BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P48632 (815 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2W78-A nrPDB 1592 0.0 1XKH-A nrPDB 1422 0.0 3EFM-A nrPDB 473 e-133 6E4V-A nrPDB 392 e-109 1XKW-A nrPDB 373 e-103 5FP1-A nrPDB 126 3e-29 1FCP-A nrPDB 103 4e-22 6BPM-C nrPDB 89 1e-17 3QLB-A nrPDB 86 5e-17 5NEC-A nrPDB 84 3e-16 2A02-A nrPDB 70 3e-12 5FOK-A nrPDB 65 1e-10 6H7F-A nrPDB 63 5e-10 4EPA-A nrPDB 59 1e-08 2HDF-A nrPDB 58 2e-08 3CSL-A nrPDB 55 2e-07 1NQH-A nrPDB 51 2e-06 5FR8-A nrPDB 47 3e-05 3FHH-A nrPDB 47 3e-05 5FP2-A nrPDB 46 7e-05 5M9B-A nrPDB 39 0.009 2M5J-A nrPDB 38 0.014 1FEP-A nrPDB 38 0.014 4AD7-A nrPDB 32 1.3 6D6Q-B nrPDB 31 1.7 1PXT-A nrPDB 31 1.8 4HCX-A nrPDB 31 1.8 4B7O-A nrPDB 30 3.2 4AIP-A nrPDB 30 5.0 4W8Y-A nrPDB 30 5.2 2Z7X-A nrPDB 29 7.1 5EIX-A nrPDB 29 7.5 3GDB-A nrPDB 29 9.2 >2W78-A nrPDB Length = 772 Score = 1592 bits (4121), Expect = 0.0, Method: Compositional matrix adjust. Identities = 772/772 (100%), Positives = 772/772 (100%) Query: 44 QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTG 103 QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTG Sbjct: 1 QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTG 60 Query: 104 ASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPR 163 ASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPR Sbjct: 61 ASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPR 120 Query: 164 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIP 223 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIP Sbjct: 121 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIP 180 Query: 224 STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL 283 STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL Sbjct: 181 STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL 240 Query: 284 GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPD 343 GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPD Sbjct: 241 GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPD 300 Query: 344 TMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLE 403 TMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLE Sbjct: 301 TMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLE 360 Query: 404 HNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTG 463 HNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTG Sbjct: 361 HNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTG 420 Query: 464 PFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYID 523 PFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYID Sbjct: 421 PFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYID 480 Query: 524 DKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY 583 DKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY Sbjct: 481 DKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY 540 Query: 584 SVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENR 643 SVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENR Sbjct: 541 SVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENR 600 Query: 644 AEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKK 703 AEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKK Sbjct: 601 AEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKK 660 Query: 704 VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLV 763 VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLV Sbjct: 661 VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLV 720 Query: 764 DLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 DLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF Sbjct: 721 DLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 772 >1XKH-A nrPDB Length = 687 Score = 1422 bits (3680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 687/687 (100%), Positives = 687/687 (100%) Query: 129 ATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDV 188 ATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDV Sbjct: 1 ATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDV 60 Query: 189 MRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEV 248 MRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEV Sbjct: 61 MRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEV 120 Query: 249 LKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVR 308 LKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVR Sbjct: 121 LKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVR 180 Query: 309 GRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPL 368 GRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPL Sbjct: 181 GRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPL 240 Query: 369 FDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLG 428 FDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLG Sbjct: 241 FDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLG 300 Query: 429 AIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK 488 AIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK Sbjct: 301 AIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK 360 Query: 489 SYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLG 548 SYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLG Sbjct: 361 SYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLG 420 Query: 549 GRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLL 608 GRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLL Sbjct: 421 GRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLL 480 Query: 609 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKA 668 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKA Sbjct: 481 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKA 540 Query: 669 KTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKL 728 KTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKL Sbjct: 541 KTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKL 600 Query: 729 TVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT 788 TVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT Sbjct: 601 TVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT 660 Query: 789 YYTNIGFYTSASYGDPRNLMFSTRWDF 815 YYTNIGFYTSASYGDPRNLMFSTRWDF Sbjct: 661 YYTNIGFYTSASYGDPRNLMFSTRWDF 687 >3EFM-A nrPDB Length = 707 Score = 473 bits (1216), Expect = e-133, Method: Compositional matrix adjust. Identities = 270/714 (37%), Positives = 401/714 (56%), Gaps = 31/714 (4%) Query: 118 AEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNM 177 A + L A +T ++ +TE + +YT ++TAT L L+PRETPQS++VVTRQ + Sbjct: 3 ARTGNDIAQLPAISVTGREISDLTEGTNAYTTEAMSTATGLTLSPRETPQSVSVVTRQQI 62 Query: 178 DDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTL 237 +D GL + ++ PGI+V+ D++R ++ ARGF+I+NFQ+DG+ S + ++ G+T Sbjct: 63 EDQGLTDTGAILATAPGISVTRSDSNRYSFSARGFTIDNFQFDGLVSPILS-QWNYGSTD 121 Query: 238 SDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDV 297 D AIYD VE+++GATGL+TG+G+ A +N +RK+P EF GSWD R + D+ Sbjct: 122 MDAAIYDHVEIVRGATGLMTGSGNPSAAVNFVRKRPLREFAATFNASVGSWDYVRGDADI 181 Query: 298 SGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDP 357 S P+TE G +R R VAAY S++ + + +YG++ DL PDT+LT +YQ N Sbjct: 182 SVPITEDGRIRSRLVAAYSQGDSYVHFLDTRRRTFYGVVSADLTPDTVLTTSVEYQHNHS 241 Query: 358 KGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLD 417 G G FPLF S G+R D +RS N A W+ + T F +L H F N W + Sbjct: 242 NGFG--SGFPLFYSDGSRTDFNRSVANNAPWARQDTEATTYFVDLTHRFTNDWKLRAAYS 299 Query: 418 HKINGYHAPLGAIMGDWPAPDNSAKIVA-----QKYTGETKSNSLDIYLTGPFQFLGREH 472 H +G + G + PD I+A Y G + + L+ PF+ G H Sbjct: 300 H-TDGRYLMKHVYRGGY--PDRHTGIIAAPPAFSNYDGNLDRDDIHFSLSAPFEAFGLRH 356 Query: 473 ELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINW---------DGDIGKPDWG-TPSQYI 522 E+ +G + +H + + Y + F +W I +P W T S Sbjct: 357 EVALGWMSIDNHSDIQRY-AMVGPAPAIGSFFDWRRAGSHHHHHHHIQEPSWADTLSPAD 415 Query: 523 DDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVT----GLNPTIRESGRFIPYVGAVYD 578 D +T+Q G+Y+ RF + + L+L +G R D++ G R +F PY G YD Sbjct: 416 DVRTKQTGAYLVGRFALAEPLHLIVGDRWSDWKTKQMYFGSRREYRIKNQFTPYAGLTYD 475 Query: 579 LNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEI 638 +NDTY+ YASYT+IF PQ++ RD+S +L P + ++YE+G+K YL+GRLNTS A F+ Sbjct: 476 INDTYTAYASYTEIFQPQNA--RDTSGGILPPIKSKSYELGLKAAYLEGRLNTSAALFQT 533 Query: 639 HEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRD 698 ++N A+ +S P P + + AK +G + E SG++ P W + A YTH +D Sbjct: 534 RQDNLAQV-IPGSSIPGFPNMQASRAASGAKVEGIDLEASGQILPDWNIGASYTHFTTKD 592 Query: 699 DSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQE 758 SG ++T P+ LYT+Y+ GAL +LTVGGG WQ + +Q +PR E Q+ Sbjct: 593 ASGNPINTNHPRSLFKLYTTYRLPGALHRLTVGGGVDWQSRMYQAA-ASPRGNVE-VEQD 650 Query: 759 DYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTR 812 Y LV LMAR+ KLSA++NVNN+FDK YY IGFY+ +G PRN+M + R Sbjct: 651 SYALVSLMARFDFNKKLSATLNVNNLFDKKYYDQIGFYSQGWWGAPRNVMLNLR 704 >6E4V-A nrPDB Length = 693 Score = 392 bits (1006), Expect = e-109, Method: Compositional matrix adjust. Identities = 248/692 (35%), Positives = 372/692 (53%), Gaps = 45/692 (6%) Query: 147 YTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNN 206 Y+ + + T++ +T R+ PQS+T+V++Q M+D L + +VM +T GI+ S D+DR Sbjct: 24 YSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRAL 83 Query: 207 YYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATI 266 YY+RGF I+N+ DGIP T ++ G+ LSDMA+++RVEV++GATGL+TG G+ A I Sbjct: 84 YYSRGFQIDNYMVDGIP-TYFESRWNLGDALSDMALFERVEVVRGATGLMTGTGNPSAAI 142 Query: 267 NLIRKKPT-HEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHY 325 N++RK T EFKG V GSW+ R D+ PLTE G +R R V YQ+ S++D Y Sbjct: 143 NMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRY 202 Query: 326 ERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNG 385 + + + GI++ DL T L+ G +YQ D W G P +++ G+ N R+ + Sbjct: 203 NSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTW-GGLPRWNTDGSSNSYDRARSTA 261 Query: 386 AKWSSWEQYTRTVFANLEHNFANGWVG-------KVQLDHKINGYHAPL----GAIMGDW 434 W+ ++ VF L+ FA+ W +V+ D K+ A + G ++G + Sbjct: 262 PDWAYNDKEINKVFMTLKQQFADTWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPY 321 Query: 435 PAPDNSAKIVAQK--YTGETKSNSLDIYLTGPFQFLGREHELVVGTSAS------FSHWE 486 V +G+ K ++LD++ G ++ GR+H L+ G S S FS W Sbjct: 322 SNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLMFGGSYSKQNNRYFSSWA 381 Query: 487 GKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLF 546 + + F N++G+ + DW S DD T Y R + D L+L Sbjct: 382 NI-------FPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLI 434 Query: 547 LGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNK 606 LG R ++RV L ++ E PY G V+D+ND +S YASYT IF PQ+ RDSS K Sbjct: 435 LGARYTNWRVDTLTYSM-EKNHTTPYAGLVFDINDNWSTYASYTSIFQPQND--RDSSGK 491 Query: 607 LLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGI 666 L P G NYE+G+K ++++ RL T+LA F I ++N A+ P + T AYK + Sbjct: 492 YLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQSTG--TPIPGSNGET-AYKAV 548 Query: 667 KAK-TKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGAL 725 +KG E E++G + WQ+ G T I D+ G V+ P+ + ++TSY+ + Sbjct: 549 DGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRLP-VM 607 Query: 726 DKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQED--YWLVDLMARYQITDKLSASVNVNN 783 +LTVGGG WQ + VY + + + F E Y LVDL RYQ+T S NVNN Sbjct: 608 PELTVGGGVNWQNR----VYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNN 663 Query: 784 VFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 +FDKTY TN+ S YG PRN + + F Sbjct: 664 LFDKTYDTNVE--GSIVYGTPRNFSITGTYQF 693 >1XKW-A nrPDB Length = 665 Score = 373 bits (957), Expect = e-103, Method: Compositional matrix adjust. Identities = 241/690 (34%), Positives = 360/690 (52%), Gaps = 41/690 (5%) Query: 142 EDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYD 201 E + + P + T ++ L PRE PQS +V+ + ++ L ++D+ M+ G+TV + Sbjct: 1 ESTSATQPPGVTTLGKVPLKPRELPQSASVIDHERLEQQNLFSLDEAMQQATGVTVQPFQ 60 Query: 202 TDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGS 261 YY RGF +++F+ DG+P+ N S DMAIY+RVE+L+G+ GLL G G+ Sbjct: 61 LLTTAYYVRGFKVDSFELDGVPALLGNTASSP----QDMAIYERVEILRGSNGLLHGTGN 116 Query: 262 LGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSF 321 AT+NL+RK+P EF L AG WD YR+E+DV GPL+ SGNVRGRAVAAY+D+ F Sbjct: 117 PAATVNLVRKRPQREFAASTTLSAGRWDRYRAEVDVGGPLSASGNVRGRAVAAYEDRDYF 176 Query: 322 MDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRS 381 D ++ T + YG+ EFDL+PDT+LTVGA YQ D + P+ G+ +SR Sbjct: 177 YDVADQGTRLLYGVTEFDLSPDTLLTVGAQYQHIDSITN--MAGVPM-AKDGSNLGLSRD 233 Query: 382 FNNGAKWSSWEQYTRTVFANLEHNFANGWVGKV-----QLDHKINGYHAPLGAIMGDWPA 436 W ++ T F +LE GW GKV + D ++ Y GAI P Sbjct: 234 TYLDVDWDRFKWDTYRAFGSLEQQLGGGWKGKVSAEYQEADSRLR-YAGSFGAID---PQ 289 Query: 437 PDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNY 496 + +++ Y ++ SLD L GP + G HEL+ G + + + N Sbjct: 290 TGDGGQLMGAAYKFKSIQRSLDANLNGPVRLFGLTHELLGGVTYAQGETRQDTA-RFLNL 348 Query: 497 DNTTDDFINWDGD-IGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYR 555 NT + WD + +P G + T Q G Y R + + L L +GGR + Sbjct: 349 PNTPVNVYRWDPHGVPRPQIGQYTSPGTTTTTQKGLYALGRIKLAEPLTLVVGGRESWWD 408 Query: 556 VTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQ---DSWYRDSSNKLLEPDE 612 + +F PY G ++D +S Y SY +++ PQ +W +++ L P E Sbjct: 409 QDTPATRFKPGRQFTPYGGLIWDFARDWSWYVSYAEVYQPQADRQTW----NSEPLSPVE 464 Query: 613 GQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKG 672 G+ YE GIKGE DGRLN SLA F I EN +ED + P NP + G K +++G Sbjct: 465 GKTYETGIKGELADGRLNLSLAAFRIDLENNPQEDPDHPGPPNNP---FYISGGKVRSQG 521 Query: 673 YEAEISGELAPGWQVQAGYTH------KIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALD 726 +E E +G L P W + AGYT+ K ++DSG + ST+ P+ L L+++Y Sbjct: 522 FELEGTGYLTPYWSLSAGYTYTSTEYLKDSQNDSGTRYSTFTPRHLLRLWSNYDLPWQDR 581 Query: 727 KLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFD 786 + +VGGG + Q + + Y R Q Y LV++ Y+I + +A+VNVNN+FD Sbjct: 582 RWSVGGGLQAQ-SDYSVDY-----RGVSMRQGGYALVNMRLGYKIDEHWTAAVNVNNLFD 635 Query: 787 KTYYTNIGFYT-SASYGDPRNLMFSTRWDF 815 +TYY ++ + YG+PR+ S R F Sbjct: 636 RTYYQSLSNPNWNNRYGEPRSFNVSLRGAF 665 >5FP1-A nrPDB Length = 718 Score = 126 bits (317), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 182/716 (25%), Positives = 301/716 (42%), Gaps = 132/716 (18%) Query: 156 TRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNN---YYARGF 212 ++ V +TP+S++V+++Q ++D + + D +R PGIT+ A + N + RG+ Sbjct: 31 SKFVAPLLDTPKSVSVISKQLIEDTKVTTLADALRTVPGITLGAGEGGNPNGDRPFIRGY 90 Query: 213 SINNFQY-DGIP-STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIR 270 S + Y DGI ST++N +M ++VEV KG+ + GAGS+G +IN+I Sbjct: 91 SSESSMYIDGIRNSTSQN---------REMFAVEQVEVTKGSASAMGGAGSVGGSINMIS 141 Query: 271 K--KPTHEFKGHVELGAGSWDNY-RSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYER 327 K K +G V G DNY R LD + R + +K + E Sbjct: 142 KVAKKGDFLEGSVAAGT---DNYQRITLDGNKDFGNGIAARVAVLGHQNEKAGQSNGAEY 198 Query: 328 KTSVYYGILEFDLNPDTMLTVGADY-QDNDPKGSG---WSGSFPLFDSQGNRNDVSRSFN 383 K + F L+ T T+ Y Q +D SG W S L +QG +V + Sbjct: 199 KRVGIAPSITFGLDTPTRATLSYYYLQTDDKPDSGIPYWDSS--LGKAQGKPAEVKQ--- 253 Query: 384 NGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGD-------WPA 436 + W+ F E++ +G ++L+H + M W Sbjct: 254 --GTYYGWKDRD---FQKQENH-----IGTIKLEHDLTDNITITNTAMYAKSKNDYVWTN 303 Query: 437 PDNSAKIVAQKYT--------GETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK 488 PD+S V + ++++ + + LTG F +H VG S + K Sbjct: 304 PDDSKGNVGKGLVWHRLNSAITDSETFTDQLALTGKFDTGFLKHRFNVGAEYSKQKTD-K 362 Query: 489 SYWNLRN----------YDNTTDDFINWDGDIGKPDWGTPSQYID--------DKTRQLG 530 +N+ + Y + +D NW + P T ++D D T + Sbjct: 363 GGYNIIDAKGNVSSTGFYSDCSDLSTNWCTSLNGP---TQKPFVDRLQARPDFDATVEST 419 Query: 531 S-YMTARFNVTDDLNLFLGGRVVDYRV--------TGLNPTIRESGRFIPY-VGAVYDLN 580 S Y+ +T L LG R + + T + + F+ Y G + Sbjct: 420 SVYLLDNIEITPKWLLDLGLRWDKFEAEQNFLATSSAAAYTAKNNSDFVTYQAGITFKPT 479 Query: 581 DTYSVYASYTDIFMP--------QDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTS 632 + S+Y SY P +S +++N++++P+E Q +EIG K ++LD LN + Sbjct: 480 ENGSIYTSYATSASPVGLNAGWGDNSETINANNQMIDPEEAQTFEIGTKWDFLDNHLNLT 539 Query: 633 LAYFEIHEEN-RAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGY 691 A F ++N R + D PT TYA G ++K G+E ++GE+ W + AGY