BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P48735 (452 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5I96-A nrPDB 946 0.0 6BL1-B nrPDB 600 e-172 3US8-A nrPDB 592 e-169 4HCX-A nrPDB 560 e-160 2QFY-A nrPDB 530 e-151 4AOY-A nrPDB 468 e-132 1ZOR-A nrPDB 432 e-121 2UXQ-A nrPDB 406 e-114 2IV0-A nrPDB 51 8e-07 1AI3-A nrPDB 49 6e-06 3U1H-A nrPDB 48 1e-05 1HQS-A nrPDB 46 3e-05 2D1C-A nrPDB 46 3e-05 3TY3-A nrPDB 46 4e-05 5YVT-A nrPDB 43 2e-04 3VMJ-A nrPDB 43 3e-04 3VML-A nrPDB 42 4e-04 1CNZ-A nrPDB 42 5e-04 1XGV-A nrPDB 42 5e-04 1A05-A nrPDB 42 7e-04 3BLX-A nrPDB 41 0.001 3VMK-A nrPDB 40 0.001 1V5B-A nrPDB 40 0.002 4IWH-A nrPDB 39 0.004 1CM7-A nrPDB 38 0.009 1WPW-A nrPDB 38 0.009 4Y1P-A nrPDB 37 0.023 3ASJ-A nrPDB 36 0.027 1VLC-A nrPDB 35 0.061 1XAD-A nrPDB 35 0.083 1IDM-A nrPDB 34 0.11 3UDO-A nrPDB 32 0.55 4ZDA-A nrPDB 29 3.2 1J10-A nrPDB 28 7.7 >5I96-A nrPDB Length = 458 Score = 946 bits (2445), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/452 (99%), Positives = 452/452 (100%) Query: 1 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR 60 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR Sbjct: 1 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR 60 Query: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE Sbjct: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120 Query: 121 ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180 ARVEEFKLKKMWKSPNGTI+NILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK Sbjct: 121 ARVEEFKLKKMWKSPNGTIQNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180 Query: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI Sbjct: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240 Query: 241 QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS 300 QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS Sbjct: 241 QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS 300 Query: 301 SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK 360 SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK Sbjct: 301 SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK 360 Query: 361 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH 420 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH Sbjct: 361 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH 420 Query: 421 GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452 GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ Sbjct: 421 GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452 >6BL1-B nrPDB Length = 425 Score = 600 bits (1547), Expect = e-172, Method: Compositional matrix adjust. Identities = 282/403 (69%), Positives = 330/403 (81%), Gaps = 2/403 (0%) Query: 50 VVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSV 109 VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD T+DQVT D+A A +K++V Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNV 69 Query: 110 AVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPIT 169 VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPII 129 Query: 170 IGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGMYNTDESI 228 IGRHA+GDQY+ATDFV G ++ +TP DG+ + V+NF GGV MGMYN D+SI Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSI 189 Query: 229 SGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHR 288 FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+ KIWYEHR Sbjct: 190 EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR 249 Query: 289 LIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAH 348 LIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT+EAEAAH Sbjct: 250 LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAH 309 Query: 349 GTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVES 408 GTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V +ET+E+ Sbjct: 310 GTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEA 369 Query: 409 GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451 G MTKDLA CI GL NV+ ++ +LNT +F+D + NL L + Sbjct: 370 GFMTKDLAACIKGLPNVQRSD-YLNTFEFMDKLGENLKIKLAQ 411 >3US8-A nrPDB Length = 427 Score = 592 bits (1525), Expect = e-169, Method: Compositional matrix adjust. Identities = 281/408 (68%), Positives = 331/408 (81%), Gaps = 7/408 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +IKVA PVVE+DGDEMTRIIWQFIK+KLI P++D+ L+Y+DLG+ NRD TDDQVTID+A Sbjct: 26 KIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTIDAAN 85 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A +K+ V VKCATITPDE RVEEFKLKKMWKSPNGTIRNILGG +FREPIICKN+PRLVP Sbjct: 86 AIKKHGVGVKCATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRLVP 145 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMY 222 GWTKPI +GRHA GDQY+ATDF G + F +DG + E +VY+ P GV + MY Sbjct: 146 GWTKPIIVGRHAFGDQYRATDFKFPGKGKLSIKFVGEDGQTI-EHDVYDAPGAGVALAMY 204 Query: 223 NTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNK 282 N DESI+ FA + F Y +Q+K P+Y+STKNTILKAYDGRFKDIFQ++FD+ + F K Sbjct: 205 NLDESITEFARASFNYGLQRKVPVYLSTKNTILKAYDGRFKDIFQKVFDEEFAAQFKAEK 264 Query: 283 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 +WYEHRLIDDMVA LK SGG+VWACKNYDGDVQSDI+AQGFGSLGLMTSVL+ PDGKT+ Sbjct: 265 LWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDGKTV 324 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 EAEAAHGTVTRHYR+HQKG TSTN IASIFAWTRGL HR KLDGN +L +F++ LE+VC Sbjct: 325 EAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDGNAELAKFSETLERVC 384 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450 V+TVESG MTKDLA I ++ +L+TT FLD I NL +A+ Sbjct: 385 VDTVESGFMTKDLALLIGP------DQPWLSTTGFLDKIDENLRKAMA 426 >4HCX-A nrPDB Length = 409 Score = 560 bits (1443), Expect = e-160, Method: Compositional matrix adjust. Identities = 266/409 (65%), Positives = 321/409 (78%), Gaps = 7/409 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +IKV+ PVVE+DGDEMTR+IW+ IK+ LILP++DI+L Y+DLG+ +RD TDDQVTID+A Sbjct: 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A +K+ V VKCATITPDEARVEEF LKKMW SPNGTIRNILGGT+FREPI+ N+PRLVP Sbjct: 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA-GGVGMGM 221 GWTKPI IGRHA GDQY+AT+F D+ GT + FTP DGS E+ + P GGV +GM Sbjct: 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 Query: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281 YN ESI FA + F Y + KWP+Y+STKNTILKAYDG FKD F+ ++++ +K F+ Sbjct: 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 Query: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + YEHRLIDDMVA LK GG+VWACKNYDGDVQSD +AQG+GSLGLMTSVL+ DGKT Sbjct: 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401 +EAEAAHGTVTRHYR++Q G+PTSTNPIASIFAWTRGL+HRGKLDG ++I FA LE V Sbjct: 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 Query: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450 + TVESG MTKDLA I + +LN+ +FLD I NL++ L Sbjct: 366 VIATVESGKMTKDLAILIGP------EQDWLNSEEFLDAIADNLEKELA 408 >2QFY-A nrPDB Length = 427 Score = 530 bits (1364), Expect = e-151, Method: Compositional matrix adjust. Identities = 257/415 (61%), Positives = 317/415 (76%), Gaps = 9/415 (2%) Query: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98 +A +IKV +PVVE+DGDEMTRIIW IK+KLILP++D+ LKY+DL + +RD T D++T Sbjct: 14 HAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQ 73 Query: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158 D+A A +KY V +KCATITPDEARV+EF L KMWKSPNGTIRNILGGTVFREPI+ IP Sbjct: 74 DAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIP 133 Query: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVK--EWEVYNFPAGG 216 RLVP W KPI IGRHAHGDQYKATD + G+ ++V+ P D + + +VY++ G Sbjct: 134 RLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSG 193 Query: 217 VGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKT 276 V M MYNTDESI GFAHS F+ AI KK L++STKNTILK YDGRFKDIFQE+++ YK+ Sbjct: 194 VAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKS 253 Query: 277 DFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVC 336 F++ I YEHRLIDDMVAQ++KS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+LV Sbjct: 254 KFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVT 313 Query: 337 PDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQ 396 PDGKT E+EAAHGTVTRHYR++QKG TSTN IASIFAW+RGL RG+LD L +FA Sbjct: 314 PDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFAN 373 Query: 397 MLEKVCVETVES-GAMTKDLA-GCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449 +LE + TV+ G MTKDLA C + + ++ T +FLD ++ L + + Sbjct: 374 ILESATLNTVQQDGIMTKDLALACGNNERSA-----YVTTEEFLDAVEKRLQKEI 423 >4AOY-A nrPDB Length = 402 Score = 468 bits (1205), Expect = e-132, Method: Compositional matrix adjust. Identities = 229/404 (56%), Positives = 291/404 (72%), Gaps = 7/404 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +IK+ P+VEMDGDEMTRIIW+ IKE L+ P++++ +Y+DLGL NRD+T+DQVTID+A Sbjct: 3 KIKMKVPLVEMDGDEMTRIIWRLIKENLLEPYIELNTEYYDLGLENRDKTEDQVTIDAAR 62 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A QKY V VKCATITP+ RVEE+ LKKMWKSPNGTIR IL GTVFR PI+ +I V Sbjct: 63 AIQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPIVVNSIKPFVK 122 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMY 222 GW KPI+I RHA+GD YK ++ AG ++VFT ++G V ++ F GV MGM+ Sbjct: 123 GWKKPISIARHAYGDVYKNVEYYVPSAGKAELVFTSENGE-VSRQTIHEFDGPGVIMGMH 181 Query: 223 NTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNK 282 NTD+SI FA +CF YA+ L+ STK+TI K YD RFKDIFQEI++ YK F+ Sbjct: 182 NTDKSIRSFARACFNYALDMNQDLWFSTKDTISKTYDHRFKDIFQEIYENEYKEKFEAKN 241 Query: 283 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 + Y + LIDD VA++++S GG VWACKNYDGDV SD++A FGSL +MTSVLV PDGK Sbjct: 242 LQYFYTLIDDAVARIIRSEGGMVWACKNYDGDVMSDMVASAFGSLAMMTSVLVSPDGK-Y 300 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 E EAAHGTVTRHY +H KG TSTN +A+IFAWT L+ RG+LDG ++L+ FA LE+ Sbjct: 301 EFEAAHGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRGELDGIKELVDFATKLEQAS 360 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLD 446 V+T+E+G MTKDLA LS V + +NT DFL I+ + Sbjct: 361 VQTIENGVMTKDLA----SLSEVP-EKKIVNTEDFLKEIRKTFE 399 >1ZOR-A nrPDB Length = 399 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 214/408 (52%), Positives = 280/408 (68%), Gaps = 10/408 (2%) Query: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101 +++KV P+VE+DGDEM R++W+ IKEKLILP++DIQL YFDLG+ RD+TDDQ+TI++A Sbjct: 2 EKVKVKNPIVELDGDEMARVMWKMIKEKLILPYLDIQLVYFDLGIKKRDETDDQITIEAA 61 Query: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161 A +KY V VKCATITPD RV+E+ LKK WKSPN TIR L GTVFR+PI+ KN+P LV Sbjct: 62 KAIKKYGVGVKCATITPDAERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLV 121 Query: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGM 221 W KPI IGRHA+GD Y A + + ++V K+ K V+ F GV M M Sbjct: 122 KRWKKPIIIGRHAYGDIYNAVEAKVEGPAEVELVVRNKEN---KTLLVHKFEGNGVVMAM 178 Query: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281 +N ++SI FA SC YAI +K ++ +TK+TI K Y FKDIFQE DK K + +K Sbjct: 179 HNLEKSIRSFAQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKR-KEELEKA 237 Query: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + Y + LIDD AQ+L+S GG +WAC NY+GD+ SD++A GFGSLGLMTSVLV PDG Sbjct: 238 GVNYRYMLIDDAAAQILRSEGGMLWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDG-V 296 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401 E EAAHGTV RHY + KG TSTNP ASIFAWT + RG+LDG ++ FA LEK Sbjct: 297 YEFEAAHGTVRRHYYRYLKGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKA 356 Query: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449 + T+ESG +TKDL + +++ ++ +F+D +K NL++ L Sbjct: 357 VINTIESGVITKDL----QPFTEPPIDK-YVTLEEFIDEVKKNLEKLL 399 >2UXQ-A nrPDB Length = 402 Score = 406 bits (1044), Expect = e-114, Method: Compositional matrix adjust. Identities = 201/405 (49%), Positives = 278/405 (68%), Gaps = 7/405 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +I++ P+VE+DGDEMTR++W IK+KL+LP +D+Q +Y+DLG+ RD+T+DQ+TID+A Sbjct: 2 KIQMKTPLVELDGDEMTRVLWPLIKDKLLLPFIDLQTEYYDLGIEERDRTNDQITIDAAE 61 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A +KY V VK ATITP++ RVEE+ LK+ WKSPN T+R +L GTVFR+PI+ KNI V Sbjct: 62 AIKKYGVGVKNATITPNQDRVEEYGLKEQWKSPNATVRAMLDGTVFRKPIMVKNIKPSVR 121 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMY 222 W KPI +GRHA+GD YK + A+ G ++V T K+G ++ + + G++ Sbjct: 122 SWQKPIVVGRHAYGDFYKNAEIFAEAGGKLEIVVTDKNGKETRQ-TIMEVDEPAIVQGIH 180 Query: 223 NTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNK 282 NT SI FA +CF+Y++ +K + +TK+TI K YD RFK IF+EIF + YK F Sbjct: 181 NTVASIGHFARACFEYSLDQKIDCWFATKDTISKQYDQRFKIIFEEIFAQEYKEKFAAAG 240 Query: 283 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 I Y + LIDD+VA+++K+ GG +WACKNYDGDV SD++A FGSL +M+SVLV P G Sbjct: 241 IEYFYTLIDDVVARMMKTEGGMLWACKNYDGDVMSDMVASAFGSLAMMSSVLVSPYG-YF 299 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 E EAAHGTV RHY +H KG TSTNP+A I+AWT L RG+LDG DL F LE + Sbjct: 300 EYEAAHGTVQRHYYQHLKGERTSTNPVALIYAWTGALRKRGELDGTPDLCAFCDSLEAIT 359 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR 447 +E +ESG MT DLA I + +K+ L++ +F+D + L + Sbjct: 360 IECIESGYMTGDLAR-ICEPAAIKV----LDSIEFIDELGKRLQQ 399 >2IV0-A nrPDB Length = 412 Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 87/371 (23%), Positives = 147/371 (39%), Gaps = 68/371 (18%) Query: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII-CKNI 157 D+ A +++ VA+K TP + ++S N TIR +L P+ K + Sbjct: 83 DTLNAIKEFRVALKGPLTTP---------VGGGYRSLNVTIRQVLDLYANVRPVYYLKGV 133 Query: 158 PRLVPGWTK-PITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGG 216 P + K I R D Y ++ K++ K+ GV E G Sbjct: 134 PSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEFGVTIRE-----DSG 188 Query: 217 VGMGMYNTDESISGFA-----HSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKD------ 264 +G+ + IS FA +YAI+ + + + K I+K +G F+D Sbjct: 189 IGI------KPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVA 242 Query: 265 ---------IFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGD 314 E++DK Y + KI + R+ D+M Q+L + + V A N +GD Sbjct: 243 KQEFGEYCITEDELWDK-YGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGD 301 Query: 315 VQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFA 374 SD A G LG+ + DG + E HG+ ++ +++ NP A I Sbjct: 302 YLSDAAAALIGGLGIAPGSNIG-DGIGV-FEPVHGSAPKYAGQNK------VNPTAEILT 353 Query: 375 WTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNT 434 E+ G D ++M++K T+ SG +T D+ + G + T Sbjct: 354 GALMFEYIGWKDA-------SEMIKKAVEMTISSGIVTYDIHRHMGGTK--------VGT 398 Query: 435 TDFLDTIKSNL 445 +F + + NL Sbjct: 399 REFAEAVVENL 409 >1AI3-A nrPDB Length = 416 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 73/309 (23%), Positives = 122/309 (39%), Gaps = 42/309 (13%) Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSP-NGTIRNILGGTVFREPI---ICKNIP 158 +TQ Y V T D R +K +P G IR++ R+ + IC Sbjct: 74 STQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSL--NVALRQELDLYICLRPV 131 Query: 159 RLVPGWTKPI--------TIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVY 210 R G P+ I R D Y ++ AD A K++ ++ GVK+ Sbjct: 132 RYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKK---I 188 Query: 211 NFPAGGVGMGMYN-TDESISGFAHSCFQYAI-QKKWPLYMSTKNTILKAYDGRFKDIFQE 268 FP G+G+ ++E + +YAI + + + K I+K +G FKD + Sbjct: 189 RFPEH-CGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQ 247 Query: 269 IFDKHYKTDFDKNKIWYEHR--------LIDDMVA-----QVLKSSGGF-VWACKNYDGD 314 + + + + W + + +I D++A Q+L + V AC N +GD Sbjct: 248 LAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGD 307 Query: 315 VQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFA 374 SD LA G +G+ + + EA HGT ++ + + NP + I + Sbjct: 308 YISDALAAQVGGIGIAPGANIGDECALF--EATHGTAPKYAGQDK------VNPGSIILS 359 Query: 375 WTRGLEHRG 383 L H G Sbjct: 360 AEMMLRHMG 368 >3U1H-A nrPDB Length = 390 Score = 47.8 bits (112), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 50/221 (22%), Positives = 98/221 (44%), Gaps = 31/221 (14%) Query: 224 TDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKI 283 T E I F+ A+ +K + K +L++ ++++ +E+ ++ + Sbjct: 184 TREEIERIIRKAFELALTRKKKVTSVDKANVLES-SRLWREVAEEVAKEYPDVEL----- 237 Query: 284 WYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 EH L+D+ Q++++ F V +N GD+ SD + GSLG++ S + DG + Sbjct: 238 --EHMLVDNAAMQLIRNPRQFDVIVTENMFGDILSDEASMITGSLGMLPSASLSTDGLGL 295 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 E HG+ G+ + NP+A+I + L + L+ A+ +EK Sbjct: 296 -YEPVHGSAP-----DIAGKGIA-NPLATILSAAMMLRYSFGLEEE------AKAIEKAV 342 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKS 443 + + G T D+A K +++TT+ D +K+ Sbjct: 343 EKVLAEGYRTADIA---------KPGGKYVSTTEMTDEVKA 374 >1HQS-A nrPDB Length = 423 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 55/234 (23%), Positives = 92/234 (39%), Gaps = 41/234 (17%) Query: 224 TDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYK------T 276 ++E S + YAI+ + + + K I+K +G FK+ E+ +K Y Sbjct: 193 SEEGTSRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAEKEYGDKVFTWA 252 Query: 277 DFDK--------------------NKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDV 315 +D+ KI + + D + Q+L F V A N +GD Sbjct: 253 QYDRIAEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEFDVVATMNLNGDY 312 Query: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375 SD LA G +G+ + + EA HGT ++ + NP + I + Sbjct: 313 ISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDK------VNPSSVILSG 366 Query: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNE 429 LEH G + A ++ K +T+ S +T D A + G + VK +E Sbjct: 367 VLLLEHLGWNEA-------ADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSE 413 >2D1C-A nrPDB Length = 496 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 51/225 (22%), Positives = 94/225 (41%), Gaps = 36/225 (16%) Query: 225 DESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIW 284 E I FA + +KK ++ +TK+ I+K +G K F+++ ++ I Sbjct: 167 SEKIVRFAFELARAEGRKK--VHCATKSNIMKLAEGTLKRAFEQVAQEY-------PDIE 217 Query: 285 YEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIE 343 H ++D+ Q++K F V N +GD+ SD+ + G LG S + + Sbjct: 218 AVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTSGLIGGLGFAPSANIGNEVAIF- 276 Query: 344 AEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCV 403 EA HG+ ++ ++ NP A + + L + + A ++E + Sbjct: 277 -EAVHGSAPKYAGKN------VINPTAVLLSAVMMLRYLEEFA-------TADLIENALL 322 Query: 404 ETVESG-AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR 447 T+E G +T D+ G G TT++ + I NL + Sbjct: 323 YTLEEGRVLTGDVVGYDRG----------AKTTEYTEAIIQNLGK 357 >3TY3-A nrPDB Length = 366 Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 49/183 (26%), Positives = 81/183 (44%), Gaps = 23/183 (12%) Query: 238 YAIQKKWPLYMSTKNTILKAYDGRFKDIFQ--EIFDKHYKTDFDKNKIWYEHRLIDDMVA 295 Y+I KK + + K+ ++ DG F++ + + D Y + I + +++D MV Sbjct: 187 YSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYAS------INVDEQIVDSMVY 240 Query: 296 QVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354 ++ + F V N GD+ SD A GSLGL+ S V + + +E HG+ Sbjct: 241 RLFREPECFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDN--FVMSEPVHGSAP-- 296 Query: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414 GR + NP+A+ + LE G D D+ ++KV E +T D Sbjct: 297 ---DIAGRGIA-NPVATFRSVALMLEFMGHQDAAADIY---TAVDKVL---TEGKVLTPD 346 Query: 415 LAG 417 L G Sbjct: 347 LGG 349 >5YVT-A nrPDB Length = 339 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 24/190 (12%) Query: 231 FAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRL 289 A F+YA + + K I++ DG F +E+ + F N+++ Sbjct: 152 IAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKF--NEMY----- 204 Query: 290 IDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAH 348 +D + +++ F V N GD+ SD+ A G LG+ S + +G I E+ H Sbjct: 205 LDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVH 263 Query: 349 GTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVES 408 GT + NP A + + L H G D A +E C T++ Sbjct: 264 GTAPDIAGKDM------ANPTALLLSAVMMLRHMGLFD-------HAARIEAACFATIKD 310 Query: 409 G-AMTKDLAG 417 G ++TKDL G Sbjct: 311 GKSLTKDLGG 320 >3VMJ-A nrPDB Length = 375 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 22/196 (11%) Query: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280 M + IS A F+ A ++ + K +L A ++ + +E+ DF Sbjct: 174 MRYSRREISRIARIAFEAARGRRKKVTSVDKANVL-ACSVLWRQVVEEV-----AVDFPD 227 Query: 281 NKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDG 339 + EH ID+ Q+L+ F V C N GD+ SD +A GS+GL++S + G Sbjct: 228 --VELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTG 285 Query: 340 KTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLE 399 + E A G+ G+ + NPIA I + L H K + A +E Sbjct: 286 FGL-FEPAGGSAP-----DIAGKGIA-NPIAQILSAALMLRHSLKQE------EAASAIE 332 Query: 400 KVCVETVESGAMTKDL 415 + + + SG +T +L Sbjct: 333 RAVTKALNSGYLTGEL 348 >3VML-A nrPDB Length = 375 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/138 (28%), Positives = 60/138 (43%), Gaps = 14/138 (10%) Query: 279 DKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337 D + EH ID+ Q+L+ F V C N GD+ SD +A GS+GL+ S+ + Sbjct: 224 DYPDVELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNS 283 Query: 338 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQM 397 G + E A G+ + NP+A I + L H KL+ A Sbjct: 284 QGFGM-YEPAGGSAPDIAGQ------GIANPVAQILSAALLLRHSLKLEDA------ALA 330 Query: 398 LEKVCVETVESGAMTKDL 415 +E + + SG +T +L Sbjct: 331 IEAAVSKALNSGYLTGEL 348 >1CNZ-A nrPDB Length = 363 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 51/190 (26%), Positives = 78/190 (41%), Gaps = 22/190 (11%) Query: 228 ISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEH 287 I A F+ A +++ + K +L++ +++EI + KT D + H Sbjct: 172 IERIARIAFESARKRRRKVTSIDKANVLQS-----SILWREIVNDVAKTYPD---VELAH 223 Query: 288 RLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346 ID+ Q++K F V C N GD+ SD A GS+G++ S + G + E Sbjct: 224 MYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEP 282 Query: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETV 406 A G+ NPIA I + L R LD N A +E+ + Sbjct: 283 AGGSAP------DIAGKNIANPIAQILSLA--LLLRYSLDANDA----ATAIEQAINRAL 330 Query: 407 ESGAMTKDLA 416 E G T DLA Sbjct: 331 EEGVRTGDLA 340 >1XGV-A nrPDB Length = 435 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 48/209 (22%), Positives = 92/209 (44%), Gaps = 29/209 (13%) Query: 251 KNTILKAYDGRFK----DIFQEIFDKHYKTDFD----------KNKIWYEHRLIDDMVAQ 296 K I+K +G F ++ E F +H T+ + + KI R+ D+M+ Q Sbjct: 233 KGNIMKYTEGAFMRWAYEVALEKFREHVVTEQEVQEKYGGVRPEGKILVNDRIADNMLQQ 292 Query: 297 VLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355 ++ + V N +GD SD + G +G M + + DG + AE HGT ++ Sbjct: 293 IITRPWDYQVIVAPNLNGDYISDAASALVGGIG-MAAGMNMGDGIAV-AEPVHGTAPKYA 350 Query: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415 + NP A I + + + G+ G +++ ++E + V+S +T+DL Sbjct: 351 GKDL------INPSAEILSASLLI---GEFMGWREV---KSIVEYAIRKAVQSKKVTQDL 398 Query: 416 AGCIHGLSNVKLNEHFLNTTDFLDTIKSN 444 A + G+ ++ +E+ ++D N Sbjct: 399 ARHMPGVQPLRTSEYTETLIAYIDEADLN 427 >1A05-A nrPDB Length = 358 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 49/214 (22%), Positives = 92/214 (42%), Gaps = 24/214 (11%) Query: 205 KEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKD 264 + EV + G +Y+ DE I AH F+ A ++ L K +L+ Sbjct: 145 RGLEVIDGKRRGFNTMVYDEDE-IRRIAHVAFRAAQGRRKQLCSVDKANVLET-----TR 198 Query: 265 IFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQG 323 +++E+ + + D + H +D+ Q++++ F V N GD+ SD +Q Sbjct: 199 LWREVVTEVAR---DYPDVRLSHMYVDNAAMQLIRAPAQFDVLLTGNMFGDILSDEASQL 255 Query: 324 FGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRG 383 GS+G++ S + +G+ + E HG+ + + NP+A+I + L H Sbjct: 256 TGSIGMLPSASLG-EGRAMY-EPIHGSAPDIAGQDK------ANPLATILSVAMMLRH-- 305 Query: 384 KLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAG 417 L+ +AQ +E ++ G T D+A Sbjct: 306 SLNAEP----WAQRVEAAVQRVLDQGLRTADIAA 335 >3BLX-A nrPDB Length = 349 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 83/215 (38%), Gaps = 38/215 (17%) Query: 236 FQYAIQKKWPLYMST---KNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDD 292 F + KK+ T K I+K DG F++I EI K Y D D + I ++D+ Sbjct: 165 FAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEYP-DIDVSSI-----IVDN 218 Query: 293 MVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTV 351 Q + F V + G + +I A G GL+ D E Sbjct: 219 ASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANFGRDYAVFEPG------ 272 Query: 352 TRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGA- 410 +RH KG+ + NP A I + T L H G L +A + K ET+ G Sbjct: 273 SRHVGLDIKGQNVA-NPTAMILSSTLMLNHLG-------LNEYATRISKAVHETIAEGKH 324 Query: 411 MTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445 T+D+ G +TTDF + I + L Sbjct: 325 TTRDIGGS-------------SSTTDFTNEIINKL 346 >3VMK-A nrPDB Length = 375 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 49/109 (44%), Gaps = 8/109 (7%) Query: 279 DKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCP 337 D + EH ID+ Q+L+ F V C N GD+ SD +A GS+GL+ S+ + Sbjct: 224 DYPDVELEHIYIDNATMQLLRRPNEFDVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNS 283 Query: 338 DGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLD 386 G + E A G+ + NP+A I + L H KL+ Sbjct: 284 QGFGM-YEPAGGSAPDIAGQ------GIANPVAQILSAALLLRHSLKLE 325 >1V5B-A nrPDB