BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P48491 (254 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4OBT-A nrPDB 513 e-146 6CG9-A nrPDB 427 e-120 6NEE-A nrPDB 345 9e-96 4OHQ-A nrPDB 317 2e-87 4POC-A nrPDB 305 1e-83 1SW7-A nrPDB 301 1e-82 2I9E-A nrPDB 297 3e-81 3TH6-A nrPDB 282 8e-77 5ZGA-A nrPDB 281 2e-76 4MKN-A nrPDB 281 2e-76 5EYW-A nrPDB 271 2e-73 1MO0-A nrPDB 270 4e-73 2VXN-A nrPDB 265 1e-71 1I45-A nrPDB 263 5e-71 1M6J-A nrPDB 253 5e-68 5UPR-A nrPDB 253 5e-68 5CG7-A nrPDB 253 7e-68 1CI1-A nrPDB 248 1e-66 3KRS-A nrPDB 242 1e-64 1LZO-A nrPDB 241 2e-64 3Q37-A nrPDB 239 7e-64 3PF3-A nrPDB 238 3e-63 1KV5-A nrPDB 230 4e-61 5VWN-A nrPDB 228 1e-60 2V5B-A nrPDB 224 2e-59 1TMH-A nrPDB 212 1e-55 1TRI-A nrPDB 210 5e-55 2Y70-A nrPDB 209 7e-55 1B9B-A nrPDB 200 4e-52 4Y96-A nrPDB 194 3e-50 1BTM-A nrPDB 180 6e-46 3UWW-A nrPDB 179 1e-45 4Y8F-A nrPDB 177 3e-45 5IBX-C nrPDB 175 2e-44 4X22-A nrPDB 174 2e-44 5UJW-A nrPDB 171 2e-43 1AW2-A nrPDB 170 6e-43 4G1K-A nrPDB 166 1e-41 1YYA-A nrPDB 166 1e-41 4Y9A-A nrPDB 163 6e-41 3TA6-A nrPDB 162 1e-40 3KXQ-A nrPDB 152 1e-37 4NVT-A nrPDB 149 1e-36 6BVE-A nrPDB 149 2e-36 4Y90-A nrPDB 138 3e-33 2JGQ-A nrPDB 132 2e-31 3S6D-A nrPDB 86 2e-17 5CSS-A nrPDB 47 9e-06 1W0M-A nrPDB 43 2e-04 1HG3-A nrPDB 35 0.028 2H6R-A nrPDB 34 0.048 5X3F-A nrPDB 30 0.93 3PIH-A nrPDB 30 1.3 5CED-A nrPDB 29 1.6 4IVN-A nrPDB 29 2.3 4NEF-A nrPDB 28 4.2 4OJ2-X nrPDB 28 5.5 1Z1W-A nrPDB 27 6.7 >4OBT-A nrPDB Length = 257 Score = 513 bits (1321), Expect = e-146, Method: Compositional matrix adjust. Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF Sbjct: 4 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 63 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ Sbjct: 64 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 123 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA Sbjct: 124 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 183 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE Sbjct: 184 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 243 Query: 241 FIDIIKAAEVKKSA 254 FIDIIKAAEVKKSA Sbjct: 244 FIDIIKAAEVKKSA 257 >6CG9-A nrPDB Length = 256 Score = 427 bits (1098), Expect = e-120, Method: Compositional matrix adjust. Identities = 205/253 (81%), Positives = 224/253 (88%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 M RKFFVGGNWKCNGT ++V+KIV TLNE QVP DVVEVVVSPPYVFLP+VKS LR +F Sbjct: 4 MGRKFFVGGNWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQEF 63 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 VAAQNCWVKKGGAFTGEVSAEMLVNL +PWVILGHSERRA+L ES+EFVGDKVAYAL+Q Sbjct: 64 HVAAQNCWVKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALSQ 123 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GLKVIACVGETLE+REAGSTMDVVAAQTKAIA+++ +WSNVV+AYEPVWAIGTGKVA+PA Sbjct: 124 GLKVIACVGETLEQREAGSTMDVVAAQTKAIAEKIKDWSNVVVAYEPVWAIGTGKVATPA 183 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVH LR WL N S +VA +TRIIYGGSV NCKEL Q DVDGFLVGGASLKPE Sbjct: 184 QAQEVHASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKPE 243 Query: 241 FIDIIKAAEVKKS 253 FIDII AA VK + Sbjct: 244 FIDIINAATVKSA 256 >6NEE-A nrPDB Length = 252 Score = 345 bits (885), Expect = 9e-96, Method: Compositional matrix adjust. Identities = 171/252 (67%), Positives = 199/252 (78%), Gaps = 6/252 (2%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS--D 59 +RKFFVGGNWK NGT E +K +V TLN AQ+ EVVV+PP ++LP +S L+ + Sbjct: 3 SRKFFVGGNWKMNGTLESIKALVETLNSAQLDPN--TEVVVAPPAIYLPFARSKLKKPKE 60 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 VAAQNC+ K GAFTGE+SAEML +L +PWVILGHSERR I ES E + +KV YAL Sbjct: 61 IQVAAQNCYTKPNGAFTGEISAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALD 120 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQT-KAIADRVTNWSNVVIAYEPVWAIGTGKVAS 178 QGLKVIAC+GETLEEREAG TM+VVA Q KAIAD++ +WSNVVIAYEPVWAIGTGKVA+ Sbjct: 121 QGLKVIACIGETLEEREAGKTMEVVARQILKAIADKIKDWSNVVIAYEPVWAIGTGKVAT 180 Query: 179 PAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK 238 P QAQEVH LRKWL +NVS +VA +TRIIYGGSVN NCKEL Q D+DGFLVGGASLK Sbjct: 181 PEQAQEVHAALRKWLKENVSPEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLK 240 Query: 239 -PEFIDIIKAAE 249 PEF+DII A + Sbjct: 241 APEFVDIINARQ 252 >4OHQ-A nrPDB Length = 256 Score = 317 bits (813), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 157/252 (62%), Positives = 189/252 (75%), Gaps = 3/252 (1%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVA 63 KFFVGGNWKCNGT + + K+++ LN A + + V+VVVSPP+V++ VKS+L ++ Sbjct: 6 KFFVGGNWKCNGTKDSIAKLISDLNSATLEAD--VDVVVSPPFVYIDQVKSSLTDRIDIS 63 Query: 64 AQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLK 123 QN WV KGGAFTGE+S E L +L WVILGHSERR ++ E EF+G K AYAL++GL Sbjct: 64 GQNSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLG 123 Query: 124 VIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQ 183 VIAC+GE LEEREAG T DV AQ KA AD V +W N+V+AYEPVWAIGTGKVASP QAQ Sbjct: 124 VIACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAYEPVWAIGTGKVASPQQAQ 183 Query: 184 EVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEFI 242 EVH +R WL KNVS +VA+ TRIIYGGSVNGGN EL + D+DGFLVGGASLK PEF Sbjct: 184 EVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEFA 243 Query: 243 DIIKAAEVKKSA 254 I+ + KK A Sbjct: 244 TIVNSVTSKKVA 255 >4POC-A nrPDB Length = 254 Score = 305 bits (782), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 149/248 (60%), Positives = 180/248 (72%), Gaps = 2/248 (0%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 +RKFFVGGNWK NG + + +++ TLN A+VP+ EVV +PP ++ + L Sbjct: 9 SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPAD--TEVVCAPPTAYIDFARQKLDPKIA 66 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 VAAQNC+ GAFTGE+S M+ + WV+LGHSERR + ES E +G KVA+ALA+G Sbjct: 67 VAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEG 126 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L VIAC+GE L+EREAG T VV QTK IAD V +WS VV+AYEPVWAIGTGK A+P Q Sbjct: 127 LGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQ 186 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEF 241 AQEVH++LR WL NVS VA +TRIIYGGSV G CKEL Q DVDGFLVGGASLKPEF Sbjct: 187 AQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEF 246 Query: 242 IDIIKAAE 249 +DII A + Sbjct: 247 VDIINAKQ 254 >1SW7-A nrPDB Length = 248 Score = 301 bits (772), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 148/245 (60%), Positives = 181/245 (73%), Gaps = 2/245 (0%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 RKFFVGGNWK NG + + ++++TLN A++ + EVV P ++L + L + V Sbjct: 4 RKFFVGGNWKMNGDKKSLGELIHTLNGAKLSAD--TEVVCGAPSIYLDFARQKLDAKIGV 61 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQNC+ GAFTGE+S M+ ++ WVILGHSERR + ES E +G KVA+ALA+GL Sbjct: 62 AAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGL 121 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 VIAC+GE L+EREAG T VV QTKAIAD V +WS VV+AYEPVWAIGTG ++P QA Sbjct: 122 GVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGNSSTPQQA 181 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH++LR WL +VS VA +TRIIYGGSV GGNCKEL Q DVDGFLVGGASLKPEF+ Sbjct: 182 QEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEFV 241 Query: 243 DIIKA 247 DII A Sbjct: 242 DIINA 246 >2I9E-A nrPDB Length = 259 Score = 297 bits (761), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 146/250 (58%), Positives = 180/250 (72%), Gaps = 2/250 (0%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 MARKF VGGNWK NG +++ +I+ L P EVVV P ++L LV++ + + Sbjct: 1 MARKFVVGGNWKMNGDKKQINEIIGFLKSG--PLNQDTEVVVGVPAIYLELVRTCVPASI 58 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 VAAQNC+ GAFTGE+S M+ ++ WVILGHSERR I ES E + +KV +AL Sbjct: 59 GVAAQNCYKVPKGAFTGEISPAMIKDVGADWVILGHSERRQIFGESDELIAEKVCHALES 118 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GLKVIAC+GETLEEREAG T +VV QTKAIA +V +WSNVVIAYEPVWAIGTGK A+P Sbjct: 119 GLKVIACIGETLEEREAGKTEEVVFRQTKAIAAKVNDWSNVVIAYEPVWAIGTGKTATPQ 178 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQ+VH LR+W+ +N+ A V + RI YGGSV NCKEL Q D+DGFLVGGASLKPE Sbjct: 179 QAQDVHKALRQWICENIDAKVGNSIRIQYGGSVTAANCKELASQPDIDGFLVGGASLKPE 238 Query: 241 FIDIIKAAEV 250 F+DII A ++ Sbjct: 239 FVDIINARQL 248 >3TH6-A nrPDB Length = 249 Score = 282 bits (722), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 140/248 (56%), Positives = 174/248 (70%), Gaps = 2/248 (0%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 AR+F VGGNWK +G+ ++ I NTL A + VEV+V+ P +L +S L Sbjct: 3 ARRFCVGGNWKMHGSKNSIRDICNTLKGASLDPN--VEVIVACPAPYLDYCRSLLPPSVA 60 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 +AAQNC+ + GAFTGE+S M+ + WVILGHSERR + E +G+K+ +AL G Sbjct: 61 LAAQNCYKVEQGAFTGEISPGMIKDCGGQWVILGHSERRHVFKEDDVLIGEKIKHALESG 120 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L VIAC+GE LE+REAG T +V Q K IA V +WS VVIAYEPVWAIGTGK A+P Q Sbjct: 121 LNVIACIGELLEDREAGRTEEVCFRQIKHIASNVKDWSKVVIAYEPVWAIGTGKTATPDQ 180 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEF 241 AQEVH ++R WL+ NVSADVA+ RI YGGSVN GNCKELG + D+DGFLVGGASLKPEF Sbjct: 181 AQEVHSKVRNWLSTNVSADVASKVRIQYGGSVNAGNCKELGRKPDIDGFLVGGASLKPEF 240 Query: 242 IDIIKAAE 249 + II A + Sbjct: 241 VQIINAMQ 248 >5ZGA-A nrPDB Length = 269 Score = 281 bits (720), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 137/245 (55%), Positives = 175/245 (71%), Gaps = 2/245 (0%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 RKFFVGGNWK NG+ +E K++ L A++ EV+V+PP ++LP V+ L F V Sbjct: 25 RKFFVGGNWKMNGSKKENDKLIEMLTHAKIDPN--TEVLVAPPALYLPSVREKLDKRFHV 82 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQNC+ GAFTGEVS ML ++ WVILGHSERR IL E+ + VG+K A+A++ G+ Sbjct: 83 AAQNCYKVPSGAFTGEVSPAMLKDVGCDWVILGHSERRHILLETDQLVGEKTAHAISAGV 142 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 VIAC+GE LEEREAG T +V Q +AI ++ W+++VIAYEPVWAIGTGK A+ QA Sbjct: 143 NVIACIGEKLEEREAGKTEEVCFRQMEAIRKNLSMWNHIVIAYEPVWAIGTGKTATEQQA 202 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH +R+W+ + VS VA + RIIYGGSV NC+ L Q DVDGFLVGGASLKP+FI Sbjct: 203 QEVHLAVRRWMEEKVSPAVAKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASLKPDFI 262 Query: 243 DIIKA 247 +I A Sbjct: 263 EICNA 267 >4MKN-A nrPDB Length = 270 Score = 281 bits (719), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 142/250 (56%), Positives = 178/250 (71%), Gaps = 4/250 (1%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFV 62 KFFVGGNWKCNG+ V K+V+ LN +P V+VVV+PP++++ V L R + + Sbjct: 20 KFFVGGNWKCNGSVANVAKLVDELNAGTIPRG--VDVVVAPPFIYIDYVMQHLDRDKYQL 77 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 +AQN W+ GAFTGEVSAE L + +PWVILGHSERR++ ES+E V K ++ALA GL Sbjct: 78 SAQNAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAAGL 137 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 VIAC+GETLE+R +GS V+ AQ A+ D V +W+ VV+AYEPVWAIGTG VASP QA Sbjct: 138 GVIACIGETLEQRNSGSVFKVLDAQMDALVDEVKDWTKVVLAYEPVWAIGTGVVASPEQA 197 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEF 241 QEVH LR++ AK + A VA RIIYGGSV+ NCK+L Q D+DGFLVGGASLK F Sbjct: 198 QEVHAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGAAF 257 Query: 242 IDIIKAAEVK 251 + I AA K Sbjct: 258 VTICNAAGPK 267 >5EYW-A nrPDB Length = 249 Score = 271 bits (694), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 131/245 (53%), Positives = 170/245 (69%), Gaps = 2/245 (0%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 RKFFVGGNWK NG + I++ + P EVVV P +L + + ++ + Sbjct: 5 RKFFVGGNWKMNGDKAAIDGIISFMKTG--PLSPNTEVVVGCPQCYLMYTREHMPANIGI 62 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQNC+ GAFTGE+S M+ + WVILGHSERR + E + + +KV +AL GL Sbjct: 63 AAQNCYKVAKGAFTGEISPAMVKDCGCEWVILGHSERRNVFGEPDQLISEKVGHALEAGL 122 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 KVI C+GE LE+RE T +VV AQ KA+ +++WS VV+AYEPVWAIGTGK ASP QA Sbjct: 123 KVIPCIGEKLEDREGNRTQEVVFAQMKALLPNISDWSRVVLAYEPVWAIGTGKTASPEQA 182 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH +LR+WL NV+A+VA +TRIIYGGSV+ GNC+EL + D+DGFLVGGA+LKP+F+ Sbjct: 183 QEVHADLRQWLRDNVNAEVAESTRIIYGGSVSAGNCQELAKKGDIDGFLVGGAALKPDFV 242 Query: 243 DIIKA 247 II A Sbjct: 243 QIINA 247 >1MO0-A nrPDB Length = 275 Score = 270 bits (690), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 138/247 (55%), Positives = 169/247 (68%), Gaps = 2/247 (0%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 + RKFFVGGNWK NG V IV LN + S V+VVV+PP +L KS L++ Sbjct: 21 LTRKFFVGGNWKMNGDYASVDGIVTFLNASADNSS--VDVVVAPPAPYLAYAKSKLKAGV 78 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 VAAQNC+ GAFTGE+S M+ +L + WVILGHSERR + ES + +K +AL Sbjct: 79 LVAAQNCYKVPKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHALEA 138 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 G+KV+ C+GE LEEREAG T DV Q +AI D+ +W N+VIAYEPVWAIGTGK AS Sbjct: 139 GIKVVFCIGEKLEEREAGHTKDVNFRQLQAIVDKGVSWENIVIAYEPVWAIGTGKTASGE 198 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVH+ +R +L + VS VA TRIIYGGSV N ELG + D+DGFLVGGASLKP+ Sbjct: 199 QAQEVHEWIRAFLKEKVSPAVADATRIIYGGSVTADNAAELGKKPDIDGFLVGGASLKPD 258 Query: 241 FIDIIKA 247 F+ II A Sbjct: 259 FVKIINA 265 >2VXN-A nrPDB Length = 251 Score = 265 bits (678), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 135/243 (55%), Positives = 173/243 (71%), Gaps = 6/243 (2%) Query: 8 GGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFFVAAQN 66 NWKCNGT ++K+V NE + S DV + VV+P +V +PLV++ LR+ + ++AQN Sbjct: 10 AANWKCNGTTASIEKLVQVFNEHTI-SHDV-QCVVAPTFVHIPLVQAKLRNPKYVISAQN 67 Query: 67 CWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIA 126 + K GAFTGEVS +L ++ + WVILGHSERR E+ E V KV+ A QG VIA Sbjct: 68 A-IAKSGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGFMVIA 126 Query: 127 CVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPAQAQE 184 C+GETL++REA T VV +QT AIA ++T W+ VV+AYEPVWAIGTGKVA+P QAQE Sbjct: 127 CIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKVATPEQAQE 186 Query: 185 VHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDI 