BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P49748 (655 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3B96-A nrPDB 1204 0.0 2Z1Q-A nrPDB 298 4e-81 3OWA-A nrPDB 264 1e-70 5LNX-A nrPDB 252 4e-67 5OL2-C nrPDB 238 7e-63 1BUC-A nrPDB 235 6e-62 4L1F-A nrPDB 233 2e-61 1UKW-A nrPDB 226 2e-59 2CX9-A nrPDB 224 7e-59 4N5F-A nrPDB 223 2e-58 3PFD-A nrPDB 220 1e-57 3NF4-A nrPDB 219 2e-57 2DVL-A nrPDB 215 6e-56 1JQI-A nrPDB 214 1e-55 2VIG-A nrPDB 212 5e-55 4KTO-A nrPDB 211 7e-55 1IVH-A nrPDB 209 3e-54 4U83-A nrPDB 207 8e-54 2JIF-A nrPDB 206 3e-53 4M9A-A nrPDB 205 5e-53 6FAH-C nrPDB 203 2e-52 4O5M-A nrPDB 202 4e-52 4IRN-A nrPDB 195 6e-50 1RX0-A nrPDB 190 2e-48 6ES9-A nrPDB 189 2e-48 5IDU-A nrPDB 185 7e-47 5JSC-A nrPDB 184 1e-46 2A1T-A nrPDB 179 3e-45 2PG0-A nrPDB 179 4e-45 4IV6-A nrPDB 178 7e-45 3MPI-A nrPDB 176 3e-44 3MDE-A nrPDB 172 4e-43 3GNC-A nrPDB 170 2e-42 1SIR-A nrPDB 150 2e-36 6CY8-B nrPDB 149 3e-36 4W9U-A nrPDB 148 7e-36 3SF6-A nrPDB 146 3e-35 5ZW7-A nrPDB 144 2e-34 2EBA-A nrPDB 140 1e-33 3R7K-A nrPDB 137 2e-32 3SWO-A nrPDB 134 2e-31 2IX5-A nrPDB 124 1e-28 3P4T-A nrPDB 122 5e-28 5AHS-A nrPDB 113 3e-25 4X28-A nrPDB 99 7e-21 1R2J-A nrPDB 97 2e-20 4RM7-A nrPDB 97 3e-20 4HR3-A nrPDB 96 7e-20 2WBI-A nrPDB 87 2e-17 5EZ3-A nrPDB 86 8e-17 4Y9J-A nrPDB 80 3e-15 5YS9-A nrPDB 70 3e-12 4XVX-A nrPDB 65 9e-11 4ZYJ-A nrPDB 63 3e-10 5Y9D-A nrPDB 61 1e-09 2C12-A nrPDB 60 2e-09 3U33-A nrPDB 60 3e-09 3M9V-A nrPDB 57 3e-08 2FON-A nrPDB 56 4e-08 3MXL-A nrPDB 56 6e-08 5XDD-A nrPDB 55 1e-07 4JEK-A nrPDB 54 2e-07 3MKH-A nrPDB 53 4e-07 1W07-A nrPDB 51 2e-06 5GJ7-A nrPDB 46 4e-05 1IS2-A nrPDB 38 0.014 3KN6-A nrPDB 30 2.9 3FN9-A nrPDB 29 7.5 3JVU-A nrPDB 29 7.9 3U2O-A nrPDB 28 9.5 >3B96-A nrPDB Length = 587 Score = 1204 bits (3116), Expect = 0.0, Method: Compositional matrix adjust. Identities = 587/587 (100%), Positives = 587/587 (100%) Query: 69 ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMV 128 ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMV Sbjct: 1 ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMV 60 Query: 129 EETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKG 188 EETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKG Sbjct: 61 EETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKG 120 Query: 189 ILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL 248 ILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL Sbjct: 121 ILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL 180 Query: 249 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA 308 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA Sbjct: 181 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA 240 Query: 309 EVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ 368 EVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ Sbjct: 241 EVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ 300 Query: 369 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK 428 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK Sbjct: 301 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK 360 Query: 429 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG 488 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG Sbjct: 361 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG 420 Query: 489 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE 548 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE Sbjct: 421 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE 480 Query: 549 AKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCI 608 AKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCI Sbjct: 481 AKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCI 540 Query: 609 EAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF 655 EAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF Sbjct: 541 EAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF 587 >2Z1Q-A nrPDB Length = 577 Score = 298 bits (764), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 192/471 (40%), Positives = 257/471 (54%), Gaps = 61/471 (12%) Query: 138 ELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDL----GVGITLGAHQSIGFKGILLFG 193 ELG + VP E GG+ L +++ V +L G +T GAH SIG ++ FG Sbjct: 71 ELGLLAIDVPEEYGGLDL-----PKVISTVVAEELSGSGGFSVTYGAHTSIGTLPLVYFG 125 Query: 194 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 253 T+ QK KYLPKLASGE +AA+CLTEP SGSDA + +T A S GK+Y LNG K WISN Sbjct: 126 TEEQKRKYLPKLASGEWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNA 185 Query: 254 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 313 G A +FTVFAK E TAF+VER G++ GP EKKMGIKAS+T +V + Sbjct: 186 GFAHLFTVFAKVD---------GEHFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILE 236 Query: 314 GVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKI 373 V+VP ENVLGE+G G K+A ++LN GR+ + A G + + + +AT R QFG I Sbjct: 237 DVKVPVENVLGEIGKGHKIAFNVLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPI 296 Query: 374 HNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ-------------GATDFQIEAAISKI 420 FGLIQ+KL M Y ES Y +D+ G ++ +EA+I K+ Sbjct: 297 GRFGLIQQKLGEMASRIYAAESAVYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKV 356 Query: 421 FGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDK 480 GSE V DE +QI GG G+ +E +ER RD RI RIFEGTN+I RL + G + Sbjct: 357 LGSEVLDYVVDEGVQIHGGYGYSQEYPIERAYRDARINRIFEGTNEINRLLIP--GML-- 412 Query: 481 GKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELA---V 537 L ALK L L +A ++L++ L+ P +L V Sbjct: 413 ------LRRALKGQ-----LPLMQAAQRLQKE-----------LLEPSFEEPEDLELHQV 450 Query: 538 RALEQFATVVEAKLI-KHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASR 587 + L++ A +V + K+ +G+ EQ +L +AD ID YA L RA R Sbjct: 451 QNLKKLALMVAGLAVQKYGQGVEEEQEVLGAVADILIDAYAAESALLRARR 501 >3OWA-A nrPDB Length = 597 Score = 264 bits (674), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 189/573 (32%), Positives = 272/573 (47%), Gaps = 89/573 (15%) Query: 81 QLTTDQVFPYPSVLNEEQTQFLKE----LVEPVSRFFEEVNDPAKNDALEMVEETTWQGL 136 ++T DQVF P + E K +V V E + + ++ +++E Sbjct: 21 EITIDQVFT-PEDFSSEHKMIAKTTEDFIVNEVLPELEYLEQHEFDRSVRLLKEAG---- 75 Query: 137 KELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKA 196 ELG G VP E GG+GL A + E G IT GAH IG I+LFG + Sbjct: 76 -ELGLLGADVPEEYGGIGLDKVSSALIAEKFSRAG-GFAITHGAHVGIGSLPIVLFGNEE 133 Query: 197 QKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLA 256 QK+KYLP LA+GE +AA+ LTEP SGSDA +T+A + G +Y LNG K WI+N A Sbjct: 134 QKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTARLNAEGTHYVLNGEKQWITNSAFA 193 Query: 257 DIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVR 316 D+F V+AK E +AF+VE+ + G++ P EKKMGIK S+T + + Sbjct: 194 DVFIVYAKID---------GEHFSAFIVEKDYAGVSTSPEEKKMGIKCSSTRTLILEDAL 244 Query: 317 VPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNF 376 VP EN+LGE+G G +A +ILN GR+ + G+ + + + +A R QF + I F Sbjct: 245 VPKENLLGEIGKGHIIAFNILNIGRYKLGVGTVGSAKRAVEISAQYANQRQQFKQPIARF 304 Query: 377 GLIQEKLARMVMLQYVTESMAY----MVSANMDQ--------------GATDFQIEAAIS 418 LIQEKLA M Y ES Y + + M ++ IE +++ Sbjct: 305 PLIQEKLANMAAKTYAAESSVYRTVGLFESRMSTLSEEEVKDGKAVAASIAEYAIECSLN 364 Query: 419 KIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV------ 472 K+FGSE DE +QI GG GFM E +ER+ RD RI RIFEGTN+I RL V Sbjct: 365 KVFGSEVLDYTVDEGVQIHGGYGFMAEYEIERMYRDSRINRIFEGTNEINRLIVPGTFLR 424 Query: 473 -ALQG---CMDKGKELSGLGSAL------KNPFGNAGLLLGEAGKQLRRRAGLGSGLSLS 522 A++G + K ++L + P L+ A K GL ++ Sbjct: 425 KAMKGELPLLQKAQKLQEELMMMMPEEVGDEPLALQKYLVNNAKK---------IGLMVA 475 Query: 523 GLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVL 582 GL K+ K + EQ +L +AD +LYAM + Sbjct: 476 GLAAQ-------------------------KYGKALDKEQEILVNIADIVSNLYAMESAV 510 Query: 583 SRASRSL-SEGHPTAQHEKMLCDTWCIEAAARI 614 R +++ + G + + + + +C EA I Sbjct: 511 LRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEI 543 >5LNX-A nrPDB Length = 379 Score = 252 bits (643), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 153/383 (39%), Positives = 221/383 (57%), Gaps = 16/383 (4%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQ---VPSEL 150 + +EQ ++++V +R +E+ A + +E +E +Q +K++G GL VP + Sbjct: 3 VTQEQV-MMRKMVRDFAR--KEIAPAA--EIMEKTDEFPFQLIKKMGKHGLMGIPVPEQY 57 Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET 210 GG G Y + + VG+ L H S+G IL FG + QK KY+P LASG+ Sbjct: 58 GGAGADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDH 117 Query: 211 VAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDP 270 + AF LTEP SGSDA S+RT+A+ GKY LNGSK++I+NGG ADI+ FA +T P Sbjct: 118 LGAFALTEPHSGSDAGSLRTTAIKK-NGKY-LLNGSKIFITNGGAADIYITFA---LTAP 172 Query: 271 ATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 G + I+AF+VE+ G T G E+K+G+ SNT E+ FD VP N+LG+ G GF Sbjct: 173 DQG--RHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGF 230 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 +AM LN GR G+AA G + AVD+A R QFG I I KLA M Sbjct: 231 HIAMANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRA 290 Query: 391 YVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVER 450 + Y +A++ + EA+++K F S+AA K + +QI GG G+MK+ VER Sbjct: 291 EAARHLVYH-AADLHNRGLNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVER 349 Query: 451 VLRDLRIFRIFEGTNDILRLFVA 473 +LRD ++ +I+EGTN+I RL ++ Sbjct: 350 LLRDAKVTQIYEGTNEIQRLIIS 372 >5OL2-C nrPDB Length = 378 Score = 238 bits (607), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 146/381 (38%), Positives = 219/381 (57%), Gaps = 11/381 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKN-DALEMVEETTWQGLKELGAFGLQVPSELGG 152 LN ++ Q LKEL VS EV A D E T + + + G G+ P E GG Sbjct: 3 LNSKKYQMLKELY--VSFAENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGG 60 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVA 212 G Y VE + G+ L AH S+G I +G + QK+K+L LASGE + Sbjct: 61 EGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLG 120 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 AF LTEP++G+DA+ +T+AV G Y LNGSK++I+N DI+ V A +TD + Sbjct: 121 AFGLTEPNAGTDASGQQTTAVLD--GDEYILNGSKIFITNAIAGDIYVVMA---MTDKSK 175 Query: 273 GAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKV 332 G + I+AF+VE+G G + G EKKMGI+ S T+E+ F+ R+P EN+LG+ G GFK+ Sbjct: 176 G--NKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKI 233 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYV 392 AM L+ GR G+AA G +G + + V + R QFG + F Q +LA M + Sbjct: 234 AMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQA 293 Query: 393 TESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452 + Y + N D G + +EAA++K+F +E A +VT + +Q+ GG G+ ++ VER++ Sbjct: 294 ARHLVYQAAINKDLGKP-YGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMM 352 Query: 453 RDLRIFRIFEGTNDILRLFVA 473 RD +I I+EGT+++ R+ ++ Sbjct: 353 RDAKITEIYEGTSEVQRMVIS 373 >1BUC-A nrPDB Length = 383 Score = 235 bits (599), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 136/308 (44%), Positives = 188/308 (61%), Gaps = 7/308 (2%) Query: 160 YARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEP 219 Y VE + +D GV ITL A S+ I FGT+AQKEK+L L G + AF LTEP Sbjct: 72 YILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEGTKLGAFGLTEP 131 Query: 220 SSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKI 279 ++G+DA+ +T A + G Y TLNGSK++I+NGG ADI+ VFA +TD + G I Sbjct: 132 NAGTDASGQQTIATKNDDGTY-TLNGSKIFITNGGAADIYIVFA---MTDKSKG--NHGI 185 Query: 280 TAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNN 339 TAF++E G G T+G E KMGI S T E+ F V+VP+EN+LGE G GFK+AM L+ Sbjct: 186 TAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGKGFKIAMMTLDG 245 Query: 340 GRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYM 399 GR G+AA G +A AV+++ R QFG+ + F I KLA M M ++ Y Sbjct: 246 GRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKMQIEAARNLVYK 305 Query: 400 VSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFR 459 + +G F ++AAI+K S+ A +VT E +QI GG G+ +E V R +RD +I + Sbjct: 306 AACKKQEGKP-FTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPVARHMRDAKITQ 364 Query: 460 IFEGTNDI 467 I+EGTN++ Sbjct: 365 IYEGTNEV 372 >4L1F-A nrPDB Length = 383 Score = 233 bits (594), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 148/391 (37%), Positives = 217/391 (55%), Gaps = 14/391 (3%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPA--KNDALEMVEETTWQGLKELGAFGLQVPSELG 151 L E+Q Q +K++ + F E+ P + D + + + E G G+ P E G Sbjct: 5 LTEDQ-QMIKDMA---AEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G+GL Y VE + D G GITL A+ S+ I +FGT+ QK+KYL +A G V Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 AF LTEPS+G+DA++ +T+AV G Y LNGSK++I+NG AD + VFA +TD + Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVLK--GDKYILNGSKIFITNGKEADTYVVFA---MTDKS 175 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 G I+AF++E+G G G E KMG S TAE+ F+ VP EN+LG+ G GFK Sbjct: 176 QGV--HGISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFK 233 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 +AM L+ GR G+AA G G +A AV ++ R QFG I F +Q +A M Sbjct: 234 IAMETLDGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIE 293 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 + Y + ++G + AA++K F S+ A +VT + +QI GG G+ + ER Sbjct: 294 AARYLVYHAAMLKNEGKP-YSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERY 352 Query: 452 LRDLRIFRIFEGTNDILRLFVALQGCMDKGK 482 +R+ +I +I+EGTN ++R+ + DK K Sbjct: 353 MRNAKITQIYEGTNQVMRIVTSRALLRDKKK 383 >1UKW-A nrPDB Length = 379 Score = 226 bits (577), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 148/391 (37%), Positives = 214/391 (54%), Gaps = 33/391 (8%) Query: 94 LNEEQTQ-------FLKELVEPVSRFFEEVNDPAKNDALEMVEETTW---QGLKELGAFG 143 L EEQ Q F KE++ PV++ ++E EE W + L E+G Sbjct: 5 LTEEQRQLQALARRFAKEVILPVAQEYDEK------------EEVPWPVIEKLHEVGLLN 52 Query: 144 LQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLP 203 +P E GG+GL + E + +G+ T+ +G +LL GT+ QKE++L Sbjct: 53 AIIPEEYGGMGLKMLDEVIVGEELAYACMGI-YTIPMASDLGITPVLLAGTEEQKERFLR 111 Query: 204 KLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFA 263 L +AAF L+EP +GSDAA+++T A+ G +Y LNG+K+WISNGG A+ VFA Sbjct: 112 PLTEKPALAAFALSEPGNGSDAAALKTRAIRQ--GDHYVLNGTKMWISNGGEAEWVVVFA 169 Query: 264 KTPVTDPATGAVKEK-ITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENV 322 +P ++ K + A VVERG G KMG +AS T E+ F+ V+VP EN Sbjct: 170 ---TVNPE---LRHKGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENR 223 Query: 323 LGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEK 382 LGE G GFK+AM LN R +AA G R + +A +A R FGE I NF IQ K Sbjct: 224 LGEEGEGFKIAMQTLNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFK 283 Query: 383 LARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGF 442 L M++ Y + DQG +AI+K + SE A++ ++ IQI GG G+ Sbjct: 284 LVDMLIGIETARMYTYYAAWLADQGLPHAH-ASAIAKAYASEIAFEAANQAIQIHGGYGY 342 Query: 443 MKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 ++E VE++LRD+++ +I+EGTN+I RL +A Sbjct: 343 VREFPVEKLLRDVKLNQIYEGTNEIQRLIIA 373 >2CX9-A nrPDB Length = 387 Score = 224 bits (572), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 136/338 (40%), Positives = 199/338 (58%), Gaps = 4/338 (1%) Query: 136 LKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTK 195 L E G FG VP GG GL +AR+VE + +D + +T+ +H S+ ILL G++ Sbjct: 47 LAEFGVFGALVPEAYGGAGLSTRLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSE 106 Query: 196 AQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGL 255 AQKE +LPKLASGE + A+ LTEP SGSDAA+++T A G + LNG+K +I+ G + Sbjct: 107 AQKEAFLPKLASGEALGAWGLTEPGSGSDAAALKTKAEKVEGG--WRLNGTKQFITQGSV 164 Query: 256 ADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGV 315 A ++ V A+T P+ + I+AF R G+ G E+K+G+ AS+TA++ + + Sbjct: 165 AGVYVVMARTD-PPPSPERKHQGISAFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDL 223 Query: 316 RVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHN 375 VP E +LGE G GF + +L+ GR G+AA G + + A+ +A R FG I Sbjct: 224 FVPEEALLGERGKGFYDVLRVLDGGRIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAE 283 Query: 376 FGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQ 435 F + KLA + Y+ +A + F +EAA +K+F SEAA K DE IQ Sbjct: 284 FEGVSFKLAEAATEL-EAARLLYLKAAELKDAGRPFTLEAAQAKLFASEAAVKACDEAIQ 342 Query: 436 IMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 I+GG G++K+ VER RD R+ RI EGT++IL+L +A Sbjct: 343 ILGGYGYVKDYPVERYWRDARLTRIGEGTSEILKLVIA 380 >4N5F-A nrPDB Length = 385 Score = 223 bits (569), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 135/340 (39%), Positives = 190/340 (55%), Gaps = 8/340 (2%) Query: 136 LKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTK 195 L ELG G+ VP ELGG YA +E V D + H S+G IL FGT Sbjct: 53 LGELGLLGMIVPQELGGSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTP 112 Query: 196 AQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGL 255 AQK+++L +A+G + AFCLTEP +GS+A ++RT A + LNG+K +++NG Sbjct: 113 AQKDRWLADMAAGRVIGAFCLTEPHAGSEANNLRTRAELRD--GQWVLNGAKQFVTNGQR 170 Query: 256 ADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGV 315 A + VFA +TDP G K I+AF+V G G PEKKMGI+AS+T + F+ Sbjct: 171 AGVAIVFA---MTDPEAG--KRGISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENC 225 Query: 316 RVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHN 375 +P +N+LG G G K+A+ L GR G+AA G R KA +A R QFG+ I Sbjct: 226 AIPEDNLLGNRGEGLKIALSNLEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAE 285 Query: 376 FGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQ 435 IQ+KLA M +Q + +A + EA+ +K+F SE A +V + IQ Sbjct: 286 HQAIQQKLADMA-VQINAARLLVHHAAKLRTAGLPCLSEASQAKLFASEMAERVCSDAIQ 344 Query: 436 IMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQ 475 I GG G++ + VER RD RI +I+EGT+++ R+ +A Q Sbjct: 345 IHGGYGYLVDYEVERHYRDARITQIYEGTSEVQRMVIARQ 384 >3PFD-A nrPDB Length = 393 Score = 220 bits (561), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 131/365 (35%), Positives = 205/365 (56%), Gaps = 14/365 (3%) Query: 109 VSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVG 168 ++ + EV++ A+ E L G + VP E GG G + ++E V Sbjct: 38 IAPYAAEVDEKAR------FPEEALAALNSSGFSAIHVPEEYGGQGADSVATCIVIEEVA 91 Query: 169 MHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASI 228 D + + A +G G++L G++ K++ LP +ASGE +A++ L+E +GSDAAS+ Sbjct: 92 RVDCSASL-IPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMASYALSEREAGSDAASM 150 Query: 229 RTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGF 288 RT AV G + LNGSK WI+NGG + +TV A VTDP GA I+AF+V + Sbjct: 151 RTRAVAD--GDDWILNGSKCWITNGGKSTWYTVMA---VTDPDKGA--NGISAFMVHKDD 203 Query: 289 GGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAAL 348 G T GP E+K+GIK S T E++F+ R+P + ++GE G+GFK A+ L++ R + A Sbjct: 204 EGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQA 263 Query: 349 AGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGA 408 G +G + A+ + R QFG + + +Q LA M M M Y +A ++G Sbjct: 264 VGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAARLMVYSAAARAERGE 323 Query: 409 TDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDIL 468 D +A SK F S+ A +VT + +Q+ GG G+ ++ VER++RD +I +I+EGTN I Sbjct: 324 GDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMRDAKITQIYEGTNQIQ 383 Query: 469 RLFVA 473 R+ ++ Sbjct: 384 RVVMS 388 >3NF4-A nrPDB Length = 387 Score = 219 bits (559), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 130/377 (34%), Positives = 211/377 (55%), Gaps = 13/377 (3%) Query: 99 TQFLKELVEPVSRFFEEVNDPA--KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLC 156 +Q EL+E ++V DP +++ E E ++ L G L P E GG G Sbjct: 17 SQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGLLSLPQPEEWGGGGQP 76 Query: 157 NTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCL 216 Y +++E + V + + H S+ +L+FGT+ QK+++LP + SGE + A+ L Sbjct: 77 YEVYLQVLEEIAARWASVAVAVSVH-SLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSL 135 Query: 217 TEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVK 276 +EP +GSDAA++R +A P+ G Y +NGSK WI++GG AD +T+FA+T G Sbjct: 136 SEPQAGSDAAALRCAATPTDGG--YVINGSKSWITHGGKADFYTLFART-------GEGS 186 Query: 277 EKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHI 336 ++ F+V G++ G PE+KMG+ A T F+D R+ ++ +GE G G ++A Sbjct: 187 RGVSCFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSA 246 Query: 337 LNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESM 396 L++GR G+AA G + + +AV +A RT FG KI + + LA M + Sbjct: 247 LDSGRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAAVATARAT 306 Query: 397 AYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 + DQG + +A+I+K+ ++AA KVT + +Q+ GG+G+ ++ VER +R+ + Sbjct: 307 YLDAARRRDQG-RPYSQQASIAKLTATDAAMKVTTDAVQVFGGVGYTRDYRVERYMREAK 365 Query: 457 IFRIFEGTNDILRLFVA 473 I +IFEGTN I RL +A Sbjct: 366 IMQIFEGTNQIQRLVIA 382 >2DVL-A nrPDB Length = 372 Score = 215 bits (547), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 143/378 (37%), Positives = 213/378 (56%), Gaps = 17/378 (4%) Query: 99 TQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLK---ELGAFGLQVPSELGGVGL 155 TQ + +++ V R EV P + + E W LK ELG G+ P E GGVGL Sbjct: 4 TQEQRLVLDAVRRVAREVLYPLAPE-YDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 156 CNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFC 215 + +A +E + D V + + + +L FG++AQK +YL LA GE + AFC Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 216 LTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAV 275 LTEP +GSDA S+R A G + LNG K WI++ G A ++ V A+T Sbjct: 123 LTEPQAGSDAKSLRAEARRVKGG--FVLNGVKSWITSAGHAHLYVVMART---------- 170 Query: 276 KEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMH 335 ++ I+AF+VE+G G++ G PE+KMG+ A++TAEV + V VP EN+LGE G G A+ Sbjct: 171 EKGISAFLVEKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALA 230 Query: 336 ILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTES 395 L++GR G+AA G RG A +A R QFG+K+ I K+A M + + Sbjct: 231 GLDSGRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARA 290 Query: 396 MAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDL 455 + + D+G F +EA+ +K+F S AA +VT E +Q++GG G+ ++ VER RD Sbjct: 291 LVLEAARKKDRG-ERFTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDA 349 Query: 456 RIFRIFEGTNDILRLFVA 473 ++ I+EGT++I RL +A Sbjct: 350 KVTEIYEGTSEIQRLVIA 367 >1JQI-A nrPDB Length = 388 Score = 214 bits (544), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 136/387 (35%), Positives = 204/387 (52%), Gaps = 15/387 (3%) Query: 90 YPSVLNEEQTQFLKELVEPVSRFFEE---VNDPAKNDALEMVEETTWQGLKELGAFGLQV 146 Y SV E Q L++ R F E V A+ D + + + + ELG + V Sbjct: 5 YQSVELPETHQMLRQ----TCRDFAEKELVPIAAQLDKEHLFPTSQVKKMGELGLLAMDV 60 Query: 147 PSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 P EL G GL Y+ +E + G+ + + S+ IL FG+ QK++++ Sbjct: 61 PEELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFT 120 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 +G+ + F L+EP +GSDA + T+A G + LNG+K WI+N A VFA T Sbjct: 121 NGDKIGCFALSEPGNGSDAGAASTTAREE--GDSWVLNGTKAWITNSWEASATVVFASTD 178 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 + G I+AF+V G+T G E K+GI+AS+TA + F+ R+P EN+LGE Sbjct: 179 RSRQNKG-----ISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEP 233 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 G GFK+AM L+ GR G+A+ G + + AV +A NR FG + IQ KLA M Sbjct: 234 GMGFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADM 293 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + + +A + F E+A++K+ SEAA ++ + IQI+GGMG++ E Sbjct: 294 ALALESARLLTWR-AAMLKDNKKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEM 352 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVA 473 ER RD RI I+EGT++I RL +A Sbjct: 353 PAERYYRDARITEIYEGTSEIQRLVIA 379 >2VIG-A nrPDB Length = 391 Score = 212 bits (539), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 126/336 (37%), Positives = 188/336 (55%), Gaps = 10/336 (2%) Query: 139 LGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQK 198 LG + VP ELGG GL YA +E + G+ + + S+ IL FG+K QK Sbjct: 49 LGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQK 108 Query: 199 EKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADI 258 + ++ SG+ + F L+EP +GSDA + T+A G + LNG+K WI+N A Sbjct: 109 QAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAE--GDSWVLNGTKAWITNAWEASA 166 Query: 259 FTVFAKTPVTDPATGAVKEK-ITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRV 317 VFA T A++ K I+AF+V G+T G E K+GI+ S+TA + F+ R+ Sbjct: 167 AVVFAST------DRALQNKSISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRI 220 Query: 318 PSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFG 377 P +++LGE G GFK+AM L+ GR G+A+ G + + AV++A NR FG + Sbjct: 221 PKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQ 280 Query: 378 LIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIM 437 +IQ KLA M + + + +A + F EAA++K+ SEAA ++ + IQI+ Sbjct: 281 VIQFKLADMALALESARLLTWR-AAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQIL 339 Query: 438 GGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 GGMG++ E ER RD RI I+EGT++I RL +A Sbjct: 340 GGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIA 375 >4KTO-A nrPDB Length = 410 Score = 211 bits (538), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 141/392 (35%), Positives = 206/392 (52%), Gaps = 16/392 (4%) Query: 86 QVFPYPSVLNEEQTQFLKELVEPVSRFFEE-----VNDPAKNDALEMVEETTWQGLKELG 140 Q + + LN + + L V RF E +D +++A M + W+ + ELG Sbjct: 21 QSMMFEAGLNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPM---SLWREMGELG 77 Query: 141 AFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEK 200 G+ GG GL + +E + VG++ GAH ++ I G AQK + Sbjct: 78 LLGITADEAHGGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSR 137 Query: 201 YLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFT 260 YLPKL SGE V A ++EP +GSD S++ A G Y LNGSK+WI+NG AD+ Sbjct: 138 YLPKLISGEHVGALAMSEPGAGSDVVSMKLKA--DKRGDRYVLNGSKMWITNGPDADVLV 195 Query: 261 VFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSE 320 V+AKT DPA G ITAF+VE+ F G + G K+G++ SNT+E+ F VP E Sbjct: 196 VYAKT---DPAAG--PRGITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEE 250 Query: 321 NVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQ 380 NVLG VG G KV M L+ R ++A G M + V + R QFG+ I F L+Q Sbjct: 251 NVLGGVGEGVKVLMSGLDYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQ 310 Query: 381 EKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGM 440 KLA M + + Y V+A D+G T + +AA ++ +E A + E IQ +GG Sbjct: 311 GKLADMYVTMNAARAYVYAVAAACDRGETARK-DAAGCILYAAEKATAMALEAIQALGGN 369 Query: 441 GFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 472 G+ + R+LRD +++ I GT++I R+ + Sbjct: 370 GYTNDYPAGRLLRDAKLYEIGAGTSEIRRMLI 401 >1IVH-A nrPDB Length = 394 Score = 209 bits (533), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 127/386 (32%), Positives = 206/386 (53%), Gaps = 20/386 (5%) Query: 94 LNEEQTQ-------FLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQV 146 L+EEQ Q FL+E + P ++ + N+ + + E W+ L LG G+ Sbjct: 13 LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNE------FKNLREF-WKQLGNLGVLGITA 65 Query: 147 PSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 P + GG GL ++ ++E + VG++ GAH ++ ++ G +AQKEKYLPKL Sbjct: 66 PVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLI 125 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 SGE + A ++EP++GSD S++ A G +Y LNG+K WI+NG AD+ V+AK Sbjct: 