BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P48728 (403 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1WSR-A nrPDB 775 0.0 3GIR-A nrPDB 255 2e-68 1YX2-A nrPDB 199 1e-51 1WOR-A nrPDB 188 5e-48 1V5V-A nrPDB 180 1e-45 3A8J-A nrPDB 165 4e-41 5L46-A nrPDB 95 5e-20 4P9S-A nrPDB 87 1e-17 1PJ5-A nrPDB 70 1e-12 2GAG-A nrPDB 68 6e-12 3TFJ-A nrPDB 65 4e-11 1VRQ-A nrPDB 63 2e-10 5X1I-A nrPDB 48 7e-06 4RVO-A nrPDB 35 0.055 3H1Q-A nrPDB 32 0.45 1H2B-A nrPDB 32 0.64 3W9B-A nrPDB 30 2.8 4WEM-A nrPDB 29 3.5 4WEN-A nrPDB 29 3.7 4YKF-A nrPDB 29 3.8 1FL2-A nrPDB 28 7.0 >1WSR-A nrPDB Length = 375 Score = 775 bits (2000), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 29 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK 88 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK Sbjct: 1 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK 60 Query: 89 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC 148 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC Sbjct: 61 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC 120 Query: 149 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA 208 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA Sbjct: 121 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA 180 Query: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA 268 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA Sbjct: 181 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA 240 Query: 269 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA 328 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA Sbjct: 241 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA 300 Query: 329 PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAV 388 PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAV Sbjct: 301 PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAV 360 Query: 389 VSKMPFVPTNYYTLK 403 VSKMPFVPTNYYTLK Sbjct: 361 VSKMPFVPTNYYTLK 375 >3GIR-A nrPDB Length = 393 Score = 255 bits (652), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 152/370 (41%), Positives = 204/370 (55%), Gaps = 13/370 (3%) Query: 33 LRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILGS 92 L+ PLY+ H G K AFAGW +P+ Y HLHTR H LFD+SHM + G Sbjct: 33 LKTLPLYELHEKAGAKFGAFAGWRMPLTYPLGVLKEHLHTRAHAGLFDISHMKLIAVEGP 92 Query: 93 DRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 V+ + + D A L+ Q S NE GILDDLI+T +E +V+NAG + D Sbjct: 93 KAVEFLSYALPVDAALLKIGQSRYSYLLNERAGILDDLILTRLAECRFMLVANAGNAQAD 152 Query: 153 LALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVL-QAGVADDLRKLPFMTSAVME 211 A ++ + + Q + L+ LLALQGP AA VL AG+ + +L FM + Sbjct: 153 FAELEKRAFGFECQ-----VIALERVLLALQGPQAAAVLADAGLPGN--ELLFMQGFEPQ 205 Query: 212 VFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLC 271 +TR GYTGEDG EI++P+ A LA +L + V+ GLAARDSLRLEAGLC Sbjct: 206 ----QDWFITRSGYTGEDGFEIALPIGCARALAEKLLGDSRVEWVGLAARDSLRLEAGLC 261 Query: 272 LYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEG-APM 330 L+GNDI TTP++ +L+W + K R F GAK + L+ R RVGL + P+ Sbjct: 262 LHGNDITPDTTPIDAALTWAVPKNVREKAQFYGAKAFLESLQKGPSRCRVGLKPQTRQPI 321 Query: 331 RAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVS 390 RA + + + EG +IG VTSG PS VAMGYVP + GT + E+R K+ V Sbjct: 322 RAGAVLFDNEGNRIGVVTSGGFGPSFDGPVAMGYVPVAWKVEGTEVFTELRGKKIALSVH 381 Query: 391 KMPFVPTNYY 400 +PFV Y+ Sbjct: 382 SLPFVEQRYF 391 >1YX2-A nrPDB Length = 365 Score = 199 bits (507), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 130/374 (34%), Positives = 198/374 (52%), Gaps = 26/374 (6%) Query: 32 VLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILG 91 +L+RTPL+D + +GGK + F GW LPVQ+ S H R LFDVSHM + ++ G Sbjct: 4 MLKRTPLFDLYKEYGGKTIDFGGWELPVQFS-SIKKEHEAVRTAAGLFDVSHMGEVEVSG 62 Query: 92 SDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEK 151 +D + ++ L+ D++ L P + + GG +DDL++ E +V NA +K Sbjct: 63 NDSLSFLQRLMTNDVSALTPGRAQYTAMCYPDGGTVDDLLIYQKGENRYLLVINASNIDK 122 Query: 152 DLALMQDKVR---ELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKL-PFMTS 207 DLA M++ ++ NQ + ALLA+QGP A +L+ D+ L PF Sbjct: 123 DLAWMKEHAAGDVQIDNQSDQI-------ALLAVQGPKAEAILKNLTDADVSALKPF--- 172 Query: 208 AVMEVFGVSGCR--VTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVK---LAGLAARD 262 A ++ +SG + ++R GYTGEDG EI A+H+ I+ + GL ARD Sbjct: 173 AFIDEADISGRKALISRTGYTGEDGYEIYCRSDDAMHIWKKIIDAGDAYGLIPCGLGARD 232 Query: 263 SLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVG 322 +LR EA + LYG ++ TP+E + + + ++ + DF G V+ Q + +R+ VG Sbjct: 233 TLRFEANIPLYGQELTRDITPIEAGIGFAVKHKKES--DFFGKSVLSEQKENGAKRKLVG 290 Query: 323 L-MCE-GAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEV 380 L M E G P + N G +G VT+G SP+L KNV + + E S GT++ VE+ Sbjct: 291 LEMIEKGIPRHGYEVFQN--GKSVGKVTTGTQSPTLGKNVGLALIDSETSEIGTVVDVEI 348 Query: 381 RRKQQMAVVSKMPF 394 R+K A V K PF Sbjct: 349 RKKLVKAKVVKTPF 362 >1WOR-A nrPDB Length = 364 Score = 188 bits (477), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 124/369 (33%), Positives = 191/369 (51%), Gaps = 21/369 (5%) Query: 33 LRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILGS 92 ++RTPL++ H+ G KMV FAGW +P+ Y S + + R+ +FDVSHM + + G Sbjct: 1 MKRTPLFEKHVELGAKMVDFAGWEMPLYYT-SIFEEVMAVRKSVGMFDVSHMGEFLVKGP 59 Query: 93 DRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 + V ++ L+ D + L + S+ NE GGI+DDL+V S +V NA EKD Sbjct: 60 EAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALMVVNAANIEKD 119 Query: 153 LALMQDKVRELQNQGRDVGLEVLD----NALLALQGPTAAQVLQAGVADDLRKLPFMTSA 208 +++ ++ +EV + AL+A QGP A + LQ V D L ++ + + Sbjct: 120 FNW-------IKSHSKNFDVEVSNISDTTALIAFQGPKAQETLQELVEDGLEEIAYYSFR 172 Query: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATA---ILKNPEVKLAGLAARDSLR 265 V GV V+R GYTGEDG E+ + A + A +L+ + + AGL ARD R Sbjct: 173 KSIVAGVE-TLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKIDGRPAGLGARDVCR 231 Query: 266 