BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P49862 (253 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3BSQ-A nrPDB 464 e-131 5ZFH-A nrPDB 372 e-104 2PSX-A nrPDB 225 1e-59 1NPM-A nrPDB 221 3e-58 5MS3-A nrPDB 209 8e-55 1UTJ-A nrPDB 208 1e-54 5FXL-A nrPDB 207 3e-54 1SGF-G nrPDB 207 4e-54 5LPF-A nrPDB 204 3e-53 1F7Z-A nrPDB 203 5e-53 2BDH-A nrPDB 202 8e-53 4AN7-A nrPDB 200 6e-52 1TON-A nrPDB 199 1e-51 1SPJ-A nrPDB 194 4e-50 1AO5-A nrPDB 193 7e-50 6QHB-A nrPDB 192 2e-49 1A0J-A nrPDB 191 3e-49 4NFE-A nrPDB 191 3e-49 1SGF-A nrPDB 190 5e-49 2TLD-E nrPDB 190 5e-49 4WWY-A nrPDB 187 3e-48 5C67-A nrPDB 183 5e-47 2EEK-A nrPDB 182 1e-46 3QUM-P nrPDB 181 2e-46 1GVZ-A nrPDB 160 4e-40 1FXY-A nrPDB 157 4e-39 2AIQ-A nrPDB 154 2e-38 2CGA-A nrPDB 150 4e-37 1EUF-A nrPDB 150 7e-37 4GSO-A nrPDB 149 1e-36 4Q7Y-A nrPDB 148 2e-36 3S69-A nrPDB 147 6e-36 1OP0-A nrPDB 146 9e-36 1NN6-A nrPDB 146 1e-35 1BQY-A nrPDB 145 2e-35 4E7N-A nrPDB 140 4e-34 3S9B-A nrPDB 138 2e-33 5XRF-A nrPDB 135 2e-32 1FI8-A nrPDB 135 2e-32 3F6U-H nrPDB 134 4e-32 1SC8-U nrPDB 134 5e-32 3DFJ-A nrPDB 132 2e-31 3E0N-B nrPDB 132 2e-31 3G01-A nrPDB 131 2e-31 1MZD-A nrPDB 129 1e-30 4XDE-A nrPDB 127 4e-30 3RP2-A nrPDB 127 5e-30 5TJX-A nrPDB 126 1e-29 1BDA-A nrPDB 125 1e-29 5LHN-A nrPDB 125 2e-29 2PKA-B nrPDB 125 2e-29 1IAU-A nrPDB 125 2e-29 3T2N-A nrPDB 125 2e-29 2RDL-A nrPDB 125 3e-29 4MPW-A nrPDB 124 5e-29 4DGJ-A nrPDB 123 7e-29 2F91-A nrPDB 123 7e-29 1A5I-A nrPDB 123 1e-28 1KYN-A nrPDB 122 1e-28 3TK9-A nrPDB 122 1e-28 6I44-A nrPDB 122 2e-28 1P57-B nrPDB 122 2e-28 5O32-I nrPDB 122 2e-28 2XRC-A nrPDB 121 2e-28 1ORF-A nrPDB 121 2e-28 1YC0-A nrPDB 121 2e-28 1LTO-A nrPDB 120 4e-28 2R0L-A nrPDB 120 4e-28 5GVT-A nrPDB 120 8e-28 3W94-A nrPDB 118 3e-27 1EKB-B nrPDB 116 7e-27 6AOD-C nrPDB 116 7e-27 5UGG-A nrPDB 115 2e-26 1PQ7-A nrPDB 114 3e-26 2F83-A nrPDB 114 4e-26 1Q3X-A nrPDB 114 6e-26 4Z6A-H nrPDB 113 6e-26 4DJZ-B nrPDB 113 8e-26 4IGD-A nrPDB 113 9e-26 2OQ5-A nrPDB 113 1e-25 1FDP-A nrPDB 112 1e-25 1ZJK-A nrPDB 112 1e-25 5FCR-A nrPDB 112 2e-25 4FXG-H nrPDB 112 2e-25 1KIG-H nrPDB 112 2e-25 4DUR-A nrPDB 110 5e-25 5XW8-A nrPDB 110 8e-25 1MKW-K nrPDB 109 9e-25 3P8G-A nrPDB 109 1e-24 3NXP-A nrPDB 108 2e-24 3K65-B nrPDB 108 2e-24 1ETT-H nrPDB 108 2e-24 2OCV-B nrPDB 108 3e-24 1BRU-P nrPDB 108 3e-24 4NZQ-A nrPDB 107 3e-24 2OLG-A nrPDB 106 7e-24 1AZZ-A nrPDB 106 9e-24 1C5M-D nrPDB 106 1e-23 1FIW-A nrPDB 105 2e-23 1VR1-H nrPDB 104 3e-23 2XXL-A nrPDB 103 6e-23 1FIZ-A nrPDB 103 9e-23 1EQ9-A nrPDB 102 1e-22 2ZKS-A nrPDB 102 2e-22 1AE5-A nrPDB 102 2e-22 1SI5-H nrPDB 100 4e-22 5TO3-B nrPDB 100 9e-22 1X7A-C nrPDB 100 1e-21 4LK4-A nrPDB 100 1e-21 3LC3-A nrPDB 99 1e-21 3I77-A nrPDB 99 2e-21 1FUJ-A nrPDB 99 2e-21 5KWM-A nrPDB 98 3e-21 1AKS-B nrPDB 94 4e-20 1ELT-A nrPDB 94 7e-20 2ASU-B nrPDB 93 1e-19 1PYT-D nrPDB 92 2e-19 6BQM-A nrPDB 92 2e-19 4IW4-E nrPDB 92 2e-19 2B9L-A nrPDB 92 2e-19 3VGC-B nrPDB 92 3e-19 1FON-A nrPDB 90 1e-18 4KKD-A nrPDB 89 2e-18 1YM0-A nrPDB 88 3e-18 3BEU-A nrPDB 88 4e-18 4H4F-A nrPDB 87 5e-18 2V35-A nrPDB 87 8e-18 2QY0-B nrPDB 86 2e-17 1GPZ-A nrPDB 86 2e-17 2JET-B nrPDB 85 3e-17 1ELV-A nrPDB 85 3e-17 1MD7-A nrPDB 85 3e-17 2HLC-A nrPDB 85 4e-17 5UBM-A nrPDB 85 4e-17 3H7T-A nrPDB 83 1e-16 2KAI-A nrPDB 82 3e-16 4J1Y-A nrPDB 82 3e-16 2FMJ-A nrPDB 81 4e-16 1PPF-E nrPDB 80 8e-16 1M9U-A nrPDB 79 2e-15 4BXW-A nrPDB 75 2e-14 4X0L-C nrPDB 75 2e-14 4WJG-C nrPDB 75 3e-14 4F4O-C nrPDB 73 1e-13 3H7O-A nrPDB 68 4e-12 1RIW-B nrPDB 66 2e-11 3RU4-E nrPDB 66 2e-11 1BBR-H nrPDB 64 5e-11 1EPT-B nrPDB 63 1e-10 2JET-C nrPDB 62 2e-10 2I6S-A nrPDB 62 2e-10 2HNT-F nrPDB 54 5e-08 1DLE-A nrPDB 53 1e-07 1BBR-E nrPDB 53 1e-07 2WIN-I nrPDB 53 1e-07 2OK5-A nrPDB 52 2e-07 2HNT-C nrPDB 48 5e-06 3F1S-B nrPDB 41 4e-04 3H5C-B nrPDB 40 0.001 4EXK-A nrPDB 34 0.048 4XZ3-B nrPDB 32 0.18 2OCI-A nrPDB 32 0.27 4G7Y-S nrPDB 31 0.58 4G80-S nrPDB 30 0.91 2VOR-A nrPDB 30 1.2 6HQB-A nrPDB 29 2.3 5MRT-A nrPDB 28 2.5 4FE1-A nrPDB 27 6.0 >3BSQ-A nrPDB Length = 227 Score = 464 bits (1194), Expect = e-131, Method: Compositional matrix adjust. Identities = 222/224 (99%), Positives = 222/224 (99%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 60 Query: 90 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 149 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW Sbjct: 61 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 120 Query: 150 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 209 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL Sbjct: 121 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 180 Query: 210 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK H Sbjct: 181 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKHHH 224 >5ZFH-A nrPDB Length = 224 Score = 372 bits (955), Expect = e-104, Method: Compositional matrix adjust. Identities = 170/224 (75%), Positives = 194/224 (86%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 IIDG C GSHPWQVALL GNQLHCGGVLV++ WVLTAAHCKM +Y V LGSD +GD+ Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGDQS 60 Query: 90 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 149 AQ+IKA+KSFRHPGYST+THVND+MLV+L+ ++SS V+ V+LP CEPPGT+CTVSGW Sbjct: 61 AQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEPPGTSCTVSGW 120 Query: 150 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 209 GTTTSPDVTFPSDLMC DVKLIS ++C KVYKDLL +MLCAGIPDSK N CNGDSGGPL Sbjct: 121 GTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTCNGDSGGPL 180 Query: 210 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 VC TLQGLVSWGT+PCGQPNDPGVYTQVCK+ +W+ +TMK HR Sbjct: 181 VCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTHR 224 >2PSX-A nrPDB Length = 227 Score = 225 bits (574), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 109/225 (48%), Positives = 149/225 (66%), Gaps = 5/225 (2%) Query: 30 IIDGAPCARGSHPWQVALL-SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG-- 86 II+G+ C + PWQ ALL NQL+CG VLV+ +W+LTAAHC+ + V LG +L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 + Q + KS HPGYS H NDLML+KLN + R + V+ + + S C GT C Sbjct: 61 YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 120 Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205 VSGWGTT SP V FP L C+++ ++S + C Y ++++M CAG + +++C GDS Sbjct: 121 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRDSCQGDS 179 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 GGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++ Sbjct: 180 GGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 224 >1NPM-A nrPDB Length = 225 Score = 221 bits (562), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 106/225 (47%), Positives = 143/225 (63%), Gaps = 6/225 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I++G C S PWQ AL G +L CGGVLV +RWVLTAAHCK +Y+V LG +L D Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 88 RRAQRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + Q I+ ++S +HP Y+ + H +D+ML++L + A L VK V+L + C G C Sbjct: 61 QPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKVGQKC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 +SGWGT TSP FP+ L C +VK+ S C + Y + M+CAG + + C GD Sbjct: 121 IISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGA-DTCQGD 179 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 SGGPLVC G LQG+ SWG+ PCG+P PGVYT++C++T WI TM Sbjct: 180 SGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >5MS3-A nrPDB Length = 228 Score = 209 bits (533), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 108/227 (47%), Positives = 136/227 (59%), Gaps = 10/227 (4%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 ++ G C S PWQ AL G QL CGGVLV WVLTAAHCK +YTV LG +L ++ Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 90 A--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 Q I +S HP Y++ + H +DLML++L QA L S VK + L C PG C Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNA--CN 202 TVSGWGT TSP FP L C +VK+ + C Y + + M+CAG S K A C Sbjct: 121 TVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG---SSKGADTCQ 177 Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++ WI + Sbjct: 178 GDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >1UTJ-A nrPDB Length = 242 Score = 208 bits (530), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 106/244 (43%), Positives = 146/244 (59%), Gaps = 5/244 (2%) Query: 11 ILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70 I L+ + L A + DKI+ G C S P QV+L SG CGG LVNE WV++AAH Sbjct: 2 ISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSLNSGYHF-CGGSLVNENWVVSAAH 60 Query: 71 CKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 C + V LG + + Q I +S+ RHP YS+ ND+ML+KL+ A L++ V Sbjct: 61 CYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYV 120 Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM 188 + V LP+ C P GT CTVSGWG T S + L C+++ ++S DC Y ++ N+M Sbjct: 121 QPVALPTSCAPAGTMCTVSGWGNTMSSTAD-SNKLQCLNIPILSYSDCNNSYPGMITNAM 179 Query: 189 LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 CAG + K++C GDSGGP+VC G LQG+VSWG + C +P +PGVY +VC F W+ T Sbjct: 180 FCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFNDWLTST 238 Query: 249 MKKH 252 M + Sbjct: 239 MASY 242 >5FXL-A nrPDB Length = 246 Score = 207 bits (528), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 104/244 (42%), Positives = 141/244 (57%), Gaps = 4/244 (1%) Query: 11 ILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70 I L L A DKI+ G C + P+QV+L SG CGG L+N +WV++AAH Sbjct: 5 IFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHF-CGGSLINSQWVVSAAH 63 Query: 71 CKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 C + V LG D + + Q I ASKS HP Y++ T ND+ML+KL S A L+S V Sbjct: 64 CYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRV 123 Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM 188 + LP+ C GT C +SGWG T S ++P L C+ ++S C Y + ++M Sbjct: 124 ASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNM 183 Query: 189 LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 CAG + K++C GDSGGP+VC G LQG+VSWG+ C Q N PGVYT+VC + WI T Sbjct: 184 FCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYTKVCNYVSWIKQT 242 Query: 249 MKKH 252 + + Sbjct: 243 IASN 246 >1SGF-G nrPDB Length = 237 Score = 207 bits (527), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 105/236 (44%), Positives = 144/236 (61%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S PW VA+ Q CGGVL++ WVLTAAHC + Y V LG + L + Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 88 RRAQRIKASKSFRHPGYST---QTHV--------NDLMLVKLNSQARLSSMVKKVRLPSR 136 AQ SK+ HPG++ + H+ NDLML++L+ A ++ VK + LP+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 G+TC SGWG+ T F DL CV++KL+ +DC K + + + ++MLCAG D Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPL+C G LQG+ SWG PCG+P+ PGVYT++ KFT WI DTM K+ Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKN 236 >5LPF-A nrPDB Length = 234 Score = 204 bits (519), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 98/229 (42%), Positives = 140/229 (61%), Gaps = 10/229 (4%) Query: 33 GAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQR 92 G+PCARGS PWQV+L +G HC GVLV++ WVLTAAHC +G D L + ++ Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQ 66 Query: 93 IK-ASKSFRHPGYST--------QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTT 143 ++ ++S HP Y +T +DLML+KL L V+ ++LP RC PG Sbjct: 67 LRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQ 126 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG 203 C V+GWGTT + V + L C + ++SP++C Y ++ N+M+CAG+ D ++ C Sbjct: 127 CQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGL-DRGQDPCQS 185 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 DSGGPLVC TLQG++SWG +PCG P VYTQ+CK+ WIN ++ + Sbjct: 186 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >1F7Z-A nrPDB Length = 233 Score = 203 bits (517), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 98/227 (43%), Positives = 139/227 (61%), Gaps = 4/227 (1%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86 D I+ G C S P+QV+L SG CGG L+N++WV++AAHC + V LG + Sbjct: 9 DAIVGGYTCQENSVPYQVSLNSGYHF-CGGSLINDQWVVSAAHCYKSRIQVRLGEHNINV 67 Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 + Q + A+K +HP + +T ND+ML+KL+S +L++ V V LPS C P GT C Sbjct: 68 LEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCAPAGTQCL 127 Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205 +SGWG T S V P L C+D L+ DC Y + ++M+C G + K++C GDS Sbjct: 128 ISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGKDSCQGDS 187 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GGP+VC G LQG+VSWG + C P++PGVYT+VC + WI DT+ + Sbjct: 188 GGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >2BDH-A nrPDB Length = 223 Score = 202 bits (515), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 106/224 (47%), Positives = 145/224 (64%), Gaps = 5/224 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL-GDR 88 II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC N YT+ LG +L D+ Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 89 R--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 +Q ++AS S RHP Y+ NDLML+KL+ S ++ + + S+C G +C V Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 SGWG + P+ L CV+V ++S + C+K+Y L SM CAG +K++CNGDSG Sbjct: 121 SGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSG 178 Query: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 GPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++ Sbjct: 179 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQ 222 >4AN7-A nrPDB Length = 231 Score = 200 bits (508), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 99/227 (43%), Positives = 136/227 (59%), Gaps = 4/227 (1%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86 DKI+ G CA S P+QV+L SG+ CGG L+N +WV++AAHC + V LG + Sbjct: 7 DKIVGGYTCAANSIPYQVSLNSGSHF-CGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV 65 Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 + Q I A+K HP ++ T ND+ML+KL+S A L+S V V LP C GT C Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECL 125 Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205 +SGWG T S ++PS L C+ ++S C Y + +M+C G + K++C GDS Sbjct: 126 ISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQGDS 185 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GGP+VC G LQG+VSWG + C Q N PGVYT+VC + WI T+ + Sbjct: 186 GGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >1TON-A nrPDB Length = 235 Score = 199 bits (505), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 100/236 (42%), Positives = 139/236 (58%), Gaps = 15/236 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S PWQVA++ N+ CGGVL++ WV+TAAHC N Y V LG + L + Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 88 RRAQRIKASKSFRHPGY-----------STQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 AQR +SFRHP Y H NDLML+ L+ A ++ VK + LP++ Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 G+TC SGWG+T ++ DL CV++ L+S + C + YKD + + MLCAG + Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPL+C G LQG+ S G PC +P P +Y ++ KFT WI MK++ Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKEN 234 >1SPJ-A nrPDB Length = 238 Score = 194 bits (492), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 97/237 (40%), Positives = 137/237 (57%), Gaps = 14/237 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 I+ G C + S PWQ AL + CGG+LV+ +WVLTAAHC + Y + LG L D Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 90 --AQRIKASKSFRHPGY-----------STQTHVNDLMLVKLNSQAR-LSSMVKKVRLPS 135 AQ + S+SF HPG+ + + + +DLML++L A ++ VK V LP+ Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195 G+TC SGWG+ + +FP DL CVD+K++ +C K + + + MLC G + Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPL+C G LQG+ SWG PCG PN P V +V + KWI DT+ ++ Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >1AO5-A nrPDB Length = 237 Score = 193 bits (490), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 98/236 (41%), Positives = 137/236 (58%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 ++ G C + S PWQVA+ + CGGVL++ WVLTAAHC +++Y V LG + L Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 90 --AQRIKASKSFRHPGYSTQTHV-----------NDLMLVKLNSQARLSSMVKKVRLPSR 136 AQ SKSF HPG++ + +DLML++L+ A ++ +VK + LP++ Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 PG+ C SGWG+ T P DL CV + L+ ++C KVY + + MLCAG Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C DSGGPL+C G LQG S+G PCG+P P +YT + KF WI DTM K+ Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >6QHB-A nrPDB Length = 223 Score = 192 bits (487), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 94/223 (42%), Positives = 133/223 (59%), Gaps = 4/223 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 ++ G PC + SHP+Q AL + L CGGVL++ WVLTAAHCK V LG LG + Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQE 60 Query: 90 AQRIKAS--KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 + + ++S ++ HP Y +H D+ML++L A+LS +++ + L C T+C + Sbjct: 61 SSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHIL 120 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T D FP + C + L+S ++C Y + +MLCAG K++C GDSGG Sbjct: 121 GWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGG 178 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 PLVC L+GLVSWG PCG PGVYT VC++T WI T++ Sbjct: 179 PLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 221 >1A0J-A nrPDB Length = 223 Score = 191 bits (485), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 93/225 (41%), Positives = 131/225 (58%), Gaps = 4/225 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C + S +Q +L SG CGG L++ WV++AAHC + V LG + + Sbjct: 1 IVGGYECRKNSASYQASLQSGYHF-CGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I + K HP Y+++ ND+ML+KL+ A L+S V V LPS C GT C VS Sbjct: 60 GTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASSGTRCLVS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG + +P L C+D+ ++S C Y + ++M CAG + K++C GDSGG Sbjct: 120 GWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSCQGDSGG 179 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 P+VC G LQG+VSWG + C Q N PGVYT+VC + WI+ TM + Sbjct: 180 PVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >4NFE-A nrPDB Length = 237 Score = 191 bits (484), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 99/233 (42%), Positives = 132/233 (56%), Gaps = 13/233 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 I+ G C + S PWQVA+ S HCGGVLV+ +WVLTAAHC V LG L + Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 90 --AQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 QR+ S SF HP Y+ + +DLML++L+ A+++ +VK + LP++ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 GTTC SGWG+ + P L CV + L+S C + Y + + MLCAG+ Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 K+ C GDSGGPLVC G LQG+ SWG PC P P VYT+V + KWI DT+ Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 233 >1SGF-A nrPDB Length = 240 Score = 190 bits (483), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 93/225 (41%), Positives = 133/225 (59%), Gaps = 13/225 (5%) Query: 38 RGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GDRRAQRIKA 95 S PW VA+ N+ CGGVL++ WVLTAAHC ++Y V LG + + Q Sbjct: 12 ENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLV 71 Query: 96 SKSFRHPGYS-----------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 SK+ HP ++ + NDLML++L+ A ++ +VK + LP+ G+TC Sbjct: 72 SKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTC 131 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 SGWG+TT +P DL CV++KL+ +DC K ++ + ++MLCAG D C D Sbjct: 132 LASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHD 191 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 SGGPL+C G LQG+ SWG PCG+P +P VYT++ KF+ WI +TM Sbjct: 192 SGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETM 236 >2TLD-E nrPDB Length = 220 Score = 190 bits (482), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 96/225 (42%), Positives = 134/225 (59%), Gaps = 7/225 (3%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C + P+QV+L SG CGG L+N +WV++AAHC + V LG D + + Sbjct: 1 IVGGYTCGANTVPYQVSLNSGYHF-CGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I ASKS HP Y++ T ND+ML+KL S A L+S V + LP+ C GT C +S Sbjct: 60 GNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLIS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S ++P L C+ ++S C Y + ++M CAG+ ++C GDSGG Sbjct: 120 GWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG--DSCQGDSGG 177 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 P+VC G LQG+VSWG+ C + N PGVYT+VC + WI T+ + Sbjct: 178 PVVCSGKLQGIVSWGS-GCAK-NKPGVYTKVCNYVSWIKQTIASN 220 >4WWY-A nrPDB Length = 224 Score = 187 bits (476), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 93/222 (41%), Positives = 132/222 (59%), Gaps = 4/222 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C S P+QV+L SG CGG L+NE+WV++A HC + V LG + + Sbjct: 1 IVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I A+K RHP Y +T ND+ML+KL+S+A +++ V + LP+ GT C +S Sbjct: 60 GNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPATGTKCLIS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S +P +L C+D ++S C Y + ++M C G + K++C DSGG Sbjct: 120 GWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQRDSGG 179 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 P+VC G LQG+VSWG C Q N PGVYT+V + KWI +T+ Sbjct: 180 PVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTI 220 >5C67-A nrPDB Length = 224 Score = 183 bits (465), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 92/222 (41%), Positives = 131/222 (59%), Gaps = 4/222 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C S P+QV+L SG+ CGG L++E+WV++AAHC V LG + + Sbjct: 1 IVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C +S Sbjct: 60 GNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLIS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S +P +L C+D +++ +C Y + NSM C G + K++C D+GG Sbjct: 120 GWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDAGG 179 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 P+VC G LQG+VSWG C N PGVYT+V + WI DT+ Sbjct: 180 PVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTI 220 >2EEK-A nrPDB Length = 220 Score = 182 bits (462), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 95/222 (42%), Positives = 128/222 (57%), Gaps = 5/222 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S QV+L SG CGG LV++ WV++AAHC + V LG + + Sbjct: 1 IVGGYECTKHSQAHQVSLNSGYHF-CGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I +S RHP YS+ ND+ML+KL A L+ V V LP+ C T CTVS Sbjct: 60 GTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADATMCTVS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S V L C+ + ++S DC Y ++ SM CAG + K++C GDSGG Sbjct: 120 GWGNTMS-SVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQGDSGG 178 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 P+VC G LQG+VSWG + C + + PGVY +VC + W+ DTM Sbjct: 179 PVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTM 219 >3QUM-P nrPDB Length = 237 Score = 181 bits (460), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 98/233 (42%), Positives = 131/233 (56%), Gaps = 13/233 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L + Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 88 RRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPSR 136 Q + S SF HP Y N DLML++L+ A L+ VK + LP++ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+ Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 233 >1GVZ-A nrPDB Length = 237 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 88/236 (37%), Positives = 126/236 (53%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 II G C + S PWQVA+ CGGVLV+ +WVLTAAHC ++Y + LG L + Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 88 RRAQRIKASKSFRHPGYS-----------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 AQ + S SF P + +DLML++L AR++ VK + LP++ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 G+TC SGWG ++ L CV+++L S + C + Y + + +LCA D Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 + C GDSGG L+C G QG+ SWG C ND V+T+V KWI +T++K+ Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >1FXY-A nrPDB Length = 228 Score = 157 bits (397), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 80/228 (35%), Positives = 124/228 (54%), Gaps = 12/228 (5%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88 I+ G C G PWQ L++ N+ CGG +++E ++LTAAHC Y +GDR Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCL---YQAKRFKVRVGDR 57 Query: 89 RAQRIKASKS-------FRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPG 141 ++ + ++ +H ++ +T+ D+ +++L + V LP+ G Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPATG 117 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 T C +SGWG T S +P +L C+D ++S C Y + ++M C G + K++C Sbjct: 118 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 177 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GDSGGP+VC G LQG+VSWG C Q N PGVYT+V + KWI +T+ Sbjct: 178 QGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTI 224 >2AIQ-A nrPDB Length = 231 Score = 154 bits (390), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 83/223 (37%), Positives = 116/223 (52%), Gaps = 5/223 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGS---DTLG 86 +I G C H + +AL+ N CGG L+N+ WVLTA HC ++LG L Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 +R K F + D+ML++LN R S+ + + LPS G+ C + Sbjct: 60 KDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRI 119 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 GWGT TSP+ T P C ++ ++ C YK L + LCAGI + K+ C GDSG Sbjct: 120 MGWGTITSPNATLPDVPHCANINILDYAVCQAAYKGLAA-TTLCAGILEGGKDTCKGDSG 178 Query: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GPL+C G QG++S G PC QP PG+YT+V +T WI + Sbjct: 179 GPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSII 221 >2CGA-A nrPDB Length = 245 Score = 150 bits (380), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 86/235 (36%), Positives = 129/235 (54%), Gaps = 13/235 (5%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHLGSDT-- 84 +I++G GS PWQV+L H CGG L+NE WV+TAAHC + V + + Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 73 Query: 85 -LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 + Q++K +K F++ Y++ T ND+ L+KL++ A S V V LPS + G Sbjct: 74 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 133 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 TTC +GWG T + P L + L+S +C K + ++++M+CAG S ++C Sbjct: 134 TTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGA--SGVSSC 191 Query: 202 NGDSGGPLVCRG----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPLVC+ TL G+VSWG+ C + PGVY +V W+ T+ + Sbjct: 192 MGDSGGPLVCKKNGAWTLVGIVSWGSSTC-STSTPGVYARVTALVNWVQQTLAAN 245 >1EUF-A nrPDB Length = 227 Score = 150 bits (378), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 90/236 (38%), Positives = 128/236 (54%), Gaps = 21/236 (8%) Query: 30 IIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ LL SG CGG LV E +VLTAAHC + V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP--PGT 142 +R Q I + HP Y+ +T ND+ML+KL +A ++ V + LP PG Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPGM 120 Query: 143 TCTVSGWGTTTSPDVTFPS--DLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNA 200 C+V+GWG V PS L VD+++ S + C +K+ + + +CAG P +KN+ Sbjct: 121 MCSVAGWGRL---GVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNS 177 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPND---PGVYTQVCKFTKWINDTMKKHR 253 +GDSGGPLVC G QG+VS+G ND P VYT++ F WI+ TM++++ Sbjct: 178 FSGDSGGPLVCNGVAQGIVSYGR------NDGTTPDVYTRISSFLSWIHSTMRRYK 227 >4GSO-A nrPDB Length = 232 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 77/219 (35%), Positives = 116/219 (52%), Gaps = 4/219 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLG--SDTLGD 87 ++ G C HP+ +A L + CG L+N+ WV+TAAHC + + LG S + + Sbjct: 1 VLGGDECDINEHPF-LAFLYSHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Q + F P + ++ D+ML+KL+ S + + LPS G+ C + Sbjct: 60 EDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSVGSVCRI 119 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 GWG+ T P+ T+P C ++ L+ + C Y L + LCAG+ + K+ C GDSG Sbjct: 120 MGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDTCVGDSG 179 Query: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 GPL+C G QG+VS+G CGQ PG+YT V +T WI Sbjct: 180 GPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWI 218 >4Q7Y-A nrPDB Length = 250 Score = 148 bits (373), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 90/232 (38%), Positives = 118/232 (50%), Gaps = 11/232 (4%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 II G S P+ ++ G Q HCGG L+ RWV++AAHC + V LG+ L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 86 --GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-CEPP-- 140 + Q HP Y TH ND+ L++LN A L V +RLP R PP Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS-KKN 199 GT C V+GWG + + P LM V+++ P C +K L +MLC DS ++ Sbjct: 121 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 179 Query: 200 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 C+ DSGGPLVCR GLVS+ CG P P VYTQV F WI D +++ Sbjct: 180 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 231 >3S69-A nrPDB Length = 234 Score = 147 bits (370), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 84/224 (37%), Positives = 115/224 (51%), Gaps = 4/224 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLG--SDTLGD 87 +I G C H VA + C G L+NE WVLTAAHC + + LG S + + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 88 RRAQRIKASKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Q + F P ++ D+ML+KL+S+ S + + LPS G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSVGSVCHI 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL-ENSMLCAGIPDSKKNACNGDS 205 GWG+ T VT+P C + L+ C Y +LL E LCAGI + K+ C GDS Sbjct: 121 MGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKDTCGGDS 180 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GGPL+C G QG+VS+G PCGQ PGVYT+V + WI + Sbjct: 181 GGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSII 224 >1OP0-A nrPDB Length = 234 Score = 146 bits (368), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 82/220 (37%), Positives = 114/220 (51%), Gaps = 4/220 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLG--SDTLGD 87 +I G C H + VA + CGG L+N WV+TAAHC ++ + LG S + + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 88 RRAQRIKASKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Q + F P + ++ D+ML+KL+ S + + LPS G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSVGSVCRI 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL-ENSMLCAGIPDSKKNACNGDS 205 GWG+ T TFP C ++ L+ C Y +LL E LCAGI K+ C GDS Sbjct: 121 MGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKDTCGGDS 180 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 GGPL+C G QG+VS+G PCGQ PG+YT V +T WI Sbjct: 181 GGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWI 220 >1NN6-A nrPDB Length = 228 Score = 146 bits (368), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 86/232 (37%), Positives = 124/232 (53%), Gaps = 17/232 (7%) Query: 29 KIIDGAPCARGSHPW----QVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 84 +II G C S P+ ++ +G CGG L+ +VLTAAHC TV LG+ Sbjct: 2 EIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHN 61 Query: 85 LGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PP 140 + + Q+++ K FRHP Y+T T +D+ML+KL +A L+ V + PS+ PP Sbjct: 62 ITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVPP 121 Query: 141 GTTCTVSGWGTTTSPDVTFPSD--LMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKK 198 G C V+GWG T V P L V ++L+ PQ C+ ++D N LC G P K Sbjct: 122 GRMCRVAGWGRT---GVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQLCVGNPRKTK 177 Query: 199 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +A GDSGGPL+C G QG+VS+G P V+T++ + WIN ++ Sbjct: 178 SAFKGDSGGPLLCAGVAQGIVSYGR---SDAKPPAVFTRISHYRPWINQILQ 226 >1BQY-A nrPDB Length = 234 Score = 145 bits (366), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 79/228 (34%), Positives = 115/228 (50%), Gaps = 4/228 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLG--SDTLGD 87 + G C H V L + N CGG L+N+ WV+TAAHC N + + G S + + Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 88 RRAQRIKASKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Q + F P V+ D+ML+KL+S S + + LPS G+ C + Sbjct: 61 EDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSVCRI 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYK-DLLENSMLCAGIPDSKKNACNGDS 205 GWG T +P C ++ ++ C Y + N+ LCAGI ++ C+ DS Sbjct: 121 MGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDTCHFDS 180 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GGPL+C G QG+VSWG PCGQP +PGVYT+V + WI + ++ Sbjct: 181 GGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGNK 228 >4E7N-A nrPDB Length = 238 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 81/228 (35%), Positives = 116/228 (50%), Gaps = 8/228 (3%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ--LHCGGVLVNERWVLTAAHCKMNEYTVHLG--SDTL 85 II G C H + VAL + L CGG L+N+ WVLTAAHC + + LG S + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 86 GDRRAQ-RIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + Q R+ K F + D+ML++L+S + S + LPS G+ C Sbjct: 61 PNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSVGSVC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL---LENSMLCAGIPDSKKNAC 201 + GWG + + T+P CV++ L+ + C Y + + LCAGI + K+ C Sbjct: 121 RIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTC 180 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GDSGGPL+C G QG+ SWG PC QP+ P YT+V WI + + Sbjct: 181 KGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENII 228 >3S9B-A nrPDB Length = 234 Score = 138 bits (348), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 81/233 (34%), Positives = 118/233 (50%), Gaps = 14/233 (6%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD 87 ++ G C HP+ VAL + + +HC G L+N WVLTAAHC + LG + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 88 RRAQ---RIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 R R+ K F D+ML++L S+ + V LPSR G+ C Sbjct: 61 RNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGVGSRC 120 Query: 145 TVSGWG---TTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPDSKKNA 200 + GWG TTT PDV C ++ ++ + C +Y + +S LCAGI ++ Sbjct: 121 RIMGWGKISTTTYPDVPH-----CTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDT 175 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 C+GDSGGPL+C G + G+V+ G+ PCGQ P VYT+V + WI + +R Sbjct: 176 CHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGNR 228 >5XRF-A nrPDB Length = 242 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 73/226 (32%), Positives = 111/226 (49%), Gaps = 6/226 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGN--QLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86 +I G C H + A + C G L++E WVL AAHC ++LG Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 87 --DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 D +R + + D++L+KLN S+ + + LPS G+ C Sbjct: 67 QFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPPSIGSVC 126 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPDSKKNACNG 203 V GWG +S P C ++ L++ +C Y D+ E + +LCAG+ + + CN Sbjct: 127 RVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGGIDTCNQ 186 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 DSGGPL+C G QG+V +G +PC QPN PG+YT+V + WI + + Sbjct: 187 DSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >1FI8-A nrPDB Length = 228 Score = 135 bits (339), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 86/232 (37%), Positives = 122/232 (52%), Gaps = 15/232 (6%) Query: 30 IIDGAPCARGSHPWQVAL-----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 84 II G S P+ L SG++ CGG L+ E +VLTAAHC ++ V LG+ Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSK-KCGGFLIREDFVLTAAHCSGSKIQVTLGAHN 59 Query: 85 LGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC--EPP 140 + ++ Q I K HP Y+++T ND+ML+KL S+A+ SS VK + LP R P Sbjct: 60 IKEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKP 119 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPDSKKN 199 G C V+GWG P + L V++ + Q C K+ + + +CAG P K+ Sbjct: 120 GDVCYVAGWG-KLGPMGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRA 178 Query: 200 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 + GDSGGPLVC+ G+VS+G + P +T+V F WI TMKK Sbjct: 179 SFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKK 227 >3F6U-H nrPDB Length = 240 Score = 134 bits (337), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 88/242 (36%), Positives = 129/242 (53%), Gaps = 24/242 (9%) Query: 30 IIDGAPCARGSHPWQVALL-SGNQLHCGGVLVNERWVLTAAHC--KMNEYTVHLGSDTLG 86 +IDG RG PWQV LL S +L CG VL++ WVLTAAHC + + V LG L Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDL- 59 Query: 87 DRRAQR----IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS------R 136 RR ++ + + F HP YS T ND+ L+ L A LS + + LP Sbjct: 60 -RRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERE 118 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSD----LMCVDVKLISPQDCTKVYKDLLENSMLCAG 192 G V+GWG +S + + L + + ++ +C++V +++ +MLCAG Sbjct: 119 LNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAG 178 Query: 193 IPDSKKNACNGDSGGPLVC--RGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 I +++AC GDSGGP+V GT L GLVSWG CG ++ GVYT+V ++ WI+ Sbjct: 179 ILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGE-GCGLLHNYGVYTKVSRYLDWIHGH 237 Query: 249 MK 250 ++ Sbjct: 238 IR 239 >1SC8-U nrPDB Length = 262 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 89/249 (35%), Positives = 125/249 (50%), Gaps = 27/249 (10%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQ-----LHCGGVLVNERWVLTAAHC-----KMNEYTV 78 KII G + PW A+ ++ CGG L++ WV++A HC K +Y V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 79 HLGSDTLGD--RRAQRIKASKSFRHPGYSTQT--HVNDLMLVKLNSQ----ARLSSMVKK 130 +LG L + + + H YS T H ND+ L+K+ S+ A+ S ++ Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 131 