BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P49770 (351 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6O81-C nrPDB 719 0.0 6JLZ-C nrPDB 237 4e-63 6I3M-E nrPDB 174 6e-44 6O85-G nrPDB 94 8e-20 6I3M-A nrPDB 89 4e-18 6O85-E nrPDB 88 6e-18 3A9C-A nrPDB 86 2e-17 5YG5-A nrPDB 84 9e-17 1VB5-A nrPDB 74 1e-13 5B04-G nrPDB 72 3e-13 5B04-A nrPDB 72 5e-13 1T5O-A nrPDB 67 1e-11 1T9K-A nrPDB 66 2e-11 6A34-A nrPDB 65 4e-11 6I7T-C nrPDB 65 6e-11 2YRF-A nrPDB 63 2e-10 4LDQ-A nrPDB 59 4e-09 5DBO-A nrPDB 52 3e-07 2A0U-A nrPDB 51 9e-07 3CQ0-A nrPDB 32 0.53 3E8J-A nrPDB 32 0.60 5NNB-A nrPDB 31 0.91 5KUF-A nrPDB 30 1.9 5KUH-A nrPDB 30 2.2 3FLU-A nrPDB 28 5.1 5W61-A nrPDB 28 7.4 4JWP-A nrPDB 28 8.4 4BD6-A nrPDB 28 8.5 >6O81-C nrPDB Length = 368 Score = 719 bits (1857), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/350 (100%), Positives = 350/350 (100%) Query: 2 PGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELI 61 PGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELI Sbjct: 19 PGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELI 78 Query: 62 RREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNED 121 RREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNED Sbjct: 79 RREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNED 138 Query: 122 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA 181 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA Sbjct: 139 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA 198 Query: 182 ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA 241 ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA Sbjct: 199 ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA 258 Query: 242 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD 301 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD Sbjct: 259 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD 318 Query: 302 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 351 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL Sbjct: 319 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 368 >6JLZ-C nrPDB Length = 399 Score = 237 bits (605), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 107/225 (47%), Positives = 164/225 (72%), Gaps = 2/225 (0%) Query: 129 LQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFH 188 +++ II I +++ EL+ +I Q+++H+HSNE+I+T G S+TVEAFL+ AA+KRKF Sbjct: 175 MRAVIISGIQDVIDELDKINTDIEVQSMDHLHSNEIILTQGCSKTVEAFLRFAAKKRKFS 234 Query: 189 VIVAECAPFCQ--GHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALR 246 VIVAE P Q H MA L++AGI+TTV++DA IFA+MSRVNKVI+GT IL NG L Sbjct: 235 VIVAEGFPNNQKGSHAMAKRLAQAGIDTTVISDATIFAIMSRVNKVILGTHAILGNGGLV 294 Query: 247 AVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKV 306 +G +A AA+HH+TP++VC+ ++KLSP +P + +S + +P++++ F EGD++ + Sbjct: 295 TYSGAQLVAQAARHHATPVVVCSGIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISRA 354 Query: 307 SVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 351 + P +DY+PP+L+ LFI+N+GG PSY+YR+M++ Y D +L Sbjct: 355 EILNPYYDYIPPDLVDLFITNLGGYPPSYLYRIMNDTYDASDTIL 399 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 34/93 (36%), Positives = 59/93 (63%), Gaps = 5/93 (5%) Query: 15 IESFVETLK--RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQ 72 + S + LK + GP + +A ET ++RQ+I+ RWS +L++ +R G + AQ Sbjct: 19 VSSLIADLKSRKVQGPFA---VAVETALVMRQVISQTRWSTVDQLIDTVRAVGSTLVKAQ 75 Query: 73 PSETTVGNMVRRVLKIIREEYGRLHGRSDESDQ 105 P+E + GN++RR+L++IREEY L +DE+++ Sbjct: 76 PTEFSCGNIIRRILRLIREEYQELLKTADENEK 108 >6I3M-E nrPDB Length = 381 Score = 174 bits (441), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 118/367 (32%), Positives = 195/367 (53%), Gaps = 30/367 (8%) Query: 6 AKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREG 65 A S+++ I++FV LKR + S +A ETL LL + I+ RW++ +L+E IR G Sbjct: 13 AATSDVNVTIDTFVAKLKRRQ-VQGSYAIALETLQLLMRFISAARWNHVNDLIEQIRDLG 71 Query: 66 RRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSD------------------ESDQQE 107 + A P+ + GN++RR+L ++R+E + + +Q Sbjct: 72 NSLEKAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQP 131 Query: 108 SLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMT 167 ++ +SG + Y Q+ I+ I +L+ E++ E I A++ IH +E+++T Sbjct: 132 HQNRKNSSGSSSMKTKTDYRQVA---IQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLT 188 Query: 168 -IGFSRTVEAFLKEAARK--RKFHVIVAECAP--FCQGHEMAVNLSKAGIETTVMTDAAI 222 S+TV FL A + R F V+V E P HE A L++ IET V+ D+A+ Sbjct: 189 PTPDSKTVLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAV 248 Query: 223 FAVMSRVNKVIIGTKTILANGA-LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNE 281 FA+MSRV KVIIGTK + NG + + +G ++ A+ TP+ A ++KLSP +P + Sbjct: 249 FALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFD 308 Query: 282 EDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMS 341 + F +F + +LP D +++ + DYVPPE I ++I+N+GG PS+IYR+ Sbjct: 309 VEKFVEFGGSQRILP--RMDPRKRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAW 366 Query: 342 ELYHPDD 348 + Y D Sbjct: 367 DNYKQID 373 >6O85-G nrPDB Length = 305 Score = 94.0 bits (232), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 70/223 (31%), Positives = 108/223 (48%), Gaps = 8/223 (3%) Query: 126 YAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-ARK 184 Y++ + +IE L + + IA I I+T +SR V L+ A A K Sbjct: 86 YSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAK 145 Query: 185 RKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGA 244 ++F V V E P G +MA L + TV+ DAA+ +M + + VI+G + ++ NG Sbjct: 146 KRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGG 205 Query: 245 LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFP-NEEDSFHKFVAPEEVLPF--TEGD 301 + GT+ +A+ AK + P V A FK FP N++D KF + L T D Sbjct: 206 IINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQD 265 Query: 302 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELY 344 + E+ H P DY P LITL +++G PS + + +LY Sbjct: 266 LKEE---H-PWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLY 304 >6I3M-A nrPDB Length = 305 Score = 88.6 bits (218), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 57/197 (28%), Positives = 100/197 (50%), Gaps = 6/197 (3%) Query: 151 IAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKR-KFHVIVAECAPFCQGHEMAVNLSK 209 IA ++ I +++I+ G+SR V + L AA K +F +V E P QG+++ L + Sbjct: 112 IAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQ 171 Query: 210 AGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCA 269 GI T++ D+A+ AV+ +V+KV +G + + +G + + GT+++ + A + P V Sbjct: 172 KGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVT 231 Query: 270 PMFKLSPQFPNEEDSFHKFVAPEEVLPFT-EGDILEKVSVHCPVFDYVPPELITLFISNI 328 K FP D P L FT D LE ++ P DY E IT I+++ Sbjct: 232 ESHKFVRMFPLSSDDLPMAGPP---LDFTRRTDDLED-ALRGPTIDYTAQEYITALITDL 287 Query: 329 GGNAPSYIYRLMSELYH 345 G PS + + ++++ Sbjct: 288 