BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P48052 (419 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1AYE-A nrPDB 834 0.0 1DTD-A nrPDB 623 e-179 5OM9-A nrPDB 549 e-157 2BOA-A nrPDB 545 e-156 1PCA-A nrPDB 533 e-152 4BD9-A nrPDB 461 e-130 3KGQ-A nrPDB 442 e-124 4UEE-A nrPDB 442 e-124 1KWM-A nrPDB 334 5e-92 3GLJ-A nrPDB 329 2e-90 1NSA-A nrPDB 322 1e-88 1ZLI-A nrPDB 311 5e-85 4UIB-A nrPDB 290 1e-78 3OSL-A nrPDB 276 1e-74 3D68-A nrPDB 271 3e-73 3D4U-A nrPDB 259 1e-69 3LMS-A nrPDB 256 2e-68 1CPB-B nrPDB 246 2e-65 5MRV-A nrPDB 240 9e-64 1JQG-A nrPDB 191 5e-49 2C1C-A nrPDB 180 9e-46 1O6X-A nrPDB 160 1e-39 3V7Z-A nrPDB 130 2e-30 1PYT-A nrPDB 107 1e-23 1CPB-A nrPDB 55 5e-08 1QMU-A nrPDB 50 3e-06 2NSM-A nrPDB 49 3e-06 3MN8-A nrPDB 48 9e-06 4B6Z-A nrPDB 44 2e-04 3K2K-A nrPDB 43 2e-04 1UWY-A nrPDB 43 2e-04 3L2N-A nrPDB 42 4e-04 4A39-A nrPDB 37 0.015 4R3Z-C nrPDB 31 0.79 3QGV-A nrPDB 31 1.2 2VK9-A nrPDB 30 1.8 3A22-A nrPDB 30 2.5 3FMC-A nrPDB 29 3.4 4OZ5-A nrPDB 29 4.7 5A5X-A nrPDB 28 5.9 5WQ7-A nrPDB 28 9.0 3IEH-A nrPDB 28 9.9 >1AYE-A nrPDB Length = 401 Score = 834 bits (2154), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/401 (99%), Positives = 400/401 (99%) Query: 19 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK 78 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK Sbjct: 1 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK 60 Query: 79 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA 138 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA Sbjct: 61 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA 120 Query: 139 EHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVS 198 EHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVS Sbjct: 121 EHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVS 180 Query: 199 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWD 258 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWD Sbjct: 181 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWD 240 Query: 259 AGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGY 318 AGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFI LHSYSQLLMFPYGY Sbjct: 241 AGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFIILHSYSQLLMFPYGY 300 Query: 319 KCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFA 378 KCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFA Sbjct: 301 KCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFA 360 Query: 379 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY Sbjct: 361 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 401 >1DTD-A nrPDB Length = 303 Score = 623 bits (1607), Expect = e-179, Method: Compositional matrix adjust. Identities = 299/303 (98%), Positives = 299/303 (98%), Gaps = 1/303 (0%) Query: 118 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAG 177 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAG Sbjct: 1 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAG 60 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR Sbjct: 61 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 120 Query: 238 KTRSKVS-GSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 KTRSKVS GSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH Sbjct: 121 KTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 180 Query: 297 GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSV 356 GKVKAFI LHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSL LHGTKYKVGPICSV Sbjct: 181 GKVKAFIILHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLSRLHGTKYKVGPICSV 240 Query: 357 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 416 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD Sbjct: 241 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 300 Query: 417 HPY 419 HPY Sbjct: 301 HPY 303 >5OM9-A nrPDB Length = 419 Score = 549 bits (1415), Expect = e-157, Method: Compositional matrix adjust. Identities = 258/406 (63%), Positives = 314/406 (77%), Gaps = 2/406 (0%) Query: 16 IYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQ 75 ++ E FVG QVL I ++E Q++ + +LE EHLQLDFW+ P PG VRVPF ++Q Sbjct: 14 VFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQ 73 Query: 76 AVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGAYHTLEEISQEMD 134 AVK+FLES GI+Y MIEDVQ LLD+E E+M R R RS + FN+ YHTLEEI +D Sbjct: 74 AVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLD 133 Query: 135 NLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHAREWVTQATALWTA 193 LVAE+P LVSK+ IG+++E RP+ VLKFSTGG K PAIW+D GIH+REWVTQA+ +W A Sbjct: 134 LLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFA 193 Query: 194 NKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDP 253 KI DYG+D + T+ILD LDIFL VTNPDG+ F+ + NRMWRKTRS +GSLC+GVDP Sbjct: 194 KKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDP 253 Query: 254 NRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLM 313 NRNWDAGFG GASSNPCS++YHG ANSEVEVKSIVDF+K HG +KAFI++HSYSQLLM Sbjct: 254 NRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLM 313 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 +PYGYK + D DEL ++++ A +L SL+GTK+ G I IYQASG +IDW+Y GI Sbjct: 314 YPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGI 373 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 KYSF FELRDTGRYGFLLPA QI+PTA+ETWL L IMEH +HPY Sbjct: 374 KYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419 >2BOA-A nrPDB Length = 404 Score = 545 bits (1405), Expect = e-156, Method: Compositional matrix adjust. Identities = 256/403 (63%), Positives = 314/403 (77%), Gaps = 3/403 (0%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKV 79 E F GDQVL I N ++I L QL +L+L+FWKSP++ V VP V++QA K Sbjct: 2 EKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKS 61 Query: 80 FLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERS-GNFNFGAYHTLEEISQEMDNLVA 138 FL SQG+ Y++ IED+Q LLD E++EM N +ERS NFN+GAYH+LE I EMDN+ A Sbjct: 62 FLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAA 121 Query: 139 EHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGIHAREWVTQATALWTANKI 196 + P L +V IG SFENRPM VLKFSTG +PA+WL+AGIH+REW++QATA+WTA KI Sbjct: 122 DFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKI 181 Query: 197 VSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRN 256 VSDY +DP+ITSIL+ +DIFLLPV NPDGYV++QT+NR+WRKTRS+ GS C+G DPNRN Sbjct: 182 VSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRN 241 Query: 257 WDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPY 316 W+A F G GAS NPCS+ YHGP ANSEVEVKS+VDFI+ HG K FI LHSYSQLLM+PY Sbjct: 242 WNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPY 301 Query: 317 GYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYS 376 GY K D +EL +VA+ AA++L S+ GT+Y+VGP C+ +Y ASG SIDW+YD GIK++ Sbjct: 302 GYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFA 361 Query: 377 FAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 F FELRDTG YGFLLPA QI+PTAEETWLGLK IMEHVRD+ Y Sbjct: 362 FTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY 404 >1PCA-A nrPDB Length = 403 Score = 533 bits (1373), Expect = e-152, Method: Compositional matrix adjust. Identities = 249/397 (62%), Positives = 313/397 (78%), Gaps = 2/397 (0%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKV 79 E FVG QVL I +E Q++ + +LE EHLQLDFW+ P PG VRVPF ++QAVKV Sbjct: 3 EDFVGHQVLRISVDDEAQVQKVKELEDLEHLQLDFWRGPARPGFPIDVRVPFPSIQAVKV 62 Query: 80 FLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERS-GNFNFGAYHTLEEISQEMDNLVA 138 FLE+ GI Y+IMIEDVQ+LLD+E E+M ++ R R+ FN+ YHTLEEI MD LVA Sbjct: 63 FLEAHGIRYTIMIEDVQLLLDEEQEQMFASQGRARTTSTFNYATYHTLEEIYDFMDILVA 122 Query: 139 EHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLDAGIHAREWVTQATALWTANKIV 197 EHP LVSK+ IG S+E RP+ VLKFSTGG ++PAIW+D+GIH+REW+TQA+ +W A KI Sbjct: 123 EHPALVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDSGIHSREWITQASGVWFAKKIT 182 Query: 198 SDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNW 257 +YG++ S T+ILD++DIFL VTNP+G+ F+ + NR+WRKTRSK SGSLCVG D NRNW Sbjct: 183 ENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWRKTRSKASGSLCVGSDSNRNW 242 Query: 258 DAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYG 317 DAGFGG GASS+PC+++YHG NSEVEVKSI DF+K++G +KAFI++HSYSQLL++PYG Sbjct: 243 DAGFGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNGNIKAFISIHSYSQLLLYPYG 302 Query: 318 YKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSF 377 YK D EL+++A+ A +L+SL+GT YK G I +VIYQASGG IDW+Y+ GIKYSF Sbjct: 303 YKTQSPADKSELNQIAKSAVAALKSLYGTSYKYGSIITVIYQASGGVIDWTYNQGIKYSF 362 Query: 378 AFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414 +FELRDTGR GFLLPA QI+PTA+ETWL L IMEH Sbjct: 363 SFELRDTGRRGFLLPASQIIPTAQETWLALLTIMEHT 399 >4BD9-A nrPDB Length = 310 Score = 461 bits (1187), Expect = e-130, Method: Compositional matrix adjust. Identities = 210/307 (68%), Positives = 252/307 (82%), Gaps = 2/307 (0%) Query: 115 SGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAI 172 S NFN+GAYH+LE I EMDN+ A+ P L +V IG SFENRPM VLKFSTG +PA+ Sbjct: 4 SNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAV 63 Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232 WL+AGIH+REW++QATA+WTA KIVSDY +DP+ITSIL+ +DIFLLPV NPDGYV++QT+ Sbjct: 64 WLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQ 123 Query: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292 NR+WRKTRS+ GS C+G DPNRNW+A F G GAS NPCS+ YHGP ANSEVEVKS+VDF Sbjct: 124 NRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDF 183 Query: 293 IKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGP 352 I+ HG K FI LHSYSQLLM+PYGY K D +EL +VA+ AA++L S+ GT+Y+VGP Sbjct: 184 IQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGP 243 Query: 353 ICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIME 412 C+ +Y ASG SIDW+YD GIK++F FELRDTG YGFLLPA QI+PTAEETWLGLK IME Sbjct: 244 TCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIME 303 Query: 413 HVRDHPY 419 HVRD+ Y Sbjct: 304 HVRDNLY 310 >3KGQ-A nrPDB Length = 309 Score = 442 bits (1136), Expect = e-124, Method: Compositional matrix adjust. Identities = 205/308 (66%), Positives = 249/308 (80%), Gaps = 2/308 (0%) Query: 114 RSGN-FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPA 171 RS N FN+ YHTL+EI MD LVAEHP LVSK+ IG S+E RP+ VLKFSTGG ++PA Sbjct: 2 RSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPA 61 Query: 172 IWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQT 231 IW+D GIH+REW+TQAT +W A K DYG+DPS T+ILD++DIFL VTNPDG+ F+ + Sbjct: 62 IWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHS 121 Query: 232 KNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVD 291 +NR+WRKTRS S SLCVGVD NRNWDAGFG GASS+PCS++YHG ANSEVEVKSIVD Sbjct: 122 QNRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVD 181 Query: 292 FIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351 F+K HG KAF+++HSYSQLL++PYGY + D EL++VA+ A ++L+SL+GT YK G Sbjct: 182 FVKDHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYG 241 Query: 352 PICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIM 411 I + IYQASGGSIDWSY+ GIKYSF FELRDTGRYGFLLPA QI+PTA+ETWLG+ IM Sbjct: 242 SIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIM 301 Query: 412 EHVRDHPY 419 EH ++ Y Sbjct: 302 EHTLNNLY 309 >4UEE-A nrPDB Length = 309 Score = 442 bits (1136), Expect = e-124, Method: Compositional matrix adjust. Identities = 203/304 (66%), Positives = 243/304 (79%), Gaps = 1/304 (0%) Query: 117 NFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLD 175 FN+ YHTLEEI +D LVAE+P LVSK+ IG+++E RP+ VLKFSTGG K PAIW+D Sbjct: 6 TFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWID 65 Query: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235 GIH+REWVTQA+ +W A KI DYG+D + T+ILD LDIFL VTNPDG+ F+ + NRM Sbjct: 66 TGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRM 125 Query: 236 WRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295 WRKTRS +GSLC+GVDPNRNWDAGFG GASSNPCS++YHG ANSEVEVKSIVDF+K Sbjct: 126 WRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKD 185 Query: 296 HGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICS 355 HG +KAFI++HSYSQLLM+PYGYK + D DEL ++++ A +L SL+GTK+ G I Sbjct: 186 HGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIK 245 Query: 356 VIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVR 415 IYQASG +IDW+Y GIKYSF FELRDTGRYGFLLPA QI+PTA+ETWL L IMEH Sbjct: 246 AIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 305 Query: 416 DHPY 419 +HPY Sbjct: 306 NHPY 309 >1KWM-A nrPDB Length = 402 Score = 334 bits (856), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 167/406 (41%), Positives = 254/406 (62%), Gaps = 14/406 (3%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWK----SPTTPGETAHVRVPFVNVQ 75 E F G++V + +E I + +L + Q+DFWK + P T RV + Sbjct: 5 EHFEGEKVFRVNVEDENHINIIRELAST--TQIDFWKPDSVTQIKPHSTVDFRVKAEDTV 62 Query: 76 AVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDN 135 V+ L+ + Y ++I +++ +++ + F+ R +G+ ++ Y+ E I Sbjct: 63 TVENVLKQNELQYKVLISNLRNVVEAQ-----FDSRVRATGH-SYEKYNKWETIEAWTQQ 116 Query: 136 LVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLDAGIHAREWVTQATALWTAN 194 + E+P L+S+ IG++FE R + +LK G +KPAI++D G HAREW++ A W Sbjct: 117 VATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVR 176 Query: 195 KIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPN 254 + V YG++ +T +L+ LD ++LPV N DGY+++ TK+R WRKTRS +GS C+G DPN Sbjct: 177 EAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPN 236 Query: 255 RNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313 RN+DAG+ GAS NPC ++Y GP+A SE E K++ DFI++ +KA++T+HSYSQ+++ Sbjct: 237 RNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMI 296 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 +PY Y ++ EL+ +A+ + L SLHGTKY GP + IY A+GGS DW+YD GI Sbjct: 297 YPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGI 356 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 +YSF FELRDTGRYGFLLP QI T EET+L +K + +V +H Y Sbjct: 357 RYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY 402 >3GLJ-A nrPDB Length = 401 Score = 329 bits (843), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 167/404 (41%), Positives = 252/404 (62%), Gaps = 14/404 (3%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWK----SPTTPGETAHVRVPFVNVQ 75 E F G++V + +E I L +L + Q+DFWK + P T RV ++ Sbjct: 5 EHFEGEKVFRVNVEDENDISLLHELASTR--QIDFWKPDSVTQIKPHSTVDFRVKAEDIL 62 Query: 76 AVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDN 135 AV+ FLE + Y ++I +++ +L E F+ R +G+ ++ Y+ E I Sbjct: 63 AVEDFLEQNELQYEVLINNLRSVL-----EAQFDSRVRTTGH-SYEKYNNWETIEAWTKQ 116 Query: 136 LVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLDAGIHAREWVTQATALWTAN 194 + +E+P L+S+ IG++F + +LK G +KPAI++D G HAREW++ A W Sbjct: 117 VTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVR 176 Query: 195 KIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPN 254 + V YG + +T L+ LD ++LPV N DGY+++ TKNRMWRKTRS +G+ C+G DPN Sbjct: 177 EAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPN 236 Query: 255 RNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313 RN+DAG+ GAS++PC ++Y G +A SE E K++ DFI+++ +KA++T+HSYSQ+++ Sbjct: 237 RNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMIL 296 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 +PY Y ++ EL+ +A+ A + L +L+GTKY GP + IY A+GGS DW+YD GI Sbjct: 297 YPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGI 356 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417 KYSF FELRD GRYGF+LP QI T EET L +K + +V H Sbjct: 357 KYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGH 400 >1NSA-A nrPDB Length = 395 Score = 322 bits (826), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 161/402 (40%), Positives = 250/402 (62%), Gaps = 14/402 (3%) Query: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWK----SPTTPGETAHVRVPFVNVQAV 77 F G++V + +E I L +L + Q+DFWK + P T RV ++ AV Sbjct: 1 FEGEKVFRVNVEDENDISELHELASTR--QIDFWKPDSVTQIKPHSTVDFRVKAEDILAV 58 Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137 + FLE + Y ++I +++ +L+ + + + R+ ++ Y+ E I + + Sbjct: 59 EDFLEQNELQYEVLINNLRSVLEAQFDSV------SRTTGHSYEKYNNWETIEAWTEQVT 112 Query: 138 AEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIWLDAGIHAREWVTQATALWTANKI 196 +++P L+S+ IG++F+ + +LK G +KPAI++D G HAREW++QA W Sbjct: 113 SKNPDLISRSAIGTTFDGDNIYLLKVGKPGSNKPAIFMDCGFHAREWISQAFCQWFVRDA 172 Query: 197 VSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRN 256 V YG + +T LD LD ++LPV N DGY+++ TKNRMWRKTRS +GS C G DPNRN Sbjct: 173 VRTYGYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGSSCTGTDPNRN 232 Query: 257 WDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLMFP 315 ++AG+ GAS NPC+++Y G +A SE E K++ DFI+++ +KA++T+HSYSQ++++P Sbjct: 233 FNAGWCTVGASVNPCNETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYP 292 Query: 316 YGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKY 375 Y Y ++ EL+ +A+ A + L SL+GT Y GP + IY A+GGS DW+Y+ GIKY Sbjct: 293 YSYDYKLPENDAELNSLAKGAVKELASLYGTSYSYGPGSTTIYPAAGGSDDWAYNQGIKY 352 Query: 376 SFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417 SF FELRD GR+GF+LP QI T +ET L +K + + +H Sbjct: 353 SFTFELRDKGRFGFVLPESQIQATCQETMLAVKYVTNYTLEH 394 >1ZLI-A nrPDB Length = 309 Score = 311 bits (796), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 145/308 (47%), Positives = 208/308 (67%), Gaps = 2/308 (0%) Query: 114 RSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAI 172 R+ ++ Y+ E I + E+P L+S+ IG++FE R + +LK G +KPAI Sbjct: 2 RATGHSYEKYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI 61 Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232 ++D G HAREW++ A W + V YG++ +T +L+ LD ++LPV N DGY+++ TK Sbjct: 62 FMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTK 121 Query: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292 +R WRKTRS +GS C+G DPNRN+DAG+ GAS NPC ++Y GP+A SE E K++ DF Sbjct: 122 SRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADF 181 Query: 293 IKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351 I++ +KA++T+HSYSQ++++PY Y ++ EL+ +A+ + L SLHGTKY G Sbjct: 182 IRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYG 241 Query: 352 PICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIM 411 P + IY A+GGS DW+YD GI+YSF FELRDTGRYGFLLP QI T EET+L +K + Sbjct: 242 PGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVA 301 Query: 412 EHVRDHPY 419 +V +H Y Sbjct: 302 SYVLEHLY 309 >4UIB-A nrPDB Length = 307 Score = 290 bits (741), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 137/303 (45%), Positives = 201/303 (66%), Gaps = 2/303 (0%) Query: 119 NFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLDAG 177 ++ Y+ E I + +E+P L+S+ IG++F + +LK G +KPAI++D G Sbjct: 5 SYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCG 64 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 IHAREW++ A W + V YG + +T L+ LD ++LPV N DGY+++ TKNRMWR Sbjct: 65 IHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWR 124 Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH- 296 KTRS +G+ C+G DPNRN+DAG+ GAS++PC ++Y G +A SE E K++ DFI+++ Sbjct: 125 KTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNL 184 Query: 297 GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSV 356 +KA++++HSYSQ +++PY Y ++ EL+ +A+ A + L +L+GTKY GP + Sbjct: 185 SSIKAYLSIHSYSQHIVYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATT 244 Query: 357 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 416 +Y A GG DW+YD GIKYSF FELRD GRYGF+LP QI T EET L +K + +V Sbjct: 245 LYLAPGGGDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLG 304 Query: 417 HPY 419 H Y Sbjct: 305 HLY 307 >3OSL-A nrPDB Length = 401 Score = 276 bits (707), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 154/402 (38%), Positives = 229/402 (56%), Gaps = 14/402 (3%) Query: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAV 77 F QVL +P Q++ L + + L W+ G H V +V V Sbjct: 1 FQRGQVLSALPRTSRQVQILQNVTTTYKIVL--WQPVAAEYIVKGYEVHFFVNASDVSNV 58 Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137 K L + I + +++E+V+ L+ ++ + R S + YH+L EI ++ + Sbjct: 59 KAHLNASRIPFRVLVENVEDLIRQQTSNDTISPRASSS---YYEQYHSLNEIYSWIEVMT 115 Query: 138 AEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGIHAREWVTQATALWTANK 195 +P +V K++IGSS+E P+ VLK S K A+W+D GIHAREW++ A LW Sbjct: 116 ERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAMWIDCGIHAREWISPAFCLWFVGS 175 Query: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255 + YGK+ T++L +D +++PV N DGY ++ K+RMWRK RS + CVG D NR Sbjct: 176 VTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMWRKNRSLHEKNACVGTDLNR 235 Query: 256 NWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK-VKAFITLHSYSQLLM 313 N+ + + G GASS+ CS+ Y G SE EVK++ DF++ + K +KA+I++HSYSQ ++ Sbjct: 236 NFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRRNIKHIKAYISMHSYSQKIV 295 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLH-GTKYKVGPICSVIYQASGGSIDWSYDYG 372 FPY Y ++ D +ELS VA++A ++ ++H +Y G +Y A GGS DW YD G Sbjct: 296 FPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYTHGSGSESLYLAPGGSDDWIYDLG 355 Query: 373 IKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414 IKYSF FELRD G+YGFLLP I PT E + + I HV Sbjct: 356 IKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAKIASHV 397 >3D68-A nrPDB Length = 424 Score = 271 bits (694), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 156/398 (39%), Positives = 224/398 (56%), Gaps = 14/398 (3%) Query: 26 QVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAVKVFL 81 QVL +P Q++ L L + L W+ T + H V +V VK L Sbjct: 28 QVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNVKAHL 85 Query: 82 ESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHP 141 GI S+++ DV+ L+ ++ + R S + YH+L EI ++ + HP Sbjct: 86 NVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFITERHP 142 Query: 142 GLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGIHAREWVTQATALWTANKIVSD 199 +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW I Sbjct: 143 DMLTKIHIGSSFEKYPLYVLKVSGKEQTAKNAIWIDCGIHAREWISPAFCLWFIGHITQF 202 Query: 200 YGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDA 259 YG T++L +D +++PV N DGY +S KNRMWRK RS + + C+G D NRN+ + Sbjct: 203 YGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFAS 262 Query: 260 G-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLMFPYG 317 + GASS+ CS++Y G SE EVK++ F++ + ++KA+I++HSYSQ ++FPY Sbjct: 263 KHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYS 322 Query: 318 YKCTKLDDFDELSEVAQKAAQSLRSL-HGTKYKVGPICSVIYQASGGSIDWSYDYGIKYS 376 Y +K D +ELS VA +A +++ + +Y G +Y A GG DW YD GIKYS Sbjct: 323 YTRSKSKDHEELSLVASEAVRAIEKISKNIRYTYGQGSETLYLAPGGGDDWIYDLGIKYS 382 Query: 377 FAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414 F ELRDTG YGFLLP R I PT E + + I HV Sbjct: 383 FTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 420 >3D4U-A nrPDB Length = 309 Score = 259 bits (663), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 132/300 (44%), Positives = 189/300 (63%), Gaps = 5/300 (1%) Query: 120 FGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAG 177 + YH+L EI ++ + +P +V K++IGSS+E P+ VLK S K A+W+D G Sbjct: 6 YEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAMWIDCG 65 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 IHAREW++ A LW + YGK+ T++L +D +++PV N DGY ++ K+RMWR Sbjct: 66 IHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMWR 125 Query: 238 KTRSKVSGSLCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 K RS + CVG D NRN+ + + G GASS+ CS+ Y G SE EVK++ DF++ + Sbjct: 126 KNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRRN 185 Query: 297 GK-VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLH-GTKYKVGPIC 354 K +KA+I++HSYSQ ++FPY Y ++ D +ELS VA++A ++ ++H +Y G Sbjct: 186 IKHIKAYISMHSYSQKIVFPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYTHGSGS 245 Query: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414 +Y A GGS DW YD GIKYSF FELRD G+YGFLLP I PT E + + I HV Sbjct: 246 ESLYLAPGGSDDWIYDLGIKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAKIASHV 305 >3LMS-A nrPDB Length = 309 Score = 256 bits (653), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 133/300 (44%), Positives = 187/300 (62%), Gaps = 5/300 (1%) Query: 120 FGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAG 177 + YH+L EI ++ + HP +++K++IGSSFE P+ VLK S K AIW+D G Sbjct: 6 YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCG 65 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 IHAREW++ A LW I YG T++L +D +++PV N DGY +S KNRMWR Sbjct: 66 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 125 Query: 238 KTRSKVSGSLCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 K RS + + C+G D NRN+ + + GASS+ CS++Y G SE EVK++ F++ + Sbjct: 126 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 185 Query: 297 -GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSL-RSLHGTKYKVGPIC 354 ++KA+I++HSYSQ ++FPY Y +K D +ELS VA +A +++ ++ T+Y G Sbjct: 186 INQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGS 245 Query: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414 +Y A GG DW YD GIKYSF ELRDTG YGFLLP R I PT E + + I HV Sbjct: 246 ETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 305 >1CPB-B nrPDB Length = 217 Score = 246 bits (627), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 115/213 (53%), Positives = 152/213 (71%), Gaps = 1/213 (0%) Query: 206 ITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPG 265 +T LD LD ++LPV N DGY+++ T NRMWRKTRS +GS C G D NRN+DAG+ G Sbjct: 4 MTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWCSIG 63 Query: 266 ASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLD 324 AS+NPCS++Y G +A SE E K++ DFI++H +KA++T+HSYSQ++++PY Y Sbjct: 64 ASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYSYDYKLPK 123 Query: 325 DFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDT 384 + EL+ +A+ A + L SLHGT Y GP + IY ASGGS DW+YD GIKYSF FELRD Sbjct: 124 NNVELNTLAKGAVKKLASLHGTTYSYGPGATTIYPASGGSDDWAYDQGIKYSFTFELRDK 183 Query: 385 GRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417 GRYGF+LP QI PT EET L +K + +V +H Sbjct: 184 GRYGFVLPESQIQPTCEETMLAIKYVTSYVLEH 216 >5MRV-A nrPDB Length = 355 Score = 240 bits (612), Expect = 9e-64, Method: Compositional matrix adjust. Identities = 117/300 (39%), Positives = 184/300 (61%), Gaps = 3/300 (1%) Query: 118 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLD 175 +++ YH + EI + M + ++ +V++ +G ++E P+ LK S +G K IW+D Sbjct: 51 YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPIYYLKISQPSGNPKKIIWMD 110 Query: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235 GIHAREW+ A W +I+ ++ + I +L LD ++LPV N DGY+++ T +R+ Sbjct: 111 CGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 170 Query: 236 WRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295 WRK+RS + C G D NRN++A + GAS N ++ G SE E K++ FI+S Sbjct: 171 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 230 Query: 296 H-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC 354 + F+T+HSY QL++ PYGY K + E+ +V QKAA +L++ +GT Y+VG Sbjct: 231 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 290 Query: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414 ++Y +SG S DW+ D GI +S+ FELRD+G YGF+LP QI PT EET + ++++ V Sbjct: 291 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDV 350 >1JQG-A nrPDB Length = 433 Score = 191 bits (485), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 131/420 (31%), Positives = 218/420 (51%), Gaps = 27/420 (6%) Query: 7 LFFGALF--GHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGET 64 LF LF G + E + G V ++ ++ +Q+K L + + L LD W S PG Sbjct: 4 LFIFCLFVAGVLAKHEIYDGHAVYQVDVASMDQVK--LVHDFENDLMLDVW-SDAVPGRP 60 Query: 65 AHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERS--GNFNFGA 122 V VP + + FL+ G+ Y + +E+V+ L+ E++ + + S +F Sbjct: 61 GKVLVPKFKREIFENFLKQSGVQYKLEVENVKEQLELEDQLLAAAAAKSNSTRSRLSFDK 120 Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST----GGDKPAIWLDAGI 178 H+ EE+ + L E P +V+ V G SFE R + L+ ST KP + + + + Sbjct: 121 IHSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSIKYLRISTTNFQDASKPVVMMQSLL 180 Query: 179 HAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRK 238 H REWVT L+ +K+V D + + +++ +D +LPV NPDGYV + +R WRK Sbjct: 181 HCREWVTLPATLYAIHKLVIDVTE----SDLINNIDWIILPVANPDGYVHTFGGDRYWRK 236 Query: 239 TRSK--VSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 R+ ++G+LC+GVD NRN+ + G +SS+ CSD++HG SA SE E I D I H Sbjct: 237 NRATGYMAGNLCMGVDLNRNFGMNW-GTASSSSVCSDTFHGRSAFSEPESSVIRDIIAEH 295 Query: 297 -GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLH---GTKYKVGP 352 ++ ++ +HS+ ++++ YG + +L + + AQ++ + Y VG Sbjct: 296 RNRMALYLDIHSFGSMILYGYGNGVLPSNAL-QLHLIGVQMAQAIDRVKWSSNKDYIVGN 354 Query: 353 ICSVIYQASGGSIDWSYDYGIKYSFAFEL---RDTGRY-GFLLPARQILPTAEETWLGLK 408 I V+Y ASGG+ D++ +S+ +EL R++ + GFL+ I ETW G+K Sbjct: 355 IFHVLYAASGGASDYAMQAAAPFSYTYELPAYRNSVWFDGFLVDPDFIEQAGFETWEGIK 414 >2C1C-A nrPDB Length = 312 Score = 180 bits (457), Expect = 9e-46, Method: Compositional matrix adjust. Identities = 106/302 (35%), Positives = 165/302 (54%), Gaps = 18/302 (5%) Query: 120 FGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG----DKPAIWLD 175 + Y LE I + +D + ++P + + VN SFE RP+ +K ST +KP I++D Sbjct: 3 YDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFID 62 Query: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235 GIHAREW++ + W +K+V D ++ +L+ D LLPV NPDGY ++ T R Sbjct: 63 GGIHAREWISPPSVTWAIHKLVEDVTEN----DLLEKFDWILLPVVNPDGYKYTFTNERF 118 Query: 236 WRKTRSKVSGSL---CVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292 WRKTRS + L C G D NRN+D + G S++PCSD Y G SA SEVE + + D Sbjct: 119 WRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDI 178 Query: 293 IKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRS---LHGTKY 348 + H ++ ++T+HS+ ++++P+G+ + + L V A ++S + Y Sbjct: 179 LHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPY 238 Query: 349 KVGPICSVI-YQASGGSIDWSYDYGIKYSFAFELR--DTGRYGFLLPARQILPTAEETWL 405 VG VI Y +G S D+++ G+ S+ +EL +G GF LP + I ETW Sbjct: 239 TVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWE 298 Query: 406 GL 407 G+ Sbjct: 299 GI 300 >1O6X-A nrPDB Length = 81 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 78/79 (98%), Positives = 78/79 (98%) Query: 18 CLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV 77 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV Sbjct: 3 SLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV 62 Query: 78 KVFLESQGIAYSIMIEDVQ 96 KVFLESQGIAYSIMIEDVQ Sbjct: 63 KVFLESQGIAYSIMIEDVQ 81 >3V7Z-A nrPDB Length = 326 Score = 130 bits (326), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 97/308 (31%), Positives = 153/308 (49%), Gaps = 27/308 (8%) Query: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS----TGGDKPAIWLDAG 177 YH E+ +++ + + +P +V K +IG S+E R + +K S T ++P + A Sbjct: 8 GYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVLYTAL 67 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDG--YVFSQTKNRM 235 HARE +T AL+T + +Y D IT++++ +I+++ NPDG Y S + Sbjct: 68 HHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSGSYKS 127 Query: 236 WRKTRSKVSGSLCVGVDPNRNWDAGF-GGPGASSNPCSDSYHGPSANSEVEVKSIVDFIK 294 WRK R SGS VG D NRN+ + G+S +P S++Y G SA S E ++ DFI Sbjct: 128 WRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMRDFIN 187 Query: 295 SH---GK--VKAFITLHSYSQLLMFPYGYKCTKL------DDFDELSEVAQKAAQSLRSL 343 S GK +K IT H+YS+L+++PYGY T + DDF+ +A AQ Sbjct: 188 SRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQ----- 242 Query: 344 HGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEET 403 T S +Y G DW+Y ++F FE+ T P +++ ET Sbjct: 243 --TNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVI--GRET 298 Query: 404 WLGLKAIM 411 +A++ Sbjct: 299 SRNKEAVL 306 >1PYT-A nrPDB Length = 94 Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 52/93 (55%), Positives = 67/93 (72%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKV 79 E FVG QVL I ++E +++ + +LE EHLQLDFW+ P PG VRVPF ++QAVKV Sbjct: 2 EDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPGSPIDVRVPFPSLQAVKV 61 Query: 80 FLESQGIAYSIMIEDVQVLLDKENEEMLFNRRR 112 FLE+ GI Y IMIEDVQ LLD+E E+M ++ R Sbjct: 62 FLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSR 94 >1CPB-A nrPDB Length = 82 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 25/74 (33%), Positives = 44/74 (59%), Gaps = 1/74 (1%) Query: 119 NFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIWLDAG 177 ++ Y+ E I + + +E+P L+S+ IG++F + +LK G +KPA+++D G Sbjct: 5 SYEKYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNKPAVFMDCG 64 Query: 178 IHAREWVTQATALW 191 HAREW++ A W Sbjct: 65 FHAREWISPAFCQW 78 >1QMU-A nrPDB Length = 380 Score = 49.7 bits (117), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 56/269 (20%), Positives = 107/269 (39%), Gaps = 42/269 (15%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTG-----GDKPAIWLDAG 177 +H ++ + E+P + ++G S E R + V++ S +P Sbjct: 10 HHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEPEFKYIGN 69 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 +H E V + L + ++G DP +T ++ + I ++P NPDGY SQ +R Sbjct: 70 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQEGDR--- 126 Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG 297 VG + + N+D P D + + + E +++ ++K++ Sbjct: 127 --------GGTVGRNNSNNYDLNRNFP--------DQFFQVTDPPQPETLAVMSWLKTYP 170 Query: 298 KVKAFITLHSYSQLLMFPY-------GYKCTKLDD--FDELSEVAQKAAQSL------RS 342 V + LH S ++ +P+ DD F +L+ K + + + Sbjct: 171 FVLS-ANLHGGSLVVNYPFDDDEQGIAIYSKSPDDAVFQQLALSYSKENKKMYQGSPCKD 229 Query: 343 LHGTKYKVGPICSVI--YQASGGSIDWSY 369 L+ T+Y I + Y GG DW+Y Sbjct: 230 LYPTEYFPHGITNGAQWYNVPGGMQDWNY 258 >2NSM-A nrPDB Length = 439 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 47/209 (22%), Positives = 91/209 (43%), Gaps = 22/209 (10%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177 +H +++ + + + E PG+ +IG S E R + VL+FS +P + Sbjct: 6 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 65 Query: 178 IHAREWVTQATALWTANKIVSDY-GKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 236 +H E + + L + + ++ ++ I ++ I +LP NPDGY + + Sbjct: 66 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP-- 123 Query: 237 RKTRSKVSGSLCVGVDPNRN---------WDAGFGGPGASSNPCSDSYHGPSANSEVEVK 287 K V + GVD NRN ++ +GGP P D++ + E E + Sbjct: 124 NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHL-PLPDNW---KSQVEPETR 179 Query: 288 SIVDFIKSHGKVKAFITLHSYSQLLMFPY 316 +++ ++ S V + LH + + +PY Sbjct: 180 AVIRWMHSFNFVLS-ANLHGGAVVANYPY 207 >3MN8-A nrPDB Length = 435 Score = 47.8 bits (112), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 5/116 (4%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 177 Y + E++ L +P +G S E R + L+ S P + A Sbjct: 40 YASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIAN 99 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKN 233 +H E V + ++ A ++ ++ + + ++++ DI+L+P NPDGY SQ N Sbjct: 100 MHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGN 155 >4B6Z-A nrPDB Length = 405 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/137 (26%), Positives = 53/137 (38%), Gaps = 31/137 (22%) Query: 144 VSKVNIGSSFENRPMNVLKFST----GGDKPAIWLDAGIHAREWVTQATALWTANKIV-- 197 S V +G + E RPM++L T G K +W I AR+ ++ A W +V Sbjct: 153 ASVVELGRTVEGRPMSLLTLGTPETDGAPKKKVW----IIARQHPGESMAEWFVEGLVKR 208 Query: 198 ----SDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDP 253 D+ DP + D + ++P NPDG V + G + Sbjct: 209 LAGWGDWAGDPVARKLYDRVTFHIVPNMNPDGSVHGNLRTN-------------AAGANL 255 Query: 254 NRNWDAGFGGPGASSNP 270 NR W A P A +P Sbjct: 256 NREWMA----PDAERSP 268 >3K2K-A nrPDB Length = 403 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 38/144 (26%), Positives = 59/144 (40%), Gaps = 23/144 (15%) Query: 127 EEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST----GGDKPAIWLDAGIHARE 182 EE E V + P S V +G + E RPM+++ T G K +W I AR+ Sbjct: 135 EERHSEFLGAVQQMP-QASVVELGRTVEGRPMSLVVLGTPDEAGAAKKKVW----IIARQ 189 Query: 183 WVTQATALWTANKIV------SDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK---- 232 ++ A W +V D+ DP + D +++P NPDG V + Sbjct: 190 HPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHATFYIVPNMNPDGSVHGNLRTNAA 249 Query: 233 ----NRMWRKTRSKVSGSLCVGVD 252 NR W + ++ S + V D Sbjct: 250 GANLNREWMEPDAERSPEVLVVRD 273 >1UWY-A nrPDB Length = 426 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 36/153 (23%), Positives = 63/153 (41%), Gaps = 10/153 (6%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 177 YH E + + + + + +IG S + R + VL + P A Sbjct: 5 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 64 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + + + Sbjct: 65 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 124 Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNP 270 R + D NRN+ F S P Sbjct: 125 IGRENYN-----QYDLNRNFPDAFEYNNVSRQP 152 >3L2N-A nrPDB Length = 395 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 37/141 (26%), Positives = 63/141 (44%), Gaps = 23/141 (16%) Query: 122 AYHTLEEISQEMD--NLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPA---IWLDA 176 AY T + +D + V HP LVS ++G + + R M ++K G D P+ IW+ A Sbjct: 126 AYFTPYSYERHLDLISAVQLHP-LVSTEHLGLTLDGRDMTLVK--VGDDDPSKKSIWITA 182 Query: 177 GIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 236 H E + + N+++ + P+ ++LD + +++P NPDG V + Sbjct: 183 RQHPGETMAEWLVEGLLNQLLDN--DCPTSKALLDKANFYIVPNMNPDGSVRGHLRTN-- 238 Query: 237 RKTRSKVSGSLCVGVDPNRNW 257 VG + NR W Sbjct: 239 -----------AVGANLNREW 248 >4A39-A nrPDB Length = 388 Score = 37.0 bits (84), Expect = 0.015, Method: Compositional matrix adjust. Identities = 36/171 (21%), Positives = 64/171 (37%), Gaps = 39/171 (22%) Query: 144 VSKVNIGSSFENRPMNVLKFSTGGDKP-AIWLDAGIHAREWVTQATALWTANKIVSDYGK 202 V ++ +G+S + R + +L+ D +W+ A H E + + W ++ + Sbjct: 144 VERLAVGTSVQGRDIELLRVRRHPDSHLKLWVIAQQHPGEHMAE----WFMEGLIERLQR 199 Query: 203 --DPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAG 260 D + +L+ D++L+P NPDG + G D NR W Sbjct: 200 PDDTEMQRLLEKADLYLVPNMNPDGAFHGNLRTN-------------AAGQDLNRAWLE- 245 Query: 261 FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQL 311 PSA EV + +K HG V F+ +H ++ Sbjct: 246 -----------------PSAERSPEVWFVQQEMKRHG-VDLFLDIHGDEEI 278 >4R3Z-C nrPDB Length = 799 Score = 31.2 bits (69), Expect = 0.79, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 323 LDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELR 382 L F L QKA ++L++ ++ + Q G +ID + + Y A LR Sbjct: 31 LSLFTSLGLSEQKARETLKN-SALSAQLREAATQAQQTLGSTIDKATGI-LLYGLASRLR 88 Query: 383 DTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418 DT R FL+ I T L A +E+VR HP Sbjct: 89 DTRRLSFLV--SYIASKKIHTEPQLSAALEYVRSHP 122 >3QGV-A nrPDB Length = 435 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 10/103 (9%) Query: 89 SIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVN 148 +I D + L+K+ + L +G Y+ +E+ + N + PGL++ +N Sbjct: 311 TIFYRDYEEWLNKDKLKNLIWIHENLAGGSTDIVYYDNDELIF-VRNGYGDKPGLITYIN 369 Query: 149 IGSSFENRPMNVLKFS-------TGGDKPAIWLDAGIHAREWV 184 +GSS R + V KF+ TG W+D +++ WV Sbjct: 370 LGSSKAGRWVYVPKFAGACIHEYTG--NLGGWVDKYVYSSGWV 410 >2VK9-A nrPDB Length = 551 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 9/69 (13%) Query: 242 KVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHG--------PSANSEV-EVKSIVDF 292 ++ G L G P N F GP S+ D+YH S N E+ E + + F Sbjct: 455 QIIGYLSSGFKPEVNSTVFFSGPNIYSSATCDTYHFIKNTFDMLSSQNQEIFEASNNLYF 514 Query: 293 IKSHGKVKA 301 K+H + K+ Sbjct: 515 SKTHDEFKS 523 >3A22-A nrPDB Length = 614 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 19/45 (42%) Query: 182 EWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGY 226 W LW + + YG PS+TS+L D L P GY Sbjct: 189 NWAAGQAPLWRTSTDIIYYGNQPSMTSLLSNFDQTLHPTAQHTGY 233 >3FMC-A nrPDB Length = 368 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 12/82 (14%) Query: 146 KVNIGSSFENRPMN--VLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKD 203 +V +G +P++ V +F G P++++ A +H E V ++ K++ Y Sbjct: 8 EVRVGELAAGQPLSLPVYRFKGKGAGPSVYIQANVHGAE-VQGNAVIYQLMKLLEHY--- 63 Query: 204 PSITSILDALDIFLLPVTNPDG 225 +L DI L+P+ NP G Sbjct: 64 ----ELLG--DISLVPLANPLG 79 >4OZ5-A nrPDB Length = 155 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 7/77 (9%) Query: 93 EDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSS 152 E++ ++ +EN ++ E SG+ F A H E I Q + +HPG NI + Sbjct: 23 ENILLMQGQENAILI----HETSGDTVFQAPHAYEVIDQVGE---IKHPGFAVLNNIAVT 75 Query: 153 FENRPMNVLKFSTGGDK 169 E RP+ KF K Sbjct: 76 QEGRPLFENKFKNRAGK 92 >5A5X-A nrPDB Length = 453 Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 7/59 (11%) Query: 63 ETAHVRVPFVNVQAVKVFLESQGIAYSI-------MIEDVQVLLDKENEEMLFNRRRER 114 E A +V F NV+ F E++G+A+++ ++ +V LD+ +E L R ++R Sbjct: 169 ELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDDSLMNEVNAFLDQAKKEGLLQRLKDR 227 >5WQ7-A nrPDB Length = 627 Score = 27.7 bits (60), Expect = 9.0, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 24/44 (54%) Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIF 216 W + + A+++ ++ A + V+DY K+ ITS A D+F Sbjct: 346 WANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMF 389 >3IEH-A nrPDB Length = 276 Score = 27.7 bits (60), Expect = 9.9, Method: Compositional matrix adjust. Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 23/98 (23%) Query: 170 PAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFS 229 P++ + AG H E + W +S+ D + + +++ LLP+ NP G+ Sbjct: 67 PSLLISAGFHGEE----SAGPWGLLHFLSEASAD-----LFERVNLSLLPLVNPTGFSRG 117 Query: 230 QTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGAS 267 N+ G +PNR + G P A+ Sbjct: 118 HRFNKY--------------GENPNRGFVFENGKPKAN 141 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1AYE-A nrPDB 627 e-180 5OM9-A nrPDB 595 e-170 1PCA-A nrPDB 582 e-167 2BOA-A nrPDB 572 e-163 3GLJ-A nrPDB 555 e-158 1KWM-A nrPDB 553 e-158 1NSA-A nrPDB 544 e-155 3OSL-A nrPDB 504 e-143 3D68-A nrPDB 503 e-143 1DTD-A nrPDB 481 e-136 1ZLI-A nrPDB 464 e-131 3KGQ-A nrPDB 459 e-129 4BD9-A nrPDB 459 e-129 4UEE-A nrPDB 458 e-129 4UIB-A nrPDB 458 e-129 1JQG-A nrPDB 426 e-120 3LMS-A nrPDB 416 e-116 3D4U-A nrPDB 414 e-116 5MRV-A nrPDB 403 e-113 1CPB-B nrPDB 343 7e-95 2C1C-A nrPDB 328 2e-90 3V7Z-A nrPDB 278 2e-75 1QMU-A nrPDB 227 7e-60 2NSM-A nrPDB 192 3e-49 1UWY-A nrPDB 191 4e-49 3MN8-A nrPDB 172 2e-43 1PYT-A nrPDB 137 7e-33 3K2K-A nrPDB 126 2e-29 4B6Z-A nrPDB 122 2e-28 1O6X-A nrPDB 120 1e-27 3L2N-A nrPDB 117 6e-27 1CPB-A nrPDB 114 1e-25 Sequences not found previously or not previously below threshold: 1PBA-A nrPDB 94 8e-20 4A39-A nrPDB 88 5e-18 3B2Y-A nrPDB 51 1e-06 2QVP-A nrPDB 50 3e-06 3IEH-A nrPDB 46 3e-05 5HXD-A nrPDB 43 2e-04 5Y10-C nrPDB 37 0.011 4OKO-A nrPDB 36 0.027 3FMC-A nrPDB 34 0.15 4WXU-A nrPDB 32 0.51 4U2L-A nrPDB 31 1.1 4OZ5-A nrPDB 30 2.4 2G9D-A nrPDB 30 2.8 3AK8-A nrPDB 29 4.1 4UOO-A nrPDB 28 7.9 3C0Q-A nrPDB 28 8.6 4LO5-B nrPDB 28 9.0 >1AYE-A nrPDB Length = 401 Score = 627 bits (1617), Expect = e-180, Method: Composition-based stats. Identities = 400/401 (99%), Positives = 400/401 (99%) Query: 19 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK 78 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK Sbjct: 1 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK 60 Query: 79 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA 138 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA Sbjct: 61 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA 120 Query: 139 EHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVS 198 EHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVS Sbjct: 121 EHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVS 180 Query: 199 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWD 258 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWD Sbjct: 181 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWD 240 Query: 259 AGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGY 318 AGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFI LHSYSQLLMFPYGY Sbjct: 241 AGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFIILHSYSQLLMFPYGY 300 Query: 319 KCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFA 378 KCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFA Sbjct: 301 KCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFA 360 Query: 379 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY Sbjct: 361 FELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 401 >5OM9-A nrPDB Length = 419 Score = 595 bits (1533), Expect = e-170, Method: Composition-based stats. Identities = 258/406 (63%), Positives = 314/406 (77%), Gaps = 2/406 (0%) Query: 16 IYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQ 75 ++ E FVG QVL I ++E Q++ + +LE EHLQLDFW+ P PG VRVPF ++Q Sbjct: 14 VFGKEDFVGHQVLRISVADEAQVQKVKELEDLEHLQLDFWRGPAHPGSPIDVRVPFPSIQ 73 Query: 76 AVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGAYHTLEEISQEMD 134 AVK+FLES GI+Y MIEDVQ LLD+E E+M R R RS + FN+ YHTLEEI +D Sbjct: 74 AVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDFLD 133 Query: 135 NLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-PAIWLDAGIHAREWVTQATALWTA 193 LVAE+P LVSK+ IG+++E RP+ VLKFSTGG K PAIW+D GIH+REWVTQA+ +W A Sbjct: 134 LLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRPAIWIDTGIHSREWVTQASGVWFA 193 Query: 194 NKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDP 253 KI DYG+D + T+ILD LDIFL VTNPDG+ F+ + NRMWRKTRS +GSLC+GVDP Sbjct: 194 KKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIGVDP 253 Query: 254 NRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLM 313 NRNWDAGFG GASSNPCS++YHG ANSEVEVKSIVDF+K HG +KAFI++HSYSQLLM Sbjct: 254 NRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGNIKAFISIHSYSQLLM 313 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 +PYGYK + D DEL ++++ A +L SL+GTK+ G I IYQASG +IDW+Y GI Sbjct: 314 YPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNYGSIIKAIYQASGSTIDWTYSQGI 373 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 KYSF FELRDTGRYGFLLPA QI+PTA+ETWL L IMEH +HPY Sbjct: 374 KYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNHPY 419 >1PCA-A nrPDB Length = 403 Score = 582 bits (1501), Expect = e-167, Method: Composition-based stats. Identities = 249/402 (61%), Positives = 315/402 (78%), Gaps = 2/402 (0%) Query: 18 CLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV 77 E FVG QVL I +E Q++ + +LE