nrPDB                                                          197   1e-50
3IHP-A nrPDB                                                          193   2e-49
5MPC-8 nrPDB                                                          117   1e-26
1VJV-A nrPDB                                                          110   2e-24

Sequences not found previously or not previously below threshold:

5O71-A nrPDB                                                          198   3e-51
4MSX-A nrPDB                                                           76   2e-14
3WXF-A nrPDB                                                           39   0.004
3C5K-A nrPDB                                                           37   0.017
2VHF-A nrPDB                                                           36   0.038
3BYN-A nrPDB                                                           34   0.12 
3OM6-A nrPDB                                                           34   0.15 
2UZG-A nrPDB                                                           34   0.15 
3LNB-A nrPDB                                                           30   2.3  
2I50-A nrPDB                                                           30   2.7  
2IO3-A nrPDB                                                           30   3.1  
4WUR-A nrPDB                                                           29   6.6  
5KO3-A nrPDB                                                           28   7.6  

>4FIP-A nrPDB
          Length = 476

 Score =  677 bits (1746), Expect = 0.0,   Method: Composition-based stats.
 Identities = 470/471 (99%), Positives = 471/471 (100%)

Query: 1   MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMC 60
           MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMC
Sbjct: 6   MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMC 65

Query: 61  LQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDD 120
           LQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDD
Sbjct: 66  LQCGFCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDD 125

Query: 121 VCTKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPD 180
           VCTKTMVPSMERRDGLSGLINMG+TCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPD
Sbjct: 126 VCTKTMVPSMERRDGLSGLINMGNTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPD 185

Query: 181 KCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHE 240
           KCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHE
Sbjct: 186 KCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHE 245

Query: 241 FWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTI 300
           FWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTI
Sbjct: 246 FWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTI 305

Query: 301 DPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVL 360
           DPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVL
Sbjct: 306 DPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVL 365

Query: 361 QLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHK 420
           QLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHK
Sbjct: 366 QLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHK 425

Query: 421 GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN 471
           GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN
Sbjct: 426 GTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQVN 476


>2Y6E-A nrPDB
          Length = 367

 Score =  326 bits (835), Expect = 1e-89,   Method: Composition-based stats.
 Identities = 102/378 (26%), Positives = 164/378 (43%), Gaps = 58/378 (15%)

Query: 129 SMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALD 188
            M  + GL GL N+G+TCFM+S LQCL +      + +   +       +P       + 
Sbjct: 1   GMHIQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNP-----LGMK 55

Query: 189 KIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQ 248
             + E Y  L  +  S        +       T   +     +GY QQD+ E   F+++ 
Sbjct: 56  GEIAEAYAELIKQMWSGRDAHVAPRM----FKTQVGRFAPQFSGYQQQDSQELLAFLLDG 111

Query: 249 IHQSY----------------VLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGC 292
           +H+                    D   AKE    +  + + ++   F G  +S++VCP C
Sbjct: 112 LHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPEC 171

Query: 293 QNNSKTTIDPFLDLSLDIKDKK-------------------KLYECLDSFHKKEQLKDFN 333
              S  T DPF  L+L +  KK                    L +C++ F   E L + +
Sbjct: 172 AKVS-VTFDPFCYLTLPLPLKKDRVMEGPMLQPQKKKKTTVALRDCIELFTTMETLGEHD 230

Query: 334 -YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTY-LNMKNY 391
            ++C  C   Q A K+  +  LP +LV+ LKRF +     + KLD  +EFP   LNM  +
Sbjct: 231 PWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRD-KLDTVVEFPIRGLNMSEF 289

Query: 392 CSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKIS-GGQWFKFNDSMVSSI 450
                      N      +Y+LI + +H G +  GHY A+ K    G+W+ F+DS VS  
Sbjct: 290 VC---------NLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLA 340

Query: 451 SQEEVLKEQAYLLFYTIR 468
           S+++++ + AY+LFY  R
Sbjct: 341 SEDQIVTKAAYVLFYQRR 358


>6CPM-C nrPDB
          Length = 349

 Score =  304 bits (777), Expect = 9e-83,   Method: Composition-based stats.
 Identities = 105/359 (29%), Positives = 167/359 (46%), Gaps = 52/359 (14%)

Query: 133 RDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVH 192
           + GL GL N+G+TCFM+S +QCL + P    + ++  +       +P       +   + 
Sbjct: 16  QPGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNP-----LGMRGEIA 70

Query: 193 ELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS 252
           + Y  L  KQ  S   S      F    T   +     +GY QQD  E   F+++ +H+ 
Sbjct: 71  KSYAEL-IKQMWSGKFSYVTPRAF---KTQVGRFAPQFSGYQQQDCQELLAFLLDGLHED 126

Query: 253 Y----------------VLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNS 296
                              D   A+E    + K+ + I+  +F G  +S++VCP C   S
Sbjct: 127 LNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKIS 186

Query: 297 KTTIDPFLDLSLDIKDKK----KLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGI 351
             T DPF  L+L +   K    KL +C++ F  KE+L  +  ++C  C   Q A K+L +
Sbjct: 187 -VTFDPFCYLTLPLPMPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDL 245

Query: 352 HKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDII 410
             LP VLV+ LKRF +     + KLD  ++FP   L+M                      
Sbjct: 246 WSLPPVLVVHLKRFSYSRYMRD-KLDTLVDFPINDLDMSG------------------CR 286

Query: 411 YELIGIVSHKGTVNEGHYIAFCKIS-GGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIR 468
           Y LI + +H G +  GHY AF K    G+W+ F+DS VS+ S+++++ + AY+LFY  +
Sbjct: 287 YNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQ 345


>3JCR-V nrPDB
          Length = 565

 Score =  300 bits (768), Expect = 9e-82,   Method: Composition-based stats.
 Identities = 93/462 (20%), Positives = 173/462 (37%), Gaps = 89/462 (19%)

Query: 57  TFMCLQCG--FCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYIGNIDLINDAI- 113
            + CL CG  F G    SH   HS Q  H   +N +    +C        N ++I+ ++ 
Sbjct: 133 AYACLVCGKYFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLP-----DNYEIIDSSLE 187

Query: 114 -LAKYWDDVCTKTMVPSMERR-------------DGLSGLINMGSTCFMSSILQCLIHNP 159
            +        TK  + +++++              G+ GL N+ +  + +++LQ L + P
Sbjct: 188 DITYVLKPTFTKQQIANLDKQAKLSRAYDGTTYLPGIVGLNNIKANDYANAVLQALSNVP 247

Query: 160 YFIRHSMSQIHSNNCKVRSPDKCFSCA--LDKIVHELYGALNTKQASSSSTSTNRQTGFI 217
               + + + +  N K    D  F       +++ +L+   N K   S            
Sbjct: 248 PLRNYFLEEDNYKNIKRPPGDIMFLLVQRFGELMRKLWNPRNFKAHVSPHEMLQA----- 302

Query: 218 YLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHT 277
            ++ C+ K  Q      Q D  +F  + +N +H +                   + IV  
Sbjct: 303 -VVLCSKKTFQIT---KQGDGVDFLSWFLNALHSALGGTKKK-----------KKTIVTD 347

Query: 278 VFEGS---LESSIVCPGCQNNSKTT------------IDPFLDLSLDIK------DKKK- 315
           VF+GS       +  P      K                 F+ L+LD+       D+K+ 
Sbjct: 348 VFQGSMRIFTKKLPHPDLPAEEKEQLLHNDEYQETMVESTFMYLTLDLPTAPLYKDEKEQ 407

Query: 316 -------LYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHL 368
                  L+  L  F+   + +   Y        ++ +K+  + KLP  L+  +KRF   
Sbjct: 408 LIIPQVPLFNILAKFNGITEKEYKTY-------KENFLKRFQLTKLPPYLIFCIKRFTKN 460

Query: 369 LNGSNRKLDDFIEFP-TYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGH 427
            N    K    + FP T ++++ Y S + +  H       +  Y+LI  + H G  +EG 
Sbjct: 461 -NFFVEKNPTIVNFPITNVDLREYLSEEVQAVHK------NTTYDLIANIVHDGKPSEGS 513

Query: 428 Y-IAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIR 468
           Y I       G+W++  D  V+ I  + +   +AY+  +  R
Sbjct: 514 YRIHVLHHGTGKWYELQDLQVTDILPQMITLSEAYIQIWKRR 555


>5GJQ-x nrPDB
          Length = 494

 Score =  297 bits (761), Expect = 6e-81,   Method: Composition-based stats.
 Identities = 97/444 (21%), Positives = 179/444 (40%), Gaps = 77/444 (17%)