GVLTPSAVSEELIKMWY 304 >6O85-E nrPDB Length = 523 Score = 87.8 bits (216), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 116/235 (49%), Gaps = 23/235 (9%) Query: 109 LHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQAL-----EHIHSNE 163 L+K +TS G ++ ++L++ I + E +V +AAQA+ + I + + Sbjct: 280 LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIV--------LAAQAISRFAYQKISNGD 331 Query: 164 VIMTIGFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAI 222 VI+ G S V L+EA R+F V+V + P+ +G +L AG+ + + A Sbjct: 332 VILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAA 391 Query: 223 FAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEE 282 V+ V+KV++G +LANG++ + GT LAL A+ H+ P++VC +K + + Sbjct: 392 SYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDA 451 Query: 283 DSFHKFVAPEEVLPFTEGD--ILEKVSVHCP------VFDYVPPELITLFISNIG 329 ++ P++ L G+ L H V+D PPEL+ L I+ +G Sbjct: 452 FVSNELDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 505 >3A9C-A nrPDB Length = 338 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 64/204 (31%), Positives = 93/204 (45%), Gaps = 2/204 (0%) Query: 128 QLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRK- 186 QL+ II A E + E +E I + I +VIMT S+ + +K A + K Sbjct: 108 QLRFVIINAAKEFIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGKD 167 Query: 187 FHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALR 246 VIV E P QG A L+ GI + D+A M +KV++G +I NGA+ Sbjct: 168 IKVIVTETRPKWQGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVI 227 Query: 247 AVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEK- 305 GT +AL AK H ++ A +K P+ + + P EV+P E K Sbjct: 228 NKIGTALIALTAKEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKN 287 Query: 306 VSVHCPVFDYVPPELITLFISNIG 329 + V P FD PPE + + I+ G Sbjct: 288 IEVWNPAFDVTPPEYVDVIITERG 311 >5YG5-A nrPDB Length = 324 Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 62/203 (30%), Positives = 93/203 (45%), Gaps = 2/203 (0%) Query: 129 LQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRK-F 187 L+ I + E + E +E I + I ++IMT S+ + +K+A + K Sbjct: 95 LRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAAISVMKKAFEQGKNI 154 Query: 188 HVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRA 247 VIV E P QG A L+ GI + D+A M +KV++G +I ANGA+ Sbjct: 155 KVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVVMGADSITANGAVIN 214 Query: 248 VTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEK-V 306 GT +AL AK H +++ A +K P + + P EV+P E K + Sbjct: 215 KIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTEVIPEEELRTWPKNI 274 Query: 307 SVHCPVFDYVPPELITLFISNIG 329 V P FD PPE I + I+ G Sbjct: 275 EVWNPAFDVTPPEYIDVIITERG 297 >1VB5-A nrPDB Length = 276 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 55/196 (28%), Positives = 89/196 (45%), Gaps = 12/196 (6%) Query: 139 ELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAA-RKRKFHVIVAECAPF 197 E L +E +A+ + I +VI+T FS TV ++ A RK++F VI+ E +P Sbjct: 87 EFLRRMEEAKRELASIGAQLIDDGDVIITHSFSSTVLEIIRTAKERKKRFKVILTESSPD 146 Query: 198 CQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALA 257 +G +A L +GIE V+TDA + + I+G I +G + GT+ LALA Sbjct: 147 YEGLHLARELEFSGIEFEVITDAQMGLFCREASIAIVGADMITKDGYVVNKAGTYLLALA 206 Query: 258 AKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVP 317 ++ P V A +K FH + +V+ I V + +FD P Sbjct: 207 CHENAIPFYVAAETYK-----------FHPTLKSGDVMLMERDLIRGNVRIRNVLFDVTP 255 Query: 318 PELITLFISNIGGNAP 333 + + I+ +G P Sbjct: 256 WKYVRGIITELGIVIP 271 >5B04-G nrPDB Length = 467 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 51/192 (26%), Positives = 87/192 (45%), Gaps = 13/192 (6%) Query: 151 IAAQALEHIHSNEVIMTIGFSRTVEAFLKEAAR-KRKFHVIVAECAPFCQGHEMAVNLSK 209 I A E I +VI+T S TV L A +KF V+V + P +G L++ Sbjct: 257 IVQAATEKIQDGDVILTYLHSSTVNDVLIHAKNVGKKFRVVVVDSRPEFEGRVCLKLLTE 316 Query: 210 AGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCA 269 GIE T + +A+ +M V K+ +G +L+NGAL + GT ++L + P+I C Sbjct: 317 HGIECTYVMISALSYIMQEVTKIFLGGHAMLSNGALYSRAGTSLISLLGHESNVPVIACC 376 Query: 270 PMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPV------------FDYVP 317 +K + + + +++ ++++ D EK V +D P Sbjct: 377 ESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFEEKPGVLANWKSVKNLKLLSLKYDVTP 436 Query: 318 PELITLFISNIG 329 P LIT+ + +G Sbjct: 437 PRLITVCVCEMG 448 >5B04-A nrPDB Length = 341 Score = 71.6 bits (174), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 64/225 (28%), Positives = 98/225 (43%), Gaps = 21/225 (9%) Query: 126 YAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKR 185 + Q + +++E + + IA I VI+T GFSR V A L AA++ Sbjct: 100 FEQCKRHLVENGKLFIQRARACRQRIAHLGYPLIRDGSVILTHGFSRGVAAVLLAAAKRH 159 Query: 186 -KFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGA 244 +F V V E P G M L A I T ++ D+A+ M+RV+ V++G + ++ NG Sbjct: 160 VRFKVFVTESRPSGSGCLMTRTLKNACIPTCMVLDSAVSFTMNRVDLVLVGAEGVVENGG 219 Query: 245 LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFP--NEEDSFHKFV------APEEVLP 296 L GT LA+ AKH P A K FP + F + + +PE V P Sbjct: 220 LINQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIPFSRPILEFDDPSPETVHP 279 Query: 297 FTEGDILEKVSVH------------CPVFDYVPPELITLFISNIG 329 E ++H P D PPE ++ I+++G Sbjct: 280 EPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVSGLITDLG 324 >1T5O-A nrPDB Length = 351 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 24/164 (14%) Query: 185 RKFHVIVAECAPFCQGHEMAV-NLSKAGIETTVMTDAAIFAVMSR--VNKVIIGTKTILA 241 ++ VI E P QG + L + GI+ T++TD+ + VM + V+KVI+G I+ Sbjct: 179 KEIRVIACETRPLNQGSRLTCWELMEDGIDVTLITDSMVGIVMQKGMVDKVIVGADRIVR 238 Query: 242 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLS----------PQFPNEEDSFHKFVAP 291 + + GT+T+++ AKHH+ P V AP + P EE F Sbjct: 239 DAVFNKI-GTYTVSVVAKHHNIPFYVAAPKATFDWERTAKDVVIEERPREE---LIFCGK 294 Query: 292 EEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSY 335 ++ P V V+ P FD P E +T I+ G P Y Sbjct: 295 RQIAPLN-------VKVYNPAFDPTPLENVTALITEYGVIYPPY 331 >1T9K-A nrPDB Length = 347 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 50/155 (32%), Positives = 72/155 (46%), Gaps = 4/155 (2%) Query: 185 RKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--VNKVIIGTKTILA 241 ++ V E P+ QG + A L K GIE V+TD +M R ++ V++G I Sbjct: 181 KRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKRGLIDAVVVGADRIAL 240 Query: 242 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD 301 NG GT++LA+ AK ++ P V AP+ + P + E+ + PEEV Sbjct: 241 NGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEERRPEEVTHCGGNR 300 Query: 302 IL-EKVSVHCPVFDYVPPELITLFISNIGGNAPSY 335 I E V V P FD LIT I+ G P + Sbjct: 301 IAPEGVKVLNPAFDVTENTLITAIITEKGVIRPPF 335 >6A34-A nrPDB Length = 364 Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 44/146 (30%), Positives = 69/146 (47%), Gaps = 3/146 (2%) Query: 193 ECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--VNKVIIGTKTILANGALRAVT 249 E P QG + A S G+ ++ D A VM + V+ +I+G I+ANG Sbjct: 200 ETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQGFVDAIIVGADRIVANGDFANKI 259 Query: 250 GTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVH 309 GT+ LA+ A+ H P AP+ + + + +D + +PEEVL I V V+ Sbjct: 260 GTYMLAVLAREHGIPFFAVAPLSSIDMELKSGKDIPIEERSPEEVLTCGGCRIAPDVPVY 319 Query: 310 CPVFDYVPPELITLFISNIGGNAPSY 335 P FD P + +T I++ G P + Sbjct: 320 NPAFDVTPHKYLTGIITDRGVVWPPF 345 >6I7T-C nrPDB Length = 651 Score = 64.7 bits (156), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 55/231 (23%), Positives = 101/231 (43%), Gaps = 30/231 (12%) Query: 68 MTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYA 127 + A+P T+GN +R +++E + D S ++ K D Sbjct: 330 LKKARPLSVTMGNAIRW----LKQEISLI----DPSTPDKAAKK---------DLCEKIG 372 Query: 128 QLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAA--RKR 185 Q IE ++L+++ A I + I+T G S+ + L A K+ Sbjct: 373 QFAKEKIELADQLIID----------NASTQIEESTTIVTYGSSKVLTELLLHNAISLKK 422 Query: 186 KFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMS-RVNKVIIGTKTILANGA 244 VIV + P +G +MA L AG+ ++ + + V+ V +G +IL+NG Sbjct: 423 NIKVIVVDSRPLFEGRKMAETLRNAGVNVMYALITSLDTIFNMDVDYVFLGAHSILSNGF 482 Query: 245 LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVL 295 L + GT LA++AK + P++VC K S + + +F++ P +++ Sbjct: 483 LYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLDSVTFNELADPNDLV 533 >2YRF-A nrPDB Length = 374 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 59/219 (26%), Positives = 88/219 (40%), Gaps = 25/219 (11%) Query: 130 QSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG---------FSRTVEAFLKE 180 ++N++ ++ VE E T I AL+ + IMTI + + F Sbjct: 142 KTNLVHEAIQIQVEDEETCRLIGQNALQLFKKGDRIMTICNAGSIATSRYGTALAPFYLA 201 Query: 181 AARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMS--RVNKVIIGTK 237 + H+ E P QG + A L + GI+ T++TD+ M +++ VI+G Sbjct: 202 KQKDLGLHIYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQISAVIVGAD 261 Query: 238 TILANGALRAVTGTHTLALAAKHHSTPLIVCAPM------FKLSPQFPNEEDSFHKFVAP 291 I NG GT+ LA+ A P V AP+ K P EE P Sbjct: 262 RIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEERD------P 315 Query: 292 EEVLPFTEGDIL-EKVSVHCPVFDYVPPELITLFISNIG 329 EEV + V V P FD P +LI+ I+ G Sbjct: 316 EEVRQISGVRTAPSNVPVFNPAFDITPHDLISGIITEKG 354 >4LDQ-A nrPDB Length = 369 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 85/201 (42%), Gaps = 6/201 (2%) Query: 156 LEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIET 214 L H ++ + T G+ + + R H E P+ QG + A L I Sbjct: 165 LTHCNTG-ALATAGYGTALGVIRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPA 223 Query: 215 TVMTDAAIFAVMSR--VNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMF 272 T++TD+ + A M+ V+ V++G ++ANG GT+ LA+ AKHH P V AP Sbjct: 224 TLITDSMVAAAMAHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSS 283 Query: 273 KLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEK-VSVHCPVFDYVPPELIT-LFISNIGG 330 + ++ + +E+ I + V P FD P +LIT I+ +G Sbjct: 284 SCDLRLETGKEIIIEERPGQELTDVNGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGV 343 Query: 331 NAPSYIYRLMSELYHPDDHVL 351 AP + ++ D L Sbjct: 344 FAPEELRTALTTTISSRDGTL 364 >5DBO-A nrPDB Length = 466 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 58/193 (30%), Positives = 91/193 (47%), Gaps = 23/193 (11%) Query: 151 IAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRK-FHVIVAECAPFCQGHEMAVNLSK 209 IA A + I+ + I+T G R VE L A ++ K F+V V + +G E+A L Sbjct: 272 IARNAAQSINDGDTIVTYGRHRLVEKTLLRARKEGKSFNVTVLDDPYVGEGKELAKVLRH 331 Query: 210 AGIETTVMTDAAIFAVMSRV---NKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLI 266 AGI V+ + + S+V + V +G + I ANG+L A +GT +A+AA + +I Sbjct: 332 AGI--PVLYSPNLGGLRSKVPAASNVFLGGEAIFANGSLHAPSGTADVAMAATNAGAKVI 389 Query: 267 VCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHC--PVFDYVPPELITLF 324 V E +F + + L + E D E+ + C +FD IT Sbjct: 390 VLC-----------ETINFDRERVSVDALTYNEIDP-ERNTGDCFRLLFDNTHERYITGV 437 Query: 325 ISNI---GGNAPS 334 I+ I GGN+P+ Sbjct: 438 ITEIEFGGGNSPA 450 >2A0U-A nrPDB Length = 383 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 45/159 (28%), Positives = 70/159 (44%), Gaps = 15/159 (9%) Query: 188 HVIVAECAPFCQGHEMAV-NLSKAGIETTVMTDAAIFAVM--SRVNKVIIGTKTILANGA 244 V E P+ QG + V + I T++ D A ++M +++ V++G I NG Sbjct: 213 RVYACETRPWNQGARLTVYECVQEDIPCTLICDGAASSLMLNRKIDAVVVGADRICQNGD 272 Query: 245 LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILE 304 GT+ LA++AK H L V AP L + + H + E T + + Sbjct: 273 TANKIGTYNLAVSAKFHGVKLYVAAPTTTLDVKTASGN---HVEIEEREPTEITTNLVTK 329 Query: 305 K--------VSVHCPVFDYVPPELIT-LFISNIGGNAPS 334 + +S+ PVFD P ELIT I+ G AP+ Sbjct: 330 QRVVADGPHLSIWNPVFDITPSELITGGIITEKGVQAPA 368 >3CQ0-A nrPDB Length = 339 Score = 31.6 bits (70), Expect = 0.53, Method: Compositional matrix adjust. Identities = 51/221 (23%), Positives = 90/221 (40%), Gaps = 38/221 (17%) Query: 32 EEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIRE 91 +++A +L L++ T H +++G+ + + E + T PS + + + + I Sbjct: 9 QKVATSSLEQLKKAGT-HVVADSGDFEAISKYEPQDSTT-NPSLILAASKLEKYARFIDA 66 Query: 92 --EYGRLHGRSDESDQQESLHKLLTSGG--------------LNEDFSF----------H 125 EYGR HG++D + ++ K+L G ++ SF H Sbjct: 67 AVEYGRKHGKTDHEKIENAMDKILVEFGTQILKVVPGRVSTEVDARLSFDKKATVKKALH 126 Query: 126 YAQLQSNIIEAINELLVELEGTMENI-AAQALEHIHSNEVIMTIGFSRTVEAFLKEAARK 184 +L + +L+++ T E I AA+ LE H MT+ FS T EA Sbjct: 127 IIKLYKDAGVPKERVLIKIASTWEGIQAARELEVKHGIHCNMTLLFSFTQAVACAEAN-- 184 Query: 185 RKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAV 225 V +PF G M + +G + T TD + +V Sbjct: 185 ------VTLISPFV-GRIMDFYKALSGKDYTAETDPGVLSV 218 >3E8J-A nrPDB Length = 306 Score = 31.6 bits (70), Expect = 0.60, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 2/65 (3%) Query: 254 LALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFH-KFVAPEEVLPFTEGDILEKVSVHCPV 312 L +A K P+ F L+P + EED ++ VA E PF D+ E+ C Sbjct: 117 LFVAEKEGKEPVWWFGGGFDLTPYYAVEEDCYYFHHVAQELCRPFG-ADVYERFKAWCDE 175 Query: 313 FDYVP 317 + ++P Sbjct: 176 YFFIP 180 >5NNB-A nrPDB Length = 257 Score = 30.8 bits (68), Expect = 0.91, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 9/66 (13%) Query: 226 MSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSF 285 MS +N+++ G LA+GA+R V THTL P+IV P F +F EE S Sbjct: 1 MSSLNQLVSG----LASGAVRIVDLTHTL-----DPDFPVIVLPPEFGQCARFRMEEISA 51 Query: 286 HKFVAP 291 + P Sbjct: 52 YDHRGP 57 >5KUF-A nrPDB Length = 877 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 6/49 (12%) Query: 171 SRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTD 219 ++ + LKE R ++FHVI +C+ HEMA + K + +MT+ Sbjct: 177 TKDAKPLLKEMKRGKEFHVIF-DCS-----HEMAAGILKQALAMGMMTE 219 >5KUH-A nrPDB Length = 757 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 6/49 (12%) Query: 171 SRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTD 219 ++ + LKE R ++FHVI +C+ HEMA + K + +MT+ Sbjct: 177 TKDAKPLLKEMKRGKEFHVIF-DCS-----HEMAAGILKQALAMGMMTE 219 >3FLU-A nrPDB Length = 297 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 17/94 (18%) Query: 106 QESLHKLLTSGGLNEDFSFHYAQLQSNI---IEAINELLVELEGTMENIAAQALEHIHSN 162 Q SL L+T +N+D S HY QL+ I IE + +V + T E+ EH Sbjct: 9 QGSLVALITP--MNQDGSIHYEQLRDLIDWHIENGTDGIVAVGTTGESATLSVEEHTAVI 66 Query: 163 E-----------VIMTIGFSRTVEAF-LKEAARK 184 E VI G + TVEA L +AA K Sbjct: 67 EAVVKHVAKRVPVIAGTGANNTVEAIALSQAAEK 100 >5W61-A nrPDB Length = 194 Score = 27.7 bits (60), Expect = 7.4, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 20/37 (54%) Query: 24 RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60 RGGGP SSE++ + LL+ I D GE EL Sbjct: 9 RGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPEL 45 >4JWP-A nrPDB Length = 185 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 17/24 (70%) Query: 169 GFSRTVEAFLKEAARKRKFHVIVA 192 G RT+ A L E AR+RK HV++A Sbjct: 118 GIGRTLLAELIEEARERKVHVLIA 141 >4BD6-A nrPDB Length = 174 Score = 27.7 bits (60), Expect = 8.5, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 20/37 (54%) Query: 24 RGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMEL 60 RGGGP SSE++ + LL+ I D GE EL Sbjct: 9 RGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPEL 45 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6O81-C nrPDB 483 e-137 6I3M-E nrPDB 375 e-104 6JLZ-C nrPDB 341 2e-94 3A9C-A nrPDB 273 7e-74 5YG5-A nrPDB 261 2e-70 6O85-G nrPDB 241 2e-64 6I3M-A nrPDB 240 6e-64 6O85-E nrPDB 236 1e-62 5B04-A nrPDB 231 4e-61 2YRF-A nrPDB 220 9e-58 4LDQ-A nrPDB 218 2e-57 5B04-G nrPDB 216 8e-57 1T9K-A nrPDB 215 2e-56 1VB5-A nrPDB 213 9e-56 6A34-A nrPDB 204 5e-53 1T5O-A nrPDB 198 3e-51 6I7T-C nrPDB 198 4e-51 2A0U-A nrPDB 171 3e-43 5DBO-A nrPDB 167 7e-42 Sequences not found previously or not previously below threshold: 2WHD-A nrPDB 33 0.22 4H59-A nrPDB 33 0.23 3D8X-A nrPDB 32 0.29 1UAA-A nrPDB 32 0.39 2W7T-A nrPDB 32 0.45 3T6C-A nrPDB 31 0.87 4IHC-A nrPDB 30 1.1 3TW9-A nrPDB 30 1.2 5W4C-A nrPDB 30 1.3 5VLB-A nrPDB 30 1.8 2VA8-A nrPDB 30 1.9 6BPY-A nrPDB 30 2.1 3NNN-A nrPDB 29 2.3 5HVM-A nrPDB 29 2.4 1KGS-A nrPDB 29 2.7 4RW5-A nrPDB 29 2.8 3RLH-A nrPDB 29 2.8 2VXO-A nrPDB 29 3.3 1QVS-A nrPDB 29 3.8 5JRH-A nrPDB 29 4.3 5UIC-A nrPDB 29 4.4 4CBQ-A nrPDB 29 4.5 1TYG-A nrPDB 29 4.6 4G0L-A nrPDB 29 4.8 1VDC-A nrPDB 28 6.7 2VE7-C nrPDB 28 6.7 CONVERGED! >6O81-C nrPDB Length = 368 Score = 483 bits (1242), Expect = e-137, Method: Composition-based stats. Identities = 350/350 (100%), Positives = 350/350 (100%) Query: 2 PGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELI 61 PGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELI Sbjct: 19 PGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELI 78 Query: 62 RREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNED 121 RREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNED Sbjct: 79 RREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNED 138 Query: 122 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA 181 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA Sbjct: 139 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA 198 Query: 182 ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA 241 ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA Sbjct: 199 ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILA 258 Query: 242 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD 301 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD Sbjct: 259 NGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD 318 Query: 302 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 351 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL Sbjct: 319 ILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELYHPDDHVL 368 >6I3M-E nrPDB Length = 381 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 118/367 (32%), Positives = 194/367 (52%), Gaps = 30/367 (8%) Query: 6 AKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREG 65 A S+++ I++FV LKR + S +A ETL LL + I+ RW++ +L+E IR G Sbjct: 13 AATSDVNVTIDTFVAKLKRRQ-VQGSYAIALETLQLLMRFISAARWNHVNDLIEQIRDLG 71 Query: 66 RRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSD------------------ESDQQE 107 + A P+ + GN++RR+L ++R+E + + +Q Sbjct: 72 NSLEKAHPTAFSCGNVIRRILAVLRDEVEEDTMSTTVTSTSVAEPLISSMFNLLQKPEQP 131 Query: 108 SLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMT 167 ++ +SG + Y Q+ I+ I +L+ E++ E I A++ IH +E+++T Sbjct: 132 HQNRKNSSGSSSMKTKTDYRQVA---IQGIKDLIDEIKNIDEGIQQIAIDLIHDHEILLT 188 Query: 168 -IGFSRTVEAFLKEAARK--RKFHVIVAECAPFC--QGHEMAVNLSKAGIETTVMTDAAI 222 S+TV FL A + R F V+V E P HE A L++ IET V+ D+A+ Sbjct: 189 PTPDSKTVLKFLITARERSNRTFTVLVTEGFPNNTKNAHEFAKKLAQHNIETLVVPDSAV 248 Query: 223 FAVMSRVNKVIIGTKTILANGALR-AVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNE 281 FA+MSRV KVIIGTK + NG + +G ++ A+ TP+ A ++KLSP +P + Sbjct: 249 FALMSRVGKVIIGTKAVFVNGGTISSNSGVSSVCECAREFRTPVFAVAGLYKLSPLYPFD 308 Query: 282 EDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMS 341 + F +F + +LP D +++ + DYVPPE I ++I+N+GG PS+IYR+ Sbjct: 309 VEKFVEFGGSQRILP--RMDPRKRLDTVNQITDYVPPENIDIYITNVGGFNPSFIYRIAW 366 Query: 342 ELYHPDD 348 + Y D Sbjct: 367 DNYKQID 373 >6JLZ-C nrPDB Length = 399 Score = 341 bits (875), Expect = 2e-94, Method: Composition-based stats. Identities = 141/382 (36%), Positives = 225/382 (58%), Gaps = 46/382 (12%) Query: 15 IESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPS 74 + S + LK + +A ET ++RQ+I+ RWS +L++ +R G + AQP+ Sbjct: 19 VSSLIADLKSRK-VQGPFAVAVETALVMRQVISQTRWSTVDQLIDTVRAVGSTLVKAQPT 77 Query: 75 ETTVGNMVRRVLKIIREEYGRLHGRSDESDQ---------QESLHKLLTSGGLNEDFSFH 125 E + GN++RR+L++IREEY L +DE+++ S + + S Sbjct: 78 EFSCGNIIRRILRLIREEYQELLKTADENEKLIVSSSNSSSPSQKRDIPSNEKLVQSHEP 137 Query: 126 YA----------------------------------QLQSNIIEAINELLVELEGTMENI 151 + +++ II I +++ EL+ +I Sbjct: 138 VSVQMYSSMLNLLGRPTLESPTHSKTVGDSRVTGGMDMRAVIISGIQDVIDELDKINTDI 197 Query: 152 AAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQ--GHEMAVNLSK 209 Q+++H+HSNE+I+T G S+TVEAFL+ AA+KRKF VIVAE P Q H MA L++ Sbjct: 198 EVQSMDHLHSNEIILTQGCSKTVEAFLRFAAKKRKFSVIVAEGFPNNQKGSHAMAKRLAQ 257 Query: 210 AGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCA 269 AGI+TTV++DA IFA+MSRVNKVI+GT IL NG L +G +A AA+HH+TP++VC+ Sbjct: 258 AGIDTTVISDATIFAIMSRVNKVILGTHAILGNGGLVTYSGAQLVAQAARHHATPVVVCS 317 Query: 270 PMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIG 329 ++KLSP +P + +S + +P++++ F EGD++ + + P +DY+PP+L+ LFI+N+G Sbjct: 318 GIYKLSPVYPYDLESIIQLSSPDKIMSFNEGDLISRAEILNPYYDYIPPDLVDLFITNLG 377 Query: 330 GNAPSYIYRLMSELYHPDDHVL 351 G PSY+YR+M++ Y D +L Sbjct: 378 GYPPSYLYRIMNDTYDASDTIL 399 >3A9C-A nrPDB Length = 338 Score = 273 bits (699), Expect = 7e-74, Method: Composition-based stats. Identities = 78/328 (23%), Positives = 131/328 (39%), Gaps = 29/328 (8%) Query: 19 VETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETTV 78 + + R + ++AR L+ + +N E + +++ + + +P+ ++ Sbjct: 26 IAEKIKNMEIRGAGKIARSAAYALQLQAEKSKATNVDEFWKEMKQAAKILFETRPTAVSL 85 Query: 79 GNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAIN 138 N +R V+ K+ S G QL+ II A Sbjct: 86 PNALRYVM---------------------HRGKIAYSSGA------DLEQLRFVIINAAK 118 Query: 139 ELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRK-FHVIVAECAPF 197 E + E +E I + I +VIMT S+ + +K A + K VIV E P Sbjct: 119 EFIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGKDIKVIVTETRPK 178 Query: 198 CQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALA 257 QG A L+ GI + D+A M +KV++G +I NGA+ GT +AL Sbjct: 179 WQGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALT 238 Query: 258 AKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILE-KVSVHCPVFDYV 316 AK H ++ A +K P+ + + P EV+P E + V P FD Sbjct: 239 AKEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNPAFDVT 298 Query: 317 PPELITLFISNIGGNAPSYIYRLMSELY 344 PPE + + I+ G P ++ E + Sbjct: 299 PPEYVDVIITERGIIPPYAAIDILREEF 326 >5YG5-A nrPDB Length = 324 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 72/292 (24%), Positives = 120/292 (41%), Gaps = 29/292 (9%) Query: 55 GELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLT 114 EL ++ + + +P+ ++ N +R V+ ++ Y Sbjct: 48 EELWNELKVASKILYNTRPTAVSLPNALRYVMHRVKAAY--------------------- 86 Query: 115 SGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTV 174 GG + + L+ I + E + E +E I + I ++IMT S+ Sbjct: 87 LGGADLET------LRFTAINSAKEFIYNSEKAIERIGEIGAKRIEDGDIIMTHCHSKAA 140 Query: 175 EAFLKEAARKRK-FHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVI 233 + +K+A + K VIV E P QG A L+ GI + D+A M +KV+ Sbjct: 141 ISVMKKAFEQGKNIKVIVTETRPKWQGKITAKELASYGIPVIYIVDSAARHYMKMTDKVV 200 Query: 234 IGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEE 293 +G +I ANGA+ GT +AL AK H +++ A +K P + + P E Sbjct: 201 MGADSITANGAVINKIGTSLIALTAKEHRVWVMIAAETYKFHPATMLGQLVEIEMRDPTE 260 Query: 294 VLPFTEGDILE-KVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELY 344 V+P E + V P FD PPE I + I+ G P ++ E + Sbjct: 261 VIPEEELRTWPKNIEVWNPAFDVTPPEYIDVIITERGIIPPYAAIDILKEEF 312 >6O85-G nrPDB Length = 305 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 68/224 (30%), Positives = 106/224 (47%), Gaps = 8/224 (3%) Query: 125 HYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEA-AR 183 Y++ + +IE L + + IA I I+T +SR V L+ A A Sbjct: 85 DYSKCKKIMIERGELFLRRISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAA 144 Query: 184 KRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG 243 K++F V V E P G +MA L + TV+ DAA+ +M + + VI+G + ++ NG Sbjct: 145 KKRFSVYVTESQPDLSGKKMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENG 204 Query: 244 ALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPN-EEDSFHKFVAPEEVLPF--TEG 300 + GT+ +A+ AK + P V A FK FP ++D KF + L T Sbjct: 205 GIINKIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQ 264 Query: 301 DILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRLMSELY 344 D+ E+ P DY P LITL +++G PS + + +LY Sbjct: 265 DLKEE----HPWVDYTAPSLITLLFTDLGVLTPSAVSDELIKLY 304 >6I3M-A nrPDB Length = 305 Score = 240 bits (613), Expect = 6e-64, Method: Composition-based stats. Identities = 70/316 (22%), Positives = 131/316 (41%), Gaps = 42/316 (13%) Query: 35 ARETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETT----VGNMVRRVLKIIR 90 A E L L +I T A E++ I+ + + P+ + +R VL+ Sbjct: 26 AIEALVTLLRIKTP---ETAAEMINTIKSSTEELIKSIPNSVSLRAGCDIFMRFVLR--- 79 Query: 91 EEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMEN 150 N + + ++IE + + + Sbjct: 80 ----------------------------NLHLYGDWENCKQHLIENGQLFVSRAKKSRNK 111 Query: 151 IAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKR-KFHVIVAECAPFCQGHEMAVNLSK 209 IA ++ I +++I+ G+SR V + L AA K +F +V E P QG+++ L + Sbjct: 112 IAEIGVDFIADDDIILVHGYSRAVFSLLNHAANKFIRFRCVVTESRPSKQGNQLYTLLEQ 171 Query: 210 AGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCA 269 GI T++ D+A+ AV+ +V+KV +G + + +G + + GT+++ + A + P V Sbjct: 172 KGIPVTLIVDSAVGAVIDKVDKVFVGAEGVAESGGIINLVGTYSVGVLAHNARKPFYVVT 231 Query: 270 PMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIG 329 K FP D P L FT + ++ P DY E IT I+++G Sbjct: 232 ESHKFVRMFPLSSDDLPMAGPP---LDFTRRTDDLEDALRGPTIDYTAQEYITALITDLG 288 Query: 330 GNAPSYIYRLMSELYH 345 PS + + ++++ Sbjct: 289 VLTPSAVSEELIKMWY 304 >6O85-E nrPDB Length = 523 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 76/324 (23%), Positives = 141/324 (43%), Gaps = 41/324 (12%) Query: 26 GGPRSSEEMARETLGLLRQIITDH----RWSNAGELMELIRREGRRMTAAQPSETTVGNM 81 G S L L+Q+I D+ + +L+ ++ +T +P ++ N Sbjct: 217 GLVSGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNA 276 Query: 82 VRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELL 141 ++ L+K +TS G ++ ++L++ I + E + Sbjct: 277 IKF------------------------LNKEITSVGSSKREEEAKSELRAAIDRYVQEKI 312 Query: 142 VELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAA-RKRKFHVIVAECAPFCQG 200 V + I+ A + I + +VI+ G S V L+EA R+F V+V + P+ +G Sbjct: 313 V---LAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEG 369 Query: 201 HEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKH 260 +L AG+ + + A V+ V+KV++G +LANG++ + GT LAL A+ Sbjct: 370 RHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARA 429 Query: 261 HSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGD--ILEKVSVH------CPV 312 H+ P++VC +K + + ++ P++ L G+ L H V Sbjct: 430 HNVPVLVCCETYKFCERVQTDAFVSNELDDPDD-LQCKRGEHVALANWQNHASLRLLNLV 488 Query: 313 FDYVPPELITLFISNIGGNAPSYI 336 +D PPEL+ L I+ +G S + Sbjct: 489 YDVTPPELVDLVITELGMIPCSSV 512 >5B04-A nrPDB Length = 341 Score = 231 bits (589), Expect = 4e-61, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 101/242 (41%), Gaps = 22/242 (9%) Query: 125 HYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARK 184 + Q + +++E + + IA I VI+T GFSR V A L AA++ Sbjct: 99 DFEQCKRHLVENGKLFIQRARACRQRIAHLGYPLIRDGSVILTHGFSRGVAAVLLAAAKR 158 Query: 185 R-KFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANG 243 +F V V E P G M L A I T ++ D+A+ M+RV+ V++G + ++ NG Sbjct: 159 HVRFKVFVTESRPSGSGCLMTRTLKNACIPTCMVLDSAVSFTMNRVDLVLVGAEGVVENG 218 Query: 244 ALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVA--------PEEVL 295 L GT LA+ AKH P A K FP + PE V Sbjct: 219 GLINQIGTFQLAVFAKHAHKPFYAVAESHKFVRMFPLSQYDIPFSRPILEFDDPSPETVH 278 Query: 296 PFTEGDILEKVSVH------------CPVFDYVPPELITLFISNIGGN-APSYIYRLMSE 342 P E ++H P D PPE ++ I+++G + S + + + Sbjct: 279 PEPEPIPTPSDAIHNELIMNEEQIRNNPTLDVTPPEFVSGLITDLGIIDSKSGVSEELIK 338 Query: 343 LY 344 LY Sbjct: 339 LY 340 >2YRF-A nrPDB Length = 374 Score = 220 bits (559), Expect = 9e-58, Method: Composition-based