VRLPSRCEPP--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLEN 186 + LPS P GT+C ++G+G S D +P L VKLIS ++C + Y + Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTT 194 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242 MLCA P K ++C GDSGGPLVC R TL G+VSWG C + PGVYT+V F Sbjct: 195 KMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGR-GCALKDKPGVYTRVSHFL 253 Query: 243 KWINDTMKK 251 WI K+ Sbjct: 254 PWIRSHTKE 262 >3DFJ-A nrPDB Length = 263 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 87/246 (35%), Positives = 122/246 (49%), Gaps = 27/246 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE-----YTVHLGSDT 84 I G+ G PWQV++ CGG LV+E+WVL+AAHC +E Y V LG+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 LGDRRAQRIKAS---KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS--RCEP 139 L D ++ K S HP Y + D+ L++L+ S ++ + LP+ P Sbjct: 61 L-DSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFP 119 Query: 140 PGTTCTVSGWGTTTSPDVTF--PSDLMCVDVKLISPQDCTKVYK--------DLLENSML 189 G CTV+GWG +P V+ P L ++V LIS + C +Y ++ M+ Sbjct: 120 NGLHCTVTGWG-HVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMV 178 Query: 190 CAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 CAG + K+AC GDSGGPL C L G+VSWG CG N PGVYT + WI Sbjct: 179 CAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGD-ACGARNRPGVYTLASSYASWI 237 Query: 246 NDTMKK 251 + + Sbjct: 238 QSKVTE 243 >3E0N-B nrPDB Length = 271 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 87/246 (35%), Positives = 122/246 (49%), Gaps = 27/246 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE-----YTVHLGSDT 84 I G+ G PWQV++ CGG LV+E+WVL+AAHC +E Y V LG+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 LGDRRAQRIKAS---KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS--RCEP 139 L D ++ K S HP Y + D+ L++L+ S ++ + LP+ P Sbjct: 61 L-DSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFP 119 Query: 140 PGTTCTVSGWGTTTSPDVTF--PSDLMCVDVKLISPQDCTKVYK--------DLLENSML 189 G CTV+GWG +P V+ P L ++V LIS + C +Y ++ M+ Sbjct: 120 NGLHCTVTGWG-HVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMV 178 Query: 190 CAGIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 CAG + K+AC GDSGGPL C L G+VSWG CG N PGVYT + WI Sbjct: 179 CAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWI 237 Query: 246 NDTMKK 251 + + Sbjct: 238 QSKVTE 243 >3G01-A nrPDB Length = 227 Score = 131 bits (330), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 82/230 (35%), Positives = 116/230 (50%), Gaps = 13/230 (5%) Query: 30 IIDGAPCARGSHPW----QVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 85 II G + S P+ + + G ++ CGG LV +++VLTAAHCK TV LG+ + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 86 GDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 + Q I +K+ HP Y+ ND+ML+KL A+ + V+ + LP R PG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPDSKKNA 200 C V+GWG T PD FP L V + + Q C ++ + +C G K + Sbjct: 121 DECYVAGWGKVT-PDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGAS 179 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 GDSGGPLVC+ G+VS+G P V+T+V F WI TMK Sbjct: 180 FRGDSGGPLVCKRAAAGIVSYGQTDGSAPQ---VFTRVLSFVSWIKKTMK 226 >1MZD-A nrPDB Length = 240 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 85/235 (36%), Positives = 126/235 (53%), Gaps = 16/235 (6%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSD 83 +II G + S P+ ++ G CGGVL++ +WVLTAAHC K TV LG+ Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 84 TLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-PP 140 +L A Q ++ K ++ ND+MLVKL + A+L+ VK + + S+ Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 121 Query: 141 GTTCTVSGWGTTTSPDVTFPSD-LMCVDVKLISPQDC-TKVYKD---LLENSMLCAGIPD 195 GT C V+GWG T PD PSD L V V ++S + C ++ Y + + M+CAG Sbjct: 122 GTKCKVTGWGAT-DPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAK 180 Query: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVC-KFTKWINDTM 249 +K++C GD+GGPL+C+G +VS G CG PG+YT + K+ WI + Sbjct: 181 GQKDSCKGDAGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >4XDE-A nrPDB Length = 257 Score = 127 bits (319), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 88/242 (36%), Positives = 120/242 (49%), Gaps = 25/242 (10%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88 ++ G RG+HP+ AL G+ C G L+ WVLTAAHC + + LG Sbjct: 2 SVVGGLVALRGAHPYIAALYWGHSF-CAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQE 60 Query: 89 RAQ------RIKASKSFR-HPGYSTQTHVNDLMLVKLN-----SQARLSSMVKKVRLPSR 136 R + A +S+R H +S ++ +DL L++L S A LS V+ V LPS Sbjct: 61 RRNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSG 120 Query: 137 CEPPGTT--CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAG 192 P T C V+GWG + S L V +S + C+ V+ + MLCAG Sbjct: 121 AARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAG 180 Query: 193 IPDSKKNACNGDSGGPLVC-------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 + +AC GDSGGPLVC R TLQG++SWG+ CG N PGVYT V + WI Sbjct: 181 FLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVYTDVAYYLAWI 239 Query: 246 ND 247 + Sbjct: 240 RE 241 >3RP2-A nrPDB Length = 224 Score = 127 bits (319), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 80/228 (35%), Positives = 121/228 (53%), Gaps = 13/228 (5%) Query: 30 IIDGAPCARGSHPWQVAL----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 85 II G S P+ L G ++ CGG L++ ++VLTAAHCK E TV LG+ + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 86 GDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 R + Q+IK K H Y++ +++D+ML+KL + L+ V V LPS + PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 C +GWG T D T L V+++++ + C Y+ +C G P + + A Sbjct: 121 AMCWAAGWGKTGVRDPT-SYTLREVELRIMDEKACVD-YRYYEYKFQVCVGSPTTLRAAF 178 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GDSGGPL+C G G+VS+G P +P P ++T+V + WIN + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYG-HPDAKP--PAIFTRVSTYVPWINAVI 223 >5TJX-A nrPDB Length = 263 Score = 126 bits (316), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/236 (33%), Positives = 122/236 (51%), Gaps = 23/236 (9%) Query: 29 KIIDGAPCARGSHPWQVAL---LSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHL 80 +I+ G + G PWQV+L L+ + CGG L+ +WVLTAAHC + + ++ Sbjct: 15 RIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 74 Query: 81 G----SDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 G SD D +IK + H Y +D+ L+KL + + K + LPS+ Sbjct: 75 GILELSDITKDTPFSQIK--EIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSK 132 Query: 137 CEPPG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGI 193 + T C V+GWG + + L V++ L++ ++C K Y+D + M+CAG Sbjct: 133 GDTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 191 Query: 194 PDSKKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 + K+AC GDSGGPLVC+ L G+ SWG C + PGVYT+V ++ WI Sbjct: 192 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 246 >1BDA-A nrPDB Length = 265 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 84/243 (34%), Positives = 120/243 (49%), Gaps = 32/243 (13%) Query: 39 GSHPWQVALLS------GNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG------ 86 SHPWQ A+ + G + CGG+L++ W+L+AAHC + H + LG Sbjct: 23 ASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVV 82 Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQ----ARLSSMVKKVRLP--SRCEP 139 Q+ + K H + T+ ND+ L++L S A+ SS+V+ V LP P Sbjct: 83 PGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLP 142 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY--KDLLENSMLCAGIPDSK 197 T C +SG+G + + L V+L CT + + ++MLCAG S Sbjct: 143 DWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSG 202 Query: 198 ------KNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 +AC GDSGGPLVC R TL G++SWG CGQ + PGVYT+V + WI D Sbjct: 203 GPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWG-LGCGQKDVPGVYTKVTNYLDWIRD 261 Query: 248 TMK 250 M+ Sbjct: 262 NMR 264 >5LHN-A nrPDB Length = 247 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 123/247 (49%), Gaps = 28/247 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ------LHCGGVLVNERWVLTAAHC-----KMNEYTV 78 I+ G + PW A+ N+ CGG L++ WV +AAHC K Y V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 79 HLGS--DTLGDRRAQRIKASKSFRHPGYSTQT--HVNDLMLVKLNSQ----ARLSSMVKK 130 +LG ++ + + + + H Y + + ND+ L+K+ + A+ S ++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 131 VRLPSRC--EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLEN 186 + LP R P G+ C ++G+G + D +P +L VKL+S + C + Y + Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242 MLCA P+ K ++C GDSGGPL+C R TL G+VSWG C + N PGVYT+V F Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGR-GCAEKNKPGVYTRVSHFL 239 Query: 243 KWINDTM 249 WI + Sbjct: 240 DWIQSHI 246 >2PKA-B nrPDB Length = 152 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 59/148 (39%), Positives = 89/148 (60%), Gaps = 2/148 (1%) Query: 107 QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTS--PDVTFPSDLM 164 + + +DLML++L S A+++ VK + LP++ G+TC SGWG+ D FP ++ Sbjct: 4 KDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEIQ 63 Query: 165 CVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTF 224 CV + L+ C + D + SMLCAG K+ C GDSGGPL+C G QG+ SWG Sbjct: 64 CVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGHT 123 Query: 225 PCGQPNDPGVYTQVCKFTKWINDTMKKH 252 PCG N P +YT++ + WI+DT+ ++ Sbjct: 124 PCGSANKPSIYTKLIFYLDWIDDTITEN 151 >1IAU-A nrPDB Length = 227 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 81/231 (35%), Positives = 121/231 (52%), Gaps = 12/231 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQL---HCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ L+ +Q CGG L+ + +VLTAAHC + V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 142 ++ Q I + HP Y+ + ND+ML++L +A+ + V+ +RLPS PG Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM-LCAGIPDSKKNAC 201 TC+V+GWG T +P L V + + + C + ++++ LC G P+ KK + Sbjct: 121 TCSVAGWGQT-APLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPLVC QG+VS+G G P P T+V F WI TMK++ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGRN-NGMP--PRACTKVSSFVHWIKKTMKRY 227 >3T2N-A nrPDB Length = 372 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 85/249 (34%), Positives = 119/249 (47%), Gaps = 26/249 (10%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC------KMNEYTVHLG 81 D+I+ G + G PWQV+L CGG L++ WVLTAAHC ++ + V G Sbjct: 116 DRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAG 175 Query: 82 SDTLGDRRAQRIKASKSFRHPGY------STQTHVNDLMLVKLNSQARLSSMVKKVRLPS 135 + ++ H GY +++ + ND+ LV L+S L+ ++ V LP+ Sbjct: 176 AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPA 235 Query: 136 RCEP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKDLLENSMLCA 191 + G CTV+GWG T L V +IS C Y + ++ M CA Sbjct: 236 AGQALVDGKICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCA 294 Query: 192 GIPDSKKNACNGDSGGPLVC--------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTK 243 G P+ +AC GDSGGP VC R L G+VSWGT C PGVYT+V F + Sbjct: 295 GYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDFRE 353 Query: 244 WINDTMKKH 252 WI +K H Sbjct: 354 WIFQAIKTH 362 >2RDL-A nrPDB Length = 226 Score = 125 bits (313), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 120/232 (51%), Gaps = 15/232 (6%) Query: 30 IIDGAPCARGSHPWQVAL---LSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHLGSDT- 84 II G C + P+ L N L C G L+ +V+TAAHC TV LG+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 85 -LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 + + Q+++ K F HP Y + +ND+ML+KL +A L+ V + + ++ PPG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSD-LMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNA 200 C GWG T + PSD L V ++++ PQ C K ++D + LC G P +N Sbjct: 121 RVCRAVGWGRTNVNEP--PSDTLQEVKMRILDPQAC-KHFEDFHQEPQLCVGNPKKIRNV 177 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPL+C G QG+ S+ +P P V+T++ + WIN ++++ Sbjct: 178 YKGDSGGPLLCAGIAQGIASY-VLRNAKP--PSVFTRISHYRPWINKILREN 226 >4MPW-A nrPDB Length = 245 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 86/247 (34%), Positives = 123/247 (49%), Gaps = 29/247 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQL---HCGGVLVNERWVLTAAHC------KMNEYTVHL 80 I+ G R PWQV+L CGG L++ +WVLTAAHC + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 81 GSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 L + Q + S+ HP + T D+ L++L ++SS V V LP E Sbjct: 61 REQHLY-YQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETF 119 Query: 139 PPGTTCTVSGWGTTTSPD-VTFPSDLMCVDVKLISPQDCTKVYK---------DLLENSM 188 PPG C V+GWG + + + P L V V ++ C Y ++ + M Sbjct: 120 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 179 Query: 189 LCAGIPDSKKNACNGDSGGPLVCR--GTL--QGLVSWGTFPCGQPNDPGVYTQVCKFTKW 244 LCAG ++++++C GDSGGPLVC+ GT G+VSWG C QPN PG+YT+V + W Sbjct: 180 LCAG--NTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEG-CAQPNRPGIYTRVTYYLDW 236 Query: 245 INDTMKK 251 I+ + K Sbjct: 237 IHHYVPK 243 >4DGJ-A nrPDB Length = 235 Score = 123 bits (309), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 73/237 (30%), Positives = 125/237 (52%), Gaps = 20/237 (8%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC------KMNEYT----VH 79 I+ G+ G+ PW V L ++L CG LV+ W+++AAHC + +++T +H Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 80 LGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE- 138 + S+ + R+ + +P Y+ + ND+ ++ L + + ++ + LP + Sbjct: 61 MKSNLTSPQTVPRL-IDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQV 119 Query: 139 -PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDS 196 PPG C+++GWGT T L DV L+S + C + + + +M+CAG + Sbjct: 120 FPPGRNCSIAGWGTVVYQGTT-ADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEG 178 Query: 197 KKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 ++C GDSGGPL+C R L G+ S+G + C PN PGVY +V +FT+WI + Sbjct: 179 GIDSCQGDSGGPLMCQENNRWFLAGVTSFG-YECALPNRPGVYARVSRFTEWIQSFL 234 >2F91-A nrPDB Length = 237 Score = 123 bits (309), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 79/234 (33%), Positives = 113/234 (48%), Gaps = 20/234 (8%) Query: 30 IIDGAPCARGSHPWQVAL---LSGNQLH-CGGVLVNERWVLTAAHCKM-NEYTVHLGSD- 83 I+ G G P+Q++ G H CG + NE + +TA HC ++Y G Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 84 -------TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 ++ + Q I SK H + ND+ L+KL+ + V + LP + Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPD 195 V+GWGTT+ T P L V V L+S +DC Y D + +SM+CAG+P+ Sbjct: 121 GHTATGDVIVTGWGTTSEGGNT-PDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVPE 179 Query: 196 SKKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 K++C GDSGGPL T L G+VSWG + C +P PGVYT+V WI Sbjct: 180 GGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSYHVDWI 232 >1A5I-A nrPDB Length = 265 Score = 123 bits (308), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 85/241 (35%), Positives = 114/241 (47%), Gaps = 32/241 (13%) Query: 40 SHPWQVALL------SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG------- 86 SHPWQ A+ SG + CGG+L++ WVLTAAHC Y LG Sbjct: 24 SHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVLGRTYRVKP 83 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQ----ARLSSMVKKVRLPSRC--EPP 140 Q K K H + T+ ND+ L++L S A+ S V+ + LP P Sbjct: 84 GEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLPEANLQLPD 143 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAG------ 192 T C +SG+G S + L V+L C ++ + N+MLCAG Sbjct: 144 WTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLCAGDTRSGE 203 Query: 193 IPDSKKNACNGDSGGPLVCRG----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 I + +AC GDSGGPLVC TL G++SWG CG+ + PGVYT+V + WI D Sbjct: 204 IYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEKDVPGVYTKVTNYLGWIRDN 262 Query: 249 M 249 M Sbjct: 263 M 263 >1KYN-A nrPDB Length = 235 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 83/231 (35%), Positives = 116/231 (50%), Gaps = 12/231 (5%) Query: 30 IIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ L Q CGG LV E +VLTAAHC + V LG+ + Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 142 R Q I A ++ RHP Y+ +T ND+ML++L+ + R + V V LP E PGT Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGT 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACN 202 CTV+GWG + T L V +++ + C +++ +C G +K A Sbjct: 121 LCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFK 178 Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GDSGGPL+C G+VS+G G P P V+T+V F WI TM+ + Sbjct: 179 GDSGGPLLCNNVAHGIVSYGK-SSGVP--PEVFTRVSSFLPWIRTTMRSFK 226 >3TK9-A nrPDB Length = 226 Score = 122 bits (307), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 120/230 (52%), Gaps = 13/230 (5%) Query: 30 IIDGAPCARGSHPWQVA---LLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ L ++ CGG+LV + +VLTAAHC+ + V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 87 D--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 142 + R Q I + HP Y+ + N++ML++L +A+ ++ V+ +RLPS PG Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQ 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYK-DLLENSMLCAGIPDSKKNAC 201 C+V+GWG + T + L V + + C +++ + + +C G P + Sbjct: 121 LCSVAGWGYVSMS--TLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGF 178 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 GDSGGPLVC+ QG++S+G G P PGVY +V F WI TMK+ Sbjct: 179 KGDSGGPLVCKDVAQGILSYGN-KKGTP--PGVYIKVSHFLPWIKRTMKR 225 >6I44-A nrPDB Length = 627 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 79/236 (33%), Positives = 123/236 (52%), Gaps = 23/236 (9%) Query: 29 KIIDGAPCARGSHPWQVAL---LSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHL 80 +I+ G + G PWQV+L L+ + CGG L+ +WVLTAAHC + + ++ Sbjct: 379 RIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 438 Query: 81 G----SDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 G SD D +IK + H Y +D+ L+KL + + + K + LPS+ Sbjct: 439 GILQLSDITKDTPFSQIK--EIIIHQNYKVSEGNHDIALIKLQAPLQYTEFQKPICLPSK 496 Query: 137 CEPPG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGI 193 + T C V+GWG + + L V++ L++ ++C K Y+D + M+CAG Sbjct: 497 GDTSTIYTNCWVTGWGFSAEAG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 555 Query: 194 PDSKKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 + K+AC GD+GGPLVC+ L G+ SWG C + PGVYT+V ++ WI Sbjct: 556 KEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 610 >1P57-B nrPDB Length = 255 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 84/247 (34%), Positives = 117/247 (47%), Gaps = 26/247 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC------KMNEYTVHLGSD 83 I+ G + G PWQV+L CGG L++ WVLTAAHC ++ + V G+ Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 84 TLGDRRAQRIKASKSFRHPGY------STQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC 137 ++ H GY +++ + ND+ LV L+S L+ ++ V LP+ Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 138 EP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKDLLENSMLCAGI 193 + G CTV+GWG T L V +IS C Y + ++ M CAG Sbjct: 121 QALVDGKICTVTGWGNTQYYGQQ-AGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 179 Query: 194 PDSKKNACNGDSGGPLVC--------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 P+ +AC GDSGGP VC R L G+VSWGT C PGVYT+V F +WI Sbjct: 180 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKVSDFREWI 238 Query: 246 NDTMKKH 252 +K H Sbjct: 239 FQAIKTH 245 >5O32-I nrPDB Length = 244 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 82/237 (34%), Positives = 113/237 (47%), Gaps = 26/237 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 I+ G G PWQVA+ + + CGG+ + W+LTAAHC K + Y + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 86 GDRRAQRI---KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP--- 139 +RI + H Y+ T+ ND+ L+++ +P+ C P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA-CVPWSP 119 Query: 140 ----PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIP 194 P TC VSGWG + F L +VKLIS +C+K Y + E M CAG Sbjct: 120 YLFQPNDTCIVSGWGREKDNERVF--SLQWGEVKLIS--NCSKFYGNRFYEKEMECAGTY 175 Query: 195 DSKKNACNGDSGGPLVCRGT-----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 D +AC GDSGGPLVC + G+VSWG CG+P PGVYT+V + WI+ Sbjct: 176 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWIS 231 >2XRC-A nrPDB Length = 565 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 82/238 (34%), Positives = 114/238 (47%), Gaps = 26/238 (10%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDT 84 +I+ G G PWQVA+ + + CGG+ + W+LTAAHC K + Y + Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 85 LGDRRAQRI---KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP-- 139 +RI + H Y+ T+ ND+ L+++ +P+ C P Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPA-CVPWS 439 Query: 140 -----PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGI 193 P TC VSGWG + F L +VKLIS +C+K Y + E M CAG Sbjct: 440 PYLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLIS--NCSKFYGNRFYEKEMECAGT 495 Query: 194 PDSKKNACNGDSGGPLVCRGT-----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 D +AC GDSGGPLVC + G+VSWG CG+P PGVYT+V + WI+ Sbjct: 496 YDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGE-NCGKPEFPGVYTKVANYFDWIS 552 >1ORF-A nrPDB Length = 234 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 78/232 (33%), Positives = 121/232 (52%), Gaps = 12/232 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYT-VHLGSDTLGDR 88 II G S P+ V L + C G L+ + WVLTAAHC +N+ + V LG+ ++ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 89 R--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTTC 144 Q + K F +P Y T DL L++L +A+++ V + LP + + PGT C Sbjct: 61 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV----YKDLLENSMLCAGIPDSKKNA 200 V+GWG T + ++ L V++ +I + C + ++ +M+CAG +++ Sbjct: 121 QVAGWGRTHN-SASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 179 Query: 201 CNGDSGGPLVCRGTLQGLVSWG-TFPCGQPNDPGVYTQVC-KFTKWINDTMK 250 CNGDSG PL+C G +G+ S+G CG P PGVY + K WI T+K Sbjct: 180 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >1YC0-A nrPDB Length = 283 Score = 121 bits (304), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 123/245 (50%), Gaps = 22/245 (8%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88 +II G+ GSHPW A+ G+ C G LV+ WV++AAHC + S LG Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDSF-CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 89 RAQRI-KASKSF---RHPGYSTQTHVN----DLMLVKLNSQ----ARLSSMVKKVRLPS- 135 R +++F ++ Y+ + N DL+L++L + A S V+ + LP Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 153 Query: 136 -RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAG 192 P G C ++GWG + S L V L++ C+ +VY + +MLCAG Sbjct: 154 GSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAG 213 Query: 193 IPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 D K +AC GDSGGPL C L G++SWG CG+ + PGVYT+V + WIND Sbjct: 214 YFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDG-CGRLHKPGVYTRVANYVDWINDR 272 Query: 249 MKKHR 253 ++ R Sbjct: 273 IRPPR 277 >1LTO-A nrPDB Length = 245 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 87/247 (35%), Positives = 124/247 (50%), Gaps = 29/247 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQL---HCGGVLVNERWVLTAAHC------KMNEYTVHL 80 I+ G R PWQV+L ++ CGG L++ +WVLTAAHC + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 81 GSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 L + Q + S+ HP + D+ L++L +SS V V LP E Sbjct: 61 REQHLY-YQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASETF 119 Query: 139 PPGTTCTVSGWGTTTSPD-VTFPSDLMCVDVKLISPQDCTKVYK---------DLLENSM 188 PPG C V+GWG + + + P L V V ++ C Y ++ + M Sbjct: 120 PPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDDM 179 Query: 189 LCAGIPDSKKNACNGDSGGPLVCR--GT-LQ-GLVSWGTFPCGQPNDPGVYTQVCKFTKW 244 LCAG +S++++C GDSGGPLVC+ GT LQ G+VSW C QPN PG+YT+V + W Sbjct: 180 LCAG--NSQRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEG-CAQPNRPGIYTRVTYYLDW 236 Query: 245 INDTMKK 251 I+ + K Sbjct: 237 IHHYVPK 243 >2R0L-A nrPDB Length = 248 Score = 120 bits (302), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 84/244 (34%), Positives = 122/244 (50%), Gaps = 22/244 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 II G+ GSHPW A+ G+ C G LV+ WV++AAHC + S LG Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDSF-CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 90 AQRI-KASKSF---RHPGYSTQTHVN----DLMLVKLNSQ----ARLSSMVKKVRLPS-- 135 R +++F ++ Y+ + N DL+L++L + A S V+ + LP Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAGI 193 P G C ++GWG + S L V L++ C+ +VY + +MLCAG Sbjct: 120 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGY 179 Query: 194 PDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 D K +AC GDSGGPL C L G++SWG CG+ + PGVYT+V + WIND + Sbjct: 180 FDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVANYVDWINDRI 238 Query: 250 KKHR 253 + R Sbjct: 239 RPPR 242 >5GVT-A nrPDB Length = 250 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 81/235 (34%), Positives = 120/235 (51%), Gaps = 23/235 (9%) Query: 30 IIDGAPCARGSHPWQVALLSG--NQLH-CGGVLVNERWVLTAAHC-----KMNEYTVHLG 81 I+ G + G PWQV+L +Q H CGG ++ +WVLTAAHC + + ++ G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 82 ----SDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC 137 S+ + + RIK + H Y D+ L+KL + + K + LPS+ Sbjct: 61 ILSLSEITKETPSSRIK--ELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKA 118 Query: 138 EPPG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN-SMLCAGIP 194 + T C V+GWG T T + L + L+ ++C K Y+D + N M+CAG Sbjct: 119 DTNTIYTNCWVTGWGYTKEQGET-QNILQKATIPLVPNEECQKKYRDYVINKQMICAGYK 177 Query: 195 DSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 + +AC GDSGGPLVC R L G+ SWG C + + PGVYT+V ++ WI Sbjct: 178 EGGTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKVSEYMDWI 231 >3W94-A nrPDB Length = 235 Score = 118 bits (295), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 73/237 (30%), Positives = 116/237 (48%), Gaps = 18/237 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC------KMNEYTVHLGSD 83 ++ G +G+ PW V+L + CG L+ W+LTAAHC + ++ LG Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 84 TLGDRRAQRIKASKSFR---HPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 +Q ++ + R + Y+ +T D+ ++ L + V V L S + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSK 197 P G C ++GWG + P L +V L+ +C ++ + +SMLCAG P+ Sbjct: 121 PAGRRCFIAGWGRDAEGG-SLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGG 179 Query: 198 KNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 ++C GDSGGPL+C R TL G+ S+G CG+P PG Y +V FT WI +T + Sbjct: 180 VDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTSWIAETRR 235 >1EKB-B nrPDB Length = 235 Score = 116 bits (291), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 72/237 (30%), Positives = 118/237 (49%), Gaps = 20/237 (8%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYT----------VH 79 I+ G+ G+ PW VAL +Q CG LV+ W+++AAHC +H Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 80 LGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE- 138 + S+ + R+ + +P Y+ + ND+ ++ L + + ++ + LP + Sbjct: 61 MASNLTSPQIETRL-IDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQV 119 Query: 139 -PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDS 196 PPG C+++GWG T L DV L+S + C + + + +M+CAG Sbjct: 120 FPPGRICSIAGWGALIYQGST-ADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAG 178 Query: 197 KKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 ++C GDSGGPL+C R L G+ S+G + C PN PGVY +V +FT+WI + Sbjct: 179 GVDSCQGDSGGPLMCQENNRWLLAGVTSFG-YQCALPNRPGVYARVPRFTEWIQSFL 234 >6AOD-C nrPDB Length = 245 Score = 116 bits (291), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 77/233 (33%), Positives = 112/233 (48%), Gaps = 19/233 (8%) Query: 30 IIDGAPCARGSHPWQVAL--LSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 I+ G RG PWQV L S Q H CGG ++ +W+LTAAHC + + G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 87 DRRAQRIKASKSFR-------HPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139 + IK SF H Y D+ L+KL + + + + + LPS+ + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 140 P--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYK-DLLENSMLCAGIPDS 196 T C V+GWG D + L + L++ ++C K Y+ + + M+CAG + Sbjct: 121 NVIYTDCWVTGWGYRKLRD-KIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 197 KKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 K+AC GD+GGPL C+ L G+ SWG C Q PGVYT V ++ WI Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 231 >5UGG-A nrPDB Length = 251 Score = 115 bits (288), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 84/242 (34%), Positives = 126/242 (52%), Gaps = 29/242 (11%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHC-----KMNEYTVHLGS 82 +++ G S PWQV+L + +H CGG L++ WVLTAAHC + + Y V LG+ Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 83 --DTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS--RCE 138 + + Q I+ S+ F P D+ L+KL+S A ++ V LPS Sbjct: 81 HQEVNLEPHVQEIEVSRLFLEPTR------KDIALLKLSSPAVITDKVIPACLPSPNYVV 134 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMC-VDVKLISPQDCTKVYKDL---LENSMLCAGIP 194 T C ++GWG T TF + L+ + +I + C + Y+ L ++++ LCAG Sbjct: 135 ADRTECFITGWGETQG---TFGAGLLKEAQLPVIENKVCNR-YEFLNGRVQSTELCAGHL 190 Query: 195 DSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 ++C GDSGGPLVC + LQG+ SWG C +PN PGVY +V +F WI M+ Sbjct: 191 AGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRFVTWIEGVMR 249 Query: 251 KH 252 + Sbjct: 250 NN 251 >1PQ7-A nrPDB Length = 224 Score = 114 bits (286), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 79/227 (34%), Positives = 114/227 (50%), Gaps = 16/227 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 I+ G + G P+ V++ CGG L+N VLTAAHC + + + GS + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLS- 59 Query: 86 GDRRAQRIKAS-KSFR-HPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP--G 141 R + I +S S R HP YS NDL ++KL++ + RL + P G Sbjct: 60 --RTSGGITSSLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPVAG 115 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDSKKNA 200 ++ TV+GWG T+ + P +L+ V V ++S C Y + N M CAG+ K++ Sbjct: 116 SSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDS 175 Query: 201 CNGDSGGPLV-CRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 C GDSGGP+V TL G VSWG C +PN GVY V +I+ Sbjct: 176 CQGDSGGPIVDSSNTLIGAVSWGN-GCARPNYSGVYASVGALRSFID 221 >2F83-A nrPDB Length = 625 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 78/234 (33%), Positives = 111/234 (47%), Gaps = 19/234 (8%) Query: 29 KIIDGAPCARGSHPWQVAL--LSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 85 +I+ G RG PWQV L S Q H CGG ++ +W+LTAAHC + + Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 86 GDRRAQRIKASKSFR-------HPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE 138 G IK SF H Y D+ L+KL + + + + LPS+ + Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 139 PP--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYK-DLLENSMLCAGIPD 195 T C V+GWG D + L + L++ ++C K Y+ + + M+CAG + Sbjct: 507 RNVIYTDCWVTGWGYRKLRD-KIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYRE 565 Query: 196 SKKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 K+AC GDSGGPL C+ L G+ SWG C Q PGVYT V ++ WI Sbjct: 566 GGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 618 >1Q3X-A nrPDB Length = 328 Score = 114 bits (284), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 81/249 (32%), Positives = 117/249 (46%), Gaps = 33/249 (13%) Query: 27 GDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGS 82 G +I G G PWQV +L G G L+ + WVLTAAH K + + + Sbjct: 84 GGRIYGGQKAKPGDFPWQVLILGGTT--AAGALLYDNWVLTAAHAVYEQKHDASALDIRM 141 Query: 83 DTLGDRRAQRIKA--SKSFRHPGYSTQTHV-NDLMLVKLNSQARLSSMVKKVRLPS---- 135 TL +A F H GY+ ND+ L+KLN++ ++S + + LP Sbjct: 142 GTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAE 201 Query: 136 ---RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY------KDLLEN 186 R + GT SGWG T +LM VD+ ++ Q CT Y + + Sbjct: 202 SFMRTDDIGT---ASGWGLTQRG--FLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTA 256 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240 +MLCAG+ K++C GDSGG LV R + G+VSWG+ CG+ GVYT+V Sbjct: 257 NMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVIN 316 Query: 241 FTKWINDTM 249 + WI + + Sbjct: 317 YIPWIENII 325 >4Z6A-H nrPDB Length = 249 Score = 113 bits (283), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 82/239 (34%), Positives = 116/239 (48%), Gaps = 22/239 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC--KMNEY---TVHLGSDT 84 I+ G C +G PWQV LL CGG L+N WV++AAHC K+ + LG Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 85 L----GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP 140 L GD +++R+ ++ Y T +D+ L++L+ L+ V + LP R Sbjct: 61 LSEHDGDEQSRRV--AQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSE 118 Query: 141 GTTC-----TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195 T VSGWG T +LM ++V + QDC Y + M CAG D Sbjct: 119 RTLAFVRFSLVSGWGQLLDRGAT-ALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSD 177 Query: 196 SKKNACNGDSGGPLVC--RGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 K++C GDSGGP RGT L G+VSWG C GVYT+V ++ +W+ M+ Sbjct: 178 GSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQ-GCATVGHFGVYTRVSQYIEWLQKLMR 235 >4DJZ-B nrPDB Length = 251 Score = 113 bits (282), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 114/248 (45%), Gaps = 35/248 (14%) Query: 30 IIDGAPCARGSHPWQVALLS--GNQLHCGGVLVNERWVLTAAHC---------------- 71 I +G P +G+ PW +A+LS Q CGG L+ W++TAAHC Sbjct: 1 IFNGRPAQKGTTPW-IAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSD 59 Query: 72 --KMNEYTVHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSM 127 +++ + LG D Q + + HP Y T ND+ LV+L L++ Sbjct: 60 LLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAF 119 Query: 128 VKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY---KDLL 184 V + LP + G VSGWG FP LM +++ ++ C K Y K + Sbjct: 120 VMPICLPEGPQQEGAMVIVSGWGKQFLQ--RFPETLMEIEIPIVDHSTCQKAYAPLKKKV 177 Query: 185 ENSMLCAGIPDSKKNACNGDSGGPLVC----RGT--LQGLVSWGTFPCGQPNDPGVYTQV 238 M+CAG + K+AC GDSGGP+V RG L G VSWG CG+ + GVY+ + Sbjct: 178 TRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGKKDRYGVYSYI 236 Query: 239 CKFTKWIN 246 WI Sbjct: 237 HHNKDWIQ 244 >4IGD-A nrPDB Length = 406 Score = 113 bits (282), Expect = 9e-26, Method: Compositional matrix adjust. Identities = 80/248 (32%), Positives = 115/248 (46%), Gaps = 35/248 (14%) Query: 29 KIIDGAPCARGSHPWQVALLS--GNQLHCGGVLVNERWVLTAAHC--------------- 71 +I +G P +G+ PW +A+LS Q CGG L+ W++TAAHC Sbjct: 155 QIFNGRPAQKGTTPW-IAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDS 213 Query: 72 ---KMNEYTVHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS 126 +++ + LG D Q + + HP Y T ND+ LV+L L++ Sbjct: 214 DLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNA 273 Query: 127 MVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL--- 183 V + LP + G VSGWG FP LM +++ ++ C K Y L Sbjct: 274 FVMPICLPEGPQQEGAMVIVSGWGKQFLQ--RFPETLMEIEIPIVDHSTCQKAYAPLKKK 331 Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLVC----RGT--LQGLVSWGTFPCGQPNDPGVYTQ 237 + M+CAG + K+AC GDSGGP+V RG L G VSWG CG+ + GVY+ Sbjct: 332 VTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGKKDRYGVYSY 390 Query: 238 VCKFTKWI 245 + WI Sbjct: 391 IHHNKDWI 398 >2OQ5-A nrPDB Length = 232 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 78/233 (33%), Positives = 108/233 (46%), Gaps = 24/233 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--- 86 I+ G G PWQ +L CG L+N W+++AAHC + + G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 87 -----DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEP 139 R +RI + ++HP +H D+ L +L+S ++ V +V LP S Sbjct: 61 KPSKMKRGLRRIIVHEKYKHP-----SHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQ 115 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAGIPDSK 197 PG V+G+G + D + L V LI C + Y D + MLCAG + K Sbjct: 116 PGDVMFVTGFGALKN-DGYSQNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGK 174 Query: 198 KNACNGDSGGPLVCRGT-----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 +AC GDSGGPLV L G+VSWG C +PN PGVYT+V WI Sbjct: 175 TDACQGDSGGPLVSSDARDIWYLAGIVSWGD-ECAKPNKPGVYTRVTALRDWI 226 >1FDP-A nrPDB Length = 235 Score = 112 bits (281), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 73/232 (31%), Positives = 121/232 (52%), Gaps = 15/232 (6%) Query: 29 KIIDGAPCARGSHPWQVAL-LSGNQLHCGGVLVNERWVLTAAHCKMN----EYTVHLGSD 83 +I+ G + P+ ++ L+G L CGGVLV E+WVL+AAHC + + V LG+ Sbjct: 7 RILGGREAEAHARPYMASVQLNGAHL-CGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAH 65 Query: 84 TLGDRRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKV--RLPSRCEP 139 +L + ++ HP T +DL+L++L+ +A L V+ + + R Sbjct: 66 SLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVA 125 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLCAGIPDSK 197 PGT C V+GWG P L V + ++ C + + + ++CA ++ Sbjct: 126 PGTLCDVAGWGIVNHAG-RRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ESNR 182 Query: 198 KNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 +++C GDSGGPLVC G L+G+V+ G+ CG PG+YT+V + WI+ + Sbjct: 183 RDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVL 234 >1ZJK-A nrPDB Length = 403 Score = 112 bits (280), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 81/249 (32%), Positives = 118/249 (47%), Gaps = 33/249 (13%) Query: 27 GDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGS 82 G +I G G PWQV +L G G L+ + WVLTAAH K + + + Sbjct: 159 GGQIYGGQKAKPGDFPWQVLILGGTT--AAGALLYDNWVLTAAHAVYEQKHDASALDIRM 216 Query: 83 DTLGDRRAQRIKA--SKSFRHPGYSTQTHV-NDLMLVKLNSQARLSSMVKKVRLPS---- 135 TL +A F H GY+ ND+ L+KLN++ ++S + + LP Sbjct: 217 GTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAE 276 Query: 136 ---RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY------KDLLEN 186 R + GT SGWG T + +LM VD+ ++ Q CT Y + + Sbjct: 277 SFMRTDDIGT---ASGWGLTQRGFLA--RNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTA 331 