BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P47998 (322 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2ISQ-A nrPDB 642 0.0 4AEC-A nrPDB 451 e-127 3VBE-A nrPDB 407 e-114 4LMA-A nrPDB 364 e-101 4LMB-A nrPDB 347 5e-96 2Q3D-A nrPDB 344 4e-95 4I1Y-A nrPDB 342 2e-94 5XA2-A nrPDB 317 3e-87 3T4P-A nrPDB 306 9e-84 5J5V-A nrPDB 306 1e-83 2EGU-A nrPDB 288 2e-78 5XCN-X nrPDB 277 4e-75 3FCA-A nrPDB 276 7e-75 2EFY-A nrPDB 263 7e-71 2PQM-A nrPDB 257 4e-69 2BHS-A nrPDB 247 4e-66 2JC3-A nrPDB 245 2e-65 5XW3-A nrPDB 242 1e-64 5XEM-A nrPDB 234 6e-62 4OFX-A nrPDB 224 5e-59 6AHI-A nrPDB 223 7e-59 1M54-A nrPDB 218 3e-57 4COO-A nrPDB 217 5e-57 5MMS-A nrPDB 217 7e-57 6C2H-A nrPDB 209 9e-55 5OHX-A nrPDB 209 1e-54 3X43-A nrPDB 206 1e-53 5B1I-A nrPDB 201 5e-52 3PC3-A nrPDB 192 2e-49 5JJC-A nrPDB 180 6e-46 5B55-A nrPDB 166 9e-42 5I7O-A nrPDB 163 1e-40 5D84-A nrPDB 148 3e-36 3VSD-A nrPDB 70 2e-12 5X2L-A nrPDB 52 3e-07 5KZM-B nrPDB 43 2e-04 3L6C-A nrPDB 41 8e-04 1TDJ-A nrPDB 38 0.007 3IAU-A nrPDB 38 0.007 5YGR-A nrPDB 37 0.011 4D9G-A nrPDB 37 0.013 6NMX-A nrPDB 36 0.019 2ZSJ-A nrPDB 35 0.031 1VE5-A nrPDB 35 0.033 5YBW-A nrPDB 35 0.058 5EY5-B nrPDB 34 0.079 2GN1-A nrPDB 33 0.15 2D1F-A nrPDB 33 0.17 1CX9-B nrPDB 32 0.50 3R0X-A nrPDB 32 0.50 1G3N-B nrPDB 31 0.60 1YB5-A nrPDB 31 0.87 1J71-A nrPDB 30 1.6 4NEG-A nrPDB 29 2.6 3SS9-X nrPDB 29 3.3 5OVJ-A nrPDB 28 3.6 5OVL-A nrPDB 28 3.6 3HOX-E nrPDB 28 3.7 6AMI-A nrPDB 28 3.9 1UZM-A nrPDB 28 6.3 1UIN-A nrPDB 28 7.1 3RLI-A nrPDB 28 7.8 3TK1-A nrPDB 27 8.3 5C3U-A nrPDB 27 8.7 5GT5-A nrPDB 27 9.9 >2ISQ-A nrPDB Length = 320 Score = 642 bits (1656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 320/320 (100%), Positives = 320/320 (100%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL Sbjct: 1 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 60 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA Sbjct: 61 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 120 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT Sbjct: 121 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 180 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 242 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE Sbjct: 181 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 240 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY Sbjct: 241 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 300 Query: 303 LSTVLFDATRKEAEAMTFEA 322 LSTVLFDATRKEAEAMTFEA Sbjct: 301 LSTVLFDATRKEAEAMTFEA 320 >4AEC-A nrPDB Length = 430 Score = 451 bits (1159), Expect = e-127, Method: Compositional matrix adjust. Identities = 226/317 (71%), Positives = 274/317 (86%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 IA +V++LIG TP+VYLN++A+GCV +AAKLE+MEPC SVKDRIG+SM++DAE+KG I Sbjct: 113 IADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFIS 172 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 PG+SVL+EPTSGNTG+GLAF AA++GY+LI+TMPASMS ERR++L AFG ELVLTDPAKG Sbjct: 173 PGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKG 232 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 M GA+ KAEEIL TP+ YMLQQF+NPANPKIHYETTGPEIW T GK+D FV+GIGTGG Sbjct: 233 MTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGG 292 Query: 185 TITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVV 244 TITG G+++KE+N ++ GVEP ES ILSGGKPGPHKIQGIGAGFIP L+ ++DEV+ Sbjct: 293 TITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVI 352 Query: 245 QVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLS 304 +SS+E+I+ A+QLALKEGL+VGISSGAAAAAAIK+A+RPENAGKL +FPSFGERYLS Sbjct: 353 AISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLS 412 Query: 305 TVLFDATRKEAEAMTFE 321 T LF + R+E E M E Sbjct: 413 TPLFQSIREEVEKMQPE 429 >3VBE-A nrPDB Length = 344 Score = 407 bits (1046), Expect = e-114, Method: Compositional matrix adjust. Identities = 194/317 (61%), Positives = 253/317 (79%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 ++ I K V++LIG TPLVYLN V EGC VA K EMM+P +S+KDR ++MI+DAE+K Sbjct: 22 STNIKKHVSQLIGRTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKN 81 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 LI PG++ LIEPTSGN G+ +AF AA KGYK+++TMP+ S ERR+ + AFG EL+LTDP Sbjct: 82 LITPGKTTLIEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDP 141 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 AKGM G + KA E+L TPN +MLQQF NPAN ++H+ETTGPEIW+ T G++D FV GIG Sbjct: 142 AKGMGGTVKKAYELLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNGQVDIFVMGIG 201 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 +GGT++G G+YLK +N NVK+YGVEP ES +L+GGKPGPH I G G GF P +L++D+++ Sbjct: 202 SGGTVSGVGQYLKSKNPNVKIYGVEPSESNVLNGGKPGPHHITGNGVGFKPDILDLDVME 261 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 +V++VSS+++++MAR LALKEGL+VGISSGA AA++LAQ PEN GKL V + PSFGER Sbjct: 262 KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALRLAQLPENKGKLIVTVHPSFGER 321 Query: 302 YLSTVLFDATRKEAEAM 318 YLS+VLF R+EAE M Sbjct: 322 YLSSVLFQELRQEAENM 338 >4LMA-A nrPDB Length = 326 Score = 364 bits (934), Expect = e-101, Method: Compositional matrix adjust. Identities = 189/308 (61%), Positives = 232/308 (75%), Gaps = 2/308 (0%) Query: 4 RIAKDVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 RIA DVTEL+G TPLV LN + AEGC+GR+ KLE M P +SVKDRIG MI+ AEK G Sbjct: 9 RIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKAG 68 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 LI P +VL+EPTSGNTG+ LA TAAAKGY+LI+TMP +MS ERR +L A+G L LT Sbjct: 69 LINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPG 128 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 ++GMKGAI +A++I+ P YMLQQF NP+NP+IH TT EIW+ T G++D V+G+G Sbjct: 129 SQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGVG 188 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGTITG + +K + + ++ VEP S ++SGG PGPHKIQGIGAGFIP VL DLID Sbjct: 189 TGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLID 248 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 EV+ VS +E+ R+LA +EGLL GISSGA AAI+LAQRPEN GKL V I PSFGER Sbjct: 249 EVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGER 308 Query: 302 YLSTVLFD 309 YLST++F Sbjct: 309 YLSTLMFQ 316 >4LMB-A nrPDB Length = 322 Score = 347 bits (889), Expect = 5e-96, Method: Compositional matrix adjust. Identities = 181/306 (59%), Positives = 225/306 (73%), Gaps = 2/306 (0%) Query: 5 IAKDVTELIGNTPLVYLNN--VAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 IA+D+T+L+G TPLV LN VAEG R+ KLE M P +SVKDRIG SM+ DAE GL Sbjct: 10 IARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGL 69 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 I P +++L+EPTSGNTG+ LA AAAKGY+L++TMP +MS ERR +L A+G +L LT + Sbjct: 70 IHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGS 129 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 +GM+GAI +AEEI+ TPN Y LQQF NPANPKIH ETT EIW T G +D + G+GT Sbjct: 130 QGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGT 189 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 242 GGTITG + +K + + VEP S +LSGG+PGPHKIQGIGAGFIP++ +LIDE Sbjct: 190 GGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELIDE 249 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 V+ V E+ AR+LA +EGLL GIS+GAA AAI++ +RPEN KL V I PSFGERY Sbjct: 250 VIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGERY 309 Query: 303 LSTVLF 308 LST LF Sbjct: 310 LSTALF 315 >2Q3D-A nrPDB Length = 313 Score = 344 bits (882), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 177/305 (58%), Positives = 233/305 (76%), Gaps = 3/305 (0%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 IA+D+T+LIG TPLV L V +G V + AKLE P +SVKDRIG +M+ AE+ GLIK Sbjct: 6 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 65 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 P +++++EPTSGNTG+ LA AA+GY+ ++TMP +MS ERR++L A+G EL+LT A G Sbjct: 66 P-DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 124 Query: 125 MKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 183 M GAIAKAEE LAKT Y + QQFENPANP IH TT E+W+ T GK+D V+G+GTG Sbjct: 125 MSGAIAKAEE-LAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTG 183 Query: 184 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 GTITG + +KE+ + + VEP S +LSGG+ GPH IQGIGAGF+P VL+ DL+DE+ Sbjct: 184 GTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEI 243 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 + V +++++++AR+LA +EGLLVGISSGAA AA+++A+RPENAGKL V + P FGERYL Sbjct: 244 ITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYL 303 Query: 304 STVLF 308 ST LF Sbjct: 304 STPLF 308 >4I1Y-A nrPDB Length = 314 Score = 342 bits (876), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 179/305 (58%), Positives = 232/305 (76%), Gaps = 3/305 (0%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 IA+++ +LIG TPLV L