BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P50053 (298 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3NCA-A nrPDB 604 e-173 2HW1-A nrPDB 558 e-160 4LC4-A nrPDB 72 2e-13 3UBO-A nrPDB 69 3e-12 5ZWY-A nrPDB 59 2e-09 2RBC-A nrPDB 57 1e-08 3H49-A nrPDB 56 2e-08 1TYY-A nrPDB 56 2e-08 6ILS-A nrPDB 54 1e-07 2C4E-A nrPDB 52 3e-07 4WJM-A nrPDB 49 2e-06 2QCV-A nrPDB 45 4e-05 1VM7-A nrPDB 43 2e-04 4DU5-A nrPDB 41 6e-04 1V1S-A nrPDB 39 0.002 3BF5-A nrPDB 39 0.002 2QHP-A nrPDB 39 0.003 3RY7-A nrPDB 38 0.004 5C40-A nrPDB 37 0.012 2AA0-A nrPDB 36 0.019 5EYN-A nrPDB 36 0.023 6C9R-A nrPDB 35 0.026 2NWH-A nrPDB 35 0.035 3LOO-A nrPDB 35 0.048 3N1C-A nrPDB 35 0.054 3GBU-A nrPDB 34 0.091 3KD6-A nrPDB 32 0.25 3HJ6-A nrPDB 32 0.26 6CW5-A nrPDB 32 0.28 4GM6-A nrPDB 32 0.28 4US5-D nrPDB 32 0.35 1RK2-A nrPDB 32 0.47 4X8F-A nrPDB 31 0.62 2JG5-A nrPDB 31 0.62 2ABQ-A nrPDB 31 0.67 5KB6-A nrPDB 31 0.74 3KTN-A nrPDB 30 0.94 2DME-A nrPDB 30 1.2 2I5B-A nrPDB 30 1.3 3UQ9-A nrPDB 29 2.3 3LJS-A nrPDB 29 2.6 3IQ0-A nrPDB 29 3.1 3GU2-A nrPDB 28 3.7 3LHX-A nrPDB 28 3.8 3B1N-A nrPDB 27 7.4 5FET-A nrPDB 27 8.6 5EY6-A nrPDB 27 9.4 >3NCA-A nrPDB Length = 313 Score = 604 bits (1557), Expect = e-173, Method: Compositional matrix adjust. Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA Sbjct: 20 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 79 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD 124 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD Sbjct: 80 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD 139 Query: 125 FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG 184 FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG Sbjct: 140 FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG 199 Query: 185 YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA 244 YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA Sbjct: 200 YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA 259 Query: 245 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 298 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV Sbjct: 260 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 313 >2HW1-A nrPDB Length = 298 Score = 558 bits (1439), Expect = e-160, Method: Compositional matrix adjust. Identities = 270/298 (90%), Positives = 281/298 (94%) Query: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM 60 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM Sbjct: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM 60 Query: 61 GSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDV 120 GSMAPGHVADF++ D RR VD+ +Q+ G P + IIN ++G+RTI+ +D SLPDV Sbjct: 61 GSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDV 120 Query: 121 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF Sbjct: 121 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 Query: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL Sbjct: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 Query: 241 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 298 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV Sbjct: 241 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 298 >4LC4-A nrPDB Length = 352 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 82/315 (26%), Positives = 132/315 (41%), Gaps = 38/315 (12%) Query: 1 MEEKQILCVGLVVLDVIS------------------LVDKYPKEDSEIRCLSQRWQRGGN 42 M +L VG ++D+IS L+D E R GG+ Sbjct: 23 MTRFDVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRMGPALEASGGS 82 Query: 43 ASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSC--CI 100 A N+ ++ LG A+ G++A + D D R +GV + KG P + I Sbjct: 83 AGNTAAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGV---HYQTKPKGAFPPTARSMI 139 Query: 101 INNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGR-----NASEQVKMLQRIDA 155 +G R++ + + ++ D E + K + EG A E + RI A Sbjct: 140 FVTEDGERSMNTYLGACVELGPEDVEADVVADAKVTYFEGYLWDPPRAKEAILDCARI-A 198 Query: 156 HNTRQPPEQKIRVSVEVEKPREELFQLFGYG--DVVFVSKDVAKHLGFQSA--EEALRGL 211 H + + S V++ R E L G D+VF ++ A L +Q+ EEAL + Sbjct: 199 HQHGREMSMTLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQEALSL-YQTDDFEEALNRI 257 Query: 212 YGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQG 271 + AV + +E GA L + + +A VVDT GAGD F + ++ +QG Sbjct: 258 AADCKIAAVTM---SENGAVILKGRERY-YVNAIRIREVVDTTGAGDLFASGFLYGYTQG 313 Query: 272 RSVQEALRFGCQVAG 286 RS+++ + GC AG Sbjct: 314 RSLEDCGKLGCLAAG 328 >3UBO-A nrPDB Length = 354 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 77/320 (24%), Positives = 131/320 (40%), Gaps = 34/320 (10%) Query: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEI-------------RCLSQRW-----QRGGN 42 M + +L +G ++D+I+ D E++ I L R GG+ Sbjct: 3 MAKYDVLTIGNAIVDIIARCDDSFLEENGIIKGAMNLINADRAELLYSRMGPAVEASGGS 62 Query: 43 ASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSK---GDTPSS-C 98 A N+ ++ LG A+ G +A + + D R +GV +Q+K G P++ Sbjct: 63 AGNTAAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGVH-----FQTKPLDGHPPTARS 117 Query: 99 CIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGR-----NASEQVKMLQRI 153 I +G R++ + + ++ D E + Q K + EG A + ++ RI Sbjct: 118 MIFVTEDGERSMNTYLGACVELGPEDVEDDVVAQSKVTYFEGYLWDPPRAKDAIREAARI 177 Query: 154 DAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYG 213 AH + + S V + R E +L G V V + + L E+ R L Sbjct: 178 -AHAHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALALYETEDFDRALEL 236 Query: 214 RVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRS 273 R + +EEG+ + + + A +VVDT GAGD + A +F + GRS Sbjct: 237 LARDCKLAAVTLSEEGSVVV-RGAERVRVGASVLEQVVDTTGAGDLYAAGFLFGYTSGRS 295 Query: 274 VQEALRFGCQVAGKKCGLQG 293 ++E + G AG G G Sbjct: 296 LEECSKLGNLAAGIVIGQIG 315 >5ZWY-A nrPDB Length = 349 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 69/291 (23%), Positives = 115/291 (39%), Gaps = 26/291 (8%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 IL VG LD + VD P+ + +S GG +N LGA A + + Sbjct: 38 ILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVGT 97 Query: 66 -GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVL------HDT-SL 117 G +D+ + + R GVD + + K T + +++ + N IV+ H T L Sbjct: 98 DGDGSDY-IKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPEL 156 Query: 118 PDVSATDFEKVDLTQFKWI----HIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173 ++E++ T K++ I + +K + VE Sbjct: 157 LRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQI 216 Query: 174 KPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWA-----EE 228 KP LF +V K +SA A++ L + V+ A E Sbjct: 217 KPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFVLSEN 276 Query: 229 GADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALR 279 GA+ + GK + + VDT GAGD F S+++ +S+GR++ EA + Sbjct: 277 GAEPVHVTGKHV--------KAVDTTGAGDCFVGSMVYFMSRGRNLLEACK 319 >2RBC-A nrPDB Length = 343 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 67/298 (22%), Positives = 115/298 (38%), Gaps = 24/298 (8%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 63 K +LCVG VLD + V PK + ++ G AS++ + +G + G++ Sbjct: 30 KHVLCVGAAVLDTLFRVADMPKGEGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAV 89 Query: 64 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIV-LHDTSLPDVSA 122 ++ D G+D S + + S II+N G R IV +D L + Sbjct: 90 GDDETGTRILRDLSESGIDTSGMTVAPGARSALSTIIIDN-RGERLIVPFYDHRLHEKKR 148 Query: 123 TDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQL 182 + D+ F + ++ R + +L A + + P E L L Sbjct: 149 ACTPE-DIALFDAVLVDVRWPELALDVLTVARALGKPAILDGDV-------APVETLEGL 200 Query: 183 FGYGDVVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVLV------CAWAEEGADALGP 235 + S+ A L G ++ ++ L L+ R + + V C W E Sbjct: 201 APAATHIVFSEPAATRLTGLETVKDMLPVLHARYPQTFIAVTAGPAGCWWTEA------- 253 Query: 236 DGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 D +H VDTL AGD F+ + ++++G + A+R A KC + G Sbjct: 254 DDPTVHFQTTMQVEAVDTLAAGDIFHGTFALAMAEGMQSRAAVRLSSVAAALKCTVFG 311 >3H49-A nrPDB Length = 325 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 68/305 (22%), Positives = 127/305 (41%), Gaps = 36/305 (11%) Query: 1 MEEKQILCVGLVVLDV--------ISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSL 52 ++ ++C+G ++D+ I VD YP E GG+A N T++S Sbjct: 3 LDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLE-------RIAMTTGGDAINEATIISR 55 Query: 53 LGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVL 112 LG A M + F++ R+ +D+ + DT + ++ +G RT V Sbjct: 56 LGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVT-EDGERTFVT 114 Query: 113 H-DTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQV--KMLQRIDAHNTRQPPEQKIRVS 169 + + SL ++ D + +Q K + + S + K L I Q +++ + Sbjct: 115 NRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEI----FTQAKARQMIIC 170 Query: 170 VEVEKPR-----EELFQLFGYGDVVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVLVC 223 ++ KPR +++ + Y D +F + AK L G ++ +E K V+ Sbjct: 171 ADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLACGVKTVVI-- 228 Query: 224 AWAEEGADA--LGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 + G D + + A +DT+GAGD F + I +L +G++++E RF Sbjct: 229 ---KTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNLRECARFA 285 Query: 282 CQVAG 286 A Sbjct: 286 NATAA 290 >1TYY-A nrPDB Length = 339 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 82/310 (26%), Positives = 120/310 (38%), Gaps = 79/310 (25%) Query: 20 VDKYP-KEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRR 78 VD P K++S ++C GG ++N ++ LG C F+G + FL F+ Sbjct: 35 VDLVPEKQNSYLKC------PGGASANVGVCVARLGGECGFIGCLGDDDAGRFLRQVFQD 88 Query: 79 RGVDVSQVAWQSKGDTPSSCCIIN-NSNGNR--TIVLHDTSLPDVSATDFEKVDLTQFKW 135 GVDV+ + + D S+ I+N ++G R T ++H + VS D Q++W Sbjct: 89 NGVDVTFL--RLDADLTSAVLIVNLTADGERSFTYLVHPGADTYVSPQDLPP--FRQYEW 144 Query: 136 IH---------------IEGRNASEQVKMLQRIDAH-------NTRQPPEQKIRVSVEVE 173 + +EG + D + NT + PE R + Sbjct: 145 FYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLRSKMWGNTDEIPELIARSAALAS 204 Query: 174 KPR---EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230 + +EL QL G A H +Q A LR L G Sbjct: 205 ICKVSADELCQLSG-----------ASH--WQDARYYLRDL-----------------GC 234 Query: 231 D----ALGPDGKLLHSDA----FPPPR--VVDTLGAGDTFNASVIFSLSQGRSVQEALRF 280 D +LG DG LL + FP PR VVDT GAGD F ++F+LS+ AL Sbjct: 235 DTTIISLGADGALLITAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLA 294 Query: 281 GCQVAGKKCG 290 CG Sbjct: 295 EAISNANACG 304 >6ILS-A nrPDB Length = 313 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 71/299 (23%), Positives = 122/299 (40%), Gaps = 36/299 (12%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 ++ VG D+ +++ PKE I + + GG +N + L P F+G + Sbjct: 5 LVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGE 64 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIIN-NSNGNRTIVL----HDTSLPDV 120 + G V +S + P+ ++ S+G +I++ + + P++ Sbjct: 65 DAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEI 124 Query: 121 -SATDFEKVD-----LTQFKW---IHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVE 171 S D E V L Q + I+I+ A ++ + +D P ++ S++ Sbjct: 125 MSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLDSID 184 Query: 172 VEKPRE-ELFQLFGYGDVVF--VSKDVAK--HLGFQSAEEALRGLYGRVRKGAVLVCAWA 226 + P E EL +L G F +S+ VAK LG + L KG+ L Sbjct: 185 ILSPNETELSRLTGMPTETFEQISQAVAKCHKLGVKQV------LVKLGSKGSALFIQGE 238 Query: 227 EEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVA 285 K + P +VVDT GAGDTF A+ ++ +G+S +E LRF A Sbjct: 239 -----------KPIQQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAA 286 >2C4E-A nrPDB Length = 302 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/298 (20%), Positives = 125/298 (41%), Gaps = 41/298 (13%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 63 ++I CVG LD I V+K+P+ ++ I+ S R GG A+N+ + LG + + Sbjct: 6 EKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLSCV 65 Query: 64 APGHVADFLVADFRRR----GVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPD 119 DF + + R +++S++ + + +TP + + N T L Sbjct: 66 G----YDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWG----- 116 Query: 120 VSATDFEKVDLTQF--KWIHIEGRNASEQVKMLQRIDAHN-TRQPPEQKIRVSVEVEKPR 176 +A +++++ F + +HI + +K ++ +N P Q + + + Sbjct: 117 -AAKHYKELNPPNFNTEIVHIATGDPEFNLKCAKKAYGNNLVSFDPGQDLP-----QYSK 170 Query: 177 EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALR-GLYGRVRKGAVLVCAWAEEGADALGP 235 E L ++ + + +F++K F+ A L + + + L+ +G+ Sbjct: 171 EMLLEIIEHTNFLFMNKH-----EFERASNLLNFEIDDYLERVDALIVTKGSKGSVIYTK 225 Query: 236 DGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 D K + +V+D GAGD++ A + + +G ++ KCGL G Sbjct: 226 DKK-IEIPCIKAGKVIDPTGAGDSYRAGFLSAYVKGYDLE------------KCGLIG 270 >4WJM-A nrPDB Length = 312 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 69/289 (23%), Positives = 117/289 (40%), Gaps = 34/289 (11%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 ILC G +L+D P+E + Q + GG+ N+ L LG P F ++ Sbjct: 7 MILCCGE------ALIDMLPRETTGGETAFQPFA-GGSVFNTAIALGRLGVPTGFFSGIS 59 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHD--TSLPDVSA 122 D L R VD S A ++ P++ + +G +D T+ +S Sbjct: 60 SDFFGDVLRDTLARSNVDYSFAAISNR---PTTLAFVRLVDGQARYAFYDENTAGRMLSR 116 Query: 123 TDFEKVDLT----QFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVS-VEVEKPR- 176 D VD T F I + + L +A N + IR + + V K Sbjct: 117 NDMPYVDETISAMLFGCISLISEPCGSVYETLLAREAPNRVMFLDPNIRANLITVRKTHL 176 Query: 177 EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 + ++ D+V +S + G + + + + + ++ V++ G Sbjct: 177 TRMKRMIALADIVKLSDEDLDWFGEKGSHDEIAAEWLKLGPKLVVITK---------GAH 227 Query: 237 GKLLHSD--AFPPP----RVVDTLGAGDTFNASVIFSL-SQGRSVQEAL 278 G + +++ P P VVDT+GAGDT NA ++ SL SQG ++AL Sbjct: 228 GAVAYTNHATVPVPGVKVDVVDTVGAGDTVNAGILASLHSQGLLTKDAL 276 >2QCV-A nrPDB Length = 332 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 65/311 (20%), Positives = 127/311 (40%), Gaps = 49/311 (15%) Query: 3 EKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGS 62 E ++ +G +D+ ++ P E++ ++ GG+ +N S LG F+G Sbjct: 11 EFDLIAIGRACIDLNAVEYNRPMEET----MTFSKYVGGSPANIVIGSSKLGLKAGFIGK 66 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKG----------DTPSSCCIINNSNGNRTIVL 112 +A F+ + R GVD S + +G +P C I+ + L Sbjct: 67 IADDQHGRFIESYMRGVGVDTSNLVVDQEGHKTGLAFTEIKSPEECSILMYRQDVADLYL 126 Query: 113 ----------HDTSLPDVSATDFEKVDLTQ--FKWIHIEGRNASEQVKMLQRIDA--HNT 158 + L VS T K + K I + RN VK++ +D ++ Sbjct: 127 SPEEVNEAYIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRN---DVKVVFELDYRPYSW 183 Query: 159 RQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSA----EEALRGLYGR 214 P E + S+ E+ D+V +++ L ++ +E +R L+ Sbjct: 184 ETPEETAVYYSLVAEQ-----------SDIVIGTREEFDVLENRTEKGDNDETIRYLFKH 232 Query: 215 VRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSV 274 + ++V EG+ A G+ A+ +V+ T GAGD++ ++ +++L G+ + Sbjct: 233 SPE--LIVIKHGVEGSFAYTKAGEAYRGYAYKT-KVLKTFGAGDSYASAFLYALISGKGI 289 Query: 275 QEALRFGCQVA 285 + AL++G A Sbjct: 290 ETALKYGSASA 300 >1VM7-A nrPDB Length = 311 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 63/296 (21%), Positives = 115/296 (38%), Gaps = 41/296 (13%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAP-CAFMGSMA 64 I VG +D++ VD + K + + GG +N ++ +G C F+ + Sbjct: 17 ISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIGEKGCRFVTCIG 76 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIIN-NSNGNRTIVLHDTSLPDVSAT 123 +D L+ ++ + G+ + P+ I + G I++ + ++ Sbjct: 77 NDDYSDLLIENYEKLGI-----TGYIRVSLPTGRAFIEVDKTGQNRIIIFPGANAELKKE 131 Query: 124 DFEKVDLTQFKWIHIEGRNASEQ-VKMLQRIDAHNTRQP-PEQKIRVSVEVEKPREELFQ 181 + L++ + ++ E ++ +R + P P Q I EE+FQ Sbjct: 132 LIDWNTLSESDILLLQNEIPFETTLECAKRFNGIVIFDPAPAQGIN---------EEIFQ 182 Query: 182 LFGY-----GDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 Y ++ +SKD F + E+A K ++ LG Sbjct: 183 YLDYLTPNEKEIEALSKDFFGE--FLTVEKAAEKFLELGVKNVIV----------KLGDK 230 Query: 237 GKLL----HSDAFPPPRV--VDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAG 286 G LL FP +V VDT AGD FN + +LS+G++ +EA+ FG A Sbjct: 231 GVLLVNKNEKKHFPTFKVKAVDTTAAGDVFNGAFAVALSEGKNPEEAVIFGTAAAA 286 >4DU5-A nrPDB Length = 336 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 67/311 (21%), Positives = 111/311 (35%), Gaps = 48/311 (15%) Query: 14 LDVIS-------LVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPG 66 LDVI+ LV P +R G +N L+ LG + + Sbjct: 27 LDVITFGEAMMLLVADRPGPLEHAEAFHKR--TAGAETNVAIGLARLGLKVGWASRLGTD 84 Query: 67 HVADFLVADFRRRGVDVSQV--------AWQSKGDTPSSCCIINNSNGNRTIVLHDTSLP 118 + +L+A G+D S V +Q KG + + S+ ++ Sbjct: 85 SMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGK------VTDGSDPPVEYHRKGSAAS 138 Query: 119 DVSATDFEKVDLTQFKWIHIEG---------RNASEQVKMLQRIDAHNTRQPPEQKIRVS 169 + D ++ L + +H G A+ + L R + P + + Sbjct: 139 HMGVADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDPNLRPTLW 198 Query: 170 VEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEG 229 E R+ + L D V + + L ++ E + Y ++ GA LV Sbjct: 199 ATPELMRDAINDLATRADWVLPGMEEGRFLTGETTPEGVARFYRQL--GAKLVVV----- 251 Query: 230 ADALGPDGKLLHSDA-------FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGC 282 LG +G +A FP VVDT+GAGD F VI +L G V EA++ G Sbjct: 252 --KLGAEGAYFDGEAGSGRVAGFPVAEVVDTVGAGDGFAVGVISALLDGLGVPEAVKRGA 309 Query: 283 QVAGKKCGLQG 293 + + + G Sbjct: 310 WIGARAVQVLG 320 >1V1S-A nrPDB Length = 309 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 65/268 (24%), Positives = 104/268 (38%), Gaps = 24/268 (8%) Query: 40 GGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCC 99 GG N L+ LG F+G + + + R GVD++ ++ G T Sbjct: 33 GGAEVNVAVALARLGVKVGFVGRVGEDELGAMVEERLRAEGVDLTHFR-RAPGFTGLYLR 91 Query: 100 IINNSNGNRTIVLHDTSLPDVSATD-FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNT 158 R S A F+ L +++H+ G + + + Sbjct: 92 EYLPLGQGRVFYYRKGSAGSALAPGAFDPDYLEGVRFLHLSGITPALSPEA-RAFSLWAM 150 Query: 159 RQPPEQKIRVSVEV---------EKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALR 209 + + +RVS++V E+ R L + D++F+S++ A+ L F EEALR Sbjct: 151 EEAKRRGVRVSLDVNYRQTLWSPEEARGFLERALPGVDLLFLSEEEAELL-FGRVEEALR 209 Query: 210 GLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLS 269 L +V +GA A DG+ + AF VD +GAGD F A + Sbjct: 210 AL-----SAPEVVLKRGAKGAWAF-VDGRRVEGSAFAV-EAVDPVGAGDAFAAGYLAGAV 262 Query: 270 QGRSVQEALR----FGCQVAGKKCGLQG 293 G V+E LR G VA + +G Sbjct: 263 WGLPVEERLRLANLLGASVAASRGDHEG 290 >3BF5-A nrPDB Length = 306 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 56/285 (19%), Positives = 107/285 (37%), Gaps = 39/285 (13%) Query: 6 ILCVGLVVLDVISLVDKYPKEDS-EIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 + G + +DV+ VD P+E S ++ L R+ GG A N V P ++ Sbjct: 23 LAYFGHLNIDVLISVDSIPREGSVNVKDLRPRF--GGTAGNFAIVAQKFRIPFDLYSAVG 80 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSL----PDV 120 ++L A G++ V + D C I + +H ++ P + Sbjct: 81 MKTHREYL-AMIESMGINTGHV--EKFEDESGPICYIATDGKKQVSFMHQGAMAAWAPQL 137 Query: 121 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 + +++++H + M + I + P ++ + S + K E+ Sbjct: 138 A---------DEYEYVHFS--TGPNYLDMAKSIRSKIIFDPSQEIHKYSKDELKKFHEIS 186 Query: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 + + D + R + G + E G+ +L DGK Sbjct: 187 YMSIFNDHEY---------------RVFREMTGLSSPKVTTIVTNGERGS-SLFMDGKKY 230 Query: 241 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVA 285 A P DT+GAGD+F A + +L RS+++ + +G +A Sbjct: 231 DFPAIPSSG--DTVGAGDSFRAGLYLALYNRRSIEKGMIYGTIIA 273 >2QHP-A nrPDB Length = 296 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 27/48 (56%) Query: 246 PPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 P V DT+GAGD+F A+ S+ G+SV EA + +V+ C G Sbjct: 235 PKVPVADTVGAGDSFTAAFCASILNGKSVPEAHKLAVEVSAYVCTQSG 282 >3RY7-A nrPDB Length = 304 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/111 (20%), Positives = 51/111 (45%), Gaps = 2/111 (1%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCL-SQRWQRGGNASNSCTVLSLLGAPCAFMGS 62 +++ +G +D V++Y + + +Q+ GG +N + + A F+ Sbjct: 3 NKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITK 62 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH 113 + VADF++ DF+ +D S + ++ T + + N+ G TI ++ Sbjct: 63 IGTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITV-NAEGQNTIYVY 112 >5C40-A nrPDB Length = 330 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 57/280 (20%), Positives = 107/280 (38%), Gaps = 41/280 (14%) Query: 10 GLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVA 69 G + D++SL + PK I GG +N C + LGA + + + Sbjct: 22 GSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFG 81 Query: 70 DFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFE--- 126 + + + ++ + ++ +Q+K + II N+ G IV+ + ++ D Sbjct: 82 NDYIENLKQNDIS-TEFTYQTKDAATGTASIIVNNEGQNIIVIVAGANLLLNTEDLRAAA 140 Query: 127 ------KVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 KV + Q + I + E + M +R P ++ P Sbjct: 141 NVISRAKVMVCQ---LEITPATSLEALTMARRSGVKTLFNPAP-----AIADLDP----- 187 Query: 181 QLFGYGDVVFVSK---DVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDG 237 Q + DV ++ ++ L SA +A +++G +V LG +G Sbjct: 188 QFYTLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVII-------TLGAEG 240 Query: 238 KLLHSDAFPPP--------RVVDTLGAGDTFNASVIFSLS 269 ++ S P P + VDT GAGD+F ++ F L+ Sbjct: 241 CVVLSQTEPEPKHIPTEKVKAVDTTGAGDSFVGALAFYLA 280 >2AA0-A nrPDB Length = 383 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 26/41 (63%), Gaps = 5/41 (12%) Query: 249 RVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKC 289 ++VDT GAGD F +++LSQG++V++ C + G C Sbjct: 329 KIVDTNGAGDAFVGGFLYALSQGKTVKQ-----CIMCGNAC 364 >5EYN-A nrPDB Length = 323 Score = 35.8 bits (81), Expect = 0.023, Method: Compositional matrix adjust. Identities = 53/244 (21%), Positives = 102/244 (41%), Gaps = 24/244 (9%) Query: 40 GGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCC 99 GG +N ++ L AF G + F+ VD + + T S+ Sbjct: 44 GGAPANVAVAIARLSGRSAFFGRVGNDPFGRFMQQTLTDEQVDCQHLHFDPVHRT-STVV 102 Query: 100 IINNSNGNRTIVLHDTSLPDVSATDFEKV-DLTQFK---WIHIEGRNASEQ--------- 146 + + +G R+ T + SA F ++ D+ F+ W+H+ + Q Sbjct: 103 VDLDEHGERSF----TFMVKPSADQFLQLSDIPSFQKGEWLHVCSIALANQPSRSSTFAA 158 Query: 147 VKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHL-GFQSAE 205 + ++ + + + P ++ V E ++ + + + G DVV S++ + L G QS E Sbjct: 159 IAQMKEVGGYVSFDPNLRE-EVWSEPQELQATVMRAVGLADVVKFSEEELQFLTGTQSIE 217 Query: 206 EALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVI 265 E L+ + + ++V +GA P+ + + S P +DT GAGD F ++ Sbjct: 218 EGLQAIADF--QIPLVVVTLGAKGALVATPNSQQIVSGKAVKP--IDTTGAGDAFVGGLL 273 Query: 266 FSLS 269 + LS Sbjct: 274 YRLS 277 >6C9R-A nrPDB Length = 337 Score = 35.4 bits (80), Expect = 0.026, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 27/64 (42%) Query: 222 VCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 V +G D + PDG +H P D G GD F A + S G ++ + + G Sbjct: 234 VTTLGPKGVDLVEPDGTTIHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLG 293 Query: 282 CQVA 285 VA Sbjct: 294 SLVA 297 >2NWH-A nrPDB Length = 317 Score = 35.0 bits (79), Expect = 0.035, Method: Compositional matrix adjust. Identities = 33/107 (30%), Positives = 55/107 (51%), Gaps = 24/107 (22%) Query: 187 DVVFVSKDVAKHLGFQSAEEA------LR--GLYGRV-RKGAVLVCAWAEEGADALGPDG 237 D++F+++ A+ L ++AE LR GL G V +GA V A+ G + Sbjct: 184 DILFMNEAEARALTGETAENVRDWPNILRKAGLSGGVVTRGASEVVAFN-------GTEK 236 Query: 238 KLLHSDAFPPP---RVVDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 +LH PP V D GAGD + + ++++G++++EALR G Sbjct: 237 AILH-----PPLIREVKDVTGAGDAMASGYLAAIAEGKTIREALRQG 278 >3LOO-A nrPDB Length = 365 Score = 34.7 bits (78), Expect = 0.048, Method: Compositional matrix adjust. Identities = 64/293 (21%), Positives = 113/293 (38%), Gaps = 43/293 (14%) Query: 19 LVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLS-LLGAP--CAFMGSMAPGHVADFLVAD 75 L++KY E + GG+ NS V +L P F G + A L Sbjct: 69 LIEKYQAE----------YIAGGSVQNSLRVAQWILQRPRTAIFFGCVGQDEYARILEER 118 Query: 76 FRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSA----TDFEKVDLT 131 GV+V +Q +P+ C + + R++ + + D + +D + L Sbjct: 119 ATSNGVNVQ---YQRSATSPTGTCAVLVTGTQRSLCANLAAANDFTPEHLRSDGNRAYLQ 175 Query: 132 QFKWIHIEGR--NASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVV 189 ++ ++ G S + + +A T + + + + L ++F Y DV+ Sbjct: 176 GAQFFYVSGFFFTVSFESALSVAKEAAATGRMFMMNLSAPFVPQFYKNNLEEIFPYVDVL 235 Query: 190 FVSKDVAKHLG--FQSAEEALRGLYGRV---------RKGAVLVCAWAEEGADAL----- 233 F ++ A L F E LR + R+ RK V++ +G+D + Sbjct: 236 FGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKRKRIVIIT----QGSDPVLLIEA 291 Query: 234 GPDG-KLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVA 285 G D + P ++VDT GAGD F + L Q R+V ++ G A Sbjct: 292 GTDNVREFPVQKLAPEQMVDTNGAGDAFVGGFLAQLLQSRTVDVCIKCGIWAA 344 >3N1C-A nrPDB Length = 309 Score = 34.7 bits (78), Expect = 0.054, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 8/75 (10%) Query: 215 VRKGA--VLVCAWAEEGADALGPDGKL-LHSD----AFPPP-RVVDTLGAGDTFNASVIF 266 VRK A ++ A+ +LGP G L + S+ PPP + T+GAGD+ ++ Sbjct: 205 VRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTL 264 Query: 267 SLSQGRSVQEALRFG 281 L++ S++E +RFG Sbjct: 265 KLAENASLEEMVRFG 279 >3GBU-A nrPDB Length = 313 Score = 33.9 bits (76), Expect = 0.091, Method: Compositional matrix adjust. Identities = 61/283 (21%), Positives = 122/283 (43%), Gaps = 49/283 (17%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 I +G +++D+IS+ + K+ +R + GG +N +S LG + + + Sbjct: 4 IASIGELLIDLISVEEGDLKD---VRLFEK--HPGGAPANVAVGVSRLGVKSSLISKVGN 58 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHD------TSLPD 119 ++L+ + + VD + K T + + + +L+D +L D Sbjct: 59 DPFGEYLIEELSKENVDTRGIVKDEKKHT--GIVFVQLKGASPSFLLYDDVAYFNMTLND 116 Query: 120 VSATDFEKVDLTQFKWIHIEGRNASEQ--VKMLQRIDAHNTRQPPEQKIRVSV------E 171 ++ E+ + F + I RN S + +K++++I ++ + +R+ + E Sbjct: 117 INWDIVEEAKIVNFGSV-ILARNPSRETVMKVIKKIKG-SSLIAFDVNLRLDLWRGQEEE 174 Query: 172 VEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGAD 231 + K EE +L D+V S++ +L Q E KG++L A Sbjct: 175 MIKVLEESIKL---ADIVKASEEEVLYLENQGVE----------VKGSMLT-------AI 214 Query: 232 ALGPDG-KLLHSDAF---PPPRV--VDTLGAGDTFNASVIFSL 268 LGP G +L+ ++ P V +DT GAGD F A+++ + Sbjct: 215 TLGPKGFRLIKNETVVDVPSYNVNPLDTTGAGDAFMAALLVGI 257 >3KD6-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 21/133 (15%) Query: 162 PEQKIRVSVEVEKPR---------------EELFQLFGYGDVVFVSKDVAKHLGFQSAEE 206 PE +++V +++ P+ EEL ++ DV V+ A+ L S + Sbjct: 130 PELQLKVLDQIDDPKLVVCDTMNFWIEGKPEELKKVLARVDVFIVNDSEARLL---SGDP 186 Query: 207 ALRGLYGRVRKGA--VLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASV 264 L +R+ L+ E GA L D + + AFP + D GAGDTF Sbjct: 187 NLVKTARIIREMGPKTLIIKKGEHGA-LLFTDNGIFAAPAFPLESIYDPTGAGDTFAGGF 245 Query: 265 IFSLSQGRSVQEA 277 I L++ + EA Sbjct: 246 IGHLARCGNTSEA 258 >3HJ6-A nrPDB Length = 327 Score = 32.3 bits (72), Expect = 0.26, Method: Compositional matrix adjust. Identities = 33/110 (30%), Positives = 50/110 (45%), Gaps = 5/110 (4%) Query: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGK-L 239 ++ D V S D A+HL + E Y + AV++ EEG + DG+ + Sbjct: 201 EIISRADFVKPSLDDARHLFGPDSPENYVKRYLELGVKAVILT-LGEEGV--IASDGEEI 257 Query: 240 LHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKC 289 + AF VD GAGD F + I L G +V+ +++ G VA K Sbjct: 258 IRIPAFSED-AVDVTGAGDAFWSGFICGLLDGYTVKRSIKLGNGVAAFKI 306 >6CW5-A nrPDB Length = 332 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 4/42 (9%) Query: 250 VVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGL 291 V DT GAGD F + L G+S+Q+AL+ C VA CG+ Sbjct: 273 VKDTTGAGDCFAGYFVAGLMSGKSLQDALKT-CLVA---CGI 310 >4GM6-A nrPDB Length = 351 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 28/61 (45%) Query: 233 LGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQ 292 L G+ S+ + +VD +G GD + A+V+ + E ++F AG K + Sbjct: 268 LWTQGECWESEEYAIYPIVDRVGGGDAYTAAVLHGILSEWRPDETVKFATAAAGLKHSIH 327 Query: 293 