Query: 87  INSNNGLLFCFKCEDYIGNIDLINDAILAK--YWDDVCTKTMVPSMERRDGLSGLINMGS 144
           I   NG+         +G+ D + +   AK  + +D+  + +  +ME      GL N+G+
Sbjct: 61  IKIKNGMTLLM-----MGSADALPEEPSAKTVFVEDMTEEQLASAMELP---CGLTNLGN 112

Query: 145 TCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQAS 204
           TC+M++ +QC+   P   + ++ +       +R+  +  S     I   L    ++   +
Sbjct: 113 TCYMNATVQCIRSVPEL-KDALKRYAG---ALRASGEMASAQY--ITAALRDLFDSMDKT 166

Query: 205 SSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY-VLDLPNAKEV 263
           SSS        F+++    +        Y QQDA+E W  ++  + Q    ++  + KE 
Sbjct: 167 SSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKET 226

Query: 264 S-----RANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTT-IDPFLDLSLDIKDK-KKL 316
                  A   + + ++   F    E+++ C   +    T   +  L LS  I  + K L
Sbjct: 227 DSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL 286

Query: 317 YECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGS-NRK 375
           +  L    ++E  K               IK   I +LP+ L +Q+ RF +    S N K
Sbjct: 287 FTGLKLRLQEEITK----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAK 342

Query: 376 LDDFIEFPTYLNMKNYC---------STKEKDKHSENGKVPDI----------------- 409
           +   ++FP  L+M   C         S + K K  E+ KV                    
Sbjct: 343 VLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYE 402

Query: 410 --------------IYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEE 454
                          Y+L  +++H+G + + GHY+++ K    +W KF+D  VS ++ E+
Sbjct: 403 PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPED 462

Query: 455 VLKEQ-------AYLLFYTIRQVN 471
           +L+         AY+L Y  R+V 
Sbjct: 463 ILRLSGGGDWHIAYVLLYGPRRVE 486


>6DGF-A nrPDB
          Length = 370

 Score =  291 bits (744), Expect = 5e-79,   Method: Composition-based stats.
 Identities = 105/356 (29%), Positives = 161/356 (45%), Gaps = 45/356 (12%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           GL+GL N+G+TCFM+SILQCL +      + + +++  +          S A   +V E 
Sbjct: 30  GLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDL------HHGSNAHTALVEEF 83

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQ--- 251
              + T   SS     N         T   +      GY+QQDA EF +F+++ +H    
Sbjct: 84  AKLIQTIWTSS----PNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVN 139

Query: 252 -------------SYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT 298
                         ++ D    +++ R   ++ +  +  +F G L+SS+ C  C   S T
Sbjct: 140 RVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCS-T 198

Query: 299 TIDPFLDLSLDIKDKK----KLYECLDSFHKKEQLK-DFNYHCGECNSTQDAIKQLGIHK 353
             DPF DLSL I  +      L +C+  F K++ L  D    C  C   +  IK+  I +
Sbjct: 199 VFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQR 258

Query: 354 LPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDIIYE 412
            P +LVL LKRF         KL  F+ FP   L+++ + S                +Y 
Sbjct: 259 FPKILVLHLKRFS-ESRIRTSKLTTFVNFPLRDLDLREFASENTNHA----------VYN 307

Query: 413 LIGIVSHKGTVNEGHYIAFCK-ISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTI 467
           L  + +H GT   GHY A+C+    G+W  FNDS V+ +S  +V    AYLLFY +
Sbjct: 308 LYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYEL 363


>2GFO-A nrPDB
          Length = 396

 Score =  287 bits (733), Expect = 1e-77,   Method: Composition-based stats.
 Identities = 110/359 (30%), Positives = 174/359 (48%), Gaps = 49/359 (13%)

Query: 134 DGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHE 193
             L+GL N+G+TC+M+SILQCL + P+     ++   + NC     ++         V E
Sbjct: 60  PALTGLRNLGNTCYMNSILQCLCNAPH-----LADYFNRNCYQDDINRSNLLGHKGEVAE 114

Query: 194 LYG----ALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQI 249
            +G    AL T Q    S    + T          KIN   AGYSQQD+ E   F+++ +
Sbjct: 115 EFGIIMKALWTGQYRYISPKDFKIT--------IGKINDQFAGYSQQDSQELLLFLMDGL 166

Query: 250 HQ----------------SYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQ 293
           H+                 ++ D   A+   + + +  E I+  +F+G  +S++ C  C 
Sbjct: 167 HEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCH 226

Query: 294 NNSKTTIDPFLDLSLDIKDKK--KLYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLG 350
             S  T + F+ LSL +       L +CL  F K+E+L D N ++C  C + +D++K++ 
Sbjct: 227 KKS-RTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIE 285

Query: 351 IHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTY-LNMKNYCSTKEKDKHSENGKVPDI 409
           I KLP VL++ LKRF +      +KL   ++FP   L++  Y    + +           
Sbjct: 286 IWKLPPVLLVHLKRFSYDGRWK-QKLQTSVDFPLENLDLSQYVIGPKNNLKK-------- 336

Query: 410 IYELIGIVSHKGTVNEGHYIAFCKISGGQ-WFKFNDSMVSSISQEEVLKEQAYLLFYTI 467
            Y L  + +H G ++ GHY A+CK +  Q WFKF+D  VS IS   V    AY+LFYT 
Sbjct: 337 -YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTS 394


>3MTN-A nrPDB
          Length = 373

 Score =  285 bits (729), Expect = 2e-77,   Method: Composition-based stats.
 Identities = 98/374 (26%), Positives = 163/374 (43%), Gaps = 63/374 (16%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GL N+G+TCF++++LQCL          + +          P    +  L +   ++
Sbjct: 21  GHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEV----PGGGRAQELTEAFADV 76

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIH---- 250
            GAL    +  +   T  +  F        K   + +GYSQQDA EF + ++ ++H    
Sbjct: 77  IGALWHPDSCEAVNPTRFRAVF-------QKYVPSFSGYSQQDAQEFLKLLMERLHLEIN 129

Query: 251 ---------------------------QSYVLDLPNAKEVSRANNKQCECIVHTVFEGSL 283
                                      +  + D   A  + +   ++ +  +  +F G L
Sbjct: 130 RRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQL 189

Query: 284 ESSIVCPGCQNNSKTTIDPFLDLSLDIKDKK------KLYECLDSFHKKEQLKDFNYH-C 336
           +S + C  C   S TT + F DLSL I  K        L +C + F K+E+L+  N   C
Sbjct: 190 KSCLKCQACGYRS-TTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVC 248

Query: 337 GECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFP-TYLNMKNYCSTK 395
             C     + K+L + + P +LVL L RF     GS +K    ++FP   L++ ++ S K
Sbjct: 249 DRCRQKTRSTKKLTVQRFPRILVLHLNRFSASR-GSIKKSSVGVDFPLQRLSLGDFASDK 307

Query: 396 EKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEV 455
                         +Y+L  + +H G+V+ GHY A C+   G W  +NDS VS +S+ +V
Sbjct: 308 AGSP----------VYQLYALCNHSGSVHYGHYTALCRCQTG-WHVYNDSRVSPVSENQV 356

Query: 456 LKEQAYLLFYTIRQ 469
              + Y+LFY + Q
Sbjct: 357 ASSEGYVLFYQLMQ 370


>5L8W-A nrPDB
          Length = 376

 Score =  283 bits (724), Expect = 1e-76,   Method: Composition-based stats.
 Identities = 103/358 (28%), Positives = 162/358 (45%), Gaps = 51/358 (14%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELY 195
             GL+N G+TC+ +S+LQ L    YF R    ++ +   + R  +   +C     + +L+
Sbjct: 44  YFGLVNFGNTCYCNSVLQAL----YFCRPFREKVLAYKSQPRKKESLLTC-----LADLF 94

Query: 196 GALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVL 255
            ++ T++         +       +T   K N+    Y QQDAHEF  +++N I      
Sbjct: 95  HSIATQKKKVGVIPPKK------FITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQE 148

Query: 256 DLPNAKEVSR----------ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLD 305
           +    K+  R           N+      VH +F+G+L +   C  C+  S    D FLD
Sbjct: 149 ERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDED-FLD 207

Query: 306 LSLDIKDKKKLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKR 364
           LS+D++    +  CL  F   E L  ++ Y+C EC S Q+A K++ + KLP +L L LKR
Sbjct: 208 LSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKR 267

Query: 365 FEH-LLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT- 422
           F++        KL   + FP  L + N          S +   PD +Y+L+ +V H G+ 
Sbjct: 268 FKYMDQLHRYTKLSYRVVFPLELRLFN---------TSGDATNPDRMYDLVAVVVHCGSG 318

