BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P49960 (444 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6ASO-A nrPDB 860 0.0 6AH0-4 nrPDB 58 6e-09 5MMM-v nrPDB 50 2e-06 6R5K-D nrPDB 48 9e-06 5ZWN-V nrPDB 39 0.006 3SXL-A nrPDB 37 0.018 2BZ2-A nrPDB 36 0.043 1X5P-A nrPDB 36 0.043 6GML-X nrPDB 35 0.049 4EGL-A nrPDB 35 0.085 5MQF-o nrPDB 34 0.11 2KU7-A nrPDB 34 0.11 2CQB-A nrPDB 34 0.11 3MDF-A nrPDB 34 0.12 2DGP-A nrPDB 33 0.22 4LMZ-A nrPDB 33 0.27 2VR2-A nrPDB 33 0.30 2DGQ-A nrPDB 32 0.38 2DH7-A nrPDB 32 0.42 5SZW-A nrPDB 32 0.54 4WKR-A nrPDB 31 0.86 5OSG-h nrPDB 31 0.97 4WWM-A nrPDB 30 1.5 1SGO-A nrPDB 30 1.5 2DIU-A nrPDB 30 2.0 4FXV-A nrPDB 30 2.0 3HI9-A nrPDB 30 2.3 2MYF-A nrPDB 30 2.4 2SXL-A nrPDB 30 3.0 1X4A-A nrPDB 30 3.0 1FXL-A nrPDB 29 3.4 2CPD-A nrPDB 29 4.0 2DH9-A nrPDB 29 4.5 6AHD-X nrPDB 29 5.2 1FNX-H nrPDB 28 9.0 >6ASO-A nrPDB Length = 424 Score = 860 bits (2223), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/417 (100%), Positives = 417/417 (100%) Query: 28 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEF 87 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEF Sbjct: 2 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEF 61 Query: 88 ARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSI 147 ARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSI Sbjct: 62 ARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSI 121 Query: 148 RLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATL 207 RLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATL Sbjct: 122 RLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATL 181 Query: 208 EGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE 267 EGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE Sbjct: 182 EGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE 241 Query: 268 RALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSL 327 RALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSL Sbjct: 242 RALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSL 301 Query: 328 ICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTI 387 ICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTI Sbjct: 302 ICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTI 361 Query: 388 NDMKRYYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE 444 NDMKRYYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE Sbjct: 362 NDMKRYYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE 418 >6AH0-4 nrPDB Length = 424 Score = 58.2 bits (139), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 50/156 (32%), Positives = 81/156 (51%), Gaps = 17/156 (10%) Query: 158 RRFAYIDVTSKEDARYCVEKLNGLKIEGYTL-VTKVSNPLEKSKRTDSATLEGREIMIRN 216 + + +++ S+EDA Y ++ +N +K+ G + V K S +K D G I I N Sbjct: 54 QGYGFVEFLSEEDADYAIKIMNMIKLYGKPIRVNKAS---AHNKNLDV----GANIFIGN 106 Query: 217 LSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNC--CAFMVFENKDSAERALQ-MN 273 L E+ DE LL ++F FG I + P ++ N AF+ F + D+++ A++ MN Sbjct: 107 LDPEI-DEKLLYDTFSAFGVI--LQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMN 163 Query: 274 RSLLGNREISVSLA---DKKPFLERNEVKRLLASRN 306 L NR I+VS A D K + +RLLA++N Sbjct: 164 GQYLCNRPITVSYAFKKDSKGERHGSAAERLLAAQN 199 >5MMM-v nrPDB Length = 260 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 45/180 (25%), Positives = 89/180 (49%), Gaps = 16/180 (8%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++ N P + +R ++++ + ++ + SRRF ++ + + EDA +EKL Sbjct: 86 LYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIEKL 145 Query: 179 NGLKIEGYTLVTKVSN-PLE-----KSKRTDSATLEG-REIMIRNLSTELLDENLLRESF 231 N +I G + ++ PLE ++ DS +E ++ I NL+ + +E LL++ F Sbjct: 146 NDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVESPYKVYIGNLAKTVTNE-LLKDFF 204 Query: 232 EGFGSIEKINI---PAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLA 287 G + + P K + F F+ F +++ E A+Q +N S+L ++I V+ A Sbjct: 205 SEKGKVLGAKVQRTPGTSKSNGF----GFVSFSSEEEVEAAIQALNNSVLEGQKIRVNKA 260 >6R5K-D nrPDB Length = 581 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 51/186 (27%), Positives = 87/186 (46%), Gaps = 18/186 (9%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 173 + +L++ + PS ++ ++ D+ I V+ SIR+ TS +AY++ E R Sbjct: 40 SSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAITKTSLGYAYVNFNDHEAGRK 98 Query: 174 CVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGR-EIMIRNLSTELLDENLLRESFE 232 +E+LN YT + + S+R S +G I I+NL + +D L ++F Sbjct: 99 AIEQLN------YTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPD-IDNKALYDTFS 151 Query: 233 GFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKKP 291 FG I I E+ + F+ FE + +A+ A+ +N LL +EI V+ P Sbjct: 152 VFGDILSSKI--ATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA-----P 204 Query: 292 FLERNE 297 L R E Sbjct: 205 HLSRKE 210 >5ZWN-V nrPDB Length = 523 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 8/59 (13%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL 270 + I LS+ L+ E+ LR F+ FG+I + IP G+ CC F+ + ++ SAE A+ Sbjct: 315 VFIGGLSS-LVTEDELRAYFQPFGTIVYVKIPVGK-------CCGFVQYVDRLSAEAAI 365 >3SXL-A nrPDB Length = 184 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 38/178 (21%), Positives = 79/178 (44%), Gaps = 12/178 (6%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 + L + P T R + L + I + + + S +A++D TS+ D++ Sbjct: 13 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRA 72 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 ++ LNG+ + L + P +S ++ + + NL + D+ L F + Sbjct: 73 IKVLNGITVRNKRLKVSYARPGGES-------IKDTNLYVTNLPRTITDDQ-LDTIFGKY 124 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLL---GNREISVSLADK 289 GSI + NI K AF+ + ++ A+ A+ +++ G++ +SV LA++ Sbjct: 125 GSIVQKNI-LRDKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEE 181 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 10/155 (6%) Query: 41 TTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRF--ARIEFARYDGALAAIT 98 T ++V LP+ ++Y F+ GPI + K + F A ++F + AI Sbjct: 15 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIK 74 Query: 99 KTHKVVGQNE-IIVSH-------LTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLP 150 + + +N+ + VS+ + + L++TN P + T + + + L Sbjct: 75 VLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILR 134 Query: 151 SLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEG 185 R A++ +E+A+ + LN + EG Sbjct: 135 DKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEG 169 >2BZ2-A nrPDB Length = 121 Score = 35.8 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 45/76 (59%), Gaps = 8/76 (10%) Query: 220 ELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLG 278 E + LLR +F FG+I +++ + CAF+ +E +SA++A+ ++N + + Sbjct: 47 EDMTPTLLRGAFSPFGNIIDLSMDPPRN-------CAFVTYEKMESADQAVAELNGTQVE 99 Query: 279 NREISVSLADKKPFLE 294 + ++ V++A K+P L+ Sbjct: 100 SVQLKVNIARKQPMLD 115 >1X5P-A nrPDB Length = 97 Score = 35.8 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 45/76 (59%), Gaps = 8/76 (10%) Query: 220 ELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLG 278 E + LLR +F FG+I +++ + CAF+ +E +SA++A+ ++N + + Sbjct: 23 EDMTPTLLRGAFSPFGNIIDLSMDPPRN-------CAFVTYEKMESADQAVAELNGTQVE 75 Query: 279 NREISVSLADKKPFLE 294 + ++ V++A K+P L+ Sbjct: 76 SVQLKVNIARKQPMLD 91 >6GML-X nrPDB Length = 404 Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 48/86 (55%), Gaps = 8/86 (9%) Query: 220 ELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLG 278 E + LLR +F FG+I +++ + CAF+ +E +SA++A+ ++N + + Sbjct: 293 EDMTPTLLRGAFSPFGNIIDLSMDPPRN-------CAFVTYEKMESADQAVAELNGTQVE 345 Query: 279 NREISVSLADKKPFLERNEVKRLLAS 304 + ++ V++A K+P L+ K + S Sbjct: 346 SVQLKVNIARKQPMLDAATGKSVWGS 371 >4EGL-A nrPDB Length = 177 Score = 34.7 bits (78), Expect = 0.085, Method: Compositional matrix adjust. Identities = 34/166 (20%), Positives = 68/166 (40%), Gaps = 19/166 (11%) Query: 105 GQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYID 164 G+ +IV++L P + TQ +R L I V + + S + +++ Sbjct: 1 GRTNLIVNYL----------PQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVN 50 Query: 165 VTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDE 224 + +DA + LNGL+++ T+ + P S ++ + I L + + Sbjct: 51 YVTAKDAERAINTLNGLRLQSKTIKVSYARP-------SSEVIKDANLYISGLPRTMTQK 103 Query: 225 NLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL 270 + + + F FG I + Q + AF+ F+ + AE A+ Sbjct: 104 D-VEDMFSRFGRIINSRVLVDQTT-GLSRGVAFIRFDKRSEAEEAI 147 Score = 31.6 bits (70), Expect = 0.77, Method: Compositional matrix adjust. Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 18/159 (11%) Query: 41 TTVLVKNLPKSYNQNKVYKYFKHCGPI-----IHVDVAD-SLKKNFRFARIEFARYDGAL 94 T ++V LP++ Q+++ F G + I VA SL F + + A Sbjct: 3 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGF----VNYVTAKDAE 58 Query: 95 AAITKTHKVVGQNEII-VSH-------LTECTLWMTNFPPSYTQRNIRDLLQDINVVALS 146 AI + + Q++ I VS+ + + L+++ P + TQ+++ D+ + S Sbjct: 59 RAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINS 118 Query: 147 IRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEG 185 L SR A+I + +A + NG K G Sbjct: 119 RVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPG 157 >5MQF-o nrPDB Length = 301 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 9/82 (10%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIP---AGQKEHSFNNCCAFMVFENKDSA 266 R + + L+ E+ D+ +L +F FG I I IP +K F AF+ FE + A Sbjct: 6 RVLYVGGLAEEV-DDKVLHAAFIPFGDITDIQIPLDYETEKHRGF----AFVEFELAEDA 60 Query: 267 ERALQ-MNRSLLGNREISVSLA 287 A+ MN S L R I V+LA Sbjct: 61 AAAIDNMNESELFGRTIRVNLA 82 >2KU7-A nrPDB Length = 140 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 9/82 (10%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIP---AGQKEHSFNNCCAFMVFENKDSA 266 R + + L+ E+ D+ +L +F FG I I IP +K F AF+ FE + A Sbjct: 64 RVLYVGGLAEEV-DDKVLHAAFIPFGDITDIQIPLDYETEKHRGF----AFVEFELAEDA 118 Query: 267 ERALQ-MNRSLLGNREISVSLA 287 A+ MN S L R I V+LA Sbjct: 119 AAAIDNMNESELFGRTIRVNLA 140 >2CQB-A nrPDB Length = 102 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 8/72 (11%) Query: 220 ELLDENLLRESFEGFGSIEKINIP---AGQKEHSFNNCCAFMVFENKDSAERAL-QMNRS 275 E +D+ +L +F FG I I IP +K F AF+ FE + A A+ MN S Sbjct: 22 EEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGF----AFVEFELAEDAAAAIDNMNES 77 Query: 276 LLGNREISVSLA 287 L R I V+LA Sbjct: 78 ELFGRTIRVNLA 89 >3MDF-A nrPDB Length = 85 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 27/72 (37%), Positives = 36/72 (50%), Gaps = 8/72 (11%) Query: 220 ELLDENLLRESFEGFGSIEKINIP---AGQKEHSFNNCCAFMVFENKDSAERAL-QMNRS 275 E +D+ +L +F FG I I IP +K F AF+ FE + A A+ MN S Sbjct: 17 EEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGF----AFVEFELAEDAAAAIDNMNES 72 Query: 276 LLGNREISVSLA 287 L R I V+LA Sbjct: 73 ELFGRTIRVNLA 84 >2DGP-A nrPDB Length = 106 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 5/71 (7%) Query: 222 LDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDS---AERALQMNRSLLG 278 LDE L+ FE FG I ++ + + + CAF+ + ++S A+ AL ++L G Sbjct: 25 LDEKDLKPLFEEFGKIYELTV-LKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPG 83 Query: 279 -NREISVSLAD 288 NR I V AD Sbjct: 84 MNRPIQVKPAD 94 >4LMZ-A nrPDB Length = 180 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 37/178 (20%), Positives = 82/178 (46%), Gaps = 16/178 (8%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVAL--SIRLPSLRFNTSRRFAYIDVTSKEDARYCVE 176 +++ P S++++ +++L + V +R S S+ ++ +++ A Sbjct: 11 MFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 70 Query: 177 KLNGLKIEGYTLVTKVSNPLE--KSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 L+ +K + + +P++ + S +E R++ I +S + +EN +R F F Sbjct: 71 ALHNIKT-----LPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKC-NENDIRVMFSPF 124 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE---RALQMNRSLLG-NREISVSLAD 288 G IE+ I G + CAF+ F + A+ +A+ ++++ G + I V AD Sbjct: 125 GQIEECRILRG--PDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFAD 180 >2VR2-A nrPDB Length = 541 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 13/102 (12%) Query: 340 EKDIRKILLVSDFNGAI-IIFRDSKFAAKMLMIL--NGSQFQGKVIRSGTINDMKRYYNN 396 E +R I + S N + I+ SK AAK++ +G G+ I + D Y+N Sbjct: 250 EATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNK 309 Query: 397 QQNHSMKHVKPSCINMMEKGPNLQVKKKIPD-KQEQMSNDDF 437 + +H+ HV GP L+ PD ++NDD Sbjct: 310 EWHHAAHHV---------MGPPLRPDPSTPDFLMNLLANDDL 342 >2DGQ-A nrPDB Length = 108 Score = 32.3 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 222 LDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDS---AERALQMNRSLLG 278 LDE L+ FE FG I ++ + + + CAF+ + +DS A+ AL ++L G Sbjct: 27 LDEQDLKPLFEEFGRIYELTV-LKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPG 85 Query: 279 -NREISVSLA 287 NR I V A Sbjct: 86 MNRPIQVKPA 95 >2DH7-A nrPDB Length = 105 Score = 32.3 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 9/84 (10%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIP---AGQKEHSFNNCCAFMVFENKDSAER 268 + + +LS E+ E++ + +F FG I + A K + F+ F NK AE Sbjct: 18 VFVGDLSPEITTEDI-KSAFAPFGKISDARVVKDMATGKSKGY----GFVSFYNKLDAEN 72 Query: 269 AL-QMNRSLLGNREISVSLADKKP 291 A+ M LG R+I + A +KP Sbjct: 73 AIVHMGGQWLGGRQIRTNWATRKP 96 >5SZW-A nrPDB Length = 101 Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust. Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 10/92 (10%) Query: 104 VGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYI 163 +G+ +IV++L P + TQ +R L I V + + S + ++ Sbjct: 19 IGRTNLIVNYL----------PQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFV 68 Query: 164 DVTSKEDARYCVEKLNGLKIEGYTLVTKVSNP 195 + + +DA + LNGL+++ T+ + P Sbjct: 69 NYVTAKDAERAINTLNGLRLQSKTIKVSYARP 100 >4WKR-A nrPDB Length = 208 Score = 31.2 bits (69), Expect = 0.86, Method: Compositional matrix adjust. Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 2/58 (3%) Query: 42 TVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVA--DSLKKNFRFARIEFARYDGALAAI 97 TV V+ LPK+ N + + + F CG ++++ + S FA +EF + A AI Sbjct: 126 TVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAI 183 >5OSG-h nrPDB Length = 235 Score = 31.2 bits (69), Expect = 0.97, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 8/79 (10%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 + C F PS T+ + +L + V RL R N FAY + S A+ Sbjct: 135 SSCVFVSPIFRPSTTKAQVMELFAGVKVQ----RLRMYRQN----FAYAYLDSPAAAKKF 186 Query: 175 VEKLNGLKIEGYTLVTKVS 193 VE+ NG G+TL +S Sbjct: 187 VEEKNGTAFRGHTLRVALS 205 >4WWM-A nrPDB Length = 91 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 39/63 (61%), Gaps = 2/63 (3%) Query: 327 LICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGT 386 LI QF EI++N++++ ++L+ D +I+ ++ + +L+++NG + ++ R+ Sbjct: 10 LISQFNFREIYVNDRELLRVLVKIDSKKHLILNESNQLKSGILILINGKDW--RLYRNQL 67 Query: 387 IND 389 +ND Sbjct: 68 LND 70 >1SGO-A nrPDB Length = 139 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 15/29 (51%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Query: 161 AYIDVTSKEDARYCVEKLN-GLKIEGYTL 188 AYI+V +KE RYC+E GLK+ GY Sbjct: 64 AYINVETKERNRYCLELTEAGLKVVGYAF 92 >2DIU-A nrPDB Length = 96 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%) Query: 237 IEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQM--NRSLLGNREI 282 + +++ G K S C A + F N+DSAERA + N + GNR I Sbjct: 30 LRRLSDNCGGKVLSITGCSAILRFINQDSAERAQKRMENEDVFGNRII 77 >4FXV-A nrPDB Length = 99 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 17/83 (20%), Positives = 35/83 (42%) Query: 113 HLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDAR 172 + L + P + TQ +R L I V + + S + +++ + +DA Sbjct: 16 YFQGTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75 Query: 173 YCVEKLNGLKIEGYTLVTKVSNP 195 + LNGL+++ T+ + P Sbjct: 76 RAINTLNGLRLQSKTIKVSYARP 98 >3HI9-A nrPDB Length = 84 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 20/91 (21%), Positives = 40/91 (43%), Gaps = 10/91 (10%) Query: 105 GQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYID 164 G+ +IV++L P + TQ +R L I V + + S + +++ Sbjct: 3 GRTNLIVNYL----------PQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVN 52 Query: 165 VTSKEDARYCVEKLNGLKIEGYTLVTKVSNP 195 + +DA + LNGL+++ T+ + P Sbjct: 53 YVTAKDAERAINTLNGLRLQSKTIKVSYARP 83 >2MYF-A nrPDB Length = 89 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Query: 220 ELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLG 278 E +DE L + F FG I I +P N AF+ + D A+ AL MN L Sbjct: 20 ETIDEKSLYDIFSSFGDIRNIEVPLNMTTKK-NRGFAFVEYVEVDDAKHALYNMNNFELN 78 Query: 279 NREISVSLA 287 + I V+ + Sbjct: 79 GKRIHVNYS 87 >2SXL-A nrPDB Length = 88 Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 35/81 (43%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 + L + P T R + L + I + + + S +A++D TS+ D++ Sbjct: 2 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRA 61 Query: 175 VEKLNGLKIEGYTLVTKVSNP 195 ++ LNG+ + L + P Sbjct: 62 IKVLNGITVRNKRLKVSYARP 82 >1X4A-A nrPDB Length = 109 Score = 29.6 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 3/73 (4%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 +C +++ N PP ++I D+ + I L + R FA+++ DA V Sbjct: 22 DCRIYVGNLPPDIRTKDIEDVFYKYGAIR-DIDLKNRRGGPP--FAFVEFEDPRDAEDAV 78 Query: 176 EKLNGLKIEGYTL 188 +G +GY L Sbjct: 79 YGRDGYDYDGYRL 91 >1FXL-A nrPDB Length = 167 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 30/157 (19%), Positives = 62/157 (39%), Gaps = 9/157 (5%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 ++ L + P + TQ R L I + + S + +++ +DA Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 + LNGL+++ T+ + P SA++ + + L + + + L + F + Sbjct: 61 INTLNGLRLQTKTIKVSYARP-------SSASIRDANLYVSGLP-KTMTQKELEQLFSQY 112 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 G I I Q + F+ F+ + AE A++ Sbjct: 113 GRIITSRILVDQV-TGVSRGVGFIRFDKRIEAEEAIK 148 >2CPD-A nrPDB Length = 99 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 12/46 (26%), Positives = 27/46 (58%) Query: 153 RFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEK 198 R R +A++ +++EDA ++ LNG ++G + ++ P++K Sbjct: 46 RVKKIRDYAFVHFSNREDAVEAMKALNGKVLDGSPIEVTLAKPVDK 91 >2DH9-A nrPDB Length = 89 Score = 28.9 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 5/76 (6%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 I +RNL + +L++ F G + +I + E+ + C + FE+ + AERA + Sbjct: 8 IFVRNLPFDF-TWKMLKDKFNECGHVLYADI---KMENGKSKGCGVVKFESPEVAERACR 63 Query: 272 -MNRSLLGNREISVSL 286 MN L REI V + Sbjct: 64 MMNGMKLSGREIDVRI 79 >6AHD-X nrPDB Length = 376 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 24/45 (53%) Query: 267 ERALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELE 311 E+++Q SL N E S +L P+ E E+K+ + S +LE Sbjct: 269 EKSIQKQNSLGSNEEKSKTLKKSNPYGEWQEIKQEVESHEEVDLE 313 >1FNX-H nrPDB Length = 174 Score = 28.1 bits (61), Expect = 9.0, Method: Compositional matrix adjust. Identities = 29/157 (18%), Positives = 62/157 (39%), Gaps = 9/157 (5%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 ++ L + P + TQ + L I + + S + +++ + DA Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 + LNGLK++ T+ + P SA++ + + L + + + + + F + Sbjct: 63 INTLNGLKLQTKTIKVSYARP-------SSASIRDANLYVSGLP-KTMSQKEMEQLFSQY 114 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 G I I Q + F+ F+ + AE A++ Sbjct: 115 GRIITSRILLDQ-ATGVSRGVGFIRFDKRIEAEEAIK 150 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6ASO-A nrPDB 746 0.0 6R5K-D nrPDB 202 2e-52 5MMM-v nrPDB 188 5e-48 6AH0-4 nrPDB 180 1e-45 Sequences not found previously or not previously below threshold: 4EGL-A nrPDB 91 9e-19 1FNX-H nrPDB 89 3e-18 1FXL-A nrPDB 88 7e-18 5ZWM-4 nrPDB 87 2e-17 3SXL-A nrPDB 82 3e-16 5EN1-A nrPDB 75 7e-14 2CJK-A nrPDB 74 2e-13 4LMZ-A nrPDB 69 3e-12 5ZWN-V nrPDB 66 4e-11 3NNA-A nrPDB 65 8e-11 4FXV-A nrPDB 63 3e-10 5SZW-A nrPDB 63 3e-10 3HI9-A nrPDB 63 3e-10 1D8Z-A nrPDB 61 1e-09 2DH7-A nrPDB 60 2e-09 2MYF-A nrPDB 56 4e-08 2SXL-A nrPDB 55 7e-08 1P1T-A nrPDB 55 7e-08 5EV3-A nrPDB 54 2e-07 1SXL-A nrPDB 53 2e-07 5MQF-o nrPDB 53 3e-07 1X5O-A nrPDB 52 5e-07 4ZKA-A nrPDB 52 5e-07 3MDF-A nrPDB 52 5e-07 2KU7-A nrPDB 52 6e-07 2CQB-A nrPDB 52 6e-07 2DH9-A nrPDB 52 7e-07 2DGS-A nrPDB 52 7e-07 2YWK-A nrPDB 51 9e-07 2CQ3-A nrPDB 50 2e-06 1D9A-A nrPDB 50 3e-06 6D0Y-A nrPDB 49 4e-06 5OO6-B nrPDB 49 4e-06 5ZWM-X nrPDB 49 5e-06 2ERR-A nrPDB 49 6e-06 1H6K-X nrPDB 47 1e-05 2MGZ-B nrPDB 47 2e-05 2HYI-B nrPDB 47 2e-05 1P27-B nrPDB 47 2e-05 5YZG-w nrPDB 46 3e-05 3EX7-B nrPDB 46 3e-05 2J0Q-D nrPDB 46 3e-05 6QX9-R nrPDB 45 7e-05 6FEC-u nrPDB 44 1e-04 6QX9-1K nrPDB 43 2e-04 3CW1-K nrPDB 43 2e-04 2LEC-A nrPDB 43 2e-04 2KN4-A nrPDB 43 2e-04 4PKD-B nrPDB 43 2e-04 6GML-X nrPDB 43 2e-04 2RS2-A nrPDB 43 3e-04 1OO0-B nrPDB 42 4e-04 1RK8-A nrPDB 42 4e-04 5X3Y-A nrPDB 42 7e-04 1X4A-A nrPDB 41 0.001 6GD1-A nrPDB 41 0.001 6EM1-o nrPDB 41 0.001 2LXI-A nrPDB 41 0.001 2DH8-A nrPDB 40 0.001 2DGP-A nrPDB 40 0.001 4WKR-A nrPDB 40 0.002 1UAW-A nrPDB 40 0.002 2BZ2-A nrPDB 40 0.002 2MST-A nrPDB 40 0.003 2XS5-A nrPDB 40 0.003 2XS2-A nrPDB 40 0.003 1X5P-A nrPDB 40 0.003 2CPD-A nrPDB 39 0.003 6C8U-1 nrPDB 39 0.004 2EVZ-A nrPDB 38 0.011 1QM9-A nrPDB 37 0.011 2DGQ-A nrPDB 37 0.012 5YVG-X nrPDB 37 0.014 2KVI-A nrPDB 37 0.017 3NNH-A nrPDB 37 0.020 6FYY-r nrPDB 37 0.021 2XNQ-A nrPDB 37 0.021 6G90-B nrPDB 37 0.023 5ZWN-Q nrPDB 36 0.029 6QX9-1A nrPDB 36 0.030 2RT3-A nrPDB 36 0.031 1JMT-A nrPDB 36 0.036 4CQ1-A nrPDB 35 0.045 2DO0-A nrPDB 35 0.052 4WWM-A nrPDB 35 0.077 3P6Y-C nrPDB 35 0.082 2LCW-A nrPDB 35 0.090 2CQH-A nrPDB 35 0.091 2LA6-A nrPDB 34 0.15 6D6V-H nrPDB 34 0.15 2MMY-A nrPDB 34 0.19 2I2Y-A nrPDB 33 0.22 2LKZ-A nrPDB 33 0.25 2F9J-A nrPDB 33 0.28 1J4G-A nrPDB 32 0.38 3JB9-Y nrPDB 32 0.46 3GM8-A nrPDB 32 0.69 5MDU-A nrPDB 32 0.74 2MKI-A nrPDB 31 0.83 5WSG-X nrPDB 31 1.1 2M2B-A nrPDB 30 1.6 2CPE-A nrPDB 30 1.7 2VR2-A nrPDB 30 2.5 5OSG-h nrPDB 30 2.9 1UM9-A nrPDB 29 4.0 4YEW-A nrPDB 29 4.6 6FYY-p nrPDB 28 6.9 3NS5-A nrPDB 28 6.9 4NOX-A nrPDB 28 8.9 >6ASO-A nrPDB Length = 424 Score = 746 bits (1925), Expect = 0.0, Method: Composition-based stats. Identities = 417/417 (100%), Positives = 417/417 (100%) Query: 28 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEF 87 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEF Sbjct: 2 KKANEALTRNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRFARIEF 61 Query: 88 ARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSI 147 ARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSI Sbjct: 62 ARYDGALAAITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSI 121 Query: 148 RLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATL 207 RLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATL Sbjct: 122 RLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATL 181 Query: 208 EGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE 267 EGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE Sbjct: 182 EGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAE 241 Query: 268 RALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSL 327 RALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSL Sbjct: 242 RALQMNRSLLGNREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKVSPSL 301 Query: 328 ICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTI 387 ICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTI Sbjct: 302 ICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGTI 361 Query: 388 NDMKRYYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE 444 NDMKRYYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE Sbjct: 362 NDMKRYYNNQQNHSMKHVKPSCINMMEKGPNLQVKKKIPDKQEQMSNDDFRKMFLGE 418 >6R5K-D nrPDB Length = 581 Score = 202 bits (514), Expect = 2e-52, Method: Composition-based stats. Identities = 51/186 (27%), Positives = 87/186 (46%), Gaps = 18/186 (9%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 173 + +L++ + PS ++ ++ D+ I V+ SIR+ TS +AY++ E R Sbjct: 40 SSASLYVGDLEPSVSEAHLYDIFSPIGSVS-SIRVCRDAITKTSLGYAYVNFNDHEAGRK 98 Query: 174 CVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGR-EIMIRNLSTELLDENLLRESFE 232 +E+LN YT + + S+R S +G I I+NL ++ D L ++F Sbjct: 99 AIEQLN------YTPIKGRLCRIMWSQRDPSLRKKGSGNIFIKNLHPDI-DNKALYDTFS 151 Query: 233 GFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKKP 291 FG I I E+ + F+ FE + +A+ A+ +N LL +EI V+ P Sbjct: 152 VFGDILSSKI--ATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVA-----P 204 Query: 292 FLERNE 297 L R E Sbjct: 205 HLSRKE 210 Score = 112 bits (280), Expect = 3e-25, Method: Composition-based stats. Identities = 60/300 (20%), Positives = 118/300 (39%), Gaps = 34/300 (11%) Query: 36 RNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVA-DSLKKNFRFARIEFARYDGAL 94 R + + +KNL + +Y F G I+ +A D K+ F + F A Sbjct: 125 RKKGSGNIFIKNLHPDIDNKALYDTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAK 184 Query: 95 AAITKTHKVV--GQNEIIVSHLTE--------------CTLWMTNFPPSYTQRNIRDLLQ 138 AI + ++ GQ + HL+ L++ N T ++L Sbjct: 185 EAIDALNGMLLNGQEIYVAPHLSRKERDSQLEETKAHYTNLYVKNINSETTDEQFQELFA 244 Query: 139 DINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNP--- 195 + +S L + F +++ EDA VE LN ++ G L + Sbjct: 245 KFGPI-VSASLEKDADGKLKGFGFVNYEKHEDAVKAVEALNDSELNGEKLYVGRAQKKNE 303 Query: 196 --------LEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQK 247 E + A +G + ++NL + DE L E F +G+I + Sbjct: 304 RMHVLKKQYEAYRLEKMAKYQGVNLFVKNLDDSVDDEK-LEEEFAPYGTITSAKVMRT-- 360 Query: 248 EHSFNNCCAFMVFENKDSAERAL-QMNRSLLGNREISVSLADKKPFLERNEVKRLLASRN 306 E+ + F+ F + A +A+ + N+ ++ + + V++A +K + R+++ + + +RN Sbjct: 361 ENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRK-DVRRSQLAQQIQARN 419 >5MMM-v nrPDB Length = 260 Score = 188 bits (477), Expect = 5e-48, Method: Composition-based stats. Identities = 42/180 (23%), Positives = 87/180 (48%), Gaps = 16/180 (8%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++ N P + +R ++++ + ++ + SRRF ++ + + EDA +EKL Sbjct: 86 LYVGNIPRNLNNDELRTIVEEHGAIEIAEVMYDKYSGRSRRFGFVTMKTVEDANAVIEKL 145 Query: 179 NGLKIEGYTLVTKVSNP------LEKSKRTDSATLEG-REIMIRNLSTELLDENLLRESF 231 N +I G + ++ + ++ DS +E ++ I NL+ + +E LL++ F Sbjct: 146 NDTEIGGRKIKVNITEKPLEGMDIATTQAEDSQFVESPYKVYIGNLAKTVTNE-LLKDFF 204 Query: 232 EGFGSIEKINI---PAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLA 287 G + + P K + F F+ F +++ E A+Q +N S+L ++I V+ A Sbjct: 205 SEKGKVLGAKVQRTPGTSKSNGF----GFVSFSSEEEVEAAIQALNNSVLEGQKIRVNKA 260 >6AH0-4 nrPDB Length = 424 Score = 180 bits (456), Expect = 1e-45, Method: Composition-based stats. Identities = 50/197 (25%), Positives = 91/197 (46%), Gaps = 15/197 (7%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 + T+++ ++ + +L V + + + +++ S+EDA Y + Sbjct: 12 DATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAI 71 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFG 235 + +N +K+ G + ++ +K D G I I NL E+ DE LL ++F FG Sbjct: 72 KIMNMIKLYGKPIRVNKAS--AHNKNLDV----GANIFIGNLDPEI-DEKLLYDTFSAFG 124 Query: 236 SIEKINIPAGQKEHSFNN--CCAFMVFENKDSAERALQ-MNRSLLGNREISVSLA---DK 289 I P ++ N AF+ F + D+++ A++ MN L NR I+VS A D Sbjct: 125 VIL--QTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAFKKDS 182 Query: 290 KPFLERNEVKRLLASRN 306 K + +RLLA++N Sbjct: 183 KGERHGSAAERLLAAQN 199 >4EGL-A nrPDB Length = 177 Score = 90.9 bits (224), Expect = 9e-19, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 66/173 (38%), Gaps = 12/173 (6%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 L + P + TQ +R L I V + + S + +++ + +DA + Sbjct: 4 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 63 Query: 178 LNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSI 237 LNGL+++ T+ + P S ++ + I L + + + + F FG I Sbjct: 64 LNGLRLQSKTIKVSYARP-------SSEVIKDANLYISGL-PRTMTQKDVEDMFSRFGRI 115 Query: 238 EKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLGN--REISVSLA 287 + + + AF+ F+ + AE A+ N I+V A Sbjct: 116 INSRV-LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFA 167 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 34/169 (20%), Positives = 70/169 (41%), Gaps = 12/169 (7%) Query: 41 TTVLVKNLPKSYNQNKVYKYFKHCGPIIHVD-VADSLK-KNFRFARIEFARYDGALAAIT 98 T ++V LP++ Q+++ F G + + D + + + + + A AI Sbjct: 3 TNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAIN 62 Query: 99 KTHKVVGQNEII-VSH-------LTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLP 150 + + Q++ I VS+ + + L+++ P + TQ+++ D+ + S L Sbjct: 63 TLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVLV 122 Query: 151 SLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEG--YTLVTKVSNPLE 197 SR A+I + +A + NG K G + K + LE Sbjct: 123 DQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANLE 171 >1FNX-H nrPDB Length = 174 Score = 89.4 bits (220), Expect = 3e-18, Method: Composition-based stats. Identities = 33/178 (18%), Positives = 70/178 (39%), Gaps = 12/178 (6%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 ++ L + P + TQ + L I + + S + +++ + DA Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 + LNGLK++ T+ + P SA++ + + L + + + + + F + Sbjct: 63 INTLNGLKLQTKTIKVSYARP-------SSASIRDANLYVSGL-PKTMSQKEMEQLFSQY 114 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRS--LLGNREISVSLADK 289 G I I + + F+ F+ + AE A++ +N L I+V A+ Sbjct: 115 GRIITSRI-LLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANN 171 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 65/155 (41%), Gaps = 10/155 (6%) Query: 41 TTVLVKNLPKSYNQNKVYKYFKHCGPIIHVD-VADSLK-KNFRFARIEFARYDGALAAIT 98 T ++V LP++ Q++ F G I V D + ++ + + ++ + A AI Sbjct: 5 TNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAIN 64 Query: 99 KTHKVVGQNEII-VSH-------LTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLP 150 + + Q + I VS+ + + L+++ P + +Q+ + L + S L Sbjct: 65 TLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILL 124 Query: 151 SLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEG 185 SR +I + +A ++ LNG K G Sbjct: 125 DQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLG 159 >1FXL-A nrPDB Length = 167 Score = 88.2 bits (217), Expect = 7e-18, Method: Composition-based stats. Identities = 33/176 (18%), Positives = 68/176 (38%), Gaps = 12/176 (6%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 ++ L + P + TQ R L I + + S + +++ +DA Sbjct: 1 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 60 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 + LNGL+++ T+ + P SA++ + + L + + + L + F + Sbjct: 61 INTLNGLRLQTKTIKVSYARP-------SSASIRDANLYVSGL-PKTMTQKELEQLFSQY 112 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGN--REISVSLA 287 G I I + + F+ F+ + AE A++ +N I+V A Sbjct: 113 GRIITSRI-LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFA 167 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 63/157 (40%), Gaps = 10/157 (6%) Query: 41 TTVLVKNLPKSYNQNKVYKYFKHCGPIIHVD-VADSLK-KNFRFARIEFARYDGALAAIT 98 T ++V LP++ Q + F G I V D + ++ + + + A AI Sbjct: 3 TNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAIN 62 Query: 99 KTHKVVGQNEII-VSH-------LTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLP 150 + + Q + I VS+ + + L+++ P + TQ+ + L + S L Sbjct: 63 TLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILV 122 Query: 151 SLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYT 187 SR +I + +A ++ LNG K G T Sbjct: 123 DQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGAT 159 >5ZWM-4 nrPDB Length = 213 Score = 87.1 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 45/197 (22%), Positives = 93/197 (47%), Gaps = 16/197 (8%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTS-RRFAYIDVTSKEDARYCVE 176 T+++ N P T+ + +L IN V L I+ P + + + +A+I+ ++ DA+Y ++ Sbjct: 10 TVYVGNIDPRITKEQLYELFIQINPV-LRIKYPKDKVLQAYQGYAFIEFYNQGDAQYAIK 68 Query: 177 KLNGL-KIEGYTLVTKVSNPLEKSKRTDSATLEG-----REIMIRNLSTELLDENLLRES 230 +N ++ + + + S + ++ I+NL+ + +D + L + Sbjct: 69 IMNNTVRLYDRLIKVRQVTNSTGTTNLPSNISKDMILPIAKLFIKNLA-DSIDSDQLVKI 127 Query: 231 FEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADK 289 F FG + I P + CA++ FE+ + A+ A++ +N L+ N I+V A K Sbjct: 128 FNKFGKL--IREPEIFYLSNGKLKCAYVYFEDFEKADLAIKSLNNQLVANNRITVDYAFK 185 Query: 290 K----PFLERNEVKRLL 302 + ++V RLL Sbjct: 186 ENGKGNAKYGDDVDRLL 202 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 4/78 (5%) Query: 209 GREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAER 268 G + + N+ + E L E F + +I P + ++ AF+ F N+ A+ Sbjct: 8 GNTVYVGNIDPRITKEQ-LYELFIQINPVLRIKYPKDKVLQAY-QGYAFIEFYNQGDAQY 65 Query: 269 ALQ-MNRSL-LGNREISV 284 A++ MN ++ L +R I V Sbjct: 66 AIKIMNNTVRLYDRLIKV 83 >3SXL-A nrPDB Length = 184 Score = 82.5 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 38/181 (20%), Positives = 79/181 (43%), Gaps = 14/181 (7%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 + L + P T R + L + I + + + S +A++D TS+ D++ Sbjct: 13 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRA 72 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRES-FEG 233 ++ LNG+ + L + P +S ++ + + NL + D+ L ++ F Sbjct: 73 IKVLNGITVRNKRLKVSYARPGGES-------IKDTNLYVTNLPRTITDDQL--DTIFGK 123 Query: 234 FGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGN--REISVSLADKK 290 +GSI + NI K AF+ + ++ A+ A+ +N + + +SV LA++ Sbjct: 124 YGSIVQKNILR-DKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEGGSQPLSVRLAEEH 182 Query: 291 P 291 Sbjct: 183 G 183 Score = 66.3 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 10/155 (6%) Query: 41 TTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVADSLKKNFRF--ARIEFARYDGALAAIT 98 T ++V LP+ ++Y F+ GPI + K + F A ++F + AI Sbjct: 15 TNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSFGYAFVDFTSEMDSQRAIK 74 Query: 99 KTHKVVGQNE-IIVSH-------LTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLP 150 + + +N+ + VS+ + + L++TN P + T + + + L Sbjct: 75 VLNGITVRNKRLKVSYARPGGESIKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILR 134 Query: 151 SLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEG 185 R A++ +E+A+ + LN + EG Sbjct: 135 DKLTGRPRGVAFVRYNKREEAQEAISALNNVIPEG 169 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 36/88 (40%), Gaps = 3/88 (3%) Query: 206 TLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDS 265 +++ L ++ D L F G I I K ++ AF+ F ++ Sbjct: 11 RASNTNLIVNYLPQDMTDRE-LYALFRAIGPINTCRIMRDYKT-GYSFGYAFVDFTSEMD 68 Query: 266 AERALQ-MNRSLLGNREISVSLADKKPF 292 ++RA++ +N + N+ + VS A Sbjct: 69 SQRAIKVLNGITVRNKRLKVSYARPGGE 96 >5EN1-A nrPDB Length = 184 Score = 74.8 bits (182), Expect = 7e-14, Method: Composition-based stats. Identities = 28/176 (15%), Positives = 71/176 (40%), Gaps = 4/176 (2%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++ T+ ++R+ + + + + SR F ++ +S + + Sbjct: 12 LFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAA- 70 Query: 179 NGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIE 238 I+G + K + E+S + A + +++ + + E +E+ LR+ FE +G I+ Sbjct: 71 RPHSIDGRVVEPKRAVAREESGK-PGAHVTVKKLFVGGI-KEDTEEHHLRDYFEEYGKID 128 Query: 239 KINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLLGNREISVSLADKKPFLE 294 I I ++ F+ F++ D ++ + + V A + ++ Sbjct: 129 TIEI-ITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEMQ 183 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 57/174 (32%), Gaps = 15/174 (8%) Query: 39 ELTTVLVKNLPKSYNQNKVYKYFKHCGP----IIHVDVADSLKKNFRFARIE-FARYDGA 93 + + + L + + Y++ G ++ D A + F F A D A Sbjct: 8 QFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAA 67 Query: 94 LAA--------ITKTHKVVGQNEI--IVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVV 143 +AA + + + V + E +H+T L++ + ++RD ++ + Sbjct: 68 MAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKI 127 Query: 144 ALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLE 197 + + R F ++ + V + V K + E Sbjct: 128 DTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQE 181 >2CJK-A nrPDB Length = 167 Score = 73.6 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 28/175 (16%), Positives = 62/175 (35%), Gaps = 11/175 (6%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 C +++ T+ N+R+ V + SR F ++ V Sbjct: 3 SCKMFIGGLNWDTTEDNLREYFGKYGTVTDLKIMKDPATGRSRGFGFLSFEKPSSVDEVV 62 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFG 235 + + L G + K + P D G +I + + ++ E F +G Sbjct: 63 KTQHILD--GKVIDPKRAIP------RDEQDKTG-KIFVGGIGPDV-RPKEFEEFFSQWG 112 Query: 236 SIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLLGNREISVSLADKK 290 +I + K+ + F+ +++ D+ +R Q +R+I + A+ + Sbjct: 113 TIIDAQL-MLDKDTGQSRGFGFVTYDSADAVDRVCQNKFIDFKDRKIEIKRAEPR 166 >4LMZ-A nrPDB Length = 180 Score = 69.4 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 37/178 (20%), Positives = 75/178 (42%), Gaps = 16/178 (8%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN--TSRRFAYIDVTSKEDARYCVE 176 +++ P S++++ +++L + V L N S+ ++ +++ A Sbjct: 11 MFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQN 70 Query: 177 KLNGLKIEGYTLVTKVSNPLEKSKRTD--SATLEGREIMIRNLSTELLDENLLRESFEGF 234 L+ +K + + +P++ S +E R++ I +S + +EN +R F F Sbjct: 71 ALHNIKT-----LPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKC-NENDIRVMFSPF 124 Query: 235 GSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL----QMNRSLLGNREISVSLAD 288 G IE+ I G + CAF+ F + A+ A+ Q + I V AD Sbjct: 125 GQIEECRILRGPD--GLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFAD 180 >5ZWN-V nrPDB Length = 523 Score = 65.9 bits (159), Expect = 4e-11, Method: Composition-based stats. Identities = 35/233 (15%), Positives = 78/233 (33%), Gaps = 66/233 (28%) Query: 115 TECTLWMTNFPPSYTQRNIRDLL-QDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARY 173 C++++ + P+ T+ + +L + + + S+ + ++ T+ ++ + Sbjct: 161 NNCSIFVGDLAPNVTESQLFELFINRYASTSHAKIVHDQVTGMSKGYGFVKFTNSDEQQL 220 Query: 174 CVEKLNGLKIEGYTLVT----------------KVSNPLEKSKRTDSATLE--------- 208 + ++ G+ + G + S+ ++ DS L Sbjct: 221 ALSEMQGVFLNGRAIKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDSRFLSKGQSFLSNG 280 Query: 209 -------------------------------GREIMIRNLSTELLDENLLRESFEGFGSI 237 + I LS L+ E+ LR F+ FG+I Sbjct: 281 NNNMGFKRNHMSQFIYPVQQQPSLNHFTDPNNTTVFIGGLS-SLVTEDELRAYFQPFGTI 339 Query: 238 EKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADK 289 + IP CC F+ + ++ SAE A+ M + N + +S Sbjct: 340 VYVKIP-------VGKCCGFVQYVDRLSAEAAIAGMQGFPIANSRVRLSWGRS 385 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 33/213 (15%), Positives = 77/213 (36%), Gaps = 20/213 (9%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRL-----------PSLRFNTSRRFAYIDVTS 167 L+M + P++ + +R + + +++R+ S+ ++ + ++D S Sbjct: 56 LYMGDLDPTWDKNTVRQIWASLGEANINVRMMWNNTLNNGSRSSMGPKNNQGYCFVDFPS 115 Query: 168 KEDARYCVEKLNGL--KIEGYTLVTKVSNPLEKSKRTDSATLEGRE---IMIRNLSTELL 222 A + K L L + + ++ I + +L+ + Sbjct: 116 STHAANALLKNGMLIPNFPNKKLKLNWATSSYSNSNNSLNNVKSGNNCSIFVGDLAPNVT 175 Query: 223 DENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLGNRE 281 + L + S I Q + F+ F N D + AL +M L R Sbjct: 176 ESQLFELFINRYASTSHAKIVHDQVT-GMSKGYGFVKFTNSDEQQLALSEMQGVFLNGRA 234 Query: 282 ISVS-LADKKPFLER-NEVKRLLASRNSKELET 312 I V + ++ + N+ R +S N++ +++ Sbjct: 235 IKVGPTSGQQQHVSGNNDYNRSSSSLNNENVDS 267 Score = 29.3 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 11/81 (13%), Positives = 31/81 (38%), Gaps = 9/81 (11%) Query: 106 QNEIIVSHLTE---CTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAY 162 Q + ++H T+ T+++ T+ +R Q + + +++P + + Sbjct: 299 QQQPSLNHFTDPNNTTVFIGGLSSLVTEDELRAYFQPFGTI-VYVKIP-----VGKCCGF 352 Query: 163 IDVTSKEDARYCVEKLNGLKI 183 + + A + + G I Sbjct: 353 VQYVDRLSAEAAIAGMQGFPI 373 >3NNA-A nrPDB Length = 175 Score = 64.7 bits (156), Expect = 8e-11, Method: Composition-based stats. Identities = 36/179 (20%), Positives = 75/179 (41%), Gaps = 18/179 (10%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN---TSRRFAYIDVTSKEDARYCV 175 +++ P +++++++R+L + V I + R S+ ++ +++ A Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAV-YEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 176 EKLNGLKI--EGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEG 233 L+ +K+ + + EK+ +E R++ I +S + EN +R F Sbjct: 65 NALHNMKVLPGMHHPIQMKPADSEKNNA-----VEDRKLFIGMISKKCT-ENDIRVMFSS 118 Query: 234 FGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL----QMNRSLLGNREISVSLAD 288 FG IE+ I G + CAF+ F + A+ A+ Q + + V AD Sbjct: 119 FGQIEECRILRGPD--GLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCSSPMVVKFAD 175 >4FXV-A nrPDB Length = 99 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 35/83 (42%) Query: 113 HLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDAR 172 + L + P + TQ +R L I V + + S + +++ + +DA Sbjct: 16 YFQGTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAE 75 Query: 173 YCVEKLNGLKIEGYTLVTKVSNP 195 + LNGL+++ T+ + P Sbjct: 76 RAINTLNGLRLQSKTIKVSYARP 98 Score = 44.7 bits (104), Expect = 7e-05, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 41/96 (42%), Gaps = 3/96 (3%) Query: 193 SNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFN 252 S+ + ++ +G +++ N + + ++ LR F G +E + K + Sbjct: 3 SDKIHHHHHHENLYFQGTNLIV-NYLPQNMTQDELRSLFSSIGEVESAKLIR-DKVAGHS 60 Query: 253 NCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLA 287 F+ + AERA+ +N L ++ I VS A Sbjct: 61 LGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYA 96 >5SZW-A nrPDB Length = 101 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 34/78 (43%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 L + P + TQ +R L I V + + S + +++ + +DA + Sbjct: 23 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 82 Query: 178 LNGLKIEGYTLVTKVSNP 195 LNGL+++ T+ + P Sbjct: 83 LNGLRLQSKTIKVSYARP 100 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 2/97 (2%) Query: 192 VSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSF 251 +SN E D GR +I N + + ++ LR F G +E + K Sbjct: 3 MSNGYEDHMAEDCRGDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIR-DKVAGH 61 Query: 252 NNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLA 287 + F+ + AERA+ +N L ++ I VS A Sbjct: 62 SLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYA 98 >3HI9-A nrPDB Length = 84 Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 34/78 (43%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 L + P + TQ +R L I V + + S + +++ + +DA + Sbjct: 6 NLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINT 65 Query: 178 LNGLKIEGYTLVTKVSNP 195 LNGL+++ T+ + P Sbjct: 66 LNGLRLQSKTIKVSYARP 83 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 209 GREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAER 268 GR +I N + + ++ LR F G +E + K + F+ + AER Sbjct: 3 GRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIR-DKVAGHSLGYGFVNYVTAKDAER 61 Query: 269 ALQ-MNRSLLGNREISVSLA 287 A+ +N L ++ I VS A Sbjct: 62 AINTLNGLRLQSKTIKVSYA 81 >1D8Z-A nrPDB Length = 89 Score = 60.9 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 35/87 (40%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 ++ L + P + TQ + L I + + S + +++ + DA Sbjct: 3 SKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKA 62 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKR 201 + LNGLK++ T+ + P S R Sbjct: 63 INTLNGLKLQTKTIKVSYARPSSASIR 89 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 35/76 (46%), Gaps = 4/76 (5%) Query: 216 NLSTELLDENLLRESF-EGFGSIEKINIPAGQKEH--SFNNCCAFMVFENKDSAERALQ- 271 NL L +N+ ++ F FGSI I ++ + F+ + + + A++A+ Sbjct: 6 NLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINT 65 Query: 272 MNRSLLGNREISVSLA 287 +N L + I VS A Sbjct: 66 LNGLKLQTKTIKVSYA 81 >2DH7-A nrPDB Length = 105 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERA 269 + + +LS E+ E+ ++ +F FG I + + F+ F NK AE A Sbjct: 16 FHVFVGDLSPEITTED-IKSAFAPFGKISDARVVKDM-ATGKSKGYGFVSFYNKLDAENA 73 Query: 270 L-QMNRSLLGNREISVSLADKKP 291 + M LG R+I + A +KP Sbjct: 74 IVHMGGQWLGGRQIRTNWATRKP 96 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 35/87 (40%), Gaps = 3/87 (3%) Query: 105 GQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYID 164 GQ + +H +++ + P T +I+ ++ + + + S+ + ++ Sbjct: 7 GQKKDTSNHFH---VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVS 63 Query: 165 VTSKEDARYCVEKLNGLKIEGYTLVTK 191 +K DA + + G + G + T Sbjct: 64 FYNKLDAENAIVHMGGQWLGGRQIRTN 90 >2MYF-A nrPDB Length = 89 Score = 55.9 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 34/77 (44%), Gaps = 3/77 (3%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL- 270 + + + E +DE L + F FG I I +P N AF+ + D A+ AL Sbjct: 13 LFVGGID-ETIDEKSLYDIFSSFGDIRNIEVPLNMTTK-KNRGFAFVEYVEVDDAKHALY 70 Query: 271 QMNRSLLGNREISVSLA 287 MN L + I V+ + Sbjct: 71 NMNNFELNGKRIHVNYS 87 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 38/86 (44%), Gaps = 4/86 (4%) Query: 112 SHLTECT----LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTS 167 SH+++ L++ + ++++ D+ + ++ +R FA+++ Sbjct: 2 SHMSDNNATDILFVGGIDETIDEKSLYDIFSSFGDIRNIEVPLNMTTKKNRGFAFVEYVE 61 Query: 168 KEDARYCVEKLNGLKIEGYTLVTKVS 193 +DA++ + +N ++ G + S Sbjct: 62 VDDAKHALYNMNNFELNGKRIHVNYS 87 >2SXL-A nrPDB Length = 88 Score = 54.7 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 35/81 (43%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 + L + P T R + L + I + + + S +A++D TS+ D++ Sbjct: 2 SNTNLIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKTGYSYGYAFVDFTSEMDSQRA 61 Query: 175 VEKLNGLKIEGYTLVTKVSNP 195 ++ LNG+ + L + P Sbjct: 62 IKVLNGITVRNKRLKVSYARP 82 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Query: 213 MIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ- 271 +I N + + + L F G I I K ++ AF+ F ++ ++RA++ Sbjct: 6 LIVNYLPQDMTDRELYALFRAIGPINTCRIMRDYKT-GYSYGYAFVDFTSEMDSQRAIKV 64 Query: 272 MNRSLLGNREISVSLADKKPF 292 +N + N+ + VS A Sbjct: 65 LNGITVRNKRLKVSYARPGGE 85 >1P1T-A nrPDB Length = 104 Score = 54.7 bits (130), Expect = 7e-08, Method: Composition-based stats. Identities = 12/73 (16%), Positives = 30/73 (41%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 ++++ N P T+ ++D+ ++ V + + + + + +E A + Sbjct: 10 SVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRN 69 Query: 178 LNGLKIEGYTLVT 190 LNG + G L Sbjct: 70 LNGREFSGRALRV 82 >5EV3-A nrPDB Length = 201 Score = 53.6 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 33/188 (17%), Positives = 75/188 (39%), Gaps = 22/188 (11%) Query: 119 LWMTNFPPSYTQRNIRDLLQD---INVVALSIRLPSLR--FNTSRRFAYIDVTSKEDARY 173 L++ N P T+ + D + + + P L N + FA+++ S ++ Sbjct: 11 LYVGNIPFGITEEAMMDFFNAQMRLGGLTQAPGNPVLAVQINQDKNFAFLEFRSVDETTQ 70 Query: 174 CVEKLNGLKIEGYTLVTKVS---NPLEKSKRTDSATLEG----------REIMIRNLSTE 220 + +G+ +G +L + PL S + G ++ I L Sbjct: 71 AMA-FDGIIFQGQSLKIRRPHDYQPLPGMSENPSVYVPGVVSTVVPDSAHKLFIGGL-PN 128 Query: 221 LLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGN 279 L+++ ++E FG ++ N+ + AF + + + ++A+ +N LG+ Sbjct: 129 YLNDDQVKELLTSFGPLKAFNLVKDS-ATGLSKGYAFCEYVDINVTDQAIAGLNGMQLGD 187 Query: 280 REISVSLA 287 +++ V A Sbjct: 188 KKLLVQRA 195 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 11/85 (12%), Positives = 32/85 (37%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 + L++ P +++LL + + S+ +A+ + Sbjct: 117 SAHKLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDINVTDQA 176 Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKS 199 + LNG+++ L+ + ++ K+ Sbjct: 177 IAGLNGMQLGDKKLLVQRASVGAKN 201 >1SXL-A nrPDB Length = 97 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%) Query: 114 LTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARY 173 + + L++TN P + T + + + L R A++ +E+A+ Sbjct: 11 IKDTNLYVTNLPRTITDDQLDTIFGKYGSIVQKNILRDKLTGRPRGVAFVRYNKREEAQE 70 Query: 174 CVEKLNGLKIEG 185 + LN + EG Sbjct: 71 AISALNNVIPEG 82 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 42/89 (47%), Gaps = 7/89 (7%) Query: 207 LEGREIMIRNLSTELLDENLLRES-FEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDS 265 ++ + + NL + D+ L ++ F +GSI + NI K AF+ + ++ Sbjct: 11 IKDTNLYVTNLPRTITDDQL--DTIFGKYGSIVQKNILR-DKLTGRPRGVAFVRYNKREE 67 Query: 266 AERALQ-MNRSLLGN--REISVSLADKKP 291 A+ A+ +N + + +SV LA++ Sbjct: 68 AQEAISALNNVIPEGGSQPLSVRLAEEHG 96 >5MQF-o nrPDB Length = 301 Score = 52.8 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 30/90 (33%), Positives = 43/90 (47%), Gaps = 5/90 (5%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 + + L+ E+ D+ +L +F FG I I IP E + AF+ FE + A A+ Sbjct: 8 LYVGGLAEEV-DDKVLHAAFIPFGDITDIQIP-LDYETEKHRGFAFVEFELAEDAAAAID 65 Query: 272 -MNRSLLGNREISVSLADKKPFLERNEVKR 300 MN S L R I V+LA KP + R Sbjct: 66 NMNESELFGRTIRVNLA--KPMRIKEGSSR 93 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 34/83 (40%), Gaps = 2/83 (2%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 173 T+ L++ + + + I++P R FA+++ EDA Sbjct: 4 TKRVLYVGGLAEEVDDKVLHAAFIPFGDIT-DIQIPLDYETEKHRGFAFVEFELAEDAAA 62 Query: 174 CVEKLNGLKIEGYTLVTKVSNPL 196 ++ +N ++ G T+ ++ P+ Sbjct: 63 AIDNMNESELFGRTIRVNLAKPM 85 >1X5O-A nrPDB Length = 114 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 L+++N P S ++ + ++L+ V +S R+ TSR + + S E + Sbjct: 27 NLYISNLPLSMDEQELENMLKPFGQV-ISTRILRDSSGTSRGVGFARMESTEKCEAVIGH 85 Query: 178 LNGLKIEGYTLVTKVSNPL 196 