G 293 G Sbjct: 328 G 328 >4US5-D nrPDB Length = 338 Score = 32.0 bits (71), Expect = 0.35, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 26/69 (37%), Gaps = 17/69 (24%) Query: 53 LGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSS--------CCIINNS 104 LG P A+ A F+ DF R +D + A+ DTPS CC ++ Sbjct: 184 LGLPYAY---------AHFITPDFTREAMDTYRAAFVPGPDTPSPRPILSVVVCCAETDA 234 Query: 105 NGNRTIVLH 113 R H Sbjct: 235 EAQRVYATH 243 >1RK2-A nrPDB Length = 309 Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust. Identities = 59/282 (20%), Positives = 115/282 (40%), Gaps = 26/282 (9%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 ++ +G + D I + +P + + GG +N GA AF+ Sbjct: 7 LVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFIACTGD 66 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH---DTSL-PDVS 121 + + + +D++ V+ KG++ I N G I +H + +L P + Sbjct: 67 DSIGESVRQQLATDNIDITPVSV-IKGESTGVALIFVNGEGENVIGIHAGANAALSPALV 125 Query: 122 ATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQ 181 E++ + +E + E V +I AH + K V++ RE + Sbjct: 126 EAQRERIANASALLMQLE--SPLESVMAAAKI-AH------QNKTIVALNPAPARELPDE 176 Query: 182 LFGYGDVVFVSKDVAKHLG---FQSAEEALRGLYGRVRKG--AVLVCAWAEEGADALGPD 236 L D++ ++ A+ L ++ E+A + KG VL+ + ++ + Sbjct: 177 LLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNGE 236 Query: 237 GKLLHSDAFPPPRV--VDTLGAGDTFNASVIFSLSQGRSVQE 276 G+ + P RV VDT+ AGDTFN ++I +L + + + E Sbjct: 237 GQRV-----PGFRVQAVDTIAAGDTFNGALITALLEEKPLPE 273 >4X8F-A nrPDB Length = 309 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 20/32 (62%) Query: 249 RVVDTLGAGDTFNASVIFSLSQGRSVQEALRF 280 + DT AGDTFN +++ L Q ++ A++F Sbjct: 246 KATDTTAAGDTFNGALVTGLLQEMPLESAIKF 277 >2JG5-A nrPDB Length = 306 Score = 31.2 bits (69), Expect = 0.62, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 6/71 (8%) Query: 215 VRKGAVLVCAWAEEGADALGPDGKLLHSDAF------PPPRVVDTLGAGDTFNASVIFSL 268 ++ G +LV A+ +LG DG + P +VV+T+G+GD+ A ++ + Sbjct: 200 IKYGRLLVDKGAQSVIVSLGGDGAIYIDKEISIKAVNPQGKVVNTVGSGDSTVAGMVAGI 259 Query: 269 SQGRSVQEALR 279 + G S+++A + Sbjct: 260 ASGLSIEKAFQ 270 >2ABQ-A nrPDB Length = 306 Score = 30.8 bits (68), Expect = 0.67, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 221 LVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRF 280 ++ ++A +GA +G + H + P V +++GAGD+ A + +L +G+S+++A+ F Sbjct: 214 ILVSFAGDGALFASAEG-MFHVNV-PSGEVRNSVGAGDSVVAGFLAALQEGKSLEDAVPF 271 Query: 281 GCQVAGKKCGLQGF 294 GF Sbjct: 272 AVAAGSATAFSDGF 285 >5KB6-A nrPDB Length = 363 Score = 30.8 bits (68), Expect = 0.74, Method: Compositional matrix adjust. Identities = 61/303 (20%), Positives = 114/303 (37%), Gaps = 69/303 (22%) Query: 27 DSEIRCLSQRWQRGGNASNSCTVLS-LLGAP---CAFMGSMAPGHVADFLVADFRRRGVD 82 D ++ + GG+ NS V L+ P F G + + L +R+ D Sbjct: 68 DELVKKFKVEYHAGGSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEIL----KRKAAD 123 Query: 83 VSQVA-WQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEK-VDLTQFKWIHIEG 140 A + + + P+ C + GNR++V +L + EK +DL + W+ +E Sbjct: 124 AHVDAHYYEQNEQPTGTCAACITGGNRSLV---ANLAAANCYKKEKHLDLER-NWVLVEK 179 Query: 141 RN-----------ASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKP------REELFQLF 183 + E V + R A N R ++ + P +E L + Sbjct: 180 ARVYYIAGFFLTVSPESVLKVARYAAENNR-------VFTLNLSAPFISQFFKEALMDVM 232 Query: 184 GYGDVVFVSKD----VAKHLGFQSAE--------EALRGLYGRVRKGAVLVCAWAEEGAD 231 Y D++F ++ A+ GF++ + +AL + + ++ + Sbjct: 233 PYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALPKVNSKRQRTVIFT--------- 283 Query: 232 ALGPDGKLLHSD----AFP-----PPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGC 282 G D ++ ++ AFP ++DT GAGD F + L + + E +R G Sbjct: 284 -QGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGH 342 Query: 283 QVA 285 A Sbjct: 343 YAA 345 >3KTN-A nrPDB Length = 346 Score = 30.4 bits (67), Expect = 0.94, Method: Compositional matrix adjust. Identities = 12/36 (33%), Positives = 22/36 (61%) Query: 247 PPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGC 282 P +D +GAGD + A +++ SQ S+++A+ F Sbjct: 269 PLLNLDRIGAGDAYAAGILYGYSQNWSLEKAVTFAT 304 >2DME-A nrPDB Length = 120 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 5/72 (6%) Query: 149 MLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEAL 208 +++R+ N + P E+ +V+ ++EK ELF F D + K+ + L F + Sbjct: 24 LMKRLTDSNLKVPEEKAAKVATKIEK---ELFSFFRDTDAKY--KNKYRSLMFNLKDPKN 78 Query: 209 RGLYGRVRKGAV 220 L+ +V KG V Sbjct: 79 NILFKKVLKGEV 90 >2I5B-A nrPDB Length = 271 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 5/54 (9%) Query: 227 EEGADAL--GPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEAL 278 E+ D L G ++L S+ P T GAG TF+A+V L++G V+EA+ Sbjct: 186 EKAVDVLYDGETAEVLESEMIDTPY---THGAGCTFSAAVTAELAKGAEVKEAI 236 >3UQ9-A nrPDB Length = 372 Score = 29.3 bits (64), Expect = 2.3, Method: Compositional matrix adjust. Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 38/144 (26%) Query: 177 EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 +E+ ++ Y ++VF G +S EA ++G + V A A AD D Sbjct: 227 KEVDEMISYSNIVF---------GNESEAEAYGEVHGLLED---TVHATARYIADLPFAD 274 Query: 237 GK--------------LLHSDA------------FPPPRVVDTLGAGDTFNASVIFSLSQ 270 GK LL++D+ F +++DT GAGD F A I + Sbjct: 275 GKKRKRLVIITRGKNPLLYTDSSDSEIHQFMVEQFKDDQIIDTNGAGDAFAAGFIADYIR 334 Query: 271 GRSVQEALRFGCQVAGKKCGLQGF 294 G+ + +L + A GF Sbjct: 335 GKPMITSLHAAVKAAAYIICRSGF 358 >3LJS-A nrPDB Length = 338 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 29/121 (23%), Positives = 53/121 (43%), Gaps = 12/121 (9%) Query: 3 EKQILCVGLVVLDVIS--LVDK-YPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAF 59 +K ILC G ++D+++ LV K P+ + ++C GG +N ++ LG F Sbjct: 4 KKTILCFGEALIDMLAQPLVKKGMPR--AFLQC------AGGAPANVAVAVARLGGAVQF 55 Query: 60 MGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPD 119 +G + DFL F GV + S T + + +++G R+ + D Sbjct: 56 VGMLGSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFVAL-DAHGERSFSFYRPPAAD 114 Query: 120 V 120 + Sbjct: 115 L 115 >3IQ0-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 49/241 (20%), Positives = 94/241 (39%), Gaps = 15/241 (6%) Query: 50 LSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRT 109 ++ LG PC + + D + GVD+ ++ T S+ +NS G+R Sbjct: 47 VTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNS-GDRD 105 Query: 110 IVLH--DTSLPDVSATDFEKVDLTQFKWIHIEGRN------ASEQVKMLQRIDAHNTRQP 161 + + + + +SA ++ L HI G + K + + A+ Sbjct: 106 FIFNIKNAACGKLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKANGGVIS 165 Query: 162 PEQKIRVS-VEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAV 220 + IR +++ + R+ L + D+ S+ L S E R + G + +G Sbjct: 166 FDPNIRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPE--RAIAGFLEEGVK 223 Query: 221 -LVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALR 279 ++ +GA + + H +++P V D GAGD F + I G AL+ Sbjct: 224 EVIVKRGNQGASYYSANEQF-HVESYPVEEV-DPTGAGDCFGGAWIACRQLGFDAHRALQ 281 Query: 280 F 280 + Sbjct: 282 Y 282 >3GU2-A nrPDB Length = 336 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 18/29 (62%) Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGD 93 P H++D ++ D RRRG+ QV + G+ Sbjct: 302 PLHISDDILPDLRRRGITEEQVGQMTVGN 330 >3LHX-A nrPDB Length = 319 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 13/37 (35%), Positives = 20/37 (54%) Query: 245 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 P +V+DT AGD+F+A + G S + A + G Sbjct: 253 LPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRG 289 >3B1N-A nrPDB Length = 326 Score = 27.3 bits (59), Expect = 7.4, Method: Compositional matrix adjust. Identities = 13/45 (28%), Positives = 19/45 (42%) Query: 249 RVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 RV+D G GD F +++ + G A R + K QG Sbjct: 244 RVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQG 288 >5FET-A nrPDB Length = 847 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 26/118 (22%), Positives = 54/118 (45%), Gaps = 10/118 (8%) Query: 81 VDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH-DTSLPDVSATDFEKVDLTQFKWIHIE 139 V+ +V KG + +I+N+ + TI+ D +L V + F + L Q + Sbjct: 101 VNDKKVKSMGKGSSFGEAALIHNTQRSATIMAETDGTLWGVQRSTF-RATLKQ-----LS 154 Query: 140 GRNASEQVKMLQRIDAHNTRQPPEQKIRVS---VEVEKPREELFQLFGYGDVVFVSKD 194 RN +E + + + ++ + + +++ KP E + + YGDV+F+ K+ Sbjct: 155 NRNFNENRSFIDSVSVFDMLTEAQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKE 212 >5EY6-A nrPDB Length = 217 Score = 26.9 bits (58), Expect = 9.4, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 189 VFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGP-DGKLLHSDAFPP 247 +F S+ + +++ + A+ +GLYG + W E + GP G L+ AF P Sbjct: 65 LFESRSICRYVCEKYADRGDKGLYGTNPLERASIDQWVEAEGQSFGPSSGALVFQLAFAP 124 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3NCA-A nrPDB 373 e-104 2HW1-A nrPDB 364 e-101 3UBO-A nrPDB 233 9e-62 4LC4-A nrPDB 231 2e-61 5ZWY-A nrPDB 222 1e-58 2C4E-A nrPDB 220 5e-58 2RBC-A nrPDB 216 1e-56 3H49-A nrPDB 212 2e-55 6ILS-A nrPDB 203 1e-52 1VM7-A nrPDB 194 4e-50 4DU5-A nrPDB 193 8e-50 2QCV-A nrPDB 188 2e-48 4WJM-A nrPDB 173 6e-44 1TYY-A nrPDB 162 1e-40 Sequences not found previously or not previously below threshold: 1RK2-A nrPDB 128 4e-30 5C40-A nrPDB 127 6e-30 5EYN-A nrPDB 126 9e-30 4X8F-A nrPDB 126 1e-29 3RY7-A nrPDB 126 2e-29 3HJ6-A nrPDB 122 2e-28 1V1S-A nrPDB 118 3e-27 3IQ0-A nrPDB 109 1e-24 2VAR-A nrPDB 109 1e-24 6CW5-A nrPDB 108 3e-24 1WYE-A nrPDB 106 2e-23 2AA0-A nrPDB 105 2e-23 3LOO-A nrPDB 104 5e-23 3GBU-A nrPDB 103 1e-22 3LHX-A nrPDB 102 2e-22 3B1N-A nrPDB 99 3e-21 3LJS-A nrPDB 98 4e-21 3PL2-A nrPDB 97 9e-21 4N08-A nrPDB 93 1e-19 5KB6-A nrPDB 93 2e-19 3UQ9-A nrPDB 92 3e-19 3BF5-A nrPDB 89 2e-18 2I6B-A nrPDB 89 3e-18 6C9R-A nrPDB 88 5e-18 2ABQ-A nrPDB 86 2e-17 2NWH-A nrPDB 85 3e-17 3GO6-A nrPDB 85 5e-17 2QHP-A nrPDB 81 8e-16 3I3Y-A nrPDB 80 1e-15 4E69-A nrPDB 78 4e-15 3KZH-A nrPDB 75 3e-14 2AFB-A nrPDB 75 3e-14 2AJR-A nrPDB 74 6e-14 4GM6-A nrPDB 74 1e-13 3KD6-A nrPDB 71 8e-13 4E84-A nrPDB 70 1e-12 3N1C-A nrPDB 61 7e-10 2JG5-A nrPDB 60 1e-09 3KTN-A nrPDB 59 3e-09 2AWD-A nrPDB 57 1e-08 3JUL-A nrPDB 52 3e-07 5YSQ-A nrPDB 48 6e-06 2I5B-A nrPDB 38 0.005 6C8Z-A nrPDB 36 0.018 4C5N-A nrPDB 34 0.090 3MBJ-A nrPDB 33 0.13 1TZ9-A nrPDB 33 0.15 5ZWB-B nrPDB 32 0.28 4US5-D nrPDB 32 0.34 2DDM-A nrPDB 30 1.1 5HX2-D nrPDB 30 1.1 4XF7-A nrPDB 30 1.2 1B9Y-C nrPDB 30 1.3 4BJP-A nrPDB 30 1.5 2D4W-A nrPDB 29 2.9 5GQ0-B nrPDB 29 3.2 1TD2-A nrPDB 28 3.7 6GNG-A nrPDB 28 4.5 >3NCA-A nrPDB Length = 313 Score = 373 bits (957), Expect = e-104, Method: Composition-based stats. Identities = 294/294 (100%), Positives = 294/294 (100%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA Sbjct: 20 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 79 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD 124 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD Sbjct: 80 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD 139 Query: 125 FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG 184 FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG Sbjct: 140 FEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG 199 Query: 185 YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA 244 YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA Sbjct: 200 YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDA 259 Query: 245 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 298 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV Sbjct: 260 FPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 313 >2HW1-A nrPDB Length = 298 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 270/298 (90%), Positives = 281/298 (94%) Query: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM 60 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM Sbjct: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM 60 Query: 61 GSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDV 120 GSMAPGHVADF++ D RR VD+ +Q+ G P + IIN ++G+RTI+ +D SLPDV Sbjct: 61 GSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDV 120 Query: 121 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF Sbjct: 121 SATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 Query: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL Sbjct: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 Query: 241 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 298 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV Sbjct: 241 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV 298 >3UBO-A nrPDB Length = 354 Score = 233 bits (593), Expect = 9e-62, Method: Composition-based stats. Identities = 74/317 (23%), Positives = 126/317 (39%), Gaps = 28/317 (8%) Query: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEI------------------RCLSQRWQRGGN 42 M + +L +G ++D+I+ D E++ I R GG+ Sbjct: 3 MAKYDVLTIGNAIVDIIARCDDSFLEENGIIKGAMNLINADRAELLYSRMGPAVEASGGS 62 Query: 43 ASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSC-CII 101 A N+ ++ LG A+ G +A + + D R +GV G P++ I Sbjct: 63 AGNTAAGVASLGGRAAYFGKVADDQLGEIFTHDIRAQGV--HFQTKPLDGHPPTARSMIF 120 Query: 102 NNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGR-----NASEQVKMLQRIDAH 156 +G R++ + + ++ D E + Q K + EG A + ++ RI AH Sbjct: 121 VTEDGERSMNTYLGACVELGPEDVEDDVVAQSKVTYFEGYLWDPPRAKDAIREAARI-AH 179 Query: 157 NTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVR 216 + + S V + R E +L G V V + + L E+ R L R Sbjct: 180 AHGRETAMTLSDSFCVHRYRSEFLELMRSGTVDIVFANRQEALALYETEDFDRALELLAR 239 Query: 217 KGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQE 276 + +EEG+ + + + A +VVDT GAGD + A +F + GRS++E Sbjct: 240 DCKLAAVTLSEEGSVVV-RGAERVRVGASVLEQVVDTTGAGDLYAAGFLFGYTSGRSLEE 298 Query: 277 ALRFGCQVAGKKCGLQG 293 + G AG G G Sbjct: 299 CSKLGNLAAGIVIGQIG 315 >4LC4-A nrPDB Length = 352 Score = 231 bits (589), Expect = 2e-61, Method: Composition-based stats. Identities = 75/318 (23%), Positives = 