Query: 423 VNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVL------------KEQAYLLFYTIR 468
            N GHYIA  K S   W  F+D +V  I  + +              E  Y+LFY  R
Sbjct: 319 PNRGHYIAIVK-SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 375


>5K1A-A nrPDB
          Length = 331

 Score =  282 bits (720), Expect = 3e-76,   Method: Composition-based stats.
 Identities = 103/356 (28%), Positives = 162/356 (45%), Gaps = 51/356 (14%)

Query: 138 GLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGA 197
           GL+N G+TC+ +S+LQ L    YF R    ++ +   + R  +   +C     + +L+ +
Sbjct: 1   GLVNFGNTCYCNSVLQAL----YFCRPFREKVLAYKSQPRKKESLLTC-----LADLFHS 51

Query: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDL 257
           + T++         +       +T   K N+    Y QQDAHEF  +++N I      + 
Sbjct: 52  IATQKKKVGVIPPKK------FITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEER 105

Query: 258 PNAKEVSR----------ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLS 307
              K+  R           N+      VH +F+G+L +   C  C+  S    D FLDLS
Sbjct: 106 KQEKQNGRLPNGNIDNENNNSTPDPTWVHEIFQGTLTNETRCLTCETISSKDED-FLDLS 164

Query: 308 LDIKDKKKLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFE 366
           +D++    +  CL  F   E L  ++ Y+C EC S Q+A K++ + KLP +L L LKRF+
Sbjct: 165 VDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFK 224

Query: 367 H-LLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT-VN 424
           +        KL   + FP  L + N          S +   PD +Y+L+ +V H G+  N
Sbjct: 225 YMDQLHRYTKLSYRVVFPLELRLFN---------TSGDATNPDRMYDLVAVVVHCGSGPN 275

Query: 425 EGHYIAFCKISGGQWFKFNDSMVSSISQEEVL------------KEQAYLLFYTIR 468
            GHYIA  K S   W  F+D +V  I  + +              E  Y+LFY  R
Sbjct: 276 RGHYIAIVK-SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSR 330


>5L8H-A nrPDB
          Length = 359

 Score =  280 bits (716), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 100/359 (27%), Positives = 161/359 (44%), Gaps = 51/359 (14%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELY 195
             GL+N G+TC+++S+LQ L    YF R     + +   + +  +   +C     + +L+
Sbjct: 27  YFGLVNFGNTCYVNSVLQAL----YFCRPFRENVLAYKAQQKKKENLLTC-----LADLF 77

Query: 196 GALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVL 255
            ++ T++         +       ++   K N     Y QQDAHEF  +++N I      
Sbjct: 78  HSIATQKKKVGVIPPKK------FISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE 131

Query: 256 DLPNAKEVSR----------ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLD 305
           +    K+  +           NNK     VH +F+G+L +   C  C+  S    D FLD
Sbjct: 132 EKKQEKQNGKLKNGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDED-FLD 190

Query: 306 LSLDIKDKKKLYECLDSFHKKEQL-KDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKR 364
           LS+D++    +  CL  F   E L  +  Y+C  C S Q+A K++ + KLP +L L LKR
Sbjct: 191 LSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILALHLKR 250

Query: 365 FEHLLNGSN-RKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGT- 422
           F+++       KL   + FP  L + N          S +    D +Y+L+ +V H G+ 
Sbjct: 251 FKYMEQLRRYTKLSYRVVFPLELRLFN---------TSSDAVNLDRMYDLVAVVVHCGSG 301

Query: 423 VNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVL------------KEQAYLLFYTIRQ 469
            N GHYI   K S G W  F+D +V  I  + +              E  Y+LFY  R+
Sbjct: 302 PNRGHYITIVK-SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRE 359


>5OHN-A nrPDB
          Length = 370

 Score =  279 bits (714), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 93/384 (24%), Positives = 150/384 (39%), Gaps = 72/384 (18%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIRH--SMSQIHSNNCKVRSPDKCFSCALDKIVHE 193
           + GL+N+G+TCFM+S+LQ L   P FIR     +  +S + K   P   +       + +
Sbjct: 6   VPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQK-EPPSHQYLSLTLLHLLK 64

Query: 194 LYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS- 252
                   Q  +     +       L    W+I    + + +QDAHE +  I + +    
Sbjct: 65  ALSC----QEVTDDEVLDASCLLDVLRMYRWQI----SSFEEQDAHELFHVITSSLEDER 116

Query: 253 -------YVLDLPNAKEVSRANNKQCECIV-------------HTVFEGSLESSIVCPGC 292
                  ++ D+ + ++ S    KQ  C                  F G L S++VC  C
Sbjct: 117 DRQPRVTHLFDVHSLEQQSEITPKQITCRTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHC 176

Query: 293 QNNSKTTIDPFLDLSLDIKDKK-----KLYECLDSFHKKEQLKDFNYHCGECNSTQD--- 344
           ++ S    D F  LSL I          L  CL  F   E ++D    C  C   +    
Sbjct: 177 EHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVV--CDNCTKIEAKGT 234

Query: 345 ------------AIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYC 392
                        +KQL + KLP  L + L+R     +G+  K  + ++F   L+M  Y 
Sbjct: 235 LNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEDLDMDEY- 293

Query: 393 STKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFCKIS---------GGQWFKFN 443
                 K+  N      ++ L+ +V H G ++ GH++ + +             QW   +
Sbjct: 294 ------KYHSNAST--YLFRLMAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVS 345

Query: 444 DSMVSSISQEEVLKEQAYLLFYTI 467
           D  V   S +EVL   AYLLFY  
Sbjct: 346 DDTVRKASLQEVLSSSAYLLFYER 369


>5OHK-A nrPDB
          Length = 336

 Score =  274 bits (700), Expect = 7e-74,   Method: Composition-based stats.
 Identities = 90/363 (24%), Positives = 145/363 (39%), Gaps = 64/363 (17%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIRH--SMSQIHSNNCKVRSPDKCFSCALDKIVHE 193
           + GL+N+G+TCFM+S+LQ L   P FIR     +  +S + K   P   +       + +
Sbjct: 6   VPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQK-EPPSHQYLSLTLLHLLK 64

Query: 194 LYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY 253
                   Q  +     +       L    W+I    + + +QDAHE +  I + +    
Sbjct: 65  ALSC----QEVTDDEVLDASCLLDVLRMYRWQI----SSFEEQDAHELFHVITSSLEDE- 115

Query: 254 VLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDK 313
                  ++ S ++ K         F G L S++VC  C++ S    D F  LSL I   
Sbjct: 116 -------RDGSGSHWKS-----QHPFHGRLTSNMVCKHCEHQSPVRFDTFDSLSLSIPAA 163

Query: 314 K-----KLYECLDSFHKKEQLKDFNYHCGECNSTQD---------------AIKQLGIHK 353
                  L  CL  F   E ++D    C  C   +                 +KQL + K
Sbjct: 164 TWGHPLTLDHCLHHFISSESVRDVV--CDNCTKIEAKGTLNGEKVEHQRTTFVKQLKLGK 221

Query: 354 LPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYEL 413
           LP  L + L+R     +G+  K  + ++F   L+M  Y       K+  N      ++ L
Sbjct: 222 LPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEDLSMDEY-------KYHSNAST--YLFRL 272

Query: 414 IGIVSHKGTVNEGHYIAFCKIS---------GGQWFKFNDSMVSSISQEEVLKEQAYLLF 464
           + +V H G ++ GH++ + +             QW   +D  V   S +EVL   AYLLF
Sbjct: 273 MAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDTVRKASLQEVLSSSAYLLF 332

Query: 465 YTI 467
           Y  
Sbjct: 333 YER 335


>5GVI-A nrPDB
          Length = 444

 Score =  270 bits (690), Expect = 8e-73,   Method: Composition-based stats.
 Identities = 99/440 (22%), Positives = 155/440 (35%), Gaps = 115/440 (26%)

Query: 136 LSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELY 195
           + GL+N+G+T FM+S+LQ L   P FIR  +    S N   R   +     L + + +L 
Sbjct: 6   VPGLLNLGNTAFMNSLLQGLAACPSFIRW-LEDFTSQNSADRERTE-RETQLSRSLMQLL 63

Query: 196 GALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQ---- 251
            AL     SS     +       LL        +++ + +QDAHE +  + + + +    
Sbjct: 64  KAL-----SSHVPGEDDVLDAGGLLEALRLYRWHISSFEEQDAHELFHVLTSSLEEEQER 118