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240 +MLCAG+ K++C GDSGG LV R + G+VSWG+ CG+ GVYT+V Sbjct: 332 NMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVIN 391 Query: 241 FTKWINDTM 249 + WI + + Sbjct: 392 YIPWIENII 400 >5FCR-A nrPDB Length = 234 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 75/231 (32%), Positives = 116/231 (50%), Gaps = 18/231 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSDT 84 I+ G A + P+ ++ CGG L++E+WVL+AAHC + V LG+ + Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 85 LGDRRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE---- 138 L + HPG + +DL+L KL+ A L V+ LP + E Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRP--LPLQYEDKEV 118 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT-KVYKD-LLENSMLCAGIPDS 196 PGT C V+GWG T P L + V +++ C + Y D ++ +M+CA + Sbjct: 119 EPGTLCDVAGWGVVTHAG-RRPDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESN 175 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 +++ C GDSG PLVC ++G+V+WG+ CG PGVYT+V + WI + Sbjct: 176 RRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 >4FXG-H nrPDB Length = 242 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 77/243 (31%), Positives = 113/243 (46%), Gaps = 27/243 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 I G G PWQV +L G G L+ + WVLTAAH K + + + TL Sbjct: 1 IYGGQKAKPGDFPWQVLILGGTT--AAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 86 GDRRAQRIKA--SKSFRHPGYSTQTHV-NDLMLVKLNSQARLSSMVKKVRLPSRCEPP-- 140 +A F H GY+ ND+ L+KLN++ ++S + + LP + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 141 --GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY------KDLLENSMLCAG 192 T SGWG T +LM VD+ ++ Q CT Y + + +MLCAG Sbjct: 119 RTDDIGTASGWGLTQRG--FLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAG 176 Query: 193 IPDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 + K++C GD+GG LV R + G+VSWG+ CG+ GVYT+V + WI Sbjct: 177 LESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIE 236 Query: 247 DTM 249 + + Sbjct: 237 NII 239 >1KIG-H nrPDB Length = 241 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 75/235 (31%), Positives = 111/235 (47%), Gaps = 16/235 (6%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHC--KMNEYTVHLGSDTLG 86 I+ G CA G PWQ L++ N+ CGG ++NE +VLTAAHC + +TV +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 87 DRRAQRI--KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + + + +H + +T+ D+ +++L + R V LP + T Sbjct: 61 QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLM 120 Query: 145 T-----VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 T VSG+G T S L ++V + C + +M CAG ++ Sbjct: 121 TQKTGIVSGFGRTHEKG-RLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPED 179 Query: 200 ACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 AC GDSGGP V R + G+VSWG C + GVYT+V F KWI+ MK Sbjct: 180 ACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKFGVYTKVSNFLKWIDKIMK 233 >4DUR-A nrPDB Length = 791 Score = 110 bits (276), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 85/246 (34%), Positives = 127/246 (51%), Gaps = 37/246 (15%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHC-----KMNEYTVHLGS 82 +++ G S PWQV+L + +H CGG L++ WVLTAAHC + + Y V LG+ Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 83 --DTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP 140 + + Q I+ S+ F P D+ L+KL+S A ++ V LPS P Sbjct: 621 HQEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLSSPAVITDKVIPACLPS----P 670 Query: 141 G------TTCTVSGWGTTTSPDVTFPSDLMC-VDVKLISPQDCTKVYKDL---LENSMLC 190 T C ++GWG T TF + L+ + +I + C + Y+ L ++++ LC Sbjct: 671 NYVVADRTECFITGWGETQG---TFGAGLLKEAQLPVIENKVCNR-YEFLNGRVQSTELC 726 Query: 191 AGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 AG ++C GDSGGPLVC + LQG+ SWG C +PN PGVY +V +F WI Sbjct: 727 AGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRFVTWIE 785 Query: 247 DTMKKH 252 M+ + Sbjct: 786 GVMRNN 791 >5XW8-A nrPDB Length = 133 Score = 110 bits (274), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 57/127 (44%), Positives = 76/127 (59%), Gaps = 3/127 (2%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG- 86 DKI+ G CA S P+QV+L SG+ CGG L+N +WV++AAHC + V LG + Sbjct: 7 DKIVGGYTCAANSIPYQVSLNSGSHF-CGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDV 65 Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 + Q I A+K HP ++ T ND+ML+KL+S A L+S V V LP C GT C Sbjct: 66 LEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECL 125 Query: 146 VSGWGTT 152 +SGWG T Sbjct: 126 ISGWGNT 132 >1MKW-K nrPDB Length = 308 Score = 109 bits (273), Expect = 9e-25, Method: Compositional matrix adjust. Identities = 82/258 (31%), Positives = 122/258 (47%), Gaps = 36/258 (13%) Query: 29 KIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHC----------KMNEY 76 +I++G G PWQV L S +L CG L+++RWVLTAAHC +++ Sbjct: 49 RIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDL 108 Query: 77 TVHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVR 132 V +G S T +R+ ++I K + HP Y+ + +++ D+ L+KL LS + V Sbjct: 109 LVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVC 168 Query: 133 LPSRCEP-----PGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182 LP + G V+GWG TTS PS L V++ L+ C + Sbjct: 169 LPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRI 228 Query: 183 LLENSMLCAGI---PDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPG 233 + ++M CAG + +AC GDSGGP V R G+VSWG C + G Sbjct: 229 RITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE-GCDRDGKYG 287 Query: 234 VYTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 288 FYTHVFRLKKWIQKVIDR 305 >3P8G-A nrPDB Length = 241 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 76/240 (31%), Positives = 112/240 (46%), Gaps = 23/240 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMN----------EYTV 78 ++ G G PWQV+L + Q H CG L++ W+++AAHC ++ ++T Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 79 HLGSDTLGDRRA---QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP- 134 LG R A Q + + HP ++ T D+ L++L A SSMV+ + LP Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 135 -SRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI 193 S P G V+GWG T T L ++++I C + + M+C G Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGG-TGALILQKGEIRVIQQTTCENLLPQQITPRMMCVGF 179 Query: 194 PDSKKNACNGDSGGPLVC-----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 ++C GDSGGPL R G+VSWG C Q N PGVYT++ F WI + Sbjct: 180 LSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD-GCAQRNKPGVYTRLPLFRDWIKEN 238 >3NXP-A nrPDB Length = 424 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 82/258 (31%), Positives = 122/258 (47%), Gaps = 36/258 (13%) Query: 29 KIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEY 76 +I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 165 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 224 Query: 77 TVHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVR 132 V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + V Sbjct: 225 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 284 Query: 133 LPSRCEP-----PGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182 LP R G V+GWG T + PS L V++ ++ C + Sbjct: 285 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 344 Query: 183 LLENSMLCAGI-PDSKK--NACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPG 233 + ++M CAG PD K +AC GDSGGP V + G+VSWG C + G Sbjct: 345 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRDGKYG 403 Query: 234 VYTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 404 FYTHVFRLKKWIQKVIDQ 421 >3K65-B nrPDB Length = 308 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 81/258 (31%), Positives = 122/258 (47%), Gaps = 36/258 (13%) Query: 29 KIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEY 76 +I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 49 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 108 Query: 77 TVHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVR 132 V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + V Sbjct: 109 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 168 Query: 133 LPSRCEP-----PGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182 LP R G V+GWG T + PS L V++ ++ C + Sbjct: 169 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 228 Query: 183 LLENSMLCAGI-PDSKK--NACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPG 233 + ++M CAG PD K +AC GD+GGP V + G+VSWG C + G Sbjct: 229 RITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGE-GCDRDGKYG 287 Query: 234 VYTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 288 FYTHVFRLKKWIQKVIDQ 305 >1ETT-H nrPDB Length = 259 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 82/257 (31%), Positives = 122/257 (47%), Gaps = 36/257 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHC----------KMNEYT 77 I++G G PWQV L S +L CG L+++RWVLTAAHC +++ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRL 133 V +G S T +R+ ++I K + HP Y+ + +++ D+ L+KL LS + V L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 134 P-----SRCEPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183 P ++ G V+GWG TTS PS L V++ L+ C + Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 184 LENSMLCAGI---PDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGV 234 + ++M CAG + +AC GDSGGP V R G+VSWG C + G Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE-GCDRDGKYGF 239 Query: 235 YTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 240 YTHVFRLKKWIQKVIDR 256 >2OCV-B nrPDB Length = 259 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 124/257 (48%), Gaps = 36/257 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G +G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 78 VHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRL 133 V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + V L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 134 PSR-----CEPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183 P + G V+GWG TT+ + PS L V++ ++ C + Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 184 LENSMLCAG--IPDSKK-NACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPGV 234 + ++M CAG + D+K+ +AC GDSGGP V + G+VSWG C + G Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRKGKYGF 239 Query: 235 YTQVCKFTKWINDTMKK 251 YT V + WI + + Sbjct: 240 YTHVFRLKAWIQKVIDQ 256 >1BRU-P nrPDB Length = 241 Score = 108 bits (269), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 83/247 (33%), Positives = 124/247 (50%), Gaps = 30/247 (12%) Query: 30 IIDGAPCARGSHPWQVALL---SGNQLH-CGGVLVNERWVLTAAHC--KMNEYTVHLGSD 83 ++ G S PWQV+L SG H CGG LV++ WVLTAAHC Y V LG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 84 TLGDRR--AQRIKASKSFRHPGYSTQ--THVNDLMLVKLNSQARLSSMVKKVRLPSRCE- 138 +L + +K SK H +++ ++ ND+ L+KL S L+ ++ LP+ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 139 -PPGTTCTVSGWG----TTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCA 191 P C V+GWG SPD+ L+ VD C+K + ++ +M+CA Sbjct: 121 LPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYA-----TCSKPGWWGSTVKTNMICA 175 Query: 192 GIPDSKKNACNGDSGGPLVCRGT-----LQGLVSWG-TFPCGQPNDPGVYTQVCKFTKWI 245 G D ++CNGDSGGPL C+G + G+VS+G + C + P V+T+V + WI Sbjct: 176 G-GDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWI 234 Query: 246 NDTMKKH 252 N + + Sbjct: 235 NSVIANN 241 >4NZQ-A nrPDB Length = 557 Score = 107 bits (268), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 82/258 (31%), Positives = 122/258 (47%), Gaps = 36/258 (13%) Query: 29 KIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEY 76 +I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 298 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 357 Query: 77 TVHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVR 132 V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + V Sbjct: 358 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVC 417 Query: 133 LPSRCEP-----PGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKD 182 LP R G V+GWG T + PS L V++ ++ C + Sbjct: 418 LPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRI 477 Query: 183 LLENSMLCAGI-PDSKK--NACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPG 233 + ++M CAG PD K +AC GDSGGP V + G+VSWG C + G Sbjct: 478 RITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRDGKYG 536 Query: 234 VYTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 537 FYTHVFRLKKWIQKVIDQ 554 >2OLG-A nrPDB Length = 278 Score = 106 bits (265), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 77/267 (28%), Positives = 122/267 (45%), Gaps = 42/267 (15%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALLSGN-----QLHCGGVLVNERWVLTAAHC----- 71 G + + DKI++G PW + N Q CGG L+N R+++TAAHC Sbjct: 15 GYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRV 74 Query: 72 ----------KMNEYTVHLGSDTLGDRRA------QRIKASKSFRHPGY--STQTHVNDL 113 ++ E+ D G R + ++ +HP Y ++ +D+ Sbjct: 75 LRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDI 134 Query: 114 MLVKLNSQARLSSMVKKVRLPSRCEP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLI 171 L++LN Q ++ ++ V LP E G TV GWG T + + + V V + Sbjct: 135 ALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETGQYSTIKQKLAVPV--V 192 Query: 172 SPQDCTKVYKDL---LENSMLCAGIPDSKKNACNGDSGGPLVCRGT-----LQGLVSWGT 223 + C K + + +S LCAG + K++C GDSGGPL+ L+GLVS+G Sbjct: 193 HAEQCAKTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGA 251 Query: 224 FPCGQPNDPGVYTQVCKFTKWINDTMK 250 CG PG+YT+V K+ WI ++ Sbjct: 252 -TCGTEGWPGIYTKVGKYRDWIEGNIR 277 >1AZZ-A nrPDB Length = 226 Score = 106 bits (265), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 71/222 (31%), Positives = 106/222 (47%), Gaps = 10/222 (4%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC--KMNEYTVHLGSDTLGD 87 I+ G S P Q AL + CGG L++ W+LTAAHC V LG+ + + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 88 RRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 A + I+++ H Y++ ND+ +++L L++ + V LPS GT T Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGVGTVVT 120 Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSK--KNACNG 203 +GWG + + L VDV ++S DC VY ++ + +C DS K CNG Sbjct: 121 PTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVYG-IVTDGNICI---DSTGGKGTCNG 176 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 DSGGPL G G+ S+G + P +T+V F WI Sbjct: 177 DSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWI 218 >1C5M-D nrPDB Length = 255 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 114/238 (47%), Gaps = 22/238 (9%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDR 88 I+ G C G PWQ L++ N+ CGG +++E ++LTAAHC Y +GDR Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCL---YQAKRFKVRVGDR 57 Query: 89 RAQRIKASKS-------FRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPG 141 ++ + ++ +H ++ +T+ D+ +++L + V LP R Sbjct: 58 NTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAES 117 Query: 142 TTCT-----VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 T T VSG+G T + L ++V + C ++ +M CAG Sbjct: 118 TLMTQKTGIVSGFGRTHEKGRQ-STRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTK 176 Query: 197 KKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +++AC GDSGGP V R + G+VSWG C + G+YT+V F KWI+ +MK Sbjct: 177 QEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKYGIYTKVTAFLKWIDRSMK 233 >1FIW-A nrPDB Length = 290 Score = 105 bits (261), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 112/245 (45%), Gaps = 30/245 (12%) Query: 30 IIDGAPCARGSHPWQVALL-----SGNQLH-CGGVLVNERWVLTAAHC-----KMNEYTV 78 II G A G+ PW V+L + + H CGG L+N +W+LTAAHC K+ ++ + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 HLGSDTLGDRRAQRIK-------ASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKV 131 G+ + + +K K H YS + ND+ L+K+ + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 132 RLPS-RCEPPGT--TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKDLLEN 186 LP R PP TC V+GWG L V LI C T+ Y + + Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPGVYTQVCK 240 + +CAG P+ K + C GDSGGPL+C+ + + G+ SWG C + PGVYT Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTWS 239 Query: 241 FTKWI 245 + WI Sbjct: 240 YLNWI 244 >1VR1-H nrPDB Length = 261 Score = 104 bits (260), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 80/261 (30%), Positives = 120/261 (45%), Gaps = 40/261 (15%) Query: 30 IIDGAPCARGSHPWQVALLS------GNQLHCGGVLVNERWVLTAAHCKM---------- 73 I++G+ G PWQV L + G + CG L+++RWVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 74 NEYTVHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVK 129 N+ V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 130 KVRLPSRCEP-----PGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKV 179 V LP R G V+GWG T + PS L V++ ++ C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 180 YKDLLENSMLCAGI-PDSKK--NACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPN 230 + + ++M CA PD K +AC GDSGGP V + G+VSWG C + Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRDG 239 Query: 231 DPGVYTQVCKFTKWINDTMKK 251 G YT V + KWI + + Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQ 260 >2XXL-A nrPDB Length = 408 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 83/262 (31%), Positives = 122/262 (46%), Gaps = 48/262 (18%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLH-----CGGVLVNERWVLTAAHC----KMNEYTVH 79 ++ +G S PW +ALL Q CGG +++ER++LTAAHC + + Y + Sbjct: 118 RVSNGYEVKLSSRPW-MALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEIR 176 Query: 80 LGS---DTLGDRRAQ-----------RIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLS 125 LG T D R Q + K H Y + ++D+ L+KLN Sbjct: 177 LGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPFQ 236 Query: 126 SMVKKVRLPSRCE-----PPGTTCTVSGWGTT---TSPDVTFPSDLMCVDVKLISPQDCT 177 +K + LP E +T V+GWGTT +S DV L+ +V L C+ Sbjct: 237 KHIKPICLPITDELKEKAEQISTYFVTGWGTTENGSSSDV-----LLQANVPLQPRSACS 291 Query: 178 KVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVC----------RGTLQGLVSWGTFPCG 227 + Y+ + S LC G D +++C GDSGGPL + G+VS G CG Sbjct: 292 QAYRRAVPLSQLCVGGGD-LQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCG 350 Query: 228 QPNDPGVYTQVCKFTKWINDTM 249 Q + PG+YT V ++ +WI DTM Sbjct: 351 QISLPGLYTNVGEYVQWITDTM 372 >1FIZ-A nrPDB Length = 263 Score = 103 bits (256), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 73/245 (29%), Positives = 112/245 (45%), Gaps = 30/245 (12%) Query: 30 IIDGAPCARGSHPW----QVALLSGNQLH--CGGVLVNERWVLTAAHC-----KMNEYTV 78 ++ G G+ PW Q+ + N+ + CGG+L+N WVLTAAHC K+ ++ + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 HLGSDTL--GDRRAQRIKASKSFR-----HPGYSTQTHVNDLMLVKLNSQARLSSMVKKV 131 G++ + G + + + F H Y + +ND+ L+K+ + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 132 RLPS-RCEPPGT--TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKDLLEN 186 LP + PP TC V+GWG L V LI + C T+ Y + + Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPGVYTQVCK 240 + +CAG P K + C GDSGGPL+CR + G+ SWG C + PGVYT Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGVG-CARAKRPGVYTSTWP 239 Query: 241 FTKWI 245 + WI Sbjct: 240 YLNWI 244 >1EQ9-A nrPDB Length = 222 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 71/228 (31%), Positives = 117/228 (51%), Gaps = 12/228 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSDT 84 I+ G G +P+QV+L CG +++ VLTAAHC +N VH+G++ Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP-PGTT 143 L + + + Y ND+ LV L + + + +V+ ++L + E Sbjct: 61 LSES-GDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLESNP 119 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG 203 CT++GWG+T T P+ L +++ ++ PQ + + + +S +C + + AC+G Sbjct: 120 CTLTGWGSTRLGGNT-PNALQEIEL-IVHPQKQCERDQWRVIDSHICT-LTKRGEGACHG 176 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 DSGGPLV G G+VS+G+ PC +P VYT+V F WIN +KK Sbjct: 177 DSGGPLVANGAQIGIVSFGS-PCAL-GEPDVYTRVSSFVSWINANLKK 222 >2ZKS-A nrPDB Length = 240 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/231 (32%), Positives = 112/231 (48%), Gaps = 16/231 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC---KMNEYTVHLGSDTLG 86 II G S P+ +L CGGVLV+ +WVLTAAHC +M + + LG TL Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTL- 59 Query: 87 DRRAQRIKASKSFRHPGYSTQTHV-NDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 D + +HP Y + NDL L++L+ + + S ++ + LPS+ + GT Sbjct: 60 DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGTR 119 Query: 144 CTVSGWGTTTS----PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 C+++GWG T V DL +D ++ + ++ + L SM+C + Sbjct: 120 CSMAGWGLTHQGGRLSRVLRELDLQVLDTRMC---NNSRFWNGSLSPSMVCLAADSKDQA 176 Query: 200 ACNGDSGGPLVC-RG-TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 C GDSGGPLVC +G L G++S+ + C P V T V + WI Sbjct: 177 PCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 227 >1AE5-A nrPDB Length = 225 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 70/232 (30%), Positives = 114/232 (49%), Gaps = 23/232 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE----YTVHLGSDTL 85 I+ G P+ ++ + + CGG L++ R+V+TAA C ++ TV LG+ L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 86 G--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEPPG 141 +R++++ + S GY Q ++NDLML++L+ +A L+S V + LP + G Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 142 TTCTVSGWGTTTSPD--VTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 T C V+GWG+ S FP + + T +D + +C G+ + Sbjct: 121 TRCQVAGWGSQRSGGRLSRFPRFV-----------NVTVTPEDQCRPNNVCTGVLTRRGG 169 Query: 200 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 CNGD G PLVC G G+ S+ PCG+ P +T+V F WI+ + Sbjct: 170 ICNGDGGTPLVCEGLAHGVASFSLGPCGR--GPDFFTRVALFRDWIDGVLNN 219 >1SI5-H nrPDB Length = 240 Score = 100 bits (250), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 70/235 (29%), Positives = 110/235 (46%), Gaps = 16/235 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 +++G P R + W V+L N+ CGG L+ E WVLTA C + +Y LG + Sbjct: 1 VVNGIP-TRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDV 59 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 R ++ K + Y + +DL+L+KL A L V + LP+ P T+ Sbjct: 60 HGRGDEKCKQVLNVSQLVYGPEG--SDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTS 117 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY--KDLLENSMLCAGIPDSKKNAC 201 C+V GWG T + + L + ++ + C++ + K L S +CAG C Sbjct: 118 CSVYGWGYTGL--INYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPC 175 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFP---CGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GD GGPLVC +V P C PN PG++ +V + KWI+ + ++ Sbjct: 176 EGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYK 230 >5TO3-B nrPDB Length = 409 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 81/257 (31%), Positives = 120/257 (46%), Gaps = 36/257 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRL 133 V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + V L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 134 PSRCEP-----PGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183 P R G V+GWG T + PS L V++ ++ C + Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 184 LENSMLCAGI-PDSKK--NACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPGV 234 + ++M CAG PD K +AC GDSGGP V + G+VS G C + G Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA-GCDRDGKYGF 239 Query: 235 YTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 240 YTHVFRLKKWIQKVIDQ 256 >1X7A-C nrPDB Length = 235 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 71/235 (30%), Positives = 111/235 (47%), Gaps = 16/235 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM--NEYTVHLGSDTLGD 87 I+ G G PWQV L CGG ++NE+WV+TAAHC + TV G + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 88 RR--AQRIKASKSFRHPGY--STQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP---- 139 QR ++ H Y + + +D+ L++L+ L+S V + + + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFL 120 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 + VSGWG + + + L + V L+ C + K + ++M CAG + K+ Sbjct: 121 KFGSGYVSGWGRVFNRGRS-ATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGKD 179 Query: 200 ACNGDSGGPLV--CRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +C GDSGGP V GT L G++SWG C G+YT+V ++ WI + K Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAVKGKYGIYTKVSRYVNWIKEKTK 233 >4LK4-A nrPDB Length = 357 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/234 (33%), Positives = 111/234 (47%), Gaps = 19/234 (8%) Query: 29 KIIDGAPCARGSHPWQVALL-----SGNQLHCGGVLVNERWVLTAAHC----KMNEYTVH 79 +II+G+ P VAL+ + CGG + R+VLTAAHC V Sbjct: 10 RIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAASVDVI 69 Query: 80 LGSDTLGDR-RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE 138 +G+ L + + +RI A K +RH YS +ND+ +V+L + L ++ Sbjct: 70 IGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPAITLAGPATRTSL 129 Query: 139 PPGTTCTVSGWGTTT-SPDVTFPSDLMCVDVKLISPQDCTKVYKDLL----ENSMLCAGI 193 P T TV+GWG T S F L VDV L+S C V + + ++ CA Sbjct: 130 PALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNSTNFCAA- 188 Query: 194 PDSKKNACNGDSGGPLVCR-GTLQ-GLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 K++C GD+GGP+V + G Q G+VSWG C + GVYT V F WI Sbjct: 189 -RLTKDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWI 241 >3LC3-A nrPDB Length = 235 Score = 99.4 bits (246), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 69/235 (29%), Positives = 109/235 (46%), Gaps = 16/235 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN--EYTVHLGSDTLGD 87 ++ G G PWQV L CGG +VNE+W++TAAHC + TV G + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 88 RR--AQRIKASKSFRHPGY--STQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP---- 139 Q+ + H Y + + +D+ L++L+ L+S V + + + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFL 120 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 + VSGWG + L + V L+ C + K + N+M CAG + ++ Sbjct: 121 KFGSGYVSGWGRVFHKGRS-ALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRD 179 Query: 200 ACNGDSGGPLV--CRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +C GDSGGP V GT L G++SWG C G+YT+V ++ WI + K Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAMKGKYGIYTKVSRYVNWIKEKTK 233 >3I77-A nrPDB Length = 230 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 70/234 (29%), Positives = 110/234 (47%), Gaps = 19/234 (8%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSD 83 ++ G A+G P+ V L++ N+ CGG L + VLTAAHC T G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 84 TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTT 143 L A +++++K + PG++ +T+ D L+KL ++ ++ + T Sbjct: 61 DLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTL----KIATTTAYNQGT 116 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL-ENSMLCAGIPDSKK-NAC 201 TV+GWG + L+ +V +S C +L N M+CAG PD+ + C Sbjct: 117 FTVAGWGANREGG-SQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGGVDTC 175 Query: 202 NGDSGGPLVCRGTLQ-----GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 GDSGGP+ + G+VSWG + C +P PGVYT+V F I + Sbjct: 176 QGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFASAIASAAR 228 >1FUJ-A nrPDB Length = 221 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 69/232 (29%), Positives = 110/232 (47%), Gaps = 22/232 (9%) Query: 30 IIDGAPCARGSHPWQVAL-LSGN--QLHCGGVLVNERWVLTAAHC----KMNEYTVHLGS 82 I+ G S P+ +L + GN CGG L++ +VLTAAHC V LG+ Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 83 DTLGDRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP- 139 + + Q ++ F + Y + +ND++L++L+S A LS+ V V+LP + +P Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 140 -PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKK 198 GT C GWG + D P + ++ + V +C +P K Sbjct: 120 PHGTQCLAMGWGRVGAHD---PPAQVLQELNV-------TVVTFFCRPHNICTFVPRRKA 169 Query: 199 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 C GDSGGPL+C G +QG+ S+ + C P +T+V + WI T++ Sbjct: 170 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >5KWM-A nrPDB Length = 230 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 64/217 (29%), Positives = 99/217 (45%), Gaps = 8/217 (3%) Query: 30 IIDGAPCARGSHPWQVALLSGN-QLHCGGVLVNERWVLTAAHCKMN----EYTVHLGSDT 84 I+ G HP+ VAL++ + Q CGG L V+TAAHC + + V G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + K + + HP Y D+ ++ L + + + ++ + P T Sbjct: 61 MSSNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVK-EAPIELAKADDAGYAPDTAA 119 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 T+ GWG T S L V + S C + Y + ++M+CAG+P+ + C GD Sbjct: 120 TILGWGNT-SEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDTCQGD 178 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKF 241 SGGP+V L G+ SWG C +P PGVY +V + Sbjct: 179 SGGPMVVNNKLIGVTSWGEG-CARPGKPGVYARVGAY 214 >1AKS-B nrPDB Length = 98 Score = 94.4 bits (233), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 42/99 (42%), Positives = 59/99 (59%), Gaps = 1/99 (1%) Query: 154 SPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRG 213 S ++PS L C+ ++S C Y + +M+C G K++C GDSGGP+VC G Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 214 TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 LQG+VSWG + C Q N PGVYT+VC + WI T+ + Sbjct: 61 QLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1ELT-A nrPDB Length = 236 Score = 93.6 bits (231), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 73/241 (30%), Positives = 119/241 (49%), Gaps = 26/241 (10%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLH--CGGVLVNERWVLTAAHC--KMNEYTVHLGSD 83 ++ G S PWQ++L SG+ + CGG L+ + WV+TAAHC + V LG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 84 TL--GDRRAQRIKASKSFRHPGYSTQTHVN--DLMLVKLNSQARLSSMVKKVRLP--SRC 137 L + + Q + + F H G+++ D+ L++LN+QA L+S V+ LP ++ Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 138 EPPGTTCTVSGWGTTTS----PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI 193 P C ++GWG T++ D + L VD S + + ++ +M+CAG Sbjct: 121 LPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSS---SGWWGSTVKTTMVCAG- 176 Query: 194 PDSKKNACNGDSGGPLVCRGT----LQGLVSW-GTFPCGQPNDPGVYTQVCKFTKWINDT 248 + CNGDSGGPL C+ + G+ S+ + C P V+T+V + W+N Sbjct: 177 -GGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGI 235 Query: 249 M 249 M Sbjct: 236 M 236 >2ASU-B nrPDB Length = 234 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 75/240 (31%), Positives = 109/240 (45%), Gaps = 33/240 (13%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHC------KMNEYTVHLGS 82 ++ G P G+ PW V+L + H CGG LV E+W+LTA C + Y V LG+ Sbjct: 1 VVGGHP---GNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 83 ----DTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-- 136 G+ QR+ +K P S L+L+KL L+ V + LP Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGS------QLVLLKLERSVTLNQRVALICLPPEWY 111 Query: 137 CEPPGTTCTVSGWGTT--TSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIP 194 PPGT C ++GWG T T D L+ +IS Q+C ++ + S +C Sbjct: 112 VVPPGTKCEIAGWGETKGTGNDTVLNVALL----NVISNQECNIKHRGRVRESEMCTEGL 167 Query: 195 DSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 + AC GD GGPL C L+G++ C + P V+T+V F WI+ M+ Sbjct: 168 LAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRV-CARSRWPAVFTRVSVFVDWIHKVMR 226 >1PYT-D nrPDB Length = 251 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 77/245 (31%), Positives = 115/245 (46%), Gaps = 30/245 (12%) Query: 29 KIIDGAPCARGSHPWQVAL--LSGNQLH--CGGVLVNERWVLTAAHCKMN--EYTVHLGS 82 +++ G S PWQ++L L N CGG L+ VLTAAHC N Y V LG Sbjct: 13 RVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYRVALGK 72 Query: 83 DTL---GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE- 138 + L + + + F H +++ ND+ L+KL L ++ LPS Sbjct: 73 NNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQVACLPSEGSL 132 Query: 139 -PPGTTCTVSGWG--TTTSPDVTFPSDLM-----CVDVKLISPQDCTKVYKDLLENSMLC 190 P C V+GWG T P ++L VD S +D + ++ +M+C Sbjct: 133 LPQDYPCFVTGWGRLYTNGP---IAAELQQGLQPVVDYATCSQRDW---WGTTVKETMVC 186 Query: 191 AGIPDSKKNACNGDSGGPLVCRG----TLQGLVSWGT-FPCGQPNDPGVYTQVCKFTKWI 245 AG D +ACNGDSGGPL C+ ++G+VS+G+ C P V+T+V + WI Sbjct: 187 AG-GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSAYIDWI 245 Query: 246 NDTMK 250 N ++ Sbjct: 246 NQKLQ 250 >6BQM-A nrPDB Length = 506 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 81/249 (32%), Positives = 114/249 (45%), Gaps = 28/249 (11%) Query: 23 EEAQGDKIIDGAPCARGSHPWQVALLSGNQLH--CGGVLVNERWVLTAAHCKMNEY---- 76 E +II G G P+ VAL + N H CGG + R+VLTAAHC E Sbjct: 4 ESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKG 63 Query: 77 TVHLGSDTLGD-RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS 135 V LG+ + D A+RI + + H Y T + ND+ +++L V+ Sbjct: 64 DVLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSD 123 Query: 136 RCE-PPGTTCTVSGWGTTTSPD--VTFPSDLMC-VDVKLI---------SPQDCTKVYKD 182 E + TV G+G D + P+ ++ V V + S QD Y Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 183 LLENSMLCAGIPDSKKNACNGDSGGPLVC---RGTLQ-GLVSWGTFPCGQPNDPGVYTQV 238 L N+ CAG K+AC+GD+GGP+ G Q G+VSWG CG+ N PGVYT + Sbjct: 184 LTNNA-FCAG--SFGKDACSGDAGGPIFFDSNNGRKQMGVVSWGD-GCGRANSPGVYTNL 239 Query: 239 CKFTKWIND 247 F W++D Sbjct: 240 SVFNDWLDD 248 >4IW4-E nrPDB Length = 279 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 81/268 (30%), Positives = 118/268 (44%), Gaps = 50/268 (18%) Query: 30 IIDGAPCARGSHPWQVALL-------SGNQLHCGGVLVNERWVLTAAHCKMNE------- 75 II G G PWQ ++ ++ G L++ W+LTAAH ++ Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 76 ------YTVHLGSDTLGDRR-AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 TV+LG + D+ A A++ HP ++ Q + +D+ LV+L L V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 129 KKVRLPSRCEPPGTT----CTVSGWGTTTSPDVTFP----------SD-LMCVDVKLISP 173 V LP R EP G V+GWG + +P+VT SD L V + ++ Sbjct: 121 MPVCLP-RLEPEGPAPHMLGLVAGWGIS-NPNVTVDEIISSGTRTLSDVLQYVKLPVVPH 178 Query: 174 QDCTKVYKDLLEN-----SMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSW- 221 +C Y+ N +M CAG + K+ C GDSGG V R +QGLVSW Sbjct: 179 AECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWG 238 Query: 222 GTFPCGQPNDPGVYTQVCKFTKWINDTM 249 G CG GVYT+V + W+ + M Sbjct: 239 GPEECGSKQVYGVYTKVSNYVDWVWEQM 266 >2B9L-A nrPDB Length = 394 Score = 92.0 bits (227), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/247 (29%), Positives = 109/247 (44%), Gaps = 38/247 (15%) Query: 39 GSHPWQVALLSGN--------QLHCGGVLVNERWVLTAAHCKMNEYTVHLGS-------- 82 G PW VA+L N QL CGG L+ VLT AHC +N Y +L + Sbjct: 140 GEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHC-VNSYQSNLDAIKIRAGEW 198 Query: 83 DTLGDRR---AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139 DTL ++ Q K + H ++ +T VND+ L+ L+ + + + LP + + Sbjct: 199 DTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLVQADNIGTICLPQQSQI 258 Query: 140 -PGTTCTVSGWGTTT-SPDVTFPSDLMCVDVKLISPQDCTKVYKD-------LLENSMLC 190 T C SGWG + + L + + + C ++ +L+ + +C Sbjct: 259 FDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLRNTRLGLKFVLDQTFVC 318 Query: 191 AGIPDSKKNACNGDSGGPLVC-------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTK 243 AG + K+ C GD G PL C R G+V+WG CG N PGVY V F Sbjct: 319 AG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWG-IGCGDENVPGVYANVAHFRN 376 Query: 244 WINDTMK 250 WI+ M+ Sbjct: 377 WIDQEMQ 383 >3VGC-B nrPDB Length = 131 Score = 91.7 bits (226), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 50/129 (38%), Positives = 72/129 (55%), Gaps = 6/129 (4%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHLGSDT---L 85 I++G GS PWQV+L H CGG L+NE WV+TAAHC + V + + Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 + Q++K +K F++ Y++ T ND+ L+KL++ A S V V LPS + GTT Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTT 120 Query: 144 CTVSGWGTT 152 C +GWG T Sbjct: 121 CVTTGWGLT 129 >1FON-A nrPDB Length = 240 Score = 89.7 bits (221), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 78/237 (32%), Positives = 110/237 (46%), Gaps = 29/237 (12%) Query: 40 SHPWQVALL---SGNQLH-CGGVLVNERWVLTAAHC--KMNEYTVHLG----SDTLGDRR 89 S WQV+L G H CGG L+ WV+TA HC Y V LG S G + Sbjct: 9 SWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRSVLEGSEQ 68 Query: 90 AQRIKASKSFRHPGYSTQTHV--NDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTTCT 145 I A F HP +++ ND+ LVKL+ A+L V+ LP + P C Sbjct: 69 VIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDILPNEAPCY 128 Query: 146 VSGWGTTTS----PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 +SGWG + PD + L VD + S D + ++ +M+CAG ++ C Sbjct: 129 ISGWGRLYTGGPLPDKLQQALLPTVDYEHCSQWDWWGI---TVKKTMVCAG--GDTRSGC 183 Query: 202 NGDSGGPLVCRGT-----LQGLVSW-GTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 NGDSGGPL C + G+ S+ F C P V+T+V F WI++T+ + Sbjct: 184 NGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETIASN 240 >4KKD-A nrPDB Length = 433 Score = 89.0 bits (219), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 80/269 (29%), Positives = 118/269 (43%), Gaps = 50/269 (18%) Query: 29 KIIDGAPCARGSHPWQVALL-------SGNQLHCGGVLVNERWVLTAAHCKMNE------ 75 +II G G PWQ ++ ++ G L++ W+LTAAH ++ Sbjct: 154 RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTV 213 Query: 76 -------YTVHLGSDTLGDRR-AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSM 127 TV+LG + D+ A A++ HP ++ Q + +D+ LV+L L Sbjct: 214 IPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPH 273 Query: 128 VKKVRLPSRCEP----PGTTCTVSGWGTTTSPDVTFP----------SD-LMCVDVKLIS 172 V V LP R EP P V+GWG + +P+VT SD L V + ++ Sbjct: 274 VMPVCLP-RLEPEGPAPHMLGLVAGWGIS-NPNVTVDEIISSGTRTLSDVLQYVKLPVVP 331 Query: 173 PQDCTKVYKDLLEN-----SMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSW 221 +C Y+ N +M CAG + K+ C GDSG V R +QGLVSW Sbjct: 332 HAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVIFDDLSQRWVVQGLVSW 391 Query: 222 -GTFPCGQPNDPGVYTQVCKFTKWINDTM 249 G CG GVYT+V + W+ + M Sbjct: 392 GGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >1YM0-A nrPDB Length = 238 Score = 88.2 bits (217), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 75/248 (30%), Positives = 112/248 (45%), Gaps = 35/248 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD 87 I+ G PWQV++ S + CGG ++N+RWV+ AAHC E L S +G+ Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPA-LVSLVVGE 59 Query: 88 RRA-------QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP 140 + Q F + Y T ND+ ++K ++ + + C P Sbjct: 60 HDSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIK-----TAVAITFDINVGPICAPD 114 Query: 141 GTTCTV------SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCA-- 191 V SGWGT S V P+ L V + + + C VY D + + M+CA Sbjct: 115 PANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATD 174 Query: 192 --GIPDSKKNACNGDSGGPLVCRG-----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKW 244 G+ D +++C GDSGGPL + +L G+VSWG C PGVY++V W Sbjct: 175 NTGMTD--RDSCQGDSGGPLSVKDGSGIFSLVGIVSWG-IGCASGY-PGVYSRVGFHAGW 230 Query: 245 INDTMKKH 252 I DT+ + Sbjct: 231 ITDTITNN 238 >3BEU-A nrPDB Length = 224 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 65/232 (28%), Positives = 103/232 (44%), Gaps = 21/232 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSDT 84 ++ G A+G P+ V L + CGG L + VLTAAHC T G Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 L A +++++K + PG++ +T+ D L+KL ++ ++ + T Sbjct: 57 LQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQPTL----KIATTTAYNQGTF 112 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL-ENSMLCAGIPDSKKNACNG 203 TV+GWG + L+ +V +S C +L N M+CAG +++ C G Sbjct: 113 TVAGWGANREGG-SQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDTCQG 171 Query: 204 DSGGPLVCRGTLQ-----GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 DSGGP+ + G+VSWG C + GVYT+V F I + Sbjct: 172 DSGGPMFRKDNADEWVQVGIVSWGE-GCARKGKYGVYTEVSTFASAIASAAR 222 >4H4F-A nrPDB Length = 249 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 74/242 (30%), Positives = 115/242 (47%), Gaps = 25/242 (10%) Query: 30 IIDGAPCARGSHPWQVAL--LSGNQLH--CGGVLVNERWVLTAAHCKMN--EYTVHLGSD 83 ++ G S PWQ++L L + CGG L+ +VLTAAHC N Y V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 84 TL---GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 L + + + H ++ ND+ L+KL LS ++ LP + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 139 PPGTTCTVSGWGT--TTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLCAGIP 194 P C V+GWG T P L ++ C+++ + ++ +M+CAG Sbjct: 121 PKDYPCYVTGWGRLWTNGP---IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-G 176 Query: 195 DSKKNACNGDSGGPLVCR---GTLQ--GLVSWGTFP-CGQPNDPGVYTQVCKFTKWINDT 248 D +ACNGDSGGPL C+ G+ + G+VS+G+ C P VYT+V + WIN+ Sbjct: 177 DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEK 236 Query: 249 MK 250 M+ Sbjct: 237 MQ 238 >2V35-A nrPDB Length = 240 Score = 86.7 bits (213), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 113/244 (46%), Gaps = 25/244 (10%) Query: 30 IIDGAPCARGSHPWQVAL--LSGNQLH--CGGVLVNERWVLTAAHCKMNEYT--VHLGSD 83 ++ G R S P Q++L SG+ CGG L+ + WV+TAAHC E T V +G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 84 TL--GDRRAQRIKASKSFRHPGYSTQTHV--NDLMLVKLNSQARLSSMVKKVRLP--SRC 137 L D Q + K HP ++T D+ L++L L+S V+ LP Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 138 EPPGTTCTVSGWGTTTS----PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI 193 + C ++GWG T + + L VD + S + + ++NSM+CAG Sbjct: 121 LANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSS---SSYWGSTVKNSMVCAG- 176 Query: 194 PDSKKNACNGDSGGPLVC----RGTLQGLVSW-GTFPCGQPNDPGVYTQVCKFTKWINDT 248 D ++ C GDSGGPL C + + G+ S+ C P V+T+V + WIN+ Sbjct: 177 GDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNV 236 Query: 249 MKKH 252 + + Sbjct: 237 IASN 240 >2QY0-B nrPDB Length = 242 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 77/253 (30%), Positives = 105/253 (41%), Gaps = 44/253 (17%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC---KMNE------YTVHL 80 II G G+ PWQV + GG L+ +RW+LTAAH K +E V L Sbjct: 1 IIGGQKAKMGNFPWQV--FTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 81 GSDT------LGDRRAQRIKASKSFRHPGYSTQTHVN---DLMLVKLNSQARLSSMVKKV 131 G LG+ +R+ HP Y N D+ L++L + L + + Sbjct: 59 GHTNVEELMKLGNHPIRRVSV-----HPDYRQDESYNFEGDIALLELENSVTLGPNLLPI 113 Query: 132 RLPSR--CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT-----KVYKDLL 184 LP G VSG+G DL V + + +PQ C K D+ Sbjct: 114 CLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRGKNRMDVF 170 Query: 185 ENSMLCAGIPDSKKNACNGDSGG------PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQV 238 +M CAG P K++AC GDSGG P R G+VSWG G G YT+V Sbjct: 171 SQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG---IGCSRGYGFYTKV 227 Query: 239 CKFTKWINDTMKK 251 + WI M++ Sbjct: 228 LNYVDWIKKEMEE 240 >1GPZ-A nrPDB Length = 399 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 78/258 (30%), Positives = 108/258 (41%), Gaps = 44/258 (17%) Query: 26 QGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC---KMNE------Y 76 Q +II G G+ PWQV + GG L+ +RW+LTAAH K +E Sbjct: 154 QRQQIIGGQKAKMGNFPWQV--FTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASL 211 Query: 77 TVHLGSDT------LGDRRAQRIKASKSFRHPGYSTQTHVN---DLMLVKLNSQARLSSM 127 V LG LG+ +R+ HP Y N D+ L++L + L Sbjct: 212 DVFLGHTNVEELMKLGNHPIRRVSV-----HPDYRQDESYNFEGDIALLELENSVTLGPN 266 Query: 128 VKKVRLPSR--CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT-----KVY 180 + + LP G VSG+G + DL V + + +PQ C K Sbjct: 267 LLPICLPDNDTFYDLGLMGYVSGFGVM---EEKIAHDLRFVRLPVANPQACENWLRGKNR 323 Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGG------PLVCRGTLQGLVSWGTFPCGQPNDPGV 234 D+ +M CAG P K++AC GDSGG P R G+VSWG G G Sbjct: 324 MDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGI---GCSRGYGF 380 Query: 235 YTQVCKFTKWINDTMKKH 252 YT+V + WI M++ Sbjct: 381 YTKVLNYVDWIKKEMEEE 398 >2JET-B nrPDB Length = 128 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 50/129 (38%), Positives = 71/129 (55%), Gaps = 12/129 (9%) Query: 33 GAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHL------GSDTL 85 G GS PWQV+L H CGG L++E WV+TAAHC + V + GSD Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSD-- 58 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 + Q +K ++ F++P ++ T ND+ L+KL + A+ S V V LP+ + PPGT Sbjct: 59 -EENIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTV 117 Query: 144 CTVSGWGTT 152 C +GWG T Sbjct: 118 CATTGWGKT 126 >1ELV-A nrPDB Length = 333 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 79/262 (30%), Positives = 114/262 (43%), Gaps = 44/262 (16%) Query: 23 EEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC--KMNEYTVHL 80 EE Q +II G+ + PWQV + GG L+NE WVLTAAH E T+++ Sbjct: 78 EEKQ--RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYV 132 Query: 81 GSDTLGDRRAQRIK---ASKSFRHPGY-------STQTHVNDLMLVKLNSQARLSSMVKK 130 GS ++ R + K F HPG+ ND+ LV+L ++ V Sbjct: 133 GSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIALVRLKDPVKMGPTVSP 192 Query: 131 VRLPSRCEP----PGTTCTVSGWGTTTSPD-------VTFPSDLM--CVDVKLISPQDCT 177 + LP G +SGWG T D P + C +VK+ P Sbjct: 193 ICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 252 Query: 178 KVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVC-------RGTLQGLVSWGTFPCGQPN 230 + Y + +M+CAG + ++C GDSGG + GLVSWG CG Sbjct: 253 EAY--VFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-QCGT-- 306 Query: 231 DPGVYTQVCKFTKWINDTMKKH 252 G+YT+V + WI TM+++ Sbjct: 307 -YGLYTRVKNYVDWIMKTMQEN 327 >1MD7-A nrPDB Length = 328 Score = 84.7 bits (208), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 77/256 (30%), Positives = 106/256 (41%), Gaps = 44/256 (17%) Query: 26 QGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC---KMNE------Y 76 Q +II G G+ PWQV + GG L+ +RW+LTAAH K +E Sbjct: 86 QRQRIIGGQKAKMGNFPWQV--FTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASL 143 Query: 77 TVHLGSDT------LGDRRAQRIKASKSFRHPGYSTQTHVN---DLMLVKLNSQARLSSM 127 V LG LG+ +R+ HP Y N D+ L++L + L Sbjct: 144 DVFLGHTNVEELMKLGNHPIRRVSV-----HPDYRQDESYNFEGDIALLELENSVTLGPN 198 Query: 128 VKKVRLPSR--CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT-----KVY 180 + + LP G VSG+G DL V + + +PQ C K Sbjct: 199 LLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRGKNR 255 Query: 181 KDLLENSMLCAGIPDSKKNACNGDSGG------PLVCRGTLQGLVSWGTFPCGQPNDPGV 234 D+ +M CAG P K++AC GD+GG P R G+VSWG G G Sbjct: 256 MDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWGI---GCSRGYGF 312 Query: 235 YTQVCKFTKWINDTMK 250 YT+V + WI M+ Sbjct: 313 YTKVLNYVDWIKKEME 328 >2HLC-A nrPDB Length = 230 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 65/229 (28%), Positives = 108/229 (47%), Gaps = 20/229 (8%) Query: 30 IIDGAPCARGSHPWQ----VALLSGNQLHCGGVLVNERWVLTAAHCKMNEYT--VHLGSD 83 II+G G P+Q + L ++ CGG L++ +W+LTAAHC + + V+LGS Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 84 TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE----P 139 + A + + + H ++ T++ND+ L+K+ + ++ +RLPS E Sbjct: 61 VQYEGEA-VVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLPSGEELNNKF 118 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDSKK 198 TVSGWG + + V V I C + Y ++ S +C D K Sbjct: 119 ENIWATVSGWGQSNTDTVILQYTYNLV----IDNDRCAQEYPPGIIVESTICGDTSDG-K 173 Query: 199 NACNGDSGGPLVC--RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 + C GDSGGP V + L G+VS+ + + P +++V + WI Sbjct: 174 SPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWI 222 >5UBM-A nrPDB Length = 252 Score = 84.7 bits (208), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 76/256 (29%), Positives = 111/256 (43%), Gaps = 42/256 (16%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC--KMNEYTVHLGSDTLG 86 +II G+ + PWQV + GG L+NE WVLTAAH E T+++GS ++ Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 87 DRRAQRIKA---SKSFRHPGYS-------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 R + K F HPG+ ND+ LV+L ++ V + LP Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 137 CEP----PGTTCTVSGWGTTTSPD-------VTFPSDLM--CVDVKLISPQDCTKVYKDL 183 G +SGWG T D P + C +VK+ P + Y + Sbjct: 118 SSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY--V 175 Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLVC-------RGTLQGLVSWGTFPCGQPNDPGVYT 236 +M+CAG + ++C GDSGG + GLVSWG CG G+YT Sbjct: 176 FTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-QCGT---YGLYT 230 Query: 237 QVCKFTKWINDTMKKH 252 +V + WI TM+++ Sbjct: 231 RVKNYVDWIMKTMQEN 246 >3H7T-A nrPDB Length = 235 Score = 82.8 bits (203), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 65/236 (27%), Positives = 110/236 (46%), Gaps = 24/236 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 II G PW V +L + CGG ++ +V+TAA C K ++ ++H GS + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS-SY 59 Query: 86 GDRRAQRIKASKSF---RHPGYSTQTHVNDLMLVKLNSQARLSS-MVKKVRLPSRC-EP- 139 + + A K + HP T N+ +++ +L KK+ LPS +P Sbjct: 60 RTTKGTSVMAKKIYIVRYHP----LTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPE 115 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-----LENSMLCAGIP 194 P T+ VSGWG+T + + DLM + ++ + C + YK + + + + CAG Sbjct: 116 PDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGE 175 Query: 195 DSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPND-PGVYTQVCKFTKWINDTM 249 + GD+G P V GTL G+ S+ + P++ P V+ +V + I D + Sbjct: 176 YDETYIGYGDAGDPAVQNGTLVGVASYIS---SMPSEFPSVFLRVGYYVLDIKDII 228 >2KAI-A nrPDB Length = 80 Score = 81.6 bits (200), Expect = 3e-16, Method: Composition-based stats. Identities = 38/78 (48%), Positives = 47/78 (60%), Gaps = 2/78 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 II G C + SHPWQVA+ + CGGVLVN +WVLTAAHCK + Y V LG L + Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 88 RRAQRIKASKSFRHPGYS 105 AQ + F HPG++ Sbjct: 61 NTAQFFGVTADFPHPGFN 78 >4J1Y-A nrPDB Length = 397 Score = 81.6 bits (200), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 80/278 (28%), Positives = 119/278 (42%), Gaps = 45/278 (16%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP + + + E E+A + I G+ + PWQV + GG L+NE WVL Sbjct: 127 LPKCVPVCGVPREPFEEKA---RAIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVL 180 Query: 67 TAAHC--KMNEYTVHLGSDTLGDRRAQRIK---ASKSFRHPGYS-------TQTHVNDLM 114 TAAH E T+++GS ++ R + K F HPG+ ND+ Sbjct: 181 TAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIA 240 Query: 115 LVKLNSQARLSSMVKKVRLPSRCEP----PGTTCTVSGWGTTTSPD-------VTFPSDL 163 LV+L ++ V + LP G +SGWG T D P Sbjct: 241 LVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAP 300 Query: 164 M--CVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVC-------RGT 214 + C +VK+ P + Y + +M+CAG + ++C GDSGG + Sbjct: 301 LRKCKEVKVEKPTADAEAY--VFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFY 357 Query: 215 LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GLVSWG CG G+YT+V + WI TM+++ Sbjct: 358 AAGLVSWGP-QCGT---YGLYTRVKNYVDWIMKTMQEN 391 >2FMJ-A nrPDB Length = 222 Score = 80.9 bits (198), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 65/232 (28%), Positives = 99/232 (42%), Gaps = 23/232 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSDT 84 ++ G A+G P+ V L + CGG L + VLTAAHC T G Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 L A +++++K + PGY+ D L+KL ++ ++ + T Sbjct: 57 LQSSSAVKVRSTKVLQAPGYNGTGK--DWALIKLAQPINQPTL----KIATTTAYNQGTF 110 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDSKKNACNG 203 TV+GWG + L+ +V +S C Y +L+ N +CAG + C G Sbjct: 111 TVAGWGANREGG-SQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDTCQG 169 Query: 204 DSGGPLVCRGTLQ-----GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 DSGGP+ + G+VSWG C + GVYT+V F I + Sbjct: 170 DSGGPMFRKDNADEWIQVGIVSWGE-GCARKGKYGVYTEVSTFASAIASAAR 220 >1PPF-E nrPDB Length = 218 Score = 80.1 bits (196), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 58/216 (26%), Positives = 96/216 (44%), Gaps = 17/216 (7%) Query: 42 PWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVH----LGSDTLGDRRAQR-IKAS 96 P+ V+L CG L+ +V++AAHC N LG+ L R R + A Sbjct: 13 PFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAV 72 Query: 97 KSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS--RCEPPGTTCTVSGWGTTTS 154 + GY +ND+++++LN A +++ V+ +LP+ R G C GWG Sbjct: 73 QRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGR 132 Query: 155 PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGT 214 + S L ++V +++ L S +C + + C GDSG PLVC G Sbjct: 133 -NRGIASVLQELNVTVVT---------SLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGL 182 Query: 215 LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 + G+ S+ C P + V +F WI+ ++ Sbjct: 183 IHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1M9U-A nrPDB Length = 241 Score = 79.0 bits (193), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 75/242 (30%), Positives = 113/242 (46%), Gaps = 27/242 (11%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLH-CGGVLVNERWVLTAAHCKM----NEYTVHLG- 81 +I G + G PWQ++ SG+ H CG L++ L+A+HC N V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 82 ---SDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC- 137 SDT G + A + + + G T ++ ND+ ++ L + L ++ LP+ Sbjct: 61 WQQSDTSGTQTA-NVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNN 119 Query: 138 -EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL----LENSMLCAG 192 + GTTC +SGWG T + P L + +I+ CT + + ++ +C Sbjct: 120 NDYAGTTCVISGWGRTDGTN-NLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQ 178 Query: 193 IPDSKKNACNGDSGGPLVC--RGT-LQGLVSW----GTFPCGQPNDPGVYTQVCKFTKWI 245 P ACNGDSGGPL C GT + G+ SW G C P+ P VYT+V + WI Sbjct: 179 DPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVYTRVSAYLGWI 237 Query: 246 ND 247 D Sbjct: 238 GD 239 >4BXW-A nrPDB Length = 423 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 65/245 (26%), Positives = 107/245 (43%), Gaps = 24/245 (9%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQ-LHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD 87 +I++G C G PWQ AL+ + + CGG +++ +VLTAAHC T+ + + Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 88 RRAQ--------RIKASKSFRHP----GYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS 135 R + +I K F P + + D+ ++++ + + S V LP+ Sbjct: 229 SRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPT 288 Query: 136 -----RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLC 190 + VSG+G + L + V + C + + +M C Sbjct: 289 ADFANQVLMKQDFGIVSGFGRIVEKGPKSKT-LKVLKVPYVDRHTCMVSSETPITPNMFC 347 Query: 191 AGIPDSKKNACNGDSGGP--LVCRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 AG ++AC GDSGGP V R T + G+VS G C + G YT++ KF WI Sbjct: 348 AGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGE-GCARNGKYGNYTKLSKFIPWIK 406 Query: 247 DTMKK 251 M++ Sbjct: 407 RIMRQ 411 >4X0L-C nrPDB Length = 259 Score = 75.5 bits (184), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 64/254 (25%), Positives = 107/254 (42%), Gaps = 38/254 (14%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA-HCKMNEYTVHLGSD---- 83 +I+ G A+GS PWQ ++S + L G L+NE+W+LT A + +N D Sbjct: 14 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPT 73 Query: 84 -TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-CEPPG 141 TL + Q ++ K HP YS D+ L+KL + ++ V + LPS+ G Sbjct: 74 LTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDYAEVG 129 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-----------------LL 184 VSGWG + + F L V + + C + Y+ +L Sbjct: 130 RVGYVSGWG--RNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPIL 187 Query: 185 ENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPGVYTQV 238 CAG+ +++ C GD+G + G++S+ C + GVY +V Sbjct: 188 NEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDK-SCAVA-EYGVYVKV 245 Query: 239 CKFTKWINDTMKKH 252 W+ T+ ++ Sbjct: 246 TSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 74.7 bits (182), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 64/257 (24%), Positives = 106/257 (41%), Gaps = 44/257 (17%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD- 87 +I+ G A+GS PWQ ++S + L G L+NE+W+LT A N + H + T D Sbjct: 70 RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA---KNLFLNHSENATAKDI 126 Query: 88 --------RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-CE 138 + Q ++ K HP YS D+ L+KL + ++ V + LPS+ Sbjct: 127 APTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNERVMPICLPSKDYA 182 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD---------------- 182 G VSGWG + F L V + + C + Y+ Sbjct: 183 EVGRVGYVSGWGRNA--NFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQ 240 Query: 183 -LLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQ------GLVSWGTFPCGQPNDPGVY 235 +L CAG+ +++ C GD+G + G++S+ C + GVY Sbjct: 241 PILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDK-SCAVA-EYGVY 298 Query: 236 TQVCKFTKWINDTMKKH 252 +V W+ T+ ++ Sbjct: 299 VKVTSIQDWVQKTIAEN 315 >4F4O-C nrPDB Length = 347 Score = 73.2 bits (178), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 64/254 (25%), Positives = 108/254 (42%), Gaps = 38/254 (14%) Query: 26 QGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA-HCKMNEYTVHLGSDT 84 Q +I+ G+ A+GS PWQ ++S + L G L+NE+W+LT A + ++ D Sbjct: 99 QVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAKNLRLGHKNDTKAKDI 158 Query: 85 -----LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-CE 138 L + Q ++ K HP ST D+ L+KL + ++ V + LPS+ Sbjct: 159 APTLRLYVGKKQEVEIEKVIFHPDNSTV----DIGLIKLKQKVPVNERVMPICLPSKDYV 214 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD---------------- 182 G VSGWG + ++ F L V + + + C + Y+ Sbjct: 215 NVGLVGYVSGWG--RNANLNFTEHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKSPVGVQ 272 Query: 183 -LLENSMLCAGIPDSKKNACNGDSGGPLVCRGT------LQGLVSWGTFPCGQPNDPGVY 235 +L CAG+ +++ C GD+G G++S+ C + + GVY Sbjct: 273 PILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDK-SC-RTAEYGVY 330 Query: 236 TQVCKFTKWINDTM 249 +V WI T+ Sbjct: 331 VRVTSILDWIQTTI 344 >3H7O-A nrPDB Length = 228 Score = 67.8 bits (164), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 61/224 (27%), Positives = 102/224 (45%), Gaps = 22/224 (9%) Query: 42 PWQVALLS---GNQLHCGGVLVNERWVLTAAHCKMNE----YTVHLGSDTLGDRRAQRIK 94 PW VA+ + L CGG ++++ +VLTAAHC ++ + S L + + Sbjct: 12 PWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTNLWEDPGKSDP 71 Query: 95 ASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKK-VRLPSRCEPP--GTTCTVSGWGT 151 Y +T ND+ +++L+ +L + K +LP P G+ VSG+G Sbjct: 72 YVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKTGSDVLVSGYGD 131 Query: 152 TTSPDVTFPSDLMCVDVKLISPQDC-TKVYKDLLENSMLCA---GIPDSKKNACNGDSGG 207 + D DL + ++ +C TK L + CA G+ + +GD+G Sbjct: 132 GQTMDPK-DHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCAQKVGV-----SLESGDAGD 185 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 P V + TL G+ ++ FP P V+T+V + WI D +KK Sbjct: 186 PTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >1RIW-B nrPDB Length = 147 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 47/143 (32%), Positives = 70/143 (48%), Gaps = 21/143 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRL 133 V +G S T +R ++I K + HP Y+ + +++ D+ L+KL S + V L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 134 PSR-----CEPPGTTCTVSGWGT 151 P R G V+GWG Sbjct: 121 PDRETAASLLQAGYKGRVTGWGN 143 >3RU4-E nrPDB Length = 96 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 7/97 (7%) Query: 160 PSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRG----TL 215 P L + L+S +C K + ++++M+CAG S ++C GDSGGPLVC+ TL Sbjct: 3 PDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGA--SGVSSCMGDSGGPLVCKKNGAWTL 60 Query: 216 QGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 G+VSWG+ C + PGVY +V W+ T+ + Sbjct: 61 VGIVSWGSSTC-STSTPGVYARVTALVNWVQQTLAAN 96 >1BBR-H nrPDB Length = 150 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 46/142 (32%), Positives = 72/142 (50%), Gaps = 21/142 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHC----------KMNEYT 77 I++G G PWQV L S +L CG L+++RWVLTAAHC +++ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VHLG--SDTLGDRRAQRIKA-SKSFRHPGYSTQTHVN-DLMLVKLNSQARLSSMVKKVRL 133 V +G S T +R+ ++I K + HP Y+ + +++ D+ L+KL LS + V L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 134 P-----SRCEPPGTTCTVSGWG 150 P ++ G V+GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWG 142 >1EPT-B nrPDB Length = 82 Score = 63.2 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 30/62 (48%), Positives = 38/62 (61%) Query: 91 QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWG 150 Q I A+K HP ++ T ND+ML+KL+S A L+S V V LP C GT C +SGWG Sbjct: 20 QFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAAAGTECLISGWG 79 Query: 151 TT 152 T Sbjct: 80 NT 81 >2JET-C nrPDB Length = 99 Score = 62.4 bits (150), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 7/97 (7%) Query: 160 PSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRG----TL 215 P L + ++S DC K + + + M CAG S ++C GDSGGPLVC+ TL Sbjct: 6 PEKLQQAALPIVSEADCKKSWGSKITDVMTCAGA--SGVDSCMGDSGGPLVCQKDGVWTL 63 Query: 216 QGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 G+VSWG+ C + PGVY++V W+ ++ + Sbjct: 64 AGIVSWGSGVC-STSTPGVYSRVTALMPWVQQILEAN 99 >2I6S-A nrPDB Length = 517 Score = 62.0 bits (149), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 54/228 (23%), Positives = 101/228 (44%), Gaps = 44/228 (19%) Query: 42 PWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQ---RIKASKS 98 PW V + +Q C G L++++WVLTAAHC + L +GD ++Q K+ Sbjct: 244 PWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGDPKSQWGKEFLIEKA 303 Query: 99 FRHPGYST---------QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-------PPGT 142 PG+ + + +D+ L+KL + ++S+ + + LP E P G+ Sbjct: 304 VISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPCTMEANLALRRPQGS 363 Query: 143 TC-----TVSGWGTTTSPDVTFPSDLMCVDVKL-ISPQDCTKV-------------YKDL 183 TC + + + V + +++K+ + C +V +++ Sbjct: 364 TCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQEKTMFPNLTDVREV 423 Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQ----GLVSWGTF-PC 226 + + LC+G + ++ C G+SGG + + GLVSWG + PC Sbjct: 424 VTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWGLYNPC 470 >2HNT-F nrPDB Length = 105 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 10/102 (9%) Query: 160 PSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI-PDSKK--NACNGDSGGPLVCRGTLQ 216 PS L V++ ++ C + + ++M CAG PD K +AC GDSGGP V + Sbjct: 3 PSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFN 62 Query: 217 ------GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 G+VSWG C + G YT V + KWI + + Sbjct: 63 NRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVIDQF 103 >1DLE-A nrPDB Length = 298 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 59/231 (25%), Positives = 96/231 (41%), Gaps = 50/231 (21%) Query: 41 HPWQ--VALLSGNQLH--CGGVLVNERWVLTAAHCKMNEYTVH-LGSDTLGDRRAQRIKA 95 PWQ ++++ ++ H C G +V+E +VLTAAHC + H + G++R I+ Sbjct: 27 QPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEV 86 Query: 96 SKSFRHPGYST---------QTHVNDLMLVKLNSQARLSSMVKKVRLP-----SRC--EP 139 HP Y+ + + D+ L+KL ++ + ++ + LP +R P Sbjct: 87 --VLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLP 144 Query: 140 PGTTCTVSGWGTTTSPDVT--FPSDLM------------------CV-DVKLISPQDCTK 178 P TTC + D+ F S+ C D + D K Sbjct: 145 PTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVK 204 Query: 179 VYKDLLENSMLCAG--IPDSKKNACNGDSGGPLVC----RGTLQGLVSWGT 223 +++ LC G P + N C GDSGGPL+ R G++SWG Sbjct: 205 DISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 255 >1BBR-E nrPDB Length = 109 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 10/101 (9%) Query: 160 PSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI---PDSKKNACNGDSGGPLVC----- 211 PS L V++ L+ C + + ++M CAG + +AC GDSGGP V Sbjct: 7 PSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYN 66 Query: 212 -RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 R G+VSWG C + G YT V + KWI + + Sbjct: 67 NRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2WIN-I nrPDB Length = 507 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 60/235 (25%), Positives = 97/235 (41%), Gaps = 58/235 (24%) Query: 41 HPWQ--VALLSGNQLH--CGGVLVNERWVLTAAHC-----KMNEYTVHLGSDTLGDRRAQ 91 PWQ ++++ ++ H C G +V+E +VLTAAHC K + V +G G++R Sbjct: 234 QPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG----GEKRDL 289 Query: 92 RIKASKSFRHPGYST---------QTHVNDLMLVKLNSQARLSSMVKKVRLP-----SRC 137 I+ HP Y+ + + D+ L+KL ++ + ++ + LP +R Sbjct: 290 EIEV--VLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 347 Query: 138 --EPPGTTCTVSGWGTTTSPDVT--FPSDLMCV-------------------DVKLISPQ 174 PP TTC + D+ F S+ D + Sbjct: 348 LRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGY 407 Query: 175 DCTKVYKDLLENSMLCAG--IPDSKKNACNGDSGGPLVC----RGTLQGLVSWGT 223 D K +++ LC G P + N C GDSGGPL+ R G++SWG Sbjct: 408 DKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGV 462 >2OK5-A nrPDB Length = 752 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 61/234 (26%), Positives = 98/234 (41%), Gaps = 58/234 (24%) Query: 41 HPWQ--VALLSGNQLH--CGGVLVNERWVLTAAHC-----KMNEYTVHLGSDTLGDRRAQ 91 PWQ ++++ ++ H C G +V+E +VLTAAHC K + V +G G++R Sbjct: 478 QPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG----GEKRDL 533 Query: 92 RIKASKSFRHPGYST---------QTHVNDLMLVKLNSQARLSSMVKKVRLP-----SRC 137 I+ HP Y+ + + D+ L+KL ++ + ++ + LP +R Sbjct: 534 EIEV--VLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRA 591 Query: 138 --EPPGTTCTVSGWGTTTSPDVT--FPSDLM------------------CV-DVKLISPQ 174 PP TTC + D+ F S+ C D + Sbjct: 592 LRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGY 651 Query: 175 DCTKVYKDLLENSMLCAG--IPDSKKNACNGDSGGPLVC----RGTLQGLVSWG 222 D K +++ LC G P + N C GDSGGPL+ R G++SWG Sbjct: 652 DKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 >2HNT-C nrPDB Length = 70 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 2/44 (4%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHC 71 I++G+ G PWQV L S +L CG L+++RWVLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHC 44 >3F1S-B nrPDB Length = 283 Score = 41.2 bits (95), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 52/222 (23%), Positives = 83/222 (37%), Gaps = 25/222 (11%) Query: 42 PWQVALL-SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQ---RIKASK 97 PWQV L S + CGGV++ E +VLT A C + + + T +R +Q IK + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV--KTYFNRTSQDPLMIKITH 122 Query: 98 SFRHPGYSTQTHVNDLMLVKLN-----SQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTT 152 H Y NDL L++L A L + P T +SGW Sbjct: 123 VHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARN 182 Query: 153 TSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG-----DSGG 207 + + L V L+ ++C +V + C + + +G + G Sbjct: 183 GT---DLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRG 239 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 G L G+ P G + T+V +++ W M Sbjct: 240 SWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 >3H5C-B nrPDB Length = 317 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 52/223 (23%), Positives = 83/223 (37%), Gaps = 25/223 (11%) Query: 42 PWQVALL-SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQ---RIKASK 97 PWQV L S + CGGV++ E +VLT A C + + + T +R +Q IK + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV--KTYFNRTSQDPLMIKITH 163 Query: 98 SFRHPGYSTQTHVNDLMLVKLN-----SQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTT 152 H Y NDL L++L A L + P T +SGW Sbjct: 164 VHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARN 223 Query: 153 TSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG-----DSGG 207 + + L V L+ ++C +V + C + + +G + G Sbjct: 224 GT---DLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRG 280 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 G L G+ P G + T+V +++ W M Sbjct: 281 SWFLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIMN 317 >4EXK-A nrPDB Length = 487 Score = 34.3 bits (77), Expect = 0.048, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 16/88 (18%) Query: 154 SPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRG 213 SPD+T +M +D ++SP E++ + + D N N V R Sbjct: 378 SPDLT----VMSIDKSVLSPG----------ESATITTIVKDIDGNPVNEVHINKTVARE 423 Query: 214 TLQGLVSWGTFPCGQPNDPGVYTQVCKF 241 L+GL +G P + N PG YTQV + Sbjct: 424 NLKGLWDYG--PLKKENVPGKYTQVITY 449 >4XZ3-B nrPDB Length = 230 Score = 32.3 bits (72), Expect = 0.18, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 9/59 (15%) Query: 152 TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLV 210 SP V SD+ V V L S ++ K Y++++EN K+N N + G LV Sbjct: 61 IVSPQVVHKSDVGGVKVNLRSEEEVRKAYREIIEN---------VKRNVPNAEIEGILV 110 >2OCI-A nrPDB Length = 254 Score = 32.0 bits (71), Expect = 0.27, Method: Compositional matrix adjust. Identities = 25/103 (24%), Positives = 36/103 (34%), Gaps = 9/103 (8%) Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 G+G + PD FP+D D K D + K L + G D A + Sbjct: 61 GYGHSRPPDRDFPADFFERDAK-----DAVDLMKALKFKKVSLLGWSDGGITALIAAAKY 115 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 P + +V WG D +Y + +KW T K Sbjct: 116 P----SYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSERTRK 154 >4G7Y-S nrPDB Length = 185 Score = 30.8 bits (68), Expect = 0.58, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 9/74 (12%) Query: 14 LSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM 73 ++LAL G +I P ++PW+VA G+++ +V+T + + Sbjct: 75 MALALSCYFMLDLGLRIFAYGPKNFFTNPWEVA---------DGLIIVVTFVVTIFYTVL 125 Query: 74 NEYTVHLGSDTLGD 87 +EY G+D LG+ Sbjct: 126 DEYVQETGADGLGE 139 >4G80-S nrPDB Length = 155 Score = 30.0 bits (66), Expect = 0.91, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 9/73 (12%) Query: 14 LSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM 73 ++LAL G +I P ++PW+VA G+++ +V+T + + Sbjct: 64 MALALSCYFMLDLGLRIFAYGPKNFFTNPWEVA---------DGLIIVVTFVVTIFYTVL 114 Query: 74 NEYTVHLGSDTLG 86 +EY G+D LG Sbjct: 115 DEYVQETGADGLG 127 >2VOR-A nrPDB Length = 487 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 5/63 (7%) Query: 150 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 209 G TTSP + P + + +D K ISP Y+++ L A I D + A G GGP Sbjct: 94 GRTTSPHLQSPVERISIDGKPISPAQYVATYREI---EPLVALI-DQQSQASAG-KGGPA 148 Query: 210 VCR 212 + + Sbjct: 149 MSK 151 >6HQB-A nrPDB Length = 751 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 22/54 (40%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Query: 101 HPGYSTQTHVNDLMLVKLNSQARLSSMV-KKVRLPSR--CEPPGT--TCTVSGW 149 H ++ HV L+L+K AR S +V K L R C+ PG TC VSGW Sbjct: 535 HHIHAFTIHVTALILLKGVLYARSSRLVPDKANLGFRFPCDGPGRGGTCQVSGW 588 >5MRT-A nrPDB Length = 205 Score = 28.5 bits (62), Expect = 2.5, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 10/86 (11%) Query: 171 ISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG--DSGGP-LVCRGTLQGLVSWGTFPCG 227 I+ ++ T Y L S L ++ N C G DSGG + G QGL S G P G Sbjct: 119 ITAKNVTVNYGTLGTVSGL------TRANNCTGRGDSGGSWITAAGQAQGLTSGGNLPAG 172 Query: 228 QPNDPGVYT-QVCKFTKWINDTMKKH 252 Q ++ V T Q + + IN + ++ Sbjct: 173 QNDNCSVPTSQRQTYFERINPVLSQY 198 >4FE1-A nrPDB Length = 755 Score = 27.3 bits (59), Expect = 6.0, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 5/54 (9%) Query: 101 HPGYSTQTHVNDLMLVKLNSQARLSSMV-KKVRLPSR--CEPPGT--TCTVSGW 149 H ++ HV L+L+K AR S ++ K L R C+ PG TC VSGW Sbjct: 539 HHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSGW 592 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FXL-A nrPDB 339 6e-94 3BSQ-A nrPDB 339 6e-94 1F7Z-A nrPDB 335 1e-92 4AN7-A nrPDB 333 5e-92 1UTJ-A nrPDB 332 8e-92 5ZFH-A nrPDB 326 8e-90 5C67-A nrPDB 322 8e-89 4WWY-A nrPDB 322 1e-88 1A0J-A nrPDB 321 1e-88 4NFE-A nrPDB 318 2e-87 1SGF-G nrPDB 316 5e-87 1SPJ-A nrPDB 309 1e-84 5MS3-A nrPDB 306 7e-84 1NPM-A nrPDB 304 2e-83 2TLD-E nrPDB 303 5e-83 3QUM-P nrPDB 300 3e-82 1FXY-A nrPDB 297 2e-81 2PSX-A nrPDB 296 5e-81 1AO5-A nrPDB 296 6e-81 1SGF-A nrPDB 294 2e-80 1TON-A nrPDB 294 4e-80 2EEK-A nrPDB 291 2e-79 6QHB-A nrPDB 290 5e-79 1EUF-A nrPDB 286 7e-78 4GSO-A nrPDB 280 6e-76 1FI8-A nrPDB 279 8e-76 1GVZ-A nrPDB 278 2e-75 2AIQ-A nrPDB 277 4e-75 4E7N-A nrPDB 272 9e-74 3T2N-A nrPDB 272 1e-73 2BDH-A nrPDB 270 4e-73 5LPF-A nrPDB 270 4e-73 3S9B-A nrPDB 269 6e-73 5TJX-A nrPDB 269 1e-72 1BQY-A nrPDB 269 1e-72 6I44-A nrPDB 268 2e-72 2CGA-A nrPDB 267 4e-72 5GVT-A nrPDB 267 4e-72 1NN6-A nrPDB 266 5e-72 3S69-A nrPDB 266 5e-72 1OP0-A nrPDB 266 6e-72 4DGJ-A nrPDB 265 9e-72 1IAU-A nrPDB 265 2e-71 1P57-B nrPDB 263 5e-71 3W94-A nrPDB 263 5e-71 1EKB-B nrPDB 263 6e-71 3LC3-A nrPDB 262 8e-71 2F83-A nrPDB 262 1e-70 3G01-A nrPDB 261 2e-70 1X7A-C nrPDB 261 2e-70 1KIG-H nrPDB 260 5e-70 3K65-B nrPDB 258 1e-69 5UGG-A nrPDB 258 2e-69 3NXP-A nrPDB 258 2e-69 1MKW-K nrPDB 257 2e-69 4DUR-A nrPDB 257 3e-69 3DFJ-A nrPDB 256 6e-69 3E0N-B nrPDB 256 6e-69 4NZQ-A nrPDB 256 6e-69 3TK9-A nrPDB 256 7e-69 1BRU-P nrPDB 256 8e-69 2F91-A nrPDB 252 8e-68 2OCV-B nrPDB 252 1e-67 1FDP-A nrPDB 252 1e-67 4Z6A-H nrPDB 252 2e-67 1C5M-D nrPDB 251 2e-67 3P8G-A nrPDB 251 2e-67 6AOD-C nrPDB 250 3e-67 4MPW-A nrPDB 250 3e-67 1BDA-A nrPDB 250 4e-67 4H4F-A nrPDB 250 4e-67 1ETT-H nrPDB 249 9e-67 5XRF-A nrPDB 248 1e-66 1LTO-A nrPDB 248 2e-66 1VR1-H nrPDB 247 3e-66 1SC8-U nrPDB 247 4e-66 1MZD-A nrPDB 247 5e-66 1KYN-A nrPDB 246 6e-66 1PYT-D nrPDB 246 9e-66 3F6U-H nrPDB 246 9e-66 4Q7Y-A nrPDB 245 9e-66 2OQ5-A nrPDB 245 1e-65 5FCR-A nrPDB 245 1e-65 1Q3X-A nrPDB 245 1e-65 1AZZ-A nrPDB 244 3e-65 1FUJ-A nrPDB 244 3e-65 3RP2-A nrPDB 243 4e-65 1FIZ-A nrPDB 243 6e-65 1ORF-A nrPDB 243 6e-65 2RDL-A nrPDB 243 7e-65 5LHN-A nrPDB 243 7e-65 4KKD-A nrPDB 241 2e-64 1ZJK-A nrPDB 241 2e-64 1A5I-A nrPDB 241 3e-64 1ELV-A nrPDB 240 3e-64 1YC0-A nrPDB 240 3e-64 1FIW-A nrPDB 240 3e-64 2V35-A nrPDB 240 4e-64 4IGD-A nrPDB 237 3e-63 4XDE-A nrPDB 237 3e-63 5TO3-B nrPDB 237 4e-63 4IW4-E nrPDB 237 5e-63 2R0L-A nrPDB 236 8e-63 4J1Y-A nrPDB 236 9e-63 4FXG-H nrPDB 234 2e-62 1ELT-A nrPDB 232 1e-61 2ZKS-A nrPDB 228 2e-60 2XXL-A nrPDB 227 3e-60 4DJZ-B nrPDB 227 3e-60 1FON-A nrPDB 227 4e-60 2XRC-A nrPDB 223 4e-59 5KWM-A nrPDB 223 8e-59 1GPZ-A nrPDB 222 1e-58 5UBM-A nrPDB 222 1e-58 1EQ9-A nrPDB 221 2e-58 1MD7-A nrPDB 221 2e-58 4BXW-A nrPDB 221 3e-58 5O32-I nrPDB 220 6e-58 4WJG-C nrPDB 219 1e-57 3I77-A nrPDB 215 1e-56 1AE5-A nrPDB 215 2e-56 2OLG-A nrPDB 215 2e-56 4X0L-C nrPDB 214 2e-56 4LK4-A nrPDB 213 7e-56 2QY0-B nrPDB 212 1e-55 1YM0-A nrPDB 212 1e-55 3BEU-A nrPDB 211 2e-55 4F4O-C nrPDB 211 2e-55 1PPF-E nrPDB 208 3e-54 2B9L-A nrPDB 206 5e-54 6BQM-A nrPDB 205 2e-53 2PKA-B nrPDB 205 2e-53 1SI5-H nrPDB 205 2e-53 2FMJ-A nrPDB 204 2e-53 2HLC-A nrPDB 204 3e-53 1PQ7-A nrPDB 204 4e-53 2ASU-B nrPDB 201 2e-52 5XW8-A nrPDB 184 4e-47 3H7T-A nrPDB 181 4e-46 3H7O-A nrPDB 175 2e-44 1M9U-A nrPDB 170 4e-43 3F1S-B nrPDB 159 7e-40 3H5C-B nrPDB 157 5e-39 1AKS-B nrPDB 153 1e-37 3VGC-B nrPDB 151 2e-37 2I6S-A nrPDB 151 3e-37 2JET-B nrPDB 147 4e-36 2WIN-I nrPDB 145 2e-35 1DLE-A nrPDB 143 7e-35 1RIW-B nrPDB 143 9e-35 2OK5-A nrPDB 141 2e-34 1BBR-H nrPDB 139 8e-34 2HNT-F nrPDB 119 2e-27 1BBR-E nrPDB 118 2e-27 2KAI-A nrPDB 118 3e-27 3RU4-E nrPDB 116 8e-27 2JET-C nrPDB 114 4e-26 1EPT-B nrPDB 110 8e-25 2HNT-C nrPDB 73 9e-14 Sequences not found previously or not previously below threshold: 2HNT-E nrPDB 76 1e-14 1P3E-A nrPDB 39 0.002 2OUA-A nrPDB 38 0.004 5ILB-A nrPDB 37 0.010 4FLN-A nrPDB 37 0.010 2EA3-A nrPDB 36 0.012 2PFE-A nrPDB 36 0.013 2SFA-A nrPDB 34 0.062 2SGA-A nrPDB 34 0.078 3LT3-A nrPDB 33 0.11 3H7V-A nrPDB 32 0.18 5MRT-A nrPDB 31 0.36 1DUE-A nrPDB 31 0.65 5UBM-B nrPDB 31 0.69 5JYK-A nrPDB 30 0.83 5ILA-A nrPDB 30 1.1 5MRR-A nrPDB 29 1.5 4I6M-A nrPDB 29 1.7 1HPG-A nrPDB 29 1.8 4FVB-A nrPDB 29 2.0 3W95-A nrPDB 29 2.0 2M5T-A nrPDB 29 2.1 1GBE-A nrPDB 29 2.2 2HRV-A nrPDB 29 2.3 6HQA-B nrPDB 29 2.8 4B6E-A nrPDB 27 7.5 6FE6-A nrPDB 27 9.1 4U01-A nrPDB 27 9.8 4K8B-A nrPDB 27 9.9 >5FXL-A nrPDB Length = 246 Score = 339 bits (871), Expect = 6e-94, Method: Composition-based stats. Identities = 104/244 (42%), Positives = 141/244 (57%), Gaps = 4/244 (1%) Query: 11 ILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70 I L L A DKI+ G C + P+QV+L SG CGG L+N +WV++AAH Sbjct: 5 IFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGY-HFCGGSLINSQWVVSAAH 63 Query: 71 CKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 