Length = 366 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 54/241 (22%), Positives = 98/241 (40%), Gaps = 31/241 (12%) Query: 177 DQYKATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235 ++ + D V R T + F P + G E EV + + T E I Sbjct: 123 ERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDT--------LAYTREEIERIIEKA 174 Query: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 295 FQ A ++ L K +L++ +++I +E K+ + H L+D Sbjct: 175 FQLAQIRRKKLASVDKANVLESSR-MWREIAEETAKKYPDVELS-------HMLVDSTAM 226 Query: 296 QVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354 Q++ + G F V +N GD+ SD+ + GSLG++ S + D + E HG+ Sbjct: 227 QLIANPGQFDVIVTENMFGDILSDLASVITGSLGMLPSASLRSD-RFGMYEPVHGSAPDI 285 Query: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414 + + NP+ ++ + L + L+ + A +EK + ++ G T D Sbjct: 286 AGQGK------ANPLGTVLSAALMLRYSFGLE------KEAAAIEKAVDDVLQDGYCTGD 333 Query: 415 L 415 L Sbjct: 334 L 334 >4IWH-A nrPDB Length = 363 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 60/264 (22%), Positives = 106/264 (40%), Gaps = 43/264 (16%) Query: 158 PRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGV 217 P LV G I I R +GD Y G + V DG E E ++ Sbjct: 124 PELVAGLD--ILIVRELNGDIY---------FGQPRGVRAAPDGPFAGEREGFDT----- 167 Query: 218 GMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTD 277 M ++ + AH FQ A ++ L K+ +L+ ++D+ ++ ++ + Sbjct: 168 ---MRYSEPEVRRIAHVAFQAAQKRAKKLLSVDKSNVLETSQ-FWRDVMIDVSKEYADVE 223 Query: 278 FDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVC 336 H +D+ Q+ K+ F V N GD+ SD + GS+G++ S + Sbjct: 224 L-------SHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLD 276 Query: 337 PDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQ 396 + K + E +HG+ G+ + NP+A+I + L + + + A Sbjct: 277 KNNKGLY-EPSHGSAP-----DIAGKGIA-NPLATILSAAMLLRY------SLNRAEQAD 323 Query: 397 MLEKVCVETVESGAMTKDLA--GC 418 +E+ +E G T D+A GC Sbjct: 324 RIERAVKTVLEQGYRTGDIATPGC 347 >1CM7-A nrPDB Length = 363 Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust. Identities = 48/190 (25%), Positives = 77/190 (40%), Gaps = 22/190 (11%) Query: 228 ISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEH 287 I A F+ A +++ + K +L++ +++I EI ++ + H Sbjct: 172 IERIARIAFESARKRRHKVTSIDKANVLQS-SILWREIVNEIATEYPDVEL-------AH 223 Query: 288 RLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEA 346 ID+ Q++K F V C N GD+ SD A GS+G++ S + G + E Sbjct: 224 MYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEP 282 Query: 347 AHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETV 406 A G+ NPIA I + L R LD + A +E+ + Sbjct: 283 AGGSAP------DIAGKNIANPIAQILSLA--LLLRYSLDADDA----ACAIERAINRAL 330 Query: 407 ESGAMTKDLA 416 E G T DLA Sbjct: 331 EEGIRTGDLA 340 >1WPW-A nrPDB Length = 336 Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust. Identities = 48/209 (22%), Positives = 87/209 (41%), Gaps = 28/209 (13%) Query: 216 GVGMGMYNTDESISGFAHS-----CFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIF 270 GV +GM + I+ FA +A++++ + K +++ DG F + + + Sbjct: 133 GVAVGM----KIITRFASERIAKVGLNFALRRRKKVTCVHKANVMRITDGLFAEACRSVL 188 Query: 271 DKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGL 329 K K+ Y +D A ++++ F V +N GD+ SD +Q GSLG+ Sbjct: 189 ---------KGKVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDILSDEASQIAGSLGI 239 Query: 330 MTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQ 389 S + D K + E HG NP A + + + E +L + Sbjct: 240 APSANIG-DKKAL-FEPVHGAA------FDIAGKNIGNPTAFLLSVSMMYERMYELSNDD 291 Query: 390 DLIRFAQMLEK-VCVETVESGAMTKDLAG 417 I+ ++ LE + + E A+T D+ G Sbjct: 292 RYIKASRALENAIYLVYKERKALTPDVGG 320 >4Y1P-A nrPDB Length = 337 Score = 36.6 bits (83), Expect = 0.023, Method: Compositional matrix adjust. Identities = 25/103 (24%), Positives = 45/103 (43%), Gaps = 10/103 (9%) Query: 231 FAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLI 290 A A+++K + K+ +++ DG F + + + K K+ Y + Sbjct: 150 IAQVALNQALRRKKKVVCVHKSNVMRITDGLFAESCRNVL---------KGKVEYSEMYV 200 Query: 291 DDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTS 332 D A ++++ F V +N GD+ SD Q GSLG+ S Sbjct: 201 DAAAANLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPS 243 >3ASJ-A nrPDB Length = 334 Score = 36.2 bits (82), Expect = 0.027, Method: Compositional matrix adjust. Identities = 43/173 (24%), Positives = 68/173 (39%), Gaps = 23/173 (13%) Query: 246 LYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF- 304 L+++ K +L G F D +E+ DF + + ++D+ Q++ F Sbjct: 166 LHIAHKANVLPLTQGLFLDTVKEV-----AKDFPL--VNVQDIIVDNCAMQLVMRPERFD 218 Query: 305 VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPT 364 V N GD+ SD+ A G LGL P G + A V H Sbjct: 219 VIVTTNLLGDILSDLAAGLVGGLGL------APSGNIGDTTAVFEPV--HGSAPDIAGKG 270 Query: 365 STNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAG 417 NP A+I + L++ G+ + A+ +EK +E G T DL G Sbjct: 271 IANPTAAILSAAMMLDYLGEKEA-------AKRVEKAVDLVLERGPRTPDLGG 316 >1VLC-A nrPDB Length = 366 Score = 35.0 bits (79), Expect = 0.061, Method: Compositional matrix adjust. Identities = 38/131 (29%), Positives = 56/131 (42%), Gaps = 16/131 (12%) Query: 287 HRLIDDMVAQ-VLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAE 345 H +D+ Q +LK S V N GD+ SD A GSLGL+ S G E Sbjct: 227 HIYVDNAAMQLILKPSQFDVILTTNMFGDILSDESAALPGSLGLLPS---ASFGDKNLYE 283 Query: 346 AAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVET 405 A G+ ++ NPIA I + LEH + ++ A+ +E+ Sbjct: 284 PAGGSAPDIAGKN------IANPIAQILSLAMMLEH------SFGMVEEARKIERAVELV 331 Query: 406 VESGAMTKDLA 416 +E G T+D+A Sbjct: 332 IEEGYRTRDIA 342 >1XAD-A nrPDB Length = 345 Score = 34.7 bits (78), Expect = 0.083, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 9/100 (9%) Query: 283 IWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + EH+ +D M +++S F V N GD+ SD+ + GSLGL+ S + Sbjct: 209 VALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASLGRGTPV 268 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEH 381 E HG+ G+ + NP A+I + LEH Sbjct: 269 F--EPVHGSAP-----DIAGKGIA-NPTAAILSAAMMLEH 300 >1IDM-A nrPDB Length = 343 Score = 34.3 bits (77), Expect = 0.11, Method: Compositional matrix adjust. Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 9/100 (9%) Query: 283 IWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + EH+ +D M +++S F V N GD+ SD+ + GSLGL+ S + Sbjct: 207 VALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASLGRGTPV 266 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEH 381 E HG+ G+ + NP A+I + LEH Sbjct: 267 F--EPVHGSAP-----DIAGKGIA-NPTAAILSAAMMLEH 298 >3UDO-A nrPDB Length = 361 Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust. Identities = 57/235 (24%), Positives = 89/235 (37%), Gaps = 65/235 (27%) Query: 224 TDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKI 283 T + I A F+ A +K +++ K +L + +++E+ K D I Sbjct: 165 TKKEIERIARIAFESARIRKKKVHLIDKANVLAS-----SILWREVVANVAK---DYQDI 216 Query: 284 WYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILA----------------QGFGS 326 E+ +D+ Q++K+ F V C N GD+ SD LA +GFG Sbjct: 217 NLEYMYVDNAAMQIVKNPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFG- 275 Query: 327 LGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLD 386 L P G + + AH + NPIA I + L++ K + Sbjct: 276 -------LYEPAGGS-APDIAHLNI--------------ANPIAQILSAALMLKYSFKEE 313 Query: 387 GNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTI 441 + AQ +E + G MTKDL N K +LNT + D I Sbjct: 314 ------QAAQDIENAISLALAQGKMTKDL--------NAK---SYLNTDEMGDCI 351 >4ZDA-A nrPDB Length = 767 Score = 29.3 bits (64), Expect = 3.2, Method: Compositional matrix adjust. Identities = 39/176 (22%), Positives = 64/176 (36%), Gaps = 15/176 (8%) Query: 117 TPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHG 176 T DE ++++ K + + N +R G + R P K R P + H Sbjct: 118 TDDEKKIKDRYAKILGSAVNPVLRE--GNSDRRAPKAVKEYARKHPHSMGEWSQASRTHV 175 Query: 177 DQYKATDF-------VADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESIS 229 K DF DR KMV K G + AG + MY + +++ Sbjct: 176 ATMKTGDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALI 235 Query: 230 GFAHSCFQYAIQKKWPLYMSTKNTILK-----AYDGRFKDIFQEIFDKHYKTDFDK 280 F + A + + K T++K + K +++ F KH K FD+ Sbjct: 236 AFYEEQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKL-FDE 290 >1J10-A nrPDB Length = 516 Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 18/90 (20%) Query: 137 GTIRNILGGTVFREPIICKNIPRLV-------------PGW-TK--PITIGRHAHGDQYK 180 G +++LG T + I+ KN+P + W TK PI + +H + ++ Sbjct: 409 GKFKDLLGVTPVMQTIVVKNVPTTIGDTVYITGNRAELGSWDTKQYPIQLYYDSHSNDWR 468 Query: 181 ATDFV-ADRAGTFKMVFTPKDGSGVKEWEV 209 + A+R FK KDG+ VK W+ Sbjct: 469 GNVVLPAERNIEFKAFIKSKDGT-VKSWQT 497 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5I96-A nrPDB 742 0.0 3US8-A nrPDB 592 e-169 4HCX-A nrPDB 582 e-166 6BL1-B nrPDB 580 e-166 2QFY-A nrPDB 563 e-161 4AOY-A nrPDB 545 e-155 1ZOR-A nrPDB 536 e-153 2UXQ-A nrPDB 528 e-150 2IV0-A nrPDB 302 2e-82 1AI3-A nrPDB 293 8e-80 1HQS-A nrPDB 261 5e-70 1XGV-A nrPDB 245 3e-65 3U1H-A nrPDB 222 2e-58 2D1C-A nrPDB 220 8e-58 1V5B-A nrPDB 217 8e-57 1A05-A nrPDB 205 3e-53 5YVT-A nrPDB 205 5e-53 3VMJ-A nrPDB 203 2e-52 3VML-A nrPDB 203 2e-52 3VMK-A nrPDB 199 2e-51 1CNZ-A nrPDB 196 2e-50 3BLX-A nrPDB 191 6e-49 3TY3-A nrPDB 176 1e-44 Sequences not found previously or not previously below threshold: 3DMS-A nrPDB 260 1e-69 5M2E-A nrPDB 259 2e-69 6C0E-A nrPDB 252 2e-67 2D4V-A nrPDB 242 3e-64 2E5M-A nrPDB 241 5e-64 1CM7-A nrPDB 194 5e-50 1VLC-A nrPDB 186 1e-47 4IWH-A nrPDB 183 2e-46 5J32-A nrPDB 179 1e-45 3BLV-B nrPDB 174 8e-44 3ASJ-A nrPDB 165 3e-41 1WPW-A nrPDB 161 7e-40 1XAD-A nrPDB 160 1e-39 4Y1P-A nrPDB 159 2e-39 3UDO-A nrPDB 159 2e-39 1IDM-A nrPDB 159 3e-39 5GRH-B nrPDB 156 1e-38 5HN5-A nrPDB 153 2e-37 2G4O-A nrPDB 139 3e-33 3FMX-X nrPDB 132 3e-31 2B0T-A nrPDB 46 5e-05 1J1W-A nrPDB 44 9e-05 6G3U-A nrPDB 42 6e-04 5Z16-A nrPDB 42 7e-04 4ZDA-A nrPDB 41 0.001 5KVU-A nrPDB 36 0.026 6IGZ-0 nrPDB 30 2.3 1XDT-T nrPDB 29 4.1 3AI7-A nrPDB 28 6.9 >5I96-A nrPDB Length = 458 Score = 742 bits (1915), Expect = 0.0, Method: Composition-based stats. Identities = 451/452 (99%), Positives = 452/452 (100%) Query: 1 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR 60 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR Sbjct: 1 MAGYLRVVRSLCRASGSRPAWAPAALTAPTSQEQPRRHYADKRIKVAKPVVEMDGDEMTR 60 Query: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE Sbjct: 61 IIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDE 120 Query: 121 ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180 ARVEEFKLKKMWKSPNGTI+NILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK Sbjct: 121 ARVEEFKLKKMWKSPNGTIQNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK 180 Query: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI Sbjct: 181 ATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAI 240 Query: 241 QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS 300 QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS Sbjct: 241 QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS 300 Query: 301 SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK 360 SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK Sbjct: 301 SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK 360 Query: 361 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH 420 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH Sbjct: 361 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH 420 Query: 421 GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452 GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ Sbjct: 421 GLSNVKLNEHFLNTTDFLDTIKSNLDRALGRQ 452 >3US8-A nrPDB Length = 427 Score = 592 bits (1525), Expect = e-169, Method: Composition-based stats. Identities = 281/408 (68%), Positives = 331/408 (81%), Gaps = 7/408 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +IKVA PVVE+DGDEMTRIIWQFIK+KLI P++D+ L+Y+DLG+ NRD TDDQVTID+A Sbjct: 26 KIKVANPVVELDGDEMTRIIWQFIKDKLIHPYLDLDLEYYDLGVENRDATDDQVTIDAAN 85 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A +K+ V VKCATITPDE RVEEFKLKKMWKSPNGTIRNILGG +FREPIICKN+PRLVP Sbjct: 86 AIKKHGVGVKCATITPDEGRVEEFKLKKMWKSPNGTIRNILGGVIFREPIICKNVPRLVP 145 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMY 222 GWTKPI +GRHA GDQY+ATDF G + F +DG + E +VY+ P GV + MY Sbjct: 146 GWTKPIIVGRHAFGDQYRATDFKFPGKGKLSIKFVGEDGQTI-EHDVYDAPGAGVALAMY 204 Query: 223 NTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNK 282 N DESI+ FA + F Y +Q+K P+Y+STKNTILKAYDGRFKDIFQ++FD+ + F K Sbjct: 205 NLDESITEFARASFNYGLQRKVPVYLSTKNTILKAYDGRFKDIFQKVFDEEFAAQFKAEK 264 Query: 283 