Query: 252 ----SYVLDLPNAKEVSRANNKQCECI-------------VHTVFEGSLESSIVCPGCQN 294
               +++ D+   ++   +  K   C                  F G L S + C  C+ 
Sbjct: 119 QPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHPIPSLWRTRHPFHGRLTSYMACKRCEQ 178

Query: 295 NSKTTIDPFLDLSLDIKDKK-----KLYECLDSFHKKEQLKDFNYHCGECNSTQD----- 344
            S    D F  LSL I   +      L +CL  F   E +K+    C  C   Q      
Sbjct: 179 QSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKE--VECENCTKQQAGELVN 236

Query: 345 ----------AIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNY--- 391
                      +KQL + KLP  L + L+R      GS  K  + ++F  YL++  Y   
Sbjct: 237 GEVLESQRTTFVKQLKLGKLPQCLCIHLQRLTWSKEGSPIKRQEHVQFTEYLSLDRYKHC 296

Query: 392 ----------------CSTKEKDKHSENG------------------------------- 404
                            S   KDK   NG                               
Sbjct: 297 SAAQSQQKTSRTNKAKASADPKDKAIANGVDSEHCNNNKPQSNGTFPSVFLHSPGLSSQL 356

Query: 405 ------KVPDIIYELIGIVSHKGTVNEGHYIAFCKISGG---------QWFKFNDSMVSS 449
                    + ++ L  ++ H G ++ GH+I + +             QW   +D  V  
Sbjct: 357 NLTYDYSTSEYLFRLTAVLVHHGDMHSGHFITYRRCPAAPRGTSPFSSQWLWVSDDSVRK 416

Query: 450 ISQEEVLKEQAYLLFYTIRQ 469
            S +EVL   AYLLFY   Q
Sbjct: 417 ASLQEVLSSSAYLLFYERMQ 436


>2AYN-A nrPDB
          Length = 404

 Score =  268 bits (685), Expect = 3e-72,   Method: Composition-based stats.
 Identities = 90/409 (22%), Positives = 165/409 (40%), Gaps = 70/409 (17%)

Query: 120 DVCTKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSP 179
           D+  + +  +ME      GL N+G+TC+M++ +QC+   P   + ++ +       +R+ 
Sbjct: 1   DMTEEQLASAMELP---CGLTNLGNTCYMNATVQCIRSVPEL-KDALKRYAG---ALRAS 53

Query: 180 DKCFSCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAH 239
            +  S     I   L    ++   +SSS        F+++    +        Y QQDA+
Sbjct: 54  GEMASAQY--ITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDAN 111

Query: 240 EFWQFIINQIHQSY-VLDLPNAKEVS-----RANNKQCECIVHTVFEGSLESSIVCPGCQ 293
           E W  ++  + Q    ++  + KE        A   + + ++   F    E+++ C   +
Sbjct: 112 ECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESE 171

Query: 294 NNSKTT-IDPFLDLSLDIKDK-KKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGI 351
               T   +  L LS  I  + K L+  L    ++E  K               IK   I
Sbjct: 172 EEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK----QSPTLQRNALYIKSSKI 227

Query: 352 HKLPSVLVLQLKRFEHLLNGS-NRKLDDFIEFPTYLNMKNYC---------STKEKDKHS 401
            +LP+ L +Q+ RF +    S N K+   ++FP  L+M   C         S + K K  
Sbjct: 228 SRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDL 287

Query: 402 ENGKVPDI-------------------------------IYELIGIVSHKG-TVNEGHYI 429
           E+ KV                                   Y+L  +++H+G + + GHY+
Sbjct: 288 EDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYV 347

Query: 430 AFCKISGGQWFKFNDSMVSSISQEEVLKEQ-------AYLLFYTIRQVN 471
           ++ K    +W KF+D  VS ++ E++L+         AY+L Y  R+V 
Sbjct: 348 SWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 396


>6HEH-A nrPDB
          Length = 382

 Score =  265 bits (677), Expect = 3e-71,   Method: Composition-based stats.
 Identities = 87/351 (24%), Positives = 148/351 (42%), Gaps = 50/351 (14%)

Query: 132 RRDGLS-GLINMGSTCFMSSILQCLIHNPYFIR----HSMSQIHSNNCKVRSPDK--CFS 184
           R DG   GL N+G+TC+ S+++Q L   P F R    +S+ Q    NC+  +  +   F 
Sbjct: 9   RVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFM 68

Query: 185 CALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQF 244
             L  +   + G+ N K    S+         + LL  A++ ++      QQD  EF   
Sbjct: 69  QELQYLFALMMGS-NRKFVDPSAA--------LDLLKGAFRSSEE----QQQDVSEFTHK 115

Query: 245 IINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFL 304
           +++ +  ++ L +      +++ N         +F G+  +  V  G    +    + F 
Sbjct: 116 LLDWLEDAFQLAVNVNSPRNKSENPMV-----QLFYGTFLTEGVREGKPFCNN---ETFG 167

Query: 305 DLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKR 364
              L +   + L ECL+       + + +      + +    ++    KLP VL  +L R
Sbjct: 168 QYPLQVNGYRNLDECLEG-----AMVEGDVELLPSDHSVKYGQERWFTKLPPVLTFELSR 222

Query: 365 FEHLLN-GSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTV 423
           FE   + G   K+ + +EFP  + M  Y         S + +VP   Y L  ++ H+G  
Sbjct: 223 FEFNQSLGQPEKIHNKLEFPQIIYMDRYMY----GSGSGSRQVP---YRLHAVLVHEGQA 275

Query: 424 NEGHYIAFCKISGGQ-WFKFNDSMVSSISQEEVLKE--------QAYLLFY 465
           N GHY A+      Q W K+ND  V+  S EEV ++         AY L Y
Sbjct: 276 NAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAYCLMY 326


>5CHV-A nrPDB
          Length = 323

 Score =  247 bits (630), Expect = 9e-66,   Method: Composition-based stats.
 Identities = 90/355 (25%), Positives = 146/355 (41%), Gaps = 53/355 (14%)

Query: 131 ERRDGLSGLINMGSTCFMSSILQCLIHNPYFI--RHSMSQIHSNNCKVRSPDKCFSCALD 188
           +   GL GL N+G TC ++S+LQ  + N  F      ++   S   + RS        L+
Sbjct: 1   DSPHGLVGLHNIGQTCCLNSLLQVFMMNMDFRMILKRITVPRSAEERKRSVPFQLLLLLE 60

Query: 189 KIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQ 248
           K+        +++Q +   T          L+ C  K N  L  + Q DA + +  I N 
Sbjct: 61  KMQ-------DSRQKAVLPT---------ELVQCLQKYNVPL--FVQHDAAQLYLTIWN- 101

Query: 249 IHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSL 308
           + +  + D    +             +  +F    + S++C GC   S       L LSL
Sbjct: 102 LTKDQITDTDLTER------------LQGLFTIWTQESLICVGCTAESSRR-SKLLTLSL 148

Query: 309 DIKDK-----KKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLK 363
            + DK     K L + L  F + ++L   +  C  C       + L +  LP  L + L 
Sbjct: 149 PLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKTPWKQVLKLTHLPQTLTIHLM 208

Query: 364 RFEHLLNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTV 423
           RF    N    K+   + FP  L+      T+E     +  +  +I YEL  +++H G  
Sbjct: 209 RFSAR-NSRTEKICHSVNFPQSLDFSQVLPTEED--LGDTKEQSEIHYELFAVIAHVGMA 265

Query: 424 NEGHYIAFCKIS-GGQWFKFNDSMVSSISQEEV----------LKEQAYLLFYTI 467
           + GHY A+ +    G+WF FNDS V  ++ ++V           +E AYLL YT 
Sbjct: 266 DFGHYCAYIRNPVDGKWFCFNDSHVCWVTWKDVQCTYGNHRYRWRETAYLLVYTK 320


>5WCH-A nrPDB
          Length = 421

 Score =  243 bits (619), Expect = 2e-64,   Method: Composition-based stats.
 Identities = 94/420 (22%), Positives = 159/420 (37%), Gaps = 100/420 (23%)

Query: 133 RDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSM---------------SQIHSNNCKVR 177
             G  GL N G+TC+M+S++Q L   P      +                +   N   V 
Sbjct: 4   PKGFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVD 63

Query: 178 SPDKCF-----------SCALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWK- 225
             D  F               +       G L   Q      + +R     Y+    WK 
Sbjct: 64  PRDDVFGYPQQFEDKPALSKTEDRAAYNIGVLRHLQVIFGHLAASRLQ--YYVPRGFWKQ 121

Query: 226 ---INQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGS 282
                + +    Q DA EF+  +++ + ++                     ++  V  GS
Sbjct: 122 FRLWGEPVNLREQHDALEFFNSLVDSLDEALKALGH-------------PAMLSKVLGGS 168