244 VH LRKW+++N+ DVAA RI+YGGSVN N L + D++GFLVGGASLKPEF DI Sbjct: 187 VHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPEFRDI 246 Query: 245 IKA 247 I A Sbjct: 247 IDA 249 >1I45-A nrPDB Length = 248 Score = 263 bits (672), Expect = 5e-71, Method: Compositional matrix adjust. Identities = 127/248 (51%), Positives = 171/248 (68%), Gaps = 3/248 (1%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-D 59 MAR FFVGGN+K NG+ + +K+IV LN A +P VEVV+ PP +L S ++ Sbjct: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPEN--VEVVICPPATYLDYSVSLVKKPQ 58 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 V AQN ++K GAFTGE S + + ++ +VILGHSERR+ +E +F+ DK +AL Sbjct: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKYVILGHSERRSYFHEDDKFIADKTKFALG 118 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASP 179 QG+ VI C+GETLEE++AG T+DVV Q A+ + V +++NVV+AYEPVWAIGTG A+P Sbjct: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDFTNVVVAYEPVWAIGTGLAATP 178 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 AQ++H +RK+LA + A+ RI+YGGS NG N +ADVDGFLVGGASLKP Sbjct: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 Query: 240 EFIDIIKA 247 EF+DII + Sbjct: 239 EFVDIINS 246 >1M6J-A nrPDB Length = 261 Score = 253 bits (646), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 132/248 (53%), Positives = 170/248 (68%), Gaps = 17/248 (6%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDV-----VEVVVSPPYVFLPLVKSTL 56 A KF VGGNWKCNGT ++ TL + S D VEV+V P++++P V+ L Sbjct: 3 AGKFVVGGNWKCNGTLASIE----TLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQIL 58 Query: 57 R-----SDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVG 111 ++ V+A+N W K G A+TGEV MLV+ +P+VILGHSERR I +ES+E V Sbjct: 59 AGEANGANILVSAENAWTKSG-AYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVA 117 Query: 112 DKVAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVW 169 +KV A+ GLKVIAC+GET +R A T +VVAAQ KAI + ++ W N+++AYEPVW Sbjct: 118 EKVKVAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVW 177 Query: 170 AIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDG 229 AIGTGK A+P QAQEVH +RKW+ +N+S +VA TRI YGGSVN NC EL +AD+DG Sbjct: 178 AIGTGKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDG 237 Query: 230 FLVGGASL 237 FLVGGASL Sbjct: 238 FLVGGASL 245 >5UPR-A nrPDB Length = 265 Score = 253 bits (646), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 138/257 (53%), Positives = 178/257 (69%), Gaps = 10/257 (3%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 AR+ FVGGNWKCNGT + +++V+ LN A V S + V+VVV+PP +F+ V+ +LR Sbjct: 7 ARRGFVGGNWKCNGTTAKTQELVDMLNSAPV-SFEQVDVVVAPPSLFISQVQDSLRQPRV 65 Query: 62 -VAAQNCWVKKG-GAFTGEVSAEMLVNLDIPWVILGHSERRAILN----ESSEFVGDKVA 115 VAAQ+ ++ GAFTGE+S +M+ +IPWV+LGHSERRA ES++ V KV Sbjct: 66 QVAAQDSSTQQAYGAFTGELSPKMIKEKNIPWVVLGHSERRAGFGGQPGESNQVVAKKVR 125 Query: 116 YALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN---WSNVVIAYEPVWAIG 172 AL +GL VI C+GETLEERE+G T V++ Q +A+ V W ++VIAYEPVWAIG Sbjct: 126 AALNEGLSVILCIGETLEERESGQTQKVLSEQLEAVRQAVPEADAWKSIVIAYEPVWAIG 185 Query: 173 TGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLV 232 TGK A+ A AQE H ++R WLA+ VS VA TR+IYGGSV G N KEL DVDGFLV Sbjct: 186 TGKTATAALAQETHRDIRNWLAQAVSPKVAEATRVIYGGSVKGSNAKELFEGEDVDGFLV 245 Query: 233 GGASLKPEFIDIIKAAE 249 GGASL +F+ II AA+ Sbjct: 246 GGASLTGDFVSIIDAAK 262 >5CG7-A nrPDB Length = 271 Score = 253 bits (645), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 131/245 (53%), Positives = 168/245 (68%), Gaps = 6/245 (2%) Query: 6 FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFVAA 64 V NWKCNGT ++K+V LNE Q+ V+ VV+P +V +P+V++ L + V+A Sbjct: 28 IVAANWKCNGTTASIEKLVQVLNEHQIDHD--VQCVVAPSFVHIPMVQAKLCNPKYAVSA 85 Query: 65 QNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKV 124 +N + K GAFTGEVS +L +L + WVILGHSERR E+ V KVA A QG V Sbjct: 86 ENA-IAKSGAFTGEVSMPILKDLGVSWVILGHSERRTYYGETDGVVAQKVADAYNQGFMV 144 Query: 125 IACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPAQA 182 IAC+GETL++REA T VV +QT AIA ++ WS +V+AYEPVWAIGTGKVA+P QA Sbjct: 145 IACIGETLQQREANQTAKVVLSQTAAIAAKLPKEAWSQIVLAYEPVWAIGTGKVATPEQA 204 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH LR+W+++ + VA RI+YGGSV GN K L + D++GFLVGGASLKPEF Sbjct: 205 QEVHALLRQWVSEKIGNGVATKLRILYGGSVTAGNAKTLYMKPDINGFLVGGASLKPEFR 264 Query: 243 DIIKA 247 DII A Sbjct: 265 DIIDA 269 >1CI1-A nrPDB Length = 251 Score = 248 bits (634), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 127/245 (51%), Positives = 167/245 (68%), Gaps = 6/245 (2%) Query: 8 GGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFFVAAQN 66 NWKCNG+ + ++ TLN A V+ VV+P ++ +P+ K+ L + F +AAQN Sbjct: 10 AANWKCNGSESLLVPLIETLNAATFDHD--VQCVVAPTFLHIPMTKARLTNPKFQIAAQN 67 Query: 67 CWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIA 126 + + GAFTGEVS ++L + I WV+LGHSERR E++E V +KVA A A G VI Sbjct: 68 A-ITRSGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGFHVIV 126 Query: 127 CVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPAQAQE 184 CVGET EEREAG T VV Q A+A +++ WS VVIAYEPVWAIGTGKVA+P QAQE Sbjct: 127 CVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQQAQE 186 Query: 185 VHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDI 244 VH+ LR+W+ + D+AA RI+YGGSV N + L D++GFLVGGASLKPEF++I Sbjct: 187 VHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEFVEI 246 Query: 245 IKAAE 249 I+A + Sbjct: 247 IEATK 251 >3KRS-A nrPDB Length = 271 Score = 242 bits (618), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 122/254 (48%), Positives = 171/254 (67%), Gaps = 9/254 (3%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD- 59 M+RK+FVGGN+KCNGT E +K ++++ + + + EV V P + + LVK +D Sbjct: 22 MSRKYFVGGNFKCNGTKESLKTLIDSFKQVESSNS---EVYVFPTSLHISLVKEFFGNDH 78 Query: 60 ---FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAY 116 F + +QN GAFTGEVS EML ++D+ ++GHSERR +E+ + V +KV Sbjct: 79 PGVFKIGSQNISCTGNGAFTGEVSCEMLKDMDVDCSLVGHSERRQYYSETDQIVNNKVKK 138 Query: 117 ALAQGLKVIACVGETLEEREAGSTMDVVAAQ-TKAIADRVTNWSNVVIAYEPVWAIGTGK 175 L GLK++ C+GE+L ERE G T DV+ Q T+A+ D V++ SN+VIAYEP+WAIGTG Sbjct: 139 GLENGLKIVLCIGESLSERETGKTNDVIQKQLTEALKD-VSDLSNLVIAYEPIWAIGTGV 197 Query: 176 VASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA 235 VA+P QAQE H +R+++ + + V++ RIIYGGSV NC EL AD+DGFLVGGA Sbjct: 198 VATPGQAQEAHAFIREYVTRMYNPQVSSNLRIIYGGSVTPDNCNELIKCADIDGFLVGGA 257 Query: 236 SLKPEFIDIIKAAE 249 SLKP F II++A+ Sbjct: 258 SLKPTFAKIIESAQ 271 >1LZO-A nrPDB Length = 248 Score = 241 bits (615), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 119/249 (47%), Positives = 158/249 (63%), Gaps = 3/249 (1%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQV-PSQDVVEVVVSPPYVFLPLVKSTLRSD 59 MARK+FV NWKCNGT E +K + N+ N PS+ ++VVV P V + L+S Sbjct: 1 MARKYFVAANWKCNGTLESIKSLTNSFNNLDFDPSK--LDVVVFPVSVHYDHTRKLLQSK 58 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 F QN G++TGEVSAE+ +L+I +VI+GH ERR +E+ E V +K+ +L Sbjct: 59 FSTGIQNVSKFGNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLK 118 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASP 179 LK + C GE+LE+RE T++V+ Q KA D + N+ NV++ YEP+WAIGTGK A+P Sbjct: 119 NNLKAVVCFGESLEQREQNKTIEVITKQVKAFVDLIDNFDNVILVYEPLWAIGTGKTATP 178 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 QAQ VH E+RK + A RI+YGGSVN NC L Q D+DGFLVG ASLK Sbjct: 179 EQAQLVHKEIRKIVKDTCGEKQANQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASLKE 238 Query: 240 EFIDIIKAA 248 F+DIIK+A Sbjct: 239 SFVDIIKSA 247 >3Q37-A nrPDB Length = 251 Score = 239 bits (611), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 127/243 (52%), Positives = 172/243 (70%), Gaps = 6/243 (2%) Query: 10 NWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFFVAAQNCW 68 NWKCNG+ + + ++++ N + + DV + VV+P ++ +P+ K+ L + F +AAQN Sbjct: 12 NWKCNGSQQSLSELIDLFNSTSI-NHDV-QCVVAPTFLHIPMTKARLTNPKFQIAAQNA- 68 Query: 69 VKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACV 128 + + GAFTGEVS ++L + I WV+LGHSERRA E++E V DKVA A+A G VI CV Sbjct: 69 ITRSGAFTGEVSLQILKDYGISWVVLGHSERRAYYGETNEIVADKVAAAVASGFHVIVCV 128 Query: 129 GETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPAQAQEVH 186 GET EEREAG T VV Q A+A +++ WS VVIAYEPVWAIGTGKVA+P QAQEVH Sbjct: 129 GETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQQAQEVH 188 Query: 187 DELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDIIK 246 + LR+W+ + D+AA RI+YGGSV N + L D++GFLVGGASLKPEF++II+ Sbjct: 189 ELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEFVEIIE 248 Query: 247 AAE 249 A + Sbjct: 249 ATK 251 >3PF3-A nrPDB Length = 257 Score = 238 bits (606), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 123/249 (49%), Positives = 168/249 (67%), Gaps = 7/249 (2%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPL-VKSTLRSDF 60 AR+ F+GGN+KCNG+ + +K V + ++P D V+VV++P V L + + Sbjct: 3 ARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIP--DSVDVVIAPSAVHLSTAIAANTSKQL 60 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 +AAQN +++ GA+TGE S EML ++ + VI+GHSERR I+ E+ E K AL + Sbjct: 61 RIAAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEK 120 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN----WSNVVIAYEPVWAIGTGKV 176 G+ VI CVGETL+ER+A TM+V AQ +A+ + W VVIAYEPVW+IGTG V Sbjct: 121 GMTVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVV 180 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 A+P QA+EVH LRKW A+ V+A+ A RIIYGGS NG NC++LG ++DGFLVGGAS Sbjct: 181 ATPEQAEEVHVGLRKWFAEKVAAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGAS 240 Query: 237 LKPEFIDII 245 LKPEF+ +I Sbjct: 241 LKPEFMTMI 249 >1KV5-A nrPDB Length = 250 Score = 230 bits (587), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 129/243 (53%), Positives = 169/243 (69%), Gaps = 6/243 (2%) Query: 10 NWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFVAAQNCW 68 NWKCNG+ + + ++++ N + + DV + VV+ +V L + K L F +AAQN Sbjct: 11 NWKCNGSQQSLSELIDLFNSTSI-NHDV-QCVVASTFVHLAMTKERLSHPKFVIAAQNA- 67 Query: 69 VKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACV 128 + K GAFTGEVS +L + + W++LGHSERRA E++E V DKVA A+A G VIAC+ Sbjct: 68 IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIACI 127 Query: 129 GETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASPAQAQEVH 186 GETL+ERE+G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+P QAQE H Sbjct: 128 GETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEAH 187 Query: 187 DELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDIIK 246 + W++ + ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLKPEF+DIIK Sbjct: 188 ALISSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDIIK 247 Query: 247 AAE 249 A + Sbjct: 248 ATQ 250 >5VWN-A nrPDB Length = 246 Score = 228 bits (582), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 124/248 (50%), Positives = 158/248 (63%), Gaps = 11/248 (4%) Query: 3 RKFFVGGNWKCN-GTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 R FFVGGNWK N T +E +K+V LN A+V VEVVV+ P+VFLP ++ LR D+ Sbjct: 2 RTFFVGGNWKANPKTVQEAEKLVEMLNGAKVEGN--VEVVVAAPFVFLPTLQQKLRKDWK 59 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 V+A+N + K G + M+ + I W ILGHSERR IL E EF+ K +AL G Sbjct: 60 VSAENVFTKPNG------TVPMIKSFGIEWTILGHSERRDILKEDDEFLAAKAKFALENG 113 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASP 179 +K+I C GE L EREAG + V+AQ + + + W +VVIAYEP+WAIGTGKVAS Sbjct: 114 MKIIYCCGEHLSEREAGKASEFVSAQIEKMIPAIPAGKWDDVVIAYEPIWAIGTGKVAST 173 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 AQE+ +R LA V AD+A RI+YGGSV NC EL DVDGFLVGGASL+ Sbjct: 174 QDAQEMCKVIRDILAAKVGADIANKVRILYGGSVKPNNCNELAACPDVDGFLVGGASLEA 233 Query: 240 EFIDIIKA 247 FI+I+ + Sbjct: 234 GFINIVNS 241 >2V5B-A nrPDB Length = 244 Score = 224 bits (572), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 121/246 (49%), Positives = 157/246 (63%), Gaps = 15/246 (6%) Query: 8 GGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFFVAAQN 66 NWKCNG+ + ++ TLN A V+ VV+P ++ +P+ K+ L + F +AAQN Sbjct: 10 AANWKCNGSESLLVPLIETLNAATFDHD--VQCVVAPTFLHIPMTKARLTNPKFQIAAQN 67 Query: 67 CWVKKGGAFTGEVSA-EMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVI 125 G A L + I WV+LGHSERR E++E V +KVA A A G VI Sbjct: 68 A---------GNADALASLKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGFHVI 118 Query: 126 ACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPAQAQ 183 CVGET EEREAG T VV Q A+A +++ WS VVIAYEPVWAIGTGKVA+P QAQ Sbjct: 119 VCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGKVATPQQAQ 178 Query: 184 EVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFID 243 EVH+ LR+W+ + D+AA RI+YGGSV N + L D++GFLVGGASLKPEF++ Sbjct: 179 EVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEFVE 238 Query: 244 IIKAAE 249 II+A + Sbjct: 239 IIEATK 244 >1TMH-A nrPDB Length = 254 Score = 212 bits (540), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 120/255 (47%), Positives = 152/255 (59%), Gaps = 5/255 (1%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDFF 61 R V GNWK NG+ V ++V+ L + ++ V ++PP +++ + K S Sbjct: 2 RHPLVMGNWKLNGSRHMVHELVSNLRK-ELAGVAGCAVAIAPPEMYIDMAKREAEGSHIM 60 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQN + GAFTGE SA ML ++ ++I+GHSERR ES E + K A QG Sbjct: 61 LGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQG 120 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAI--ADRVTNWSNVVIAYEPVWAIGTGKVASP 179 L + C+GET E EAG T +V A Q A+ + VIAYEPVWAIGTGK A+P Sbjct: 121 LTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATP 180 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 AQAQ VH +R +AK V A++A I YGGSVN N EL Q DVDGFLVGGASLKP Sbjct: 181 AQAQAVHKFIRDHIAK-VDANIAEQVIIQYGGSVNASNAAELFAQHDVDGFLVGGASLKP 239 Query: 240 EFIDIIKAAEVKKSA 254 EF+DII AAE K A Sbjct: 240 EFVDIINAAEAAKQA 254 >1TRI-A nrPDB Length = 243 Score = 210 bits (534), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 122/244 (50%), Positives = 159/244 (65%), Gaps = 15/244 (6%) Query: 10 NWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFVAAQNCW 68 NWKCNG+ + + ++++ N + V+ VV+ +V L + K L F +AAQN Sbjct: 11 NWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKFVIAAQNA- 67 Query: 69 VKKGGAFTGEVSA-EMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIAC 127 G A L + + W++LGHSERRA E++E V DKVA A+A G VIAC Sbjct: 68 --------GNADALASLKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGFMVIAC 119 Query: 128 VGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASPAQAQEV 185 +GETL+ERE+G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+P QAQE Sbjct: 120 IGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQEA 179 Query: 186 HDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDII 245 H +R W++ + ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLKPEF+DII Sbjct: 180 HALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFVDII 239 Query: 246 KAAE 249 KA + Sbjct: 240 KATQ 243 >2Y70-A nrPDB Length = 245 Score = 209 bits (533), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 122/246 (49%), Positives = 156/246 (63%), Gaps = 17/246 (6%) Query: 10 NWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVF--LPLVKSTL-RSDFFVAAQN 66 NWKCNG+ + + ++++ N + V+ VV+P + + K L F +AAQN Sbjct: 11 NWKCNGSQQSLSELIDLFNSTSINHD--VQCVVAPSWYMGAQAMTKERLSHPKFVIAAQN 68 Query: 67 CWVKKGGAFTGEVSA-EMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVI 125 G A L + I W++L HSERRA E++E V DKVA A+A G VI Sbjct: 69 A---------GNADALASLKDFGISWIVLDHSERRAYYGETNEIVADKVAAAVASGFMVI 119 Query: 126 ACVGETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTGKVASPAQAQ 183 AC+GETL+ER +G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+P QAQ Sbjct: 120 ACIGETLQERSSGRTAVVVLTQITAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQQAQ 179 Query: 184 EVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFID 243 E H +R W++ V ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLKPEF+D Sbjct: 180 EAHALIRSWVSSKVGADVAGELRILYGGSVNGRNARTLYQQRDVNGFLVGGASLKPEFVD 239 Query: 244 IIKAAE 249 IIKA E Sbjct: 240 IIKATE 245 >1B9B-A nrPDB Length = 255 Score = 200 bits (509), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 115/250 (46%), Positives = 148/250 (59%), Gaps = 6/250 (2%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTL-NEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-S 58 + RK + GNWK + T E KK V+ L NE + E+VV PP+ L V L Sbjct: 1 ITRKLILAGNWKMHKTISEAKKFVSLLVNELHDVKE--FEIVVCPPFTALSEVGEILSGR 58 Query: 59 DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYAL 118 + + AQN + + GAFTGE+S ML + + +VI+GHSERR I E EF+ KV L Sbjct: 59 NIKLGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVL 118 Query: 119 AQGLKVIACVGETLEEREAGSTMDVVAAQTKA--IADRVTNWSNVVIAYEPVWAIGTGKV 176 +G+ I CVGETLEERE G T VV Q + VVIAYEPVWAIGTG+V Sbjct: 119 EKGMTPILCVGETLEEREKGLTFCVVEKQVREGFYGLDKEEAKRVVIAYEPVWAIGTGRV 178 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 A+P QAQEVH +RK L++ + A + RI+YGGS+ N L Q D+DG LVGGAS Sbjct: 179 ATPQQAQEVHAFIRKLLSEMYDEETAGSIRILYGGSIKPDNFLGLIVQKDIDGGLVGGAS 238 Query: 237 LKPEFIDIIK 246 LK FI++ + Sbjct: 239 LKESFIELAR 248 >4Y96-A nrPDB Length = 255 Score = 194 bits (493), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 119/250 (47%), Positives = 149/250 (59%), Gaps = 6/250 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDFF 61 RK FV GNWK N T E K + + A+ + D V V V PPY +L V L+ S Sbjct: 7 RKKFVAGNWKMNTTLAEAKALGAAV--AKGVTDDRVTVAVFPPYPWLTAVGEVLKGSPVA 64 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQ+ +K GAFTGEVS ML+ + ++GHSERR I+ ES F+ KV AL +G Sbjct: 65 LGAQDVSSEKKGAFTGEVSPAMLLETGCKYALIGHSERRHIIGESETFINHKVHTALEEG 124 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASP 179 L V+ C+GETL ERE G V Q A +T+ + +VIAYEPVWAIGTGKVA+P Sbjct: 125 LSVVLCMGETLAERERGLQERVFQRQVYAACAGLTDEQFGRIVIAYEPVWAIGTGKVATP 184 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 QAQE H +R L +A +T I+YGGSV N L Q DVDG LVGGASLK Sbjct: 185 EQAQEAHAFVRSKLRLLYGDKIADSTPIVYGGSVTPDNTVGLMSQPDVDGALVGGASLKA 244 Query: 240 E-FIDIIKAA 248 + F+ I+KAA Sbjct: 245 DSFLAIVKAA 254 >1BTM-A nrPDB Length = 252 Score = 180 bits (456), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 108/249 (43%), Positives = 145/249 (58%), Gaps = 5/249 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLP-LVKSTLRSDFF 61 RK + GNWK + T E + V + + VP D V VV P++FL LV++ +D Sbjct: 1 RKPIIAGNWKMHKTLAEAVQFVEDV-KGHVPPADEVISVVCAPFLFLDRLVQAADGTDLK 59 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQ GA+TGEVS ML +L + +VILGHSERR + E+ E V KV A +G Sbjct: 60 IGAQTMHFADQGAYTGEVSPVMLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRG 119 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQT-KAIADRVTNW-SNVVIAYEPVWAIGTGKVASP 179 L I C GE+LEEREAG T VVA+Q KA+A VIAYEP+WAIGTGK ++P Sbjct: 120 LIPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQAVIAYEPIWAIGTGKSSTP 179 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 A V +R +++ + A RI YGGSV N ++ Q +DG LVGGASL+P Sbjct: 180 EDANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGPLVGGASLEP 239 Query: 240 -EFIDIIKA 247 F+ +++A Sbjct: 240 ASFLQLVEA 248 >3UWW-A nrPDB Length = 261 Score = 179 bits (454), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 105/254 (41%), Positives = 146/254 (57%), Gaps = 9/254 (3%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR----S 58 R + GNWK N T +E K VN L +P VE V+ P + L + + ++ Sbjct: 10 RTPIIAGNWKMNKTVQEAKDFVNAL--PTLPDSKEVESVICAPAIQLDALTTAVKEGKAQ 67 Query: 59 DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYAL 118 + AQN + + GAFTGE S L +L + +V++GHSERR + +E+ E + K Sbjct: 68 GLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIF 127 Query: 119 AQGLKVIACVGETLEEREAGSTMDVVAAQTK-AIADRVTN-WSNVVIAYEPVWAIGTGKV 176 G+ I CVGET EERE+G DVV Q K A+A + +VVIAYEP+WAIGTGK Sbjct: 128 KHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKS 187 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 ++ A E+ +R+ +A S +V+ TRI YGGSV N KE Q D+DG LVGGAS Sbjct: 188 STSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGAS 247 Query: 237 LKPE-FIDIIKAAE 249 LK E F+ +++ A+ Sbjct: 248 LKVEDFVQLLEGAK 261 >4Y8F-A nrPDB Length = 251 Score = 177 bits (450), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 105/238 (44%), Positives = 138/238 (57%), Gaps = 5/238 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDFF 61 R + GNWK + T +E K+V L ++ EVVV P +V L VK + ++ Sbjct: 5 RTPIIAGNWKMHYTIDEAVKLVEELKPLVKDAK--CEVVVCPTFVCLDAVKKAVEGTNIK 62 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 V AQN ++ GAFTGE++ ML ++I +VI+GHSERR NE+ E KV A A Sbjct: 63 VGAQNMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHN 122 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASP 179 L I C GETLE+RE G+T DV+ AQ A + +T VVIAYEP+WAIGTGK A+ Sbjct: 123 LTPILCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATS 182 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 QA E +R +A+ +VA RI YGGSV E ++D+DG LVGGASL Sbjct: 183 DQANETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASL 240 >5IBX-C nrPDB Length = 255 Score = 175 bits (443), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 104/253 (41%), Positives = 144/253 (56%), Gaps = 8/253 (3%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SD 59 M+RK F+ GNWK N EE K V + +++PS D+VE ++ P + L V + + S+ Sbjct: 4 MSRKPFIAGNWKMNKNPEEAKAFVEAV-ASKLPSSDLVEAGIAAPALDLTTVLAVAKGSN 62 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 VAAQNC+ + GAFTGE S ++L + +V++GHSERR +E+ E + K A Sbjct: 63 LKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFA 122 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVA 177 G+ I C GE+LE EAG + V AQ A +T + VIAYEP+WAIGTGK A Sbjct: 123 NGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSA 182 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 S AQ++ +R +A + +VA R+ YGGSV N DVDG LVGGASL Sbjct: 183 SQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASL 242 Query: 238 KPE----FIDIIK 246 + E +D +K Sbjct: 243 EAESFLALLDFVK 255 >4X22-A nrPDB Length = 250 Score = 174 bits (442), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 102/243 (41%), Positives = 152/243 (62%), Gaps = 9/243 (3%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPS--QDVVEVVVSPPYVFLPLVKSTLR-SD 59 RK + GNWK N + +E + +++ E ++PS +D V +V P + L V L S Sbjct: 2 RKTIIAGNWKMNLSLKEAVFLAHSIRE-KIPSISKDKVSMVF-PSTLHLENVSKILEGSS 59 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 V AQNC+ AFTGE S + L + + V++GHSERR L ES+ F DK+ + L Sbjct: 60 VIVGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLLK 119 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVA 177 V+ CVGETL ERE+G T++V+++Q + + + +SN+++AYEPVWAIGTGKVA Sbjct: 120 NEFTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKVA 179 Query: 178 SPAQAQEVHDELRKWLAKNV--SADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA 235 +P+QAQEVH +RK ++ ++ ++ + I+YGGSV N ++L + D+DG LVGGA Sbjct: 180 TPSQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGGA 239 Query: 236 SLK 238 S K Sbjct: 240 SQK 242 >5UJW-A nrPDB Length = 253 Score = 171 bits (434), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 99/246 (40%), Positives = 144/246 (58%), Gaps = 5/246 (2%) Query: 6 FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQ 65 + GNWK NG + +K++ + +++ Q + V + V P V++ V S L V Q Sbjct: 4 LIMGNWKMNGNSTSIKELCSGISQVQYDTSRVA-IAVFPSSVYVKEVISQLPEKVGVGLQ 62 Query: 66 NCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVI 125 N GA+TGE+SA ML ++ ++++GHSERR++ ES E V K+ + + + Sbjct: 63 NITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPV 122 Query: 126 ACVGETLEEREAGSTMDVVAAQTKAIADR--VTNWSNVVIAYEPVWAIGTGKVASPAQAQ 183 C+GE+L++R++G V+A Q I + V + VVIAYEPVWAIGTG VAS Q Q Sbjct: 123 VCIGESLDDRQSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQIQ 182 Query: 184 EVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEFI 242 E H +R LAK V +A +I+YGGS+ N K++ DVDG L+GGASLK EF Sbjct: 183 ETHQFIRSLLAK-VDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEFN 241 Query: 243 DIIKAA 248 +II A Sbjct: 242 EIINQA 247 >1AW2-A nrPDB Length = 256 Score = 170 bits (430), Expect = 6e-43, Method: Compositional matrix adjust. Identities = 102/240 (42%), Positives = 135/240 (56%), Gaps = 7/240 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR---SD 59 R V GNWK NG+ E V ++N LN A++ V+V V+PP +F+ L + TL S Sbjct: 2 RHPVVMGNWKLNGSKEMVVDLLNGLN-AELEGVTGVDVAVAPPALFVDLAERTLTEAGSA 60 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 + AQN + GAFTG++S ML +I+GHSERR ES EFV K A+ Sbjct: 61 IILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHAESDEFVAKKFAFLKE 120 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADR--VTNWSNVVIAYEPVWAIGTGKVA 177 GL + C+GE+ + EAG TM V A Q A+ + V +IAYEP+WAIGTGK A Sbjct: 121 NGLTPVLCIGESDAQNEAGETMAVCARQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAA 180 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 + AQ +H ++R +A+ A VA I YGGSV N Q D+DG LVGGA+L Sbjct: 181 TAEDAQRIHAQIRAHIAEKSEA-VAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAAL 239 >4G1K-A nrPDB Length = 272 Score = 166 bits (419), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 104/245 (42%), Positives = 144/245 (58%), Gaps = 8/245 (3%) Query: 9 GNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV-AAQNC 67 GNWK +G + ++ + + D V + V P+ +L ++ L+ +Q+ Sbjct: 32 GNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQDV 91 Query: 68 WVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIAC 127 + GA+TGEV+A M+ + I+GHSERRA ES+E V K ALA GL I C Sbjct: 92 SAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPIVC 151 Query: 128 VGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASPAQAQEV 185 VGETL EREAG+T VV AQ A+ ++ + +V+AYEPVWAIGTGK A+ QAQ+V Sbjct: 152 VGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGKSATAEQAQQV 211 Query: 186 HDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP-EFIDI 244 H LR LA + V+ ++YGGSV N EL GQ D+DG L+GGASLK +F+ I Sbjct: 212 HAFLRGRLAAKGAGHVS----LLYGGSVKADNAAELFGQPDIDGGLIGGASLKSGDFLAI 267 Query: 245 IKAAE 249 +AA+ Sbjct: 268 CRAAK 272 >1YYA-A nrPDB Length = 250 Score = 166 bits (419), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 101/250 (40%), Positives = 135/250 (54%), Gaps = 6/250 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFF 61 R+ V GNWK + T E + L P Q E V P + LP+ K L + Sbjct: 2 RRVLVAGNWKMHKTPSEARVWFAELKRLLPPLQS--EAAVLPAFPILPVAKEVLAETQVG 59 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 AQ+ K GA+TGEVSA ML +L + I+GHSERR E+ V +K L +G Sbjct: 60 YGAQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEG 119 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTGKVASP 179 + I CVGE LE RE G + Q + + V +VIAYEPVWAIGTGK A+P Sbjct: 120 ITPILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATP 179 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 A+ +H +RK L++ A+ RI+YGGSVN N +L +VDG LVGGASL+ Sbjct: 180 EDAEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLEL 239 Query: 240 E-FIDIIKAA 248 E F+ +++ A Sbjct: 240 ESFLALLRIA 249 >4Y9A-A nrPDB Length = 261 Score = 163 bits (413), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 107/251 (42%), Positives = 136/251 (54%), Gaps = 7/251 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQ-DVVEVVVSPPYVFLPLVKSTLRSDFF 61 R + GNWK N E V L A D VEV V P+ L V++ + D Sbjct: 7 RTPLMAGNWKMNLNHLEAIAHVQKLAFALADKDYDAVEVAVLAPFTDLRSVQTLVDGDKL 66 Query: 62 ---VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYAL 118 AQ+ GGA+TGE+S ML L +V +GHSERR E+ E V KV A Sbjct: 67 KIKYGAQDISAHDGGAYTGEISGPMLAKLKCTYVAVGHSERRQYHAETDEIVNAKVKAAY 126 Query: 119 AQGLKVIACVGETLEEREAGSTMDVVAAQTKA-IADRVTNWS-NVVIAYEPVWAIGTGKV 176 GL I CVGE L+ REAG+ ++ AQ + + D + +VVIAYEPVWAIGTGKV Sbjct: 127 KHGLTPILCVGEELDVREAGNHVEHTLAQVEGGLKDLAAEQAESVVIAYEPVWAIGTGKV 186 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 AQEV +R LA+ S ++A RI YGGSV GN E+ + D+DG LVGGAS Sbjct: 187 CGADDAQEVCAAIRGKLAELYSQELADKVRIQYGGSVKSGNVAEIMAKPDIDGALVGGAS 