NG I+ V+ + PL Sbjct: 86 FNGKFIKTPPGVSAPTEPL 104 Score = 35.9 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 26/84 (30%), Gaps = 4/84 (4%) Query: 199 SKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFM 258 ++ + + I NL +DE L + FG + I + + F Sbjct: 15 AQMAKQQEQDPTNLYISNL-PLSMDEQELENMLKPFGQVISTRI--LRDSSGTSRGVGFA 71 Query: 259 VFENKDSAERAL-QMNRSLLGNRE 281 E+ + E + N + Sbjct: 72 RMESTEKCEAVIGHFNGKFIKTPP 95 >4ZKA-A nrPDB Length = 100 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L ++N P + ++R + + + + R S+ F ++ + DA EKL Sbjct: 11 LHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNER--GSKGFGFVTFENSADADRAREKL 68 Query: 179 NGLKIEGYTL-VTKVSNPLEKSKRTDSATLEG 209 +G +EG + V + + +K+T + G Sbjct: 69 HGTVVEGRKIEVNNATARVMTNKKTVNPYTNG 100 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Query: 227 LRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVS 285 LR+ F FG I + I ++ + F+ FEN A+RA + ++ +++ R+I V+ Sbjct: 25 LRQMFGQFGKILDVEIIFNERG---SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVN 81 Query: 286 LADKKPFLERNEV 298 A + + V Sbjct: 82 NATARVMTNKKTV 94 >3MDF-A nrPDB Length = 85 Score = 52.0 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 3/85 (3%) Query: 204 SATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENK 263 S R + + L+ E+ D+ +L +F FG I I IP E + AF+ FE Sbjct: 2 SMATTKRVLYVGGLAEEV-DDKVLHAAFIPFGDITDIQIP-LDYETEKHRGFAFVEFELA 59 Query: 264 DSAERALQ-MNRSLLGNREISVSLA 287 + A A+ MN S L R I V+LA Sbjct: 60 EDAAAAIDNMNESELFGRTIRVNLA 84 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 173 T+ L++ + + + I++P R FA+++ EDA Sbjct: 6 TKRVLYVGGLAEEVDDKVLHAAFIPFGDIT-DIQIPLDYETEKHRGFAFVEFELAEDAAA 64 Query: 174 CVEKLNGLKIEGYTLVTKVS 193 ++ +N ++ G T+ ++ Sbjct: 65 AIDNMNESELFGRTIRVNLA 84 >2KU7-A nrPDB Length = 140 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 + + L+ E+ D+ +L +F FG I I IP E + AF+ FE + A A+ Sbjct: 66 LYVGGLAEEV-DDKVLHAAFIPFGDITDIQIP-LDYETEKHRGFAFVEFELAEDAAAAID 123 Query: 272 -MNRSLLGNREISVSLA 287 MN S L R I V+LA Sbjct: 124 NMNESELFGRTIRVNLA 140 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 173 T+ L++ + + + I++P R FA+++ EDA Sbjct: 62 TKRVLYVGGLAEEVDDKVLHAAFIPFGDIT-DIQIPLDYETEKHRGFAFVEFELAEDAAA 120 Query: 174 CVEKLNGLKIEGYTLVTKVS 193 ++ +N ++ G T+ ++ Sbjct: 121 AIDNMNESELFGRTIRVNLA 140 >2CQB-A nrPDB Length = 102 Score = 52.0 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 27/77 (35%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 + + L+ E+ D+ +L +F FG I I IP E + AF+ FE + A A+ Sbjct: 15 LYVGGLAEEV-DDKVLHAAFIPFGDITDIQIP-LDYETEKHRGFAFVEFELAEDAAAAID 72 Query: 272 -MNRSLLGNREISVSLA 287 MN S L R I V+LA Sbjct: 73 NMNESELFGRTIRVNLA 89 Score = 51.3 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 36/91 (39%), Gaps = 2/91 (2%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN-TSRRFAYIDVTSKEDARY 173 T+ L++ + + + I++P R FA+++ EDA Sbjct: 11 TKRVLYVGGLAEEVDDKVLHAAFIPFGDIT-DIQIPLDYETEKHRGFAFVEFELAEDAAA 69 Query: 174 CVEKLNGLKIEGYTLVTKVSNPLEKSKRTDS 204 ++ +N ++ G T+ ++ P+ + S Sbjct: 70 AIDNMNESELFGRTIRVNLAKPMRIKESGPS 100 >2DH9-A nrPDB Length = 89 Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 5/77 (6%) Query: 209 GREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAER 268 I +RNL + +L++ F G + +I E+ + C + FE+ + AER Sbjct: 5 SSGIFVRNLPFDFT-WKMLKDKFNECGHVLYADIKM---ENGKSKGCGVVKFESPEVAER 60 Query: 269 ALQ-MNRSLLGNREISV 284 A + MN L REI V Sbjct: 61 ACRMMNGMKLSGREIDV 77 >2DGS-A nrPDB Length = 99 Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 31/86 (36%), Gaps = 1/86 (1%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 +++ P + + +R+ + VV + + R F +I ++ V + Sbjct: 13 IFVGGIPHNCGETELREYFKKFGVVTEVVMIYDAEKQRPRGFGFITFEDEQSVDQAVN-M 71 Query: 179 NGLKIEGYTLVTKVSNPLEKSKRTDS 204 + I G + K + P + S Sbjct: 72 HFHDIMGKKVEVKRAEPRDSKSSGPS 97 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 211 EIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL 270 +I + + E LRE F+ FG + ++ + E F+ FE++ S ++A+ Sbjct: 12 KIFVGGI-PHNCGETELREYFKKFGVVTEV-VMIYDAEKQRPRGFGFITFEDEQSVDQAV 69 Query: 271 QMNRSLLGNREISVSLADKK 290 M+ + +++ V A+ + Sbjct: 70 NMHFHDIMGKKVEVKRAEPR 89 >2YWK-A nrPDB Length = 95 Score = 51.3 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 28/71 (39%), Gaps = 1/71 (1%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 T+++ N + + +L + + + R + F ++ E Y + Sbjct: 18 TVFVGNLEARVREEILYELFLQAGPLT-KVTICKDREGKPKSFGFVCFKHPESVSYAIAL 76 Query: 178 LNGLKIEGYTL 188 LNG+++ G + Sbjct: 77 LNGIRLYGRPI 87 >2CQ3-A nrPDB Length = 103 Score = 50.5 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L ++N P + ++R + + + + R S+ F ++ + DA EKL Sbjct: 18 LHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNER--GSKGFGFVTFENSADADRAREKL 75 Query: 179 NGLKIEGYTL-VTKVSNPLEKS 199 +G +EG + V + + + Sbjct: 76 HGTVVEGRKIEVNNATARVMTN 97 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Query: 227 LRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVS 285 LR+ F FG I + I ++ + F+ FEN A+RA + ++ +++ R+I V+ Sbjct: 32 LRQMFGQFGKILDVEIIFNERG---SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVN 88 Query: 286 LADKK 290 A + Sbjct: 89 NATAR 93 >1D9A-A nrPDB Length = 85 Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 15/70 (21%), Positives = 29/70 (41%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 + L+++ P + +Q+ + L + S L SR +I + +A + Sbjct: 1 DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAI 60 Query: 176 EKLNGLKIEG 185 + LNG K G Sbjct: 61 KGLNGQKPLG 70 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 33/83 (39%), Gaps = 5/83 (6%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERA 269 + + L + + + + + F +G I I + + F+ F+ + AE A Sbjct: 2 ANLYVSGL-PKTMSQKEMEQLFSQYGRIITSRI-LLDQATGVSRGVGFIRFDKRIEAEEA 59 Query: 270 LQ-MNRS--LLGNREISVSLADK 289 ++ +N L I+V A+ Sbjct: 60 IKGLNGQKPLGAAEPITVKFANN 82 >6D0Y-A nrPDB Length = 176 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 42/109 (38%), Gaps = 10/109 (9%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 CTL++ N T+ I +L + I T+ F +++ S+ DA + Sbjct: 59 SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAM 118 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDE 224 +NG +++ + + D+ EGR+ ++ DE Sbjct: 119 RYINGTRLDDRII------RTDW----DAGFKEGRQYGRGRSGGQVRDE 157 >5OO6-B nrPDB Length = 158 Score = 49.0 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 42/109 (38%), Gaps = 10/109 (9%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 CTL++ N T+ I +L + I T+ F +++ S+ DA + Sbjct: 41 SCTLYVGNLSFYTTEEQIYELFSKSGDIKKIIMGLDKMKKTACGFCFVEYYSRADAENAM 100 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDE 224 +NG +++ + + D+ EGR+ ++ DE Sbjct: 101 RYINGTRLDDRII------RTDW----DAGFKEGRQYGRGRSGGQVRDE 139 >5ZWM-X nrPDB Length = 148 Score = 48.6 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 29/78 (37%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 +++ N T+ +I + + V I S+ FAY+ + V Sbjct: 30 NAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAV 89 Query: 176 EKLNGLKIEGYTLVTKVS 193 + LNG KI G L + Sbjct: 90 DNLNGFKIGGRALKIDHT 107 Score = 43.9 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 64/145 (44%), Gaps = 21/145 (14%) Query: 175 VEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGF 234 ++++N +++ + + +P + + I I NL+ EL + ++L F + Sbjct: 4 IQQINDKELQ-----SGILSPHQSWHNE---YKDNAYIYIGNLNRELTEGDIL-TVFSEY 54 Query: 235 GSIEKINIPAGQKEH-SFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKKPF 292 G +++ + E+ + A++ +E++ S A+ +N +G R + + +P Sbjct: 55 GV--PVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPK 112 Query: 293 LE--------RNEVKRLLASRNSKE 309 + E+ R + S+N+ E Sbjct: 113 RSLQKYYEAVKEELDRDIVSKNNAE 137 >2ERR-A nrPDB Length = 109 Score = 48.6 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 34/80 (42%), Gaps = 3/80 (3%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L ++N P + ++R + + + + R S+ F ++ + DA EKL Sbjct: 32 LHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNER--GSKGFGFVTFENSADADRAREKL 89 Query: 179 NGLKIEGYTL-VTKVSNPLE 197 +G +EG + V + + Sbjct: 90 HGTVVEGRKIEVNNATARVM 109 Score = 43.2 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Query: 227 LRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVS 285 LR+ F FG I + I ++ + F+ FEN A+RA + ++ +++ R+I V+ Sbjct: 46 LRQMFGQFGKILDVEIIFNERG---SKGFGFVTFENSADADRAREKLHGTVVEGRKIEVN 102 Query: 286 LADKK 290 A + Sbjct: 103 NATAR 107 >1H6K-X nrPDB Length = 98 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 34/75 (45%), Gaps = 1/75 (1%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 CTL++ N T+ I +L + I + + T+ F +++ S+ DA + Sbjct: 18 SCTLYVGNLSFYTTEEQIYELFSKSGDIK-KIIMGLDKMKTACGFCFVEYYSRADAENAM 76 Query: 176 EKLNGLKIEGYTLVT 190 +NG +++ + T Sbjct: 77 RYINGTRLDDRIIRT 91 >2MGZ-B nrPDB Length = 105 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Query: 211 EIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL 270 +I + L + L E FE FG IE+ + + + F+ +++ SAERA Sbjct: 18 KIFVGGL-PYHTSDKTLHEYFEQFGDIEEA-VVITDRNTQKSRGYGFVTMKDRASAERAC 75 Query: 271 QMNRSLLGNREISVSLA 287 + ++ R+ +V+LA Sbjct: 76 KDPNPIIDGRKANVNLA 92 Score = 45.9 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 11/96 (11%), Positives = 36/96 (37%), Gaps = 6/96 (6%) Query: 98 TKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTS 157 T VVG + + + +++ P + + + + + + ++ + S Sbjct: 3 TNAEPVVGSRDTMFT-----KIFVGGLPYHTSDKTLHEYFEQFGDIEEAVVITDRNTQKS 57 Query: 158 RRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVS 193 R + ++ + + A + N + I+G ++ Sbjct: 58 RGYGFVTMKDRASAERACKDPNPI-IDGRKANVNLA 92 >2HYI-B nrPDB Length = 91 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 39/90 (43%), Gaps = 3/90 (3%) Query: 203 DSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN 262 ++EG + + + E +E+ + + F +G I+ I++ + + + +E Sbjct: 3 PQRSVEGWILFVTGVHEEATEED-IHDKFAEYGEIKNIHL-NLDRRTGYLKGYTLVEYET 60 Query: 263 KDSAERALQ-MNRSLLGNREISVSLADKKP 291 A+ A++ +N L + ISV + Sbjct: 61 YKEAQAAMEGLNGQDLMGQPISVDWCFVRG 90 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 29/70 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T T+ +I D + + R + + ++ + ++A+ +E L Sbjct: 12 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 71 Query: 179 NGLKIEGYTL 188 NG + G + Sbjct: 72 NGQDLMGQPI 81 >1P27-B nrPDB Length = 106 Score = 46.6 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 39/90 (43%), Gaps = 3/90 (3%) Query: 203 DSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN 262 ++EG + + + E +E+ + + F +G I+ I++ + + + +E Sbjct: 17 PQRSVEGWILFVTGVHEEATEED-IHDKFAEYGEIKNIHL-NLDRRTGYLKGYTLVEYET 74 Query: 263 KDSAERALQ-MNRSLLGNREISVSLADKKP 291 A+ A++ +N L + ISV + Sbjct: 75 YKEAQAAMEGLNGQDLMGQPISVDWCFVRG 104 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 29/70 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T T+ +I D + + R + + ++ + ++A+ +E L Sbjct: 26 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 85 Query: 179 NGLKIEGYTL 188 NG + G + Sbjct: 86 NGQDLMGQPI 95 >5YZG-w nrPDB Length = 174 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 203 DSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN 262 ++EG + + + E +E+ + + F +G I+ I++ + + + +E Sbjct: 66 PQRSVEGWILFVTGVHEEATEED-IHDKFAEYGEIKNIHL-NLDRRTGYLKGYTLVEYET 123 Query: 263 KDSAERALQ-MNRSLLGNREISV 284 A+ A++ +N L + ISV Sbjct: 124 YKEAQAAMEGLNGQDLMGQPISV 146 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 29/70 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T T+ +I D + + R + + ++ + ++A+ +E L Sbjct: 75 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 134 Query: 179 NGLKIEGYTL 188 NG + G + Sbjct: 135 NGQDLMGQPI 144 >3EX7-B nrPDB Length = 126 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 203 DSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN 262 ++EG + + + E +E+ + + F +G I+ I++ + + + +E Sbjct: 16 PQRSVEGWILFVTGVHEEATEED-IHDKFAEYGEIKNIHL-NLDRRTGYLKGYTLVEYET 73 Query: 263 KDSAERALQ-MNRSLLGNREISV 284 A+ A++ +N L + ISV Sbjct: 74 YKEAQAAMEGLNGQDLMGQPISV 96 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 29/70 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T T+ +I D + + R + + ++ + ++A+ +E L Sbjct: 25 