Query: 283 LESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFN-YHCGECNS 341
                +C GC +  +   + F  L++DI++ + L + L+ + K + L+  N YHC +CN 
Sbjct: 169 FADQKICQGCPHRYECE-ESFTTLNVDIRNHQNLLDSLEQYVKGDLLEGANAYHCEKCNK 227

Query: 342 TQDAIKQLGIHKLPSVLVLQLKRFEHLLNGS-NRKLDDFIEFPTYLNMKNYCSTK----- 395
             D +K+L I KLP VL +QLKRF++        K +D+ EFP  L+M+ Y         
Sbjct: 228 KVDTVKRLLIKKLPPVLAIQLKRFDYDWERECAIKFNDYFEFPRELDMEPYTVAGVAKLE 287

Query: 396 -----------EKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFC--KISG----GQ 438
                      ++ + SE+       Y L+G++ H G  + GHY ++   +  G     +
Sbjct: 288 GDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSGQASGGHYYSYIIQRNGGDGERNR 347

Query: 439 WFKFNDSMVS--SISQEEVLKEQ----------------------------AYLLFYTIR 468
           W+KF+D  V+   +  +E +K Q                            AY+LFY   
Sbjct: 348 WYKFDDGDVTECKMDDDEEMKNQCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYERM 407


>2F1Z-A nrPDB
          Length = 522

 Score =  241 bits (614), Expect = 5e-64,   Method: Composition-based stats.
 Identities = 98/414 (23%), Positives = 163/414 (39%), Gaps = 64/414 (15%)

Query: 76  SHSKQIGHIFGINSNNGLLFCFKCEDYIGNID--LINDAILAK--YWDDVCTKTMVPSME 131
           S S++I H+F    N+     F     + + +   I+D  +    +        +    +
Sbjct: 111 SFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSK 170

Query: 132 RRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIV 191
           +  G  GL N G+TC+M+S+LQ L     F       ++    +     K    AL ++ 
Sbjct: 171 KHTGYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLALQRVF 226

Query: 192 HELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQ 251
           +EL       Q S     T + T      +  W   + L  + Q D  E  + +++ +  
Sbjct: 227 YEL-------QHSDKPVGTKKLT-----KSFGW---ETLDSFMQHDVQELCRVLLDNVE- 270

Query: 252 SYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIK 311
                       ++      E  +  +F G + S I C      S    D + D+ L IK
Sbjct: 271 ------------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYY-DIQLSIK 317

Query: 312 DKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH-LLN 370
            KK ++E    +   EQL   N +    +  Q+A K +    LP VL LQL RF +    
Sbjct: 318 GKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQT 377

Query: 371 GSNRKLDDFIEFPTYLNMKNYCS-TKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYI 429
             N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + GHY+
Sbjct: 378 DQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGGHYV 428

Query: 430 AFCKISG-GQWFKFNDSMVSSISQEEVLK---------------EQAYLLFYTI 467
            +    G G+W KF+D +VS  ++EE ++                 AY+L Y  
Sbjct: 429 VYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 482


>5J7T-A nrPDB
          Length = 671

 Score =  238 bits (607), Expect = 4e-63,   Method: Composition-based stats.
 Identities = 89/351 (25%), Positives = 141/351 (40%), Gaps = 60/351 (17%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GL N G+TC+M+S+LQ L     F       ++    +     K    AL ++ +EL
Sbjct: 2   GYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYEL 57

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYV 254
                  Q S     T + T      +  W   + L  + Q D  E  + +++ +     
Sbjct: 58  -------QHSDKPVGTKKLTK-----SFGW---ETLDSFMQHDVQELCRVLLDNVE---- 98

Query: 255 LDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKK 314
                    ++      E  +  +F G + S I C      S    D + D+ L IK KK
Sbjct: 99  ---------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYY-DIQLSIKGKK 148

Query: 315 KLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH-LLNGSN 373
            ++E    +   EQL   N +    +  Q+A K +    LP VL LQL RF +      N
Sbjct: 149 NIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQN 208

Query: 374 RKLDDFIEFPTYLNMKNYCS-TKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGHYIAFC 432
            K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + GHY+ + 
Sbjct: 209 IKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGGHYVVYL 259

Query: 433 KISG-GQWFKFNDSMVSSISQEEVLK---------------EQAYLLFYTI 467
              G G+W KF+D +VS  ++EE ++                 AY+L Y  
Sbjct: 260 NPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 310


>5JTJ-A nrPDB
          Length = 387

 Score =  238 bits (606), Expect = 5e-63,   Method: Composition-based stats.
 Identities = 89/357 (24%), Positives = 143/357 (40%), Gaps = 60/357 (16%)

Query: 129 SMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALD 188
             ++  G  GL N G+TC+M+S+LQ L     F       ++    +     K    AL 
Sbjct: 15  GSKKHTGYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLALQ 70

Query: 189 KIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQ 248
           ++ +EL       Q S     T + T      +  W   + L  + Q D  E  + +++ 
Sbjct: 71  RVFYEL-------QHSDKPVGTKKLT-----KSFGW---ETLDSFMQHDVQELCRVLLDN 115

Query: 249 IHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSL 308
           +              ++      E  +  +F G + S I C      S    D + D+ L
Sbjct: 116 VE-------------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYY-DIQL 161

Query: 309 DIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH- 367
            IK KK ++E    +   EQL   N +    +  Q+A K +    LP VL LQL RF + 
Sbjct: 162 SIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYD 221

Query: 368 LLNGSNRKLDDFIEFPTYLNMKNYCS-TKEKDKHSENGKVPDIIYELIGIVSHKGTVNEG 426
                N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + G
Sbjct: 222 PQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGG 272

Query: 427 HYIAFCKISG-GQWFKFNDSMVSSISQEEVLK---------------EQAYLLFYTI 467
           HY+ +    G G+W KF+D +VS  ++EE ++                 AY+L Y  
Sbjct: 273 HYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 329


>5JTV-A nrPDB
          Length = 594

 Score =  236 bits (602), Expect = 1e-62,   Method: Composition-based stats.
 Identities = 89/357 (24%), Positives = 143/357 (40%), Gaps = 60/357 (16%)

Query: 129 SMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALD 188
             ++  G  GL N G+TC+M+S+LQ L     F       ++    +     K    AL 
Sbjct: 15  GSKKHTGYVGLKNQGATCYMNSLLQTLF----FTNQLRKAVYMMPTEGDDSSKSVPLALQ 70

Query: 189 KIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQ 248
           ++ +EL       Q S     T + T      +  W   + L  + Q D  E  + +++ 
Sbjct: 71  RVFYEL-------QHSDKPVGTKKLTK-----SFGW---ETLDSFMQHDVQELCRVLLDN 115

Query: 249 IHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSL 308
           +              ++      E  +  +F G + S I C      S    D + D+ L
Sbjct: 116 VE-------------NKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYY-DIQL 161

Query: 309 DIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEH- 367
            IK KK ++E    +   EQL   N +    +  Q+A K +    LP VL LQL RF + 
Sbjct: 162 SIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYD 221

Query: 368 LLNGSNRKLDDFIEFPTYLNMKNYCS-TKEKDKHSENGKVPDIIYELIGIVSHKGTVNEG 426
                N K++D  EFP  L +  +   T  KD  +         Y L  ++ H G  + G
Sbjct: 222 PQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPAN---------YILHAVLVHSGDNHGG 272

Query: 427 HYIAFCKISG-GQWFKFNDSMVSSISQEEVLK---------------EQAYLLFYTI 467
           HY+ +    G G+W KF+D +VS  ++EE ++                 AY+L Y  
Sbjct: 273 HYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIR 329


>5TXK-A nrPDB
          Length = 372

 Score =  216 bits (549), Expect = 2e-56,   Method: Composition-based stats.
 Identities = 90/372 (24%), Positives = 145/372 (38%), Gaps = 72/372 (19%)

Query: 135 GLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHEL 194
           G  GLIN+G+T +++SILQ L     F RH + ++  NN          S  L   +  L
Sbjct: 17  GKIGLINLGNTSYVNSILQALFMASDF-RHCVLRLTENN----------SQPLMTKLQWL 65

Query: 195 YGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQS-- 252
           +G L   Q  + S            L+ +W      +  +QQD  E+ +++++++H+   
Sbjct: 66  FGFLEHSQRPAISPEN--------FLSASW--TPWFSPGTQQDCSEYLKYLLDRLHEEEK 115

Query: 253 ------YVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDL 306
                   L   ++              V  +F G + + I C  C N S    + F DL
Sbjct: 116 TGTRICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICCLCCLNVSS-REEAFTDL 174