EHLQLDFW+ P PG VRVPF ++QAV Sbjct: 1 KKEDFVGHQVLRISVDDEAQVQKVKELEDLEHLQLDFWRGPARPGFPIDVRVPFPSIQAV 60 Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSG-NFNFGAYHTLEEISQEMDNL 136 KVFLE+ GI Y+IMIEDVQ+LLD+E E+M ++ R R+ FN+ YHTLEEI MD L Sbjct: 61 KVFLEAHGIRYTIMIEDVQLLLDEEQEQMFASQGRARTTSTFNYATYHTLEEIYDFMDIL 120 Query: 137 VAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKPAIWLDAGIHAREWVTQATALWTANK 195 VAEHP LVSK+ IG S+E RP+ VLKFSTGG ++PAIW+D+GIH+REW+TQA+ +W A K Sbjct: 121 VAEHPALVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDSGIHSREWITQASGVWFAKK 180 Query: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255 I +YG++ S T+ILD++DIFL VTNP+G+ F+ + NR+WRKTRSK SGSLCVG D NR Sbjct: 181 ITENYGQNSSFTAILDSMDIFLEIVTNPNGFAFTHSDNRLWRKTRSKASGSLCVGSDSNR 240 Query: 256 NWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFP 315 NWDAGFGG GASS+PC+++YHG NSEVEVKSI DF+K++G +KAFI++HSYSQLL++P Sbjct: 241 NWDAGFGGAGASSSPCAETYHGKYPNSEVEVKSITDFVKNNGNIKAFISIHSYSQLLLYP 300 Query: 316 YGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKY 375 YGYK D EL+++A+ A +L+SL+GT YK G I +VIYQASGG IDW+Y+ GIKY Sbjct: 301 YGYKTQSPADKSELNQIAKSAVAALKSLYGTSYKYGSIITVIYQASGGVIDWTYNQGIKY 360 Query: 376 SFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417 SF+FELRDTGR GFLLPA QI+PTA+ETWL L IMEH ++ Sbjct: 361 SFSFELRDTGRRGFLLPASQIIPTAQETWLALLTIMEHTLNN 402 >2BOA-A nrPDB Length = 404 Score = 572 bits (1473), Expect = e-163, Method: Composition-based stats. Identities = 256/403 (63%), Positives = 314/403 (77%), Gaps = 3/403 (0%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKV 79 E F GDQVL I N ++I L QL +L+L+FWKSP++ V VP V++QA K Sbjct: 2 EKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQAFKS 61 Query: 80 FLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGN-FNFGAYHTLEEISQEMDNLVA 138 FL SQG+ Y++ IED+Q LLD E++EM N +ERS N FN+GAYH+LE I EMDN+ A Sbjct: 62 FLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNIAA 121 Query: 139 EHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGIHAREWVTQATALWTANKI 196 + P L +V IG SFENRPM VLKFSTG +PA+WL+AGIH+REW++QATA+WTA KI Sbjct: 122 DFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTARKI 181 Query: 197 VSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRN 256 VSDY +DP+ITSIL+ +DIFLLPV NPDGYV++QT+NR+WRKTRS+ GS C+G DPNRN Sbjct: 182 VSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRN 241 Query: 257 WDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPY 316 W+A F G GAS NPCS+ YHGP ANSEVEVKS+VDFI+ HG K FI LHSYSQLLM+PY Sbjct: 242 WNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPY 301 Query: 317 GYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYS 376 GY K D +EL +VA+ AA++L S+ GT+Y+VGP C+ +Y ASG SIDW+YD GIK++ Sbjct: 302 GYSVKKAPDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGIKFA 361 Query: 377 FAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 F FELRDTG YGFLLPA QI+PTAEETWLGLK IMEHVRD+ Y Sbjct: 362 FTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNLY 404 >3GLJ-A nrPDB Length = 401 Score = 555 bits (1430), Expect = e-158, Method: Composition-based stats. Identities = 165/405 (40%), Positives = 250/405 (61%), Gaps = 14/405 (3%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKS----PTTPGETAHVRVPFVNVQ 75 E F G++V + +E I L +L + Q+DFWK P T RV ++ Sbjct: 5 EHFEGEKVFRVNVEDENDISLLHELASTR--QIDFWKPDSVTQIKPHSTVDFRVKAEDIL 62 Query: 76 AVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDN 135 AV+ FLE + Y ++I +++ +L+ + + R R+ ++ Y+ E I Sbjct: 63 AVEDFLEQNELQYEVLINNLRSVLEAQFD------SRVRTTGHSYEKYNNWETIEAWTKQ 116 Query: 136 LVAEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIWLDAGIHAREWVTQATALWTAN 194 + +E+P L+S+ IG++F + +LK G +KPAI++D G HAREW++ A W Sbjct: 117 VTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVR 176 Query: 195 KIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPN 254 + V YG + +T L+ LD ++LPV N DGY+++ TKNRMWRKTRS +G+ C+G DPN Sbjct: 177 EAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPN 236 Query: 255 RNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313 RN+DAG+ GAS++PC ++Y G +A SE E K++ DFI+++ +KA++T+HSYSQ+++ Sbjct: 237 RNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMIL 296 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 +PY Y ++ EL+ +A+ A + L +L+GTKY GP + IY A+GGS DW+YD GI Sbjct: 297 YPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGI 356 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418 KYSF FELRD GRYGF+LP QI T EET L +K + +V H Sbjct: 357 KYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL 401 >1KWM-A nrPDB Length = 402 Score = 553 bits (1424), Expect = e-158, Method: Composition-based stats. Identities = 166/406 (40%), Positives = 251/406 (61%), Gaps = 14/406 (3%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKS----PTTPGETAHVRVPFVNVQ 75 E F G++V + +E I + +L + Q+DFWK P T RV + Sbjct: 5 EHFEGEKVFRVNVEDENHINIIRELAST--TQIDFWKPDSVTQIKPHSTVDFRVKAEDTV 62 Query: 76 AVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDN 135 V+ L+ + Y ++I +++ +++ + + R R+ ++ Y+ E I Sbjct: 63 TVENVLKQNELQYKVLISNLRNVVEAQFD------SRVRATGHSYEKYNKWETIEAWTQQ 116 Query: 136 LVAEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIWLDAGIHAREWVTQATALWTAN 194 + E+P L+S+ IG++FE R + +LK G +KPAI++D G HAREW++ A W Sbjct: 117 VATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREWISPAFCQWFVR 176 Query: 195 KIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPN 254 + V YG++ +T +L+ LD ++LPV N DGY+++ TK+R WRKTRS +GS C+G DPN Sbjct: 177 EAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTHTGSSCIGTDPN 236 Query: 255 RNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313 RN+DAG+ GAS NPC ++Y GP+A SE E K++ DFI++ +KA++T+HSYSQ+++ Sbjct: 237 RNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMI 296 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 +PY Y ++ EL+ +A+ + L SLHGTKY GP + IY A+GGS DW+YD GI Sbjct: 297 YPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGI 356 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHPY 419 +YSF FELRDTGRYGFLLP QI T EET+L +K + +V +H Y Sbjct: 357 RYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY 402 >1NSA-A nrPDB Length = 395 Score = 544 bits (1401), Expect = e-155, Method: Composition-based stats. Identities = 161/403 (39%), Positives = 248/403 (61%), Gaps = 14/403 (3%) Query: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKS----PTTPGETAHVRVPFVNVQAV 77 F G++V + +E I L +L + Q+DFWK P T RV ++ AV Sbjct: 1 FEGEKVFRVNVEDENDISELHELASTR--QIDFWKPDSVTQIKPHSTVDFRVKAEDILAV 58 Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137 + FLE + Y ++I +++ +L+ + + R+ ++ Y+ E I + + Sbjct: 59 EDFLEQNELQYEVLINNLRSVLEAQFD------SVSRTTGHSYEKYNNWETIEAWTEQVT 112 Query: 138 AEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIWLDAGIHAREWVTQATALWTANKI 196 +++P L+S+ IG++F+ + +LK G +KPAI++D G HAREW++QA W Sbjct: 113 SKNPDLISRSAIGTTFDGDNIYLLKVGKPGSNKPAIFMDCGFHAREWISQAFCQWFVRDA 172 Query: 197 VSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRN 256 V YG + +T LD LD ++LPV N DGY+++ TKNRMWRKTRS +GS C G DPNRN Sbjct: 173 VRTYGYEAHMTEFLDNLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGSSCTGTDPNRN 232 Query: 257 WDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLMFP 315 ++AG+ GAS NPC+++Y G +A SE E K++ DFI+++ +KA++T+HSYSQ++++P Sbjct: 233 FNAGWCTVGASVNPCNETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYP 292 Query: 316 YGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKY 375 Y Y ++ EL+ +A+ A + L SL+GT Y GP + IY A+GGS DW+Y+ GIKY Sbjct: 293 YSYDYKLPENDAELNSLAKGAVKELASLYGTSYSYGPGSTTIYPAAGGSDDWAYNQGIKY 352 Query: 376 SFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418 SF FELRD GR+GF+LP QI T +ET L +K + + +H Sbjct: 353 SFTFELRDKGRFGFVLPESQIQATCQETMLAVKYVTNYTLEHL 395 >3OSL-A nrPDB Length = 401 Score = 504 bits (1298), Expect = e-143, Method: Composition-based stats. Identities = 154/405 (38%), Positives = 230/405 (56%), Gaps = 14/405 (3%) Query: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAV 77 F QVL +P Q++ L + + L W+ G H V +V V Sbjct: 1 FQRGQVLSALPRTSRQVQILQNVTTTYKIVL--WQPVAAEYIVKGYEVHFFVNASDVSNV 58 Query: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137 K L + I + +++E+V+ L+ ++ + R S + YH+L EI ++ + Sbjct: 59 KAHLNASRIPFRVLVENVEDLIRQQTSNDTISPRASSS---YYEQYHSLNEIYSWIEVMT 115 Query: 138 AEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGIHAREWVTQATALWTANK 195 +P +V K++IGSS+E P+ VLK S K A+W+D GIHAREW++ A LW Sbjct: 116 ERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAMWIDCGIHAREWISPAFCLWFVGS 175 Query: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255 + YGK+ T++L +D +++PV N DGY ++ K+RMWRK RS + CVG D NR Sbjct: 176 VTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKKDRMWRKNRSLHEKNACVGTDLNR 235 Query: 256 NWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGK-VKAFITLHSYSQLLM 313 N+ + + G GASS+ CS+ Y G SE EVK++ DF++ + K +KA+I++HSYSQ ++ Sbjct: 236 NFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVADFLRRNIKHIKAYISMHSYSQKIV 295 Query: 314 FPYGYKCTKLDDFDELSEVAQKAAQSLRSLH-GTKYKVGPICSVIYQASGGSIDWSYDYG 372 FPY Y ++ D +ELS VA++A ++ ++H +Y G +Y A GGS DW YD G Sbjct: 296 FPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYTHGSGSESLYLAPGGSDDWIYDLG 355 Query: 373 IKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417 IKYSF FELRD G+YGFLLP I PT E + + I HV + Sbjct: 356 IKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAKIASHVVKN 400 >3D68-A nrPDB Length = 424 Score = 503 bits (1294), Expect = e-143, Method: Composition-based stats. Identities = 156/404 (38%), Positives = 225/404 (55%), Gaps = 14/404 (3%) Query: 23 VGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPT----TPGETAHVRVPFVNVQAVK 78 QVL +P Q++ L L + L W+ T + H V +V VK Sbjct: 25 QSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNVK 82 Query: 79 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVA 138 L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ + Sbjct: 83 AHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFITE 139 Query: 139 EHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAIWLDAGIHAREWVTQATALWTANKI 196 HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW I Sbjct: 140 RHPDMLTKIHIGSSFEKYPLYVLKVSGKEQTAKNAIWIDCGIHAREWISPAFCLWFIGHI 199 Query: 197 VSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRN 256 YG T++L +D +++PV N DGY +S KNRMWRK RS + + C+G D NRN Sbjct: 200 TQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRN 259 Query: 257 WDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLMF 314 + + + GASS+ CS++Y G SE EVK++ F++ + ++KA+I++HSYSQ ++F Sbjct: 260 FASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVF 319 Query: 315 PYGYKCTKLDDFDELSEVAQKAAQSLRSL-HGTKYKVGPICSVIYQASGGSIDWSYDYGI 373 PY Y +K D +ELS VA +A +++ + +Y G +Y A GG DW YD GI Sbjct: 320 PYSYTRSKSKDHEELSLVASEAVRAIEKISKNIRYTYGQGSETLYLAPGGGDDWIYDLGI 379 Query: 374 KYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDH 417 KYSF ELRDTG YGFLLP R I PT E + + I HV + Sbjct: 380 KYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 423 >1DTD-A nrPDB Length = 303 Score = 481 bits (1239), Expect = e-136, Method: Composition-based stats. Identities = 299/303 (98%), Positives = 299/303 (98%), Gaps = 1/303 (0%) Query: 118 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAG 177 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAG Sbjct: 1 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDKPAIWLDAG 60 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR Sbjct: 61 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 120 Query: 238 