V +G V AKLE P S+KDRIG +MI AEK GLIK Sbjct: 7 IAENIAQLIGGTPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAGLIK 66 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 P +++++EPTSGNTG+ LA +AA+GYK ++TMP +MS ERR++L A+G ELVLT A+G Sbjct: 67 P-DTIILEPTSGNTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPGAEG 125 Query: 125 MKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 183 M GAIAKAEE LAKT + Y + QQFENPANP +H TT E+W+ T GK+D FVSG+GTG Sbjct: 126 MAGAIAKAEE-LAKTDDRYFIPQQFENPANPAVHAVTTAEEVWRDTDGKVDIFVSGVGTG 184 Query: 184 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 GTITG + +K++ + + VEP S +LSGG+ GPH IQGIGAGF+P VL++ L+DEV Sbjct: 185 GTITGVAQVIKQRRPSAQFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDLALVDEV 244 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 + V +D+++++AR++A +EGLL GISSGAA AA +LA RPENAGKL V + P FGERYL Sbjct: 245 ITVGNDDALELARRMATEEGLLFGISSGAAVWAARELAHRPENAGKLIVVVLPDFGERYL 304 Query: 304 STVLF 308 STVLF Sbjct: 305 STVLF 309 >5XA2-A nrPDB Length = 309 Score = 317 bits (813), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 174/309 (56%), Positives = 222/309 (71%), Gaps = 3/309 (0%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 I KD +E IG TPLV +N + G RV AK+E P SVK RIG +MI DAE+ G +K Sbjct: 3 IFKDNSESIGRTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGKLK 62 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 PG V +EPTSGNTG+ LAF AA+GYKL +TMP +MS ERR++L +FG +LVLT A G Sbjct: 63 PGMHV-VEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGADG 121 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 MKGAI+KAEE LA P ++ QQF+NPANP IH +TTGPEIW T G++D FV+G+GTGG Sbjct: 122 MKGAISKAEE-LAAQPGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTGG 180 Query: 185 TITGAGKYLK-EQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 TITG ++LK E+ V + VEP S +L+GG G HKIQGIGAGF+P + ++DE+ Sbjct: 181 TITGVARFLKHEKKHPVHVVAVEPAASPVLAGGPAGRHKIQGIGAGFVPDTFDRSVVDEI 240 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 + V+ DE+I+ AR+LA++EG+ GIS GAA A A+K+A RPE AGK V + P GERYL Sbjct: 241 LSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPDAGERYL 300 Query: 304 STVLFDATR 312 ST LF+ R Sbjct: 301 STALFENLR 309 >3T4P-A nrPDB Length = 334 Score = 306 bits (783), Expect = 9e-84, Method: Compositional matrix adjust. Identities = 158/317 (49%), Positives = 219/317 (69%), Gaps = 1/317 (0%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 + +A+ + +LIG TP +YLN + +V K+E P +SVKDR+GF++ AEK+G Sbjct: 8 SKNVAQSIDQLIGQTPALYLNKL-NNTKAKVVLKMECENPMASVKDRLGFAIYDKAEKEG 66 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 + PG+S+++E +SGNTGV LA A +GYK+IITMP SMS ERR +L FG E++LT Sbjct: 67 KLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEVILTPA 126 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 A GMKGA+A A++I+A PN + QF N IH ETTGPEIW+ T +D F++G+G Sbjct: 127 ALGMKGAVAMAKKIVAANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNVDCFIAGVG 186 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGT+TG + LK+ ++ ++ VEP ES +LSGGKPGPHKIQGIG GF+P VL+ LID Sbjct: 187 TGGTLTGVARALKKMGSHARIVAVEPTESPVLSGGKPGPHKIQGIGPGFVPDVLDRSLID 246 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 EV+ V+ D++I+ A +L +G+ G S GA AA+K+A+RPE GK V + PSFGER Sbjct: 247 EVLCVAGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEMEGKTIVTVIPSFGER 306 Query: 302 YLSTVLFDATRKEAEAM 318 YLST L+ + R E ++ Sbjct: 307 YLSTTLYRSVRDEVSSL 323 >5J5V-A nrPDB Length = 323 Score = 306 bits (783), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 172/314 (54%), Positives = 224/314 (71%), Gaps = 13/314 (4%) Query: 4 RIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLI 63 +I +D + IG+TPLV LN + G R+ AK+E P SVK RIG +MI DAEK+G++ Sbjct: 3 KIFEDNSLTIGHTPLVRLNRIGNG---RILAKVESRNPSFSVKCRIGANMIWDAEKRGVL 59 Query: 64 KPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 123 KPG L+EPTSGNTG+ LA+ AAA+GYKL +TMP +MS ERR +L A G LVLT+ AK Sbjct: 60 KPGVE-LVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAK 118 Query: 124 GMKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 GMKGAI KAEEI+A P Y+L QQF NPANP+IH +TTGPEIW+ T G++D F++G+GT Sbjct: 119 GMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGT 178 Query: 183 GGTITGAGKYLKEQNANVKL--YGVEPVESAILSGG------KPGPHKIQGIGAGFIPSV 234 GGT+TG +Y+K L VEP +S +++ KPGPHKIQGIGAGFIP+ Sbjct: 179 GGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPAN 238 Query: 235 LNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAI 294 L++ L+D+V+ ++++E+I AR+L +EG+L GISSGAA AAA+KL + K V I Sbjct: 239 LDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVI 298 Query: 295 FPSFGERYLSTVLF 308 PS GERYLST LF Sbjct: 299 LPSSGERYLSTALF 312 >2EGU-A nrPDB Length = 308 Score = 288 bits (737), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 174/307 (56%), Positives = 226/307 (73%), Gaps = 5/307 (1%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 +R +TELIG+TP V LN + + V KLE M P SSVKDRI +MI AEK G Sbjct: 2 ARTVNSITELIGDTPAVKLNRIVDEDSADVYLKLEFMNPGSSVKDRIALAMIEAAEKAGK 61 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 +KPG+++ +EPTSGNTG+GLA AAAKGYK ++ MP +MS ERR +L A+G ELVLT A Sbjct: 62 LKPGDTI-VEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGA 120 Query: 123 KGMKGAIAKAEEILAKTPNGY-MLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 +GM+GAIAKAEE++ + +GY M QQF+N ANP+IH TTG EI + G ++D FV+G+G Sbjct: 121 QGMRGAIAKAEELVRE--HGYFMPQQFKNEANPEIHRLTTGKEIVEQMGDQLDAFVAGVG 178 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGTITGAGK L+E N+K+Y VEP +S +LSGGKPGPHKIQGIGAGF+P +L+ + D Sbjct: 179 TGGTITGAGKVLREAYPNIKIYAVEPADSPVLSGGKPGPHKIQGIGAGFVPDILDTSIYD 238 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 V+ V+++E+ AR+ A +EG+L GISSGAA AA+K+A+ GK +AI PS GER Sbjct: 239 GVITVTTEEAFAAARRAAREEGILGGISSGAAIHAALKVAKE-LGKGKKVLAIIPSNGER 297 Query: 302 YLSTVLF 308 YLST L+ Sbjct: 298 YLSTPLY 304 >5XCN-X nrPDB Length = 350 Score = 277 bits (709), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 172/313 (54%), Positives = 216/313 (69%), Gaps = 11/313 (3%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 I D + IGNTPLV L + G G V K+E P SVK RIG +M+ AEK G + Sbjct: 37 IYADNSYSIGNTPLVRLKHF--GHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDGTLT 94 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 G+ + ++ TSGNTG+ LA+ AAA+GYK+ +TMP +MS ER+ +L GV LVLT+ AKG Sbjct: 95 KGKEI-VDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEGAKG 153 Query: 125 MKGAIAKAEEILAKTPNGY-MLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 183 KGAIAKAEEI+A P+ Y ML+QFENPANP+IH ETTGPEIWK T GK+D V+G+GTG Sbjct: 154 AKGAIAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGVGTG 213 Query: 184 GTITGAGKYLK-EQNANVKLYGVEPVESAILSGG------KPGPHKIQGIGAGFIPSVLN 236 G+ITG + +K + + VEPVES ++S KPGPHKIQGIGAGFIP L+ Sbjct: 214 GSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPKNLD 273 Query: 237 VDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFP 296 + +ID V V SD ++ AR+L +EG+L GISSGAA AAA +LA+ PE A KL V I P Sbjct: 274 LSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVVILP 333 Query: 297 SFGERYLSTVLFD 309 S ERYLST LF+ Sbjct: 334 SASERYLSTALFE 346 >3FCA-A nrPDB Length = 291 Score = 276 bits (707), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 155/297 (52%), Positives = 201/297 (67%), Gaps = 10/297 (3%) Query: 11 ELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVL 70 LIG+TP+V L+++ R+A KLE P SVKDR MI DAEK+GL+K G + Sbjct: 4 RLIGSTPIVRLDSIDS----RIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKNG---I 56 Query: 71 IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIA 130 +EPTSGN G+ +A A +G+++I+TMP +MS ERR +L G ELVLT GMKGA+ Sbjct: 57 VEPTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLTPGELGMKGAVE 116 Query: 131 KAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAG 190 KA EI +T +ML QFENP N H TTGPEI K +ID FV+G+GTGGTI+G G Sbjct: 117 KALEISRET-GAHMLNQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISGVG 175 Query: 191 KYLKEQNAN-VKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSD 249 + LK N VK+ VEP +S +LSGG+PG H IQGIGAGF+P +L+ +IDEV+ V + Sbjct: 176 RVLKGFFGNGVKIVAVEPAKSPVLSGGQPGKHAIQGIGAGFVPKILDRSVIDEVITVEDE 235 Query: 250 ESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 E+ +MAR LA KEGLLVGISSGA AAA+K+AQ+ ++ V + P ERYLS + Sbjct: 236 EAYEMARYLAKKEGLLVGISSGANVAAALKVAQKLGPDARV-VTVAPDHAERYLSIL 291 >2EFY-A nrPDB Length = 304 Score = 263 bits (672), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 151/297 (50%), Positives = 203/297 (68%), Gaps = 3/297 (1%) Query: 13 IGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGE-SVLI 71 IG TP+V L V E + V KLE + P S+KDR + MI DAE++G+++PG V++ Sbjct: 7 IGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGILRPGSGQVIV 66 