Query: 307 SLDIK-----DKKKLYECLDSFHKKEQLKDFN-YHCGECNSTQDAIKQLGIHKLPSVLVL 360
           SL          + + + ++ F   E+L   N Y+C  C S QDA K + + + P  L+L
Sbjct: 175 SLAFPPPGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQDAEKVVELSQGPCYLIL 234

Query: 361 QLKRFEHL-LNGSNRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSH 419
            L RF         RK+ D +  P  L +               G+  D+   ++     
Sbjct: 235 TLLRFSFDLRTMRRRKILDDVSIPLLLRL---------PLAGGRGQAYDLCSVVVHSGV- 284

Query: 420 KGTVNEGHYIAFCKISG----------------GQWFKFNDSMVSSISQEEVL------- 456
             +   GHY  + +                    QW+ FND+ VS  S E V        
Sbjct: 285 --SSESGHYYCYAREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFP 342

Query: 457 KEQAYLLFYTIR 468
           K+ AY+LFY  R
Sbjct: 343 KDTAYVLFYRQR 354


>6H4H-A nrPDB
          Length = 560

 Score =  201 bits (511), Expect = 6e-52,   Method: Composition-based stats.
 Identities = 61/270 (22%), Positives = 112/270 (41%), Gaps = 34/270 (12%)

Query: 132 RRDGLS-GLINMGSTCFMSSILQCLIHNPYFIR----HSMSQIHSNNCKVRSPDK--CFS 184
           R DG   GL N+G+TC+ S+++Q L   P F R    +S+ Q    NC+  +  +   F 
Sbjct: 9   RVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFM 68

Query: 185 CALDKIVHELYGALNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQF 244
             L  +   + G+ N K    S+         + LL  A++ ++      QQD  EF   
Sbjct: 69  QELQYLFALMMGS-NRKFVDPSAA--------LDLLKGAFRSSEE----QQQDVSEFTHK 115

Query: 245 IINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFL 304
           +++ +  ++ L +      +++ N         +F G+  +  V  G    +    + F 
Sbjct: 116 LLDWLEDAFQLAVNVNSPRNKSENPMV-----QLFYGTFLTEGVREGKPFCNN---ETFG 167

Query: 305 DLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKR 364
              L +   + L ECL+       + + +      + +    ++    KLP VL  +L R
Sbjct: 168 QYPLQVNGYRNLDECLEG-----AMVEGDVELLPSDHSVKYGQERWFTKLPPVLTFELSR 222

Query: 365 FEHLLN-GSNRKLDDFIEFPTYLNMKNYCS 393
           FE   + G   K+ + +EFP  + M  Y  
Sbjct: 223 FEFNQSLGQPEKIHNKLEFPQIIYMDRYMY 252



 Score = 71.3 bits (173), Expect = 8e-13,   Method: Composition-based stats.
 Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 9/64 (14%)

Query: 411 YELIGIVSHKGTVNEGHYIAFCKISGGQ-WFKFNDSMVSSISQEEVLKE--------QAY 461
           Y L  ++ H G  N GHY A+      Q W K+ND  V+  S EEV ++         AY
Sbjct: 437 YRLHAVLVHDGQANAGHYWAYIYNQPRQSWLKYNDISVTESSWEEVERDSYGGLRNVSAY 496

Query: 462 LLFY 465
            L Y
Sbjct: 497 CLMY 500


>5O71-A nrPDB
          Length = 716

 Score =  198 bits (504), Expect = 3e-51,   Method: Composition-based stats.
 Identities = 56/282 (19%), Positives = 115/282 (40%), Gaps = 29/282 (10%)

Query: 115 AKYWDDVCTKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNC 174
            + W D          ++     GL N+G+TC+ S+++Q L +   F R  ++    +N 
Sbjct: 151 TEVWRDSRNPYDRKRQDKAP--VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNA 208

Query: 175 K--VRSPDKCFSCALDKIVHELYGAL-NTKQASSSSTSTNRQTGFIYLLTCAWKINQNLA 231
           +   R+  +  +    + +  L+  L  TK+     +        + +L  A+K N +  
Sbjct: 209 QDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRA------VEILKDAFKSNDS-- 260

Query: 232 GYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPG 291
              QQD  EF   +++ +  ++ +      +  +  N   E     +F G   +  V  G
Sbjct: 261 --QQQDVSEFTHKLLDWLEDAFQMKAEEETDEEKPKNPMVE-----LFYGRFLAVGVLEG 313

Query: 292 CQNNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGI 351
            +  +    + F    L +   K L+ECL++   + +++          ++  + ++   
Sbjct: 314 KKFENT---EMFGQYPLQVNGFKDLHECLEAAMIEGEIES-----LHSENSGKSGQEHWF 365

Query: 352 HKLPSVLVLQLKRFEHLLN-GSNRKLDDFIEFPTYLNMKNYC 392
            +LP VL  +L RFE     G   K+ + +EFP  L +  Y 
Sbjct: 366 TELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYM 407



 Score = 67.5 bits (163), Expect = 1e-11,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 9/73 (12%)

Query: 402 ENGKVPDIIYELIGIVSHKGTVNEGHYIAFC-KISGGQWFKFNDSMVSSISQEEVLKE-- 458
            +  +  + Y L  ++ H+G  N GHY A+       +W K+ND  V+  S EE++++  
Sbjct: 584 SDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSF 643

Query: 459 ------QAYLLFY 465
                  AY L Y
Sbjct: 644 GGYRNASAYCLMY 656


>6H4J-A nrPDB
          Length = 552

 Score =  197 bits (500), Expect = 1e-50,   Method: Composition-based stats.
 Identities = 54/260 (20%), Positives = 110/260 (42%), Gaps = 27/260 (10%)

Query: 137 SGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCK--VRSPDKCFSCALDKIVHEL 194
            GL N+G+TC+ S+++Q L +   F R  ++    +N +   R+  +  +    + +  L
Sbjct: 15  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYL 74

Query: 195 YGAL-NTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSY 253
           +  L  TK+     +        + +L  A+K N +     QQD  EF   +++ +  ++
Sbjct: 75  FALLVGTKRKYVDPSRA------VEILKDAFKSNDS----QQQDVSEFTHKLLDWLEDAF 124

Query: 254 VLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDK 313
            +      +  +  N   E     +F G   +  V  G +  +    + F    L +   
Sbjct: 125 QMKAEEETDEEKPKNPMVE-----LFYGRFLAVGVLEGKKFENT---EMFGQYPLQVNGF 176

Query: 314 KKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLN-GS 372
           K L+ECL++   + +++          ++  + ++    +LP VL  +L RFE     G 
Sbjct: 177 KDLHECLEAAMIEGEIES-----LHSENSGKSGQEHWFTELPPVLTFELSRFEFNQALGR 231

Query: 373 NRKLDDFIEFPTYLNMKNYC 392
             K+ + +EFP  L +  Y 
Sbjct: 232 PEKIHNKLEFPQVLYLDRYM 251



 Score = 66.7 bits (161), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 9/73 (12%)

Query: 402 ENGKVPDIIYELIGIVSHKGTVNEGHYIAFC-KISGGQWFKFNDSMVSSISQEEVLKE-- 458
            +  +  + Y L  ++ H+G  N GHY A+       +W K+ND  V+  S EE++++  
Sbjct: 428 SDKSMIQVPYRLHAVLVHEGQANAGHYWAYIFDHRESRWMKYNDIAVTKSSWEELVRDSF 487

Query: 459 ------QAYLLFY 465
                  AY L Y
Sbjct: 488 GGYRNASAYCLMY 500


>3IHP-A nrPDB
          Length = 854

 Score =  193 bits (489), Expect = 2e-49,   Method: Composition-based stats.
 Identities = 73/322 (22%), Positives = 123/322 (38%), Gaps = 63/322 (19%)

Query: 134 DGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHS--NNCKVRSPDKCFSCALDKIV 191
            G +G+ N+G++C+++S++Q L   P F R  + ++     N     P + FS  + K+ 
Sbjct: 342 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTD-PTQDFSTQVAKLG 400

Query: 192 HELYGALNTKQASSSSTSTNR------QTGFIYLLTCA--WKINQNLAGYSQQDAHEFWQ 243
           H L     +K    S            Q G    +  A   K +   +   QQDA EF+ 
Sbjct: 401 HGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFL 460

Query: 244 FIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT-TIDP 302
            +IN + +       N +     N          VF   +E  I C   +    T  +D 
Sbjct: 461 HLINMVER-------NCRSSENPNE---------VFRFLVEEKIKCLATEKVKYTQRVDY 504