stats. Identities = 73/341 (21%), Positives = 121/341 (35%), Gaps = 50/341 (14%) Query: 10 ELSERIESF--VETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRREGRR 67 EL+ + + F + TLK G P A + I TD N E + + Sbjct: 55 ELTTKEDVFDAIVTLKVRGAPAIGITAAFGLALAAKDIETD----NVTEFRRRLEDIKQY 110 Query: 68 MTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYA 127 + +++P+ + + R+ + Sbjct: 111 LNSSRPTAINLSWALERLSHSVENAIS-------------------------------VN 139 Query: 128 QLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG---------FSRTVEAFL 178 + ++N++ ++ VE E T I AL+ + IMTI + + F Sbjct: 140 EAKTNLVHEAIQIQVEDEETCRLIGQNALQLFKKGDRIMTICNAGSIATSRYGTALAPFY 199 Query: 179 KEAARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--VNKVIIG 235 + H+ E P QG + A L + GI+ T++TD+ M ++ VI+G Sbjct: 200 LAKQKDLGLHIYACETRPVLQGSRLTAWELMQGGIDVTLITDSMAAHTMKEKQISAVIVG 259 Query: 236 TKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVL 295 I NG GT+ LA+ A P V AP+ + D + PEEV Sbjct: 260 ADRIAKNGDTANKIGTYGLAILANAFDIPFFVAAPLSTFDTKVKCGADIPIEERDPEEVR 319 Query: 296 PFTEGDILE-KVSVHCPVFDYVPPELITLFISNIGGNAPSY 335 + V V P FD P +LI+ I+ G +Y Sbjct: 320 QISGVRTAPSNVPVFNPAFDITPHDLISGIITEKGIMTGNY 360 >4LDQ-A nrPDB Length = 369 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 63/296 (21%), Positives = 114/296 (38%), Gaps = 15/296 (5%) Query: 61 IRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNE 120 +R + + A+P+ + R + + E R E +E++ + + + Sbjct: 79 VRDKLSFLVTARPTAVNMARAARDLADVAAREAER------EGATEEAVRERVICCTEDM 132 Query: 121 DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE 180 +S LL + + + L H ++ + T G+ + Sbjct: 133 -LEKDLRDNRSIGDLGARHLLERVAPSGGKVTV--LTHCNTG-ALATAGYGTALGVIRSL 188 Query: 181 AARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--VNKVIIGTK 237 + R H E P+ QG + A L I T++TD+ + A M+ V+ V++G Sbjct: 189 HSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVVVGAD 248 Query: 238 TILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPF 297 ++ANG GT+ LA+ AKHH P V AP + ++ + +E+ Sbjct: 249 RVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQELTDV 308 Query: 298 TEGDI-LEKVSVHCPVFDYVPPELIT-LFISNIGGNAPSYIYRLMSELYHPDDHVL 351 I + V P FD P +LIT I+ +G AP + ++ D L Sbjct: 309 NGVRIAAPGIGVWNPAFDVTPHDLITGGIITELGVFAPEELRTALTTTISSRDGTL 364 >5B04-G nrPDB Length = 467 Score = 216 bits (551), Expect = 8e-57, Method: Composition-based stats. Identities = 61/288 (21%), Positives = 118/288 (40%), Gaps = 40/288 (13%) Query: 68 MTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYA 127 + + +P ++GN +R ++ E L + + +E L + + S Sbjct: 201 LVSTRPLSISMGNAIR----FLKLEISVLDIDLTDDEGKELLLEKIDSY----------- 245 Query: 128 QLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAAR-KRK 186 + + + I A E I +VI+T S TV L A +K Sbjct: 246 ------------IRDRIIIAGQVIVQAATEKIQDGDVILTYLHSSTVNDVLIHAKNVGKK 293 Query: 187 FHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALR 246 F V+V + P +G L++ GIE T + +A+ +M V K+ +G +L+NGAL Sbjct: 294 FRVVVVDSRPEFEGRVCLKLLTEHGIECTYVMISALSYIMQEVTKIFLGGHAMLSNGALY 353 Query: 247 AVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKV 306 + GT ++L + P+I C +K + + + +++ ++++ D EK Sbjct: 354 SRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGDQLVNMGVDDFEEKP 413 Query: 307 SVHCPV------------FDYVPPELITLFISNIGGNAPSYIYRLMSE 342 V +D PP LIT+ + +G + + +++E Sbjct: 414 GVLANWKSVKNLKLLSLKYDVTPPRLITVCVCEMGLLPSTSVPAIINE 461 >1T9K-A nrPDB Length = 347 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 55/227 (24%), Positives = 87/227 (38%), Gaps = 13/227 (5%) Query: 122 FSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG---------FSR 172 + L + ++ E + I + I I+T + Sbjct: 109 ENADRENLFEILENEALKMAYEDIEVNKAIGKNGAQLIKDGSTILTHCNAGALATVDYGT 168 Query: 173 TVEAFLKEAARKRKFHVIVAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR--V 229 + ++ V E P+ QG + A L K GIE V+TD +M R + Sbjct: 169 ALGVIRAAVESGKRIRVFADETRPYLQGARLTAWELMKDGIEVYVITDNMAGWLMKRGLI 228 Query: 230 NKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFV 289 + V++G I NG GT++LA+ AK ++ P V AP+ + P + E+ + Sbjct: 229 DAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEER 288 Query: 290 APEEVLPFTEGDILEK-VSVHCPVFDYVPPELITLFISNIGGNAPSY 335 PEEV I + V V P FD LIT I+ G P + Sbjct: 289 RPEEVTHCGGNRIAPEGVKVLNPAFDVTENTLITAIITEKGVIRPPF 335 >1VB5-A nrPDB Length = 276 Score = 213 bits (542), Expect = 9e-56, Method: Composition-based stats. Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 12/206 (5%) Query: 130 QSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAAR-KRKFH 188 + + E L +E +A+ + I +VI+T FS TV ++ A K++F Sbjct: 78 RDILKSRALEFLRRMEEAKRELASIGAQLIDDGDVIITHSFSSTVLEIIRTAKERKKRFK 137 Query: 189 VIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAV 248 VI+ E +P +G +A L +GIE V+TDA + + I+G I +G + Sbjct: 138 VILTESSPDYEGLHLARELEFSGIEFEVITDAQMGLFCREASIAIVGADMITKDGYVVNK 197 Query: 249 TGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSV 308 GT+ LALA ++ P V A +K P + +V+ I V + Sbjct: 198 AGTYLLALACHENAIPFYVAAETYKFHPTLKSG-----------DVMLMERDLIRGNVRI 246 Query: 309 HCPVFDYVPPELITLFISNIGGNAPS 334 +FD P + + I+ +G P Sbjct: 247 RNVLFDVTPWKYVRGIITELGIVIPP 272 >6A34-A nrPDB Length = 364 Score = 204 bits (519), Expect = 5e-53, Method: Composition-based stats. Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 13/232 (5%) Query: 120 EDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG--------FS 171 E +++ I++ ++ E + E + I+T Sbjct: 119 EHSEDPLDEIKRLIVQEAYKIADEDVEANLRMGHYGAEVLPEGN-ILTHCNAGSLATVHL 177 Query: 172 RTVEAFLKEAARKRKFHVI-VAECAPFCQGHEM-AVNLSKAGIETTVMTDAAIFAVMSR- 228 TV + ++ + ++ + E P QG + A S G+ ++ D A VM + Sbjct: 178 GTVGSVVRVMHKDGSLKLLWLDETRPVLQGARLSAWEYSYDGLNVKLIADNAAAFVMQQG 237 Query: 229 -VNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHK 287 V+ +I+G I+ANG GT+ LA+ A+ H P AP+ + + + +D + Sbjct: 238 FVDAIIVGADRIVANGDFANKIGTYMLAVLAREHGIPFFAVAPLSSIDMELKSGKDIPIE 297 Query: 288 FVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPSYIYRL 339 +PEEVL I V V+ P FD P + +T I++ G P + L Sbjct: 298 ERSPEEVLTCGGCRIAPDVPVYNPAFDVTPHKYLTGIITDRGVVWPPFKRNL 349 >1T5O-A nrPDB Length = 351 Score = 198 bits (503), Expect = 3e-51, Method: Composition-based stats. Identities = 53/225 (23%), Positives = 95/225 (42%), Gaps = 15/225 (6%) Query: 124 FHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG---------FSRTV 174 +++ + +L E + E + +V++T + + Sbjct: 109 ESVEEVKELALREAEKLAEEDVERNRKMGEYGAELLEDGDVVLTYCNAGRLATVDWGTAL 168 Query: 175 EAFLKEAARKRKFHVIVAECAPFCQGHEMA-VNLSKAGIETTVMTDAAIFAVMSR--VNK 231 + ++ VI E P QG + L + GI+ T++TD+ + VM + V+K Sbjct: 169 GVVRSAVEQGKEIRVIACETRPLNQGSRLTCWELMEDGIDVTLITDSMVGIVMQKGMVDK 228 Query: 232 VIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAP 291 VI+G I+ + A+ GT+T+++ AKHH+ P V AP + +D + Sbjct: 229 VIVGADRIVRD-AVFNKIGTYTVSVVAKHHNIPFYVAAPKATFDWE-RTAKDVVIEERPR 