246 Query: 237 LKP-EFIDIIK 246 L EF+ I++ Sbjct: 247 LDSDEFVKIVR 257 >3TA6-A nrPDB Length = 267 Score = 162 bits (410), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 110/259 (42%), Positives = 144/259 (55%), Gaps = 18/259 (6%) Query: 1 MARKFFVGGNWKCNGTAEE----VKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL 56 M+RK + GNWK N E V+KI +L + D V+V V PP+ L V++ + Sbjct: 1 MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYY---DRVDVAVIPPFTDLRSVQTLV 57 Query: 57 RSD---FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDK 113 D AQ+ GA+TG+VS L L +V++GHSERR NE V K Sbjct: 58 DGDKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAK 117 Query: 114 VAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKA-----IADRVTNWSNVVIAYEPV 168 A AL GL I C+GE L+ REAG+ + Q + +A+++ +VVIAYEPV Sbjct: 118 AATALKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQI---GSVVIAYEPV 174 Query: 169 WAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVD 228 WAIGTG+VAS A AQEV +RK LA S +A T R++YGGSVN N ++ Q DVD Sbjct: 175 WAIGTGRVASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVD 234 Query: 229 GFLVGGASLKPEFIDIIKA 247 G LVGGASL E + A Sbjct: 235 GGLVGGASLDGEHFATLAA 253 >3KXQ-A nrPDB Length = 275 Score = 152 bits (385), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 92/248 (37%), Positives = 125/248 (50%), Gaps = 4/248 (1%) Query: 6 FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD-FFVAA 64 F+ GNWK NGT E + ++ + E ++ P L L + + Sbjct: 29 FIAGNWKMNGTGESLGELRAIAAGISSDLGRLFEALICVPATLLSRAFDILGGENILLGG 88 Query: 65 QNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKV 124 QNC G +TG++SA ML VI+GHSERR + ES V KV A GL Sbjct: 89 QNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWRAGLVA 148 Query: 125 IACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQE 184 + CVGETLEER++ +DV+ Q + N++IAYEPVWA+GTG A+ A E Sbjct: 149 LICVGETLEERKSNKVLDVLTRQLEGSLPDGATAENIIIAYEPVWAVGTGNTATSADVAE 208 Query: 185 VHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFIDI 244 VH + + D A R++YGGSV N EL A V+G L+GGASLK ID Sbjct: 209 VHAFIHHKMHSRF-GDEGAKIRLLYGGSVKPSNAFELLSTAHVNGALIGGASLKA--IDF 265 Query: 245 IKAAEVKK 252 + +V + Sbjct: 266 LTICDVYR 273 >4NVT-A nrPDB Length = 262 Score = 149 bits (376), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 102/248 (41%), Positives = 133/248 (53%), Gaps = 17/248 (6%) Query: 6 FVGGNWKCNGTAE---EVKKIVNTLNEAQVPSQDV---VEVVVSPPYVFLPLVKSTLRSD 59 V GNWK NG E E++ I L S D+ ++ V+ P L TL + Sbjct: 16 LVAGNWKMNGKGESLTELRAIAAGL------SSDLGRKLDAVICVPATLLSRAAETLEGE 69 Query: 60 FF-VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYAL 118 + Q+ K GA TG++S EML VILGHSERR +ES++ + K A Sbjct: 70 TVGLGGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAW 129 Query: 119 AQGLKVIACVGETLEEREAGSTMDVVAAQ-TKAIADRVTNWSNVVIAYEPVWAIGTGKVA 177 A GL I CVGET ER+A +DV+ Q + ++ D VT N +IAYEPVWAIGTG Sbjct: 130 AAGLVAIVCVGETASERKAERALDVIGDQLSGSLPDGVTA-ENTIIAYEPVWAIGTGLTP 188 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 + + H +R+ L + A A R++YGGSV N EL G ADVDG LVGGASL Sbjct: 189 TVQDVRAAHAFMREQLIERFGAK-GAHLRLLYGGSVKPSNAAELLGVADVDGALVGGASL 247 Query: 238 K-PEFIDI 244 K +F+ I Sbjct: 248 KAADFLAI 255 >6BVE-A nrPDB Length = 245 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 91/239 (38%), Positives = 127/239 (53%), Gaps = 9/239 (3%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFF 61 RK + GNWK + T E + + + + EVV+ P+ L + L Sbjct: 5 RKIIIAGNWKMHKTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVR 64 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQN + GA+TGE+SA ML + I +V++GHSERR E+ E +V A G Sbjct: 65 LGAQNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLAAQKAG 124 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L I CVGE+ +R+AG T V+ Q K V + SN+VIAYEP+WAIGTG + + Sbjct: 125 LIPILCVGESKAQRDAGETEQVIVDQVKKGLVNV-DQSNLVIAYEPIWAIGTGDTCAATE 183 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 A V +R+ L + I YGGSVN N E+ Q ++DG LVGGASL+P+ Sbjct: 184 ANRVIGLIREQLTN-------SQVTIQYGGSVNANNVDEIMAQPEIDGALVGGASLEPQ 235 >4Y90-A nrPDB Length = 247 Score = 138 bits (347), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 92/239 (38%), Positives = 131/239 (54%), Gaps = 5/239 (2%) Query: 10 NWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWV 69 NWK N T E + L P++ V ++ V P + L + + L + Q+ Sbjct: 11 NWKMNKTPTEARSWAEELTTKYAPAEGV-DLAVLAPALDLSALAANLPAGIAFGGQDVSA 69 Query: 70 KKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVG 129 + GA+TGE+SA ML + V++GHSERR +ES V K A A GL I CVG Sbjct: 70 HESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDATVAAKARQAQANGLLPIVCVG 129 Query: 130 ETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDEL 189 E L+ RE G + AQ + + V ++VV+AYEPVWAIGTGK A+ A+E+ + Sbjct: 130 ENLDVRERGEHVPQTLAQLRGSLEGVG--ADVVVAYEPVWAIGTGKTATADDAEELAAAI 187 Query: 190 RKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEFIDIIKA 247 R L + A A R++YGGSV N E+ G+ +V+G LVGGASLK P+ + ++ A Sbjct: 188 RGALREQYGAR-AEGIRVLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGMLDA 245 >2JGQ-A nrPDB Length = 233 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 78/210 (37%), Positives = 115/210 (54%), Gaps = 16/210 (7%) Query: 29 EAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLD 88 E + Q V V P + L L S L F + QN + + GAFTGE++++ L L Sbjct: 25 EKTLKPQHFDRVFVFPDFFGL-LPNSFLH--FTLGVQNAYPRDCGAFTGEITSKHLEELK 81 Query: 89 IPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAG--STMDVVAA 146 I +++GHSERR +L ES F+ +K + ++ K++ C+GE L RE G + + ++ Sbjct: 82 IHTLLIGHSERRTLLKESPSFLKEKFDFFKSKNFKIVYCIGEELTTREKGFKAVKEFLSE 141 Query: 147 QTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTR 206 Q + I N+ N+V+AYEP+WAIGT K AS H L++ L + T Sbjct: 142 QLENID---LNYPNLVVAYEPIWAIGTKKSASLEDIYLTHGFLKQILNQK--------TP 190 Query: 207 IIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 ++YGGSVN N KE+ G VDG L+G AS Sbjct: 191 LLYGGSVNTQNAKEILGIDSVDGLLIGSAS 220 >3S6D-A nrPDB Length = 310 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 57/179 (31%), Positives = 87/179 (48%), Gaps = 6/179 (3%) Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 + AQ+C+ G +TGE+S L ++++ V LGH+ERRAI E+ + V K A A Sbjct: 112 LLLGAQDCFWDSLGPYTGEISPVCLRDMNVSIVELGHAERRAIFGETDQQVARKAAAAAD 171 Query: 120 QGLKVIACVGE-----TLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTG 174 QGL + C+GE + G + AQ + + + + + V+ AYEPVWAIG Sbjct: 172 QGLIPLVCIGEVSTLGPIVSEAIGRAVGECEAQIRPVLEALPRDAPVIFAYEPVWAIGKP 231 Query: 175 KVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVG 233 + A V +R + + + RI+YGGS G G +VDG +G Sbjct: 232 QPARVDHVGAVVSGIRSVIER-IDRHRKGEVRILYGGSAGPGLWGPGGLGKEVDGMFLG 289 >5CSS-A nrPDB Length = 226 Score = 47.0 bits (110), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 46/171 (26%), Positives = 69/171 (40%), Gaps = 24/171 (14%) Query: 33 PSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWV 92 P Q E++ SP L L K+ F AQ+ + GA+TG V +M+++L I Sbjct: 30 PVQGKFELIFSPS--LLDLEKAAKCGKFRFFAQHVDAEPYGAYTGHVPMDMMIDLGITGS 87 Query: 93 ILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIA 152 IL HSERR + + + + A ++ CV E EE A Sbjct: 88 ILNHSERRL----PRDTIINTLKKASKLDFTIVLCV-ENAEE-----------------A 125 Query: 153 DRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAA 203 + IAYEP IG S A+ + + D ++ + S V A Sbjct: 126 KYFREYEPDFIAYEPRDLIGGDVSVSTAKPEIIEDIVKIYEGTGTSVLVGA 176 >1W0M-A nrPDB Length = 226 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 34/90 (37%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 38 VEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHS 97 V +VV+P ++ L LV ++ D V AQ V+ GGA T VS E + VIL HS Sbjct: 37 VNIVVAPNHLELGLVSQSV--DIPVYAQGADVEAGGAHTAHVSLENIKEAGGSGVILNHS 94 Query: 98 ERRAILNESSEFVGDKVAYALAQGLKVIAC 127 E LN+ + VA A + GL V+ C Sbjct: 95 EAPLKLNDLARL----VAKAKSLGLDVVVC 120 >1HG3-A nrPDB Length = 225 Score = 35.0 bits (79), Expect = 0.028, Method: Compositional matrix adjust. Identities = 43/179 (24%), Positives = 73/179 (40%), Gaps = 30/179 (16%) Query: 38 VEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHS 97 V +VV+P V L ++ ++ F AQ+ K G+ TG V E + +L HS Sbjct: 40 VTIVVAPQLVDLRMIAESVEIPVF--AQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHS 97 Query: 98 ERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN 157 E R IL A + + E M +V + A++ V Sbjct: 98 ENRMIL----------------------ADLEAAIRRAEEVGLMTMVCSNNPAVSAAVAA 135 Query: 158 WSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGG 216 + +A EP IGTG S A+ + + + + L K V+ +V +++ G ++ G Sbjct: 136 LNPDYVAVEPPELIGTGIPVSKAKPEVITNTVE--LVKKVNPEV----KVLCGAGISTG 188 >2H6R-A nrPDB Length = 219 Score = 34.3 bits (77), Expect = 0.048, Method: Compositional matrix adjust. Identities = 47/186 (25%), Positives = 79/186 (42%), Gaps = 30/186 (16%) Query: 31 QVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIP 90 +V + + + V+P +V L ++ + + V AQ+ G+ TG + AE + + Sbjct: 27 KVSEESGITIGVAPQFVDLRMIVENV--NIPVYAQHIDNINPGSHTGHILAEAIKDCGCK 84 Query: 91 WVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKA 150 ++ HSE+R +L + E V +K GL+ I C +T VAA Sbjct: 85 GTLINHSEKRMLLAD-IEAVINKCKNL---GLETIVCTNNI-------NTSKAVAA---- 129 Query: 151 IADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYG 210 S IA EP IGTG S A + V +R K ++ DV +++ G Sbjct: 130 -------LSPDCIAVEPPELIGTGIPVSKANPEVVEGTVRA--VKEINKDV----KVLCG 176 Query: 211 GSVNGG 216 ++ G Sbjct: 177 AGISKG 182 >5X3F-A nrPDB Length = 501 Score = 30.0 bits (66), Expect = 0.93, Method: Compositional matrix adjust. Identities = 28/110 (25%), Positives = 47/110 (42%), Gaps = 4/110 (3%) Query: 94 LGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGET-LEEREAGSTMDVVAAQTKAIA 152 L H E +A+ E E+ + V + K + G+ E +AGS +V Q + Sbjct: 24 LDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFI 83 Query: 153 DRVTNWSNVVIAYEP---VWAIGTGKVASPAQAQEVHDELRKWLAKNVSA 199 D + + + + V A+ P +QE+ D LR LAK ++A Sbjct: 84 DCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAA 133 >3PIH-A nrPDB Length = 916 Score = 29.6 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 26/57 (45%) Query: 171 IGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADV 227 IG ++PA +V DE+R A +A + + ++ GG C+ GQ V Sbjct: 669 IGRTPRSNPATYTKVFDEIRSLFAMTPAAKARGYNKSRFSFNLKGGRCEACQGQGYV 725 >5CED-A nrPDB Length = 446 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 22/41 (53%) Query: 132 LEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIG 172 ++ E +TM +++A K I R+ N SN IA W +G Sbjct: 224 FQKNEKSTTMVLMSAPLKTILKRMNNQSNNYIADNLYWNLG 264 >4IVN-A nrPDB Length = 278 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 50 PLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEF 109 PL S+L ++ VAA+ GGAF +V A +LV++ + ++ + E + + E++E Sbjct: 214 PL--SSLSTEMLVAARPEGPLTGGAFASKVGALLLVDVLVNSLLESYPEYKDSVQETAEV 271 Query: 110 V 110 V Sbjct: 272 V 272 >4NEF-A nrPDB Length = 242 Score = 28.1 bits (61), Expect = 4.2, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Query: 54 STLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDK 113 S LR+ F+VAAQ G A E++ P I G A+ N ++ G Sbjct: 82 SVLRAAFYVAAQLLGAVAGAALLHEIT---------PADIRGDLAVNALSNSTTA--GQA 130 Query: 114 VAYALAQGLKVIACVGETLEERE 136 V L L+++ C+ + +ER Sbjct: 131 VTVELFLTLQLVLCIFASTDERR 153 >4OJ2-X nrPDB Length = 274 Score = 27.7 bits (60), Expect = 5.5, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 11/83 (13%) Query: 54 STLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDK 113 S LR+ F+VAAQ G A E++ P I G A+ N ++ G Sbjct: 85 SVLRAAFYVAAQLLGAVAGAALLHEIT---------PADIRGDLAVNALSNSTTA--GQA 133 Query: 114 VAYALAQGLKVIACVGETLEERE 136 V L L+++ C+ + +ER Sbjct: 134 VTVELFLTLQLVLCIFASTDERR 156 >1Z1W-A nrPDB Length = 780 Score = 27.3 bits (59), Expect = 6.7, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 33/62 (53%), Gaps = 6/62 (9%) Query: 75 FTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDK-VAYALAQGLKVIACVGETLE 133 FTG +A V + IP + L H + I+ +G K ++ LA+G++++A V L Sbjct: 717 FTGNRTASRTVEMMIPVIGLDHPDAEDIVRN----IGSKNISMGLAKGIEMLA-VNRKLV 771 Query: 134 ER 135 ER Sbjct: 772 ER 773 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4OBT-A nrPDB 409 e-115 6CG9-A nrPDB 406 e-114 6NEE-A nrPDB 405 e-113 3TH6-A nrPDB 394 e-110 2I9E-A nrPDB 393 e-110 5ZGA-A nrPDB 391 e-109 4POC-A nrPDB 387 e-108 1SW7-A nrPDB 380 e-106 1MO0-A nrPDB 378 e-105 5EYW-A nrPDB 375 e-105 4OHQ-A nrPDB 370 e-103 3KRS-A nrPDB 363 e-101 2VXN-A nrPDB 359 e-100 5CG7-A nrPDB 358 1e-99 1LZO-A nrPDB 358 2e-99 1I45-A nrPDB 356 5e-99 4MKN-A nrPDB 355 9e-99 1CI1-A nrPDB 353 3e-98 3Q37-A nrPDB 346 4e-96 1B9B-A nrPDB 340 3e-94 1KV5-A nrPDB 339 8e-94 3PF3-A nrPDB 338 1e-93 1TMH-A nrPDB 333 4e-92 5VWN-A nrPDB 333 5e-92 5UPR-A nrPDB 331 1e-91 1BTM-A nrPDB 330 4e-91 2V5B-A nrPDB 329 5e-91 4Y8F-A nrPDB 329 9e-91 4Y96-A nrPDB 323 3e-89 3UWW-A nrPDB 321 1e-88 1M6J-A nrPDB 320 4e-88 1TRI-A nrPDB 319 8e-88 5IBX-C nrPDB 318 2e-87 4Y9A-A nrPDB 317 3e-87 1YYA-A nrPDB 315 9e-87 2Y70-A nrPDB 314 3e-86 5UJW-A nrPDB 308 1e-84 3KXQ-A nrPDB 306 5e-84 6BVE-A nrPDB 301 3e-82 4X22-A nrPDB 298 1e-81 1AW2-A nrPDB 298 2e-81 3TA6-A nrPDB 297 3e-81 4NVT-A nrPDB 297 3e-81 4G1K-A nrPDB 289 1e-78 4Y90-A nrPDB 278 2e-75 2JGQ-A nrPDB 217 5e-57 3S6D-A nrPDB 187 4e-48 5CSS-A nrPDB 138 2e-33 1W0M-A nrPDB 91 4e-19 Sequences not found previously or not previously below threshold: 2H6R-A nrPDB 82 2e-16 1HG3-A nrPDB 77 8e-15 1E6V-A nrPDB 33 0.18 6OKK-M nrPDB 29 1.6 3AGK-A nrPDB 29 1.9 2RUS-A nrPDB 29 2.3 3KW2-A nrPDB 29 2.6 3K9D-A nrPDB 29 2.6 5LZY-jj nrPDB 28 3.1 5FGE-J nrPDB 28 3.5 3WXR-K nrPDB 28 3.5 4AF1-A nrPDB 28 4.6 3MBJ-A nrPDB 28 5.1 3H9B-A nrPDB 28 5.1 6GKI-A nrPDB 28 5.4 6HIV-CJ nrPDB 27 7.5 4NNP-A nrPDB 27 7.5 2VOU-A nrPDB 27 9.0 >4OBT-A nrPDB Length = 257 Score = 409 bits (1051), Expect = e-115, Method: Composition-based stats. Identities = 254/254 (100%), Positives = 254/254 (100%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF Sbjct: 4 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 63 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ Sbjct: 64 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 123 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA Sbjct: 124 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 183 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE Sbjct: 184 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 243 Query: 241 FIDIIKAAEVKKSA 254 FIDIIKAAEVKKSA Sbjct: 244 FIDIIKAAEVKKSA 257 >6CG9-A nrPDB Length = 256 Score = 406 bits (1044), Expect = e-114, Method: Composition-based stats. Identities = 205/253 (81%), Positives = 224/253 (88%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 M RKFFVGGNWKCNGT ++V+KIV TLNE QVP DVVEVVVSPPYVFLP+VKS LR +F Sbjct: 4 MGRKFFVGGNWKCNGTTDQVEKIVKTLNEGQVPPSDVVEVVVSPPYVFLPVVKSQLRQEF 63 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 VAAQNCWVKKGGAFTGEVSAEMLVNL +PWVILGHSERRA+L ES+EFVGDKVAYAL+Q Sbjct: 64 HVAAQNCWVKKGGAFTGEVSAEMLVNLGVPWVILGHSERRALLGESNEFVGDKVAYALSQ 123 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GLKVIACVGETLE+REAGSTMDVVAAQTKAIA+++ +WSNVV+AYEPVWAIGTGKVA+PA Sbjct: 124 GLKVIACVGETLEQREAGSTMDVVAAQTKAIAEKIKDWSNVVVAYEPVWAIGTGKVATPA 183 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVH LR WL N S +VA +TRIIYGGSV NCKEL Q DVDGFLVGGASLKPE Sbjct: 184 QAQEVHASLRDWLKTNASPEVAESTRIIYGGSVTAANCKELAAQPDVDGFLVGGASLKPE 243 Query: 241 FIDIIKAAEVKKS 253 FIDII AA VK + Sbjct: 244 FIDIINAATVKSA 256 >6NEE-A nrPDB Length = 252 Score = 405 bits (1040), Expect = e-113, Method: Composition-based stats. Identities = 171/252 (67%), Positives = 198/252 (78%), Gaps = 6/252 (2%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL--RSD 59 +RKFFVGGNWK NGT E +K +V TLN AQ+ EVVV+PP ++LP +S L + Sbjct: 3 SRKFFVGGNWKMNGTLESIKALVETLNSAQLDPN--TEVVVAPPAIYLPFARSKLKKPKE 60 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 VAAQNC+ K GAFTGE+SAEML +L +PWVILGHSERR I ES E + +KV YAL Sbjct: 61 IQVAAQNCYTKPNGAFTGEISAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALD 120 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQT-KAIADRVTNWSNVVIAYEPVWAIGTGKVAS 178 QGLKVIAC+GETLEEREAG TM+VVA Q KAIAD++ +WSNVVIAYEPVWAIGTGKVA+ Sbjct: 121 QGLKVIACIGETLEEREAGKTMEVVARQILKAIADKIKDWSNVVIAYEPVWAIGTGKVAT 180 Query: 179 PAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK 238 P QAQEVH LRKWL +NVS +VA +TRIIYGGSVN NCKEL Q D+DGFLVGGASLK Sbjct: 181 PEQAQEVHAALRKWLKENVSPEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLK 240 Query: 239 -PEFIDIIKAAE 249 PEF+DII A + Sbjct: 241 APEFVDIINARQ 252 >3TH6-A nrPDB Length = 249 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 140/248 (56%), Positives = 174/248 (70%), Gaps = 2/248 (0%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 AR+F VGGNWK +G+ ++ I NTL A + VEV+V+ P +L +S L Sbjct: 3 ARRFCVGGNWKMHGSKNSIRDICNTLKGASLDPN--VEVIVACPAPYLDYCRSLLPPSVA 60 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 +AAQNC+ + GAFTGE+S M+ + WVILGHSERR + E +G+K+ +AL G Sbjct: 61 LAAQNCYKVEQGAFTGEISPGMIKDCGGQWVILGHSERRHVFKEDDVLIGEKIKHALESG 120 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L VIAC+GE LE+REAG T +V Q K IA V +WS VVIAYEPVWAIGTGK A+P Q Sbjct: 121 LNVIACIGELLEDREAGRTEEVCFRQIKHIASNVKDWSKVVIAYEPVWAIGTGKTATPDQ 180 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEF 241 AQEVH ++R WL+ NVSADVA+ RI YGGSVN GNCKELG + D+DGFLVGGASLKPEF Sbjct: 181 AQEVHSKVRNWLSTNVSADVASKVRIQYGGSVNAGNCKELGRKPDIDGFLVGGASLKPEF 240 Query: 242 IDIIKAAE 249 + II A + Sbjct: 241 VQIINAMQ 248 >2I9E-A nrPDB Length = 259 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 146/250 (58%), Positives = 180/250 (72%), Gaps = 2/250 (0%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 MARKF VGGNWK NG +++ +I+ L P EVVV P ++L LV++ + + Sbjct: 1 MARKFVVGGNWKMNGDKKQINEIIGFLKSG--PLNQDTEVVVGVPAIYLELVRTCVPASI 58 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 VAAQNC+ GAFTGE+S M+ ++ WVILGHSERR I ES E + +KV +AL Sbjct: 59 GVAAQNCYKVPKGAFTGEISPAMIKDVGADWVILGHSERRQIFGESDELIAEKVCHALES 118 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GLKVIAC+GETLEEREAG T +VV QTKAIA +V +WSNVVIAYEPVWAIGTGK A+P Sbjct: 119 GLKVIACIGETLEEREAGKTEEVVFRQTKAIAAKVNDWSNVVIAYEPVWAIGTGKTATPQ 178 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQ+VH LR+W+ +N+ A V + RI YGGSV NCKEL Q D+DGFLVGGASLKPE Sbjct: 179 QAQDVHKALRQWICENIDAKVGNSIRIQYGGSVTAANCKELASQPDIDGFLVGGASLKPE 238 Query: 241 FIDIIKAAEV 250 F+DII A ++ Sbjct: 239 FVDIINARQL 248 >5ZGA-A nrPDB Length = 269 Score = 391 bits (1004), Expect = e-109, Method: Composition-based stats. Identities = 137/245 (55%), Positives = 175/245 (71%), Gaps = 2/245 (0%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 RKFFVGGNWK NG+ +E K++ L A++ EV+V+PP ++LP V+ L F V Sbjct: 25 RKFFVGGNWKMNGSKKENDKLIEMLTHAKIDPN--TEVLVAPPALYLPSVREKLDKRFHV 82 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQNC+ GAFTGEVS ML ++ WVILGHSERR IL E+ + VG+K A+A++ G+ Sbjct: 83 AAQNCYKVPSGAFTGEVSPAMLKDVGCDWVILGHSERRHILLETDQLVGEKTAHAISAGV 142 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 VIAC+GE LEEREAG T +V Q +AI ++ W+++VIAYEPVWAIGTGK A+ QA Sbjct: 143 NVIACIGEKLEEREAGKTEEVCFRQMEAIRKNLSMWNHIVIAYEPVWAIGTGKTATEQQA 202 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH +R+W+ + VS VA + RIIYGGSV NC+ L Q DVDGFLVGGASLKP+FI Sbjct: 203 QEVHLAVRRWMEEKVSPAVAKSIRIIYGGSVTAANCRTLAKQPDVDGFLVGGASLKPDFI 262 Query: 243 DIIKA 247 +I A Sbjct: 263 EICNA 267 >4POC-A nrPDB Length = 254 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 149/248 (60%), Positives = 180/248 (72%), Gaps = 2/248 (0%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 +RKFFVGGNWK NG + + +++ TLN A+VP+ EVV +PP ++ + L Sbjct: 9 SRKFFVGGNWKMNGRKQSLGELIGTLNAAKVPAD--TEVVCAPPTAYIDFARQKLDPKIA 66 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 VAAQNC+ GAFTGE+S M+ + WV+LGHSERR + ES E +G KVA+ALA+G Sbjct: 67 VAAQNCYKVTNGAFTGEISPGMIKDCGATWVVLGHSERRHVFGESDELIGQKVAHALAEG 126 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L VIAC+GE L+EREAG T VV QTK IAD V +WS VV+AYEPVWAIGTGK A+P Q Sbjct: 127 LGVIACIGEKLDEREAGITEKVVFEQTKVIADNVKDWSKVVLAYEPVWAIGTGKTATPQQ 186 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEF 241 AQEVH++LR WL NVS VA +TRIIYGGSV G CKEL Q DVDGFLVGGASLKPEF Sbjct: 187 AQEVHEKLRGWLKSNVSDAVAQSTRIIYGGSVTGATCKELASQPDVDGFLVGGASLKPEF 246 Query: 242 IDIIKAAE 249 +DII A + Sbjct: 247 VDIINAKQ 254 >1SW7-A nrPDB Length = 248 Score = 380 bits (976), Expect = e-106, Method: Composition-based stats. Identities = 148/245 (60%), Positives = 181/245 (73%), Gaps = 2/245 (0%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 RKFFVGGNWK NG + + ++++TLN A++ + EVV P ++L + L + V Sbjct: 4 RKFFVGGNWKMNGDKKSLGELIHTLNGAKLSAD--TEVVCGAPSIYLDFARQKLDAKIGV 61 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQNC+ GAFTGE+S M+ ++ WVILGHSERR + ES E +G KVA+ALA+GL Sbjct: 62 AAQNCYKVPKGAFTGEISPAMIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGL 121 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 VIAC+GE L+EREAG T VV QTKAIAD V +WS VV+AYEPVWAIGTG ++P QA Sbjct: 122 GVIACIGEKLDEREAGITEKVVFEQTKAIADNVKDWSKVVLAYEPVWAIGTGNSSTPQQA 181 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH++LR WL +VS VA +TRIIYGGSV GGNCKEL Q DVDGFLVGGASLKPEF+ Sbjct: 182 QEVHEKLRGWLKSHVSDAVAQSTRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEFV 241 Query: 243 DIIKA 247 DII A Sbjct: 242 DIINA 246 >1MO0-A nrPDB Length = 275 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 138/251 (54%), Positives = 169/251 (67%), Gaps = 2/251 (0%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 + RKFFVGGNWK NG V IV LN + S V+VVV+PP +L KS L++ Sbjct: 21 LTRKFFVGGNWKMNGDYASVDGIVTFLNASADNSS--VDVVVAPPAPYLAYAKSKLKAGV 78 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 VAAQNC+ GAFTGE+S M+ +L + WVILGHSERR + ES + +K +AL Sbjct: 79 LVAAQNCYKVPKGAFTGEISPAMIKDLGLEWVILGHSERRHVFGESDALIAEKTVHALEA 138 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 G+KV+ C+GE LEEREAG T DV Q +AI D+ +W N+VIAYEPVWAIGTGK AS Sbjct: 139 GIKVVFCIGEKLEEREAGHTKDVNFRQLQAIVDKGVSWENIVIAYEPVWAIGTGKTASGE 198 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVH+ +R +L + VS VA TRIIYGGSV N ELG + D+DGFLVGGASLKP+ Sbjct: 199 QAQEVHEWIRAFLKEKVSPAVADATRIIYGGSVTADNAAELGKKPDIDGFLVGGASLKPD 258 Query: 241 FIDIIKAAEVK 251 F+ II A Sbjct: 259 FVKIINARSTA 269 >5EYW-A nrPDB Length = 249 Score = 375 bits (964), Expect = e-105, Method: Composition-based stats. Identities = 131/246 (53%), Positives = 170/246 (69%), Gaps = 2/246 (0%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 RKFFVGGNWK NG + I++ + P EVVV P +L + + ++ + Sbjct: 5 RKFFVGGNWKMNGDKAAIDGIISFMKTG--PLSPNTEVVVGCPQCYLMYTREHMPANIGI 62 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQNC+ GAFTGE+S M+ + WVILGHSERR + E + + +KV +AL GL Sbjct: 63 AAQNCYKVAKGAFTGEISPAMVKDCGCEWVILGHSERRNVFGEPDQLISEKVGHALEAGL 122 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 KVI C+GE LE+RE T +VV AQ KA+ +++WS VV+AYEPVWAIGTGK ASP QA Sbjct: 123 KVIPCIGEKLEDREGNRTQEVVFAQMKALLPNISDWSRVVLAYEPVWAIGTGKTASPEQA 182 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPEFI 242 QEVH +LR+WL NV+A+VA +TRIIYGGSV+ GNC+EL + D+DGFLVGGA+LKP+F+ Sbjct: 183 QEVHADLRQWLRDNVNAEVAESTRIIYGGSVSAGNCQELAKKGDIDGFLVGGAALKPDFV 242 Query: 243 DIIKAA 248 II A Sbjct: 243 QIINAR 248 >4OHQ-A nrPDB Length = 256 Score = 370 bits (951), Expect = e-103, Method: Composition-based stats. Identities = 157/254 (61%), Positives = 190/254 (74%), Gaps = 3/254 (1%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 + KFFVGGNWKCNGT + + K+++ LN A + + V+VVVSPP+V++ VKS+L Sbjct: 4 SGKFFVGGNWKCNGTKDSIAKLISDLNSATLEAD--VDVVVSPPFVYIDQVKSSLTDRID 61 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 ++ QN WV KGGAFTGE+S E L +L WVILGHSERR ++ E EF+G K AYAL++G Sbjct: 62 ISGQNSWVGKGGAFTGEISVEQLKDLGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEG 121 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L VIAC+GE LEEREAG T DV AQ KA AD V +W N+V+AYEPVWAIGTGKVASP Q Sbjct: 122 LGVIACIGEKLEEREAGKTFDVCFAQLKAFADAVPSWDNIVVAYEPVWAIGTGKVASPQQ 181 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PE 240 AQEVH +R WL KNVS +VA+ TRIIYGGSVNGGN EL + D+DGFLVGGASLK PE Sbjct: 182 AQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPE 241 Query: 241 FIDIIKAAEVKKSA 254 F I+ + KK A Sbjct: 242 FATIVNSVTSKKVA 255 >3KRS-A nrPDB Length = 271 Score = 363 bits (933), Expect = e-101, Method: Composition-based stats. Identities = 119/253 (47%), Positives = 166/253 (65%), Gaps = 7/253 (2%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD- 59 M+RK+FVGGN+KCNGT E +K ++++ + + + EV V P + + LVK +D Sbjct: 22 MSRKYFVGGNFKCNGTKESLKTLIDSFKQVESSNS---EVYVFPTSLHISLVKEFFGNDH 78 Query: 60 ---FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAY 116 F + +QN GAFTGEVS EML ++D+ ++GHSERR +E+ + V +KV Sbjct: 79 PGVFKIGSQNISCTGNGAFTGEVSCEMLKDMDVDCSLVGHSERRQYYSETDQIVNNKVKK 138 Query: 117 ALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKV 176 L GLK++ C+GE+L ERE G T DV+ Q V++ SN+VIAYEP+WAIGTG V Sbjct: 139 GLENGLKIVLCIGESLSERETGKTNDVIQKQLTEALKDVSDLSNLVIAYEPIWAIGTGVV 198 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 A+P QAQE H +R+++ + + V++ RIIYGGSV NC EL AD+DGFLVGGAS Sbjct: 199 ATPGQAQEAHAFIREYVTRMYNPQVSSNLRIIYGGSVTPDNCNELIKCADIDGFLVGGAS 258 Query: 237 LKPEFIDIIKAAE 249 LKP F II++A+ Sbjct: 259 LKPTFAKIIESAQ 271 >2VXN-A nrPDB Length = 251 Score = 359 bits (921), Expect = e-100, Method: Composition-based stats. Identities = 133/249 (53%), Positives = 171/249 (68%), Gaps = 6/249 (2%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDFFV 62 + NWKCNGT ++K+V NE + V+ VV+P +V +PLV++ LR + + Sbjct: 6 QPIAAANWKCNGTTASIEKLVQVFNEHTISHD--VQCVVAPTFVHIPLVQAKLRNPKYVI 63 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 +AQN + K GAFTGEVS +L ++ + WVILGHSERR E+ E V KV+ A QG Sbjct: 64 SAQNA-IAKSGAFTGEVSMPILKDIGVHWVILGHSERRTYYGETDEIVAQKVSEACKQGF 122 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPA 180 VIAC+GETL++REA T VV +QT AIA ++T W+ VV+AYEPVWAIGTGKVA+P Sbjct: 123 MVIACIGETLQQREANQTAKVVLSQTSAIAAKLTKDAWNQVVLAYEPVWAIGTGKVATPE 182 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVH LRKW+++N+ DVAA RI+YGGSVN N L + D++GFLVGGASLKPE Sbjct: 183 QAQEVHLLLRKWVSENIGTDVAAKLRILYGGSVNAANAATLYAKPDINGFLVGGASLKPE 242 Query: 241 FIDIIKAAE 249 F DII A Sbjct: 243 FRDIIDATR 251 >5CG7-A nrPDB Length = 271 Score = 358 bits (919), Expect = 1e-99, Method: Composition-based stats. Identities = 131/249 (52%), Positives = 169/249 (67%), Gaps = 6/249 (2%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDFFV 62 + V NWKCNGT ++K+V LNE Q+ V+ VV+P +V +P+V++ L + V Sbjct: 26 QPIVAANWKCNGTTASIEKLVQVLNEHQIDHD--VQCVVAPSFVHIPMVQAKLCNPKYAV 83 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 +A+N + K GAFTGEVS +L +L + WVILGHSERR E+ V KVA A QG Sbjct: 84 SAENA-IAKSGAFTGEVSMPILKDLGVSWVILGHSERRTYYGETDGVVAQKVADAYNQGF 142 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASPA 180 VIAC+GETL++REA T VV +QT AIA ++ WS +V+AYEPVWAIGTGKVA+P Sbjct: 143 MVIACIGETLQQREANQTAKVVLSQTAAIAAKLPKEAWSQIVLAYEPVWAIGTGKVATPE 202 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQEVH LR+W+++ + VA RI+YGGSV GN K L + D++GFLVGGASLKPE Sbjct: 203 QAQEVHALLRQWVSEKIGNGVATKLRILYGGSVTAGNAKTLYMKPDINGFLVGGASLKPE 262 Query: 241 FIDIIKAAE 249 F DII A Sbjct: 263 FRDIIDATR 271 >1LZO-A nrPDB Length = 248 Score = 358 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 117/248 (47%), Positives = 155/248 (62%), Gaps = 1/248 (0%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDF 60 MARK+FV NWKCNGT E +K + N+ N ++VVV P V + L+S F Sbjct: 1 MARKYFVAANWKCNGTLESIKSLTNSFNNLDFDPS-KLDVVVFPVSVHYDHTRKLLQSKF 59 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 QN G++TGEVSAE+ +L+I +VI+GH ERR +E+ E V +K+ +L Sbjct: 60 STGIQNVSKFGNGSYTGEVSAEIAKDLNIEYVIIGHFERRKYFHETDEDVREKLQASLKN 119 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 