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 84 Query: 179 NGLKIEGYTL 188 NG + G + Sbjct: 85 NGQDLMGQPI 94 >2J0Q-D nrPDB Length = 109 Score = 46.3 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 203 DSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN 262 ++EG + + + E +E+ + + F +G I+ I++ + + + +E Sbjct: 1 PQRSVEGWILFVTGVHEEATEED-IHDKFAEYGEIKNIHL-NLDRRTGYLKGYTLVEYET 58 Query: 263 KDSAERALQ-MNRSLLGNREISV 284 A+ A++ +N L + ISV Sbjct: 59 YKEAQAAMEGLNGQDLMGQPISV 81 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 29/70 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T T+ +I D + + R + + ++ + ++A+ +E L Sbjct: 10 LFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGL 69 Query: 179 NGLKIEGYTL 188 NG + G + Sbjct: 70 NGQDLMGQPI 79 >6QX9-R nrPDB Length = 480 Score = 45.1 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 3/82 (3%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN-KDSAER 268 I +L E+ D+ L R +F F S K + K F+ F++ D Sbjct: 381 FRIFCGDLGNEVNDDILAR-AFSRFPSFLKAKVIR-DKRTGKTKGYGFVSFKDPSDYVRA 438 Query: 269 ALQMNRSLLGNREISVSLADKK 290 +MN +G+R I + + K Sbjct: 439 MREMNGKYVGSRPIKLRKSMWK 460 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 7/88 (7%), Positives = 26/88 (29%), Gaps = 2/88 (2%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 ++ + + + + R ++ + ++ D + ++ Sbjct: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 Query: 179 NGLKIEGYTLVTKVSNPLEKSKRTDSAT 206 NG + + + S + K + D Sbjct: 443 NGKYVGSRPIKLRKS--MWKDRNLDVVR 468 >6FEC-u nrPDB Length = 636 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 51/126 (40%), Gaps = 9/126 (7%) Query: 179 NGLKIEGYTLVTKVSNPLE----KSKRTDSATLEG---REIMIRNLSTELLDENLLRESF 231 N + + + P + D + L + NL ++ +E+ ++E F Sbjct: 83 NDDDVYRAPPIDRSILPTAPRAAREPNIDRSRLPKSPPYTAFLGNLPYDVTEES-IKEFF 141 Query: 232 EGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLLGNREISVSLADKKP 291 G +I + +P + FE+ DS AL +N LGNR I V +AD+ Sbjct: 142 RGL-NISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEESLGNRRIRVDVADQAQ 200 Query: 292 FLERNE 297 +R++ Sbjct: 201 DKDRDD 206 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 38/96 (39%), Gaps = 5/96 (5%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSR--RFAYIDVTSKEDARYCV 175 T ++ N P T+ +I++ + +N+ ++RLP N R F Y + + Sbjct: 122 TAFLGNLPYDVTEESIKEFFRGLNI--SAVRLPREPSNPERLKGFGYAEFEDLDSLLSA- 178 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEGRE 211 LN + + V++ + R D + R Sbjct: 179 LSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRN 214 >6QX9-1K nrPDB Length = 437 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 31/75 (41%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 TL++ T+ +R + + + S R R +A+I+ + D + Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 178 LNGLKIEGYTLVTKV 192 +G KI+G ++ V Sbjct: 164 ADGKKIDGRRVLVDV 178 >3CW1-K nrPDB Length = 216 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 31/75 (41%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 TL++ T+ +R + + + S R R +A+I+ + D + Sbjct: 104 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 163 Query: 178 LNGLKIEGYTLVTKV 192 +G KI+G ++ V Sbjct: 164 ADGKKIDGRRVLVDV 178 >2LEC-A nrPDB Length = 135 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 31/76 (40%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 +L + N + +R + + V SR FA++ K DA ++ Sbjct: 49 SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDA 108 Query: 178 LNGLKIEGYTLVTKVS 193 ++G ++G L +++ Sbjct: 109 MDGAVLDGRELRVQMA 124 >2KN4-A nrPDB Length = 158 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 31/76 (40%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 +L + N + +R + + V SR FA++ K DA ++ Sbjct: 72 SLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDA 131 Query: 178 LNGLKIEGYTLVTKVS 193 ++G ++G L +++ Sbjct: 132 MDGAVLDGRELRVQMA 147 >4PKD-B nrPDB Length = 279 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 31/75 (41%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 TL++ T+ +R + + + S R R +A+I+ + D + Sbjct: 168 TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKH 227 Query: 178 LNGLKIEGYTLVTKV 192 +G KI+G ++ V Sbjct: 228 ADGKKIDGRRVLVDV 242 Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 8/87 (9%) Query: 205 ATLEGREIMIRNLSTELLDENL---LRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFE 261 T I I NL+ ++ + L L F FG I I + K AF++F+ Sbjct: 4 ETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQ----AFVIFK 59 Query: 262 NKDSAERALQ-MNRSLLGNREISVSLA 287 SA AL+ M ++ + + A Sbjct: 60 EVSSATNALRSMQGFPFYDKPMRIQYA 86 >6GML-X nrPDB Length = 404 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 49/86 (56%), Gaps = 11/86 (12%) Query: 226 LLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLGNREISV 284 LLR +F FG+I +++ CAF+ +E +SA++A+ ++N + + + ++ V Sbjct: 299 LLRGAFSPFGNIIDLSM-------DPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKV 351 Query: 285 SLADKKPFLERNEVKRL---LASRNS 307 ++A K+P L+ K + LA +NS Sbjct: 352 NIARKQPMLDAATGKSVWGSLAVQNS 377 Score = 31.2 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 12/78 (15%) Query: 118 TLWM--TNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL++ + P+ +R + L + R A++ E A V Sbjct: 287 TLYVYGEDMTPTL----LRGAFSPFGNI------IDLSMDPPRNCAFVTYEKMESADQAV 336 Query: 176 EKLNGLKIEGYTLVTKVS 193 +LNG ++E L ++ Sbjct: 337 AELNGTQVESVQLKVNIA 354 >2RS2-A nrPDB Length = 109 Score = 42.8 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 14/86 (16%), Positives = 34/86 (39%), Gaps = 3/86 (3%) Query: 112 SHL--TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKE 169 SH+ + C +++ TQ +R+ V + + SR F ++ + Sbjct: 19 SHMGSSGCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQA 78 Query: 170 DARYCVEKLNGLKIEGYTLVTKVSNP 195 + + + +++ T+ KV+ P Sbjct: 79 GVDKVLAQ-SRHELDSKTIDPKVAFP 103 >1OO0-B nrPDB Length = 110 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 30/72 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T+ + I++ D + R S+ +A ++ + + A E L Sbjct: 29 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 88 Query: 179 NGLKIEGYTLVT 190 NG +I G T+ Sbjct: 89 NGAEIMGQTIQV 100 >1RK8-A nrPDB Length = 165 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 30/72 (41%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++T+ + I++ D + R S+ +A ++ + + A E L Sbjct: 75 LFVTSIHEEAQEDEIQEKFCDYGEIKNIHLNLDRRTGFSKGYALVEYETHKQALAAKEAL 134 Query: 179 NGLKIEGYTLVT 190 NG +I G T+ Sbjct: 135 NGAEIMGQTIQV 146 >5X3Y-A nrPDB Length = 96 Score = 41.6 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 38/98 (38%), Gaps = 3/98 (3%) Query: 112 SHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDA 171 SH+ + +++ + T +++ + V ++ + N R F ++ S++ Sbjct: 2 SHMKK--IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIV 59 Query: 172 RYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEG 209 E ++ +I + K + P E T SA Sbjct: 60 EKVCE-IHFHEINNKMVECKKAQPKEVMSPTGSARGRS 96 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 40/91 (43%), Gaps = 2/91 (2%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERA 269 ++I + LS E+ ++ FE FG ++ + K + + F+ FE++D E+ Sbjct: 5 KKIFVGGLSVNTTVED-VKHYFEQFGKVDDAML-MFDKTTNRHRGFGFVTFESEDIVEKV 62 Query: 270 LQMNRSLLGNREISVSLADKKPFLERNEVKR 300 +++ + N+ + A K + R Sbjct: 63 CEIHFHEINNKMVECKKAQPKEVMSPTGSAR 93 >1X4A-A nrPDB Length = 109 Score = 41.2 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 32/76 (42%), Gaps = 3/76 (3%) Query: 115 TECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYC 174 +C +++ N PP ++I D+ + I L + R FA+++ DA Sbjct: 21 NDCRIYVGNLPPDIRTKDIEDVFYKYGAIR-DIDLKNRRGGPP--FAFVEFEDPRDAEDA 77 Query: 175 VEKLNGLKIEGYTLVT 190 V +G +GY L Sbjct: 78 VYGRDGYDYDGYRLRV 93 >6GD1-A nrPDB Length = 206 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 27/72 (37%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 +++ N + + + V + N + F ++ +T+ E+A + L Sbjct: 126 IFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASL 185 Query: 179 NGLKIEGYTLVT 190 NG ++ L Sbjct: 186 NGYRLGDKILQV 197 >6EM1-o nrPDB Length = 220 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 35/87 (40%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 ++++ P + ++ + + + + SR + +++ +KEDA Sbjct: 90 SGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFLEFVNKEDAMIAQ 149 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRT 202 E +N + G+ L +V K ++ Sbjct: 150 ESMNNYLLMGHLLQVRVLPKGAKIEKL 176 >2LXI-A nrPDB Length = 91 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 2/74 (2%) Query: 124 FPPSYTQRNIRDLLQDINVVALSIRLPS-LRFNTSRRFAYIDVTSKEDARYCVE-KLNGL 181 P + T+ +IR LQ V A +RL SR FA+++ + +DA +E + L Sbjct: 9 LPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSL 68 Query: 182 KIEGYTLVTKVSNP 195 I G + S+P Sbjct: 69 NILGQKVSMHYSDP 82 >2DH8-A nrPDB Length = 105 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 17/49 (34%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTS 167 L++ S TQ +R V + + N SR F ++ Sbjct: 19 LFVGGLDWSTTQETLRSYFSQYGEVVDCVIMKDKTTNQSRGFGFVKFKD 67 >2DGP-A nrPDB Length = 106 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 6/82 (7%) Query: 211 EIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDS---AE 267 ++ I + LDE L+ FE FG I ++ + + + CAF+ + ++S A+ Sbjct: 15 KLFIGQI-PRNLDEKDLKPLFEEFGKIYELTVLK-DRFTGMHKGCAFLTYCERESALKAQ 72 Query: 268 RALQMNRSLLG-NREISVSLAD 288 AL ++L G NR I V AD Sbjct: 73 SALHEQKTLPGMNRPIQVKPAD 94 >4WKR-A nrPDB Length = 208 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 24/64 (37%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 E T+++ P + I + V + FA+++ +KE A + Sbjct: 124 ERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAI 183 Query: 176 EKLN 179 E LN Sbjct: 184 EFLN 187 Score = 33.2 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 36/83 (43%), Gaps = 8/83 (9%) Query: 217 LSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSL 276 L + ++ + + F G++ I+IP K AF+ FE K+ A +A++ Sbjct: 131 LLPKNVNHSWIERVFGKCGNVVYISIPH-YKSTGDPKGFAFVEFETKEQAAKAIE----F 185 Query: 277 LGNREISVSLADKKPFLERNEVK 299 L N A +KP + VK Sbjct: 186 LNNPP---EEAPRKPGIFPKTVK 205 Score = 31.2 bits (69), Expect = 0.91, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 36 RNRELTTVLVKNLPKSYNQNKVYKYFKHCGPIIHVDVA--DSLKKNFRFARIEFARYDGA 93 ++ + TV V+ LPK+ N + + + F CG ++++ + S FA +EF + A Sbjct: 120 KDEDERTVYVELLPKNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQA 179 Query: 94 LAAI 97 AI Sbjct: 180 AKAI 183 >1UAW-A nrPDB Length = 77 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 8/61 (13%), Positives = 20/61 (32%) Query: 117 CTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVE 176 C +++ TQ +R+ V + + SR F ++ + + Sbjct: 1 CKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLA 60 Query: 177 K 177 + Sbjct: 61 Q 61 >2BZ2-A nrPDB Length = 121 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 43/75 (57%), Gaps = 8/75 (10%) Query: 226 LLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLGNREISV 284 LLR +F FG+I +++ CAF+ +E +SA++A+ ++N + + + ++ V Sbjct: 53 LLRGAFSPFGNIIDLSM-------DPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKV 105 Query: 285 SLADKKPFLERNEVK 299 ++A K+P L+ K Sbjct: 106 NIARKQPMLDAATGK 120 Score = 31.2 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 12/78 (15%) Query: 118 TLWM--TNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL++ + P+ +R + L + R A++ E A V Sbjct: 41 TLYVYGEDMTPTL----LRGAFSPFGNI------IDLSMDPPRNCAFVTYEKMESADQAV 90 Query: 176 EKLNGLKIEGYTLVTKVS 193 +LNG ++E L ++ Sbjct: 91 AELNGTQVESVQLKVNIA 108 >2MST-A nrPDB Length = 75 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 7/59 (11%), Positives = 22/59 (37%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 +++ + T +++ + V ++ + N R F ++ S++ E Sbjct: 2 IFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEI 60 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 211 EIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL 270 +I + LS E+ ++ FE FG ++ + K + + F+ FE++D E+ Sbjct: 1 KIFVGGLSVNTTVED-VKHYFEQFGKVDDAML-MFDKTTNRHRGFGFVTFESEDIVEKVC 58 Query: 271 QMNRSLLGNREISVSLA 287 +++ + N+ + A Sbjct: 59 EIHFHEINNKMVECKKA 75 >2XS5-A nrPDB Length = 87 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 