122/318 (38%), Gaps = 30/318 (9%) Query: 1 MEEKQILCVGLVVLDVIS------------------LVDKYPKEDSEIRCLSQRWQRGGN 42 M +L VG ++D+IS L+D E R GG+ Sbjct: 23 MTRFDVLTVGNAIVDIISRCNDQFLIDNQITKAAMNLIDAERAELLYSRMGPALEASGGS 82 Query: 43 ASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSS--CCI 100 A N+ ++ LG A+ G++A + D D R +GV + KG P + I Sbjct: 83 AGNTAAGVANLGGKAAYFGNVAADQLGDIFTHDIRAQGV---HYQTKPKGAFPPTARSMI 139 Query: 101 INNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGR-----NASEQVKMLQRIDA 155 +G R++ + + ++ D E + K + EG A E + RI A Sbjct: 140 FVTEDGERSMNTYLGACVELGPEDVEADVVADAKVTYFEGYLWDPPRAKEAILDCARI-A 198 Query: 156 HNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRV 215 H + + S V++ R E L G V V + + L ++ L Sbjct: 199 HQHGREMSMTLSDSFCVDRYRGEFLDLMRSGKVDIVFANRQEALSLYQTDDFEEALNRIA 258 Query: 216 RKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQ 275 + +E GA L + + +A VVDT GAGD F + ++ +QGRS++ Sbjct: 259 ADCKIAAVTMSENGAVILKGRERY-YVNAIRIREVVDTTGAGDLFASGFLYGYTQGRSLE 317 Query: 276 EALRFGCQVAGKKCGLQG 293 + + GC AG G Sbjct: 318 DCGKLGCLAAGIVIQQIG 335 >5ZWY-A nrPDB Length = 349 Score = 222 bits (566), Expect = 1e-58, Method: Composition-based stats. Identities = 67/305 (21%), Positives = 114/305 (37%), Gaps = 24/305 (7%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 IL VG LD + VD P+ + +S GG +N LGA A + + Sbjct: 37 DILVVGSCFLDYVGYVDHMPQVGETMHSVSFHKGFGGKGANQAVAAGRLGAKVAMVSMVG 96 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTS-------L 117 + + R GVD + + K T + +++ + N IV+ + L Sbjct: 97 TDGDGSDYIKELERNGVDTAYMFRTGKSSTGLAMILVDTKSSNNEIVICPNATNHFTPEL 156 Query: 118 PDVSATDFEKVDLTQFKWI----HIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173 ++E++ T K++ I + +K + VE Sbjct: 157 LRAQTNNYERILHTGLKYLICQNEIPLPTTLDTIKEAHSRGVYTVFNSAPAPKPAEVEQI 216 Query: 174 KPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWA-----EE 228 KP LF +V K +SA A++ L + V+ A E Sbjct: 217 KPFLPYVSLFCPNEVEATLITGVKVTDTESAFSAIKALQQLGVRDVVITLGAAGFVLSEN 276 Query: 229 GADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKK 288 GA+ + GK + + VDT GAGD F S+++ +S+GR++ EA + + A Sbjct: 277 GAEPVHVTGKHV--------KAVDTTGAGDCFVGSMVYFMSRGRNLLEACKRANECAAIS 328 Query: 289 CGLQG 293 +G Sbjct: 329 VTRKG 333 >2C4E-A nrPDB Length = 302 Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats. Identities = 54/294 (18%), Positives = 120/294 (40%), Gaps = 21/294 (7%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 63 ++I CVG LD I V+K+P+ ++ I+ S R GG A+N+ + LG + + Sbjct: 6 EKITCVGHTALDYIFNVEKFPEPNTSIQIPSARKYYGGAAANTAVGIKKLGVNSELLSCV 65 Query: 64 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSAT 123 + +++S++ + + +TP + + N T L + Sbjct: 66 GYDFKNSGYERYLKNLDINISKLYYSEEEETPKAWIFTDKDNNQITFFLWGAA------K 119 Query: 124 DFEKVDLTQF--KWIHIEGRNASEQVKMLQRIDAHN-TRQPPEQKIRVSVEVEKPREELF 180 +++++ F + +HI + +K ++ +N P Q + + +E L Sbjct: 120 HYKELNPPNFNTEIVHIATGDPEFNLKCAKKAYGNNLVSFDPGQDLP-----QYSKEMLL 174 Query: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALR-GLYGRVRKGAVLVCAWAEEGADALGPDGKL 239 ++ + + +F++K F+ A L + + + L+ +G+ D K Sbjct: 175 EIIEHTNFLFMNKHE-----FERASNLLNFEIDDYLERVDALIVTKGSKGSVIYTKDKK- 228 Query: 240 LHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 + +V+D GAGD++ A + + +G +++ G A +G Sbjct: 229 IEIPCIKAGKVIDPTGAGDSYRAGFLSAYVKGYDLEKCGLIGAATASFVVEAKG 282 >2RBC-A nrPDB Length = 343 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 65/292 (22%), Positives = 113/292 (38%), Gaps = 12/292 (4%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 63 K +LCVG VLD + V PK + ++ G AS++ + +G + G++ Sbjct: 30 KHVLCVGAAVLDTLFRVADMPKGEGKVLPYEVLQIAEGMASSAAYAVHRMGGRASLWGAV 89 Query: 64 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIV-LHDTSLPDVSA 122 ++ D G+D S + + S II+N G R IV +D L + Sbjct: 90 GDDETGTRILRDLSESGIDTSGMTVAPGARSALSTIIIDNR-GERLIVPFYDHRLHEKKR 148 Query: 123 TDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQL 182 + D+ F + ++ R + +L A + + P E L L Sbjct: 149 ACTPE-DIALFDAVLVDVRWPELALDVLTVARALGKPAILDGDV-------APVETLEGL 200 Query: 183 FGYGDVVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLH 241 + S+ A L G ++ ++ L L+ R + + V G D +H Sbjct: 201 APAATHIVFSEPAATRLTGLETVKDMLPVLHARYPQTFIAV-TAGPAGCWWTEADDPTVH 259 Query: 242 SDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 VDTL AGD F+ + ++++G + A+R A KC + G Sbjct: 260 FQTTMQVEAVDTLAAGDIFHGTFALAMAEGMQSRAAVRLSSVAAALKCTVFG 311 >3H49-A nrPDB Length = 325 Score = 212 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 65/308 (21%), Positives = 126/308 (40%), Gaps = 28/308 (9%) Query: 1 MEEKQILCVGLVVLDV--------ISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSL 52 ++ ++C+G ++D+ I VD YP E GG+A N T++S Sbjct: 3 LDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLE-------RIAMTTGGDAINEATIISR 55 Query: 53 LGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVL 112 LG A M + F++ R+ +D+ + DT + ++ +G RT V Sbjct: 56 LGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV-TEDGERTFVT 114 Query: 113 H-DTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVE 171 + + SL ++ D + +Q K + + S + + Q +++ + + Sbjct: 115 NRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEI--FTQAKARQMIICAD 172 Query: 172 VEKPR-----EELFQLFGYGDVVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVLVCAW 225 + KPR +++ + Y D +F + AK L G ++ +E K V+ Sbjct: 173 MIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLACGVKTVVI--KT 230 Query: 226 AEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVA 285 ++G + + A +DT+GAGD F + I +L +G++++E RF A Sbjct: 231 GKDGCF-IKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNLRECARFANATA 289 Query: 286 GKKCGLQG 293 G Sbjct: 290 AISVLSVG 297 >6ILS-A nrPDB Length = 313 Score = 203 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 65/303 (21%), Positives = 121/303 (39%), Gaps = 28/303 (9%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 ++ VG D+ +++ PKE I + + GG +N + L P F+G + Sbjct: 5 LVVVGSANADIYVEIERLPKEGETISAKTGQTLAGGKGANQAACGAKLMYPTYFVGRLGE 64 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIIN-NSNGNRTIVL----HDTSLPD- 119 + G V +S + P+ ++ S+G +I++ + + P+ Sbjct: 65 DAHGKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEI 124 Query: 120 VSATDFEKVD-----LTQFKW---IHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVE 171 +S D E V L Q + I+I+ A ++ + +D P ++ S++ Sbjct: 125 MSDDDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLDSID 184 Query: 172 VEKPRE-ELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230 + P E EL +L G F + +A+ + K + +G+ Sbjct: 185 ILSPNETELSRLTGMPTETF-----------EQISQAVAKCHKLGVKQVL--VKLGSKGS 231 Query: 231 DALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCG 290 K + P +VVDT GAGDTF A+ ++ +G+S +E LRF A Sbjct: 232 ALFIQGEKPIQQSIIPAAQVVDTTGAGDTFTAAFAVAMVEGKSHEECLRFAAAAASLCVQ 291 Query: 291 LQG 293 ++G Sbjct: 292 VKG 294 >1VM7-A nrPDB Length = 311 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 57/296 (19%), Positives = 114/296 (38%), Gaps = 27/296 (9%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAP-CAFMGSMA 64 I VG +D++ VD + K + + GG +N ++ +G C F+ + Sbjct: 17 ISVVGSSNIDIVLKVDHFTKPGETQKAIEMNVFPGGKGANQAVTVAKIGEKGCRFVTCIG 76 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIIN-NSNGNRTIVLHDTSLPDVSAT 123 +D L+ ++ + G+ + P+ I + G I++ + ++ Sbjct: 77 NDDYSDLLIENYEKLGI-----TGYIRVSLPTGRAFIEVDKTGQNRIIIFPGANAELKKE 131 Query: 124 DFEKVDLTQFKWIHIEGRNASEQ-VKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQL 182 + L++ + ++ E ++ +R + P + EE+FQ Sbjct: 132 LIDWNTLSESDILLLQNEIPFETTLECAKRFNGIVIFDPAP--------AQGINEEIFQY 183 Query: 183 FGY-----GDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDG 237 Y ++ +SKD F + E+A K ++ ++G + + Sbjct: 184 LDYLTPNEKEIEALSKDFFG--EFLTVEKAAEKFLELGVKN--VIVKLGDKGVLLVNKNE 239 Query: 238 KLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 K H F + VDT AGD FN + +LS+G++ +EA+ FG A G Sbjct: 240 KK-HFPTFKV-KAVDTTAAGDVFNGAFAVALSEGKNPEEAVIFGTAAAAISVTRLG 293 >4DU5-A nrPDB Length = 336 Score = 193 bits (490), Expect = 8e-50, Method: Composition-based stats. Identities = 60/301 (19%), Positives = 107/301 (35%), Gaps = 18/301 (5%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 63 ++ G ++ LV P +R G +N L+ LG + + Sbjct: 27 LDVITFGEAMM---LLVADRPGPLEHAEAFHKR--TAGAETNVAIGLARLGLKVGWASRL 81 Query: 64 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCC--IINNSNGNRTIVLHDTSLPDVS 121 + +L+A G+D S V + T + + S+ ++ + Sbjct: 82 GTDSMGRYLLAAMAAEGIDCSHVVCDATQKTGFQFKGKVTDGSDPPVEYHRKGSAASHMG 141 Query: 122 ATDFEKVDLTQFKWIHIEG---------RNASEQVKMLQRIDAHNTRQPPEQKIRVSVEV 172 D ++ L + +H G A+ + L R + P + + Sbjct: 142 VADIDEAWLLSARHLHATGVFPAISATTLPAARKTMDLMRAAGRSVSFDPNLRPTLWATP 201 Query: 173 EKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADA 232 E R+ + L D V + + L ++ E + Y ++ ++V EGA Sbjct: 202 ELMRDAINDLATRADWVLPGMEEGRFLTGETTPEGVARFYRQLG-AKLVVVKLGAEGAYF 260 Query: 233 LGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQ 292 G G FP VVDT+GAGD F VI +L G V EA++ G + + + Sbjct: 261 DGEAGSG-RVAGFPVAEVVDTVGAGDGFAVGVISALLDGLGVPEAVKRGAWIGARAVQVL 319 Query: 293 G 293 G Sbjct: 320 G 320 >2QCV-A nrPDB Length = 332 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 53/302 (17%), Positives = 119/302 (39%), Gaps = 23/302 (7%) Query: 3 EKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGS 62 E ++ +G +D+ ++ P E++ ++ GG+ +N S LG F+G Sbjct: 11 EFDLIAIGRACIDLNAVEYNRPMEET----MTFSKYVGGSPANIVIGSSKLGLKAGFIGK 66 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGN---RTIVLHDTSLPD 119 +A F+ + R GVD S + +G + + + D + Sbjct: 67 IADDQHGRFIESYMRGVGVDTSNLVVDQEGHK-TGLAFTEIKSPEECSILMYRQDVADLY 125 Query: 120 VSATDFEKVDLTQFKWIHIEG--------RNASEQVKMLQRIDAHNTRQPPEQKIRVSVE 171 +S + + + + K + + G R A + L + + + + Sbjct: 126 LSPEEVNEAYIRRSKLLLVSGTALSKSPSREAVLKAIRLAKRNDVKVVFELDYRPYSWET 185 Query: 172 VEKPREELFQLFGYGDVVFVSKDVAKHLGFQSA----EEALRGLYGRVRKGAVLVCAWAE 227 E+ + D+V +++ L ++ +E +R L+ + ++V Sbjct: 186 PEETAVYYSLVAEQSDIVIGTREEFDVLENRTEKGDNDETIRYLFKHSPE--LIVIKHGV 243 Query: 228 EGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGK 287 EG+ A G+ A+ +V+ T GAGD++ ++ +++L G+ ++ AL++G A Sbjct: 244 EGSFAYTKAGEAYRGYAYKT-KVLKTFGAGDSYASAFLYALISGKGIETALKYGSASASI 302 Query: 288 KC 289 Sbjct: 303 VV 304 >4WJM-A nrPDB Length = 312 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 69/283 (24%), Positives = 112/283 (39%), Gaps = 22/283 (7%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 ILC G L+D P+E + Q GG+ N+ L LG P F ++ Sbjct: 7 MILCCGEA------LIDMLPRETTGGETAFQP-FAGGSVFNTAIALGRLGVPTGFFSGIS 59 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHD--TSLPDVSA 122 D L R VD S A ++ P++ + +G +D T+ +S Sbjct: 60 SDFFGDVLRDTLARSNVDYSFAAISNR---PTTLAFVRLVDGQARYAFYDENTAGRMLSR 116 Query: 123 TDFEKVDLT----QFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVS-VEVEKPR- 176 D VD T F I + + L +A N + IR + + V K Sbjct: 117 NDMPYVDETISAMLFGCISLISEPCGSVYETLLAREAPNRVMFLDPNIRANLITVRKTHL 176 Query: 177 EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 + ++ D+V +S + G + + + + + ++ V++ A GA A Sbjct: 177 TRMKRMIALADIVKLSDEDLDWFGEKGSHDEIAAEWLKLGPKLVVITKGA-HGAVAYTNH 235 Query: 237 GKLLHSDAFPPPRVVDTLGAGDTFNASVIFSL-SQGRSVQEAL 278 + VVDT+GAGDT NA ++ SL SQG ++AL Sbjct: 236 -ATVPVPGVKV-DVVDTVGAGDTVNAGILASLHSQGLLTKDAL 276 >1TYY-A nrPDB Length = 339 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 73/314 (23%), Positives = 120/314 (38%), Gaps = 63/314 (20%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 ++ +G +D++ K++S ++C GG ++N ++ LG C F+G + Sbjct: 26 KVWVIGDASVDLVPE-----KQNSYLKC------PGGASANVGVCVARLGGECGFIGCLG 74 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIIN-NSNGNR--TIVLHDTSLPDVS 121 FL F+ GVDV+ + + D S+ I+N ++G R T ++H + VS Sbjct: 75 DDDAGRFLRQVFQDNGVDVTFL--RLDADLTSAVLIVNLTADGERSFTYLVHPGADTYVS 132 Query: 122 ATDFEKVDLTQFKWIH---------------IEGRNASEQVKMLQRIDAH-------NTR 159 D Q++W + +EG + D + NT Sbjct: 133 PQDLP--PFRQYEWFYFSSIGLTDRPAREACLEGARRMREAGGYVLFDVNLRSKMWGNTD 190 Query: 160 QPPEQKIRVSVEVEKPR---EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVR 216 + PE R + + +EL QL G Q A LR L Sbjct: 191 EIPELIARSAALASICKVSADELCQLSGASHW-------------QDARYYLRDL----- 232 Query: 217 KGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQE 276 + + +GA + +G+ H A P VVDT GAGD F ++F+LS+ Sbjct: 233 GCDTTIISLGADGALLITAEGE-FHFPA-PRVDVVDTTGAGDAFVGGLLFTLSRANCWDH 290 Query: 277 ALRFGCQVAGKKCG 290 AL CG Sbjct: 291 ALLAEAISNANACG 304 >1RK2-A nrPDB Length = 309 Score = 128 bits (320), Expect = 4e-30, Method: Composition-based stats. Identities = 54/293 (18%), Positives = 105/293 (35%), Gaps = 14/293 (4%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 ++ +G + D I + +P + + GG +N GA AF+ Sbjct: 7 LVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFIACTGD 66 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDF 125 + + + +D++ V+ T + +N G I +H + +S Sbjct: 67 DSIGESVRQQLATDNIDITPVSVIKGESTGVALIFVNGE-GENVIGIHAGANAALSPALV 125 Query: 126 E--KVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLF 183 E + + + ++ + E V +I N RE +L Sbjct: 126 EAQRERIANASALLMQLESPLESVMAAAKIAHQNKTIVALNPAPA-------RELPDELL 178 Query: 184 GYGDVVFVSKDVAKHLG---FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 D++ ++ A+ L ++ E+A + KG V +G+ Sbjct: 179 ALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNGEGQ 238 Query: 241 HSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 F + VDT+ AGDTFN ++I +L + + + EA+RF A +G Sbjct: 239 RVPGFRV-QAVDTIAAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKG 290 >5C40-A nrPDB Length = 330 Score = 127 bits (319), Expect = 6e-30, Method: Composition-based stats. Identities = 55/298 (18%), Positives = 101/298 (33%), Gaps = 27/298 (9%) Query: 10 GLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVA 69 G + D++SL + PK I GG +N C + LGA + + + Sbjct: 22 GSCMTDLVSLTSRLPKTGETIHGHKFFIGFGGKGANQCVQAARLGAMTSMVCKVGKDSFG 