C + V LG D + + Q I ASKS HP Y++ T ND+ML+KL S A L+S V Sbjct: 64 CYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRV 123 Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM 188 + LP+ C GT C +SGWG T S ++P L C+ ++S C Y + ++M Sbjct: 124 ASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNM 183 Query: 189 LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 CAG + K++C GDSGGP+VC G LQG+VSWG+ C Q N PGVYT+VC + WI T Sbjct: 184 FCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYTKVCNYVSWIKQT 242 Query: 249 MKKH 252 + + Sbjct: 243 IASN 246 >3BSQ-A nrPDB Length = 227 Score = 339 bits (871), Expect = 6e-94, Method: Composition-based stats. Identities = 222/224 (99%), Positives = 222/224 (99%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 60 Query: 90 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 149 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW Sbjct: 61 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 120 Query: 150 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 209 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL Sbjct: 121 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 180 Query: 210 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK H Sbjct: 181 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKHHH 224 >1F7Z-A nrPDB Length = 233 Score = 335 bits (860), Expect = 1e-92, Method: Composition-based stats. Identities = 99/234 (42%), Positives = 140/234 (59%), Gaps = 4/234 (1%) Query: 21 AGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHL 80 A D I+ G C S P+QV+L SG CGG L+N++WV++AAHC + V L Sbjct: 2 AFPVDDDDAIVGGYTCQENSVPYQVSLNSGY-HFCGGSLINDQWVVSAAHCYKSRIQVRL 60 Query: 81 GSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE 138 G + + Q + A+K +HP + +T ND+ML+KL+S +L++ V V LPS C Sbjct: 61 GEHNINVLEGNEQFVNAAKIIKHPNFDRKTLNNDIMLIKLSSPVKLNARVATVALPSSCA 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKK 198 P GT C +SGWG T S V P L C+D L+ DC Y + ++M+C G + K Sbjct: 121 PAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEGGK 180 Query: 199 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 ++C GDSGGP+VC G LQG+VSWG + C P++PGVYT+VC + WI DT+ + Sbjct: 181 DSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 333 bits (854), Expect = 5e-92, Method: Composition-based stats. Identities = 99/233 (42%), Positives = 135/233 (57%), Gaps = 4/233 (1%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLG 81 DKI+ G CA S P+QV+L SG CGG L+N +WV++AAHC + V LG Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSLNSG-SHFCGGSLINSQWVVSAAHCYKSRIQVRLG 59 Query: 82 SDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139 + + Q I A+K HP ++ T ND+ML+KL+S A L+S V V LP C Sbjct: 60 EHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAA 119 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 GT C +SGWG T S ++PS L C+ ++S C Y + +M+C G + K+ Sbjct: 120 AGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKD 179 Query: 200 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 +C GDSGGP+VC G LQG+VSWG + C Q N PGVYT+VC + WI T+ + Sbjct: 180 SCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >1UTJ-A nrPDB Length = 242 Score = 332 bits (852), Expect = 8e-92, Method: Composition-based stats. Identities = 106/244 (43%), Positives = 146/244 (59%), Gaps = 5/244 (2%) Query: 11 ILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70 I L+ + L A + DKI+ G C S P QV+L SG CGG LVNE WV++AAH Sbjct: 2 ISLVFVLLIGAAFATEDDKIVGGYECKPYSQPHQVSLNSGY-HFCGGSLVNENWVVSAAH 60 Query: 71 CKMNEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 C + V LG + + Q I +S+ RHP YS+ ND+ML+KL+ A L++ V Sbjct: 61 CYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSSYNIDNDIMLIKLSKPATLNTYV 120 Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSM 188 + V LP+ C P GT CTVSGWG T S + L C+++ ++S DC Y ++ N+M Sbjct: 121 QPVALPTSCAPAGTMCTVSGWGNTMSSTAD-SNKLQCLNIPILSYSDCNNSYPGMITNAM 179 Query: 189 LCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 CAG + K++C GDSGGP+VC G LQG+VSWG + C +P +PGVY +VC F W+ T Sbjct: 180 FCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFNDWLTST 238 Query: 249 MKKH 252 M + Sbjct: 239 MASY 242 >5ZFH-A nrPDB Length = 224 Score = 326 bits (835), Expect = 8e-90, Method: Composition-based stats. Identities = 170/224 (75%), Positives = 194/224 (86%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 IIDG C GSHPWQVALL GNQLHCGGVLV++ WVLTAAHCKM +Y V LGSD +GD+ Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGDQS 60 Query: 90 AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 149 AQ+IKA+KSFRHPGYST+THVND+MLV+L+ ++SS V+ V+LP CEPPGT+CTVSGW Sbjct: 61 AQKIKATKSFRHPGYSTKTHVNDIMLVRLDEPVKMSSKVEAVQLPEHCEPPGTSCTVSGW 120 Query: 150 GTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPL 209 GTTTSPDVTFPSDLMC DVKLIS ++C KVYKDLL +MLCAGIPDSK N CNGDSGGPL Sbjct: 121 GTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDSKTNTCNGDSGGPL 180 Query: 210 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 VC TLQGLVSWGT+PCGQPNDPGVYTQVCK+ +W+ +TMK HR Sbjct: 181 VCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMKTHR 224 >5C67-A nrPDB Length = 224 Score = 322 bits (826), Expect = 8e-89, Method: Composition-based stats. Identities = 92/225 (40%), Positives = 131/225 (58%), Gaps = 4/225 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C S P+QV+L SG CGG L++E+WV++AAHC V LG + + Sbjct: 1 IVGGYTCEENSLPYQVSLNSG-SHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I A+K RHP Y+ T ND+ML+KL+S A +++ V + LP+ GT C +S Sbjct: 60 GNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTECLIS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S +P +L C+D +++ +C Y + NSM C G + K++C D+GG Sbjct: 120 GWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSCQRDAGG 179 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 P+VC G LQG+VSWG C N PGVYT+V + WI DT+ + Sbjct: 180 PVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 223 >4WWY-A nrPDB Length = 224 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 93/225 (41%), Positives = 133/225 (59%), Gaps = 4/225 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C S P+QV+L SG CGG L+NE+WV++A HC + V LG + + Sbjct: 1 IVGGYNCEENSVPYQVSLNSGY-HFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I A+K RHP Y +T ND+ML+KL+S+A +++ V + LP+ GT C +S Sbjct: 60 GNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAHVSTISLPTAPPATGTKCLIS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S +P +L C+D ++S C Y + ++M C G + K++C DSGG Sbjct: 120 GWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQRDSGG 179 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 P+VC G LQG+VSWG C Q N PGVYT+V + KWI +T+ + Sbjct: 180 PVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAAN 223 >1A0J-A nrPDB Length = 223 Score = 321 bits (824), Expect = 1e-88, Method: Composition-based stats. Identities = 93/225 (41%), Positives = 131/225 (58%), Gaps = 4/225 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S +Q +L SG CGG L++ WV++AAHC + V LG + + Sbjct: 1 IVGGYECRKNSASYQASLQSGY-HFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I + K HP Y+++ ND+ML+KL+ A L+S V V LPS C GT C VS Sbjct: 60 GTEQFIDSVKVIMHPSYNSRNLDNDIMLIKLSKPASLNSYVSTVALPSSCASSGTRCLVS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG + +P L C+D+ ++S C Y + ++M CAG + K++C GDSGG Sbjct: 120 GWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEGGKDSCQGDSGG 179 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 P+VC G LQG+VSWG + C Q N PGVYT+VC + WI+ TM + Sbjct: 180 PVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >4NFE-A nrPDB Length = 237 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 99/236 (41%), Positives = 133/236 (56%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 I+ G C + S PWQVA+ S HCGGVLV+ +WVLTAAHC V LG L + Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 90 --AQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 QR+ S SF HP Y+ + +DLML++L+ A+++ +VK + LP++ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 GTTC SGWG+ + P L CV + L+S C + Y + + MLCAG+ Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPLVC G LQG+ SWG PC P P VYT+V + KWI DT+ + Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 236 >1SGF-G nrPDB Length = 237 Score = 316 bits (811), Expect = 5e-87, Method: Composition-based stats. Identities = 104/236 (44%), Positives = 142/236 (60%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S PW VA+ Q CGGVL++ WVLTAAHC + Y V LG + L + Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 88 RRAQRIKASKSFRHPGYSTQ-----------THVNDLMLVKLNSQARLSSMVKKVRLPSR 136 AQ SK+ HPG++ + NDLML++L+ A ++ VK + LP+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 G+TC SGWG+ T F DL CV++KL+ +DC K + + + ++MLCAG D Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPL+C G LQG+ SWG PCG+P+ PGVYT++ KFT WI DTM K+ Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKN 236 >1SPJ-A nrPDB Length = 238 Score = 309 bits (791), Expect = 1e-84, Method: Composition-based stats. Identities = 97/237 (40%), Positives = 137/237 (57%), Gaps = 14/237 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 89 I+ G C + S PWQ AL + CGG+LV+ +WVLTAAHC + Y + LG L D Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 90 --AQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQA-RLSSMVKKVRLPS 135 AQ + S+SF HPG++ + + +DLML++L A ++ VK V LP+ Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195 G+TC SGWG+ + +FP DL CVD+K++ +C K + + + MLC G + Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPL+C G LQG+ SWG PCG PN P V +V + KWI DT+ ++ Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 237 >5MS3-A nrPDB Length = 228 Score = 306 bits (784), Expect = 7e-84, Method: Composition-based stats. Identities = 106/225 (47%), Positives = 133/225 (59%), Gaps = 6/225 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 ++ G C S PWQ AL G QL CGGVLV WVLTAAHCK +YTV LG +L D Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 88 RRAQRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 Q I +S HP Y++ + H +DLML++L QA L S VK + L C PG C Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 TVSGWGT TSP FP L C +VK+ + C Y + + M+CAG + C GD Sbjct: 121 TVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQGD 179 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 SGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++ WI + Sbjct: 180 SGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 224 >1NPM-A nrPDB Length = 225 Score = 304 bits (779), Expect = 2e-83, Method: Composition-based stats. Identities = 106/225 (47%), Positives = 143/225 (63%), Gaps = 6/225 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I++G C S PWQ AL G +L CGGVLV +RWVLTAAHCK +Y+V LG +L D Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 88 RRAQRIKASKSFRHPGYS---TQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + Q I+ ++S +HP Y+ + H +D+ML++L + A L VK V+L + C G C Sbjct: 61 QPEQEIQVAQSIQHPCYNNSNPEDHSHDIMLIRLQNSANLGDKVKPVQLANLCPKVGQKC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 +SGWGT TSP FP+ L C +VK+ S C + Y + M+CAG + + C GD Sbjct: 121 IISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNGA-DTCQGD 179 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 SGGPLVC G LQG+ SWG+ PCG+P PGVYT++C++T WI TM Sbjct: 180 SGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >2TLD-E nrPDB Length = 220 Score = 303 bits (776), Expect = 5e-83, Method: Composition-based stats. Identities = 96/225 (42%), Positives = 133/225 (59%), Gaps = 7/225 (3%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C + P+QV+L SG CGG L+N +WV++AAHC + V LG D + + Sbjct: 1 IVGGYTCGANTVPYQVSLNSGY-HFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I ASKS HP Y++ T ND+ML+KL S A L+S V + LP+ C GT C +S Sbjct: 60 GNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLIS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S ++P L C+ ++S C Y + ++M CAG+ ++C GDSGG Sbjct: 120 GWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG--DSCQGDSGG 177 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 P+VC G LQG+VSWG+ C N PGVYT+VC + WI T+ + Sbjct: 178 PVVCSGKLQGIVSWGS-GCA-KNKPGVYTKVCNYVSWIKQTIASN 220 >3QUM-P nrPDB Length = 237 Score = 300 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 97/236 (41%), Positives = 132/236 (55%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L + Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 88 RRAQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 Q + S SF HP Y +DLML++L+ A L+ VK + LP++ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+ + Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 236 >1FXY-A nrPDB Length = 228 Score = 297 bits (762), Expect = 2e-81, Method: Composition-based stats. Identities = 78/228 (34%), Positives = 120/228 (52%), Gaps = 6/228 (2%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCKM--NEYTVHLGSDTLG 86 I+ G C G PWQ L++ N+ CGG +++E ++LTAAHC + V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + +H ++ +T+ D+ +++L + V LP+ GT C Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPASLPTAPPATGTKC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 +SGWG T S +P +L C+D ++S C Y + ++M C G + K++C GD Sbjct: 121 LISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGD 180 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 SGGP+VC G LQG+VSWG C Q N PGVYT+V + KWI +T+ + Sbjct: 181 SGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAAN 227 >2PSX-A nrPDB Length = 227 Score = 296 bits (759), Expect = 5e-81, Method: Composition-based stats. Identities = 109/227 (48%), Positives = 150/227 (66%), Gaps = 5/227 (2%) Query: 30 IIDGAPCARGSHPWQVALL-SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--- 85 II+G+ C + PWQ ALL NQL+CG VLV+ +W+LTAAHC+ + V LG +L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 + Q + KS HPGYS H NDLML+KLN + R + V+ + + S C GT C Sbjct: 61 YESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCL 120 Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205 VSGWGTT SP V FP L C+++ ++S + C Y ++++M CAG + +++C GDS Sbjct: 121 VSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQGDS 179 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++ + Sbjct: 180 GGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 226 >1AO5-A nrPDB Length = 237 Score = 296 bits (759), Expect = 6e-81, Method: Composition-based stats. Identities = 98/236 (41%), Positives = 137/236 (58%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 ++ G C + S PWQVA+ + CGGVL++ WVLTAAHC +++Y V LG + L + Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 88 RRAQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 AQ SKSF HPG++ +DLML++L+ A ++ +VK + LP++ Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 PG+ C SGWG+ T P DL CV + L+ ++C KVY + + MLCAG Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C DSGGPL+C G LQG S+G PCG+P P +YT + KF WI DTM K+ Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 236 >1SGF-A nrPDB Length = 240 Score = 294 bits (753), Expect = 2e-80, Method: Composition-based stats. Identities = 94/231 (40%), Positives = 135/231 (58%), Gaps = 14/231 (6%) Query: 35 PCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GDRRAQR 92 C S PW VA+ N+ CGGVL++ WVLTAAHC ++Y V LG + + Q Sbjct: 10 DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQH 68 Query: 93 IKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPG 141 SK+ HP ++ + NDLML++L+ A ++ +VK + LP+ G Sbjct: 69 RLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLG 128 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 +TC SGWG+TT +P DL CV++KL+ +DC K ++ + ++MLCAG D C Sbjct: 129 STCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTC 188 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 DSGGPL+C G LQG+ SWG PCG+P +P VYT++ KF+ WI +TM + Sbjct: 189 EHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANN 239 >1TON-A nrPDB Length = 235 Score = 294 bits (752), Expect = 4e-80, Method: Composition-based stats. Identities = 100/236 (42%), Positives = 139/236 (58%), Gaps = 15/236 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S PWQVA++ N+ CGGVL++ WV+TAAHC N Y V LG + L + Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 88 RRAQRIKASKSFRHPGYST-----------QTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 AQR +SFRHP Y H NDLML+ L+ A ++ VK + LP++ Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 G+TC SGWG+T ++ DL CV++ L+S + C + YKD + + MLCAG + Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 K+ C GDSGGPL+C G LQG+ S G PC +P P +Y ++ KFT WI MK++ Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKEN 234 >2EEK-A nrPDB Length = 220 Score = 291 bits (746), Expect = 2e-79, Method: Composition-based stats. Identities = 95/223 (42%), Positives = 128/223 (57%), Gaps = 5/223 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 I+ G C + S QV+L SG CGG LV++ WV++AAHC + V LG + + Sbjct: 1 IVGGYECTKHSQAHQVSLNSGY-HFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 88 RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVS 147 Q I +S RHP YS+ ND+ML+KL A L+ V V LP+ C T CTVS Sbjct: 60 GTEQYISSSSVIRHPNYSSYNINNDIMLIKLTKPATLNQYVHAVALPTECAADATMCTVS 119 Query: 148 GWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGG 207 GWG T S V L C+ + ++S DC Y ++ SM CAG + K++C GDSGG Sbjct: 120 GWGNTMSS-VADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEGGKDSCQGDSGG 178 Query: 208 PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 P+VC G LQG+VSWG + C + + PGVY +VC + W+ DTM Sbjct: 179 PVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTMA 220 >6QHB-A nrPDB Length = 223 Score = 290 bits (742), Expect = 5e-79, Method: Composition-based stats. Identities = 93/223 (41%), Positives = 130/223 (58%), Gaps = 4/223 (1%) Query: 31 IDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRA 90 + G PC + SHP+Q AL + L CGGVL++ WVLTAAHCK V LG LG + + Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQES 61 Query: 91 QRIK--ASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSG 148 + + ++ HP Y +H D+ML++L A+LS +++ + L C T+C + G Sbjct: 62 SQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAQTTSCHILG 121 Query: 149 WGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGP 208 WG T D FP + C + L+S ++C Y + +MLCAG K++C GDSGGP Sbjct: 122 WGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGP 179 Query: 209 LVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 LVC L+GLVSWG PCG PGVYT VC++T WI T++ Sbjct: 180 LVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 222 >1EUF-A nrPDB Length = 227 Score = 286 bits (732), Expect = 7e-78, Method: Composition-based stats. Identities = 85/231 (36%), Positives = 124/231 (53%), Gaps = 11/231 (4%) Query: 30 IIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL- 85 II G S P+ LL SG CGG LV E +VLTAAHC + V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 86 -GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR--CEPPGT 142 +R Q I + HP Y+ +T ND+ML+KL +A ++ V + LP PG Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETLANDIMLLKLTRKADITDKVSPINLPRSLAEVKPGM 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACN 202 C+V+GWG + L VD+++ S + C +K+ + + +CAG P +KN+ + Sbjct: 121 MCSVAGWGRLGVNMPST-DKLQEVDLEVQSEEKCIARFKNYIPFTQICAGDPSKRKNSFS 179 Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GDSGGPLVC G QG+VS+G P VYT++ F WI+ TM++++ Sbjct: 180 GDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMRRYK 227 >4GSO-A nrPDB Length = 232 Score = 280 bits (716), Expect = 6e-76, Method: Composition-based stats. Identities = 76/226 (33%), Positives = 115/226 (50%), Gaps = 4/226 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT--LGD 87 ++ G C HP+ L S + CG L+N+ WV+TAAHC + + LG + + + Sbjct: 1 VLGGDECDINEHPFLAFLYS-HGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 88 RRAQRIKASKSFRHPGYSTQT-HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Q + F P + D+ML+KL+ S + + LPS G+ C + Sbjct: 60 EDEQTRNPKEKFICPNKNMSEVLDKDIMLIKLDKPISNSKHIAPLSLPSNPPSVGSVCRI 119 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 GWG+ T P+ T+P C ++ L+ + C Y L + LCAG+ + K+ C GDSG Sbjct: 120 MGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEGGKDTCVGDSG 179 Query: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GPL+C G QG+VS+G CGQ PG+YT V +T WI + + Sbjct: 180 GPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGN 225 >1FI8-A nrPDB Length = 228 Score = 279 bits (714), Expect = 8e-76, Method: Composition-based stats. Identities = 83/231 (35%), Positives = 117/231 (50%), Gaps = 13/231 (5%) Query: 30 IIDGAPCARGSHPWQVALL----SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 85 II G S P+ L CGG L+ E +VLTAAHC ++ V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 86 GDRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC--EPPG 141 ++ Q I K HP Y+++T ND+ML+KL S+A+ SS VK + LP R PG Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTISNDIMLLKLKSKAKRSSAVKPLNLPRRNVKVKPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN-SMLCAGIPDSKKNA 200 C V+GWG + L V++ + Q C K+ + + +CAG P K+ + Sbjct: 121 DVCYVAGWGKLGPMG-KYSDTLQEVELTVQEDQKCESYLKNYFDKANEICAGDPKIKRAS 179 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 GDSGGPLVC+ G+VS+G + P +T+V F WI TMKK Sbjct: 180 FRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTMKK 227 >1GVZ-A nrPDB Length = 237 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 88/236 (37%), Positives = 126/236 (53%), Gaps = 13/236 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 87 II G C + S PWQVA+ CGGVLV+ +WVLTAAHC ++Y + LG L + Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 88 RRAQRIKASKSFRHPGYS-----------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 AQ + S SF P + +DLML++L AR++ VK + LP++ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 G+TC SGWG ++ L CV+++L S + C + Y + + +LCA D Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 + C GDSGG L+C G QG+ SWG C ND V+T+V KWI +T++K+ Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKN 236 >2AIQ-A nrPDB Length = 231 Score = 277 bits (708), Expect = 4e-75, Method: Composition-based stats. Identities = 83/226 (36%), Positives = 117/226 (51%), Gaps = 5/226 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL---G 86 +I G C H + +AL+ N CGG L+N+ WVLTA HC ++LG L Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 +R K F + D+ML++LN R S+ + + LPS G+ C + Sbjct: 60 KDALRRFPKEKYFCLNTRNDTIWDKDIMLIRLNRPVRNSAHIAPLSLPSNPPSVGSVCRI 119 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 GWGT TSP+ T P C ++ ++ C YK L + LCAGI + K+ C GDSG Sbjct: 120 MGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAGILEGGKDTCKGDSG 178 Query: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GPL+C G QG++S G PC QP PG+YT+V +T WI + + Sbjct: 179 GPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGN 224 >4E7N-A nrPDB Length = 238 Score = 272 bits (697), Expect = 9e-74, Method: Composition-based stats. Identities = 79/231 (34%), Positives = 115/231 (49%), Gaps = 8/231 (3%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ--LHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL-- 85 II G C H + VAL + L CGG L+N+ WVLTAAHC + + LG + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 86 -GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + R+ K F + D+ML++L+S + S + LPS G+ C Sbjct: 61 PNEDEQTRVPKEKFFCLSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLPSSPPSVGSVC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL---LENSMLCAGIPDSKKNAC 201 + GWG + + T+P CV++ L+ + C Y + + LCAGI + K+ C Sbjct: 121 RIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCAGILEGGKDTC 180 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPL+C G QG+ SWG PC QP+ P YT+V WI + + + Sbjct: 181 KGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAGN 231 >3T2N-A nrPDB Length = 372 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 86/269 (31%), Positives = 124/269 (46%), Gaps = 26/269 (9%) Query: 8 PLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLT 67 P L ++ + + D+I+ G + G PWQV+L CGG L++ WVLT Sbjct: 96 PRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLT 155 Query: 68 AAHCK------MNEYTVHLGSDTLGDRRAQRIKASKSFRHPGY------STQTHVNDLML 115 AAHC ++ + V G+ ++ H GY +++ + ND+ L Sbjct: 156 AAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIAL 215 Query: 116 VKLNSQARLSSMVKKVRLPSRCEP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISP 173 V L+S L+ ++ V LP+ + G CTV+GWG T L V +IS Sbjct: 216 VHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYG-QQAGVLQEARVPIISN 274 Query: 174 QDCTKV--YKDLLENSMLCAGIPDSKKNACNGDSGGPLVC--------RGTLQGLVSWGT 223 C Y + ++ M CAG P+ +AC GDSGGP VC R L G+VSWG Sbjct: 275 DVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG- 333 Query: 224 FPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 C PGVYT+V F +WI +K H Sbjct: 334 TGCALAQKPGVYTKVSDFREWIFQAIKTH 362 >2BDH-A nrPDB Length = 223 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 105/225 (46%), Positives = 144/225 (64%), Gaps = 5/225 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL---G 86 II+G C+ S PWQ AL+ N+L C GVLV+ +WVL+AAHC N YT+ LG +L Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 + +Q ++AS S RHP Y+ NDLML+KL+ S ++ + + S+C G +C V Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSCLV 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSG 206 SGWG + P+ L CV+V ++S + C+K+Y L SM CAG +K++CNGDSG Sbjct: 121 SGWGLLANG--RMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSG 178 Query: 207 GPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 GPL+C G LQGLVS+G PCGQ PGVYT +CKFT+WI T++ Sbjct: 179 GPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >5LPF-A nrPDB Length = 234 Score = 270 bits (691), Expect = 4e-73, Method: Composition-based stats. Identities = 98/229 (42%), Positives = 136/229 (59%), Gaps = 10/229 (4%) Query: 33 GAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGS-DTLGDRRAQ 91 G+PCARGS PWQV+L +G HC GVLV++ WVLTAAHC +G L + Q Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQGEQ 66 Query: 92 RIKASKSFRHPGYST--------QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTT 143 + ++S HP Y +T +DLML+KL L V+ ++LP RC PG Sbjct: 67 LRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGDQ 126 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG 203 C V+GWGTT + V + L C + ++SP++C Y ++ N+M+CAG D ++ C Sbjct: 127 CQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQDPCQS 185 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 DSGGPLVC TLQG++SWG +PCG P VYTQ+CK+ WIN ++ + Sbjct: 186 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >3S9B-A nrPDB Length = 234 Score = 269 bits (689), Expect = 6e-73, Method: Composition-based stats. Identities = 75/230 (32%), Positives = 116/230 (50%), Gaps = 8/230 (3%) Query: 30 IIDGAPCARGSHPWQVALLSG--NQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT--- 84 ++ G C HP+ VAL + + +HC G L+N WVLTAAHC + LG + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + R+ K F D+ML++L S+ + V LPSR G+ C Sbjct: 61 RNEDEQIRVPRGKYFCLNTKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLPSRSRGVGSRC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN-SMLCAGIPDSKKNACNG 203 + GWG ++ T+P C ++ ++ + C +Y + + LCAGI ++ C+G Sbjct: 121 RIMGWGKISTT--TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGILKGGRDTCHG 178 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 DSGGPL+C G + G+V+ G+ PCGQ P VYT+V + WI + +R Sbjct: 179 DSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGNR 228 >5TJX-A nrPDB Length = 263 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 76/236 (32%), Positives = 119/236 (50%), Gaps = 19/236 (8%) Query: 27 GDKIIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHCK-----MNEYTV 78 +I+ G + G PWQV+L + + CGG L+ +WVLTAAHC + + + Sbjct: 13 STRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 72 Query: 79 HLGSDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 + G L D + + + H Y +D+ L+KL + + K + LPS+ Sbjct: 73 YSGILELSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLEYTEFQKPISLPSK 132 Query: 137 CEPPG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGI 193 + T C V+GWG + + L V++ L++ ++C K Y+D + M+CAG Sbjct: 133 GDTSTIYTNCWVTGWGFSKEKG-EIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGY 191 Query: 194 PDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 + K+AC GDSGGPLVC+ L G+ SWG C + PGVYT+V ++ WI Sbjct: 192 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVAEYMDWI 246 >1BQY-A nrPDB Length = 234 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 78/228 (34%), Positives = 112/228 (49%), Gaps = 4/228 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT---LG 86 + G C H V L + N CGG L+N+ WV+TAAHC N + + G + L Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 + R K F D+ML+KL+S S + + LPS G+ C + Sbjct: 61 EDEQTRDPKEKFFCPNRKKDDEVDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSVCRI 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSKKNACNGDS 205 GWG T +P C ++ ++ C Y + N+ LCAGI ++ C+ DS Sbjct: 121 MGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQGGRDTCHFDS 180 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GGPL+C G QG+VSWG PCGQP +PGVYT+V + WI + ++ Sbjct: 181 GGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGNK 228 >6I44-A nrPDB Length = 627 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 123/250 (49%), Gaps = 19/250 (7%) Query: 13 LLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAA 69 L + + +I+ G + G PWQV+L + + CGG L+ +WVLTAA Sbjct: 363 LCNTGDNSVCTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAA 422 Query: 70 HCK-----MNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQA 122 HC + + ++ G L D + + + H Y +D+ L+KL + Sbjct: 423 HCFDGLPLQDVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPL 482 Query: 123 RLSSMVKKVRLPSRCEPPG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY 180 + + K + LPS+ + T C V+GWG + + L V++ L++ ++C K Y Sbjct: 483 QYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSAEAG-EIQNILQKVNIPLVTNEECQKRY 541 Query: 181 KDL-LENSMLCAGIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVY 235 +D + M+CAG + K+AC GD+GGPLVC+ L G+ SWG C + PGVY Sbjct: 542 QDYKITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVY 600 Query: 236 TQVCKFTKWI 245 T+V ++ WI Sbjct: 601 TKVAEYMDWI 610 >2CGA-A nrPDB Length = 245 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 87/235 (37%), Positives = 128/235 (54%), Gaps = 13/235 (5%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHL-GSDTL 85 +I++G GS PWQV+L H CGG L+NE WV+TAAHC + V + G Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 73 Query: 86 GDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 G Q++K +K F++ Y++ T ND+ L+KL++ A S V V LPS + G Sbjct: 74 GSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAG 133 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 TTC +GWG T + P L + L+S +C K + ++++M+CAG ++C Sbjct: 134 TTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSC 191 Query: 202 NGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPLVC+ TL G+VSWG+ C + PGVY +V W+ T+ + Sbjct: 192 MGDSGGPLVCKKNGAWTLVGIVSWGSSTCST-STPGVYARVTALVNWVQQTLAAN 245 >5GVT-A nrPDB Length = 250 Score = 267 bits (682), Expect = 4e-72, Method: Composition-based stats. Identities = 75/233 (32%), Positives = 114/233 (48%), Gaps = 19/233 (8%) Query: 30 IIDGAPCARGSHPWQVALLSG---NQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLG 81 I+ G + G PWQV+L CGG ++ +WVLTAAHC + + ++ G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 82 SDTLGDRRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139 +L + + + + H Y D+ L+KL + + K + LPS+ + Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVSEGNYDIALIKLQTPLNYTEFQKPISLPSKADT 120 Query: 140 PG--TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDS 196 T C V+GWG T T + L + L+ ++C K Y+D + M+CAG + Sbjct: 121 NTIYTNCWVTGWGYTKEQGET-QNILQKATIPLVPNEECQKKYRDYVINKQMICAGYKEG 179 Query: 197 KKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 +AC GDSGGPLVC R L G+ SWG C + + PGVYT+V ++ WI Sbjct: 180 GTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKVSEYMDWI 231 >1NN6-A nrPDB Length = 228 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 85/233 (36%), Positives = 122/233 (52%), Gaps = 13/233 (5%) Query: 28 DKIIDGAPCARGSHPWQVAL----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSD 83 +II G C S P+ L +G CGG L+ +VLTAAHC TV LG+ Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 84 TLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC--EP 139 + + Q+++ K FRHP Y+T T +D+ML+KL +A L+ V + PS+ P Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLPFPSQFNFVP 120 Query: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 PG C V+GWG T L V ++L+ PQ C+ ++D N LC G P K+ Sbjct: 121 PGRMCRVAGWGRTGVLKPG-SDTLQEVKLRLMDPQACS-HFRDFDHNLQLCVGNPRKTKS 178 Query: 200 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 A GDSGGPL+C G QG+VS+G P V+T++ + WIN ++ + Sbjct: 179 AFKGDSGGPLLCAGVAQGIVSYGRS---DAKPPAVFTRISHYRPWINQILQAN 228 >3S69-A nrPDB Length = 234 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 82/227 (36%), Positives = 113/227 (49%), Gaps = 4/227 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT---LG 86 +I G C H VA + C G L+NE WVLTAAHC + + LG + L Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 + R K + + D+ML+KL+S+ S + + LPS G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKKNDEVLDKDIMLIKLDSRVSNSEHIVPLSLPSSPPSVGSVCHI 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN-SMLCAGIPDSKKNACNGDS 205 GWG+ T VT+P C + L+ C Y +LL LCAGI + K+ C GDS Sbjct: 121 MGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILEGGKDTCGGDS 180 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GGPL+C G QG+VS+G PCGQ PGVYT+V + WI + + Sbjct: 181 GGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGN 227 >1OP0-A nrPDB Length = 234 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 80/227 (35%), Positives = 113/227 (49%), Gaps = 4/227 (1%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT--LGD 87 +I G C H + VA + CGG L+N WV+TAAHC ++ + LG + + + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 88 RRAQRIKASKSFRHPGYSTQT-HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTV 146 Q + F P + D+ML+KL+ S + + LPS G+ C + Sbjct: 61 EDEQTRNPKEKFICPNKNNNEVLDKDIMLIKLDKPISNSKHIAPLSLPSSPPSVGSVCRI 120 Query: 147 SGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN-SMLCAGIPDSKKNACNGDS 205 GWG+ T TFP C ++ L+ C Y +LL LCAGI K+ C GDS Sbjct: 121 MGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQGGKDTCGGDS 180 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GGPL+C G QG+VS+G PCGQ PG+YT V +T WI + + Sbjct: 181 GGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGN 227 >4DGJ-A nrPDB Length = 235 Score = 265 bits (679), Expect = 9e-72, Method: Composition-based stats. Identities = 73/234 (31%), Positives = 119/234 (50%), Gaps = 18/234 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK------MNEYTVHLGSD 83 I+ G+ G+ PW V L ++L CG LV+ W+++AAHC +++T LG Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 84 ---TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 L + + +P Y+ + ND+ ++ L + + ++ + LP + Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPISLPEENQVF 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSK 197 PPG C+++GWGT T L DV L+S + C + + + +M+CAG + Sbjct: 121 PPGRNCSIAGWGTVVYQGTT-ADILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGG 179 Query: 198 KNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 ++C GDSGGPL+C R L G+ S+G + C PN PGVY +V +FT+WI Sbjct: 180 IDSCQGDSGGPLMCQENNRWFLAGVTSFG-YECALPNRPGVYARVSRFTEWIQS 232 >1IAU-A nrPDB Length = 227 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 80/231 (34%), Positives = 118/231 (51%), Gaps = 12/231 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQL---HCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ L+ +Q CGG L+ + +VLTAAHC + V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 142 ++ Q I + HP Y+ + ND+ML++L +A+ + V+ +RLPS PG Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQ 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPDSKKNAC 201 TC+V+GWG T L V + + + C + +++ LC G P+ KK + Sbjct: 121 TCSVAGWGQTAPLG-KHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSF 179 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPLVC QG+VS+G G P P T+V F WI TMK++ Sbjct: 180 KGDSGGPLVCNKVAQGIVSYGRNN-GMP--PRACTKVSSFVHWIKKTMKRY 227 >1P57-B nrPDB Length = 255 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 83/247 (33%), Positives = 116/247 (46%), Gaps = 26/247 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK------MNEYTVHLGSD 83 I+ G + G PWQV+L CGG L++ WVLTAAHC ++ + V G+ Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAV 60 Query: 84 TLGDRRAQRIKASKSFRHPGY------STQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC 137 ++ H GY +++ + ND+ LV L+S L+ ++ V LP+ Sbjct: 61 AQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAG 120 Query: 138 EP--PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLCAGI 193 + G CTV+GWG T L V +IS C Y + ++ M CAG Sbjct: 121 QALVDGKICTVTGWGNTQYYG-QQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGY 179 Query: 194 PDSKKNACNGDSGGPLVC--------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 P+ +AC GDSGGP VC R L G+VSWG C PGVYT+V F +WI Sbjct: 180 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYTKVSDFREWI 238 Query: 246 NDTMKKH 252 +K H Sbjct: 239 FQAIKTH 245 >3W94-A nrPDB Length = 235 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 72/237 (30%), Positives = 116/237 (48%), Gaps = 18/237 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE------YTVHLGSD 83 ++ G +G+ PW V+L + CG L+ W+LTAAHC + ++ LG Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 84 ---TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 ++ + Q + + + Y+ +T D+ ++ L + V V L S + Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPVCLASEDQHF 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIPDSK 197 P G C ++GWG + P L +V L+ +C ++ + +SMLCAG P+ Sbjct: 121 PAGRRCFIAGWGRDAEGG-SLPDILQEAEVPLVDQDECQRLLPEYTFTSSMLCAGYPEGG 179 Query: 