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 +WYEHRLIDDMVA LK SGG+VWACKNYDGDVQSDI+AQGFGSLGLMTSVL+ PDGKT+ Sbjct: 265 LWYEHRLIDDMVASALKWSGGYVWACKNYDGDVQSDIVAQGFGSLGLMTSVLMTPDGKTV 324 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 EAEAAHGTVTRHYR+HQKG TSTN IASIFAWTRGL HR KLDGN +L +F++ LE+VC Sbjct: 325 EAEAAHGTVTRHYRQHQKGEETSTNSIASIFAWTRGLAHRAKLDGNAELAKFSETLERVC 384 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450 V+TVESG MTKDLA I ++ +L+TT FLD I NL +A+ Sbjct: 385 VDTVESGFMTKDLALLIGP------DQPWLSTTGFLDKIDENLRKAMA 426 >4HCX-A nrPDB Length = 409 Score = 582 bits (1500), Expect = e-166, Method: Composition-based stats. Identities = 266/409 (65%), Positives = 321/409 (78%), Gaps = 7/409 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +IKV+ PVVE+DGDEMTR+IW+ IK+ LILP++DI+L Y+DLG+ +RD TDDQVTID+A Sbjct: 6 KIKVSGPVVELDGDEMTRVIWKLIKDMLILPYLDIRLDYYDLGIEHRDATDDQVTIDAAY 65 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A +K+ V VKCATITPDEARVEEF LKKMW SPNGTIRNILGGT+FREPI+ N+PRLVP Sbjct: 66 AIKKHGVGVKCATITPDEARVEEFNLKKMWLSPNGTIRNILGGTIFREPIVISNVPRLVP 125 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA-GGVGMGM 221 GWTKPI IGRHA GDQY+AT+F D+ GT + FTP DGS E+ + P GGV +GM Sbjct: 126 GWTKPIVIGRHAFGDQYRATNFKVDQPGTVTLTFTPADGSAPIVHEMVSIPEDGGVVLGM 185 Query: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281 YN ESI FA + F Y + KWP+Y+STKNTILKAYDG FKD F+ ++++ +K F+ Sbjct: 186 YNFKESIRDFARASFSYGLNAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAA 245 Query: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + YEHRLIDDMVA LK GG+VWACKNYDGDVQSD +AQG+GSLGLMTSVL+ DGKT Sbjct: 246 GLTYEHRLIDDMVAACLKWEGGYVWACKNYDGDVQSDTVAQGYGSLGLMTSVLMTADGKT 305 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401 +EAEAAHGTVTRHYR++Q G+PTSTNPIASIFAWTRGL+HRGKLDG ++I FA LE V Sbjct: 306 VEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLESV 365 Query: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450 + TVESG MTKDLA I + +LN+ +FLD I NL++ L Sbjct: 366 VIATVESGKMTKDLAILIGP------EQDWLNSEEFLDAIADNLEKELA 408 >6BL1-B nrPDB Length = 425 Score = 580 bits (1494), Expect = e-166, Method: Composition-based stats. Identities = 282/403 (69%), Positives = 330/403 (81%), Gaps = 2/403 (0%) Query: 50 VVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSV 109 VVEM GDEMTRIIW+ IKEKLI P+V++ L +DLG+ NRD T+DQVT D+A A +K++V Sbjct: 10 VVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNV 69 Query: 110 AVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPIT 169 VKCATITPDE RVEEFKLK+MWKSPNGTIRNILGGTVFRE IICKNIPRLV GW KPI Sbjct: 70 GVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPII 129 Query: 170 IGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGMYNTDESI 228 IGRHA+GDQY+ATDFV G ++ +TP DG+ + V+NF GGV MGMYN D+SI Sbjct: 130 IGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSI 189 Query: 229 SGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHR 288 FAHS FQ A+ K WPLY+STKNTILK YDGRFKDIFQEI+DK YK+ F+ KIWYEHR Sbjct: 190 EDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHR 249 Query: 289 LIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAH 348 LIDDMVAQ +KS GGF+WACKNYDGDVQSD +AQG+GSLG+MTSVLVCPDGKT+EAEAAH Sbjct: 250 LIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAH 309 Query: 349 GTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVES 408 GTVTRHYR +QKG+ TSTNPIASIFAWTRGL HR KLD N++L FA LE+V +ET+E+ Sbjct: 310 GTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEA 369 Query: 409 GAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451 G MTKDLA CI GL NV+ ++ +LNT +F+D + NL L + Sbjct: 370 GFMTKDLAACIKGLPNVQRSD-YLNTFEFMDKLGENLKIKLAQ 411 >2QFY-A nrPDB Length = 427 Score = 563 bits (1451), Expect = e-161, Method: Composition-based stats. Identities = 256/414 (61%), Positives = 314/414 (75%), Gaps = 7/414 (1%) Query: 39 YADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTI 98 +A +IKV +PVVE+DGDEMTRIIW IK+KLILP++D+ LKY+DL + +RD T D++T Sbjct: 14 HAFSKIKVKQPVVELDGDEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSDKITQ 73 Query: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158 D+A A +KY V +KCATITPDEARV+EF L KMWKSPNGTIRNILGGTVFREPI+ IP Sbjct: 74 DAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPIVIPRIP 133 Query: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSG--VKEWEVYNFPAGG 216 RLVP W KPI IGRHAHGDQYKATD + G+ ++V+ P D + + +VY++ G Sbjct: 134 RLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYDYKGSG 193 Query: 217 VGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKT 276 V M MYNTDESI GFAHS F+ AI KK L++STKNTILK YDGRFKDIFQE+++ YK+ Sbjct: 194 VAMAMYNTDESIEGFAHSSFKLAIDKKLNLFLSTKNTILKKYDGRFKDIFQEVYEAQYKS 253 Query: 277 DFDKNKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVC 336 F++ I YEHRLIDDMVAQ++KS GGF+ A KNYDGDVQSDI+AQGFGSLGLMTS+LV Sbjct: 254 KFEQLGIHYEHRLIDDMVAQMIKSKGGFIMALKNYDGDVQSDIVAQGFGSLGLMTSILVT 313 Query: 337 PDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQ 396 PDGKT E+EAAHGTVTRHYR++QKG TSTN IASIFAW+RGL RG+LD L +FA Sbjct: 314 PDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKRGELDNTPALCKFAN 373 Query: 397 MLEKVCVETV-ESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449 +LE + TV + G MTKDLA ++ T +FLD ++ L + + Sbjct: 374 ILESATLNTVQQDGIMTKDLALACGNNER----SAYVTTEEFLDAVEKRLQKEI 423 >4AOY-A nrPDB Length = 402 Score = 545 bits (1403), Expect = e-155, Method: Composition-based stats. Identities = 226/405 (55%), Positives = 289/405 (71%), Gaps = 7/405 (1%) Query: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101 +IK+ P+VEMDGDEMTRIIW+ IKE L+ P++++ +Y+DLGL NRD+T+DQVTID+A Sbjct: 2 SKIKMKVPLVEMDGDEMTRIIWRLIKENLLEPYIELNTEYYDLGLENRDKTEDQVTIDAA 61 Query: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161 A QKY V VKCATITP+ RVEE+ LKKMWKSPNGTIR IL GTVFR PI+ +I V Sbjct: 62 RAIQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPIVVNSIKPFV 121 Query: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGM 221 GW KPI+I RHA+GD YK ++ AG ++VFT ++G V ++ F GV MGM Sbjct: 122 KGWKKPISIARHAYGDVYKNVEYYVPSAGKAELVFTSENGE-VSRQTIHEFDGPGVIMGM 180 Query: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281 +NTD+SI FA +CF YA+ L+ STK+TI K YD RFKDIFQEI++ YK F+ Sbjct: 181 HNTDKSIRSFARACFNYALDMNQDLWFSTKDTISKTYDHRFKDIFQEIYENEYKEKFEAK 240 Query: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + Y + LIDD VA++++S GG VWACKNYDGDV SD++A FGSL +MTSVLV PDGK Sbjct: 241 NLQYFYTLIDDAVARIIRSEGGMVWACKNYDGDVMSDMVASAFGSLAMMTSVLVSPDGK- 299 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401 E EAAHGTVTRHY +H KG TSTN +A+IFAWT L+ RG+LDG ++L+ FA LE+ Sbjct: 300 YEFEAAHGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRGELDGIKELVDFATKLEQA 359 Query: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLD 446 V+T+E+G MTKDLA + + +NT DFL I+ + Sbjct: 360 SVQTIENGVMTKDLASL-----SEVPEKKIVNTEDFLKEIRKTFE 399 >1ZOR-A nrPDB Length = 399 Score = 536 bits (1381), Expect = e-153, Method: Composition-based stats. Identities = 214/408 (52%), Positives = 279/408 (68%), Gaps = 10/408 (2%) Query: 42 KRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSA 101 +++KV P+VE+DGDEM R++W+ IKEKLILP++DIQL YFDLG+ RD+TDDQ+TI++A Sbjct: 2 EKVKVKNPIVELDGDEMARVMWKMIKEKLILPYLDIQLVYFDLGIKKRDETDDQITIEAA 61 Query: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLV 161 A +KY V VKCATITPD RV+E+ LKK WKSPN TIR L GTVFR+PI+ KN+P LV Sbjct: 62 KAIKKYGVGVKCATITPDAERVKEYNLKKAWKSPNATIRAYLDGTVFRKPIMVKNVPPLV 121 Query: 162 PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGM 221 W KPI IGRHA+GD Y A + + ++V K+ K V+ F GV M M Sbjct: 122 KRWKKPIIIGRHAYGDIYNAVEAKVEGPAEVELVVRNKEN---KTLLVHKFEGNGVVMAM 178 Query: 222 YNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKN 281 +N ++SI FA SC YAI +K ++ +TK+TI K Y FKDIFQE DK K + +K Sbjct: 179 HNLEKSIRSFAQSCINYAISEKVDIWFATKDTISKVYHAYFKDIFQEEVDKR-KEELEKA 237 Query: 282 KIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKT 341 + Y + LIDD AQ+L+S GG +WAC NY+GD+ SD++A GFGSLGLMTSVLV PDG Sbjct: 238 GVNYRYMLIDDAAAQILRSEGGMLWACMNYEGDIMSDMIASGFGSLGLMTSVLVSPDG-V 296 Query: 342 IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKV 401 E EAAHGTV RHY + KG TSTNP ASIFAWT + RG+LDG ++ FA LEK Sbjct: 297 YEFEAAHGTVRRHYYRYLKGEKTSTNPTASIFAWTGAIRKRGELDGTPEVCEFADKLEKA 356 Query: 402 CVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449 + T+ESG +TKDL + ++ ++ +F+D +K NL++ L Sbjct: 357 VINTIESGVITKDL----QPFTEPPID-KYVTLEEFIDEVKKNLEKLL 399 >2UXQ-A nrPDB Length = 402 Score = 528 bits (1360), Expect = e-150, Method: Composition-based stats. Identities = 199/406 (49%), Positives = 274/406 (67%), Gaps = 7/406 (1%) Query: 43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL 102 +I++ P+VE+DGDEMTR++W IK+KL+LP +D+Q +Y+DLG+ RD+T+DQ+TID+A Sbjct: 2 KIQMKTPLVELDGDEMTRVLWPLIKDKLLLPFIDLQTEYYDLGIEERDRTNDQITIDAAE 61 Query: 103 ATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVP 162 A +KY V VK ATITP++ RVEE+ LK+ WKSPN T+R +L GTVFR+PI+ KNI V Sbjct: 62 AIKKYGVGVKNATITPNQDRVEEYGLKEQWKSPNATVRAMLDGTVFRKPIMVKNIKPSVR 121 Query: 163 GWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMY 222 W KPI +GRHA+GD YK + A+ G ++V T K+G ++ + + G++ Sbjct: 122 SWQKPIVVGRHAYGDFYKNAEIFAEAGGKLEIVVTDKNGKETRQ-TIMEVDEPAIVQGIH 180 Query: 223 NTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNK 282 NT SI FA +CF+Y++ +K + +TK+TI K YD RFK IF+EIF + YK F Sbjct: 181 NTVASIGHFARACFEYSLDQKIDCWFATKDTISKQYDQRFKIIFEEIFAQEYKEKFAAAG 240 Query: 283 IWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 I Y + LIDD+VA+++K+ GG +WACKNYDGDV SD++A FGSL +M+SVLV P G Sbjct: 241 IEYFYTLIDDVVARMMKTEGGMLWACKNYDGDVMSDMVASAFGSLAMMSSVLVSPYG-YF 299 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 E EAAHGTV RHY +H KG TSTNP+A I+AWT L RG+LDG DL F LE + Sbjct: 300 EYEAAHGTVQRHYYQHLKGERTSTNPVALIYAWTGALRKRGELDGTPDLCAFCDSLEAIT 359 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRA 448 +E +ESG MT DLA + L++ +F+D + L + Sbjct: 360 IECIESGYMTGDLARICEPAAI-----KVLDSIEFIDELGKRLQQL 400 >2IV0-A nrPDB Length = 412 Score = 302 bits (774), Expect = 2e-82, Method: Composition-based stats. Identities = 82/367 (22%), Positives = 141/367 (38%), Gaps = 58/367 (15%) Query: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII-CKNI 157 D+ A +++ VA+K TP + ++S N TIR +L P+ K + Sbjct: 83 DTLNAIKEFRVALKGPLTTP---------VGGGYRSLNVTIRQVLDLYANVRPVYYLKGV 133 Query: 158 PRLVPGWTK-PITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGG 216 P + K I R D Y ++ K++ K+ GV E Sbjct: 134 PSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEFGVTIRE-------D 186 Query: 217 VGMGMYNTDE-SISGFAHSCFQYAI-QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKH- 273 G+G+ E + +YAI + + + K I+K +G F+D E+ + Sbjct: 187 SGIGIKPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQEF 246 Query: 274 -------------YKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDI 319 Y + KI + R+ D+M Q+L + + V A N +GD SD Sbjct: 247 GEYCITEDELWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYDVIALPNLNGDYLSDA 306 Query: 320 LAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGL 379 A G LG+ + DG + E HG+ ++ +++ NP A I Sbjct: 307 AAALIGGLGIAPGSNIG-DGIGV-FEPVHGSAPKYAGQNK------VNPTAEILTGALMF 358 Query: 380 EHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLD 439 E+ G D ++M++K T+ SG +T D+ + G + T +F + Sbjct: 359 EYIGWKDA-------SEMIKKAVEMTISSGIVTYDIHRHMGGTK--------VGTREFAE 403 Query: 440 TIKSNLD 446 + NL Sbjct: 404 AVVENLQ 410 >1AI3-A nrPDB Length = 416 Score = 293 bits (751), Expect = 8e-80, Method: Composition-based stats. Identities = 92/442 (20%), Positives = 165/442 (37%), Gaps = 71/442 (16%) Query: 47 AKPVVEMDGDEMTRIIWQF-IKEKLILPHVDIQ----------LKYFDLGLPNRDQTDDQ 95 +K VV G ++T + + E I+P+++ LK D + + + + Sbjct: 3 SKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERK 62 Query: 96 VT----IDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSP-NGTIRNILGGTVFRE 150 ++ +TQ Y V T D R +K +P G IR++ R+ Sbjct: 63 ISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSL--NVALRQ 120 Query: 151 PI---ICKNIPRLVPGWTKPI--------TIGRHAHGDQYKATDFVADRAGTFKMVFTPK 199 + IC R G P+ I R D Y ++ AD A K++ + Sbjct: 121 ELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIYAGIEWKADSADAEKVIKFLR 180 Query: 200 DGSGVKEWEVYNFPAGGVGMGMYN-TDESISGFAHSCFQYAI-QKKWPLYMSTKNTILKA 257 + GVK+ FP G+G+ ++E + +YAI + + + K I+K Sbjct: 181 EEMGVKK---IRFPEH-CGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKF 236 Query: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYE-------------HRLIDDMVAQVLKSSGGF 304 +G FKD ++ + + + W + + D + Q+L + Sbjct: 237 TEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEY 296 Query: 305 -VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRP 363 V AC N +GD SD LA G +G+ + + EA HGT ++ + + Sbjct: 297 DVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL--FEATHGTAPKYAGQDK---- 350 Query: 364 TSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLS 423 NP + I + L H G + A ++ K + + +T D + G Sbjct: 351 --VNPGSIILSAEMMLRHMGWTEA-------ADLIVKGMEGAINAKTVTYDFERLMDGAK 401 Query: 424 NVKLNEHFLNTTDFLDTIKSNL 445 +K + +F D I N+ Sbjct: 402 LLKCS-------EFGDAIIENM 416 >1HQS-A nrPDB Length = 423 Score = 261 bits (666), Expect = 5e-70, Method: Composition-based stats. Identities = 88/443 (19%), Positives = 156/443 (35%), Gaps = 82/443 (18%) Query: 48 KPVVE-MDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQK 106 P++ ++GD IW + L + + + + ++T A +K Sbjct: 19 NPIIPFIEGDGTGPDIWNAASKVL------------EAAVEKAYKGEKKITWKEVYAGEK 66 Query: 107 --YSVAVKCATITPDEARVEEFKLKKMWKSP-NGTIRNILGGTVFREPI---ICKNIPRL 160 T D R +K +P G IR++ R+ + +C R Sbjct: 67 AYNKTGEWLPAETLDVIREYFIAIKGPLTTPVGGGIRSL--NVALRQELDLFVCLRPVRY 124 Query: 161 VPGWTKPI--------TIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNF 212 G P+ I R D Y ++ K++ ++ V + F Sbjct: 125 FTGVPSPVKRPEDTDMVIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNK---IRF 181 Query: 213 PAGGVGMGMYN-TDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIF 270 P G+G+ ++E S + YAI+ + + + K I+K +G FK+ E+ Sbjct: 182 PETS-GIGIKPVSEEGTSRLVRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELA 240 Query: 271 DKHYKTDF--------------------------DKNKIWYEHRLIDDMVAQVLKSSGGF 304 +K Y KI + + D + Q+L F Sbjct: 241 EKEYGDKVFTWAQYDRIAEEQGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEF 300 Query: 305 -VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRP 363 V A N +GD SD LA G +G+ + + EA HGT ++ + Sbjct: 301 DVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDK---- 356 Query: 364 TSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLS 423 NP + I + LEH G + A ++ K +T+ S +T D A + G + Sbjct: 357 --VNPSSVILSGVLLLEHLGWNEA-------ADLVIKSMEKTIASKVVTYDFARLMDGAT 407 Query: 424 NVKLNEHFLNTTDFLDTIKSNLD 446 VK + +F + + N+D Sbjct: 408 EVKCS-------EFGEELIKNMD 423 >3DMS-A nrPDB Length = 427 Score = 260 bits (663), Expect = 1e-69, Method: Composition-based stats. Identities = 81/414 (19%), Positives = 150/414 (36%), Gaps = 59/414 (14%) Query: 66 IKEKLILPHVDIQLKYFDLG---LPNRDQTDDQ----------VTIDSAL-ATQKYSVAV 111 + ++ I+P+++ FD+ + D ++ + I + AT+ Y V Sbjct: 33 VSDQPIIPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKIHWMEIYAGEKATKVYGPDV 92 Query: 112 KCATITPDEARVEEFKLKKMWKSP-NGTIRNI-------LGGTVFREPI-ICKNIPRLVP 162 T + +K +P G IR++ L V PI K +P V Sbjct: 93 WLPEETLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPIQYFKGVPSPVR 152 Query: 163 GWTK-PITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGM 221 K + I R D Y ++ A+ K++ ++ GVK+ FP G+G+ Sbjct: 153 EPEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEMGVKK---IRFPQTS-GIGI 208 Query: 222 YN-TDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFD 279 + E QYAI + + + K I+K +G F+D + K + + Sbjct: 209 KPVSKEGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRDAGYALAQKEFGAELI 268 Query: 280 KNKIW-------------YEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFG 325 W + + D + Q+L + V A N +GD SD LA G Sbjct: 269 DGGPWMKFKNPKTGNEIVVKDSIADAFLQQILLRPAEYDVIATLNLNGDYISDALAAQVG 328 Query: 326 SLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKL 385 +G+ + EA HGT ++ + NP + I + L H G Sbjct: 329 GIGIAPGANLSD--SVAMFEATHGTAPKYAGKD------YVNPGSEILSAEMMLRHLGWT 380 Query: 386 DGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLD 439 + A ++ ++++ +T D A + G + V + + ++ Sbjct: 381 EA-------ADVIISAMEKSIKQKRVTYDFARLMEGATQVSCSGFGQVLIENME 427 >5M2E-A nrPDB Length = 418 Score = 259 bits (662), Expect = 2e-69, Method: Composition-based stats. Identities = 75/372 (20%), Positives = 131/372 (35%), Gaps = 56/372 (15%) Query: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSP-NGTIRNILGGTVFREPI---ICKNI 157 ATQ Y T D R +K +P G IR++ R+ + +C+ Sbjct: 75 KATQVYDQDTWLPQETLDAVRDYVVSIKGPLTTPVGGGIRSL--NVALRQQLDLYVCQRP 132 Query: 158 PRLVPGWTKPI--------TIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEV 209 R G P+ I R D Y ++ A K++ + GVK+ Sbjct: 133 VRWFEGVPSPVKKPGDVDMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKK--- 189 Query: 210 YNFPAGGVGMGMYN-TDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQ 267 F G+G+ + E QYA+ + + + K I+K +G FKD Sbjct: 190 IRFTEN-CGIGIKPVSQEGTKRLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGY 248 Query: 268 EIFDKHYKTDFDKNKIW-------------YEHRLIDDMVAQVLKSSGGF-VWACKNYDG 313 E+ + + W + + D M+ Q+L + V A N +G Sbjct: 249 EVARDEFGAELLDGGPWMQFKNPKTGKNVVVKDVIADAMLQQILLRPAEYDVIATLNLNG 308 Query: 314 DVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIF 373 D SD LA G +G+ + EA HGT ++ + + NP + I Sbjct: 309 DYLSDALAAEVGGIGIAPGANLSD--SVAMFEATHGTAPKYAGQDK------VNPGSLIL 360 Query: 374 AWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLN 433 + L H G + A ++ K + + +T D + G + + + Sbjct: 361 SAEMMLRHMGWTEA-------ADLIIKGTNGAIAAKTVTYDFERLMDGATLLSCS----- 408 Query: 434 TTDFLDTIKSNL 445 +F D + + + Sbjct: 409 --EFGDAMIAKM 418 >6C0E-A nrPDB Length = 419 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 78/371 (21%), Positives = 139/371 (37%), Gaps = 53/371 (14%) Query: 93 DDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPI 152 D + ++ A +KY V++K TP + +S N IR + V PI Sbjct: 84 DQWLPKETLDAMKKYVVSIKGPLTTP---------VGGGIRSLNVAIRQDMDLYVCLRPI 134 Query: 153 -ICKNIPRLVPG-WTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVY 210 +P V W + I R D Y ++ AD K++ GVK+ Sbjct: 135 RYFNGVPSPVREPWKTDMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKK---I 191 Query: 211 NFPAGGVGMGMYN-TDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQE 268 FP G+G+ + E + + QYAI + + + K I+K +G FKD + Sbjct: 192 RFPEH-CGIGVKPVSREGTTRLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQ 250 Query: 269 IFDKHYKTDFDKNKIWYE-------------HRLIDDMVAQVLKSSGGF-VWACKNYDGD 314 + + + W E + D + Q+L + V A N +GD Sbjct: 251 VARDSFGAKEYQGGPWMEFKNPKTGKQIIINDVIADAFLQQILLRPEDYSVIATLNLNGD 310 Query: 315 VQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFA 374 SD LA G +G+ + EA HGT ++ +++ NP + I + Sbjct: 311 YISDALAAQVGGIGIAPGANISDQMAV--FEATHGTAPKYAGQNK------VNPGSIILS 362 Query: 375 WTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNT 434 L H G + A ++ + +E+ +T D + G + +++ Sbjct: 363 AEMMLRHMGWYEA-------ADLIIRGMEGAIEAKTVTYDFERGMQGAT-------LVSS 408 Query: 435 TDFLDTIKSNL 445 + F D + ++ Sbjct: 409 SGFADAMIKHM 419 >1XGV-A nrPDB Length = 435 Score = 245 bits (625), Expect = 3e-65, Method: Composition-based stats. Identities = 68/374 (18%), Positives = 139/374 (37%), Gaps = 48/374 (12%) Query: 89 RDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVF 148 R++ + + + + VA+K TP + ++S N IR L Sbjct: 84 REKCGELLPKATLEGIRLARVALKGPLETP---------VGTGYRSLNVAIRQALDLYAN 134 Query: 149 REPIICKNIPRLVPGWTK-PITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEW 207 P+ P + + I R D Y ++ D ++ + G+ Sbjct: 135 IRPVRYYGQPAPHKYADRVDMVIFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIR 194 Query: 208 EVYNFPAGGVGMGMYN-TDESISGFAHSCFQYAIQKKWPL-YMSTKNTILKAYDGRFKDI 265 E G+G+ + + ++A++ + + K I+K +G F Sbjct: 195 E-------DAGIGVKPISRFATRRLMERALEWALRNGNTVVTIMHKGNIMKYTEGAFMRW 247 Query: 266 FQEIF--------------DKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKN 310 E+ + Y + KI R+ D+M+ Q++ + V N Sbjct: 248 AYEVALEKFREHVVTEQEVQEKYGGVRPEGKILVNDRIADNMLQQIITRPWDYQVIVAPN 307 Query: 311 YDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIA 370 +GD SD + G +G+ + + DG + AE HGT ++ + NP A Sbjct: 308 LNGDYISDAASALVGGIGMAAGMNMG-DGIAV-AEPVHGTAPKYAGKDL------INPSA 359 Query: 371 SIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEH 430 I + + + G+ G +++ ++E + V+S +T+DLA + G+ ++ +E+ Sbjct: 360 EILSASLLI---GEFMGWREV---KSIVEYAIRKAVQSKKVTQDLARHMPGVQPLRTSEY 413 Query: 431 FLNTTDFLDTIKSN 444 ++D N Sbjct: 414 TETLIAYIDEADLN 427 >2D4V-A nrPDB Length = 429 Score = 242 bits (617), Expect = 3e-64, Method: Composition-based stats. Identities = 76/385 (19%), Positives = 131/385 (34%), Gaps = 69/385 (17%) Query: 102 LATQKYSVAVKCATITPDEARVEEFKLKKMWKSP-NGTIRNILGGTVFREPI---ICKNI 157 A Q Y T R + +K ++P G IR++ R+ + +C Sbjct: 73 KAVQLYGEGQYLPDETMAAIREYKVAIKGPLETPVGGGIRSL--NVAMRQDLDLYVCLRP 130 Query: 158 PRLVPGWTKPI--------TIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEV 209 R G P+ I R D Y ++ A K++ ++ GV + Sbjct: 131 VRYFEGTPSPMRHPEKVDMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLREEMGVTK--- 187 Query: 210 YNFPAGGVGMGMYN-TDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQ 267 FP +G+ + E QYA++ K + + K I+K +G F+D Sbjct: 188 IRFPDSS-AIGIKPVSTEGSERLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGY 246 Query: 268 EIFDKHYKTD--------------------------FDKNKIWYEHRLIDDMVAQVLKSS 301 + ++ + K+ + + D+ + Q+L Sbjct: 247 ALAEREFAGRVFTWRQKAAISKAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRP 306 Query: 302 GGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK 360 + V A N +GD SD LA G +G+ + EA HGT + + Sbjct: 307 EDYSVVATLNLNGDYVSDALAAEVGGIGMAPGANLSDT--HAIFEATHGTAPDIAGQGK- 363 Query: 361 GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIH 420 NP + I + LEH G + AQ + T+ +G +T DLA Sbjct: 364 -----ANPSSLILSAVMMLEHLGWGEA-------AQAIVAAMNATIAAGEVTGDLAALRG 411 Query: 421 GLSNVKLNEHFLNTTDFLDTIKSNL 445 + L+TT+F + Sbjct: 412 DVPA-------LSTTEFTAALIRRF 429 >2E5M-A nrPDB Length = 409 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 73/369 (19%), Positives = 135/369 (36%), Gaps = 53/369 (14%) Query: 93 DDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPI 152 +D+ ++ KY V +K TP + K WKS N IR +L P+ Sbjct: 77 NDRFPKETQEMLLKYRVVLKGPLETP---------IGKGWKSVNVAIRLMLDLYANIRPV 127 Query: 153 -ICKNIPRLVPGWTK-PITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVY 210 + + + K + I R D Y+ ++ + K+ + V E+ Sbjct: 128 KYIEGLESPLKHPEKVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKELKV---EIE 184 Query: 211 NFPAGGVGMGMYNTDESISGFAHSCFQYAI-QKKWPLYMSTKNTILKAYDGRFKDIFQEI 269 + G+ + QYAI K+ + + K ++K +G F++ E+ Sbjct: 185 DDTGIGIKVMSKY---KTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYEV 241 Query: 270 FDKHYK-----------TDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQS 317 K Y+ D+ KI R+ D+M Q++ + + N +GD S Sbjct: 242 ALKEYRDFIVTEEEINQGKPDQGKIILNDRIADNMFQQIIIRPEEYDIILAPNVNGDYIS 301 Query: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377 D G++G++ + +G EA HGT ++ ++ NP I A Sbjct: 302 DAAGALIGNIGMLGGANIGDEGG--MFEAIHGTAPKYAGKN------VANPTGIIKAGEL 353 Query: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 437 L G + A ++EK + +T+D+A + L T ++ Sbjct: 354 MLRWMGWNEA-------ADLIEKAINMAIRDKKVTQDIARFMG--------VKALGTKEY 398 Query: 438 LDTIKSNLD 446 D + +D Sbjct: 399 ADELIKIMD 407 >3U1H-A nrPDB Length = 390 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 62/315 (19%), Positives = 118/315 (37%), Gaps = 50/315 (15%) Query: 138 TIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF- 196 IR L P+ + K + + D V R T + F Sbjct: 115 GIRKGLDLFANLRPVKVYDSLADASPLKKEVI----------EGVDLVIVRELTGGLYFG 164 Query: 197 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILK 256 P + E + + T E I F+ A+ +K + K +L+ Sbjct: 165 EPSERYEEGEEAAVDT--------LLYTREEIERIIRKAFELALTRKKKVTSVDKANVLE 216 Query: 257 AYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDV 315 + ++++ +E+ ++ + EH L+D+ Q++++ F V +N GD+ Sbjct: 217 SSR-LWREVAEEVAKEY-------PDVELEHMLVDNAAMQLIRNPRQFDVIVTENMFGDI 268 Query: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375 SD + GSLG++ S + DG + E HG+ + NP+A+I + Sbjct: 269 LSDEASMITGSLGMLPSASLSTDGLGL-YEPVHGSAPDIAGKGI------ANPLATILSA 321 Query: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTT 435 L + L+ A+ +EK + + G T D+A K +++TT Sbjct: 322 AMMLRYSFGLE------EEAKAIEKAVEKVLAEGYRTADIA---------KPGGKYVSTT 366 Query: 436 DFLDTIKSNLDRALG 450 + D +K+ + L Sbjct: 367 EMTDEVKAAVVDELA 381 >2D1C-A nrPDB Length = 496 Score = 220 bits (561), Expect = 8e-58, Method: Composition-based stats. Identities = 66/356 (18%), Positives = 129/356 (36%), Gaps = 71/356 (19%) Query: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII-C 154 V ++ + +K V +K TP + KS N T+R + P+ Sbjct: 69 VPQETIESIRKTRVVLKGPLETP---------VGYGEKSANVTLRKLFETYANVRPVREF 119 Query: 155 KNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA 214 N+P G + + R D Y + + S + ++ ++ Sbjct: 120 PNVPTPYAGRGIDLVVVRENVEDLYAGIE-------------HMQTPSVAQTLKLISWKG 