KTRSKVS-GSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 KTRSKVS GSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH Sbjct: 121 KTRSKVSAGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 180 Query: 297 GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSV 356 GKVKAFI LHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSL LHGTKYKVGPICSV Sbjct: 181 GKVKAFIILHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLSRLHGTKYKVGPICSV 240 Query: 357 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 416 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD Sbjct: 241 IYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRD 300 Query: 417 HPY 419 HPY Sbjct: 301 HPY 303 >1ZLI-A nrPDB Length = 309 Score = 464 bits (1193), Expect = e-131, Method: Composition-based stats. Identities = 145/308 (47%), Positives = 208/308 (67%), Gaps = 2/308 (0%) Query: 114 RSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAI 172 R+ ++ Y+ E I + E+P L+S+ IG++FE R + +LK G +KPAI Sbjct: 2 RATGHSYEKYNNWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAI 61 Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232 ++D G HAREW++ A W + V YG++ +T +L+ LD ++LPV N DGY+++ TK Sbjct: 62 FMDCGFHAREWISPAFCQWFVREAVRTYGREIQVTELLNKLDFYVLPVLNIDGYIYTWTK 121 Query: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292 +R WRKTRS +GS C+G DPNRN+DAG+ GAS NPC ++Y GP+A SE E K++ DF Sbjct: 122 SRFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADF 181 Query: 293 IKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351 I++ +KA++T+HSYSQ++++PY Y ++ EL+ +A+ + L SLHGTKY G Sbjct: 182 IRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYG 241 Query: 352 PICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIM 411 P + IY A+GGS DW+YD GI+YSF FELRDTGRYGFLLP QI T EET+L +K + Sbjct: 242 PGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVA 301 Query: 412 EHVRDHPY 419 +V +H Y Sbjct: 302 SYVLEHLY 309 >3KGQ-A nrPDB Length = 309 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 202/309 (65%), Positives = 247/309 (79%), Gaps = 1/309 (0%) Query: 112 RERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGG-DKP 170 + FN+ YHTL+EI MD LVAEHP LVSK+ IG S+E RP+ VLKFSTGG ++P Sbjct: 1 ARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRP 60 Query: 171 AIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQ 230 AIW+D GIH+REW+TQAT +W A K DYG+DPS T+ILD++DIFL VTNPDG+ F+ Sbjct: 61 AIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTH 120 Query: 231 TKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIV 290 ++NR+WRKTRS S SLCVGVD NRNWDAGFG GASS+PCS++YHG ANSEVEVKSIV Sbjct: 121 SQNRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIV 180 Query: 291 DFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKV 350 DF+K HG KAF+++HSYSQLL++PYGY + D EL++VA+ A ++L+SL+GT YK Sbjct: 181 DFVKDHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKY 240 Query: 351 GPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAI 410 G I + IYQASGGSIDWSY+ GIKYSF FELRDTGRYGFLLPA QI+PTA+ETWLG+ I Sbjct: 241 GSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTI 300 Query: 411 MEHVRDHPY 419 MEH ++ Y Sbjct: 301 MEHTLNNLY 309 >4BD9-A nrPDB Length = 310 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 210/309 (67%), Positives = 252/309 (81%), Gaps = 2/309 (0%) Query: 113 ERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KP 170 S NFN+GAYH+LE I EMDN+ A+ P L +V IG SFENRPM VLKFSTG +P Sbjct: 2 RSSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRP 61 Query: 171 AIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQ 230 A+WL+AGIH+REW++QATA+WTA KIVSDY +DP+ITSIL+ +DIFLLPV NPDGYV++Q Sbjct: 62 AVWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQ 121 Query: 231 TKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIV 290 T+NR+WRKTRS+ GS C+G DPNRNW+A F G GAS NPCS+ YHGP ANSEVEVKS+V Sbjct: 122 TQNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVV 181 Query: 291 DFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKV 350 DFI+ HG K FI LHSYSQLLM+PYGY K D +EL +VA+ AA++L S+ GT+Y+V Sbjct: 182 DFIQKHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQV 241 Query: 351 GPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAI 410 GP C+ +Y ASG SIDW+YD GIK++F FELRDTG YGFLLPA QI+PTAEETWLGLK I Sbjct: 242 GPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTI 301 Query: 411 MEHVRDHPY 419 MEHVRD+ Y Sbjct: 302 MEHVRDNLY 310 >4UEE-A nrPDB Length = 309 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 203/309 (65%), Positives = 244/309 (78%), Gaps = 1/309 (0%) Query: 112 RERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-P 170 + FN+ YHTLEEI +D LVAE+P LVSK+ IG+++E RP+ VLKFSTGG K P Sbjct: 1 ARSTDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGSKRP 60 Query: 171 AIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQ 230 AIW+D GIH+REWVTQA+ +W A KI DYG+D + T+ILD LDIFL VTNPDG+ F+ Sbjct: 61 AIWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTH 120 Query: 231 TKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIV 290 + NRMWRKTRS +GSLC+GVDPNRNWDAGFG GASSNPCS++YHG ANSEVEVKSIV Sbjct: 121 STNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIV 180 Query: 291 DFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKV 350 DF+K HG +KAFI++HSYSQLLM+PYGYK + D DEL ++++ A +L SL+GTK+ Sbjct: 181 DFVKDHGNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNY 240 Query: 351 GPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAI 410 G I IYQASG +IDW+Y GIKYSF FELRDTGRYGFLLPA QI+PTA+ETWL L I Sbjct: 241 GSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTI 300 Query: 411 MEHVRDHPY 419 MEH +HPY Sbjct: 301 MEHTLNHPY 309 >4UIB-A nrPDB Length = 307 Score = 458 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 137/307 (44%), Positives = 202/307 (65%), Gaps = 2/307 (0%) Query: 115 SGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIW 173 + ++ Y+ E I + +E+P L+S+ IG++F + +LK G +KPAI+ Sbjct: 1 TTGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIF 60 Query: 174 LDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKN 233 +D GIHAREW++ A W + V YG + +T L+ LD ++LPV N DGY+++ TKN Sbjct: 61 MDCGIHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKN 120 Query: 234 RMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFI 293 RMWRKTRS +G+ C+G DPNRN+DAG+ GAS++PC ++Y G +A SE E K++ DFI Sbjct: 121 RMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFI 180 Query: 294 KSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGP 352 +++ +KA++++HSYSQ +++PY Y ++ EL+ +A+ A + L +L+GTKY GP Sbjct: 181 RNNLSSIKAYLSIHSYSQHIVYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGP 240 Query: 353 ICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIME 412 + +Y A GG DW+YD GIKYSF FELRD GRYGF+LP QI T EET L +K + Sbjct: 241 GATTLYLAPGGGDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTN 300 Query: 413 HVRDHPY 419 +V H Y Sbjct: 301 YVLGHLY 307 >1JQG-A nrPDB Length = 433 Score = 426 bits (1096), Expect = e-120, Method: Composition-based stats. Identities = 130/420 (30%), Positives = 218/420 (51%), Gaps = 27/420 (6%) Query: 7 LFFGALF--GHIYCLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGET 64 LF LF G + E + G V ++ ++ +Q+K + + + L LD W S PG Sbjct: 4 LFIFCLFVAGVLAKHEIYDGHAVYQVDVASMDQVKLVH--DFENDLMLDVW-SDAVPGRP 60 Query: 65 AHVRVPFVNVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSG--NFNFGA 122 V VP + + FL+ G+ Y + +E+V+ L+ E++ + + S +F Sbjct: 61 GKVLVPKFKREIFENFLKQSGVQYKLEVENVKEQLELEDQLLAAAAAKSNSTRSRLSFDK 120 Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST----GGDKPAIWLDAGI 178 H+ EE+ + L E P +V+ V G SFE R + L+ ST KP + + + + Sbjct: 121 IHSYEEVDAYLQELAKEFPNVVTVVEGGKSFEGRSIKYLRISTTNFQDASKPVVMMQSLL 180 Query: 179 HAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRK 238 H REWVT L+ +K+V D + + +++ +D +LPV NPDGYV + +R WRK Sbjct: 181 HCREWVTLPATLYAIHKLVIDVTE----SDLINNIDWIILPVANPDGYVHTFGGDRYWRK 236 Query: 239 TRSK--VSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 R+ ++G+LC+GVD NRN+ + G +SS+ CSD++HG SA SE E I D I H Sbjct: 237 NRATGYMAGNLCMGVDLNRNFGMNW-GTASSSSVCSDTFHGRSAFSEPESSVIRDIIAEH 295 Query: 297 -GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLH---GTKYKVGP 352 ++ ++ +HS+ ++++ YG + +L + + AQ++ + Y VG Sbjct: 296 RNRMALYLDIHSFGSMILYGYGNGV-LPSNALQLHLIGVQMAQAIDRVKWSSNKDYIVGN 354 Query: 353 ICSVIYQASGGSIDWSYDYGIKYSFAFEL---RDTGRY-GFLLPARQILPTAEETWLGLK 408 I V+Y ASGG+ D++ +S+ +EL R++ + GFL+ I ETW G+K Sbjct: 355 IFHVLYAASGGASDYAMQAAAPFSYTYELPAYRNSVWFDGFLVDPDFIEQAGFETWEGIK 414 >3LMS-A nrPDB Length = 309 Score = 416 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 133/308 (43%), Positives = 189/308 (61%), Gaps = 5/308 (1%) Query: 115 SGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAI 172 + + YH+L EI ++ + HP +++K++IGSSFE P+ VLK S K AI Sbjct: 1 ASASYYEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI 60 Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232 W+D GIHAREW++ A LW I YG T++L +D +++PV N DGY +S K Sbjct: 61 WIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKK 120 Query: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVD 291 NRMWRK RS + + C+G D NRN+ + + GASS+ CS++Y G SE EVK++ Sbjct: 121 NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVAS 180 Query: 292 FIKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSL-RSLHGTKYK 349 F++ + ++KA+I++HSYSQ ++FPY Y +K D +ELS VA +A +++ ++ T+Y Sbjct: 181 FLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYT 240 Query: 350 VGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKA 409 G +Y A GG DW YD GIKYSF ELRDTG YGFLLP R I PT E + + Sbjct: 241 HGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSK 300 Query: 410 IMEHVRDH 417 I HV + Sbjct: 301 IAWHVIRN 308 >3D4U-A nrPDB Length = 309 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 132/308 (42%), Positives = 192/308 (62%), Gaps = 5/308 (1%) Query: 115 SGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD--KPAI 172 + + + YH+L EI ++ + +P +V K++IGSS+E P+ VLK S K A+ Sbjct: 1 ASSSYYEQYHSLNEIYSWIEVMTERYPDMVEKIHIGSSYEKYPLYVLKVSKKEQRAKNAM 60 Query: 173 WLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTK 232 W+D GIHAREW++ A LW + YGK+ T++L +D +++PV N DGY ++ K Sbjct: 61 WIDCGIHAREWISPAFCLWFVGSVTYYYGKEKMHTNLLKHMDFYIMPVVNVDGYDYTWKK 120 Query: 233 NRMWRKTRSKVSGSLCVGVDPNRNWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVD 291 +RMWRK RS + CVG D NRN+ + + G GASS+ CS+ Y G SE EVK++ D Sbjct: 121 DRMWRKNRSLHEKNACVGTDLNRNFASKHWCGEGASSSSCSEIYCGTYPESEPEVKAVAD 180 Query: 292 FIKSHGK-VKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLH-GTKYK 349 F++ + K +KA+I++HSYSQ ++FPY Y ++ D +ELS VA++A ++ ++H +Y Sbjct: 181 FLRRNIKHIKAYISMHSYSQKIVFPYSYSRSRSKDHEELSLVAREAVFAMENIHRNIRYT 240 Query: 350 VGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKA 409 G +Y A GGS DW YD GIKYSF FELRD G+YGFLLP I PT E + + Sbjct: 241 HGSGSESLYLAPGGSDDWIYDLGIKYSFTFELRDKGKYGFLLPESYIRPTCSEALVAVAK 300 Query: 410 IMEHVRDH 417 I HV + Sbjct: 301 IASHVVKN 308 >5MRV-A nrPDB Length = 355 Score = 403 bits (1035), Expect = e-113, Method: Composition-based stats. Identities = 119/322 (36%), Positives = 189/322 (58%), Gaps = 3/322 (0%) Query: 96 QVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFEN 155 + L E + + +++ YH + EI + M + ++ +V++ +G ++E Sbjct: 29 RSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYET 88 Query: 156 RPMNVLKFS--TGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDAL 213 P+ LK S +G K IW+D GIHAREW+ A W +I+ ++ + I +L L Sbjct: 89 HPIYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSRIRKLLRNL 148 Query: 214 DIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSD 273 D ++LPV N DGY+++ T +R+WRK+RS + C G D NRN++A + GAS N Sbjct: 149 DFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQ 208 Query: 274 SYHGPSANSEVEVKSIVDFIKS-HGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEV 332 ++ G SE E K++ FI+S + F+T+HSY QL++ PYGY K + E+ +V Sbjct: 209 TFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQV 268 Query: 333 AQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLP 392 QKAA +L++ +GT Y+VG ++Y +SG S DW+ D GI +S+ FELRD+G YGF+LP Sbjct: 269 GQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLP 328 Query: 393 ARQILPTAEETWLGLKAIMEHV 414 QI PT EET + ++++ V Sbjct: 329 EAQIQPTCEETMEAVLSVLDDV 350 >1CPB-B nrPDB Length = 217 Score = 343 bits (880), Expect = 7e-95, Method: Composition-based stats. Identities = 115/217 (52%), Positives = 153/217 (70%), Gaps = 1/217 (0%) Query: 203 DPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFG 262 + +T LD LD ++LPV N DGY+++ T NRMWRKTRS +GS C G D NRN+DAG+ Sbjct: 1 EIHMTEFLDKLDFYVLPVVNIDGYIYTWTTNRMWRKTRSTRAGSSCTGTDLNRNFDAGWC 60 Query: 263 GPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLMFPYGYKCT 321 GAS+NPCS++Y G +A SE E K++ DFI++H +KA++T+HSYSQ++++PY Y Sbjct: 61 SIGASNNPCSETYCGSAAESEKESKAVADFIRNHLSSIKAYLTIHSYSQMMLYPYSYDYK 120 Query: 322 KLDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFEL 381 + EL+ +A+ A + L SLHGT Y GP + IY ASGGS DW+YD GIKYSF FEL Sbjct: 121 LPKNNVELNTLAKGAVKKLASLHGTTYSYGPGATTIYPASGGSDDWAYDQGIKYSFTFEL 180 Query: 382 RDTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 418 RD GRYGF+LP QI PT EET L +K + +V +H Sbjct: 181 RDKGRYGFVLPESQIQPTCEETMLAIKYVTSYVLEHL 217 >2C1C-A nrPDB Length = 312 Score = 328 bits (842), Expect = 2e-90, Method: Composition-based stats. Identities = 106/302 (35%), Positives = 165/302 (54%), Gaps = 18/302 (5%) Query: 120 FGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST----GGDKPAIWLD 175 + Y LE I + +D + ++P + + VN SFE RP+ +K ST +KP I++D Sbjct: 3 YDNYQELEVIDEYLDYIGEKYPDVATVVNAAESFEGRPIKYIKISTTNFEDENKPVIFID 62 Query: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235 GIHAREW++ + W +K+V D ++ +L+ D LLPV NPDGY ++ T R Sbjct: 63 GGIHAREWISPPSVTWAIHKLVEDVTEN----DLLEKFDWILLPVVNPDGYKYTFTNERF 118 Query: 236 WRKTRSKVSGSL---CVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDF 292 WRKTRS + L C G D NRN+D + G S++PCSD Y G SA SEVE + + D Sbjct: 119 WRKTRSTNNNPLSQICRGADGNRNFDFVWNSIGTSNSPCSDIYAGTSAFSEVETRVVRDI 178 Query: 293 IKSH-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRS---LHGTKY 348 + H ++ ++T+HS+ ++++P+G+ + + L V A ++S + Y Sbjct: 179 LHEHLARMALYLTMHSFGSMILYPWGHDGSLSQNALGLHTVGVAMASVIQSNALPNFPPY 238 Query: 349 KVGPICSVI-YQASGGSIDWSYDYGIKYSFAFELR--DTGRYGFLLPARQILPTAEETWL 405 VG VI Y +G S D+++ G+ S+ +EL +G GF LP + I ETW Sbjct: 239 TVGNSALVIGYYIAGSSEDYAHSIGVPLSYTYELPGLSSGWDGFHLPPQYIEQVCRETWE 298 Query: 406 GL 407 G+ Sbjct: 299 GI 300 >3V7Z-A nrPDB Length = 326 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 95/312 (30%), Positives = 154/312 (49%), Gaps = 28/312 (8%) Query: 119 NFG-AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS----TGGDKPAIW 173 ++ YH E+ +++ + + +P +V K +IG S+E R + +K S T ++P + Sbjct: 4 SYDSGYHNYNEMVNKINTVASNYPNIVKKFSIGKSYEGRELWAVKISDNVGTDENEPEVL 63 Query: 174 LDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDG--YVFSQT 231 A HARE +T AL+T + +Y D IT++++ +I+++ NPDG Y S Sbjct: 64 YTALHHAREHLTVEMALYTLDLFTQNYNLDSRITNLVNNREIYIVFNINPDGGEYDISSG 123 Query: 232 KNRMWRKTRSKVSGSLCVGVDPNRNWDAGF-GGPGASSNPCSDSYHGPSANSEVEVKSIV 290 + WRK R SGS VG D NRN+ + G+S +P S++Y G SA S E ++ Sbjct: 124 SYKSWRKNRQPNSGSSYVGTDLNRNYGYKWGCCGGSSGSPSSETYRGRSAFSAPETAAMR 183 Query: 291 DFIKSH-----GKVKAFITLHSYSQLLMFPYGYKCTKL------DDFDELSEVAQKAAQS 339 DFI S ++K IT H+YS+L+++PYGY T + DDF+ +A AQ Sbjct: 184 DFINSRVVGGKQQIKTLITFHTYSELILYPYGYTYTDVPSDMTQDDFNVFKTMANTMAQ- 242 Query: 340 LRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPT 399 T S +Y G DW+Y ++F FE+ T P +++ Sbjct: 243 ------TNGYTPQQASDLYITDGDMTDWAYGQHKIFAFTFEMYPTSYNPGFYPPDEVI-- 294 Query: 400 AEETWLGLKAIM 411 ET +A++ Sbjct: 295 GRETSRNKEAVL 306 >1QMU-A nrPDB Length = 380 Score = 227 bits (578), Expect = 7e-60, Method: Composition-based stats. Identities = 58/281 (20%), Positives = 109/281 (38%), Gaps = 42/281 (14%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177 +H ++ + E+P + ++G S E R + V++ S +P Sbjct: 10 HHHFSDMEIFLRRYANEYPSITRLYSVGKSVELRELYVMEISDNPGIHEAGEPEFKYIGN 69 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 +H E V + L + ++G DP +T ++ + I ++P NPDGY SQ +R Sbjct: 70 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVQSTRIHIMPSMNPDGYEKSQEGDR--- 126 Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHG 297 V + D NRN+ D + + + E +++ ++K++ Sbjct: 127 --GGTVGRNNSNNYDLNRNF--------------PDQFFQVTDPPQPETLAVMSWLKTYP 170 Query: 298 KVKAFITLHSYSQLLMFPY-------GYKCTKLDD--FDELSEVAQKAAQSL------RS 342 V + LH S ++ +P+ DD F +L+ K + + + Sbjct: 171 FVLS-ANLHGGSLVVNYPFDDDEQGIAIYSKSPDDAVFQQLALSYSKENKKMYQGSPCKD 229 Query: 343 LHGTKYKVGPICSVI--YQASGGSIDWSYDYGIKYSFAFEL 381 L+ T+Y I + Y GG DW+Y + EL Sbjct: 230 LYPTEYFPHGITNGAQWYNVPGGMQDWNYLNTNCFEVTIEL 270 >2NSM-A nrPDB Length = 439 Score = 192 bits (487), Expect = 3e-49, Method: Composition-based stats. Identities = 62/292 (21%), Positives = 115/292 (39%), Gaps = 40/292 (13%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177 +H +++ + + + E PG+ +IG S E R + VL+FS +P + Sbjct: 6 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 65 Query: 178 IHAREWVTQATALWTANKIVSDY-GKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 236 +H E + + L + + ++ ++ I ++ I +LP NPDGY + + Sbjct: 66 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP-- 123 Query: 237 RKTRSKVSGSLCVGVDPNRNW---------DAGFGGPGASSNPCSDSYHGPSANSEVEVK 287 K V + GVD NRN+ + +GGP P D++ + E E + Sbjct: 124 NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHL-PLPDNW---KSQVEPETR 179 Query: 288 SIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCT-------------KLDD--FDELSEV 332 +++ ++ S V + LH + + +PY DD F +L++V Sbjct: 180 AVIRWMHSFNFVLS-ANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKV 238 Query: 333 AQKAAQSLRSLHGT-KYKVGPICSVI--YQASGGSIDWSYDYGIKYSFAFEL 381 A + Y I + Y S G D++Y + + EL Sbjct: 239 YSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLEL 290 >1UWY-A nrPDB Length = 426 Score = 191 bits (486), Expect = 4e-49, Method: Composition-based stats. Identities = 53/282 (18%), Positives = 101/282 (35%), Gaps = 42/282 (14%) Query: 122 AYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDA 176 YH E + + + + + +IG S + R + VL + P A Sbjct: 4 NYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVA 63 Query: 177 GIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 236 +H E V + L + +V+ GKDP IT+++++ I ++P NPDG+ + + + Sbjct: 64 NMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYY 123 Query: 237 RKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH 296 R + D NRN+ F S + E +++ ++K+ Sbjct: 124 SIGRENYN-----QYDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLKTE 164 Query: 297 GKVKAFITLHSYSQLLMFPYG---------YKCTKLDDFDELSEVAQKAA------QSLR 341 V + LH + + +P+ Y + D D +A A + Sbjct: 165 TFVLS-ANLHGGALVASYPFDNGVQATGALYSRSLTPDDDVFQYLAHTYASRNPNMKKGD 223 Query: 342 SLHGTKYKVGPICSVI--YQASGGSIDWSYDYGIKYSFAFEL 381 + + Y GG D++Y + + EL Sbjct: 224 ECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWAQCFEITLEL 265 >3MN8-A nrPDB Length = 435 Score = 172 bits (437), Expect = 2e-43, Method: Composition-based stats. Identities = 58/279 (20%), Positives = 104/279 (37%), Gaps = 32/279 (11%) Query: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGDK-----PAIWLDAG 177 Y + E++ L +P +G S E R + L+ S P + A Sbjct: 40 YASQEQLEDLFAGLEKAYPNQAKVHFLGRSLEGRNLLALQISRNTRSRNLLTPPVKYIAN 99 Query: 178 IHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWR 237 +H E V + ++ A ++ ++ + + ++++ DI+L+P NPDGY SQ N Sbjct: 100 MHGDETVGRQLLVYMAQYLLGNHERISDLGQLVNSTDIYLVPTMNPDGYALSQEGNCESL 159 Query: 238 KTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANS-EVEVKSIVDFIKSH 296 V +D NR++ H A S + E ++V++I S Sbjct: 160 PN--YVGRGNAANIDLNRDFPDRLEQSHV---------HQLRAQSRQPETAALVNWIVSK 208 Query: 297 GKVKAFITLHSYSQLLMFPYGYK---------CTKLDD--FDELSEVAQKAAQSLRSLHG 345 V + H + + +PY DD F +L+ +R + Sbjct: 209 PFVLS-ANFHGGAVVASYPYDNSLAHNECCEESLTPDDRVFKQLAHTYSDNHPIMRKGNN 267 Query: 346 -TKYKVGPICSVI--YQASGGSIDWSYDYGIKYSFAFEL 381 G I + Y+ SGG D++Y + + EL Sbjct: 268 CNDSFSGGITNGAHWYELSGGMQDFNYAFSNCFELTIEL 306 >1PYT-A nrPDB Length = 94 Score = 137 bits (346), Expect = 7e-33, Method: Composition-based stats. Identities = 52/94 (55%), Positives = 67/94 (71%) Query: 19 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVK 78 E FVG QVL I ++E +++ + +LE EHLQLDFW+ P PG VRVPF ++QAVK Sbjct: 1 KEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPGSPIDVRVPFPSLQAVK 60 Query: 79 VFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRR 112 VFLE+ GI Y IMIEDVQ LLD+E E+M ++ R Sbjct: 61 VFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSR 94 >3K2K-A nrPDB Length = 403 Score = 126 bits (316), Expect = 2e-29, Method: Composition-based stats. Identities = 54/243 (22%), Positives = 83/243 (34%), Gaps = 42/243 (17%) Query: 100 DKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMN 159 D + + + F Y EE E V + P S V +G + E RPM+ Sbjct: 110 DGQMLTIDHTPEFDSIHYAYFEPYS--EERHSEFLGAVQQMP-QASVVELGRTVEGRPMS 166 Query: 160 VLKFST----GGDKPAIWLDAGIHAREWVTQATALWTANKIV--SDYGKDPSITSILDAL 213 ++ T G K +W+ A H E + + ++V D+ DP + D Sbjct: 167 LVVLGTPDEAGAAKKKVWIIARQHPGESMAEWFIEGLVKRLVGWGDWSGDPVARKLYDHA 226 Query: 214 DIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSD 273 +++P NPDG V + G + NR W P A +P Sbjct: 227 TFYIVPNMNPDGSVHGNLRTN-------------AAGANLNREWME----PDAERSP--- 266 Query: 274 SYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVA 333 EV + D I + G F +H + L + + L F E V Sbjct: 267 -----------EVLVVRDAIHAIG-CDLFFDIHG-DEDLPYVFAAGSEMLPGFTEQQRVE 313 Query: 334 QKA 336 Q A Sbjct: 314 QSA 316 >4B6Z-A nrPDB Length = 405 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 60/279 (21%), Positives = 92/279 (32%), Gaps = 55/279 (19%) Query: 120 FGAYHTL--EEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST----GGDKPAIW 173 + AY EE V + P S V +G + E RPM++L T G K +W Sbjct: 128 YYAYFEPYSEERHAAFLGAVQQLP-QASVVELGRTVEGRPMSLLTLGTPETDGAPKKKVW 186 Query: 174 LDAGIHAREWVTQATALWTANKIV--SDYGKDPSITSILDALDIFLLPVTNPDGYVFSQT 231 + A H E + + ++ D+ DP + D + ++P NPDG V Sbjct: 187 IIARQHPGESMAEWFVEGLVKRLAGWGDWAGDPVARKLYDRVTFHIVPNMNPDGSVHGNL 246 Query: 232 KNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVD 291 + G + NR W A P A +P EV ++ D Sbjct: 247 RTN-------------AAGANLNREWMA----PDAERSP--------------EVLAVRD 275 Query: 292 FIKSHGKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVG 351 I + G F +H + L + + L F E Q A + ++ Sbjct: 276 AIHAIG-CDMFFDIHG-DEDLPYVFVAGSEMLPSFTEQQGKEQTAFIEAFKVASPDFQTE 333 Query: 352 PICSVIYQASGGSIDWSYDYGIKY--------SFAFELR 382 Y AS D + KY S E+ Sbjct: 334 HG----YAASKYKED-ALKLASKYIGHQFGCLSLTLEMP 367 >1O6X-A nrPDB Length = 81 Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats. Identities = 78/79 (98%), Positives = 78/79 (98%) Query: 18 CLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV 77 LETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV Sbjct: 3 SLETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAV 62 Query: 78 KVFLESQGIAYSIMIEDVQ 96 KVFLESQGIAYSIMIEDVQ Sbjct: 63 KVFLESQGIAYSIMIEDVQ 81 >3L2N-A nrPDB Length = 395 Score = 117 bits (294), Expect = 6e-27, Method: Composition-based stats. Identities = 61/300 (20%), Positives = 107/300 (35%), Gaps = 60/300 (20%) Query: 22 FVGDQVLEIVPSNEEQIKN-LLQLEAQEHLQLDFWKSPTTPGETAHVRVPFVNVQAVKVF 80 F G + I +N + I+ + E Q ++ T G+T + Sbjct: 26 FDGGNIETISLANPDDIQLAIRPDAGGEFYQWFNFRFEATIGKTYTL-----------NI 74 Query: 81 LESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFG----------AYHTLEEIS 130 L + G +Y ED Q + + + + G + AY T Sbjct: 75 LNAGGASYLKGWEDYQAVASYDRQTWFRLPTEYKDGKLSISVELDCEAIQIAYFTPYSYE 134 Query: 131 QEMDNL--VAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-KPAIWLDAGIHAREWVTQA 187 + +D + V HP LVS ++G + + R M ++K K +IW+ A H E + + Sbjct: 135 RHLDLISAVQLHP-LVSTEHLGLTLDGRDMTLVKVGDDDPSKKSIWITARQHPGETMAEW 193 Query: 188 TALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSL 247 N+++ + P+ ++LD + +++P NPDG V + Sbjct: 194 LVEGLLNQLLDN--DCPTSKALLDKANFYIVPNMNPDGSVRGHLRTN------------- 238 Query: 248 CVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHS 307 VG + NR W PS EV +V+ + G V F +H Sbjct: 239 AVGANLNREWQT------------------PSLERSPEVYYVVNKMHETG-VDLFYDVHG 279 >1CPB-A nrPDB Length = 82 Score = 114 bits (284), Expect = 1e-25, Method: Composition-based stats. Identities = 25/82 (30%), Positives = 46/82 (56%), Gaps = 1/82 (1%) Query: 115 SGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFST-GGDKPAIW 173 + ++ Y+ E I + + +E+P L+S+ IG++F + +LK G +KPA++ Sbjct: 1 TTGHSYEKYNNWETIEAWTEQVASENPDLISRSAIGTTFLGNTIYLLKVGKPGSNKPAVF 60 Query: 174 LDAGIHAREWVTQATALWTANK 195 +D G HAREW++ A W + Sbjct: 61 MDCGFHAREWISPAFCQWFVRE 82 >1PBA-A nrPDB Length = 81 Score = 94.4 bits (233), Expect = 8e-20, Method: Composition-based stats. Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 6/79 (7%) Query: 20 ETFVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKS----PTTPGETAHVRVPFVNVQ 75 E F G++V + +E I L +L + Q+DFWK P T RV ++ Sbjct: 5 EHFEGEKVFRVNVEDENDISELHELASTR--QIDFWKPDSVTQIKPHSTVDFRVKAEDIL 62 Query: 76 AVKVFLESQGIAYSIMIED 94 AV+ FLE + Y ++I + Sbjct: 63 AVEDFLEQNELQYEVLINN 81 >4A39-A nrPDB Length = 388 Score = 88.2 bits (217), Expect = 5e-18, Method: Composition-based stats. Identities = 36/188 (19%), Positives = 65/188 (34%), Gaps = 36/188 (19%) Query: 122 AYHTLEEISQEMDNLVAEHP-GLVSKVNIGSSFENRPMNVLKFSTGGDKP-AIWLDAGIH 179 AY + + V ++ +G+S + R + +L+ D +W+ A H Sbjct: 121 AYFEPYSRERHARLVERALGIEGVERLAVGTSVQGRDIELLRVRRHPDSHLKLWVIAQQH 180 Query: 180 AREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKT 239 E + + ++ D + +L+ D++L+P NPDG + Sbjct: 181 PGEHMAEWFMEGLIERLQR--PDDTEMQRLLEKADLYLVPNMNPDGAFHGNLRTN----- 233 Query: 240 RSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKV 299 G D NR + P A +P EV + +K HG V Sbjct: 234 --------AAGQDLNR----AWLEPSAERSP--------------EVWFVQQEMKRHG-V 266 Query: 300 KAFITLHS 307 F+ +H Sbjct: 267 DLFLDIHG 274 >3B2Y-A nrPDB Length = 275 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 50/139 (35%), Gaps = 24/139 (17%) Query: 127 EEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLK-FSTGGDKPAIWLDAGIHAREWVT 185 +I L E L K N S ++ +N+ + S D P++ + +G H E Sbjct: 23 NDIDAFYAQLAEEVNRLGLKKNTLGSVDSFAINLYQSASQRSDLPSLLISSGFHGEEAAG 82 Query: 186 QATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSG 245 L + ++ + +++ LLP+ NP G+ NR Sbjct: 83 PWGMLHFLRGL---------QPALFERVNLSLLPLVNPTGFKAGHRFNRF---------- 123 Query: 246 SLCVGVDPNRNWDAGFGGP 264 G +PNR + G P Sbjct: 124 ----GENPNRGFTLENGKP 138 >2QVP-A nrPDB Length = 275 Score = 49.7 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 24/133 (18%), Positives = 48/133 (36%), Gaps = 30/133 (22%) Query: 144 VSKVNIGSSFEN----RPMNVLKF-STGGDKPAIWLDAGIHAREWVTQATALWTANKIVS 198 ++ +GS P+ +L+ P + + AG H E L +++ Sbjct: 35 TERLGLGSKILGQAGHHPLYLLQSPGQKAGLPNLLISAGFHGEESAGPWGLLHFLSQLDG 94 Query: 199 DYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNW- 257 + +++ +LP+ NP G+ N + G +PNR + Sbjct: 95 ---------ELFKRVNLSVLPLVNPTGFAKGHRFNEL--------------GENPNRGFF 131 Query: 258 -DAGFGGPGASSN 269 + G PGA ++ Sbjct: 132 IENGKAKPGADTS 144 >3IEH-A nrPDB Length = 276 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 40/104 (38%), Gaps = 23/104 (22%) Query: 170 PAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFS 229 P++ + AG H E L ++ +D + + +++ LLP+ NP G+ Sbjct: 67 PSLLISAGFHGEESAGPWGLLHFLSEASAD---------LFERVNLSLLPLVNPTGFSRG 117 Query: 230 QTKNRMWRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSD 273 N+ G +PNR + G P A+ + + Sbjct: 118 HRFNKY--------------GENPNRGFVFENGKPKANEHTSVE 147 >5HXD-A nrPDB Length = 237 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 25/160 (15%), Positives = 42/160 (26%), Gaps = 39/160 (24%) Query: 146 KVNIGSSFENRPMNVLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPS 205 + G S P+ + + + AG H E + T + + Sbjct: 17 TEHYGRSLLGAPLIWFPAPAASRESGL-ILAGTHGDENSSVVTLSCALRTLTPSLRRH-- 73 Query: 206 ITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAG----- 260 ++ NPDG N GVD NRN+ A Sbjct: 74 ----------HVVLCVNPDGCQLGLRAN--------------ANGVDLNRNFPAANWKEG 109 Query: 261 -----FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295 + + + G SE E +++ I Sbjct: 110 ETVYRWNSAAEERDVVLLT--GDKPGSEPETQALCQLIHR 147 >5Y10-C nrPDB Length = 321 Score = 37.4 bits (85), Expect = 0.011, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 53/141 (37%), Gaps = 21/141 (14%) Query: 289 IVDFIKSHGKVKAFITLHSY-SQLLMFPYGYKCT------KLDDFDELSEVAQKAAQSLR 341 + ++++H + + ++ SQ+ +P + D D L + K A+ Sbjct: 38 VSSWLRNHSQFQGYVGQRGGRSQVSYYPAENSYSRWSGLLSPCDADWLGMLVVKKAKGSD 97 Query: 342 SLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFEL--RDTGRYGFLLPARQIL-- 397 + G + G + W G + + EL D+G LLP+ ++L Sbjct: 98 MIVPGPSYKGKVFFE-RPTFDGYVGWGCGSGKSRTESGELCSSDSGTSSGLLPSDRVLWI 156 Query: 398 ---------PTAEETWLGLKA 409 P EET+L LK+ Sbjct: 157 GDVACQPMTPIPEETFLELKS 177 >4OKO-A nrPDB Length = 312 Score = 36.2 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 59/158 (37%), Gaps = 34/158 (21%) Query: 101 KENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNV 160 +E + L + ++RS +E +++ LV++ + + + + Sbjct: 17 EEKSQWLAEQNKKRSY---------QQEAEKKILALVSDF-DIDEYGQLDYPVGSYKLYA 66 Query: 161 LKFST-GGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLP 219 LK KP + + G+H E A+ A ++ +D +I +LP Sbjct: 67 LKTKNWDASKPYVLVTGGVHGYETSGVQGAISFAQTRALEFARD---------YNIVILP 117 Query: 220 VTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNW 257 +P GY T NR W +DPNR++ Sbjct: 118 CLSPWGYE---TINR-WNPN----------ALDPNRSF 141 >3FMC-A nrPDB Length = 368 Score = 33.9 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 51/121 (42%), Gaps = 20/121 (16%) Query: 145 SKVNIGSSFENRPMN--VLKFSTGGDKPAIWLDAGIHAREWVTQATALWTANKIVSDYGK 202 +V +G +P++ V +F G P++++ A +H E A ++ K++ Y Sbjct: 7 HEVRVGELAAGQPLSLPVYRFKGKGAGPSVYIQANVHGAEVQGNA-VIYQLMKLLEHY-- 63 Query: 203 DPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNW-DAGF 261 +L DI L+P+ NP G + + R GV+ NR + D GF Sbjct: 64 -----ELLG--DISLVPLANPLGINQKSGEFTLGR-------FDPITGVNWNREYLDHGF 109 Query: 262 G 262 Sbjct: 110 N 110 >4WXU-A nrPDB Length = 277 Score = 32.0 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 40/249 (16%), Positives = 73/249 (29%), Gaps = 67/249 (26%) Query: 183 WVTQATALWTANKIVSDYG---KDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKT 239 WV + L TA I YG +DP T Y ++Q WR Sbjct: 23 WVGEPLTLRTAETITGKYGVWMRDPKPT------------------YPYTQETT--WRID 62 Query: 240 RSKVSGSLCVGVDPNRNWDAGFGG-----PGASSNPCSDSYHGPSANSEVEVKSIVDFIK 294 D + G+ P + + Y G E ++++ + Sbjct: 63 TVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYEL 122 Query: 295 SHGKVKAFITLHSYSQLLMFPYGYK-----------------------------CTKLDD 325 + VKA + FPY + + Sbjct: 123 NTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDDAKGAIVLSKLNPE 182 Query: 326 FDELSE-----VAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFE 380 EL + + +++ + + GT Y V Y ++ +++++YD G S Sbjct: 183 NLELEQTWETNIRKQSVANAFIICGTLYTVSS-----YTSADATVNFAYDTGTGISKTLT 237 Query: 381 LRDTGRYGF 389 + RY + Sbjct: 238 IPFKNRYKY 246 >4U2L-A nrPDB Length = 510 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 29/82 (35%), Gaps = 14/82 (17%) Query: 209 ILDALDIFLLPVTN--------PDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNRNWDAG 260 ++ A D LP N P+G + + N MW T + S +G+D WD Sbjct: 293 LVRARDTGTLPNLNSEVGAGWGPNGNIMTARANHMWNPTGAHQSSIPALGIDA---WDNS 349 Query: 261 FGGPGASSNPCS---DSYHGPS 279 A P +++ Sbjct: 350 DSSVFAEIAPMPAGLETWVSLY 371 >4OZ5-A nrPDB Length = 155 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 5/58 (8%) Query: 113 ERSGNFNFGAYHTLEEISQEMDNLVA-EHPGLVSKVNIGSSFENRPMNVLKFSTGGDK 169 E SG+ F A H E I D + +HPG NI + E RP+ KF K Sbjct: 39 ETSGDTVFQAPHAYEVI----DQVGEIKHPGFAVLNNIAVTQEGRPLFENKFKNRAGK 92 >2G9D-A nrPDB Length = 350 Score = 29.7 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 26/74 (35%), Gaps = 5/74 (6%) Query: 133 MDNLVAEHPGLVSKV--NIGSSFENRPMNVLKF---STGGDKPAIWLDAGIHAREWVTQA 187 D+L +HP + V G + + VL+ T + + GIH E Sbjct: 12 FDSLDLDHPMVAQTVRTEQGVTLKLHQRGVLEVIPAQTDAATKNMVISCGIHGDETAPME 71 Query: 188 TALWTANKIVSDYG 201 + IVS + Sbjct: 72 LLDKWIDDIVSGFQ 85 >3AK8-A nrPDB Length = 167 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 7/46 (15%), Positives = 20/46 (43%) Query: 73 NVQAVKVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNF 118 ++ V+ L+ Y+++ DV+ + + +E + S + Sbjct: 110 DIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDL 155 >4UOO-A nrPDB Length = 459 Score = 28.1 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 33/83 (39%), Gaps = 15/83 (18%) Query: 264 PGASSNPCSDSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLHSYSQLLMFPYGYKCTKL 323 P + + D+Y + + VKS VD++K G L+ S ++M YG Sbjct: 242 PATTGDSSVDTYFQTARYLDESVKSFVDYLKKSG-------LYDNSVIIM--YGDHYGIS 292 Query: 324 DDFDELSEVAQKAAQSLRSLHGT 346 D+ +E + L + T Sbjct: 293 DNHEE------AMTKILGKDYNT 309 >3C0Q-A nrPDB Length = 301 Score = 27.8 bits (60), Expect = 8.6, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 35/83 (42%), Gaps = 3/83 (3%) Query: 273 DSYHGPSANSEVEVKSIVDFIKSHGKVKAFITLH--SYSQLLMFPYGYKCTKLDDFDELS 330 + +A + +++ I+ F HG I H ++ +FPY ++ ++ L Sbjct: 50 ERVREKAAENLRDLERILRFNADHGFALFRIGQHLIPFASHPLFPYDWEGAYEEELARLG 109 Query: 331 EVAQKAAQSLRSLHGTKYKVGPI 353 +A+ Q L S+H +Y Sbjct: 110 ALARAFGQRL-SMHPGQYVNPGS 131 >4LO5-B nrPDB Length = 433 Score = 27.8 bits (60), Expect = 9.0, Method: Composition-based stats. Identities = 22/123 (17%), Positives = 44/123 (35%), Gaps = 16/123 (13%) Query: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM---------WRKTRSKVSGS 246 I +Y + I I++ ++L N G +N + R+ SG+ Sbjct: 184 ISDNYTYN--IPGIVNNNPFYILFTVNTTGIYKINAQNNLPSLKIYEAIGSGNRNFQSGN 241 Query: 247 LCVGVDPNRNWDAGFGGPGASSNPC-----SDSYHGPSANSEVEVKSIVDFIKSHGKVKA 301 LC N+ GF P A S +Y+ + +++ + F + G ++ Sbjct: 242 LCDDDIKAINYITGFDSPNAKSYLVVLLNKDKNYYIRVPQTSSNIENQIQFKREEGDLRN 301 Query: 302 FIT 304 + Sbjct: 302 LMN 304 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.131 0.353 Lambda K H 0.267 0.0405 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,961,960 Number of Sequences: 36641 Number of extensions: 620904 Number of successful extensions: 1928 Number of sequences better than 10.0: 50 Number of HSP's better than 10.0 without gapping: 71 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1684 Number of HSP's gapped (non-prelim): 100 length of query: 419 length of database: 10,336,785 effective HSP length: 100 effective length of query: 319 effective length of database: 6,672,685 effective search space: 2128586515 effective search space used: 2128586515 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.7 bits)