126 SGEYIGALAMSEPNAGSDVVSMKLKAEKK--GNHYILNGNKFWITNGPDADVLIVYAK-- 181 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 TD A ITAF+VE+G G + K+G++ SNT E+ F+ ++P+ N+LG Sbjct: 182 -TDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHE 240 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 G V M L+ R +A G M+ ++ + + R FG+KI +F L+Q K+A M Sbjct: 241 NKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADM 300 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 Y V+ D+G + A + ++ +E A +V + IQ GG G++ + Sbjct: 301 YTRLMACRQYVYNVAKACDEGHCTAKDCAGVI-LYSAECATQVALDGIQCFGGNGYINDF 359 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFV 472 + R LRD +++ I GT+++ RL + Sbjct: 360 PMGRFLRDAKLYEIGAGTSEVRRLVI 385 >4U83-A nrPDB Length = 382 Score = 207 bits (528), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 126/335 (37%), Positives = 183/335 (54%), Gaps = 8/335 (2%) Query: 139 LGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQK 198 LG G+ P E GG L YA +E + D + H S+G IL FGT+ QK Sbjct: 53 LGFLGMLAPEEWGGSDLDMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQK 112 Query: 199 EKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADI 258 ++LPK+A GE + F LTEP +GSDA++++T A G +Y ++GSK +I++G ++ Sbjct: 113 RRFLPKMACGEWIGGFALTEPQAGSDASALKTRARLD--GDHYVIDGSKQFITSGKNGNV 170 Query: 259 FTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVP 318 VFA VTDPA G K+ I+AF+V G E K+G +S+T + F +RVP Sbjct: 171 VIVFA---VTDPAAG--KKGISAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVP 225 Query: 319 SENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGL 378 EN LG G G+K+A+ L GR G+AA G R A D+A R FG+ I Sbjct: 226 VENRLGAEGEGYKIALANLEGGRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQA 285 Query: 379 IQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMG 438 + +LA M M +A + G EA+++K+ SE A +V IQI G Sbjct: 286 VAFRLADMATRIETARQMVLHAAALREAGKPCL-TEASMAKLVASEMAEQVCSAAIQIHG 344 Query: 439 GMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 G G++ + VER+ RD+R+ +I+EGT+D+ RL +A Sbjct: 345 GYGYLADYPVERIYRDVRVCQIYEGTSDVQRLVIA 379 >2JIF-A nrPDB Length = 404 Score = 206 bits (523), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 124/361 (34%), Positives = 201/361 (55%), Gaps = 11/361 (3%) Query: 109 VSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEI 166 V +F +E P + D +E++ QGL + G G++V E GG G ++E Sbjct: 40 VKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGASFLSTVLVIEE 99 Query: 167 VGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAA 226 + D V + ++ I GT+ QK YLP+L + E V +FCL+E +GSD+ Sbjct: 100 LAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFCLSEAGAGSDSF 158 Query: 227 SIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVER 286 +++T A G YY LNGSK+WIS+ A +F V A DP G + IT+F+V+R Sbjct: 159 ALKTRADKE--GDYYVLNGSKMWISSAEHAGLFLVMANV---DPTIGY--KGITSFLVDR 211 Query: 287 GFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAA 346 G+ G PE K+G++AS+T + F+ V+VP N+LG++G G+K A+ LN GR G+AA Sbjct: 212 DTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNEGRIGIAA 271 Query: 347 ALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ 406 + G +G + + R QFG+++ +F +Q ++A + + Y +A + + Sbjct: 272 QMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYN-AARLLE 330 Query: 407 GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTND 466 F EA+++K + SE A + T +CI+ MGG+G+ K+ VE+ RD +I I+EG ++ Sbjct: 331 AGKPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTIYEGASN 390 Query: 467 I 467 I Sbjct: 391 I 391 >4M9A-A nrPDB Length = 385 Score = 205 bits (521), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 141/384 (36%), Positives = 206/384 (53%), Gaps = 10/384 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 +++ T+ + +++ F EV P A+ D + + + ELG G+ VP++ G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G YA +E + + H S+G +L +GT QKE++L LASG+TV Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 AF LTEP +GS+A ++RT A GK+ LNGSK +++NG A + VFA +TDP Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELRD-GKW-ILNGSKQFVTNGARAGLAIVFA---MTDPD 183 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 G K ++AFVV G G PEKKMGI+AS+T + + +P EN+LG+ G G K Sbjct: 184 EG--KRGLSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLK 241 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 +A+ L GR G+AA G R +A +A R QFG+ I I EKLA M Q Sbjct: 242 IALSNLEGGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMAT-QI 300 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 + +A + EA+ +K+F SE A V + IQI GG GF+ + VER Sbjct: 301 NAARLLTHHAARLRTAGLPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERH 360 Query: 452 LRDLRIFRIFEGTNDILRLFVALQ 475 RD RI +I+EGT+++ R+ +A Q Sbjct: 361 YRDARITQIYEGTSEVQRMVIARQ 384 >6FAH-C nrPDB Length = 379 Score = 203 bits (516), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 128/390 (32%), Positives = 211/390 (54%), Gaps = 34/390 (8%) Query: 97 EQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEET------TWQGLKELGAFGLQVPSEL 150 EQ + +++L +R F E + L+ VEE+ + + G FG+++P L Sbjct: 5 EQNKMIRKL----ARDFAE--KELTTEILDEVEESGEFPQEILDKMAKFGFFGIKIPKSL 58 Query: 151 GGVG-------LCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLP 203 GG G +C ++AR+ + ++ L + S+ +LL GT+ Q EKYL Sbjct: 59 GGSGGDHMSYVICMEEFARVSGVASVY-------LSSPNSLAGGPLLLSGTEEQIEKYLK 111 Query: 204 KLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFA 263 + +G+ AF LTEP +GSDA + T+AV G YY LNG K +I+ L D ++A Sbjct: 112 PIITGKKKLAFALTEPGAGSDAGGMSTTAVD--MGDYYLLNGRKTFITMAPLCDDAVIYA 169 Query: 264 KTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL 323 KT ++ G I+AF+V+ G++ G E KMG+ T+++ + V+VP EN L Sbjct: 170 KTDMSKGTRG-----ISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRL 224 Query: 324 GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKL 383 GEV GF AM L+ GR G+A+ G +G + +A+ +A R QFG++I +F I + Sbjct: 225 GEVNKGFSNAMKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMI 284 Query: 384 ARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFM 443 A M + + Y ++ MD + EA+++K + SE ++ + +QI GG G++ Sbjct: 285 ADMATKLEAAKLLVYNAASLMDNKKNATK-EASMAKFYASEICNEICAKAVQIHGGYGYI 343 Query: 444 KEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 KE VER+ RD R+F I+EGT+ + ++ ++ Sbjct: 344 KEYKVERMYRDCRVFTIYEGTSQVQQMVIS 373 >4O5M-A nrPDB Length = 390 Score = 202 bits (513), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 125/373 (33%), Positives = 199/373 (53%), Gaps = 10/373 (2%) Query: 102 LKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQ 159 ++ L + V RF E P A+ D W+ ELG G+ P + GG G+ Sbjct: 17 IEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYGGAGMGYLA 76 Query: 160 YARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEP 219 + +E + +G++ GAH ++ I G+ Q+ KYLPKL SGE V A ++EP Sbjct: 77 HCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHVGALAMSEP 136 Query: 220 SSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKI 279 +GSD S++ +A G Y LNG+K+WI+NG AD+ V+AKT ++ G I Sbjct: 137 GAGSDVVSMKLAAEKR--GDRYVLNGNKMWITNGPDADVLVVYAKTDLSAGPRG-----I 189 Query: 280 TAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNN 339 +AF++E+GF G + K+G++ SNT E+ F+ VP+EN+LG G G V M L+ Sbjct: 190 SAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVNVLMSGLDY 249 Query: 340 GRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYM 399 R +A G M + V + R QF + I F L+Q KLA M + + + Y Sbjct: 250 ERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFNASRAYVYA 309 Query: 400 VSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFR 459 V+A D+G T + +AA ++ +E A ++ + IQ +GG G++ + R+LRD +++ Sbjct: 310 VAAACDRGETTRK-DAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRLLRDAKLYE 368 Query: 460 IFEGTNDILRLFV 472 I GT++I R+ + Sbjct: 369 IGAGTSEIRRMLI 381 >4IRN-A nrPDB Length = 416 Score = 195 bits (495), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 124/381 (32%), Positives = 199/381 (52%), Gaps = 12/381 (3%) Query: 95 NEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGG-- 152 N +Q QF K++++ + ++D KND E+ WQ E G G +P+ GG Sbjct: 41 NSQQIQFRKKVIQFAQQSL--ISDLIKNDKEEIFNRDAWQKCSEFGVHGWPIPARYGGQE 98 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVA 212 + + T YA G D G+ + AH +L FGT+ QKEKYLP L G +A Sbjct: 99 LDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTFGTEEQKEKYLPLLCRGGWIA 158 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 + TEP +GSD S++T+A G Y LNG K +++NG +AD+F +FA DP+ Sbjct: 159 SHAATEPQAGSDIYSLKTTAQKD--GDKYILNGYKHYVTNGTIADLFIIFA---TIDPSL 213 Query: 273 GAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKV 332 G KE +T F++E+ G+ P KMG++ + E+ + V + N LGE G+G + Sbjct: 214 G--KEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEVSAANRLGEEGTGLAI 271 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYV 392 H + R + AA GTM ++ +++ +A + QFG+ I F L+ KL M + Sbjct: 272 FNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKFQLVANKLVEMKLRLEN 331 Query: 393 TESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452 ++ Y V A M + +EA+++ ++ SEA + E I+I G G++ +ER L Sbjct: 332 AKAYLYKV-AWMKENKQMALLEASMANLYISEAWVQSCLEAIEIHGAYGYLTNTELEREL 390 Query: 453 RDLRIFRIFEGTNDILRLFVA 473 RD + + GT++I R+ +A Sbjct: 391 RDAIASKFYSGTSEIQRVVIA 411 >1RX0-A nrPDB Length = 393 Score = 190 bits (483), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 119/384 (30%), Positives = 197/384 (51%), Gaps = 12/384 (3%) Query: 91 PSV-LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSE 149 PS+ LNEEQ +F K + +R E + A+ D E+ + +LG G+ + ++ Sbjct: 15 PSMGLNEEQKEFQKVAFDFAAR--EMAPNMAEWDQKELFPVDVMRKAAQLGFGGVYIQTD 72 Query: 150 LGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE 209 +GG GL + + E + + H + I FG + Q+ K+ P L + E Sbjct: 73 VGGSGLSRLDTSVIFEALATGCTSTTAYISIHNMCAWM-IDSFGNEEQRHKFCPPLCTME 131 Query: 210 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 A++CLTEP SGSDAAS+ TSA G +Y LNGSK +IS G +DI+ V +T Sbjct: 132 KFASYCLTEPGSGSDAASLLTSAKKQ--GDHYILNGSKAFISGAGESDIYVVMCRTGGPG 189 Query: 270 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG 329 P + I+ VVE+G G++ G EKK+G + T V F+ VP N +G G G Sbjct: 190 P------KGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPVANRIGSEGQG 243 Query: 330 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML 389 F +A+ LN GR +A+ G + DH R QFGE + + +Q LA M Sbjct: 244 FLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYLQFTLADMATR 303 Query: 390 QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 449 M + + + D +++K+F ++ + + ++ +Q+ GG G++K+ V+ Sbjct: 304 LVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGGYGYLKDYAVQ 363 Query: 450 RVLRDLRIFRIFEGTNDILRLFVA 473 + +RD R+ +I EG+N+++R+ ++ Sbjct: 364 QYVRDSRVHQILEGSNEVMRILIS 387 >6ES9-A nrPDB Length = 551 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 125/353 (35%), Positives = 183/353 (51%), Gaps = 24/353 (6%) Query: 125 LEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSI 184 +E++EE L ELG FGL +P E GG+GL + E + +GVG +LG I Sbjct: 202 MEIIEE-----LAELGVFGLTIPEEFGGLGLSKASMVVVTEELSRGYIGVG-SLGTRSEI 255 Query: 185 GFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLN 244 + IL GT+AQK K+LP LASGE ++ TEP++GSD S+RT AV G+ + + Sbjct: 256 AAELILCGGTEAQKAKWLPGLASGEILSTAVFTEPNTGSDLGSLRTRAVRD--GEDWVVT 313 Query: 245 GSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFG---------GITHGP 295 G+K WI++ + T+ A+ TDP T + ++ F+ E+ G G+T G Sbjct: 314 GNKTWITHAQRTHVMTLLAR---TDPETTDWR-GLSMFLAEKEPGTDDDPFPTPGMTGGE 369 Query: 296 PEKKMGIKASNTAEVFFDGVRVPSENVL-GEVGSGFKVAMHILNNGRFGMAAALAGTMRG 354 E +G + E+ FDG R+ EN+L GE G GFK M + R AA G + Sbjct: 370 IE-VLGYRGMKEYELGFDGFRIKGENLLGGEPGRGFKQLMETFESARIQTAARAVGVAQS 428 Query: 355 IIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIE 414 + +A +R QFG+ + F + +KLA M + + + Y + D G +E Sbjct: 429 AAEIGMRYAVDRKQFGKSLIEFPRVADKLAMMAVEIMIARQLTYFSAWEKDHG-RRCDLE 487 Query: 415 AAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDI 467 A ++K+ G+ AW D +QI GG GF E + RVL D RI IFEG +I Sbjct: 488 AGMAKLLGARVAWAAADNALQIHGGNGFALEYAISRVLCDARILNIFEGAAEI 540 >5IDU-A nrPDB Length = 410 Score = 185 bits (469), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 116/310 (37%), Positives = 168/310 (54%), Gaps = 11/310 (3%) Query: 163 LVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSG 222 L E + HD G+ A Q +G I L GT QK +YLP+++ GE +AAF L+EP +G Sbjct: 94 LRETLANHD-GLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEPDAG 152 Query: 223 SDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAF 282 SD A++ A G Y ++G K WISNGG+AD + VFA+T A G I+AF Sbjct: 153 SDVAAMSLQARAE--GDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARG-----ISAF 205 Query: 283 VVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRF 342 +V+ G+ E+ I A + FD RVP +LG G GFK+AM L+ R Sbjct: 206 IVDADTPGLQ--IAERIDVIAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDVFRT 263 Query: 343 GMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSA 402 +AAA G R + + + A +R FG+ + +F L Q KLA+M + + + Y + Sbjct: 264 SVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYRAAW 323 Query: 403 NMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFE 462 DQG + EAA++K SE A +V D +Q+ GGMG VER+ R++R RI+E Sbjct: 324 LRDQG-ENVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALRIYE 382 Query: 463 GTNDILRLFV 472 G ++ +L V Sbjct: 383 GATEVQQLIV 392 >5JSC-A nrPDB Length = 410 Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 115/293 (39%), Positives = 162/293 (55%), Gaps = 10/293 (3%) Query: 180 AHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGK 239 A Q +G I L GT QK +YLP++A+G +AAF L+EP +GSD A++ SA G Sbjct: 110 AMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEPEAGSDVAAMTLSARED--GD 167 Query: 240 YYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKK 299 Y L+G K WISNGG+AD + VFA+T A G I+AFVV+ G+ E+ Sbjct: 168 AYVLDGDKTWISNGGIADFYVVFARTGEAPGARG-----ISAFVVDADTPGLE--IAERI 220 Query: 300 MGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKA 359 I A + F G RVP +LG G GFK+AM L+ R +AAA G R +A+ Sbjct: 221 DVIAPHPLARLHFAGARVPRSQMLGAPGEGFKLAMRTLDIFRTSVAAASLGFARHAMAEG 280 Query: 360 VDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISK 419 V A +R FG+ + +F L Q KLA+M + + + Y + DQG + EAA++K Sbjct: 281 VARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLVYRAAWLRDQG-ENVTREAAMAK 339 Query: 420 IFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 472 SE A +V D +Q+ GGMG VE + R++R RI+EG ++ +L V Sbjct: 340 WHASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRALRIYEGATEVQQLIV 392 >2A1T-A nrPDB Length = 421 Score = 179 bits (455), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 123/346 (35%), Positives = 186/346 (53%), Gaps = 9/346 (2%) Query: 138 ELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQ 197 ELG +P GG+GL + E + GV + + S+G I++ G Q Sbjct: 83 ELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEGN-SLGQMPIIIAGNDQQ 141 Query: 198 KEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLAD 257 K+KYL ++ + A+C+TEP +GSD A I+T A G Y +NG K+WI+NGG A+ Sbjct: 142 KKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMWITNGGKAN 199 Query: 258 IFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRV 317 + + A++ DP A K T F+VE GI G E MG + S+T + F+ V+V Sbjct: 200 WYFLLARSD-PDPKAPANK-AFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFEDVKV 257 Query: 318 PSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFG 377 P ENVL G+GFKVAM + R +AA G + + +A +A R FG+ + Sbjct: 258 PKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLVEHQ 317 Query: 378 LIQEKLARMVMLQYVTESMAYMVSA-NMDQGATDFQIEAAISKIFGSEAAWKVTDECIQI 436 I LA M M + M+Y +A +D G + A+I+K F + A ++ + +QI Sbjct: 318 AISFMLAEMAM-KVELARMSYQRAAWEVDSGRRN-TYYASIAKAFAGDIANQLATDAVQI 375 Query: 437 MGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGK 482 +GG GF E VE+++RD +I++I+EGT+ I RL VA + +DK K Sbjct: 376 LGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREH-IDKYK 420 >2PG0-A nrPDB Length = 385 Score = 179 bits (453), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 127/396 (32%), Positives = 199/396 (50%), Gaps = 29/396 (7%) Query: 94 LNEEQTQFLKE----LVEPVSRFFEEVNDPAKNDALE--MVEETTWQGLKELGAFGLQVP 147 LN ++L+E +F E+ P ND + ++ + W + E G V Sbjct: 2 LNHMTARYLREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWVD 61 Query: 148 SELGGVGLCNTQYARLV------EIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKY 201 + GG+ N +A V E VG +G+G+ H I I +GT+ QK+K+ Sbjct: 62 EKYGGL---NADFAYSVVINEELEKVGSSLVGIGL----HNDIVTPYIASYGTEEQKQKW 114 Query: 202 LPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTV 261 LPK +GE + A +TEP +GSD A+I T+AV G YY +NG K +I+NG AD+ V Sbjct: 115 LPKCVTGELITAIAMTEPGAGSDLANISTTAVKD--GDYYIVNGQKTFITNGIHADLIVV 172 Query: 262 FAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSEN 321 KT DP I+ VVER G T G +K+G+ A +TAE+FF +VP+ N Sbjct: 173 ACKT---DPQAKPPHRGISLLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYN 229 Query: 322 VLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQE 381 +LGE G GF M L R +A A + + + RT FG+++ F +Q Sbjct: 230 LLGEEGKGFYYLMEKLQQERLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQF 289 Query: 382 KLARMVMLQYVTESMAYMVSANMDQGATDFQI--EAAISKIFGSEAAWKVTDECIQIMGG 439 +LA M + + V +++ QI E +++K + +E A +V E +Q+ GG Sbjct: 290 RLAEMATEIALGRT---FVDRVIEEHMAGKQIVTEVSMAKWWITEMAKRVAAEAMQLHGG 346 Query: 440 MGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQ 475 G+M+E + R RD+ + I+ GTN++++ +A Q Sbjct: 347 YGYMEEYEIARRYRDIPVSAIYAGTNEMMKTIIARQ 382 >4IV6-A nrPDB Length = 388 Score = 178 bits (451), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 126/381 (33%), Positives = 186/381 (48%), Gaps = 28/381 (7%) Query: 101 FLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQY 160 F+++ V+PV R E N + E++E +KE+G FGL +P G + Y Sbjct: 21 FVEKQVKPVVRELEHANTYPE----ELIET-----MKEIGIFGLAIPEPYGFGAVSMPCY 71 Query: 161 ARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPS 220 ++ E + + + +G H + K +LLFGT+ QK+KYLP++A+GE A LTEP Sbjct: 72 VQVAEELARGWMSLAGAMGGHTVVS-KLLLLFGTEEQKQKYLPRMATGELRATMALTEPG 130 Query: 221 SGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKT-PVTDPATGAVK--- 276 GSD ++RT V G Y +NGSK WISN +D+ + KT P PA V Sbjct: 131 GGSDLQAMRT--VARRDGDDYVINGSKTWISNARRSDLVALMCKTDPDAQPAHKGVSILL 188 Query: 277 -EKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLG-EVGSGFKVAM 334 EK+ F V R K+G K + E+ F RVP ++LG + G GF M Sbjct: 189 VEKVPGFDVSRDL---------PKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFAQMM 239 Query: 335 HILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTE 394 L GR +AA G R A+ ++ R FG+ I + LA M Y Sbjct: 240 KGLEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLYAAR 299 Query: 395 SMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRD 454 S+ + D G +EA ++K+F SE A ++ + +++ GG G+ E VER RD Sbjct: 300 SLLLSAAEKFDAGQR-CDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERYFRD 358 Query: 455 LRIFRIFEGTNDILRLFVALQ 475 + + EGTN+I R +A Q Sbjct: 359 APLMIVGEGTNEIQRNVIAKQ 379 >3MPI-A nrPDB Length = 397 Score = 176 bits (446), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 124/385 (32%), Positives = 199/385 (51%), Gaps = 12/385 (3%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 L++E KE+ V++ D N+ EE + + ELG FG +P E GG Sbjct: 5 LSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAV-RPMGELGFFGTVIPEEYGGE 63 Query: 154 GLCNTQYARLV--EIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G+ A ++ E + + + L IL +G++A K+KY+PKL+S E + Sbjct: 64 GMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSAEFL 123 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 F +TEP +GSD ++ ++A G ++ LNGSK WISN AD+ +A TD A Sbjct: 124 GGFGITEPDAGSDVMAMSSTAEDK--GDHWLLNGSKTWISNAAQADVLIYYA---YTDKA 178 Query: 272 TGAVKEKITAFVVE-RGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 G+ ++AFV+E R F GI EK +G AS T E+F D V+VP EN+LG+ G G Sbjct: 179 AGS--RGLSAFVIEPRNFPGIKTSNLEK-LGSHASPTGELFLDNVKVPKENILGKPGDGA 235 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 ++ LN+ R AA G + + A+ + R QFG+ I +F + Q+ +A+M + Sbjct: 236 RIVFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEV 295 Query: 391 YVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVER 450 +AY +A D+G + ++ A++K EA K + ++I+G G+ E V R Sbjct: 296 EAARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVAR 355 Query: 451 VLRDLRIFRIFEGTNDILRLFVALQ 475 RD + + EG+ +I ++ +AL Sbjct: 356 FYRDAPTYYMVEGSANICKMIIALD 380 >3MDE-A nrPDB Length = 385 Score = 172 bits (436), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 110/336 (32%), Positives = 177/336 (52%), Gaps = 6/336 (1%) Query: 138 ELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQ 197 ELG +P GG+GL + E + GV + A+ ++G +++ G Q Sbjct: 48 ELGLMNTHIPESFGGLGLGIIDSCLITEELAYGCTGVQTAIEAN-TLGQVPLIIGGNYQQ 106 Query: 198 KEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLAD 257 ++KYL ++ + A+C+TEP +GSD A I+T A G Y +NG K+WI+NGG A+ Sbjct: 107 QKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMWITNGGKAN 164 Query: 258 IFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRV 317 + + A++ DP A K T F+VE G+ G E MG + S+T + F+ VRV Sbjct: 165 WYFLLARSD-PDPKAPASK-AFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRV 222 Query: 318 PSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFG 377 P ENVL G+GFK+AM + R +AA G + + +A +A R FG+ + Sbjct: 223 PKENVLTGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQ 282 Query: 378 LIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIM 437 I LA M M + + +D G + A+I+K + ++ A ++ + +Q+ Sbjct: 283 GISFLLADMAMKVELARLSYQRAAWEIDSGRRN-TYYASIAKAYAADIANQLATDAVQVF 341 Query: 438 GGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 GG GF E VE+++RD +I++I+EGT I R+ +A Sbjct: 342 GGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRIIIA 377 >3GNC-A nrPDB Length = 399 Score = 170 bits (430), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 115/347 (33%), Positives = 171/347 (49%), Gaps = 10/347 (2%) Query: 126 EMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIG 185 E + ++ + E+G G +P + GG GL Y + V D G + S+ Sbjct: 52 ETTDAAIFREMGEIGLLGPTIPEQYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLV 111 Query: 186 FKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNG 245 I FG+ AQKEKYLPKLA+GE + F LTEP+ GSD S+ T A P G Y+L+G Sbjct: 112 MVPIFEFGSDAQKEKYLPKLATGEWIGCFGLTEPNHGSDPGSMVTRARKVPGG--YSLSG 169 Query: 246 SKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKAS 305 SK+WI+N +AD+F V+AK +++I F++E+G G++ K+G++AS Sbjct: 170 SKMWITNSPIADVFVVWAKLDEDG------RDEIRGFILEKGCKGLSAPAIHGKVGLRAS 223 Query: 306 NTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATN 365 T E+ D VP EN+L V G + LN+ R+G+A G A + + Sbjct: 224 ITGEIVLDEAFVPEENILPHV-KGLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLD 282 Query: 366 RTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEA 425 R QFG + LIQ+KLA M + + D+G +I +I K Sbjct: 283 RKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGTAAVEI-TSIMKRNSCGK 341 Query: 426 AWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 472 A + ++GG G E GV R L +L + +EGT+DI L + Sbjct: 342 ALDIARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALIL 388 >1SIR-A nrPDB Length = 394 Score = 150 bits (379), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 111/347 (31%), Positives = 171/347 (49%), Gaps = 29/347 (8%) Query: 136 LKELGAFGLQVPS--ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFG 193 + E+G G+ P+ G G+ + Y L + D G + S+ I +G Sbjct: 53 ISEMGELGVLGPTIKGYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYG 112 Query: 194 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 253 ++ Q++KYLP+LA GE + F LTEP+SGSD +S+ T A + K YTLNG+K WI+N Sbjct: 113 SEEQRQKYLPQLAKGELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNS 172 Query: 254 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 313 +AD+F V+A+ G ++ F++E+G G++ + K ++AS T + D Sbjct: 173 PMADLFVVWARC-----EDGCIR----GFLLEKGMRGLSAPRIQGKFSLRASATGMIIMD 223 Query: 314 GVRVPSENVL---GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFG 370 GV VP ENVL +G F LNN R+G+A + G + A +A +R QFG Sbjct: 224 GVEVPEENVLPGASSLGGPFGC----LNNARYGIAWGVLGASEFCLHTARQYALDRMQFG 279 Query: 371 EKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAA-----ISKIFGSEA 425 + LIQ+KLA M +TE + + A + G Q +AA + K Sbjct: 280 VPLARNQLIQKKLADM-----LTE-ITLGLHACLQLGRLKDQDKAAPEMVSLLKRNNCGK 333 Query: 426 AWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 472 A + + ++GG G E V R +L +EGT+DI L + Sbjct: 334 ALDIARQARDMLGGNGISDEYHVIRHAMNLEAVNTYEGTHDIHALIL 380 >6CY8-B nrPDB Length = 380 Score = 149 bits (377), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 111/384 (28%), Positives = 182/384 (47%), Gaps = 14/384 (3%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELG-- 151 +N E T EL E RF +E++ P + D W L + G FGL +P + Sbjct: 1 MNFEWTHEQAELFEHALRFGKELSAPLQED--NGFPRDNWNALGDFGYFGLPIPEKYAKD 58 Query: 152 GVGLCNTQYARLVEIVGMH--DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE 209 G G +++E +G D G+ AH IL G++ K + LP LA+G Sbjct: 59 GSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLATGR 118 Query: 210 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 +AA ++E S+GSD +++ T+A G YY LNG K +++NG +AD + V+A T Sbjct: 119 KIAANAISEASAGSDISNLATTAQKE--GDYYVLNGGKSYVTNGSIADYYVVYATTNKKH 176 Query: 270 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG 329 G TAFVV R GI+ G K+G++++ +VFFD + + LG G G Sbjct: 177 GYLGQ-----TAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQG 231 Query: 330 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML 389 ++ ++ R + A G M+ + + +++A R Q + I F + ++A M + Sbjct: 232 ARIFAASMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVR 291 Query: 390 QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 449 M Y + Q D A+SK+ SEA + + I++ G +G++ E V Sbjct: 292 LESARLMLYYAAWQKSQD-VDNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVN 350 Query: 450 RVLRDLRIFRIFEGTNDILRLFVA 473 ++D +F GT+DI R + Sbjct: 351 NSIKDALGSVLFSGTSDIQRELIC 374 >4W9U-A nrPDB Length = 395 Score = 148 bits (374), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 113/386 (29%), Positives = 180/386 (46%), Gaps = 17/386 (4%) Query: 91 PSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETT----WQGLKELGAFGLQV 146 P +L E+ T+ + + + F +V P A +EETT + + + G G+ + Sbjct: 12 PFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAY--LEETTDPELFHLMGQAGLLGVTL 69 Query: 147 PSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 P + G Y + V D G + S+ I +G+ Q++KYLP L Sbjct: 70 PEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLV 129 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 SGE + F LTEP +GSD A ++T A G Y L+GSK+WISN +AD+F V+AK+ Sbjct: 130 SGELIGCFGLTEPDAGSDPAGMKTRAEKIDGG--YRLSGSKMWISNSPIADVFVVWAKSA 187 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 D A I F++E+G G++ K+ ++AS T E+ DGV V + +L V Sbjct: 188 AHDNA-------IRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAILPNV 240 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 SG K LN R+G++ + G +A + +R QF + + L Q+KLA M Sbjct: 241 -SGLKGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADM 299 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + V D+G ++ +I K A + + + GG G E Sbjct: 300 QTEIALGIQASLRVGRLFDEGKMAPEM-ISIVKRNNCGKALDIARQARDMHGGNGIQIEY 