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 325 LEA LYG D+DE+T P E LSW + + DF G + ++ + K +V+R+ V L Sbjct: 232 LEATYLLYGQDMDENTNPFEVGLSWVV----KLNKDFVGKEALL-KAKEKVERKLVALEL 286 Query: 326 EGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQ 385 G + + G ++G +TSG SP+L K++A+ V + +V K Sbjct: 287 SGKRIARKGYEVLKNGERVGEITSGNFSPTLGKSIALALVSKSVKIGDQLGVVFPGGKLV 346 Query: 386 MAVVSKMPF 394 A+V K PF Sbjct: 347 EALVVKKPF 355 >1V5V-A nrPDB Length = 401 Score = 180 bits (456), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 121/404 (29%), Positives = 200/404 (49%), Gaps = 41/404 (10%) Query: 31 EVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKIL 90 ++++R ++D+H H K+ FAGW +P+ Y S + HL R +FDVSHM + Sbjct: 3 QMVKRVHIFDWHKEHARKIEEFAGWEMPIWY-SSIKEEHLAVRNAVGIFDVSHMGEIVFR 61 Query: 91 GSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWE 150 G D +K ++ + DI++ GT +L NE G I D+ +V N ++ ++ +E Sbjct: 62 GKDALKFLQYVTTNDISKPPAISGTYTLVLNERGAIKDETLVFNMGNNEYLMICDSDAFE 121 Query: 151 KDLAL---MQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTS 207 K A ++ + + ++ L+ D A+ A+QGP A + + D+ ++ + + Sbjct: 122 KLYAWFTYLKRTIEQFTKLDLEIELKTYDIAMFAVQGPKARDLAKDLFGIDINEMWWFQA 181 Query: 208 AVMEVFGVSGCRVTRCGYTGEDGVEISVPVAG--------------AVHLATAIL---KN 250 +E+ G+ ++R GYTGE+G E+ + A A+H+ IL K Sbjct: 182 RWVELDGIK-MLLSRSGYTGENGFEVYIEDANPYHPDESKRGEPEKALHVWERILEEGKK 240 Query: 251 PEVKLAGLAARDSLRLEAGLCLYGN----------DIDEHTTPVEGSLSWTLGKRRRAAM 300 +K GL ARD+LRLEAG LYGN DIDE TP++ +L + + + Sbjct: 241 YGIKPCGLGARDTLRLEAGYTLYGNETKELQLLSTDIDE-VTPLQANLEFAIYWDK---- 295 Query: 301 DFPGAKVIVPQLKGRVQRRRV--GLMCEGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKK 358 DF G ++ Q + V R+ V ++ +G P + N G IG VTSG SP L Sbjct: 296 DFIGKDALLKQKERGVGRKLVHFKMIDKGIPREGYKVYAN--GEMIGEVTSGTLSPLLNV 353 Query: 359 NVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTNYYTL 402 + + +V EY++PG + VE+R +++ AV PF Y L Sbjct: 354 GIGIAFVKEEYAKPGIEIEVEIRGQRKKAVTVTPPFYDPKKYGL 397 >3A8J-A nrPDB Length = 364 Score = 165 bits (417), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 118/371 (31%), Positives = 189/371 (50%), Gaps = 25/371 (6%) Query: 34 RRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILGSD 93 ++TPLY+ H G +MV F GW +P+ Y S D H R +FDVSHM + GS Sbjct: 3 QQTPLYEQHTLCGARMVDFHGWMMPLHY-GSQIDEHHAVRTDAGMFDVSHMTIVDLRGSR 61 Query: 94 RVKLMESLVVGDIAEL-RPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 + + L+ D+A+L + + S N +GG++DDLIV +E +V N+ EKD Sbjct: 62 TREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKD 121 Query: 153 LALMQDKVRELQNQGRDVGLEVL---DNALLALQGPTAAQVLQAGVADDLRKLPFMTSAV 209 L+ + G+E+ D +++A+QGP A Q A + +D ++ + Sbjct: 122 LSW-------ITQHAEPFGIEITVRDDLSMIAVQGPNA-QAKAATLFNDAQRQA--VEGM 171 Query: 210 MEVFGVSG--CRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLE 267 FGV + GYTGE G EI++P A A+++ VK GL ARD+LRLE Sbjct: 172 KPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVE-AGVKPCGLGARDTLRLE 230 Query: 268 AGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEG 327 AG+ LYG ++DE +P+ ++ WT+ A DF G + + Q + ++ +M E Sbjct: 231 AGMNLYGQEMDETISPLAANMGWTIA-WEPADRDFIGREALEVQREHGTEKLVGLVMTEK 289 Query: 328 APMRAHSPI--LNMEGTK-IGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQ 384 +R P+ + +G + G +TSG SP+L ++A+ VP G +V++R ++ Sbjct: 290 GVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVP---EGIGETAIVQIRNRE 346 Query: 385 QMAVVSKMPFV 395 V+K FV Sbjct: 347 MPVKVTKPVFV 357 >5L46-A nrPDB Length = 841 Score = 95.1 bits (235), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 100/376 (26%), Positives = 167/376 (44%), Gaps = 44/376 (11%) Query: 53 AGWSLP---------VQYRDSHTDSHL---------HTRQHCSLFDVSHMLQTKILGSDR 94 AGW P QYR S ++ Q ++ D+S + I G D Sbjct: 461 AGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVAVTDLSPFGKFNIKGQDS 520 Query: 95 VKLMESLVVGDIAELRPNQG--TLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 ++L++ L A + P G +S G + +L V++ S G +++ +G D Sbjct: 521 IRLLDHL----FANVIPKVGFTNISHMLTPKGRVYAELTVSHQSPGEFLLITGSGSELHD 576 Query: 153 LALMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTSA 208 L +++ E G DV ++ + + L L + GP A +VLQ ++DL F+ + Sbjct: 577 LRWIEE---EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQKLTSEDLSDDVFKFLQTK 633 Query: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLR 265 ++V + R YTGE G E+ +V L AI+ + + G A ++LR Sbjct: 634 SLKVSNIP-VTAIRISYTGELGWELYHRREDSVALYDAIMNAGQEEGIDNFGTYAMNALR 692 Query: 266 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 325 LE +G +++ T P+E L + + + A DF G + + Q+K + +RR L+C Sbjct: 693 LEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPA--DFIGKQAL-KQIKAKGLKRR--LVC 747 Query: 326 EGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVR 381 P N G +G TSG S S++K++A YVP + S G + VE+ Sbjct: 748 LTLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAYVPVQLSEVGQQVEVELL 807 Query: 382 RKQQMAVVSKMPFVPT 397 K AV+ + P V T Sbjct: 808 GKNYPAVIIQEPLVLT 823 >4P9S-A nrPDB Length = 848 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 99/378 (26%), Positives = 164/378 (43%), Gaps = 46/378 (12%) Query: 53 AGWSLP---------VQYRDSHTDSHL---------HTRQHCSLFDVSHMLQTKILGSDR 94 AGW P QYR S ++ Q + D+S + I G D Sbjct: 462 AGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDS 521 Query: 95 VKLMESLVVGDIAELRPNQG--TLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 +L++ L A + P G +S G + +L V++ S G +++ +G D Sbjct: 522 TQLLDHLC----ANVIPKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHD 577 Query: 153 LALMQDK-VRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTS 207 L +++ VR G DV + + + L L + GP A +VLQ ++DL F+ + Sbjct: 578 LRWIEEAAVR----GGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQT 633 Query: 208 AVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAIL---KNPEVKLAGLAARDSL 264 +++ + R YTGE G E+ + L I+ + + G A ++L Sbjct: 634 KSLKISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNAL 692 Query: 265 RLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLM 324 RLE +G++++ T P+E L + + + A +F G K + Q+K + +RR L+ Sbjct: 693 RLEKAFRAWGSEMNCDTNPLEAGLDYFIKLNKPA--NFTG-KQALKQIKAKGLKRR--LV 747 Query: 325 CEGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEV 380 C P N +G IG TSG S S++K++A YVP E S G + VE+ Sbjct: 748 CLTLATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVEL 807 Query: 381 RRKQQMAVVSKMPFVPTN 398 K A + + P V T Sbjct: 808 LGKNYPATIIQEPLVLTE 825 >1PJ5-A nrPDB Length = 830 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 90/401 (22%), Positives = 155/401 (38%), Gaps = 49/401 (12%) Query: 33 LRRTPLYDFHLAHGGKMVAFAGWSLPVQY------------------RDSHTD------- 67 LR +P + H G + GW P + RD+ + Sbjct: 430 LRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPAEWLPPARDAWSGMFSSPIA 489 Query: 68 --SHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGG 125 TR +++D++ + + ++ G +KL++ L D+A+ +P T +L + AGG Sbjct: 490 AAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAK-KPGAVTYTLLLDHAGG 548 Query: 126 ILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVG-LEVLDNA----LL 180 + D+ V SE + +N D A + R G ++V D + Sbjct: 549 VRSDITVARLSEDTFQLGANGNI---DTAYFERAARHQTQSGSATDWVQVRDTTGGTCCI 605 Query: 181 ALQGPTAAQVLQAGVADDLRK--LPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVA 238 L GP A ++ DD L + + + + G+ R Y GE G E+ Sbjct: 606 GLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIP-VTAMRLSYVGELGWELYTSAD 664 Query: 239 GAVHLATAILKNPE---VKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKR 295 L A+ + + V AG AA SLRLE G +G D+ P E L + + Sbjct: 665 NGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAGLGFAV--- 721 Query: 296 RRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEG--APMRAHSPILNMEGTKIGTVTSGCPS 353 + A F G + + + RR L + + + P+ E +G VTS Sbjct: 722 KMAKESFIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKE-QAVGYVTSAAYG 780 Query: 354 PSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPF 394 ++ K +A Y+P S G + +E ++ A V++ P Sbjct: 781 YTVAKPIAYSYLPGTVSV-GDSVDIEYFGRRITATVTEDPL 820 >2GAG-A nrPDB Length = 965 Score = 68.2 bits (165), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 87/386 (22%), Positives = 152/386 (39%), Gaps = 36/386 (9%) Query: 34 RRTPLYDFHLAHGGKMVAFAGWSLPVQYRDS--HTDSHLH-----TRQHCSLFDVSHMLQ 86 R T ++ +HL+HG + W P Y + D ++ R + D + + + Sbjct: 575 RITAMHSWHLSHGAEFEDVGQWKRPWYYPQAGETMDQAVYRESKAVRDSVGMLDATTLGK 634 Query: 87 TKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNA 146 +I G D + + + +L+ G + G I DD + +E + + Sbjct: 635 IEIRGKDAAEFLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLLHTTT 694 Query: 147 GCWEKDLALMQDKVRELQNQGRDVGL---EVLDN-ALLALQGPTAAQVL-QAGVADDLRK 201 G L +++ LQ + D+ + V + A +A+ GP + V+ + D+ Sbjct: 695 GGAADVLDWLEEW---LQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKLASTVDVSN 751 Query: 202 LPFMTSAVMEVFGVSG--CRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLA 256 F A +V SG R++R ++GE EI+VP + + + E + Sbjct: 752 EGFKFMAFKDVVLDSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAGEEFNITPY 811 Query: 257 GLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRV 316 G LR E G + G D D TP + + W + K + DF G + R Sbjct: 812 GTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVVSKLK----DFIGNRSYSRADNARE 867 Query: 317 QRRRVGLMC---------EGAPMRAHSPILNMEGTK--IGTVTSGCPSPSLKKNVAMGYV 365 R+++ + EGA + A S L EG G VTS SP+L + + + Sbjct: 868 DRKQLVSVLPVDKSLRLPEGAALVA-SDALASEGITPMEGWVTSSYDSPNLGRTFGLALI 926 Query: 366 PCEYSRPGTMLLVEVRRKQQMAVVSK 391 +R G +L V + VVS+ Sbjct: 927 KNGRNRIGEVLKTPVGDQLVDVVVSE 952 >3TFJ-A nrPDB Length = 369 Score = 65.5 bits (158), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 64/343 (18%), Positives = 138/343 (40%), Gaps = 27/343 (7%) Query: 64 SHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEA 123 S DS+ H ++H ++DV+ Q +I G D +L++ + D+++ + + +E Sbjct: 43 SIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIIDEN 102 Query: 124 GGILDDLIVTNTSEGHLYVV---SNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDNA-- 178 G +++D +V E ++ S+ + K LA G +++++ Sbjct: 103 GNLVNDPVVLKLDENKWWISIADSDVIFFAKGLA-----------SGHKFDVKIVEPVVD 151 Query: 179 LLALQGPTAAQVLQAGVADDLRKLPFMTSAVMEVFGVSGCR--VTRCGYTGEDGVEISVP 236 ++A+QGP + +++ + +L F + F G + + R G++ + G E+ V Sbjct: 152 IMAIQGPKSFALMEKVFGKKITELKFFG---FDYFDFEGTKHLIARSGWSKQGGYEVYVE 208 Query: 237 -VAGAVHLATAILK-NPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGK 294 L + + E + R+E+ L YGND D + P E + Sbjct: 209 NTQSGQKLYDHLFEVGKEFNVGPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQYVS- 267 Query: 295 RRRAAMDFPGAKVIVPQLKGRVQR--RRVGLMCEGAPMRAHSPILNMEGTKIGTVTSGCP 352 + ++F G + + Q+ R V + + + I + IG + S C Sbjct: 268 -LDSDINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSACY 326 Query: 353 SPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFV 395 SP +K + + + + +++ V +PF+ Sbjct: 327 SPHFQKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369 >1VRQ-A nrPDB Length = 964 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 80/374 (21%), Positives = 143/374 (38%), Gaps = 42/374 (11%) Query: 34 RRTPLYDFHLAHGGKMVAFAGWSLPVQY-RDSHT-DSHLH-----TRQHCSLFDVSHMLQ 86 R T ++ +HLAHG K W P Y +D + D ++ R + D S + + Sbjct: 574 RLTAMHPWHLAHGAKFEDVGQWKRPWYYPQDGESMDEAVYRECKAVRDSVGMLDASTLGK 633 Query: 87 TKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNA 146 +I G D + + + +L+ G + G I DD + +E + + Sbjct: 634 IEIRGKDAAEFLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLMHTTT 693 Query: 147 GCWEKDLALMQDKVR----ELQNQGRDVGLEVLDNALLALQGPTAAQVL-QAGVADDLRK 201 G L +++ ++ EL V ++ A +A+ GP + V+ + + D+ Sbjct: 694 GGAADVLDWLEEWLQTEWPELDVTCTSVTEQL---ATVAVVGPRSRDVIAKLASSLDVSN 750 Query: 202 LPFMTSAVMEVFGVSG--CRVTRCGYTGEDGVEISVPVAGAVHLATAIL---KNPEVKLA 256 F A +V SG R++R ++GE EI++P + + + + + Sbjct: 751 DAFKFMAFQDVTLDSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAGQEFNITPY 810 Query: 257 GLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRV 316 G LR E G + G D D TP + + W + K + DF G + + R Sbjct: 811 GTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVVSKLK----DFVGKRSFSREDNVRE 866 Query: 317 QRRRV--------------GLMCEGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAM 362 R+ + G A A + ME G VT SP+L + + Sbjct: 867 DRKHLVSVLPVDSSLRLAEGAALVAADAVASEGVTPME----GWVTHAYNSPALGRTFGL 922 Query: 363 GYVPCEYSRPGTML 376 + +R G +L Sbjct: 923 ALIKNGRNRIGEVL 936 >5X1I-A nrPDB Length = 474 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 48/185 (25%), Positives = 72/185 (38%), Gaps = 9/185 (4%) Query: 73 RQHCSLFD-VSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLI 131 R LFD HM+ I G D +KL+ ++ PN+ + G ++ D I Sbjct: 52 RNSAVLFDQTHHMVDLYIRGKDALKLLSDTMINSPKGWEPNKAKQYVPVTPYGHVIGDGI 111 Query: 132 VTNTSEGHLYVVSNAGCWEKDLALMQ------DKVRELQNQGRDVGLEVLDNAL-LALQG 184 + +E V A + Q D V + ++ R +G V + +QG Sbjct: 112 IFYLAEEEFVYVGRAPAANWLMYHAQTGGYNVDIVHDDRSPSRPMGKPVQRISWRFQIQG 171 Query: 185 PTAAQVLQAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLA 244 P A V++ L KL F A M + G+ R R G G G+EI P Sbjct: 172 PKAWDVIEKLHGGTLEKLKFFNMAEMNIAGMK-IRTLRHGMAGAPGLEIWGPYETQEKAR 230 Query: 245 TAILK 249 AIL+ Sbjct: 231 NAILE 235 >4RVO-A nrPDB Length = 436 Score = 35.0 bits (79), Expect = 0.055, Method: Compositional matrix adjust. Identities = 42/174 (24%), Positives = 71/174 (40%), Gaps = 34/174 (19%) Query: 149 WEKDLALM-QDKVRELQNQGRDVGLEVLDNA-----LLALQGPTAAQVLQAGVADDLRKL 202 WE+++ +M ++K++ELQ Q + + N+ + + G T + DD+RK+ Sbjct: 7 WEEEIEIMSREKLQELQLQRLKKTINIAANSPYYKEVFSKNGITGDSIQSL---DDIRKI 63 Query: 203 PFMTSAVMEV---FGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLA 259 PF T + M FG+ + R DGV I H ++ NP V + Sbjct: 64 PFTTKSDMRANYPFGLVAGDMKR------DGVRI--------HSSSGTTGNPTVIVHSQH 109 Query: 260 ARDSLRLEAGLCLY-----GNDIDEHTTP---VEGSLSWTLGKRRRAAMDFPGA 305 DS CLY D+ ++++ G L + G R + P A Sbjct: 110 DLDSWANLVARCLYMVGIRKTDVFQNSSGYGMFTGGLGFQYGAERLGCLTVPAA 163 >3H1Q-A nrPDB Length = 272 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 23/41 (56%) Query: 278 DEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQR 318 D+ PV G+L W + +D+ GA IV +LK +V+R Sbjct: 46 DQEGIPVAGALKWASVVKDGLVVDYIGAIQIVRELKAKVER 86 >1H2B-A nrPDB Length = 359 Score = 31.6 bits (70), Expect = 0.64, Method: Compositional matrix adjust. Identities = 36/122 (29%), Positives = 54/122 (44%), Gaps = 13/122 (10%) Query: 235 VPVAGAVHLATAILK--NPEVKLAGLAARDSLRLEAGLCLYGND--IDEHTTPVEGSLSW 290 V V G H+A +LK P +A + L+L L G D +D PV+ + Sbjct: 193 VGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERL---GADHVVDARRDPVKQVMEL 249 Query: 291 TLGKRRRAAMDFPGAKVIV---PQLKGRVQRRRV---GLMCEGAPMRAHSPILNMEGTKI 344 T G+ AMDF G++ V P L GR+ R + G +R S ++ EG+ + Sbjct: 250 TRGRGVNVAMDFVGSQATVDYTPYLLGRMGRLIIVGYGGELRFPTIRVISSEVSFEGSLV 309 Query: 345 GT 346 G Sbjct: 310 GN 311 >3W9B-A nrPDB Length = 328 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 2/56 (3%) Query: 322 GLMCEGA-PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTML 376 GL C+GA P PIL + GT T S + + +GY PC S P ML Sbjct: 26 GLTCQGASPSSVSKPILLVPGTGT-TGPQSFDSNWIPLSTQLGYTPCWISPPPFML 80 >4WEM-A nrPDB Length = 272 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 11/77 (14%) Query: 271 CLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPM 330 L G + TPV G + G A D+ GA V++ G ++ GL PM Sbjct: 52 ILLGRTKEAFATPVTGGVD---GIPHIAFTDYEGASVVLRNPDGETNKK--GLAYFVLPM 106 Query: 331 RAHSPILNMEGTKIGTV 347 + N EGTK+G+V Sbjct: 107 K------NAEGTKVGSV 117 >4WEN-A nrPDB Length = 275 Score = 28.9 bits (63), Expect = 3.7, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 11/77 (14%) Query: 271 CLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPM 330 L G + TPV G + G A D+ GA V++ G ++ GL PM Sbjct: 52 ILLGRTKEAFATPVTGGVD---GIPHIAFTDYEGASVVLRNPDGETNKK--GLAYFVLPM 106 Query: 331 RAHSPILNMEGTKIGTV 347 + N EGTK+G+V Sbjct: 107 K------NAEGTKVGSV 117 >4YKF-A nrPDB Length = 521 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 22/121 (18%) Query: 217 GCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLCLYGND 276 G RV G G GVE ++ +AG V T + PE+K A +D LR L D Sbjct: 355 GKRVAVIG-GGNSGVEAAIDLAGIVEHVTLLEFAPEMK-ADQVLQDKLR-----SLKNVD 407 Query: 277 I--DEHTTPVEGSLSWTLG--KRRRAAMDFPGAKV--------IVPQ---LKGRVQRRRV 321 I + TT V+G S +G R R + D ++ ++P L+G V+R R+ Sbjct: 408 IILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVERNRM 467 Query: 322 G 322 G Sbjct: 468 G 468 >1FL2-A nrPDB Length = 310 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 38/121 (31%), Positives = 55/121 (45%), Gaps = 22/121 (18%) Query: 217 GCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLCLYGND 276 G RV G G GVE ++ +AG V T + PE+K A +D LR L D Sbjct: 144 GKRVAVIG-GGNSGVEAAIDLAGIVEHVTLLEFAPEMK-ADQVLQDKLR-----SLKNVD 196 Query: 277 I--DEHTTPVEGSLSWTLG--KRRRAAMDFPGAKV--------IVPQ---LKGRVQRRRV 321 I + TT V+G S +G R R + D ++ ++P L+G V+R R+ Sbjct: 197 IILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVERNRM 256 Query: 322 G 322 G Sbjct: 257 G 257 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1WSR-A nrPDB 478 e-135 1V5V-A nrPDB 402 e-112 3GIR-A nrPDB 394 e-110 1WOR-A nrPDB 393 e-110 1YX2-A nrPDB 389 e-108 3A8J-A nrPDB 360 e-100 2GAG-A nrPDB 355 1e-98 1VRQ-A nrPDB 354 3e-98 5L46-A nrPDB 335 3e-92 1PJ5-A nrPDB 333 5e-92 4P9S-A nrPDB 332 2e-91 3TFJ-A nrPDB 293 9e-80 5X1I-A nrPDB 193 1e-49 Sequences not found previously or not previously below threshold: 1NRK-A nrPDB 45 6e-05 6QE4-A nrPDB 33 0.19 1YPF-A nrPDB 31 0.80 3H1Q-A nrPDB 30 1.9 3F9U-A nrPDB 29 3.1 >1WSR-A nrPDB Length = 375 Score = 478 bits (1231), Expect = e-135, Method: Composition-based stats. Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 29 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK 88 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK Sbjct: 1 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK 60 Query: 89 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC 148 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC Sbjct: 61 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC 120 Query: 149 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA 208 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA Sbjct: 121 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA 180 Query: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA 268 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA Sbjct: 181 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA 240 Query: 269 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA 328 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA Sbjct: 241 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA 300 Query: 329 PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAV 388 PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAV Sbjct: 301 PMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAV 360 Query: 389 VSKMPFVPTNYYTLK 403 VSKMPFVPTNYYTLK Sbjct: 361 VSKMPFVPTNYYTLK 375 >1V5V-A nrPDB Length = 401 Score = 402 bits (1034), Expect = e-112, Method: Composition-based stats. Identities = 117/403 (29%), Positives = 198/403 (49%), Gaps = 39/403 (9%) Query: 31 EVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKIL 90 ++++R ++D+H H K+ FAGW +P+ Y S + HL R +FDVSHM + Sbjct: 3 QMVKRVHIFDWHKEHARKIEEFAGWEMPIWYS-SIKEEHLAVRNAVGIFDVSHMGEIVFR 61 Query: 91 GSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWE 150 G D +K ++ + DI++ GT +L NE G I D+ +V N ++ ++ +E Sbjct: 62 GKDALKFLQYVTTNDISKPPAISGTYTLVLNERGAIKDETLVFNMGNNEYLMICDSDAFE 121 Query: 151 KDLAL---MQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTS 207 K A ++ + + ++ L+ D A+ A+QGP A + + D+ ++ + + Sbjct: 122 KLYAWFTYLKRTIEQFTKLDLEIELKTYDIAMFAVQGPKARDLAKDLFGIDINEMWWFQA 181 Query: 208 AVMEVFGVSGCRVTRCGYTGEDGVEISVPVAG--------------AVHLATAILKNP-- 251 +E+ G+ ++R GYTGE+G E+ + A A+H+ IL+ Sbjct: 182 RWVELDGIK-MLLSRSGYTGENGFEVYIEDANPYHPDESKRGEPEKALHVWERILEEGKK 240 Query: 252 -EVKLAGLAARDSLRLEAGLCLYGNDIDE---------HTTPVEGSLSWTLGKRRRAAMD 301 +K GL ARD+LRLEAG LYGN+ E TP++ +L + + + D Sbjct: 241 YGIKPCGLGARDTLRLEAGYTLYGNETKELQLLSTDIDEVTPLQANLEFAIYWDK----D 296 Query: 302 FPGAKVIVPQLKGRVQRRRV--GLMCEGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKN 359 F G ++ Q + V R+ V ++ +G P + N G IG VTSG SP L Sbjct: 297 FIGKDALLKQKERGVGRKLVHFKMIDKGIPREGYKVYAN--GEMIGEVTSGTLSPLLNVG 354 Query: 360 VAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTNYYTL 402 + + +V EY++PG + VE+R +++ AV PF Y L Sbjct: 355 IGIAFVKEEYAKPGIEIEVEIRGQRKKAVTVTPPFYDPKKYGL 397 >3GIR-A nrPDB Length = 393 Score = 394 bits (1013), Expect = e-110, Method: Composition-based stats. Identities = 150/369 (40%), Positives = 200/369 (54%), Gaps = 11/369 (2%) Query: 33 LRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILGS 92 L+ PLY+ H G K AFAGW +P+ Y HLHTR H LFD+SHM + G Sbjct: 33 LKTLPLYELHEKAGAKFGAFAGWRMPLTYPLGVLKEHLHTRAHAGLFDISHMKLIAVEGP 92 Query: 93 DRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 V+ + + D A L+ Q S NE GILDDLI+T +E +V+NAG + D Sbjct: 93 KAVEFLSYALPVDAALLKIGQSRYSYLLNERAGILDDLILTRLAECRFMLVANAGNAQAD 152 Query: 153 LALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSAVMEV 212 A ++ + + Q + L+ LLALQGP AA VL +L FM + Sbjct: 153 FAELEKRAFGFECQ-----VIALERVLLALQGPQAAAVLADA-GLPGNELLFMQGFEPQ- 205 Query: 213 FGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEAGLCL 272 +TR GYTGEDG EI++P+ A LA +L + V+ GLAARDSLRLEAGLCL Sbjct: 206 ---QDWFITRSGYTGEDGFEIALPIGCARALAEKLLGDSRVEWVGLAARDSLRLEAGLCL 262 Query: 273 YGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEG-APMR 331 +GNDI TTP++ +L+W + K R F GAK + L+ R RVGL + P+R Sbjct: 263 HGNDITPDTTPIDAALTWAVPKNVREKAQFYGAKAFLESLQKGPSRCRVGLKPQTRQPIR 322 Query: 332 AHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSK 391 A + + + EG +IG VTSG PS VAMGYVP + GT + E+R K+ V Sbjct: 323 AGAVLFDNEGNRIGVVTSGGFGPSFDGPVAMGYVPVAWKVEGTEVFTELRGKKIALSVHS 382 Query: 392 MPFVPTNYY 400 +PFV Y+ Sbjct: 383 LPFVEQRYF 391 >1WOR-A nrPDB Length = 364 Score = 393 bits (1010), Expect = e-110, Method: Composition-based stats. Identities = 123/370 (33%), Positives = 190/370 (51%), Gaps = 21/370 (5%) Query: 33 LRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILGS 92 ++RTPL++ H+ G KMV FAGW +P+ Y S + + R+ +FDVSHM + + G Sbjct: 1 MKRTPLFEKHVELGAKMVDFAGWEMPLYYT-SIFEEVMAVRKSVGMFDVSHMGEFLVKGP 59 Query: 93 DRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKD 152 + V ++ L+ D + L + S+ NE GGI+DDL+V S +V NA EKD Sbjct: 60 EAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALMVVNAANIEKD 119 Query: 153 LALMQDKVRELQNQGRDVGLEVLD----NALLALQGPTAAQVLQAGVADDLRKLPFMTSA 208 ++ + ++ +EV + AL+A QGP A + LQ V D L ++ + + Sbjct: 120 FNWIK-------SHSKNFDVEVSNISDTTALIAFQGPKAQETLQELVEDGLEEIAYYSFR 172 Query: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATA---ILKNPEVKLAGLAARDSLR 265 V GV V+R GYTGEDG E+ + A + A +L+ + + AGL ARD R Sbjct: 173 KSIVAGVE-TLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKIDGRPAGLGARDVCR 231 Query: 266 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 325 LEA LYG D+DE+T P E LSW + + DF G + ++ + +V+R+ V L Sbjct: 232 LEATYLLYGQDMDENTNPFEVGLSWVVKLNK----DFVGKEALLKAKE-KVERKLVALEL 286 Query: 326 EGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQ 385 G + + G ++G +TSG SP+L K++A+ V + +V K Sbjct: 287 SGKRIARKGYEVLKNGERVGEITSGNFSPTLGKSIALALVSKSVKIGDQLGVVFPGGKLV 346 Query: 386 MAVVSKMPFV 395 A+V K PF Sbjct: 347 EALVVKKPFY 356 >1YX2-A nrPDB Length = 365 Score = 389 bits (999), Expect = e-108, Method: Composition-based stats. Identities = 124/374 (33%), Positives = 193/374 (51%), Gaps = 18/374 (4%) Query: 29 AQEVLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTK 88 + +L+RTPL+D + +GGK + F GW LPVQ+ S H R LFDVSHM + + Sbjct: 1 SNAMLKRTPLFDLYKEYGGKTIDFGGWELPVQFS-SIKKEHEAVRTAAGLFDVSHMGEVE 59 Query: 89 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC 148 + G+D + ++ L+ D++ L P + + GG +DDL++ E +V NA Sbjct: 60 VSGNDSLSFLQRLMTNDVSALTPGRAQYTAMCYPDGGTVDDLLIYQKGENRYLLVINASN 119 Query: 149 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA 208 +KDLA M++ + + ALLA+QGP A +L+ D+ L A Sbjct: 120 IDKDLAWMKEHAAGDVQ----IDNQSDQIALLAVQGPKAEAILKNLTDADVSALKPF--A 173 Query: 209 VMEVFGVSGCR--VTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVK---LAGLAARDS 263 ++ +SG + ++R GYTGEDG EI A+H+ I+ + GL ARD+ Sbjct: 174 FIDEADISGRKALISRTGYTGEDGYEIYCRSDDAMHIWKKIIDAGDAYGLIPCGLGARDT 233 Query: 264 LRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGL 323 LR EA + LYG ++ TP+E + + + ++ + DF G V+ Q + +R+ VGL Sbjct: 234 LRFEANIPLYGQELTRDITPIEAGIGFAVKHKKES--DFFGKSVLSEQKENGAKRKLVGL 291 Query: 324 MC--EGAPMRAHSPILNMEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVR 381 +G P + N G +G VT+G SP+L KNV + + E S GT++ VE+R Sbjct: 292 EMIEKGIPRHGYEVFQN--GKSVGKVTTGTQSPTLGKNVGLALIDSETSEIGTVVDVEIR 349 Query: 382 RKQQMAVVSKMPFV 395 +K A V K PF Sbjct: 350 KKLVKAKVVKTPFY 363 >3A8J-A nrPDB Length = 364 Score = 360 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 117/373 (31%), Positives = 189/373 (50%), Gaps = 25/373 (6%) Query: 32 VLRRTPLYDFHLAHGGKMVAFAGWSLPVQYRDSHTDSHLHTRQHCSLFDVSHMLQTKILG 91 + ++TPLY+ H G +MV F GW +P+ Y S D H R +FDVSHM + G Sbjct: 1 MAQQTPLYEQHTLCGARMVDFHGWMMPLHY-GSQIDEHHAVRTDAGMFDVSHMTIVDLRG 59 Query: 92 SDRVKLMESLVVGDIAEL-RPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWE 150 S + + L+ D+A+L + + S N +GG++DDLIV +E +V N+ E Sbjct: 60 SRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATRE 119 Query: 151 KDLALMQDKVRELQNQGRDVGLEVL---DNALLALQGPTAAQVLQAGVADDLRKLPFMTS 207 KDL+ + G+E+ D +++A+QGP A A + +D ++ Sbjct: 120 KDLSW-------ITQHAEPFGIEITVRDDLSMIAVQGPNAQA-KAATLFNDAQRQA--VE 169 Query: 208 AVMEVFGVS--GCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLR 265 + FGV + GYTGE G EI++P A A+++ VK GL ARD+LR Sbjct: 170 GMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAG-VKPCGLGARDTLR 228 Query: 266 LEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMC 325 LEAG+ LYG ++DE +P+ ++ WT+ A DF G + + Q + ++ +M Sbjct: 229 LEAGMNLYGQEMDETISPLAANMGWTIA-WEPADRDFIGREALEVQREHGTEKLVGLVMT 287 Query: 326 EGAPMRAHSPI--LNMEGTK-IGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRR 382 E +R P+ + +G + G +TSG SP+L ++A+ VP G +V++R Sbjct: 288 EKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEG---IGETAIVQIRN 344 Query: 383 KQQMAVVSKMPFV 395 ++ V+K FV Sbjct: 345 REMPVKVTKPVFV 357 >2GAG-A nrPDB Length = 965 Score = 355 bits (912), Expect = 1e-98, Method: Composition-based stats. Identities = 82/392 (20%), Positives = 145/392 (36%), Gaps = 34/392 (8%) Query: 34 RRTPLYDFHLAHGGKMVAFAGWSLPVQYRDS-------HTDSHLHTRQHCSLFDVSHMLQ 86 R T ++ +HL+HG + W P Y + R + D + + + Sbjct: 575 RITAMHSWHLSHGAEFEDVGQWKRPWYYPQAGETMDQAVYRESKAVRDSVGMLDATTLGK 634 Query: 87 TKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNA 146 +I G D + + + +L+ G + G I DD + +E + + Sbjct: 635 IEIRGKDAAEFLNRIYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLLHTTT 694 Query: 147 GCWEKDLALMQDKVRELQNQGRDVGLEVL----DNALLALQGPTAAQVLQAG-VADDLRK 201 G L +++ LQ + D+ + A +A+ GP + V+ D+ Sbjct: 695 GGAADVLDWLEEW---LQTEWPDLDVTCTSVTEQLATVAVVGPRSRDVIAKLASTVDVSN 751 Query: 202 LPFMTSAVMEVFGVSGC--RVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLA 256 F A +V SG R++R ++GE EI+VP + + + E + Sbjct: 752 EGFKFMAFKDVVLDSGIEARISRISFSGELAFEIAVPAWHGLRVWEDVYAAGEEFNITPY 811 Query: 257 GLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRV 316 G LR E G + G D D TP + + W + K + DF G + R Sbjct: 812 GTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVVSKLK----DFIGNRSYSRADNARE 867 Query: 317 QRRRVGLMC---------EGAPMRAHSPILNMEGT-KIGTVTSGCPSPSLKKNVAMGYVP 366 R+++ + EGA + A + + T G VTS SP+L + + + Sbjct: 868 DRKQLVSVLPVDKSLRLPEGAALVASDALASEGITPMEGWVTSSYDSPNLGRTFGLALIK 927 Query: 367 CEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTN 398 +R G +L V + VVS+ Sbjct: 928 NGRNRIGEVLKTPVGDQLVDVVVSETVLYDPE 959 >1VRQ-A nrPDB Length = 964 Score = 354 bits (909), Expect = 3e-98, Method: Composition-based stats. Identities = 78/392 (19%), Positives = 140/392 (35%), Gaps = 34/392 (8%) Query: 34 RRTPLYDFHLAHGGKMVAFAGWSLPVQYRD-------SHTDSHLHTRQHCSLFDVSHMLQ 86 R T ++ +HLAHG K W P Y + R + D S + + Sbjct: 574 RLTAMHPWHLAHGAKFEDVGQWKRPWYYPQDGESMDEAVYRECKAVRDSVGMLDASTLGK 633 Query: 87 TKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNA 146 +I G D + + + +L+ G + G I DD + +E + + Sbjct: 634 IEIRGKDAAEFLNRMYTNGYTKLKVGMGRYGVMCKADGMIFDDGVTLRLAEDRFLMHTTT 693 Query: 147 GCWEKDLALMQDKVRELQNQGRDVGLEVL----DNALLALQGPTAAQVLQAG-VADDLRK 201 G L +++ LQ + ++ + A +A+ GP + V+ + D+ Sbjct: 694 GGAADVLDWLEEW---LQTEWPELDVTCTSVTEQLATVAVVGPRSRDVIAKLASSLDVSN 750 Query: 202 LPFMTSAVMEVFGVSGC--RVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLA 256 F A +V SG R++R ++GE EI++P + + + + + Sbjct: 751 DAFKFMAFQDVTLDSGIEARISRISFSGELAFEIAIPAWHGLQVWEDVYAAGQEFNITPY 810 Query: 257 GLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRV 316 G LR E G + G D D TP + + W + K + DF G + + R Sbjct: 811 GTETMHVLRAEKGFIIVGQDTDGTVTPQDAGMEWVVSKLK----DFVGKRSFSREDNVRE 866 Query: 317 QRRRVG--------LMCEGAPMRAHSPILNMEGT--KIGTVTSGCPSPSLKKNVAMGYVP 366 R+ + L + + EG G VT SP+L + + + Sbjct: 867 DRKHLVSVLPVDSSLRLAEGAALVAADAVASEGVTPMEGWVTHAYNSPALGRTFGLALIK 926 Query: 367 CEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTN 398 +R G +L V + VS + Sbjct: 927 NGRNRIGEVLKTPVDGQLVDVQVSDLVLFDPE 958 >5L46-A nrPDB Length = 841 Score = 335 bits (858), Expect = 3e-92, Method: Composition-based stats. Identities = 100/394 (25%), Positives = 166/394 (42%), Gaps = 41/394 (10%) Query: 34 RRTPLYDFHLAHGGKMVAFAGWSLPVQ---------YRDSHTDSHL---------HTRQH 75 R + LY L M AGW P YR S ++ Q Sbjct: 443 RVSGLYQR-LESKCSMGFHAGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQR 501 Query: 76 CSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNT 135 ++ D+S + I G D ++L++ L I + +S G + +L V++ Sbjct: 502 VAVTDLSPFGKFNIKGQDSIRLLDHLFANVI--PKVGFTNISHMLTPKGRVYAELTVSHQ 559 Query: 136 SEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQA 193 S G +++ +G DL +++ E G DV ++ + + L L + GP A +VLQ Sbjct: 560 SPGEFLLITGSGSELHDLRWIEE---EAVKGGYDVEIKNITDELGVLGVAGPQARKVLQK 616 Query: 194 GVADDLRK--LPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNP 251 ++DL F+ + ++V + R YTGE G E+ +V L AI+ Sbjct: 617 LTSEDLSDDVFKFLQTKSLKVSNIP-VTAIRISYTGELGWELYHRREDSVALYDAIMNAG 675 Query: 252 E---VKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVI 308 + + G A ++LRLE +G +++ T P+E L + + + A DF G + + Sbjct: 676 QEEGIDNFGTYAMNALRLEKAFRAWGLEMNCDTNPLEAGLEYFVKLNKPA--DFIGKQAL 733 Query: 309 VPQLKGRVQRRRVGLMCEGAPMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGY 364 ++RR V L P N G +G TSG S S++K++A Y Sbjct: 734 KQIKAKGLKRRLVCL---TLATDDVDPEGNESIWYNGKVVGNTTSGSYSYSIQKSLAFAY 790 Query: 365 VPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTN 398 VP + S G + VE+ K AV+ + P V T Sbjct: 791 VPVQLSEVGQQVEVELLGKNYPAVIIQEPLVLTE 824 >1PJ5-A nrPDB Length = 830 Score = 333 bits (855), Expect = 5e-92, Method: Composition-based stats. Identities = 91/410 (22%), Positives = 156/410 (38%), Gaps = 49/410 (11%) Query: 33 LRRTPLYDFHLAHGGKMVAFAGWSLPVQY------------------RDSHTD------- 67 LR +P + H G + GW P + RD+ + Sbjct: 430 LRVSPFHARHKELGAFFLEAGGWERPYWFEANAALLKEMPAEWLPPARDAWSGMFSSPIA 489 Query: 68 --SHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGG 125 TR +++D++ + + ++ G +KL++ L D+A+ +P T +L + AGG Sbjct: 490 AAEAWKTRTAVAMYDMTPLKRLEVSGPGALKLLQELTTADLAK-KPGAVTYTLLLDHAGG 548 Query: 126 ILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQDKVRELQNQGRDVG-LEVLDNA----LL 180 + D+ V SE + +N D A + R G ++V D + Sbjct: 549 VRSDITVARLSEDTFQLGANGNI---DTAYFERAARHQTQSGSATDWVQVRDTTGGTCCI 605 Query: 181 ALQGPTAAQVLQAGVADDLRK--LPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVA 238 L GP A ++ DD L + + + + G+ R Y GE G E+ Sbjct: 606 GLWGPLARDLVSKVSDDDFTNDGLKYFRAKNVVIGGIP-VTAMRLSYVGELGWELYTSAD 664 Query: 239 GAVHLATAILKNPE---VKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKR 295 L A+ + + V AG AA SLRLE G +G D+ P E L + + Sbjct: 665 NGQRLWDALWQAGQPFGVIAAGRAAFSSLRLEKGYRSWGTDMTTEHDPFEAGLGFAV--- 721 Query: 296 RRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAP--MRAHSPILNMEGTKIGTVTSGCPS 353 + A F G + + + RR L + + P+ E +G VTS Sbjct: 722 KMAKESFIGKGALEGRTEEASARRLRCLTIDDGRSIVLGKEPVFYKE-QAVGYVTSAAYG 780 Query: 354 PSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFVPTNYYTLK 403 ++ K +A Y+P S G + +E ++ A V++ P L+ Sbjct: 781 YTVAKPIAYSYLPGTVS-VGDSVDIEYFGRRITATVTEDPLYDPKMTRLR 829 >4P9S-A nrPDB Length = 848 Score = 332 bits (851), Expect = 2e-91, Method: Composition-based stats. Identities = 91/375 (24%), Positives = 155/375 (41%), Gaps = 40/375 (10%) Query: 53 AGWSLPVQ---------YRDSHTDSHL---------HTRQHCSLFDVSHMLQTKILGSDR 94 AGW P YR S ++ Q + D+S + I G D Sbjct: 462 AGWEQPHWFYKPGQDTQYRPSFRRTNWFEPVGSEYKQVMQRVGVIDLSPFGKFNIKGQDS 521 Query: 95 VKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGCWEKDLA 154 +L++ L I + +S G + +L V++ S G +++ +G DL Sbjct: 522 TQLLDHLCANVI--PKVGFTNISHMLTPRGRVYAELTVSHQSPGEFLLITGSGSELHDLR 579 Query: 155 LMQDKVRELQNQGRDVGLEVLDNAL--LALQGPTAAQVLQAGVADDLRK--LPFMTSAVM 210 +++ G DV + + + L L + GP A +VLQ ++DL F+ + + Sbjct: 580 WIEEAA---VRGGYDVEIRNITDELGVLGVAGPYARRVLQKLTSEDLSDDVFKFLQTKSL 636 Query: 211 EVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPE---VKLAGLAARDSLRLE 267 ++ + R YTGE G E+ + L I+ + + G A ++LRLE Sbjct: 637 KISDIP-VTAIRISYTGELGWELYHRREDSAALYERIMNAGQEEGIDNFGTYALNALRLE 695 Query: 268 AGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEG 327 +G++++ T P+E L + + + A +F G + + ++RR V L Sbjct: 696 KAFRAWGSEMNCDTNPLEAGLDYFIKLNKPA--NFTGKQALKQIKAKGLKRRLVCL---T 750 Query: 328 APMRAHSPILN----MEGTKIGTVTSGCPSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRK 383 P N +G IG TSG S S++K++A YVP E S G + VE+ K Sbjct: 751 LATDNVDPEGNESVWYKGKVIGNTTSGSYSYSIQKSLAFAYVPVELSEVGQQVEVELLGK 810 Query: 384 QQMAVVSKMPFVPTN 398 A + + P V T Sbjct: 811 NYPATIIQEPLVLTE 825 >3TFJ-A nrPDB Length = 369 Score = 293 bits (750), Expect = 9e-80, Method: Composition-based stats. Identities = 62/342 (18%), Positives = 136/342 (39%), Gaps = 23/342 (6%) Query: 63 DSHTDSHLHTRQHCSLFDVSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNE 122 S DS+ H ++H ++DV+ Q +I G D +L++ + D+++ + + +E Sbjct: 42 GSIEDSYKHLKEHVQIWDVAAERQVEISGKDSAELVQLMTCRDLSKSKIGRCYYCPIIDE 101 Query: 123 AGGILDDLIVTNTSEGHLYVV---SNAGCWEKDLALMQDKVRELQNQGRDVGLEVLDNA- 178 G +++D +V E ++ S+ + K LA G +++++ Sbjct: 102 NGNLVNDPVVLKLDENKWWISIADSDVIFFAKGLA-----------SGHKFDVKIVEPVV 150 Query: 179 -LLALQGPTAAQVLQAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVP- 236 ++A+QGP + +++ + +L F + G + R G++ + G E+ V Sbjct: 151 DIMAIQGPKSFALMEKVFGKKITELKFFGFDYFDFEGTKHL-IARSGWSKQGGYEVYVEN 209 Query: 237 VAGAVHLATAILK-NPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKR 295 L + + E + R+E+ L YGND D + P E + Sbjct: 210 TQSGQKLYDHLFEVGKEFNVGPGCPNLIERIESALLSYGNDFDNNDNPFECGFDQYVSL- 268 Query: 296 RRAAMDFPGAKVIVPQLKGRVQRRR--VGLMCEGAPMRAHSPILNMEGTKIGTVTSGCPS 353 + ++F G + + Q++ V + + + I + IG + S C S Sbjct: 269 -DSDINFLGKEKLKEIKLKGPQKKLRGVKIDIKEISLTGSKNIYDENNNVIGELRSACYS 327 Query: 354 PSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKMPFV 395 P +K + + + + +++ V +PF+ Sbjct: 328 PHFQKVIGIAMIKKSHWEASQGFKIQINDNTINGNVCDLPFI 369 >5X1I-A nrPDB Length = 474 Score = 193 bits (491), Expect = 1e-49, Method: Composition-based stats. Identities = 78/390 (20%), Positives = 121/390 (31%), Gaps = 81/390 (20%) Query: 63 DSHTDSHLHTRQHCSLFD-VSHMLQTKILGSDRVKLMESLVVGDIAELRPNQGTLSLFTN 121 + R LFD HM+ I G D +KL+ ++ PN+ + Sbjct: 42 SNWRTEQWAWRNSAVLFDQTHHMVDLYIRGKDALKLLSDTMINSPKGWEPNKAKQYVPVT 101 Query: 122 EAGGILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQ------DKVRELQNQGRDVGLEVL 175 G ++ D I+ +E V A + Q D V + ++ R +G V Sbjct: 102 PYGHVIGDGIIFYLAEEEFVYVGRAPAANWLMYHAQTGGYNVDIVHDDRSPSRPMGKPVQ 161 Query: 176 DNAL-LALQGPTAAQVLQAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEIS 234 + +QGP A V++ L KL F A M + G+ R R G G G+EI Sbjct: 162 RISWRFQIQGPKAWDVIEKLHGGTLEKLKFFNMAEMNIAGMK-IRTLRHGMAGAPGLEIW 220 Query: 235 VPVAGAVHLATAILKNP---EVKLAGLAARDSLRLEAGLC------LYGNDI-------- 277 P AIL+ + G A S LE+G +Y D Sbjct: 221 GPYETQEKARNAILEAGKEFGLIPVGSRAYPSNTLESGWIPSPLPAIYTGDKLKAYREWL 280 Query: 278 ---------------------DEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRV 316 D + P E + DF G + + Sbjct: 281 PANSYEASGAIGGSFVSSNIEDYYVNPYEIGYGPFVKF----DHDFIGRDAL-EAIDPAT 335 Query: 317 QRRRVGLMCEGAPM----------------------------RAHSPILNMEGTKIGTVT 348 QR++V L G M +L+ G +G Sbjct: 336 QRKKVTLAWNGDDMAKIYASLFDTEADAHYKFFDLPLANYANTNADAVLDAAGNVVGMSM 395 Query: 349 SGCPSPSLKKNVAMGYVPCEYSRPGTMLLV 378 S + K+ +++ + E GT L V Sbjct: 396 FTGYSYNEKRALSLATIDHEIP-VGTELTV 424 >1NRK-A nrPDB Length = 328 Score = 45.1 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 41/263 (15%), Positives = 83/263 (31%), Gaps = 16/263 (6%) Query: 89 ILGSDRVKLMESLVVGDIAELRPNQGTLSLFTNEAGGILDDLIVTNTSEGHLYVVSNAGC 148 I G+D K M+ V D++++ +Q L+ + G + +L + +G ++ + Sbjct: 35 ITGADSEKYMQGQVTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVR 94 Query: 149 WEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVLQAGVADDLRKLPFMTSA 208 + L + V D + LL + G A L ++ + S Sbjct: 95 EPQLTELKKYAVFSKVTIAPD-----DERVLLGVAGFQARAALANLFSE-------LPSK 142 Query: 209 VMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNPEVKLAGLAARDSLRLEA 268 +V + + E I A A L + E+ + +L +EA Sbjct: 143 EKQVVKEGATTLLWFEHPAER-FLIVTDEATANMLTDKLRGEAELNNS--QQWLALNIEA 199 Query: 269 GLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGA 328 G + P +L LG + G +++ +R + L+ A Sbjct: 200 GFPVIDAANSGQFIPQATNL-QALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSA 258 Query: 329 PMRAHSPILNMEGTKIGTVTSGC 351 + +G Sbjct: 259 SRLPEAGEDLELKMGENWRRTGT 281 >6QE4-A nrPDB Length = 327 Score = 33.2 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 44/300 (14%), Positives = 94/300 (31%), Gaps = 57/300 (19%) Query: 87 TKILGSDRVKLMESLVVGDIAELRPNQGT--------LSLFTNEAGGILDDLIVTNTSEG 138 ++ G D + L+ ++ P + F N G L D+I+ E Sbjct: 30 LRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEH 89 Query: 139 H----LYVVSNA---GCWEKDLALMQDKVRELQNQGRDVGLEVLDNALLALQGPTAAQVL 191 + ++ G +K LAL + + + ++ + + + P A Sbjct: 90 SEVSGFLLECDSSVQGALQKHLALYRIRRKVTVEPHPELRVWAVLPS-----SPEA---- 140 Query: 192 QAGVADDLRKLPFMTSAVMEVFGVSGCRVTRCGYTGEDGVEISVPVAGAVHLATAILKNP 251 +A ++ + + R T G + G + P Sbjct: 141 -------------CGAASLQERAGAAAILIRDPRTARMGWRLLTQDEGPALV-------P 180 Query: 252 EVKLAGLAARDSLRLEAGLCLYGNDIDEHTT-PVEGSLSWTLGKRRRAAMDFPGAKVIVP 310 +L L R G+ D+ P+E +L++ + + G ++ Sbjct: 181 GGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAF-MNGVSFTKGCYIGQELTAR 239 Query: 311 QLKGRVQRRRVGLM--CEGAPMRAHSP---ILNMEGTKIGTVTSGCPSPSLKKNVAMGYV 365 V R+R+ + + P +P +L G +G +G + NV + + Sbjct: 240 THHMGVIRKRLFPVRFLDPLPTSGITPGATVLTASGQTVGKFRAG------QGNVGLALL 293 >1YPF-A nrPDB Length = 336 Score = 31.2 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 35/247 (14%), Positives = 83/247 (33%), Gaps = 44/247 (17%) Query: 107 AELRPNQGTLSLFTNEAGG--ILDDLIVTNTSEGHLYVVSNAGCWEKDLALMQDKVRELQ 164 + + L A I+D+ I T +E + + + + EK ++ ++D Sbjct: 36 TTVTLGKHKFKLPVVPANMQTIIDERIATYLAENNYFYIMHRFQPEKRISFIRDMQSRGL 95 Query: 165 NQGRDVGLEVLDNALLA---------------------------LQG-----PTAAQVLQ 192 VG++ + + +Q P + + Sbjct: 96 IASISVGVKEDEYEFVQQLAAEHLTPEYITIDIAHGHSNAVINMIQHIKKHLPESFVIAG 155 Query: 193 AG-VADDLRKLPFMTSAVMEVFGVSG---CRVTRCGYTGEDGVEISVPVAGAVHLATAIL 248 + +R+L + +V G + G+ G G +++ A + I+ Sbjct: 156 NVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGF-GTGGWQLAALRWCAKAASKPII 214 Query: 249 KNPEVKLAGLAARDSLRLEAGLCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVI 308 + ++ G A+ S+R A + + G+ H E S T+ K + ++ G+ Sbjct: 215 ADGGIRTNGDVAK-SIRFGATMVMIGSLFAGH----EESPGETIEKDGKLYKEYFGSASE 269 Query: 309 VPQLKGR 315 + + + Sbjct: 270 FQKGEKK 276 >3H1Q-A nrPDB Length = 272 Score = 30.1 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 42/119 (35%), Gaps = 8/119 (6%) Query: 277 IDEHTTPVEGSLSWTLGKRRRAAMDFPGAKVIVPQLKGRVQRRRVGLMCEGAPMRAHSPI 336 D+ PV G+L W + +D+ GA IV +LK +V+R +G A Sbjct: 45 TDQEGIPVAGALKWASVVKDGLVVDYIGAIQIVRELKAKVER-LLGSELFQAATAIPPGT 103 Query: 337 LNMEGTKIGTVTSGC---PSPSLKKNVAMGYVPCEYSRPGTMLLVEVRRKQQMAVVSKM 392 + G V +G + + VA ++V++ V + Sbjct: 104 VGRNAEACGHVVAGAGLELVTLVDEPVAAARALG----INDGIVVDIGGGTTGIAVIEK 158 >3F9U-A nrPDB Length = 172 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 6/35 (17%), Positives = 13/35 (37%) Query: 270 LCLYGNDIDEHTTPVEGSLSWTLGKRRRAAMDFPG 304 LY N++ + + + + +DF G Sbjct: 22 FNLYTNEVHAKFDDYDLGMEYARQHNKPVMLDFTG 56 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.130 0.330 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,612,549 Number of Sequences: 36641 Number of extensions: 503926 Number of successful extensions: 1480 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 27 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 1339 Number of HSP's gapped (non-prelim): 45 length of query: 403 length of database: 10,336,785 effective HSP length: 99 effective length of query: 304 effective length of database: 6,709,326 effective search space: 2039635104 effective search space used: 2039635104 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 60 (27.8 bits)