198 KNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 ++C GDSGGPL+C R TL G+ S+G CG+P PG Y +V FT WI +T + Sbjct: 180 VDSCQGDSGGPLMCLEDARWTLIGVTSFGV-GCGRPERPGAYARVSAFTSWIAETRR 235 >1EKB-B nrPDB Length = 235 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 72/234 (30%), Positives = 117/234 (50%), Gaps = 18/234 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK------MNEYTVHLGSD 83 I+ G+ G+ PW VAL +Q CG LV+ W+++AAHC +++ LG Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 84 ---TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE-- 138 L + + + +P Y+ + ND+ ++ L + + ++ + LP + Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRKNNDIAMMHLEMKVNYTDYIQPICLPEENQVF 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSK 197 PPG C+++GWG T L DV L+S + C + + + +M+CAG Sbjct: 121 PPGRICSIAGWGALIYQGST-ADVLQEADVPLLSNEKCQQQMPEYNITENMVCAGYEAGG 179 Query: 198 KNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 ++C GDSGGPL+C R L G+ S+G + C PN PGVY +V +FT+WI Sbjct: 180 VDSCQGDSGGPLMCQENNRWLLAGVTSFG-YQCALPNRPGVYARVPRFTEWIQS 232 >3LC3-A nrPDB Length = 235 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 69/235 (29%), Positives = 109/235 (46%), Gaps = 16/235 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN--EYTVHLGSDTLG- 86 ++ G G PWQV L CGG +VNE+W++TAAHC + TV G + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 87 -DRRAQRIKASKSFRHPGYST--QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP--- 140 + Q+ + H Y+ + +D+ L++L+ L+S V + + + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEYTNIFL 120 Query: 141 -GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 + VSGWG + L + V L+ C + K + N+M CAG + ++ Sbjct: 121 KFGSGYVSGWGRVFHKGRS-ALVLQYLRVPLVDRATCLRSTKFTIYNNMFCAGFHEGGRD 179 Query: 200 ACNGDSGGPLV--CRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +C GDSGGP V GT L G++SWG C G+YT+V ++ WI + K Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAMKGKYGIYTKVSRYVNWIKEKTK 233 >2F83-A nrPDB Length = 625 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 72/234 (30%), Positives = 109/234 (46%), Gaps = 19/234 (8%) Query: 29 KIIDGAPCARGSHPWQVALLSGN---QLHCGGVLVNERWVLTAAHCKMNE-----YTVHL 80 +I+ G RG PWQV L + + + CGG ++ +W+LTAAHC V+ Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446 Query: 81 GSDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE 138 G + + H Y D+ L+KL + + + + LPS+ + Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICLPSKGD 506 Query: 139 PP--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIPD 195 T C V+GWG D + L + L++ ++C K Y+ + + M+CAG + Sbjct: 507 RNVIYTDCWVTGWGYRKLRD-KIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYRE 565 Query: 196 SKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 K+AC GDSGGPL C+ L G+ SWG C Q PGVYT V ++ WI Sbjct: 566 GGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 618 >3G01-A nrPDB Length = 227 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 81/230 (35%), Positives = 116/230 (50%), Gaps = 13/230 (5%) Query: 30 IIDGAPCARGSHPWQVAL----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 85 II G + S P+ + G ++ CGG LV +++VLTAAHCK TV LG+ + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 86 G--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 + Q I +K+ HP Y+ ND+ML+KL A+ + V+ + LP R PG Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPDDRSNDIMLLKLVRNAKRTRAVRPLNLPRRNAHVKPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLEN-SMLCAGIPDSKKNA 200 C V+GWG +PD FP L V + + Q C ++ + +C G K + Sbjct: 121 DECYVAGWGKV-TPDGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEICVGDSKIKGAS 179 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 GDSGGPLVC+ G+VS+G + P V+T+V F WI TMK Sbjct: 180 FRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTMK 226 >1X7A-C nrPDB Length = 235 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 71/235 (30%), Positives = 111/235 (47%), Gaps = 16/235 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN--EYTVHLGSDTLG- 86 I+ G G PWQV L CGG ++NE+WV+TAAHC + TV G Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 87 -DRRAQRIKASKSFRHPGYST--QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP--- 140 + QR ++ H Y+ + +D+ L++L+ L+S V + + + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATVNKYSHDIALLELDEPLTLNSYVTPICIADKEYTNIFL 120 Query: 141 -GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 + VSGWG + + + L + V L+ C + K + ++M CAG + K+ Sbjct: 121 KFGSGYVSGWGRVFNRGRS-ATILQYLKVPLVDRATCLRSTKFTIYSNMFCAGFHEGGKD 179 Query: 200 ACNGDSGGPLV--CRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +C GDSGGP V GT L G++SWG C G+YT+V ++ WI + K Sbjct: 180 SCQGDSGGPHVTEVEGTSFLTGIISWGEE-CAVKGKYGIYTKVSRYVNWIKEKTK 233 >1KIG-H nrPDB Length = 241 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 75/236 (31%), Positives = 110/236 (46%), Gaps = 16/236 (6%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCKM--NEYTVHLGSDTLG 86 I+ G CA G PWQ L++ N+ CGG ++NE +VLTAAHC +TV +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 87 DRRAQRI--KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGT-- 142 + + + +H + +T+ D+ +++L + R V LP + T Sbjct: 61 QEEGNEMAHEVEMTVKHSRFVKETYDFDIAVLRLKTPIRFRRNVAPACLPEKDWAEATLM 120 Query: 143 ---TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 T VSG+G T S L ++V + C + +M CAG ++ Sbjct: 121 TQKTGIVSGFGRTHEKG-RLSSTLKMLEVPYVDRSTCKLSSSFTITPNMFCAGYDTQPED 179 Query: 200 ACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 AC GDSGGP V R + G+VSWG C + GVYT+V F KWI+ MK Sbjct: 180 ACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKFGVYTKVSNFLKWIDKIMKA 234 >3K65-B nrPDB Length = 308 Score = 258 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 82/265 (30%), Positives = 119/265 (44%), Gaps = 36/265 (13%) Query: 23 EEAQGDKIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM------- 73 E +I++G+ G PWQV L S +L CG L+++RWVLTAAHC + Sbjct: 43 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 102 Query: 74 ---NEYTVHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSS 126 N+ V +G T +R ++I K + HP Y+ + D+ L+KL S Sbjct: 103 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSD 162 Query: 127 MVKKVRLPSRC-----EPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDC 176 + V LP R G V+GWG T + PS L V++ ++ C Sbjct: 163 YIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVC 222 Query: 177 TKVYKDLLENSMLCAGI-PDSKK--NACNGDSGGPLVC------RGTLQGLVSWGTFPCG 227 + + ++M CAG PD K +AC GD+GGP V R G+VSWG C Sbjct: 223 KDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGE-GCD 281 Query: 228 QPNDPGVYTQVCKFTKWINDTMKKH 252 + G YT V + KWI + + Sbjct: 282 RDGKYGFYTHVFRLKKWIQKVIDQF 306 >5UGG-A nrPDB Length = 251 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 79/247 (31%), Positives = 117/247 (47%), Gaps = 25/247 (10%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHC-----KMNE 75 + +++ G S PWQV+L + CGG L++ WVLTAAHC + + Sbjct: 14 EPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSS 73 Query: 76 YTVHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRL 133 Y V LG+ + Q I+ S+ F P D+ L+KL+S A ++ V L Sbjct: 74 YKVILGAHQEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLSSPAVITDKVIPACL 127 Query: 134 PSRCE--PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSML 189 PS T C ++GWG T L + +I + C + ++++ L Sbjct: 128 PSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTEL 185 Query: 190 CAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 CAG ++C GDSGGPLVC + LQG+ SWG C +PN PGVY +V +F WI Sbjct: 186 CAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRFVTWI 244 Query: 246 NDTMKKH 252 M+ + Sbjct: 245 EGVMRNN 251 >3NXP-A nrPDB Length = 424 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 83/265 (31%), Positives = 119/265 (44%), Gaps = 36/265 (13%) Query: 23 EEAQGDKIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM------- 73 E +I++G+ G PWQV L S +L CG L+++RWVLTAAHC + Sbjct: 159 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 218 Query: 74 ---NEYTVHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSS 126 N+ V +G T +R ++I K + HP Y+ + D+ L+KL S Sbjct: 219 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSD 278 Query: 127 MVKKVRLPSRC-----EPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDC 176 + V LP R G V+GWG T + PS L V++ ++ C Sbjct: 279 YIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVC 338 Query: 177 TKVYKDLLENSMLCAGI-PDSKK--NACNGDSGGPLVC------RGTLQGLVSWGTFPCG 227 + + ++M CAG PD K +AC GDSGGP V R G+VSWG C Sbjct: 339 KDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCD 397 Query: 228 QPNDPGVYTQVCKFTKWINDTMKKH 252 + G YT V + KWI + + Sbjct: 398 RDGKYGFYTHVFRLKKWIQKVIDQF 422 >1MKW-K nrPDB Length = 308 Score = 257 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 82/265 (30%), Positives = 119/265 (44%), Gaps = 36/265 (13%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM------ 73 E +I++G G PWQV L S +L CG L+++RWVLTAAHC + Sbjct: 42 FESYIEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDK 101 Query: 74 ----NEYTVHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLS 125 ++ V +G T +R+ ++I K + HP Y+ + D+ L+KL LS Sbjct: 102 NFTVDDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELS 161 Query: 126 SMVKKVRLPSRCEPP-----GTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQD 175 + V LP + G V+GWG TTS PS L V++ L+ Sbjct: 162 DYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPV 221 Query: 176 CTKVYKDLLENSMLCAGI---PDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPC 226 C + + ++M CAG + +AC GDSGGP V R G+VSWG C Sbjct: 222 CKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE-GC 280 Query: 227 GQPNDPGVYTQVCKFTKWINDTMKK 251 + G YT V + KWI + + Sbjct: 281 DRDGKYGFYTHVFRLKKWIQKVIDR 305 >4DUR-A nrPDB Length = 791 Score = 257 bits (657), Expect = 3e-69, Method: Composition-based stats. Identities = 79/247 (31%), Positives = 117/247 (47%), Gaps = 25/247 (10%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHC-----KMNE 75 + +++ G S PWQV+L + CGG L++ WVLTAAHC + + Sbjct: 554 EPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSS 613 Query: 76 YTVHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRL 133 Y V LG+ + Q I+ S+ F P D+ L+KL+S A ++ V L Sbjct: 614 YKVILGAHQEVNLEPHVQEIEVSRLFLEPTRK------DIALLKLSSPAVITDKVIPACL 667 Query: 134 PSRCE--PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSML 189 PS T C ++GWG T L + +I + C + ++++ L Sbjct: 668 PSPNYVVADRTECFITGWGETQ--GTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTEL 725 Query: 190 CAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 CAG ++C GDSGGPLVC + LQG+ SWG C +PN PGVY +V +F WI Sbjct: 726 CAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRFVTWI 784 Query: 246 NDTMKKH 252 M+ + Sbjct: 785 EGVMRNN 791 >3DFJ-A nrPDB Length = 263 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 83/244 (34%), Positives = 115/244 (47%), Gaps = 23/244 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE-----YTVHLGSDT 84 I G+ G PWQV++ CGG LV+E+WVL+AAHC +E Y V LG+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 L--GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PP 140 L A+ HP Y + D+ L++L+ S ++ + LP+ P Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAANASFPN 120 Query: 141 GTTCTVSGWGTTTSPDVTF-PSDLMCVDVKLISPQDCTKVY--------KDLLENSMLCA 191 G CTV+GWG P L ++V LIS + C +Y ++ M+CA Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEEPHFVQEDMVCA 180 Query: 192 GIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 G + K+AC GDSGGPL C L G+VSWG CG N PGVYT + WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWIQS 239 Query: 248 TMKK 251 + + Sbjct: 240 KVTE 243 >3E0N-B nrPDB Length = 271 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 83/244 (34%), Positives = 114/244 (46%), Gaps = 23/244 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE-----YTVHLGSDT 84 I G+ G PWQV++ CGG LV+E+WVL+AAHC +E Y V LG+ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 85 L--GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEPP 140 L A+ HP Y + D+ L++L+ S ++ + LP P Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPISLPAAQASFPN 120 Query: 141 GTTCTVSGWGTTTSPDVTF-PSDLMCVDVKLISPQDCTKVY--------KDLLENSMLCA 191 G CTV+GWG P L ++V LIS + C +Y ++ M+CA Sbjct: 121 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEEPHFVQEDMVCA 180 Query: 192 GIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 G + K+AC GDSGGPL C L G+VSWG CG N PGVYT + WI Sbjct: 181 GYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYTLASSYASWIQS 239 Query: 248 TMKK 251 + + Sbjct: 240 KVTE 243 >4NZQ-A nrPDB Length = 557 Score = 256 bits (655), Expect = 6e-69, Method: Composition-based stats. Identities = 83/265 (31%), Positives = 119/265 (44%), Gaps = 36/265 (13%) Query: 23 EEAQGDKIIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM------- 73 E +I++G+ G PWQV L S +L CG L+++RWVLTAAHC + Sbjct: 292 ESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKN 351 Query: 74 ---NEYTVHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSS 126 N+ V +G T +R ++I K + HP Y+ + D+ L+KL S Sbjct: 352 FTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSD 411 Query: 127 MVKKVRLPSRC-----EPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDC 176 + V LP R G V+GWG T + PS L V++ ++ C Sbjct: 412 YIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVC 471 Query: 177 TKVYKDLLENSMLCAGI-PDSKK--NACNGDSGGPLVC------RGTLQGLVSWGTFPCG 227 + + ++M CAG PD K +AC GDSGGP V R G+VSWG C Sbjct: 472 KDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCD 530 Query: 228 QPNDPGVYTQVCKFTKWINDTMKKH 252 + G YT V + KWI + + Sbjct: 531 RDGKYGFYTHVFRLKKWIQKVIDQF 555 >3TK9-A nrPDB Length = 226 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 76/230 (33%), Positives = 119/230 (51%), Gaps = 13/230 (5%) Query: 30 IIDGAPCARGSHPWQVA---LLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ L ++ CGG+LV + +VLTAAHC+ + V LG+ + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGT 142 ++ Q I + HP Y+ + N++ML++L +A+ ++ V+ +RLPS PG Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPKNFSNNIMLLQLERKAKWTTAVRPLRLPSSKAQVKPGQ 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK-VYKDLLENSMLCAGIPDSKKNAC 201 C+V+GWG + T + L V + + C + + + + +C G P + Sbjct: 121 LCSVAGWGYVSMS--TLATTLQEVLLTVQKDCQCERLFHGNYSRATEICVGDPKKTQTGF 178 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 GDSGGPLVC+ QG++S+G G P PGVY +V F WI TMK+ Sbjct: 179 KGDSGGPLVCKDVAQGILSYGNKK-GTP--PGVYIKVSHFLPWIKRTMKR 225 >1BRU-P nrPDB Length = 241 Score = 256 bits (654), Expect = 8e-69, Method: Composition-based stats. Identities = 76/243 (31%), Positives = 124/243 (51%), Gaps = 22/243 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGN----QLHCGGVLVNERWVLTAAHCKMNE--YTVHLGSD 83 ++ G S PWQV+L + + CGG LV++ WVLTAAHC + Y V LG Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 84 TL--GDRRAQRIKASKSFRHPGYSTQ--THVNDLMLVKLNSQARLSSMVKKVRLPSRC-- 137 +L + + +K SK H +++ ++ ND+ L+KL S L+ ++ LP+ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTI 120 Query: 138 EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAGIPD 195 P C V+GWG + + P L + ++ C+K + ++ +M+CAG D Sbjct: 121 LPNNYVCYVTGWGRLQTNGAS-PDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAG-GD 178 Query: 196 SKKNACNGDSGGPLVCRG-----TLQGLVSWGT-FPCGQPNDPGVYTQVCKFTKWINDTM 249 ++CNGDSGGPL C+G + G+VS+G+ C + P V+T+V + WIN + Sbjct: 179 GIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVI 238 Query: 250 KKH 252 + Sbjct: 239 ANN 241 >2F91-A nrPDB Length = 237 Score = 252 bits (645), Expect = 8e-68, Method: Composition-based stats. Identities = 76/235 (32%), Positives = 110/235 (46%), Gaps = 20/235 (8%) Query: 30 IIDGAPCARGSHPWQVALLSG----NQLHCGGVLVNERWVLTAAHCKMNE-------YTV 78 I+ G G P+Q++ + CG + NE + +TA HC + + Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 79 HLGSDT--LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR 136 G + + Q I SK H + ND+ L+KL+ + V + LP + Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQ 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYK-DLLENSMLCAGIPD 195 V+GWGTT+ T P L V V L+S +DC Y D + +SM+CAG+P+ Sbjct: 121 GHTATGDVIVTGWGTTSEGGNT-PDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVPE 179 Query: 196 SKKNACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 K++C GDSGGPL T L G+VSWG + C +P PGVYT+V WI Sbjct: 180 GGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSYHVDWIK 233 >2OCV-B nrPDB Length = 259 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 116/258 (44%), Gaps = 36/258 (13%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G +G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 78 VHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVKKVRL 133 V +G T +R ++I K + HP Y+ + D+ L+KL S + V L Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCL 120 Query: 134 PSR-----CEPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183 P + G V+GWG TT+ + PS L V++ ++ C + Sbjct: 121 PDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIR 180 Query: 184 LENSMLCAGI---PDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGV 234 + ++M CAG + +AC GDSGGP V R G+VSWG C + G Sbjct: 181 ITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRKGKYGF 239 Query: 235 YTQVCKFTKWINDTMKKH 252 YT V + WI + + Sbjct: 240 YTHVFRLKAWIQKVIDQF 257 >1FDP-A nrPDB Length = 235 Score = 252 bits (643), Expect = 1e-67, Method: Composition-based stats. Identities = 72/235 (30%), Positives = 117/235 (49%), Gaps = 17/235 (7%) Query: 28 DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN----EYTVHLGSD 83 +I+ G + P+ ++ CGGVLV E+WVL+AAHC + + V LG+ Sbjct: 6 GRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAH 65 Query: 84 TLGDRRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP----SRC 137 +L + ++ HP T +DL+L++L+ +A L V+ LP R Sbjct: 66 SLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRP--LPWQRVDRD 123 Query: 138 EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAGIPD 195 PGT C V+GWG P L V + ++ C + + + ++CA Sbjct: 124 VAPGTLCDVAGWGIVNHAGRR-PDSLQHVLLPVLDRATCNRRTHHDGAITERLMCA--ES 180 Query: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +++++C GDSGGPLVC G L+G+V+ G+ CG PG+YT+V + WI+ + Sbjct: 181 NRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA 235 >4Z6A-H nrPDB Length = 249 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 76/238 (31%), Positives = 106/238 (44%), Gaps = 18/238 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKM-----NEYTVHLGSDT 84 I+ G C +G PWQV LL CGG L+N WV++AAHC LG Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 85 LGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGT 142 L + Q + ++ Y T +D+ L++L+ L+ V + LP R T Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERT 120 Query: 143 TC-----TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSK 197 VSGWG T +LM ++V + QDC Y + M CAG D Sbjct: 121 LAFVRFSLVSGWGQLLDRGAT-ALELMVLNVPRLMTQDCEASYPGKITEYMFCAGYSDGS 179 Query: 198 KNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 K++C GDSGGP L G+VSWG C GVYT+V ++ +W+ M+ Sbjct: 180 KDSCKGDSGGPHATHYRGTWYLTGIVSWG-QGCATVGHFGVYTRVSQYIEWLQKLMRS 236 >1C5M-D nrPDB Length = 255 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 69/236 (29%), Positives = 109/236 (46%), Gaps = 16/236 (6%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCKM--NEYTVHLGSDTLG 86 I+ G C G PWQ L++ N+ CGG +++E ++LTAAHC + V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 87 DRR--AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGT-- 142 + +H ++ +T+ D+ +++L + V LP R T Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLM 120 Query: 143 ---TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199 T VSG+G T + L ++V + C ++ +M CAG +++ Sbjct: 121 TQKTGIVSGFGRTHEKG-RQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQED 179 Query: 200 ACNGDSGGPLVCRGT----LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 AC GDSGGP V R + G+VSWG C + G+YT+V F KWI+ +MK Sbjct: 180 ACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKYGIYTKVTAFLKWIDRSMKT 234 >3P8G-A nrPDB Length = 241 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 74/240 (30%), Positives = 110/240 (45%), Gaps = 23/240 (9%) Query: 30 IIDGAPCARGSHPWQVALLS-GNQLHCGGVLVNERWVLTAAHCKMNE----------YTV 78 ++ G G PWQV+L + G CG L++ W+++AAHC +++ +T Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 79 HLGSDTLGDRRA---QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP- 134 LG R A Q + + HP ++ T D+ L++L A SSMV+ + LP Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKPAEYSSMVRPICLPD 120 Query: 135 -SRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI 193 S P G V+GWG T L ++++I C + + M+C G Sbjct: 121 ASHVFPAGKAIWVTGWGHTQYGGTG-ALILQKGEIRVIQQTTCENLLPQQITPRMMCVGF 179 Query: 194 PDSKKNACNGDSGGPLVC-----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 ++C GDSGGPL R G+VSWG C Q N PGVYT++ F WI + Sbjct: 180 LSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD-GCAQRNKPGVYTRLPLFRDWIKEN 238 >6AOD-C nrPDB Length = 245 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 71/233 (30%), Positives = 109/233 (46%), Gaps = 19/233 (8%) Query: 30 IIDGAPCARGSHPWQVALLSGN---QLHCGGVLVNERWVLTAAHCKMNE-----YTVHLG 81 I+ G RG PWQV L + + + CGG ++ +W+LTAAHC V+ G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 82 SDTLGD--RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139 + + H Y D+ L+KL + + + + + LPS+ + Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPISLPSKGDR 120 Query: 140 P--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-LLENSMLCAGIPDS 196 T C V+GWG D + L + L++ ++C K Y+ + + M+CAG + Sbjct: 121 NVIYTDCWVTGWGYRKLRD-KIQNTLQKAKIPLVTNEECQKRYRGHKITHKMICAGYREG 179 Query: 197 KKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 K+AC GD+GGPL C+ L G+ SWG C Q PGVYT V ++ WI Sbjct: 180 GKDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDWI 231 >4MPW-A nrPDB Length = 245 Score = 250 bits (640), Expect = 3e-67, Method: Composition-based stats. Identities = 83/242 (34%), Positives = 116/242 (47%), Gaps = 29/242 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGN---QLHCGGVLVNERWVLTAAHCKMNE------YTVHL 80 I+ G R PWQV+L CGG L++ +WVLTAAHC + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 81 GSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCE 138 L + Q + S+ HP + T D+ L++L ++SS V V LP S Sbjct: 61 REQHLY-YQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETF 119 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSD-LMCVDVKLISPQDCTKVYK---------DLLENSM 188 PPG C V+GWG + + P L V V ++ C Y ++ + M Sbjct: 120 PPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDM 179 Query: 189 LCAGIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKW 244 LCAG ++++C GDSGGPLVC+ G+VSWG C QPN PG+YT+V + W Sbjct: 180 LCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGIYTRVTYYLDW 236 Query: 245 IN 246 I+ Sbjct: 237 IH 238 >1BDA-A nrPDB Length = 265 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 86/253 (33%), Positives = 124/253 (49%), Gaps = 32/253 (12%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQ------LHCGGVLVNERWVLTAAHCKM-----NEYT 77 +I G SHPWQ A+ + ++ CGG+L++ W+L+AAHC + T Sbjct: 13 RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLT 72 Query: 78 VHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQ----ARLSSMVKKV 131 V LG + Q+ + K H + T+ ND+ L++L S A+ SS+V+ V Sbjct: 73 VILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTV 132 Query: 132 RLPSRCE--PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY--KDLLENS 187 LP P T C +SG+G + + L V+L CT + + ++ Sbjct: 133 CLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDN 192 Query: 188 MLCAGIPDSK------KNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQ 237 MLCAG S +AC GDSGGPLVC R TL G++SWG CGQ + PGVYT+ Sbjct: 193 MLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWG-LGCGQKDVPGVYTK 251 Query: 238 VCKFTKWINDTMK 250 V + WI D M+ Sbjct: 252 VTNYLDWIRDNMR 264 >4H4F-A nrPDB Length = 249 Score = 250 bits (639), Expect = 4e-67, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 110/240 (45%), Gaps = 21/240 (8%) Query: 30 IIDGAPCARGSHPWQVALLSGN----QLHCGGVLVNERWVLTAAHCKMNE--YTVHLGSD 83 ++ G S PWQ++L + CGG L+ +VLTAAHC N Y V +G + Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 84 TL---GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC--E 138 L + + + H ++ ND+ L+KL LS ++ LP + Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLL 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAGIPDS 196 P C V+GWG + L ++ C++ + ++ +M+CAG D Sbjct: 121 PKDYPCYVTGWGRLWTNGP-IADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG-GDG 178 Query: 197 KKNACNGDSGGPLVCR-----GTLQGLVSWGT-FPCGQPNDPGVYTQVCKFTKWINDTMK 250 +ACNGDSGGPL C+ + G+VS+G+ C P VYT+V + WIN+ M+ Sbjct: 179 VISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 238 >1ETT-H nrPDB Length = 259 Score = 249 bits (636), Expect = 9e-67, Method: Composition-based stats. Identities = 81/257 (31%), Positives = 117/257 (45%), Gaps = 36/257 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G G PWQV L S +L CG L+++RWVLTAAHC + ++ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVKKVRL 133 V +G T +R+ ++I K + HP Y+ + D+ L+KL LS + V L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 134 PSRCEPP-----GTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183 P + G V+GWG TTS PS L V++ L+ C + Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVERPVCKASTRIR 180 Query: 184 LENSMLCAGI---PDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGV 234 + ++M CAG + +AC GDSGGP V R G+VSWG C + G Sbjct: 181 ITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE-GCDRDGKYGF 239 Query: 235 YTQVCKFTKWINDTMKK 251 YT V + KWI + + Sbjct: 240 YTHVFRLKKWIQKVIDR 256 >5XRF-A nrPDB Length = 242 Score = 248 bits (635), Expect = 1e-66, Method: Composition-based stats. Identities = 72/233 (30%), Positives = 111/233 (47%), Gaps = 6/233 (2%) Query: 24 EAQGDKIIDGAPCARGSHPWQVALLSGN--QLHCGGVLVNERWVLTAAHCKMNEYTVHLG 81 + + +I G C H + A + C G L++E WVL AAHC ++LG Sbjct: 1 QKSSELVIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLG 60 Query: 82 SDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE 138 D +R + + D++L+KLN S+ + + LPS Sbjct: 61 MHNQSIQFDDEQRRYAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLPSSPP 120 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL-ENSMLCAGIPDSK 197 G+ C V GWG +S P C ++ L++ +C Y D+ +LCAG+ + Sbjct: 121 SIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGVLEGG 180 Query: 198 KNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 + CN DSGGPL+C G QG+V +G +PC QPN PG+YT+V + WI + + Sbjct: 181 IDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIA 233 >1LTO-A nrPDB Length = 245 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 81/242 (33%), Positives = 115/242 (47%), Gaps = 29/242 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ---LHCGGVLVNERWVLTAAHC------KMNEYTVHL 80 I+ G R PWQV+L ++ CGG L++ +WVLTAAHC + V L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 81 GSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCE 138 L + Q + S+ HP + D+ L++L +SS V V LP S Sbjct: 61 REQHLY-YQDQLLPVSRIIVHPQFYIIQTGADIALLELEEPVNISSRVHTVMLPPASETF 119 Query: 139 PPGTTCTVSGWGTTTSPDVTFPSD-LMCVDVKLISPQDCTKVYK---------DLLENSM 188 PPG C V+GWG + + P L V V ++ C Y ++ + M Sbjct: 120 PPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIIRDDM 179 Query: 189 LCAGIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKW 244 LCAG ++++C GDSGGPLVC+ G+VSW C QPN PG+YT+V + W Sbjct: 180 LCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNRPGIYTRVTYYLDW 236 Query: 245 IN 246 I+ Sbjct: 237 IH 238 >1VR1-H nrPDB Length = 261 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 79/262 (30%), Positives = 116/262 (44%), Gaps = 40/262 (15%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ------LHCGGVLVNERWVLTAAHCKM---------- 73 I++G+ G PWQV L + ++ CG L+++RWVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 74 NEYTVHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVK 129 N+ V +G T +R ++I K + HP Y+ + D+ L+KL S + Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIH 120 Query: 130 KVRLPSRC-----EPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKV 179 V LP R G V+GWG T + PS L V++ ++ C Sbjct: 121 PVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDS 180 Query: 180 YKDLLENSMLCAGI-PDSKK--NACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPN 230 + + ++M CA PD K +AC GDSGGP V R G+VSWG C + Sbjct: 181 TRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE-GCDRDG 239 Query: 231 DPGVYTQVCKFTKWINDTMKKH 252 G YT V + KWI + + Sbjct: 240 KYGFYTHVFRLKKWIQKVIDQF 261 >1SC8-U nrPDB Length = 262 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 88/249 (35%), Positives = 125/249 (50%), Gaps = 27/249 (10%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQ-----LHCGGVLVNERWVLTAAHCKMN-----EYTV 78 KII G + PW A+ ++ CGG L++ WV++A HC ++ +Y V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 79 HLGSDTLGDRR--AQRIKASKSFRHPGYSTQT--HVNDLMLVKLNSQ----ARLSSMVKK 130 +LG L + + H YS T H ND+ L+K+ S+ A+ S ++ Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQT 134 Query: 131 VRLPSRCEPP--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLEN 186 + LPS P GT+C ++G+G S D +P L VKLIS ++C + Y + Sbjct: 135 ISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTT 194 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242 MLCA P K ++C GDSGGPLVC R TL G+VSWG C + PGVYT+V F Sbjct: 195 KMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGR-GCALKDKPGVYTRVSHFL 253 Query: 243 KWINDTMKK 251 WI K+ Sbjct: 254 PWIRSHTKE 262 >1MZD-A nrPDB Length = 240 Score = 247 bits (630), Expect = 5e-66, Method: Composition-based stats. Identities = 80/234 (34%), Positives = 119/234 (50%), Gaps = 14/234 (5%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSD 83 +II G + S P+ ++ G CGGVL++ +WVLTAAHC K TV LG+ Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAH 61 Query: 84 TLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-CEPP 140 +L A Q ++ K ++ ND+MLVKL + A+L+ VK + + S+ Sbjct: 62 SLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRS 121 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKD--LLENSMLCAGIPDS 196 GT C V+GWG T + L V V ++S + C Y + M+CAG Sbjct: 122 GTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKG 181 Query: 197 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVC-KFTKWINDTM 249 +K++C GD+GGPL+C+G +VS G CG PG+YT + K+ WI + Sbjct: 182 QKDSCKGDAGGPLICKGVFHAIVS-GGHECGVATKPGIYTLLTKKYQTWIKSNL 234 >1KYN-A nrPDB Length = 235 Score = 246 bits (629), Expect = 6e-66, Method: Composition-based stats. Identities = 81/231 (35%), Positives = 115/231 (49%), Gaps = 12/231 (5%) Query: 30 IIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG 86 II G S P+ L Q CGG LV E +VLTAAHC + V LG+ + Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 87 --DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS--RCEPPGT 142 + Q I A ++ RHP Y+ +T ND+ML++L+ + R + V V LP PGT Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGT 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACN 202 CTV+GWG + T L V +++ + C +++ +C G +K A Sbjct: 121 LCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFK 178 Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GDSGGPL+C G+VS+G G P P V+T+V F WI TM+ + Sbjct: 179 GDSGGPLLCNNVAHGIVSYGKSS-GVP--PEVFTRVSSFLPWIRTTMRSFK 226 >1PYT-D nrPDB Length = 251 Score = 246 bits (628), Expect = 9e-66, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 114/250 (45%), Gaps = 20/250 (8%) Query: 19 ETAGEEAQGDKIIDGAPCARGSHPWQVALLSGN----QLHCGGVLVNERWVLTAAHCKMN 74 + +++ G S PWQ++L + CGG L+ VLTAAHC N Sbjct: 3 APIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISN 62 Query: 75 E--YTVHLGSDTL---GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK 129 Y V LG + L + + + F H +++ ND+ L+KL L ++ Sbjct: 63 TLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVRNDIALIKLAETVELGDTIQ 122 Query: 130 KVRLPSRC--EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLE 185 LPS P C V+GWG + ++L ++ C++ + ++ Sbjct: 123 VACLPSEGSLLPQDYPCFVTGWGRLYTNGP-IAAELQQGLQPVVDYATCSQRDWWGTTVK 181 Query: 186 NSMLCAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTF-PCGQPNDPGVYTQVCK 240 +M+CAG D +ACNGDSGGPL C + ++G+VS+G+ C P V+T+V Sbjct: 182 ETMVCAG-GDGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTVFTRVSA 240 Query: 241 FTKWINDTMK 250 + WIN ++ Sbjct: 241 YIDWINQKLQ 250 >3F6U-H nrPDB Length = 240 Score = 246 bits (628), Expect = 9e-66, Method: Composition-based stats. Identities = 84/239 (35%), Positives = 122/239 (51%), Gaps = 20/239 (8%) Query: 31 IDGAPCARGSHPWQVALL-SGNQLHCGGVLVNERWVLTAAHCK--MNEYTVHLGSDTLG- 86 IDG RG PWQV LL S +L CG VL++ WVLTAAHC + V LG L Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRR 61 Query: 87 -DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP------ 139 ++ + + F HP YS T ND+ L+ L A LS + + LP Sbjct: 62 WEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQ 121 Query: 140 PGTTCTVSGWGTTTSPD----VTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195 G V+GWG +S + L + + ++ +C++V +++ +MLCAGI Sbjct: 122 AGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILG 181 Query: 196 SKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 +++AC GDSGGP+V L GLVSWG CG ++ GVYT+V ++ WI+ ++ Sbjct: 182 DRQDACEGDSGGPMVASFHGTWFLVGLVSWGE-GCGLLHNYGVYTKVSRYLDWIHGHIR 239 >4Q7Y-A nrPDB Length = 250 Score = 245 bits (627), Expect = 9e-66, Method: Composition-based stats. Identities = 88/232 (37%), Positives = 117/232 (50%), Gaps = 11/232 (4%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYT----VHLGSDTL 85 II G S P+ ++ G Q HCGG L+ RWV++AAHC + V LG+ L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 86 G--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP---SRCEPP 140 + Q HP Y TH ND+ L++LN A L V +RLP +R Sbjct: 61 STAEPTQQVFGIDALTTHPDYHPMTHANDICLLRLNGSAVLGPAVGLLRLPGRRARPPTA 120 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS-KKN 199 GT C V+GWG + + P LM V+++ P C +K L +MLC DS ++ Sbjct: 121 GTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTMLCTRSGDSHRRG 179 Query: 200 ACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 C+ DSGGPLVCR GLVS+ CG P P VYTQV F WI D +++ Sbjct: 180 FCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDVVRR 231 >2OQ5-A nrPDB Length = 232 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 74/230 (32%), Positives = 103/230 (44%), Gaps = 14/230 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--- 86 I+ G G PWQ +L CG L+N W+++AAHC + + G Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEPPGTTC 144 + + H Y +H D+ L +L+S ++ V +V LP S PG Sbjct: 61 KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVM 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAGIPDSKKNACN 202 V+G+G + + + L V LI C + Y D + MLCAG + K +AC Sbjct: 121 FVTGFGALKNDGYS-QNHLRQAQVTLIDATTCNEPQAYNDAITPRMLCAGSLEGKTDACQ 179 Query: 203 GDSGGPLVCR-----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247 GDSGGPLV L G+VSWG C +PN PGVYT+V WI Sbjct: 180 GDSGGPLVSSDARDIWYLAGIVSWGDE-CAKPNKPGVYTRVTALRDWITS 228 >5FCR-A nrPDB Length = 234 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 71/234 (30%), Positives = 114/234 (48%), Gaps = 14/234 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC-----KMNEYTVHLGSDT 84 I+ G A + P+ ++ CGG L++E+WVL+AAHC + V LG+ + Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 85 LGDRRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRL--PSRCEPP 140 L + HPG + +DL+L KL+ A L V+ + L + P Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP 120 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAGIPDSKK 198 GT C V+GWG T P L + V +++ C + ++ +M+CA +++ Sbjct: 121 GTLCDVAGWGVVTHAGRR-PDVLHQLRVSIMNRTTCNLRTYHDGVVTINMMCA--ESNRR 177 Query: 199 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 + C GDSG PLVC ++G+V+WG+ CG PGVYT+V + WI + + Sbjct: 178 DTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENITNGN 231 >1Q3X-A nrPDB Length = 328 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 80/266 (30%), Positives = 121/266 (45%), Gaps = 32/266 (12%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP+ + L+ T G +I G G PWQV +L G G L+ + WVL Sbjct: 69 LPVCEPVCGLSARTTG-----GRIYGGQKAKPGDFPWQVLILGGT--TAAGALLYDNWVL 121 Query: 67 TAAHC------KMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQT-HVNDLMLVKLN 119 TAAH + + +G+ + + F H GY+ ND+ L+KLN Sbjct: 122 TAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLN 181 Query: 120 SQARLSSMVKKVRLPSRCEPP----GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175 ++ ++S + + LP + T SGWG T +LM VD+ ++ Q Sbjct: 182 NKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQK 239 Query: 176 CTKVY------KDLLENSMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSWGT 223 CT Y + + +MLCAG+ K++C GDSGG LV R + G+VSWG+ Sbjct: 240 CTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGS 299 Query: 224 FPCGQPNDPGVYTQVCKFTKWINDTM 249 CG+ GVYT+V + WI + + Sbjct: 300 MNCGEAGQYGVYTKVINYIPWIENII 325 >1AZZ-A nrPDB Length = 226 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 69/221 (31%), Positives = 104/221 (47%), Gaps = 6/221 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE--YTVHLGSDTLGD 87 I+ G S P Q AL + CGG L++ W+LTAAHC V LG+ + + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 88 RRAQR--IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCT 145 A + I+++ H Y++ ND+ +++L L++ + V LPS GT T Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVISNDIAVIRLPVPVTLTAAIATVGLPSTDVGVGTVVT 120 Query: 146 VSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDS 205 +GWG + + L VDV ++S DC VY ++ + +C K CNGDS Sbjct: 121 PTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICI-DSTGGKGTCNGDS 178 Query: 206 GGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 GGPL G G+ S+G + P +T+V F WI Sbjct: 179 GGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >1FUJ-A nrPDB Length = 221 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 67/232 (28%), Positives = 110/232 (47%), Gaps = 22/232 (9%) Query: 30 