286 Query: 292 EEVLPFTEGDILE-KVSVHCPVFDYVPPELITLFISNIGGNAPSY 335 EE++ + I V V+ P FD P E +T I+ G P Y Sbjct: 287 EELIFCGKRQIAPLNVKVYNPAFDPTPLENVTALITEYGVIYPPY 331 >6I7T-C nrPDB Length = 651 Score = 198 bits (502), Expect = 4e-51, Method: Composition-based stats. Identities = 56/241 (23%), Positives = 105/241 (43%), Gaps = 30/241 (12%) Query: 68 MTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYA 127 + A+P T+GN +R +++E + D S ++ K D Sbjct: 330 LKKARPLSVTMGNAIRW----LKQEISLI----DPSTPDKAAKK---------DLCEKIG 372 Query: 128 QLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAA--RKR 185 Q IE ++L+++ A I + I+T G S+ + L A K+ Sbjct: 373 QFAKEKIELADQLIID----------NASTQIEESTTIVTYGSSKVLTELLLHNAISLKK 422 Query: 186 KFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSR-VNKVIIGTKTILANGA 244 VIV + P +G +MA L AG+ ++ + + V+ V +G +IL+NG Sbjct: 423 NIKVIVVDSRPLFEGRKMAETLRNAGVNVMYALITSLDTIFNMDVDYVFLGAHSILSNGF 482 Query: 245 LRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILE 304 L + GT LA++AK + P++VC K S + + +F++ P +++ + +E Sbjct: 483 LYSRAGTAMLAMSAKRRNIPVLVCCESLKFSQRVQLDSVTFNELADPNDLVNIDYENPVE 542 Query: 305 K 305 + Sbjct: 543 R 543 >2A0U-A nrPDB Length = 383 Score = 171 bits (434), Expect = 3e-43, Method: Composition-based stats. Identities = 56/251 (22%), Positives = 94/251 (37%), Gaps = 26/251 (10%) Query: 111 KLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHI--------HSN 162 + L + D + A++ +E + E I HI Sbjct: 119 RDLKAQVDKLDPTKAAAEVAQAFVELAEAVYTNDVAFNEGIMRHGAAHILAAAKAEGRDK 178 Query: 163 EVIMTIG---------FSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAV-NLSKAGI 212 I+TI + + + + V E P+ QG + V + I Sbjct: 179 VSILTICNTGALATSRYGTALGVVRQLFYDGKLERVYACETRPWNQGARLTVYECVQEDI 238 Query: 213 ETTVMTDAAIFAVM--SRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAP 270 T++ D A ++M +++ V++G I NG GT+ LA++AK H L V AP Sbjct: 239 PCTLICDGAASSLMLNRKIDAVVVGADRICQNGDTANKIGTYNLAVSAKFHGVKLYVAAP 298 Query: 271 MFKLSPQFPNEEDSFHKFVAPEEVLP--FTEGDIL---EKVSVHCPVFDYVPPELIT-LF 324 L + + + P E+ T+ ++ +S+ PVFD P ELIT Sbjct: 299 TTTLDVKTASGNHVEIEEREPTEITTNLVTKQRVVADGPHLSIWNPVFDITPSELITGGI 358 Query: 325 ISNIGGNAPSY 335 I+ G AP+ Sbjct: 359 ITEKGVQAPAA 369 >5DBO-A nrPDB Length = 466 Score = 167 bits (422), Expect = 7e-42, Method: Composition-based stats. Identities = 65/276 (23%), Positives = 111/276 (40%), Gaps = 50/276 (18%) Query: 68 MTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYA 127 +T +P +GN +R +++ + + + E + +E L Sbjct: 216 LTECRPMCFAMGNAIR----LLKAKVNKFDINTPEDEAKEGL------------------ 253 Query: 128 QLQSNIIEAINELL-VELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRK 186 +E I+ L+ + IA A + I+ + I+T G R VE L A ++ K Sbjct: 254 ------LEWIDFLINERITLAEYVIARNAAQSINDGDTIVTYGRHRLVEKTLLRARKEGK 307 Query: 187 -FHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRV---NKVIIGTKTILAN 242 F+V V + +G E+A L AGI + + S+V + V +G + I AN Sbjct: 308 SFNVTVLDDPYVGEGKELAKVLRHAGIPVLY--SPNLGGLRSKVPAASNVFLGGEAIFAN 365 Query: 243 GALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDI 302 G+L A +GT +A+AA + +IV +F + + L + E D Sbjct: 366 GSLHAPSGTADVAMAATNAGAKVIVLCET-----------INFDRERVSVDALTYNEIDP 414 Query: 303 LEKVS-VHCPVFDYVPPELITLFISNI---GGNAPS 334 +FD IT I+ I GGN+P+ Sbjct: 415 ERNTGDCFRLLFDNTHERYITGVITEIEFGGGNSPA 450 >2WHD-A nrPDB Length = 351 Score = 32.8 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 18/58 (31%), Gaps = 3/58 (5%) Query: 195 APFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTH 252 + G + GI + D A ++ VI G + + G G+ Sbjct: 148 RLYFSGSDTYW---NRGISACAVCDGAAPIFRNKPIAVIGGGDSAMEEGNFLTKYGSQ 202 >4H59-A nrPDB Length = 308 Score = 32.8 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Query: 135 EAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFSRTVEAF 177 E++ E E E I+A+ I+ +VI+T G +T+EA Sbjct: 211 ESLKEFESEDSFAKE-ISAEEANKINDADVIITYGDDKTLEAL 252 >3D8X-A nrPDB Length = 326 Score = 32.4 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 20/62 (32%), Gaps = 3/62 (4%) Query: 200 GHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAK 259 G E + GI + D A+ ++ VI G + G+ L K Sbjct: 137 GEETYW---QKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRK 193 Query: 260 HH 261 H Sbjct: 194 DH 195 >1UAA-A nrPDB Length = 673 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 58/171 (33%), Gaps = 27/171 (15%) Query: 5 AAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQIITDHRWSNAGELMELIRRE 64 A GS + I + + L RG G ++ A R E+ R Sbjct: 22 AGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTN------KAAR--------EMKERV 67 Query: 65 GRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSD----ESDQQESLHKLLTSGGLNE 120 G+ + + + L II+ EY L +++ + Q +L K LT G + + Sbjct: 68 GQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIED 127 Query: 121 DFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIGFS 171 D +++ + + + ++ + A I + I + Sbjct: 128 D---------KVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYG 169 >2W7T-A nrPDB Length = 273 Score = 31.6 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 8/45 (17%), Positives = 13/45 (28%), Gaps = 2/45 (4%) Query: 227 SRVNKVIIGTKTILANGALRAVT--GTHTLALAAKHHSTPLIVCA 269 K ++G I G G A A+ ++ P Sbjct: 59 DEARKALLGCDGIFVPGGFGNRGVDGKCAAAQVARMNNIPYFGVC 103 >3T6C-A nrPDB Length = 440 Score = 30.9 bits (68), Expect = 0.87, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 40/111 (36%), Gaps = 16/111 (14%) Query: 245 LRAVTGTHTLALA--AKHHSTPLIV-----CAPMFKL----SPQFPNEEDSFHKFVAPEE 293 LR G ++ L A TP+ ++L P P + + Sbjct: 233 LRNKLG-FSVELLHDAHERITPINAIHMAKALEPYQLFFLEDPVAPENTEWLKMLRQ-QS 290 Query: 294 VLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPS---YIYRLMS 341 P G++ V+ P+ D + I IS+IGG P+ IY ++ Sbjct: 291 STPIAMGELFVNVNEWKPLIDNKLIDYIRCHISSIGGITPAKKIAIYSELN 341 >4IHC-A nrPDB Length = 440 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 30/70 (42%), Gaps = 4/70 (5%) Query: 275 SPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPS 334 P P E + + + + P + G++ ++ P+ D + I +S IGG P+ Sbjct: 273 DPVAP-ENIDWLRMLRQQSSTPISMGELFVNINEWKPLIDNKLIDYIRCHVSTIGGITPA 331 Query: 335 ---YIYRLMS 341 +Y ++ Sbjct: 332 KKLAVYSELN 341 >3TW9-A nrPDB Length = 442 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 4/70 (5%) Query: 275 SPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPS 334 P P E + K + + P + G++ V+ P+ D + I +S IGG P+ Sbjct: 275 DPVAP-ENIDWLKMLRQQSSTPISMGELFVNVNEWKPLIDNRLIDYIRCHVSTIGGITPA 333 Query: 335 ---YIYRLMS 341 +Y ++ Sbjct: 334 RKLAVYSELN 343 >5W4C-A nrPDB Length = 371 Score = 30.5 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 21/65 (32%), Gaps = 3/65 (4%) Query: 195 APFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTL 254 F G E ++GI + D A+ + VI G + G+H Sbjct: 153 RLFLPGEETYW---QSGISACAVCDGAVPIFRQKPLAVIGGGDSAAEEATYLTKYGSHVY 209 Query: 255 