Query: 72 EPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAK 131 EPTSGNTG+GLA AA++GY+LI+TMPA MS ER+ +L AFG ELVLTDP + M A + Sbjct: 67 EPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRMLAAREE 126 Query: 132 AEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGK 191 A L + +M QF+NPAN + HYETTGPE+++ G+ID FV G GTGGTITG G+ Sbjct: 127 ALR-LKEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGTGGTITGVGR 185 Query: 192 YLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDES 251 YLKE+ +VK+ VEP S +LSGGK G H QG+G GFIP L++ L+D V+QV +++ Sbjct: 186 YLKERIPHVKVIAVEPARSNVLSGGKMGQHGFQGMGPGFIPENLDLSLLDGVIQVWEEDA 245 Query: 252 IDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLF 308 +AR+LA +EGL +G+SSG AA+++A R GK I P G +YLST L+ Sbjct: 246 FPLARRLAREEGLFLGMSSGGIVWAALQVA-RELGPGKRVACISPDGGWKYLSTPLY 301 >2PQM-A nrPDB Length = 343 Score = 257 bits (657), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 143/310 (46%), Positives = 198/310 (63%), Gaps = 7/310 (2%) Query: 4 RIAKDVTELIGNTPLVYLNNVAEGCV----GRVAAKLEMMEPCSSVKDRIGFSMISDAEK 59 RI ++ E IG TPLV L+ V E R+ KLE P SSVKDR+GF+++ A K Sbjct: 12 RIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAIK 71 Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 G +KPG + IE TSGNTG+ L A GY++ I MP++MS ER++I+ AFG EL+LT Sbjct: 72 DGRLKPGMEI-IESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELILT 130 Query: 120 DPAKGMKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVS 178 + KGM GAI + +++ + P Y + QF NP N H+ T EIW+ T G++D VS Sbjct: 131 EGKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHYTAN-EIWEDTDGEVDIVVS 189 Query: 179 GIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVD 238 +GT GT+ G + LKE+ +K+ VEP ESA+L G GPH IQGIGAGFIP + + Sbjct: 190 AVGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKKE 249 Query: 239 LIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSF 298 +DE++ + + ++ MAR + +G++ G+SSGAA A +K A++PEN GK V I PS Sbjct: 250 FVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPSC 309 Query: 299 GERYLSTVLF 308 GERYLST L+ Sbjct: 310 GERYLSTDLY 319 >2BHS-A nrPDB Length = 303 Score = 247 bits (631), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 134/298 (44%), Positives = 187/298 (62%), Gaps = 11/298 (3%) Query: 11 ELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVL 70 + IGNTPLV L + V KLE P SVKDR SMI +AEK+G IKPG+ VL Sbjct: 6 QTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGD-VL 64 Query: 71 IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIA 130 IE TSGNTG+ LA AA KGY++ + MP +MS ERR + A+G EL+L +GM+GA Sbjct: 65 IEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARD 124 Query: 131 KAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAG 190 A E +A G +L QF NP NP HY TTGPEIW+ TGG+I FVS +GT GTITG Sbjct: 125 LALE-MANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGTITGVS 183 Query: 191 KYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDE 250 ++++EQ+ V + G++P E + + G + P + ++P + N L+DEV+ + + Sbjct: 184 RFMREQSKPVTIVGLQPEEGSSIPGIRRWPTE-------YLPGIFNASLVDEVLDIHQRD 236 Query: 251 SIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLF 308 + + R+LA++EG+ G+SSG A A A+++A+ N + VAI G+RYLST +F Sbjct: 237 AENTMRELAVREGIFCGVSSGGAVAGALRVAK--ANPDAVVVAIICDRGDRYLSTGVF 292 >2JC3-A nrPDB Length = 303 Score = 245 bits (625), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 132/298 (44%), Positives = 186/298 (62%), Gaps = 11/298 (3%) Query: 11 ELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVL 70 + IGNTPLV L + + KLE P SVKDR SMI +AEK+G IKPG+ VL Sbjct: 6 QTIGNTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGD-VL 64 Query: 71 IEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIA 130 IE TSGNTG+ LA AA KGY++ + MP +MS ERR + A+G EL+L +GM+GA Sbjct: 65 IEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARD 124 Query: 131 KAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAG 190 A +++ G +L QF NP NP HY TTGPEIW+ T G+I FVS +GT GTITG Sbjct: 125 LAL-AMSERGEGKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGTITGVS 183 Query: 191 KYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDE 250 ++L+EQ V + G++P E + + G + P A ++P + N L+DEV+ + ++ Sbjct: 184 RFLREQEKPVTIVGLQPEEGSSIPGIRRWP-------AEYMPGIFNASLVDEVLDIHQND 236 Query: 251 SIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLF 308 + + R+LA++EG+ G+SSG A A A+++A+ G + VAI G+RYLST +F Sbjct: 237 AENTMRELAVREGIFCGVSSGGAVAGALRVAR--ATPGAIVVAIICDRGDRYLSTGVF 292 >5XW3-A nrPDB Length = 315 Score = 242 bits (618), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 136/307 (44%), Positives = 191/307 (62%), Gaps = 7/307 (2%) Query: 4 RIAKDVTELIGNTPLVYLNNVA--EGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 + + V ELIG+TP+V + + EG R+ AKLE P SVKDR+G +I DA +KG Sbjct: 2 NVYRGVHELIGHTPIVEITRFSLPEGV--RLFAKLEFYNPGGSVKDRLGRELIEDALEKG 59 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 L+ G ++ IEPT+GNTG+GLA A ++I+ +P S E++ ++ A G +V T Sbjct: 60 LVTEGGTI-IEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPT 118 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 +GM GAIAKA+E++ + PN Y QF N ANP+ +++T GPE+W G+I+ FV+G G Sbjct: 119 EQGMTGAIAKAKELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAG 178 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGT G YLKE+N ++K VEP E +IL+GGK G H+ +GIG FIP L D Sbjct: 179 TGGTFMGTASYLKEKNIDIKTVIVEP-EGSILNGGKAGSHETEGIGLEFIPPFLKTSYFD 237 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 E+ +S + ++LA KEGLLVG SSGAA A++ A++ G V IFP ER Sbjct: 238 EIHTISDRNAFLRVKELAQKEGLLVGSSSGAAFHASLLEAEKAA-PGTNIVTIFPDSSER 296 Query: 302 YLSTVLF 308 YLS ++ Sbjct: 297 YLSKDIY 303 >5XEM-A nrPDB Length = 310 Score = 234 bits (596), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 137/304 (45%), Positives = 188/304 (61%), Gaps = 4/304 (1%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 +A V +LIGNTPLV +NN+ + + KLE P S KDRI MI +AEK+GLI Sbjct: 6 LANSVIDLIGNTPLVKINNI-DTFGNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLID 64 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 ++V+IE TSGNTG+GLA A K YKL I MP +MS ER ++ A+G E++LTD + G Sbjct: 65 K-DTVIIEATSGNTGIGLAMICAVKNYKLKIVMPDTMSIERIQLMRAYGTEVILTDGSLG 123 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 MK + K EE+ ++ QF N NPK HYETT EI K K+D F+ G GTGG Sbjct: 124 MKACLEKLEELKKNEKKYFVPNQFTNVNNPKAHYETTAEEILKDLNNKVDVFICGTGTGG 183 Query: 185 TITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGA--GFIPSVLNVDLIDE 242 + +G K LKE+ N+K + VEP S +LS G GPHKIQG+G G IP+V + L D+ Sbjct: 184 SFSGTAKKLKEKLPNIKTFPVEPASSPLLSKGYIGPHKIQGMGMSIGGIPAVYDGSLADD 243 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 ++ D++ +M R+L+ KEG+L GIS+GA AA+ ++ + G V + GE+Y Sbjct: 244 ILVCEDDDAFEMMRELSFKEGILGGISTGATFKAALDYSKENADKGLKIVVLSTDSGEKY 303 Query: 303 LSTV 306 LS + Sbjct: 304 LSNI 307 >4OFX-A nrPDB Length = 319 Score = 224 bits (570), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 135/316 (42%), Positives = 195/316 (61%), Gaps = 13/316 (4%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + ++ ++IG TP+V L+ + + + K E + P SVKDRIG +MI AEK+G IK Sbjct: 5 VLDNILQVIGKTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESAEKQGKIK 64 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT----- 119 PG++ LIEPTSGNTG+G+A A KGY++IITMP MS E++++L A G + T Sbjct: 65 PGDT-LIEPTSGNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAA 123 Query: 120 --DPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 DP + I+ A+ + + PN Y+L Q+ N NP IHY+TTG EI G + V Sbjct: 124 YDDP----ESHISLAKRLNQEIPNSYILDQYSNAENPDIHYQTTGQEILDDMGENLSMVV 179 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNV 237 G+GTGGTI G K LKE N ++++ GV+P+ S + G + P+ ++GIG FIP VL+ Sbjct: 180 MGVGTGGTIIGVAKKLKEVNPSIQIIGVDPIGSILGGGDEIKPYLVEGIGYDFIPEVLDN 239 Query: 238 DLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPS 297 +LIDE ++++ +S MAR+L +EGLLVG SSG+A AA + AQR + + V I P Sbjct: 240 NLIDEYIKINDKDSFLMARRLIREEGLLVGGSSGSAVWAACQAAQRLKEGERCLV-ILPD 298 Query: 298 FGERYLSTVLFDATRK 313 YL+ + DA K Sbjct: 299 AIRNYLTKFVDDAWMK 314 >6AHI-A nrPDB Length = 314 Score = 223 bits (569), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 133/308 (43%), Positives = 183/308 (59%), Gaps = 9/308 (2%) Query: 5 IAKDVTELIGNTPLVYLNN--VAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 I + + IG TP+ N + AKLE + P SVKDR+G +I + K G Sbjct: 3 IITTMQDAIGRTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGK 62 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 I ++ +IEPT+GNTG+ LA A K I +P STE++ I+ A G ++ T + Sbjct: 63 IT-SKTTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPTS 121 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 +G+ GAI K++E+ P+ Y+ QFENP NP +Y T PEI + G + FV+GIG+ Sbjct: 122 EGISGAIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGIGS 181 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVL-NVDLID 241 GGT G +YLKE+ ++L GVEP E +IL+GG+PGPH+I+GIG FIP N+D ID Sbjct: 182 GGTFAGTARYLKERIPAIRLIGVEP-EGSILNGGEPGPHEIEGIGVEFIPPFFENLD-ID 239 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQR-PENAGKLFVAIFPSFGE 300 +S +E R+LA K GLLVG SSGAA AA+K AQR PE G + IFP + Sbjct: 240 GFETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKEAQRLPE--GSQVLTIFPDVAD 297 Query: 301 RYLSTVLF 308 RYLS ++ Sbjct: 298 RYLSKGIY 305 >1M54-A nrPDB Length = 363 Score = 218 bits (554), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 123/317 (38%), Positives = 185/317 (58%), Gaps = 14/317 (4%) Query: 4 RIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 +I D+ + IG+TP+V +N + + G + AK E SVKDRI MI DAE+ G Sbjct: 32 KILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAERDG 91 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 +KPG+++ IEPTSGNTG+GLA AA +GY+ II MP MS+E+ +L A G E+V T P Sbjct: 92 TLKPGDTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT-P 149 Query: 122 AKGM----KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 + + A + + PN ++L Q+ N +NP HY+TT EI + GK+D V Sbjct: 150 TNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDMLV 209 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEP-----VESAILSGGKPGPHKIQGIGAGFIP 232 + +GTGGTITG + LKE+ ++ GV+P E L+ + ++++GIG FIP Sbjct: 210 ASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFIP 269 Query: 233 SVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFV 292 +VL+ ++D+ + + +E+ AR L +EGLL G S+G+ A A+K AQ + G+ V Sbjct: 270 TVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQE-GQRCV 328 Query: 293 AIFPSFGERYLSTVLFD 309 I P Y++ L D Sbjct: 329 VILPDSVRNYMTKFLSD 345 >4COO-A nrPDB Length = 563 Score = 217 bits (553), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 123/319 (38%), Positives = 186/319 (58%), Gaps = 14/319 (4%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEK 59 + +I D+ + IG+TP+V +N + + G + AK E SVKDRI MI DAE+ Sbjct: 95 SPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAER 154 Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 G +KPG+++ IEPTSGNTG+GLA AA +GY+ II MP MS+E+ +L A G E+V T Sbjct: 155 DGTLKPGDTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT 213 Query: 120 DPAKGM----KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDG 175 P + + A + + PN ++L Q+ N +NP HY+TT EI + GK+D Sbjct: 214 -PTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDM 272 Query: 176 FVSGIGTGGTITGAGKYLKEQNANVKLYGVEP-----VESAILSGGKPGPHKIQGIGAGF 230 V+ +GTGGTITG + LKE+ ++ GV+P E L+ + ++++GIG F Sbjct: 273 LVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDF 332 Query: 231 IPSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKL 290 IP+VL+ ++D+ + + +E+ AR L +EGLL G S+G+ A A+K AQ + G+ Sbjct: 333 IPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQE-GQR 391 Query: 291 FVAIFPSFGERYLSTVLFD 309 V I P Y++ L D Sbjct: 392 CVVILPDSVRNYMTKFLSD 410 >5MMS-A nrPDB Length = 408 Score = 217 bits (552), Expect = 7e-57, Method: Compositional matrix adjust. Identities = 123/319 (38%), Positives = 186/319 (58%), Gaps = 14/319 (4%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEK 59 + +I D+ + IG+TP+V +N + + G + AK E SVKDRI MI DAE+ Sbjct: 73 SPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAER 132 Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 G +KPG+++ IEPTSGNTG+GLA AA +GY+ II MP MS+E+ +L A G E+V T Sbjct: 133 DGTLKPGDTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT 191 Query: 120 DPAKGM----KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDG 175 P + + A + + PN ++L Q+ N +NP HY+TT EI + GK+D Sbjct: 192 -PTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDM 250 Query: 176 FVSGIGTGGTITGAGKYLKEQNANVKLYGVEP-----VESAILSGGKPGPHKIQGIGAGF 230 V+ +GTGGTITG + LKE+ ++ GV+P E L+ + ++++GIG F Sbjct: 251 LVASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDF 310 Query: 231 IPSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKL 290 IP+VL+ ++D+ + + +E+ AR L +EGLL G S+G+ A A+K AQ + G+ Sbjct: 311 IPTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQE-GQR 369 Query: 291 FVAIFPSFGERYLSTVLFD 309 V I P Y++ L D Sbjct: 370 CVVILPDSVRNYMTKFLSD 388 >6C2H-A nrPDB Length = 375 Score = 209 bits (533), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 130/324 (40%), Positives = 180/324 (55%), Gaps = 17/324 (5%) Query: 8 DVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP 65 +V +L+GNTPL+ L + A G ++ AKLE+ P S+KDRI SM+ +AE G I P Sbjct: 35 NVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIHP 94 Query: 66 GESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGM 125 S LIEPTSGNTG+GLA A KGY+ IIT+P MS E+ +L A G E++ T A Sbjct: 95 SRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAAW 154 Query: 126 ---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWK-----GTGGKIDGFV 177 + I A+++ + P +L Q+ N NP+ HY TG EI + + V Sbjct: 155 DSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAVV 214 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAI-----LSGGKPGPHKIQGIGAGFIP 232 +G GTGGTI+G KYLKEQN +++ G +P S + L+ +K++GIG F+P Sbjct: 215 AGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFVP 274 Query: 233 SVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQ-RPE-NAGKL 290 VL+ LID + S ARQL EG+LVG SSG+A A +K + PE + Sbjct: 275 QVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDDV 334 Query: 291 FVAIFPSFGERYLSTVLFDATRKE 314 VAIFP YL+ + D K+ Sbjct: 335 IVAIFPDSIRSYLTKFVDDEWLKK 358 >5OHX-A nrPDB Length = 504 Score = 209 bits (532), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 137/312 (43%), Positives = 193/312 (61%), Gaps = 13/312 (4%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKK 60 ++I D+ IG TPL+ LNN+ + G + AK E + P SVKDRI + MI DAE K Sbjct: 33 TKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDK 92 Query: 61 GLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 GL+KPG +IEPTSGNTG+GLA AA +GYK II MP MS E+ L A G +++ T Sbjct: 93 GLLKPG-CTIIEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTP 151 Query: 121 PAKGM---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 + I+ A+++ + PN +L Q+ NP NP HY+ T EIWK GKID V Sbjct: 152 TEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLV 211 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEP----VESAILSGGKPGPHKIQGIGAGFIPS 233 +G GTGGTI+G G+ LKE + N+K+ V+P ++ + S + G ++++GIG FIP+ Sbjct: 212 AGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDSQNEVGFYEVEGIGYDFIPT 271 Query: 234 VLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQR-PENAGKLFV 292 VL+ ++ID+ ++ +ES++ AR L +EGLL G SSGAA AA+K+A+ PE K V Sbjct: 272 VLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEE--KRMV 329 Query: 293 AIFPSFGERYLS 304 I P YL+ Sbjct: 330 IILPDGIRNYLT 341 >3X43-A nrPDB Length = 332 Score = 206 bits (523), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 130/303 (42%), Positives = 189/303 (62%), Gaps = 7/303 (2%) Query: 9 VTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGES 68 + + IG TP+V L +A V K+E P SVKDR+ S++ DAE KGL+KPG++ Sbjct: 7 ILDTIGRTPIVRLQRMAPEHTS-VYVKVESFNPGGSVKDRLALSVVLDAEAKGLLKPGDT 65 Query: 69 VLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGA 128 + +E TSGN G+ LA AAA+GY+ + M + S ERR ++ A+G +LVL G KG Sbjct: 66 I-VECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHLGSKGG 124 Query: 129 IAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGK-IDGFVSGIGTGGTIT 187 A+E LA+ + +QF+NPANP H ETT EI GK +D FV+G GT GT+T Sbjct: 125 NLIADE-LAEKYGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGTTGTLT 183 Query: 188 GAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVS 247 G G+ L+ V++ +EP +A+L+ G+ PH+IQG+ F+P VL+ +ID++V + Sbjct: 184 GVGQMLRVARPEVRVVALEPSNAAMLARGEWSPHQIQGLAPNFVPGVLDRSVIDDLVTMD 243 Query: 248 SDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQR-PENAGKLFVAIFPSFGERYLSTV 306 + D +R+LA +EG+ GIS+GA A A+ +A+ PE G + +A+ P GERYLST Sbjct: 244 EVTARDTSRRLAAEEGIFAGISAGATVATALSIAEHAPE--GTVLLAMLPDTGERYLSTF 301 Query: 307 LFD 309 LFD Sbjct: 302 LFD 304 >5B1I-A nrPDB Length = 311 Score = 201 bits (510), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 123/303 (40%), Positives = 178/303 (58%), Gaps = 6/303 (1%) Query: 7 KDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 66 + V ELIG+TPL+ L + + AKLEM P S+ DR+G +I D ++G + Sbjct: 4 QHVQELIGHTPLMALP-IEVPNHSHIYAKLEMFNPGGSIADRLGAYLIEDGLQRGRVN-A 61 Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMK 126 ++ +IEPT+GNTG+GLA A + I+ +P S E+++++ A G E+V T +G+K Sbjct: 62 KTTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEGIK 121 Query: 127 GAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTI 186 GAI KAE + A N Y+ QF+NPANP +Y T PEI I FV+G G+GGT Sbjct: 122 GAIRKAEALAATISNSYVPMQFKNPANPAAYYHTLAPEILADMPAPITAFVAGAGSGGTF 