T+++ + IR V +++ + R S+ + ++ + D + VE Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVK-EVKIITDRTGVSKGYGFVSFYNDVDVQKIVE- 68 Query: 178 LNGLKIEGYTLVTK 191 + + G L Sbjct: 69 -SQINFHGKKLKLG 81 Score = 35.9 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 10/60 (16%), Positives = 26/60 (43%), Gaps = 3/60 (5%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 + + + + DE +R F +GS++++ I + F+ F N ++ ++ Sbjct: 12 VFVGGIDVRM-DETEIRSFFARYGSVKEVKI--ITDRTGVSKGYGFVSFYNDVDVQKIVE 68 >2XS2-A nrPDB Length = 102 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 11/74 (14%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 T+++ + IR V +++ + R S+ + ++ + D + VE Sbjct: 11 TVFVGGIDVRMDETEIRSFFARYGSVK-EVKIITDRTGVSKGYGFVSFYNDVDVQKIVE- 68 Query: 178 LNGLKIEGYTLVTK 191 + + G L Sbjct: 69 -SQINFHGKKLKLG 81 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 38/88 (43%), Gaps = 4/88 (4%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 + + + + DE +R F +GS++++ I + F+ F N ++ ++ Sbjct: 12 VFVGGIDVRM-DETEIRSFFARYGSVKEVKI--ITDRTGVSKGYGFVSFYNDVDVQKIVE 68 Query: 272 MNRSLLGNREISVSLADKKPFLERNEVK 299 ++ +++ + A +K L V+ Sbjct: 69 -SQINFHGKKLKLGPAIRKQNLSTYHVQ 95 >1X5P-A nrPDB Length = 97 Score = 39.7 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 20/70 (28%), Positives = 42/70 (60%), Gaps = 8/70 (11%) Query: 226 LLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL-QMNRSLLGNREISV 284 LLR +F FG+I +++ CAF+ +E +SA++A+ ++N + + + ++ V Sbjct: 29 LLRGAFSPFGNIIDLSM-------DPPRNCAFVTYEKMESADQAVAELNGTQVESVQLKV 81 Query: 285 SLADKKPFLE 294 ++A K+P L+ Sbjct: 82 NIARKQPMLD 91 Score = 31.2 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 29/78 (37%), Gaps = 12/78 (15%) Query: 118 TLWM--TNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL++ + P+ +R + L + R A++ E A V Sbjct: 17 TLYVYGEDMTPTL----LRGAFSPFGNI------IDLSMDPPRNCAFVTYEKMESADQAV 66 Query: 176 EKLNGLKIEGYTLVTKVS 193 +LNG ++E L ++ Sbjct: 67 AELNGTQVESVQLKVNIA 84 >2CPD-A nrPDB Length = 99 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN-KDSAERAL 270 + +RNL +E + +E P + AF+ F N +D+ E Sbjct: 18 LYVRNLMLSTSEEMIEKEFNNIK--------PGAVERVKKIRDYAFVHFSNREDAVEAMK 69 Query: 271 QMNRSLLGNREISVSLA 287 +N +L I V+LA Sbjct: 70 ALNGKVLDGSPIEVTLA 86 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 10/88 (11%) Query: 119 LWMTNFPPSYTQRNIRDLLQDI--NVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVE 176 L++ N S ++ I +I V R R +A++ +++EDA ++ Sbjct: 18 LYVRNLMLSTSEEMIEKEFNNIKPGAVE--------RVKKIRDYAFVHFSNREDAVEAMK 69 Query: 177 KLNGLKIEGYTLVTKVSNPLEKSKRTDS 204 LNG ++G + ++ P++K S Sbjct: 70 ALNGKVLDGSPIEVTLAKPVDKDSSGPS 97 >6C8U-1 nrPDB Length = 115 Score = 38.9 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 9/77 (11%), Positives = 28/77 (36%), Gaps = 1/77 (1%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 +++ + ++RD + + + SR F ++ + + Sbjct: 27 MFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQP 86 Query: 179 NGLKIEGYTLVTKVSNP 195 + +++ T+ KV+ P Sbjct: 87 HH-ELDSKTIDPKVAFP 102 >2EVZ-A nrPDB Length = 229 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 29/69 (42%), Gaps = 4/69 (5%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL ++N PPS ++ +++ L V F R+ A I + S E+A + Sbjct: 151 SATLHLSNIPPSVSEEDLKVLFSSNGGVVKGF----KFFQKDRKMALIQMGSVEEAVQAL 206 Query: 176 EKLNGLKIE 184 L+ + Sbjct: 207 IDLHNHDLG 215 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 72/176 (40%), Gaps = 26/176 (14%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL- 270 +++ NL+ E + L F +G ++++ I +KE+ A + + + A+ A+ Sbjct: 37 LLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKEN------ALVQMADGNQAQLAMS 90 Query: 271 QMNRSLLGNREISVSLADKKPF---LERNEVKRLLASRNSKEL--------ETLICLFPL 319 +N L + I ++L+ + E E + L + L + +FP Sbjct: 91 HLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFP- 149 Query: 320 SDKVSPSLICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGS 375 PS ++E+D++ +L S G + F+ + KM +I GS Sbjct: 150 -----PSATLHLSNIPPSVSEEDLK--VLFSSNGGVVKGFKFFQKDRKMALIQMGS 198 >1QM9-A nrPDB Length = 198 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 29/69 (42%), Gaps = 4/69 (5%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL ++N PPS ++ +++ L V F R+ A I + S E+A + Sbjct: 120 SATLHLSNIPPSVSEEDLKVLFSSNGGVVKGF----KFFQKDRKMALIQMGSVEEAVQAL 175 Query: 176 EKLNGLKIE 184 L+ + Sbjct: 176 IDLHNHDLG 184 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 35/176 (19%), Positives = 72/176 (40%), Gaps = 26/176 (14%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERAL- 270 +++ NL+ E + L F +G ++++ I +KE+ A + + + A+ A+ Sbjct: 6 LLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKEN------ALVQMADGNQAQLAMS 59 Query: 271 QMNRSLLGNREISVSLADKKPF---LERNEVKRLLASRNSKEL--------ETLICLFPL 319 +N L + I ++L+ + E E + L + L + +FP Sbjct: 60 HLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFP- 118 Query: 320 SDKVSPSLICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGS 375 PS ++E+D++ +L S G + F+ + KM +I GS Sbjct: 119 -----PSATLHLSNIPPSVSEEDLK--VLFSSNGGVVKGFKFFQKDRKMALIQMGS 167 >2DGQ-A nrPDB Length = 108 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 6/85 (7%) Query: 211 EIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDS---AE 267 ++ + + LDE L+ FE FG I ++ + + + CAF+ + +DS A+ Sbjct: 17 KLFVGQI-PRGLDEQDLKPLFEEFGRIYELTVLK-DRLTGLHKGCAFLTYCARDSALKAQ 74 Query: 268 RALQMNRSLLG-NREISVSLADKKP 291 AL ++L G NR I V A + Sbjct: 75 SALHEQKTLPGMNRPIQVKPAASEG 99 Score = 34.7 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 8/64 (12%), Positives = 25/64 (39%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++ P +++++ L ++ + L + A++ +++ A L Sbjct: 18 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 77 Query: 179 NGLK 182 + K Sbjct: 78 HEQK 81 >5YVG-X nrPDB Length = 528 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 40/111 (36%), Gaps = 11/111 (9%) Query: 190 TKVSNPLEKSKRTDSATLEGRE--IMIRNLSTELLDENLLRESFEGFGSIEKINIPA--- 244 K P ++ R DS I ++ L + E+ + + F+ G I+ Sbjct: 265 NKFGGPRDQGSRHDSEQDNSDNNTIFVQGLGENVTIES-VADYFKQIGIIKTNKKTGQPM 323 Query: 245 ----GQKEHSFNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKK 290 +E A + F++ SA+ A+ + I VS A ++ Sbjct: 324 INLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRR 374 >2KVI-A nrPDB Length = 96 Score = 37.0 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 36/86 (41%), Gaps = 12/86 (13%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERA 269 + I NL + + + L F +G I +INI N F+ F+N S A Sbjct: 11 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI---------KNAFGFIQFDNPQSVRDA 61 Query: 270 LQMNRSLLG-NRE--ISVSLADKKPF 292 ++ + ++ + VS ++ +P Sbjct: 62 IECESQEMNFGKKLILEVSSSNARPQ 87 Score = 35.5 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 33/83 (39%), Gaps = 9/83 (10%) Query: 119 LWMTNFP-PSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 L++ N P + ++ ++ + + ++ N F +I + + R +E Sbjct: 13 LFIGNLPLKNVSKEDLFRIFSPYGHI--------MQINIKNAFGFIQFDNPQSVRDAIEC 64 Query: 178 LNGLKIEGYTLVTKVSNPLEKSK 200 + G L+ +VS+ + + Sbjct: 65 ESQEMNFGKKLILEVSSSNARPQ 87 >3NNH-A nrPDB Length = 88 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFN---TSRRFAYIDVTSKEDARYCV 175 +++ P +++++++R+L + V I + R S+ ++ +++ A Sbjct: 6 MFVGQVPRTWSEKDLRELFEQYGAV-YEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 64 Query: 176 EKLNGLKI 183 L+ +K+ Sbjct: 65 NALHNMKV 72 >6FYY-r nrPDB Length = 274 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 7/85 (8%) Query: 117 CTLWMTNFPPSYTQRNIRD-LLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 CTL + + + ++R+ LL + + + SR A++ +S+E A + Sbjct: 191 CTLKIMQVNENADENSLREELLFPFAPIPRVSVVRNKETGKSRGLAFVTFSSEEVAEQAL 250 Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSK 200 L+G GY + +E SK Sbjct: 251 RFLDG---RGY---MNLILRVEWSK 269 Score = 31.2 bits (69), Expect = 0.96, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 42/101 (41%), Gaps = 2/101 (1%) Query: 191 KVSNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHS 250 +P + R + + I ++ + +L E F I ++++ KE Sbjct: 172 GARDPSSDAYRDSRERDDMCTLKIMQVNENADENSLREELLFPFAPIPRVSVVR-NKETG 230 Query: 251 FNNCCAFMVFENKDSAERALQ-MNRSLLGNREISVSLADKK 290 + AF+ F +++ AE+AL+ ++ N + V + K Sbjct: 231 KSRGLAFVTFSSEEVAEQALRFLDGRGYMNLILRVEWSKPK 271 >2XNQ-A nrPDB Length = 97 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 27/69 (39%), Gaps = 9/69 (13%) Query: 210 REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERA 269 + I NL + + + L F +G I +INI N F+ F+N S A Sbjct: 23 SRLFIGNLPLKNVSKEDLFRIFSPYGHIMQINI---------KNAFGFIQFDNPQSVRDA 73 Query: 270 LQMNRSLLG 278 ++ + Sbjct: 74 IECESQEMN 82 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 14/83 (16%), Positives = 33/83 (39%), Gaps = 10/83 (12%) Query: 112 SHLTECTLWMTNFP-PSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKED 170 SH+ L++ N P + ++ ++ + + ++ N F +I + + Sbjct: 19 SHMKS-RLFIGNLPLKNVSKEDLFRIFSPYGHI--------MQINIKNAFGFIQFDNPQS 69 Query: 171 ARYCVEKLNGLKIEGYTLVTKVS 193 R +E + G L+ +VS Sbjct: 70 VRDAIECESQEMNFGKKLILEVS 92 >6G90-B nrPDB Length = 300 Score = 36.6 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 24/77 (31%), Positives = 35/77 (45%), Gaps = 5/77 (6%) Query: 198 KSKRTDSATLEG---REIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNC 254 + D + R I I L LDE L++ F FG IEKI I K + Sbjct: 92 WNPNVDPHIKDTDPYRTIFIGRL-PYDLDEIELQKYFVKFGEIEKIRIVK-DKITQKSKG 149 Query: 255 CAFMVFENKDSAERALQ 271 AF+VF++ S++ A + Sbjct: 150 YAFIVFKDPISSKMAFK 166 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 5/61 (8%), Positives = 21/61 (34%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 T+++ P + ++ + + S+ +A+I ++ ++ Sbjct: 108 TIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKE 167 Query: 178 L 178 + Sbjct: 168 I 168 >5ZWN-Q nrPDB Length = 300 Score = 36.2 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 7/99 (7%) Query: 176 EKLNGLKIEGYTLVTKVSNPLEKSKRTDSATLEG---REIMIRNLSTELLDENLLRESFE 232 E + KI+ L+ + + D + R I I L LDE L++ F Sbjct: 72 EDIKLSKIKNAQLLDRRLQN--WNPNVDPHIKDTDPYRTIFIGRL-PYDLDEIELQKYFV 128 Query: 233 GFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 FG IEKI I K + AF+VF++ S++ A + Sbjct: 129 KFGEIEKIRIVK-DKITQKSKGYAFIVFKDPISSKMAFK 166 Score = 33.5 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 5/61 (8%), Positives = 21/61 (34%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 T+++ P + ++ + + S+ +A+I ++ ++ Sbjct: 108 TIFIGRLPYDLDEIELQKYFVKFGEIEKIRIVKDKITQKSKGYAFIVFKDPISSKMAFKE 167 Query: 178 L 178 + Sbjct: 168 I 168 >6QX9-1A nrPDB Length = 282 Score = 36.2 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 8/87 (9%) Query: 205 ATLEGREIMIRNLSTELLDENL---LRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFE 261 T I I NL+ ++ + L L F FG I I + K AF++F+ Sbjct: 5 ETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQ----AFVIFK 60 Query: 262 NKDSAERALQ-MNRSLLGNREISVSLA 287 SA AL+ M ++ + + A Sbjct: 61 EVSSATNALRSMQGFPFYDKPMRIQYA 87 >2RT3-A nrPDB Length = 97 Score = 36.2 bits (82), Expect = 0.031, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 +++ N P T+ IR+ L+ + ++ T R A++ + A V++ Sbjct: 20 NVFLGNLPNGITEDEIREDLEPFGPID------QIKIVTERNIAFVHFLNIAAAIKAVQE 73 Query: 178 L 178 L Sbjct: 74 L 74 >1JMT-A nrPDB Length = 104 Score = 35.9 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 40/95 (42%), Gaps = 4/95 (4%) Query: 194 NPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNN 253 NP S+ D ++ ++ + E + E E +G +E++N+ +H N Sbjct: 12 NPQNSSQSADGLRSAVSDVEMQE-HYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGN 70 Query: 254 CCAFMVFENKDSAERA-LQMNRSLLGNREISVSLA 287 + F ++ AE+A + +N + I L+ Sbjct: 71 VY--VKFRREEDAEKAVIDLNNRWFNGQPIHAELS 103 >4CQ1-A nrPDB Length = 196 Score = 35.5 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL ++N PPS + ++R L + + + + A + + + E+A + Sbjct: 119 SATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDH-----KMALLQMATVEEAIQAL 173 Query: 176 EKLNGLKIE 184 L+ + Sbjct: 174 IDLHNYNLG 182 >2DO0-A nrPDB Length = 114 Score = 35.5 bits (80), Expect = 0.052, Method: Composition-based stats. Identities = 11/79 (13%), Positives = 27/79 (34%), Gaps = 1/79 (1%) Query: 117 CTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVE 176 T+++ N + ++++ VV + L + SR + +A + Sbjct: 16 STVFVANLDYKVGWKKLKEVFSMAGVVVRADIL-EDKDGKSRGIGTVTFEQSIEAVQAIS 74 Query: 177 KLNGLKIEGYTLVTKVSNP 195 NG + + K+ Sbjct: 75 MFNGQLLFDRPMHVKMDER 93 >4WWM-A nrPDB Length = 91 Score = 34.7 bits (78), Expect = 0.077, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 39/63 (61%), Gaps = 2/63 (3%) Query: 327 LICQFLQEEIHINEKDIRKILLVSDFNGAIIIFRDSKFAAKMLMILNGSQFQGKVIRSGT 386 LI QF EI++N++++ ++L+ D +I+ ++ + +L+++NG + ++ R+ Sbjct: 10 LISQFNFREIYVNDRELLRVLVKIDSKKHLILNESNQLKSGILILINGKDW--RLYRNQL 67 Query: 387 IND 389 +ND Sbjct: 68 LND 70 >3P6Y-C nrPDB Length = 90 Score = 34.7 bits (78), Expect = 0.082, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 2/82 (2%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLP--SLRFNTSRRFAYIDVTSKEDARYCV 175 L++ N T ++ + + + V + + S+ FA + V S+ ++ + Sbjct: 3 ALYIGNLTWWTTDEDLTEAVHSLGVNDILEIKFFENRANGQSKGFALVGVGSEASSKKLM 62 Query: 176 EKLNGLKIEGYTLVTKVSNPLE 197 + L ++ G V SN LE Sbjct: 63 DLLPKRELHGQNPVVTPSNKLE 84 >2LCW-A nrPDB Length = 116 Score = 34.7 bits (78), Expect = 0.090, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 33/87 (37%), Gaps = 9/87 (10%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPA-------GQKEHSFNNCCAFMVFENKD 264 I ++ L + E+ + + F+ G I+ +E A + F++ Sbjct: 10 IFVQGLGENVTIES-VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPP 68 Query: 265 SAERALQ-MNRSLLGNREISVSLADKK 290 SA+ A+ + I VS A ++ Sbjct: 69 SAKAAIDWFDGKEFSGNPIKVSFATRR 95 >2CQH-A nrPDB Length = 93 Score = 34.7 bits (78), Expect = 0.091, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 30/69 (43%), Gaps = 7/69 (10%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L++ N P+ T ++R L D + L +A++D + A +E L Sbjct: 11 LYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKS------GYAFVDYPDQNWAIRAIETL 64 Query: 179 NG-LKIEGY 186 +G +++ G Sbjct: 65 SGKVELHGK 73 >2LA6-A nrPDB Length = 99 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 31/84 (36%), Gaps = 9/84 (10%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPA-------GQKEHSFNNCCAFMVFENKD 264 I ++ L + E+ + + F+ G I+ +E A + F++ Sbjct: 16 IFVQGLGENVTIES-VADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSFDDPP 74 Query: 265 SAERALQ-MNRSLLGNREISVSLA 287 SA+ A+ + I VS A Sbjct: 75 SAKAAIDWFDGKEFSGNPIKVSFA 98 >6D6V-H nrPDB Length = 542 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL++ PP +++ + + + ++ +++ L + FA+I+ S+E+A + Sbjct: 248 TLYIDFLPPKCSKQTLVSIFGNFRIININLPL-QKNSQLCQGFAFIEFFSEEEANQAL 304 >2MMY-A nrPDB Length = 97 Score = 33.5 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 35/97 (36%), Gaps = 9/97 (9%) Query: 204 SATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPA-------GQKEHSFNNCCA 256 S + I ++ L + + + E F+ G I+ K+ A Sbjct: 2 SHMSDNNTIFVQGLGEGVSTDQ-VGEFFKQIGIIKTNKKTGKPMINLYTDKDTGKPKGEA 60 Query: 257 FMVFENKDSAERALQ-MNRSLLGNREISVSLADKKPF 292 + F++ SA+ A+ + I VS A ++P Sbjct: 61 TVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPE 97 >2I2Y-A nrPDB Length = 150 Score = 33.2 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 32/81 (39%), Gaps = 8/81 (9%) Query: 211 EIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFEN-KDSAERA 269 ++ + NL L R FG + + AF+ FE+ +D+A+ Sbjct: 75 KVYVGNLGNNGNKTELER----AFGYYGPLRSVWVARNP---PGFAFVEFEDPRDAADAV 127 Query: 270 LQMNRSLLGNREISVSLADKK 290 +++ L + V L++ + Sbjct: 128 RELDGRTLCGCRVRVELSNGE 148 Score = 32.4 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 32/79 (40%), Gaps = 5/79 (6%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 +C +++ N + + + + S+ + FA+++ DA V Sbjct: 73 DCKVYVGNLGNNGNKTELERAFGYYGPLR-SVWVARN----PPGFAFVEFEDPRDAADAV 127 Query: 176 EKLNGLKIEGYTLVTKVSN 194 +L+G + G + ++SN Sbjct: 128 RELDGRTLCGCRVRVELSN 146 >2LKZ-A nrPDB Length = 95 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 6/77 (7%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALS-IRLPSLRFNT-SRRFAYIDVTSKEDARYCV 175 T+ + N P +I L +A++ IRL + +R FA++ ++S DA + Sbjct: 11 TIILRNIAPHTVVDSIMTALSPYASLAVNNIRLIKDKQTQQNRGFAFVQLSSAMDASQLL 70 Query: 176 EKLNG----LKIEGYTL 188 + L LKI+G T+ Sbjct: 71 QILQSLHPPLKIDGKTI 87 >2F9J-A nrPDB Length = 125 Score = 32.8 bits (73), Expect = 0.28, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 34/90 (37%), Gaps = 3/90 (3%) Query: 119 LWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKL 178 L + N P T + D+ + IR+ + +R AY+ DA+ + L Sbjct: 21 LMIRNLPYKITAEEMYDIFGKYGPIR-QIRVGN--TPETRGTAYVVYEDIFDAKNACDHL 77 Query: 179 NGLKIEGYTLVTKVSNPLEKSKRTDSATLE 208 +G + LV N ++ D+ E Sbjct: 78 SGFNVCNRYLVVLYYNANRAFQKMDTKKKE 107 >1J4G-A nrPDB Length = 248 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 28/81 (34%), Gaps = 14/81 (17%) Query: 201 RTDSATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVF 260 R AT + I NL L +E L + + + ++P Q+ A + Sbjct: 6 RLSGATSSSYGVFISNLRKALPNERKLYDI-----PLLRSSLPGSQR-------YALIHL 53 Query: 261 EN--KDSAERALQMNRSLLGN 279 N ++ A+ + + Sbjct: 54 TNYADETISVAIDVTNVYIMG 74 >3JB9-Y nrPDB Length = 388 Score = 32.4 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 24/123 (19%), Positives = 47/123 (38%), Gaps = 22/123 (17%) Query: 204 SATLEGREIMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENK 263 S + + + ++ E ++ F +G IE+I + + AF+ + N+ Sbjct: 168 SFLRQNYTLYVGGITPTDDIEEIVSRHFAEWGDIERIRVLN-------SRGIAFITYLNE 220 Query: 264 DSAERALQ-MNRSLLGNRE---ISVSLADKKP-----------FLERNEVKRLLASRNSK 308 +A+ A + M L + E + + D P N VK+LL + Sbjct: 221 ANAQFAKEAMAHQSLDHDECLNVRWATTDPNPASQARNQRRLEERAANAVKKLLPKQFLL 280 Query: 309 ELE 311 +LE Sbjct: 281 DLE 283 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 11/115 (9%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 TL++ P+ +I +++ I +R SR A+I ++ +A++ E Sbjct: 175 TLYVGGITPT---DDIEEIVSRHFAEWGDIE--RIRVLNSRGIAFITYLNEANAQFAKEA 229 Query: 178 LNGLKIEGYTLVTKV---SNPLEKSKRTDSATLEGREIMIRNLSTELLDENLLRE 229 + ++ + ++P S+ + LE R N +LL + L + Sbjct: 230 MAHQSLDHDECLNVRWATTDPNPASQARNQRRLEERA---ANAVKKLLPKQFLLD 281 >3GM8-A nrPDB Length = 801 Score = 31.6 bits (70), Expect = 0.69, Method: Composition-based stats. Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 273 NRSLLG-NREISVSLADKKPFLERNEVKRLLASRNSKELETLICLFPLSDKV 323 N S+ + +I VS AD FL + K LL S +S + TLIC +K+ Sbjct: 207 NGSIADTSEKIFVSSADSLCFLSGSIRKPLLWSPDSPNVYTLICQLTRDNKI 258 >5MDU-A nrPDB Length = 157 Score = 31.6 bits (70), Expect = 0.74, Method: Composition-based stats. Identities = 13/76 (17%), Positives = 28/76 (36%), Gaps = 6/76 (7%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCV 175 TL++ S + +R + + V SL N + R ++ + ++ A Sbjct: 22 SRTLFLGGITRSVREPVLRSMFERFGSVQ------SLILNHNYRHGFLKMFRRDAAEKAQ 75 Query: 176 EKLNGLKIEGYTLVTK 191 + + T+ TK Sbjct: 76 VAMENVPFADTTIRTK 91 >2MKI-A nrPDB Length = 203 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 25/179 (13%), Positives = 55/179 (30%), Gaps = 16/179 (8%) Query: 119 LWMTNFPPSYTQRNIRDLLQDIN--VVALSIRLPSLRFNTSRRFAYIDVTSKEDA----R 172 +++ PP + I + +V + S + + +A++ + Sbjct: 15 VFVGGLPPDIDEDEITASFRRFGPLIVDWPHKAESKSYFPPKGYAFLLFQDESSVQALID 74 Query: 173 YCVEKLNGLKI--EGYTLVTKVSNPLEKSKRTDSATLEGRE-------IMIRNLSTELLD 223 C+E+ L + T+ K + ++G + I + + L Sbjct: 75 ACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRA 134 Query: 224 ENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLLGNREI 282 L +G + I E + + F N+ S A+ L + EI Sbjct: 135 VELAMIMDRLYGGVCYAGI-DTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGEI 192 >5WSG-X nrPDB Length = 111 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 32/82 (39%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEK 177 TL+++ + +R L + + S+ F R A+I + + + A Sbjct: 29 TLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFKKQRGQAFITMRTIDQASLAQIS 88 Query: 178 LNGLKIEGYTLVTKVSNPLEKS 199 LNG + G L + S K+ Sbjct: 89 LNGERFFGKPLKVEFSKSETKT 110 >2M2B-A nrPDB Length = 131 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 51/110 (46%), Gaps = 9/110 (8%) Query: 118 TLWMTNFPPSYTQRNIRDLLQDINVVALS--IRLPSLRFNTSRRFAYIDVTSKEDAR--Y 173 T+ + N P T +I L V++ S + + +R FA+I +++ E A+ Sbjct: 25 TIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIEAAQLLQ 84 Query: 174 CVEKLN-GLKIEGYTLVTKVSNPLEKSKRTDSATLEGREIMIRNLSTELL 222 ++ L+ L I+G T+ + K + D A+ EG I ++++ + Sbjct: 85 ILQALHPPLTIDGKTINVE----FAKGSKRDMASNEGSRISAASVASTAI 130 >2CPE-A nrPDB Length = 113 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 28/86 (32%), Gaps = 8/86 (9%) Query: 116 ECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRL--------PSLRFNTSRRFAYIDVTS 167 +++ S T ++ D + VV ++ R + A + Sbjct: 15 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 74 Query: 168 KEDARYCVEKLNGLKIEGYTLVTKVS 193 A+ VE +G +G L ++ Sbjct: 75 PPTAKAAVEWFDGKDFQGSKLKVSLA 100 >2VR2-A nrPDB Length = 541 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 13/102 (12%) Query: 340 EKDIRKILLVSDFNGAI-IIFRDSKFAAKMLMIL--NGSQFQGKVIRSGTINDMKRYYNN 396 E +R I + S N + I+ SK AAK++ +G G+ I + D Y+N Sbjct: 250 EATLRAITIASAVNCPLYIVHVMSKSAAKVIADARRDGKVVYGEPIAASLGTDGTHYWNK 309 Query: 397 QQNHSMKHVKPSCINMMEKGPNLQVKKKIPD-KQEQMSNDDF 437 + +H+ HV GP L+ PD ++NDD Sbjct: 310 EWHHAAHHV---------MGPPLRPDPSTPDFLMNLLANDDL 342 >5OSG-h nrPDB Length = 235 Score = 29.7 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 34/90 (37%), Gaps = 13/90 (14%) Query: 212 IMIRNLSTELLDENLLRESFEGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQ 271 + ++N T + + F G + K+ + A + FEN + ++A+ Sbjct: 57 VYVKNWGTGSVADAT--NVFSAAGKVVKVQL--------RRQRYALVFFENSAAVKKAID 106 Query: 272 M-NRSLLGNREISV--SLADKKPFLERNEV 298 + N + + + V + A KP N Sbjct: 107 LFNEKEVLGQTVLVVPAKASPKPDAHENSS 136 >1UM9-A nrPDB Length = 367 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 32/83 (38%), Gaps = 8/83 (9%) Query: 97 ITKTHKVVGQNEIIVSHLTECTLWMTNFPPSYTQRNIRDLLQDINVVALSIRLPSLRFNT 156 + +TH+ E + + E W+ +FP +R L +D+ L+ R+ R+ Sbjct: 2 VKETHRFETFTEEPIRLIGEEGEWLGDFPLDLEGEKLRRLYRDM----LAARMLDERYTI 57 Query: 157 SRRFAYIDVTS----KEDARYCV 175 R + E A+ + Sbjct: 58 LIRTGKTSFIAPAAGHEAAQVAI 80 >4YEW-A nrPDB Length = 90 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 13/68 (19%), Positives = 23/68 (33%) Query: 232 EGFGSIEKINIPAGQKEHSFNNCCAFMVFENKDSAERALQMNRSLLGNREISVSLADKKP 291 G I + + + A + F ERA R+ +EI+++ A Sbjct: 19 AAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAASTGRNPQTGKEITIAAAKVPS 78 Query: 292 FLERNEVK 299 F +K Sbjct: 79 FRAGKALK 86 >6FYY-p nrPDB Length = 763 Score = 28.2 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 7/51 (13%), Positives = 19/51 (37%) Query: 133 IRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKI 183 + L V ++ F +++ S DA+ ++ +G ++ Sbjct: 99 LTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRL 149 >3NS5-A nrPDB Length = 91 Score = 28.2 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 7/51 (13%), Positives = 19/51 (37%) Query: 133 IRDLLQDINVVALSIRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKI 183 + L V ++ F +++ S DA+ ++ +G ++ Sbjct: 29 LTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRL 79 >4NOX-A nrPDB Length = 746 Score = 27.8 bits (60), Expect = 8.9, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 147 IRLPSLRFNTSRRFAYIDVTSKEDARYCVEKLNGLKIEGYTLVTKVSNPLEKSKRTDSAT 206 I +P S RFA+++ +S +A V +L+ + L K + + K D Sbjct: 79 IYMPMGDDGMSLRFAFVEYSSPAEASAAVRQLDYV-----PLDKKHTLRVNKLTDIDRYG 133 Query: 207 LEGR 210 EGR Sbjct: 134 REGR 137 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.130 0.339 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,512,966 Number of Sequences: 36641 Number of extensions: 570380 Number of successful extensions: 1871 Number of sequences better than 10.0: 115 Number of HSP's better than 10.0 without gapping: 89 Number of HSP's successfully gapped in prelim test: 68 Number of HSP's that attempted gapping in prelim test: 1615 Number of HSP's gapped (non-prelim): 250 length of query: 444 length of database: 10,336,785 effective HSP length: 100 effective length of query: 344 effective length of database: 6,672,685 effective search space: 2295403640 effective search space used: 2295403640 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.1 bits)