81 Query: 70 DFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKV- 128 + + + ++ + T ++ I+NN G IV+ + ++ D Sbjct: 82 NDYIENLKQNDISTEFTYQTKDAATGTASIIVNNE-GQNIIVIVAGANLLLNTEDLRAAA 140 Query: 129 -DLTQFKW----IHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLF 183 +++ K + I + E + M +R P + Q + Sbjct: 141 NVISRAKVMVCQLEITPATSLEALTMARRSGVKTLFNPAPAIADLDP----------QFY 190 Query: 184 GYGDVVFVSKDVAKHLGFQSAEEALR----GLYGRVRKGAVLVCAWAEEGADALGPDGKL 239 DV ++ A+ L + A L R V++ EG L Sbjct: 191 TLSDVFCCNESEAEILTGLTVGSAADAGEAALVLLKRGCQVVIITLGAEGCVVLSQTEP- 249 Query: 240 LHSDAFPPPRV--VDTLGAGDTFNASVIF--SLSQGRSVQEALRFGCQVAGKKCGLQG 293 P +V VDT GAGD+F ++ F + S+++ L +A G Sbjct: 250 -EPKHIPTEKVKAVDTTGAGDSFVGALAFYLAYYPNLSLEDMLNRSNFIAAVSVQAAG 306 >5EYN-A nrPDB Length = 323 Score = 126 bits (317), Expect = 9e-30, Method: Composition-based stats. Identities = 52/293 (17%), Positives = 107/293 (36%), Gaps = 29/293 (9%) Query: 18 SLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFR 77 ++VD P GG +N ++ L AF G + F+ Sbjct: 27 AVVDLIPDGQQH-----YLKCPGGAPANVAVAIARLSGRSAFFGRVGNDPFGRFMQQTLT 81 Query: 78 RRGVDVSQVAWQSKGDTPSSCCIINNSNGNR--TIVLHDTSLPDVSATDFEKVDLTQFKW 135 VD + + T + ++ +G R T ++ ++ + +D + +W Sbjct: 82 DEQVDCQHLHFDPVHRTSTVVVDLD-EHGERSFTFMVKPSADQFLQLSDIP--SFQKGEW 138 Query: 136 IHI--------EGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGD 187 +H+ R+++ + P + V E ++ + + + G D Sbjct: 139 LHVCSIALANQPSRSSTFAAIAQMKEVGGYVSFDPNLREEVWSEPQELQATVMRAVGLAD 198 Query: 188 VVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFP 246 VV S++ + L G QS EE L+ + ++V +GA P+ + + S Sbjct: 199 VVKFSEEELQFLTGTQSIEEGLQAIADFQIP--LVVVTLGAKGALVATPNSQQIVSG--K 254 Query: 247 PPRVVDTLGAGDTFNASVIFSLSQGRSV------QEALRFGCQVAGKKCGLQG 293 + +DT GAGD F +++ LS + +A+++ +G Sbjct: 255 AVKPIDTTGAGDAFVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKG 307 >4X8F-A nrPDB Length = 309 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 46/297 (15%), Positives = 108/297 (36%), Gaps = 20/297 (6%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 +++ +G V D + V +P+ + + + GG +N + + A F+ + Sbjct: 6 KLVVLGSVNADHVLQVPSFPRPGETLHGRNYQVIPGGKGANQAVAAARMQADVGFIACVG 65 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATD 124 + F+ G++ + V Q T + I + +G +I + + ++A Sbjct: 66 DDSFGINIRESFKLDGINTAGVKLQPNCPTGIA-MIQVSDSGENSICISAEANAKLTAAA 124 Query: 125 FEKVD--LTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQL 182 E + +++ ++ + + + RE +L Sbjct: 125 IEPDLAAIRDARYLLMQLETPLDGILKAAQEAKTAKTNVILNPAPA-------RELPDEL 177 Query: 183 FGYGDVVFVSKDVAKHLGFQSAEE------ALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 D++ ++ A+ L + + A L+ + + +++ +G L + Sbjct: 178 LKCVDLITPNETEAEVLTGITVYDDSSAQQAADALHCKGIE--IVIITLGSKG-VWLSQN 234 Query: 237 GKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 G+ F + DT AGDTFN +++ L Q ++ A++F A G Sbjct: 235 GRGQRIPGF-VVKATDTTAAGDTFNGALVTGLLQEMPLESAIKFAHAAAAISVTRFG 290 >3RY7-A nrPDB Length = 304 Score = 126 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 49/300 (16%), Positives = 110/300 (36%), Gaps = 24/300 (8%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGG-NASNSCTVLSLLGAPCAFMGSM 63 +++ +G +D V++Y + + + GG +N + + A F+ + Sbjct: 4 KVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKI 63 Query: 64 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSAT 123 VADF++ DF+ +D S + ++ T + I N+ G TI ++ + ++ Sbjct: 64 GTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQA-FITVNAEGQNTIYVYGGANMTMTPE 122 Query: 124 DF--EKVDLTQFKWIHIEGRNASEQVKMLQRID-AHNTRQPPEQKIRVSVEVEKPREELF 180 D K + ++ + + I AH ++ Sbjct: 123 DVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALP--------N 174 Query: 181 QLFGYGDVVFVSKDVAKHLG------FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALG 234 +L D++ ++ A+ L QS ++ K ++ Sbjct: 175 ELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGT---YFA 231 Query: 235 PDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGR-SVQEALRFGCQVAGKKCGLQG 293 + H +A+ +DT AGDTF + + L++ + ++ +A+ FG + + G Sbjct: 232 TKNQSQHIEAYKV-NAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHG 290 >3HJ6-A nrPDB Length = 327 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 56/300 (18%), Positives = 109/300 (36%), Gaps = 19/300 (6%) Query: 3 EKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGS 62 + ++ +G +++D+IS + +S + GG+ +N LS LG A + Sbjct: 21 DLDVVSLGEILVDMISTEE----VNSLSQSREYTRHFGGSPANIAVNLSRLGKKVALISR 76 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSA 122 + ++L+ + + + + T ++ S + + + + Sbjct: 77 LGADAFGNYLLDVLKGEQIITDGIQQDKERRTTI--VYVSKSTRTPDWLPYREADMYLQE 134 Query: 123 TDFEKVDLTQFKWIHI--------EGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEK 174 D + + K H+ R+ + + R P + + E + Sbjct: 135 DDIIFELIKRSKVFHLSTFILSRKPARDTAIKAFNYAREQGKIVCFDPCYRKVLWPEGDD 194 Query: 175 PREELFQLFGYGDVVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVLVCAWAEEGADAL 233 + ++ D V S D A+HL G S E ++ K +L EEG Sbjct: 195 GAGVVEEIISRADFVKPSLDDARHLFGPDSPENYVKRYLELGVKAVILTL--GEEG-VIA 251 Query: 234 GPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 +++ AF VD GAGD F + I L G +V+ +++ G VA K G Sbjct: 252 SDGEEIIRIPAF-SEDAVDVTGAGDAFWSGFICGLLDGYTVKRSIKLGNGVAAFKIRGVG 310 >1V1S-A nrPDB Length = 309 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 63/285 (22%), Positives = 106/285 (37%), Gaps = 19/285 (6%) Query: 19 LVDKYPKEDSEIRCLSQRW-QRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFR 77 LV P+E +R GG N L+ LG F+G + + + R Sbjct: 11 LVALVPQEPGHLRGKRLLEVYVGGAEVNVAVALARLGVKVGFVGRVGEDELGAMVEERLR 70 Query: 78 RRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIH 137 GVD++ + G ++ ++ F+ L +++H Sbjct: 71 AEGVDLTHFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALAPGAFDPDYLEGVRFLH 130 Query: 138 IEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEV---------EKPREELFQLFGYGDV 188 + G + + + + +RVS++V E+ R L + D+ Sbjct: 131 LSGITPALS-PEARAFSLWAMEEAKRRGVRVSLDVNYRQTLWSPEEARGFLERALPGVDL 189 Query: 189 VFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPP 248 +F+S++ A+ L F EEALR L +V +GA A DG+ + AF Sbjct: 190 LFLSEEEAELL-FGRVEEALRALSA-----PEVVLKRGAKGAWAF-VDGRRVEGSAF-AV 241 Query: 249 RVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 VD +GAGD F A + G V+E LR + +G Sbjct: 242 EAVDPVGAGDAFAAGYLAGAVWGLPVEERLRLANLLGASVAASRG 286 >3IQ0-A nrPDB Length = 330 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 50/303 (16%), Positives = 111/303 (36%), Gaps = 18/303 (5%) Query: 1 MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFM 60 M ++ +G +++++++ P + I G + ++ LG PC + Sbjct: 1 MSLSKVFTIGEILVEIMASKIGQPFDQPGIWNGP---YPSGAPAIFIDQVTRLGVPCGII 57 Query: 61 GSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH--DTSLP 118 + D + GVD+ ++ T S+ + +++G+R + + + + Sbjct: 58 SCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSA-FVTYHNSGDRDFIFNIKNAACG 116 Query: 119 DVSATDFEKVDLTQFKWIHIEGR--------NASEQVKMLQRIDAHNTRQPPEQKIRVSV 170 +SA ++ L HI G +A ++ + + + P + + + Sbjct: 117 KLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKANGGVISFDPNIRKEM-L 175 Query: 171 EVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGA 230 ++ + R+ L + D+ S+ L S E R + G + +G V Sbjct: 176 DIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPE--RAIAGFLEEGVKEVIVKRGNQG 233 Query: 231 DALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCG 290 + + H +++P VD GAGD F + I G AL++ Sbjct: 234 ASYYSANEQFHVESYPVEE-VDPTGAGDCFGGAWIACRQLGFDAHRALQYANACGALAVT 292 Query: 291 LQG 293 +G Sbjct: 293 RRG 295 >2VAR-A nrPDB Length = 313 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 51/301 (16%), Positives = 101/301 (33%), Gaps = 22/301 (7%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 ++ +G ++ S P + G+ N C + C+ + + Sbjct: 3 DVIALGEPLIQFNSF---NPGPLRFVN--YFEKHVAGSELNFCIAVVRNHLSCSLIARVG 57 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTP---SSCCIINNSNGNRTIVLHDTSLPDVS 121 ++ R +G+D S + ++ T ++ +S Sbjct: 58 NDEFGKNIIEYSRAQGIDTSHIKVDNESFTGIYFIQRGYPIPMKSELVYYRKGSAGSRLS 117 Query: 122 ATDFEKVDLTQFKWIHIEGR------NASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKP 175 D + + + +H G NA E V + A + + ++ +EK Sbjct: 118 PEDINENYVRNSRLVHSTGITLAISDNAKEAVIKAFEL-AKSRSLDTNIRPKLWSSLEKA 176 Query: 176 REELFQLFGYGDVVFVSKDVAK---HLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADA 232 +E + + D+ + D L +EA R K VL+ +GA A Sbjct: 177 KETILSILKKYDIEVLITDPDDTKILLDVTDPDEAYRKYKELGVK--VLLYKLGSKGAIA 234 Query: 233 LGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQ 292 + K DA+ P V D GAGD + + QG+ ++ +L G + ++ Sbjct: 235 YKDNVKAFK-DAYKVP-VEDPTGAGDAMAGTFVSLYLQGKDIEYSLAHGIAASTLVITVR 292 Query: 293 G 293 G Sbjct: 293 G 293 >6CW5-A nrPDB Length = 332 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 52/301 (17%), Positives = 97/301 (32%), Gaps = 23/301 (7%) Query: 7 LCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPG 66 L G V +D + + I + GG +N ++ G G++ Sbjct: 16 LVRGSVNIDEFFHLPHIVRPGETISSTGLTKRAGGKGANQAFAVARAGGQVELDGAIGDD 75 Query: 67 HVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFE 126 ++ GV ++ T + I + ++G +IVLH + + + Sbjct: 76 --GIWVKEMLESAGVGTDKLKIVKDEVTGRAV-IQSAADGENSIVLHAGANYYL-PSPTP 131 Query: 127 KVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTR-----QPPEQKIRVSVEVEKPREELFQ 181 L + + ++ ++ P + + E P + L Sbjct: 132 TTSLATYTHLLVQNEVPLSSTLAYLTAAGQSSPPLTSVFNPSPMLTPAQLREFPWKHLSW 191 Query: 182 LF----GYGDVVFVSKDVAKHLGFQSAEEALRG--------LYGRVRKGAVLVCAWAEEG 229 L GD++ A + E + K ++C +G Sbjct: 192 LIVNEGELGDLLLAFGSSANPGEAKEDELQAKASAGILELHENDYFSKNVGIICTLGAKG 251 Query: 230 ADALGPDGKLLHSDAFPPPRVV-DTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKK 288 P ++ + A V DT GAGD F + L G+S+Q+AL+ C VA Sbjct: 252 ILCYEPGKEVGYLPAAKLQNPVKDTTGAGDCFAGYFVAGLMSGKSLQDALK-TCLVACGI 310 Query: 289 C 289 C Sbjct: 311 C 311 >1WYE-A nrPDB Length = 311 Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 52/301 (17%), Positives = 104/301 (34%), Gaps = 24/301 (7%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMA 64 +++ +G ++++ +L P + G+ +N C G C + + Sbjct: 3 KLITLGEILIEFNAL---SPGPLRHVS--YFEKHVAGSEANYCVAFIKQGNECGIIAKVG 57 Query: 65 PGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNS-----NGNRTIVLHDTSLPD 119 + R +GVDVS + P+ I ++ Sbjct: 58 DDEFGYNAIEWLRGQGVDVSHMKIDPSA--PTGIFFIQRHYPVPLKSESIYYRKGSAGSK 115 Query: 120 VSATDFEKVDLTQFKWIHIEGR------NASEQVKMLQRIDAHNTRQPPEQKIRVSVEVE 173 +S D ++ + +H G A E V I A N ++++ E Sbjct: 116 LSPEDVDEEYVKSADLVHSSGITLAISSTAKEAVYKAFEI-ASNRSFDTNIRLKLWSAEE 174 Query: 174 KPREELFQLFG-YGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADA 232 RE L L + + D +K + +S + + + ++V +GA Sbjct: 175 AKREILKLLSKFHLKFLITDTDDSKIILGESDPDKAAKAFSDYAE--IIVMKLGPKGAIV 232 Query: 233 LGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQ 292 DGK +S + P V D GAGD + + +G +++AL + + ++ Sbjct: 233 YY-DGKKYYSSGYQVP-VEDVTGAGDALGGTFLSLYYKGFEMEKALDYAIVASTLNVMIR 290 Query: 293 G 293 G Sbjct: 291 G 291 >2AA0-A nrPDB Length = 383 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 51/346 (14%), Positives = 106/346 (30%), Gaps = 63/346 (18%) Query: 6 ILCVGLVVLDVISLVDKYPKED-------------------SEIRCLSQRWQRGGNASNS 46 + +G +LD+++ V ++ S + + GG+A NS Sbjct: 35 VFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQFNPTSLPGGSALNS 94 Query: 47 CTVLSLL---GAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINN 103 V+ L +MG++ L + G+ + T +IN Sbjct: 95 VRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFM-VAPGQSTGVCAVLINE 153 Query: 104 SNGNRTIVLHDTSLPDVSATDFEKVDLT---QFKWIHIEGRNASEQVKMLQRIDAHNTRQ 160 RT+ H + + + T + + K + + Sbjct: 154 K--ERTLCTHLGAC---GSFRLPEDWTTFASGALIFYATAYTLTATPKNALEVAGYAHGI 208 Query: 161 PPE---QKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG--------FQSAEEALR 209 P + VE ++ + L + +++F +++ HL ++A Sbjct: 209 PNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAEKTALSTAN 268 Query: 210 ------------GLYGRVRKGAVLVCAWAEEGADALGPDGKLLHS---------DAFPPP 248 L + + G + + + Sbjct: 269 KEHAVEVCTGALRLLTAGQNTSATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAE 328 Query: 249 RVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGF 294 ++VDT GAGD F +++LSQG++V++ + G A GF Sbjct: 329 KIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQDVIQHVGF 374 >3LOO-A nrPDB Length = 365 Score = 104 bits (259), Expect = 5e-23, Method: Composition-based stats. Identities = 50/307 (16%), Positives = 102/307 (33%), Gaps = 31/307 (10%) Query: 16 VISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAP---CAFMGSMAPGHVADFL 72 +++ P I + GG+ NS V + F G + A L Sbjct: 56 ILAEEKHMPMYQELIEKYQAEYIAGGSVQNSLRVAQWILQRPRTAIFFGCVGQDEYARIL 115 Query: 73 VADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDF----EKV 128 GV+V Q +P+ C + + R++ + + D + + Sbjct: 116 EERATSNGVNVQY---QRSATSPTGTCAVLVTGTQRSLCANLAAANDFTPEHLRSDGNRA 172 Query: 129 DLTQFKWIHIEGRNA----SEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFG 184 L ++ ++ G + + + A + + + L ++F Sbjct: 173 YLQGAQFFYVSGFFFTVSFESALSVAKEAAATGRMFM--MNLSAPFVPQFYKNNLEEIFP 230 Query: 185 YGDVVFVSKDVAKHL------GFQSAEEALRGLYGR----VRKGAVLVCAWAEEGADALG 234 Y DV+F ++ A L G + E + + ++ +++ + + Sbjct: 231 YVDVLFGNETEAIALAKEFNYGTEDLREIGKRIAALPKENGKRKRIVIITQGSDPVLLIE 290 Query: 235 PDGKLLH---SDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGL 291 + P ++VDT GAGD F + L Q R+V ++ G A + Sbjct: 291 AGTDNVREFPVQKLAPEQMVDTNGAGDAFVGGFLAQLLQSRTVDVCIKCGIWAAREIIQR 350 Query: 292 QG--FDG 296 G F+G Sbjct: 351 SGCTFEG 357 >3GBU-A nrPDB Length = 313 Score = 103 bits (255), Expect = 1e-22, Method: Composition-based stats. Identities = 51/299 (17%), Positives = 116/299 (38%), Gaps = 29/299 (9%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 I +G +++D+IS+ +E GG +N +S LG + + + Sbjct: 4 IASIGELLIDLISV-----EEGDLKDVRLFEKHPGGAPANVAVGVSRLGVKSSLISKVGN 58 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDT-SLPDVSATD 