181 Query: 187 TGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQV 246 G YL+ Q++ K VEP E +IL+GG H+ +GIG FIP + ID+ + + Sbjct: 182 AGVAAYLQAQDSATKAVVVEP-EGSILNGGPAHAHRTEGIGVEFIPPFFDQVRIDQTLTI 240 Query: 247 SSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQR-PENAGKLFVAIFPSFGERYLST 305 + +++ R LA GLL+G SSGAA AA+++LA P N+ V IFP ERYLS Sbjct: 241 ADNDAFAQVRHLARDHGLLIGSSSGAALAASLQLATNLPANSH--IVTIFPDSSERYLSQ 298 Query: 306 VLF 308 ++ Sbjct: 299 KIY 301 >3PC3-A nrPDB Length = 527 Score = 192 bits (488), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 124/318 (38%), Positives = 183/318 (57%), Gaps = 14/318 (4%) Query: 3 SRIAKDVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKK 60 +I ++ E+IG TPLV LNN+ ++G + AK E + P SVKDRIG+ M+ DAE++ Sbjct: 48 QQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQ 107 Query: 61 GLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 GL+KPG ++ IEPTSGNTG+GLA A KGYK II MP MS E+ L G +++ T Sbjct: 108 GLLKPGYTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRT- 165 Query: 121 PAKGM----KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGF 176 P + +G I A+++ +TPN +L Q+ N NP HY+ T EI K+D Sbjct: 166 PTEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMI 225 Query: 177 VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVES-----AILSGGKPGPHKIQGIGAGFI 231 V GT GTI+G G+ +KEQ + ++ GV+P S A L+ ++++GIG F Sbjct: 226 VVSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFP 285 Query: 232 PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLF 291 P+V + ++D ++ + M+R+L +EGLL G SSG A AA++ A R G+ Sbjct: 286 PTVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA-RKLKKGQRC 344 Query: 292 VAIFPSFGERYLSTVLFD 309 V I P Y++ + D Sbjct: 345 VVILPDGIRNYMTKFVSD 362 >5JJC-A nrPDB Length = 342 Score = 180 bits (457), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 116/314 (36%), Positives = 171/314 (54%), Gaps = 19/314 (6%) Query: 9 VTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 66 V + IGNTPL+ L+ +E GC + K E + P SVKDR +I DAEK+GL++PG Sbjct: 5 VLDTIGNTPLIRLSKASELTGC--DIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLRPG 62 Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELV------LTD 120 V++E T+GNTG+GL A A GY+ I +P + S E++ L G EL+ + Sbjct: 63 -GVIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPYRN 121 Query: 121 PAKGMKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVSG 179 P ++ + AE++ PNG + QF+N N + H ETT EIW+ T +IDGFV+ Sbjct: 122 PNNAVRLSGRLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFVAA 181 Query: 180 IGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHK------IQGIGAGFIPS 233 +G+GGT+ G LKE+N N+K+ +P +A+ + G K +GIG G I + Sbjct: 182 VGSGGTLAGTAIGLKERNHNIKIALADPHGAALHAFYTTGELKAEGDSITEGIGQGRITA 241 Query: 234 VLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVA 293 L D Q+ E++D+ L +EGL +G SSG A AI+LA + G V Sbjct: 242 NLEGFTPDFSYQIPDAEALDILFALVEEEGLCLGGSSGINIAGAIRLA-KDLGPGHTIVT 300 Query: 294 IFPSFGERYLSTVL 307 + +G RY S + Sbjct: 301 VLCDYGNRYQSKLF 314 >5B55-A nrPDB Length = 340 Score = 166 bits (421), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 123/319 (38%), Positives = 176/319 (55%), Gaps = 11/319 (3%) Query: 7 KDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 66 K + L+G TP++ L +G R+ K E S+KDR+ F + A +K IK G Sbjct: 11 KYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNEIKKG 70 Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG-M 125 + +E TSGNTG+ + A G+ +II MP MS ER+ ++ +FG +++L +G Sbjct: 71 API-VEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRKEGGF 129 Query: 126 KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEI---WKGTGGKIDGFVSGIGT 182 G+I K +E P+ Y+ QF N N + HY G EI K IDGFV+G+GT Sbjct: 130 LGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVAGVGT 189 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGG-KPGPHKIQGIGAGFIPSVLNVDLID 241 GGT+ G GK +KE +N K+ +EP+ S LS G K H+I+GI FIP ++ +D +D Sbjct: 190 GGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKLDKLD 249 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 VV V ++I MA++LA K GL VGISSGA A+ L Q + V +FP ++ Sbjct: 250 NVVSVDDGDAIVMAQKLA-KCGLGVGISSGANFIGALML-QNKLGKDSVIVTVFPDDNKK 307 Query: 302 YLSTVLFDATRKEAEAMTF 320 YLST D R+E F Sbjct: 308 YLST---DLMREEKVKEDF 323 >5I7O-A nrPDB Length = 326 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 103/269 (38%), Positives = 154/269 (57%), Gaps = 16/269 (5%) Query: 11 ELIGNTPLVYLNNVA-------EGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLI 63 + +GNTPLV L ++ +G R+ AKLE P S+KDR MI AE GL+ Sbjct: 12 QALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAEADGLL 71 Query: 64 KPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 123 +PG ++L EPTSGNTG+ LA A KGY+LI MP + S ERR +L +G +++ + Sbjct: 72 RPGATIL-EPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIFSAAEG 130 Query: 124 GMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 183 G A+A A+E+ A P+ ML Q+ NPAN HY TGPE+ +I FV+G+GT Sbjct: 131 GSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADL-PEITHFVAGLGTT 189 Query: 184 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 GT+ G G++L+E ANVK+ EP G + ++ + GF+P + + +++ Sbjct: 190 GTLMGTGRFLREHVANVKIVAAEPRYGE-------GVYALRNMDEGFVPELYDPEILTAR 242 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGA 272 V + +++ R+L EG+ GIS+GA Sbjct: 243 YSVGAVDAVRRTRELVHTEGIFAGISTGA 271 >5D84-A nrPDB Length = 326 Score = 148 bits (374), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 106/301 (35%), Positives = 155/301 (51%), Gaps = 9/301 (2%) Query: 13 IGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIE 72 +G TP+V L+ + V AKLE M P S+KDR +I K GLI + LIE Sbjct: 16 VGQTPMVQLHQLFPK--HEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHGLITEN-THLIE 72 Query: 73 PTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFG--VELVLTDPAKG--MKGA 128 TSGN G+ LA A KG KL + +S I+ ++G VE+V A G + Sbjct: 73 STSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEEPDAHGGYLMTR 132 Query: 129 IAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITG 188 IAK +E+LA + Y + Q+ N N + HY G EI + ID FV+ + T G+I G Sbjct: 133 IAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQPIDYFVAPVSTTGSIMG 192 Query: 189 AGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSS 248 + +KE + N ++ V+ + +++ G KP ++ GIGA +P +LN I++V+ V Sbjct: 193 MSRKIKEVHPNAQIVAVD-AKGSVIFGDKPINRELPGIGASRVPEILNRSEINQVIHVDD 251 Query: 249 DESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLF 308 +S R+L EG+ G S+G+ AA +L E G V I P G+RYL V Sbjct: 252 YQSALGCRKLIDYEGIFAGGSTGSIIAAIEQLITSIEE-GATIVTILPDRGDRYLDLVYS 310 Query: 309 D 309 D Sbjct: 311 D 311 >3VSD-A nrPDB Length = 389 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 74/285 (25%), Positives = 138/285 (48%), Gaps = 26/285 (9%) Query: 31 RVAAKLEMMEPCS-SVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAK 89 RV KLE P S SV DR +IS ++ ++ G S++ + TS N GV L+ A Sbjct: 111 RVWLKLEWYNPFSLSVADRPAVEIISRLSRR--VEKG-SLVADATSSNFGVALSAVARLY 167 Query: 90 GYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPN-GYM-LQQ 147 GY+ + +P + +++ G + V+ DP + ++ + N G++ + Q Sbjct: 168 GYRARVYLPGAAEEFGKLLPRLLGAQ-VIVDPEA--PSTVHLLPRVMKDSKNEGFVHVNQ 224 Query: 148 FENPANPKIHYETTGPEIW---KGTGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYG 204 F N AN + H T EI+ + G + G +GT G ++ A YL+ + +++ Sbjct: 225 FYNDANFEAHMRGTAREIFVQSRRGGLALRGVAGSLGTSGHMSAAAFYLQSVDPSIRAVL 284 Query: 205 VEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID---EVVQVSSDESIDMARQLALK 261 V+P + + PG +++ +L ++++D + +V+ +E+++ ++A Sbjct: 285 VQPAQGDSI----PGIRRVE-------TGMLWINMLDISYTLAEVTLEEAMEAVVEVARS 333 Query: 262 EGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 +GL++G S GAA A K A + +V + P G +YLS V Sbjct: 334 DGLVIGPSGGAAVKALAKKAAEGDLEPGDYVVVVPDTGFKYLSLV 378 >5X2L-A nrPDB Length = 348 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 62/267 (23%), Positives = 109/267 (40%), Gaps = 40/267 (14%) Query: 35 KLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLI 94 K E+ + S K R + + L + ++V+ +SGN G L + A +G Sbjct: 45 KCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTH-SSGNHGQALTYAAKLEGIPAY 103 Query: 95 ITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANP 154 I +P + +++ + A+G +V +P+ + +AK + + G M+ + PA Sbjct: 104 IVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKR---VTEETEGIMVHPNQEPA-- 158 Query: 155 KIHYETTGPEIWKGTGG----------KIDGFVSGIGTGGTITGAGKYLKEQNANVKLYG 204 + G G +D V +G GG + G +K +VK+Y Sbjct: 159 ----------VIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKALKPSVKVYA 208 Query: 205 VEPVESAILSGGK------PGPHKIQGIGAGFIPSV-LNV-----DLIDEVVQVSSDESI 252 EP + K P + + I G S+ LN DL+D++ V+ DE I Sbjct: 209 AEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTVTEDE-I 