LK + C GE+LE+RE T++V+ Q KA D + N+ NV++ YEP+WAIGTGK A+P Sbjct: 120 NLKAVVCFGESLEQREQNKTIEVITKQVKAFVDLIDNFDNVILVYEPLWAIGTGKTATPE 179 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQ VH E+RK + A RI+YGGSVN NC L Q D+DGFLVG ASLK Sbjct: 180 QAQLVHKEIRKIVKDTCGEKQANQIRILYGGSVNTENCSSLIQQEDIDGFLVGNASLKES 239 Query: 241 FIDIIKAA 248 F+DIIK+A Sbjct: 240 FVDIIKSA 247 >1I45-A nrPDB Length = 248 Score = 356 bits (914), Expect = 5e-99, Method: Composition-based stats. Identities = 127/249 (51%), Positives = 172/249 (69%), Gaps = 3/249 (1%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SD 59 MAR FFVGGN+K NG+ + +K+IV LN A +P + VEVV+ PP +L S ++ Sbjct: 1 MARTFFVGGNFKLNGSKQSIKEIVERLNTASIP--ENVEVVICPPATYLDYSVSLVKKPQ 58 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 V AQN ++K GAFTGE S + + ++ +VILGHSERR+ +E +F+ DK +AL Sbjct: 59 VTVGAQNAYLKASGAFTGENSVDQIKDVGAKYVILGHSERRSYFHEDDKFIADKTKFALG 118 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASP 179 QG+ VI C+GETLEE++AG T+DVV Q A+ + V +++NVV+AYEPVWAIGTG A+P Sbjct: 119 QGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDFTNVVVAYEPVWAIGTGLAATP 178 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 AQ++H +RK+LA + A+ RI+YGGS NG N +ADVDGFLVGGASLKP Sbjct: 179 EDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKP 238 Query: 240 EFIDIIKAA 248 EF+DII + Sbjct: 239 EFVDIINSR 247 >4MKN-A nrPDB Length = 270 Score = 355 bits (912), Expect = 9e-99, Method: Composition-based stats. Identities = 142/252 (56%), Positives = 179/252 (71%), Gaps = 4/252 (1%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDF 60 + KFFVGGNWKCNG+ V K+V+ LN +P V+VVV+PP++++ V L R + Sbjct: 18 SAKFFVGGNWKCNGSVANVAKLVDELNAGTIP--RGVDVVVAPPFIYIDYVMQHLDRDKY 75 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 ++AQN W+ GAFTGEVSAE L + +PWVILGHSERR++ ES+E V K ++ALA Sbjct: 76 QLSAQNAWIGGNGAFTGEVSAEQLTDFGVPWVILGHSERRSLFGESNEVVAKKTSHALAA 135 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPA 180 GL VIAC+GETLE+R +GS V+ AQ A+ D V +W+ VV+AYEPVWAIGTG VASP Sbjct: 136 GLGVIACIGETLEQRNSGSVFKVLDAQMDALVDEVKDWTKVVLAYEPVWAIGTGVVASPE 195 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-P 239 QAQEVH LR++ AK + A VA RIIYGGSV+ NCK+L Q D+DGFLVGGASLK Sbjct: 196 QAQEVHAYLRQYCAKKLGAAVADKLRIIYGGSVSDTNCKDLSKQEDIDGFLVGGASLKGA 255 Query: 240 EFIDIIKAAEVK 251 F+ I AA K Sbjct: 256 AFVTICNAAGPK 267 >1CI1-A nrPDB Length = 251 Score = 353 bits (907), Expect = 3e-98, Method: Composition-based stats. Identities = 130/254 (51%), Positives = 169/254 (66%), Gaps = 8/254 (3%) Query: 1 MARKF--FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR- 57 MA K NWKCNG+ + ++ TLN A V+ VV+P ++ +P+ K+ L Sbjct: 1 MASKPQPIAAANWKCNGSESLLVPLIETLNAATFDHD--VQCVVAPTFLHIPMTKARLTN 58 Query: 58 SDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYA 117 F +AAQN + + GAFTGEVS ++L + I WV+LGHSERR E++E V +KVA A Sbjct: 59 PKFQIAAQNA-ITRSGAFTGEVSLQILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQA 117 Query: 118 LAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGK 175 A G VI CVGET EEREAG T VV Q A+A +++ WS VVIAYEPVWAIGTGK Sbjct: 118 CAAGFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGK 177 Query: 176 VASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA 235 VA+P QAQEVH+ LR+W+ + D+AA RI+YGGSV N + L D++GFLVGGA Sbjct: 178 VATPQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGA 237 Query: 236 SLKPEFIDIIKAAE 249 SLKPEF++II+A + Sbjct: 238 SLKPEFVEIIEATK 251 >3Q37-A nrPDB Length = 251 Score = 346 bits (889), Expect = 4e-96, Method: Composition-based stats. Identities = 129/254 (50%), Positives = 172/254 (67%), Gaps = 8/254 (3%) Query: 1 MARKF--FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR- 57 MA K NWKCNG+ + + ++++ N + V+ VV+P ++ +P+ K+ L Sbjct: 1 MASKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHD--VQCVVAPTFLHIPMTKARLTN 58 Query: 58 SDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYA 117 F +AAQN + + GAFTGEVS ++L + I WV+LGHSERRA E++E V DKVA A Sbjct: 59 PKFQIAAQNA-ITRSGAFTGEVSLQILKDYGISWVVLGHSERRAYYGETNEIVADKVAAA 117 Query: 118 LAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGK 175 +A G VI CVGET EEREAG T VV Q A+A +++ WS VVIAYEPVWAIGTGK Sbjct: 118 VASGFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGK 177 Query: 176 VASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA 235 VA+P QAQEVH+ LR+W+ + D+AA RI+YGGSV N + L D++GFLVGGA Sbjct: 178 VATPQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGA 237 Query: 236 SLKPEFIDIIKAAE 249 SLKPEF++II+A + Sbjct: 238 SLKPEFVEIIEATK 251 >1B9B-A nrPDB Length = 255 Score = 340 bits (873), Expect = 3e-94, Method: Composition-based stats. Identities = 113/252 (44%), Positives = 148/252 (58%), Gaps = 4/252 (1%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-D 59 + RK + GNWK + T E KK V+ L ++ E+VV PP+ L V L + Sbjct: 1 ITRKLILAGNWKMHKTISEAKKFVSLLVNELHDVKE-FEIVVCPPFTALSEVGEILSGRN 59 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 + AQN + + GAFTGE+S ML + + +VI+GHSERR I E EF+ KV L Sbjct: 60 IKLGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLE 119 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTGKVA 177 +G+ I CVGETLEERE G T VV Q + + VVIAYEPVWAIGTG+VA Sbjct: 120 KGMTPILCVGETLEEREKGLTFCVVEKQVREGFYGLDKEEAKRVVIAYEPVWAIGTGRVA 179 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 +P QAQEVH +RK L++ + A + RI+YGGS+ N L Q D+DG LVGGASL Sbjct: 180 TPQQAQEVHAFIRKLLSEMYDEETAGSIRILYGGSIKPDNFLGLIVQKDIDGGLVGGASL 239 Query: 238 KPEFIDIIKAAE 249 K FI++ + Sbjct: 240 KESFIELARIMR 251 >1KV5-A nrPDB Length = 250 Score = 339 bits (869), Expect = 8e-94, Method: Composition-based stats. Identities = 128/249 (51%), Positives = 168/249 (67%), Gaps = 6/249 (2%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFV 62 + NWKCNG+ + + ++++ N + V+ VV+ +V L + K L F + Sbjct: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKFVI 62 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQN + K GAFTGEVS +L + + W++LGHSERRA E++E V DKVA A+A G Sbjct: 63 AAQNA-IAKSGAFTGEVSLPILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 121 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASPA 180 VIAC+GETL+ERE+G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+P Sbjct: 122 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 181 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQE H + W++ + ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLKPE Sbjct: 182 QAQEAHALISSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 241 Query: 241 FIDIIKAAE 249 F+DIIKA + Sbjct: 242 FVDIIKATQ 250 >3PF3-A nrPDB Length = 257 Score = 338 bits (868), Expect = 1e-93, Method: Composition-based stats. Identities = 123/251 (49%), Positives = 167/251 (66%), Gaps = 7/251 (2%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLV-KSTLRSDF 60 AR+ F+GGN+KCNG+ + +K V + ++P D V+VV++P V L + Sbjct: 3 ARRPFIGGNFKCNGSLDFIKSHVAAIAAHKIP--DSVDVVIAPSAVHLSTAIAANTSKQL 60 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 +AAQN +++ GA+TGE S EML ++ + VI+GHSERR I+ E+ E K AL + Sbjct: 61 RIAAQNVYLEGNGAWTGETSVEMLQDMGLKHVIVGHSERRRIMGETDEQSAKKAKRALEK 120 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN----WSNVVIAYEPVWAIGTGKV 176 G+ VI CVGETL+ER+A TM+V AQ +A+ + W VVIAYEPVW+IGTG V Sbjct: 121 GMTVIFCVGETLDERKANRTMEVNIAQLEALGKELGESKMLWKEVVIAYEPVWSIGTGVV 180 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 A+P QA+EVH LRKW A+ V+A+ A RIIYGGS NG NC++LG ++DGFLVGGAS Sbjct: 181 ATPEQAEEVHVGLRKWFAEKVAAEGAQHIRIIYGGSANGSNCEKLGQCPNIDGFLVGGAS 240 Query: 237 LKPEFIDIIKA 247 LKPEF+ +I Sbjct: 241 LKPEFMTMIDI 251 >1TMH-A nrPDB Length = 254 Score = 333 bits (855), Expect = 4e-92, Method: Composition-based stats. Identities = 118/255 (46%), Positives = 150/255 (58%), Gaps = 5/255 (1%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD-FF 61 R V GNWK NG+ V ++V+ L + ++ V ++PP +++ + K Sbjct: 2 RHPLVMGNWKLNGSRHMVHELVSNLRK-ELAGVAGCAVAIAPPEMYIDMAKREAEGSHIM 60 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQN + GAFTGE SA ML ++ ++I+GHSERR ES E + K A QG Sbjct: 61 LGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQG 120 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIAD--RVTNWSNVVIAYEPVWAIGTGKVASP 179 L + C+GET E EAG T +V A Q A+ + VIAYEPVWAIGTGK A+P Sbjct: 121 LTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATP 180 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 AQAQ VH +R +A V A++A I YGGSVN N EL Q DVDGFLVGGASLKP Sbjct: 181 AQAQAVHKFIRDHIA-KVDANIAEQVIIQYGGSVNASNAAELFAQHDVDGFLVGGASLKP 239 Query: 240 EFIDIIKAAEVKKSA 254 EF+DII AAE K A Sbjct: 240 EFVDIINAAEAAKQA 254 >5VWN-A nrPDB Length = 246 Score = 333 bits (854), Expect = 5e-92, Method: Composition-based stats. Identities = 124/248 (50%), Positives = 158/248 (63%), Gaps = 11/248 (4%) Query: 3 RKFFVGGNWKCN-GTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFF 61 R FFVGGNWK N T +E +K+V LN A+V VEVVV+ P+VFLP ++ LR D+ Sbjct: 2 RTFFVGGNWKANPKTVQEAEKLVEMLNGAKVEGN--VEVVVAAPFVFLPTLQQKLRKDWK 59 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 V+A+N + K G + M+ + I W ILGHSERR IL E EF+ K +AL G Sbjct: 60 VSAENVFTKPNG------TVPMIKSFGIEWTILGHSERRDILKEDDEFLAAKAKFALENG 113 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASP 179 +K+I C GE L EREAG + V+AQ + + + W +VVIAYEP+WAIGTGKVAS Sbjct: 114 MKIIYCCGEHLSEREAGKASEFVSAQIEKMIPAIPAGKWDDVVIAYEPIWAIGTGKVAST 173 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 AQE+ +R LA V AD+A RI+YGGSV NC EL DVDGFLVGGASL+ Sbjct: 174 QDAQEMCKVIRDILAAKVGADIANKVRILYGGSVKPNNCNELAACPDVDGFLVGGASLEA 233 Query: 240 EFIDIIKA 247 FI+I+ + Sbjct: 234 GFINIVNS 241 >5UPR-A nrPDB Length = 265 Score = 331 bits (850), Expect = 1e-91, Method: Composition-based stats. Identities = 138/257 (53%), Positives = 177/257 (68%), Gaps = 10/257 (3%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR-SDF 60 AR+ FVGGNWKCNGT + +++V+ LN A V S + V+VVV+PP +F+ V+ +LR Sbjct: 7 ARRGFVGGNWKCNGTTAKTQELVDMLNSAPV-SFEQVDVVVAPPSLFISQVQDSLRQPRV 65 Query: 61 FVAAQNCWVK-KGGAFTGEVSAEMLVNLDIPWVILGHSERRAILN----ESSEFVGDKVA 115 VAAQ+ + GAFTGE+S +M+ +IPWV+LGHSERRA ES++ V KV Sbjct: 66 QVAAQDSSTQQAYGAFTGELSPKMIKEKNIPWVVLGHSERRAGFGGQPGESNQVVAKKVR 125 Query: 116 YALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN---WSNVVIAYEPVWAIG 172 AL +GL VI C+GETLEERE+G T V++ Q +A+ V W ++VIAYEPVWAIG Sbjct: 126 AALNEGLSVILCIGETLEERESGQTQKVLSEQLEAVRQAVPEADAWKSIVIAYEPVWAIG 185 Query: 173 TGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLV 232 TGK A+ A AQE H ++R WLA+ VS VA TR+IYGGSV G N KEL DVDGFLV Sbjct: 186 TGKTATAALAQETHRDIRNWLAQAVSPKVAEATRVIYGGSVKGSNAKELFEGEDVDGFLV 245 Query: 233 GGASLKPEFIDIIKAAE 249 GGASL +F+ II AA+ Sbjct: 246 GGASLTGDFVSIIDAAK 262 >1BTM-A nrPDB Length = 252 Score = 330 bits (846), Expect = 4e-91, Method: Composition-based stats. Identities = 106/249 (42%), Positives = 143/249 (57%), Gaps = 5/249 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLP-LVKSTLRSDFF 61 RK + GNWK + T E + V + VP D V VV P++FL LV++ +D Sbjct: 1 RKPIIAGNWKMHKTLAEAVQFVEDVK-GHVPPADEVISVVCAPFLFLDRLVQAADGTDLK 59 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQ GA+TGEVS ML +L + +VILGHSERR + E+ E V KV A +G Sbjct: 60 IGAQTMHFADQGAYTGEVSPVMLKDLGVTYVILGHSERRQMFAETDETVNKKVLAAFTRG 119 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASP 179 L I C GE+LEEREAG T VVA+Q + +T VIAYEP+WAIGTGK ++P Sbjct: 120 LIPIICCGESLEEREAGQTNAVVASQVEKALAGLTPEQVKQAVIAYEPIWAIGTGKSSTP 179 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 A V +R +++ + A RI YGGSV N ++ Q +DG LVGGASL+P Sbjct: 180 EDANSVCGHIRSVVSRLFGPEAAEAIRIQYGGSVKPDNIRDFLAQQQIDGPLVGGASLEP 239 Query: 240 -EFIDIIKA 247 F+ +++A Sbjct: 240 ASFLQLVEA 248 >2V5B-A nrPDB Length = 244 Score = 329 bits (845), Expect = 5e-91, Method: Composition-based stats. Identities = 122/254 (48%), Positives = 158/254 (62%), Gaps = 15/254 (5%) Query: 1 MARKF--FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLR- 57 MA K NWKCNG+ + ++ TLN A V+ VV+P ++ +P+ K+ L Sbjct: 1 MASKPQPIAAANWKCNGSESLLVPLIETLNAATFDHD--VQCVVAPTFLHIPMTKARLTN 58 Query: 58 SDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYA 117 F +AAQN + L + I WV+LGHSERR E++E V +KVA A Sbjct: 59 PKFQIAAQNAGNAD--------ALASLKDYGISWVVLGHSERRLYYGETNEIVAEKVAQA 110 Query: 118 LAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGK 175 A G VI CVGET EEREAG T VV Q A+A +++ WS VVIAYEPVWAIGTGK Sbjct: 111 CAAGFHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRVVIAYEPVWAIGTGK 170 Query: 176 VASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA 235 VA+P QAQEVH+ LR+W+ + D+AA RI+YGGSV N + L D++GFLVGGA Sbjct: 171 VATPQQAQEVHELLRRWVRSKLGTDIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGA 230 Query: 236 SLKPEFIDIIKAAE 249 SLKPEF++II+A + Sbjct: 231 SLKPEFVEIIEATK 244 >4Y8F-A nrPDB Length = 251 Score = 329 bits (843), Expect = 9e-91, Method: Composition-based stats. Identities = 107/248 (43%), Positives = 140/248 (56%), Gaps = 6/248 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFF 61 R + GNWK + T +E K+V L + EVVV P +V L VK + + Sbjct: 5 RTPIIAGNWKMHYTIDEAVKLVEELKPLVKDA--KCEVVVCPTFVCLDAVKKAVEGTNIK 62 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 V AQN ++ GAFTGE++ ML ++I +VI+GHSERR NE+ E KV A A Sbjct: 63 VGAQNMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHN 122 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASP 179 L I C GETLE+RE G+T DV+ AQ A + +T VVIAYEP+WAIGTGK A+ Sbjct: 123 LTPILCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATS 182 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL-K 238 QA E +R +A+ +VA RI YGGSV E ++D+DG LVGGASL Sbjct: 183 DQANETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASLVA 242 Query: 239 PEFIDIIK 246 +F I+ Sbjct: 243 ADFAQIVN 250 >4Y96-A nrPDB Length = 255 Score = 323 bits (829), Expect = 3e-89, Method: Composition-based stats. Identities = 117/251 (46%), Positives = 147/251 (58%), Gaps = 6/251 (2%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD-F 60 RK