166 Query: 215 GGVGMGMYNTDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIFDKH 273 F+ A + + ++ +TK+ I+K +G K F+++ ++ Sbjct: 167 S-------------EKIVRFAFELARAEGRKKVHCATKSNIMKLAEGTLKRAFEQVAQEY 213 Query: 274 YKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTS 332 I H ++D+ Q++K F V N +GD+ SD+ + G LG S Sbjct: 214 -------PDIEAVHIIVDNAAHQLVKRPEQFEVIVTTNMNGDILSDLTSGLIGGLGFAPS 266 Query: 333 VLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLI 392 + + EA HG+ ++ ++ NP A + + L + + Sbjct: 267 ANIGNEVAI--FEAVHGSAPKYAGKN------VINPTAVLLSAVMMLRYLEEF------- 311 Query: 393 RFAQMLEKVCVETVESG-AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDR 447 A ++E + T+E G +T D+ G G TT++ + I NL + Sbjct: 312 ATADLIENALLYTLEEGRVLTGDVVGYDRG----------AKTTEYTEAIIQNLGK 357 >1V5B-A nrPDB Length = 366 Score = 217 bits (552), Expect = 8e-57, Method: Composition-based stats. Identities = 68/348 (19%), Positives = 125/348 (35%), Gaps = 46/348 (13%) Query: 110 AVKCATITPDEARVEEFKLKKM-----WKSPNGTIRNILGGTVFREPIICKNIPRLVPGW 164 T D R + L W ++R G R+ + R V + Sbjct: 52 GTPLPEETLDICRRSDAILLGAVGGPKWDHNPASLRPEKGLLGLRKEMGLFANLRPVKAY 111 Query: 165 TKPITIGRHAHGDQYKATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYN 223 + ++ + D V R T + F P + G E EV + + Sbjct: 112 AT-LLNASPLKRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDT--------LAY 162 Query: 224 TDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKI 283 T E I FQ A ++ L K +L++ +++I +E K+ + Sbjct: 163 TREEIERIIEKAFQLAQIRRKKLASVDKANVLESSR-MWREIAEETAKKY-------PDV 214 Query: 284 WYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTI 342 H L+D Q++ + G F V +N GD+ SD+ + GSLG++ S + D + Sbjct: 215 ELSHMLVDSTAMQLIANPGQFDVIVTENMFGDILSDLASVITGSLGMLPSASLRSDRFGM 274 Query: 343 EAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVC 402 E HG+ + + NP+ ++ + L + L+ + A +EK Sbjct: 275 -YEPVHGSAPDIAGQGK------ANPLGTVLSAALMLRYSFGLE------KEAAAIEKAV 321 Query: 403 VETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALG 450 + ++ G T DL N ++T + D + L+ + Sbjct: 322 DDVLQDGYCTGDL---------QVANGKVVSTIELTDRLIEKLNNSAA 360 >1A05-A nrPDB Length = 358 Score = 205 bits (522), Expect = 3e-53, Method: Composition-based stats. Identities = 54/257 (21%), Positives = 102/257 (39%), Gaps = 29/257 (11%) Query: 177 DQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCF 236 + + D + R T + F + EV + G +Y+ DE I AH F Sbjct: 122 ELVRDVDILVVRELTGDIYF-----GQPRGLEVIDGKRRGFNTMVYDEDE-IRRIAHVAF 175 Query: 237 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 296 + A ++ L K +L+ ++++ E+ D + H +D+ Q Sbjct: 176 RAAQGRRKQLCSVDKANVLETTR-LWREVVTEVAR-------DYPDVRLSHMYVDNAAMQ 227 Query: 297 VLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355 ++++ F V N GD+ SD +Q GS+G++ S + +G+ + E HG+ Sbjct: 228 LIRAPAQFDVLLTGNMFGDILSDEASQLTGSIGMLPSASLG-EGRAM-YEPIHGSAPDIA 285 Query: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415 + + NP+A+I + L H L+ +AQ +E ++ G T D+ Sbjct: 286 GQDK------ANPLATILSVAMMLRHS--LNAEP----WAQRVEAAVQRVLDQGLRTADI 333 Query: 416 AGCIHGLSNVKLNEHFL 432 A + K + Sbjct: 334 AAPGTPVIGTKAMGAAV 350 >5YVT-A nrPDB Length = 339 Score = 205 bits (520), Expect = 5e-53, Method: Composition-based stats. Identities = 72/372 (19%), Positives = 116/372 (31%), Gaps = 84/372 (22%) Query: 87 PNRDQTDDQ-------VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTI 139 R+ T Q + ++ + K + +K TP + S N + Sbjct: 37 EERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTP---------IAAGHPSMNLLL 87 Query: 140 RNILGGTVFREPIICKNIPRL-VPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTP 198 R P C +I P I R +Y + V Sbjct: 88 RKTFDLYANVRP--CVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIV----------- 134 Query: 199 KDGSGVKEWEVYNFPAGGVGMGMYNTDESIS-GFAHSCFQYAIQK-KWPLYMSTKNTILK 256 GV + E S A F+YA + + K I++ Sbjct: 135 ----------------DGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMR 178 Query: 257 AYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDV 315 DG F +E+ + F++ +D + +++ F V N GD+ Sbjct: 179 MSDGLFLQKCREVAESCKDIKFNE-------MYLDTVCLNMVQDPSQFDVLVMPNLYGDI 231 Query: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375 SD+ A G LG+ S + +G I E+ HGT + NP A + + Sbjct: 232 LSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAPDIAGKDM------ANPTALLLSA 284 Query: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGA-MTKDLAGCIHGLSNVKLNEHFLNT 434 L H G D A +E C T++ G +TKDL G Sbjct: 285 VMMLRHMGLFD-------HAARIEAACFATIKDGKSLTKDLGGN-------------AKC 324 Query: 435 TDFLDTIKSNLD 446 +DF + I + Sbjct: 325 SDFTEEICRRVK 336 >3VMJ-A nrPDB Length = 375 Score = 203 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 58/238 (24%), Positives = 93/238 (39%), Gaps = 30/238 (12%) Query: 180 KATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQY 238 + D + R T + F PK G E E M + IS A F+ Sbjct: 139 RGFDVLCVRELTGGIYFGKPKGRQGEGESE-------EAFDTMRYSRREISRIARIAFEA 191 Query: 239 AIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVL 298 A ++ + K +L A ++ + +E+ D + EH ID+ Q+L Sbjct: 192 ARGRRKKVTSVDKANVL-ACSVLWRQVVEEVA-------VDFPDVELEHIYIDNATMQLL 243 Query: 299 KSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRE 357 + F V C N GD+ SD +A GS+GL++S + G + E A G+ + Sbjct: 244 RRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGL-FEPAGGSAPDIAGK 302 Query: 358 HQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415 NPIA I + L H K + A +E+ + + SG +T +L Sbjct: 303 GI------ANPIAQILSAALMLRHSLKQE------EAASAIERAVTKALNSGYLTGEL 348 >3VML-A nrPDB Length = 375 Score = 203 bits (515), Expect = 2e-52, Method: Composition-based stats. Identities = 58/238 (24%), Positives = 94/238 (39%), Gaps = 30/238 (12%) Query: 180 KATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQY 238 K D + R T + F PK G E E M + + I A F+ Sbjct: 139 KGFDILCVRELTGGIYFGKPKGRQGEGENE-------EAFDTMRYSRKEIRRIAKIAFES 191 Query: 239 AIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVL 298 A ++ + K +L A ++++ +E+ D + EH ID+ Q+L Sbjct: 192 AQGRRKKVTSVDKANVL-ACSVLWREVVEEVAK-------DYPDVELEHIYIDNATMQLL 243 Query: 299 KSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRE 357 + F V C N GD+ SD +A GS+GL+ S+ + G + E A G+ + Sbjct: 244 RRPNEFDVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGM-YEPAGGSAPDIAGQ 302 Query: 358 HQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415 NP+A I + L H KL+ A +E + + SG +T +L Sbjct: 303 GI------ANPVAQILSAALLLRHSLKLE------DAALAIEAAVSKALNSGYLTGEL 348 >3VMK-A nrPDB Length = 375 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 57/238 (23%), Positives = 93/238 (39%), Gaps = 30/238 (12%) Query: 180 KATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQY 238 K D + R T + F PK G E E M + + I A F+ Sbjct: 139 KGFDILCVRELTGGIYFGKPKGRQGEGENE-------EAFDTMRYSRKEIRRIAKIAFES 191 Query: 239 AIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVL 298 A ++ + K +L A ++++ +E+ D + EH ID+ Q+L Sbjct: 192 AQGRRKKVTSVDKANVL-ACSVLWREVVEEVAK-------DYPDVELEHIYIDNATMQLL 243 Query: 299 KSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRE 357 + F V C N GD+ SD +A GS+GL+ S+ + G + E A G+ + Sbjct: 244 RRPNEFDVMLCSNLFGDIVSDEIAMLTGSMGLLASISMNSQGFGM-YEPAGGSAPDIAGQ 302 Query: 358 HQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDL 415 NP+A I + L H KL+ A +E + + G +T +L Sbjct: 303 GI------ANPVAQILSAALLLRHSLKLE------DAALAIEAAVSKALSDGYLTCEL 348 >1CNZ-A nrPDB Length = 363 Score = 196 bits (497), Expect = 2e-50, Method: Composition-based stats. Identities = 56/240 (23%), Positives = 92/240 (38%), Gaps = 30/240 (12%) Query: 180 KATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQY 238 D + R T + F PK G ++E +Y+ I A F+ Sbjct: 130 NGFDILCVRELTGGIYFGQPKGREGSGQYE------KAFDTEVYH-RFEIERIARIAFES 182 Query: 239 AIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVL 298 A +++ + K +L++ +++EI + KT + H ID+ Q++ Sbjct: 183 ARKRRRKVTSIDKANVLQSS-----ILWREIVNDVAKT---YPDVELAHMYIDNATMQLI 234 Query: 299 KSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRE 357 K F V C N GD+ SD A GS+G++ S + G + E A G+ + Sbjct: 235 KDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAPDIAGK 293 Query: 358 HQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAG 417 + NPIA I + L + D A +E+ +E G T DLA Sbjct: 294 NI------ANPIAQILSLALLLRYSL------DANDAATAIEQAINRALEEGVRTGDLAR 341 >1CM7-A nrPDB Length = 363 Score = 194 bits (493), Expect = 5e-50, Method: Composition-based stats. Identities = 55/240 (22%), Positives = 92/240 (38%), Gaps = 30/240 (12%) Query: 180 KATDFVADRAGTFKMVF-TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQY 238 D + R T + F PK G ++E +Y+ I A F+ Sbjct: 130 NGFDILCVRELTGGIYFGQPKGREGSGQYE------KAFDTEVYH-RFEIERIARIAFES 182 Query: 239 AIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVL 298 A +++ + K +L++ +++I EI ++ + H ID+ Q++ Sbjct: 183 ARKRRHKVTSIDKANVLQSS-ILWREIVNEIATEY-------PDVELAHMYIDNATMQLI 234 Query: 299 KSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRE 357 K F V C N GD+ SD A GS+G++ S + G + E A G+ + Sbjct: 235 KDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGL-YEPAGGSAPDIAGK 293 Query: 358 HQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAG 417 + NPIA I + L + D A +E+ +E G T DLA Sbjct: 294 NI------ANPIAQILSLALLLRYSLDAD------DAACAIERAINRALEEGIRTGDLAR 341 >3BLX-A nrPDB Length = 349 Score = 191 bits (484), Expect = 6e-49, Method: Composition-based stats. Identities = 67/351 (19%), Positives = 109/351 (31%), Gaps = 73/351 (20%) Query: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPI-ICKNI 157 ++ + ++ + +K TP + S N +R L K + Sbjct: 65 EAVESLKRNKIGLKGLWHTPADQT--------GHGSLNVALRKQLDIYANVALFKSLKGV 116 Query: 158 PRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGV 217 +P + + R ++ + S E Sbjct: 117 KTRIPDID--LIVIRENTEGEFSGLE----------------HESVPGVVESLKVM---- 154 Query: 218 GMGMYNTDESISGFAHSCFQYAIQ-KKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKT 276 T A F +A + + + K I+K DG F++I EI K Y Sbjct: 155 ------TRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLFRNIITEIGQKEY-- 206 Query: 277 DFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLV 335 I ++D+ Q + F V + G + +I A G GL+ Sbjct: 207 ----PDIDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPGLVAGANF 262 Query: 336 CPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395 D E +RH KG+ NP A I + T L H G L +A Sbjct: 263 GRDYAVFEPG------SRHVGLDIKGQNV-ANPTAMILSSTLMLNHLG-------LNEYA 308 Query: 396 QMLEKVCVETVESGA-MTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445 + K ET+ G T+D+ G +TTDF + I + L Sbjct: 309 TRISKAVHETIAEGKHTTRDIGGS-------------SSTTDFTNEIINKL 346 >1VLC-A nrPDB Length = 366 Score = 186 bits (473), Expect = 1e-47, Method: Composition-based stats. Identities = 59/310 (19%), Positives = 108/310 (34%), Gaps = 52/310 (16%) Query: 139 IRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTP 198 +R +L PI V K IG D V R ++ + + Sbjct: 106 LRKMLNLYANIRPIKVYRSLVHV-SPLKEKVIG--------SGVDLVTVRELSYGVYY-- 154 Query: 199 KDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAY 258 + + G +Y+ +++ A + F+ A ++ + K +L Sbjct: 155 ---GQPRGLD----EEKGFDTMIYD-RKTVERIARTAFEIAKNRRKKVTSVDKANVL-YS 205 Query: 259 DGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQS 317 ++ + E+ ++ + H +D+ Q++ F V N GD+ S Sbjct: 206 SMLWRKVVNEVAREY-------PDVELTHIYVDNAAMQLILKPSQFDVILTTNMFGDILS 258 Query: 318 DILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTR 377 D A GSLGL+ S E A G+ ++ NPIA I + Sbjct: 259 DESAALPGSLGLLPSASFGDKNL---YEPAGGSAPDIAGKNI------ANPIAQILSLAM 309 Query: 378 GLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDF 437 LEH ++ A+ +E+ +E G T+D+A + E ++T+ Sbjct: 310 MLEHSFG------MVEEARKIERAVELVIEEGYRTRDIA---------EDPEKAVSTSQM 354 Query: 438 LDTIKSNLDR 447 D I L+ Sbjct: 355 GDLICKKLEE 364 >4IWH-A nrPDB Length = 363 Score = 183 bits (464), Expect = 2e-46, Method: Composition-based stats. Identities = 59/310 (19%), Positives = 108/310 (34%), Gaps = 44/310 (14%) Query: 138 TIRNILGGTVFREPIICKNIPRLV-PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 196 +R L P IC P+LV KP + D + R + F Sbjct: 96 GLRKHLELFANFRPAIC--YPQLVDASPLKP---------ELVAGLDILIVRELNGDIYF 144 Query: 197 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILK 256 G + G M ++ + AH FQ A ++ L K+ +L+ Sbjct: 145 GQPRGVRAAPDGPFAGEREGFDT-MRYSEPEVRRIAHVAFQAAQKRAKKLLSVDKSNVLE 203 Query: 257 AYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDV 315 ++D+ ++ ++ + H +D+ Q+ K+ F V N GD+ Sbjct: 204 -TSQFWRDVMIDVSKEY-------ADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDI 255 Query: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375 