267 Query: 253 DMARQLALKE-GLLVGISSGAAAAAAI 278 A QL + LL+ ++G AA + Sbjct: 268 KCATQLVWERMKLLIEPTAGVGVAAVL 294 >5KZM-B nrPDB Length = 396 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 50/180 (27%), Positives = 74/180 (41%), Gaps = 34/180 (18%) Query: 159 ETTGPEIWKGTGGKIDGFVSGIGTGGTITGA-GKYLKEQNANVKLYGVEPVESAILSG-- 215 E T ++ G D ++ +G G G ++ E+N VKL GVEP I +G Sbjct: 209 EETKQQMLAKEGRLPDAVIACVGGGSNAIGMFADFIDEKN--VKLIGVEPAGKGIETGEH 266 Query: 216 GKPGPHKIQGIGAGF-IPSVLNVD-LIDEVVQVSS------------------------- 248 G P H GI G P + N D I+E +S+ Sbjct: 267 GAPLKHGKTGIFFGMKAPLMQNSDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAKYASA 326 Query: 249 --DESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 DE++D + L KEG++ + S A A A+KLA N +L V G++ + TV Sbjct: 327 TDDEALDAFKLLCKKEGIIPALESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFTV 386 >3L6C-A nrPDB Length = 339 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 52/273 (19%) Query: 35 KLEMMEPCSSVKDRIGFSMISDAEKKGLI------KPGESVLIEPTSGNTGVGLAFTAAA 88 K E+ + S K R + I +GLI KP ++ +SGN G L + A Sbjct: 45 KCELFQKTGSFKIRGALNAI-----RGLIPDTLEGKP--KAVVTHSSGNHGQALTYAAKL 97 Query: 89 KGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQF 148 +G I +P + +++ + A+G +V ++P+ + + A+ I+ +T G ++ Sbjct: 98 EGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENV--AQRIIQET-EGILVHPN 154 Query: 149 ENPANPKIHYETTGPEIWKGTGG----------KIDGFVSGIGTGGTITGAGKYLKEQNA 198 + PA + G G +D V +G GG + G +K Sbjct: 155 QEPA------------VIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTLKP 202 Query: 199 NVKLYGVEPVESAILSGGK------PGPHKIQGIGAGFIPSV-LNV-----DLIDEVVQV 246 +VK+Y EP + K P H + I G S+ LN DL+D+V V Sbjct: 203 SVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPIIRDLVDDVFTV 262 Query: 247 SSDESIDMARQLALKE-GLLVGISSGAAAAAAI 278 + DE I A QL + LL+ ++G AA + Sbjct: 263 TEDE-IKYATQLVWERMKLLIEPTAGVGLAAVL 294 >1TDJ-A nrPDB Length = 514 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 11/138 (7%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESV-LIEPT 74 TPL + ++ + K E +P S K R ++M++ GL + ++ +I + Sbjct: 32 TPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMA-----GLTEEQKAHGVITAS 86 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 134 +GN G+AF++A G K +I MP + + + + FG E++L G AKA+ Sbjct: 87 AGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLL----HGANFDEAKAKA 142 Query: 135 ILAKTPNGY-MLQQFENP 151 I G+ + F++P Sbjct: 143 IELSQQQGFTWVPPFDHP 160 >3IAU-A nrPDB Length = 366 Score = 37.7 bits (86), Expect = 0.007, Method: Compositional matrix adjust. Identities = 60/241 (24%), Positives = 101/241 (41%), Gaps = 18/241 (7%) Query: 35 KLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLI 94 K E + S K R ++M+S+ ++ L K +I ++GN G+A Sbjct: 80 KREDKQRVFSFKLRGAYNMMSNLSREELDKG----VITASAGNHAQGVALAGQRLNCVAK 135 Query: 95 ITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANP 154 I MP + + + A G ++VL K A A E+ K Y + F++P Sbjct: 136 IVMPTTTPQIKIDAVRALGGDVVLY--GKTFDEAQTHALELSEKDGLKY-IPPFDDPGVI 192 Query: 155 KIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILS 214 K T G EI + I +G GG I G + K+ N K+ GVEP +A ++ Sbjct: 193 KGQ-GTIGTEINRQLK-DIHAVFIPVGGGGLIAGVATFFKQIAPNTKIIGVEPYGAASMT 250 Query: 215 GGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAA 274 H+++ + NVD + V V+ A+ L +G+++ + G +A Sbjct: 251 LSLHEGHRVK---------LSNVDTFADGVAVALVGEYTFAKCQELIDGMVLVANDGISA 301 Query: 275 A 275 A Sbjct: 302 A 302 >5YGR-A nrPDB Length = 404 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 47 DRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERR 106 + + F+ ++ E K IK + V + T GN G G+A+ A G K ++ MP S R Sbjct: 99 NSLSFAALNTPEIKEKIK--DCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRA 156 Query: 107 IILLAFGVELVLTD 120 + G E +TD Sbjct: 157 ENIRHHGAECTITD 170 >4D9G-A nrPDB Length = 398 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%) Query: 74 TSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 T GN G G+A+ A G +I MP + ER +L G E ++TD Sbjct: 119 TDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVTD 165 >6NMX-A nrPDB Length = 354 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 15/187 (8%) Query: 14 GNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEP 73 GNTPL++L ++E + K E + P S KDR ++ A+++ G ++ Sbjct: 29 GNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEE-----GNDTIMCA 83 Query: 74 TSGNTGVGLAFTAAAKGYKLIITMP-ASMSTERRIILLAFGVELVLTDPAKGMKGAIAKA 132 ++GNT A AA K I+ +P ++ + + +G E++ D A+ Sbjct: 84 STGNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAID--GNFDDALKIV 141 Query: 133 EEILAKTPNGYMLQQFENPANP-KIHYETTGP-EIWKGTGGKIDGFVSGIGTGGTITGAG 190 I K+P + N NP ++ + T E+ + G D +G G I+ Sbjct: 142 RSICEKSPIALV-----NSVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYW 196 Query: 191 KYLKEQN 197 K KE + Sbjct: 197 KGFKEYH 203 >2ZSJ-A nrPDB Length = 352 Score = 35.4 bits (80), Expect = 0.031, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 7/72 (9%) Query: 9 VTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 66 VT GNTPL+ +N+A G G++ K E + P S KDR IS A ++ G Sbjct: 24 VTLYEGNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAISKA-----VEAG 78 Query: 67 ESVLIEPTSGNT 78 + +I ++GNT Sbjct: 79 KRAVICASTGNT 90 >1VE5-A nrPDB Length = 311 Score = 35.4 bits (80), Expect = 0.033, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 11/86 (12%) Query: 70 LIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAI 129 L+ +SGN G+A+ A G K ++ MP S ++ A+G E+V +G Sbjct: 68 LLAVSSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVV-------DRGVT 120 Query: 130 AKAEEILAKT---PNGY-MLQQFENP 151 AK E +A+ GY ++ F++P Sbjct: 121 AKNREEVARALQEETGYALIHPFDDP 146 >5YBW-A nrPDB Length = 329 Score = 34.7 bits (78), Expect = 0.058, Method: Compositional matrix adjust. Identities = 53/248 (21%), Positives = 103/248 (41%), Gaps = 25/248 (10%) Query: 35 KLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLI 94 K E ++ S K R + I A ++ +P + ++ +SGN G LA+ + G K Sbjct: 48 KAENLQKTGSFKARGALNAILCALER---EPSLAGVVTHSSGNHGQALAWASKRAGVKCC 104 Query: 95 ITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANP 154 + +P + + + +G E+V +P + E LAK+ GY + + Sbjct: 105 VVVPKTAPQVKFDAMENYGAEVVKCEPNPTSRKETC---EGLAKS-RGYKYISSSDDYDV 160 Query: 155 KIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEP----VES 210 T E+ + +D + + GG +G Y K +++K++ VEP +E Sbjct: 161 IAGQGTIALELLQQQPD-LDAILVSVSAGGMASGICVYTKNTKSDLKVFLVEPEGKMLEE 219 Query: 211 AILSGGK--PGPHK----------IQGIGAGFIPSVLNVDLIDEVVQVSSDESIDMARQL 258 I + P P + +Q G P +L + EV+ V++D ++ R + Sbjct: 220 CISKRERLWPNPPQFLDTIADGIILQQCGNKTWPIILELPE-KEVITVNNDNIVEAMRFV 278 Query: 259 ALKEGLLV 266 + L++ Sbjct: 279 FARMKLVI 286 >5EY5-B nrPDB Length = 399 Score = 34.3 bits (77), Expect = 0.079, Method: Compositional matrix adjust. Identities = 83/347 (23%), Positives = 142/347 (40%), Gaps = 72/347 (20%) Query: 16 TPLVYLNNVAEGCVG-RVAAKLEMMEP--CSSVKDRIGFSMISDAEKKGLIKPGESVLIE 72 TPL + N+ + G ++ K E + + + +G ++++ K + V+ E Sbjct: 51 TPLYFAENLTKDLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGK------KRVIAE 104 Query: 73 PTSGNTGVGLAFTAAAKGYKLIITMPASMSTER------RIILLAFGVELVLTDPAKGMK 126 +G GV A AA G + ++ M A ER R+ LL V V T ++ +K Sbjct: 105 TGAGQHGVATATVAAMFGLECVVYMGAE-DIERQALNVFRMKLLGAKVRPV-TSGSRTLK 162 Query: 127 GAIAKAEE---------------ILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGG 171 AI +A ++ P M++ F++ E +I + G Sbjct: 163 DAINEAMRDWVTNVEDTFYIIGSVVGPHPYPMMVRDFQSVIG-----EEARQQILEKEGR 217 Query: 172 KIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPV--------ESAILSGGKPGP-H- 221 D V+ +G G G + + +V+L GVE +A LS G+PG H Sbjct: 218 LPDAIVACVGGGSNAMGIFHPFID-DESVRLIGVEAAGKGIETGKHAATLSAGRPGVLHG 276 Query: 222 --------------KIQGIGAGF-IPSV--LNVDLID----EVVQVSSDESIDMARQLAL 260 + I AG P V + L D E V V+ DE+++ + L+ Sbjct: 277 AMTYLLQDEDGQIIEAHSISAGLDYPGVGPEHAYLKDTGRAEYVSVTDDEALEAFQLLSR 336 Query: 261 KEGLLVGISSGAAAAAAIKLAQRPE-NAGKLFVAIFPSFGERYLSTV 306 EG++ + S A A A+KLA PE + ++ V G++ ++TV Sbjct: 337 TEGIIPALESSHAVAYAMKLA--PELSKDQIIVVNLSGRGDKDVNTV 381 >2GN1-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.15, Method: Compositional matrix adjust. Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 13/133 (9%) Query: 22 NNVAEGCVGRVAAKLEMMEPCSSVKDRIGF---SMISDAEKKGLIKPGESVLIEPTSGNT 78 N +E C G + K E M+ S K R F S +++AEK+ + + ++GN Sbjct: 47 NYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKGV-------VACSAGNH 99 Query: 79 GVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAK 138 G++ + A G + MP + + E+VL IAK EI+ + Sbjct: 100 AQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVL--HGDNFNDTIAKVSEIV-E 156 Query: 139 TPNGYMLQQFENP 151 T + +++P Sbjct: 157 TEGRIFIPPYDDP 169 >2D1F-A nrPDB Length = 360 Score = 33.1 bits (74), Expect = 0.17, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 7/91 (7%) Query: 9 VTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSM-ISDAEKKGLIKPGE 67 VT L G TPL+ N+++ + K+E + P S KDR G +M ++DA + G+ Sbjct: 32 VTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDR-GMTMAVTDA-----LAHGQ 85 Query: 68 SVLIEPTSGNTGVGLAFTAAAKGYKLIITMP 98 ++ ++GNT A AA G + +P Sbjct: 86 RAVLCASTGNTSASAAAYAARAGITCAVLIP 116 >1CX9-B nrPDB Length = 397 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 63/290 (21%), Positives = 110/290 (37%), Gaps = 60/290 (20%) Query: 69 VLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERR----IILLAFGVELV------- 117 ++ E +G GV A +A G K I M A ER+ + G E++ Sbjct: 106 IIAETGAGQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVIPVHSGSA 164 Query: 118 -----LTDPAKGMKGAIAKAEEIL--AKTPNGY--MLQQFENPANPKIHYETTGPEIWKG 168 + + G+ A +L A P+ Y ++++F+ ++ E T +I Sbjct: 165 TLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQ-----RMIGEETKAQILDK 219 Query: 169 TGGKIDGFVSGIGTGGTITGA-GKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIG 227 G D ++ +G G G ++ + +V L GVEP I +G P K +G Sbjct: 220 EGRLPDAVIACVGGGSNAIGMFADFIN--DTSVGLIGVEPGGHGIETGEHGAPLKHGRVG 277 Query: 228 AGF-------------------------IPSV------LNVDLIDEVVQVSSDESIDMAR 256 F PSV LN + V ++ DE+++ + Sbjct: 278 IYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFK 337 Query: 257 QLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 L EG++ + S A A A+K+ + +L V G++ + TV Sbjct: 338 TLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTV 387 >3R0X-A nrPDB Length = 448 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 33/143 (23%), Positives = 62/143 (43%), Gaps = 24/143 (16%) Query: 44 SVKDRIG-FSMISDAEK----KGLIKPGE--SVLIEP--------------TSGNTGVGL 82 S+K R G + +++ AEK GL+ + SVL+ P ++GN G+ + Sbjct: 114 SIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSI 173 Query: 83 AFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNG 142 +A G+K+ + M A ++ L + GV +V + G+ A+ + + PN Sbjct: 174 GIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGV--AVEQGRKAAQSDPNC 231 Query: 143 YMLQQFENPANPKIHYETTGPEI 165 + + EN + Y G + Sbjct: 232 FFIDD-ENSRTLFLGYAVAGQRL 253 >1G3N-B nrPDB Length = 168 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 7/59 (11%) Query: 32 VAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVL-------IEPTSGNTGVGLA 83 +A +L + +KDR GF++I DA + G + +++L IE GN + LA Sbjct: 52 IARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 >1YB5-A nrPDB Length = 351 Score = 30.8 bits (68), Expect = 0.87, Method: Compositional matrix adjust. Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 2/47 (4%) Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIIL 109 +K GESVL+ SG GVGLA A+ Y L I A ++I+L Sbjct: 168 VKAGESVLVHGASG--GVGLAACQIARAYGLKILGTAGTEEGQKIVL 212 >1J71-A nrPDB Length = 334 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 43 SSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGV-GLAFTAAAKGYKLIITMPASM 101 S KD +GF IS IK + + TS + G+ G+ FTA GY L +P ++ Sbjct: 93 SFYKDTVGFGGIS-------IKNQQFADVTTTSVDQGIMGIGFTADEAGYNLYDNVPVTL 145 Query: 102 STERRIILLAFGVELVLTDPAKG 124 + I A+ + L D + G Sbjct: 146 KKQGIINKNAYSLYLNSEDASTG 168 >4NEG-A nrPDB Length = 400 Score = 29.3 bits (64), Expect = 2.6, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 27/44 (61%), Gaps = 1/44 (2%) Query: 246 VSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLA-QRPENAG 288 ++ DE+++ + L KEG++ + S A A A+KLA Q E+ G Sbjct: 334 ITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEG 377 >3SS9-X nrPDB Length = 442 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Query: 74 TSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAE 133 ++GN G+ + +A G+K+ + M A ++ L + GV +V + G+ A+ + Sbjct: 167 STGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV--AVEEGR 224 Query: 134 EILAKTPNGYMLQQFENPANPKIHYETTGPEI 165 + PN + + EN + Y G + Sbjct: 225 KAAQSDPNCFFIDD-ENSRTLFLGYSVAGQRL 255 >5OVJ-A nrPDB Length = 256 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 9/58 (15%) Query: 67 ESVLIEPTSGNTGVGLAFTA--AAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 SVL+ T GN G+GLA AA G+K+ +T S + + FGV+ +TD A Sbjct: 25 RSVLV--TGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDD-----LFGVQCDVTDSA 75 >5OVL-A nrPDB Length = 300 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 9/58 (15%) Query: 67 ESVLIEPTSGNTGVGLAFTA--AAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 SVL+ T GN G+GLA AA G+K+ +T S + + FGV+ +TD A Sbjct: 69 RSVLV--TGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDD-----LFGVQCDVTDSA 119 >3HOX-E nrPDB Length = 215 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/70 (21%), Positives = 36/70 (51%), Gaps = 8/70 (11%) Query: 228 AGFIPSVLNVDLIDEVVQVSSDESIDMARQLALKEGLL--------VGISSGAAAAAAIK 279 A + ++ + +L+ + +++SSDE ++ ++ LKE L V + G +K Sbjct: 138 AALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVK 197 Query: 280 LAQRPENAGK 289 + ++ E +G+ Sbjct: 198 IIRKSETSGR 207 >6AMI-A nrPDB Length = 396 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 25/41 (60%) Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQ 282 E V V+ +E++ +L+ EG++ + S A A A+KLA+ Sbjct: 318 EYVAVTDEEALKAFHELSRTEGIIPALESAHAVAYAMKLAK 358 >1UZM-A nrPDB Length = 247 Score = 27.7 bits (60), Expect = 6.3, Method: Compositional matrix adjust. Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 9/56 (16%) Query: 67 ESVLIEPTSGNTGVGLAFTA--AAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 SVL+ T GN G+GLA AA G+K+ +T S + + FGVE+ +TD Sbjct: 16 RSVLV--TGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPKG-----LFGVEVDVTD 64 >1UIN-A nrPDB Length = 351 Score = 27.7 bits (60), Expect = 7.1, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 43/93 (46%), Gaps = 7/93 (7%) Query: 9 VTELIGNTPLVYLNNVAEGCVG--RVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 66 ++ L G+TPL+ L E R+ AK E + P S KDR +S A ++ G Sbjct: 22 ISLLEGSTPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKA-----VEGG 76 Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPA 99 + ++GNT A AA G I+ +PA Sbjct: 77 AQAVACASTGNTAASAAAYAARAGILAIVVLPA 109 >3RLI-A nrPDB Length = 270 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 13/61 (21%) Query: 176 FVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAI--------LSGGKPGPHKIQGIG 227 FV+G+ GGT+T YL E + ++ G+ P+ +A+ ++GG P + IG Sbjct: 112 FVTGLSMGGTLT---LYLAEHHPDIC--GIVPINAAVDIPAIAAGMTGGGELPRYLDSIG 166 Query: 228 A 228 + Sbjct: 167 S 167 >3TK1-A nrPDB Length = 330 Score = 27.3 bits (59), Expect = 8.3, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 177 VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGG 216 V G+G +I G +L EQ V + V+P S++ SGG Sbjct: 64 VPGVGKSTSIEALGMHLIEQGHRVAVLAVDP--SSVRSGG 101 >5C3U-A nrPDB Length = 366 Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust. Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 9/102 (8%) Query: 8 DVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDR-IGFSMISDAEKKGLIKPG 66 D+ L TPL++ N+ + V K+E ++P SVK R IG + + G Sbjct: 14 DLQSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQTR-----G 68 Query: 67 ESVLIEPTSG-NTGVGLAFTAAAKGYKLIITMPASMSTERRI 107 ++ SG NT + +++ A G + II +P +T RI Sbjct: 69 TNIQFVCGSGPNTVLAVSYCARQLGVEAIIVVPK--ATNERI 108 >5GT5-A nrPDB Length = 446 Score = 27.3 bits (59), Expect = 9.9, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 81 GLAFTAAAKGYKLIITMPASMSTERRIILL 110 G+A A+KGYK IT ++STE +L+ Sbjct: 307 GMAAAIASKGYKFGITSNGAISTESNAVLV 336 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2ISQ-A nrPDB 481 e-136 4AEC-A nrPDB 446 e-126 3VBE-A nrPDB 439 e-124 2Q3D-A nrPDB 430 e-121 4LMA-A nrPDB 428 e-120 4I1Y-A nrPDB 419 e-118 5XA2-A nrPDB 417 e-117 4LMB-A nrPDB 415 e-116 4COO-A nrPDB 413 e-116 1M54-A nrPDB 411 e-115 5MMS-A nrPDB 410 e-115 3T4P-A nrPDB 396 e-111 2BHS-A nrPDB 390 e-109 3FCA-A nrPDB 389 e-109 5OHX-A nrPDB 388 e-108 2JC3-A nrPDB 388 e-108 5XW3-A nrPDB 387 e-108 5J5V-A nrPDB 386 e-107 4OFX-A nrPDB 385 e-107 2EFY-A nrPDB 383 e-107 3PC3-A nrPDB 382 e-107 6C2H-A nrPDB 381 e-106 2EGU-A nrPDB 379 e-106 2PQM-A nrPDB 373 e-104 5XEM-A nrPDB 363 e-101 6AHI-A nrPDB 363 e-101 5XCN-X nrPDB 350 5e-97 3X43-A nrPDB 345 1e-95 5D84-A nrPDB 342 1e-94 5JJC-A nrPDB 341 2e-94 5B1I-A nrPDB 339 1e-93 5B55-A nrPDB 321 2e-88 5I7O-A nrPDB 315 2e-86 3VSD-A nrPDB 226 1e-59 5X2L-A nrPDB 224 4e-59 3L6C-A nrPDB 195 2e-50 5KZM-B nrPDB 153 1e-37 Sequences not found previously or not previously below threshold: 1CX9-B nrPDB 132 2e-31 5YBW-A nrPDB 116 1e-26 5EY5-B nrPDB 114 5e-26 5OCW-B nrPDB 108 3e-24 6AMI-A nrPDB 106 1e-23 5CVC-A nrPDB 106 1e-23 1V71-A nrPDB 105 2e-23 6NMX-A nrPDB 105 3e-23 1TDJ-A nrPDB 102 2e-22 3IAU-A nrPDB 100 1e-21 2GN1-A nrPDB 100 2e-21 5KIN-B nrPDB 99 