FV GNWK N T E K + + + + D V V V PPY +L V L+ Sbjct: 6 TRKKFVAGNWKMNTTLAEAKALGAAVAKGV--TDDRVTVAVFPPYPWLTAVGEVLKGSPV 63 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 + AQ+ +K GAFTGEVS ML+ + ++GHSERR I+ ES F+ KV AL + Sbjct: 64 ALGAQDVSSEKKGAFTGEVSPAMLLETGCKYALIGHSERRHIIGESETFINHKVHTALEE 123 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVAS 178 GL V+ C+GETL ERE G V Q A +T+ + +VIAYEPVWAIGTGKVA+ Sbjct: 124 GLSVVLCMGETLAERERGLQERVFQRQVYAACAGLTDEQFGRIVIAYEPVWAIGTGKVAT 183 Query: 179 PAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK 238 P QAQE H +R L +A +T I+YGGSV N L Q DVDG LVGGASLK Sbjct: 184 PEQAQEAHAFVRSKLRLLYGDKIADSTPIVYGGSVTPDNTVGLMSQPDVDGALVGGASLK 243 Query: 239 PE-FIDIIKAA 248 + F+ I+KAA Sbjct: 244 ADSFLAIVKAA 254 >3UWW-A nrPDB Length = 261 Score = 321 bits (824), Expect = 1e-88, Method: Composition-based stats. Identities = 104/254 (40%), Positives = 142/254 (55%), Gaps = 9/254 (3%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPL----VKSTLRS 58 R + GNWK N T +E K VN L +P VE V+ P + L VK Sbjct: 10 RTPIIAGNWKMNKTVQEAKDFVNALP--TLPDSKEVESVICAPAIQLDALTTAVKEGKAQ 67 Query: 59 DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYAL 118 + AQN + + GAFTGE S L +L + +V++GHSERR + +E+ E + K Sbjct: 68 GLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRELFHETDEEINKKAHAIF 127 Query: 119 AQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKV 176 G+ I CVGET EERE+G DVV Q K ++ +VVIAYEP+WAIGTGK Sbjct: 128 KHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSEDQLKSVVIAYEPIWAIGTGKS 187 Query: 177 ASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGAS 236 ++ A E+ +R+ +A S +V+ TRI YGGSV N KE Q D+DG LVGGAS Sbjct: 188 STSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKPNNIKEYMAQTDIDGALVGGAS 247 Query: 237 LK-PEFIDIIKAAE 249 LK +F+ +++ A+ Sbjct: 248 LKVEDFVQLLEGAK 261 >1M6J-A nrPDB Length = 261 Score = 320 bits (820), Expect = 4e-88, Method: Composition-based stats. Identities = 132/259 (50%), Positives = 172/259 (66%), Gaps = 10/259 (3%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLN-EAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-- 58 A KF VGGNWKCNGT ++ + + VEV+V P++++P V+ L Sbjct: 3 AGKFVVGGNWKCNGTLASIETLTKGVAASVDAELAKKVEVIVGVPFIYIPKVQQILAGEA 62 Query: 59 ---DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVA 115 + V+A+N W K GA+TGEV MLV+ +P+VILGHSERR I +ES+E V +KV Sbjct: 63 NGANILVSAENAWTK-SGAYTGEVHVGMLVDCQVPYVILGHSERRQIFHESNEQVAEKVK 121 Query: 116 YALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGT 173 A+ GLKVIAC+GET +R A T +VVAAQ KAI + ++ W N+++AYEPVWAIGT Sbjct: 122 VAIDAGLKVIACIGETEAQRIANQTEEVVAAQLKAINNAISKEAWKNIILAYEPVWAIGT 181 Query: 174 GKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVG 233 GK A+P QAQEVH +RKW+ +N+S +VA TRI YGGSVN NC EL +AD+DGFLVG Sbjct: 182 GKTATPDQAQEVHQYIRKWMTENISKEVAEATRIQYGGSVNPANCNELAKKADIDGFLVG 241 Query: 234 GASLK-PEFIDIIKAAEVK 251 GASL +F II + K Sbjct: 242 GASLDAAKFKTIINSVSEK 260 >1TRI-A nrPDB Length = 243 Score = 319 bits (817), Expect = 8e-88, Method: Composition-based stats. Identities = 120/249 (48%), Positives = 159/249 (63%), Gaps = 13/249 (5%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFFV 62 + NWKCNG+ + + ++++ N + V+ VV+ +V L + K L F + Sbjct: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHD--VQCVVASTFVHLAMTKERLSHPKFVI 62 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AAQN + L + + W++LGHSERRA E++E V DKVA A+A G Sbjct: 63 AAQNAGNAD--------ALASLKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF 114 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASPA 180 VIAC+GETL+ERE+G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+P Sbjct: 115 MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGTGKVATPQ 174 Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE 240 QAQE H +R W++ + ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLKPE Sbjct: 175 QAQEAHALIRSWVSSKIGADVAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE 234 Query: 241 FIDIIKAAE 249 F+DIIKA + Sbjct: 235 FVDIIKATQ 243 >5IBX-C nrPDB Length = 255 Score = 318 bits (815), Expect = 2e-87, Method: Composition-based stats. Identities = 102/250 (40%), Positives = 142/250 (56%), Gaps = 5/250 (2%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-D 59 M+RK F+ GNWK N EE K V + ++PS D+VE ++ P + L V + + + Sbjct: 4 MSRKPFIAGNWKMNKNPEEAKAFVEAVAS-KLPSSDLVEAGIAAPALDLTTVLAVAKGSN 62 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 VAAQNC+ + GAFTGE S ++L + +V++GHSERR +E+ E + K A Sbjct: 63 LKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDYFHETDEDINKKAKAIFA 122 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVA 177 G+ I C GE+LE EAG + V AQ A +T + VIAYEP+WAIGTGK A Sbjct: 123 NGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQVAASVIAYEPIWAIGTGKSA 182 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 S AQ++ +R +A + +VA R+ YGGSV N DVDG LVGGASL Sbjct: 183 SQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPENVASYMACPDVDGALVGGASL 242 Query: 238 KPE-FIDIIK 246 + E F+ ++ Sbjct: 243 EAESFLALLD 252 >4Y9A-A nrPDB Length = 261 Score = 317 bits (812), Expect = 3e-87, Method: Composition-based stats. Identities = 105/252 (41%), Positives = 133/252 (52%), Gaps = 7/252 (2%) Query: 2 ARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQ-DVVEVVVSPPYVFLPLVKSTLRS-- 58 R + GNWK N E V L A D VEV V P+ L V++ + Sbjct: 6 TRTPLMAGNWKMNLNHLEAIAHVQKLAFALADKDYDAVEVAVLAPFTDLRSVQTLVDGDK 65 Query: 59 -DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYA 117 AQ+ GGA+TGE+S ML L +V +GHSERR E+ E V KV A Sbjct: 66 LKIKYGAQDISAHDGGAYTGEISGPMLAKLKCTYVAVGHSERRQYHAETDEIVNAKVKAA 125 Query: 118 LAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTGK 175 GL I CVGE L+ REAG+ ++ AQ + + +VVIAYEPVWAIGTGK Sbjct: 126 YKHGLTPILCVGEELDVREAGNHVEHTLAQVEGGLKDLAAEQAESVVIAYEPVWAIGTGK 185 Query: 176 VASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGA 235 V AQEV +R LA+ S ++A RI YGGSV GN E+ + D+DG LVGGA Sbjct: 186 VCGADDAQEVCAAIRGKLAELYSQELADKVRIQYGGSVKSGNVAEIMAKPDIDGALVGGA 245 Query: 236 SLKP-EFIDIIK 246 SL EF+ I++ Sbjct: 246 SLDSDEFVKIVR 257 >1YYA-A nrPDB Length = 250 Score = 315 bits (808), Expect = 9e-87, Method: Composition-based stats. Identities = 101/250 (40%), Positives = 135/250 (54%), Gaps = 6/250 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL-RSDFF 61 R+ V GNWK + T E + L P Q E V P + LP+ K L + Sbjct: 2 RRVLVAGNWKMHKTPSEARVWFAELKRLLPPLQS--EAAVLPAFPILPVAKEVLAETQVG 59 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 AQ+ K GA+TGEVSA ML +L + I+GHSERR E+ V +K L +G Sbjct: 60 YGAQDVSAHKEGAYTGEVSARMLSDLGCRYAIVGHSERRRYHGETDALVAEKAKRLLEEG 119 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTGKVASP 179 + I CVGE LE RE G + Q + + V +VIAYEPVWAIGTGK A+P Sbjct: 120 ITPILCVGEPLEVREKGEAVPYTLRQLRGSLEGVEPPGPEALVIAYEPVWAIGTGKNATP 179 Query: 180 AQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP 239 A+ +H +RK L++ A+ RI+YGGSVN N +L +VDG LVGGASL+ Sbjct: 180 EDAEAMHQAIRKALSERYGEAFASRVRILYGGSVNPKNFADLLSMPNVDGGLVGGASLEL 239 Query: 240 E-FIDIIKAA 248 E F+ +++ A Sbjct: 240 ESFLALLRIA 249 >2Y70-A nrPDB Length = 245 Score = 314 bits (804), Expect = 3e-86, Method: Composition-based stats. Identities = 120/251 (47%), Positives = 156/251 (62%), Gaps = 15/251 (5%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVF--LPLVKSTL-RSDF 60 + NWKCNG+ + + ++++ N + V+ VV+P + + K L F Sbjct: 5 QPIAAANWKCNGSQQSLSELIDLFNSTSINHD--VQCVVAPSWYMGAQAMTKERLSHPKF 62 Query: 61 FVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQ 120 +AAQN + L + I W++L HSERRA E++E V DKVA A+A Sbjct: 63 VIAAQNAGNAD--------ALASLKDFGISWIVLDHSERRAYYGETNEIVADKVAAAVAS 114 Query: 121 GLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVAS 178 G VIAC+GETL+ER +G T VV Q AIA ++ +W+ VVIAYEPVWAIGTGKVA+ Sbjct: 115 GFMVIACIGETLQERSSGRTAVVVLTQITAIAKKLKKADWAKVVIAYEPVWAIGTGKVAT 174 Query: 179 PAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK 238 P QAQE H +R W++ V ADVA RI+YGGSVNG N + L Q DV+GFLVGGASLK Sbjct: 175 PQQAQEAHALIRSWVSSKVGADVAGELRILYGGSVNGRNARTLYQQRDVNGFLVGGASLK 234 Query: 239 PEFIDIIKAAE 249 PEF+DIIKA E Sbjct: 235 PEFVDIIKATE 245 >5UJW-A nrPDB Length = 253 Score = 308 bits (790), Expect = 1e-84, Method: Composition-based stats. Identities = 98/246 (39%), Positives = 143/246 (58%), Gaps = 5/246 (2%) Query: 6 FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQ 65 + GNWK NG + +K++ + +++ Q + V + V P V++ V S L V Q Sbjct: 4 LIMGNWKMNGNSTSIKELCSGISQVQYDTSR-VAIAVFPSSVYVKEVISQLPEKVGVGLQ 62 Query: 66 NCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVI 125 N GA+TGE+SA ML ++ ++++GHSERR++ ES E V K+ + + + Sbjct: 63 NITFYDDGAYTGEISARMLEDIGCDYLLIGHSERRSLFAESDEDVFKKLNKIIDTTITPV 122 Query: 126 ACVGETLEEREAGSTMDVVAAQTKAIADR--VTNWSNVVIAYEPVWAIGTGKVASPAQAQ 183 C+GE+L++R++G V+A Q I + V + VVIAYEPVWAIGTG VAS Q Q Sbjct: 123 VCIGESLDDRQSGKLKQVLATQLSLILENLSVEQLAKVVIAYEPVWAIGTGVVASLEQIQ 182 Query: 184 EVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEFI 242 E H +R LA V +A +I+YGGS+ N K++ DVDG L+GGASLK EF Sbjct: 183 ETHQFIRSLLA-KVDERLAKNIKIVYGGSLKAENAKDILSLPDVDGGLIGGASLKAAEFN 241 Query: 243 DIIKAA 248 +II A Sbjct: 242 EIINQA 247 >3KXQ-A nrPDB Length = 275 Score = 306 bits (785), Expect = 5e-84, Method: Composition-based stats. Identities = 90/245 (36%), Positives = 124/245 (50%), Gaps = 3/245 (1%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFFV 62 + F+ GNWK NGT E + ++ + E ++ P L L + + Sbjct: 27 RPFIAGNWKMNGTGESLGELRAIAAGISSDLGRLFEALICVPATLLSRAFDILGGENILL 86 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 QNC G +TG++SA ML VI+GHSERR + ES V KV A GL Sbjct: 87 GGQNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWRAGL 146 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 + CVGETLEER++ +DV+ Q + N++IAYEPVWA+GTG A+ A Sbjct: 147 VALICVGETLEERKSNKVLDVLTRQLEGSLPDGATAENIIIAYEPVWAVGTGNTATSADV 206 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP-EF 241 EVH + + + A R++YGGSV N EL A V+G L+GGASLK +F Sbjct: 207 AEVHAFIHHKMHSRFGDE-GAKIRLLYGGSVKPSNAFELLSTAHVNGALIGGASLKAIDF 265 Query: 242 IDIIK 246 + I Sbjct: 266 LTICD 270 >6BVE-A nrPDB Length = 245 Score = 301 bits (770), Expect = 3e-82, Method: Composition-based stats. Identities = 93/246 (37%), Positives = 130/246 (52%), Gaps = 10/246 (4%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFF 61 RK + GNWK + T E + + + + EVV+ P+ L + L Sbjct: 5 RKIIIAGNWKMHKTQAEAQAFLQGFKPLIEDAAESREVVLCVPFTDLSGMSQQLHGGRVR 64 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 + AQN + GA+TGE+SA ML + I +V++GHSERR E+ E +V A G Sbjct: 65 LGAQNVHWEASGAYTGEISAAMLTEIGIHYVVIGHSERRQYFGETDETANLRVLAAQKAG 124 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQ 181 L I CVGE+ +R+AG T V+ Q K V + SN+VIAYEP+WAIGTG + + Sbjct: 125 LIPILCVGESKAQRDAGETEQVIVDQVKKGLVNV-DQSNLVIAYEPIWAIGTGDTCAATE 183 Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKPE- 240 A V +R+ L + I YGGSVN N E+ Q ++DG LVGGASL+P+ Sbjct: 184 ANRVIGLIREQLTN-------SQVTIQYGGSVNANNVDEIMAQPEIDGALVGGASLEPQS 236 Query: 241 FIDIIK 246 F I+ Sbjct: 237 FARIVN 242 >4X22-A nrPDB Length = 250 Score = 298 bits (764), Expect = 1e-81, Method: Composition-based stats. Identities = 97/241 (40%), Positives = 144/241 (59%), Gaps = 5/241 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD-FF 61 RK + GNWK N + +E + +++ E +V P + L V L Sbjct: 2 RKTIIAGNWKMNLSLKEAVFLAHSIREKIPSISKDKVSMVFPSTLHLENVSKILEGSSVI 61 Query: 62 VAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQG 121 V AQNC+ AFTGE S + L + + V++GHSERR L ES+ F DK+ + L Sbjct: 62 VGAQNCYHSGLAAFTGETSPDQLKEIGVKVVMVGHSERRQFLGESNFFCNDKIRFLLKNE 121 Query: 122 LKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTN--WSNVVIAYEPVWAIGTGKVASP 179 V+ CVGETL ERE+G T++V+++Q + + + +SN+++AYEPVWAIGTGKVA+P Sbjct: 122 FTVLYCVGETLSERESGKTLEVLSSQIREGLKGIDSVFFSNLILAYEPVWAIGTGKVATP 181 Query: 180 AQAQEVHDELRKWLAKNV--SADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 +QAQEVH +RK ++ ++ ++ + I+YGGSV N ++L + D+DG LVGGAS Sbjct: 182 SQAQEVHSFIRKEISGLFVGASSISESISILYGGSVKPDNIQDLLKEKDIDGGLVGGASQ 241 Query: 238 K 238 K Sbjct: 242 K 242 >1AW2-A nrPDB Length = 256 Score = 298 bits (763), Expect = 2e-81, Method: Composition-based stats. Identities = 102/241 (42%), Positives = 134/241 (55%), Gaps = 7/241 (2%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTL---RSD 59 R V GNWK NG+ E V ++N LN A++ V+V V+PP +F+ L + TL S Sbjct: 2 RHPVVMGNWKLNGSKEMVVDLLNGLN-AELEGVTGVDVAVAPPALFVDLAERTLTEAGSA 60 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 + AQN + GAFTG++S ML +I+GHSERR ES EFV K A+ Sbjct: 61 IILGAQNTDLNNSGAFTGDMSPAMLKEFGATHIIIGHSERREYHAESDEFVAKKFAFLKE 120 Query: 120 QGLKVIACVGETLEEREAGSTMDVVAAQTKAIA--DRVTNWSNVVIAYEPVWAIGTGKVA 177 GL + C+GE+ + EAG TM V A Q A+ V +IAYEP+WAIGTGK A Sbjct: 121 NGLTPVLCIGESDAQNEAGETMAVCARQLDAVINTQGVEALEGAIIAYEPIWAIGTGKAA 180 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 + AQ +H ++R +A+ S VA I YGGSV N Q D+DG LVGGA+L Sbjct: 181 TAEDAQRIHAQIRAHIAEK-SEAVAKNVVIQYGGSVKPENAAAYFAQPDIDGALVGGAAL 239 Query: 238 K 238 Sbjct: 240 D 240 >3TA6-A nrPDB Length = 267 Score = 297 bits (761), Expect = 3e-81, Method: Composition-based stats. Identities = 106/253 (41%), Positives = 137/253 (54%), Gaps = 6/253 (2%) Query: 1 MARKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQ-DVVEVVVSPPYVFLPLVKSTLRSD 59 M+RK + GNWK N E +V + + D V+V V PP+ L V++ + D Sbjct: 1 MSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDGD 60 Query: 60 ---FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAY 116 AQ+ GA+TG+VS L L +V++GHSERR NE V K A Sbjct: 61 KLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAAT 120 Query: 117 ALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRV--TNWSNVVIAYEPVWAIGTG 174 AL GL I C+GE L+ REAG+ + Q + + +VVIAYEPVWAIGTG Sbjct: 121 ALKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGTG 180 Query: 175 KVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGG 234 +VAS A AQEV +RK LA S +A T