SD + GS+G++ S + + K + E +HG+ + NP+A+I + Sbjct: 256 LSDEASMLTGSIGMLPSASLDKNNKGL-YEPSHGSAPDIAGKGI------ANPLATILSA 308 Query: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTT 435 L + + A +E+ +E G T D+A + T Sbjct: 309 AMLLRYSL------NRAEQADRIERAVKTVLEQGYRTGDIA---------TPGCRQVGTA 353 Query: 436 DFLDTIKSNL 445 D + + L Sbjct: 354 AMGDAVVAAL 363 >5J32-A nrPDB Length = 403 Score = 179 bits (455), Expect = 1e-45, Method: Composition-based stats. Identities = 59/350 (16%), Positives = 120/350 (34%), Gaps = 48/350 (13%) Query: 109 VAVKCATITPDEARVEEFKLKKM-----WKSPNGTIRNILGGTVFREPIIC---KNIPRL 160 V V T A+ + L W + +R G R + + Sbjct: 89 VGVPLPEETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATV 148 Query: 161 VPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMG 220 +P T+ R + D + R T + F + G+K E N G Sbjct: 149 LPQLVDASTLKRE----VAEGVDLMVVRELTGGIYF--GEPRGIKTNE--NGEEVGFNTE 200 Query: 221 MYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDK 280 +Y E I A F+ A +++ L K +L+A ++ + ++ Sbjct: 201 VYAAHE-IDRIARVAFETARKRRGKLCSVDKANVLEAS-ILWRKRVTALASEY------- 251 Query: 281 NKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDG 339 + H +D+ Q+++ F N GD+ SD + GS+G++ S + G Sbjct: 252 PDVELSHMYVDNAAMQLVRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLSDSG 311 Query: 340 KTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLE 399 + E HG+ + + NP+A+I + L++ + + A+ +E Sbjct: 312 PGL-FEPIHGSAPDIAGQDK------ANPLATILSAAMLLKYGLGEE------KAAKRIE 358 Query: 400 KVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRAL 449 + + +G T D+ + + + + ++D + Sbjct: 359 DAVLVALNNGFRTGDI---------YSAGTKLVGCKEMGEEVLKSVDSQV 399 >3TY3-A nrPDB Length = 366 Score = 176 bits (447), Expect = 1e-44, Method: Composition-based stats. Identities = 71/384 (18%), Positives = 131/384 (34%), Gaps = 63/384 (16%) Query: 67 KEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQ-KYSVAVKCATITPDEARVEE 125 K KL +D+ D G ++T + + + + + A+ A +P Sbjct: 39 KHKLKFDFIDL-----DAGWGTFERTGKALPERTVERLKTECNAALFGAVQSPTHKVA-- 91 Query: 126 FKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFV 185 + SP +R +G P+ + G + I R Y + + Sbjct: 92 -----GYSSPIVALRKKMGLYANVRPVKSLD---GAKGKPVDLVIVRENTECLYVKEERM 143 Query: 186 A---DRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK 242 + + + + K G + + + + I Y+I K Sbjct: 144 VQNTPGKRVAEAIRRISEEASTKI--------GKMAFEIAKSRQKI----RESGTYSIHK 191 Query: 243 KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSG 302 K + + K+ ++ DG F++ + D I + +++D MV ++ + Sbjct: 192 KPLVTIIHKSNVMSVTDGLFRESCRHA----QSLDPSYASINVDEQIVDSMVYRLFREPE 247 Query: 303 GF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKG 361 F V N GD+ SD A GSLGL+ S V + + +E HG+ Sbjct: 248 CFDVVVAPNLYGDILSDGAASLIGSLGLVPSANVGDN--FVMSEPVHGSAPDIAGRGI-- 303 Query: 362 RPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHG 421 NP+A+ + LE G D D+ ++KV E +T DL G Sbjct: 304 ----ANPVATFRSVALMLEFMGHQDAAADIY---TAVDKVL---TEGKVLTPDLGG---- 349 Query: 422 LSNVKLNEHFLNTTDFLDTIKSNL 445 T + D + +N+ Sbjct: 350 ---------KSGTNEITDAVLANI 364 >3BLV-B nrPDB Length = 354 Score = 174 bits (440), Expect = 8e-44, Method: Composition-based stats. Identities = 73/355 (20%), Positives = 123/355 (34%), Gaps = 82/355 (23%) Query: 100 SALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPR 159 + + K VA+K TP + K +S N T+R G P K+I Sbjct: 73 AVQSITKNLVALKGPLATP---------IGKGHRSLNLTLRKTFGLFANVRP--AKSIEG 121 Query: 160 LVPGWTK-PITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218 + + + R +Y + + GV Sbjct: 122 FKTTYENVDLVLIRENTEGEYSGIEHIV---------------------------CPGVV 154 Query: 219 MGMYN-TDESISGFAHSCFQYAIQ-KKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKT 276 + T ++ F+YA + + + K+TI + DG F ++ +E+ ++ Sbjct: 155 QSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY--- 211 Query: 277 DFDKNKIWYEHRLIDDMVAQVLKSSGGF---VWACKNYDGDVQSDILAQGF-GSLGLMTS 332 + E LID+ V +V+ + + V C N GD+ SD+ + GSLGL S Sbjct: 212 ----PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPS 267 Query: 333 VLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLI 392 + K EA HG+ + + NP A + + L H G L Sbjct: 268 ANIGH--KISIFEAVHGSAPDIAGQDK------ANPTALLLSSVMMLNHMG-------LT 312 Query: 393 RFAQMLEKVCVETVESG--AMTKDLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445 A ++ + T+ SG T DLAG T+ F + + L Sbjct: 313 NHADQIQNAVLSTIASGPENRTGDLAG-------------TATTSSFTEAVIKRL 354 >3ASJ-A nrPDB Length = 334 Score = 165 bits (418), Expect = 3e-41, Method: Composition-based stats. Identities = 56/310 (18%), Positives = 99/310 (31%), Gaps = 66/310 (21%) Query: 139 IRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTP 198 +R L P + +P PG D V R T + Sbjct: 87 LRRRLDLYANVRPAKSRPVPGSRPG------------------VDLVIVRENTEGLYVE- 127 Query: 199 KDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKA 257 +E + + + ++ + + A + + L+++ K +L Sbjct: 128 ------QERRYLDVAIADAVI----SKKASERIGRAALRIAEGRPRKTLHIAHKANVLPL 177 Query: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQ 316 G F D +E+ D + + ++D+ Q++ F V N GD+ Sbjct: 178 TQGLFLDTVKEVAK-------DFPLVNVQDIIVDNCAMQLVMRPERFDVIVTTNLLGDIL 230 Query: 317 SDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWT 376 SD+ A G LGL S + E HG+ + NP A+I + Sbjct: 231 SDLAAGLVGGLGLAPSGNIGDTTAV--FEPVHGSAPDIAGKGI------ANPTAAILSAA 282 Query: 377 RGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTD 436 L++ G+ + A+ +EK +E G T DL G T Sbjct: 283 MMLDYLGEKEA-------AKRVEKAVDLVLERGPRTPDLGGD-------------ATTEA 322 Query: 437 FLDTIKSNLD 446 F + + L Sbjct: 323 FTEAVVEALK 332 >1WPW-A nrPDB Length = 336 Score = 161 bits (406), Expect = 7e-40, Method: Composition-based stats. Identities = 59/311 (18%), Positives = 105/311 (33%), Gaps = 61/311 (19%) Query: 139 IRNILGGTVFREPIICKNIPRL-VPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFT 197 +R I P K+IP + I I R D YK + + Sbjct: 84 LRQIYDMYANIRP--AKSIPGIDTKYGNVDILIVRENTEDLYKGFEHIV----------- 130 Query: 198 PKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKA 257 DG V + F + A +A++++ + K +++ Sbjct: 131 -SDGVAVGMKIITRFAS--------------ERIAKVGLNFALRRRKKVTCVHKANVMRI 175 Query: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQ 316 DG F + + + K+ Y +D A ++++ F V +N GD+ Sbjct: 176 TDGLFAEACRSVLK---------GKVEYSEMYVDAAAANLVRNPQMFDVIVTENVYGDIL 226 Query: 317 SDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWT 376 SD +Q GSLG+ S + K E HG ++ NP A + + + Sbjct: 227 SDEASQIAGSLGIAPSANIGD--KKALFEPVHGAAFDIAGKNIG------NPTAFLLSVS 278 Query: 377 RGLEHRGKLDGNQDLIRFAQMLEKVCVETVES-GAMTKDLAGCIHGLSNVKLNEHFLNTT 435 E +L + I+ ++ LE + A+T D+ G T Sbjct: 279 MMYERMYELSNDDRYIKASRALENAIYLVYKERKALTPDVGGN-------------ATTD 325 Query: 436 DFLDTIKSNLD 446 D ++ I + L Sbjct: 326 DLINEIYNKLG 336 >1XAD-A nrPDB Length = 345 Score = 160 bits (405), Expect = 1e-39, Method: Composition-based stats. Identities = 57/309 (18%), Positives = 101/309 (32%), Gaps = 57/309 (18%) Query: 138 TIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFT 197 +IR L P+ K DFV R T + F Sbjct: 92 SIRKQLDLFANLRPVKVFESLSDASPLKKEYI----------DNVDFVIVRELTGGIYF- 140 Query: 198 PKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKA 257 + G+ E E +N + + A F+ A +++ + K +L+ Sbjct: 141 -GEPRGMSEAEAWNTE--------RYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEV 191 Query: 258 YDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQ 316 + ++ +E+ + + EH+ +D M +++S F V N GD+ Sbjct: 192 GE-FWRKTVEEVGRGY-------PDVALEHQYVDAMAMHLVRSPARFDVVVTGNIFGDIL 243 Query: 317 SDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWT 376 SD+ + GSLGL+ S + T E HG+ + NP A+I + Sbjct: 244 SDLASVLPGSLGLLPSASLGR--GTPVFEPVHGSAPDIAGKGI------ANPTAAILSAA 295 Query: 377 RGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTTD 436 LEH L + A+ +E + + + T Sbjct: 296 MMLEHAFGL------VELARKVEDAVAKALLE--------------TPPPDLGGSAGTEA 335 Query: 437 FLDTIKSNL 445 F T+ +L Sbjct: 336 FTATVLRHL 344 >4Y1P-A nrPDB Length = 337 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 67/393 (17%), Positives = 128/393 (32%), Gaps = 81/393 (20%) Query: 59 TRIIWQFIKEKLILP--HVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATI 116 ++ I + EK LP +++++ G +++ D + DS +K + +K Sbjct: 21 SKTILARLNEKFSLPIEYIEVEA-----GDTTKNKFGDALPKDSLRVIEKADMILKGPVG 75 Query: 117 TPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGW-TKPITIGRHAH 175 V +R + P K++P L + I + R Sbjct: 76 ETAADVV-------------VKLRLMYDLYANLRP--AKSLPGLENKFGDVDILVVRENT 120 Query: 176 GDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235 D YK + V T + T + + A Sbjct: 121 EDLYKGLEHVISDGVTVGIKVI--------------------------TRAASTRIAQVA 154 Query: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 295 A+++K + K+ +++ DG F + + + K+ Y +D A Sbjct: 155 LNQALRRKKKVVCVHKSNVMRITDGLFAESCRNVLK---------GKVEYSEMYVDAAAA 205 Query: 296 QVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354 ++++ F V +N GD+ SD Q GSLG+ S + + E HG Sbjct: 206 NLVRNPQAFDVIVTENTYGDILSDEAGQIAGSLGISPSANIGD--RKSLFEPVHGAAFDI 263 Query: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESG-AMTK 413 ++ NP A + + L+ +L G+ A+ L G +T Sbjct: 264 AGKNI------ANPTAFLLSVGMMLDRMQELSGDIRYNNAAKSLRDAIYSVYSEGKYLTP 317 Query: 414 DLAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLD 446 D+ G T + + I+S + Sbjct: 318 DVGGS-------------STTDEMISAIRSKIG 337 >3UDO-A nrPDB Length = 361 Score = 159 bits (403), Expect = 2e-39, Method: Composition-based stats. Identities = 65/269 (24%), Positives = 106/269 (39%), Gaps = 44/269 (16%) Query: 180 KATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYA 239 K D + R T + F +D + + Y+ T + I A F+ A Sbjct: 132 KGVDILCVRELTGGIYFGKQD---LGKESAYDTE--------IYTKKEIERIARIAFESA 180 Query: 240 IQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLK 299 +K +++ K +L + +++E+ K D I E+ +D+ Q++K Sbjct: 181 RIRKKKVHLIDKANVLASS-----ILWREVVANVAK---DYQDINLEYMYVDNAAMQIVK 232 Query: 300 SSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREH 358 + F V C N GD+ SD LA GSLGL++S + G + E A G+ + Sbjct: 233 NPSIFDVMLCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGL-YEPAGGSAPDIAHLN 291 Query: 359 QKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGC 418 NPIA I + L++ K + + AQ +E + G MTKDL Sbjct: 292 I------ANPIAQILSAALMLKYSFKEE------QAAQDIENAISLALAQGKMTKDLNA- 338 Query: 419 IHGLSNVKLNEHFLNTTDFLDTIKSNLDR 447 + +LNT + D I L Sbjct: 339 ----------KSYLNTDEMGDCILEILKE 357 >1IDM-A nrPDB Length = 343 Score = 159 bits (401), Expect = 3e-39, Method: Composition-based stats. Identities = 50/271 (18%), Positives = 95/271 (35%), Gaps = 47/271 (17%) Query: 176 GDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSC 235 + + D + R T + F + G+ E E +N + + A Sbjct: 118 EEIARGVDVLIVRELTGGIYF--GEPRGMSEAEAWNTE--------RYSKPEVERVARVA 167 Query: 236 FQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVA 295 F+ A +++ + K +L+ + ++ +E+ + + EH+ +D M Sbjct: 168 FEAARKRRKHVVSVDKANVLEVGE-FWRKTVEEVGRGY-------PDVALEHQYVDAMAM 219 Query: 296 QVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354 +++S F V N GD+ SD+ + GSLGL+ S + T E HG+ Sbjct: 220 HLVRSPARFDVVVTGNIFGDILSDLASVLPGSLGLLPSASLGR--GTPVFEPVHGSAPDI 277 Query: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414 + NP A+I + LEH L + A+ +E + + Sbjct: 278 AGKGI------ANPTAAILSAAMMLEHAFGL------VELARKVEDAVAKALLE------ 319 Query: 415 LAGCIHGLSNVKLNEHFLNTTDFLDTIKSNL 445 + T F T+ +L Sbjct: 320 --------TPPPDLGGSAGTEAFTATVLRHL 342 >5GRH-B nrPDB Length = 354 Score = 156 bits (395), Expect = 1e-38, Method: Composition-based stats. Identities = 61/329 (18%), Positives = 115/329 (34%), Gaps = 60/329 (18%) Query: 93 DDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPI 152 D++ ++ +A ++ VA+K T L KS N +R L I Sbjct: 57 DEEDIRNAIMAIRRNRVALKGNIET-------NHNLPPSHKSRNNILRTSLDLYANV--I 107 Query: 153 ICKNIPRLV-PGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYN 211 CK++P +V I I R +Y + + + + Sbjct: 108 HCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKII-------------- 153 Query: 212 FPAGGVGMGMYNTDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIF 270 T A F+ A + + + K I+K DG F +E+ Sbjct: 154 ------------TKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA 201 Query: 271 DKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGL 329 ++ +I +E+ ++D+ Q++ F V N G++ +++ A G GL Sbjct: 202 ARY-------PQITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGL 254 Query: 330 MTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQ 389 + E T TR+ + + NP A++ A L+H Sbjct: 255 VAGANYGHVYAVFE------TATRNTGKSIANKNI-ANPTATLLASCMMLDHL------- 300 Query: 390 DLIRFAQMLEKVCVETVESGAM-TKDLAG 