358 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFV 472 V R ++L +EGT+D+ L + Sbjct: 359 HVMRHAQNLETVNTYEGTHDVHALIL 384 >3SF6-A nrPDB Length = 403 Score = 146 bits (369), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 116/413 (28%), Positives = 189/413 (45%), Gaps = 40/413 (9%) Query: 85 DQVFPYPSVLNEEQTQF-------LKELVEP-VSRFFEEVNDPAKNDALEMVEETTWQGL 136 D + +VL+ E+ + ++ ++P ++ ++E+ PA+ A+E L Sbjct: 21 DDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVE---------L 71 Query: 137 KELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKA 196 ELG G+ + G G+ Y + D G+ + S+ I FG+ Sbjct: 72 GELGLLGMHLKG-YGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAIHAFGSDE 130 Query: 197 QKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLA 256 QK+++LP +ASG + F LTEP GSD A +RT A S G + L G+K+WI+NG +A Sbjct: 131 QKDQWLPDMASGHRIGCFGLTEPDHGSDPAGMRTRATRS--GDDWILTGTKMWITNGSVA 188 Query: 257 DIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVR 316 D+ V+A+T E I FVV G T + KM ++AS T+E+ DGVR Sbjct: 189 DVAVVWART----------DEGIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVR 238 Query: 317 VPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNF 376 +P L S + LN RFG+ G R + A+ +A +R QF I F Sbjct: 239 LPDSARLPGATS-LGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGF 297 Query: 377 GLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQI 436 L Q+KLA M + +A + D G + + ++ K+ A ++ + Sbjct: 298 QLTQQKLADMTLEYGKGFLLALHLGRQKDAGELAPE-QVSLGKLNNVREAIEIARTARTV 356 Query: 437 MGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 489 +G G E V R +L +EGT+++ L + G+ L+G+G+ Sbjct: 357 LGASGITGEYPVMRHANNLESVLTYEGTSEMHTLII--------GQALTGVGA 401 >5ZW7-A nrPDB Length = 402 Score = 144 bits (362), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 107/377 (28%), Positives = 185/377 (49%), Gaps = 18/377 (4%) Query: 104 ELVEPVSRFFEEV--NDPAKNDALEMVEETTWQGLKELGAFGLQ---VPSELGGVGLCNT 158 ++ E RF +V D + +++ W K+ A+G V + GG L Sbjct: 11 DIYESAYRFACDVLDQDAQTRISQKILSTELW---KKAAAYGFAHGPVSHQFGGSELGAL 67 Query: 159 QYARLVEIVGM--HDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCL 216 A ++E +G D+G+ +L AH + FG+ K+KYL L +G+ +AA Sbjct: 68 DTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGKLIAANAA 127 Query: 217 TEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVK 276 TEP +GSD +++ +A PC Y LNG K++I+N +AD+F ++AK T+P G + Sbjct: 128 TEPDAGSDIYNMQATA--QPCEGGYILNGKKIFITNAPIADVFIIYAK---TNPDHGFL- 181 Query: 277 EKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHI 336 ++AF++E+G G+ G K + +E+ F+ + +P +G G+G + Sbjct: 182 -GVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAGGAIFHDS 240 Query: 337 LNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESM 396 + + ++A G + ++ +++A R QFG+ I F + ++ M + M Sbjct: 241 MIWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLRLEQCRLM 300 Query: 397 AYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 Y DQG D + + A+SK+ SE A + + IQ GG +E G+ R L ++ Sbjct: 301 LYRACWKHDQG-QDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLVRHLLNMI 359 Query: 457 IFRIFEGTNDILRLFVA 473 RIF GTNDI + +A Sbjct: 360 PSRIFSGTNDIQKEIIA 376 >2EBA-A nrPDB Length = 385 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 113/393 (28%), Positives = 182/393 (46%), Gaps = 30/393 (7%) Query: 103 KELVEPVSRFFEEVNDPAKNDALE--MVEETTWQGLKELGAFGLQVPSELGGVGLCNTQY 160 KE+ + RF E+ P D E + ELG G +P E GG G+ + Y Sbjct: 16 KEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLPPEYGGAGVSSAAY 75 Query: 161 ARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPS 220 + + D G+ + S+ I +G++ QK ++LPKLA GE V F LTEP Sbjct: 76 GLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEMVGCFGLTEPD 135 Query: 221 SGSDA-ASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKI 279 GSD +++T A G + LNG+K+WI+NG LA + ++AK + + Sbjct: 136 GGSDPYGNMKTRARRE--GDTWVLNGTKMWITNGNLAHLAVIWAKDEGGE---------V 184 Query: 280 TAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNN 339 F+V G ++KM ++AS T+E+ + VRVP E++ G K + L Sbjct: 185 LGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVP-ESLRLPKALGLKAPLSCLTQ 243 Query: 340 GRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYM 399 RFG+A G + + +AV A +R+ FGE + L+Q KLA M+ +A+ Sbjct: 244 ARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAWHTEGLLLAWR 303 Query: 400 VSANMDQGATDFQIEAAISKIFGSEAAWKVTDE---CIQIMGGMGFMKEPGVERVLRDLR 456 ++ D+G ++ A + + WK I+GG G E R + +L Sbjct: 304 LARLKDEG----KLTPAQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAIRHMLNLE 359 Query: 457 IFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 489 +EGT+D+ L + G+E++GL + Sbjct: 360 TVYTYEGTHDVHTLVL--------GREITGLNA 384 >3R7K-A nrPDB Length = 403 Score = 137 bits (344), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 116/390 (29%), Positives = 178/390 (45%), Gaps = 27/390 (6%) Query: 89 PYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPS 148 P L++ F++ + P +E V + ++ L E +G G+ P Sbjct: 31 PERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNAAE---------VGLLGIGFPE 81 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILL-----FGTKAQKEKYLP 203 E+GG G A + E + L G + G ++ GI L G+ A E+Y+ Sbjct: 82 EVGGSGGNAIDSALVTEAI----LAAGGSTGVCAALFTHGIALPHIAANGSDALIERYVR 137 Query: 204 KLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFA 263 +G+ + + +TEP +GSD A++RT AV G Y +NG+K +I++G AD T Sbjct: 138 PTLAGKMIGSLGVTEPGAGSDVANLRTRAVRE--GDTYVVNGAKTFITSGVRADFVTTAV 195 Query: 264 KTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL 323 +T P G V + V+++ G KMG + S+TAE+ F VRVP++N++ Sbjct: 196 RT--GGPGYGGV----SLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLV 249 Query: 324 GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKL 383 G SGF M R G+A T + A A R FG + +I+ KL Sbjct: 250 GAENSGFLQIMQQFQAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKL 309 Query: 384 ARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFM 443 A M V + V G D E +++K A V +E +QI GGMG+M Sbjct: 310 AEMARQVDVACTYTRAVMQRWLAG-EDVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYM 368 Query: 444 KEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 +E +ER RD RI I GTN+I+ +A Sbjct: 369 RESEIERHYRDCRILGIGGGTNEIMNEVIA 398 >3SWO-A nrPDB Length = 399 Score = 134 bits (336), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 110/389 (28%), Positives = 177/389 (45%), Gaps = 36/389 (9%) Query: 100 QFLKELVEP-VSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNT 158 QF+ ++P V +FE P+ E+ +E LG G+ + G G Sbjct: 39 QFVDTRLKPNVEGWFESATLPS-----ELAKE-----FGNLGVLGMHLQG-YGCAGTNAV 87 Query: 159 QYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTE 218 Y + D G + S+ I +G++ QK ++LP+LA+G+ + F LTE Sbjct: 88 SYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLTE 147 Query: 219 PSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEK 278 P GS+ A +RT A G + LNG+K+WI+NG LAD+ TV+A+T + Sbjct: 148 PDFGSNPAGMRTRARRD--GSDWILNGTKMWITNGNLADVATVWAQT----------DDG 195 Query: 279 ITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILN 338 I F+V G T +K+ ++AS T+E+ D VR+P+ L + G + LN Sbjct: 196 IRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQL-PLAEGLSAPLSCLN 254 Query: 339 NGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAY 398 RFG+ G R + + + +R F + + N+ L QEKLA M + +A Sbjct: 255 EARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLAI 314 Query: 399 MVSANMD-QGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRI 457 + D +G QI ++ K+ A + EC ++GG G E R +L Sbjct: 315 HLGRIKDAEGVRPEQI--SLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLES 372 Query: 458 FRIFEGTNDILRLFVALQGCMDKGKELSG 486 +EGT+++ L + GK L+G Sbjct: 373 VLTYEGTSEMHLLSI--------GKALTG 393 >2IX5-A nrPDB Length = 436 Score = 124 bits (311), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 99/339 (29%), Positives = 153/339 (45%), Gaps = 20/339 (5%) Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET 210 G GL T A + D + H S+G I L G++AQKEKYLP LA T Sbjct: 109 GCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLPSLAQLNT 168 Query: 211 VAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDP 270 VA + LTEP +GSDA+ + T+A G + +NG K WI N AD+ +FA+ T+ Sbjct: 169 VACWALTEPDNGSDASGLGTTATKVEGG--WKINGQKRWIGNSTFADLLIIFARNTTTN- 225 Query: 271 ATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 +I F+V++ G+ K+G++ ++ V VP E+ L V S F Sbjct: 226 -------QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRLPGVNS-F 277 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 + +L R +A G GI + R QFG + F L Q+KL +M+ Sbjct: 278 QDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKLVQMLGNV 337 Query: 391 YVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVER 450 M + + + G +A++ K + S A + +++GG G + + V + Sbjct: 338 QAMFLMGWRLCKLYETGQMT-PGQASLGKAWISSKARETASLGRELLGGNGILADFLVAK 396 Query: 451 VLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 489 DL +EGT DI L G+E++G+ S Sbjct: 397 AFCDLEPIYTYEGTYDINTLVT--------GREVTGIAS 427 >3P4T-A nrPDB Length = 403 Score = 122 bits (306), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 91/276 (32%), Positives = 129/276 (46%), Gaps = 10/276 (3%) Query: 199 EKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADI 258 + Y+ GE + A +TEP GSD +RT A G +Y +NG+K +I++G AD Sbjct: 130 DTYVRPTLRGEKIGALAITEPGGGSDVGHLRTRA--DLDGDHYVINGAKTYITSGVRADY 187 Query: 259 FTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVP 318 A+T P G V + VV++G G KMG ++S+TAE+ + VRVP Sbjct: 188 VVTAART--GGPGAGGV----SLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVP 241 Query: 319 SENVLGEVGSGFKVAMHILNNGRFGMAA-ALAGTMRGIIAKAVDHATNRTQFGEKIHNFG 377 N++G +GF R G+A A AG R + V+ NR FG + + Sbjct: 242 VANLVGSENTGFAQIAAAFVAERVGLATQAYAGAQR-CLDLTVEWCRNRDTFGRPLISRQ 300 Query: 378 LIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIM 437 +Q LA M V V G T+ E +K EA V ++ +Q+ Sbjct: 301 AVQNTLAGMARRIDVARVYTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLF 360 Query: 438 GGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 GGMG+M E VER RD+RI I GT +IL A Sbjct: 361 GGMGYMAESEVERQYRDMRILGIGGGTTEILTSLAA 396 >5AHS-A nrPDB Length = 401 Score = 113 bits (283), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 104/363 (28%), Positives = 171/363 (47%), Gaps = 31/363 (8%) Query: 126 EMVEETTWQG---LKELGAFGLQVPSELGGVGLCNTQYARLVE-----IVGMHDLGVGIT 177 ++ E+ W L++ G G+ +P+ +GG GL ++E M + V Sbjct: 31 DLTEQYPWDNVAQLRDAGFMGMMLPTSVGGRGLSTLDTVIVIEEMAKACATMGRITVDSN 90 Query: 178 LGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPC 237 LGA IG I +G++ Q + + +G+ A C++EP++GS A+ + T A Sbjct: 91 LGA---IG--AITKYGSEEQIKLAADLVLAGDK-PAICISEPNAGSAASEMTTRA--DKN 142 Query: 238 GKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVV---ERGFGGITHG 294 G +Y LNG K WI+ GG++ + +FA+ V D V++ I AF+ + G G+ G Sbjct: 143 GDHYILNGEKYWITGGGVSKLHLIFAR--VFDDG---VEQGIGAFITVLDDHGPEGLKVG 197 Query: 295 PPEKKMGIKASNTAEVFFDGVRVPSENVL---GEVGSGFKVAMHILNNGRFGMAAALAGT 351 MG++ + F +++ ++ + GF M N R G A G Sbjct: 198 RRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLKRGFAALMSAYNAQRVGAGAVALGI 257 Query: 352 MRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDF 411 + + V + R QFG + F +Q +A M + E+ M+ + G T Sbjct: 258 AQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMSVQ---LEAARLMLRSAAVSGETFP 314 Query: 412 QI-EAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRL 470 I +AA +KIF +E A KVT++ +Q G G+ + +ER +RD R+F I GT ILR Sbjct: 315 DINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNPMERHVRDARMFTIAGGTAQILRT 374 Query: 471 FVA 473 VA Sbjct: 375 QVA 377 >4X28-A nrPDB Length = 400 Score = 99.0 bits (245), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 101/397 (25%), Positives = 183/397 (46%), Gaps = 41/397 (10%) Query: 103 KELVEPVSRFFEEVNDPAKNDALEMVE----------ETTWQGLKELGAFGLQVPSELGG 152 +EL + +F + P + +AL V+ ET Q ++ G L P E GG Sbjct: 10 EELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRD-GWLALGWPKEYGG 68 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVA 212 G + +L+ G + S+ I+ +GT QK +LP++A+G+ Sbjct: 69 QG--RSAMDQLIFTDEAAIAGAPVPFLTINSVA-PTIMAYGTDEQKRFFLPRIAAGDLHF 125 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 + +EP +G+D A++RT+AV G Y +NG K+W S AD + +T ++ Sbjct: 126 SIGYSEPGAGTDLANLRTTAVRD--GDDYVVNGQKMWTSLIQYADYVWLAVRT--NPESS 181 Query: 273 GAVKEK-ITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 GA K + I+ +V G + P G +T+ ++ VRVP N +GE +G+K Sbjct: 182 GAKKHRGISVLIVPTTAEGFSWTPVHTMAG---PDTSATYYSDVRVPVANRVGEENAGWK 238 Query: 332 VAMHILNNGRFGMA--AALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM--- 386 + + LN+ R + A + G +R + A + + G ++ + +Q LAR+ Sbjct: 239 LVTNQLNHERVALVSPAPIFGCLREVREWAQN---TKDAGGTRLIDSEWVQLNLARVHAK 295 Query: 387 -VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKE 445 +L+ + +A S D G + +A+ +K+FG+E A + ++++G +++ Sbjct: 296 AEVLKLINWELASSQSGPKDAGPS--PADASAAKVFGTELATEAYRLLMEVLGTAATLRQ 353 Query: 446 --PG------VERVLRDLRIFRIFEGTNDILRLFVAL 474 PG VER+ R I GTN++ R + + Sbjct: 354 NSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGM 390 >1R2J-A nrPDB Length = 366 Score = 97.1 bits (240), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 93/345 (26%), Positives = 156/345 (45%), Gaps = 23/345 (6%) Query: 136 LKELGAFGL---QVPSELGGVGLCNTQYARLVEIVGMHDLGVGI-TLGAHQSIGFKGILL 191 L LGA GL +V +E GG+GL + + VG L + ++ Q + + Sbjct: 30 LVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVG--SLCSSLRSVMTSQGMAAWTVQR 87 Query: 192 FGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWIS 251 G Q+ +L +L SG+ +AA +E +GSD +++RT G ++G K+W + Sbjct: 88 LGDAGQRATFLKELTSGK-LAAVGFSERQAGSDLSAMRTRVRLD--GDTAVVDGHKVWTT 144 Query: 252 NGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVF 311 AD VF + + +GAV VV G+ K G +A+ A++ Sbjct: 145 AAAYADHLVVFG---LQEDGSGAV------VVVPADTPGVRVERVPKPSGCRAAGHADLH 195 Query: 312 FDGVRVPSENVLGEVGSGFKVAMHI---LNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ 368 D VRVP+ VL GSG + M + L GR +A G +R AV HA R Q Sbjct: 196 LDQVRVPAGAVLA--GSGASLPMLVAASLAYGRKSVAWGCVGILRACRTAAVAHARTREQ 253 Query: 369 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK 428 FG + + L+ +A + + + + S + D+G+ + ++K +E A Sbjct: 254 FGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATILAKHVAAERAAA 313 Query: 429 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 Q++ G + VER RD ++ I EG++++ R+ +A Sbjct: 314 GAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLA 358 >4RM7-A nrPDB Length = 391 Score = 96.7 bits (239), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 77/283 (27%), Positives = 133/283 (46%), Gaps = 9/283 (3%) Query: 192 FGTKAQKEKYLPKLA-SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWI 250 F + AQ + + +G A ++EP +GSD S+RT G +NG+K+++ Sbjct: 103 FASSAQTSPFRTEYQDTGRLSYALAISEPEAGSDTRSMRTHVTRE--GDTLVMNGTKMFV 160 Query: 251 SNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEV 310 +NG A V A D + + + ++V R GI + PE+K+G A V Sbjct: 161 NNGEYAPALLVSAYDKTGDDG----EPEFSFWMVPRSAAGI-YAYPEQKIGQSMLPFATV 215 Query: 311 FFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFG 370 FD V V L GF +L GR AA G + + AV A R FG Sbjct: 216 RFDNVEVKESWRLKGSSKGFSQLYSLLEYGRVFTCAAALGEAQAAMEDAVAWARGREAFG 275 Query: 371 EKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVT 430 ++I + +Q KL M + ++ Y + D+G ++ A+ K + +AA +V Sbjct: 276 QRIADLQQVQMKLTEMEVKLTNMRNLVYGAAREYDRGEHK-RLSVALMKYYVPKAATEVA 334 Query: 431 DECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 + +QI+GG G+++E V + +D R ++ +GT++++ + A Sbjct: 335 SDAMQILGGRGYIQENRVSSIWQDCRGYQFADGTDEVMVVIAA 377 >4HR3-A nrPDB Length = 415 Score = 95.5 bits (236), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 100/345 (28%), Positives = 157/345 (45%), Gaps = 21/345 (6%) Query: 140 GAFGLQVPS-ELGGVGLCNTQYARLVEIVGMHDLGVGI-TLGAHQSIGFKGILLFGTKAQ 197 G + L +P ELGG GL N++YA L E +G + A S + + +G++ Q Sbjct: 71 GLWNLFLPDPELGG-GLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVLHRYGSQEQ 129 Query: 198 KEKYLPKLASGETVAAFCLTEPS-SGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLA 256 KE +L L G+ +AFC+TEP + SDA ++ +AV G +NG K W + G Sbjct: 130 KEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVE--GDEVVINGRKWWSTGVGHP 187 Query: 257 DIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGI--KASNTAEVFFDG 314 D V +TDP + + +V GIT MG + V FD Sbjct: 188 DC-KVIIFMGLTDP-NAHRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGGHGVVSFDN 245 Query: 315 VRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIH 374 VR+P++ + G GF++A L GR A L G + A +RT FG+ + Sbjct: 246 VRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDRTAFGKPLV 305 Query: 375 NFGLIQEKL--ARMVMLQ--YVTESMAYMVSANMDQGATDFQIEAAIS--KIFGSEAAWK 428 N G +E++ AR+ + Q + A+++ GA +A+S K+ A + Sbjct: 306 NLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGAL-----SAVSEIKVAAPNMAQQ 360 Query: 429 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 V D IQI GG G + + + R R+ +G +++ R VA Sbjct: 361 VIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVA 405 >2WBI-A nrPDB Length = 428 Score = 87.0 bits (214), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 95/400 (23%), Positives = 167/400 (41%), Gaps = 22/400 (5%) Query: 100 QFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKEL----GAFGLQVPSELGGVGL 155 F+K+ + P + E +N + + LKE+ G + L +P+ GL Sbjct: 36 HFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGLWNLFLPAV---SGL 92 Query: 156 CNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGIL-LFGTKAQKEKYLPKLASGETVAAF 214 + YA + E G + G +L L+G++ QK+++L L G + F Sbjct: 93 SHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSCF 152 Query: 215 CLTEPS-SGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGG--LADIFTVFAKTPVTDPA 271 C+TEP + SDA +I S Y +NG K W S G I V +T T + Sbjct: 153 CMTEPDVASSDATNIECSIQRDE--DSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSLS 210 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKAS---NTAEVFFDGVRVPSEN-VLGEVG 327 ++ + +V G+ P G + E+ F+ VRVP+ N +LGE G Sbjct: 211 R---HKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGE-G 266 Query: 328 SGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMV 387 GF+++ L GR G + + AT R F +K++ ++ +A Sbjct: 267 RGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESR 326 Query: 388 MLQYVTESMAYMVSANMDQ-GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + + +MD G+ + E A+ K+ A K+ D IQ+ GG G ++ Sbjct: 327 IAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQDY 386 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSG 486 + + R+ R+ +G +++ +A D+ K L+ Sbjct: 387 PLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTA 426 >5EZ3-A nrPDB Length = 573 Score = 85.5 bits (210), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 74/270 (27%), Positives = 134/270 (49%), Gaps = 28/270 (10%) Query: 216 LTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAV 275 +TE G+D + T A P+ G + L G K W + ++D F A+T Sbjct: 213 MTEKQGGTDVRANATRAEPA-IGGAWRLTGHK-WFMSAPMSDAFLTLAQT---------- 260 Query: 276 KEKITAFVVER-GFGGITHG----PPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 KE ++ F++ R G G ++G + K+G +++ ++EV FDG ++G G G Sbjct: 261 KEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGA---LGQMIGSPGEGV 317 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 K M ++ R A A AG MR +A+AV H+ +R FG+ + L+Q LA M + Sbjct: 318 KTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDV 377 Query: 391 YVTESMAYMVSANMDQGATDFQIEAA-------ISKIFGSEAAWKVTDECIQIMGGMGFM 443 +++ ++ D A+D + EAA + K + + A + E ++ +GG G++ Sbjct: 378 AGATALSMRLARAFDMAASD-RAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYI 436 Query: 444 KEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 ++ + R R+ + I+EG+ +++ L VA Sbjct: 437 EDGNLARAYREAPVNAIWEGSGNVMALDVA 466 >4Y9J-A nrPDB Length = 593 Score = 80.1 bits (196), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 86/325 (26%), Positives = 143/325 (44%), Gaps = 23/325 (7%) Query: 191 LFGTKAQKEKYLPKLASGETVAAFC----LTEPSSGSDAASIRTSAVPSPCGKYYTLNGS 246 L+G + + +L S + A+ +TE GSD A + Y L+G Sbjct: 161 LYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTYRLHGY 220 Query: 247 KLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVV----ERG-FGGITHGPPEKKMG 301 K W S+ AD+ A+ +D ++ F++ E G GI + K+G Sbjct: 221 K-WFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRLKNKLG 279 Query: 302 IKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVD 361 K TAE+ DG +G+ G G ++LN R A A G MR II+ A D Sbjct: 280 TKQLPTAELLLDGAIAER---IGDQGRGVAGISNMLNITRIHNAVASLGYMRRIISLARD 336 Query: 362 HATNRTQFGEKIHNFGLIQEKLARM-------VMLQYVTESMAYMVSA--NMDQGATDFQ 412 ++T R FG+ + L LA+M ++L + + + A + D A + Sbjct: 337 YSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVEAMMLR 396 Query: 413 IEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFV 472 + + K++ + A + E I+ GG G+M++ G+ +LRD ++ I+EGT ++L L V Sbjct: 397 LITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNVLSLDV 456 Query: 473 ALQGCMDKGKELSGLGSALKNPFGN 497 L+ K L G ++ GN Sbjct: 457 -LRVFSGKENILLAFGKRVEQLLGN 480 >5YS9-A nrPDB Length = 708 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 102/398 (25%), Positives = 154/398 (38%), Gaps = 69/398 (17%) Query: 165 EIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET--VAAFCLTEPSSG 222 ++ G+ D+G I LG H + I GTK Q + ++ K A+ F +TE G Sbjct: 109 QLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGFYGCFAMTELGHG 168 Query: 223 SDAASIRTSAVPSPCGKYYTLN-----GSKLWISNGGLADIFT-VFAKTPVTDPATGAVK 276 S+ A + T+A + +N +K WI + T FA+ V G Sbjct: 169 SNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFARLLVDGKDYG--- 225 Query: 277 EKITAFVVE-RGFG------GITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL---GEV 326 + FVV+ R GI G KKMG A + + F VR+P +N+L +V Sbjct: 226 --VKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNMLMKYAKV 283 Query: 327 GSGFKVAMHILNN--------GRFGMAAALAGTMRGIIAKAVDHATNRTQFG-------E 371 S KV+ L GR M A + I A+ +A R QFG Sbjct: 284 SSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGTTPGQPET 343 Query: 372 KIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQG-----ATDFQIEAAISK------- 419 KI ++ Q +L ++ Y + A DQ D + + A+ K Sbjct: 344 KIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGKAIVDLKE 403 Query: 420 IFGSEAAWK---------VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRL 470 +F S A K + D+C Q GG G+ G + D + +EG N++L Sbjct: 404 LFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEGDNNVL-- 461 Query: 471 FVALQGCMDKGKEL--SGLGSALKNPFGNAGLLLGEAG 506 C+ G+ L S LG P G++ L G Sbjct: 462 ------CLSMGRGLIQSCLGHRKGKPLGSSVGYLANKG 493 >4XVX-A nrPDB Length = 389 Score = 65.1 bits (157), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 83/348 (23%), Positives = 144/348 (41%), Gaps = 31/348 (8%) Query: 142 FGLQVPSELGGVGLCNTQYA--------RLVEIV----GMHDLGVGITLGAHQSIGFKGI 189 F Q+ LG G+ + ++A +LVE+ + G+G+ + H S + Sbjct: 38 FPRQLIEHLGVCGVFDAKWATDARPDVGKLVELAFALGQLASAGIGVGVSLHDS-AIAIL 96 Query: 190 LLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLW 249 FG + G V +E S GSD + T G + + G K + Sbjct: 97 RRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSRDGG--FEVRGVKKF 154 Query: 250 ISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAE 309 +S +AD V A++ DP + VV ++ P +K+G +TA Sbjct: 155 VSLSPIADHIMVVARSVDHDPTS----RHGNVAVVAVPAAQVSVQTPYRKVGAGPLDTAA 210 Query: 310 VFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQF 369 V D VP++ ++ G+G L + R +A +A + + I + +R QF Sbjct: 211 VCID-TWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRAIGITLARMMSRRQF 269 Query: 370 GEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKI---FGSEAA 426 G+ + Q RM LQ + + Y + +QG + + AA+ G E Sbjct: 270 GQTLFEH---QALRLRMADLQARVDLLRYALHGIAEQGRLELRTAAAVKVTAARLGEE-- 324 Query: 427 WKVTDECIQIMGGMGFM-KEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 V EC+ I GG G++ E + + RD+++ R+ GT+++L VA Sbjct: 325 --VISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVA 370 >4ZYJ-A nrPDB Length = 425 Score = 63.2 bits (152), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 91/402 (22%), Positives = 159/402 (39%), Gaps = 46/402 (11%) Query: 81 QLTTDQVFPYPSVLN-----EEQTQFLKELVEPVSRFFEEVNDPAK-NDALEMVEETTWQ 134 +T V +P VL E +T + L++ + R+ + ++ ND + + Sbjct: 20 HMTKPSVHEHPGVLADNGLCEPKTPAGRRLLDLLERYLPALEAESRDNDREATLPVHLFD 79 Query: 135 GLKELGAFGLQVPSELGGVGLCNTQYARLV--EIVGMHDLGVGITLGAHQSIGFKGILLF 192 +++ G G VP +LGG+G+ + L I G D GV + L S G L F Sbjct: 80 RMRKEGVLGATVPEDLGGLGVHSLHDVALALARIAG-RDAGVALALHMQFSRGLT--LDF 136 Query: 193 -------GTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNG 245 T+ E L ++ +GE V + + T+ + Y LNG Sbjct: 137 EWRHGAPSTRPLAEDLLRQMGAGEAVICGAVKDVRG--------TTVLTRATDGSYRLNG 188 Query: 246 SKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKAS 305 K +S G+A + V + ++ A VV R G+T MG+++S Sbjct: 189 RKTLVSMAGIATHYVVSTRL-----EEAGAPVRLAAPVVARTTPGLTVLDNWDGMGMRSS 243 Query: 306 NTAEVFFDGVRVPSENVL--GEVGSGFKVAMHILNNGRFGMAAALAGTMRGII--AKAVD 361 + ++ FDG V + VL GE G A+ G+ + A+ G GI A+ + Sbjct: 244 GSVDIVFDGCPVDRDRVLPRGEPGVRDDAAL----AGQTVSSIAMLGIYVGIAEAARRIA 299 Query: 362 HATNRTQFGEKIHNFGLIQEKLARMVMLQYVTES-------MAYMVSANMDQGATDFQIE 414 R + G + E AR+ L S +A +S ++ Sbjct: 300 LTELRRRGGAPAGVRTTVAEIDARLFALHTAVASALTTADRLADDLSGDLAARGRAMMTP 359 Query: 415 AAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 +K+ + + V D+C+ ++GG G+ + R+ RD+R Sbjct: 360 FQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVR 401 >5Y9D-A nrPDB Length = 709 Score = 61.2 bits (147), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 100/437 (22%), Positives = 168/437 (38%), Gaps = 81/437 (18%) Query: 96 EEQTQFLKELVEPVSRFFEEVNDPAKN---DALEMVEETTWQGLKELGAFGLQVPSELGG 152 EE+TQ +++++ + R DP + D +++ Q ++ + A + ++ Sbjct: 55 EEETQIVEKIMSSIER------DPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEK 108 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPK--LASGET 210 + L Q + GM D+ L H ++ I GT Q + ++ K +A + Sbjct: 109 LSLWRAQ------LHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQF 162 Query: 211 VAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLN-----GSKLWISNGGLADIFT---VF 262 F +TE GS+ + T+A + +N +K WI GG A T F Sbjct: 163 YGCFAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWI--GGAAHTSTHCVCF 220 Query: 263 AKTPVTDPATGAVKEKITAFVVE-RGFG------GITHGPPEKKMGIKASNTAEVFFDGV 315 AK V G FVV R G++ G KKMG + + F V Sbjct: 221 AKLIVHGKDYGTRN-----FVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNV 275 Query: 316 RVPSENVL------GEVGSGFKVAMHILN-----NGRFGMAAALAGTMRGIIAKAVDHAT 364 R+P +N+L + G K A+ L GR M A + + A+ +A Sbjct: 276 RIPRQNMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYAC 335 Query: 365 NRTQFGE-------KIHNFGLIQEKLARMVMLQYV------------TESMAYMVSANMD 405 R QFG KI ++ Q +L ++ Y E+ +++ N + Sbjct: 336 VRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPN 395 Query: 406 QGATDFQIEAAIS------------KIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLR 453 A +E A++ K F + K+ DEC Q GG G+ G + Sbjct: 396 DPAQKNDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYA 455 Query: 454 DLRIFRIFEGTNDILRL 470 D + +EG N++L L Sbjct: 456 DWVVQCTWEGDNNVLCL 472 >2C12-A nrPDB Length = 439 Score = 60.5 bits (145), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 84/362 (23%), Positives = 151/362 (41%), Gaps = 40/362 (11%) Query: 140 GAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKE 199 G QVP LGG + ++E + + IT+ A ++G ++L + + +E Sbjct: 56 GLIKAQVPIPLGGTMESLVHESIILEELFAVEPATSITIVA-TALGLMPVILCDSPSLQE 114 Query: 200 KYLPKLASGE--TVAAFCLTEPSSGSD-----AASIRTSAVPSPCGKYYTLNGSKLWISN 252 K+L SGE +A+ +EP+ ++ ++T+A G + ++G KLW SN Sbjct: 115 KFLKPFISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTA--RKVGNEWVISGEKLWPSN 172 Query: 253 GG-----LADIFTVFAKT---------PVTDPATGAVKEKITAFVVERGFGGITH--GPP 296 G AD+ V + P DPAT +T + G P Sbjct: 173 SGGWDYKGADLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEP 232 Query: 297 EKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTM---- 352 E I S F VP EN+L G + L F M+AAL G M Sbjct: 233 ELAGHITTSG-PHTRFTEFHVPHENLLCTPG----LKAQGLVETAFAMSAALVGAMAIGT 287 Query: 353 -RGIIAKAVDHATNRTQFGEK-IHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATD 410 R +A+ A + T+ G K I + +KL + + + + ++ A + Sbjct: 288 ARAAFEEALVFAKSDTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALE 347 Query: 411 FQIE---AAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDI 467 ++++ A +KI+ ++ A + + ++ +G + K+ R+L ++ + +F+G N Sbjct: 348 WKVKLEMAMQTKIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIG 407 Query: 468 LR 469 LR Sbjct: 408 LR 409 >3U33-A nrPDB Length = 541 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 66/265 (24%), Positives = 119/265 (44%), Gaps = 21/265 (7%) Query: 216 LTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAV 275 +TE GSD S T A G Y L G K W + +D V A+T A G Sbjct: 184 MTEKQGGSDVMSNTTRAERLEDGSY-RLVGHK-WFFSVPQSDAHLVLAQT-----AGGLS 236 Query: 276 KEKITAFVVERGFGGITHGPPEKKMGIKASNTAEV-FFDGVRVPSENVLGEVGSGFKVAM 334 + F+ + I + K+G +++ + EV F D + +LG G G ++ + Sbjct: 237 CFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAIGW----LLGLEGEGIRLIL 292 Query: 335 HILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTE 394 + RF A MR + A+ HA R FG + L++ L+RM + Sbjct: 293 KMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQPLMRHVLSRMALQLEGQT 352 Query: 395 SMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTD-------ECIQIMGGMGFMKEPG 447 ++ + ++ D+ A EA +++F A + + E ++++GG+G+ +E Sbjct: 353 ALLFRLARAWDRRAD--AKEALWARLFTPAAKFVICKRGMPFVAEAMEVLGGIGYCEESE 410 Query: 448 VERVLRDLRIFRIFEGTNDILRLFV 472 + R+ R++ + I+EG+ +I+ L V Sbjct: 411 LPRLYREMPVNSIWEGSGNIMCLDV 435 >3M9V-A nrPDB Length = 439 Score = 56.6 bits (135), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 80/366 (21%), Positives = 151/366 (41%), Gaps = 44/366 (12%) Query: 120 AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGL----------CNTQYARLVEIVGM 169 A++D T+ L++ G G VP+ELGG+G+ A + + Sbjct: 43 AEHDRDGTFPTDTFDALRKDGLMGATVPAELGGLGVDRLYDVAVALLAVARADASTALAL 102 Query: 170 H-DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASI 228 H L G+TLG G + + E+ L + +G+ V C S D + Sbjct: 103 HMQLSRGLTLGYEWRHGDER-----ARTLAERILRGMVAGDAV--VC----SGIKDHHTA 151 Query: 229 RTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGF 288 T+ P G + L+G K +S + F + A+T TD ++ + VV R Sbjct: 152 VTTLRPDGAGGWL-LSGRKTLVSMAPVGTHFVINARTDGTDG-----PPRLASPVVTRDT 205 Query: 289 GGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL--GEVGSGFKVAMHILNNGRFGMAA 346 G T +G++AS T ++ FD +P+++VL VG+ + G+ + Sbjct: 206 PGFTVLDNWDGLGMRASGTVDIVFDDCPIPADHVLMRDPVGARNDAVL----AGQTVSSV 261 Query: 347 ALAGTMRGIIAKAVDHAT---NRTQFGEKIHNFGLIQEKLARMVMLQ-------YVTESM 396 ++ G G+ A D A R + L+ E +R+ L+ +++ Sbjct: 262 SVLGVYVGVAQAAYDTAVAALERRPEPPQAAALTLVAEIDSRLYALRATAGSALTAADAL 321 Query: 397 AYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 + +S +MD+ +K+ + A ++ +C+ ++GG + + R+LRD++ Sbjct: 322 SADLSGDMDERGRQMMRHFQCAKLAVNRLAPEIVSDCLSLVGGASYTAGHPLARLLRDVQ 381 Query: 457 IFRIFE 462 R + Sbjct: 382 AGRFMQ 387 >2FON-A nrPDB Length = 683 Score = 56.2 bits (134), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 83/352 (23%), Positives = 142/352 (40%), Gaps = 50/352 (14%) Query: 193 GTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYY-----TLNGSK 247 GT Q+EK+LP + + + TE GS+ + T+A P + TL SK Sbjct: 133 GTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDEFVIHSPTLTSSK 192 Query: 248 LWISNGGLADIFT---VFAK--TPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGI 302 W GGL + T V+A+ T D ++ + + G+T G K G Sbjct: 193 WW--PGGLGKVSTHAVVYARLITDGKDYGVNGFIVQLRSLEDHKPLPGVTVGDIGMKFGN 250 Query: 303 KASNTAE---VFFDGVRVPSENVLGEVGSGFKVAMHILNN------------GRFGMAAA 347 A N+ + + FD VR+P + +L V K ++ ++ R + A Sbjct: 251 GAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQLLYGTMVYVRQSIVAD 310 Query: 348 LAGTMRGIIAKAVDHATNRTQFGE-------KIHNFGLIQEK----LARMVMLQYVTESM 396 + M + A ++ R QFG ++ ++ Q + LA ++V E + Sbjct: 311 ASLAMSRAVCIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFPLLASAYAFRFVGEWL 370 Query: 397 AYMVSANMDQ-GATDFQI--EAAIS----KIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 449 ++ + + A DF EA K + A +EC ++ GG G++ G+ Sbjct: 371 KWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEECRKLCGGHGYLCSSGLP 430 Query: 450 RVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLL 501 + +EG N +L+L VA + M K +S LG+ K P G + Sbjct: 431 ELFAVYVPACTYEGDNVVLQLQVA-RFLM---KTISQLGTG-KKPVGTVSYM 477 >3MXL-A nrPDB Length = 395 Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 90/343 (26%), Positives = 143/343 (41%), Gaps = 36/343 (10%) Query: 133 WQGLKELGAFGLQVPSELGGVGLCN-----TQYARLVEI-----VGMH-DLGVGITLGAH 181 ++ +LG G VP+ELGG+GL T RL E + H L G+TL Sbjct: 45 FEQFAKLGLMGATVPAELGGLGLTRLYDVATALMRLAEADASTALAWHVQLSRGLTLTYE 104 Query: 182 QSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYY 241 G + +A E+ L +A GE AA C + DA + T G + Sbjct: 105 WQHGTPPV-----RAMAERLLRAMAEGE--AAVC----GALKDAPGVVTELHSDGAGGWL 153 Query: 242 TLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMG 301 L+G K+ +S +A F V A+ D G+V + VV R G+T +G Sbjct: 154 -LSGRKVLVSMAPIATHFFVHAQRRDDD---GSVFLAVP--VVHRDAPGLTVLDNWDGLG 207 Query: 302 IKASNTAEVFFDGVRVPSENVL--GEVGSGFKVAM---HILNNGRFGMAAALAGTMRGII 356 ++AS T EV FD V ++ +L G VG+ + + + G+ A +A R I Sbjct: 208 MRASGTLEVVFDRCPVRADELLERGPVGARRDAVLAGQTVSSITMLGIYAGIAQAARDIA 267 Query: 357 AKAVDHATNRTQFGEKIHNFGLIQEKLA-RMVMLQYVTESMAYMV--SANMDQGATDFQI 413 + G + GL A R + +T + A V S + D+ Sbjct: 268 VGFCAGRGGEPRAGARALVAGLDTRLYALRTTVGAALTNADAASVDLSGDPDERGRRMMT 327 Query: 414 EAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 +K+ +E A V D+C+ ++GG+ + + R+ RD+R Sbjct: 328 PFQYAKMTVNELAPAVVDDCLSLVGGLAYTAGHPLSRLYRDVR 370 >5XDD-A nrPDB Length = 414 Score = 54.7 bits (130), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 54/197 (27%), Positives = 85/197 (43%), Gaps = 14/197 (7%) Query: 134 QGLKELGAFGLQVPSELGGVG-LCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLF 192 ++ G L + E GG+G T Y + EI D +G G H S F + LF Sbjct: 47 DAIRRSGLLTLLISKERGGLGESWPTVYEAIAEIASA-DASLGHLFGYHFS-NFAYVDLF 104 Query: 193 GTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASI--RTSAVPSPCGKYYTLNGSKLWI 250 + QK ++ P+ + L SS ++A + R +A P P G Y +NG+K + Sbjct: 105 ASPEQKARWYPQAVRER----WFLGNASSENNAHVLDWRVTATPLPDGSY-EINGTKAFC 159 Query: 251 SNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEV 310 S AD VFA T G +I A ++ G+ +G++ +++ V Sbjct: 160 SGSADADRLLVFAVTSRDPNGDG----RIVAALIPSDRAGVQVNGDWDSLGMRQTDSGSV 215 Query: 311 FFDGVRVPSENVLGEVG 327 F GV V + +LG G Sbjct: 216 TFSGVVVYPDELLGTPG 232 >4JEK-A nrPDB Length = 453 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 83/356 (23%), Positives = 135/356 (37%), Gaps = 40/356 (11%) Query: 134 QGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFG 193 + L+ G L VP E GG G +V + D +G G H + I L G Sbjct: 86 EDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGHLFGYHLT-NAPMIELIG 144 Query: 194 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 253 ++ Q+E ++A +E + S + SA P+ G Y LNG+K + S Sbjct: 145 SQEQEEHLYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPTEDGGY-VLNGTKHFCSGA 201 Query: 254 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 313 +D+ VF P GA I A + G+T +G++ +++ F Sbjct: 202 KGSDLLFVFGVVQDDSPQQGA----IIAAAIPTSRAGVTPNDDWAAIGMRQTDSGSTDFH 257 Query: 314 GVRVPSENVLG------------EVGSGF-KVAMHILNNGRFGMA-------------AA 347 V+V + VLG E GS F +A I N G+A A Sbjct: 258 NVKVEPDEVLGAPNAFVLAFIQSERGSLFAPIAQLIFANVYLGIAHGALDAAREYTRTQA 317 Query: 348 LAGTMRGIIAKAVDHATNRTQFGE-KIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ 406 T GI D T R+ +GE I G +LQ V + + D+ Sbjct: 318 RPWTPAGIQQATEDPYTIRS-YGEFTIALQGADAAAREAAHLLQTVWDKGDALTPE--DR 374 Query: 407 GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFE 462 G + ++ + K + AA ++ +++G G G +R R++R + + Sbjct: 375 G--ELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFWRNVRTHSLHD 428 >3MKH-A nrPDB Length = 438 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 90/359 (25%), Positives = 147/359 (40%), Gaps = 49/359 (13%) Query: 145 QVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPK 204 Q+ GG G + A LVE + +T+ A +G I L Q ++L Sbjct: 63 QISPAHGGTGGTLIESAILVEECYSVEPSAALTIFA-TGLGLTPINL-AAGPQHAEFLAP 120 Query: 205 LASGE--TVAAFCLTEPSSGSDA-----ASIRTSAVPSPCGKYYTLNGSKLWISNGG--- 254 SGE +A+ +EP ++A +T+A G + +NG K+W +N Sbjct: 121 FLSGEGSPLASLVFSEPGGVANALEKGAPGFQTTARLE--GDEWVINGEKMWATNCAGWD 178 Query: 255 -----LADIFTVFAKTPV---TDPATGAVKEKITAFVVERG----FGGITHGPPEKKMGI 302 LA + A TP+ DP + +T ++R F + H G Sbjct: 179 FKGCDLACVVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRH---VATPGH 235 Query: 303 KASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTM-RGIIAKAVD 361 + + V + VRVP++NVL G G KVA G F +A L G M G++ A D Sbjct: 236 TSVSGPHVRYTNVRVPTKNVLCPAGQGAKVAF-----GAFDGSAVLVGAMGVGLMRAAFD 290 Query: 362 HATNRTQFGEKIHNFGLIQ--EKLARMVMLQYV------TESMAYMVSANMDQGATDFQI 413 A +F ++ + G + E+ A +L V ++ + + M+ G D+ Sbjct: 291 AA---LKFAKEDNRGGAVPLLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDA 347 Query: 414 E---AAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILR 469 A +K+F SEAA K + I +G + + +L + IF+G N +R Sbjct: 348 RRELALAAKVFCSEAAVKACTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGNVGIR 406 >1W07-A nrPDB Length = 659 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 102/441 (23%), Positives = 179/441 (40%), Gaps = 74/441 (16%) Query: 193 GTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLN-----GSK 247 GT+ Q++K+L + + + TE GS+ + T+A P + ++ SK Sbjct: 114 GTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDEFVIHTPTQTASK 173 Query: 248 LWISNGGLADIFT---VFAKTPVTDPATGAVKEKITAFVVE-------RGFGGITHGPPE 297 W GGL + T V+A+ G I F+V+ IT G Sbjct: 174 WW--PGGLGKVSTHAVVYARLITNGKDYG-----IHGFIVQLRSLEDHSPLPNITVGDIG 226 Query: 298 KKMGIKASNTAE---VFFDGVRVPSENVLGEVGSGFKVAMHILNN------------GRF 342 KMG A N+ + + FD VR+P + +L + + ++ ++ R Sbjct: 227 TKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQLVYGTMVYVRQ 286 Query: 343 GMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGL----IQEK---------LARMVML 389 + A + + + A ++ R QFG HN G+ I K LA Sbjct: 287 TIVADASNALSRAVCIATRYSAVRRQFGA--HNGGIETQVIDYKTQQNRLFPLLASAYAF 344 Query: 390 QYVTESMAYMVSANMDQ-GATDF----QIEAAIS--KIFGSEAAWKVTDECIQIMGGMGF 442 ++V E + ++ + ++ A+DF + A + K + A +EC ++ GG G+ Sbjct: 345 RFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECRKLCGGHGY 404 Query: 443 MKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLL 502 + G+ + +EG N +L+L VA + M K ++ LGS K P G + Sbjct: 405 LWCSGLPELFAVYVPACTYEGDNVVLQLQVA-RFLM---KTVAQLGSG-KVPVGTTA-YM 458 Query: 503 GEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE--AKLIKHKKGIVN 560 G A L+ R+G+ ++P++ RAL T + +K ++G Sbjct: 459 GRAAHLLQCRSGVQKA---EDWLNPDVVLEA-FEARALRMAVTCAKNLSKFENQEQGF-- 512 Query: 561 EQFLLQRLADGAIDLYAMVVV 581 Q LL L + AI ++VV Sbjct: 513 -QELLADLVEAAIAHCQLIVV 532 >5GJ7-A nrPDB Length = 398 Score = 46.2 bits (108), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 75/339 (22%), Positives = 134/339 (39%), Gaps = 34/339 (10%) Query: 134 QGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILL-- 191 + LK G VP E GG+GL + E++ D + +G H GILL Sbjct: 50 EDLKASGYVRWTVPVEYGGLGLSLEEMLMHQEVLAKGDGSTALAIGWH-----VGILLHL 104 Query: 192 -----FGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDA--ASIRTSAVPSPCGKYYTLN 244 F + + + G + + C TEP++GS + T+AV P G Y + Sbjct: 105 RETGAFPDELFRMVCESVVKEGALINS-CATEPATGSPSRGGKPETTAVKVPGG--YRIT 161 Query: 245 GSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKA 304 G K + + L+ T T AT A ++ + F+V + I +G++A Sbjct: 162 GRKTFST---LSPALTWIMVT-----ATVADEDVVGQFLVRKEDVEIVET--WDTLGMRA 211 Query: 305 SNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGR-FGMAAALAGTMRGIIAKAVDHA 363 + + ++ V VP E V+ G + +G + A G A+++A Sbjct: 212 TGSHDIVLKDVFVPEERVIVIQRPGVQAERRPDGSGWLLHIPACYLGIALAARDFALEYA 271 Query: 364 TNR--TQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATD----FQIEAAI 417 I +++KL M + ++ Y ++ D + + Q + Sbjct: 272 ATYRPNTLPHPIAEVPHVEQKLGEMELKLLAARTLLYDLARRFDAASPEERVKLQPQFGA 331 Query: 418 SKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 K + AA +V D ++++GG + +ER RD+R Sbjct: 332 VKTLATNAANQVVDLAMRVVGGRSLSRALPLERYYRDVR 370 >1IS2-A nrPDB Length = 661 Score = 37.7 bits (86), Expect = 0.014, Method: Compositional matrix adjust. Identities = 90/429 (20%), Positives = 161/429 (37%), Gaps = 69/429 (16%) Query: 114 EEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLG 173 E+ N ++ E+ + + +K++ +G+ P E+ + N+ + E + +H LG Sbjct: 49 EDYNFLTRSQRYEVAVKKSATMVKKMREYGISDPEEI--MWFKNSVHRGHPEPLDLH-LG 105 Query: 174 VGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAV 233 + + HQ+ T Q+E++ + E + TE G+ + T+A Sbjct: 106 MFLPTLLHQA----------TAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTAT 155 Query: 234 PSPCGKYYTLNGS-----KLWISNGGL---ADIFTVFAKTPVTDPATGAVKEKITAFVV- 284 P + + LN K W GGL ++ V A+ G + AFVV Sbjct: 156 YDPKTQEFILNSPTVTSIKWW--PGGLGKTSNHAIVLAQLITQGECYG-----LHAFVVP 208 Query: 285 ------ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV------GSGFKV 332 + GIT G K G + + + D R+P EN+L + G+ K Sbjct: 209 IREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKP 268 Query: 333 AMHILNNG-----RFGMAAALAGTMRGIIAKAVDHATNRTQFGEK-------IHNFGLIQ 380 + L G R + A ++ A+ ++ R Q K I +F Q Sbjct: 269 LSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQ 328 Query: 381 EKLARMVMLQYVTESMA-YM------VSANMDQG----ATDFQIEAAISKIFGSEAAWKV 429 KL ++ Y + YM ++ ++ QG + A K F + A Sbjct: 329 YKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAG 388 Query: 430 TDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDIL-----RLFVALQGCMDKGKEL 484 +EC GG G+ G+ + FEG N ++ R + + + GK + Sbjct: 389 IEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLV 448 Query: 485 SGLGSALKN 493 G+ S L + Sbjct: 449 GGMVSYLND 457 >3KN6-A nrPDB Length = 325 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 10/91 (10%) Query: 562 QFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAAL 621 + L Q D + DL+++ V+L LS P H++ L T +E +I++G + Sbjct: 179 ELLNQNGYDESCDLWSLGVILYTM---LSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSF 235 Query: 622 QSDPWQQELYRNFKSISKALVERGGVVTSNP 652 + + W +N +K L++ G++T +P Sbjct: 236 EGEAW-----KNVSQEAKDLIQ--GLLTVDP 259 >3FN9-A nrPDB Length = 692 Score = 28.9 bits (63), Expect = 7.5, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 4/107 (3%) Query: 166 IVGMHDLGVGI-TLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSD 224 + M D V + T G + KG++ F K +K+ Y A+ LT+ + Sbjct: 536 LWNMFDFAVPMWTRGGVPARNMKGLITFDRKTKKDSYFWYKANWSEEPVLYLTQRRNADR 595 Query: 225 AASIRTSAVPSPCG--KYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 V S G K Y LNG +L G D+ VF + D Sbjct: 596 EKRTTAVTVYSNIGTPKVY-LNGQELSGIRNGYTDVHYVFDNVSLAD 641 >3JVU-A nrPDB Length = 356 Score = 28.9 bits (63), Expect = 7.9, Method: Compositional matrix adjust. Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 6/90 (6%) Query: 259 FTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVP 318 F F +T + G + ++ AF RG G + P K + ++ EVF VP Sbjct: 63 FEEFLETDFSFEVPGVARFRVNAFNQNRGAGAVFRTIPSKVLTMEELGMGEVFKRVSDVP 122 Query: 319 SENVL--GEVGSG----FKVAMHILNNGRF 342 VL G GSG + LNN ++ Sbjct: 123 RGLVLVTGPTGSGKSTTLAAMLDYLNNTKY 152 >3U2O-A nrPDB Length = 395 Score = 28.5 bits (62), Expect = 9.5, Method: Compositional matrix adjust. Identities = 11/23 (47%), Positives = 16/23 (69%) Query: 270 PATGAVKEKITAFVVERGFGGIT 292 P G VK ++ A + E+GFGG+T Sbjct: 364 PVVGKVKRELEALLKEQGFGGVT 386 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3B96-A nrPDB 804 0.0 3OWA-A nrPDB 472 e-133 2Z1Q-A nrPDB 452 e-127 5OL2-C nrPDB 449 e-126 1JQI-A nrPDB 445 e-125 4N5F-A nrPDB 444 e-125 4L1F-A nrPDB 444 e-125 5LNX-A nrPDB 440 e-124 2VIG-A nrPDB 436 e-122 4U83-A nrPDB 430 e-120 4M9A-A nrPDB 423 e-118 1UKW-A nrPDB 421 e-118 6FAH-C nrPDB 416 e-116 1IVH-A nrPDB 414 e-116 4O5M-A nrPDB 412 e-115 4KTO-A nrPDB 411 e-115 1BUC-A nrPDB 406 e-113 3PFD-A nrPDB 402 e-112 2A1T-A nrPDB 402 e-112 2JIF-A nrPDB 399 e-111 3MDE-A nrPDB 399 e-111 1RX0-A nrPDB 397 e-111 2PG0-A nrPDB 392 e-109 2DVL-A nrPDB 390 e-109 4IV6-A nrPDB 386 e-107 3NF4-A nrPDB 384 e-107 3GNC-A nrPDB 384 e-107 3MPI-A nrPDB 380 e-105 4IRN-A nrPDB 378 e-105 2EBA-A nrPDB 372 e-103 2CX9-A nrPDB 371 e-103 4W9U-A nrPDB 369 e-102 1SIR-A nrPDB 364 e-100 3SF6-A nrPDB 363 e-100 6CY8-B nrPDB 355 2e-98 3SWO-A nrPDB 348 4e-96 6ES9-A nrPDB 344 6e-95 5ZW7-A nrPDB 342 3e-94 3R7K-A nrPDB 336 1e-92 5IDU-A nrPDB 332 4e-91 2IX5-A nrPDB 330 2e-90 2WBI-A nrPDB 325 4e-89 5JSC-A nrPDB 311 5e-85 3P4T-A nrPDB 309 3e-84 1W07-A nrPDB 304 7e-83 5AHS-A nrPDB 304 8e-83 4HR3-A nrPDB 295 4e-80 2FON-A nrPDB 286 3e-77 5Y9D-A nrPDB 268 4e-72 4RM7-A nrPDB 264 7e-71 5YS9-A nrPDB 261 9e-70 4ZYJ-A nrPDB 259 3e-69 4X28-A nrPDB 259 3e-69 1R2J-A nrPDB 249 3e-66 3M9V-A nrPDB 240 2e-63 4Y9J-A nrPDB 239 4e-63 5GJ7-A nrPDB 236 2e-62 3MKH-A nrPDB 231 1e-60 2C12-A nrPDB 227 1e-59 3U33-A nrPDB 223 3e-58 3MXL-A nrPDB 219 3e-57 5EZ3-A nrPDB 213 2e-55 4JEK-A nrPDB 199 4e-51 4XVX-A nrPDB 198 6e-51 5XDD-A nrPDB 196 3e-50 Sequences not found previously or not previously below threshold: 1IS2-A nrPDB 169 4e-42 5K3G-A nrPDB 156 4e-38 5K3J-A nrPDB 154 2e-37 4X28-D nrPDB 142 5e-34 2RFQ-A nrPDB 99 4e-21 5LVW-A nrPDB 97 3e-20 3AFF-A nrPDB 95 1e-19 2JBS-A nrPDB 86 7e-17 2OR0-A nrPDB 74 3e-13 3HWC-A nrPDB 43 4e-04 1U8V-A nrPDB 38 0.012 2YYI-A nrPDB 36 0.062 1AKL-A nrPDB 34 0.22 5LC3-A nrPDB 32 1.3 4C9G-A nrPDB 31 1.3 6FPC-A nrPDB 31 1.9 4S1V-D nrPDB 30 2.8 5Y9S-A nrPDB 30 3.6 1V9S-A nrPDB 29 9.0 2DUB-A nrPDB 29 9.2 >3B96-A nrPDB Length = 587 Score = 804 bits (2077), Expect = 0.0, Method: Composition-based stats. Identities = 587/587 (100%), Positives = 587/587 (100%) Query: 69 ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMV 128 ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMV Sbjct: 1 ESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMV 60 Query: 129 EETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKG 188 EETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKG Sbjct: 61 EETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKG 120 Query: 189 ILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL 248 ILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL Sbjct: 121 ILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL 180 Query: 249 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA 308 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA Sbjct: 181 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA 240 Query: 309 EVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ 368 EVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ Sbjct: 241 EVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQ 300 Query: 369 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK 428 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK Sbjct: 301 FGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWK 360 Query: 429 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG 488 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG Sbjct: 361 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG 420 Query: 489 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE 548 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE Sbjct: 421 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE 480 Query: 549 AKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCI 608 AKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCI Sbjct: 481 AKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCI 540 Query: 609 EAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF 655 EAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF Sbjct: 541 EAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF 587 >3OWA-A nrPDB Length = 597 Score = 472 bits (1214), Expect = e-133, Method: Composition-based stats. Identities = 191/610 (31%), Positives = 289/610 (47%), Gaps = 65/610 (10%) Query: 57 SDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKE----LVEPVSRF 112 S+A+ + + SF V ++T DQVF P + E K +V V Sbjct: 1 SNAMEKTVGNAVKGGSFLVD----EITIDQVFT-PEDFSSEHKMIAKTTEDFIVNEVLPE 55 Query: 113 FEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDL 172 E + + ++ +++E ELG G VP E GG+GL A + E Sbjct: 56 LEYLEQHEFDRSVRLLKEA-----GELGLLGADVPEEYGGIGLDKVSSALIAEKFSRA-G 109 Query: 173 GVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSA 232 G IT GAH IG I+LFG + QK+KYLP LA+GE +AA+ LTEP SGSDA +T+A Sbjct: 110 GFAITHGAHVGIGSLPIVLFGNEEQKKKYLPLLATGEKLAAYALTEPGSGSDALGAKTTA 169 Query: 233 VPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGIT 292 + G +Y LNG K WI+N AD+F V+AK E +AF+VE+ + G++ Sbjct: 170 RLNAEGTHYVLNGEKQWITNSAFADVFIVYAKIDG---------EHFSAFIVEKDYAGVS 220 Query: 293 HGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTM 352 P EKKMGIK S+T + + VP EN+LGE+G G +A +ILN GR+ + G+ Sbjct: 221 TSPEEKKMGIKCSSTRTLILEDALVPKENLLGEIGKGHIIAFNILNIGRYKLGVGTVGSA 280 Query: 353 RGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGAT--- 409 + + + +A R QF + I F LIQEKLA M Y ES Y + + Sbjct: 281 KRAVEISAQYANQRQQFKQPIARFPLIQEKLANMAAKTYAAESSVYRTVGLFESRMSTLS 340 Query: 410 ---------------DFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRD 454 ++ IE +++K+FGSE DE +QI GG GFM E +ER+ RD Sbjct: 341 EEEVKDGKAVAASIAEYAIECSLNKVFGSEVLDYTVDEGVQIHGGYGFMAEYEIERMYRD 400 Query: 455 LRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAG 514 RI RIFEGTN+I RL V K L L + ++L+ Sbjct: 401 SRINRIFEGTNEINRLIVPGTFLRKAMKG---------------ELPLLQKAQKLQEELM 445 Query: 515 LGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAID 574 + + L+ L A + V K+ K + EQ +L +AD + Sbjct: 446 MMMPEEVGD---EPLALQKYLVNNAKKIGLMVAGLAAQKYGKALDKEQEILVNIADIVSN 502 Query: 575 LYAMVVVLSRASRSL-SEGHPTAQHEKMLCDTWCIEAAARI----REGMAALQSDPWQQE 629 LYAM + R +++ + G + + + + +C EA I +E + A+++ + Sbjct: 503 LYAMESAVLRTEKAIKTTGLEKNKQKVLYTEVFCQEAFNEIEAHAKETLIAVENGDMLRM 562 Query: 630 LYRNFKSISK 639 + + + +++ Sbjct: 563 MLSSLRKLTR 572 >2Z1Q-A nrPDB Length = 577 Score = 452 bits (1163), Expect = e-127, Method: Composition-based stats. Identities = 194/523 (37%), Positives = 266/523 (50%), Gaps = 54/523 (10%) Query: 82 LTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGA 141 L + P +E + + V R + + ++ LE + + ELG Sbjct: 16 LEVPERVYTPEDFDESVKEIARTTRTFVEREVLPLLERMEHGELE-LNVPLMRKAGELGL 74 Query: 142 FGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKY 201 + VP E GG+ L + E + G +T GAH SIG ++ FGT+ QK KY Sbjct: 75 LAIDVPEEYGGLDLPKVISTVVAEELS-GSGGFSVTYGAHTSIGTLPLVYFGTEEQKRKY 133 Query: 202 LPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTV 261 LPKLASGE +AA+CLTEP SGSDA + +T A S GK+Y LNG K WISN G A +FTV Sbjct: 134 LPKLASGEWIAAYCLTEPGSGSDALAAKTRATLSEDGKHYILNGVKQWISNAGFAHLFTV 193 Query: 262 FAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSEN 321 FAK E TAF+VER G++ GP EKKMGIKAS+T +V + V+VP EN Sbjct: 194 FAKVDG---------EHFTAFLVERDTPGLSFGPEEKKMGIKASSTRQVILEDVKVPVEN 244 Query: 322 VLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQE 381 VLGE+G G K+A ++LN GR+ + A G + + + +AT R QFG I FGLIQ+ Sbjct: 245 VLGEIGKGHKIAFNVLNVGRYKLGAGAVGGAKRALELSAQYATQRVQFGRPIGRFGLIQQ 304 Query: 382 KLARMVMLQYVTESMAYMVSANMDQ-------------GATDFQIEAAISKIFGSEAAWK 428 KL M Y ES Y +D+ G ++ +EA+I K+ GSE Sbjct: 305 KLGEMASRIYAAESAVYRTVGLIDEALLGKKGPEAVMAGIEEYAVEASIIKVLGSEVLDY 364 Query: 429 VTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLG 488 V DE +QI GG G+ +E +ER RD RI RIFEGTN+I RL + K Sbjct: 365 VVDEGVQIHGGYGYSQEYPIERAYRDARINRIFEGTNEINRLLIPGMLLRRALKG----- 419 Query: 489 SALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELA---VRALEQFAT 545 L L +A ++L++ L+ P +L V+ L++ A Sbjct: 420 ----------QLPLMQAAQRLQKE-----------LLEPSFEEPEDLELHQVQNLKKLAL 458 Query: 546 VVEAKLI-KHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASR 587 +V + K+ +G+ EQ +L +AD ID YA L RA R Sbjct: 459 MVAGLAVQKYGQGVEEEQEVLGAVADILIDAYAAESALLRARR 501 >5OL2-C nrPDB Length = 378 Score = 449 bits (1156), Expect = e-126, Method: Composition-based stats. Identities = 141/385 (36%), Positives = 215/385 (55%), Gaps = 9/385 (2%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGG 152 LN ++ Q LKEL + E + D E T + + + G G+ P E GG Sbjct: 2 DLNSKKYQMLKELYVSFA-ENEVKPLATELDEEERFPYETVEKMAKAGMMGIPYPKEYGG 60 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVA 212 G Y VE + G+ L AH S+G I +G + QK+K+L LASGE + Sbjct: 61 EGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGNEEQKQKFLRPLASGEKLG 120 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 AF LTEP++G+DA+ +T+AV G Y LNGSK++I+N DI+ V A T + Sbjct: 121 AFGLTEPNAGTDASGQQTTAVLD--GDEYILNGSKIFITNAIAGDIYVVMAMTDKSKGNK 178 Query: 273 GAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKV 332 G I+AF+VE+G G + G EKKMGI+ S T+E+ F+ R+P EN+LG+ G GFK+ Sbjct: 179 G-----ISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRIPKENLLGKEGQGFKI 233 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYV 392 AM L+ GR G+AA G +G + + V + R QFG + F Q +LA M + Sbjct: 234 AMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSKFQNTQFQLADMEVKVQA 293 Query: 393 TESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452 + Y + N D G + +EAA++K+F +E A +VT + +Q+ GG G+ ++ VER++ Sbjct: 294 ARHLVYQAAINKDLGK-PYGVEAAMAKLFAAETAMEVTTKAVQLHGGYGYTRDYPVERMM 352 Query: 453 RDLRIFRIFEGTNDILRLFVALQGC 477 RD +I I+EGT+++ R+ ++ + Sbjct: 353 RDAKITEIYEGTSEVQRMVISGKLL 377 >1JQI-A nrPDB Length = 388 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 132/391 (33%), Positives = 202/391 (51%), Gaps = 11/391 (2%) Query: 90 YPSVLNEEQTQFLKEL-VEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPS 148 Y SV E Q L++ + + V A+ D + + + + ELG + VP Sbjct: 5 YQSVELPETHQMLRQTCRDFAEKEL--VPIAAQLDKEHLFPTSQVKKMGELGLLAMDVPE 62 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 208 EL G GL Y+ +E + G+ + + S+ IL FG+ QK++++ +G Sbjct: 63 ELSGAGLDYLAYSIALEEISRGCASTGVIMSVNNSLYLGPILKFGSSQQKQQWITPFTNG 122 Query: 209 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 268 + + F L+EP +GSDA + T+A G + LNG+K WI+N A VFA T + Sbjct: 123 DKIGCFALSEPGNGSDAGAASTTAREE--GDSWVLNGTKAWITNSWEASATVVFASTDRS 180 Query: 269 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 328 + I+AF+V G+T G E K+GI+AS+TA + F+ R+P EN+LGE G Sbjct: 181 -----RQNKGISAFLVPMPTPGLTLGKKEDKLGIRASSTANLIFEDCRIPKENLLGEPGM 235 Query: 329 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 388 GFK+AM L+ GR G+A+ G + + AV +A NR FG + IQ KLA M + Sbjct: 236 