Sbjct: 540 AAIFRTEKQNTRVQID------PT----TYANVG-ESKVDGFELGLNGEITDKWNISAGY 588 Query: 692 TH---------KIIRDDSGKKVSTWE-------PQDQLSLYTSYKFKGALDKLTVGGGAR 735 T+ K R S + P+ +L+T+YK L +LTVG GA Sbjct: 589 TYLDSELTKNGKSCRSGKCTDQSIYNGNQMPNVPKQAATLWTTYK---VLPQLTVGAGAV 645 Query: 736 WQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYT 791 + K + V N ++W Y D MARY + + +N+NN+ DK Y+T Sbjct: 646 YSDKVYGDVAN---TKW----VPSYVRYDAMARYNVNKNVDLQLNINNLSDKRYFT 694 >1FCP-A nrPDB Length = 705 Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 167/715 (23%), Positives = 296/715 (41%), Gaps = 77/715 (10%) Query: 153 ATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDR--NNYYAR 210 AT T+ ++ PQSI+VVT + M ++ + + +TPG++V ++ R Sbjct: 16 ATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVSVGTRGASNTYDHLIIR 75 Query: 211 GFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIR 270 GF+ + + + G + + D + +R E+++G +L G S G +N++ Sbjct: 76 GFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVLYGKSSPGGLLNMVS 135 Query: 271 KKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTS 330 K+PT E V+ AG+ +++ D S L + G R + ++ E + Sbjct: 136 KRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDGVYSYRLTGLARSANAQQKGSEEQR- 194 Query: 331 VYYGIL-EFDLNPD--TMLTVGADYQDNDPKGSGWSGSFP---LFDSQGNRNDVSRSFNN 384 Y I F PD T T + +Q N+P+ +G+ G P + N + FN Sbjct: 195 --YAIAPAFTWRPDDKTNFTFLSYFQ-NEPE-TGYYGWLPKEGTVEPLPNGKRLPTDFNE 250 Query: 385 GAKWSSWEQYTRTVFANLEHNFANGWVGKVQL--------DHKINGYHA---PLGAIMGD 433 GAK +++ + + V + +H F + + + L + + GY P A Sbjct: 251 GAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLRFAENKTSQNSVYGYGVCSDPANAYSKQ 310 Query: 434 WP--APDNSAKIVAQKYT---GETKSNSLDIYLTGPFQFLGREHELVVGT---------S 479 AP + +A+KY + ++ S+D L F +H L+ G + Sbjct: 311 CAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQSKFATGDIDHTLLTGVDFMRMRNDIN 370 Query: 480 ASFSHWEGKSYWNLRNYDNTTDDF--INWDGDIGKPDWGTPSQY-IDDKTRQLGSYMTAR 536 A F + + NL N + +N D D D Y I +K +Q G Y+ + Sbjct: 371 AWFGYDDSVPLLNLYNPSHHHHHHGSVNTDFDFNAKDPANSGPYRILNKQKQTGVYVQDQ 430 Query: 537 FNVTDDLNLFLGGRVVDY-------RVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASY 589 D + + LGGR D+ RV G R+ +F G Y ++ + Y SY Sbjct: 431 AQW-DKVLVTLGGR-YDWADQESLNRVAGTTDK-RDDKQFTWRGGVNYLFDNGVTPYFSY 487 Query: 590 TDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDAL 649 ++ F P +D + + P +G+ YE+G+K D + + A + + + N D Sbjct: 488 SESFEPSSQVGKDGN--IFAPSKGKQYEVGVKYVPEDRPIVVTGAVYNLTKTNNLMADP- 544 Query: 650 YNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTH---KIIRDDSGKKVST 706 ++ +G + + +G E E L+ V YT+ + D + K + Sbjct: 545 -------EGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTP 597 Query: 707 WE-PQDQLSLYTSYK-FKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVD 764 + P+ SL+ Y F G L LT+G G R+ G S Y +P + F Y +VD Sbjct: 598 AQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSS----YGDPAN---SFKVGSYTVVD 650 Query: 765 LMARYQITDKLSASVN----VNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 + RY + A N VNN+FD+ Y + +G R ++ + + F Sbjct: 651 ALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVVATATFRF 705 >6BPM-C nrPDB Length = 727 Score = 88.6 bits (218), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 74/263 (28%), Positives = 117/263 (44%), Gaps = 39/263 (14%) Query: 573 VGAVYDLNDTYSVYASYT--------DIFMPQDSWYRDSSNKL-LEPDEGQNYEIGIKGE 623 GA+Y L + +VY +Y + F S +S+N+ +P + EIG K + Sbjct: 484 AGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQ 543 Query: 624 YLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAP 683 LD RL + A F EN E+ N TY+ G K + +GYE ++G + P Sbjct: 544 VLDKRLLLTAALFRTDIENEVEQ---------NDDGTYSQYG-KKRVEGYEISVAGNITP 593 Query: 684 GWQVQAGYTHKIIRDDSGKKVST-------WEPQDQLSLYTSYKFKGALDKLTVGGGARW 736 WQV GYT + +GK V+ + P+ +L++ Y+ A D ++VG GAR+ Sbjct: 594 AWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQ---ATDDISVGAGARY 650 Query: 737 QGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFY 796 G M + + E YW+ D Y++ L +NV N+FD Y +I Sbjct: 651 IGS---MHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASI--- 704 Query: 797 TSASY----GDPRNLMFSTRWDF 815 + Y G+PR + + F Sbjct: 705 NKSGYRYHPGEPRTFLLTANMHF 727 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 42/151 (27%), Positives = 76/151 (50%), Gaps = 14/151 (9%) Query: 164 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITV-----SAYDTDRNNYYARGFSINNFQ 218 +T +++TV++ Q + D G N+ D +++ PG+ + T + Y RG +N Sbjct: 37 DTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSI 96 Query: 219 Y-DGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEF 277 Y DGI R++G + +T + ++VEV+KG +G G + +IN+I K+P ++ Sbjct: 97 YIDGI----RDIGSVSRDTFNT----EQVEVIKGPSGTDYGRSAPTGSINMISKQPRNDS 148 Query: 278 KGHVELGAGSWDNYRSELDVSGPLTESGNVR 308 GS R LDV+ + ++ VR Sbjct: 149 GIDASASIGSAWFRRGTLDVNQVIGDTTAVR 179 >3QLB-A nrPDB Length = 748 Score = 86.3 bits (212), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 66/239 (27%), Positives = 110/239 (46%), Gaps = 18/239 (7%) Query: 122 DSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFG 181 D ++ L ++I++ Q + T Y + T+ + E PQSI+V+TR MD Sbjct: 58 DHALTLDTSVISATQPDSATGPQAGYVAKRSLSGTKTDASLSEIPQSISVITRDQMDAQQ 117 Query: 182 LNNIDDVMRHTPGI--TVSAYDTDRNNYYARGFSINN-FQYDGIPSTARNVGYSAGNTLS 238 + ++++ +R+T G+ +A + RGF + DG+ GNT Sbjct: 118 VQSVNEALRYTAGVQANTTAASQRFDTLSIRGFDVTTGMLRDGL----------KGNTAQ 167 Query: 239 ---DMAIY--DRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRS 293 + Y +R++VLKG +L G S G +N I K+P + V++ GS+D + Sbjct: 168 AWPKVEAYGLERIDVLKGPASVLFGQNSPGGVVNQISKRPLDKPFHEVQIQGGSFDRAQG 227 Query: 294 ELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADY 352 + D SGPL + G R V +D + DH + + + N DT LT+ ADY Sbjct: 228 QFDFSGPLDDEGQFLYRLVGLERDSGTQFDHIKDDKQYFAPSFTWKPNDDTSLTLLADY 286 Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 75/322 (23%), Positives = 123/322 (38%), Gaps = 44/322 (13%) Query: 514 DWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESG------ 567 D TP + Q+G Y +F + L +GGR D + + +SG Sbjct: 447 DPSTPFTNTVQRADQVGVYAQQQFTFDEHWVLTVGGRQ-DRSSARTDNRMNDSGSKQDDE 505 Query: 568 RFIPYVGAVYDLNDTYSVYASYTDIFMPQ--DSWYRDSSNKLLEPDEGQNYEIGIKGEYL 625 +F G VY ++ + Y SY+ F P ++Y +P + E+G+K + Sbjct: 506 KFTYRTGLVYLADNGLAPYISYSTSFDPVLGTNFY----GTPYKPTSAKQSEVGVKYQPP 561 Query: 626 DGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGW 685 +L+ F++ +EN D + +G E E LA G Sbjct: 562 GIDSYITLSLFDLTQENVLTTDPAQRLNKIQTG--------EINVRGIELEGKASLARGL 613 Query: 686 QVQAGYTH---KIIRD----DSGKKVSTWEPQDQLSLYTSYKF-KGALDKLTVGGGARWQ 737 + A T+ ++ + + GK+ T P+ SL+ Y +G L L G G R+ Sbjct: 614 DLLAALTYNDAEVSKSNNPLEKGKR-PTDTPEKMASLWADYTLPEGPLSGLGFGAGVRYI 672 Query: 738 GKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSAS------VNVNNVFDKTYYT 791 G + N R Y L+D Y + A+ VN N+ DK YY Sbjct: 673 GSTEADAANTQRV-------PSYTLLDAAVHYDFDKLIPAAKGLRLAVNATNLTDKHYYE 725 Query: 792 NIGFYTSASYGDPRNLMFSTRW 813 T+ S G R+++ S R+ Sbjct: 726 GCSL-TNCSAGYDRSVIASLRY 746 >5NEC-A nrPDB Length = 741 Score = 83.6 bits (205), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 90/316 (28%), Positives = 135/316 (42%), Gaps = 62/316 (19%) Query: 540 TDDLN----LFLGGRVVDYRVTGLNPTIRESGRFIP-------YVGAVYDLNDTYSVYAS 588 T DLN + +G R + T N +R + + G V+ S+YAS Sbjct: 440 TIDLNEQWQVNIGARFDSFETTAKNHGVRPATKLSDKSSFWNWQAGLVWKPVPNGSIYAS 499 Query: 589 YTDIFMPQDSWYR--DSSNKL--------LEPDEGQNYEIGIKGEYLDGRLNTSLAYFEI 638 Y P S D+SN + LEP+E NYE+G K + + RL S A F Sbjct: 500 YATSATPPGSMLDNGDTSNAVDGFAISNNLEPEETTNYELGTKWAFFNERLELSAAIF-- 557 Query: 639 HEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTH---KI 695 R ++D N++ TY G +++ G E SG+L W+V AGY++ ++ Sbjct: 558 ----RTDKD---NTRILVANQTYDNAG-QSRVDGVELSASGKLTEKWKVFAGYSYLDSEL 609 Query: 696 IRDDSGKKVSTWE----------------PQDQLSLYTSYKFKGALDKLTVGGGARWQGK 739 + D+GK P++ SL+T+Y K T+GGGA + K Sbjct: 610 V--DAGKAGRNGNVNASAASNNGNEMPNTPKNSFSLWTTYDI---FPKTTIGGGAFYVDK 664 Query: 740 SWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSA 799 + V N DYW D MA Y+++ + +NV NVFDK Y+ A Sbjct: 665 VYGDVGNT-------VYVPDYWRYDAMASYKLSKNVDFQLNVQNVFDKKYFDKAYAAHYA 717 Query: 800 SYGDPRNLMFSTRWDF 815 S R ++FST + F Sbjct: 718 SQAAGRTILFSTNFHF 733 Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 34/113 (30%), Positives = 56/113 (49%), Gaps = 12/113 (10%) Query: 164 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDR---NNYYARGFSINNFQY- 219 +TP+S+TVV +Q + D ++ D +R PGIT A + + + RGF + Y Sbjct: 49 DTPRSVTVVPKQVIKDTAAVSLQDALRTVPGITFGAGEGGNPTGDRPFIRGFDAQSDTYV 108 Query: 220 DGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKK 272 DG+ T G ++ +++EV KG G GS G ++NL+ K+ Sbjct: 109 DGVRDT--------GAQTREIFNLEQIEVSKGPNSAFGGRGSAGGSLNLVSKQ 153 >2A02-A nrPDB Length = 82 Score = 70.1 bits (170), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 33/79 (41%), Positives = 50/79 (63%) Query: 43 AQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGT 102 +QE DIP Q++ SALQ +Q D Q+LY PE++ RSSA+KG+ + ++ LL+GT Sbjct: 1 SQEWTLDIPAQSMNSALQALAKQTDTQLLYSPEDIGGLRSSALKGRHDLQSSLRILLQGT 60 Query: 103 GASVDFQGNAITISVAEAA 121 G GN +T++ + AA Sbjct: 61 GLRYQIDGNTVTVTASAAA 79 >5FOK-A nrPDB Length = 730 Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 49/197 (24%), Positives = 87/197 (44%), Gaps = 28/197 (14%) Query: 605 NKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAI-TYAY 663 N L+P+ +N E+G K + D L+ + A F + N ++ +P + T Sbjct: 521 NNGLDPERNRNLELGTKWAFFDDALSLNAALFRTDKTN---------ARVASPDVSTLQV 571 Query: 664 KGIKAKTKGYEAEISGELAPGWQVQAGYTH-------KIIRDDSGKKVSTWEPQDQLSLY 716 + + +G E +G+L W+V GYT+ ++ D G K+ Q+ +L+ Sbjct: 572 LDGEQRVQGVELGFNGKLTEKWKVFGGYTYLDSEIRKSTVKSDEGNKMPQ-TAQNNFTLW 630 Query: 717 TSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLS 776 T+Y L T+GGG + K + N+ YW D MA Y+++ + Sbjct: 631 TTYDL---LQNFTIGGGTTYVDKQYGNTANSTYI-------PSYWRYDAMASYKVSKNVD 680 Query: 777 ASVNVNNVFDKTYYTNI 793 +NV N+ DK Y+ + Sbjct: 681 LQLNVQNLTDKRYFDQV 697 Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 42/138 (30%), Positives = 65/138 (47%), Gaps = 10/138 (7%) Query: 164 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDR---NNYYARGFSINNFQYD 220 +TP+++TV+ +Q + D G + D +R TPGIT A + + + RGF N + D Sbjct: 48 DTPKTVTVIPQQVIKDTGALTLADALRTTPGITFGAGEGGNPAGDRPFIRGF---NAESD 104 Query: 221 GIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGH 280 R+V + +++EV KG TGAGS G ++NLI K + Sbjct: 105 TFLDGMRDVASQTREVFN----VEQIEVSKGPGSAYTGAGSTGGSLNLISKTAKQDNFTD 160 Query: 281 VELGAGSWDNYRSELDVS 298 GS R+ LDV+ Sbjct: 161 AGFTWGSDQTRRTTLDVN 178 >6H7F-A nrPDB Length = 706 Score = 62.8 bits (151), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 158/726 (21%), Positives = 279/726 (38%), Gaps = 104/726 (14%) Query: 142 EDSGSYTPGTIATATRLVLTPR----ETPQSITVVTRQNMDDFGLNNIDDVMRHT-PGI- 195 E +Y G +AT++ + +TP + T + ++D +I +V+ T P I Sbjct: 33 EQDDTYAGGQVATSSNVGFLGSKKFLDTPFNTISYTDKYIEDKQAKDITEVIAATDPSIY 92 Query: 196 TVSAYDTDRNNYYARGF--SINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGAT 253 T A NYY RG+ S N+ +G+ G + S ++ RVEVLKG + Sbjct: 93 TNGASGGWSENYYIRGYASSTNDMSMNGL------FGITPFYRTSP-EMFGRVEVLKGPS 145 Query: 254 GLLTG---AGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGR 310 LL G AGS+G T+NL+ K E + S + +DV E+ R Sbjct: 146 ALLNGMPPAGSVGGTVNLVTKYAADEPFARLTTTYMSDAQFGGHVDVGRRFGENKEFGVR 205 Query: 311 AVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFD 370 Y+D + ++ +++ ++ ++G D+Q G +D Sbjct: 206 INGMYRDGDAAVNDQSKESRLF--------------SLGLDWQ-----GENARVFVDAYD 246 Query: 371 SQGNRNDVSRSFNNGAK----------------WSSWEQYTRTVFANLEHNFANGWV--- 411 + + + V+R N W S E + E++F++ + Sbjct: 247 ALDHVDGVTRGVNVSTAVGIPKPPKADTLLSPDWGSVETKDKGAMIRGEYDFSDQLMAYA 306 Query: 412 --GKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLG 469 G+ ++K NG A G + + + + S D G F+ Sbjct: 307 AYGQSTTEYKYNGASA------GTITSSTGTLSSTLGQLAFDVDKKSADAGFKGKFETGS 360 Query: 470 REHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDD----- 524 +H+ V + ++H + + R +D I D P+WG ++ Sbjct: 361 VKHQWVA-NATYYNHTQDD--YGYRIIPGFSDPVITNIYD-PNPNWGPKPEFTPPFLFHS 416 Query: 525 --KTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGR--FIPYVGAVYDLN 580 T G T F D + L LG R + T T+ E+ + P V + Sbjct: 417 TLSTSSFGLADTLSF-AQDKVQLTLGLRHQTVKATSSVNTLPENAKSATTPGVALLIKAT 475 Query: 581 DTYSVYASYTDIFMPQDSWYRDSSN--KLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEI 638 D SVYA+Y + D +SN ++ P + + E+G+K + G +L+ FEI Sbjct: 476 DKISVYANYIEGLTKGDQAPATASNPGEIFPPQKTKQQELGLKVDL--GTFAHTLSAFEI 533 Query: 639 HEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTH---KI 695 + + L SK N T+ G + + +G E G ++ G+T+ ++ Sbjct: 534 TKPS----SYLDPSKLVNNLPTFVSDG-EQRNRGIEWSFFGSPIEHVRLMGGFTYLDPEL 588 Query: 696 IRDDSGKK---VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRW 752 + SG + P++Q L + + A LT+ G K + N Sbjct: 589 TKTKSGGNDGHTAVAVPKNQAKLGAEWDTQVAQGTLTLSGNINAVSKQYINAENT----- 643 Query: 753 EKFSQEDYWLVDLMARY--QITDK-LSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMF 809 S L+D+ ARY ++ D ++ N+ N+ +K Y+ T+ + G PR M Sbjct: 644 --LSVPGRTLLDVGARYSTKVEDHPVTFRANIYNLTNKAYWAQPQL-TNLALGAPRTYML 700 Query: 810 STRWDF 815 S +DF Sbjct: 701 SVSYDF 706 >4EPA-A nrPDB Length = 655 Score = 58.5 bits (140), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 40/141 (28%), Positives = 70/141 (49%), Gaps = 8/141 (5%) Query: 168 SITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYA----RGFS-INNFQYDGI 222 S TVV+ + D G+ D + R PG+ + + N ++ RG S +F + Sbjct: 32 SSTVVSAPELSDAGVTASDKLPRVLPGLNI---ENSGNMLFSTISLRGVSSAQDFYNPAV 88 Query: 223 PSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVE 282 V + NT+ + VE+L+G G L G + G IN++ ++P +G++E Sbjct: 89 TLYVDGVPQLSTNTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDSTPRGYIE 148 Query: 283 LGAGSWDNYRSELDVSGPLTE 303 G S D+YRS+ ++SGP+ + Sbjct: 149 GGVSSRDSYRSKFNLSGPIQD 169 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Query: 754 KFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTY----YTNIGFYTSASYGDPRNLMF 809 + Q Y +D +Q T++++ SV V+N+FD+ Y Y N G A R + Sbjct: 590 QLRQGTYATLDSSLGWQATERMNISVYVDNLFDRRYRTYGYMN-GSSAVAQVNMGRTVGI 648 Query: 810 STRWDF 815 +TR DF Sbjct: 649 NTRIDF 654 >2HDF-A nrPDB Length = 639 Score = 58.2 bits (139), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 79/163 (48%), Gaps = 11/163 (6%) Query: 152 IATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARG 211 + TA+ + ++ P SI+V+T++++ + N+ DV++ PG+ ++ +R RG Sbjct: 10 VVTASSVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRG 69 Query: 212 F--SINNFQYDGIPSTARNVGYSAGN-TLSDMAI--YDRVEVLKGATGLLTGAGSLGATI 266 S DG +RN + + L+ + + +R+EV++G L G+ +LG + Sbjct: 70 LDSSYTLILVDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVV 129 Query: 267 NLIRKKPTHEFKGHVELGA------GSWDNYRSELDVSGPLTE 303 N+I KK ++ G V + D Y + SGPL + Sbjct: 130 NIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLID 172 >3CSL-A nrPDB Length = 865 Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 69/285 (24%), Positives = 118/285 (41%), Gaps = 32/285 (11%) Query: 48 FDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTGASVD 107 F+I Q L SA+ F QA +QV + ++ +++A+ G + Q + L+ G + Sbjct: 16 FNIAAQPLQSAMLRFAEQAGMQVFFDEVKLDGMQAAALNGSMSVEQGLRRLIGGNPVAFR 75 Query: 108 FQGNAITISVAEAADSSVDLGATMITS-NQLGTITEDSGSYTPGTIATATRLVLTPRETP 166 Q I ++ ++ D GA + S LG ++ + + P Sbjct: 76 LQPQG-QIVLSRLPTANGDGGALALDSLTVLGAGGNNANDWV--------------YDEP 120 Query: 167 QSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDR----NNYYARGFSINNFQYDGI 222 +S++V++R+ MD+ + D++ T G S D N + + N DG+ Sbjct: 121 RSVSVISREQMDNRPARHAADILEQTTGAYSSVSQQDPALSVNIRGIQDYGRVNMNIDGM 180 Query: 223 PSTARNVGYSA--GNTLSDMAIYDRVEVLKGATGLLTGAGSLG--ATINLIRKK----PT 274 + G+ G D + V + KG TG + AG+LG AT N + P Sbjct: 181 RQNFQKSGHGQRNGTMYIDSELLSGVTIDKGTTGGMGSAGTLGGIATFNTVSASDFLAPG 240 Query: 275 HEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKH 319 E G +L A + DN + SG L GN G + A ++H Sbjct: 241 KELGG--KLHASTGDN-GTHFIGSGILA-LGNETGDILLAASERH 281 >1NQH-A nrPDB Length = 594 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 48/181 (26%), Positives = 82/181 (45%), Gaps = 13/181 (7%) Query: 148 