Query: 303 FLDLSLDI--------------------KDKKKLYE----------CLDSFHKKEQLKDF 332
            + L + +                    ++K  L E          CL+++   EQ+ DF
Sbjct: 505 IMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDF 564

Query: 333 NYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYC 392
                +  S   A+K       P  LV+Q+K+F   L+   +KLD  IE P  L++    
Sbjct: 565 WSTALQAKSV--AVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLR 622

Query: 393 STKEKDKHSENGKVPDIIYELI 414
            T  +       ++PDI   L+
Sbjct: 623 GTGLQP---GEEELPDIAPPLV 641



 Score = 49.4 bits (116), Expect = 3e-06,   Method: Composition-based stats.
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 4/58 (6%)

Query: 411 YELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTI 467
           Y+L   +SH G +   GHY+   K   G+W  +ND  V +   E+  K+  Y+ FY  
Sbjct: 797 YQLFAFISHMGTSTMCGHYVCHIK-KEGRWVIYNDQKVCAS--EKPPKDLGYIYFYQR 851


>5MPC-8 nrPDB
          Length = 499

 Score =  117 bits (292), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 71/431 (16%), Positives = 128/431 (29%), Gaps = 107/431 (24%)

Query: 117 YWDDVCTKTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKV 176
           + +D+  +  V    +     G  NMG+TC++++ LQ L          ++   S    V
Sbjct: 91  FIEDLAPEQQVQQFAQLP--VGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQG--V 146

Query: 177 RSPDKCFSCALDKIVHELYGALNTKQ-ASSSSTSTNRQTGFIYLLTCAWKINQNLAG-YS 234
            +          +IV E+       Q  S  S         +      +    +  G Y 
Sbjct: 147 SNSGAQDEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFYK 206

Query: 235 QQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQN 294
           QQDA E +  + + +   +                         F    +++I      N
Sbjct: 207 QQDAEELFTQLFHSMSIVFGDKFSED------------------FRIQFKTTIKDTANDN 248

Query: 295 -NSKTTIDPFLDLSLDIKDKKK-LYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIH 352
             +    +    L   I      +   L     ++  K  +        + +      I 
Sbjct: 249 DITVKENESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEK----KIS 304

Query: 353 KLPSVLVLQLKRFEHLLNGSNR-KLDDFIEFPTYLNM-----KNYCSTKEK--------- 397
           +LP  L +Q  RF    + + + K+   + FP  L++       Y + K K         
Sbjct: 305 RLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVE 364

Query: 398 ----------------DKHSENGKVPDIIYELIGIVS----------------------- 418
                              SEN   P   YE    ++                       
Sbjct: 365 KEKNEKEREIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGE 424

Query: 419 -------------HKGTVN-EGHYIAFCKI--SGGQWFKFNDSMVSSISQEEV------- 455
                        H+G  +  GHY AF +      +W+KFND  VS + +E++       
Sbjct: 425 NPSCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGG 484

Query: 456 LKEQAYLLFYT 466
             + A +L Y 
Sbjct: 485 ESDSALILMYK 495


>1VJV-A nrPDB
          Length = 415

 Score =  110 bits (274), Expect = 2e-24,   Method: Composition-based stats.
 Identities = 70/424 (16%), Positives = 124/424 (29%), Gaps = 107/424 (25%)

Query: 124 KTMVPSMERRDGLSGLINMGSTCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCF 183
           +  V    +     G  NMG+TC++++ LQ L          ++   S    V +     
Sbjct: 14  EQQVQQFAQLP--VGFKNMGNTCYLNATLQALYRVNDLRDMILNYNPSQG--VSNSGAQD 69

Query: 184 SCALDKIVHELYGALNTKQ-ASSSSTSTNRQTGFIYLLTCAWKINQNLAG-YSQQDAHEF 241
                +IV E+       Q  S  S         +      +    +  G Y QQDA E 
Sbjct: 70  EEIHKQIVIEMKRCFENLQNKSFKSVLPVVLLNTLRKCYPQFAERDSQGGFYKQQDAEEL 129

Query: 242 WQFIINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQN-NSKTTI 300
           +  + + +   +                         F    +++I      N  +    
Sbjct: 130 FTQLFHSMSIVFGDKFSED------------------FRIQFKTTIKDTANDNDITVKEN 171

Query: 301 DPFLDLSLDIKDKKK-LYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLV 359
           +    L   I      +   L     ++  K  +        + +      I +LP  L 
Sbjct: 172 ESDSKLQCHISGTTNFMRNGLLEGLNEKIEKRSDLTGANSIYSVEK----KISRLPKFLT 227

Query: 360 LQLKRFEHLLNGSNR-KLDDFIEFPTYLNM-----KNYCSTKEK---------------- 397
           +Q  RF    + + + K+   + FP  L++       Y + K K                
Sbjct: 228 VQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKEKNEKE 287

Query: 398 ---------DKHSENGKVPDIIYELIGIVS------------------------------ 418
                       SEN   P   YE    ++                              
Sbjct: 288 REIKRRKFDPSSSENVMTPREQYETQVALNESEKDQWLEEYKKHFPPNLEKGENPSCVYN 347

Query: 419 ------HKGTVN-EGHYIAFCKI--SGGQWFKFNDSMVSSISQEEV-------LKEQAYL 462
                 H+G  +  GHY AF +      +W+KFND  VS + +E++         + A +
Sbjct: 348 LIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGESDSALI 407

Query: 463 LFYT 466
           L Y 
Sbjct: 408 LMYK 411


>4MSX-A nrPDB
          Length = 482

 Score = 76.4 bits (186), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 64/463 (13%), Positives = 126/463 (27%), Gaps = 105/463 (22%)

Query: 49  CHEINSGATFMCLQCG--FCGCWNHSHFLSHSKQIGHIFGINSNNGLLFCFKCEDYI--- 103
           C  ++    + CL CG  + G    S    HS    H   +N  +   +       I   
Sbjct: 83  CITLSPLNVYCCLVCGHYYQGRHEKSPAFIHSIDENHHVFLNLTSLKFYMLPQNVQILHD 142

Query: 104 GNIDLINDAILAKYWDDVCTKTMVPSMERR----------DGLSGLINMGSTCFMSSILQ 153
           G + L+N    A Y         +    R+          +G  G  N  +  +  S+L 
Sbjct: 143 GEVQLLNSIKFAAY--PTYCPKDLEDFPRQCFDLSNRTYLNGFIGFTNAATYDYAHSVLL 200

Query: 154 CLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQASSSST----- 208
            + H      H +     N  +       F   L   V +++     K   S        
Sbjct: 201 LISHMVPVRDHFLLNHFDNQGE-------FIKRLSICVKKIWSPKLFKHHLSVDDFVSYL 253

Query: 209 ---STNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDLPNAKEVSR 265
                         L   W  N+  +  +        + I+N     +            
Sbjct: 254 KVREGLNLNPIDPRLFLLWLFNKICSSSND------LKSILN-----HSCKGKVKIAKVE 302

Query: 266 ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKLYEC-----L 320
              +  E +   V                     + PF  L+LD+ +     +      L
Sbjct: 303 NKPEASESVTGKVI--------------------VKPFWVLTLDLPEFSPFEDGNSVDDL 342

Query: 321 DSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNR-KLDDF 379
              +  + L  F         +        + +LP  L+    RF+   +   + +    
Sbjct: 343 PQINITKLLTKFTKS-----RSSSTSTVFELTRLPQFLIFHFNRFDRNSDHPVKNRNQTL 397

Query: 380 IEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSH--------KGTVNEG----H 427
           +EF + L                  ++  + Y L   V H         G    G    H
Sbjct: 398 VEFSSEL------------------EILHVKYRLKANVVHVVIKQPSTDGNAFNGDEKSH 439

Query: 428 YIAFCK-ISGGQWFKFNDSMVSSISQEEVLKEQAYLLFYTIRQ 469
           +I         +W + +    +    E +  ++ ++  +  ++
Sbjct: 440 WITQLYDNKSEKWIEIDGINTTEREAELLFLKETFIQVWEKQE 482


>3WXF-A nrPDB
          Length = 312

 Score = 39.4 bits (90), Expect = 0.004,   Method: Composition-based stats.
 Identities = 22/98 (22%), Positives = 36/98 (36%), Gaps = 19/98 (19%)

Query: 349 LGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFP-TYLNMKNYCSTKEKDKHSENGKVP 407
           L   + PS L++Q+ RF       N K+     FP   L++ +       +        P
Sbjct: 164 LKFAEAPSCLIIQMPRFGKDFKMFN-KI-----FPSLELDITDLLDDTPLEGG------P 211