R++YGGSVN N ++ Q DVDG LVGG Sbjct: 181 RVASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGG 240 Query: 235 ASLKPEFIDIIKA 247 ASL E + A Sbjct: 241 ASLDGEHFATLAA 253 >4NVT-A nrPDB Length = 262 Score = 297 bits (761), Expect = 3e-81, Method: Composition-based stats. Identities = 94/245 (38%), Positives = 124/245 (50%), Gaps = 3/245 (1%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD-FFV 62 + V GNWK NG E + ++ ++ V+ P L TL + + Sbjct: 14 RPLVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGL 73 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 Q+ K GA TG++S EML VILGHSERR +ES++ + K A A GL Sbjct: 74 GGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGL 133 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 I CVGET ER+A +DV+ Q N +IAYEPVWAIGTG + Sbjct: 134 VAIVCVGETASERKAERALDVIGDQLSGSLPDGVTAENTIIAYEPVWAIGTGLTPTVQDV 193 Query: 183 QEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEF 241 + H +R+ L + A A R++YGGSV N EL G ADVDG LVGGASLK +F Sbjct: 194 RAAHAFMREQLIERFGAK-GAHLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAADF 252 Query: 242 IDIIK 246 + I + Sbjct: 253 LAICE 257 >4G1K-A nrPDB Length = 272 Score = 289 bits (739), Expect = 1e-78, Method: Composition-based stats. Identities = 106/247 (42%), Positives = 144/247 (58%), Gaps = 8/247 (3%) Query: 7 VGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRS-DFFVAAQ 65 V GNWK +G + ++ + + D V + V P+ +L ++ L+ +Q Sbjct: 30 VIGNWKMHGRLSGNQALLTEVAQGAQAVHDNVAIGVCVPFPYLAQAQAQLQGGRVSWGSQ 89 Query: 66 NCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVI 125 + + GA+TGEV+A M+ + I+GHSERRA ES+E V K ALA GL I Sbjct: 90 DVSAHEQGAYTGEVAAGMVAEFGAAYAIVGHSERRAYHGESNETVAAKARRALAAGLTPI 149 Query: 126 ACVGETLEEREAGSTMDVVAAQTKAIADRVT--NWSNVVIAYEPVWAIGTGKVASPAQAQ 183 CVGETL EREAG+T VV AQ A+ ++ + +V+AYEPVWAIGTGK A+ QAQ Sbjct: 150 VCVGETLAEREAGTTEQVVGAQLDAVLAVLSPDEAARIVVAYEPVWAIGTGKSATAEQAQ 209 Query: 184 EVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLKP-EFI 242 +VH LR LA A A ++YGGSV N EL GQ D+DG L+GGASLK +F+ Sbjct: 210 QVHAFLRGRLA----AKGAGHVSLLYGGSVKADNAAELFGQPDIDGGLIGGASLKSGDFL 265 Query: 243 DIIKAAE 249 I +AA+ Sbjct: 266 AICRAAK 272 >4Y90-A nrPDB Length = 247 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 92/243 (37%), Positives = 132/243 (54%), Gaps = 5/243 (2%) Query: 6 FVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQ 65 + NWK N T E + L P++ V++ V P + L + + L + Q Sbjct: 7 LLALNWKMNKTPTEARSWAEELTTKYAPAEG-VDLAVLAPALDLSALAANLPAGIAFGGQ 65 Query: 66 NCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVI 125 + + GA+TGE+SA ML + V++GHSERR +ES V K A A GL I Sbjct: 66 DVSAHESGAYTGEISAAMLKDAGASCVVVGHSERREYHDESDATVAAKARQAQANGLLPI 125 Query: 126 ACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEV 185 CVGE L+ RE G + AQ + + V ++VV+AYEPVWAIGTGK A+ A+E+ Sbjct: 126 VCVGENLDVRERGEHVPQTLAQLRGSLEGVG--ADVVVAYEPVWAIGTGKTATADDAEEL 183 Query: 186 HDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASLK-PEFIDI 244 +R L + A A R++YGGSV N E+ G+ +V+G LVGGASLK P+ + + Sbjct: 184 AAAIRGALREQYGAR-AEGIRVLYGGSVKPENIAEICGKPNVNGALVGGASLKVPDVLGM 242 Query: 245 IKA 247 + A Sbjct: 243 LDA 245 >2JGQ-A nrPDB Length = 233 Score = 217 bits (552), Expect = 5e-57, Method: Composition-based stats. Identities = 85/249 (34%), Positives = 128/249 (51%), Gaps = 26/249 (10%) Query: 4 KFFVGGNWK----CNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSD 59 N+K + +K++ E + Q V V P + L L S L Sbjct: 1 TKIAMANFKSAMPIFKSHAYLKEL-----EKTLKPQHFDRVFVFPDFFGL-LPNSFLH-- 52 Query: 60 FFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALA 119 F + QN + + GAFTGE++++ L L I +++GHSERR +L ES F+ +K + + Sbjct: 53 FTLGVQNAYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRTLLKESPSFLKEKFDFFKS 112 Query: 120 QGLKVIACVGETLEEREAG--STMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVA 177 + K++ C+GE L RE G + + ++ Q + I N+ N+V+AYEP+WAIGT K A Sbjct: 113 KNFKIVYCIGEELTTREKGFKAVKEFLSEQLENID---LNYPNLVVAYEPIWAIGTKKSA 169 Query: 178 SPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFLVGGASL 237 S H L++ L + T ++YGGSVN N KE+ G VDG L+G AS Sbjct: 170 SLEDIYLTHGFLKQILNQK--------TPLLYGGSVNTQNAKEILGIDSVDGLLIGSASW 221 Query: 238 KPE-FIDII 245 + E F II Sbjct: 222 ELENFKTII 230 >3S6D-A nrPDB Length = 310 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 57/182 (31%), Positives = 87/182 (47%), Gaps = 6/182 (3%) Query: 57 RSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAY 116 + AQ+C+ G +TGE+S L ++++ V LGH+ERRAI E+ + V K A Sbjct: 109 PPPLLLGAQDCFWDSLGPYTGEISPVCLRDMNVSIVELGHAERRAIFGETDQQVARKAAA 168 Query: 117 ALAQGLKVIACVGE-----TLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAI 171 A QGL + C+GE + G + AQ + + + + + V+ AYEPVWAI Sbjct: 169 AADQGLIPLVCIGEVSTLGPIVSEAIGRAVGECEAQIRPVLEALPRDAPVIFAYEPVWAI 228 Query: 172 GTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVDGFL 231 G + A V +R + + + RI+YGGS G G +VDG Sbjct: 229 GKPQPARVDHVGAVVSGIRSVI-ERIDRHRKGEVRILYGGSAGPGLWGPGGLGKEVDGMF 287 Query: 232 VG 233 +G Sbjct: 288 LG 289 >5CSS-A nrPDB Length = 226 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 47/180 (26%), Positives = 71/180 (39%), Gaps = 24/180 (13%) Query: 27 LNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVN 86 E P Q E++ SP L L K+ F AQ+ + GA+TG V +M+++ Sbjct: 24 FMEKFEPVQGKFELIFSPS--LLDLEKAAKCGKFRFFAQHVDAEPYGAYTGHVPMDMMID 81 Query: 87 LDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAGSTMDVVAA 146 L I IL HSERR + + + + A ++ CV E EE Sbjct: 82 LGITGSILNHSERRL----PRDTIINTLKKASKLDFTIVLCV-ENAEE------------ 124 Query: 147 QTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTR 206 A + IAYEP IG S A+ + + D ++ + S V A + Sbjct: 125 -----AKYFREYEPDFIAYEPRDLIGGDVSVSTAKPEIIEDIVKIYEGTGTSVLVGAGIK 179 >1W0M-A nrPDB Length = 226 Score = 91.1 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 54/217 (24%), Positives = 79/217 (36%), Gaps = 36/217 (16%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 R + N+K G A + + + + V +VV+P ++ L LV ++ D V Sbjct: 2 RLPILIINFKAYGEAAGKRAVELAKAAERAARELGVNIVVAPNHLELGLVSQSV--DIPV 59 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AQ V+ GGA T VS E + VIL HSE LN+ + V A + GL Sbjct: 60 YAQGADVEAGGAHTAHVSLENIKEAGGSGVILNHSEAPLKLNDLARLVAK----AKSLGL 115 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVAS---P 179 V+ C + A +A EP IGTG+ S P Sbjct: 116 DVVVCAPDPRTSLAA------------------AALGPHAVAVEPPELIGTGRAVSRYKP 157 Query: 180 AQAQEVHDELRKWLAK---------NVSADVAATTRI 207 E + + + DVAA R+ Sbjct: 158 EAIVETVGLVSRHFPEVSVITGAGIESGDDVAAALRL 194 >2H6R-A nrPDB Length = 219 Score = 82.2 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 42/186 (22%), Positives = 69/186 (37%), Gaps = 24/186 (12%) Query: 31 QVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIP 90 +V + + + V+P +V L ++ + + V AQ+ G+ TG + AE + + Sbjct: 27 KVSEESGITIGVAPQFVDLRMIVENV--NIPVYAQHIDNINPGSHTGHILAEAIKDCGCK 84 Query: 91 WVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKA 150 ++ HSE+R +L + + GL+ I C T ++ + Sbjct: 85 GTLINHSEKRMLLADIEAVINK----CKNLGLETIVC------------TNNINTS---- 124 Query: 151 IADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKWLAKNVSADVAATTRIIYG 210 V S IA EP IGTG S A + V +R N V I G Sbjct: 125 --KAVAALSPDCIAVEPPELIGTGIPVSKANPEVVEGTVRAVKEINKDVKVLCGAGISKG 182 Query: 211 GSVNGG 216 V Sbjct: 183 EDVKAA 188 >1HG3-A nrPDB Length = 225 Score = 76.8 bits (188), Expect = 8e-15, Method: Composition-based stats. Identities = 45/199 (22%), Positives = 78/199 (39%), Gaps = 26/199 (13%) Query: 3 RKFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFV 62 ++ + N+K A + + +V + V +VV+P V L ++ ++ V Sbjct: 5 KEPIIAINFKTYIEATGKRALEIAKAAEKVYKETGVTIVVAPQLVDLRMIAESVE--IPV 62 Query: 63 AAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGL 122 AQ+ K G+ TG V E + +L HSE R IL + + A GL Sbjct: 63 FAQHIDPIKPGSHTGHVLPEAVKEAGAVGTLLNHSENRMILADLEAAI----RRAEEVGL 118 Query: 123 KVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQA 182 + C + A++ V + +A EP IGTG S A+ Sbjct: 119 MTMVC------------------SNNPAVSAAVAALNPDYVAVEPPELIGTGIPVSKAKP 160 Query: 183 QEVHDELRKWLAKNVSADV 201 + + + + L K V+ +V Sbjct: 161 EVITNTV--ELVKKVNPEV 177 >1E6V-A nrPDB Length = 553 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 39/196 (19%), Positives = 74/196 (37%), Gaps = 29/196 (14%) Query: 4 KFFVGGNWKCNGTAEEVKKIVNTLNEAQVPSQDVVEVVVSPPYVFLPLVKSTLRSDFFVA 63 KF++ G WK + +E K+ + + E + ++ V PL + L S + V+ Sbjct: 27 KFYIFGGWKQSERKKEFKEWADKIVEERGVPHYNPDIGV-------PLGQRKLMS-YQVS 78 Query: 64 AQNCWVKKGG-AFTGEVSAEMLVNLDIPWVILG----HS--ERRAILNESSEFVG---DK 113 + +V+ F + + + + VI+G H ERR + E + + Sbjct: 79 GTDVFVEGDDLTFVNNAAMQQMWDDIRRTVIVGMDTAHRVLERRLGKEVTPETINEYMET 138 Query: 114 VAYALAQGLKVIACVGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIAYEPVWAIGT 173 + +AL G A V E + E G T D A + + + I Sbjct: 139 LNHALPGG----AVVQEHMVEIHPGLTWDCYAKIITGDLELADEIDDKFL-------IDI 187 Query: 174 GKVASPAQAQEVHDEL 189 K+ QA+++ + Sbjct: 188 EKLFPEEQAEQLIKAI 203 >6OKK-M nrPDB Length = 144 Score = 29.5 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 8/11 (72%), Positives = 10/11 (90%) Query: 165 YEPVWAIGTGK 175 YEP+W IG+GK Sbjct: 50 YEPLWLIGSGK 60 >3AGK-A nrPDB Length = 373 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 9/60 (15%) Query: 77 GEVSAEMLVNLDIPWVILGHSERRAILNESSEFVGDKVAYALAQGLKVIACVGETLEERE 136 GE E + + +L H ES E + + V A + G +VI V E+L E E Sbjct: 303 GEKDVEAALEMGAVKTLLIH--------ESREDLEEWVEKAKSSGAQVIV-VPESLAEAE 353 >2RUS-A nrPDB Length = 490 Score = 28.7 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 201 VAATTRIIYGG-SVNGGNCKELGGQADVDGFLVGGASLKP 239 V R ++ G SVN ++ G+ +VDG LV G +KP Sbjct: 152 VPEAYRALFDGPSVNISALWKVLGRPEVDGGLVVGTIIKP 191 >3KW2-A nrPDB Length = 257 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 20/49 (40%), Gaps = 4/49 (8%) Query: 81 AEMLVNLDIPWVIL---GHSERRAILNESSEFVGDKV-AYALAQGLKVI 125 E LV + + V+ HSERR I E E + +L VI Sbjct: 96 LEKLVEIGVDEVVFIESEHSERRRIKAERLERIAISAMKQSLKASFPVI 144 >3K9D-A nrPDB Length = 464 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 37/107 (34%), Gaps = 13/107 (12%) Query: 4 KFFVGGNWKCN-GTAEEVKKIVNTLNEAQVPSQDVVEVV----VSPPYVFLPLVKSTLRS 58 KF + N N + + + L VP+ V + V +P + L Sbjct: 289 KFILRPNGSMNPAIVGKSVQHIANLAGLTVPADARVLIAEETKVGAK---IPYSREKLAP 345 Query: 59 DFFVAAQNCWVKKGGAFTGEVSAEMLVNLDIPWVILGHSERRAILNE 105 W + E+S ++L + ++ HSE + I+ E Sbjct: 346 ILAFYTAETWQEAC-----ELSMDILYHEGAGHTLIIHSEDKEIIRE 387 >5LZY-jj nrPDB Length = 710 Score = 28.3 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 7/81 (8%) Query: 77 GEVSAEMLVNLDIPWVILGHSERRAILN-ESSEFVGDKVAYALAQGLKVIACVGETLEER 135 G V A + +LG+ +R + E K ++A A L ET EER Sbjct: 293 GHVDAGKSTLMGHMLYLLGNINKRTMHKYEQESKKAGKASFAYAWVLD------ETGEER 346 Query: 136 EAGSTMDVVAAQTKAIADRVT 156 E G TMDV + + +T Sbjct: 347 ERGVTMDVGMTKFETTTKVIT 367 >5FGE-J nrPDB Length = 198 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 18/42 (42%) Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGG 223 Q V +R+ LAK++ + ++ GG N EL Sbjct: 77 PQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 >3WXR-K nrPDB Length = 238 Score = 28.3 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 18/42 (42%) Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGG 223 Q V +R+ LAK++ + ++ GG N EL Sbjct: 77 PQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQ 118 >4AF1-A nrPDB Length = 416 Score = 27.9 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 11/22 (50%), Positives = 15/22 (68%), Gaps = 1/22 (4%) Query: 223 GQADVDGFLVGGAS-LKPEFID 243 + ++DG LVGG S K EF+D Sbjct: 218 KRHEIDGILVGGPSPTKDEFLD 239 >3MBJ-A nrPDB Length = 291 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 21/45 (46%), Gaps = 3/45 (6%) Query: 148 TKAIADRVTNWSNVVIAYEPVWAIGTGKVASPAQAQEVHDELRKW 192 T + + W + + + AI TG + SP Q Q V D ++ + Sbjct: 61 TDEMPKIIAEWKKLEVQF---DAIYTGYLGSPRQIQIVSDFIKDF 102 >3H9B-A nrPDB Length = 560 Score = 27.5 bits (60), Expect = 5.1, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 15/37 (40%) Query: 128 VGETLEEREAGSTMDVVAAQTKAIADRVTNWSNVVIA 164 +GE E RE G + + A V + V+A Sbjct: 441 IGEAWESREFGKAVREIMALADLANRYVDEQAPWVVA 477 >6GKI-A nrPDB Length = 198 Score = 27.5 bits (60), Expect = 5.4, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 14/28 (50%) Query: 175 KVASPAQAQEVHDELRKWLAKNVSADVA 202 K A+PAQ + R++L + +A Sbjct: 62 KSATPAQREAYFAAFREYLKQAYGQALA 89 >6HIV-CJ nrPDB Length = 817 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 20/43 (46%), Gaps = 5/43 (11%) Query: 182 AQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGG-----NCK 219 A++V L+ + V + A R++ GG+V+ NC Sbjct: 261 AEDVCMFLKDVGRQIVEEKLVAVRRLLQGGAVDPELLAAFNCA 303 >4NNP-A nrPDB Length = 291 Score = 27.1 bits (59), Expect = 7.5, Method: Composition-based stats. Identities = 7/25 (28%), Positives = 14/25 (56%) Query: 168 VWAIGTGKVASPAQAQEVHDELRKW 192 +W I T K +P Q ++ + ++K Sbjct: 205 IWEINTEKQGTPEQMRQAIEFVKKH 229 >2VOU-A nrPDB Length = 397 Score = 26.8 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 20/48 (41%), Gaps = 8/48 (16%) Query: 181 QAQEVHDELRKWLAKNVSADVAATTRIIYGGSVNGGNCKELGGQADVD 228 Q Q+ H L K + K S R+ +GGS GN G VD Sbjct: 350 QLQQGHAYLNK-VKKMAS-------RLQHGGSFEPGNPAFAFGLPKVD 389 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.153 0.479 Lambda K H 0.267 0.0470 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,311,517 Number of Sequences: 36641 Number of extensions: 490059 Number of successful extensions: 1634 Number of sequences better than 10.0: 71 Number of HSP's better than 10.0 without gapping: 115 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 1311 Number of HSP's gapped (non-prelim): 141 length of query: 254 length of database: 10,336,785 effective HSP length: 95 effective length of query: 159 effective length of database: 6,855,890 effective search space: 1090086510 effective search space used: 1090086510 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.8 bits)