TPGTIATATRLVLTPRETPQS-ITVVTRQNMDDFGLNNIDDVMRHTPG--ITVSAYDTDR 204 +P T+ PR T + TVVTRQ++D + +++DV+R PG IT + Sbjct: 4 SPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQL 63 Query: 205 NNYYARGFSINNFQY--DGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSL 262 ++ + RG + ++ DG+ V SA + +A+ RVE ++G + G+ ++ Sbjct: 64 SSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAI 123 Query: 263 GATINLI--RKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHS 320 G +N+I R +P E G+ S+ NY DVS R + Y H Sbjct: 124 GGVVNIITTRDEPGTEIS--AGWGSNSYQNY----DVSTQQQLGDKTRVTLLGDYAHTHG 177 Query: 321 F 321 + Sbjct: 178 Y 178 >5FR8-A nrPDB Length = 733 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 51/178 (28%), Positives = 80/178 (44%), Gaps = 27/178 (15%) Query: 152 IATATRLVLTPRETPQS--ITVVTRQNMDDFGL-NNIDDVMRHTPGITV---SAYDTDRN 205 + T V + QS ++V+T+++++ + N+I D +R PG+ + SA N Sbjct: 22 VKLETIFVTAEEQVKQSLGVSVITKEDLEKLPVRNDISDYVRRMPGVNLTGNSATGQRGN 81 Query: 206 NYYA--RGFSINN--FQYDGIPSTARN-VGYS---------AGNTLSDMAIYDRVEVLKG 251 N RG N DG P +RN V Y N + AI + +EVL+G Sbjct: 82 NRQIDIRGMGPENTLILVDGKPINSRNSVRYGWKGERDTRGDSNWVPAEAI-ESIEVLRG 140 Query: 252 ATGLLTGAGSLGATINLIRKKPTHEFKGHVEL------GAGSWDNYRSELDVSGPLTE 303 G+G+ G +N+I KK T+E G VE + + R +VSGPL + Sbjct: 141 PAAARYGSGAAGGVVNIITKKVTNETHGSVEFYTSQPEDSKEGSSNRVGFNVSGPLIK 198 >3FHH-A nrPDB Length = 640 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 11/121 (9%) Query: 153 ATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITV------SAYDTDRNN 206 TAT + E P ++V+ ++ + D++RH PGIT+ + D + Sbjct: 6 VTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQDINMRG 65 Query: 207 YYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATI 266 Y RG + DGI + G+ G T D A+ RVE+++G + LL G+G+LG I Sbjct: 66 YDHRGVLV---LVDGI-RQGTDTGHLNG-TFLDPALIKRVEIVRGPSALLYGSGALGGVI 120 Query: 267 N 267 + Sbjct: 121 S 121 >5FP2-A nrPDB Length = 725 Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 42/158 (26%), Positives = 71/158 (44%), Gaps = 22/158 (13%) Query: 182 LNNIDDVMRHTPGITVSAYDT--DRNNYYA---RGFSINN--FQYDGIPSTARN-VGYS- 232 +N++ +++R PG+ ++ + R N RG N DG P ++RN V Y Sbjct: 54 VNDLSEIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGW 113 Query: 233 --AGNTLSDM-----AIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL-- 283 +T D +R+EVL+G G+G+ G +N+I K+PT +G + + Sbjct: 114 RGERDTRGDSNWVPPEEVERIEVLRGPAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFT 173 Query: 284 ----GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQD 317 + R+ +SGPLTE+ + R A D Sbjct: 174 NIPESSKDGATRRANFSLSGPLTEALSFRAYGSANKTD 211 >5M9B-A nrPDB Length = 724 Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 85/230 (36%), Gaps = 25/230 (10%) Query: 576 VYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAY 635 +Y LN Y +Y+ + S Y N L+ + N E+GI EY L L Y Sbjct: 471 LYQLNPDYLLYSRGQGCYGQSTSCYL-RGNDGLKAETSVNKELGI--EYSHDGLVAGLTY 527 Query: 636 FEIHEENRAEEDALYNSKPTNPAITYAYKGI-------KAKTKGYEAEISGELAPGWQVQ 688 F +N+ E + YA I KA +G E ++ LA G + Sbjct: 528 FRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTLTLPLADGLKWS 587 Query: 689 AGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALD-----KLTVGGGARWQGKSWQM 743 T+ + + E D LS+ Y LD L++ W GK Sbjct: 588 NNLTYMLQSKNK-------ETGDVLSVTPRYTLNSMLDWQATDDLSLQATVTWYGKQKPK 640 Query: 744 VYNNPRSRWEKFSQED---YWLVDLMARYQITDKLSASVNVNNVFDKTYY 790 Y+ R + + Y + L Y+++ LS V+N+FDK + Sbjct: 641 KYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLF 690 Score = 33.9 bits (76), Expect = 0.26, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 67/150 (44%), Gaps = 34/150 (22%) Query: 183 NNIDDVMRHTPGITVSAYDT--DRNNYYA---RGFSINN--FQYDGIPSTARN-VGY--- 231 N++ ++R PG+ ++ + R N RG N DG P ++RN V Y Sbjct: 48 NDLSQIIRTMPGVNLTGNSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWR 107 Query: 232 ----SAGNT---LSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELG 284 S G+T +D +R+EV++G G G+ G +N+I K+ E G++ + Sbjct: 108 GERDSRGDTNWVPADQV--ERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSV- 164 Query: 285 AGSWDNY----------RSELDVSGPLTES 304 + N+ R ++GPLTE+ Sbjct: 165 ---YSNFPQHKAEGASERMSFGLNGPLTEN 191 >2M5J-A nrPDB Length = 107 Score = 38.1 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 34/67 (50%) Query: 43 AQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGT 102 AQ+ F+I Q L SA+ F QA +QV + ++ +++A+ G + Q + L+ G Sbjct: 6 AQQKNFNIAAQPLQSAMLRFAEQAGMQVFFDEVKLDGMQAAALNGSMSVEQGLRRLIGGN 65 Query: 103 GASVDFQ 109 + Q Sbjct: 66 PVAFRLQ 72 >1FEP-A nrPDB Length = 724 Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust. Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 36/154 (23%) Query: 184 NIDDVMRHTPGITVSAYDT--DRNNYYA---RGFSINN--FQYDGIPSTARNV---GYSA 233 ++ ++R PG+ ++ T R N RG N DG P ++RN G+ Sbjct: 44 DVSKIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRG 103 Query: 234 G-NTLSDMA-----IYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGS 287 +T D + + +R+EVL+G G G+ G +N+I KK + E+ GS Sbjct: 104 ERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWH-------GS 156 Query: 288 WDNY-------------RSELDVSGPLTESGNVR 308 WD Y R+ ++GPL + + R Sbjct: 157 WDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFR 190 Score = 28.9 bits (63), Expect = 8.5, Method: Compositional matrix adjust. Identities = 49/230 (21%), Positives = 88/230 (38%), Gaps = 35/230 (15%) Query: 575 AVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLA 634 ++Y N Y +Y+ + Y N L+ + N EIG++ + DG L + Sbjct: 470 SLYQTNPNYILYSKGQGCYASAGGCYL-QGNDDLKAETSINKEIGLEFKR-DGWL-AGVT 526 Query: 635 YFEIHEENRAEEDALYNSKPTNPAITYAYKGI-KAKTKGYEAEISGELAPG--WQVQAGY 691 +F N+ E + + Y + + KA +G E ++ ++ W Y Sbjct: 527 WFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITY 586 Query: 692 THKIIRDDSGKKVS-----------TWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKS 740 K +G ++S +W+ ++ LS+ T++ W GK Sbjct: 587 MLKSENKTTGDRLSIIPEYTLNSTLSWQAREDLSMQTTFT---------------WYGKQ 631 Query: 741 WQMVYN---NPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDK 787 YN P E Y +V L A + +T +S + V+N+FDK Sbjct: 632 QPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDK 681 >4AD7-A nrPDB Length = 528 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 54/150 (36%), Gaps = 7/150 (4%) Query: 117 VAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQN 176 +AEA ++ D T+ G PG R L PRE P S T+ + Sbjct: 320 LAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRRGKLAPRERPPSGTLEKLVS 379 Query: 177 MDDFGLNNIDDVMRHTPG------ITVSAYDTDRN-NYYARGFSINNFQYDGIPSTARNV 229 L ++ D PG + +S DR N ARG + DG+ + N Sbjct: 380 EAKAQLRDVQDFWISLPGTLCSEKMALSTASDDRCWNGMARGRYLPEVMGDGLANQINNP 439 Query: 230 GYSAGNTLSDMAIYDRVEVLKGATGLLTGA 259 T DM I ++ LK T L A Sbjct: 440 EVEVDITKPDMTIRQQIMQLKIMTNRLRSA 469 >6D6Q-B nrPDB Length = 249 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 30/58 (51%), Gaps = 5/58 (8%) Query: 38 AGYVQAQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAI 95 AG ++ + + QA GSA E G + V+Y P E+R R+ A+ P++A+ Sbjct: 23 AGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARAL-----PDRAL 75 >1PXT-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 16/94 (17%) Query: 509 DIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGR 568 D G G SQ D + + AR +V + LNL + GR +D++ G+ P I G Sbjct: 237 DRGTTTAGNASQVSDG----VAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 292 Query: 569 --FIPYVGA----------VYDLNDTYSVYASYT 590 IP V ++++N+ ++ A Y Sbjct: 293 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYC 326 >4HCX-A nrPDB Length = 409 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 434 WPAPDNSAKIVAQKYTGETKSNSLDIY---LTGPFQFLGR--EHELVVGTSASFSHWEGK 488 WP ++ + + Y G K +Y F+ G EH L+ A+ WEG Sbjct: 208 WPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGLTYEHRLIDDMVAACLKWEGG 267 Query: 489 SYWNLRNYD 497 W +NYD Sbjct: 268 YVWACKNYD 276 >4B7O-A nrPDB Length = 745 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 51/227 (22%), Positives = 94/227 (41%), Gaps = 34/227 (14%) Query: 609 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYN--SKPTNPAITYAYKGI 666 + + +N EIG Y DG + +YF + +DAL N ++ + A+ A Sbjct: 533 KAERARNTEIGF--NYNDGTFAANGSYFW-----QTIKDALANPQNRHVSAAVREAVNAG 585 Query: 667 KAKTKGYEAEISGELAPGWQVQAGYTHKIIR--DDSGKKVSTWEPQ------DQLSLYTS 718 K GYE S G + G +H R D KK+ + P+ + + Sbjct: 586 YIKNHGYELGASYRTG-GLTAKVGVSHSKPRFYDTHPKKLLSANPEFGAQVGRAWTASLA 644 Query: 719 YKFKGALDKLTVGGGARWQGKSWQMVY--------NNPRSRWEKFSQEDYWLVDLMARYQ 770 Y+F+ L +G W+G+ Q + + E ++ + + D+ A ++ Sbjct: 645 YRFQNP--NLEIG----WRGRYVQKAVGSILVAGQKDRNGKLENVVRKGFGVNDVFANWK 698 Query: 771 I--TDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 D L+ +++VNNVF+ YY + +T+ G R++ + F Sbjct: 699 PLGKDTLNVNLSVNNVFNTFYYPHSQRWTNTLPGVGRDVRLGVNYKF 745 >4AIP-A nrPDB Length = 742 Score = 29.6 bits (65), Expect = 5.0, Method: Compositional matrix adjust. Identities = 48/222 (21%), Positives = 92/222 (41%), Gaps = 24/222 (10%) Query: 609 EPDEGQNYEIGIKGEYLDGRLNTSLAYF-EIHEENRAEEDALYNSKPTNPAITYAYKGIK 667 + + +N EIG Y DG + +YF + ++ A ++S A+ Y Sbjct: 530 KAERARNTEIGF--NYNDGTFAANGSYFWQTIKDALANPQNRHDSVAVREAVNAGY---- 583 Query: 668 AKTKGYEAEISGELAPGWQVQAGYTHKIIR--DDSGKKVSTWEPQ------DQLSLYTSY 719 K GYE S G + G +H R D K+ + P+ + +Y Sbjct: 584 IKNHGYELGASYRTG-GLTAKVGVSHSKPRFYDTHKDKLLSANPEFGAQVGRTWTASLAY 642 Query: 720 KFKGALDKLTVGGGARWQGKSWQMVY----NNPRSRWEKFSQEDYWLVDLMARYQI--TD 773 +F+ L +G R+ K+ + + + E ++ + + D+ A ++ D Sbjct: 643 RFQNP--NLEIGWRGRYVQKATGSILAAGQKDRKGNLENVVRKGFGVNDVFANWKPLGKD 700 Query: 774 KLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 L+ +++VNNVF+K YY + +T+ G R++ + F Sbjct: 701 TLNVNLSVNNVFNKFYYPHSQRWTNTLPGVGRDVRLGVNYKF 742 >4W8Y-A nrPDB Length = 888 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 3/37 (8%) Query: 654 PTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAG 690 P + A+ AYK K K +E +G L PGW++ AG Sbjct: 697 PVDKALEVAYKIRKEFGKSFE---NGSLLPGWKLSAG 730 >2Z7X-A nrPDB Length = 549 Score = 29.3 bits (64), Expect = 7.1, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 22/42 (52%) Query: 105 SVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGS 146 S+D N IT V+L A ++TSN + TI EDS S Sbjct: 30 SLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFS 71 >5EIX-A nrPDB Length = 741 Score = 29.3 bits (64), Expect = 7.5, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 20/40 (50%) Query: 423 YHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLT 462 Y PLG G+W APD+ A +YT S ++ L+ Sbjct: 340 YRYPLGDGQGNWGAPDDPKSFAAMRYTESRLSKYAELLLS 379 >3GDB-A nrPDB Length = 937 Score = 28.9 bits (63), Expect = 9.2, Method: Compositional matrix adjust. Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 13/84 (15%) Query: 511 GKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVV-----DYR-VTGLNPTIR 564 G DW + + D+T +G+ T FN F+ G+V +YR V+G+ PT R Sbjct: 491 GDKDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR 550 Query: 565 ----ESGRFIPYVGAVYDLNDTYS 584 +G + A YD D Y+ Sbjct: 551 WWQTSTGEKLR---AEYDFTDAYN 571 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2W78-A nrPDB 992 0.0 1XKH-A nrPDB 867 0.0 3EFM-A nrPDB 710 0.0 1XKW-A nrPDB 658 0.0 6E4V-A nrPDB 637 0.0 1FCP-A nrPDB 559 e-159 5FP1-A nrPDB 500 e-142 3QLB-A nrPDB 490 e-139 6H7F-A nrPDB 477 e-135 5NEC-A nrPDB 414 e-116 5FOK-A nrPDB 413 e-115 6BPM-C nrPDB 371 e-103 3CSL-A nrPDB 275 4e-74 2HDF-A nrPDB 207 2e-53 1NQH-A nrPDB 189 5e-48 5FP2-A nrPDB 182 6e-46 4EPA-A nrPDB 181 1e-45 5FR8-A nrPDB 165 5e-41 3FHH-A nrPDB 150 2e-36 2A02-A nrPDB 117 3e-26 Sequences not found previously or not previously below threshold: 1KMO-A nrPDB 190 2e-48 5M9B-A nrPDB 180 2e-45 1FEP-A nrPDB 163 2e-40 2M5J-A nrPDB 130 3e-30 6FOK-A nrPDB 113 5e-25 4AIP-A nrPDB 110 3e-24 4B7O-A nrPDB 108 1e-23 3V8X-A nrPDB 66 5e-11 4RDT-A nrPDB 63 5e-10 2D1U-A nrPDB 49 1e-05 1ZZV-A nrPDB 44 3e-04 5FQ8-B nrPDB 43 8e-04 4ZGV-A nrPDB 41 0.002 5D0Q-A nrPDB 38 0.019 3RQ4-A nrPDB 34 0.22 4AU7-A nrPDB 34 0.26 3SQR-A nrPDB 33 0.55 3ZTV-A nrPDB 33 0.66 4G2C-A nrPDB 32 0.90 1W3H-A nrPDB 32 0.92 6D6Q-B nrPDB 32 1.0 6FSU-A nrPDB 32 1.1 5EW5-A nrPDB 31 1.9 3AK5-A nrPDB 30 3.5 >2W78-A nrPDB Length = 772 Score = 992 bits (2563), Expect = 0.0, Method: Composition-based stats. Identities = 772/772 (100%), Positives = 772/772 (100%) Query: 44 QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTG 103 QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTG Sbjct: 1 QEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTG 60 Query: 104 ASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPR 163 ASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPR Sbjct: 61 ASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPR 120 Query: 164 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIP 223 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIP Sbjct: 121 ETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIP 180 Query: 224 STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL 283 STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL Sbjct: 181 STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL 240 Query: 284 GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPD 343 GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPD Sbjct: 241 GAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPD 300 Query: 344 TMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLE 403 TMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLE Sbjct: 301 TMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLE 360 Query: 404 HNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTG 463 HNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTG Sbjct: 361 HNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTG 420 Query: 464 PFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYID 523 PFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYID Sbjct: 421 PFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYID 480 Query: 524 DKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY 583 DKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY Sbjct: 481 DKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY 540 Query: 584 SVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENR 643 SVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENR Sbjct: 541 SVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENR 600 Query: 644 AEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKK 703 AEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKK Sbjct: 601 AEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKK 660 Query: 704 VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLV 763 VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLV Sbjct: 661 VSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLV 720 Query: 764 DLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 DLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF Sbjct: 721 DLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 772 >1XKH-A nrPDB Length = 687 Score = 867 bits (2239), Expect = 0.0, Method: Composition-based stats. Identities = 687/687 (100%), Positives = 687/687 (100%) Query: 129 ATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDV 188 ATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDV Sbjct: 1 ATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDV 60 Query: 189 MRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEV 248 MRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEV Sbjct: 61 MRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEV 120 Query: 249 LKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVR 308 LKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVR Sbjct: 121 LKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVR 180 Query: 309 GRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPL 368 GRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPL Sbjct: 181 GRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPL 240 Query: 369 FDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLG 428 FDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLG Sbjct: 241 FDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLG 300 Query: 429 AIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK 488 AIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK Sbjct: 301 AIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGK 360 Query: 489 SYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLG 548 SYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLG Sbjct: 361 SYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLG 420 Query: 549 GRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLL 608 GRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLL Sbjct: 421 GRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLL 480 Query: 609 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKA 668 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKA Sbjct: 481 EPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKA 540 Query: 669 KTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKL 728 KTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKL Sbjct: 541 KTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKL 600 Query: 729 TVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT 788 TVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT Sbjct: 601 TVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT 660 Query: 789 YYTNIGFYTSASYGDPRNLMFSTRWDF 815 YYTNIGFYTSASYGDPRNLMFSTRWDF Sbjct: 661 YYTNIGFYTSASYGDPRNLMFSTRWDF 687 >3EFM-A nrPDB Length = 707 Score = 710 bits (1832), Expect = 0.0, Method: Composition-based stats. Identities = 269/717 (37%), Positives = 401/717 (55%), Gaps = 31/717 (4%) Query: 118 AEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNM 177 A + L A +T ++ +TE + +YT ++TAT L L+PRETPQS++VVTRQ + Sbjct: 3 ARTGNDIAQLPAISVTGREISDLTEGTNAYTTEAMSTATGLTLSPRETPQSVSVVTRQQI 62 Query: 178 DDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTL 237 +D GL + ++ PGI+V+ D++R ++ ARGF+I+NFQ+DG+ S ++ G+T Sbjct: 63 EDQGLTDTGAILATAPGISVTRSDSNRYSFSARGFTIDNFQFDGLVSPIL-SQWNYGSTD 121 Query: 238 SDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDV 297 D AIYD VE+++GATGL+TG+G+ A +N +RK+P EF GSWD R + D+ Sbjct: 122 MDAAIYDHVEIVRGATGLMTGSGNPSAAVNFVRKRPLREFAATFNASVGSWDYVRGDADI 181 Query: 298 SGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDP 357 S P+TE G +R R VAAY S++ + + +YG++ DL PDT+LT +YQ N Sbjct: 182 SVPITEDGRIRSRLVAAYSQGDSYVHFLDTRRRTFYGVVSADLTPDTVLTTSVEYQHNHS 241 Query: 358 KGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLD 417 G G FPLF S G+R D +RS N A W+ + T F +L H F N W + Sbjct: 242 NGFG--SGFPLFYSDGSRTDFNRSVANNAPWARQDTEATTYFVDLTHRFTNDWKLRAAYS 299 Query: 418 HKINGYHAPLGAIMGDWPAPDNSAKIVA-----QKYTGETKSNSLDIYLTGPFQFLGREH 472 H +G + G + PD I+A Y G + + L+ PF+ G H Sbjct: 300 H-TDGRYLMKHVYRGGY--PDRHTGIIAAPPAFSNYDGNLDRDDIHFSLSAPFEAFGLRH 356 Query: 473 ELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINW---------DGDIGKPDWG-TPSQYI 522 E+ +G + +H + + + + F +W I +P W T S Sbjct: 357 EVALGWMSIDNHSDIQR-YAMVGPAPAIGSFFDWRRAGSHHHHHHHIQEPSWADTLSPAD 415 Query: 523 DDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVT----GLNPTIRESGRFIPYVGAVYD 578 D +T+Q G+Y+ RF + + L+L +G R D++ G R +F PY G YD Sbjct: 416 DVRTKQTGAYLVGRFALAEPLHLIVGDRWSDWKTKQMYFGSRREYRIKNQFTPYAGLTYD 475 Query: 579 LNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEI 638 +NDTY+ YASYT+IF PQ++ RD+S +L P + ++YE+G+K YL+GRLNTS A F+ Sbjct: 476 INDTYTAYASYTEIFQPQNA--RDTSGGILPPIKSKSYELGLKAAYLEGRLNTSAALFQT 533 Query: 639 HEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRD 698 ++N A+ +S P P + + AK +G + E SG++ P W + A YTH +D Sbjct: 534 RQDNLAQVIP-GSSIPGFPNMQASRAASGAKVEGIDLEASGQILPDWNIGASYTHFTTKD 592 Query: 699 DSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQE 758 SG ++T P+ LYT+Y+ GAL +LTVGGG WQ + +Q +PR E Q+ Sbjct: 593 ASGNPINTNHPRSLFKLYTTYRLPGALHRLTVGGGVDWQSRMYQ-AAASPRGNVE-VEQD 650 Query: 759 DYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 Y LV LMAR+ KLSA++NVNN+FDK YY IGFY+ +G PRN+M + R + Sbjct: 651 SYALVSLMARFDFNKKLSATLNVNNLFDKKYYDQIGFYSQGWWGAPRNVMLNLRAQY 707 >1XKW-A nrPDB Length = 665 Score = 658 bits (1697), Expect = 0.0, Method: Composition-based stats. Identities = 239/686 (34%), Positives = 358/686 (52%), Gaps = 33/686 (4%) Query: 142 EDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYD 201 E + + P + T ++ L PRE PQS +V+ + ++ L ++D+ M+ G+TV + Sbjct: 1 ESTSATQPPGVTTLGKVPLKPRELPQSASVIDHERLEQQNLFSLDEAMQQATGVTVQPFQ 60 Query: 202 TDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGS 261 YY RGF +++F+ DG+P+ N S DMAIY+RVE+L+G+ GLL G G+ Sbjct: 61 LLTTAYYVRGFKVDSFELDGVPALLGNTASSP----QDMAIYERVEILRGSNGLLHGTGN 116 Query: 262 LGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSF 321 AT+NL+RK+P EF L AG WD YR+E+DV GPL+ SGNVRGRAVAAY+D+ F Sbjct: 117 PAATVNLVRKRPQREFAASTTLSAGRWDRYRAEVDVGGPLSASGNVRGRAVAAYEDRDYF 176 Query: 322 MDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRS 381 D ++ T + YG+ EFDL+PDT+LTVGA YQ D + P+ G+ +SR Sbjct: 177 YDVADQGTRLLYGVTEFDLSPDTLLTVGAQYQHIDSITN--MAGVPM-AKDGSNLGLSRD 233 Query: 382 FNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKING----YHAPLGAIMGDWPAP 437 W ++ T F +LE GW GKV +++ Y GAI P Sbjct: 234 TYLDVDWDRFKWDTYRAFGSLEQQLGGGWKGKVSAEYQEADSRLRYAGSFGAID---PQT 290 Query: 438 DNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYD 497 + +++ Y ++ SLD L GP + G HEL+ G + + + N Sbjct: 291 GDGGQLMGAAYKFKSIQRSLDANLNGPVRLFGLTHELLGGVTYAQGETRQDTA-RFLNLP 349 Query: 498 NTTDDFINWDGD-IGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRV 556 NT + WD + +P G + T Q G Y R + + L L +GGR + Sbjct: 350 NTPVNVYRWDPHGVPRPQIGQYTSPGTTTTTQKGLYALGRIKLAEPLTLVVGGRESWWDQ 409 Query: 557 TGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNY 616 + +F PY G ++D +S Y SY +++ PQ + +++ L P EG+ Y Sbjct: 410 DTPATRFKPGRQFTPYGGLIWDFARDWSWYVSYAEVYQPQAD-RQTWNSEPLSPVEGKTY 468 Query: 617 EIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAE 676 E GIKGE DGRLN SLA F I EN +ED + P NP + G K +++G+E E Sbjct: 469 ETGIKGELADGRLNLSLAAFRIDLENNPQEDPDHPGPPNNP---FYISGGKVRSQGFELE 525 Query: 677 ISGELAPGWQVQAGYTH------KIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTV 730 +G L P W + AGYT+ K ++DSG + ST+ P+ L L+++Y + +V Sbjct: 526 GTGYLTPYWSLSAGYTYTSTEYLKDSQNDSGTRYSTFTPRHLLRLWSNYDLPWQDRRWSV 585 Query: 731 GGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYY 790 GGG + Q + + Y R Q Y LV++ Y+I + +A+VNVNN+FD+TYY Sbjct: 586 GGGLQAQ-SDYSVDY-----RGVSMRQGGYALVNMRLGYKIDEHWTAAVNVNNLFDRTYY 639 Query: 791 TNIGFYT-SASYGDPRNLMFSTRWDF 815 ++ + YG+PR+ S R F Sbjct: 640 QSLSNPNWNNRYGEPRSFNVSLRGAF 665 >6E4V-A nrPDB Length = 693 Score = 637 bits (1642), Expect = 0.0, Method: Composition-based stats. Identities = 248/707 (35%), Positives = 374/707 (52%), Gaps = 34/707 (4%) Query: 128 GATMITSNQLGTITEDS---GSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNN 184 AT T G+ T Y+ + + T++ +T R+ PQS+T+V++Q M+D L Sbjct: 2 PATEETVIVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQT 61 Query: 185 IDDVMRHTPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYD 244 + +VM +T GI+ S D+DR YY+RGF I+N+ DGIP+ ++ G+ LSDMA+++ Sbjct: 62 LGEVMENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYF-ESRWNLGDALSDMALFE 120 Query: 245 RVEVLKGATGLLTGAGSLGATINLIRKKPT-HEFKGHVELGAGSWDNYRSELDVSGPLTE 303 RVEV++GATGL+TG G+ A IN++RK T EFKG V GSW+ R D+ PLTE Sbjct: 121 RVEVVRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTE 180 Query: 304 SGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWS 363 G +R R V YQ+ S++D Y + + + GI++ DL T L+ G +YQ D W Sbjct: 181 DGKIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTW- 239 Query: 364 GSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVG-------KVQL 416 G P +++ G+ N R+ + W+ ++ VF L+ FA+ W +V+ Sbjct: 240 GGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNATHSEVEF 299 Query: 417 DHKINGYHAPL----GAIMGDWPAPDNSAKIVAQK--YTGETKSNSLDIYLTGPFQFLGR 470 D K+ A + G ++G + V +G+ K ++LD++ G ++ GR Sbjct: 300 DSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGR 359 Query: 471 EHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLG 530 +H L+ G S S + S W + + F N++G+ + DW S DD T Sbjct: 360 QHNLMFGGSYSKQNNRYFSSWANI-FPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKS 418 Query: 531 SYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYT 590 Y R + D L+L LG R ++RV L ++ E PY G V+D+ND +S YASYT Sbjct: 419 LYAATRVTLADPLHLILGARYTNWRVDTLTYSM-EKNHTTPYAGLVFDINDNWSTYASYT 477 Query: 591 DIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALY 650 IF PQ+ RDSS K L P G NYE+G+K ++++ RL T+LA F I ++N A+ Sbjct: 478 SIFQPQND--RDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQST--G 533 Query: 651 NSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQ 710 P + T +KG E E++G + WQ+ G T I D+ G V+ P+ Sbjct: 534 TPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPR 593 Query: 711 DQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFS--QEDYWLVDLMAR 768 + ++TSY+ + +LTVGGG WQ + VY + + + F Q Y LVDL R Sbjct: 594 TTVKMFTSYRLP-VMPELTVGGGVNWQNR----VYTDTVTPYGTFRAEQGSYALVDLFTR 648 Query: 769 YQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 YQ+T S NVNN+FDKTY TN+ S YG PRN + + F Sbjct: 649 YQVTKNFSLQGNVNNLFDKTYDTNVE--GSIVYGTPRNFSITGTYQF 693 >1FCP-A nrPDB Length = 705 Score = 559 bits (1441), Expect = e-159, Method: Composition-based stats. Identities = 157/724 (21%), Positives = 289/724 (39%), Gaps = 67/724 (9%) Query: 139 TITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVS 198 + + + AT T+ ++ PQSI+VVT + M ++ + + +TPG++V Sbjct: 2 SAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEALSYTPGVSVG 61 Query: 199 AYDTDR--NNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLL 256 ++ RGF+ + + + G + + D + +R E+++G +L Sbjct: 62 TRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLERAEIMRGPVSVL 121 Query: 257 TGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQ 316 G S G +N++ K+PT E V+ AG+ +++ D S L + G R + Sbjct: 122 YGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLDDDGVYSYRLTGLAR 181 Query: 317 DKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFP---LFDSQG 373 ++ E + + + T T + +Q + +G+ G P + Sbjct: 182 SANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQ--NEPETGYYGWLPKEGTVEPLP 239 Query: 374 NRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQL--------DHKINGYHA 425 N + FN GAK +++ + + V + +H F + + + L + + GY Sbjct: 240 NGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLRFAENKTSQNSVYGYGV 299 Query: 426 ---PLGAIMGDWP--APDNSAKIVAQKYT---GETKSNSLDIYLTGPFQFLGREHELVVG 477 P A AP + +A+KY + ++ S+D L F +H L+ G Sbjct: 300 CSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQSKFATGDIDHTLLTG 359 Query: 478 T---------SASFSHWEGKSYWNLRNYDNTTDD--FINWDGDIGKPDWGTPSQY-IDDK 525 +A F + + NL N + +N D D D Y I +K Sbjct: 360 VDFMRMRNDINAWFGYDDSVPLLNLYNPSHHHHHHGSVNTDFDFNAKDPANSGPYRILNK 419 Query: 526 TRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTI-----RESGRFIPYVGAVYDLN 580 +Q G Y+ + D + + LGGR LN R+ +F G Y + Sbjct: 420 QKQTGVYVQDQAQW-DKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQFTWRGGVNYLFD 478 Query: 581 DTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHE 640 + + Y SY++ F P +D + + P +G+ YE+G+K D + + A + + + Sbjct: 479 NGVTPYFSYSESFEPSSQVGKDGN--IFAPSKGKQYEVGVKYVPEDRPIVVTGAVYNLTK 536 Query: 641 ENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTH---KIIR 697 N D ++ +G + + +G E E L+ V YT+ + Sbjct: 537 TNNLMADP--------EGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYTDAEYTT 588 Query: 698 DDSGKKVSTWE-PQDQLSLYTSYK-FKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKF 755 D + K + + P+ SL+ Y F G L LT+G G R+ G S+ N+ F Sbjct: 589 DTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS-------F 641 Query: 756 SQEDYWLVDLMARYQITDKLSASVN----VNNVFDKTYYTNIGFYTSASYGDPRNLMFST 811 Y +VD + RY + A N VNN+FD+ Y + +G R ++ + Sbjct: 642 KVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVVATA 701 Query: 812 RWDF 815 + F Sbjct: 702 TFRF 705 >5FP1-A nrPDB Length = 718 Score = 500 bits (1288), Expect = e-142, Method: Composition-based stats. Identities = 170/767 (22%), Positives = 300/767 (39%), Gaps = 126/767 (16%) Query: 122 DSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFG 181 ++ L + Q ++ D + ++ V +TP+S++V+++Q ++D Sbjct: 5 EAVSQLPTIHTKATQEESLKVDQSA--------NSKFVAPLLDTPKSVSVISKQLIEDTK 56 Query: 182 LNNIDDVMRHTPGITVSAYDT---DRNNYYARGFSINN-FQYDGIPSTARNVGYSAGNTL 237 + + D +R PGIT+ A + + + + RG+S + DGI ++ + Sbjct: 57 VTTLADALRTVPGITLGAGEGGNPNGDRPFIRGYSSESSMYIDGIR--------NSTSQN 108 Query: 238 SDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDV 297 +M ++VEV KG+ + GAGS+G +IN+I K + AG+ + R LD Sbjct: 109 REMFAVEQVEVTKGSASAMGGAGSVGGSINMISKVAKKGDFLEGSVAAGTDNYQRITLDG 168 Query: 298 SGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADY-QDND 356 + R + +K + E K + F L+ T T+ Y Q +D Sbjct: 169 NKDFGNGIAARVAVLGHQNEKAGQSNGAEYKRVGIAPSITFGLDTPTRATLSYYYLQTDD 228 Query: 357 PKGSG---WSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGK 413 SG W S L +QG +V + + W+ F E++ +G Sbjct: 229 KPDSGIPYWDSS--LGKAQGKPAEVKQG-----TYYGWKDRD---FQKQENH-----IGT 273 Query: 414 VQLDHKINGYHAPLGAIMGD-------WPAPDNSAKIVAQKYT--------GETKSNSLD 458 ++L+H + M W PD+S V + ++++ + Sbjct: 274 IKLEHDLTDNITITNTAMYAKSKNDYVWTNPDDSKGNVGKGLVWHRLNSAITDSETFTDQ 333 Query: 459 IYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRN----------YDNTTDDFINWDG 508 + LTG F +H VG S + K +N+ + Y + +D NW Sbjct: 334 LALTGKFDTGFLKHRFNVGAEYSKQKTD-KGGYNIIDAKGNVSSTGFYSDCSDLSTNWCT 392 Query: 509 DIGKP------DWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRV------ 556 + P D D Y+ +T L LG R + Sbjct: 393 SLNGPTQKPFVDRLQARPDFDATVESTSVYLLDNIEITPKWLLDLGLRWDKFEAEQNFLA 452 Query: 557 --TGLNPTIRESGRF-IPYVGAVYDLNDTYSVYASYTDIFMP--------QDSWYRDSSN 605 + T + + F G + + S+Y SY P +S +++N Sbjct: 453 TSSAAAYTAKNNSDFVTYQAGITFKPTENGSIYTSYATSASPVGLNAGWGDNSETINANN 512 Query: 606 KLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEEN-RAEEDALYNSKPTNPAITYAYK 664 ++++P+E Q +EIG K ++LD LN + A F ++N R + D TYA Sbjct: 513 QMIDPEEAQTFEIGTKWDFLDNHLNLTAAIFRTEKQNTRVQIDP----------TTYANV 562 Query: 665 GIKAKTKGYEAEISGELAPGWQVQAGYTH---------KIIRDDSGKKVS-------TWE 708 G ++K G+E ++GE+ W + AGYT+ K R S Sbjct: 563 G-ESKVDGFELGLNGEITDKWNISAGYTYLDSELTKNGKSCRSGKCTDQSIYNGNQMPNV 621 Query: 709 PQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMAR 768 P+ +L+T+YK L +LTVG GA + K + V N Y D MAR Sbjct: 622 PKQAATLWTTYK---VLPQLTVGAGAVYSDKVYGDVANTK-------WVPSYVRYDAMAR 671 Query: 769 YQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 Y + + +N+NN+ DK Y+T A+ + R+ + + + + Sbjct: 672 YNVNKNVDLQLNINNLSDKRYFTKAYASHYATEAEGRSAVLAVNFKY 718 >3QLB-A nrPDB Length = 748 Score = 490 bits (1262), Expect = e-139, Method: Composition-based stats. Identities = 159/756 (21%), Positives = 275/756 (36%), Gaps = 64/756 (8%) Query: 96 TELLRGTGASVDFQGNAITISVAEAA-----------DSSVDLGATMITSNQLGTITEDS 144 L + G A+ +S+ +A D ++ L ++I++ Q + T Sbjct: 21 RPALGRNPLACLIHGLALGLSLTQAGAALAADGDTDQDHALTLDTSVISATQPDSATGPQ 80 Query: 145 GSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGI--TVSAYDT 202 Y + T+ + E PQSI+V+TR MD + ++++ +R+T G+ +A Sbjct: 81 AGYVAKRSLSGTKTDASLSEIPQSISVITRDQMDAQQVQSVNEALRYTAGVQANTTAASQ 140 Query: 203 DRNNYYARGFSIN-NFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGS 261 + RGF + DG+ + +R++VLKG +L G S Sbjct: 141 RFDTLSIRGFDVTTGMLRDGLKGNTA-----QAWPKVEAYGLERIDVLKGPASVLFGQNS 195 Query: 262 LGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSF 321 G +N I K+P + V++ GS+D + + D SGPL + G R V +D + Sbjct: 196 PGGVVNQISKRPLDKPFHEVQIQGGSFDRAQGQFDFSGPLDDEGQFLYRLVGLERDSGTQ 255 Query: 322 MDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDS-QGNRND-VS 379 DH + + + N DT LT+ ADY + P + GN N V Sbjct: 256 FDHIKDDKQYFAPSFTWKPNDDTSLTLLADYTQDTFGAP--RVFLPAQGTLLGNPNGKVR 313 Query: 380 RSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPD- 438 + ++ ++ LEH + W + + + G APD Sbjct: 314 HNVFLDEPGLDNDRTQYSLGYLLEHRLNDVW--SLNSSARYGHVNLLTNTASGMSLAPDL 371 Query: 439 NSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDN 498 + A ++ + SLD + + ++G + + + + Sbjct: 372 RTLNRAAYRFRIVGDTYSLDNNAQARWNLGSTQMVSLLGIDYRRTREDYYLRGGSASPID 431 Query: 499 TTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTG 558 + + G D TP + Q+G Y +F + L +GGR D Sbjct: 432 IYNPVHHHHHHGGVFDPSTPFTNTVQRADQVGVYAQQQFTFDEHWVLTVGGR-QDRSSAR 490 Query: 559 LNPTIRESG------RFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDE 612 + + +SG +F G VY ++ + Y SY+ F P + +P Sbjct: 491 TDNRMNDSGSKQDDEKFTYRTGLVYLADNGLAPYISYSTSFDPV--LGTNFYGTPYKPTS 548 Query: 613 GQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKG 672 + E+G+K + +L+ F++ +EN D + +G Sbjct: 549 AKQSEVGVKYQPPGIDSYITLSLFDLTQENVLTTDPAQRLNKIQTG--------EINVRG 600 Query: 673 YEAEISGELAPGWQVQAGYTHKIIRDDSGK------KVSTWEPQDQLSLYTSYKFK-GAL 725 E E LA G + A T+ K T P+ SL+ Y G L Sbjct: 601 IELEGKASLARGLDLLAALTYNDAEVSKSNNPLEKGKRPTDTPEKMASLWADYTLPEGPL 660 Query: 726 DKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSA------SV 779 L G G R+ G + N R Y L+D Y + A +V Sbjct: 661 SGLGFGAGVRYIGSTEADAANTQR-------VPSYTLLDAAVHYDFDKLIPAAKGLRLAV 713 Query: 780 NVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 N N+ DK YY T+ S G R+++ S R+ + Sbjct: 714 NATNLTDKHYYEGCSL-TNCSAGYDRSVIASLRYRW 748 >6H7F-A nrPDB Length = 706 Score = 477 bits (1227), Expect = e-135, Method: Composition-based stats. Identities = 164/765 (21%), Positives = 290/765 (37%), Gaps = 111/765 (14%) Query: 103 GASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTP 162 GA + T+ A + L A + + E +Y G +AT++ + Sbjct: 1 GAMAVIDNSTKTLEQQTAQTNVAALPAITVKA-------EQDDTYAGGQVATSSNVGFLG 53 Query: 163 R----ETPQSITVVTRQNMDDFGLNNIDDVMRHT-PGI-TVSAYDTDRNNYYARGF--SI 214 +TP + T + ++D +I +V+ T P I T A NYY RG+ S Sbjct: 54 SKKFLDTPFNTISYTDKYIEDKQAKDITEVIAATDPSIYTNGASGGWSENYYIRGYASST 113 Query: 215 NNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTG---AGSLGATINLIRK 271 N+ +G+ G + S ++ RVEVLKG + LL G AGS+G T+NL+ K Sbjct: 114 NDMSMNGL------FGITPFYRTS-PEMFGRVEVLKGPSALLNGMPPAGSVGGTVNLVTK 166 Query: 272 KPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSV 331 E + S + +DV E+ R Y+D + ++ +++ + Sbjct: 167 YAADEPFARLTTTYMSDAQFGGHVDVGRRFGENKEFGVRINGMYRDGDAAVNDQSKESRL 226 Query: 332 YYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNN------- 384 + ++G D+Q G +D+ + + V+R N Sbjct: 227 F--------------SLGLDWQ-----GENARVFVDAYDALDHVDGVTRGVNVSTAVGIP 267 Query: 385 ---------GAKWSSWEQYTRTVFANLEHNFANGWV-----GKVQLDHKINGYHAPLGAI 430 W S E + E++F++ + G+ ++K NG A Sbjct: 268 KPPKADTLLSPDWGSVETKDKGAMIRGEYDFSDQLMAYAAYGQSTTEYKYNGASA----- 322 Query: 431 MGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSY 490 G + + + + S D G F+ +H+ V + ++H + Sbjct: 323 -GTITSSTGTLSSTLGQLAFDVDKKSADAGFKGKFETGSVKHQWVA-NATYYNHTQDD-- 378 Query: 491 WNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDD-------KTRQLGSYMTARFNVTDDL 543 + R +D I D P+WG ++ T G T F D + Sbjct: 379 YGYRIIPGFSDPVITNIYD-PNPNWGPKPEFTPPFLFHSTLSTSSFGLADTLSFA-QDKV 436 Query: 544 NLFLGGRVVDYRVTGLNPTIRESGR--FIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYR 601 L LG R + T T+ E+ + P V + D SVYA+Y + D Sbjct: 437 QLTLGLRHQTVKATSSVNTLPENAKSATTPGVALLIKATDKISVYANYIEGLTKGDQAPA 496 Query: 602 DSSN--KLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAI 659 +SN ++ P + + E+G+K + G +L+ FEI + + L SK N Sbjct: 497 TASNPGEIFPPQKTKQQELGLKVDL--GTFAHTLSAFEITKPS----SYLDPSKLVNNLP 550 Query: 660 TYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTH---KIIRDDSGKK---VSTWEPQDQL 713 T+ G + + +G E G ++ G+T+ ++ + SG + P++Q Sbjct: 551 TFVSDG-EQRNRGIEWSFFGSPIEHVRLMGGFTYLDPELTKTKSGGNDGHTAVAVPKNQA 609 Query: 714 SLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARY--QI 771 L + + A LT+ G K + N S L+D+ ARY ++ Sbjct: 610 KLGAEWDTQVAQGTLTLSGNINAVSKQYINAENT-------LSVPGRTLLDVGARYSTKV 662 Query: 772 TDK-LSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 D ++ N+ N+ +K Y+ T+ + G PR M S +DF Sbjct: 663 EDHPVTFRANIYNLTNKAYWAQPQL-TNLALGAPRTYMLSVSYDF 706 >5NEC-A nrPDB Length = 741 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 166/763 (21%), Positives = 268/763 (35%), Gaps = 111/763 (14%) Query: 122 DSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFG 181 D + L A I Q T + + + + +TP+S+TVV +Q + D Sbjct: 13 DRVLSLDAATIVGEQQDETTYNVDR------SASKKYTAPLLDTPRSVTVVPKQVIKDTA 66 Query: 182 LNNIDDVMRHTPGITVSAYDTDR---NNYYARGFSIN-NFQYDGIPSTARNVGYSAGNTL 237 ++ D +R PGIT A + + + RGF + DG+ T G Sbjct: 67 AVSLQDALRTVPGITFGAGEGGNPTGDRPFIRGFDAQSDTYVDGVRDT--------GAQT 118 Query: 238 SDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDV 297 ++ +++EV KG G GS G ++NL+ K+ GS R LD+ Sbjct: 119 REIFNLEQIEVSKGPNSAFGGRGSAGGSLNLVSKQAKAGNFIDGGFTYGSDQTRRYTLDL 178 Query: 298 SGPLTESGNVRGRAVAAYQDKH-SFMDHYERKTSVYYGILEFDLNPDTMLTVGADY-QDN 355 + + GN R D + + D + L F L T +TV + + + Sbjct: 179 NQEFLD-GNAAFRLNLLKHDANVAGRDEVDVSRWGVAPSLTFGLGSPTRVTVSHYHLESD 237 Query: 356 DPKGSG---WSGSFPLFDSQGNRNDVSRS-FNNGAKWSSWEQYTRTVFANLEHNFANGWV 411 D SG S + +V R F + T +EH+ + Sbjct: 238 DTPDSGIPYAKSSDRSKHNPDKPVNVDRGNFYGLTGRDFQKSRIDTSTITVEHDLTDSLT 297 Query: 412 GKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSL--------DIYLTG 463 + + W PD+S + ++N + L G Sbjct: 298 IRNTSRYG-------NSHQDYLWTQPDDSQGNINNGSVWRRQNNRVSTTTTAVNQTDLFG 350 Query: 464 PFQFLGREHELVVGTSASFSHWEGKSYW---------NLRNYDNTTDDFINWDGDIGKPD 514 F G ++ G S + Y N N + P+ Sbjct: 351 EFYLGGFKNSFSTGLEFSREDSKRDGYIVDTNTGLGSNKCNPSLIGAPSGYNCTSLENPN 410 Query: 515 WGTP--------SQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRES 566 P ++ Y ++ + + +G R + T N +R + Sbjct: 411 PHDPWNGSITRKYAPLNTVGTTKAIYAFDTIDLNEQWQVNIGARFDSFETTAKNHGVRPA 470 Query: 567 GRFI-------PYVGAVYDLNDTYSVYASYTDIFMPQDSWYR--DSSNKL--------LE 609 + G V+ S+YASY P S D+SN + LE Sbjct: 471 TKLSDKSSFWNWQAGLVWKPVPNGSIYASYATSATPPGSMLDNGDTSNAVDGFAISNNLE 530 Query: 610 PDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAK 669 P+E NYE+G K + + RL S A F ++N ++ TY G +++ Sbjct: 531 PEETTNYELGTKWAFFNERLELSAAIFRTDKDN---------TRILVANQTYDNAG-QSR 580 Query: 670 TKGYEAEISGELAPGWQVQAGYTHKIIR-DDSGKKVS----------------TWEPQDQ 712 G E SG+L W+V AGY++ D+GK P++ Sbjct: 581 VDGVELSASGKLTEKWKVFAGYSYLDSELVDAGKAGRNGNVNASAASNNGNEMPNTPKNS 640 Query: 713 LSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQIT 772 SL+T+Y K T+GGGA + K + V N DYW D MA Y+++ Sbjct: 641 FSLWTTYDI---FPKTTIGGGAFYVDKVYGDVGNT-------VYVPDYWRYDAMASYKLS 690 Query: 773 DKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 + +NV NVFDK Y+ AS R ++FST + F Sbjct: 691 KNVDFQLNVQNVFDKKYFDKAYAAHYASQAAGRTILFSTNFHF 733 >5FOK-A nrPDB Length = 730 Score = 413 bits (1062), Expect = e-115, Method: Composition-based stats. Identities = 150/752 (19%), Positives = 262/752 (34%), Gaps = 102/752 (13%) Query: 122 DSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFG 181 D + L A I Q T + + + + +TP+++TV+ +Q + D G Sbjct: 12 DRVLSLDAATIVGEQQDETTYNVDR------SASKKYTAPLLDTPKTVTVIPQQVIKDTG 65 Query: 182 LNNIDDVMRHTPGITVSAYDTDR---NNYYARGFSINNFQYDGIPSTARNVGYSAGNTLS 238 + D +R TPGIT A + + + RGF+ + D R+V + Sbjct: 66 ALTLADALRTTPGITFGAGEGGNPAGDRPFIRGFNAES---DTFLDGMRDVASQTREVFN 122 Query: 239 DMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVS 298 +++EV KG TGAGS G ++NLI K + GS R+ LDV+ Sbjct: 123 ----VEQIEVSKGPGSAYTGAGSTGGSLNLISKTAKQDNFTDAGFTWGSDQTRRTTLDVN 178 Query: 299 GPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADY-QDNDP 357 + ++ R + D + F + T T+ + +D Sbjct: 179 RMIGDNAAFRLNLMKHDAHVAGR-DEVSVSRWGVAPTVTFGFDTPTRATLSYYHLSTDDM 237 Query: 358 KGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLD 417 G PL +V+RS N +K +S ++ + ++ + G +++ Sbjct: 238 PDYG----LPL-------TNVNRSKANPSKPASVDRDNFYGLKDRDYRKSTTDSGTFRIE 286 Query: 418 HKINGYHAPLG-------AIMGDWPAPDNSAKIVAQKYTGETKSNS--------LDIYLT 462 H +N + PD+S VA Y + + L Sbjct: 287 HDLNDNLTLSNSTRLVRTTLDYIVSNPDDSRGNVANGYVYRSAKSRNSTSKGWVNQTDLK 346 Query: 463 GPFQFLGREHELVVGTSASFSHWEGKSYW-----NLRNYDNTTDDFINWDGDIGKPDWGT 517 F+ +H LV G S+ + Y N N + +P G Sbjct: 347 ANFETGFIKHTLVTGLEFSYEDVHNRPYAITSGGGAGNTCNARLLASGDCTSLNRPTPGD 406 Query: 518 PSQ--------YIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNP-------- 561 Y D T+ +Y+ +++ L LG R D+ Sbjct: 407 NWTGSITDGLAYTDTDTKTSAAYVFDTLKLSEQWELNLGLRYDDFDTKSSGYQTAGRNGP 466 Query: 562 ----TIRESGRF-IPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSS------NKLLEP 610 + F G VY S+Y +++ P + N L+P Sbjct: 467 AGYFKRENNSHFWNYQTGLVYKPAPNGSIYLAWSTSSNPTGETGGEGQADISVGNNGLDP 526 Query: 611 DEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKT 670 + +N E+G K + D L+ + A F + N + T + + Sbjct: 527 ERNRNLELGTKWAFFDDALSLNAALFRTDKTNARVASPDVS--------TLQVLDGEQRV 578 Query: 671 KGYEAEISGELAPGWQVQAGYTH-------KIIRDDSGKKVSTWEPQDQLSLYTSYKFKG 723 +G E +G+L W+V GYT+ ++ D G K+ Q+ +L+T+Y Sbjct: 579 QGVELGFNGKLTEKWKVFGGYTYLDSEIRKSTVKSDEGNKMPQ-TAQNNFTLWTTYDL-- 635 Query: 724 ALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNN 783 L T+GGG + K + N+ YW D MA Y+++ + +NV N Sbjct: 636 -LQNFTIGGGTTYVDKQYGNTANST-------YIPSYWRYDAMASYKVSKNVDLQLNVQN 687 Query: 784 VFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 + DK Y+ + A R + + F Sbjct: 688 LTDKRYFDQVYSTHMAHVAPGRTALLGVNFHF 719 >6BPM-C nrPDB Length = 727 Score = 371 bits (951), Expect = e-103, Method: Composition-based stats. Identities = 153/734 (20%), Positives = 260/734 (35%), Gaps = 95/734 (12%) Query: 149 PGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITV-----SAYDTD 203 + + +T +++TV++ Q + D G N+ D +++ PG+ + T Sbjct: 22 APQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTT 81 Query: 204 RNNYYARGFSINN-FQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSL 262 + Y RG +N DGI R++G + +T + ++VEV+KG +G G + Sbjct: 82 GDAIYMRGADTSNSIYIDGI----RDIGSVSRDTFNT----EQVEVIKGPSGTDYGRSAP 133 Query: 263 GATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFM 322 +IN+I K+P ++ GS R LDV+ + ++ VR + + Sbjct: 134 TGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTH-DAGR 192 Query: 323 DHYERKTSVYYGILEFDLNPDTMLTVGADY--QDNDPKGSGWSGSFPLF-------DSQG 373 D + + + F L L + + Q N P G + P + + Sbjct: 193 DKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALN 252 Query: 374 NRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGD 433 + V G + T T EH+ + + + AIMG Sbjct: 253 HSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGG 312 Query: 434 WPAPDNSAKIV--------AQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHW 485 V A K + LT F H++ G + Sbjct: 313 ASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEFTR-ET 371 Query: 486 EGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNL 545 + N + + D I + +T Y +T D L Sbjct: 372 QTNYGVNPVTLP--AVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFEL 429 Query: 546 FLGGRVVDYRVT---------------------------GLNPTIRESGRFIPYVGAVYD 578 G R+ +Y T + GA+Y Sbjct: 430 NGGIRLDNYHTEYDSATACGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYH 489 Query: 579 LNDTYSVYASYTDIFMPQ--------DSWYRDSSNKL-LEPDEGQNYEIGIKGEYLDGRL 629 L + +VY +Y P S +S+N+ +P + EIG K + LD RL Sbjct: 490 LTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRL 549 Query: 630 NTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQA 689 + A F EN E+ N TY+ G K + +GYE ++G + P WQV Sbjct: 550 LLTAALFRTDIENEVEQ---------NDDGTYSQYG-KKRVEGYEISVAGNITPAWQVIG 599 Query: 690 GYTHKIIRDDSGKKVS-------TWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQ 742 GYT + +GK V+ + P+ +L++ Y+ A D ++VG GAR+ G Sbjct: 600 GYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQ---ATDDISVGAGARYIGS--- 653 Query: 743 MVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASY- 801 M + + E YW+ D Y++ L +NV N+FD Y +I + Sbjct: 654 MHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKSGYRYHP 713 Query: 802 GDPRNLMFSTRWDF 815 G+PR + + F Sbjct: 714 GEPRTFLLTANMHF 727 >3CSL-A nrPDB Length = 865 Score = 275 bits (704), Expect = 4e-74, Method: Composition-based stats. Identities = 152/883 (17%), Positives = 282/883 (31%), Gaps = 148/883 (16%) Query: 48 FDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTGASVD 107 F+I Q L SA+ F QA +QV + ++ +++A+ G + Q + L+ G + Sbjct: 16 FNIAAQPLQSAMLRFAEQAGMQVFFDEVKLDGMQAAALNGSMSVEQGLRRLIGGNPVAFR 75 Query: 108 FQGNAITISVAEAADSSVDLGATMITS-NQLGTITEDSGSYTPGTIATATRLVLTPRETP 166 Q I ++ ++ D GA + S LG ++ + + P Sbjct: 76 LQPQG-QIVLSRLPTANGDGGALALDSLTVLGAGGNNANDWV--------------YDEP 120 Query: 167 QSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDR----NNYYARGFSINNFQYDGI 222 +S++V++R+ MD+ + D++ T G S D N + + N DG+ Sbjct: 121 RSVSVISREQMDNRPARHAADILEQTTGAYSSVSQQDPALSVNIRGIQDYGRVNMNIDGM 180 Query: 223 PSTARNVGYSAGN--TLSDMAIYDRVEVLKGATGLLTGAGSLGA--TINLIRKK----PT 274 + G+ N D + V + KG TG + AG+LG T N + P Sbjct: 181 RQNFQKSGHGQRNGTMYIDSELLSGVTIDKGTTGGMGSAGTLGGIATFNTVSASDFLAPG 240 Query: 275 HEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKH--------------- 319 E G +L A + DN + SG L GN G + A ++H Sbjct: 241 KELGG--KLHASTGDN-GTHFIGSGILA-LGNETGDILLAASERHLGDYWPGNKGDIGNI 296 Query: 320 ------SFMDHY----------ERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGS--- 360 D Y + ++ + + N + Y Sbjct: 297 RINNDTGNYDRYAESIKNNKIPDTHYRMHSRLAKVGWNLPANQRLQLSYLQTQTASPIAG 356 Query: 361 --GWSGSFPLFDSQGNRNDVSRSFNNGAKWSS--------WEQYTRTVFANLEHNFANGW 410 G+ P ++ R + A + W + ++ + ++ + Sbjct: 357 TLTNLGTRPPYELGWKRTGYTDVMARNAAFDYSLAPEDVDWLDFQAKLYYVDTQDDSDTY 416 Query: 411 VGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGR 470 LD NGY A + S +A + + L+ Y Sbjct: 417 STSSLLD---NGYATRTRLRTYGAQAQNTSRFSLAPGHDFRA-NYGLEFYYDK--ATSDS 470 Query: 471 EHELVVGTSASFSHWEGKSYWNL-RNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQL 529 + + G + + + + NL +YD D + G D + Sbjct: 471 SRQGMEGVTPAGNRSVASLFANLTYDYDGWLTLEGGLRYDRYRLR-GQTGLSYPDLAKDG 529 Query: 530 GSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTY-SVYAS 588 Y L D+ V R+ G+ P + + +Y + Sbjct: 530 QRYTIDNPCKALRLTGCSTTTREDWDVD------RDQGKLSPTLAVAVRPGVEWLELYTT 583 Query: 589 YTDIFMPQ------DSWYRDSS-----NKLLEPDEGQNYEIGIKGE-----YLDGRLNTS 632 Y + P + SS N L+P+ + +E+G + + RL Sbjct: 584 YGKSWRPPAITETLTNGSAHSSSTQYPNPFLQPERSRAWEVGFNVQQPDLWFEGDRLVAK 643 Query: 633 LAYFEIHEENRAEEDALYNSK----PTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQ 688 +AYF+ +N N P+ Y K + +G E +++ A + Sbjct: 644 VAYFDTKVDNYINLAIDRNKPGLVQPSIGNAAYVNNLSKTRFRGLEYQLN-YDAGVFYAD 702 Query: 689 AGYTHKIIRDDSGKK--------------------VSTWEPQDQL-------SLYTSYKF 721 YTH I +++ V + ++ Sbjct: 703 LTYTHMIGKNEFCSNKAWLGGRLRYGDGSRRGNFYVEPDAASNDFVTCDGGTQFGSAAYL 762 Query: 722 KGALDKLTVGG---------GARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQIT 772 G +T+GG G + + P + Y L DL A Y++T Sbjct: 763 PGDRGSVTLGGRAFDRKLDAGVTVRFAPGYQDSSVPSNYPYLADWPKYTLFDLYASYKLT 822 Query: 773 DKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 D L+ +V N+ ++ Y + G + + G R + + F Sbjct: 823 DSLTLRGSVENLTNRAYVVSYGETLANTLGRGRTVQGGVEYRF 865 >2HDF-A nrPDB Length = 639 Score = 207 bits (525), Expect = 2e-53, Method: Composition-based stats. Identities = 122/717 (17%), Positives = 232/717 (32%), Gaps = 140/717 (19%) Query: 152 IATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARG 211 + TA+ + ++ P SI+V+T++++ + N+ DV++ PG+ ++ +R RG Sbjct: 10 VVTASSVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRG 69 Query: 212 F--SINNFQYDGIPSTARNVGYSAGN---TLSDMAIYDRVEVLKGATGLLTGAGSLGATI 266 S DG +RN + + + +R+EV++G L G+ +LG + Sbjct: 70 LDSSYTLILVDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVV 129 Query: 267 NLIRKKPTHEFKGHVELGA------GSWDNYRSELDVSGPLTES-GNVRGRAVAAYQDKH 319 N+I KK ++ G V + D Y + SGPL + ++ A ++K Sbjct: 130 NIITKKIGQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKD 189 Query: 320 SFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVS 379 + T I F V + N F D + D + Sbjct: 190 DPQNSTTTDTGETPRIEGFSSRDG---NVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKN 246 Query: 380 R------SFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGD 433 R S ++ +W + +E+ Sbjct: 247 RLERQNYSVSHNGRWDYGTSELKYYGEKVENK---------------------------- 278 Query: 434 WPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNL 493 P NS+ I ++ T + K +L + F +G + Sbjct: 279 --NPGNSSPITSESNTVDGK-YTLPLTAINQFLTVG-------------GEMRHDKMSDA 322 Query: 494 RNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVD 553 N T K + +++D + + + L L G R+ D Sbjct: 323 VNLTGGTSS---------KTSASQYALFVED-----------EWRIFEPLALTTGVRMDD 362 Query: 554 YRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIF------MPQDSWYRDSSNKL 607 + G + P VY+ DT +V + F W +S Sbjct: 363 HETYG--------EHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGA 414 Query: 608 --------LEPDEGQNYEIGIKGEYLDGRL---NTSLAYFEIHEENRAEED--ALYNSKP 654 L+P+ +++E+G+ +G L +S+ F ++R + N+ P Sbjct: 415 CKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAP 474 Query: 655 TNPA--------------ITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDS 700 + Y KA+ +G E E+ W++ YT+ RD S Sbjct: 475 GYQNFVGFETGANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVS 534 Query: 701 GKKVST--WEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQE 758 + P + +K AL+ ++ + G+ Sbjct: 535 NGENKPLSDLPFHTANGTLDWK-PLALEDWSMYMSGHYTGQKRADSATAKTP-------G 586 Query: 759 DYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 Y + + A +Q+T + V N+ DK + Y D R + + F Sbjct: 587 GYTIWNTGAAWQVTKDVKLRAGVLNLGDKDLSRDDYSYNE----DGRRYFMAVDYRF 639 >1KMO-A nrPDB Length = 774 Score = 190 bits (482), Expect = 2e-48, Method: Composition-based stats. Identities = 133/835 (15%), Positives = 266/835 (31%), Gaps = 109/835 (13%) Query: 22 RRILPHSLAMALSL-PLAGY-VQAQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRN 79 R+ P + LSL PLAG A + +I P +L AL ++ + + R Sbjct: 8 RKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLDKALNQYAAHSGFTLSVDASLTRG 67 Query: 80 KRSSAIKGKLEPNQAITELLRGTGASVD-FQGNAITISVAEAADSSVDLGATMITSNQLG 138 K+S+ + G + + +LL G+G V N+ T+ A A A + + LG Sbjct: 68 KQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSWTLEPAPAPKE----DALTVVGDWLG 123 Query: 139 TITEDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVS 198 E+ E + V+ R++ G + +V+ PG++ Sbjct: 124 DAREND-----------------VFEHAGARDVIRREDFAKTGATTMREVLNRIPGVSAP 166 Query: 199 AYDTDRN-----NYYARGF-----SINNFQYDGIPSTARNVGYSA-GNTLSDMAIYDRVE 247 + + N+ RG S + DGIP G + D ++ Sbjct: 167 ENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNMDAID 226 Query: 248 VLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELG-----AGSWDNYRSELDVSGPLT 302 V++G + G S+G +N + + +F + S +N + ++ T Sbjct: 227 VVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPKETHNLMVGGT 286 Query: 303 ESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGW 362 + + + +H + ++ + Y D + G Sbjct: 287 ADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLLQYYDGEADMPG- 345 Query: 363 SGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKING 422 +SR+ + +W S Y R F + G+ + HK N Sbjct: 346 --------------GLSRADYDADRWQSTRPYDR--FWGRRKLASLGYQFQPDSQHKFNI 389 Query: 423 YHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASF 482 + + + + Y ++ + F HE+ VG Sbjct: 390 QGFYTQTLRSGYLEQGKRITLSPRNYW----VRGIEPRYSQIFMIGPSAHEVGVGYRYLN 445 Query: 483 SHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDK---TRQLGSYMTARFNV 539 Y+ + S Y D T Y+ + ++ Sbjct: 446 ESTHEMRYYTATS---------------SGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDI 490 Query: 540 TDDLNLFLGGRVVDYRV------TGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIF 593 + + G R TG + + + P + +Y L D++++YA+ F Sbjct: 491 GN-WTITPGMRFEHIESYQNNAITGTHEEVSYNAPL-PALNVLYHLTDSWNLYANTEGSF 548 Query: 594 MPQD--SWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYN 651 + + +EP++ + +E+G + + DG L + F I+ N + D+ Sbjct: 549 GTVQYSQIGKAVQSGNVEPEKARTWELGTRYD--DGALTAEMGLFLINFNN--QYDSNQT 604 Query: 652 SKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKII----RDDSGKKVSTW 707 + + G++ + + Y+ + A Y + + D+ + + Sbjct: 605 NDTVTARGKTRHTGLETQAR-YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPF 663 Query: 708 EPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNN--PRSRWEKFSQEDYWLVDL 765 P+ + +L YK T + +Q + N + + L Sbjct: 664 SPKHKGTLGVDYKP----GNWTFNLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGA 719 Query: 766 MARYQIT---DKLSASVNVNNVFDKTYYTNIGFYTS--ASYGDPRNLMFSTRWDF 815 Y L+ + V N+FD+ Y+ + G PR L F Sbjct: 720 RVAYDFGPQMADLNLAFGVKNIFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF 774 >1NQH-A nrPDB Length = 594 Score = 189 bits (479), Expect = 5e-48, Method: Composition-based stats. Identities = 114/677 (16%), Positives = 212/677 (31%), Gaps = 91/677 (13%) Query: 146 SYTPGTIATATRLVLTPRETPQS-ITVVTRQNMDDFGLNNIDDVMRHTPG--ITVSAYDT 202 +P T+ PR T + TVVTRQ++D + +++DV+R PG IT + Sbjct: 2 DTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSG 61 Query: 203 DRNNYYARGFSINNFQY--DGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAG 260 ++ + RG + ++ DG+ V SA + +A+ RVE ++G + G+ Sbjct: 62 QLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSD 121 Query: 261 SLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHS 320 ++G +N+I + E + G GS DVS R + Y H Sbjct: 122 AIGGVVNIITTR--DEPGTEISAGWGSNSYQN--YDVSTQQQLGDKTRVTLLGDYAHTHG 177 Query: 321 FMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSR 380 + D + + + D L+ WSG NR + Sbjct: 178 Y-DVVAYGNTG----TQAQTDNDGFLSKTLYGALEHNFTDAWSGFV-RGYGYDNRTNYDA 231 Query: 381 SFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNS 440 ++ G+ + ++ W ++ + ++ D Sbjct: 232 YYSPGSP-----------LLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPH 280 Query: 441 AKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTT 500 T + ++ + + H + Sbjct: 281 YGRYDSSATLDEMK----------------QYTVQWANNVIVGH-------------GSI 311 Query: 501 DDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLN 560 ++W GT R G Y+T V D + Sbjct: 312 GAGVDW--QKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGD---------FTFEGAARSD 360 Query: 561 PTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQD--SWYRDSSNKLLEPDEGQNYEI 618 + A ++ + Y ASY + + Y N L+P++ + +E Sbjct: 361 DNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEG 420 Query: 619 GIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEIS 678 +G L +N ++ + + + D Y KA+ KG EA + Sbjct: 421 AFEG--LTAGVNWRISGYRNDVSDLIDYD---------DHTLKYYNEGKARIKGVEATAN 469 Query: 679 GELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQG 738 + P Y + R+ + Q+ Y+ L G ++ G Sbjct: 470 FDTGP-LTHTVSYDYVDARNAITDTPLLRRAKQQVK----YQLDWQLYDFDWGITYQYLG 524 Query: 739 KSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTNIGFYTS 798 + Y++ ++ L DL Y +T L+ + N+FDK Y T G+ T Sbjct: 525 TRYDKDYSS--YPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQT- 581 Query: 799 ASYGDPRNLMFSTRWDF 815 R S + F Sbjct: 582 ----AGREYTLSGSYTF 594 >5FP2-A nrPDB Length = 725 Score = 182 bits (461), Expect = 6e-46, Method: Composition-based stats. Identities = 133/729 (18%), Positives = 243/729 (33%), Gaps = 95/729 (13%) Query: 149 PGTIATATRLVLTPRETPQSITVVTRQNMDDFG-LNNIDDVMRHTPGITVSAYD-----T 202 + T ++ P ++++T +++ +N++ +++R PG+ ++ Sbjct: 22 GDEVVLGTA-EQELKQAP-GVSIITAEDIRKRPPVNDLSEIIRTMPGVNLTGNSSSGQRG 79 Query: 203 DRNNYYARGFSINN--FQYDGIPSTARNVGY----SAGNTLSD-----MAIYDRVEVLKG 251 + RG N DG P ++RN +T D +R+EVL+G Sbjct: 80 NNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDTRGDSNWVPPEEVERIEVLRG 139 Query: 252 ATGLLTGAGSLGATINLIRKKPTHEFKGHVEL------GAGSWDNYRSELDVSGPLTESG 305 G+G+ G +N+I K+PT +G + + + R+ +SGPLTE+ Sbjct: 140 PAAARYGSGAAGGVVNIITKRPTDRLRGSMTVFTNIPESSKDGATRRANFSLSGPLTEAL 199 Query: 306 NVRGRAVAAYQDKH--------------SFMDHYERKTSVYYGILEFDLNPDTMLTVGAD 351 + R A D + + G+L + + PD ++ A Sbjct: 200 SFRAYGSANKTDSDDTDINLGHTVNPSRTVAGREGVRNRDLSGMLSWQVTPDQVVDFEA- 258 Query: 352 YQDNDPKGSGWSGSFPLFDSQGNRNDVSRS--FNNGAKWSSWEQYTRTVFANLEHNFANG 409 G G+ D+Q N + ++GA+ + + + N +F Sbjct: 259 -------GFSRQGNIYAGDTQNNNGTANTQGLADDGAETNRMYRENYAITHNGTWSFGTS 311 Query: 410 -WVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFL 468 +V + G++ G A D S + ++ L L P L Sbjct: 312 RFVAQYDSTRNNRLEEGLAGSVEGQIGA-DRSFS------ASKLENYRLSGELNLPLHAL 364 Query: 469 GREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQ 528 +++ + L + + F+ D G P G+ S K Sbjct: 365 F--EQVLTVGAEWNKET-------LNDPSSLKQGFVGSDSLPGTPAAGSRSP--KSKAEI 413 Query: 529 LGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGR------FIPYVGA------- 575 Y+ + L G R+ D+ GLN + + F G Sbjct: 414 RALYVEDNIELRPGTMLTPGLRLDDHSDFGLNWSPSLNASQTLGEYFTVKAGIARAFKAP 473 Query: 576 -VYDLNDTYSVYA-SYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSL 633 +Y N Y +Y N+ L+ + N E+GI E+ L Sbjct: 474 NLYQSNPNYLLYTRGNGCPIQTSSGGCYLVGNENLDAETSVNKELGI--EFRRDGWVAGL 531 Query: 634 AYFEIHEEN--RAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGY 691 YF +N A D + + N + ++ KA +G E + L Sbjct: 532 TYFRNDYKNKIVAPLDVMGQTGTGNNILQWSN-AKKAVVEGLEGNLLVPLHEDLSWSTNL 590 Query: 692 THKIIRDDSGKKVSTWE-PQDQLSLYTSYKFKGALD-KLTVGGGARWQGKSWQMVYNNPR 749 T+ + D P+ L+ ++ L +LT R + N P Sbjct: 591 TYMLQSKDKDTGNPLSVIPEYTLNSTLDWQASERLSTQLTSTIYGRQEPPKHGTSRNTPV 650 Query: 750 SRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKTYYTN--IGFYTSASYGDP-RN 806 + Y + + A Y ++ LS V+N+FDK Y +A+Y +P R Sbjct: 651 VSRK--EVGTYGIWGVSAGYTFSENLSVRGGVSNLFDKRLYRQGNSFDAGAATYNEPGRA 708 Query: 807 LMFSTRWDF 815 S F Sbjct: 709 YYVSMTTSF 717 >4EPA-A nrPDB Length = 655 Score = 181 bits (459), Expect = 1e-45, Method: Composition-based stats. Identities = 125/712 (17%), Positives = 224/712 (31%), Gaps = 92/712 (12%) Query: 138 GTITEDSGSYTPGTIATATRLVLTPRETPQ-SITVVTRQNMDDFGLNNIDDVMRHTPGIT 196 G + + S + TA++ S TVV+ + D G+ D + R PG+ Sbjct: 1 GAMGQTSQQDESTLVVTASKQSSRSASANNVSSTVVSAPELSDAGVTASDKLPRVLPGLN 60 Query: 197 VSAYDT-DRNNYYARGFS-INNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATG 254 + + RG S +F + V + NT+ + VE+L+G G Sbjct: 61 IENSGNMLFSTISLRGVSSAQDFYNPAVTLYVDGVPQLSTNTIQALTDVQSVELLRGPQG 120 Query: 255 LLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAA 314 L G + G IN++ ++P +G++E G S D+YRS+ ++SGP+ + + Sbjct: 121 TLYGKSAQGGIINIVTQQPDSTPRGYIEGGVSSRDSYRSKFNLSGPIQDGLLYGSVTLLR 180 Query: 315 YQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGN 374 D ++ D T ++G P W F Sbjct: 181 QVDDGDMIN----------PATGSDDLGGTRASIGNVKLRLAPDDQPWEMGFAA------ 224 Query: 375 RNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDW 434 SR + + G+ K++ M Sbjct: 225 ----SRECTRATQDAYVGWND--------------IKGR-----KLSISDGSPDPYMRRC 261 Query: 435 PAPDN-SAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNL 493 S K + S + + F + + + + Sbjct: 262 TDSQTLSGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNMPQRWNQDVQELRAATLGDA 321 Query: 494 RNYDNTTDDF-------INWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLF 546 R D + +N D+ + + + Y +T L +Y +++TD ++ Sbjct: 322 RTVDMVFGLYRQNTREKLNSAYDMPTMPYLSSTGYTTAET--LAAYSDLTWHLTDRFDIG 379 Query: 547 LGGRVVDYRVTGLNPTIRESGRFIPYV-----------GAVYDLNDTYSVYASYTDIFMP 595 G R + + F A Y L D + VY + P Sbjct: 380 GGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYMLTDDWRVYTRVAQGYKP 439 Query: 596 QDSWYRDSSN---KLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNS 652 ++ K ++ NYE+G + E D + A F H ++ Sbjct: 440 SGYNIVPTAGLDAKPFVAEKSINYELGTRYETAD--VTLQAATFYTHTKDMQLYSGPVRM 497 Query: 653 KPTNPAITYAYKGIKAKTKGYEAEISGELAPG--WQVQAGYTHKIIRDDS----GKKVST 706 + + KA G E E APG W + +DS G +V Sbjct: 498 QTLSN-------AGKADATGVELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRV-P 549 Query: 707 WEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLM 766 + P+ + L G + N + Q Y +D Sbjct: 550 FVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHYFDGDN-------QLRQGTYATLDSS 602 Query: 767 ARYQITDKLSASVNVNNVFDKTYYTNIGFYTSASYGD---PRNLMFSTRWDF 815 +Q T++++ SV V+N+FD+ Y T S++ R + +TR DF Sbjct: 603 LGWQATERMNISVYVDNLFDRRYRTYGYMNGSSAVAQVNMGRTVGINTRIDF 654 >5M9B-A nrPDB Length = 724 Score = 180 bits (456), Expect = 2e-45, Method: Composition-based stats. Identities = 139/751 (18%), Positives = 255/751 (33%), Gaps = 109/751 (14%) Query: 143 DSGSYTPGTIATATRLVLTPRETPQS--ITVVTRQNMDDFGL-NNIDDVMRHTPGITVSA 199 G + + T + ET Q+ ++++T +++ N++ ++R PG+ ++ Sbjct: 5 GQGDGSVIELGEQTVVATAQEETKQAPGVSIITAEDIAKRPPSNDLSQIIRTMPGVNLTG 64 Query: 200 YD-----TDRNNYYARGFSINN--FQYDGIPSTARNV--------GYSAGNTLSDMAI-Y 243 + RG N DG P ++RN S G+T A Sbjct: 65 NSSSGQRGNNRQIDIRGMGPENTLILVDGKPVSSRNSVRYGWRGERDSRGDTNWVPADQV 124 Query: 244 DRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVELGAG------SWDNYRSELDV 297 +R+EV++G G G+ G +N+I K+ E G++ + + + R + Sbjct: 125 ERIEVIRGPAAARYGNGAAGGVVNIITKQAGAETHGNLSVYSNFPQHKAEGASERMSFGL 184 Query: 298 SGPLTESGNVRGRAVAAYQDKHSF--MDHYERKTSV-----------------YYGILEF 338 +GPLTE+ + R A D + +E + G+L + Sbjct: 185 NGPLTENLSYRVYGNIAKTDSDDWDINAGHESNRTGKQAGTLPAGREGVRNKDIDGLLSW 244 Query: 339 DLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTV 398 L P+ L A G G+ D+Q ++ G + + + T +V Sbjct: 245 RLTPEQTLEFEA--------GFSRQGNIYTGDTQNTNSNNYVKQMLGHETNRMYRETYSV 296 Query: 399 FANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLD 458 E +F + L ++ + G + A YT + + Sbjct: 297 THRGEWDFGSSL---AYLQYEKTRNSRINEGLAGGTEGIFDP--NNAGFYTATLRDLTAH 351 Query: 459 IYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTP 518 + P E L +G+ + + + + + N + P Sbjct: 352 GEVNLPLHLGY-EQTLTLGSEWTEQKLD-----------DPSSNTQNTEEGGSIPGLAGK 399 Query: 519 SQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLN--PTIRESGRFIPYVGA- 575 ++ R + + L G R + + G N P++ S V Sbjct: 400 NRSSSSSARIFSLFAEDNIELMPGTMLTPGLRWDHHDIVGDNWSPSLNLSHALTERVTLK 459 Query: 576 -----------VYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEY 624 +Y LN Y +Y+ + S Y N L+ + N E+GI EY Sbjct: 460 AGIARAYKAPNLYQLNPDYLLYSRGQGCYGQSTSCYLRG-NDGLKAETSVNKELGI--EY 516 Query: 625 LDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGI-------KAKTKGYEAEI 677 L L YF +N+ E + YA I KA +G E + Sbjct: 517 SHDGLVAGLTYFRNDYKNKIESGLSPVDHASGGKGDYANAAIYQWENVPKAVVEGLEGTL 576 Query: 678 SGELAPGWQVQAGYTHKI-IRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARW 736 + LA G + T+ + ++ V + P+ L+ ++ A D L++ W Sbjct: 577 TLPLADGLKWSNNLTYMLQSKNKETGDVLSVTPRYTLNSMLDWQ---ATDDLSLQATVTW 633 Query: 737 QGKSWQMVYNNPRSRWEKFSQED---YWLVDLMARYQITDKLSASVNVNNVFDKTYYT-- 791 GK Y+ R + + Y + L Y+++ LS V+N+FDK + Sbjct: 634 YGKQKPKKYDYHGDRVTGSANDQLSPYAIAGLGGTYRLSKNLSLGAGVDNLFDKRLFRAG 693 Query: 792 ------NIGFYTSASYGDP-RNLMFSTRWDF 815 I +A+Y +P R S F Sbjct: 694 NAQGVVGIDGAGAATYNEPGRTFYTSLTASF 724 >5FR8-A nrPDB Length = 733 Score = 165 bits (418), Expect = 5e-41, Method: Composition-based stats. Identities = 143/758 (18%), Positives = 247/758 (32%), Gaps = 120/758 (15%) Query: 142 EDSGSYTPGTIATATRLVLTPRETPQS--ITVVTRQNMDDFGL-NNIDDVMRHTPGITVS 198 E + + T V + QS ++V+T+++++ + N+I D +R PG+ ++ Sbjct: 12 EQTLEKPAEPVKLETIFVTAEEQVKQSLGVSVITKEDLEKLPVRNDISDYVRRMPGVNLT 71 Query: 199 AYD-----TDRNNYYARGFSINN--FQYDGIPSTARNVG----YSAGNTLSDM-----AI 242 + RG N DG P +RN +T D Sbjct: 72 GNSATGQRGNNRQIDIRGMGPENTLILVDGKPINSRNSVRYGWKGERDTRGDSNWVPAEA 131 Query: 243 YDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL------GAGSWDNYRSELD 296 + +EVL+G G+G+ G +N+I KK T+E G VE + + R + Sbjct: 132 IESIEVLRGPAAARYGSGAAGGVVNIITKKVTNETHGSVEFYTSQPEDSKEGSSNRVGFN 191 Query: 297 VSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDND 356 VSGPL + + R Y + D + S+ + + ++ +Q D Sbjct: 192 VSGPLIKD-VLSYRLYGNYNKTEA--DDVDINKSIGSTAAGREGVKNKDISGRLAWQATD 248 Query: 357 PKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWS-------SWEQYT-RTVFANLEHNFAN 408 + S QGN N A+ E T L H Sbjct: 249 QQTVLLDIS---SSKQGNIYSGDSQLNANAEADAILSQLIGKETNTMYRDSYALTHEGDW 305 Query: 409 GWVGKVQLDHKINGYH------APLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLT 462 W GK +L + + H G++ G D+ A + + Sbjct: 306 SW-GKSKLVAQYDKTHNKRLPEGLAGSVEGKINNLDDKATSRLETLRFNGE-------AN 357 Query: 463 GPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDG-DIGKPDWGTPSQY 521 PF++ L VGT D D+ G D +G Sbjct: 358 IPFEYY-LPQVLTVGTEWVE--------------DRFKDNVSTTQGKDSSGSGYGDQLAK 402 Query: 522 IDDKTRQL---GSYMTARFNVTDDLNLFLGGRVVDYRVTGLNP------TIRESGRFIPY 572 D + +Y+ VTD ++ LG R D+ +G N T + + F Sbjct: 403 GDRSKMESRIASAYIEDNLKVTDSTDVVLGLRFDDHSKSGSNWSPSLNITQKLNDYFTLK 462 Query: 573 VGA--VYDLNDTYSVYASYTDIFM----PQDSWYRD--SSNKLLEPDEGQNYEIGIKGEY 624 G Y + Y Y P + R N L+P+ N E+GI ++ Sbjct: 463 GGVAKAYKAPNMYQNAEGYLLSTNGNGCPANIESRCLLQGNGDLKPETSVNKELGI--QF 520 Query: 625 LDGRLNTSLAYFEIHEENRAEE------DALYNSKPTNPAITYAYK--------GIKAKT 670 +N SL +F +++ +S N K KA Sbjct: 521 QKDIVNASLTWFRNDYKDKIVAGTHVVGTVDGSSTNANTGAVTNTKWNILRWENTPKALI 580 Query: 671 KGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYT-----SYKFKGAL 725 +G+E + G + +T+ + K T P + +YT Y L Sbjct: 581 QGFEGSL-GLDFGDIRWTNNFTYMM----DSKDKQTGNPLSLVPIYTINSIFDYDITDQL 635 Query: 726 D-KLTVGGGARWQGKSW-------QMVYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSA 777 D R + + + + S + + + Y + Y+ +D++S Sbjct: 636 DVNFVFTQYGRQKSRQFAENRLESGIGSGGANSALKPSTVKSYSTAGINVGYKFSDQIST 695 Query: 778 SVNVNNVFDKTYYTNIGFYTSASYGDPRNLMFSTRWDF 815 V V+N+FDK + + R S ++ F Sbjct: 696 RVGVSNLFDKQILRDSNSISQTYNEPGRAYYASLKYSF 733 >1FEP-A nrPDB Length = 724 Score = 163 bits (413), Expect = 2e-40, Method: Composition-based stats. Identities = 120/754 (15%), Positives = 229/754 (30%), Gaps = 111/754 (14%) Query: 142 EDSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGL-NNIDDVMRHTPGITVSAY 200 E + + + P ++ +T + + ++ ++R PG+ ++ Sbjct: 2 EPTDTPVSHDDTIVVTAAEQNLQAP-GVSTITADEIRKNPVARDVSKIIRTMPGVNLTGN 60 Query: 201 D-----TDRNNYYARGFSINN--FQYDGIPSTARNVG----YSAGNTLSD-----MAIYD 244 + RG N DG P ++RN +T D + + Sbjct: 61 STSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIE 120 Query: 245 RVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKGHVEL------GAGSWDNYRSELDVS 298 R+EVL+G G G+ G +N+I KK + E+ G + R+ ++ Sbjct: 121 RIEVLRGPAAARYGNGAAGGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLT 180 Query: 299 GPLTESGNVRGRAVAAYQDKHSF---MDHYERKTSVYY----------------GILEFD 339 GPL + + R ++ H + Y G++ +D Sbjct: 181 GPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWD 240 Query: 340 LNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQG-NRNDVSRSFNNGAKWSSWEQYTRTV 398 P L + A Y G+ D+Q N + +RS + Q Sbjct: 241 FAPLQSLELEAGYSR--------QGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALT 292 Query: 399 FANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTG-ETKSNSL 457 + GW V + + H I + + + Sbjct: 293 -------WNGGWDNGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDV 345 Query: 458 DIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGT 517 ++ ++ + + N + T N G I Sbjct: 346 MLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLSSNTQALTGT-----NTGGAIDGVSTTD 400 Query: 518 PSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVV-------DYRVT-------GLNPTI 563 S Y K + +TD + G R ++ G + T+ Sbjct: 401 RSPY--SKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTL 458 Query: 564 RESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGE 623 + ++Y N Y +Y+ + Y ++ L+ + N EIG+ E Sbjct: 459 KMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDD-LKAETSINKEIGL--E 515 Query: 624 YLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGI-KAKTKGYEAEISGELA 682 + + +F N+ E + + Y + + KA +G E ++ ++ Sbjct: 516 FKRDGWLAGVTWFRNDYRNKIEAGYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVS 575 Query: 683 PGWQVQAGYTHKI-IRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSW 741 T+ + + + + P+ L+ S++ A + L++ W GK Sbjct: 576 ETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQ---AREDLSMQTTFTWYGKQQ 632 Query: 742 QMVYN---NPRSRWEKFSQEDYWLVDLMARYQITDKLSASVNVNNVFDKT---------- 788 YN P E Y +V L A + +T +S + V+N+FDK Sbjct: 633 PKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTT 692 Query: 789 -------YYTNIGFYTSASYGDPRNLMFSTRWDF 815 Y G YT G R S F Sbjct: 693 GDLAGANYIAGAGAYTYNEPG--RTWYMSVNTHF 724 >3FHH-A nrPDB Length = 640 Score = 150 bits (379), Expect = 2e-36, Method: Composition-based stats. Identities = 115/689 (16%), Positives = 218/689 (31%), Gaps = 91/689 (13%) Query: 148 TPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYD-TDRNN 206 T TAT + E P ++V+ ++ + D++RH PGIT+ T+ + Sbjct: 1 TETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQD 60 Query: 207 YYARGFSINN--FQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGA 264 RG+ DGI + G+ G T D A+ RVE+++G + LL G+G+LG Sbjct: 61 INMRGYDHRGVLVLVDGIRQG-TDTGHLNG-TFLDPALIKRVEIVRGPSALLYGSGALGG 118 Query: 265 TINLIRK------KPTHEFKGHVELGAGSWDNYRS----ELDVSGPLTESGNVRGRAVAA 314 I+ + V G+ D+ + L R Sbjct: 119 VISYDTVDAKDLLQEGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGD 178 Query: 315 YQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGN 374 + + + + + ++ L+ Y +ND + Sbjct: 179 LRQSNGETAPNDESINNMLAKGTWQIDSAQSLSGLVRYYNNDAREP----------KNPQ 228 Query: 375 RNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDW 434 + S S N S+ ++ + + N W+ D KI + A Sbjct: 229 TVEASESSNPMVDRSTIQRDAQLSYKLAPQ--GNDWL---NADAKIYWSEVRINA----- 278 Query: 435 PAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLR 494 +S + Q G N ++ H L G +G + + Sbjct: 279 QNTGSSGEYREQITKGARLENRSTLFADS-----FASHLLTYGGEYYRQE-QGSHHHHHH 332 Query: 495 NYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTD-DLNLFLGGRVVD 553 + T F D ++ + D + L G R Sbjct: 333 HPGGATTGFPQAKIDF------------------SSGWLQDEITLRDLPITLLGGTRYDS 374 Query: 554 YRVTGLNPTIRESGRFIPYVGAVYDLNDTYSVYASYTDIFMPQD--SWYRDSS------- 604 YR + ++ ++ G + + ++ SY F Y DS Sbjct: 375 YRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRF 434 Query: 605 -------NKLLEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNP 657 N L P+ + E G + D L+ F+ + +D + + Sbjct: 435 YTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFDTKAKDYISTTVDFAA 494 Query: 658 AITYAYKGIKAKTKGYEAEISGELAPGWQVQAGYTHKIIRD-DSGKKVSTWEPQDQLSLY 716 A T +Y AK G++ ++ + + Y +D D+G+ +S+ P ++ Sbjct: 495 ATTMSYNVPNAKIWGWDV-MTKYTTDLFSLDVAYNRTRGKDTDTGEYISSINPD---TVT 550 Query: 717 TSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSRWEKFSQEDYWLVDLMARYQIT---D 773 ++ A +VG + + + Q Y + D YQ Sbjct: 551 STLNIPIAHSGFSVGWVGTFADR-------STHISSSYSKQPGYGVNDFYVSYQGQQALK 603 Query: 774 KLSASVNVNNVFDKTYYTNIGFYTSASYG 802 ++ ++ + N FDK Y++ G G Sbjct: 604 GMTTTLVLGNAFDKEYWSPQGIPQDGRNG 632 >2M5J-A nrPDB Length = 107 Score = 130 bits (326), Expect = 3e-30, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 2/103 (1%) Query: 43 AQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGT 102 AQ+ F+I Q L SA+ F QA +QV + ++ +++A+ G + Q + L+ G Sbjct: 6 AQQKNFNIAAQPLQSAMLRFAEQAGMQVFFDEVKLDGMQAAALNGSMSVEQGLRRLIGGN 65 Query: 103 GASVDFQGNAITISVAEAADSSVDLGATMITS-NQLGTITEDS 144 + Q I ++ ++ D GA + S LG ++ Sbjct: 66 PVAFRLQPQG-QIVLSRLPTANGDGGALALDSLTVLGAGGNNA 107 >2A02-A nrPDB Length = 82 Score = 117 bits (292), Expect = 3e-26, Method: Composition-based stats. Identities = 33/81 (40%), Positives = 50/81 (61%) Query: 43 AQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGT 102 +QE DIP Q++ SALQ +Q D Q+LY PE++ RSSA+KG+ + ++ LL+GT Sbjct: 1 SQEWTLDIPAQSMNSALQALAKQTDTQLLYSPEDIGGLRSSALKGRHDLQSSLRILLQGT 60 Query: 103 GASVDFQGNAITISVAEAADS 123 G GN +T++ + AA Sbjct: 61 GLRYQIDGNTVTVTASAAAKD 81 >6FOK-A nrPDB Length = 723 Score = 113 bits (281), Expect = 5e-25, Method: Composition-based stats. Identities = 111/695 (15%), Positives = 220/695 (31%), Gaps = 89/695 (12%) Query: 163 RETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARGF--SINNFQYD 220 + +P +I ++ ++ D ++ PG V + RG S N + Sbjct: 76 QSSPLTIVTNPKEPRQPVPASDGADYLKTIPGFAVIRNGGSNGDPVLRGMFGSRLNILTN 135 Query: 221 G-IPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTH--EF 277 G + A A + YD++ V+KG +L G G+ TI L ++P E Sbjct: 136 GGMMLGACPNRMDAPTSYISPETYDKLTVIKGPQTVLWGPGASAGTI-LFEREPERFGEL 194 Query: 278 KGHVELG--AGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGI 335 V AGS + LD +GN G + H+ D YE Sbjct: 195 GSRVNASLLAGSNGRFDKVLD-----AAAGNRLGYL--RFTGNHAQSDDYEDGAGNTVPS 247 Query: 336 LEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQ-----GNRNDVSRSFNNGAKWSS 390 N D G P D+ G + +R G S Sbjct: 248 RWKKWNGDV-----------------AVGWTPDEDTLIELTAGKGDGEARYAGRGMDGSQ 290 Query: 391 WEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTG 450 +++ + + + + + KV+ N + P P ++ Sbjct: 291 FKRES--LGLRFVKSNVSDVLEKVEAQVYYNYADHIMDNFRLRTPDPS---SMMPMPMAS 345 Query: 451 ETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWE---------GKSYWNLRNYDNTTD 501 + +L L +++ + LV G A + Y + + + D Sbjct: 346 QVDRRTLGGRLAATWRWDDFK--LVTGVDAMRNEHRARGSKYDMMTDYYTDADQFPWSKD 403 Query: 502 DFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNP 561 + G G+ W + ++ R +G R +V D G + Sbjct: 404 AVFHNYGAFGELTW-----FAAERDRLIGGLRLDRASVKDYRQTLKSGHMGHAMANPTAN 458 Query: 562 TIRESGRFIPYVGAVYDLNDT-YSVYA---------SYTDIFMPQDSWYRDSSN-KLLEP 610 R +V +DL D+ ++YA Y ++F P+ + ++P Sbjct: 459 DTRADTLPSGFVRYEHDLADSPTTLYAGLGHAERFPDYWELFSPKRGPNGSVNAFDKIKP 518 Query: 611 DEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKT 670 ++ + G++ +L + + ++ L++ + + + A+ Sbjct: 519 EKTTQLDFGLQYN--GDKLQAWASGY----VGVVQDFILFSYREGMMGSSTQATNVDARI 572 Query: 671 KGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTV 730 G E S +L W+ A + ++ S + P + +Y+ + Sbjct: 573 MGGELGASYQLTGNWKTDASLAYAWGKNSSDDRALPQIPPLEARFGLTYE----EGDWSA 628 Query: 731 GGGARWQGKSWQMVYNNPRSRWEKF-SQEDYWLVDLMARYQITDKLSASVNVNNVFDKTY 789 G R ++ + + F + + L Y++T + S V+N+FDK Y Sbjct: 629 GSLWRVVAPQNRIARDQGNVVGKDFDKSAGFGVFSLNGAYRVTRNVKLSAGVDNLFDKDY 688 Query: 790 YTNIGFYTSASYGD---------PRNLMFSTRWDF 815 ++ A +G R + F Sbjct: 689 TEHLNKAGDAGFGFSANETVPEPGRTFWTKVDFSF 723 >4AIP-A nrPDB Length = 742 Score = 110 bits (274), Expect = 3e-24, Method: Composition-based stats. Identities = 120/734 (16%), Positives = 222/734 (30%), Gaps = 52/734 (7%) Query: 122 DSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRE-TPQSITVVTRQNMDDF 180 ++ + S LGT +D + + T V R+ + +VT Q D+ Sbjct: 21 TAAAKFERQHMDSPDLGTDDDDKMAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDES 80 Query: 181 GLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSIN--NFQYDGIPSTARNVGYSAGNTLS 238 ++ ++++ P I + RG N + + D S ++ + Y G + Sbjct: 81 TATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNAYSDSQ-ILYHQGRFIV 139 Query: 239 DMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKG-HVELGA---GSWDNYRSE 294 D A+ V V KGA G G+ I KG G + + Sbjct: 140 DPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNNGV 199 Query: 295 LDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQD 354 + + GN + +Y + G + + A Sbjct: 200 SYGASVFGKEGNF--DGLFSYNRNDEKDYEAGKGFRNVNGGKTVPYSALDKRSYLAKIGT 257 Query: 355 NDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKV 414 + D V F G K S + Sbjct: 258 TFGDDDHRIVLSHMKDQHRGIRTVREEFTVGDKSSRINIDRQAPAYRETTQSNTNLAYTG 317 Query: 415 QLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSLDIYLTGPFQFLGREHEL 474 + + A + + + D+S A G + F E L Sbjct: 318 KNLGFVEKLDANAYVLEKERYSADDSGTGYAGNVKGPNHTRITTRGANFNFDSRLAEQTL 377 Query: 475 V-VGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIG---------KPDWGTPSQYIDD 524 + G + + +++ N + TT++ D D + + Sbjct: 378 LKYGINYRHQEIKPQAFLNSKFSIPTTEEKNGQKVDKPMEQQMKDRADEDTVHAYKLSNP 437 Query: 525 KTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVYDLNDTYS 584 G Y+ A ++ D L G R ++V + S P G ++ ++ +S Sbjct: 438 TKTDTGVYIEAIHDIGD-FTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGVIWQPHEHWS 496 Query: 585 VYASYT---------DIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLDGRLNTSLAY 635 AS+ D S + + +N EIG DG + +Y Sbjct: 497 FSASHNYASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYN--DGTFAANGSY 554 Query: 636 F-EIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEIS---GELAPGWQVQAGY 691 F + ++ A ++S A K GYE S G L V Sbjct: 555 FWQTIKDALANPQNRHDSVAVRE----AVNAGYIKNHGYELGASYRTGGLTAKVGVSHSK 610 Query: 692 THKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGAL----DKLTVGGGARWQ----GKSWQM 743 D K+ + P+ + ++ A L +G R+ G Sbjct: 611 PRFY--DTHKDKLLSANPEFGAQVGRTWTASLAYRFQNPNLEIGWRGRYVQKATGSILAA 668 Query: 744 VYNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVN--VNNVFDKTYYTNIGFYTSASY 801 + + E ++ + + D+ A ++ K + +VN VNNVF+K YY + +T+ Sbjct: 669 GQKDRKGNLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNKFYYPHSQRWTNTLP 728 Query: 802 GDPRNLMFSTRWDF 815 G R++ + F Sbjct: 729 GVGRDVRLGVNYKF 742 >4B7O-A nrPDB Length = 745 Score = 108 bits (268), Expect = 1e-23, Method: Composition-based stats. Identities = 127/742 (17%), Positives = 236/742 (31%), Gaps = 65/742 (8%) Query: 122 DSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRE-TPQSITVVTRQNMDDF 180 ++ + S LGT +D + + T V R+ + +VT Q D+ Sbjct: 21 TAAAKFERQHMDSPDLGTDDDDKMAENNAKVVLDTVTVKGDRQGSKIRTNIVTLQQKDES 80 Query: 181 GLNNIDDVMRHTPGITVSAYDTDRNNYYARGFSIN--NFQYDGIPSTARNVGYSAGNTLS 238 ++ ++++ P I + RG N + + D S ++ + Y G + Sbjct: 81 TATDMRELLKEEPSIDFGGGNGTSQFLTLRGMGQNSVDIKVDNAYSDSQ-ILYHQGRFIV 139 Query: 239 DMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHEFKG-----HVELGAGSWDNYRS 293 D A+ V V KGA G G+ I KG V L +G N Sbjct: 140 DPALVKVVSVQKGAGSASAGIGATNGAIIAKTVDAQDLLKGLDKNWGVRLNSGFASNEGV 199 Query: 294 ELDVSGPLTESGNVRGRAVAAYQDKHSF--------MDHYER------KTSVYYGILEFD 339 S + GN G D+ + + + Y + Sbjct: 200 SYGAS-VFGKEGNFDGLFSYNRNDEKEYEAGKGFRNFNGGKTVPYSALDKRSYLAKIGTT 258 Query: 340 LNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKW-SSWEQYTRTV 398 V + +D F + D+ +R +++R + + + T Sbjct: 259 FGDGDHRIVLSHMEDQHRGIRTVREEFTVGDA-SSRTNITR---QAPPYRETTQSNTNLA 314 Query: 399 FANLEHNFANGWVGKV-QLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGETKSNSL 457 + + F L+ K G+ P N +I + S Sbjct: 315 YTGKDLGFVEKLDANAYVLEKKRYSADDKDNGYAGNVVGP-NHTRITTRGMNFNFDSRLA 373 Query: 458 DIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGT 517 + L + H+ + + +E D + + K D Sbjct: 374 EQTLL-KYGI-NYRHQEIKPQAFLNGEFEISGKKKDPKDPKKEIDKTDEEKAKDKKDMDL 431 Query: 518 PSQY--IDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGA 575 Y + G+Y+ A + D L G R ++V + S P G Sbjct: 432 VHSYKLSNPTKTDTGAYIEAIHEL-DGFTLTGGLRYDRFKVKTHDGKTVSSSNLNPSFGV 490 Query: 576 VYDLNDTYSV-----YASYT----DIFMPQDSWYRDSSNKLLEPDEGQNYEIGIKGEYLD 626 ++ ++ +S YAS + D S + + +N EIG D Sbjct: 491 IWQPHEHWSFSSSHNYASRSPRLYDALQTHGKRGIISIADGTKAERARNTEIGFNYN--D 548 Query: 627 GRLNTSLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEIS---GELAP 683 G + +YF ++ A ++ + A+ A K GYE S G L Sbjct: 549 GTFAANGSYFWQTIKDAL---ANPQNRHVSAAVREAVNAGYIKNHGYELGASYRTGGLTA 605 Query: 684 GWQVQAGYTHKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGAL----DKLTVGGGARWQGK 739 V D KK+ + P+ + ++ A L +G R+ K Sbjct: 606 KVGVSHSKPRFY--DTHPKKLLSANPEFGAQVGRAWTASLAYRFQNPNLEIGWRGRYVQK 663 Query: 740 SWQMV----YNNPRSRWEKFSQEDYWLVDLMARYQITDKLSASVN--VNNVFDKTYYTNI 793 + + + + E ++ + + D+ A ++ K + +VN VNNVF+ YY + Sbjct: 664 AVGSILVAGQKDRNGKLENVVRKGFGVNDVFANWKPLGKDTLNVNLSVNNVFNTFYYPHS 723 Query: 794 GFYTSASYGDPRNLMFSTRWDF 815 +T+ G R++ + F Sbjct: 724 QRWTNTLPGVGRDVRLGVNYKF 745 >3V8X-A nrPDB Length = 904 Score = 66.0 bits (159), Expect = 5e-11, Method: Composition-based stats. Identities = 80/607 (13%), Positives = 141/607 (23%), Gaps = 125/607 (20%) Query: 324 HYERKTSVYYGIL-----EFDLNPDTMLTVGADY-------QDNDPKGSGWSGSFPLFDS 371 +E K GIL FD T+ Q G+G + Sbjct: 308 RFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANKKQAGSLPGNGKYAGNHKYGG 367 Query: 372 QGNRNDVSRSFNNGAKWSS---WEQYTRTVFANLEHNFA----NGWVGKVQLDHKINGYH 424 + GA++ + +++ LE+ + + W +L + G Sbjct: 368 LFTNGE--NGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGVG 425 Query: 425 APLGAIMGDWPAPD------NSAKIVAQKYTGET-----KSNSLDIYLTGPFQFLGREHE 473 A SA Y + L F H Sbjct: 426 LDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDTAKIRHN 485 Query: 474 LVVGT------------SASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDW------ 515 L V + H ++ I+ +G P W Sbjct: 486 LSVNLGFDRFGSNLRHQDYYYQHAN--RAYSSNTPPQNNGKKISPNGSETSPYWVTIGRG 543 Query: 516 ------------GTPSQYIDDKTRQLGSYMT--ARFNVTDDLNLFLGGRVVDYRVTGLNP 561 T + Y + ++ G R + Sbjct: 544 NVVTGQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDG 603 Query: 562 TIRESGR--FIPYVGAVYDLNDTYSVYASYTDIFMPQD-------SWYRDSSNKLLEPDE 612 ++ G V D + + F S ++P++ Sbjct: 604 SVSTGTHRTLSWNAGIVLKPTDWLDLTYRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEK 663 Query: 613 GQNYEIGI--KGEYLDGRLNTSLAYFEIHEENRAEEDALYNSKPTNP---AITYAYKGIK 667 N E GI KG++ N ++F + K Sbjct: 664 SFNKEAGIVFKGDFG----NLEASWFNNAYRDLIVRGYEAQIKDGKEEAKGDPAYLNAQS 719 Query: 668 AKTKGYEAEIS-------GELAPGWQVQAGYTHKIIRDDSGKKVSTWEPQDQLS------ 714 A+ G +L GW Y +RD + T Sbjct: 720 ARITGINILGKIDWNGVWDKLPEGWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSR 779 Query: 715 --LYTSYKFKGALDKLTVGGGARWQ---------GKSWQMVYNNPRSRWEKFSQEDYWLV 763 + Y K V G + G + N+ ++ +++V Sbjct: 780 YVVGLGYDQPE--GKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIV 837 Query: 