GFKIAMQTLDMGRIGIASQALGIAQASLDCAVKYAENRHAFGAPLTKLQNIQFKLADMAL 295 Query: 389 LQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV 448 + + + D F E+A++K+ SEAA ++ + IQI+GGMG++ E Sbjct: 296 ALESARLLTWRAAMLKDN-KKPFTKESAMAKLAASEAATAISHQAIQILGGMGYVTEMPA 354 Query: 449 ERVLRDLRIFRIFEGTNDILRLFVALQGCMD 479 ER RD RI I+EGT++I RL +A Sbjct: 355 ERYYRDARITEIYEGTSEIQRLVIAGHLLRS 385 >4N5F-A nrPDB Length = 385 Score = 444 bits (1142), Expect = e-125, Method: Composition-based stats. Identities = 141/384 (36%), Positives = 206/384 (53%), Gaps = 10/384 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 ++E T+ + + + F E+ P A+ D + + L ELG G+ VP ELG Sbjct: 9 MDELYTEDQRMIRDAARAFATEMLAPNAAQWDHDAHLPDAIVAQLGELGLLGMIVPQELG 68 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G YA +E V D + H S+G IL FGT AQK+++L +A+G + Sbjct: 69 GSYTDYVAYALAMEEVAAGDAACATMMSVHNSVGCGPILGFGTPAQKDRWLADMAAGRVI 128 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 AFCLTEP +GS+A ++RT A + LNG+K +++NG A + VFA +TDP Sbjct: 129 GAFCLTEPHAGSEANNLRTRAELRD--GQWVLNGAKQFVTNGQRAGVAIVFA---MTDPE 183 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 G K I+AF+V G G PEKKMGI+AS+T + F+ +P +N+LG G G K Sbjct: 184 AG--KRGISAFLVPTDTPGFIVGKPEKKMGIRASDTCPITFENCAIPEDNLLGNRGEGLK 241 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 +A+ L GR G+AA G R KA +A R QFG+ I IQ+KLA M + Sbjct: 242 IALSNLEGGRIGIAAQALGIARAAFDKARRYAGERVQFGKPIAEHQAIQQKLADMAVQIN 301 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 + + + G EA+ +K+F SE A +V + IQI GG G++ + VER Sbjct: 302 AARLLVHHAAKLRTAG-LPCLSEASQAKLFASEMAERVCSDAIQIHGGYGYLVDYEVERH 360 Query: 452 LRDLRIFRIFEGTNDILRLFVALQ 475 RD RI +I+EGT+++ R+ +A Q Sbjct: 361 YRDARITQIYEGTSEVQRMVIARQ 384 >4L1F-A nrPDB Length = 383 Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 142/391 (36%), Positives = 212/391 (54%), Gaps = 10/391 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 ++ T+ + + + + F E+ P + D + + + E G G+ P E G Sbjct: 1 MDFNLTEDQQMIKDMAAEFAEKFLAPTVEERDKAHIWDRKLIDKMGEAGFCGICFPEEYG 60 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G+GL Y VE + D G GITL A+ S+ I +FGT+ QK+KYL +A G V Sbjct: 61 GMGLDVLSYILAVEELSKVDDGTGITLSANVSLCATPIYMFGTEEQKQKYLAPIAEGTHV 120 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 AF LTEPS+G+DA++ +T+AV G Y LNGSK++I+NG AD + VFA T + Sbjct: 121 GAFGLTEPSAGTDASAQQTTAVLK--GDKYILNGSKIFITNGKEADTYVVFAMTDKSQG- 177 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 I+AF++E+G G G E KMG S TAE+ F+ VP EN+LG+ G GFK Sbjct: 178 ----VHGISAFILEKGMPGFRFGKIEDKMGGHTSITAELIFEDCEVPKENLLGKEGEGFK 233 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 +AM L+ GR G+AA G G +A AV ++ R QFG I F +Q +A M Sbjct: 234 IAMETLDGGRIGVAAQALGIAEGALAAAVKYSKEREQFGRSISKFQALQFMMADMATKIE 293 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 + Y + ++G + AA++K F S+ A +VT + +QI GG G+ + ER Sbjct: 294 AARYLVYHAAMLKNEGK-PYSEAAAMAKCFASDVAMEVTTDAVQIFGGYGYTVDYPAERY 352 Query: 452 LRDLRIFRIFEGTNDILRLFVALQGCMDKGK 482 +R+ +I +I+EGTN ++R+ + DK K Sbjct: 353 MRNAKITQIYEGTNQVMRIVTSRALLRDKKK 383 >5LNX-A nrPDB Length = 379 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 141/384 (36%), Positives = 203/384 (52%), Gaps = 10/384 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 + +EQ K + + + + + + + + G G+ VP + GG Sbjct: 3 VTQEQVMMRKMVRDFARKEIA--PAAEIMEKTDEFPFQLIKKMGKHGLMGIPVPEQYGGA 60 Query: 154 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 G Y + + VG+ L H S+G IL FG + QK KY+P LASG+ + A Sbjct: 61 GADVVSYILAIHEISRISAAVGVILSVHTSVGTNPILYFGNEEQKMKYIPNLASGDHLGA 120 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 F LTEP SGSDA S+RT+A+ Y LNGSK++I+NGG ADI+ FA T Sbjct: 121 FALTEPHSGSDAGSLRTTAIKKN--GKYLLNGSKIFITNGGAADIYITFALTAPDQG--- 175 Query: 274 AVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVA 333 + I+AF+VE+ G T G E+K+G+ SNT E+ FD VP N+LG+ G GF +A Sbjct: 176 --RHGISAFIVEKNTPGFTVGKKERKLGLYGSNTTELIFDNAEVPEANLLGKEGDGFHIA 233 Query: 334 MHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVT 393 M LN GR G+AA G + AVD+A R QFG I I KLA M Sbjct: 234 MANLNVGRIGIAAQALGIAEAALEHAVDYAKQRVQFGRPIAANQGISFKLADMATRAEAA 293 Query: 394 ESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLR 453 + Y + ++G + EA+++K F S+AA K + +QI GG G+MK+ VER+LR Sbjct: 294 RHLVYHAADLHNRG-LNCGKEASMAKQFASDAAVKAALDAVQIYGGYGYMKDYPVERLLR 352 Query: 454 DLRIFRIFEGTNDILRLFVALQGC 477 D ++ +I+EGTN+I RL ++ Sbjct: 353 DAKVTQIYEGTNEIQRLIISKYLL 376 >2VIG-A nrPDB Length = 391 Score = 436 bits (1122), Expect = e-122, Method: Composition-based stats. Identities = 129/386 (33%), Positives = 196/386 (50%), Gaps = 10/386 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 L E L+ + + A+ D + + + LG + VP ELGG Sbjct: 6 LPETHQMLLQTCRDFAEKEL--FPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGA 63 Query: 154 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 GL YA +E + G+ + + S+ IL FG+K QK+ ++ SG+ + Sbjct: 64 GLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQAWVTPFTSGDKIGC 123 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 F L+EP +GSDA + T+A G + LNG+K WI+N A VFA T Sbjct: 124 FALSEPGNGSDAGAASTTARAE--GDSWVLNGTKAWITNAWEASAAVVFASTD-----RA 176 Query: 274 AVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVA 333 + I+AF+V G+T G E K+GI+ S+TA + F+ R+P +++LGE G GFK+A Sbjct: 177 LQNKSISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIA 236 Query: 334 MHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVT 393 M L+ GR G+A+ G + + AV++A NR FG + +IQ KLA M + Sbjct: 237 MQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESA 296 Query: 394 ESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLR 453 + + + D F EAA++K+ SEAA ++ + IQI+GGMG++ E ER R Sbjct: 297 RLLTWRAAMLKDN-KKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYR 355 Query: 454 DLRIFRIFEGTNDILRLFVALQGCMD 479 D RI I+EGT++I RL +A Sbjct: 356 DARITEIYEGTSEIQRLVIAGHLLRS 381 >4U83-A nrPDB Length = 382 Score = 430 bits (1105), Expect = e-120, Method: Composition-based stats. Identities = 132/379 (34%), Positives = 194/379 (51%), Gaps = 10/379 (2%) Query: 98 QTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGL 155 T +++ E F +E P A D + LG G+ P E GG L Sbjct: 10 LTDTQEQIREAARDFAQERLAPGAAARDREHAFPRAELTEMGALGFLGMLAPEEWGGSDL 69 Query: 156 CNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFC 215 YA +E + D + H S+G IL FGT+ QK ++LPK+A GE + F Sbjct: 70 DMVAYALALEEIAAGDGACSTIVSVHSSVGCMPILRFGTEDQKRRFLPKMACGEWIGGFA 129 Query: 216 LTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAV 275 LTEP +GSDA++++T A G +Y ++GSK +I++G ++ VFA T DPA G Sbjct: 130 LTEPQAGSDASALKTRARLD--GDHYVIDGSKQFITSGKNGNVVIVFAVT---DPAAG-- 182 Query: 276 KEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMH 335 K+ I+AF+V G E K+G +S+T + F +RVP EN LG G G+K+A+ Sbjct: 183 KKGISAFIVPTDTPGYEVMSVEHKLGQHSSDTCALGFTNMRVPVENRLGAEGEGYKIALA 242 Query: 336 ILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTES 395 L GR G+AA G R A D+A R FG+ I + +LA M Sbjct: 243 NLEGGRIGIAAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQ 302 Query: 396 MAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDL 455 M +A + G EA+++K+ SE A +V IQI GG G++ + VER+ RD+ Sbjct: 303 MVLHAAALREAGK-PCLTEASMAKLVASEMAEQVCSAAIQIHGGYGYLADYPVERIYRDV 361 Query: 456 RIFRIFEGTNDILRLFVAL 474 R+ +I+EGT+D+ RL +A Sbjct: 362 RVCQIYEGTSDVQRLVIAR 380 >4M9A-A nrPDB Length = 385 Score = 423 bits (1087), Expect = e-118, Method: Composition-based stats. Identities = 138/384 (35%), Positives = 203/384 (52%), Gaps = 10/384 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 +++ T+ + +++ F EV P A+ D + + + ELG G+ VP++ G Sbjct: 9 MDDLYTEDQRMILDAARAFCAEVLAPNAAQWDRESHLPDEVVAQMGELGFLGMIVPADWG 68 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G YA +E + + H S+G +L +GT QKE++L LASG+TV Sbjct: 69 GSYTDYVAYALALEEIAAGCASCATLVSVHNSVGCGPVLNYGTTEQKERWLRDLASGKTV 128 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 AF LTEP +GS+A ++RT A + LNGSK +++NG A + VFA +TDP Sbjct: 129 GAFSLTEPHAGSEAHNLRTRAELRD--GKWILNGSKQFVTNGARAGLAIVFA---MTDPD 183 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 G K ++AFVV G G PEKKMGI+AS+T + + +P EN+LG+ G G K Sbjct: 184 EG--KRGLSAFVVPTDTPGFIVGKPEKKMGIRASDTCPITLENCAIPQENLLGKRGEGLK 241 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 +A+ L GR G+AA G R +A +A R QFG+ I I EKLA M Sbjct: 242 IALSNLEGGRIGIAAQATGIARAAFDRARRYARERVQFGKPIAEHQAIAEKLANMATQIN 301 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 + + + G EA+ +K+F SE A V + IQI GG GF+ + VER Sbjct: 302 AARLLTHHAARLRTAG-LPCLSEASQAKLFASEMAEAVCSDAIQIHGGYGFLVDYEVERH 360 Query: 452 LRDLRIFRIFEGTNDILRLFVALQ 475 RD RI +I+EGT+++ R+ +A Q Sbjct: 361 YRDARITQIYEGTSEVQRMVIARQ 384 >1UKW-A nrPDB Length = 379 Score = 421 bits (1083), Expect = e-118, Method: Composition-based stats. Identities = 142/386 (36%), Positives = 207/386 (53%), Gaps = 11/386 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 ++ T+ ++L RF +EV P + D E V + L E+G +P E G Sbjct: 1 IDFSLTEEQRQLQALARRFAKEVILPVAQEYDEKEEVPWPVIEKLHEVGLLNAIIPEEYG 60 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G+GL + E + +G+ T+ +G +LL GT+ QKE++L L + Sbjct: 61 GMGLKMLDEVIVGEELAYACMGI-YTIPMASDLGITPVLLAGTEEQKERFLRPLTEKPAL 119 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 AAF L+EP +GSDAA+++T A+ G +Y LNG+K+WISNGG A+ VFA Sbjct: 120 AAFALSEPGNGSDAAALKTRAIRQ--GDHYVLNGTKMWISNGGEAEWVVVFATV-----N 172 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 + + A VVERG G KMG +AS T E+ F+ V+VP EN LGE G GFK Sbjct: 173 PELRHKGVVALVVERGTPGFKAIKIHGKMGQRASGTYELVFEDVKVPVENRLGEEGEGFK 232 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 +AM LN R +AA G R + +A +A R FGE I NF IQ KL M++ Sbjct: 233 IAMQTLNKTRIPVAAGSVGVARRALDEARKYAKEREAFGEPIANFQAIQFKLVDMLIGIE 292 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 Y + DQG +AI+K + SE A++ ++ IQI GG G+++E VE++ Sbjct: 293 TARMYTYYAAWLADQGLPHAHA-SAIAKAYASEIAFEAANQAIQIHGGYGYVREFPVEKL 351 Query: 452 LRDLRIFRIFEGTNDILRLFVALQGC 477 LRD+++ +I+EGTN+I RL +A Sbjct: 352 LRDVKLNQIYEGTNEIQRLIIARHIL 377 >6FAH-C nrPDB Length = 379 Score = 416 bits (1070), Expect = e-116, Method: Composition-based stats. Identities = 120/384 (31%), Positives = 198/384 (51%), Gaps = 9/384 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 +E+ K + + ++ E + + + G FG+++P LGG Sbjct: 3 FSEQNKMIRKLARDFAEKELTTEILDEVEESGE-FPQEILDKMAKFGFFGIKIPKSLGGS 61 Query: 154 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 G + Y +E + L + S+ +LL GT+ Q EKYL + +G+ A Sbjct: 62 GGDHMSYVICMEEFARVSGVASVYLSSPNSLAGGPLLLSGTEEQIEKYLKPIITGKKKLA 121 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 F LTEP +GSDA + T+AV G YY LNG K +I+ L D ++AKT ++ G Sbjct: 122 FALTEPGAGSDAGGMSTTAV--DMGDYYLLNGRKTFITMAPLCDDAVIYAKTDMSKGTRG 179 Query: 274 AVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVA 333 I+AF+V+ G++ G E KMG+ T+++ + V+VP EN LGEV GF A Sbjct: 180 -----ISAFIVDLKSEGVSMGKNEHKMGLIGCATSDIIMEDVKVPKENRLGEVNKGFSNA 234 Query: 334 MHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVT 393 M L+ GR G+A+ G +G + +A+ +A R QFG++I +F I +A M Sbjct: 235 MKTLDVGRLGVASQSIGVAQGALDEAIKYAKERKQFGKRIADFQAIAFMIADMATKLEAA 294 Query: 394 ESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLR 453 + + Y ++ MD + EA+++K + SE ++ + +QI GG G++KE VER+ R Sbjct: 295 KLLVYNAASLMDN-KKNATKEASMAKFYASEICNEICAKAVQIHGGYGYIKEYKVERMYR 353 Query: 454 DLRIFRIFEGTNDILRLFVALQGC 477 D R+F I+EGT+ + ++ ++ Sbjct: 354 DCRVFTIYEGTSQVQQMVISGMLL 377 >1IVH-A nrPDB Length = 394 Score = 414 bits (1065), Expect = e-116, Method: Composition-based stats. Identities = 122/387 (31%), Positives = 197/387 (50%), Gaps = 6/387 (1%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGG 152 L+EEQ Q + + + + W+ L LG G+ P + GG Sbjct: 12 GLSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLREFWKQLGNLGVLGITAPVQYGG 71 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVA 212 GL ++ ++E + VG++ GAH ++ ++ G +AQKEKYLPKL SGE + Sbjct: 72 SGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCINQLVRNGNEAQKEKYLPKLISGEYIG 131 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 A ++EP++GSD S++ A G +Y LNG+K WI+NG AD+ V+AKT D A Sbjct: 132 ALAMSEPNAGSDVVSMKLKAEKK--GNHYILNGNKFWITNGPDADVLIVYAKT---DLAA 186 Query: 273 GAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKV 332 ITAF+VE+G G + K+G++ SNT E+ F+ ++P+ N+LG G V Sbjct: 187 VPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELIFEDCKIPAANILGHENKGVYV 246 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYV 392 M L+ R +A G M+ ++ + + R FG+KI +F L+Q K+A M Sbjct: 247 LMSGLDLERLVLAGGPLGLMQAVLDHTIPYLHVREAFGQKIGHFQLMQGKMADMYTRLMA 306 Query: 393 TESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452 Y V+ D+G + A + ++ +E A +V + IQ GG G++ + + R L Sbjct: 307 CRQYVYNVAKACDEGHCTAKDCAGVI-LYSAECATQVALDGIQCFGGNGYINDFPMGRFL 365 Query: 453 RDLRIFRIFEGTNDILRLFVALQGCMD 479 RD +++ I GT+++ RL + D Sbjct: 366 RDAKLYEIGAGTSEVRRLVIGRAFNAD 392 >4O5M-A nrPDB Length = 390 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 126/386 (32%), Positives = 203/386 (52%), Gaps = 10/386 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 +N + ++ L + V RF E P A+ D W+ ELG G+ P + G Sbjct: 9 MNFGLGEEIEALRDTVRRFAESRIAPLAAETDRNNQFPMHLWREFGELGVLGITAPEDYG 68 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G G+ + +E + +G++ GAH ++ I G+ Q+ KYLPKL SGE V Sbjct: 69 GAGMGYLAHCIAMEEISRASASIGLSYGAHSNLCVNQITRNGSPEQRAKYLPKLISGEHV 128 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 A ++EP +GSD S++ +A G Y LNG+K+WI+NG AD+ V+AKT ++ Sbjct: 129 GALAMSEPGAGSDVVSMKLAAEKR--GDRYVLNGNKMWITNGPDADVLVVYAKTDLS--- 183 Query: 272 TGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK 331 A I+AF++E+GF G + K+G++ SNT E+ F+ VP+EN+LG G G Sbjct: 184 --AGPRGISAFIIEKGFKGFSTAQKLDKLGMRGSNTCELVFEDCEVPAENLLGTEGKGVN 241 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 V M L+ R +A G M + V + R QF + I F L+Q KLA M + Sbjct: 242 VLMSGLDYERVVLAGGPLGIMAACLDVVVPYVHERKQFDQPIGEFQLMQCKLADMYVTFN 301 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 + + Y V+A D+G T + +AA ++ +E A ++ + IQ +GG G++ + R+ Sbjct: 302 ASRAYVYAVAAACDRGETT-RKDAAGCILYSAENATQMALQAIQSLGGNGYINDYPTGRL 360 Query: 452 LRDLRIFRIFEGTNDILRLFVALQGC 477 LRD +++ I GT++I R+ + + Sbjct: 361 LRDAKLYEIGAGTSEIRRMLIGRELF 386 >4KTO-A nrPDB Length = 410 Score = 411 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 141/394 (35%), Positives = 204/394 (51%), Gaps = 10/394 (2%) Query: 86 QVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDAL--EMVEETTWQGLKELGAFG 143 Q + + LN + + L V RF E P +DA + W+ + ELG G Sbjct: 21 QSMMFEAGLNFALGEEIDALRASVRRFASERIAPLADDADRSNAFPMSLWREMGELGLLG 80 Query: 144 LQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLP 203 + GG GL + +E + VG++ GAH ++ I G AQK +YLP Sbjct: 81 ITADEAHGGAGLGYLAHCVAMEEISRASASVGLSYGAHSNLCVNQINRNGKPAQKSRYLP 140 Query: 204 KLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFA 263 KL SGE V A ++EP +GSD S++ A G Y LNGSK+WI+NG AD+ V+A Sbjct: 141 KLISGEHVGALAMSEPGAGSDVVSMKLKA--DKRGDRYVLNGSKMWITNGPDADVLVVYA 198 Query: 264 KTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL 323 KT DPA G ITAF+VE+ F G + G K+G++ SNT+E+ F VP ENVL Sbjct: 199 KT---DPAAG--PRGITAFLVEKAFPGFSAGQKLDKLGMRGSNTSELIFTDCEVPEENVL 253 Query: 324 GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKL 383 G VG G KV M L+ R ++A G M + V + R QFG+ I F L+Q KL Sbjct: 254 GGVGEGVKVLMSGLDYERVVLSAGPLGIMAACLDVVVPYLHERKQFGQPIGEFQLMQGKL 313 Query: 384 ARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFM 443 A M + + Y V+A D+G T + +AA ++ +E A + E IQ +GG G+ Sbjct: 314 ADMYVTMNAARAYVYAVAAACDRGET-ARKDAAGCILYAAEKATAMALEAIQALGGNGYT 372 Query: 444 KEPGVERVLRDLRIFRIFEGTNDILRLFVALQGC 477 + R+LRD +++ I GT++I R+ + + Sbjct: 373 NDYPAGRLLRDAKLYEIGAGTSEIRRMLIGRELF 406 >1BUC-A nrPDB Length = 383 Score = 406 bits (1044), Expect = e-113, Method: Composition-based stats. Identities = 147/390 (37%), Positives = 211/390 (54%), Gaps = 12/390 (3%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPA--KNDALEMVEETTWQGLKELGAFGLQVPSELG 151 ++ T ++ ++ F E+ P + D + ++ L LG G + G Sbjct: 1 MDFNLTDIQQDFLKLAHDFGEKKLAPTVTERDHKGIYDKELIDELLSLGITGAYFEEKYG 60 Query: 152 GVGLCN---TQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 208 G G Y VE + +D GV ITL A S+ I FGT+AQKEK+L L G Sbjct: 61 GSGDDGGDVLSYILAVEELAKYDAGVAITLSATVSLCANPIWQFGTEAQKEKFLVPLVEG 120 Query: 209 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 268 + AF LTEP++G+DA+ +T A + G YTLNGSK++I+NGG ADI+ VFA T + Sbjct: 121 TKLGAFGLTEPNAGTDASGQQTIATKNDDG-TYTLNGSKIFITNGGAADIYIVFAMTDKS 179 Query: 269 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 328 G ITAF++E G G T+G E KMGI S T E+ F V+VP+EN+LGE G Sbjct: 180 KGNHG-----ITAFILEDGTPGFTYGKKEDKMGIHTSQTMELVFQDVKVPAENMLGEEGK 234 Query: 329 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 388 GFK+AM L+ GR G+AA G +A AV+++ R QFG+ + F I KLA M M Sbjct: 235 GFKIAMMTLDGGRIGVAAQALGIAEAALADAVEYSKQRVQFGKPLCKFQSISFKLADMKM 294 Query: 389 LQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV 448 ++ Y + +G F ++AAI+K S+ A +VT E +QI GG G+ +E V Sbjct: 295 QIEAARNLVYKAACKKQEGK-PFTVDAAIAKRVASDVAMRVTTEAVQIFGGYGYSEEYPV 353 Query: 449 ERVLRDLRIFRIFEGTNDILRLFVALQGCM 478 R +RD +I +I+EGTN++ + Sbjct: 354 ARHMRDAKITQIYEGTNEVQLMVTGGALLR 383 >3PFD-A nrPDB Length = 393 Score = 402 bits (1034), Expect = e-112, Method: Composition-based stats. Identities = 132/385 (34%), Positives = 204/385 (52%), Gaps = 10/385 (2%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 L EE + + + A+ D E L G + VP E GG Sbjct: 19 LPEEHIALREAIRALAEKEIA--PYAAEVDEKARFPEEALAALNSSGFSAIHVPEEYGGQ 76 Query: 154 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 G + ++E V D + + A +G G++L G++ K++ LP +ASGE +A+ Sbjct: 77 GADSVATCIVIEEVARVDCSASL-IPAVNKLGTMGLILRGSEELKKQVLPAVASGEAMAS 135 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 + L+E +GSDAAS+RT AV G + LNGSK WI+NGG + +TV A T DP G Sbjct: 136 YALSEREAGSDAASMRTRAVAD--GDDWILNGSKCWITNGGKSTWYTVMAVT---DPDKG 190 Query: 274 AVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVA 333 A I+AF+V + G T GP E+K+GIK S T E++F+ R+P + ++GE G+GFK A Sbjct: 191 A--NGISAFMVHKDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTA 248 Query: 334 MHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVT 393 + L++ R + A G +G + A+ + R QFG + + +Q LA M M Sbjct: 249 LATLDHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMAMKIEAA 308 Query: 394 ESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLR 453 M Y +A ++G D +A SK F S+ A +VT + +Q+ GG G+ ++ VER++R Sbjct: 309 RLMVYSAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLFGGYGYTQDFPVERMMR 368 Query: 454 DLRIFRIFEGTNDILRLFVALQGCM 478 D +I +I+EGTN I R+ ++ Sbjct: 369 DAKITQIYEGTNQIQRVVMSRALLR 393 >2A1T-A nrPDB Length = 421 Score = 402 bits (1032), Expect = e-112, Method: Composition-based stats. Identities = 129/408 (31%), Positives = 199/408 (48%), Gaps = 10/408 (2%) Query: 78 FKGQLTTDQVFPYPSV-LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQ 134 ++ Q T P + + E T+ KE +F E P A+ D + Sbjct: 20 WRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIR 79 Query: 135 GLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGT 194 ELG +P GG+GL + E + GV + S+G I++ G Sbjct: 80 RAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQTAIEG-NSLGQMPIIIAGN 138 Query: 195 KAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGG 254 QK+KYL ++ + A+C+TEP +GSD A I+T A G Y +NG K+WI+NGG Sbjct: 139 DQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMWITNGG 196 Query: 255 LADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDG 314 A+ + + A++ A + T F+VE GI G E MG + S+T + F+ Sbjct: 197 KANWYFLLARSDPDPKA--PANKAFTGFIVEADTPGIQIGRKELNMGQRCSDTRGIVFED 254 Query: 315 VRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIH 374 V+VP ENVL G+GFKVAM + R +AA G + + +A +A R FG+ + Sbjct: 255 VKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEATKYALERKTFGKLLV 314 Query: 375 NFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECI 434 I LA M M + + +D G + A+I+K F + A ++ + + Sbjct: 315 EHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRN-TYYASIAKAFAGDIANQLATDAV 373 Query: 435 QIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGK 482 QI+GG GF E VE+++RD +I++I+EGT+ I RL VA + +DK K Sbjct: 374 QILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREH-IDKYK 420 >2JIF-A nrPDB Length = 404 Score = 399 bits (1025), Expect = e-111, Method: Composition-based stats. Identities = 126/378 (33%), Positives = 205/378 (54%), Gaps = 11/378 (2%) Query: 99 TQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLC 156 T + V +F +E P + D +E++ QGL + G G++V E GG G Sbjct: 30 TDEEMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGAS 89 Query: 157 NTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCL 216 ++E + D V + ++ I GT+ QK YLP+L + E V +FCL Sbjct: 90 FLSTVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTT-EKVGSFCL 148 Query: 217 TEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVK 276 +E +GSD+ +++T A G YY LNGSK+WIS+ A +F V A DP G Sbjct: 149 SEAGAGSDSFALKTRA--DKEGDYYVLNGSKMWISSAEHAGLFLVMA---NVDPTIG--Y 201 Query: 277 EKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHI 336 + IT+F+V+R G+ G PE K+G++AS+T + F+ V+VP N+LG++G G+K A+ Sbjct: 202 KGITSFLVDRDTPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGS 261 Query: 337 LNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESM 396 LN GR G+AA + G +G + + R QFG+++ +F +Q ++A + + Sbjct: 262 LNEGRIGIAAQMLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLL 321 Query: 397 AYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLR 456 Y + ++ G F EA+++K + SE A + T +CI+ MGG+G+ K+ VE+ RD + Sbjct: 322 TYNAARLLEAGK-PFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAK 380 Query: 457 IFRIFEGTNDILRLFVAL 474 I I+EG ++I +A Sbjct: 381 IGTIYEGASNIQLNTIAK 398 >3MDE-A nrPDB Length = 385 Score = 399 bits (1024), Expect = e-111, Method: Composition-based stats. Identities = 116/387 (29%), Positives = 189/387 (48%), Gaps = 8/387 (2%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSEL 150 + E T+ KE +F E P A+ D + ELG +P Sbjct: 1 GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESF 60 Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET 210 GG+GL + E + GV + A ++G +++ G Q++KYL ++ Sbjct: 61 GGLGLGIIDSCLITEELAYGCTGVQTAIEA-NTLGQVPLIIGGNYQQQKKYLGRMTEEPL 119 Query: 211 VAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDP 270 + A+C+TEP +GSD A I+T A G Y +NG K+WI+NGG A+ + + A++ Sbjct: 120 MCAYCVTEPGAGSDVAGIKTKAEKK--GDEYIINGQKMWITNGGKANWYFLLARSDPDPK 177 Query: 271 ATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 A + T F+VE G+ G E MG + S+T + F+ VRVP ENVL G+GF Sbjct: 178 A--PASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGF 235 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 K+AM + R +AA G + + +A +A R FG+ + I LA M M Sbjct: 236 KIAMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKV 295 Query: 391 YVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVER 450 + + +D G + A+I+K + ++ A ++ + +Q+ GG GF E VE+ Sbjct: 296 ELARLSYQRAAWEIDSGRRN-TYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEK 354 Query: 451 VLRDLRIFRIFEGTNDILRLFVALQGC 477 ++RD +I++I+EGT I R+ +A + Sbjct: 355 LMRDAKIYQIYEGTAQIQRIIIAREHI 381 >1RX0-A nrPDB Length = 393 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 118/400 (29%), Positives = 197/400 (49%), Gaps = 11/400 (2%) Query: 80 GQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKEL 139 G + LNEEQ +F K + +R E + A+ D E+ + +L Sbjct: 5 GHRSLTSCIDPSMGLNEEQKEFQKVAFDFAAR--EMAPNMAEWDQKELFPVDVMRKAAQL 62 Query: 140 GAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKE 199 G G+ + +++GG GL + + E + + H + I FG + Q+ Sbjct: 63 GFGGVYIQTDVGGSGLSRLDTSVIFEALATGCTSTTAYISIHN-MCAWMIDSFGNEEQRH 121 Query: 200 KYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIF 259 K+ P L + E A++CLTEP SGSDAAS+ TSA G +Y LNGSK +IS G +DI+ Sbjct: 122 KFCPPLCTMEKFASYCLTEPGSGSDAASLLTSAKKQ--GDHYILNGSKAFISGAGESDIY 179 Query: 260 TVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPS 319 V +T P + I+ VVE+G G++ G EKK+G + T V F+ VP Sbjct: 180 VVMCRTGGPGP------KGISCIVVEKGTPGLSFGKKEKKVGWNSQPTRAVIFEDCAVPV 233 Query: 320 ENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLI 379 N +G G GF +A+ LN GR +A+ G + DH R QFGE + + + Sbjct: 234 ANRIGSEGQGFLIAVRGLNGGRINIASCSLGAAHASVILTRDHLNVRKQFGEPLASNQYL 293 Query: 380 QEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGG 439 Q LA M M + + + D +++K+F ++ + + ++ +Q+ GG Sbjct: 294 QFTLADMATRLVAARLMVRNAAVALQEERKDAVALCSMAKLFATDECFAICNQALQMHGG 353 Query: 440 MGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMD 479 G++K+ V++ +RD R+ +I EG+N+++R+ ++ + Sbjct: 354 YGYLKDYAVQQYVRDSRVHQILEGSNEVMRILISRSLLQE 393 >2PG0-A nrPDB Length = 385 Score = 392 bits (1006), Expect = e-109, Method: Composition-based stats. Identities = 120/389 (30%), Positives = 190/389 (48%), Gaps = 13/389 (3%) Query: 93 VLNEEQTQFLKE----LVEPVSRFFEEVNDPAKNDALE--MVEETTWQGLKELGAFGLQV 146 LN ++L+E +F E+ P ND + ++ + W + E G V Sbjct: 1 GLNHMTARYLREEHHMFRAAFRKFLEKEAYPHYNDWEKRGIIPRSFWAKMGENGFLCPWV 60 Query: 147 PSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 + GG+ + E + + + +G H I I +GT+ QK+K+LPK Sbjct: 61 DEKYGGLNADFAYSVVINEELEKVGSSL-VGIGLHNDIVTPYIASYGTEEQKQKWLPKCV 119 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 +GE + A +TEP +GSD A+I T+AV G YY +NG K +I+NG AD+ V KT Sbjct: 120 TGELITAIAMTEPGAGSDLANISTTAVKD--GDYYIVNGQKTFITNGIHADLIVVACKT- 176 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 DP I+ VVER G T G +K+G+ A +TAE+FF +VP+ N+LGE Sbjct: 177 --DPQAKPPHRGISLLVVERDTPGFTRGRKLEKVGLHAQDTAELFFQDAKVPAYNLLGEE 234 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 G GF M L R +A A + + + RT FG+++ F +Q +LA M Sbjct: 235 GKGFYYLMEKLQQERLVVAIAAQTAAEVMFSLTKQYVKQRTAFGKRVSEFQTVQFRLAEM 294 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + V G E +++K + +E A +V E +Q+ GG G+M+E Sbjct: 295 ATEIALGRTFVDRVIEEHMAGKQ-IVTEVSMAKWWITEMAKRVAAEAMQLHGGYGYMEEY 353 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVALQ 475 + R RD+ + I+ GTN++++ +A Q Sbjct: 354 EIARRYRDIPVSAIYAGTNEMMKTIIARQ 382 >2DVL-A nrPDB Length = 372 Score = 390 bits (1002), Expect = e-109, Method: Composition-based stats. Identities = 141/383 (36%), Positives = 212/383 (55%), Gaps = 15/383 (3%) Query: 98 QTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGL 155 TQ + +++ V R EV P + D + L ELG G+ P E GGVGL Sbjct: 3 LTQEQRLVLDAVRRVAREVLYPLAPEYDRKAEYPWPQLKALAELGLLGMTTPEEWGGVGL 62 Query: 156 CNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFC 215 + +A +E + D V + + + +L FG++AQK +YL LA GE + AFC Sbjct: 63 DSVTWALALEELAAADPSVAVIVSVTSGLPQYMLLRFGSEAQKRRYLVPLARGEWIGAFC 122 Query: 216 LTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAV 275 LTEP +GSDA S+R A G + LNG K WI++ G A ++ V A+T Sbjct: 123 LTEPQAGSDAKSLRAEARRVKGG--FVLNGVKSWITSAGHAHLYVVMART---------- 170 Query: 276 KEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMH 335 ++ I+AF+VE+G G++ G PE+KMG+ A++TAEV + V VP EN+LGE G G A+ Sbjct: 171 EKGISAFLVEKGTPGLSFGRPEEKMGLHAAHTAEVRLEEVFVPEENLLGEEGRGLAYALA 230 Query: 336 ILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTES 395 L++GR G+AA G RG A +A R QFG+K+ I K+A M + + Sbjct: 231 GLDSGRVGVAAQAVGIARGAFEIAKAYAEEREQFGKKLKEHQAIAFKIADMHVKIAAARA 290 Query: 396 MAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDL 455 + + D+G F +EA+ +K+F S AA +VT E +Q++GG G+ ++ VER RD Sbjct: 291 LVLEAARKKDRGER-FTLEASAAKLFASAAAVEVTREAVQVLGGYGYHRDYRVERYYRDA 349 Query: 456 RIFRIFEGTNDILRLFVALQGCM 478 ++ I+EGT++I RL +A + Sbjct: 350 KVTEIYEGTSEIQRLVIARELYR 372 >4IV6-A nrPDB Length = 388 Score = 386 bits (992), Expect = e-107, Method: Composition-based stats. Identities = 120/390 (30%), Positives = 186/390 (47%), Gaps = 11/390 (2%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGG 152 L E+ +K + + V + + V ++ E + +KE+G FGL +P G Sbjct: 6 ALTAEEETIVKTVHDFVEKQVKPVVRELEH--ANTYPEELIETMKEIGIFGLAIPEPYGF 63 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVA 212 + Y ++ E + + + +G H + K +LLFGT+ QK+KYLP++A+GE A Sbjct: 64 GAVSMPCYVQVAEELARGWMSLAGAMGGHT-VVSKLLLLFGTEEQKQKYLPRMATGELRA 122 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 LTEP GSD ++RT A G Y +NGSK WISN +D+ + KT DP Sbjct: 123 TMALTEPGGGSDLQAMRTVARRD--GDDYVINGSKTWISNARRSDLVALMCKT---DPDA 177 Query: 273 GAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGE-VGSGFK 331 + ++ +VE+ G K+G K + E+ F RVP ++LG+ G GF Sbjct: 178 QPAHKGVSILLVEK-VPGFDVSRDLPKLGYKGVESCELNFTDARVPVSSLLGDDEGRGFA 236 Query: 332 VAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQY 391 M L GR +AA G R A+ ++ R FG+ I + LA M Y Sbjct: 237 QMMKGLEVGRLQVAARATGVARAAFEDALRYSQERESFGKPIWQHQSVGNMLADMGTKLY 296 Query: 392 VTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERV 451 S+ + D G +EA ++K+F SE A ++ + +++ GG G+ E VER Sbjct: 297 AARSLLLSAAEKFDAGQR-CDMEAGMAKLFASETAMQIALDAVRVHGGYGYSTEYDVERY 355 Query: 452 LRDLRIFRIFEGTNDILRLFVALQGCMDKG 481 RD + + EGTN+I R +A Q G Sbjct: 356 FRDAPLMIVGEGTNEIQRNVIAKQLVARGG 385 >3NF4-A nrPDB Length = 387 Score = 384 bits (987), Expect = e-107, Method: Composition-based stats. Identities = 131/393 (33%), Positives = 215/393 (54%), Gaps = 14/393 (3%) Query: 85 DQVFPYPSVLNEEQ-TQFLKELVEPVSRFFEEVNDPA--KNDALEMVEETTWQGLKELGA 141 +P ++ +Q EL+E ++V DP +++ E E ++ L G Sbjct: 2 PGSMIHPMAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGAAGL 61 Query: 142 FGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKY 201 L P E GG G Y +++E + V + + H S+ +L+FGT+ QK+++ Sbjct: 62 LSLPQPEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVH-SLSSHPLLVFGTEEQKKRW 120 Query: 202 LPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTV 261 LP + SGE + A+ L+EP +GSDAA++R +A P+ G Y +NGSK WI++GG AD +T+ Sbjct: 121 LPGMLSGEQIGAYSLSEPQAGSDAAALRCAATPTDGG--YVINGSKSWITHGGKADFYTL 178 Query: 262 FAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSEN 321 FA+T G ++ F+V G++ G PE+KMG+ A T F+D R+ ++ Sbjct: 179 FART-------GEGSRGVSCFLVPADQPGLSFGKPEEKMGLHAVPTTSAFYDNARIDADR 231 Query: 322 VLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQE 381 +GE G G ++A L++GR G+AA G + + +AV +A RT FG KI + + Sbjct: 232 RIGEEGQGLQIAFSALDSGRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGF 291 Query: 382 KLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMG 441 LA M + + DQG + +A+I+K+ ++AA KVT + +Q+ GG+G Sbjct: 292 LLADMAAAVATARATYLDAARRRDQG-RPYSQQASIAKLTATDAAMKVTTDAVQVFGGVG 350 Query: 442 FMKEPGVERVLRDLRIFRIFEGTNDILRLFVAL 474 + ++ VER +R+ +I +IFEGTN I RL +A Sbjct: 351 YTRDYRVERYMREAKIMQIFEGTNQIQRLVIAR 383 >3GNC-A nrPDB Length = 399 Score = 384 bits (986), Expect = e-107, Method: Composition-based stats. Identities = 118/386 (30%), Positives = 184/386 (47%), Gaps = 12/386 (3%) Query: 91 PSVLNEEQTQFLKELVEPVSRFFEEVNDPAKND--ALEMVEETTWQGLKELGAFGLQVPS 148 P +L+++ + + + + + P + E + ++ + E+G G +P Sbjct: 15 PLLLDQQLADDERMVRDAAHAYAQGKLAPRVTEAFRHETTDAAIFREMGEIGLLGPTIPE 74 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 208 + GG GL Y + V D G + S+ I FG+ AQKEKYLPKLA+G Sbjct: 75 QYGGPGLDYVSYGLIAREVERVDSGYRSMMSVQSSLVMVPIFEFGSDAQKEKYLPKLATG 134 Query: 209 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 268 E + F LTEP+ GSD S+ T A P G Y+L+GSK+WI+N +AD+F V+AK Sbjct: 135 EWIGCFGLTEPNHGSDPGSMVTRARKVPGG--YSLSGSKMWITNSPIADVFVVWAKLDED 192 Query: 269 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 328 +++I F++E+G G++ K+G++AS T E+ D VP EN+L V Sbjct: 193 G------RDEIRGFILEKGCKGLSAPAIHGKVGLRASITGEIVLDEAFVPEENILPHV-K 245 Query: 329 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 388 G + LN+ R+G+A G A + +R QFG + LIQ+KLA M Sbjct: 246 GLRGPFTCLNSARYGIAWGALGAAESCWHIARQYVLDRKQFGRPLAANQLIQKKLADMQT 305 Query: 389 LQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV 448 + + D+G +I +I K A + ++GG G E GV Sbjct: 306 EITLGLQGVLRLGRMKDEGTAAVEI-TSIMKRNSCGKALDIARLARDMLGGNGISDEFGV 364 Query: 449 ERVLRDLRIFRIFEGTNDILRLFVAL 474 R L +L + +EGT+DI L + Sbjct: 365 ARHLVNLEVVNTYEGTHDIHALILGR 390 >3MPI-A nrPDB Length = 397 Score = 380 bits (976), Expect = e-105, Method: Composition-based stats. Identities = 120/387 (31%), Positives = 193/387 (49%), Gaps = 12/387 (3%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 L++E KE+ V++ D N+ EE + + ELG FG +P E GG Sbjct: 5 LSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAV-RPMGELGFFGTVIPEEYGGE 63 Query: 154 GLC--NTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 G+ + E + + + L IL +G++A K+KY+PKL+S E + Sbjct: 64 GMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSAEFL 123 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPA 271 F +TEP +GSD ++ ++A G ++ LNGSK WISN AD+ +A T Sbjct: 124 GGFGITEPDAGSDVMAMSSTA--EDKGDHWLLNGSKTWISNAAQADVLIYYAYTD----- 176 Query: 272 TGAVKEKITAFVV-ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 A ++AFV+ R F GI E K+G AS T E+F D V+VP EN+LG+ G G Sbjct: 177 KAAGSRGLSAFVIEPRNFPGIKTSNLE-KLGSHASPTGELFLDNVKVPKENILGKPGDGA 235 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 ++ LN+ R AA G + + A+ + R QFG+ I +F + Q+ +A+M + Sbjct: 236 RIVFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEV 295 Query: 391 YVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVER 450 +AY +A D+G + ++ A++K EA K + ++I+G G+ E V R Sbjct: 296 EAARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVAR 355 Query: 451 VLRDLRIFRIFEGTNDILRLFVALQGC 477 RD + + EG+ +I ++ +AL Sbjct: 356 FYRDAPTYYMVEGSANICKMIIALDQL 382 >4IRN-A nrPDB Length = 416 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 122/388 (31%), Positives = 200/388 (51%), Gaps = 12/388 (3%) Query: 89 PYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPS 148 + N +Q QF K++++ + ++D KND E+ WQ E G G +P+ Sbjct: 35 EFDFAWNSQQIQFRKKVIQFAQQSL--ISDLIKNDKEEIFNRDAWQKCSEFGVHGWPIPA 92 Query: 149 ELGGVGLCNTQYARLVEIVGMH--DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 GG L A ++ +G D G+ + AH +L FGT+ QKEKYLP L Sbjct: 93 RYGGQELDILTTAYALQGLGYGCKDNGLIFAMNAHIWACEMPLLTFGTEEQKEKYLPLLC 152 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 G +A+ TEP +GSD S++T+A G Y LNG K +++NG +AD+F +FA Sbjct: 153 RGGWIASHAATEPQAGSDIYSLKTTAQKD--GDKYILNGYKHYVTNGTIADLFIIFATI- 209 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 DP+ G KE +T F++E+ G+ P KMG++ + E+ + V + N LGE Sbjct: 210 --DPSLG--KEGLTTFMIEKDTPGLILSKPISKMGMRTAEVPELRLENCEVSAANRLGEE 265 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 G+G + H + R + AA GTM ++ +++ +A + QFG+ I F L+ KL M Sbjct: 266 GTGLAIFNHSMEWERGFILAAAVGTMERLLEQSIRYARSHKQFGQAIGKFQLVANKLVEM 325 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + ++ Y V+ M + +EA+++ ++ SEA + E I+I G G++ Sbjct: 326 KLRLENAKAYLYKVAW-MKENKQMALLEASMANLYISEAWVQSCLEAIEIHGAYGYLTNT 384 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVAL 474 +ER LRD + + GT++I R+ +A Sbjct: 385 ELERELRDAIASKFYSGTSEIQRVVIAK 412 >2EBA-A nrPDB Length = 385 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 114/400 (28%), Positives = 184/400 (46%), Gaps = 24/400 (6%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALE--MVEETTWQGLKELGAFGLQVPSEL 150 L + T KE+ + RF E+ P D E + ELG G +P E Sbjct: 6 ALEDLLTPEEKEVQKAARRFLEKEALPHIRDWWEEGVFPTHLIPRFAELGFLGPTLPPEY 65 Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET 210 GG G+ + Y + + D G+ + S+ I +G++ QK ++LPKLA GE Sbjct: 66 GGAGVSSAAYGLICYELERVDSGLRSFVSVQSSLVMYPIYAYGSEEQKREFLPKLARGEM 125 Query: 211 VAAFCLTEPSSGSDA-ASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 V F LTEP GSD +++T A G + LNG+K+WI+NG LA + ++AK + Sbjct: 126 VGCFGLTEPDGGSDPYGNMKTRARRE--GDTWVLNGTKMWITNGNLAHLAVIWAKDEGGE 183 Query: 270 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG 329 + F+V G ++KM ++AS T+E+ + VRVP L + G Sbjct: 184 ---------VLGFLVPTDTPGFQAREVKRKMSLRASVTSELVLEEVRVPESLRLPKA-LG 233 Query: 330 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML 389 K + L RFG+A G + + +AV A +R+ FGE + L+Q KLA M+ Sbjct: 234 LKAPLSCLTQARFGIAWGAMGALEAVYEEAVAFAKSRSTFGEPLAKKQLVQAKLAEMLAW 293 Query: 390 QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 449 +A+ ++ D+G + +++K A + I+GG G E Sbjct: 294 HTEGLLLAWRLARLKDEGKLTP-AQVSLAKRQNVWKALQAARMARDILGGSGITLEYHAI 352 Query: 450 RVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 489 R + +L +EGT+D+ L + G+E++GL + Sbjct: 353 RHMLNLETVYTYEGTHDVHTLVL--------GREITGLNA 384 >2CX9-A nrPDB Length = 387 Score = 371 bits (952), Expect = e-103, Method: Composition-based stats. Identities = 143/387 (36%), Positives = 213/387 (55%), Gaps = 6/387 (1%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSEL 150 L E+ ++++ P F + P A+ D + L E G FG VP Sbjct: 2 GLWFEEGAEERQVLGPFREFLKAEVAPGAAERDRTGAFPWDLVRKLAEFGVFGALVPEAY 61 Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET 210 GG GL +AR+VE + +D + +T+ +H S+ ILL G++AQKE +LPKLASGE Sbjct: 62 GGAGLSTRLFARMVEAIAYYDGALALTVASHNSLATGHILLAGSEAQKEAFLPKLASGEA 121 Query: 211 VAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDP 270 + A+ LTEP SGSDAA+++T A G + LNG+K +I+ G +A ++ V A+T P Sbjct: 122 LGAWGLTEPGSGSDAAALKTKAEKVEGG--WRLNGTKQFITQGSVAGVYVVMARTD-PPP 178 Query: 271 ATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGF 330 + + I+AF R G+ G E+K+G+ AS+TA++ + + VP E +LGE G GF Sbjct: 179 SPERKHQGISAFAFFRPERGLKVGRKEEKLGLTASDTAQLILEDLFVPEEALLGERGKGF 238 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQ 390 + +L+ GR G+AA G + + A+ +A R FG I F + KLA Sbjct: 239 YDVLRVLDGGRIGIAAMAVGLGQAALDYALAYAKGREAFGRPIAEFEGVSFKLAEAATEL 298 Query: 391 YVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVER 450 + + D G F +EAA +K+F SEAA K DE IQI+GG G++K+ VER Sbjct: 299 EAARLLYLKAAELKDAG-RPFTLEAAQAKLFASEAAVKACDEAIQILGGYGYVKDYPVER 357 Query: 451 VLRDLRIFRIFEGTNDILRLFVALQGC 477 RD R+ RI EGT++IL+L +A + Sbjct: 358 YWRDARLTRIGEGTSEILKLVIARRLL 384 >4W9U-A nrPDB Length = 395 Score = 369 bits (947), Expect = e-102, Method: Composition-based stats. Identities = 110/388 (28%), Positives = 177/388 (45%), Gaps = 13/388 (3%) Query: 89 PYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDA--LEMVEETTWQGLKELGAFGLQV 146 P +L E+ T+ + + + F +V P A E + + + + G G+ + Sbjct: 10 EDPFLLEEQLTEDERMIRDSAKAFASDVLLPRVEKAYLEETTDPELFHLMGQAGLLGVTL 69 Query: 147 PSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 P + G Y + V D G + S+ I +G+ Q++KYLP L Sbjct: 70 PEDYGAANASYVAYGLVAREVERIDSGYRSMMSVQSSLVMYPIYAYGSDEQRKKYLPGLV 129 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 SGE + F LTEP +GSD A ++T A G Y L+GSK+WISN +AD+F V+AK+ Sbjct: 130 SGELIGCFGLTEPDAGSDPAGMKTRAEKIDGG--YRLSGSKMWISNSPIADVFVVWAKSA 187 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 D A I F++E+G G++ K+ ++AS T E+ DGV V + +L V Sbjct: 188 AHDNA-------IRGFILEKGMKGLSAPKIGGKLSLRASITGEIVMDGVEVSEDAILPNV 240 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 SG K LN R+G++ + G +A + +R QF + + L Q+KLA M Sbjct: 241 -SGLKGPFGCLNRARYGISWGVLGAAEDCWFRARQYGLDRKQFNKPLAGTQLYQKKLADM 299 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + V D+G ++ +I K A + + + GG G E Sbjct: 300 QTEIALGIQASLRVGRLFDEGKMAPEM-ISIVKRNNCGKALDIARQARDMHGGNGIQIEY 358 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVAL 474 V R ++L +EGT+D+ L + Sbjct: 359 HVMRHAQNLETVNTYEGTHDVHALILGR 386 >1SIR-A nrPDB Length = 394 Score = 364 bits (933), Expect = e-100, Method: Composition-based stats. Identities = 113/386 (29%), Positives = 176/386 (45%), Gaps = 14/386 (3%) Query: 91 PSVLNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPS 148 P VL E+ T + + + +E P + E+ + ELG G + Sbjct: 9 PLVLEEQLTTDEILIRDTFRTYCQERLMPRILLANRNEVFHREIISEMGELGVLGPTI-K 67 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 208 G G+ + Y L + D G + S+ I +G++ Q++KYLP+LA G Sbjct: 68 GYGCAGVSSVAYGLLARELERVDSGYRSAMSVQSSLVMHPIYAYGSEEQRQKYLPQLAKG 127 Query: 209 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 268 E + F LTEP+SGSD +S+ T A + K YTLNG+K WI+N +AD+F V+A+ Sbjct: 128 ELLGCFGLTEPNSGSDPSSMETRAHYNSSNKSYTLNGTKTWITNSPMADLFVVWARCEDG 187 Query: 269 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 328 I F++E+G G++ + K ++AS T + DGV VP ENVL S Sbjct: 188 ---------CIRGFLLEKGMRGLSAPRIQGKFSLRASATGMIIMDGVEVPEENVLPGASS 238 Query: 329 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 388 LNN R+G+A + G + A +A +R QFG + LIQ+KLA M+ Sbjct: 239 -LGGPFGCLNNARYGIAWGVLGASEFCLHTARQYALDRMQFGVPLARNQLIQKKLADMLT 297 Query: 389 LQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGV 448 + + DQ ++ ++ K A + + ++GG G E V Sbjct: 298 EITLGLHACLQLGRLKDQDKAAPEM-VSLLKRNNCGKALDIARQARDMLGGNGISDEYHV 356 Query: 449 ERVLRDLRIFRIFEGTNDILRLFVAL 474 R +L +EGT+DI L + Sbjct: 357 IRHAMNLEAVNTYEGTHDIHALILGR 382 >3SF6-A nrPDB Length = 403 Score = 363 bits (932), Expect = e-100, Method: Composition-based stats. Identities = 113/405 (27%), Positives = 178/405 (43%), Gaps = 24/405 (5%) Query: 85 DQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGL 144 D + +VL+ E+ + + V R + D E + L ELG G+ Sbjct: 21 DDLIGINAVLSAEEREIRDTVRSVVQRRIKPHIASWYEDGELPARELAVE-LGELGLLGM 79 Query: 145 QVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPK 204 + G G+ Y + D G+ + S+ I FG+ QK+++LP Sbjct: 80 HL-KGYGCAGMSAVAYGLACLELEAGDSGIRSLVSVQGSLAMYAIHAFGSDEQKDQWLPD 138 Query: 205 LASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAK 264 +ASG + F LTEP GSD A +RT A G + L G+K+WI+NG +AD+ V+A+ Sbjct: 139 MASGHRIGCFGLTEPDHGSDPAGMRTRATR--SGDDWILTGTKMWITNGSVADVAVVWAR 196 Query: 265 TPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLG 324 T E I FVV G T + KM ++AS T+E+ DGVR+P L Sbjct: 197 TD----------EGIRGFVVPTDTPGFTANTIKSKMSLRASVTSELVLDGVRLPDSARLP 246 Query: 325 EVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLA 384 S + LN RFG+ G R + A+ +A +R QF I F L Q+KLA Sbjct: 247 GATS-LGAPLRCLNEARFGIVFGALGAARDCLETALAYACSREQFDRPIGGFQLTQQKLA 305 Query: 385 RMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMK 444 M + +A + D G + + ++ K+ A ++ ++G G Sbjct: 306 DMTLEYGKGFLLALHLGRQKDAGELAPE-QVSLGKLNNVREAIEIARTARTVLGASGITG 364 Query: 445 EPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 489 E V R +L +EGT+++ L + G+ L+G+G+ Sbjct: 365 EYPVMRHANNLESVLTYEGTSEMHTLII--------GQALTGVGA 401 >6CY8-B nrPDB Length = 380 Score = 355 bits (912), Expect = 2e-98, Method: Composition-based stats. Identities = 110/386 (28%), Positives = 182/386 (47%), Gaps = 14/386 (3%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELG-- 151 +N E T EL E RF +E++ P + D W L + G FGL +P + Sbjct: 1 MNFEWTHEQAELFEHALRFGKELSAPLQED--NGFPRDNWNALGDFGYFGLPIPEKYAKD 58 Query: 152 GVGLCNTQYARLVEIVGMHDLGVGITLG--AHQSIGFKGILLFGTKAQKEKYLPKLASGE 209 G G +++E +G G+ AH IL G++ K + LP LA+G Sbjct: 59 GSGFDILTTIKIIEGLGQSCTDTGLLFAGAAHTFACSMPILEHGSETLKHQLLPDLATGR 118 Query: 210 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 +AA ++E S+GSD +++ T+A G YY LNG K +++NG +AD + V+A T Sbjct: 119 KIAANAISEASAGSDISNLATTAQKE--GDYYVLNGGKSYVTNGSIADYYVVYATTNKKH 176 Query: 270 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG 329 G TAFVV R GI+ G K+G++++ +VFFD + + LG G G Sbjct: 177 GYLGQ-----TAFVVPRNTPGISVGNDYHKLGLRSAPLNQVFFDNCTIHKDYALGREGQG 231 Query: 330 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML 389 ++ ++ R + A G M+ + + +++A R Q + I F + ++A M + Sbjct: 232 ARIFAASMDWERCCLFAIFVGAMQRDLNQCIEYANTRMQGDKTISRFQAVSHRIADMGVR 291 Query: 390 QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 449 M Y + Q D A+SK+ SEA + + I++ G +G++ E V Sbjct: 292 LESARLMLYYAAWQKSQ-DVDNTKAVAMSKLAISEAFVQSGIDSIRVHGALGYLDEGRVN 350 Query: 450 RVLRDLRIFRIFEGTNDILRLFVALQ 475 ++D +F GT+DI R + + Sbjct: 351 NSIKDALGSVLFSGTSDIQRELICNR 376 >3SWO-A nrPDB Length = 399 Score = 348 bits (893), Expect = 4e-96, Method: Composition-based stats. Identities = 103/389 (26%), Positives = 170/389 (43%), Gaps = 25/389 (6%) Query: 100 QFLKELVEPVSRFFEEVNDPAKNDALE--MVEETTWQGLKELGAFGLQVPSELGGVGLCN 157 Q +++ V +F + P E + + LG G+ + G G Sbjct: 28 QDERDIAATVRQFVDTRLKPNVEGWFESATLPSELAKEFGNLGVLGMHL-QGYGCAGTNA 86 Query: 158 TQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLT 217 Y + D G + S+ I +G++ QK ++LP+LA+G+ + F LT Sbjct: 87 VSYGLACMELEAGDSGFRSFVSVQGSLSMFSIYRYGSEEQKNEWLPRLAAGDAIGCFGLT 146 Query: 218 EPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKE 277 EP GS+ A +RT A G + LNG+K+WI+NG LAD+ TV+A+T Sbjct: 147 EPDFGSNPAGMRTRARRD--GSDWILNGTKMWITNGNLADVATVWAQTDD---------- 194 Query: 278 KITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHIL 337 I F+V G T +K+ ++AS T+E+ D VR+P+ L + G + L Sbjct: 195 GIRGFLVPTDTPGFTANEIHRKLSLRASVTSELVLDNVRLPASAQL-PLAEGLSAPLSCL 253 Query: 338 NNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMA 397 N RFG+ G R + + + +R F + + N+ L QEKLA M + +A Sbjct: 254 NEARFGIVFGALGAARDSLETTIAYTQSREVFDKPLSNYQLTQEKLANMTVELGKGMLLA 313 Query: 398 YMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRI 457 + D + + ++ K+ A + EC ++GG G E R +L Sbjct: 314 IHLGRIKDAEGVRPE-QISLGKLNNVREAIAIARECRTLLGGSGITLEYSPLRHANNLES 372 Query: 458 FRIFEGTNDILRLFVALQGCMDKGKELSG 486 +EGT+++ L + GK L+G Sbjct: 373 VLTYEGTSEMHLLSI--------GKALTG 393 >6ES9-A nrPDB Length = 551 Score = 344 bits (883), Expect = 6e-95, Method: Composition-based stats. Identities = 127/391 (32%), Positives = 194/391 (49%), Gaps = 22/391 (5%) Query: 100 QFLKELVEPVSRFFEEVNDPAKNDA---LEMVEETTWQGLKELGAFGLQVPSELGGVGLC 156 + L+ + + R+ EE P ++ +++ + L ELG FGL +P E GG+GL Sbjct: 169 EDLEMIRDQFRRYAEERVIPNAHEWHLKDQLIPMEIIEELAELGVFGLTIPEEFGGLGLS 228 Query: 157 NTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCL 216 + E + +GVG +LG I + IL GT+AQK K+LP LASGE ++ Sbjct: 229 KASMVVVTEELSRGYIGVG-SLGTRSEIAAELILCGGTEAQKAKWLPGLASGEILSTAVF 287 Query: 217 TEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVK 276 TEP++GSD S+RT AV G+ + + G+K WI++ + T+ A+T DP T Sbjct: 288 TEPNTGSDLGSLRTRAVRD--GEDWVVTGNKTWITHAQRTHVMTLLART---DPETTDW- 341 Query: 277 EKITAFVVER---------GFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL-GEV 326 ++ F+ E+ G+T G E +G + E+ FDG R+ EN+L GE Sbjct: 342 RGLSMFLAEKEPGTDDDPFPTPGMTGGEIE-VLGYRGMKEYELGFDGFRIKGENLLGGEP 400 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 G GFK M + R AA G + + +A +R QFG+ + F + +KLA M Sbjct: 401 GRGFKQLMETFESARIQTAARAVGVAQSAAEIGMRYAVDRKQFGKSLIEFPRVADKLAMM 460 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + + Y + D G +EA ++K+ G+ AW D +QI GG GF E Sbjct: 461 AVEIMIARQLTYFSAWEKDHGRR-CDLEAGMAKLLGARVAWAAADNALQIHGGNGFALEY 519 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVALQGC 477 + RVL D RI IFEG +I +A + Sbjct: 520 AISRVLCDARILNIFEGAAEIQAQVIARRLL 550 >5ZW7-A nrPDB Length = 402 Score = 342 bits (877), Expect = 3e-94, Method: Composition-based stats. Identities = 110/408 (26%), Positives = 192/408 (47%), Gaps = 18/408 (4%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDP--AKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 ++ + ++ E RF +V D + +++ W+ G V + G Sbjct: 1 MDFNLSNSQSDIYESAYRFACDVLDQDAQTRISQKILSTELWKKAAAYGFAHGPVSHQFG 60 Query: 152 GVGLCNTQYARLVEIVGMH--DLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE 209 G L A ++E +G D+G+ +L AH + FG+ K+KYL L +G+ Sbjct: 61 GSELGALDTALMIEALGKGSRDIGLSFSLCAHLCACVIPLYRFGSSELKDKYLESLVTGK 120 Query: 210 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 +AA TEP +GSD +++ +A P G Y LNG K++I+N +AD+F ++AKT + Sbjct: 121 LIAANAATEPDAGSDIYNMQATAQPCEGG--YILNGKKIFITNAPIADVFIIYAKT---N 175 Query: 270 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSG 329 P G + ++AF++E+G G+ G K + +E+ F+ + +P +G G+G Sbjct: 176 PDHGFL--GVSAFLIEKGTPGLNVGEVIPKDCLSNCPWSEIVFNDIFIPQSQRIGMEGAG 233 Query: 330 FKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVML 389 + + + ++A G + ++ +++A R QFG+ I F + ++ M + Sbjct: 234 GAIFHDSMIWEKGCLSALFVGGLARLLETTLEYAKARQQFGKAIGQFQSVSNRIIDMKLR 293 Query: 390 QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVE 449 M Y DQG D + + A+SK+ SE A + + IQ GG +E G+ Sbjct: 294 LEQCRLMLYRACWKHDQG-QDAEADIAMSKLLISEYAVQSGLDAIQTFGGAAMDQELGLV 352 Query: 450 RVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGN 497 R L ++ RIF GTNDI + +A + L G S P G+ Sbjct: 353 RHLLNMIPSRIFSGTNDIQKEIIARKL------GLRGTSSGSLVPRGS 394 >3R7K-A nrPDB Length = 403 Score = 336 bits (862), Expect = 1e-92, Method: Composition-based stats. Identities = 113/389 (29%), Positives = 175/389 (44%), Gaps = 21/389 (5%) Query: 89 PYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPS 148 P L++ F++ + P +E V + ++ L E+G G+ P Sbjct: 31 PERRALSQMARSFVEREIAPKLAEWEHVGEIPRDLHLNA---------AEVGLLGIGFPE 81 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGI--TLGAHQSIGFKGILLFGTKAQKEKYLPKLA 206 E+GG G A + E + G+ L H I I G+ A E+Y+ Sbjct: 82 EVGGSGGNAIDSALVTEAILAAGGSTGVCAALFTH-GIALPHIAANGSDALIERYVRPTL 140 Query: 207 SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 +G+ + + +TEP +GSD A++RT AV G Y +NG+K +I++G AD T +T Sbjct: 141 AGKMIGSLGVTEPGAGSDVANLRTRAVRE--GDTYVVNGAKTFITSGVRADFVTTAVRTG 198 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 G ++ V+++ G KMG + S+TAE+ F VRVP++N++G Sbjct: 199 ------GPGYGGVSLLVIDKNSPGFEVSRRLDKMGWRCSDTAELSFVDVRVPADNLVGAE 252 Query: 327 GSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 SGF M R G+A T + A A R FG + +I+ KLA M Sbjct: 253 NSGFLQIMQQFQAERLGIAVQAYATAGRALDLAKSWARERETFGRPLTGRQIIRHKLAEM 312 Query: 387 VMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 V + V G D E +++K A V +E +QI GGMG+M+E Sbjct: 313 ARQVDVACTYTRAVMQRWLAGE-DVVAEVSMAKNTAVYACDYVVNEAVQIFGGMGYMRES 371 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVALQ 475 +ER RD RI I GTN+I+ +A + Sbjct: 372 EIERHYRDCRILGIGGGTNEIMNEVIAKR 400 >5IDU-A nrPDB Length = 410 Score = 332 bits (850), Expect = 4e-91, Method: Composition-based stats. Identities = 125/390 (32%), Positives = 189/390 (48%), Gaps = 14/390 (3%) Query: 103 KELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVP-SELGGVG--LCNTQ 159 +EL + + + ++D + + L E G V ++ GG G + Sbjct: 31 RELAAGIEAWATQHLACVQHDDTDTTCRKLVRALGEAGWLKYGVGGAQYGGHGDTIDTRA 90 Query: 160 YARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEP 219 L E + HD G+ A Q +G I L GT QK +YLP+++ GE +AAF L+EP Sbjct: 91 VCLLRETLANHD-GLADFALAMQGLGSGAITLAGTHEQKIRYLPRVSKGEAIAAFALSEP 149 Query: 220 SSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKI 279 +GSD A++ A G Y ++G K WISNGG+AD + VFA+T A G I Sbjct: 150 DAGSDVAAMSLQARAE--GDCYVIDGDKTWISNGGIADFYVVFARTGEAPGARG-----I 202 Query: 280 TAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNN 339 +AF+V+ G+ I A + FD RVP +LG G GFK+AM L+ Sbjct: 203 SAFIVDADTPGLQIAERIDV--IAPHPLARLHFDSARVPRSQMLGAPGEGFKIAMRTLDV 260 Query: 340 GRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYM 399 R +AAA G R + + + A +R FG+ + +F L Q KLA+M + + + Y Sbjct: 261 FRTSVAAASLGFARRALQEGLARAASRKMFGQTLGDFQLTQTKLAQMALTIDSSALLVYR 320 Query: 400 VSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFR 459 + DQG + EAA++K SE A +V D +Q+ GGMG VER+ R++R R Sbjct: 321 AAWLRDQGE-NVTREAAMAKWHASEGAQQVIDAAVQLWGGMGVQSGTTVERLYREIRALR 379 Query: 460 IFEGTNDILRLFVALQGCMDKGKELSGLGS 489 I+EG ++ +L V + + Sbjct: 380 IYEGATEVQQLIVGRDLLKAHAAQRQQERA 409 >2IX5-A nrPDB Length = 436 Score = 330 bits (845), Expect = 2e-90, Method: Composition-based stats. Identities = 108/406 (26%), Positives = 173/406 (42%), Gaps = 23/406 (5%) Query: 84 TDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFG 143 T + + +L E+ K++ E + + + A L +G G Sbjct: 45 TSDYYHFNDLLTPEEQAIRKKVRECMEKEVAPIMTEYWEKAE--FPFHITPKLGAMGVAG 102 Query: 144 LQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLP 203 + G GL T A + D + H S+G I L G++AQKEKYLP Sbjct: 103 GSI-KGYGCPGLSITANAIATAEIARVDASCSTFILVHSSLGMLTIALCGSEAQKEKYLP 161 Query: 204 KLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFA 263 LA TVA + LTEP +GSDA+ + T+A G + +NG K WI N AD+ +FA Sbjct: 162 SLAQLNTVACWALTEPDNGSDASGLGTTATKVEGG--WKINGQKRWIGNSTFADLLIIFA 219 Query: 264 KTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL 323 + T+ +I F+V++ G+ K+G++ ++ V VP E+ L Sbjct: 220 RNTTTN--------QINGFIVKKDAPGLKATKIPNKIGLRMVQNGDILLQNVFVPDEDRL 271 Query: 324 GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKL 383 V S F+ +L R +A G GI + R QFG + F L Q+KL Sbjct: 272 PGVNS-FQDTSKVLAVSRVMVAWQPIGISMGIYDMCHRYLKERKQFGAPLAAFQLNQQKL 330 Query: 384 ARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFM 443 +M+ M + + + G +A++ K + S A + +++GG G + Sbjct: 331 VQMLGNVQAMFLMGWRLCKLYETGQMTPG-QASLGKAWISSKARETASLGRELLGGNGIL 389 Query: 444 KEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGS 489 + V + DL +EGT DI L G+E++G+ S Sbjct: 390 ADFLVAKAFCDLEPIYTYEGTYDINTLV--------TGREVTGIAS 427 >2WBI-A nrPDB Length = 428 Score = 325 bits (833), Expect = 4e-89, Method: Composition-based stats. Identities = 90/400 (22%), Positives = 165/400 (41%), Gaps = 20/400 (5%) Query: 99 TQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKEL----GAFGLQVPSELGGVG 154 F+K+ + P + E +N + + LKE+ G + L +P+ G Sbjct: 35 KHFMKQHILPAEKEVTEFYVQNENSVDKWGKPLVIDKLKEMAKVEGLWNLFLPA---VSG 91 Query: 155 LCNTQYARLVEIVGMHDLGVGITLG-AHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 L + YA + E G + A + + + L+G++ QK+++L L G + Sbjct: 92 LSHVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEEQKKQWLEPLLQGNITSC 151 Query: 214 FCLTEPS-SGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG--GLADIFTVFAKTPVTDP 270 FC+TEP + SDA +I S Y +NG K W S I V +T T Sbjct: 152 FCMTEPDVASSDATNIECSIQRDE--DSYVINGKKWWSSGAGNPKCKIAIVLGRTQNTSL 209 Query: 271 ATGAVKEKITAFVVERGFGGITHGPPEKKMGIKAS---NTAEVFFDGVRVPSENVLGEVG 327 + ++ + +V G+ P G + E+ F+ VRVP+ N++ G Sbjct: 210 SR---HKQHSMILVPMNTPGVKIIRPLSVFGYTDNFHGGHFEIHFNQVRVPATNLILGEG 266 Query: 328 SGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMV 387 GF+++ L GR G + + AT R F +K++ ++ +A Sbjct: 267 RGFEISQGRLGPGRIHHCMRTVGLAERALQIMCERATQRIAFKKKLYAHEVVAHWIAESR 326 Query: 388 MLQYVTESMAYMVSANMDQ-GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + + +MD G+ + E A+ K+ A K+ D IQ+ GG G ++ Sbjct: 327 IAIEKIRLLTLKAAHSMDTLGSAGAKKEIAMIKVAAPRAVSKIVDWAIQVCGGAGVSQDY 386 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSG 486 + + R+ R+ +G +++ +A D+ K L+ Sbjct: 387 PLANMYAITRVLRLADGPDEVHLSAIATMELRDQAKRLTA 426 >5JSC-A nrPDB Length = 410 Score = 311 bits (797), Expect = 5e-85, Method: Composition-based stats. Identities = 125/391 (31%), Positives = 183/391 (46%), Gaps = 14/391 (3%) Query: 103 KELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQY-- 160 +EL + + ++ ++ + L G V G Sbjct: 31 RELAAGIEAWCRANLAHEDHEDVDATCRRLVRELGAAGWLKYGVGGVAYGGHGDTIDTRA 90 Query: 161 -ARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEP 219 L E + H G+ A Q +G I L GT QK +YLP++A+G +AAF L+EP Sbjct: 91 VCLLRETLAKHS-GLADFALAMQGLGSGAISLGGTHEQKTRYLPRVANGTAIAAFALSEP 149 Query: 220 SSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKI 279 +GSD A++ SA G Y L+G K WISNGG+AD + VFA+T A G I Sbjct: 150 