IIDGAPCARGSHPWQVALL---SGNQLHCGGVLVNERWVLTAAHCKMN----EYTVHLGS 82 I+ G S P+ +L + CGG L++ +VLTAAHC + V LG+ Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 83 DTL--GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP 140 + + Q ++ F + Y + +ND++L++L+S A LS+ V V+LP + +P Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYDAENKLNDILLIQLSSPANLSASVATVQLPQQDQPV 119 Query: 141 --GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKK 198 GT C GWG + D L ++V +++ +C +P K Sbjct: 120 PHGTQCLAMGWGRVGAHDPPAQ-VLQELNVTVVT---------FFCRPHNICTFVPRRKA 169 Query: 199 NACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 C GDSGGPL+C G +QG+ S+ + C P +T+V + WI T++ Sbjct: 170 GICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRSTLR 221 >3RP2-A nrPDB Length = 224 Score = 243 bits (622), Expect = 4e-65, Method: Composition-based stats. Identities = 79/228 (34%), Positives = 120/228 (52%), Gaps = 13/228 (5%) Query: 30 IIDGAPCARGSHPWQVAL----LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL 85 II G S P+ L G ++ CGG L++ ++VLTAAHCK E TV LG+ + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 86 --GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPG 141 + Q+IK K H Y++ +++D+ML+KL + L+ V V LPS + PG Sbjct: 61 RKRESTQQKIKVEKQIIHESYNSVPNLHDIMLLKLEKKVELTPAVNVVPLPSPSDFIHPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 C +GWG T D T L V+++++ + C Y+ +C G P + + A Sbjct: 121 AMCWAAGWGKTGVRDPT-SYTLREVELRIMDEKACVD-YRYYEYKFQVCVGSPTTLRAAF 178 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GDSGGPL+C G G+VS+G P +P P ++T+V + WIN + Sbjct: 179 MGDSGGPLLCAGVAHGIVSYG-HPDAKP--PAIFTRVSTYVPWINAVI 223 >1FIZ-A nrPDB Length = 263 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 69/252 (27%), Positives = 104/252 (41%), Gaps = 30/252 (11%) Query: 30 IIDGAPCARGSHPWQVALL------SGNQLHCGGVLVNERWVLTAAHCKMN-----EYTV 78 ++ G G+ PW V+L + CGG+L+N WVLTAAHC N ++ + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 79 HLGSDTLG-------DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKV 131 G++ + Q + H Y + +ND+ L+K+ + Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEINDIALIKITPPVPCGPFIGPG 120 Query: 132 RLPS---RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLEN 186 LP TC V+GWG L V LI + C + Y + + Sbjct: 121 CLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCNSTRWYNGRIRS 180 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCRG------TLQGLVSWGTFPCGQPNDPGVYTQVCK 240 + +CAG P K + C GDSGGPL+CR + G+ SWG C + PGVYT Sbjct: 181 TNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWGV-GCARAKRPGVYTSTWP 239 Query: 241 FTKWINDTMKKH 252 + WI + + Sbjct: 240 YLNWIASKIGSN 251 >1ORF-A nrPDB Length = 234 Score = 243 bits (620), Expect = 6e-65, Method: Composition-based stats. Identities = 78/232 (33%), Positives = 120/232 (51%), Gaps = 12/232 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN-EYTVHLGSDTL--G 86 II G S P+ V L + C G L+ + WVLTAAHC +N V LG+ ++ Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTTC 144 + Q + K F +P Y T DL L++L +A+++ V + LP + + PGT C Sbjct: 61 EPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDDVKPGTMC 120 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV----YKDLLENSMLCAGIPDSKKNA 200 V+GWG T + ++ L V++ +I + C + ++ +M+CAG +++ Sbjct: 121 QVAGWGRTHNS-ASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 179 Query: 201 CNGDSGGPLVCRGTLQGLVSWG-TFPCGQPNDPGVYTQVC-KFTKWINDTMK 250 CNGDSG PL+C G +G+ S+G CG P PGVY + K WI T+K Sbjct: 180 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIMTIK 231 >2RDL-A nrPDB Length = 226 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 73/231 (31%), Positives = 113/231 (48%), Gaps = 13/231 (5%) Query: 30 IIDGAPCARGSHPWQVAL--LSGNQLH--CGGVLVNERWVLTAAHCKMNEYTVHLGSDT- 84 II G C + P+ L ++ C G L+ +V+TAAHC TV LG+ Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 85 -LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVK--KVRLPSRCEPPG 141 + + Q+++ K F HP Y + +ND+ML+KL +A L+ V + S PPG Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVLNDIMLLKLKEKANLTLGVGTLPISAKSNSIPPG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 C GWG T + L V ++++ PQ C K ++D + LC G P +N Sbjct: 121 RVCRAVGWGRTNVNEPP-SDTLQEVKMRILDPQAC-KHFEDFHQEPQLCVGNPKKIRNVY 178 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GDSGGPL+C G QG+ S+ P V+T++ + WIN ++++ Sbjct: 179 KGDSGGPLLCAGIAQGIASYVLR---NAKPPSVFTRISHYRPWINKILREN 226 >5LHN-A nrPDB Length = 247 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 78/247 (31%), Positives = 121/247 (48%), Gaps = 28/247 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ------LHCGGVLVNERWVLTAAHCK-----MNEYTV 78 I+ G + PW A+ N+ CGG L++ WV +AAHC Y V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 79 HLG--SDTLGDRRAQRIKASKSFRHPGYSTQT--HVNDLMLVKLNSQ----ARLSSMVKK 130 +LG ++ + + + + H Y + + ND+ L+K+ + A+ S ++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLAYHNDIALLKIRTSTGQCAQPSRSIQT 120 Query: 131 VRLPSR--CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLEN 186 + LP R P G+ C ++G+G + D +P +L VKL+S + C + Y + Sbjct: 121 IALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQPHYYGSEINY 180 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFT 242 MLCA P+ K ++C GDSGGPL+C TL G+VSWG C + N PGVYT+V F Sbjct: 181 KMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGR-GCAEKNKPGVYTRVSHFL 239 Query: 243 KWINDTM 249 WI + Sbjct: 240 DWIQSHI 246 >4KKD-A nrPDB Length = 433 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 76/289 (26%), Positives = 114/289 (39%), Gaps = 48/289 (16%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALL-------SGNQLHCGGVL 59 LP + + Q +II G G PWQ ++ ++ G L Sbjct: 134 LPTCLPECGQPSRSLPSLVQ--RIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGAL 191 Query: 60 VNERWVLTAAHCKMN-------------EYTVHLGSDTLGDRR-AQRIKASKSFRHPGYS 105 ++ W+LTAAH + TV+LG + D+ A A++ HP ++ Sbjct: 192 LSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFN 251 Query: 106 TQTHVNDLMLVKLNSQARLSSMVKKVRLP---SRCEPPGTTCTVSGWG----------TT 152 Q + +D+ LV+L L V V LP P V+GWG Sbjct: 252 IQNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEII 311 Query: 153 TSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-----LENSMLCAGIPDSKKNACNGDSGG 207 +S T L V + ++ +C Y+ + +M CAG + K+ C GDSG Sbjct: 312 SSGTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGE 371 Query: 208 PLV------CRGTLQGLVSW-GTFPCGQPNDPGVYTQVCKFTKWINDTM 249 V R +QGLVSW G CG GVYT+V + W+ + M Sbjct: 372 AFVIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >1ZJK-A nrPDB Length = 403 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 80/266 (30%), Positives = 121/266 (45%), Gaps = 32/266 (12%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP+ + L+ T G +I G G PWQV +L G G L+ + WVL Sbjct: 144 LPVCEPVCGLSARTTG-----GQIYGGQKAKPGDFPWQVLILGGT--TAAGALLYDNWVL 196 Query: 67 TAAHC------KMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQT-HVNDLMLVKLN 119 TAAH + + +G+ + + F H GY+ ND+ L+KLN Sbjct: 197 TAAHAVYEQKHDASALDIRMGTLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLN 256 Query: 120 SQARLSSMVKKVRLPSRCEPP----GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQD 175 ++ ++S + + LP + T SGWG T +LM VD+ ++ Q Sbjct: 257 NKVVINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQK 314 Query: 176 CTKVY------KDLLENSMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSWGT 223 CT Y + + +MLCAG+ K++C GDSGG LV R + G+VSWG+ Sbjct: 315 CTAAYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGS 374 Query: 224 FPCGQPNDPGVYTQVCKFTKWINDTM 249 CG+ GVYT+V + WI + + Sbjct: 375 MNCGEAGQYGVYTKVINYIPWIENII 400 >1A5I-A nrPDB Length = 265 Score = 241 bits (615), Expect = 3e-64, Method: Composition-based stats. Identities = 87/249 (34%), Positives = 115/249 (46%), Gaps = 32/249 (12%) Query: 32 DGAPCARGSHPWQVALL------SGNQLHCGGVLVNERWVLTAAHCKMNEY-----TVHL 80 G SHPWQ A+ SG + CGG+L++ WVLTAAHC Y V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 81 GSDTLGDR--RAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQ----ARLSSMVKKVRLP 134 G Q K K H + T+ ND+ L++L S A+ S V+ + LP Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDTYNNDIALLQLKSDSPQCAQESDSVRAICLP 135 Query: 135 SRC--EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLC 190 P T C +SG+G S + L V+L C + + N+MLC Sbjct: 136 EANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFLFNKTVTNNMLC 195 Query: 191 AGIPDSKK------NACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCK 240 AG S + +AC GDSGGPLVC TL G++SWG CG+ + PGVYT+V Sbjct: 196 AGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWGV-GCGEKDVPGVYTKVTN 254 Query: 241 FTKWINDTM 249 + WI D M Sbjct: 255 YLGWIRDNM 263 >1ELV-A nrPDB Length = 333 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 75/278 (26%), Positives = 118/278 (42%), Gaps = 45/278 (16%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP + + + E E+ +II G+ + PWQV + GG L+NE WVL Sbjct: 63 LPKCVPVCGVPREPFEEK---QRIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVL 116 Query: 67 TAAHCK--MNEYTVHLGSDTLGDR---RAQRIKASKSFRHPGYS-------TQTHVNDLM 114 TAAH E T+++GS ++ +++ + F HPG+ ND+ Sbjct: 117 TAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLAVPEGRTNFDNDIA 176 Query: 115 LVKLNSQARLSSMVKKVRLP----SRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKL 170 LV+L ++ V + LP G +SGWG T D L + + Sbjct: 177 LVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR--AVRLKAARLPV 234 Query: 171 ISPQDCTKVYKD---------LLENSMLCAGIPDSKKNACNGDSGGPLVCRG-------T 214 + C +V + + +M+CAG + ++C GDSGG + Sbjct: 235 APLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFY 293 Query: 215 LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GLVSWG CG G+YT+V + WI TM+++ Sbjct: 294 AAGLVSWGPQ-CGT---YGLYTRVKNYVDWIMKTMQEN 327 >1YC0-A nrPDB Length = 283 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 84/245 (34%), Positives = 119/245 (48%), Gaps = 22/245 (8%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLGSD 83 +II G+ GSHPW A+ G+ C G LV+ WV++AAHC + +V LG Sbjct: 35 RIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 93 Query: 84 TLGDRRA--QRIKASKSFRHPGYSTQT-HVNDLMLVKLNSQ----ARLSSMVKKVRLPS- 135 Q K + YS +DL+L++L + A S V+ + LP Sbjct: 94 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 153 Query: 136 -RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAG 192 P G C ++GWG + S L V L++ C+ +VY + +MLCAG Sbjct: 154 GSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAG 213 Query: 193 IPDSKKNACNGDSGGPLVCRG----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 D K +AC GDSGGPL C L G++SWG CG+ + PGVYT+V + WIND Sbjct: 214 YFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVANYVDWINDR 272 Query: 249 MKKHR 253 ++ R Sbjct: 273 IRPPR 277 >1FIW-A nrPDB Length = 290 Score = 240 bits (614), Expect = 3e-64, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 103/249 (41%), Gaps = 30/249 (12%) Query: 30 IIDGAPCARGSHPWQVALL------SGNQLHCGGVLVNERWVLTAAHCKM-----NEYTV 78 II G A G+ PW V+L + CGG L+N +W+LTAAHC ++ + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 79 HLGSDTLG-------DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKV 131 G+ + Q K H YS + ND+ L+K+ + Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSASSEANDIALMKITPPVTCGHFIGPG 120 Query: 132 RLPSRCEPPGT---TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLEN 186 LP P TC V+GWG L V LI C + Y + + Sbjct: 121 CLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCNSTRWYNGRIRS 180 Query: 187 SMLCAGIPDSKKNACNGDSGGPLVCRG------TLQGLVSWGTFPCGQPNDPGVYTQVCK 240 + +CAG P+ K + C GDSGGPL+C+ + G+ SWG C + PGVYT Sbjct: 181 TNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWGV-GCARAKRPGVYTSTWS 239 Query: 241 FTKWINDTM 249 + WI + Sbjct: 240 YLNWIASKI 248 >2V35-A nrPDB Length = 240 Score = 240 bits (613), Expect = 4e-64, Method: Composition-based stats. Identities = 68/242 (28%), Positives = 110/242 (45%), Gaps = 21/242 (8%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ----LHCGGVLVNERWVLTAAHCKMNE--YTVHLGSD 83 ++ G R S P Q++L + CGG L+ + WV+TAAHC E + V +G Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 84 TL--GDRRAQRIKASKSFRHPGYSTQTH--VNDLMLVKLNSQARLSSMVKKVRLPSRC-- 137 L D Q + K HP ++T D+ L++L L+S V+ LP Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTI 120 Query: 138 EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKDLLENSMLCAGIPD 195 + C ++GWG T + L + + C + + ++NSM+CAG D Sbjct: 121 LANNSPCYITGWGLTRTNG-QLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAG-GD 178 Query: 196 SKKNACNGDSGGPLVC----RGTLQGLVSWGTF-PCGQPNDPGVYTQVCKFTKWINDTMK 250 ++ C GDSGGPL C + + G+ S+ + C P V+T+V + WIN+ + Sbjct: 179 GVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIA 238 Query: 251 KH 252 + Sbjct: 239 SN 240 >4IGD-A nrPDB Length = 406 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 79/272 (29%), Positives = 115/272 (42%), Gaps = 36/272 (13%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLS-GNQLHCGGVLVNERWV 65 LP + + L +I +G P +G+ PW L Q CGG L+ W+ Sbjct: 136 LPTCLPVCGLPK---FSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWI 192 Query: 66 LTAAHC------------------KMNEYTVHLGSD--TLGDRRAQRIKASKSFRHPGYS 105 +TAAHC +++ + LG D Q + + HP Y Sbjct: 193 VTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYD 252 Query: 106 TQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMC 165 T ND+ LV+L L++ V + LP + G VSGWG FP LM Sbjct: 253 PNTFENDVALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQ--RFPETLME 310 Query: 166 VDVKLISPQDCTKVY---KDLLENSMLCAGIPDSKKNACNGDSGGPLVC------RGTLQ 216 +++ ++ C K Y K + M+CAG + K+AC GDSGGP+V + L Sbjct: 311 IEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLV 370 Query: 217 GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 G VSWG CG+ + GVY+ + WI Sbjct: 371 GTVSWGDD-CGKKDRYGVYSYIHHNKDWIQRV 401 >4XDE-A nrPDB Length = 257 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 85/241 (35%), Positives = 115/241 (47%), Gaps = 25/241 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN-----EYTVHLG--S 82 ++ G RG+HP+ AL G+ C G L+ WVLTAAHC + + TV LG Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS-FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 83 DTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQAR-----LSSMVKKVRLPSRC 137 Q + H +S ++ +DL L++L A LS V+ V LPS Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVSLPSGA 121 Query: 138 EPP--GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAGI 193 P T C V+GWG + S L V +S + C+ V+ + MLCAG Sbjct: 122 ARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGF 181 Query: 194 PDSKKNACNGDSGGPLVCRG-------TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 + +AC GDSGGPLVC TLQG++SWG+ CG N PGVYT V + WI Sbjct: 182 LEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVYTDVAYYLAWIR 240 Query: 247 D 247 + Sbjct: 241 E 241 >5TO3-B nrPDB Length = 409 Score = 237 bits (605), Expect = 4e-63, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 114/258 (44%), Gaps = 36/258 (13%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVKKVRL 133 V +G T +R ++I K + HP Y+ + D+ L+KL S + V L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 134 PSRC-----EPPGTTCTVSGWGT-----TTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL 183 P R G V+GWG T + PS L V++ ++ C + Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIR 180 Query: 184 LENSMLCAGI---PDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGV 234 + ++M CAG + +AC GDSGGP V R G+VS G C + G Sbjct: 181 ITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA-GCDRDGKYGF 239 Query: 235 YTQVCKFTKWINDTMKKH 252 YT V + KWI + + Sbjct: 240 YTHVFRLKKWIQKVIDQF 257 >4IW4-E nrPDB Length = 279 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 74/266 (27%), Positives = 109/266 (40%), Gaps = 46/266 (17%) Query: 30 IIDGAPCARGSHPWQVALL-------SGNQLHCGGVLVNERWVLTAAHCKMN-------- 74 II G G PWQ ++ ++ G L++ W+LTAAH + Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 75 -----EYTVHLGSDTLGDRR-AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 TV+LG + D+ A A++ HP ++ Q + +D+ LV+L L V Sbjct: 61 PVSKEHVTVYLGLHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIALVQLQEPVPLGPHV 120 Query: 129 KKVRLP---SRCEPPGTTCTVSGWG----------TTTSPDVTFPSDLMCVDVKLISPQD 175 V LP P V+GWG +S T L V + ++ + Sbjct: 121 MPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAE 180 Query: 176 CTKVYKDL-----LENSMLCAGIPDSKKNACNGDSGGPLV------CRGTLQGLVSW-GT 223 C Y+ + +M CAG + K+ C GDSGG V R +QGLVSW G Sbjct: 181 CKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQRWVVQGLVSWGGP 240 Query: 224 FPCGQPNDPGVYTQVCKFTKWINDTM 249 CG GVYT+V + W+ + M Sbjct: 241 EECGSKQVYGVYTKVSNYVDWVWEQM 266 >2R0L-A nrPDB Length = 248 Score = 236 bits (602), Expect = 8e-63, Method: Composition-based stats. Identities = 84/244 (34%), Positives = 118/244 (48%), Gaps = 22/244 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLGSDT 84 II G+ GSHPW A+ G+ C G LV+ WV++AAHC + +V LG Sbjct: 1 IIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 85 LGDRRA--QRIKASKSFRHPGYSTQT-HVNDLMLVKLNSQ----ARLSSMVKKVRLPS-- 135 Q K + YS +DL+L++L + A S V+ + LP Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPG 119 Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCT--KVYKDLLENSMLCAGI 193 P G C ++GWG + S L V L++ C+ +VY + +MLCAG Sbjct: 120 STFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGY 179 Query: 194 PDSKKNACNGDSGGPLVCR----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 D K +AC GDSGGPL C L G++SWG CG+ + PGVYT+V + WIND + Sbjct: 180 FDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVANYVDWINDRI 238 Query: 250 KKHR 253 + R Sbjct: 239 RPPR 242 >4J1Y-A nrPDB Length = 397 Score = 236 bits (602), Expect = 9e-63, Method: Composition-based stats. Identities = 75/278 (26%), Positives = 118/278 (42%), Gaps = 45/278 (16%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP + + + E E+A + I G+ + PWQV + GG L+NE WVL Sbjct: 127 LPKCVPVCGVPREPFEEKA---RAIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVL 180 Query: 67 TAAHCK--MNEYTVHLGSDTLGDR---RAQRIKASKSFRHPGYS-------TQTHVNDLM 114 TAAH E T+++GS ++ +++ + F HPG+ ND+ Sbjct: 181 TAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIA 240 Query: 115 LVKLNSQARLSSMVKKVRLP----SRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKL 170 LV+L ++ V + LP G +SGWG T D L + + Sbjct: 241 LVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR--AVRLKAARLPV 298 Query: 171 ISPQDCTKVYKD---------LLENSMLCAGIPDSKKNACNGDSGGPLVCRG-------T 214 + C +V + + +M+CAG + ++C GDSGG + Sbjct: 299 APLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFY 357 Query: 215 LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 GLVSWG CG G+YT+V + WI TM+++ Sbjct: 358 AAGLVSWGPQ-CGT---YGLYTRVKNYVDWIMKTMQEN 391 >4FXG-H nrPDB Length = 242 Score = 234 bits (598), Expect = 2e-62, Method: Composition-based stats. Identities = 74/243 (30%), Positives = 112/243 (46%), Gaps = 27/243 (11%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC------KMNEYTVHLGSD 83 I G G PWQV +L G G L+ + WVLTAAH + + +G+ Sbjct: 1 IYGGQKAKPGDFPWQVLILGGT--TAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 84 TLGDRRAQRIKASKSFRHPGYSTQT-HVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP-- 140 + + F H GY+ ND+ L+KLN++ ++S + + LP + Sbjct: 59 KRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFM 118 Query: 141 --GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY------KDLLENSMLCAG 192 T SGWG T +LM VD+ ++ Q CT Y + + +MLCAG Sbjct: 119 RTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTAAYEKPPYPRGSVTANMLCAG 176 Query: 193 IPDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 + K++C GD+GG LV R + G+VSWG+ CG+ GVYT+V + WI Sbjct: 177 LESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIE 236 Query: 247 DTM 249 + + Sbjct: 237 NII 239 >1ELT-A nrPDB Length = 236 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 68/239 (28%), Positives = 113/239 (47%), Gaps = 22/239 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQ----LHCGGVLVNERWVLTAAHCKM--NEYTVHLGSD 83 ++ G S PWQ++L + CGG L+ + WV+TAAHC + V LG Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 84 TL--GDRRAQRIKASKSFRHPGYSTQTH--VNDLMLVKLNSQARLSSMVKKVRLPSRCE- 138 L + + Q + + F H G+++ D+ L++LN+QA L+S V+ LP + Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQI 120 Query: 139 -PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTK--VYKDLLENSMLCAGIPD 195 P C ++GWG T++ L + + C+ + ++ +M+CAG Sbjct: 121 LPNNNPCYITGWGKTSTGGP-LSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAG--G 177 Query: 196 SKKNACNGDSGGPLVCR----GTLQGLVSW-GTFPCGQPNDPGVYTQVCKFTKWINDTM 249 + CNGDSGGPL C+ + G+ S+ + C P V+T+V + W+N M Sbjct: 178 GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM 236 >2ZKS-A nrPDB Length = 240 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 71/229 (31%), Positives = 107/229 (46%), Gaps = 12/229 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE---YTVHLGSDTLG 86 II G S P+ +L CGGVLV+ +WVLTAAHC + LG TL Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTL- 59 Query: 87 DRRAQRIKASKSFRHPGYSTQ-THVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 D + +HP Y NDL L++L+ + + S ++ + LPS+ + GT Sbjct: 60 DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGTR 119 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC--TKVYKDLLENSMLCAGIPDSKKNAC 201 C+++GWG T L +D++++ + C ++ + L SM+C + C Sbjct: 120 CSMAGWGLTHQGG-RLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCLAADSKDQAPC 178 Query: 202 NGDSGGPLVC--RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 GDSGGPLVC L G++S+ + C P V T V + WI Sbjct: 179 KGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRKV 227 >2XXL-A nrPDB Length = 408 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 73/263 (27%), Positives = 114/263 (43%), Gaps = 40/263 (15%) Query: 27 GDKIIDGAPCARGSHPWQVALLS----GNQLHCGGVLVNERWVLTAAHCK----MNEYTV 78 ++ +G S PW L ++ CGG +++ER++LTAAHC + Y + Sbjct: 116 SQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGLQNDLYEI 175 Query: 79 HLGSDTLGDRRA--------------QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARL 124 LG + + K H Y + ++D+ L+KLN Sbjct: 176 RLGEHRISTEEDCRQQGRKKKCAPPVVNVGIEKHLIHEKYDARHIMHDIALLKLNRSVPF 235 Query: 125 SSMVKKVRLPSRCE-----PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV 179 +K + LP E +T V+GWGTT + L+ +V L C++ Sbjct: 236 QKHIKPICLPITDELKEKAEQISTYFVTGWGTTENGSS--SDVLLQANVPLQPRSACSQA 293 Query: 180 YKDLLENSMLCAGIPDSKKNACNGDSGGPLVC----------RGTLQGLVSWGTFPCGQP 229 Y+ + S LC G D +++C GDSGGPL + G+VS G CGQ Sbjct: 294 YRRAVPLSQLCVGGGDL-QDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQGVVTCGQI 352 Query: 230 NDPGVYTQVCKFTKWINDTMKKH 252 + PG+YT V ++ +WI DTM + Sbjct: 353 SLPGLYTNVGEYVQWITDTMASN 375 >4DJZ-B nrPDB Length = 251 Score = 227 bits (580), Expect = 3e-60, Method: Composition-based stats. Identities = 76/249 (30%), Positives = 109/249 (43%), Gaps = 33/249 (13%) Query: 30 IIDGAPCARGSHPWQVALLS-GNQLHCGGVLVNERWVLTAAHC----------------- 71 I +G P +G+ PW L Q CGG L+ W++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 72 -KMNEYTVHLGSD--TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128 +++ + LG D Q + + HP Y T ND+ LV+L L++ V Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFV 120 Query: 129 KKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY---KDLLE 185 + LP + G VSGWG FP LM +++ ++ C K Y K + Sbjct: 121 MPICLPEGPQQEGAMVIVSGWGKQFLQ--RFPETLMEIEIPIVDHSTCQKAYAPLKKKVT 178 Query: 186 NSMLCAGIPDSKKNACNGDSGGPLVC------RGTLQGLVSWGTFPCGQPNDPGVYTQVC 239 M+CAG + K+AC GDSGGP+V + L G VSWG CG+ + GVY+ + Sbjct: 179 RDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGDD-CGKKDRYGVYSYIH 237 Query: 240 KFTKWINDT 248 WI Sbjct: 238 HNKDWIQRV 246 >1FON-A nrPDB Length = 240 Score = 227 bits (579), Expect = 4e-60, Method: Composition-based stats. Identities = 71/243 (29%), Positives = 109/243 (44%), Gaps = 25/243 (10%) Query: 32 DGAPCARGSHPWQVALLSGN----QLHCGGVLVNERWVLTAAHCKMNE--YTVHLGSDT- 84 +G S WQV+L CGG L+ WV+TA HC Y V LG Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 85 -LGDRRAQRIKA--SKSFRHPGYSTQTH--VNDLMLVKLNSQARLSSMVKKVRLPSRCE- 138 + + Q I F HP +++ ND+ LVKL+ A+L V+ LP + Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVACGNDIALVKLSRSAQLGDKVQLANLPPAGDI 120 Query: 139 -PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV--YKDLLENSMLCAGIPD 195 P C +SGWG + P L + + + C++ + ++ +M+CAG Sbjct: 121 LPNEAPCYISGWGRLYTGGP-LPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAGGDT 179 Query: 196 SKKNACNGDSGGPLVC-----RGTLQGLVSWGT-FPCGQPNDPGVYTQVCKFTKWINDTM 249 ++ CNGDSGGPL C + G+ S+ + F C P V+T+V F WI++T+ Sbjct: 180 --RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDETI 237 Query: 250 KKH 252 + Sbjct: 238 ASN 240 >2XRC-A nrPDB Length = 565 Score = 223 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 79/236 (33%), Positives = 108/236 (45%), Gaps = 24/236 (10%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDT 84 +I+ G G PWQVA+ + + CGG+ + W+LTAAHC K + Y + Sbjct: 321 RIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVD 380 Query: 85 LGDRRAQRI---KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP------S 135 +RI + H Y+ T+ ND+ L+++ +P Sbjct: 381 WIHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSP 440 Query: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIP 194 P TC VSGWG + F L +VKLIS C+K Y + M CAG Sbjct: 441 YLFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTY 496 Query: 195 DSKKNACNGDSGGPLVCRG-----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 D +AC GDSGGPLVC + G+VSWG CG+P PGVYT+V + WI Sbjct: 497 DGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 551 >5KWM-A nrPDB Length = 230 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 63/219 (28%), Positives = 99/219 (45%), Gaps = 8/219 (3%) Query: 30 IIDGAPCARGSHPWQVALLSGN-QLHCGGVLVNERWVLTAAHCKMN----EYTVHLGSDT 84 I+ G HP+ VAL++ + Q CGG L V+TAAHC + + V G Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 + K + + HP Y D+ ++ L + + + ++ + P T Sbjct: 61 MSSNEGTVSKVTNVWVHPEYQDAAKGFDVSVLTLEAPVK-EAPIELAKADDAGYAPDTAA 119 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGD 204 T+ GWG T+ L V + S C + Y + ++M+CAG+P+ + C GD Sbjct: 120 TILGWGNTSEGG-QQADHLQKATVPVNSDDTCKQAYGEYTPDAMVCAGVPEGGVDTCQGD 178 Query: 205 SGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTK 243 SGGP+V L G+ SWG C +P PGVY +V + Sbjct: 179 SGGPMVVNNKLIGVTSWGE-GCARPGKPGVYARVGAYYD 216 >1GPZ-A nrPDB Length = 399 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 72/271 (26%), Positives = 107/271 (39%), Gaps = 37/271 (13%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 +P + + + + Q II G G+ PWQV + GG L+ +RW+L Sbjct: 138 IPRCLPVCGKPVNPVEQRQQ---IIGGQKAKMGNFPWQV--FTNIHGRGGGALLGDRWIL 192 Query: 67 TAAHC---------KMNEYTVHLGSDTLGD-RRAQRIKASKSFRHPGYSTQTHVN---DL 113 TAAH V LG + + + + HP Y N D+ Sbjct: 193 TAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDI 252 Query: 114 MLVKLNSQARLSSMVKKVRLPSRC--EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLI 171 L++L + L + + LP G VSG+G DL V + + Sbjct: 253 ALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVA 309 Query: 172 SPQDCTKVYKD-----LLENSMLCAGIPDSKKNACNGDSGG------PLVCRGTLQGLVS 220 +PQ C + + +M CAG P K++AC GDSGG P R G+VS Sbjct: 310 NPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVS 369 Query: 221 WGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 WG C + G YT+V + WI M++ Sbjct: 370 WG-IGCSRG--YGFYTKVLNYVDWIKKEMEE 397 >5UBM-A nrPDB Length = 252 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 71/256 (27%), Positives = 110/256 (42%), Gaps = 42/256 (16%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK--MNEYTVHLGSDTLG 86 +II G+ + PWQV + GG L+NE WVLTAAH E T+++GS ++ Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 87 DR---RAQRIKASKSFRHPGYS-------TQTHVNDLMLVKLNSQARLSSMVKKVRLP-- 134 +++ + F HPG+ ND+ LV+L ++ V + LP Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGT 117 Query: 135 --SRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD---------L 183 G +SGWG T D L + + + C +V + + Sbjct: 118 SSDYNLMDGDLGLISGWGRTEKRDR--AVRLKAARLPVAPLRKCKEVKVEKPTADAEAYV 175 Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLVCRG-------TLQGLVSWGTFPCGQPNDPGVYT 236 +M+CAG + ++C GDSGG + GLVSWG CG G+YT Sbjct: 176 FTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---YGLYT 230 Query: 237 QVCKFTKWINDTMKKH 252 +V + WI TM+++ Sbjct: 231 RVKNYVDWIMKTMQEN 246 >1EQ9-A nrPDB Length = 222 Score = 221 bits (564), Expect = 2e-58, Method: Composition-based stats. Identities = 70/228 (30%), Positives = 116/228 (50%), Gaps = 12/228 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLGSDT 84 I+ G G +P+QV+L CG +++ VLTAAHC +N VH+G++ Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP-PGTT 143 L + + + Y ND+ LV L + + + +V+ ++L + E Sbjct: 61 LSESGD-VYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLESNP 119 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG 203 CT++GWG+T T P+ L +++ + + C + + + +S +C + + AC+G Sbjct: 120 CTLTGWGSTRLGGNT-PNALQEIELIVHPQKQCERD-QWRVIDSHICT-LTKRGEGACHG 176 Query: 204 DSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 DSGGPLV G G+VS+G+ PC +P VYT+V F WIN +KK Sbjct: 177 DSGGPLVANGAQIGIVSFGS-PCAL-GEPDVYTRVSSFVSWINANLKK 222 >1MD7-A nrPDB Length = 328 Score = 221 bits (563), Expect = 2e-58, Method: Composition-based stats. Identities = 71/270 (26%), Positives = 106/270 (39%), Gaps = 37/270 (13%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 +P + + + Q +II G G+ PWQV + GG L+ +RW+L Sbjct: 70 IPRCLPVCGKPVNPVE---QRQRIIGGQKAKMGNFPWQV--FTNIHGRGGGALLGDRWIL 124 Query: 67 TAAHC---------KMNEYTVHLGSDTLGD-RRAQRIKASKSFRHPGYSTQTHVN---DL 113 TAAH V LG + + + + HP Y N D+ Sbjct: 125 TAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDI 184 Query: 114 MLVKLNSQARLSSMVKKVRLPSRC--EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLI 171 L++L + L + + LP G VSG+G DL V + + Sbjct: 185 ALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVA 241 Query: 172 SPQDCTKVYKD-----LLENSMLCAGIPDSKKNACNGDSGG------PLVCRGTLQGLVS 220 +PQ C + + +M CAG P K++AC GD+GG P R G+VS Sbjct: 242 NPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVS 301 Query: 221 WGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 WG C + G YT+V + WI M+ Sbjct: 302 WG-IGCSRG--YGFYTKVLNYVDWIKKEME 328 >4BXW-A nrPDB Length = 423 Score = 221 bits (563), Expect = 3e-58, Method: Composition-based stats. Identities = 64/245 (26%), Positives = 102/245 (41%), Gaps = 24/245 (9%) Query: 29 KIIDGAPCARGSHPWQVALLSGNQL-HCGGVLVNERWVLTAAHCKMNE--YTVHLGS-DT 84 +I++G C G PWQ AL+ + CGG +++ +VLTAAHC +V +G D Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 85 LGDRRAQRIKASKSFRHPGYST---------QTHVNDLMLVKLNSQARLSSMVKKVRLPS 135 + K + H + + D+ ++++ + + S V LP+ Sbjct: 229 SRIETGPLLSVDKIYVHKKFVPPQKAYKFDLAAYDYDIAIIQMKTPIQFSENVVPACLPT 288 Query: 136 RCEPPG-----TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLC 190 VSG+G L + V + C + + +M C Sbjct: 289 ADFANQVLMKQDFGIVSGFGRIVEKGPK-SKTLKVLKVPYVDRHTCMVSSETPITPNMFC 347 Query: 191 AGIPDSKKNACNGDSGGPL--VCRGT--LQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 AG ++AC GDSGGP V R T + G+VS G C + G YT++ KF WI Sbjct: 348 AGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGE-GCARNGKYGNYTKLSKFIPWIK 406 Query: 247 DTMKK 251 M++ Sbjct: 407 RIMRQ 411 >5O32-I nrPDB Length = 244 Score = 220 bits (560), Expect = 6e-58, Method: Composition-based stats. Identities = 79/235 (33%), Positives = 107/235 (45%), Gaps = 24/235 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 I+ G G PWQVA+ + + CGG+ + W+LTAAHC K + Y + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 86 GDRRAQRI---KASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP------SR 136 +RI + H Y+ T+ ND+ L+++ +P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYNAGTYQNDIALIEMKKDGNKKDCELPRSIPACVPWSPY 120 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENS-MLCAGIPD 195 P TC VSGWG + F L +VKLIS C+K Y + M CAG D Sbjct: 121 LFQPNDTCIVSGWGREKDNERVFS--LQWGEVKLISN--CSKFYGNRFYEKEMECAGTYD 176 Query: 196 SKKNACNGDSGGPLVCRG-----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245 +AC GDSGGPLVC + G+VSWG CG+P PGVYT+V + WI Sbjct: 177 GSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVANYFDWI 230 >4WJG-C nrPDB Length = 315 Score = 219 bits (558), Expect = 1e-57, Method: Composition-based stats. Identities = 67/276 (24%), Positives = 110/276 (39%), Gaps = 41/276 (14%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP + A +I+ G A+GS PWQ ++S + L G L+NE+W+L Sbjct: 51 LPECEAVCGKPKNPANP---VQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLL 107 Query: 67 TAA-HCKMNEYTVHLGSD-----TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS 120 T A + +N D TL + Q ++ K HP YS D+ L+KL Sbjct: 108 TTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQ 163 Query: 121 QARLSSMVKKVRLPSRCEPP-GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKV 179 + ++ V + LPS+ G VSGWG + + F L V + + C + Sbjct: 164 KVSVNERVMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRH 221 Query: 180 YKD-----------------LLENSMLCAGIPDSKKNACNGDSGGPLVCR------GTLQ 216 Y+ +L CAG+ +++ C GD+G Sbjct: 222 YEGSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYAT 281 Query: 217 GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 G++S+ C + GVY +V W+ T+ ++ Sbjct: 282 GILSF-DKSCAVA-EYGVYVKVTSIQDWVQKTIAEN 315 >3I77-A nrPDB Length = 230 Score = 215 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 69/235 (29%), Positives = 108/235 (45%), Gaps = 19/235 (8%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLGSD 83 ++ G A+G P+ V L++ N+ CGG L + VLTAAHC T G Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 84 TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTT 143 L A +++++K + PG++ +T+ D L+KL +++ + T Sbjct: 61 DLQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQP----TLKIATTTAYNQGT 116 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPD-SKKNAC 201 TV+GWG + L+ +V +S C + + N M+CAG PD + C Sbjct: 117 FTVAGWGANREGG-SQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYPDTGGVDTC 175 Query: 202 NGDSGGPLVCR-----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 GDSGGP+ + G+VSWG + C +P PGVYT+V F I + Sbjct: 176 QGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFASAIASAART 229 >1AE5-A nrPDB Length = 225 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 69/230 (30%), Positives = 112/230 (48%), Gaps = 19/230 (8%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNE----YTVHLGSDTL 85 I+ G P+ ++ + + CGG L++ R+V+TAA C ++ TV LG+ L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 86 --GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEPPG 141 +R++++ + S GY Q ++NDLML++L+ +A L+S V + LP + G Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAG 120 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNAC 201 T C V+GWG+ S V+V + C + +C G+ + C Sbjct: 121 TRCQVAGWGSQRSGG-RLSRFPRFVNVTVTPEDQC--------RPNNVCTGVLTRRGGIC 171 Query: 202 NGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 NGD G PLVC G G+ S+ PCG+ P +T+V F WI+ + Sbjct: 172 NGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLNN 219 >2OLG-A nrPDB Length = 278 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 74/267 (27%), Positives = 121/267 (45%), Gaps = 42/267 (15%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALLSGN-----QLHCGGVLVNERWVLTAAHCKMNEY 76 G + + DKI++G PW + N Q CGG L+N R+++TAAHC Sbjct: 15 GYQVEADKILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRV 74 Query: 77 TVHLGSDT---LGD------------------RRAQRIKASKSFRHPGYSTQTHV--NDL 113 +G+ LG+ + + ++ +HP Y + +D+ Sbjct: 75 LRVVGALNKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDI 134 Query: 114 MLVKLNSQARLSSMVKKVRLPS--RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLI 171 L++LN Q ++ ++ V LP G TV GWG T + + + + V ++ Sbjct: 135 ALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTETG--QYSTIKQKLAVPVV 192 Query: 172 SPQDCTKVYK---DLLENSMLCAGIPDSKKNACNGDSGGPL-----VCRGTLQGLVSWGT 223 + C K + + +S LCAG + K++C GDSGGPL + L+GLVS+G Sbjct: 193 HAEQCAKTFGAAGVRVRSSQLCAG-GEKAKDSCGGDSGGPLLAERANQQFFLEGLVSFGA 251 Query: 224 FPCGQPNDPGVYTQVCKFTKWINDTMK 250 CG PG+YT+V K+ WI ++ Sbjct: 252 T-CGTEGWPGIYTKVGKYRDWIEGNIR 277 >4X0L-C nrPDB Length = 259 Score = 214 bits (546), Expect = 2e-56, Method: Composition-based stats. Identities = 65/270 (24%), Positives = 108/270 (40%), Gaps = 41/270 (15%) Query: 13 LLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAA-HC 71 + A +I+ G A+GS PWQ ++S + L G L+NE+W+LT A + Sbjct: 1 VCGKPKNPANP---VQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNL 57 Query: 72 KMNEYTVHLGSD-----TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS 126 +N D TL + Q ++ K HP YS D+ L+KL + ++ Sbjct: 58 FLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV----DIGLIKLKQKVSVNE 113 Query: 127 MVKKVRLPSRCEPP-GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD--- 182 V + LPS+ G VSGWG + + F L V + + C + Y+ Sbjct: 114 RVMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYEGSTV 171 Query: 183 --------------LLENSMLCAGIPDSKKNACNGDSGGPLVCR------GTLQGLVSWG 222 +L CAG+ +++ C GD+G G++S+ Sbjct: 172 PEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSF- 230 Query: 223 TFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 C + GVY +V W+ T+ ++ Sbjct: 231 DKSCAVA-EYGVYVKVTSIQDWVQKTIAEN 259 >4LK4-A nrPDB Length = 357 Score = 213 bits (542), Expect = 7e-56, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 110/241 (45%), Gaps = 19/241 (7%) Query: 24 EAQGDKIIDGAPCARGSHPWQVALLSGN-----QLHCGGVLVNERWVLTAAHCKMN---- 74 +II+G+ P VAL+ CGG + R+VLTAAHC + Sbjct: 5 ADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDSRSAA 64 Query: 75 EYTVHLGSDTLGDRRA-QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRL 133 V +G+ L + +RI A K +RH YS +ND+ +V+L + L ++ Sbjct: 65 SVDVIIGAYDLNNSSQGERIAAQKIYRHLSYSPSNLLNDIAIVELAQTSSLPAITLAGPA 124 Query: 134 PSRCEPPGTTCTVSGWGTT-TSPDVTFPSDLMCVDVKLISPQDCTKVYKDLL----ENSM 188 P T TV+GWG T S F L VDV L+S C V + + ++ Sbjct: 125 TRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLCQIVMQHGISSDPNSTN 184 Query: 189 LCAGIPDSKKNACNGDSGGPLVCR-GTLQ-GLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 CA K++C GD+GGP+V + G Q G+VSWG C + GVYT V F WI Sbjct: 185 FCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTGTYGVYTNVSYFRDWIT 242 Query: 247 D 247 Sbjct: 243 K 243 >2QY0-B nrPDB Length = 242 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 70/248 (28%), Positives = 100/248 (40%), Gaps = 34/248 (13%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC---------KMNEYTVHL 80 II G G+ PWQV + GG L+ +RW+LTAAH V L Sbjct: 1 IIGGQKAKMGNFPWQV--FTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 81 GSDTLGD-RRAQRIKASKSFRHPGYSTQTHVN---DLMLVKLNSQARLSSMVKKVRLPSR 136 G + + + + HP Y N D+ L++L + L + + LP Sbjct: 59 GHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDN 118 Query: 137 C--EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-----LLENSML 189 G VSG+G DL V + + +PQ C + + +M Sbjct: 119 DTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMF 175 Query: 190 CAGIPDSKKNACNGDSGG------PLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTK 243 CAG P K++AC GDSGG P R G+VSWG C + G YT+V + Sbjct: 176 CAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG-IGCSRG--YGFYTKVLNYVD 232 Query: 244 WINDTMKK 251 WI M++ Sbjct: 233 WIKKEMEE 240 >1YM0-A nrPDB Length = 238 Score = 212 bits (540), Expect = 1e-55, Method: Composition-based stats. Identities = 70/240 (29%), Positives = 104/240 (43%), Gaps = 19/240 (7%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKMNE----YTVHLGSD 83 I+ G PWQV++ S + CGG ++N+RWV+ AAHC E ++ +G Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 84 TLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS-RCEPP 140 Q F + Y T ND+ ++K V + P + Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDPATLENDVSVIKTAVAITFDINVGPICAPDPANDYV 120 Query: 141 GTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDS--K 197 SGWGT S V P+ L V + + + C VY D + + M+CA Sbjct: 121 YRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICATDNTGMTD 180 Query: 198 KNACNGDSGGPLVCRG-----TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 +++C GDSGGPL + +L G+VSWG C PGVY++V WI DT+ + Sbjct: 181 RDSCQGDSGGPLSVKDGSGIFSLVGIVSWG-IGCAS-GYPGVYSRVGFHAGWITDTITNN 238 >3BEU-A nrPDB Length = 224 Score = 211 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 64/233 (27%), Positives = 102/233 (43%), Gaps = 21/233 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLGSDT 84 ++ G A+G P+ V L + CGG L + VLTAAHC T G Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 L A +++++K + PG++ +T+ D L+KL +++ + T Sbjct: 57 LQSSSAVKVRSTKVLQAPGFTKETYGKDWALIKLAQPINQP----TLKIATTTAYNQGTF 112 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL-LENSMLCAGIPDSKKNACNG 203 TV+GWG + L+ +V +S C + + N M+CAG +++ C G Sbjct: 113 TVAGWGANREGG-SQQRYLLKANVPFVSDAACRSSSSFILVANEMICAGYDTKQEDTCQG 171 Query: 204 DSGGPLVCR-----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 DSGGP+ + G+VSWG C + GVYT+V F I + Sbjct: 172 DSGGPMFRKDNADEWVQVGIVSWGE-GCARKGKYGVYTEVSTFASAIASAART 223 >4F4O-C nrPDB Length = 347 Score = 211 bits (538), Expect = 2e-55, Method: Composition-based stats. Identities = 67/282 (23%), Positives = 111/282 (39%), Gaps = 53/282 (18%) Query: 7 LPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVL 66 LP + Q +I+ G+ A+GS PWQ ++S + L G L+NE+W+L Sbjct: 83 LPECEAVCGKPKNP---VDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLL 139 Query: 67 TAAHCKMNEYTVHLGSDT------------LGDRRAQRIKASKSFRHPGYSTQTHVNDLM 114 T A + LG L + Q ++ K HP ST D+ Sbjct: 140 TTA------KNLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPDNSTV----DIG 189 Query: 115 LVKLNSQARLSSMVKKVRLPSRCE-PPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISP 173 L+KL + ++ V + LPS+ G VSGWG + ++ F L V + + Sbjct: 190 LIKLKQKVPVNERVMPICLPSKDYVNVGLVGYVSGWGR--NANLNFTEHLKYVMLPVADQ 247 Query: 174 QDCTKVYKD-----------------LLENSMLCAGIPDSKKNACNGDSGGPLVCR---- 212 + C + Y+ +L CAG+ +++ C GD+G Sbjct: 248 EKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDD 307 Query: 213 --GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 G++S+ C + + GVY +V WI T+ + Sbjct: 308 DTWYAAGILSF-DKSC-RTAEYGVYVRVTSILDWIQTTIADN 347 >1PPF-E nrPDB Length = 218 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 59/228 (25%), Positives = 100/228 (43%), Gaps = 17/228 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVH----LGSDTL 85 I+ G + P+ V+L CG L+ +V++AAHC N LG+ L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 86 GDRRAQR-IKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC--EPPGT 142 R R + A + GY +ND+++++LN A +++ V+ +LP++ G Sbjct: 61 SRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGV 120 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACN 202 C GWG + S L ++V +++ L S +C + + C Sbjct: 121 QCLAMGWGLLG-RNRGIASVLQELNVTVVT---------SLCRRSNVCTLVRGRQAGVCF 170 Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 GDSG PLVC G + G+ S+ C P + V +F WI+ ++ Sbjct: 171 GDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >2B9L-A nrPDB Length = 394 Score = 206 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 74/264 (28%), Positives = 108/264 (40%), Gaps = 37/264 (14%) Query: 23 EEAQGDKIIDGA-PCARGSHPWQVALLSGN--------QLHCGGVLVNERWVLTAAHCKM 73 E KI G PW VA+L N QL CGG L+ VLT AHC Sbjct: 123 ERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGAHCVN 182 Query: 74 ------NEYTVHLGS-DTLGDRR---AQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQAR 123 + + G DTL ++ Q K + H ++ +T VND+ L+ L+ Sbjct: 183 SYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVVNDVALLLLDRPLV 242 Query: 124 LSSMVKKVRLPSRCEP-PGTTCTVSGWGTTT-SPDVTFPSDLMCVDVKLISPQDCTKVYK 181 + + + LP + + T C SGWG + + L + + + C + Sbjct: 243 QADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKIQLPTVDRDKCQADLR 302 Query: 182 DL-------LENSMLCAGIPDSKKNACNGDSGGPLVC-------RGTLQGLVSWGTFPCG 227 + L+ + +CAG + K+ C GD G PL C R G+V+WG CG Sbjct: 303 NTRLGLKFVLDQTFVCAG-GEQGKDTCTGDGGSPLFCPDPRNPSRYMQMGIVAWG-IGCG 360 Query: 228 QPNDPGVYTQVCKFTKWINDTMKK 251 N PGVY V F WI+ M+ Sbjct: 361 DENVPGVYANVAHFRNWIDQEMQA 384 >6BQM-A nrPDB Length = 506 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 76/248 (30%), Positives = 108/248 (43%), Gaps = 26/248 (10%) Query: 23 EEAQGDKIIDGAPCARGSHPWQVAL--LSGNQLHCGGVLVNERWVLTAAHCKMNEY---- 76 E +II G G P+ VAL + + + CGG + R+VLTAAHC E Sbjct: 4 ESGVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKG 63 Query: 77 TVHLGSDTLGD-RRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPS 135 V LG+ + D A+RI + + H Y T + ND+ +++L V+ Sbjct: 64 DVLLGAFDMNDVNTAERIHVRQIYVHNSYITASMGNDIAVLELERDPLPRRSVQISDSSD 123 Query: 136 -RCEPPGTTCTVSGWGTTTSPDVTFPS---DLMCVDVKLISPQDCTKVYKD--------L 183 + TV G+G D L V V + +C D Sbjct: 124 FNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGSDQDAKNNYSQ 183 Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLVC---RGTLQ-GLVSWGTFPCGQPNDPGVYTQVC 239 L N+ CAG K+AC+GD+GGP+ G Q G+VSWG CG+ N PGVYT + Sbjct: 184 LTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWGD-GCGRANSPGVYTNLS 240 Query: 240 KFTKWIND 247 F W++D Sbjct: 241 VFNDWLDD 248 >2PKA-B nrPDB Length = 152 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 59/150 (39%), Positives = 89/150 (59%), Gaps = 2/150 (1%) Query: 105 STQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSP--DVTFPSD 162 + + +DLML++L S A+++ VK + LP++ G+TC SGWG+ D FP + Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDE 61 Query: 163 LMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWG 222 + CV + L+ C + D + SMLCAG K+ C GDSGGPL+C G QG+ SWG Sbjct: 62 IQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWG 121 Query: 223 TFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 PCG N P +YT++ + WI+DT+ ++ Sbjct: 122 HTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >1SI5-H nrPDB Length = 240 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 67/236 (28%), Positives = 109/236 (46%), Gaps = 18/236 (7%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMN----EYTVHLGSDTL 85 +++G P W V+L N+ CGG L+ E WVLTA C + +Y LG + Sbjct: 1 VVNGIPTRTN-IGWMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDV 59 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 R ++ K + Y + +DL+L+KL A L V + LP+ P T+ Sbjct: 60 HGRGDEKCKQVLNVSQLVYGPE--GSDLVLMKLARPAVLDDFVSTIDLPNYGSTIPEKTS 117 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLE--NSMLCAGIPDSKKNAC 201 C+V GWG T + + L + ++ + C++ ++ + S +CAG C Sbjct: 118 CSVYGWGYTGL--INYDGLLRVAHLYIMGNEKCSQHHRGKVTLNESEICAGAEKIGSGPC 175 Query: 202 NGDSGGPLVCRGTLQ----GLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR 253 GD GGPLVC G++ G C PN PG++ +V + KWI+ + ++ Sbjct: 176 EGDYGGPLVCEQHKMRMVLGVIVPGR-GCAIPNRPGIFVRVAYYAKWIHKIILTYK 230 >2FMJ-A nrPDB Length = 222 Score = 204 bits (520), Expect = 2e-53, Method: Composition-based stats. Identities = 65/233 (27%), Positives = 98/233 (42%), Gaps = 23/233 (9%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK-----MNEYTVHLGSDT 84 ++ G A+G P+ V L + CGG L + VLTAAHC T G Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTC 144 L A +++++K + PGY+ D L+KL +++ + T Sbjct: 57 LQSSSAVKVRSTKVLQAPGYNGT--GKDWALIKLAQPINQP----TLKIATTTAYNQGTF 110 Query: 145 TVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDSKKNACNG 203 TV+GWG + L+ +V +S C Y +L+ N +CAG + C G Sbjct: 111 TVAGWGANREGG-SQQRYLLKANVPFVSDAACRSAYGNELVANEEICAGYDTGGVDTCQG 169 Query: 204 DSGGPLVCR-----GTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 DSGGP+ + G+VSWG C + GVYT+V F I + Sbjct: 170 DSGGPMFRKDNADEWIQVGIVSWGE-GCARKGKYGVYTEVSTFASAIASAART 221 >2HLC-A nrPDB Length = 230 Score = 204 bits (519), Expect = 3e-53, Method: Composition-based stats. Identities = 65/232 (28%), Positives = 107/232 (46%), Gaps = 20/232 (8%) Query: 30 IIDGAPCARGSHPWQV----ALLSGNQLHCGGVLVNERWVLTAAHCKMN--EYTVHLGSD 83 II+G G P+Q L ++ CGG L++ +W+LTAAHC + V+LGS Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 84 TLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGT- 142 + A + + + H ++ T++ND+ L+K+ + ++ +RLPS E Sbjct: 61 VQYEGEA-VVNSERIISHSMFNPDTYLNDVALIKI-PHVEYTDNIQPIRLPSGEELNNKF 118 Query: 143 ---TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDSKK 198 TVSGWG + + V L +I C + Y ++ S +C G K Sbjct: 119 ENIWATVSGWGQSNTDTV----ILQYTYNLVIDNDRCAQEYPPGIIVESTIC-GDTSDGK 173 Query: 199 NACNGDSGGPLVC--RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDT 248 + C GDSGGP V + L G+VS+ + + P +++V + WI Sbjct: 174 SPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWIQQN 225 >1PQ7-A nrPDB Length = 224 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 75/225 (33%), Positives = 108/225 (48%), Gaps = 12/225 (5%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCK----MNEYTVHLGSDTL 85 I+ G + G P+ V++ CGG L+N VLTAAHC + + + GS + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQSGFQIRAGSLSR 60 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPP--GTT 143 S HP YS NDL ++KL++ + RL + P G++ Sbjct: 61 TSGGITS-SLSSVRVHPSYSGNN--NDLAILKLSTSIPSGGNIGYARLAASGSDPVAGSS 117 Query: 144 CTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYK-DLLENSMLCAGIPDSKKNACN 202 TV+GWG T+ + P +L+ V V ++S C Y + N M CAG+ K++C Sbjct: 118 ATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGVSSGGKDSCQ 177 Query: 203 GDSGGPLV-CRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIN 246 GDSGGP+V TL G VSWG C +PN GVY V +I+ Sbjct: 178 GDSGGPIVDSSNTLIGAVSWG-NGCARPNYSGVYASVGALRSFID 221 >2ASU-B nrPDB Length = 234 Score = 201 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 72/238 (30%), Positives = 107/238 (44%), Gaps = 29/238 (12%) Query: 30 IIDGAPCARGSHPWQVALLSG-NQLHCGGVLVNERWVLTAAHCKMN------EYTVHLGS 82 ++ G G+ PW V+L + Q CGG LV E+W+LTA C + Y V LG+ Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 83 ----DTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSR-- 136 G+ QR+ +K P S L+L+KL L+ V + LP Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGSQ------LVLLKLERSVTLNQRVALICLPPEWY 111 Query: 137 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 196 PPGT C ++GWG T + L + +IS Q+C ++ + S +C + Sbjct: 112 VVPPGTKCEIAGWGETKGTGND--TVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLA 169 Query: 197 KKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250 AC GD GGPL C L+G++ C + P V+T+V F WI+ M+ Sbjct: 170 PVGACEGDYGGPLACFTHNSWVLEGIIIPNRV-CARSRWPAVFTRVSVFVDWIHKVMR 226 >5XW8-A nrPDB Length = 133 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 57/134 (42%), Positives = 75/134 (55%), Gaps = 3/134 (2%) Query: 22 GEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLG 81 DKI+ G CA S P+QV+L SG CGG L+N +WV++AAHC + V LG Sbjct: 1 FPTDDDDKIVGGYTCAANSIPYQVSLNSG-SHFCGGSLINSQWVVSAAHCYKSRIQVRLG 59 Query: 82 SDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139 + + Q I A+K HP ++ T ND+ML+KL+S A L+S V V LP C Sbjct: 60 EHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATVSLPRSCAA 119 Query: 140 PGTTCTVSGWGTTT 153 GT C +SGWG T Sbjct: 120 AGTECLISGWGNTK 133 >3H7T-A nrPDB Length = 235 Score = 181 bits (459), Expect = 4e-46, Method: Composition-based stats. Identities = 62/232 (26%), Positives = 103/232 (44%), Gaps = 16/232 (6%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDTL 85 II G PW V +L + CGG ++ +V+TAA C K ++ ++H GS + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGS-SY 59 Query: 86 GDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSS-MVKKVRLPS--RCEPPGT 142 + + A K + Y T N+ +++ +L KK+ LPS P T Sbjct: 60 RTTKGTSVMAKKIYI-VRYHPLTMQNNYAVIETEMPIKLDDKTTKKIELPSLLYDPEPDT 118 Query: 143 TCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKD-----LLENSMLCAGIPDSK 197 + VSGWG+T + + DLM + ++ + C + YK + + + CAG + Sbjct: 119 SVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYIYDGVFCAGGEYDE 178 Query: 198 KNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 GD+G P V GTL G+ S+ + P V+ +V + I D + Sbjct: 179 TYIGYGDAGDPAVQNGTLVGVASYISSM--PSEFPSVFLRVGYYVLDIKDII 228 >3H7O-A nrPDB Length = 228 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 61/231 (26%), Positives = 99/231 (42%), Gaps = 16/231 (6%) Query: 32 DGAPCARGSHPWQVALLS---GNQLHCGGVLVNERWVLTAAHC----KMNEYTVHLGSDT 84 G PW VA+ + L CGG ++++ +VLTAAHC K + S Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 85 LGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV-KKVRLPSRCEPP--G 141 L + + Y +T ND+ +++L+ +L + K +LP P G Sbjct: 62 LWEDPGKSDPYVSHVYLSFYRQETMENDIAILELSRPLKLDGLKSKPAKLPDIEFRPKTG 121 Query: 142 TTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY-KDLLENSMLCAGIPDSKKNA 200 + VSG+G + D DL + ++ +C Y L + CA + Sbjct: 122 SDVLVSGYGDGQTMDPK-DHDLKSAQLTVVDLDECRTKYGPIFLSLQVFCA--QKVGVSL 178 Query: 201 CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 +GD+G P V + TL G+ ++ FP P V+T+V + WI D +KK Sbjct: 179 ESGDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDIIKK 227 >1M9U-A nrPDB Length = 241 Score = 170 bits (432), Expect = 4e-43, Method: Composition-based stats. Identities = 68/242 (28%), Positives = 101/242 (41%), Gaps = 25/242 (10%) Query: 30 IIDGAPCARGSHPWQVALLSGN---QLHCGGVLVNERWVLTAAHCK----MNEYTVHLGS 82 +I G + G PWQ++ + CG L++ L+A+HC N V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 83 DTLGDRRA-QRIKASKSFRHPGYSTQT--HVNDLMLVKLNSQARLSSMVKKVRLP--SRC 137 D Q H Y T + ND+ ++ L + L ++ LP + Sbjct: 61 WQQSDTSGTQTANVDSYTMHENYGAGTASYSNDIAILHLATSISLGGNIQAAVLPANNNN 120 Query: 138 EPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDL----LENSMLCAGI 193 + GTTC +SGWG T + P L + +I+ CT + + ++ +C Sbjct: 121 DYAGTTCVISGWGRTDGTN-NLPDILQKSSIPVITTAQCTAAMVGVGGANIWDNHICVQD 179 Query: 194 PDSKKNACNGDSGGPLVCRG---TLQGLVSW----GTFPCGQPNDPGVYTQVCKFTKWIN 246 P ACNGDSGGPL C + G+ SW G C P+ P VYT+V + WI Sbjct: 180 PAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVYTRVSAYLGWIG 238 Query: 247 DT 248 D Sbjct: 239 DN 240 >3F1S-B nrPDB Length = 283 Score = 159 bits (404), Expect = 7e-40, Method: Composition-based stats. Identities = 49/220 (22%), Positives = 80/220 (36%), Gaps = 21/220 (9%) Query: 42 PWQVAL-LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSD-TLGDRRAQRIKASKSF 99 PWQV L S + CGGV++ E +VLT A C + + + + + IK + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVH 124 Query: 100 RHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP-----PGTTCTVSGWGTTTS 154 H Y NDL L++L + V P + P T +SGW Sbjct: 125 VHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWAR--- 181 Query: 155 PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG-----DSGGPL 209 + L V L+ ++C +V + C + + +G + G Sbjct: 182 NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSW 241 Query: 210 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 G L G+ P G + T+V +++ W M Sbjct: 242 FLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 >3H5C-B nrPDB Length = 317 Score = 157 bits (397), Expect = 5e-39, Method: Composition-based stats. Identities = 49/220 (22%), Positives = 80/220 (36%), Gaps = 21/220 (9%) Query: 42 PWQVAL-LSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSD-TLGDRRAQRIKASKSF 99 PWQV L S + CGGV++ E +VLT A C + + + + + IK + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVH 165 Query: 100 RHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP-----PGTTCTVSGWGTTTS 154 H Y NDL L++L + V P + P T +SGW Sbjct: 166 VHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWAR--- 222 Query: 155 PDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNG-----DSGGPL 209 + L V L+ ++C +V + C + + +G + G Sbjct: 223 NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMDGSVVTREHRGSW 282 Query: 210 VCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249 G L G+ P G + T+V +++ W M Sbjct: 283 FLTGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >1AKS-B nrPDB Length = 98 Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats. Identities = 42/99 (42%), Positives = 59/99 (59%), Gaps = 1/99 (1%) Query: 154 SPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRG 213 S ++PS L C+ ++S C Y + +M+C G K++C GDSGGP+VC G Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 214 TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 LQG+VSWG + C Q N PGVYT+VC + WI T+ + Sbjct: 61 QLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >3VGC-B nrPDB Length = 131 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 52/131 (39%), Positives = 72/131 (54%), Gaps = 6/131 (4%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHL-GSDTLGD 87 I++G GS PWQV+L H CGG L+NE WV+TAAHC + V + G G Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 88 RRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCE--PPGTT 143 Q++K +K F++ Y++ T ND+ L+KL++ A S V V LPS + GTT Sbjct: 61 SSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTT 120 Query: 144 CTVSGWGTTTS 154 C +GWG T Sbjct: 121 CVTTGWGLTRY 131 >2I6S-A nrPDB Length = 517 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 55/242 (22%), Positives = 102/242 (42%), Gaps = 47/242 (19%) Query: 31 IDGAPCARGSH---PWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGD 87 + PW V + +Q C G L++++WVLTAAHC + L +GD Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 289 Query: 88 RRAQ---RIKASKSFRHPGYST---------QTHVNDLMLVKLNSQARLSSMVKKVRLPS 135 ++Q K+ PG+ + + +D+ L+KL + ++S+ + + LP Sbjct: 290 PKSQWGKEFLIEKAVISPGFDVFAKKNQGILEFYGDDIALLKLAQKVKMSTHARPICLPC 349 Query: 136 RCE-------PPGTTCT-----VSGWGTTTSPDVTFPSDLMCVDVKL-ISPQDCTKV--- 179 E P G+TC + + + V + +++K+ + C +V Sbjct: 350 TMEANLALRRPQGSTCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSCAEVVSQ 409 Query: 180 ----------YKDLLENSMLCAGIPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTF- 224 ++++ + LC+G + ++ C G+SGG + R GLVSWG + Sbjct: 410 EKTMFPNLTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLVSWGLYN 468 Query: 225 PC 226 PC Sbjct: 469 PC 470 >2JET-B nrPDB Length = 128 Score = 147 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 49/128 (38%), Positives = 67/128 (52%), Gaps = 6/128 (4%) Query: 33 GAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHCKMNEYTVHL-GSDTLGDRRA 90 G GS PWQV+L H CGG L++E WV+TAAHC + V + G G Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 91 --QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLP--SRCEPPGTTCTV 146 Q +K ++ F++P ++ T ND+ L+KL + A+ S V V LP PPGT C Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVRNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGTVCAT 120 Query: 147 SGWGTTTS 154 +GWG T Sbjct: 121 TGWGKTKY 128 >2WIN-I nrPDB Length = 507 Score = 145 bits (366), Expect = 2e-35, Method: Composition-based stats. Identities = 54/240 (22%), Positives = 88/240 (36%), Gaps = 48/240 (20%) Query: 39 GSHPWQVALL----SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK 94 PWQ + S C G +V+E +VLTAAHC + H ++G + ++ Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG-GEKRDLE 290 Query: 95 ASKSFRHPGYS---------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC-------E 138 HP Y+ + + D+ L+KL ++ + ++ + LP Sbjct: 291 IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRL 350 Query: 139 PPGTTCTVSGWGTTTSPDVTF------PSDLMCVDVKLISPQD---CT------------ 177 PP TTC + D+ L +V + + C Sbjct: 351 PPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKV 410 Query: 178 KVYKDLLENSMLCAG--IPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPND 231 K +++ LC G P + N C GDSGGPL+ R G++SWG + Sbjct: 411 KDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQK 470 >1DLE-A nrPDB Length = 298 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 54/240 (22%), Positives = 88/240 (36%), Gaps = 48/240 (20%) Query: 39 GSHPWQVALL----SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK 94 PWQ + S C G +V+E +VLTAAHC + H ++G + ++ Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG-GEKRDLE 83 Query: 95 ASKSFRHPGYS---------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC-------E 138 HP Y+ + + D+ L+KL ++ + ++ + LP Sbjct: 84 IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRL 143 Query: 139 PPGTTCTVSGWGTTTSPDVTF------PSDLMCVDVKLISPQD---CT------------ 177 PP TTC + D+ L +V + + C Sbjct: 144 PPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKV 203 Query: 178 KVYKDLLENSMLCAG--IPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPND 231 K +++ LC G P + N C GDSGGPL+ R G++SWG + Sbjct: 204 KDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQK 263 >1RIW-B nrPDB Length = 147 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 46/147 (31%), Positives = 66/147 (44%), Gaps = 21/147 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVKKVRL 133 V +G T +R ++I K + HP Y+ + D+ L+KL S + V L Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCL 120 Query: 134 PSRC-----EPPGTTCTVSGWGTTTSP 155 P R G V+GWG Sbjct: 121 PDRETAASLLQAGYKGRVTGWGNLKET 147 >2OK5-A nrPDB Length = 752 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 54/240 (22%), Positives = 88/240 (36%), Gaps = 48/240 (20%) Query: 39 GSHPWQVALL----SGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIK 94 PWQ + S C G +V+E +VLTAAHC + H ++G + ++ Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVG-GEKRDLE 534 Query: 95 ASKSFRHPGYS---------TQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC-------E 138 HP Y+ + + D+ L+KL ++ + ++ + LP Sbjct: 535 IEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRL 594 Query: 139 PPGTTCTVSGWGTTTSPDVTF------PSDLMCVDVKLISPQD---CT------------ 177 PP TTC + D+ L +V + + C Sbjct: 595 PPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKV 654 Query: 178 KVYKDLLENSMLCAG--IPDSKKNACNGDSGGPLVC----RGTLQGLVSWGTFPCGQPND 231 K +++ LC G P + N C GDSGGPL+ R G++SWG + Sbjct: 655 KDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQK 714 >1BBR-H nrPDB Length = 150 Score = 139 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 21/147 (14%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G G PWQV L S +L CG L+++RWVLTAAHC + ++ Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 78 VHLGSD--TLGDRRAQRIKA-SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVKKVRL 133 V +G T +R+ ++I K + HP Y+ + D+ L+KL LS + V L Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWKENLDRDIALLKLKRPIELSDYIHPVCL 120 Query: 134 PSRCEP-----PGTTCTVSGWGTTTSP 155 P + G V+GWG Sbjct: 121 PDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2HNT-F nrPDB Length = 105 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 10/103 (9%) Query: 159 FPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI---PDSKKNACNGDSGGPLVC---- 211 PS L V++ ++ C + + ++M CAG + +AC GDSGGP V Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 212 --RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 R G+VSWG C + G YT V + KWI + + Sbjct: 62 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVIDQF 103 >1BBR-E nrPDB Length = 109 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 159 FPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGI---PDSKKNACNGDSGGPLVC---- 211 PS L V++ L+ C + + ++M CAG + +AC GDSGGP V Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 212 --RGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKK 251 R G+VSWG C + G YT V + KWI + + Sbjct: 66 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVIDR 106 >2KAI-A nrPDB Length = 80 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 38/78 (48%), Positives = 47/78 (60%), Gaps = 2/78 (2%) Query: 30 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--GD 87 II G C + SHPWQVA+ + CGGVLVN +WVLTAAHCK + Y V LG L + Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 88 RRAQRIKASKSFRHPGYS 105 AQ + F HPG++ Sbjct: 61 NTAQFFGVTADFPHPGFN 78 >3RU4-E nrPDB Length = 96 Score = 116 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 7/99 (7%) Query: 158 TFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCR----G 213 P L + L+S +C K + ++++M+CAG ++C GDSGGPLVC+ Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAW 58 Query: 214 TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 TL G+VSWG+ C + PGVY +V W+ T+ + Sbjct: 59 TLVGIVSWGSSTCST-STPGVYARVTALVNWVQQTLAAN 96 >2JET-C nrPDB Length = 99 Score = 114 bits (285), Expect = 4e-26, Method: Composition-based stats. Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 7/99 (7%) Query: 158 TFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCR----G 213 P L + ++S DC K + + + M CAG ++C GDSGGPLVC+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGAS--GVDSCMGDSGGPLVCQKDGVW 61 Query: 214 TLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKH 252 TL G+VSWG+ C + PGVY++V W+ ++ + Sbjct: 62 TLAGIVSWGSGVCST-STPGVYSRVTALMPWVQQILEAN 99 >1EPT-B nrPDB Length = 82 Score = 110 bits (275), Expect = 8e-25, Method: Composition-based stats. Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 2/82 (2%) Query: 74 NEYTVHLGSDTLG--DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKV 131 + V LG + + Q I A+K HP ++ T ND+ML+KL+S A L+S V V Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFNGNTLDNDIMLIKLSSPATLNSRVATV 60 Query: 132 RLPSRCEPPGTTCTVSGWGTTT 153 LP C GT C +SGWG T Sbjct: 61 SLPRSCAAAGTECLISGWGNTK 82 >2HNT-E nrPDB Length = 81 Score = 76.0 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 25/66 (37%), Gaps = 6/66 (9%) Query: 96 SKSFRHPGYST-QTHVNDLMLVKLNSQARLSSMVKKVRLPSRC-----EPPGTTCTVSGW 149 K + HP Y+ + D+ L+KL S + V LP R G V+GW Sbjct: 9 EKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGW 68 Query: 150 GTTTSP 155 G Sbjct: 69 GNLKET 74 >2HNT-C nrPDB Length = 70 Score = 73.3 bits (179), Expect = 9e-14, Method: Composition-based stats. Identities = 25/67 (37%), Positives = 36/67 (53%), Gaps = 12/67 (17%) Query: 30 IIDGAPCARGSHPWQVALL--SGNQLHCGGVLVNERWVLTAAHCKM----------NEYT 77 I++G+ G PWQV L S +L CG L+++RWVLTAAHC + N+ Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 78 VHLGSDT 84 V +G + Sbjct: 61 VRIGKHS 67 >1P3E-A nrPDB Length = 215 Score = 39.0 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 12/114 (10%) Query: 45 VALLSGNQLHCGGVLVNERWVLTAAHCKMNEY--------TVHLGSDTLGDRRAQRIKAS 96 +A ++ C G L+ +LT HC N +V+ G + + Sbjct: 22 IAYITFGGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGS-ANMT 80 Query: 97 KSFRHPGY-STQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGW 149 + + GY +T D ++K ++ + + V + GTT +SG+ Sbjct: 81 EFYVPSGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNLTGTTIKISGY 132 >2OUA-A nrPDB Length = 188 Score = 37.9 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 51/178 (28%), Gaps = 53/178 (29%) Query: 66 LTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLS 125 +TA HC V +G + + F ND V+ S L+ Sbjct: 31 VTAGHCGSVGTQVSIG-------NGRGVFERSVFP---------GNDAAFVRGTSNFTLT 74 Query: 126 SMV--------KKVRLPSRCEPPGTTCT---VSGW--GTTTSPDVTFPSDLMCVDVKLIS 172 ++V V S C +GW GT + + V Sbjct: 75 NLVSRYNSGGYATVSGSSTAPIGSQVCRSGSTTGWYCGTIQARN-------QTVSYP--- 124 Query: 173 PQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPN 230 + L + +CA GDSGG + QG+ S G+ C Sbjct: 125 -----QGTVHSLTRTSVCAEP---------GDSGGSFISGTQAQGVTSGGSGNCRTGG 168 >5ILB-A nrPDB Length = 474 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 26/83 (31%), Gaps = 13/83 (15%) Query: 34 APCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRI 93 S PWQ ++ + +LT AHC ++ V + R R Sbjct: 17 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVK-----VKRRGDDRK 69 Query: 94 KASKSFRHPGYSTQTHVNDLMLV 116 +K + D+ L+ Sbjct: 70 YVAKVLV------RGVDCDIALL 86 >4FLN-A nrPDB Length = 539 Score = 36.7 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 26/83 (31%), Gaps = 13/83 (15%) Query: 34 APCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRI 93 S PWQ ++ + +LT AHC ++ V + R R Sbjct: 57 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVK-----VKRRGDDRK 109 Query: 94 KASKSFRHPGYSTQTHVNDLMLV 116 +K + D+ L+ Sbjct: 110 YVAKVLV------RGVDCDIALL 126 >2EA3-A nrPDB Length = 189 Score = 36.3 bits (83), Expect = 0.012, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 14/28 (50%) Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPN 230 GDSGG L+ QG+ S G+ C Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGG 162 >2PFE-A nrPDB Length = 186 Score = 36.3 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPN 230 GDSGGP + QG+ S GT C Sbjct: 138 GDSGGPWLTGSQAQGVTSGGTGDCRSGG 165 >2SFA-A nrPDB Length = 191 Score = 34.0 bits (77), Expect = 0.062, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 13/28 (46%) Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPN 230 GDSGG L T GL S G+ C Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGG 172 >2SGA-A nrPDB Length = 181 Score = 33.6 bits (76), Expect = 0.078, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 13/28 (46%) Query: 203 GDSGGPLVCRGTLQGLVSWGTFPCGQPN 230 GDSGG L T GL S G+ C Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGG 162 >3LT3-A nrPDB Length = 217 Score = 33.3 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 26/164 (15%), Positives = 53/164 (32%), Gaps = 28/164 (17%) Query: 57 GVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLV 116 G +++ V+T AH V GS+ + + + Y D+ ++ Sbjct: 42 GFVISPDRVMTNAH-------VVAGSNNVTVYAGDKPFEATVV---SYDPSV---DVAIL 88 Query: 117 KLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC 176 A + + G V G+ P+ + ++L P Sbjct: 89 -----AVPHLPPPPLVFAAEPAKTGADVVVLGY-PGGGNFTATPARIREA-IRLSGPDIY 141 Query: 177 TKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLV-CRGTLQGLV 219 + + + + + GD+GGPL+ G + G+V Sbjct: 142 GD--PEPVTRDVY-----TIRADVEQGDAGGPLIDLNGQVLGVV 178 >3H7V-A nrPDB Length = 330 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 28/88 (31%), Gaps = 6/88 (6%) Query: 66 LTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLS 125 LT A + G + ++ + PG+ ++T D+ L + L+ Sbjct: 16 LTTA---QGVWRSRSGIYLRLEDEQGQVGYGEIAPLPGWGSETLNADIALCQ-QLPGHLT 71 Query: 126 SMVKKVRLPSRCEPPGTTCTVSGWGTTT 153 + +P P + W + Sbjct: 72 PEIM-ATIPEA-LPAAQFGFATAWQSVG 97 >5MRT-A nrPDB Length = 205 Score = 31.3 bits (70), Expect = 0.36, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 19/46 (41%), Gaps = 10/46 (21%) Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLV-CRGTLQGLVSWGTFPCGQ 228 L + C G GDSGG + G QGL S G P GQ Sbjct: 137 LTRANNCTG---------RGDSGGSWITAAGQAQGLTSGGNLPAGQ 173 >1DUE-A nrPDB Length = 242 Score = 30.6 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 22/150 (14%), Positives = 46/150 (30%), Gaps = 29/150 (19%) Query: 16 LALETAGEEAQGDKIIDGAPCARGSHPWQV--ALLSGNQLHCGGVLVNERWVLTAAHC-- 71 L E + + D+ +P+ + Q GVL+ + VLT H Sbjct: 25 LPKELFSKVDEKDR---------QKYPYNTIGNVFVKGQTSATGVLIGKNTVLTNRHIAK 75 Query: 72 ------KMNEYTVHLGSDTLGDRRAQ--RIKASKSFRHPGYSTQTHVNDLMLVKLNSQ-- 121 + + +D G+ + + + P DL L++L Sbjct: 76 FANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEP----FGAGVDLALIRLKPDQN 131 Query: 122 -ARLSSMVKKVRLPSRCE-PPGTTCTVSGW 149 L + ++ + + G + G+ Sbjct: 132 GVSLGDKISPAKIGTSNDLKDGDKLELIGY 161 >5UBM-B nrPDB Length = 152 Score = 30.6 bits (68), Expect = 0.69, Method: Composition-based stats. Identities = 4/18 (22%), Positives = 8/18 (44%) Query: 7 LPLQILLLSLALETAGEE 24 LP + + + E E+ Sbjct: 134 LPKCVPVCGVPREPFEEK 151 >5JYK-A nrPDB Length = 566 Score = 30.2 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 40 SHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHL 80 S PWQ + G ++ R VLT AH + V L Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKL 153 >5ILA-A nrPDB Length = 301 Score = 29.8 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 17/41 (41%), Gaps = 2/41 (4%) Query: 40 SHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHL 80 S PWQ + G ++ R VLT AH + V L Sbjct: 115 SLPWQRKRQYSSGS--SGFIIGGRRVLTNAHSVEHHTQVKL 153 >5MRR-A nrPDB Length = 199 Score = 29.4 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 23/57 (40%), Gaps = 10/57 (17%) Query: 197 KKNAC--NGDSGGPLVCR-GTLQGLVSWGTFP-----CGQP--NDPGVYTQVCKFTK 243 + NAC GDSGG G QG++S G CG P ++ +V Sbjct: 134 QGNACMGRGDSGGSWFTSAGQAQGVMSGGNVQSNGNNCGIPASQRSSLFERVGPILS 190 >4I6M-A nrPDB Length = 477 Score = 29.4 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 18/38 (47%) Query: 78 VHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLML 115 + GS +L + QRI S R P Y T N +M+ Sbjct: 393 IITGSTSLIEGMEQRIIKELSIRFPQYKLTTFANQVMM 430 >1HPG-A nrPDB Length = 187 Score = 29.0 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 54/174 (31%), Gaps = 42/174 (24%) Query: 61 NERWVLTAAHCKM--NEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKL 118 R+ +TA HC ++ G +G R SF Y + + Sbjct: 24 GARYFVTAGHCTNISANWSASSGGSVVGVREG------TSFPTNDYGIVRYTDG------ 71 Query: 119 NSQAR----LSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQ 174 +S A + + + + G SG S + V+V + Sbjct: 72 SSPAGTVDLYNGSTQDIS-SAANAVVGQAIKKSG-----STTKVTSGTVTAVNVTV---- 121 Query: 175 DCTKVYKDLLENSMLCAGIPDSKKNACN--GDSGGPLVCRGTLQGLVSWGTFPC 226 Y D +M+ + AC+ GDSGG G+ S G+ C Sbjct: 122 ----NYGDGPVYNMV-------RTTACSAGGDSGGAHFAGSVALGIHS-GSSGC 163 >4FVB-A nrPDB Length = 152 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 14/23 (60%) Query: 203 GDSGGPLVCRGTLQGLVSWGTFP 225 GD+GG L C+ + G+VS G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >3W95-A nrPDB Length = 171 Score = 29.0 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 10/23 (43%), Positives = 14/23 (60%) Query: 203 GDSGGPLVCRGTLQGLVSWGTFP 225 GD+GG L C+ + G+VS G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >2M5T-A nrPDB Length = 142 Score = 29.0 bits (64), Expect = 2.1, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 25/50 (50%), Gaps = 7/50 (14%) Query: 177 TKVYKDLLENSMLCAGIPDSKKNACN-GDSGGPLVCRGTLQGLVSWGTFP 225 T+ Y ++ ++L + C GD+GG L+CR + G+++ G Sbjct: 82 TQYYPKHIQYNLL------IGEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >1GBE-A nrPDB Length = 198 Score = 29.0 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 16/38 (42%), Gaps = 10/38 (26%) Query: 184 LENSMLCAGIPDSKKNACNGDSGGPLVCR-GTLQGLVS 220 L CAG GDSGG + G QG++S Sbjct: 131 LTQGNACAG---------RGDSGGSWITSAGQAQGVMS 159 >2HRV-A nrPDB Length = 142 Score = 28.6 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 24/47 (51%), Gaps = 7/47 (14%) Query: 177 TKVYKDLLENSMLCAGIPDSKKNACN-GDSGGPLVCRGTLQGLVSWG 222 ++ Y ++ ++L + C GD GG L+C+ + G+V+ G Sbjct: 83 SEYYPKHIQYNLL------IGEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >6HQA-B nrPDB Length = 722 Score = 28.6 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 87 DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRC 137 D + + + P S Q ND+ +++ +S+A++ + LPS C Sbjct: 333 DPSDENNPSKDTLPLPLKSAQDLRNDIAMIQ-DSRAKIKLSAAQASLPSVC 382 >4B6E-A nrPDB Length = 683 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 11/18 (61%), Gaps = 1/18 (5%) Query: 202 NGDSGGPLVC-RGTLQGL 218 G SGGPL+C G G+ Sbjct: 171 KGSSGGPLLCPSGHAVGI 188 >6FE6-A nrPDB Length = 165 Score = 26.7 bits (58), Expect = 9.1, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 11/18 (61%), Gaps = 1/18 (5%) Query: 202 NGDSGGPLVC-RGTLQGL 218 G SGGPL+C G G+ Sbjct: 115 KGSSGGPLLCPSGHAVGI 132 >4U01-A nrPDB Length = 203 Score = 26.7 bits (58), Expect = 9.8, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 11/18 (61%), Gaps = 1/18 (5%) Query: 202 NGDSGGPLVC-RGTLQGL 218 G SGGPL+C G G+ Sbjct: 137 KGSSGGPLLCPSGHAVGI 154 >4K8B-A nrPDB Length = 181 Score = 26.7 bits (58), Expect = 9.9, Method: Composition-based stats. Identities = 9/18 (50%), Positives = 11/18 (61%), Gaps = 1/18 (5%) Query: 202 NGDSGGPLVC-RGTLQGL 218 G SGGPL+C G G+ Sbjct: 136 KGSSGGPLLCPSGHAVGI 153 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.158 0.562 Lambda K H 0.267 0.0486 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,592,663 Number of Sequences: 36641 Number of extensions: 510928 Number of successful extensions: 2603 Number of sequences better than 10.0: 192 Number of HSP's better than 10.0 without gapping: 331 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 1025 Number of HSP's gapped (non-prelim): 375 length of query: 253 length of database: 10,336,785 effective HSP length: 95 effective length of query: 158 effective length of database: 6,855,890 effective search space: 1083230620 effective search space used: 1083230620 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.7 bits)