124 ++L+ + + VD + K T + + + +L+D + +++ D Sbjct: 59 DPFGEYLIEELSKENVDTRGIVKDEKKHT--GIVFVQLKGASPSFLLYDDVAYFNMTLND 116 Query: 125 FEKVDLTQFKWIHIEG----RNASEQ--VKMLQRIDAHN-TRQPPEQKIRVSVEV-EKPR 176 + + K ++ RN S + +K++++I + ++ + E+ Sbjct: 117 INWDIVEEAKIVNFGSVILARNPSRETVMKVIKKIKGSSLIAFDVNLRLDLWRGQEEEMI 176 Query: 177 EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 + L + D+V S++ +L Q E KG++L L + Sbjct: 177 KVLEESIKLADIVKASEEEVLYLENQGVE----------VKGSMLTAITLGPKGFRLIKN 226 Query: 237 GKLLHSDAFPPPRVVDTLGAGDTFNASVIFSL--SQGRSVQEALRFGCQVAGKKCGLQG 293 ++ ++ +DT GAGD F A+++ + +G + + +F VA +G Sbjct: 227 ETVVDVPSYNVNP-LDTTGAGDAFMAALLVGILKLKGLDLLKLGKFANLVAALSTQKRG 284 >3LHX-A nrPDB Length = 319 Score = 102 bits (253), Expect = 2e-22, Method: Composition-based stats. Identities = 55/314 (17%), Positives = 111/314 (35%), Gaps = 41/314 (13%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCA----F 59 K+I +G ++++ + + GG+ N+ ++ P A + Sbjct: 5 KKIAVIGECMIEL------------SEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHY 52 Query: 60 MGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSL-- 117 + ++ + ++ + VD S + + + P I +S G RT Sbjct: 53 VTALGTDSFSQQMLDAWHGENVDTS-LTQRMENRLPGLYYIETDSTGERTFYYWRNEAAA 111 Query: 118 -----PDVSATDFEKVDLTQFKWIHIEG-------RNASEQVKMLQR---IDAHNTRQPP 162 + SA E+ L F ++++ G + E++ L R Sbjct: 112 KFWLASEQSAAICEE--LANFDYLYLSGISLAILSPTSREKLLSLLRECRAKGGKVIFDN 169 Query: 163 EQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHL-GFQSAEEALRGLYGRVRKGAVL 221 + R+ E+ ++ Q+ D+ F++ D L G Q E+ + + K + Sbjct: 170 NYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKE--V 227 Query: 222 VCAWAEEGADALGPDGKLLHSDAFPPPR--VVDTLGAGDTFNASVIFSLSQGRSVQEALR 279 V + L+ A P+ V+DT AGD+F+A + G S + A + Sbjct: 228 VVKRGADSCLVSIAGEALVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAK 287 Query: 280 FGCQVAGKKCGLQG 293 G A +G Sbjct: 288 RGHLTASTVIQYRG 301 >3B1N-A nrPDB Length = 326 Score = 98.8 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 50/297 (16%), Positives = 86/297 (28%), Gaps = 22/297 (7%) Query: 7 LCVGLVVLDVISLVDKYPKE----------DSEIRCLSQRWQRGGNASNSCTVLSLLGAP 56 L G + D I + +E + + R + GG A N L+LLG Sbjct: 4 LICGSIAYDNIMTFEGRFREHILPDQVHLINLSFLVPTMRREFGGCAGNIAYALNLLGGD 63 Query: 57 CAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTS 116 MG++ +L G+ V + + + N T H + Sbjct: 64 ARMMGTLGAVDAQPYL-DRMDALGLSREYVRVLPDTYSAQAMITTDLDNNQIT-AFHPGA 121 Query: 117 LPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPR 176 + + + + +G Q P Q + + Sbjct: 122 MMQSHVNHAGEAKDIKLAIVGPDGFQGMVQHTEELAQAGVPFIFDPGQGLPLFDGA---- 177 Query: 177 EELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPD 236 L + + V+ AK + ++ + L+ E GA D Sbjct: 178 -TLRRSIELATYIAVNDYEAKLVCDKTGWSE----DEIASRVQALIITRGEHGATIRHRD 232 Query: 237 GKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 G A RV+D G GD F +++ + G A R + K QG Sbjct: 233 G-TEQIPAVRAERVIDPTGCGDAFRGGLLYGIEHGFDWATAGRLASLMGALKIAHQG 288 >3LJS-A nrPDB Length = 338 Score = 98.0 bits (242), Expect = 4e-21, Method: Composition-based stats. Identities = 57/315 (18%), Positives = 103/315 (32%), Gaps = 31/315 (9%) Query: 3 EKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGS 62 +K ILC G ++D+++ P + + GG +N ++ LG F+G Sbjct: 4 KKTILCFGEALIDMLAQ----PLVKKGM-PRAFLQCAGGAPANVAVAVARLGGAVQFVGM 58 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLH--DTSLPDV 120 + DFL F GV + S T + ++ ++G R+ + + Sbjct: 59 LGSDMFGDFLFDSFAEAGVVTDGIVRTSTAKTALAFVALD-AHGERSFSFYRPPAADLLF 117 Query: 121 SATDFEKVDLTQFKWIHI------EGRNASEQVKMLQRIDAHN--TRQPPEQKIRVSVEV 172 F+ + H + A + ++R A + + Sbjct: 118 RVEHFQDASFSDALIFHACSNSMTDADIAEVTFEGMRRAQAAGAIVSFDLNFRPMLWPNG 177 Query: 173 EKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADA 232 E P L++ DVV +S + +L A +A + + A L+ G Sbjct: 178 ENPASRLWKGLSLADVVKLSSEELDYLANTLAADANAVIQQLWQGRAQLLLVTDAAGPVH 237 Query: 233 LGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEA--------------L 278 F +V D+ AGD F ++++ +Q A L Sbjct: 238 WYTRTAGGEVPTFRV-QVQDSNAAGDAFVGGMLYTFAQQFDDAAALIDFCHDPESIVSTL 296 Query: 279 RFGCQVAGKKCGLQG 293 RF V QG Sbjct: 297 RFAAAVGALAVTRQG 311 >3PL2-A nrPDB Length = 319 Score = 96.9 bits (239), Expect = 9e-21, Method: Composition-based stats. Identities = 54/297 (18%), Positives = 107/297 (36%), Gaps = 24/297 (8%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRC--LSQRWQRGGNASNSCTVLSLLGAPCAFMGS 62 ++L +G + +D+ YP + S GG+A+N + G A + Sbjct: 10 EVLAIGRLGVDI------YPLQSGVGLADVQSFGKYLGGSAANVSVAAARHGHNSALLSR 63 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSA 122 + ++L+A+ R GVD VA TP + C I + + PD++ Sbjct: 64 VGNDPFGEYLLAELERLGVDNQYVATDQTFKTPVTFCEIFPPDDFPLYFYREPKAPDLNI 123 Query: 123 T--DFEKVDLTQFKWIHI--------EGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEV 172 D D+ + + R ++ R + +T + + Sbjct: 124 ESADVSLDDVREADILWFTLTGFSEEPSRGTHREILT-TRANRRHTIFDLDYRPMFWESP 182 Query: 173 EKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEE-ALRGLYGRVRKGAVLVCAWAEEGAD 231 E+ ++ + V +K+ + ++ E A R L R + + + +G Sbjct: 183 EEATKQAEWALQHSTVAVGNKEECEIAVGETEPERAGRALLERGVE--LAIVKQGPKGVM 240 Query: 232 ALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKK 288 A+ D + + F V++ LGAGD F ++ L +++ LRF Sbjct: 241 AMTKD-ETVEVPPF-FVDVINGLGAGDAFGGALCHGLLSEWPLEKVLRFANTAGALV 295 >4N08-A nrPDB Length = 348 Score = 93.4 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 45/287 (15%), Positives = 94/287 (32%), Gaps = 29/287 (10%) Query: 31 RCLSQRWQRGGNASNSCTVLSLL-----GAPCAFMGSMAPGHVADFLVADFRRRGVDVSQ 85 + + R+ GG+ N V + G ++G +A L G+ ++ Sbjct: 56 KMPNVRYVPGGSGLNVARVAQWMQQAYKGKFVTYVGCIADDRYGKVLKEAAEHEGIVMAV 115 Query: 86 VAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDF-EKVDLT---QFKWIHIEGR 141 G + CI RT+V + +S+ + + + + G Sbjct: 116 EHTTKAGSGACAVCITGK---ERTLVADLGAANHLSSEHMRSPAVVRAMDESRIFYFSGF 172 Query: 142 NASEQVKMLQRIDAHNTRQPPEQ----KIRVSVEVEKPREELFQLFGYGDVVFVSKDVAK 197 V + + A + + + ++ +L ++ Y D++ ++ AK Sbjct: 173 T--LTVDVNHVLQACRKAREVDGLFMINLSAPFIMQFFSAQLGEVLPYTDIIVANRHEAK 230 Query: 198 HLGF----------QSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDG-KLLHSDAFP 246 + A A+ + KG V+V E DG + + Sbjct: 231 EFANMMKWDTDCVEEIARRAVSEVPYTGTKGRVVVFTRDIESTVLATKDGVETVPVPQLD 290 Query: 247 PPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 +V+D GAGD F + + + G+ ++ G A + G Sbjct: 291 QDKVIDMNGAGDAFMGGFLSAYAVGKDLRRCCETGHYTAQEVIQRDG 337 >5KB6-A nrPDB Length = 363 Score = 92.6 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 58/337 (17%), Positives = 110/337 (32%), Gaps = 49/337 (14%) Query: 1 MEEKQILCVGLVVLDVISLVDKYP------KEDSEIRCLSQRW--------------QRG 40 + E + +G +LD+ ++VDK K + +I + G Sbjct: 22 LSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAG 81 Query: 41 GNASNSCTVLSLL---GAPCA-FMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPS 96 G+ NS V L A F G + + L VD + + P+ Sbjct: 82 GSTQNSMKVAQWLIQEPHKAATFFGCIGIDKFGEILKRKAADAHVDAHYY---EQNEQPT 138 Query: 97 SCCIINNSNGNRTIVLHDTSLPDVSAT---DFEKVDLT--QFKWIHIEGRN----ASEQV 147 C + GNR++V + + D E+ + + + +I G + Sbjct: 139 GTCAACITGGNRSLVANLAAANCYKKEKHLDLERNWVLVEKARVYYIAGFFLTVSPESVL 198 Query: 148 KMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEA 207 K+ + +N + +E L + Y D++F ++ A + E Sbjct: 199 KVARYAAENNRVFTLNLSAP--FISQFFKEALMDVMPYVDILFGNETEAATFAREQGFET 256 Query: 208 --LRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL----HSDAFPP-----PRVVDTLGA 256 ++ + + + + G D ++ AFP ++DT GA Sbjct: 257 KDIKEIAKKAQALPKVNSKRQRTVIFTQGRDDTIVAAENDVTAFPVLDQNQEEIIDTNGA 316 Query: 257 GDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 GD F + L + + E +R G A G Sbjct: 317 GDAFVGGFLSQLVSDKPLTECIRAGHYAASVIIRRTG 353 >3UQ9-A nrPDB Length = 372 Score = 91.9 bits (226), Expect = 3e-19, Method: Composition-based stats. Identities = 41/302 (13%), Positives = 103/302 (34%), Gaps = 25/302 (8%) Query: 16 VISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAP---CAFMGSMAPGHVADFL 72 V++ D + + GG N+ ++ + C+++G + ++ Sbjct: 59 VLAEEKHMTIYDEIQKKKKLNYIAGGATLNTVKMIQWIIQKPFVCSYVGCIGADIQGKYI 118 Query: 73 VADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFE----KV 128 D + + T +++ R++V + + D+S E Sbjct: 119 KNDCSALDLVTEFQIAEEPLMTGKVAVLVSEK--LRSMVTYLGAACDLSLAHIEQPHVWS 176 Query: 129 DLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPP--EQKIRVSVEVEKPREELFQLFGYG 186 + + + +I G + + + +I H+ + + +E+ ++ Y Sbjct: 177 LVEKAQVYYIAGFVINTCYEGMLKIAKHSLENEKLFCFNLSAPFLSQFNTKEVDEMISYS 236 Query: 187 DVVFVSKDVAKHLGF------QSAEEALRGLYGR-----VRKGAVLVCAWAEEGADALGP 235 ++VF ++ A+ G + R + ++ +++ + Sbjct: 237 NIVFGNESEAEAYGEVHGLLEDTVHATARYIADLPFADGKKRKRLVIITRGKNPLLYTDS 296 Query: 236 DGKLLH---SDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQ 292 +H + F +++DT GAGD F A I +G+ + +L + A Sbjct: 297 SDSEIHQFMVEQFKDDQIIDTNGAGDAFAAGFIADYIRGKPMITSLHAAVKAAAYIICRS 356 Query: 293 GF 294 GF Sbjct: 357 GF 358 >3BF5-A nrPDB Length = 306 Score = 89.2 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 55/288 (19%), Positives = 104/288 (36%), Gaps = 33/288 (11%) Query: 10 GLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVA 69 G + +DV+ VD P+E S + R + GG A N V P ++ Sbjct: 27 GHLNIDVLISVDSIPREGS-VNVKDLRPRFGGTAGNFAIVAQKFRIPFDLYSAVGMKTHR 85 Query: 70 DFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVD 129 ++L A G++ V P + + +H ++ + ++ Sbjct: 86 EYL-AMIESMGINTGHVEKFEDESGPICYIATDGKK-QVSF-MHQGAMAAWAPQLADE-- 140 Query: 130 LTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVV 189 ++++H + M + I + P Q+I + ++EL + + Sbjct: 141 ---YEYVHFSTGPNY--LDMAKSIRS-KIIFDPSQEIH-----KYSKDELKKFHEISYMS 189 Query: 190 FVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPR 249 + + R + G + E G+ +L DGK A P Sbjct: 190 IFNDHEYRVF---------REMTGLSSPKVTTIVTNGERGS-SLFMDGKKYDFPAIPSSG 239 Query: 250 VVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGI 297 DT+GAGD+F A + +L RS+++ + +G +A DGI Sbjct: 240 --DTVGAGDSFRAGLYLALYNRRSIEKGMIYGTIIAHHVID----DGI 281 >2I6B-A nrPDB Length = 345 Score = 88.8 bits (218), Expect = 3e-18, Method: Composition-based stats. Identities = 52/331 (15%), Positives = 107/331 (32%), Gaps = 53/331 (16%) Query: 9 VGLVVLDVISLVDKYP------KEDSEIRCLSQRW--------------QRGGNASNSCT 48 +G +LD+ ++VDK K + +I + GG+ NS Sbjct: 12 MGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNS-I 70 Query: 49 VLSLLGAP-----CAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINN 103 ++ F G + + L VD + + P+ C Sbjct: 71 KVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYY---EQNEQPTGTCAACI 127 Query: 104 SNGNRTIVLHDTSLPDVSAT---DFEKVDLT--QFKWIHIEGRN----ASEQVKMLQRID 154 + NR+++ + + D EK + + + +I G +K+ Sbjct: 128 TGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHAS 187 Query: 155 AHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGR 214 +N + +E L ++ Y D++F ++ A + E + + Sbjct: 188 ENNRIFTLNLSAP--FISQFYKESLMKVMPYVDILFGNETEAATFAREQGFET-KDIKEI 244 Query: 215 VRKGAVLVCAWAEEGADAL---GPDGKLLHSDAFPPP---------RVVDTLGAGDTFNA 262 +K L ++ + G D ++ +++ ++DT GAGD F Sbjct: 245 AKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVG 304 Query: 263 SVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 + L + + E +R G A G Sbjct: 305 GFLSQLVSDKPLTECIRAGHYAASIIIRRTG 335 >6C9R-A nrPDB Length = 337 Score = 87.6 bits (215), Expect = 5e-18, Method: Composition-based stats. Identities = 48/261 (18%), Positives = 81/261 (31%), Gaps = 16/261 (6%) Query: 37 WQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPS 96 RGG A N + +LG A +G+ AD+ + RGV+ V T Sbjct: 57 MHRGGVAGNMAFAIGVLGGEVALVGAAGAD-FADY-RDWLKARGVNCDHVLISETAHTAR 114 Query: 97 SCCIINNSNGNRTIVLHDTSLPDVS----ATDFEKVDLTQFKWIHIEGRNASEQVKMLQR 152 C + + ++ + A + + I A R Sbjct: 115 FTCTTDVDMAQIA-SFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPEAMFLHTEECR 173 Query: 153 IDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLY 212 P Q++ EE+ +L +F + L ++ + Sbjct: 174 KLGLAFAADPSQQL-----ARLSGEEIRRLVNGAAYLFTNDYEWDLLLSKTGWSEADVMA 228 Query: 213 GRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGR 272 + + V +G D + PDG +H P D G GD F A + S G Sbjct: 229 ----QIDLRVTTLGPKGVDLVEPDGTTIHVGVVPETSQTDPTGVGDAFRAGFLTGRSAGL 284 Query: 273 SVQEALRFGCQVAGKKCGLQG 293 ++ + + G VA G Sbjct: 285 GLERSAQLGSLVAVLVLESTG 305 >2ABQ-A nrPDB Length = 306 Score = 85.7 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 54/286 (18%), Positives = 111/286 (38%), Gaps = 16/286 (5%) Query: 14 LDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLV 73 +D I V+ + ++ R R Q GG N VL LG +G + G ++ Sbjct: 11 IDYIVQVENF-QQGVVNRSERDRKQPGGKGINVSRVLKRLGHETKALGFLG-GFTGAYVR 68 Query: 74 ADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQF 133 + + +S + +GDT + I G + L+ T+ P + + + Sbjct: 69 NALEKEEIGLSFIEV--EGDTRINVKI----KGKQETELNGTA-PLIKKEHVQALLEQLT 121 Query: 134 KWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQ-LFGYGDVVFVS 192 + + + V + + ++ V V+ E L + L + + Sbjct: 122 ELEKGDVLVLAGSVPQAMPQTIYRSMTQIAKERGAFVAVDTSGEALHEVLAAKPSFIKPN 181 Query: 193 KDVAKHLGFQ---SAEEALRGLYGRVRKGA-VLVCAWAEEGADALGPDGKLLHSDAFPPP 248 L + S E+A+ + + +G ++ ++A +GA +G H + P Sbjct: 182 HHELSELVSKPIASIEDAIPHVQRLIGEGIESILVSFAGDGALFASAEGM-FHVN-VPSG 239 Query: 249 RVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGF 294 V +++GAGD+ A + +L +G+S+++A+ F GF Sbjct: 240 EVRNSVGAGDSVVAGFLAALQEGKSLEDAVPFAVAAGSATAFSDGF 285 >2NWH-A nrPDB Length = 317 Score = 85.3 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 57/295 (19%), Positives = 110/295 (37%), Gaps = 19/295 (6%) Query: 4 KQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSM 63 K+IL +G +D +++ + S + GG N+ LS LG + Sbjct: 4 KKILVLGGAHIDRRGMIETETAPGAS-NPGSWMEEAGGGGFNAARNLSRLGFEVRIIAPR 62 Query: 64 APGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSL------ 117 + + R+ GV+ + + TPS I+ +GN I L D L Sbjct: 63 GGDVTGEVVAEAARQAGVEDTPFTF-LDRRTPSYTAILE-RDGNLVIALADMDLYKLFTP 120 Query: 118 PDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPRE 177 + + + ++ + + + L I A +P + K + Sbjct: 121 RRLKVRAVREAIIA-SDFLLCDANLPEDTLTALGLI-ARACEKPLAAIAISPAKAVKLKA 178 Query: 178 ELFQLFGYGDVVFVSKDVAKHLGFQSAEEAL--RGLYGRVRKGAVLVCAWAEEGADALGP 235 L + D++F+++ A+ L ++AE + + +V A E G Sbjct: 179 ALGDI----DILFMNEAEARALTGETAENVRDWPNILRKAGLSGGVVTRGASEVVAFNGT 234 Query: 236 DGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCG 290 + +LH V D GAGD + + ++++G++++EALR G A Sbjct: 235 EKAILHPPLIR--EVKDVTGAGDAMASGYLAAIAEGKTIREALRQGAAAAAITVQ 287 >3GO6-A nrPDB Length = 310 Score = 84.5 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 51/292 (17%), Positives = 85/292 (29%), Gaps = 30/292 (10%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 + VG V +D+ +VD P+ + S GG +N + GA F G+ Sbjct: 22 VCVVGSVNMDLTFVVDALPRPGETVLAASLTRTPGGKGANQAVAAARAGAQVQFSGAFGD 81 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDF 125 A L A R V + + + I+ +++ T+++ + ++ Sbjct: 82 DPAAAQLRAHLRANAVGLDRTVTVPG--PSGTAIIVVDASAENTVLVAPGANAHLTPV-- 137 Query: 126 EKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGY 185 + + + R + R L L Sbjct: 138 -PSAVANCDVLLTQLEIPVATALAAARAAQSADAVVMVNASPAGQD----RSSLQDLAAI 192 Query: 186 GDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAF 245 DVV ++ A V GA +G DG + A Sbjct: 193 ADVVIANEHEAN---------------DWPSPPTHFVITLGVRGARYVGADG-VFEVPA- 235 Query: 246 PPPRVVDTLGAGDTFNASVIFSLSQGRSVQE----ALRFGCQVAGKKCGLQG 293 P VDT GAGD F + + + ALR C + G Sbjct: 236 PTVTPVDTAGAGDVFAGVLAANWPRNPGSPAERLRALRRACAAGALATLVSG 287 >2QHP-A nrPDB Length = 296 Score = 80.7 bits (197), Expect = 8e-16, Method: Composition-based stats. Identities = 40/272 (14%), Positives = 91/272 (33%), Gaps = 25/272 (9%) Query: 37 WQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPS 96 + GG +N +S G + ++ + D ++ F+ + + D P+ Sbjct: 21 KKIGGAPANFAYHVSQFGFDSRVVSAVGNDELGDEIMEVFKEK----QLKNQIERVDYPT 76 Query: 97 SCCIINNSN-GNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHI-EGRNASEQVKMLQRID 154 + + G + + + D + ++ S + Sbjct: 77 GTVQVTLDDEGVPCYEIKEGVAW----DNIPFTDELKRLALNTRAVCFGSLAQRNEVSRA 132 Query: 155 AHNTRQPPEQKIRVSVEVE--------KPREELFQLFGYGDVVFVSKDVA----KHLGFQ 202 N I +++ +E L + F +++ ++ + + G+ Sbjct: 133 TINRFLDTMPDIDGQLKIFDINLRQDFYTKEVLRESFKRCNILKINDEELVTISRMFGYP 192 Query: 203 SAEEALRGLYGRVRKGA-VLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFN 261 + + + +L+ G+ P ++ P V DT+GAGD+F Sbjct: 193 GIDLQDKCWILLAKYNLKMLILTCGINGSYVFTPG--VVSFQETPKVPVADTVGAGDSFT 250 Query: 262 ASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 A+ S+ G+SV EA + +V+ C G Sbjct: 251 AAFCASILNGKSVPEAHKLAVEVSAYVCTQSG 282 >3I3Y-A nrPDB Length = 299 Score = 79.9 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 44/272 (16%), Positives = 91/272 (33%), Gaps = 34/272 (12%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 + G + +D + PK+ + I + GG +N +LS G + + Sbjct: 5 VYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATGN 64 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDT---PSSCCIINNSNGNRTIVLHDTSLPDVSA 122 ++ + + G + I+N+++G+ I+ + S Sbjct: 65 DSNGAWIRQQIKNE-----PLMLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSL 119 Query: 123 TDFEK--VDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELF 180 + D + +G + ++ + L + + + + Sbjct: 120 DEMIPHMADAVAGDILLQQGNFSLDKTRALFQ-------YARSRGMTTVFNPSPVNPDFC 172 Query: 181 QLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLL 240 L+ D+ V++ A+ L + LV GA L +G+ Sbjct: 173 HLWPLIDIAVVNESEAELLQPYGVK--------------TLVITQGAAGAW-LVQEGQRQ 217 Query: 241 HSDAFPPPRVVDTLGAGDTFNASVI-FSLSQG 271 A P +DT GAGDTF A ++ +L +G Sbjct: 218 FCPAVPA-EALDTTGAGDTFLAVMLASALLRG 248 >4E69-A nrPDB Length = 328 Score = 78.4 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 48/305 (15%), Positives = 96/305 (31%), Gaps = 31/305 (10%) Query: 5 QILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLL--GAPCAFMGS 62 IL +G + ++ P + R G+ N+ L+ L + ++ + Sbjct: 25 HILSIGECMAELAP--ADLPG--------TYRLGFAGDTFNTAWYLARLRPESRISYFSA 74 Query: 63 MAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDT--SLPDV 120 + ++ + A G+D + +I G R+ + ++ Sbjct: 75 IGDDALSQQMRAAMSAAGIDGGGLRVIPG--RTVGLYLITLEQGERSFAYWRGQSAAREL 132 Query: 121 SATDFEKVDLTQ-----------FKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVS 169 + + GR + R P + R+ Sbjct: 133 AGDADALAAAMARADVVYFSGITLAILDQCGRATLLRALAQARATGRTIAFDPNLRPRLW 192 Query: 170 VEVEKPREELFQLFGYGDVVFVS-KDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEE 228 + E + Q D+ S +D A G + + V+ Sbjct: 193 AGTGEMTETIMQGAAVSDIALPSFEDEAAWFGDAGPDATADRYARAGVRSVVV---KNGP 249 Query: 229 GADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKK 288 A DG+ P +VVDT AGD+FNA ++ S+ G+ ++ A+ +AG+ Sbjct: 250 HAVHFLQDGRRGRVPVPPVAQVVDTTAAGDSFNAGLLDSVLAGQPLETAIAAAAALAGQV 309 Query: 289 CGLQG 293 +G Sbjct: 310 VQGKG 314 >3KZH-A nrPDB Length = 328 Score = 75.3 bits (183), Expect = 3e-14, Method: Composition-based stats. Identities = 39/279 (13%), Positives = 85/279 (30%), Gaps = 10/279 (3%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 +L G V+DV + + + GG N ++ +G FM + Sbjct: 9 LLVFGASVVDVFGFSKASYRPYNST-PGHVKISFGGVCRNIAENMARVGVNTNFMSILGN 67 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSAT-- 123 +V ++ G + G TP+ I++ + + + S+ ++ Sbjct: 68 DEHGKSIVEHSKKIGYHMDDSMVIEGGSTPTYLAILDENGEMVSAIADMKSIGAMNTDFI 127 Query: 124 DFEKVDLTQFKWIHIEGRNASEQVKMLQRI-DAHNTRQPPEQKIRVSVEVEKPREELFQL 182 D ++ ++ ++ N +L+ D N P + S ++ F Sbjct: 128 DSKREIFENAEYTVLDSDNPEIMEYLLKNFKDKTNFILDPVSAEKASWVKHLIKD--FHT 185 Query: 183 FGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHS 242 +A G K + + + DG Sbjct: 186 IKPNRHEAEILAGFPITDTDDLIKASNYFLGLGIKKVFI----SLDADGIFYNDGVSCGK 241 Query: 243 DAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 V + GAGD+F A + + +++ ++F Sbjct: 242 IKATEVDVKNVTGAGDSFVAGLGYGYMNKMPIEDIVKFA 280 >2AFB-A nrPDB Length = 351 Score = 75.3 bits (183), Expect = 3e-14, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 95/299 (31%), Gaps = 42/299 (14%) Query: 31 RCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQS 90 + S GG +N L+ +G F+ + + D R+ GV +A Sbjct: 35 QTDSFDVTYGGAEANVAAFLAQMGLDAYFVTKLPNNPLGDAAAGHLRKFGVKTDYIA--- 91 Query: 91 KGDTPSSCCIINNSNGNR-TIVLHD---TSLPDVSATDFEKVDLTQ-FKWIHIEGRNA-- 143 +G + R + V++D +++ + DF+ + +W H G Sbjct: 92 RGGNRIGIYFLEIGASQRPSKVVYDRAHSAISEAKREDFDWEKILDGARWFHFSGITPPL 151 Query: 144 --------SEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDV 195 + +K+ + R+ + E + + Y DV+ +++ Sbjct: 152 GKELPLILEDALKVANEKGV-TVSCDLNYRARLWTKEEAQKVMI-PFMEYVDVLIANEED 209 Query: 196 AKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPR------ 249 + + S E L G++ + A A G L Sbjct: 210 IEKVLGISV-EGLDLKTGKLNREAYAKIAEEVTRKYNFKTVGITLRESISATVNYWSVMV 268 Query: 250 ---------------VVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 +VD +GAGD+F ++I+ G Q+ F + K + G Sbjct: 269 FENGQPHFSNRYEIHIVDRVGAGDSFAGALIYGSLMGFDSQKKAEFAAAASCLKHTIPG 327 >2AJR-A nrPDB Length = 331 Score = 74.1 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 51/269 (18%), Positives = 98/269 (36%), Gaps = 33/269 (12%) Query: 36 RWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTP 95 + GG N LS LG P G + G++ LV + R+ ++ +G+T Sbjct: 47 QMSPGGKGINVSIALSKLGVPSVATGFVG-GYMGKILVEELRKISKLITTNFVYVEGETR 105 Query: 96 SSCCIINNSNGNRTIVLHDTSLPDVSATDFE------KVDLTQFKWIHIEGRNASEQVKM 149 + II+ N T + PDV+ D K+ L++ + I G + Sbjct: 106 ENIEIIDEKNKTITAINFPG--PDVTDMDVNHFLRRYKMTLSKVDCVVISGSIPPGVNEG 163 Query: 150 -----LQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFV----SKDVAKHLG 200 ++ EQ R+ E +++ + +VV + + Sbjct: 164 ICNELVRLARERGVFVFVEQTPRL-------LERIYEGPEFPNVVKPDLRGNHASFLGVD 216 Query: 201 FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDT---LGAG 257 ++ ++ ++ K V V ++ + +G L +DT LGAG Sbjct: 217 LKTFDDYVKLAEKLAEKSQVSVVSYEVKNDIVATREGVWL----IRSKEEIDTSHLLGAG 272 Query: 258 DTFNASVIFSLSQ-GRSVQEALRFGCQVA 285 D + A +++ + G + E +FG A Sbjct: 273 DAYVAGMVYYFIKHGANFLEMAKFGFASA 301 >4GM6-A nrPDB Length = 351 Score = 73.8 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 45/274 (16%), Positives = 90/274 (32%), Gaps = 21/274 (7%) Query: 40 GGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQV--------AWQSK 91 GG +N LS LG P + + V R VD + V + + Sbjct: 56 GGAEANVAVNLSKLGHPTRIATVVPANPIGKMAVEHLWRHQVDTAFVVEAGDRLGTYYLE 115 Query: 92 GDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIE--GRNASEQVKM 149 T + + + H + D+S + + + I I VK+ Sbjct: 116 SGTALKAPSVVYDRQHSSFARHKSMDWDLS-ELLKGIRVLHVSGITIALSTFWLEMVVKI 174 Query: 150 LQRIDAHNTRQPPEQKIRVSV-EVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAE--E 206 ++ + + + R + E+E + QL D + A S+E + Sbjct: 175 IREAKRNGIKISFDMNYRAKLWELEAAKRAYQQLLPLVDYCSAGQMDAVAFFEISSETTD 234 Query: 207 ALRGLYGRVRKGAVLVCAWAEEGADALG-------PDGKLLHSDAFPPPRVVDTLGAGDT 259 + ++ + + + + G+ S+ + +VD +G GD Sbjct: 235 YYQAMHDKYPNIELFYATKRTVISASHHLLQGHLWTQGECWESEEYAIYPIVDRVGGGDA 294 Query: 260 FNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 + A+V+ + E ++F AG K + G Sbjct: 295 YTAAVLHGILSEWRPDETVKFATAAAGLKHSIHG 328 >3KD6-A nrPDB Length = 313 Score = 70.7 bits (171), Expect = 8e-13, Method: Composition-based stats. Identities = 52/267 (19%), Positives = 96/267 (35%), Gaps = 28/267 (10%) Query: 40 GGNASNSCTVLSLL-GAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSC 98 GG+++ S P +G + + + +D + G T Sbjct: 28 GGSSTYIALSASYFTDEPIRMVGVVGSDFGKEHF-DLLHAKNIDTRGIQVIEDGKTFRWA 86 Query: 99 CIINNSNGNRTIVLHDTSLPDVSA-TDFEKVDL---TQFKWIHIEGRNASEQVKMLQRID 154 + + DT ++ +F+ K++ + + Q+K+L +ID Sbjct: 87 GRYHYD-----MNTRDTLDTQLNVFAEFDPHVPQYYRDSKFVCLGNIDPELQLKVLDQID 141 Query: 155 AHNTRQPPEQKIRV--SVEVEKPREELFQLFGYGDVVFVSKDVAKHL-GFQSAEEALRGL 211 P+ + + +E EEL ++ DV V+ A+ L G + + R + Sbjct: 142 ------DPKLVVCDTMNFWIEGKPEELKKVLARVDVFIVNDSEARLLSGDPNLVKTARII 195 Query: 212 YGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQG 271 K L+ E GA +G + + AFP + D GAGDTF I L++ Sbjct: 196 REMGPKT--LIIKKGEHGALLFTDNG-IFAAPAFPLESIYDPTGAGDTFAGGFIGHLARC 252 Query: 272 RSVQE-----ALRFGCQVAGKKCGLQG 293 + E A+ +G +A G Sbjct: 253 GNTSEAEMRKAVLYGSAMASFCVEQFG 279 >4E84-A nrPDB Length = 352 Score = 69.9 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 54/300 (18%), Positives = 111/300 (37%), Gaps = 16/300 (5%) Query: 1 MEEKQILCVGLVVLDVI--SLVDKY-PKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPC 57 + ++L VG V+LD VD+ P+ + + ++ +R G A+N LG Sbjct: 51 LARSRVLVVGDVMLDRYWFGNVDRISPEAPVPVVHVQRQEERLGGAANVARNAVTLGGQA 110 Query: 58 AFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSL 117 + + + +V GV + P++ + + + + + ++ Sbjct: 111 GLLCVVGCDEPGERIVELLGSSGV-TPHLERDP--ALPTTIKLRVLARQQQLLRVDFEAM 167 Query: 118 PDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPRE 177 P + L +F + + + + H T + + + P+ Sbjct: 168 P---THEVLLAGLARFDVL-LPQHDVVLMSDYAKGGLTHVTTMIEKARAAGKAVLVDPKG 223 Query: 178 ELFQLFGYGDVVFVSKDVAKHLGFQ-SAEEALRGLYGRVR---KGAVLVCAWAEEGADAL 233 + + + ++ ++ + + Q +E+ LR +R L+ +EEG Sbjct: 224 DDWARYRGASLITPNRAELREVVGQWKSEDDLRARVANLRAELDIDALLLTRSEEGMTLF 283 Query: 234 GPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 G+ LH+ A V D GAGDT A+V L G + +A+ + AG G G Sbjct: 284 SAGGE-LHAPAL-AREVFDVSGAGDTVIATVATMLGAGVPLVDAVVLANRAAGIVVGKLG 341 >3N1C-A nrPDB Length = 309 Score = 60.7 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 49/277 (17%), Positives = 104/277 (37%), Gaps = 18/277 (6%) Query: 26 EDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQ 85 + ++RC + ++ GG N ++ LG + G + LV+ V V+ Sbjct: 24 PEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAG-GATGEHLVSLLADENVPVA- 81 Query: 86 VAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVS--ATDFEKVDLTQFKWIHIEGR-- 141 ++K T + + ++G + + + + E+V + I + Sbjct: 82 -TVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSL 140 Query: 142 NASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGF 201 +++ L ++ +Q IR V+ G ++V ++ L Sbjct: 141 PPGVKLEKLTQL----ISAAQKQGIRCIVDSSGEALSAALAIGNIELVKPNQKELSALVN 196 Query: 202 Q--SAEEALRGLYGRVR---KGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGA 256 + + + +R + K +V + +GA LG D + PP + T+GA Sbjct: 197 RELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGA--LGVDSENCIQVVPPPVKSQSTVGA 254 Query: 257 GDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 GD+ ++ L++ S++E +RFG QG Sbjct: 255 GDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQG 291 >2JG5-A nrPDB Length = 306 Score = 59.9 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 51/289 (17%), Positives = 103/289 (35%), Gaps = 35/289 (12%) Query: 14 LDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLV 73 +D + + + K D R + GG N VL L +G G F++ Sbjct: 11 IDYVIFTNDF-KIDGLNRATATYKFAGGKGINVSRVLKTLDVESTALGFAG-GFPGKFII 68 Query: 74 ADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKV----- 128 + + + + + G T + P +++T FE++ Sbjct: 69 DTLNNSAIQSNFIEVDED-----TRINVKLKTGQETEINAPG--PHITSTQFEQLLQQIK 121 Query: 129 DLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGY-GD 187 + T + + G S DA+ + + V+ +E + Y Sbjct: 122 NTTSEDIVIVAGSVPSS-----IPSDAYAQIAQITAQTGAKLVVDAEKELAESVLPYHPL 176 Query: 188 VVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAF-- 245 + +KD + + F + + + R +LV A+ +LG DG + Sbjct: 177 FIKPNKDELEVM-FNTTVNSDADVIKYGR---LLVDKGAQSVIVSLGGDGAIYIDKEISI 232 Query: 246 ----PPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCG 290 P +VV+T+G+GD+ A ++ ++ G S+++A + CG Sbjct: 233 KAVNPQGKVVNTVGSGDSTVAGMVAGIASGLSIEKAFQ-----QAVACG 276 >3KTN-A nrPDB Length = 346 Score = 58.7 bits (140), Expect = 3e-09, Method: Composition-based stats. Identities = 46/299 (15%), Positives = 92/299 (30%), Gaps = 30/299 (10%) Query: 24 PKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDV 83 P+ + R G N L+ A + + + + A R+ G+ Sbjct: 18 PEYLMLEQTEQLRMNFVGTGVNLLANLAHFQLETALITKLPANRLGEAGKAALRKLGISD 77 Query: 84 