EAGSDVAAMTLSAR--EDGDAYVLDGDKTWISNGGIADFYVVFARTGEAPGARG-----I 202 Query: 280 TAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNN 339 +AFVV+ G+ I A + F G RVP +LG G GFK+AM L+ Sbjct: 203 SAFVVDADTPGLEIAERIDV--IAPHPLARLHFAGARVPRSQMLGAPGEGFKLAMRTLDI 260 Query: 340 GRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYM 399 R +AAA G R +A+ V A +R FG+ + +F L Q KLA+M + + + Y Sbjct: 261 FRTSVAAASLGFARHAMAEGVARAASRKMFGQTLGDFQLTQAKLAQMALTIDSSALLVYR 320 Query: 400 VSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFR 459 + DQG + EAA++K SE A +V D +Q+ GGMG VE + R++R R Sbjct: 321 AAWLRDQGE-NVTREAAMAKWHASEGAQQVIDAAVQLYGGMGVQSGTAVEMLYREIRALR 379 Query: 460 IFEGTNDILRLFVALQGCMDKGKELSGLGSA 490 I+EG ++ +L V +G + Sbjct: 380 IYEGATEVQQLIVGRDLLKAHAAATAGANTR 410 >3P4T-A nrPDB Length = 403 Score = 309 bits (791), Expect = 3e-84, Method: Composition-based stats. Identities = 104/387 (26%), Positives = 158/387 (40%), Gaps = 11/387 (2%) Query: 91 PSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEM--VEETTWQGLKELGAFGLQVPS 148 P ++ T + L + V F E P ++ + + ELG G P Sbjct: 19 PGSMSIWTTAEREALRKTVRAFAEREVLPHAHEWERAGEIPRELHRKAAELGLLGAGFPE 78 Query: 149 ELGGVGLCNTQYARLVEIV-GMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLAS 207 + GG G + E + G I ++ G + + Y+ Sbjct: 79 DAGGSGGDGADPVVICEEMHYAGSPGGVYASLFTCGIAVPHMIASGDQRLIDTYVRPTLR 138 Query: 208 GETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPV 267 GE + A +TEP GSD +RT A G +Y +NG+K +I++G AD A+T Sbjct: 139 GEKIGALAITEPGGGSDVGHLRTRA--DLDGDHYVINGAKTYITSGVRADYVVTAARTG- 195 Query: 268 TDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVG 327 G ++ VV++G G KMG ++S+TAE+ + VRVP N++G Sbjct: 196 -----GPGAGGVSLIVVDKGTPGFEVTRKLDKMGWRSSDTAELSYTDVRVPVANLVGSEN 250 Query: 328 SGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMV 387 +GF R G+A + + V+ NR FG + + +Q LA M Sbjct: 251 TGFAQIAAAFVAERVGLATQAYAGAQRCLDLTVEWCRNRDTFGRPLISRQAVQNTLAGMA 310 Query: 388 MLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPG 447 V V G T+ E +K EA V ++ +Q+ GGMG+M E Sbjct: 311 RRIDVARVYTRHVVERQLAGETNLIAEVCFAKNTAVEAGEWVANQAVQLFGGMGYMAESE 370 Query: 448 VERVLRDLRIFRIFEGTNDILRLFVAL 474 VER RD+RI I GT +IL A Sbjct: 371 VERQYRDMRILGIGGGTTEILTSLAAK 397 >1W07-A nrPDB Length = 659 Score = 304 bits (779), Expect = 7e-83, Method: Composition-based stats. Identities = 94/449 (20%), Positives = 171/449 (38%), Gaps = 66/449 (14%) Query: 181 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY 240 H + I GT+ Q++K+L + + + TE GS+ + T+A P Sbjct: 102 HWGMFVPAIKGQGTEEQQKKWLSLANKMQIIGCYAQTELGHGSNVQGLETTATLDPKTDE 161 Query: 241 YTLN-----GSKLWISN-GGLADIFTVFAKTPVTDPATGAVKEKITAFVV-------ERG 287 + ++ SK W G ++ V+A+ G I F+V Sbjct: 162 FVIHTPTQTASKWWPGGLGKVSTHAVVYARLITNGKDYG-----IHGFIVQLRSLEDHSP 216 Query: 288 FGGITHGPPEKKMGIKASNTAE---VFFDGVRVPSENVLGEVGSGFK------------V 332 IT G KMG A N+ + + FD VR+P + +L + + + Sbjct: 217 LPNITVGDIGTKMGNGAYNSMDNGFLMFDHVRIPRDQMLMRLSKVTREGEYVPSDVPKQL 276 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGE-------KIHNFGLIQEK--- 382 + R + A + + + A ++ R QFG ++ ++ Q + Sbjct: 277 VYGTMVYVRQTIVADASNALSRAVCIATRYSAVRRQFGAHNGGIETQVIDYKTQQNRLFP 336 Query: 383 -LARMVMLQYVTESMAYMVSANMDQGA-------TDFQIEAAISKIFGSEAAWKVTDECI 434 LA ++V E + ++ + ++ A + A K + A +EC Sbjct: 337 LLASAYAFRFVGEWLKWLYTDVTERLAASDFATLPEAHACTAGLKSLTTTATADGIEECR 396 Query: 435 QIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNP 494 ++ GG G++ G+ + +EG N +L+L VA K ++ LGS K P Sbjct: 397 KLCGGHGYLWCSGLPELFAVYVPACTYEGDNVVLQLQVARFLM----KTVAQLGSG-KVP 451 Query: 495 FGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE--AKLI 552 G +G A L+ R+G+ ++P++ RAL T + +K Sbjct: 452 VGTTA-YMGRAAHLLQCRSGVQKA---EDWLNPDVVLEA-FEARALRMAVTCAKNLSKFE 506 Query: 553 KHKKGIVNEQFLLQRLADGAIDLYAMVVV 581 ++G Q LL L + AI ++VV Sbjct: 507 NQEQGF---QELLADLVEAAIAHCQLIVV 532 >5AHS-A nrPDB Length = 401 Score = 304 bits (778), Expect = 8e-83, Method: Composition-based stats. Identities = 98/393 (24%), Positives = 167/393 (42%), Gaps = 18/393 (4%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGV 153 L EQ + E F + + D E L++ G G+ +P+ +GG Sbjct: 4 LTPEQRTLQTQARELAQSVFA--STAVQTDLTEQYPWDNVAQLRDAGFMGMMLPTSVGGR 61 Query: 154 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 GL ++E + +G I +G++ Q + + +G+ A Sbjct: 62 GLSTLDTVIVIEEMAKACATMGRITVDSNLGAIGAITKYGSEEQIKLAADLVLAGDK-PA 120 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 C++EP++GS A+ + T A G +Y LNG K WI+ GG++ + +FA+ Sbjct: 121 ICISEPNAGSAASEMTTRA--DKNGDHYILNGEKYWITGGGVSKLHLIFARVFDD----- 173 Query: 274 AVKEKITAFVV---ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL---GEVG 327 V++ I AF+ + G G+ G MG++ + F +++ ++ + Sbjct: 174 GVEQGIGAFITVLDDHGPEGLKVGRRLYAMGVRGIPETHLEFHDLKIHKSMMITFPDGLK 233 Query: 328 SGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMV 387 GF M N R G A G + + V + R QFG + F +Q +A M Sbjct: 234 RGFAALMSAYNAQRVGAGAVALGIAQCAFEEGVAYLKRREQFGRPLAEFQGLQWMVADMS 293 Query: 388 MLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPG 447 + M + + + +AA +KIF +E A KVT++ +Q G G+ + Sbjct: 294 VQLEAARLMLRSAAVSGET--FPDINKAAQAKIFAAETANKVTNDALQFFGSSGYGRHNP 351 Query: 448 VERVLRDLRIFRIFEGTNDILRLFVALQGCMDK 480 +ER +RD R+F I GT ILR VA + K Sbjct: 352 MERHVRDARMFTIAGGTAQILRTQVASKILDMK 384 >4HR3-A nrPDB Length = 415 Score = 295 bits (755), Expect = 4e-80, Method: Composition-based stats. Identities = 100/417 (23%), Positives = 164/417 (39%), Gaps = 29/417 (6%) Query: 91 PSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEE-------------------- 130 P ++ + EL+ V F + P + L +E Sbjct: 2 PGSMDFAPSARAAELIAAVREFIDAEVMPVERAVLAHHDELLGARAGTTAELWHVPPELD 61 Query: 131 TTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGIT-LGAHQSIGFKGI 189 + + G + L +P G GL N++YA L E +G + A S + + Sbjct: 62 SLKAKARAAGLWNLFLPDPELGGGLSNSEYAPLAEQMGRSLFAPTVFNCNAPDSGNMEVL 121 Query: 190 LLFGTKAQKEKYLPKLASGETVAAFCLTEPS-SGSDAASIRTSAVPSPCGKYYTLNGSKL 248 +G++ QKE +L L G+ +AFC+TEP + SDA ++ +AV G +NG K Sbjct: 122 HRYGSQEQKEVWLEPLLEGDIRSAFCMTEPDVASSDATNMAATAVVE--GDEVVINGRKW 179 Query: 249 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGI--KASN 306 W + G D + +TDP + + +V GIT MG + Sbjct: 180 WSTGVGHPDCKVII-FMGLTDPNA-HRYARHSMVLVPMDTPGITVERMLPTMGFYDEPGG 237 Query: 307 TAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNR 366 V FD VR+P++ + G GF++A L GR A L G + A +R Sbjct: 238 HGVVSFDNVRLPADAFIAGPGKGFEIAQGRLGPGRVHHAMRLIGLAEVALEHACRRGLDR 297 Query: 367 TQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ-GATDFQIEAAISKIFGSEA 425 T FG+ + N G +E++A + T + + +D G + K+ Sbjct: 298 TAFGKPLVNLGGNRERIADARIAINQTRLLVLHAAWLLDTVGIMGALSAVSEIKVAAPNM 357 Query: 426 AWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGK 482 A +V D IQI GG G + + + R R+ +G +++ R VA Sbjct: 358 AQQVIDMAIQIHGGGGLSNDFPLAAAWVNARALRLADGPDEVHRGVVARIELAKYAN 414 >2FON-A nrPDB Length = 683 Score = 286 bits (731), Expect = 3e-77, Method: Composition-based stats. Identities = 88/449 (19%), Positives = 162/449 (36%), Gaps = 66/449 (14%) Query: 181 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY 240 H + I GT Q+EK+LP + + + TE GS+ + T+A P Sbjct: 121 HWGMFIPAIKGQGTDKQQEKWLPLAYKMQIIGCYAQTELGHGSNVQGLETTATFDPQTDE 180 Query: 241 YTLN-----GSKLWISN-GGLADIFTVFAKTPVTDPATGAVKEKITAFVV-------ERG 287 + ++ SK W G ++ V+A+ G + F+V + Sbjct: 181 FVIHSPTLTSSKWWPGGLGKVSTHAVVYARLITDGKDYG-----VNGFIVQLRSLEDHKP 235 Query: 288 FGGITHGPPEKKMGIKASNTAE---VFFDGVRVPSENVLGEVGSGFK------------V 332 G+T G K G A N+ + + FD VR+P + +L V K + Sbjct: 236 LPGVTVGDIGMKFGNGAYNSMDNGVLSFDHVRIPRDQMLMRVSQVTKEGKYVQSDIPRQL 295 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFG-------EKIHNFGLIQEK--- 382 + R + A + M + A ++ R QFG ++ ++ Q + Sbjct: 296 LYGTMVYVRQSIVADASLAMSRAVCIATRYSAVRRQFGSQNGGQETQVIDYKTQQNRLFP 355 Query: 383 -LARMVMLQYVTESMAYMVSANMDQGA-------TDFQIEAAISKIFGSEAAWKVTDECI 434 LA ++V E + ++ + + A + A K + A +EC Sbjct: 356 LLASAYAFRFVGEWLKWLYTDVTQRLAANDFSTLPEAHACTAGLKSLTTSATADGIEECR 415 Query: 435 QIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNP 494 ++ GG G++ G+ + +EG N +L+L VA K +S LG+ K P Sbjct: 416 KLCGGHGYLCSSGLPELFAVYVPACTYEGDNVVLQLQVARFLM----KTISQLGTG-KKP 470 Query: 495 FGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVE--AKLI 552 G +G ++ R+ + + P R+ + +K Sbjct: 471 VGTVS-YMGRIEHLMQCRSDVKQA---EDWLKPSAVLEA-FEARSARMSVACAKNLSKFE 525 Query: 553 KHKKGIVNEQFLLQRLADGAIDLYAMVVV 581 ++G L L + A+ ++VV Sbjct: 526 NQEEGFA---ELAADLVEAAVAHCQLIVV 551 >5Y9D-A nrPDB Length = 709 Score = 268 bits (686), Expect = 4e-72, Method: Composition-based stats. Identities = 100/495 (20%), Positives = 173/495 (34%), Gaps = 81/495 (16%) Query: 96 EEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGL 155 EE+TQ +++++ + R + D +++ Q ++ + A + ++ + L Sbjct: 55 EEETQIVEKIMSSIER---DPVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSL 111 Query: 156 CNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPK--LASGETVAA 213 ++ GM D+ L H ++ I GT Q + ++ K +A + Sbjct: 112 WR------AQLHGMVDMSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGC 165 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLN-----GSKLWISNGGL-ADIFTVFAKTPV 267 F +TE GS+ + T+A + +N +K WI + FAK V Sbjct: 166 FAMTELGHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFAKLIV 225 Query: 268 TDPATGAVKEKITAFVVE-RGFG------GITHGPPEKKMGIKASNTAEVFFDGVRVPSE 320 G FVV R G++ G KKMG + + F VR+P + Sbjct: 226 HGKDYGTRN-----FVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQFTNVRIPRQ 280 Query: 321 NVLGE------VGSGFKVAMHILNNG-----RFGMAAALAGTMRGIIAKAVDHATNRTQF 369 N+L G K A+ L G R M A + + A+ +A R QF Sbjct: 281 NMLMRYAKVSDTGVVTKPALDQLTYGALIRGRVSMIADSFHVSKRFLTIALRYACVRRQF 340 Query: 370 GE-------KIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ---------------- 406 G KI ++ Q +L ++ Y + A + Sbjct: 341 GTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADEAQKTWIETTDRILALNPNDPAQK 400 Query: 407 --------GATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIF 458 + +A K F + K+ DEC Q GG G+ G + D + Sbjct: 401 NDLEKAVTDTKELFAASAGMKAFTTWGCAKIIDECRQACGGHGYSGYNGFGQGYADWVVQ 460 Query: 459 RIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSG 518 +EG N++L L + + L+G G + +G+ K + G G Sbjct: 461 CTWEGDNNVLCLSMGRGLVQSALQILAG------KHVGASIQYVGDKSKISQN----GQG 510 Query: 519 LSLSGLVHPELSRSG 533 L+ PE Sbjct: 511 TPREQLLSPEFLVEA 525 >4RM7-A nrPDB Length = 391 Score = 264 bits (675), Expect = 7e-71, Method: Composition-based stats. Identities = 91/391 (23%), Positives = 165/391 (42%), Gaps = 17/391 (4%) Query: 98 QTQFLKELVEPVSRFFEEVNDPA---KNDALEMVEETTWQGLKELGAFGLQVPSELGGVG 154 ++ + L+ V + E+ PA K + + + + +L G V Sbjct: 8 LSRDEQRLLNHVREYGEKYFTPASISKWRKDQGLPDEVVKAFVDLDFNGFGVIHRRNHRT 67 Query: 155 LCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGIL-LFGTKAQKEKYLPKLA-SGETVA 212 ++E + L + IL F + AQ + + +G Sbjct: 68 YDLFAQVLVIEELSRISGAC---LPFQNDLLQLQILEAFASSAQTSPFRTEYQDTGRLSY 124 Query: 213 AFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPAT 272 A ++EP +GSD S+RT G +NG+K++++NG A V A D Sbjct: 125 ALAISEPEAGSDTRSMRTHVTRE--GDTLVMNGTKMFVNNGEYAPALLVSAYDKTGDDG- 181 Query: 273 GAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKV 332 + + + ++V R GI PE+K+G A V FD V V L GF Sbjct: 182 ---EPEFSFWMVPRSAAGIYA-YPEQKIGQSMLPFATVRFDNVEVKESWRLKGSSKGFSQ 237 Query: 333 AMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYV 392 +L GR AA G + + AV A R FG++I + +Q KL M + Sbjct: 238 LYSLLEYGRVFTCAAALGEAQAAMEDAVAWARGREAFGQRIADLQQVQMKLTEMEVKLTN 297 Query: 393 TESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452 ++ Y + D+G ++ A+ K + +AA +V + +QI+GG G+++E V + Sbjct: 298 MRNLVYGAAREYDRGEHK-RLSVALMKYYVPKAATEVASDAMQILGGRGYIQENRVSSIW 356 Query: 453 RDLRIFRIFEGTNDILRLFVALQGCMDKGKE 483 +D R ++ +GT++++ + +A +++ K Sbjct: 357 QDCRGYQFADGTDEVM-VVIAAPLILEQYKA 386 >5YS9-A nrPDB Length = 708 Score = 261 bits (666), Expect = 9e-70, Method: Composition-based stats. Identities = 111/514 (21%), Positives = 174/514 (33%), Gaps = 79/514 (15%) Query: 96 EEQTQFLKELVEPVSRFFEEVNDPAKN---DALEMVEETTWQGLKELGAFGLQVPSELGG 152 EE ++ L+ + R DP N D E+ + + A + Sbjct: 49 EENVTMIERLMTELER------DPVLNVSGDYDMPKEQLRETAVARIAALSGHWKKDTEK 102 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGET-- 210 L ++ G+ D+G I LG H + I GTK Q + ++ K A+ Sbjct: 103 EALLR------SQLHGIVDMGTRIRLGVHTGLFMGAIRGSGTKEQYDYWVRKGAADVKGF 156 Query: 211 VAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLN-----GSKLWISNGGL-ADIFTVFAK 264 F +TE GS+ A + T+A + +N +K WI A FA+ Sbjct: 157 YGCFAMTELGHGSNVAGLETTATYIQDTDEFIINTPNTGATKWWIGGAAHSATHTACFAR 216 Query: 265 TPVTDPATGAVKEKITAFVV--ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENV 322 V G + V GI G KKMG A + + F VR+P +N+ Sbjct: 217 LLVDGKDYGVKIFVVQLRDVSSHSLMPGIALGDIGKKMGRDAIDNGWIQFTNVRIPRQNM 276 Query: 323 LGE------VGSGFKVAMHILNNG-----RFGMAAALAGTMRGIIAKAVDHATNRTQFGE 371 L + G + + L G R M A + I A+ +A R QFG Sbjct: 277 LMKYAKVSSTGKVSQPPLAQLTYGALIGGRVTMIADSFFVSQRFITIALRYACVRRQFGT 336 Query: 372 -------KIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGA---------------- 408 KI ++ Q +L ++ Y + A DQ Sbjct: 337 TPGQPETKIIDYPYHQRRLLPLLAFTYAMKMAADQSQIQYDQTTDLLQTIDPKDKGALGK 396 Query: 409 -----TDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEG 463 + +A K F + + D+C Q GG G+ G + D + +EG Sbjct: 397 AIVDLKELFASSAGLKAFTTWTCANIIDQCRQACGGHGYSGYNGFGQAYADWVVQCTWEG 456 Query: 464 TNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSG 523 N++L L M +G S LG P G++ L G + + LS Sbjct: 457 DNNVLCL------SMGRGLIQSCLGHRKGKPLGSSVGYLANKGLE-------QATLSGRD 503 Query: 524 LVHPELSRSGELAVRALEQFATVVEAKLIKHKKG 557 L P++ V K ++ KG Sbjct: 504 LKDPKVLIEAWEKVAN--GAIQRATDKFVELTKG 535 >4ZYJ-A nrPDB Length = 425 Score = 259 bits (662), Expect = 3e-69, Method: Composition-based stats. Identities = 85/402 (21%), Positives = 151/402 (37%), Gaps = 36/402 (8%) Query: 81 QLTTDQVFPYPSVLN-----EEQTQFLKELVEPVSRFFEEVNDPAK-NDALEMVEETTWQ 134 +T V +P VL E +T + L++ + R+ + ++ ND + + Sbjct: 20 HMTKPSVHEHPGVLADNGLCEPKTPAGRRLLDLLERYLPALEAESRDNDREATLPVHLFD 79 Query: 135 GLKELGAFGLQVPSELGGVGLCNTQY-ARLVEIVGMHDLGVGITLGAHQSIGFKG--ILL 191 +++ G G VP +LGG+G+ + A + + D GV + L S G Sbjct: 80 RMRKEGVLGATVPEDLGGLGVHSLHDVALALARIAGRDAGVALALHMQFSRGLTLDFEWR 139 Query: 192 FG---TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKL 248 G T+ E L ++ +GE V + D T+ + Y LNG K Sbjct: 140 HGAPSTRPLAEDLLRQMGAGEAVIC------GAVKDVRG--TTVLTRATDGSYRLNGRKT 191 Query: 249 WISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTA 308 +S G+A + V + ++ A VV R G+T MG+++S + Sbjct: 192 LVSMAGIATHYVVSTRL-----EEAGAPVRLAAPVVARTTPGLTVLDNWDGMGMRSSGSV 246 Query: 309 EVFFDGVRVPSENVL--GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNR 366 ++ FDG V + VL GE G A+ M G A+ R Sbjct: 247 DIVFDGCPVDRDRVLPRGEPGVRDDAALAGQTVSSIAMLGIYVGIAEAARRIAL--TELR 304 Query: 367 TQFGEKIHNFGLIQEKLARMVMLQYV-------TESMAYMVSANMDQGATDFQIEAAISK 419 + G + E AR+ L + +A +S ++ +K Sbjct: 305 RRGGAPAGVRTTVAEIDARLFALHTAVASALTTADRLADDLSGDLAARGRAMMTPFQYAK 364 Query: 420 IFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIF 461 + + + V D+C+ ++GG G+ + R+ RD+R Sbjct: 365 LLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRAGGFM 406 >4X28-A nrPDB Length = 400 Score = 259 bits (661), Expect = 3e-69, Method: Composition-based stats. Identities = 91/403 (22%), Positives = 170/403 (42%), Gaps = 37/403 (9%) Query: 98 QTQFLKELVEPVSRFFEEVNDPAKNDALEMVE---------ETTWQGLKELGAFGLQVPS 148 T +EL + +F + P + +AL V+ T + G L P Sbjct: 5 YTPQQEELRRELRSYFATLMTPERREALSSVQGEYGVGNVYRETIAQMGRDGWLALGWPK 64 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 208 E GG G + + G + S+ I+ +GT QK +LP++A+G Sbjct: 65 EYGGQGRSAMDQLIFTDEAAI--AGAPVPFLTINSVA-PTIMAYGTDEQKRFFLPRIAAG 121 Query: 209 ETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVT 268 + + +EP +G+D A++RT+AV G Y +NG K+W S AD + A Sbjct: 122 DLHFSIGYSEPGAGTDLANLRTTAVRD--GDDYVVNGQKMWTSLIQYAD-YVWLAVRTNP 178 Query: 269 DPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 328 + + I+ +V G + P + +T+ ++ VRVP N +GE + Sbjct: 179 ESSGAKKHRGISVLIVPTTAEGFSWTPVHT---MAGPDTSATYYSDVRVPVANRVGEENA 235 Query: 329 GFKVAMHILNNGRFGMA--AALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM 386 G+K+ + LN+ R + A + G +R + A + G ++ + +Q LAR+ Sbjct: 236 GWKLVTNQLNHERVALVSPAPIFGCLREVREWAQ---NTKDAGGTRLIDSEWVQLNLARV 292 Query: 387 VMLQYVTESMAYMVS----ANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGF 442 V + + + ++ D G + +A+ +K+FG+E A + ++++G Sbjct: 293 HAKAEVLKLINWELASSQSGPKDAGPSP--ADASAAKVFGTELATEAYRLLMEVLGTAAT 350 Query: 443 MKEP--------GVERVLRDLRIFRIFEGTNDILRLFVALQGC 477 +++ VER+ R I GTN++ R + + Sbjct: 351 LRQNSPGALLRGRVERMHRACLILTFGGGTNEVQRDIIGMVAL 393 >1R2J-A nrPDB Length = 366 Score = 249 bits (636), Expect = 3e-66, Method: Composition-based stats. Identities = 84/360 (23%), Positives = 145/360 (40%), Gaps = 14/360 (3%) Query: 119 PAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITL 178 A+ D + L G +V +E GG+GL + + VG + + Sbjct: 16 AAEWDTSGELPRDLLVRLGADGLLCAEVAAEHGGLGLGSRENGEFTAHVGSLCSSLRSVM 75 Query: 179 GAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCG 238 + + + G Q+ +L +L SG +AA +E +GSD +++RT G Sbjct: 76 TSQ-GMAAWTVQRLGDAGQRATFLKELTSG-KLAAVGFSERQAGSDLSAMRTRVRLD--G 131 Query: 239 KYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEK 298 ++G K+W + AD VF A VV G+ K Sbjct: 132 DTAVVDGHKVWTTAAAYADHLVVFGLQEDGSGA---------VVVVPADTPGVRVERVPK 182 Query: 299 KMGIKASNTAEVFFDGVRVPSENVLGEVGSGFK-VAMHILNNGRFGMAAALAGTMRGIIA 357 G +A+ A++ D VRVP+ VL G+ + L GR +A G +R Sbjct: 183 PSGCRAAGHADLHLDQVRVPAGAVLAGSGASLPMLVAASLAYGRKSVAWGCVGILRACRT 242 Query: 358 KAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAI 417 AV HA R QFG + + L+ +A + + + + S + D+G+ + + Sbjct: 243 AAVAHARTREQFGRPLGDHQLVAGHIADLWTAEQIAARVCEYASDHWDEGSPEMVPATIL 302 Query: 418 SKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGC 477 +K +E A Q++ G + VER RD ++ I EG++++ R+ +A Sbjct: 303 AKHVAAERAAAGAATAAQVLASAGAREGHVVERAYRDAKLMEIIEGSSEMCRVMLAQHAL 362 >3M9V-A nrPDB Length = 439 Score = 240 bits (611), Expect = 2e-63, Method: Composition-based stats. Identities = 79/386 (20%), Positives = 151/386 (39%), Gaps = 29/386 (7%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEV-NDPAKNDALEMVEETTWQGLKELGAFGLQVPSELG 151 L T + L++ ++ + + A++D T+ L++ G G VP+ELG Sbjct: 15 GLYAPVTPAGRVLLDRLAAHLPRIRSTAAEHDRDGTFPTDTFDALRKDGLMGATVPAELG 74 Query: 152 GVGLCNT-QYARLVEIVGMHDLGVGITLGAHQSIGF--KGILLFGTK---AQKEKYLPKL 205 G+G+ A + V D + L S G G + E+ L + Sbjct: 75 GLGVDRLYDVAVALLAVARADASTALALHMQLSRGLTLGYEWRHGDERARTLAERILRGM 134 Query: 206 ASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKT 265 +G+ V S D + T+ P G + L+G K +S + F + A+T Sbjct: 135 VAGDAVVC------SGIKDHHTAVTTLRPDGAGG-WLLSGRKTLVSMAPVGTHFVINART 187 Query: 266 PVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLG- 324 TD ++ + VV R G T +G++AS T ++ FD +P+++VL Sbjct: 188 DGTDG-----PPRLASPVVTRDTPGFTVLDNWDGLGMRASGTVDIVFDDCPIPADHVLMR 242 Query: 325 -EVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKL 383 VG+ + + G + AV A R + L+ E Sbjct: 243 DPVGARNDAVLAGQTVSSVSVLGVYVGVAQAAYDTAVA-ALERRPEPPQAAALTLVAEID 301 Query: 384 ARMVML-------QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQI 436 +R+ L ++++ +S +MD+ +K+ + A ++ +C+ + Sbjct: 302 SRLYALRATAGSALTAADALSADLSGDMDERGRQMMRHFQCAKLAVNRLAPEIVSDCLSL 361 Query: 437 MGGMGFMKEPGVERVLRDLRIFRIFE 462 +GG + + R+LRD++ R + Sbjct: 362 VGGASYTAGHPLARLLRDVQAGRFMQ 387 >4Y9J-A nrPDB Length = 593 Score = 239 bits (609), Expect = 4e-63, Method: Composition-based stats. Identities = 82/332 (24%), Positives = 141/332 (42%), Gaps = 23/332 (6%) Query: 186 FKGILLFGTKAQKEKYLPKLASGETVAAFC----LTEPSSGSDAASIRTSAVPSPCGKYY 241 + L+G + + +L S + A+ +TE GSD A + Y Sbjct: 156 LTSLNLYGKHKLATEAVDRLRSRDPSKAWTSGQWMTEKKGGSDVAGGCDTYAVQIDKDTY 215 Query: 242 TLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVE-----RGFGGITHGPP 296 L+G K W S+ AD+ A+ +D ++ F+++ GI Sbjct: 216 RLHGYK-WFSSAVDADVALTLARIVDSDGNALEGSRGLSLFLLKIRDESGNLNGIQMVRL 274 Query: 297 EKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGII 356 + K+G K TAE+ DG +G+ G G ++LN R A A G MR II Sbjct: 275 KNKLGTKQLPTAELLLDGAI---AERIGDQGRGVAGISNMLNITRIHNAVASLGYMRRII 331 Query: 357 AKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANM---------DQG 407 + A D++T R FG+ + L LA+M + + + + + + D Sbjct: 332 SLARDYSTKRVVFGQTQSKWPLHTTTLAKMEVDTRGSMLLLFEAARLLGLSEAGKSSDVE 391 Query: 408 ATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDI 467 A ++ + K++ + A + E I+ GG G+M++ G+ +LRD ++ I+EGT ++ Sbjct: 392 AMMLRLITPVLKLYAGKQAVPMVSEGIECFGGQGYMEDTGLPTLLRDAQVTPIWEGTTNV 451 Query: 468 LRLFVALQGCMDKGKELSGLGSALKNPFGNAG 499 L L V L+ K L G ++ GN Sbjct: 452 LSLDV-LRVFSGKENILLAFGKRVEQLLGNTK 482 >5GJ7-A nrPDB Length = 398 Score = 236 bits (602), Expect = 2e-62, Method: Composition-based stats. Identities = 73/378 (19%), Positives = 137/378 (36%), Gaps = 27/378 (7%) Query: 91 PSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSEL 150 + L + + L+ + F E ++D + LK G VP E Sbjct: 10 EAALPADVRERLRITRDLAQAFHERA---PEHDRAGDFPFENIEDLKASGYVRWTVPVEY 66 Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGIL--LFGTKAQKEKYLPKLASG 208 GG+GL + E++ D + +G H I F + + + G Sbjct: 67 GGLGLSLEEMLMHQEVLAKGDGSTALAIGWHVGILLHLRETGAFPDELFRMVCESVVKEG 126 Query: 209 ETVAAFCLTEPSSGSDAAS--IRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTP 266 + + C TEP++GS + T+AV P G Y + G K + + V A Sbjct: 127 ALINS-CATEPATGSPSRGGKPETTAVKVPGG--YRITGRKTFSTLSPALTWIMVTATVA 183 Query: 267 VTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEV 326 D + F+V + + +G++A+ + ++ V VP E V+ Sbjct: 184 DED--------VVGQFLVRK--EDVEIVETWDTLGMRATGSHDIVLKDVFVPEERVIVIQ 233 Query: 327 GSGFKVAMHILNNGR-FGMAAALAGTMRGIIAKAVDHATNRT--QFGEKIHNFGLIQEKL 383 G + +G + A G A+++A I +++KL Sbjct: 234 RPGVQAERRPDGSGWLLHIPACYLGIALAARDFALEYAATYRPNTLPHPIAEVPHVEQKL 293 Query: 384 ARMVMLQYVTESMAYMVSANMDQGATD----FQIEAAISKIFGSEAAWKVTDECIQIMGG 439 M + ++ Y ++ D + + Q + K + AA +V D ++++GG Sbjct: 294 GEMELKLLAARTLLYDLARRFDAASPEERVKLQPQFGAVKTLATNAANQVVDLAMRVVGG 353 Query: 440 MGFMKEPGVERVLRDLRI 457 + +ER RD+R Sbjct: 354 RSLSRALPLERYYRDVRA 371 >3MKH-A nrPDB Length = 438 Score = 231 bits (588), Expect = 1e-60, Method: Composition-based stats. Identities = 84/400 (21%), Positives = 145/400 (36%), Gaps = 36/400 (9%) Query: 102 LKELVEPVSRFFEEVNDPAKNDALEMVEETTWQ---------GLKELGAFGLQVPSELGG 152 K + + PA+ L+ + + G Q+ GG Sbjct: 11 QKGTYQAARSLARNLLMPARQTYLQHPPNSPLRFQSTQPTYAAAVSAGILKGQISPAHGG 70 Query: 153 VGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE--T 210 G + A LVE + +T+ A +G I L Q ++L SGE Sbjct: 71 TGGTLIESAILVEECYSVEPSAALTIFA-TGLGLTPINL-AAGPQHAEFLAPFLSGEGSP 128 Query: 211 VAAFCLTEPSSGSDA-----ASIRTSAVPSPCGKYYTLNGSKLWISNGGL-----ADIFT 260 +A+ +EP ++A +T+A G + +NG K+W +N D+ Sbjct: 129 LASLVFSEPGGVANALEKGAPGFQTTARLE--GDEWVINGEKMWATNCAGWDFKGCDLAC 186 Query: 261 VFAKTPVT------DPATGAVKEKITAFVVERGFGG-ITHGPPEKKMGIKASNTAEVFFD 313 V + T DP + +T ++R G G + + V + Sbjct: 187 VVCRDATTPLEEGQDPENKVMIILVTRADLDRNGEGSFEVLRHVATPGHTSVSGPHVRYT 246 Query: 314 GVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGE-K 372 VRVP++NVL G G KVA + + A G MR A+ A + G Sbjct: 247 NVRVPTKNVLCPAGQGAKVAFGAFDGSAVLVGAMGVGLMRAAFDAALKFAKEDNRGGAVP 306 Query: 373 IHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIE---AAISKIFGSEAAWKV 429 + + L+ + + ++ + + M+ G D+ A +K+F SEAA K Sbjct: 307 LLERQAFADLLSGVKIQTEAARALTWKAAHAMENGPGDYDARRELALAAKVFCSEAAVKA 366 Query: 430 TDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILR 469 + I +G + + +L + IF+G N +R Sbjct: 367 CTDVINAVGISAYDLQRPFSDLLNTAVVLPIFDGGNVGIR 406 >2C12-A nrPDB Length = 439 Score = 227 bits (578), Expect = 1e-59, Method: Composition-based stats. Identities = 89/417 (21%), Positives = 165/417 (39%), Gaps = 48/417 (11%) Query: 93 VLNEEQTQFLKELVEPVSRFFEEVNDPA------KNDALEMVE--ETTWQGLKELGAFGL 144 +++ + + E F V A + D L + ++ G Sbjct: 1 MVDFKLSPSQLEARRHAQAFANTVLTKASAEYSTQKDQLSRFQATRPFYREAVRHGLIKA 60 Query: 145 QVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPK 204 QVP LGG + ++E + + IT+ A ++G ++L + + +EK+L Sbjct: 61 QVPIPLGGTMESLVHESIILEELFAVEPATSITIVA-TALGLMPVILCDSPSLQEKFLKP 119 Query: 205 LASGE--TVAAFCLTEPSSGSD-----AASIRTSAVPSPCGKYYTLNGSKLWISNGGL-- 255 SGE +A+ +EP+ ++ ++T+A G + ++G KLW SN G Sbjct: 120 FISGEGEPLASLMHSEPNGTANWLQKGGPGLQTTARKV--GNEWVISGEKLWPSNSGGWD 177 Query: 256 ---ADIFTVFAKTPVT---------DPATGAVKEKITAFVVERGFGGIT--HGPPEKKMG 301 AD+ V + DPAT +T + G PE Sbjct: 178 YKGADLACVVCRVSDDPSKPQDPNVDPATQIAVLLVTRETIANNKKDAYQILGEPELAGH 237 Query: 302 IKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTM-----RGII 356 I S F VP EN+L G + L F M+AAL G M R Sbjct: 238 ITTSG-PHTRFTEFHVPHENLLCTPG----LKAQGLVETAFAMSAALVGAMAIGTARAAF 292 Query: 357 AKAVDHATNRTQFGEK-IHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIE- 414 +A+ A + T+ G K I + +KL + + + + ++ A +++++ Sbjct: 293 EEALVFAKSDTRGGSKHIIEHQSVADKLIDCKIRLETSRLLVWKAVTTLEDEALEWKVKL 352 Query: 415 --AAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILR 469 A +KI+ ++ A + + ++ +G + K+ R+L ++ + +F+G N LR Sbjct: 353 EMAMQTKIYTTDVAVECVIDAMKAVGMKSYAKDMSFPRLLNEVMCYPLFDGGNIGLR 409 >3U33-A nrPDB Length = 541 Score = 223 bits (567), Expect = 3e-58, Method: Composition-based stats. Identities = 73/345 (21%), Positives = 137/345 (39%), Gaps = 21/345 (6%) Query: 194 TKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNG 253 + LP + +TE GSD S T A G Y L G K + S Sbjct: 162 SDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDG-SYRLVGHKWFFS-V 219 Query: 254 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFD 313 +D V A+T A G + F+ + I + K+G +++ + EV F Sbjct: 220 PQSDAHLVLAQT-----AGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQ 274 Query: 314 GVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKI 373 +LG G G ++ + + RF A MR + A+ HA R FG + Sbjct: 275 DAI---GWLLGLEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPL 331 Query: 374 HNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTD-- 431 L++ L+RM + ++ + ++ D+ A EA +++F A + + Sbjct: 332 IQQPLMRHVLSRMALQLEGQTALLFRLARAWDRRADA--KEALWARLFTPAAKFVICKRG 389 Query: 432 -----ECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSG 486 E ++++GG+G+ +E + R+ R++ + I+EG+ +I+ L V ++K + Sbjct: 390 MPFVAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLR--VLNKQAGVYD 447 Query: 487 LGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSR 531 L S A ++L+++ + + H Sbjct: 448 LLSEAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLL 492 >3MXL-A nrPDB Length = 395 Score = 219 bits (558), Expect = 3e-57, Method: Composition-based stats. Identities = 85/388 (21%), Positives = 143/388 (36%), Gaps = 31/388 (7%) Query: 92 SVLNEEQTQFLKELVEPVSRFFEEVNDPA-KNDALEMVEETTWQGLKELGAFGLQVPSEL 150 + L T + +V+ ++ ++ A D ++ +LG G VP+EL Sbjct: 3 ADLRAPLTPAGRTVVDLLAGVIPRISAEAADRDRTGTFPVEAFEQFAKLGLMGATVPAEL 62 Query: 151 GGVGLCNT-QYARLVEIVGMHDLGVGITLGAHQSIGFKGIL--LFGTK---AQKEKYLPK 204 GG+GL A + + D + S G GT A E+ L Sbjct: 63 GGLGLTRLYDVATALMRLAEADASTALAWHVQLSRGLTLTYEWQHGTPPVRAMAERLLRA 122 Query: 205 LASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAK 264 +A GE L DA + T G + L+G K+ +S +A F V A+ Sbjct: 123 MAEGEAAVCGAL------KDAPGVVTELHSDGAGG-WLLSGRKVLVSMAPIATHFFVHAQ 175 Query: 265 TPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL- 