417 L +A + K + ++++ M T D+ G Sbjct: 301 KLHSYATSIRKAVLASMDNENMHTPDIGG 329 >5HN5-A nrPDB Length = 353 Score = 153 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 66/351 (18%), Positives = 119/351 (33%), Gaps = 69/351 (19%) Query: 77 IQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPN 136 ++ +Y++ G+ + + + ++ + AT TP F L ++S Sbjct: 31 VRFEYYEGGVDVFQECGSPIREEDLEEIRRSDAVLFGATTTP-------FDLPG-YRSLI 82 Query: 137 GTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 196 T+R LG + IP L G + I I R Y V Sbjct: 83 LTLRKELGLYAN-----LRIIPDLRTG--REIVIVRENSEGLYFGIGAVV---------- 125 Query: 197 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILK 256 +G V + T E A + A + + K +L Sbjct: 126 ---NGRAVDVRLI--------------TREGAERIARFAVEQAKARGSFITFVHKANVL- 167 Query: 257 AYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDV 315 D F+ I +E+ + + +ID +++++ V +N GD+ Sbjct: 168 TGDKFFRRIVREVAGEE--------GVEVRDAIIDSFTIKLVRNPWEHGVILSENLFGDI 219 Query: 316 QSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAW 375 SD+ GS+G++ S DG + E HG+ + NPI +I + Sbjct: 220 LSDLATVHAGSIGIVPSGNYG-DGIAL-FEPVHGSAPDIAGKGI------ANPIGAILSG 271 Query: 376 TRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLAGCIHGLSNVK 426 L++ G LDG ++ V +G +T D+ G V+ Sbjct: 272 AMLLDYLG-LDG--------SLIRAAVRGYVVNGELTPDMGGRARTEDVVR 313 >2G4O-A nrPDB Length = 337 Score = 139 bits (350), Expect = 3e-33, Method: Composition-based stats. Identities = 49/268 (18%), Positives = 85/268 (31%), Gaps = 40/268 (14%) Query: 155 KNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPA 214 RL PG P+ G+ DFV R GT +G P Sbjct: 97 LRPARLYPGVASPL------SGN--PGIDFVVVREGTEGPY------TGNGGAIRVGTPN 142 Query: 215 GGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHY 274 NT + F+ A +++ L + K +L G + E+ + + Sbjct: 143 EVATEVSVNTAFGVRRVVADAFERARRRRKHLTLVHKTNVLTFAGGLWLRTVDEVGECY- 201 Query: 275 KTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSV 333 + ++ +D ++ G F V N GD+ +D+ A G +GL S Sbjct: 202 ------PDVEVAYQHVDAATIHMITDPGRFDVIVTDNLFGDIITDLAAAVCGGIGLAASG 255 Query: 334 LVCPDGKT-IEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLI 392 + E HG+ + +P A+I + L H G+ D Sbjct: 256 NIDATRANPSMFEPVHGSAPDIAGQGI------ADPTAAIMSVALLLSHLGEHDA----- 304 Query: 393 RFAQMLEKVCVETVE----SGAMTKDLA 416 A +++ + T D+ Sbjct: 305 --AARVDRAVEAHLATRGSERLATSDVG 330 >3FMX-X nrPDB Length = 364 Score = 132 bits (331), Expect = 3e-31, Method: Composition-based stats. Identities = 65/324 (20%), Positives = 111/324 (34%), Gaps = 41/324 (12%) Query: 99 DSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIP 158 D A ++Y A PD+ + K R V P+ Sbjct: 62 DWAEQLKQYDAIYFGAVGWPDKVPDHISLWGSLLK-----FRREFDQYVNIRPV------ 110 Query: 159 RLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVG 218 RL PG P + GD DFV R T + S + N V Sbjct: 111 RLFPGV--PCALANRKVGD----IDFVVVRENTEG------EYSSLGGIMFENTENEIVI 158 Query: 219 MGMYNTDESISGFAHSCFQYAIQK-KWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTD 277 T + F A ++ + + +TK+ + + D E HY Sbjct: 159 QESIFTRRGVDRILKYAFDLAEKRERKHVTSATKSNGMAISMPYW-DKRTEAMAAHY--- 214 Query: 278 FDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACKNYDGDVQSDILAQGFGSLGLMTSVLVC 336 + ++ + ID + A+ + F V N GD+ SD+ G++G+ S + Sbjct: 215 ---PHVSWDKQHIDILCARFVLQPERFDVVVASNLFGDILSDLGPACAGTIGIAPSANLN 271 Query: 337 PD-GKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFA 395 P+ E HG+ + ++ NPIA I++ LE G+ G++ R Sbjct: 272 PERNFPSLFEPVHGSAPDIFGKNI------ANPIAMIWSGALMLEFLGQ--GDERYQRAH 323 Query: 396 QMLEKVCVETVESGAMTKDLAGCI 419 + + G++T D+ G + Sbjct: 324 DDMLNAIERVIADGSVTPDMGGTL 347 >2B0T-A nrPDB Length = 738 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 38/112 (33%), Gaps = 1/112 (0%) Query: 298 LKSSGGFVWACKNYDGDVQSDILAQG-FGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYR 356 ++ + N D +D+ G+ M SV+ G + A G+ +H + Sbjct: 528 IRRGEDTISVTGNVLRDYNTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQ 587 Query: 357 EHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVES 408 + Q+ + + A H +GN A L+K + + Sbjct: 588 QVQEENHLRWDSLGEFLALAESFRHELNNNGNTKAGVLADALDKATEKLLNE 639 >1J1W-A nrPDB Length = 741 Score = 44.4 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 36/245 (14%), Positives = 70/245 (28%), Gaps = 24/245 (9%) Query: 173 HAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFA 232 +G K AD V D SG E + AG + D I + Sbjct: 418 EEYGSHDKTFQIPADG------VVRVTDESGKLLLE-QSVEAGDIWRMCQAKDAPIQDWV 470 Query: 233 HSCFQYAIQKKWPLYM------STKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYE 286 A P + ++ + KD D + + + Sbjct: 471 KLAVNRARATNTPAVFWLDPARAHDAQVIAKVERYLKDYDTSGLDIRILSPVEATRFSLA 530 Query: 287 HRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILA-QGFGSLGLMTSVLVCPDGKTIEAE 345 ++ + N D +D+ G+ M S++ G + Sbjct: 531 R----------IREGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMSGGGLFET 580 Query: 346 AAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVET 405 A G+ +H ++ + + + A LEH G N + A L++ + Sbjct: 581 GAGGSAPKHVQQFLEEGYLRWDSLGEFLALAASLEHLGNAYKNPKALVLASTLDQATGKI 640 Query: 406 VESGA 410 +++ Sbjct: 641 LDNNK 645 Score = 35.5 bits (80), Expect = 0.043, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 64/182 (35%), Gaps = 12/182 (6%) Query: 103 ATQKYSV-AVKCATITPDEARVEEFKLKKMWKSPNGTIRNIL---GGTVFREPIICKNIP 158 A ++ K + E +K + G+ N + G + R P+ KN Sbjct: 96 AIKELQQQGYKLPDYPEEPKTDTEKDVKARYDKIKGSAVNPVLREGNSDRRAPLSVKNYA 155 Query: 159 RLVPG----WT--KPITIGRHAHGDQYKATDF-VADRAGTFKMVFTPKDGSGVKEWEVYN 211 R P W+ + +GD Y + + G+ K+ KDGS + Sbjct: 156 RKHPHKMGAWSADSKSHVAHMDNGDFYGSEKAALIGAPGSVKIELIAKDGSSTVLKAKTS 215 Query: 212 FPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDG-RFKDIFQEIF 270 AG + + ++ F + + A ++ L + K T++K D F I E + Sbjct: 216 VQAGEIIDSSVMSKNALRNFIAAEIEDAKKQGVLLSVHLKATMMKVSDPIMFGQIVSEFY 275 Query: 271 DK 272 Sbjct: 276 KD 277 >6G3U-A nrPDB Length = 737 Score = 41.7 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 37/235 (15%), Positives = 76/235 (32%), Gaps = 8/235 (3%) Query: 177 DQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCF 236 ++Y + D + M DGS + + +V G + D I + Sbjct: 414 EEYGSHDKTFEMTADGTMRVVLADGSVLMQHKV---ETGDIWRACQTKDAPIRDWVKLAV 470 Query: 237 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 296 A Q P +A+D + + H T D + + Y + + + Sbjct: 471 TRARQSDTPAIFWLDPE--RAHDRELRKKVELYLKDHDLTGLDISIMGYNEAI--RVSME 526 Query: 297 VLKSSGGFVWACKNYDGDVQSDILA-QGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHY 355 L + N D +D+ G+ M S++ G + A G+ +H Sbjct: 527 RLIRGKDTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHV 586 Query: 356 REHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGA 410 ++ + + + A LE G GN + L++ + +++ Sbjct: 587 QQLVEENYLRWDSLGEFLALAVSLEETGIKTGNAKAKLLGKALDEATGKLLDNNK 641 >5Z16-A nrPDB Length = 751 Score = 41.7 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 41/114 (35%), Gaps = 5/114 (4%) Query: 307 ACKNYDGDVQSDILA-QGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTS 365 N D +D+ G+ M S++ G + A G+ +H ++ + Sbjct: 550 VTGNILRDYLTDLFPIMELGTSAKMLSIVPLMAGGGMYETGAGGSAPKHVQQLVEENHLR 609 Query: 366 TNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGA----MTKDL 415 + + A LE G + N A+ L++ + +++ T +L Sbjct: 610 WDSLGEFLALAVSLEEMGIKENNARTKLLAKTLDEATGKLLDNDKSPSRRTGEL 663 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 36/183 (19%), Positives = 59/183 (32%), Gaps = 16/183 (8%) Query: 119 DEARVEEFKLKKMW-KSPNGTIRNIL--GGTVFREPIICKNIPRLVPG----WT--KPIT 169 + A EE +K + K + +L G + R P KN + P W Sbjct: 121 NPATEEEKTIKARYGKCLGSAVNPVLREGNSDRRAPAAVKNYAKKHPHSMSEWKQWSQTH 180 Query: 170 IGRHAHGDQYKATD-FVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESI 228 + GD Y DR KM G + G + M+ + +++ Sbjct: 181 VSHMEEGDFYHGEKSMTLDRPRNVKMELITNSGKSIVLKPKVALQEGEIIDSMFMSKKAL 240 Query: 229 SGFAHSCFQYAIQKKWPLYMSTKNTILKAYD-----GRFKDIFQEIFDKHYKTDFDKNKI 283 F + + K T++K K ++E F+KH K FD+ I Sbjct: 241 CDFYEKQLDDCREAGILFSLHVKATMMKVSHPIVFGHCVKIYYKEAFEKHGKL-FDELGI 299 Query: 284 WYE 286 Sbjct: 300 NVN 302 >4ZDA-A nrPDB Length = 767 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 41/116 (35%), Gaps = 5/116 (4%) Query: 305 VWACKNYDGDVQSDILAQG-FGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRP 363 + A N D +D+ G+ M S++ G + A G+ +H + + Sbjct: 542 IAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEENH 601 Query: 364 TSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGA----MTKDL 415 + + A LE G GN+ A+ L+ + +E T +L Sbjct: 602 LRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGEL 657 Score = 36.7 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 67/186 (36%), Gaps = 13/186 (6%) Query: 117 TPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPG----WTKP--ITI 170 T DE ++++ K + + N +R G + R P K R P W++ + Sbjct: 118 TDDEKKIKDRYAKILGSAVNPVLRE--GNSDRRAPKAVKEYARKHPHSMGEWSQASRTHV 175 Query: 171 GRHAHGDQYKATD-FVADRAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESIS 229 GD Y DR KMV K G + AG + MY + +++ Sbjct: 176 ATMKTGDFYHGEKSMTLDRDRRVKMVLKTKSGEEIVLKPEVKLDAGDIIDSMYMSKKALI 235 Query: 230 GFAHSCFQYAIQKKWPLYMSTKNTILKAYD----GRFKDIFQEIFDKHYKTDFDKNKIWY 285 F + A + + K T++K G +F + ++ FD+ + Sbjct: 236 AFYEEQIEDAYKTGVMFSLHVKATMMKVSHPIVFGHAVKVFYKDAFAKHEKLFDELGVNV 295 Query: 286 EHRLID 291 + L D Sbjct: 296 NNGLSD 301 >5KVU-A nrPDB Length = 745 Score = 36.3 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 39/105 (37%), Gaps = 1/105 (0%) Query: 305 VWACKNYDGDVQSDILAQG-FGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRP 363 + A N D +D+ G+ M SV+ G + A G+ +H ++ + Sbjct: 542 IAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPKHVKQLVEENH 601 Query: 364 TSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVES 408 + + A G E G GN+ + L+ + +++ Sbjct: 602 LRWDSLGEFLALGAGFEDIGIKTGNERAKLLGKTLDAAIGKLLDN 646 Score = 35.9 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 42/205 (20%), Positives = 67/205 (32%), Gaps = 17/205 (8%) Query: 98 IDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNI 157 D A Y K T E ++E + + + N +R G + R P K Sbjct: 103 QDKGYAVPDYPADPK----TDQEKAIKERYARCLGSAVNPVLRQ--GNSDRRAPKAVKEY 156 Query: 158 PRLVPG----WT--KPITIGRHAHGDQYKATD-FVADRAGTFKMVFTPKDGSGVKEWEVY 210 R P W+ + HGD Y DRA +M K G + Sbjct: 157 ARKHPHSMGEWSMASRTHVAHMRHGDFYAGEKSMTLDRARNVRMELLAKSGKTIVLKPEV 216 Query: 211 NFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYD----GRFKDIF 266 G V M+ + +++ F Q A + + K T++K G IF Sbjct: 217 PLDDGDVIDSMFMSKKALCDFYEEQMQDAFETGVMFSLHVKATMMKVSHPIVFGHAVRIF 276 Query: 267 QEIFDKHYKTDFDKNKIWYEHRLID 291 + ++ FD + + L D Sbjct: 277 YKDAFAKHQELFDDLGVNVNNGLSD 301 >6IGZ-0 nrPDB Length = 245 Score = 30.1 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 12/24 (50%), Positives = 15/24 (62%), Gaps = 1/24 (4%) Query: 6 RVVRSLCRASGSRPAWAPAALTAP 29 R VR++ R + RP W P A TAP Sbjct: 21 RAVRNVTRMAAERPMWYPGA-TAP 43 >1XDT-T nrPDB Length = 535 Score = 29.0 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 24/115 (20%), Positives = 36/115 (31%), Gaps = 13/115 (11%) Query: 298 LKSSGGFVWACKNYDGDVQSDILAQGFGSL----------GLMTSVLVCPDGKTIEAEAA 347 ++ S G +C N D DV D SL + V + E Sbjct: 191 VRRSVGSSLSCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEF 250 Query: 348 HGTVTRHYREHQKGRPTSTNPI---ASIFAWTRGLEHRGKLDGNQDLIRFAQMLE 399 H T H + T TNP+ A+ AW + + +L + L Sbjct: 251 HQTALEHPELSELKTVTGTNPVFAGANYAAWAVNVAQVIDSETADNLEKTTAALS 305 >3AI7-A nrPDB Length = 831 Score = 28.2 bits (61), Expect = 6.9, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 31/92 (33%), Gaps = 12/92 (13%) Query: 166 KPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSG------VKEWEVYNFPAGGVGM 219 KP+ H++ + + F + ++GS V+ + + + Sbjct: 703 KPVLFAYHSYAHDVRGLIYDRPNHDNFNVHGYEEEGSTTTPYDMVRVNRIDRYELTAEAL 762 Query: 220 GMYNTDE------SISGFAHSCFQYAIQKKWP 245 M + D+ + F FQ+A+ + Sbjct: 763 RMIDADKYADKIDELEKFRDEAFQFAVDNGYD 794 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.125 0.323 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,488,953 Number of Sequences: 36641 Number of extensions: 670504 Number of successful extensions: 1986 Number of sequences better than 10.0: 54 Number of HSP's better than 10.0 without gapping: 62 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1673 Number of HSP's gapped (non-prelim): 101 length of query: 452 length of database: 10,336,785 effective HSP length: 100 effective length of query: 352 effective length of database: 6,672,685 effective search space: 2348785120 effective search space used: 2348785120 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.8 bits)