SQVAWQSK--GDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFE-KVDLTQFKWIHIEG 140 V + G + H ++ A D++ + L + +HI G Sbjct: 78 QWVGEKGDHIGSFFAEMGYGIRPTQVTYQNRHQSAFGISEAKDYDFEAFLAEVDMVHICG 137 Query: 141 RNASEQVKM-------LQRIDAHN----TRQPPEQKIRVSVEVEKPREELFQLFGYGDVV 189 + S K Q+ A+ + + R++ ++ Y D+V Sbjct: 138 ISLSLTEKTRDAALILAQKAHAYQKKVCFDFNYRPSLNTANSALFMRQQYERILPYCDIV 197 Query: 190 FVSKDVAKHL----------GFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKL 239 F S+ L G E ++ + + G L Sbjct: 198 FGSRRDLVELLGFIPREDLEGEAQETELIQRFMSQYNLEWFAGTTRSHSQNQNY-LSGYL 256 Query: 240 LHSDAFPPPRV-----VDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQG 293 + + +D +GAGD + A +++ SQ S+++A+ F +QG Sbjct: 257 YTQNEYQQSEKRPLLNLDRIGAGDAYAAGILYGYSQNWSLEKAVTFATVNGVLAHTIQG 315 >2AWD-A nrPDB Length = 323 Score = 56.8 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 47/294 (15%), Positives = 99/294 (33%), Gaps = 28/294 (9%) Query: 6 ILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAP 65 + +D+ L+D K D+ R GG N V+ LG G + Sbjct: 5 VTVTMNPSIDISYLLDHL-KLDTVNRTSQVTKTPGGKGLNVTRVIHDLGGDVIATGVLG- 62 Query: 66 GHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDF 125 G F+ + ++ + + + + + + I + I+ + P VS + Sbjct: 63 GFHGAFIANELKKANIPQAFTSIKEETRDSIA---ILHEGNQTEIL---EAGPTVSPEEI 116 Query: 126 E------KVDLTQFKWIHIEGRNASEQVKM-LQRIDAHNTRQPPEQKIRVSVEVEKPREE 178 + Q + + I G A Q + Q + + S + + + Sbjct: 117 SNFLENFDQLIKQAEIVTISGSLAKGLPSDFYQELVQKAHAQEVKVLLDTSGDSLR---Q 173 Query: 179 LFQLFGYGDVVFVSKDVAKHLGFQS-AEEALRGLYGRVRKGAVLVCAWAEEGADALGPDG 237 + Q ++ + + + L Q +E L + + K W +LG DG Sbjct: 174 VLQGPWKPYLIKPNLEELEGLLGQDFSENPLAAVQTALTKPMFAGIEWIV---ISLGKDG 230 Query: 238 KL------LHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVA 285 + + P + + +G+GD A + + L++ E L++G Sbjct: 231 AIAKHHDQFYRVKIPTIQAKNPVGSGDATIAGLAYGLAKDAPAAELLKWGMAAG 284 >3JUL-A nrPDB Length = 320 Score = 51.8 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 44/289 (15%), Positives = 89/289 (30%), Gaps = 18/289 (6%) Query: 11 LVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVAD 70 +D + + ++ R + + GG + VLS G +G ++ D Sbjct: 10 NPAIDRLLFIRGELEKRKTNRVIKTEFDCGGKGLHVSGVLSKFGIKNEALGIAGSDNL-D 68 Query: 71 FLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDL 130 L A + + ++ + + T + C + S+ + + VS T+ + + Sbjct: 69 KLYAILKEKHINHDFLV---EAGTSTRECFVVLSDDTNGSTMIPEAGFTVSQTNKDNLLK 125 Query: 131 TQFK-------WIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLF 183 K + + + + S E E+ Sbjct: 126 QIAKKVKKEDMVVIAGSPPPHYTLSDFKELLRTVKATGAFLGCDNSGEYLNLAVEM---- 181 Query: 184 GYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSD 243 D + ++D + + + K LV + +G+ +GKL Sbjct: 182 -GVDFIKPNEDEVIAILDEKTNSLEENIRTLAEKIPYLVVSLGAKGSICAH-NGKLYQVI 239 Query: 244 AFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQ 292 DT GAGD F + I L+ + E L+ + K Q Sbjct: 240 PPKVQERNDT-GAGDVFVGAFIAGLAMNMPITETLKVATGCSASKVMQQ 287 >5YSQ-A nrPDB Length = 286 Score = 47.6 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 48/264 (18%), Positives = 90/264 (34%), Gaps = 33/264 (12%) Query: 38 QRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSS 97 GG SLLG + V+ F + R GV+V + +P + Sbjct: 22 AYGGGVVMGAITSSLLGVKTKVITKCTREDVSKF--SFLRDNGVEVVFL------KSPRT 73 Query: 98 CCIIN--NSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIE----GRNASEQVKMLQ 151 I N S+ + ++ + +D + + + +HI G + + +L+ Sbjct: 74 TSIENRYGSDPDTRESFLISAADPFTESDLAFI---EGEAVHINPLWYGEFPEDLIPVLR 130 Query: 152 R------IDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAE 205 R DA + PE + V + E +E+ + V S++ G Sbjct: 131 RKVMFLSADAQGFVRVPENEKLVYRDWE-MKEKYLKYLDLFKVD--SREAETLTGTNDLR 187 Query: 206 EALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVI 265 E+ R + K + A D + +F + G GDT A+ + Sbjct: 188 ESCRIIRSFGAKIILATHASGVIVFDG------NFYEASFRSWSLEGRTGRGDTCTAAFL 241 Query: 266 FSLS-QGRSVQEALRFGCQVAGKK 288 + S+++A +F V K Sbjct: 242 VGFVFKKMSIEKATKFAAAVTSVK 265 >2I5B-A nrPDB Length = 271 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 52/147 (35%), Gaps = 12/147 (8%) Query: 144 SEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREEL---FQLFGYGDVVFVSKDVAKHL- 199 K ++ N P + + EV P QL V+ + A L Sbjct: 90 ELAAKTIKEKQLKNVVIDPVMVCKGANEVLYPEHAQALREQLAPLATVITPNLFEASQLS 149 Query: 200 ---GFQSAEEALRG---LYGRVRKGAVLVCAWA--EEGADALGPDGKLLHSDAFPPPRVV 251 ++ ++ + ++ + V+ E A + DG+ Sbjct: 150 GMDELKTVDDMIEAAKKIHALGAQYVVITGGGKLKHEKAVDVLYDGETAEVLESEMIDTP 209 Query: 252 DTLGAGDTFNASVIFSLSQGRSVQEAL 278 T GAG TF+A+V L++G V+EA+ Sbjct: 210 YTHGAGCTFSAAVTAELAKGAEVKEAI 236 >6C8Z-A nrPDB Length = 511 Score = 36.0 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 28/203 (13%), Positives = 60/203 (29%), Gaps = 18/203 (8%) Query: 70 DFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIV-LHDTSLPDVSATDFEKV 128 D + G+D +VA IV L++ ++ + E+V Sbjct: 319 DIVRKHVHSLGLDTVEVANALNVLGYEELAYSVIKKDENAIVALYEGAVILLHELKLERV 378 Query: 129 DLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDV 188 + + + D+ + + + + + V R L + D+ Sbjct: 379 HVHSLGY-----------YICVVSKDSPVSPEDHRKSLLFASTVAAARALLGNINSLDDI 427 Query: 189 VFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPP 248 G+ L L + + + E G ++ Sbjct: 428 EAGLDVPVSEQGY----NQLEKLEKYLVRRGICTLEDFENGCICTPNHD-VIIIPTKVVE 482 Query: 249 RVVDTLGAGDTF-NASVIFSLSQ 270 + V T+G GDT A+ + L++ Sbjct: 483 KPVATVGIGDTISAAAFVSVLAK 505 >4C5N-A nrPDB Length = 276 Score = 33.7 bits (75), Expect = 0.090, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 43/121 (35%), Gaps = 9/121 (7%) Query: 178 ELFQLFGYGDVVFVSKDVAKHLGF-------QSAEEALRGLYGRVRKGAVLVCAWA--EE 228 + L VV + A L + ++A ++ + + ++ A ++ Sbjct: 125 MIKYLLPKATVVTPNLFEAGQLSGLGKLNSIEDMKKAATIIFDKGAQHVIIKGGKALDQD 184 Query: 229 GADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKK 288 + L DG+ + + GAG TF A+ L+ G+S +EA+ Sbjct: 185 KSYDLYYDGQTFYQLTTDMFQQSYNHGAGCTFAAATTAYLANGKSPKEAVISAKAFVASA 244 Query: 289 C 289 Sbjct: 245 I 245 >3MBJ-A nrPDB Length = 291 Score = 33.3 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 26/135 (19%), Positives = 46/135 (34%), Gaps = 16/135 (11%) Query: 163 EQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHL---------GFQSAEEALRGLYG 213 ++ + ++E +E+ L DV+ + +L + +E LR L Sbjct: 118 NGRLYTNFDME-MVKEMRHLITKADVITPNLTELFYLLDEPYKADSTDEELKEYLRLLSD 176 Query: 214 RVRKGAVLVCAWA-----EEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSL 268 + + ++ + A G P G GDTF + + SL Sbjct: 177 KGPQVVIITSVPVHDEPHKTSVYAYNRQGNRYWKVTCPYLPAHYP-GTGDTFTSVITGSL 235 Query: 269 SQGRSVQEALRFGCQ 283 QG S+ AL Q Sbjct: 236 MQGDSLPMALDRATQ 250 >1TZ9-A nrPDB Length = 367 Score = 32.9 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 19/141 (13%), Positives = 52/141 (36%), Gaps = 11/141 (7%) Query: 49 VLSLLGAPCAFMG---SMAPGHVADFL------VADFRRRGVDVSQVAWQSKGDTPSSCC 99 L+LLG + ++ + + + G+ + +++ + Sbjct: 68 GLALLGIESVAIHDAIKAGTDQRDHYIDNYRQTLRNLGKCGISLVCYSFKPIFGWAKTDL 127 Query: 100 IINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEG--RNASEQVKMLQRIDAHN 157 N +G+ +++ + ++ D ++ +Q K + G +Q + L+ + A Sbjct: 128 AYENEDGSLSLLFDQAVVENMQPEDMYQLIHSQSKGFRLPGWEEERLQQFQELKAMYAGV 187 Query: 158 TRQPPEQKIRVSVEVEKPREE 178 T + + +R +E P E Sbjct: 188 TEEDLVENLRYFLERVIPVCE 208 >5ZWB-B nrPDB Length = 296 Score = 32.2 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 42/121 (34%), Gaps = 7/121 (5%) Query: 170 VEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQ---SAEEALRGLYGRVRKG---AVLVC 223 V+ E P+ L + + + L + + EEA+ + V+ Sbjct: 142 VQAEIPQAYRTHLLPQAQGLTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITS 201 Query: 224 AWAEEGADALGPDGKLLHSDAFPPPRVVDTL-GAGDTFNASVIFSLSQGRSVQEALRFGC 282 A E + F PRV L G GD F A ++ + QG+ + A + Sbjct: 202 APGESLETITVAVVTAQVVEVFAHPRVATELKGTGDLFCAELVSGIVQGKKLTTAAKDAA 261 Query: 283 Q 283 Q Sbjct: 262 Q 262 >4US5-D nrPDB Length = 338 Score = 31.8 bits (70), Expect = 0.34, Method: Composition-based stats. Identities = 21/118 (17%), Positives = 35/118 (29%), Gaps = 17/118 (14%) Query: 52 LLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCII--------NN 103 LG P A+ A F+ DF R +D + A+ DTPS I+ + Sbjct: 183 RLGLPYAY---------AHFITPDFTREAMDTYRAAFVPGPDTPSPRPILSVVVCCAETD 233 Query: 104 SNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQP 161 + R H +S D + ++ + + P Sbjct: 234 AEAQRVYATHRLFHRRMSQGDVRLLPPADLAVAEMDKPGPDPLAEESFEWPRYVVGSP 291 >2DDM-A nrPDB Length = 283 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 38/115 (33%), Gaps = 5/115 (4%) Query: 172 VEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGAD 231 E R+ L L ++ + + A+ + V + G + Sbjct: 142 PEAYRQYLLPLAQGITPNIFELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVVTSASGNE 201 Query: 232 ALGPDGKLL----HSDAFPPPRV-VDTLGAGDTFNASVIFSLSQGRSVQEALRFG 281 ++ + RV D G GD F A +I L +G+++ +A+ Sbjct: 202 ENQEMQVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALTDAVHRA 256 >5HX2-D nrPDB Length = 660 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 40/130 (30%), Gaps = 8/130 (6%) Query: 57 CAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCIINNSNGNRTIVLHDTS 116 ++G + P + ++ G D + S DT ++ +IN + + Sbjct: 254 ANYIGGLKPTQNSTIVIEYISTNGADANGAVGFSYADTLTNITVININENPNDDPDFVGA 313 Query: 117 LPDVSATDFEKV-------DLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVS 169 D E++ TQ + + + + I A T K + Sbjct: 314 DGGGDPEDIERIRELGTIKRETQQRCVTATDYDTFVSERFGSIIQAVQTFTD-STKPGYA 372 Query: 170 VEVEKPREEL 179 KP+ L Sbjct: 373 FIAAKPKSGL 382 >4XF7-A nrPDB Length = 273 Score = 30.2 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 19/68 (27%), Gaps = 3/68 (4%) Query: 218 GAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEA 277 +L+ E G L + GAGD F + SQ VQ Sbjct: 182 DVLLLSNGPEPGKAFLHGREYTFEPVHVGVDE---STGAGDVFLGAFTGFYSQCPFVQAL 238 Query: 278 LRFGCQVA 285 R A Sbjct: 239 KRAAAFTA 246 >1B9Y-C nrPDB Length = 246 Score = 29.8 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 26/169 (15%), Positives = 60/169 (35%), Gaps = 13/169 (7%) Query: 111 VLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTR----QPPEQKI 166 V++D + + D + + ++ + + S K + + + Q Sbjct: 25 VINDWRKFKLESEDGDSIPPSKKEILRQMSSPQSRDDKDSKERMSRKMSIQEYELIHQDK 84 Query: 167 RVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAW- 225 + K R + Q + + F + ++ E+ L + + ++V + Sbjct: 85 EDEGCLRKYRRQCMQDM-HQKLSFGPRYGF-VYELETGEQFLETIEKEQKVTTIVVNIYE 142 Query: 226 -AEEGADALGPDGKLLHSDAFPPPRVVD----TLGAGDTFNASVIFSLS 269 G DAL + L + +P + GAGD F++ V+ +L Sbjct: 143 DGVRGCDALNSSLECL-AAEYPMVKFCKIRASNTGAGDRFSSDVLPTLL 190 >4BJP-A nrPDB Length = 511 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 5/81 (6%), Positives = 20/81 (24%), Gaps = 9/81 (11%) Query: 28 SEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVA 87 + + + GG + + + P ++ ++ A Sbjct: 400 TVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPD--GRYINKY-------IAYTA 450 Query: 88 WQSKGDTPSSCCIINNSNGNR 108 + P ++ ++ Sbjct: 451 GVAPASQPRFALVVVINDPQA 471 >2D4W-A nrPDB Length = 504 Score = 28.7 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 27/98 (27%) Query: 176 REELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGP 235 R L L Y + +++ + FQS E L + L Sbjct: 362 RGALVGLTRYVNRNHIARAALEATAFQSREVVDAMNADSGVDLTELRVDGGMVANELLMQ 421 Query: 236 DGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRS 273 P+V +T G + A + +G Sbjct: 422 FQADQLGVDVVRPKVAETTALGAAYAAGIAVGFWKGEQ 459 >5GQ0-B nrPDB Length = 349 Score = 28.7 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 32/248 (12%), Positives = 66/248 (26%), Gaps = 23/248 (9%) Query: 35 QRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAW-QSKGD 93 + G S ++ +G G + D + + Q KGD Sbjct: 13 GQKGGTGPGPRSSHGIAAVGDKLYSFG--GELTPNKHIDKDLYVFDFNTQTWSIAQPKGD 70 Query: 94 TPSSCCI-INNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQR 152 P+ C+ + I + + + +F D +W + ++V + Sbjct: 71 APTVSCLGVRMVAVGTKIYIFGGRDENRNFENFRSYDTVTSEWTFLTK---LDEVGGPEA 127 Query: 153 IDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLGFQSAEEALRGLY 212 H+ E + V V K + + + + K + Sbjct: 128 RTFHSMASD-ENHVYVFGGVSK-GGTMNTPTRFRTIEAYNIADGKWA---QLPDPGDNFE 182 Query: 213 GRVRKGAVLVCAW-----------AEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFN 261 R G +V G D + + A V+T GA + Sbjct: 183 KRGGAGFAVVQGKIWVVYGFATSIVPGGKDDYESNAVQFYDPASKKWTEVETTGAKPSAR 242 Query: 262 ASVIFSLS 269 + ++ Sbjct: 243 SVFAHAVV 250 >1TD2-A nrPDB Length = 287 Score = 28.3 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 38/115 (33%), Gaps = 14/115 (12%) Query: 183 FGYGDVVFVSKDVAKHL------GFQSAEEALRGLYGRVRKGAVLVCAWAEEG------- 229 D++ + + L + A A R L + + VLV A G Sbjct: 137 LPASDIIAPNLVELEILCEHAVNNVEEAVLAARELIAQGPQ-IVLVKHLARAGYSRDRFE 195 Query: 230 ADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQV 284 + D S + +G GD + ++ L QG ++QEAL Sbjct: 196 MLLVTADEAWHISRPLVDFGMRQPVGVGDVTSGLLLVKLLQGATLQEALEHVTAA 250 >6GNG-A nrPDB Length = 612 Score = 28.3 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 18/51 (35%), Gaps = 7/51 (13%) Query: 33 LSQRWQRGGNASNSCTVLSLLGAPC-------AFMGSMAPGHVADFLVADF 76 + G A+N + + +G AF+G + AD +V Sbjct: 340 YTASSVDEGKAANKAVLQAEMGLKVSPTTPLIAFVGRLDDQKGADCMVEAM 390 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.117 0.261 Lambda K H 0.267 0.0358 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,926,463 Number of Sequences: 36641 Number of extensions: 325265 Number of successful extensions: 1126 Number of sequences better than 10.0: 79 Number of HSP's better than 10.0 without gapping: 99 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 937 Number of HSP's gapped (non-prelim): 147 length of query: 298 length of database: 10,336,785 effective HSP length: 96 effective length of query: 202 effective length of database: 6,819,249 effective search space: 1377488298 effective search space used: 1377488298 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.1 bits)