323 D + + VV R G+T +G++AS T EV FD V ++ +L Sbjct: 176 RRDDDGS-----VFLAVPVVHRDAPGLTVLDNWDGLGMRASGTLEVVFDRCPVRADELLE 230 Query: 324 -GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEK-IHNFGLIQE 381 G VG+ + M AG + AV R GE L+ Sbjct: 231 RGPVGARRDAVLAGQTVSSITMLGIYAGIAQAARDIAVGFCAGR--GGEPRAGARALVAG 288 Query: 382 KLARMVML-------QYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECI 434 R+ L ++ + +S + D+ +K+ +E A V D+C+ Sbjct: 289 LDTRLYALRTTVGAALTNADAASVDLSGDPDERGRRMMTPFQYAKMTVNELAPAVVDDCL 348 Query: 435 QIMGGMGFMKEPGVERVLRDLRIFRIFE 462 ++GG+ + + R+ RD+R + Sbjct: 349 SLVGGLAYTAGHPLSRLYRDVRAGGFMQ 376 >5EZ3-A nrPDB Length = 573 Score = 213 bits (542), Expect = 2e-55, Method: Composition-based stats. Identities = 80/325 (24%), Positives = 142/325 (43%), Gaps = 30/325 (9%) Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 +TE G+D + T A P G + L G K ++S ++D F A+T Sbjct: 211 MGMTEKQGGTDVRANATRAEP-AIGGAWRLTGHKWFMS-APMSDAFLTLAQT-------- 260 Query: 274 AVKEKITAFVVER-----GFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGS 328 KE ++ F++ R G + K+G +++ ++EV FDG ++G G Sbjct: 261 --KEGLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGA---LGQMIGSPGE 315 Query: 329 GFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVM 388 G K M ++ R A A AG MR +A+AV H+ +R FG+ + L+Q LA M + Sbjct: 316 GVKTIMDMVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMAL 375 Query: 389 LQYVTESMAYMVSANMDQGATDFQIEAAIS-------KIFGSEAAWKVTDECIQIMGGMG 441 +++ ++ D A+D + EAA + K + + A + E ++ +GG G Sbjct: 376 DVAGATALSMRLARAFDMAASD-RAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNG 434 Query: 442 FMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKG--KELSGLGSALKNPFGNAG 499 ++++ + R R+ + I+EG+ +++ L VA + S P G Sbjct: 435 YIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGT 494 Query: 500 LLLGEAGKQLRRRAGLGSGLSLSGL 524 + + A QL + L L Sbjct: 495 IDVLRAALQLTETDQGVARLLTEQL 519 >4JEK-A nrPDB Length = 453 Score = 199 bits (505), Expect = 4e-51, Method: Composition-based stats. Identities = 70/370 (18%), Positives = 130/370 (35%), Gaps = 34/370 (9%) Query: 117 NDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGI 176 + D + L+ G L VP E GG G +V + D +G Sbjct: 69 ATAVERDRAGGSATAEREDLRASGLLSLLVPREYGGWGADWPTAIEVVREIAAADGSLGH 128 Query: 177 TLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSP 236 G H + I L G++ Q+E ++A +E + S + SA P+ Sbjct: 129 LFGYHLT-NAPMIELIGSQEQEEHLYTQIAQNNWWTGNASSE--NNSHVLDWKVSATPTE 185 Query: 237 CGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPP 296 G Y LNG+K + S +D+ VF P GA I A + G+T Sbjct: 186 DGG-YVLNGTKHFCSGAKGSDLLFVFGVVQDDSPQQGA----IIAAAIPTSRAGVTPNDD 240 Query: 297 EKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNG-------RFGMAAALA 349 +G++ +++ F V+V + VLG + F +A G + A Sbjct: 241 WAAIGMRQTDSGSTDFHNVKVEPDEVLGAPNA-FVLAFIQSERGSLFAPIAQLIFANVYL 299 Query: 350 GTMRGIIAKAVDHATNRTQFGEKIHNFGLI----------QEKLARMVMLQYVTESMAYM 399 G G + A ++ + + + +A + A++ Sbjct: 300 GIAHGALDAAREYTRTQARPWTPAGIQQATEDPYTIRSYGEFTIA-LQGADAAAREAAHL 358 Query: 400 VSANMDQG-------ATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVL 452 + D+G + ++ + K + AA ++ +++G G G +R Sbjct: 359 LQTVWDKGDALTPEDRGELMVKVSGVKALATNAALNISSGVFEVIGARGTHPRYGFDRFW 418 Query: 453 RDLRIFRIFE 462 R++R + + Sbjct: 419 RNVRTHSLHD 428 >4XVX-A nrPDB Length = 389 Score = 198 bits (504), Expect = 6e-51, Method: Composition-based stats. Identities = 76/359 (21%), Positives = 146/359 (40%), Gaps = 23/359 (6%) Query: 120 AKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGM----HDLGVG 175 A+ +A E + L G F + ++ +LVE+ G+G Sbjct: 30 AEAEAQERFPRQLIEHLGVCGVFDAKWATD------ARPDVGKLVELAFALGQLASAGIG 83 Query: 176 ITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPS 235 + + H S + FG + G V +E S GSD + T Sbjct: 84 VGVSLHDS-AIAILRRFGKSDYLRDICDQAIRGAAVLCIGASEESGGSDLQIVETEIRSR 142 Query: 236 PCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGP 295 G + + G K ++S +AD V A++ DP + + A ++ Sbjct: 143 DGG--FEVRGVKKFVSLSPIADHIMVVARSVDHDPTSRHGNVAVVA----VPAAQVSVQT 196 Query: 296 PEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGI 355 P +K+G +TA V D VP++ ++ G+G L + R +A +A + + Sbjct: 197 PYRKVGAGPLDTAAVCID-TWVPADALVARAGTGLAAISWGLAHERMSIAGQIAASCQRA 255 Query: 356 IAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEA 415 I + +R QFG+ + ++ ++A + + + Y + +QG + + A Sbjct: 256 IGITLARMMSRRQFGQTLFEHQALRLRMADLQARV---DLLRYALHGIAEQGRLELRTAA 312 Query: 416 AISKIFGSEAAWKVTDECIQIMGGMGFM-KEPGVERVLRDLRIFRIFEGTNDILRLFVA 473 A+ + + +V EC+ I GG G++ E + + RD+++ R+ GT+++L VA Sbjct: 313 AVK-VTAARLGEEVISECMHIFGGAGYLVDETTLGKWWRDMKLARVGGGTDEVLWELVA 370 >5XDD-A nrPDB Length = 414 Score = 196 bits (498), Expect = 3e-50, Method: Composition-based stats. Identities = 68/364 (18%), Positives = 126/364 (34%), Gaps = 30/364 (8%) Query: 121 KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGA 180 + + + ++ G L + E GG+G + + D +G G Sbjct: 34 ERERAGGTPKAERDAIRRSGLLTLLISKERGGLGESWPTVYEAIAEIASADASLGHLFGY 93 Query: 181 HQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKY 240 H S F + LF + QK ++ P+ +E ++ R +A P P G Sbjct: 94 HFS-NFAYVDLFASPEQKARWYPQAVRERWFLGNASSENNA--HVLDWRVTATPLPDG-S 149 Query: 241 YTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKM 300 Y +NG+K + S AD VFA T G +I A ++ G+ + Sbjct: 150 YEINGTKAFCSGSADADRLLVFAVTSRDPNGDG----RIVAALIPSDRAGVQVNGDWDSL 205 Query: 301 GIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILN------NGRFGMAAALAGTMRG 354 G++ +++ V F GV V + +LG G + G RG Sbjct: 206 GMRQTDSGSVTFSGVVVYPDELLGTPGQVTDAFASGSKPSLWTPITQLIFTHLYLGIARG 265 Query: 355 IIAKAVDHATNRT-----QFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMD---- 405 + +A ++ + + EK + V E+ A V+ + Sbjct: 266 ALEEAAHYSRSHSRPFTLAGVEKATEDPYVLAIYGEFAAQLQVAEAGAREVALRVQELWE 325 Query: 406 ------QGATDFQIEAAISKIFGSEAAWKVTDECIQIMGG-MGFMKEPGVERVLRDLRIF 458 + ++ A +KI + ++T + MG ++ G +R RD R Sbjct: 326 RNHVTPEQRGQLMVQVASAKIVATRLVIELTSRLYEAMGARAAASRQFGFDRFWRDARTH 385 Query: 459 RIFE 462 + + Sbjct: 386 TLHD 389 >1IS2-A nrPDB Length = 661 Score = 169 bits (428), Expect = 4e-42, Method: Composition-based stats. Identities = 87/469 (18%), Positives = 148/469 (31%), Gaps = 62/469 (13%) Query: 178 LGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPC 237 L H + +L T Q+E++ + E + TE G+ + T+A P Sbjct: 100 LDLHLGMFLPTLLHQATAEQQERFFMPAWNLEITGTYAQTEMGHGTHLRGLETTATYDPK 159 Query: 238 GKYYTLNGS-----KLWISN-GGLADIFTVFAKTPVTDPATGAVKEKITAFVVE------ 285 + + LN K W G ++ V A+ G + AFVV Sbjct: 160 TQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQLITQGECYG-----LHAFVVPIREIGT 214 Query: 286 -RGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLG------EVGSGFKVAMHILN 338 + GIT G K G + + + D R+P EN+L G+ K + L Sbjct: 215 HKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLT 274 Query: 339 NG-----RFGMAAALAGTMRGIIAKAVDHATNRTQ------FGEK-IHNFGLIQEK---- 382 G R + A ++ A+ ++ R Q E I +F Q K Sbjct: 275 YGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQILDFQTQQYKLFPL 334 Query: 383 LARMVMLQYVTESMAYMVSANMD-------QGATDFQIEAAISKIFGSEAAWKVTDECIQ 435 LA +V M + + A K F + A +EC Sbjct: 335 LATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTANAGIEECRM 394 Query: 436 IMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPF 495 GG G+ G+ + FEG N ++ L A + M ++ Sbjct: 395 ACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTA-RFLMKIYDQV-----RSGKLV 448 Query: 496 GNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAK--LIK 553 G L + Q + + ++ ++ + +RA + + Sbjct: 449 GGMVSYLNDLPSQRIQPQQVAVWPTMVD-INSLEGLTEAYKLRAARLVEIAAKNLQTHVS 507 Query: 554 HKKGIVNEQFLL-QRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKM 601 H+K L L + VVV + S+ P Q + + Sbjct: 508 HRKSKEVAWNLTSVDLVRASEAHCHYVVV-----KVFSDKLPKIQDKAV 551 >5K3G-A nrPDB Length = 684 Score = 156 bits (393), Expect = 4e-38, Method: Composition-based stats. Identities = 62/372 (16%), Positives = 120/372 (32%), Gaps = 53/372 (14%) Query: 175 GITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVP 234 G + H + + + Q+ K+L + E + + TE G++ ++ T+A Sbjct: 110 GNPMALHGVMFIPALNAQASDEQQAKWLIRALRREIIGTYAQTEMGHGTNLQNLETTATY 169 Query: 235 SPCGKYYTLN-----GSKLWISN-GGLADIFTVFAKTPVTDPATGAVKEKITAFVVE--- 285 + + L+ K W N G ++ V A + G F+V Sbjct: 170 DIGTQEFVLHTPKITALKWWPGNLGKSSNYAVVVAHMYIKGKNFGP-----HTFMVPLRD 224 Query: 286 ----RGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGE----VGSGF------- 330 + GIT G KM + + F+ R+P N+L G Sbjct: 225 EKTHKPLPGITIGDIGPKMAYNIVDNGFLGFNNYRIPRTNLLMRHTKVEADGTYIKPPHA 284 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGE--------KIHNFGLIQEK 382 K+ + + R M A + + A ++ R Q G+ K+ + Q + Sbjct: 285 KINYSAMVHVRSYMLTGQAIMLSYALNIATRYSAVRRQ-GQIDKNEPEVKVLEYQTQQHR 343 Query: 383 L----ARMVMLQYVTESMAYMVSANMDQGAT-------DFQIEAAISKIFGSEAAWKVTD 431 L AR Q+ + + + + D + K + + + Sbjct: 344 LFPFIARAYAFQFAGAETVKLYERVLKEMKSGNVSLMADLHALTSGLKSVVTHQTGEGIE 403 Query: 432 ECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSAL 491 + GG G+ + + +EG N ++ L +A K + + S Sbjct: 404 QARMACGGHGYSMASYISEIYGVAIGGCTYEGENMVMLLQLARYLV----KSAALVKSGK 459 Query: 492 KNPFGNAGLLLG 503 + G LG Sbjct: 460 ASQLGPLVAYLG 471 >5K3J-A nrPDB Length = 674 Score = 154 bits (388), Expect = 2e-37, Method: Composition-based stats. Identities = 75/456 (16%), Positives = 142/456 (31%), Gaps = 61/456 (13%) Query: 175 GITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVP 234 G H ++ + + Q+EK+L + E + + TE GS+ ++ T+AV Sbjct: 108 GHPFALHDALFIPTLQSQASDEQQEKWLERARRREIIGCYAQTELGHGSNLRNLETTAVY 167 Query: 235 SPCGKYYTLN-----GSKLWIS-NGGLADIFTVFAKTPVTDPATGAVKEKITAFVV---- 284 + + L+ K W G + V A+ + G F+V Sbjct: 168 DIASQEFVLHTPTTTALKWWPGALGKSCNYALVVAELIIKRNNYGP-----HFFMVQLRD 222 Query: 285 ---ERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGE----VGSGF------- 330 G+T G KM A++ + + +RVP N+L G Sbjct: 223 EKTHIPLKGVTVGDIGPKMNFNAADNGYLGLNNLRVPRTNLLMRHCKVEADGTYVKPPHA 282 Query: 331 KVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGE--------KIHNFGLIQEK 382 K+ + R MA + + A ++ R Q G K+ ++ Q + Sbjct: 283 KIGYSGMVKIRSQMAMEQGLFLAHALTIAARYSAVRRQ-GHLDDKQVEVKVLDYQTQQHR 341 Query: 383 ----LARMVMLQYVTESMAYMVSANMDQ-------GATDFQIEAAISKIFGSEAAWKVTD 431 LAR + ++ S + G D + K + + + Sbjct: 342 LFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVAHETGEGIE 401 Query: 432 ECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSAL 491 + GG G+ + V + G N ++ L +A K + + + Sbjct: 402 QARMACGGHGYSMASYISVVYGIAIGGCTYAGENMVMLLQLARYLV----KSVELIKAGK 457 Query: 492 KNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKL 551 G L + + + G + R A + E++ Sbjct: 458 AKKLGPVASYLADKSDETDLTSLNGYVKMFENMAR----RQAWKATEKFLKLMESGESRE 513 Query: 552 IKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASR 587 + K V L R + L+ + + R SR Sbjct: 514 VAWNKSAVE----LTRASRLHTRLFIIEAFMRRVSR 545 >4X28-D nrPDB Length = 373 Score = 142 bits (357), Expect = 5e-34, Method: Composition-based stats. Identities = 68/389 (17%), Positives = 127/389 (32%), Gaps = 34/389 (8%) Query: 95 NEEQTQFLKELVEPVSRFFEEVNDPAKNDALE-MVEETTWQGLKELGAFGLQVPSELGGV 153 E Q L LV+ + + D LE + W+ L + G P LGG Sbjct: 5 TTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGD 64 Query: 154 GLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAA 213 G + ++ +G V + + FG+ ++ + SG+ + Sbjct: 65 GFGVLEQVAVLVALGHQLAAVPYLESV--VLAAGALARFGSPELQQGWGVSAVSGDRILT 122 Query: 214 FCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATG 273 L + T G Y L G++ + G +AD F V A+T Sbjct: 123 VALDGEMGEGPVQAAGT-------GHGYRLTGTRTQVGYGPVADAFLVPAETDS------ 169 Query: 274 AVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVA 333 F+V G G+ G+ + E+ +G +V + +G G VA Sbjct: 170 ----GAAVFLVAAGDPGVAVT-ALATTGLGSVGHLEL--NGAKVDAARRVG----GTDVA 218 Query: 334 MHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVT 393 + + A G + + ++A R QF I +F + ++LA + Sbjct: 219 VWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGL 278 Query: 394 ESMAYMVSANMDQG-------ATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEP 446 + + + I+ A + + +EA +V + + GG+G + Sbjct: 279 RLTLTQAAWRVAEDSLASRECPQPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDH 338 Query: 447 GVERVLRDLRIFRIFEGTNDILRLFVALQ 475 V R + G + + Sbjct: 339 PVHRYFLAAKQTEFALGGATGQLRRIGRE 367 >2RFQ-A nrPDB Length = 394 Score = 99.4 bits (246), Expect = 4e-21, Method: Composition-based stats. Identities = 67/396 (16%), Positives = 131/396 (33%), Gaps = 65/396 (16%) Query: 95 NEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVG 154 + E Q L L+ + +E D + + + + + L+E G F L P + GG Sbjct: 9 SHEVMQRLDALLPTLRERAQETEDLRR------IPDDSMKALQETGFFRLLQPEQWGGYQ 62 Query: 155 LCNTQYARLVEIVGMHDLGVG---ITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETV 211 + V + G +G H + LF +AQ++ + Sbjct: 63 ADPVLFYSAVRKIASACGSTGWVSSIIGVHNWH----LALFSQQAQEDVW---------- 108 Query: 212 AAFCLTEPSSGSDAASIRTSAVPSPCG----KYYTLNGSKLWISNGGLADIFTVFAKTPV 267 + +D I +S P G YT+NG+ W S A +A Sbjct: 109 --------GNDTDVR-ISSSYAPMGAGQVVDGGYTVNGAWAWSSGCDHAS----WAVLGG 155 Query: 268 TDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLG--- 324 G + ++ F++ R +G++ + + V + V VP+ VL Sbjct: 156 PVIKDGRPVDFVS-FLIPR--EDYRIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKA 212 Query: 325 -----EVG-SGFKVAMHILNNGRFG---MAAALAGTMRGIIAKAVDH--ATNRTQF-GEK 372 G ++ + G ++A + G G V+H R F GEK Sbjct: 213 MSNLTAPGLERNTAPVYKMPWGTIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEK 272 Query: 373 IHNFGLIQEKLARMVMLQYVT-ESMAYMVSANM------DQGATDFQIEAAISKIFGSEA 425 + + ++A ++ V+ ++ + ++ A ++ + Sbjct: 273 AKDDPFAKVRIAEASSDIDAAWRQLSGNVADEYALLVAGEEVPFELRLRARRDQVRATGR 332 Query: 426 AWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIF 461 A D+ + G ++R RD R+ Sbjct: 333 AISSIDKLFESSGATALANGTPLQRFWRDAHAGRVH 368 >5LVW-A nrPDB Length = 413 Score = 96.7 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 63/394 (15%), Positives = 123/394 (31%), Gaps = 56/394 (14%) Query: 90 YPSVLNEEQTQFLKELVEPVSRFFEEVND-PAKNDALEMVEETTWQGLKELGAFGLQVPS 148 + + + E + ELVE V +F D A+ + + + T + + + L Sbjct: 16 HMTDIRSETAELRAELVERVHKFGPVFADGVAEGERERRLPDATVRAIDQSQLAMLWTAK 75 Query: 149 ELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASG 208 GG+ + + +++ + + + G+ K+ P+ A Sbjct: 76 SYGGLETDVRTMSEVAKVLSHYCPSTSWVVN----------NVNGSNLLASKF-PRAALD 124 Query: 209 ETVAAFCLTEPSS-GSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPV 267 E P + + + +AV +P G Y L GS + + D + A+ Sbjct: 125 EVFGDA----PGAKLASVFAAAGTAVRTPGG--YRLTGSWPYGTGILHDDWAILVAREVD 178 Query: 268 TDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVG 327 D G ++ V R +T +G++A+ + V VP V+ Sbjct: 179 AD---GEPVGGLSMLVPARD---LTVEDTWHTVGMRATGSHTVVLRDTFVPEHRVISGEL 232 Query: 328 SGFKVAMHILN-----------NGRFGMAAALAGTMRGIIAKAVDHATNR---------- 366 + + L A+ + G + A V+ A R Sbjct: 233 QRSRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQ 292 Query: 367 ---TQFGEKIHNFGLIQEKLARMVMLQYVTES--MAYMVSANMDQGATDFQIEAAISKIF 421 F + + A M + + T AY A D + + + Sbjct: 293 TDSRTFVSSLGR-TALSIDAAEMHVARAATALDDAAYDAVALPDSELLRIRGDVGQAVSL 351 Query: 422 GSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDL 455 + A DE + G F + ++R RD Sbjct: 352 VTTA----LDELLWAHGAASFAESNPLQRYWRDA 381 >3AFF-A nrPDB Length = 394 Score = 94.8 bits (234), Expect = 1e-19, Method: Composition-based stats. Identities = 63/394 (15%), Positives = 124/394 (31%), Gaps = 52/394 (13%) Query: 94 LNEEQTQFLKELVEPVSRFFEEVNDPAK-NDALEMVEETTWQGLKELGAFGLQVPSELGG 152 + Q + + ++ + E+ D A+ + L + + T + L ++G F L P + GG Sbjct: 1 MTSIQQRDAQSVLAAIDNLLPEIRDRAQATEDLRRLPDETVKALDDVGFFTLLQPQQWGG 60 Query: 153 VGLCNTQYARLVEIVGMHDLGVG---ITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGE 209 + + + G +G H + LF +AQ+E + ++ Sbjct: 61 LQCDPALFFEATRRLASVCGSTGWVSSIVGVHNWH----LALFDQRAQEEVWGEDPST-R 115 Query: 210 TVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTD 269 +++ P A G Y +NGS W S A V Sbjct: 116 ISSSYA---PMG----------AGVVVDGG-YLVNGSWNWSSGCDHASWTFV-----GGP 156 Query: 270 PATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL------ 323 +F++ R +G++ + + + V VP L Sbjct: 157 VIKDGRPVDFGSFLIPRSE--YEIKDVWYVVGLRGTGSNTLVVKDVFVPRHRFLSYKAMN 214 Query: 324 GEVGSGFK---VAMHILNNGRFG---MAAALAGTMRGIIAKAVDH--ATNRTQF-GEKIH 374 G ++ + G ++A + G G A V+H R F GEK Sbjct: 215 DHTAGGLATNSAPVYKMPWGTMHPTTISAPIVGMAYGAYAAHVEHQGKRVRAAFAGEKAK 274 Query: 375 NFGLIQEKLARMVMLQYVTESMA-------YMVSANMDQGATDFQIEAAISKIFGSEAAW 427 + + ++A Y + A + + + A ++ + + Sbjct: 275 DDPFAKVRIAEAASDIDAAWRQLIGNVSDEYALLAAGKEIPFELRARARRDQVRATGRSI 334 Query: 428 KVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIF 461 D + G E ++R RD R+ Sbjct: 335 ASIDRLFEASGATALSNEAPIQRFWRDAHAGRVH 368 >2JBS-A nrPDB Length = 422 Score = 85.5 bits (210), Expect = 7e-17, Method: Composition-based stats. Identities = 66/419 (15%), Positives = 130/419 (31%), Gaps = 57/419 (13%) Query: 89 PYPSVLNEEQTQFLK--ELVEPVSRFFEEVNDPAKN-DALEMVEETTWQGLKELGAFGLQ 145 P V QT + ++E + + ++ A++ + L V + + LKE+G Sbjct: 22 PIRLVYTHAQTPDVSGVSMLEKIQQILPQIAKNAESAEQLRRVPDENIKLLKEIGLHRAF 81 Query: 146 VPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYL--P 203 P GG+ + +A + + G + I +F + Q E +L P Sbjct: 82 QPKVYGGLEMSLPDFANCIVTLAGACAGTAWAFSLLCTH-SHQIAMFSKQLQDEIWLKDP 140 Query: 204 KLASGETVAAFC-LTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVF 262 + ++A F + E G LNG W S A+ V Sbjct: 141 DATASSSIAPFGKVEEVEGG------------------IILNGDYGWSSGCDHAEYAIVG 182 Query: 263 AKTPVTDPATGAVKEKITAF-VVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVP--- 318 D KI +F V+ R IK+S + + V +P Sbjct: 183 FNRFDADGN------KIYSFGVIPRSD--YEIVDNWYAQAIKSSGSKMLKLVNVFIPEYR 234 Query: 319 ---SENVLGEVGSGF------KVAMHILN-NGRFGMAAALAGTMRGIIAKAVDHATNRTQ 368 +++++ +GF K+ G +A G +I + NR + Sbjct: 235 ISKAKDMMEGKSAGFGLYPDSKIFYTPYRPYFASGFSAVSLGIAERMIEAFKEKQRNRVR 294 Query: 369 F--GEKIHNFGLIQEKLARMVMLQYVTESM---AYMVSANMDQGATDFQIEAAI----SK 419 G + ++A ++ + E ++ Sbjct: 295 AYTGANVGLATPALMRIAESTHQVAAARALLEKTWEDHRIHGLNHQYPNKETLAFWRTNQ 354 Query: 420 IFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTN-DILRLFVALQGC 477 + + + D + G FM ++R+ RD + T+ D+ + + Sbjct: 355 AYAVKMCIEAVDRLMAAAGATSFMDNSELQRLFRDAHMTGAHAYTDYDVCAQILGRELM 413 >2OR0-A nrPDB Length = 414 Score = 73.6 bits (179), Expect = 3e-13, Method: Composition-based stats. Identities = 70/381 (18%), Positives = 121/381 (31%), Gaps = 48/381 (12%) Query: 100 QFLKELVEPVSRFFEEVNDPA-KNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNT 158 Q + +++ + EE+ A +++A + + L++ GA L P GG + Sbjct: 20 QGMGRVLDRIEVVAEEIRGQAVQSEADCRLTDAAAGLLRDSGAIRLLQPRLYGGYEVHPR 79 Query: 159 QYARLVEIVGMHDLGVGITLGAHQSIGFKGI-LLFGTKA-QKEKYLPKLASGETVAAFCL 216 ++A V V D G G +G L F Q+E + GE + Sbjct: 80 EFAETVMGVAALDGASGWVTGI---VGVHPWELAFADPQVQEEIW------GEDNDTWMA 130 Query: 217 TEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVK 276 + + A P G Y L G + S + A V D G Sbjct: 131 S-------PYAPMGVATPVDGG--YVLKGRWSFSSGTDHCQWAFLGA--MVGDGEGGIAT 179 Query: 277 EKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVL------------- 323 ++ R I +G++ + + ++ DG VP L Sbjct: 180 PSSLHVILPRTDYQI-VEDTWDVIGLRGTGSKDLIVDGAFVPGYRTLNAAKVMDGRAQKE 238 Query: 324 -GEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQF-GEKIHNFGLIQE 381 G F + + G+ AA+ G G +A + +R G+KI + Sbjct: 239 AGRPEPLFNMPYSCMFP--LGITAAVIGITEGALACHIAVQKDRVAITGQKIKEDPYVLS 296 Query: 382 KLARMVMLQYVTESMAYMVSANM----DQGATDFQIEAAISKIFGSEAAWKVTDECIQIM 437 + + + D G E AI + AAW+ +I Sbjct: 297 AIGESAAEINASRVSLIETADRFYDKVDAGKEITFEERAIGRRTQIAAAWRAVRAADEIF 356 Query: 438 ---GGMGFMKEPGVERVLRDL 455 GG + ++R RD Sbjct: 357 ARAGGGALHYKTPMQRFWRDA 377 >3HWC-A nrPDB Length = 515 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 43/308 (13%), Positives = 86/308 (27%), Gaps = 46/308 (14%) Query: 80 GQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKEL 139 G D V +P ++ E V++F++ + P D L V+ + ++ Sbjct: 20 GNEKIDNVATHP---------LTRDYAERVAQFYDLHHRPDLQDVLTFVDADGVRRSRQ- 69 Query: 140 GAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVG------ITLGAHQSIGFKGILLFG 193 Q P + G+ + + ++ + G G Sbjct: 70 ----WQDPKDAAGLRVKRKYHETILREIAAGSYGRLPDAHNYTFTTYADDPEVWEKQSIG 125 Query: 194 TK-----AQKEKYLPKLASGETVAAFCLTEPSS--GSDAASIRTSAVP--SPCGKYYTLN 244 + +L L + +P + SDAA R+ + +N Sbjct: 126 AEGRNLTQNIHNFLKLLREKDLNCPLNFVDPQTDRSSDAAQARSPNLRIVEKTDDGIIVN 185 Query: 245 GSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKA 304 G K + D + G E++ + G+T E + Sbjct: 186 GVKAVGTGIAFGDYMHIGCL-----YRPGIPGEQVIFAAIPTNTPGVTVFCRESTVKNDP 240 Query: 305 SNT----------AEVFFDGVRVPSENV--LGEVGSGFKVAMHILNNGRFGMAAALAGTM 352 + + FD V +P E V +G I + + + Sbjct: 241 AEHPLASQGDELDSTTVFDNVFIPWEQVFHIGNPEHAKLYPQRIFDWVHYHILIRQVLRA 300 Query: 353 RGIIAKAV 360 I+ A+ Sbjct: 301 ELIVGLAI 308 >1U8V-A nrPDB Length = 490 Score = 38.2 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 44/284 (15%), Positives = 84/284 (29%), Gaps = 50/284 (17%) Query: 191 LFGT--KAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPC---------GK 239 +GT +YL + + + +T+P + SA P Sbjct: 122 KYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGD---RGLAPSAQKDPDLFLRIVEKRED 178 Query: 240 YYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGI-----THG 294 + G+K + + + +T+ +F G+ Sbjct: 179 GIVVRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAV----SFACPSDADGLFMIYGRQS 234 Query: 295 PPEKKM--------GIKASNTAE--VFFDGVRVPSENVLGEVGSGFKVAM--HILNNGRF 342 +KM G K E V FD V +P++ + F M R Sbjct: 235 CDTRKMEEGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHRQ 294 Query: 343 GMAAALAGTMR---GIIAKAVDHATNRTQFGEKIHNFGLIQEKLARM-VMLQYVTESMAY 398 G G A A D+ G + + +++KL M + + + Sbjct: 295 SYGGCKVGVGDVVIGAAALAADYN------GAQKASH--VKDKLIEMTHLNETLYCCGIA 346 Query: 399 MVSANMDQGATDFQIE---AAISKIFGSEAAWKVTDECIQIMGG 439 + A ++QI+ A + K + +++ I GG Sbjct: 347 CSAEGYPTAAGNYQIDLLLANVCKQNITRFPYEIVRLAEDIAGG 390 >2YYI-A nrPDB Length = 481 Score = 35.9 bits (81), Expect = 0.062, Method: Composition-based stats. Identities = 34/170 (20%), Positives = 55/170 (32%), Gaps = 24/170 (14%) Query: 254 GLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGI-----KASNT- 307 LAD +F T + + AF + G+ E +G ++ Sbjct: 187 PLADEVLIFPSTLLQAGSEKYAL----AFALPTSTPGLHFVCREALVGGDSPFDHPLSSR 242 Query: 308 -----AEVFFDGVRVPSENV--LG--EVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAK 358 V FD V VP E V LG E+ + A LN+ + A + Sbjct: 243 VEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAHQVVALKTAKTEAFLGV 302 Query: 359 AVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGA 408 A A G +G +QEK+A +++ + + A Sbjct: 303 AALMAE-----GIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKENA 347 >1AKL-A nrPDB Length = 470 Score = 33.9 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 37/123 (30%), Gaps = 18/123 (14%) Query: 143 GLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYL 202 GL GG G Y + E + + I G+ F +Y+ Sbjct: 361 GLGADQLWGGAGADTFVYGDIAESSAAAPDTLRDFVSGQDKIDLSGLDAFVNGGLVLQYV 420 Query: 203 PKLA--SGETVAAFCLTEPSSGSDAASIRTSAVPSPCGK---YYTLNGSKLWISNGGLAD 257 A +G+ + ++ + S A S+ G + +N I AD Sbjct: 421 DAFAGKAGQAILSY-----DAASKAGSLA----IDFSGDAHADFAIN----LIGQATQAD 467 Query: 258 IFT 260 I Sbjct: 468 IVV 470 >5LC3-A nrPDB Length = 205 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 37/85 (43%), Gaps = 6/85 (7%) Query: 400 VSANMDQGATDFQIEA--AISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRI 457 + A D GAT EA I+++ + + GG G + E+ +++ + Sbjct: 124 LMATYDDGATKLTDEARRLIAELGSTSITSLGFRDNWVFCGGKGIKTKSPFEQHIKNNKE 183 Query: 458 FRIFEGTNDILRLFVALQGCMDKGK 482 +EG ++ V ++GC+ + + Sbjct: 184 TNKYEGWPEV----VEMEGCIPQKQ 204 >4C9G-A nrPDB Length = 318 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 24/216 (11%), Positives = 59/216 (27%), Gaps = 10/216 (4%) Query: 360 VDHATNRTQFGEKIHNFGLIQEKLARMV-MLQYVTESMAYMVSANMDQGATDFQIEAAIS 418 +A F G+I +++Y + + F+ E + Sbjct: 65 RKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYA 124 Query: 419 KIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIF-----RIFEGTNDILRLFVA 473 K F A + ++ + + R+ D + R F G D+ + + Sbjct: 125 KWFAGNLASGGAAGALSLL--FVYSLDYARTRLAADSKSSKKGGARQFNGLIDVYKKTLK 182 Query: 474 LQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRA--GLGSGLSLSGLVHPELSR 531 G + + G + L + G L G V + Sbjct: 183 SDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLKPLLLTGSLEGSFLASFLLGWVVTTGAS 242 Query: 532 SGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQR 567 + + + + + + +K+ + ++ Sbjct: 243 TCSYPLDTVRRRMMMTSGQAVKYDGAFDCLRKIVAA 278 >6FPC-A nrPDB Length = 191 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 30/108 (27%), Gaps = 17/108 (15%) Query: 97 EQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGL-----------------KEL 139 ++ L +LV S + A LE + + L EL Sbjct: 2 QEQSILDKLVVLPSGEYNHSEAAAMKQRLEKIPTSILDALYSKGVKIKLTQGAITNEPEL 61 Query: 140 GAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFK 187 VP G GL + E V +G H S+ + Sbjct: 62 AYLKGVVPRGWEGTGLTWDDVPGVSERVVAVRIGYSEKGKGHNSLNLE 109 >4S1V-D nrPDB Length = 332 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 28/53 (52%), Gaps = 2/53 (3%) Query: 151 GGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLP 203 GG+GL T R + I G+ +G I H + IL++G++A ++K L Sbjct: 137 GGLGLGRTLSGRTLGIWGLGKIGQRIAQFGH--VFGMPILVWGSEASRQKALE 187 >5Y9S-A nrPDB Length = 304 Score = 30.1 bits (66), Expect = 3.6, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 35/95 (36%), Gaps = 19/95 (20%) Query: 82 LTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGA 141 L DQ PY L+ + FL ++VEPV + P + E T + L ++ Sbjct: 194 LKADQTIPY---LSYSEHTFLSKVVEPVLKTLPLTLKP-------VFETTLSESLVKMAI 243 Query: 142 FGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGI 176 GG G+ + E + H L + Sbjct: 244 ---------GGAGVAWVPMHVIEEELAQHRLVIAF 269 >1V9S-A nrPDB Length = 208 Score = 28.5 bits (62), Expect = 9.0, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 24/60 (40%), Gaps = 11/60 (18%) Query: 372 KIHNFGLIQEKLARM-----------VMLQYVTESMAYMVSANMDQGATDFQIEAAISKI 420 + + L+Q KLA + + + V MAY +++ T + A +++ Sbjct: 4 TLVDHPLVQHKLAHLRDKRTGPKDFRELAEEVAMLMAYEAMRDLELEETTVETPIAPARV 63 >2DUB-A nrPDB Length = 261 Score = 28.5 bits (62), Expect = 9.2, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 35/87 (40%), Gaps = 1/87 (1%) Query: 350 GTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQ-GA 408 G + + +A + QFG+ G I + + V +S+A + D+ A Sbjct: 112 GGCELAMMCDIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISA 171 Query: 409 TDFQIEAAISKIFGSEAAWKVTDECIQ 435 D + +SKIF E + +C + Sbjct: 172 QDAKQAGLVSKIFPVETLVEEAIQCAE 198 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.130 0.337 Lambda K H 0.267 0.0402 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,727,983 Number of Sequences: 36641 Number of extensions: 905159 Number of successful extensions: 3409 Number of sequences better than 10.0: 99 Number of HSP's better than 10.0 without gapping: 136 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 2765 Number of HSP's gapped (non-prelim): 188 length of query: 655 length of database: 10,336,785 effective HSP length: 103 effective length of query: 552 effective length of database: 6,562,762 effective search space: 3622644624 effective search space used: 3622644624 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.5 bits)