Query: 408 DIIYELIGIVSHKGTVNEGHYIAFCKISGGQ--WFKFN 443
               EL  ++     +   HY+AF K       W  F+
Sbjct: 212 HQQMELFAVLC----IETSHYVAFVKYGSADSAWLFFD 245


>3C5K-A nrPDB
          Length = 109

 Score = 37.1 bits (84), Expect = 0.017,   Method: Composition-based stats.
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 7/92 (7%)

Query: 35  VPKEKFLNTMKCGTCHEINSGATFMCLQCG--FCGCWNHSHFLSHSKQIGHIFGINSNNG 92
           +P      T  CG C  I     ++CL C   +CG + + H L H    GH   ++  + 
Sbjct: 16  IPAAGLDVTQPCGDCGTIQEN--WVCLSCYQVYCGRYINGHMLQHHGNSGHPLVLSYIDL 73

Query: 93  LLFCFKCEDYIGNIDLINDAILA---KYWDDV 121
             +C+ C+ Y+ +  L++   +A   K+ +D+
Sbjct: 74  SAWCYYCQAYVHHQALLDVKNIAHQNKFGEDM 105


>2VHF-A nrPDB
          Length = 374

 Score = 35.9 bits (81), Expect = 0.038,   Method: Composition-based stats.
 Identities = 49/318 (15%), Positives = 102/318 (32%), Gaps = 45/318 (14%)

Query: 144 STCFMSSILQCLIHNPYFIRHSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALNTKQA 203
           ++C++ S L CL      +   + +    N       + +S   + +  E+   L     
Sbjct: 17  NSCYLDSTLFCLFAFSSVLDTVLLRPKEKN-----DVEYYSETQELLRTEIVNPL----R 67

Query: 204 SSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFII-NQIHQSYVLDLPNAKE 262
                   +      +L      +   +   ++D  EF   +  + +    +L + +A +
Sbjct: 68  IYGYVCATKIMKLRKILEKVEAASGFTS--EEKDPEEFLNILFHHILRVEPLLKIRSAGQ 125

Query: 263 VS----------RANNKQCECIVHTVFEGSL-ESSIVCPGCQNNSKTTIDPFLDLSLDIK 311
                         N K     +  + E S   S++      +     +  F     D K
Sbjct: 126 KVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGK---DFK 182

Query: 312 DKKKLYECLDSFHKKEQLKDFNYHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNG 371
             KK++  L+  +  + L+D    C  C        +   +  P +   ++K+F    N 
Sbjct: 183 LFKKIFPSLEL-NITDLLEDTPRQCRICGGLAMYECR-ECYDDPDISAGKIKQFCKTCNT 240

Query: 372 S----NRKLDDFIEFPTYLNMKNYCSTKEKDKHSENGKVPDIIYELIGIVSHKGTVNEGH 427
                 ++L+     P  L           D    +G +P    EL  ++     +   H
Sbjct: 241 QVHLHPKRLNHKYN-PVSL------PKDLPDWDWRHGCIPCQNMELFAVLC----IETSH 289

Query: 428 YIAFCK--ISGGQWFKFN 443
           Y+AF K       W  F+
Sbjct: 290 YVAFVKYGKDDSAWLFFD 307


>3BYN-A nrPDB
          Length = 473

 Score = 34.4 bits (77), Expect = 0.12,   Method: Composition-based stats.
 Identities = 9/30 (30%), Positives = 16/30 (53%)

Query: 436 GGQWFKFNDSMVSSISQEEVLKEQAYLLFY 465
            G+W+ F DS  S ++ + +     Y+L Y
Sbjct: 350 NGKWYLFTDSRGSKMTIDGITSNDIYMLGY 379


>3OM6-A nrPDB
          Length = 456

 Score = 34.0 bits (76), Expect = 0.15,   Method: Composition-based stats.
 Identities = 9/32 (28%), Positives = 18/32 (56%)

Query: 434 ISGGQWFKFNDSMVSSISQEEVLKEQAYLLFY 465
              G+W+ F DS  S ++ + + ++  Y+L Y
Sbjct: 330 KKDGKWYLFTDSRGSKMTIDGIGQDDVYMLGY 361


>2UZG-A nrPDB
          Length = 97

 Score = 34.0 bits (76), Expect = 0.15,   Method: Composition-based stats.
 Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 6/63 (9%)

Query: 47  GTCHE--INSGATFMCLQ--CGFCGCWNHS--HFLSHSKQIGHIFGINSNNGLLFCFKCE 100
           GTC +  +     + CL+  C + GC      H   HS++  H   +N     ++C+ C 
Sbjct: 26  GTCQDCKVQGPNLWACLENRCSYVGCGESQVDHSTIHSQETKHYLTVNLTTLRVWCYACS 85

Query: 101 DYI 103
             +
Sbjct: 86  KEV 88


>3LNB-A nrPDB
          Length = 309

 Score = 30.1 bits (66), Expect = 2.3,   Method: Composition-based stats.
 Identities = 11/29 (37%), Positives = 16/29 (55%)

Query: 38  EKFLNTMKCGTCHEINSGATFMCLQCGFC 66
           EK L   + G C+E+NS   +  + CGF 
Sbjct: 88  EKLLIQKRGGLCYELNSLLYYFLMDCGFQ 116


>2I50-A nrPDB
          Length = 126

 Score = 29.7 bits (65), Expect = 2.7,   Method: Composition-based stats.
 Identities = 14/54 (25%), Positives = 29/54 (53%), Gaps = 6/54 (11%)

Query: 56  ATFMCLQCGFCGCWNHS---HFLSH---SKQIGHIFGINSNNGLLFCFKCEDYI 103
           + ++CL+CG  GC  +S   H L H    +   H   ++ +N  ++C+ C++ +
Sbjct: 53  SVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCDNEV 106


>2IO3-A nrPDB
          Length = 232

 Score = 29.7 bits (65), Expect = 3.1,   Method: Composition-based stats.
 Identities = 25/186 (13%), Positives = 50/186 (26%), Gaps = 16/186 (8%)

Query: 152 LQCLIH----NPYFIRHSMSQIHSNNCKVRSP----------DKCFSCALDKIVHELYGA 197
           +Q L +    N   I   M+ +   N K   P           K  S     +     G 
Sbjct: 45  IQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGV 104

Query: 198 LNTKQASSSSTSTNRQTGFIYLLTCAWKINQNLAGYSQQDAHEFWQFIINQIHQSYVLDL 257
              +Q         +    + ++    K  + L     Q  H   + ++  +        
Sbjct: 105 NLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDS-MGQKGHRICEILLQYLQDESKTKR 163

Query: 258 PNAKEVSR-ANNKQCECIVHTVFEGSLESSIVCPGCQNNSKTTIDPFLDLSLDIKDKKKL 316
            +   +    ++      +     GS      C      S+     F    + +  KK +
Sbjct: 164 NSDLNLLEWTHHSMKPHEIPQQLNGSDSGMFTCKYADYISRDKPITFTQHQMPLFRKKMV 223

Query: 317 YECLDS 322
           +E L  
Sbjct: 224 WEILHQ 229


>4WUR-A nrPDB
          Length = 326

 Score = 28.6 bits (62), Expect = 6.6,   Method: Composition-based stats.
 Identities = 12/56 (21%), Positives = 20/56 (35%), Gaps = 2/56 (3%)

Query: 398 DKHSENGKVPDIIYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQ 452
              +E         + +     +G     GHY+   ++ GG   KF+   VS  S 
Sbjct: 254 GTPNEKLVTTSTAPDFVAFNVFQGIETAVGHYVH-ARLKGGLILKFDSGTVSKTSD 308


>5KO3-A nrPDB
          Length = 257

 Score = 28.2 bits (61), Expect = 7.6,   Method: Composition-based stats.
 Identities = 12/54 (22%), Positives = 20/54 (37%), Gaps = 2/54 (3%)

Query: 400 HSENGKVPDIIYELIGIVSHKG-TVNEGHYIAFCKISGGQWFKFNDSMVSSISQ 452
            +E         + +     +G     GHY+   ++ GG   KF+   VS  S 
Sbjct: 188 PNEKLVTTSTAPDFVAFNVFQGIETAVGHYVH-ARLKGGLILKFDSGTVSKTSD 240


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.312    0.125    0.350 

Lambda     K      H
   0.267   0.0385    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,295,405
Number of Sequences: 36641
Number of extensions: 662137
Number of successful extensions: 1965
Number of sequences better than 10.0: 42
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1592
Number of HSP's gapped (non-prelim): 114
length of query: 471
length of database: 10,336,785
effective HSP length: 101
effective length of query: 370
effective length of database: 6,636,044
effective search space: 2455336280
effective search space used: 2455336280
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.2 bits)