764 DLMARYQITDKLSASVNVNNVFDKTY--YTNIGFYT------------SASYGDP-RNLM 808 D+ Y + + V N+ + Y + N+ Y P RN Sbjct: 838 DVSGYYTVKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYT 897 Query: 809 FSTRWDF 815 FS + F Sbjct: 898 FSLEYKF 904 Score = 59.5 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 35/160 (21%), Positives = 56/160 (35%), Gaps = 17/160 (10%) Query: 171 VVTRQNMDDFGLNNIDDVMRHTPGITV-SAYDTDRNNYYARGFSIN--NFQYDGIPS--- 224 V + + + NI D+ R+ PGI V + Y RG N + DG+ Sbjct: 51 VKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQS 110 Query: 225 --------TARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKKPTHE 276 R G S + VE+ KG+ + G+G+L ++ K Sbjct: 111 YTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDV 170 Query: 277 FKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQ 316 + G S Y + + LT+S + GR A Sbjct: 171 IGEGRQWGIQSKTAYSGK---NRGLTQSIALAGRIGGAEA 207 >4RDT-A nrPDB Length = 748 Score = 63.0 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 29/208 (13%), Positives = 67/208 (32%), Gaps = 21/208 (10%) Query: 143 DSGSYTPGTIATATRLVLTPRETPQSIT-----------VVTRQNMDDFGLNNIDDVMRH 191 GS+ + + + P++ + +++ + N+ D + Sbjct: 11 PRGSHETEQSVDLETVSVVGKSRPRATSGLLHTSTASDKIISGDTL-RQKAVNLGDALDG 69 Query: 192 TPGITVSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLS--DMAIYDRVEVL 249 PGI S Y + RG + + ++ + + D A+ +VE+L Sbjct: 70 VPGIHASQYGGGASAPVIRGQTGRRIKVLNHHGETGDMADFSPDHAIMVDTALSQQVEIL 129 Query: 250 KGATGLLTGAGSLGATIN-----LIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTES 304 +G LL +G++ ++ + K P + G + L S + + + Sbjct: 130 RGPVTLLYSSGNVAGLVDVADGKIPEKMPENGVSGELGLRLSSGNLEKLT-SGGINIGLG 188 Query: 305 GNVRGRAVAAYQ-DKHSFMDHYERKTSV 331 N Y+ + Y + Sbjct: 189 KNFVLHTEGLYRKSGDYAVPRYRNLKRL 216 >2D1U-A nrPDB Length = 104 Score = 48.7 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 22/99 (22%), Positives = 41/99 (41%), Gaps = 5/99 (5%) Query: 47 EFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTGASV 106 + +I P +L AL ++ + + R K+S+ + G + + +LL G+G V Sbjct: 2 QVNIAPGSLDKALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQV 61 Query: 107 D-FQGNAITISVAEAADSSVDLGATMITSNQLGTITEDS 144 N+ T+ A A A + + LG E+ Sbjct: 62 KPLGNNSWTLEPAPAPKE----DALTVVGDWLGDAREND 96 >1ZZV-A nrPDB Length = 80 Score = 44.1 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 30/65 (46%) Query: 47 EFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPNQAITELLRGTGASV 106 + +I P +L AL ++ + + R K+S+ + G + + +LL G+G V Sbjct: 2 QVNIAPGSLDKALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQV 61 Query: 107 DFQGN 111 GN Sbjct: 62 KPLGN 66 >5FQ8-B nrPDB Length = 984 Score = 42.6 bits (98), Expect = 8e-04, Method: Composition-based stats. Identities = 29/169 (17%), Positives = 58/169 (34%), Gaps = 21/169 (12%) Query: 143 DSGSYTPGTIATATRLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMR-HTPGITVSAYD 201 + TA + + + + T V + + + +++ + G+ +S+ Sbjct: 18 SDAQQIDEVVVTAMGIKRSEKALGYAATSVGGEKIAESRTSDVMSSLAGKIAGVQISSTS 77 Query: 202 TDR---NNYYARGFSINN------FQYDGIPST--------ARNVGYSAGNTLSD--MAI 242 +D N+ RG S + + DG+P N GY GN + Sbjct: 78 SDPGASNSVIIRGVSSLSGTNQPLYVVDGVPLNNSTVYSTDGLNSGYDFGNGANAINPDD 137 Query: 243 YDRVEVLKGATG-LLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDN 290 + +LKGA L G+ + + + K E +E G + Sbjct: 138 VANMTILKGAAATALYGSRAANGVVMITTKSGRKEKGVGIEYNGGVQWS 186 Score = 41.8 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 73/507 (14%), Positives = 143/507 (28%), Gaps = 82/507 (16%) Query: 279 GHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYYGILEF 338 G + A S+D Y S ++G + + Y +++ + Sbjct: 281 GMIPTDADSYDKYTFSARGS---HKAGALTFSSSLNYA---YQKNNFATTGQGLSMLNSL 334 Query: 339 DLNPDTMLTVGADYQDNDPKGSGWS-----GSFPLFDSQGNRNDVSRSFNNGA---KWSS 390 P + +G + Q++ G+ P + N+ G + Sbjct: 335 YQTPRDISIIGLEDQNDPFNTPGYYYTPYGVMNPYYILNNYLNEYESERFYGKFQLDYEF 394 Query: 391 WEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDW-PAPDNSAKIVAQKYT 449 + + T L+ GK L + + P G G P + + Q Sbjct: 395 LKYFKFTYRMGLDTTTGQSDKGKPNL-YALYYEGTPNGEGQGSSSPFSGETGQYSEQITR 453 Query: 450 GETKSNSLDIYLTGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGD 509 + + + P +VG F+ E K + Y D I + Sbjct: 454 RREINQDIMVNFNMPVNDFNI--NALVG----FNGNERKVSYQ---YSEVNDLTIPTWFN 504 Query: 510 IGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRF 569 + + + R +G + + + L L + R + T+ + R Sbjct: 505 LKNSGKTPIVEQHMELRRLMGVFGQFEGSWKNMLYLTVTARNDW------SSTLPKENRS 558 Query: 570 IPYVGAV------YDLNDTYSVYASYTDIFMP------------QDSWYRDSSNKL---- 607 Y G LND ++ I + Y SSN++ Sbjct: 559 FFYPGITGSFIFSELLNDNLQDVITFGKIRASWGKTGNDADVYMVNPVYAQSSNRIPFGS 618 Query: 608 ---------------------LEPDEGQNYEIGIKGEYLDGRLNTSLAYFEIHEENRAEE 646 L P+ E+G+ + RL+ ++Y+ + + + Sbjct: 619 LTFPLGGVNAYSAGNVLGSNTLSPEMTTESEVGLNMAFFKNRLSFDVSYYNRNTDKQIFS 678 Query: 647 DALYNSKPTNPAITYAYKG-IKAKTKGYEAEISGELAPGWQVQAGYTHKIIRDDSGKKVS 705 A+ + T K + +G E ISG T ++ S Sbjct: 679 LAMDPA----SGYTAQNMNLGKIRNRGIELLISGTPIRTKDFSWELTWNFTKNWS---KV 731 Query: 706 TWEPQDQLSLYTSYKFKGALDKLTVGG 732 P++ + T Y G + G Sbjct: 732 ISLPEELGGITTIYGLNGGTSMYAITG 758 >4ZGV-A nrPDB Length = 868 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 61/438 (13%), Positives = 116/438 (26%), Gaps = 76/438 (17%) Query: 130 TMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQSIT----VVTRQNMDDFGLN-- 183 T NQ E + + + + R TP S + ++ + + Sbjct: 26 TSADENQQKNNAESEEEQQGDSSSGNSEDTILVRSTPTSQSMGMQIINAEQIKKMPTGNG 85 Query: 184 NIDDVMRHTPGITVSAYDTDRNNYYA----------RGFSINNFQYDGIP---------- 223 ++ +++++ P + S + N F NNF DG+ Sbjct: 86 SVTELLKNNPNVQFSNTASSSNIPGELAPENVSFHGEKFYNNNFMVDGLSNNNNINPGAN 145 Query: 224 -----------STARNVGYSAGNTLSDMAIYDRVEVLKGATGLLTGAGSLGATINLIRKK 272 S A + + + + +EV G G ++ Sbjct: 146 NGELNQQPDGYSPADLPAGGPQSFWINSELIESLEVFDSNISAKYG-DFTGGVVDAKTMD 204 Query: 273 PT-HEFKGHVELGA--GSWDNYRSELDVSGPLTESGN-----------VRGRAVAAYQDK 318 P + G + SW Y +S N DK Sbjct: 205 PKLDKSSGKISYRTTRDSWTKYHISEVISEEFYSGTNLYYQPKFKKHFYSATFNQPLSDK 264 Query: 319 HSFMDHYERKTS--VYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRN 376 F+ Y R+ S YY + + + SG S Sbjct: 265 AGFIFAYNRQQSDIPYYHEYLQQWDDQERINETYLLKGTYLTDSGDIIRMTGMYSPHESK 324 Query: 377 DVSRSFNNGAKWSS-------WEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGA 429 + NG +S E + + + + + +H+ + Y Sbjct: 325 FYKKDVKNGGFTNSGGGYRFNMEWEHNASWGKMTSLAGYQYT-EDKTEHEADSYQTWRRF 383 Query: 430 IMG------DWPAPDNSAK---IVAQ--KYTGETKSNSL--DIYLTGPFQFLGREHELVV 476 G DW + + + + T S SL D L P + G H++ Sbjct: 384 SSGFVSNVIDWSSSGGANGQNSNIGGYGSFATNTSSFSLKQDYELN-PVSWYGINHQIDF 442 Query: 477 GTSASFSHWEGKSYWNLR 494 G F + + ++ Sbjct: 443 GWETDFYTSRYRRFSDVY 460 >5D0Q-A nrPDB Length = 810 Score = 37.9 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 75/541 (13%), Positives = 156/541 (28%), Gaps = 57/541 (10%) Query: 99 LRGTGASVDFQGNAITISVAEAADSSVDLGATMITSNQLG--TITEDSGSYTPGTIATAT 156 + T S+ I ++V L ++ N G E PG + T Sbjct: 240 IDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGNLAGHSAEIEQLTKIEPGELYNGT 299 Query: 157 RLVLTPRETPQSITVVTRQNMDDFGLNNIDDVMRHTPGITVSAYDTDRNNYYARG--FSI 214 ++ + + + + I+D + + + N +Y R F Sbjct: 300 KVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT---VKLRVNVDAGNRFYVRKIRFEG 356 Query: 215 NNFQYDGIPS----TARNVGYSAGNTLSDMAIYDRV---EVLKGATGLLTGAGSLGATIN 267 N+ D + + +R+ E + T + G+ + Sbjct: 357 NDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVY 416 Query: 268 LIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSF------ 321 ++++ T F + G S ++++ + L D ++ Sbjct: 417 KVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTG--YAVGINGTKNDYQTYAELSVT 474 Query: 322 -----MDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRN 376 +D ++Y + D + T N G+ + FP+ + R Sbjct: 475 NPYFTVDGVSLGGRLFYNDFQADDADLSDYT-------NKSYGTDVTLGFPINEYNSLRA 527 Query: 377 DVSRSFNNGAKWSSWEQYTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPA 436 + N+ + R +++ EH + + D Y + + Sbjct: 528 GLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFNYGWTYNKLDRGYFP 587 Query: 437 PDNSAKIVAQKYTGE-TKSNSLDIYL-TGPFQFLGREHELVVGTSASFSHWEGKSYWNLR 494 D S + K T + + + L T + + +H+ VV + + +G + Sbjct: 588 TDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDDHKWVVLGRTRWGYGDGLGGKEMP 647 Query: 495 NYDNTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYM---------TARFNVTDDLNL 545 Y+N + G + Y Q +Y + Sbjct: 648 FYENFYAGGSSTVRGFQSNTIGPKAVYFP---HQASNYDPDYDYECATQDGAKDLCKSDD 704 Query: 546 FLGGR---VVDYRVTGLNPTIRES------GRFIPYVGAVYDLNDTYSVYASYTDIFMPQ 596 +GG V P I + F +G V+D N S Y+ Y D P Sbjct: 705 AVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPS 764 Query: 597 D 597 + Sbjct: 765 N 765 >3RQ4-A nrPDB Length = 247 Score = 34.5 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 47/138 (34%), Gaps = 28/138 (20%) Query: 31 MALSLPLAGYVQAQEVEFDIPP-------QALGSALQEFGRQADIQVLYRPEEVRN---- 79 +A SL L Y+ + + ++ P Q L SAL+ F RQ D++ YR + Sbjct: 16 LATSLVLDPYLGFRTHKMNVSPVPPLRRQQHLRSALETFLRQRDLEAAYRALTLGGWTAR 75 Query: 80 -------KRSSAIKGKLE-------PNQAITELLRGTGASVDFQGNAITISVAEAADSSV 125 ++ +A+K + P T L + N I A + Sbjct: 76 YFQSRGPRQEAALKTHVYRYLRAFLPESGFTIL---PCTRYSMETNGAKIVSTRAWKKNE 132 Query: 126 DLGATMITSNQLGTITED 143 L + +L E Sbjct: 133 KLELLVGCIAELREADEG 150 >4AU7-A nrPDB Length = 247 Score = 34.1 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 42/123 (34%), Gaps = 22/123 (17%) Query: 31 MALSLPLAGYVQAQEVEFDIPPQA-------LGSALQEFGRQADIQVLYRPEEVRNKRSS 83 +A SL L Y+ + + ++ P L SAL+ F RQ D++ +R + + Sbjct: 18 LATSLVLDPYLGFRTHKMNVSPVPTLRRQHHLRSALEAFLRQRDLEAAFRALTLGGWMAH 77 Query: 84 AIKGKLEPNQA---------ITELLRGTG------ASVDFQGNAITISVAEAADSSVDLG 128 + + +A + L +G + N I A + L Sbjct: 78 YFQSRAPRQEAALKTHIFCYLRAFLPESGFTILPCTRYSMETNGAKIVSTRAWKKNEKLE 137 Query: 129 ATM 131 + Sbjct: 138 LLV 140 >3SQR-A nrPDB Length = 580 Score = 32.9 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 30/209 (14%), Positives = 58/209 (27%), Gaps = 18/209 (8%) Query: 576 VYDLNDTYSVYASYTDIFMPQDSWYRDSSNKLLEPDEGQNYEI----GIKGEYLDGRLNT 631 ++D + A + +++ +S G+ +E+ G K + Sbjct: 213 IWDTARLGAPPALENTLMNGTNTFDCSASTDPNCVGGGKKFELTFVEGTKYRLRLINVGI 272 Query: 632 SLAYFEIHEENRAEEDALYNSKPTNPAITYAYKGIKAKTKGYEAEISGELAPGWQVQAGY 691 ++FE +N + P P T + E + W Sbjct: 273 D-SHFEFAIDNHTLTVIANDLVPIVPYTTDTLLIGIGQRYDVIVEANAAADNYW------ 325 Query: 692 THKIIRDDSGKKVSTWEPQDQLSLYTSYKFKGALDKLTVGGGARWQGKSWQMVYNNPRSR 751 IR + G ST + Y + +VG R + + Sbjct: 326 ----IRGNWGTTCSTNNEAANATGILRYDSSSIANPTSVGTTPRGTCEDEPVA---SLVP 378 Query: 752 WEKFSQEDYWLVDLMARYQITDKLSASVN 780 Y LVD T+ + ++N Sbjct: 379 HLALDVGGYSLVDEQVSSAFTNYFTWTIN 407 >3ZTV-A nrPDB Length = 579 Score = 32.5 bits (72), Expect = 0.66, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 25/69 (36%), Gaps = 1/69 (1%) Query: 254 GLLTGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAV- 312 G++TG+ G + N I K +G + + Y V + +G VR + Sbjct: 359 GVITGSAMPGGSANRIPNKAGSNPEGSIATRFIAETMYNELKTVDLTIQNAGGVRADILP 418 Query: 313 AAYQDKHSF 321 ++ Sbjct: 419 GNVTFNDAY 427 >4G2C-A nrPDB Length = 493 Score = 32.2 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 24/88 (27%), Gaps = 11/88 (12%) Query: 498 NTTDDFINWDGDIGKPDWGTPSQYIDDKTRQLGSYMTAR--------FNVTD-DLNLFLG 548 +TTD +WD P D T GSY R F + DL LG Sbjct: 236 DTTDGVNDWDPSAPLEQVLVPDPAAPDPTVHFGSYFVFRKLEQNVRLFKEAERDLAHDLG 295 Query: 549 GRVVDYRVTGL--NPTIRESGRFIPYVG 574 R D G + Sbjct: 296 LRGEDRERAGAMLVGRFEDGTPLTAQSA 323 >1W3H-A nrPDB Length = 359 Score = 32.2 bits (71), Expect = 0.92, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 36/106 (33%), Gaps = 5/106 (4%) Query: 477 GTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIGKPDWGTPSQYIDDK-----TRQLGS 531 G++ SF++ + W +N + W P+W + S + + + Sbjct: 66 GSNFSFTNSDRLVSWAAQNGQTVHGHTLVWHPSYQLPNWASDSNANFRQDFARHIDTVAA 125 Query: 532 YMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGRFIPYVGAVY 577 + + D +N L D G R+S + + G Y Sbjct: 126 HFAGQVKSWDVVNEALFDSADDPDGRGSANGYRQSVFYRQFGGPEY 171 >6D6Q-B nrPDB Length = 249 Score = 32.2 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 17/55 (30%), Positives = 27/55 (49%) Query: 38 AGYVQAQEVEFDIPPQALGSALQEFGRQADIQVLYRPEEVRNKRSSAIKGKLEPN 92 AG ++ + + QA GSA E G + V+Y P E+R R+ A+ + N Sbjct: 23 AGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVN 77 >6FSU-A nrPDB Length = 420 Score = 32.2 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 50/341 (14%), Positives = 100/341 (29%), Gaps = 25/341 (7%) Query: 274 THEFKGHVELGAGSWDNYRSELDVSGPLTESGNVRGRAVAAYQDKHSFMDHYERKTSVYY 333 E + G + + V G + + A + + + +D ++Y Sbjct: 34 GTESGVSFQAGVQQDNWLGTGYAV-GINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFY 92 Query: 334 GILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQGNRNDVSRSFNNGAKWSSWEQ 393 + D + T N G+ + FP+ + R + N+ + Sbjct: 93 NDFQADDADLSDYT-------NKSYGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVA 145 Query: 394 YTRTVFANLEHNFANGWVGKVQLDHKINGYHAPLGAIMGDWPAPDNSAKIVAQKYTGE-T 452 R +++ EH + + D Y + + D S + K T + Sbjct: 146 MWRYLYSMGEHPSTSDQDNSFKTDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGS 205 Query: 453 KSNSLDIYL-TGPFQFLGREHELVVGTSASFSHWEGKSYWNLRNYDNTTDDFINWDGDIG 511 + + L T + + +H+ VV + + +G + Y+N + Sbjct: 206 DNEYYKVTLDTATYVPIDDDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQ 265 Query: 512 KPDWGTPSQYIDDKTRQLG------SYMTARFNVTDDLNLFLGGR---VVDYRVTGLNPT 562 G + Y + S + +GG V P Sbjct: 266 SNTIGPKAVYFPHQASNYDPDYDYESATQDGAKDLSKSDDAVGGNAMAVASLEFITPTPF 325 Query: 563 IRES------GRFIPYVGAVYDLNDTYSVYASYTDIFMPQD 597 I + F +G V+D N S Y+ Y D P + Sbjct: 326 ISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSN 366 >5EW5-A nrPDB Length = 582 Score = 31.0 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 23/137 (16%), Positives = 47/137 (34%), Gaps = 14/137 (10%) Query: 109 QGNAITISVAEAADSSVDLGATMITSNQLGTITEDSGSYTPGTIATATRLVLTPRETPQS 168 N ++ V D+ + ++S L T + + + + P S Sbjct: 149 DPNMMSKIVTSLPAD--DITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMS 206 Query: 169 ITVVTRQNMDDFGLNNID---------DVMRHTPGI-TVSAYDTDRNNYYAR--GFSINN 216 + VV + + G+ V TP + T+S T+ + R GF+ Sbjct: 207 VPVVDAKPTERPGVFTASIPGAPVLNISVNDSTPAVQTLSPGVTNNTDKDVRPAGFTQGG 266 Query: 217 FQYDGIPSTARNVGYSA 233 D + ++ G++A Sbjct: 267 NTRDAVIRFPKDSGHNA 283 >3AK5-A nrPDB Length = 975 Score = 30.2 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 54/329 (16%), Positives = 101/329 (30%), Gaps = 12/329 (3%) Query: 82 SSAIKGKLEPNQAITELLRGTGASVDFQGNAITISVAEAADSSVDLGATMITSNQLGTIT 141 ++ I G L+G + ++ +A + D SV T + + Sbjct: 516 AADISGTFTQENG-RLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRS 574 Query: 142 EDSGSYTPGTIATATRLVLTPRETPQ--SITVV---TRQNMDDFGLNNIDDVMRHTPGIT 196 + T T Q + +V +R +D + + Sbjct: 575 FTFDRLSLKNTDFGLGRNATLNTTIQADNSSVTLGDSRVFIDKNDGQGTAFTLEEGTSVA 634 Query: 197 VSAYDTDRNNYYARGFSINNFQYDGIPSTARNVGYSAGNTLSDMAIYDRVEVLKGATGLL 256 D N + + + I + S N SD A+ + A L Sbjct: 635 TKDADKSVFNGTVNLDNQSVLNINDIFNGGIQANNSTVNISSDSAVLGNSTLTSTALNLN 694 Query: 257 TGAGSLGATINLIRKKPTHEFKGHVELGAGSWDNYRS---ELDVSGPLTESGNVRGRAVA 313 GA +L A+ + + P + + L + + + D +G G+ V Sbjct: 695 KGANAL-ASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSWNLKGDDARLNVG 753 Query: 314 AYQDKHSFMDHYERKTSVYYGILEFDLNPDTMLTVGADYQDNDPKGSGWSGSFPLFDSQG 373 Y ++ ++ T G E +L+PD L Y + + WSGS D+ Sbjct: 754 PYSMLSGNINVQDKGTVTLGG--EGELSPDLTLQNQMLYSLFNGYRNIWSGSLNAPDATV 811 Query: 374 NRNDVSRSFNNGAKWSSWEQYTRTVFANL 402 + D S N + + + V N Sbjct: 812 SMTDTQWSMNGNSTAGNMKLNRTIVGFNG 840 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.302 0.117 0.272 Lambda K H 0.267 0.0358 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,741,658 Number of Sequences: 36641 Number of extensions: 1013288 Number of successful extensions: 3043 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 61 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 2729 Number of HSP's gapped (non-prelim): 126 length of query: 815 length of database: 10,336,785 effective HSP length: 105 effective length of query: 710 effective length of database: 6,489,480 effective search space: 4607530800 effective search space used: 4607530800 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 63 (29.1 bits)