ALAAK 259 L + Sbjct: 210 VLVRR 214 >5VLB-A nrPDB Length = 446 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 38/128 (29%), Gaps = 22/128 (17%) Query: 188 HVIVAECAPFCQGHEMAVNL---SKAGIETTV-----MTDAAIFA---VMSRVNKVI--- 233 IV P G L KAG+ + +A+ +V K+ Sbjct: 159 KTIVLANPPTRDGTTCKEVLYCAKKAGVTHLLKAGGAQAISAMAWGTETCPKVEKIFGPG 218 Query: 234 ----IGTKTILANG----ALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSF 285 K IL N ++ G + + A H+ P V A + + P+ + Sbjct: 219 NQYVTAAKMILQNSEAMVSIDMPAGPSEVLVIADKHAIPSHVAADLLSQAEHGPDSQVVL 278 Query: 286 HKFVAPEE 293 + Sbjct: 279 VIAGDGVD 286 >2VA8-A nrPDB Length = 715 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 32/83 (38%) Query: 110 HKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTIG 169 K+ S L ++ L N + I + L ++E + I G Sbjct: 262 RKMAESTALKIANYMNFVSLDENALSEILKQLDDIEEGGSDEKELLKSLISKGVAYHHAG 321 Query: 170 FSRTVEAFLKEAARKRKFHVIVA 192 S+ + ++E R+RK VIVA Sbjct: 322 LSKALRDLIEEGFRQRKIKVIVA 344 >6BPY-A nrPDB Length = 374 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 20/65 (30%), Gaps = 3/65 (4%) Query: 195 APFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTL 254 G E + GI + D A+ ++ VI G + A G+ Sbjct: 129 RLNLPGEETYW---QNGISACAVCDGAVPIFRNKPLYVIGGGDSAAEEAMFLAKYGSSVT 185 Query: 255 ALAAK 259 L + Sbjct: 186 VLVRR 190 >3NNN-A nrPDB Length = 122 Score = 29.3 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 187 FHVIVAECA-PFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTK 237 F V++ + P G E+ ++ ++G+ T V+ A+ V RV + +G Sbjct: 47 FDVVILDIMLPVHDGWEILKSMRESGVNTPVLMLTALSDVEYRVKGLNMGAD 98 >5HVM-A nrPDB Length = 515 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 12/92 (13%), Positives = 28/92 (30%), Gaps = 6/92 (6%) Query: 89 IREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTM 148 +++EYG + D+ + S FHY + E+ E + Sbjct: 77 LKDEYGAIPVFIDDELADRHYNGFSNSILWPL---FHYHPGEITFDESAWE---AYKEAN 130 Query: 149 ENIAAQALEHIHSNEVIMTIGFSRTVEAFLKE 180 A + + ++I + + + Sbjct: 131 RLFAKAVAKEVQDGDLIWVHDYHLMLLPEMLR 162 >1KGS-A nrPDB Length = 225 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 187 FHVIVAECA-PFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTK 237 F V++ + P G E+ ++ ++G+ T V+ A+ V RV + +G Sbjct: 47 FDVVILDIMLPVHDGWEILKSMRESGVNTPVLMLTALSDVEYRVKGLNMGAD 98 >4RW5-A nrPDB Length = 302 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 163 EVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPF 197 + IMT + + L EAA K+KF V + P+ Sbjct: 264 DGIMTN-YPDVITDVLNEAAYKKKFRVATYDDNPW 297 >3RLH-A nrPDB Length = 329 Score = 29.3 bits (64), Expect = 2.8, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 18/35 (51%), Gaps = 1/35 (2%) Query: 163 EVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPF 197 + IMT + + L EAA K+KF V + P+ Sbjct: 291 DGIMTN-YPDVITDVLNEAAYKKKFRVATYDDNPW 324 >2VXO-A nrPDB Length = 697 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 19/63 (30%), Gaps = 2/63 (3%) Query: 266 IVCAPMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFI 325 VC K P + E F + P + V P D P L T + Sbjct: 532 YVCGISSKDEPDW--ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVL 589 Query: 326 SNI 328 S + Sbjct: 590 STL 592 >1QVS-A nrPDB Length = 309 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 58/179 (32%), Gaps = 10/179 (5%) Query: 85 VLKIIREEYGRLHGRSDESDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVEL 144 V K +E G + +Q + D + + L Sbjct: 16 VAKAFEQETGIKVTLNSGKSEQLAGQLKEEGDKTPADVFYTEQTATFADLSEAGLLAPIS 75 Query: 145 EGTMENIAAQALEHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMA 204 E T++ A + + + I G SR V + + K ++ P +G Sbjct: 76 EQTIQQTAQKGVPLAPKKDWIALSGRSRVVVYDHTKLSEKDMEKSVLDYATPKWKGKIGY 135 Query: 205 VNLSKAGIETTVMTDAAIFAVMSRVNKVIIG-TKTILANGALRAVTGTHTLALAAKHHS 262 V+ S A +E V +KV + K + NG L A +++AL A + Sbjct: 136 VSTSGAFLEQVVALSKMKG------DKVALNWLKGLKENGKLYAK---NSVALQAVENG 185 >5JRH-A nrPDB Length = 660 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 17/47 (36%), Gaps = 1/47 (2%) Query: 193 ECAPFC-QGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTKT 238 E P M + K + AI A+M+ +K I GT Sbjct: 331 EGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDR 377 >5UIC-A nrPDB Length = 144 Score = 28.6 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 21/49 (42%) Query: 189 VIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMSRVNKVIIGTK 237 V++ P G E+ N+ GI+ ++ A + R+ + +G Sbjct: 66 VVLDIGMPIKTGLEVLRNIRNRGIKVPIILLTARDGLEDRIKGLDLGAD 114 >4CBQ-A nrPDB Length = 314 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 38/112 (33%), Gaps = 10/112 (8%) Query: 209 KAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVC 268 + G+ + D A+ ++V V+ G + G+ + L H Sbjct: 134 QNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIIL---HRRDAFRAS 190 Query: 269 APMFKLSPQFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPV---FDYVP 317 M + P E ++ + E +GD+L +H V + VP Sbjct: 191 KTMQERVLNHPKIEVIWNSELVELE----GDGDLLNGAKIHNLVSGEYKVVP 238 >1TYG-A nrPDB Length = 253 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 16/93 (17%), Positives = 34/93 (36%), Gaps = 7/93 (7%) Query: 157 EHIHSNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGI---- 212 + + +++ V L + H I+ +P G + L+ + I Sbjct: 119 QLLEEGFIVLPYTSDDVV---LARKLEELGVHAIMPGASPIGSGQGILNPLNLSFIIEQA 175 Query: 213 ETTVMTDAAIFAVMSRVNKVIIGTKTILANGAL 245 + V+ DA I + + +G +L N A+ Sbjct: 176 KVPVIVDAGIGSPKDAAYAMELGADGVLLNTAV 208 >4G0L-A nrPDB Length = 328 Score = 28.6 bits (62), Expect = 4.8, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%) Query: 37 ETLGLLRQIITDHRWSNAGELMELIRREGRRMTAAQPSETT 77 E+L L QI+ HR+ +L E R + P T Sbjct: 215 ESLARLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVT 255 >1VDC-A nrPDB Length = 333 Score = 27.8 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 14/43 (32%) Query: 209 KAGIETTVMTDAAIFAVMSRVNKVIIGTKTILANGALRAVTGT 251 GI + D A ++ VI G + + G+ Sbjct: 141 NRGISACAVCDGAAPIFRNKPLAVIGGGDSAMEEANFLTKYGS 183 >2VE7-C nrPDB Length = 250 Score = 27.8 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 16/29 (55%) Query: 27 GPRSSEEMARETLGLLRQIITDHRWSNAG 55 GP ++ + ++ L R+ I+D+ WS Sbjct: 219 GPSVAQPIHLDSTQLSRKFISDYLWSLVD 247 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.127 0.307 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,037,132 Number of Sequences: 36641 Number of extensions: 375244 Number of successful extensions: 1424 Number of sequences better than 10.0: 46 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1284 Number of HSP's gapped (non-prelim): 89 length of query: 351 length of database: 10,336,785 effective HSP length: 98 effective length of query: 253 effective length of database: 6,745,967 effective search space: 1706729651 effective search space used: 1706729651 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.4 bits)