3e-21 2D1F-A nrPDB 97 2e-20 1VE5-A nrPDB 95 3e-20 1PWH-A nrPDB 95 4e-20 6HUL-B nrPDB 90 2e-18 1UIN-A nrPDB 89 3e-18 4NEG-A nrPDB 88 5e-18 2ZSJ-A nrPDB 88 6e-18 1X1Q-A nrPDB 86 2e-17 5C3U-A nrPDB 80 2e-15 4H27-A nrPDB 75 4e-14 6EQN-B nrPDB 72 2e-13 5YGR-A nrPDB 71 6e-13 1J0B-A nrPDB 66 3e-11 3R0X-A nrPDB 65 4e-11 4D9F-A nrPDB 62 3e-10 3SS9-X nrPDB 61 4e-10 2RKB-A nrPDB 59 3e-09 4D9G-A nrPDB 59 3e-09 1RQX-A nrPDB 56 3e-08 1E5X-A nrPDB 50 2e-06 1J0D-A nrPDB 43 1e-04 2VCY-A nrPDB 43 1e-04 5K1S-A nrPDB 39 0.002 4RVS-A nrPDB 38 0.007 3IP1-A nrPDB 35 0.039 4J6F-A nrPDB 34 0.069 1VB3-A nrPDB 33 0.25 2UUQ-A nrPDB 32 0.42 4EI8-A nrPDB 31 0.54 3FFK-A nrPDB 31 0.56 3FFN-A nrPDB 31 0.64 4WAD-A nrPDB 31 0.68 2Y4O-A nrPDB 31 0.90 1UUF-A nrPDB 31 0.95 3SKY-A nrPDB 31 0.96 3QWB-A nrPDB 31 0.97 3BKX-A nrPDB 31 1.0 1YB5-A nrPDB 30 1.3 5W8S-A nrPDB 30 1.7 4TLZ-A nrPDB 30 1.7 3GFB-A nrPDB 30 1.7 3NAV-A nrPDB 30 1.8 3RLI-A nrPDB 29 2.2 3KW3-A nrPDB 29 2.2 3CJR-A nrPDB 29 2.6 4V75-AD nrPDB 29 2.7 4ZGV-A nrPDB 29 3.0 3SLK-A nrPDB 29 3.3 5VJ1-D nrPDB 29 3.6 2FZ4-A nrPDB 28 5.2 1PFK-A nrPDB 28 5.5 2E18-A nrPDB 28 6.0 2FWR-A nrPDB 28 6.3 >2ISQ-A nrPDB Length = 320 Score = 481 bits (1238), Expect = e-136, Method: Composition-based stats. Identities = 320/320 (100%), Positives = 320/320 (100%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL Sbjct: 1 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 60 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA Sbjct: 61 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 120 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT Sbjct: 121 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 180 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 242 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE Sbjct: 181 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 240 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY Sbjct: 241 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 300 Query: 303 LSTVLFDATRKEAEAMTFEA 322 LSTVLFDATRKEAEAMTFEA Sbjct: 301 LSTVLFDATRKEAEAMTFEA 320 >4AEC-A nrPDB Length = 430 Score = 446 bits (1147), Expect = e-126, Method: Composition-based stats. Identities = 226/318 (71%), Positives = 274/318 (86%) Query: 4 RIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLI 63 IA +V++LIG TP+VYLN++A+GCV +AAKLE+MEPC SVKDRIG+SM++DAE+KG I Sbjct: 112 NIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFI 171 Query: 64 KPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 123 PG+SVL+EPTSGNTG+GLAF AA++GY+LI+TMPASMS ERR++L AFG ELVLTDPAK Sbjct: 172 SPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAK 231 Query: 124 GMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 183 GM GA+ KAEEIL TP+ YMLQQF+NPANPKIHYETTGPEIW T GK+D FV+GIGTG Sbjct: 232 GMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTG 291 Query: 184 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 GTITG G+++KE+N ++ GVEP ES ILSGGKPGPHKIQGIGAGFIP L+ ++DEV Sbjct: 292 GTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEV 351 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 + +SS+E+I+ A+QLALKEGL+VGISSGAAAAAAIK+A+RPENAGKL +FPSFGERYL Sbjct: 352 IAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYL 411 Query: 304 STVLFDATRKEAEAMTFE 321 ST LF + R+E E M E Sbjct: 412 STPLFQSIREEVEKMQPE 429 >3VBE-A nrPDB Length = 344 Score = 439 bits (1130), Expect = e-124, Method: Composition-based stats. Identities = 195/321 (60%), Positives = 254/321 (79%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 ++ I K V++LIG TPLVYLN V EGC VA K EMM+P +S+KDR ++MI+DAE+K Sbjct: 22 STNIKKHVSQLIGRTPLVYLNKVTEGCGAYVAVKQEMMQPTASIKDRPAYAMITDAEEKN 81 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 LI PG++ LIEPTSGN G+ +AF AA KGYK+++TMP+ S ERR+ + AFG EL+LTDP Sbjct: 82 LITPGKTTLIEPTSGNMGISMAFMAAMKGYKMVLTMPSYTSLERRVTMRAFGAELILTDP 141 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 AKGM G + KA E+L TPN +MLQQF NPAN ++H+ETTGPEIW+ T G++D FV GIG Sbjct: 142 AKGMGGTVKKAYELLENTPNAHMLQQFSNPANTQVHFETTGPEIWEDTNGQVDIFVMGIG 201 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 +GGT++G G+YLK +N NVK+YGVEP ES +L+GGKPGPH I G G GF P +L++D+++ Sbjct: 202 SGGTVSGVGQYLKSKNPNVKIYGVEPSESNVLNGGKPGPHHITGNGVGFKPDILDLDVME 261 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 +V++VSS+++++MAR LALKEGL+VGISSGA AA++LAQ PEN GKL V + PSFGER Sbjct: 262 KVLEVSSEDAVNMARVLALKEGLMVGISSGANTVAALRLAQLPENKGKLIVTVHPSFGER 321 Query: 302 YLSTVLFDATRKEAEAMTFEA 322 YLS+VLF R+EAE M A Sbjct: 322 YLSSVLFQELRQEAENMQPVA 342 >2Q3D-A nrPDB Length = 313 Score = 430 bits (1106), Expect = e-121, Method: Composition-based stats. Identities = 172/304 (56%), Positives = 230/304 (75%), Gaps = 1/304 (0%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 IA+D+T+LIG TPLV L V +G V + AKLE P +SVKDRIG +M+ AE+ GLIK Sbjct: 6 IAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIK 65 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 P +++++EPTSGNTG+ LA AA+GY+ ++TMP +MS ERR++L A+G EL+LT A G Sbjct: 66 P-DTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADG 124 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 M GAIAKAEE+ ++ QQFENPANP IH TT E+W+ T GK+D V+G+GTGG Sbjct: 125 MSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGG 184 Query: 185 TITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVV 244 TITG + +KE+ + + VEP S +LSGG+ GPH IQGIGAGF+P VL+ DL+DE++ Sbjct: 185 TITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEII 244 Query: 245 QVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLS 304 V +++++++AR+LA +EGLLVGISSGAA AA+++A+RPENAGKL V + P FGERYLS Sbjct: 245 TVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLS 304 Query: 305 TVLF 308 T LF Sbjct: 305 TPLF 308 >4LMA-A nrPDB Length = 326 Score = 428 bits (1100), Expect = e-120, Method: Composition-based stats. Identities = 189/313 (60%), Positives = 233/313 (74%), Gaps = 2/313 (0%) Query: 4 RIAKDVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 RIA DVTEL+G TPLV LN + AEGC+GR+ KLE M P +SVKDRIG MI+ AEK G Sbjct: 9 RIAHDVTELVGRTPLVQLNRIPQAEGCLGRIVMKLEGMNPAASVKDRIGTHMINSAEKAG 68 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 LI P +VL+EPTSGNTG+ LA TAAAKGY+LI+TMP +MS ERR +L A+G L LT Sbjct: 69 LINPETTVLVEPTSGNTGIALAMTAAAKGYRLILTMPETMSLERRAMLKAYGATLELTPG 128 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 ++GMKGAI +A++I+ P YMLQQF NP+NP+IH TT EIW+ T G++D V+G+G Sbjct: 129 SQGMKGAILRAQQIVDSIPGAYMLQQFRNPSNPEIHRLTTAEEIWQDTEGQVDFIVAGVG 188 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGTITG + +K + + ++ VEP S ++SGG PGPHKIQGIGAGFIP VL DLID Sbjct: 189 TGGTITGVAEVIKSRKPSFQVVAVEPFNSPVISGGNPGPHKIQGIGAGFIPEVLRTDLID 248 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 EV+ VS +E+ R+LA +EGLL GISSGA AAI+LAQRPEN GKL V I PSFGER Sbjct: 249 EVITVSDEEAFQFGRRLAKEEGLLSGISSGANLCAAIQLAQRPENEGKLIVVIQPSFGER 308 Query: 302 YLSTVLFDATRKE 314 YLST++F + Sbjct: 309 YLSTLMFQNIEER 321 >4I1Y-A nrPDB Length = 314 Score = 419 bits (1077), Expect = e-118, Method: Composition-based stats. Identities = 174/312 (55%), Positives = 230/312 (73%), Gaps = 1/312 (0%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 + IA+++ +LIG TPLV L V +G V AKLE P S+KDRIG +MI AEK G Sbjct: 4 SMTIAENIAQLIGGTPLVRLRRVTDGAAADVVAKLESFNPAGSIKDRIGVAMIDAAEKAG 63 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 LIKP +++++EPTSGNTG+ LA +AA+GYK ++TMP +MS ERR++L A+G ELVLT Sbjct: 64 LIKP-DTIILEPTSGNTGIALAMVSAARGYKCVLTMPDTMSIERRMLLRAYGAELVLTPG 122 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 A+GM GAIAKAEE+ ++ QQFENPANP +H TT E+W+ T GK+D FVSG+G Sbjct: 123 AEGMAGAIAKAEELAKTDDRYFIPQQFENPANPAVHAVTTAEEVWRDTDGKVDIFVSGVG 182 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGTITG + +K++ + + VEP S +LSGG+ GPH IQGIGAGF+P VL++ L+D Sbjct: 183 TGGTITGVAQVIKQRRPSAQFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDLALVD 242 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 EV+ V +D+++++AR++A +EGLL GISSGAA AA +LA RPENAGKL V + P FGER Sbjct: 243 EVITVGNDDALELARRMATEEGLLFGISSGAAVWAARELAHRPENAGKLIVVVLPDFGER 302 Query: 302 YLSTVLFDATRK 313 YLSTVLF + Sbjct: 303 YLSTVLFADLSE 314 >5XA2-A nrPDB Length = 309 Score = 417 bits (1073), Expect = e-117, Method: Composition-based stats. Identities = 172/309 (55%), Positives = 223/309 (72%), Gaps = 3/309 (0%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 I KD +E IG TPLV +N + G RV AK+E P SVK RIG +MI DAE+ G +K Sbjct: 3 IFKDNSESIGRTPLVQINRLTAGLSSRVLAKIEGRNPAYSVKCRIGAAMIWDAEQSGKLK 62 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 PG ++EPTSGNTG+ LAF AA+GYKL +TMP +MS ERR++L +FG +LVLT A G Sbjct: 63 PGM-HVVEPTSGNTGIALAFVCAARGYKLTLTMPETMSIERRMMLKSFGADLVLTPGADG 121 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 MKGAI+KAEE+ A+ P ++ QQF+NPANP IH +TTGPEIW T G++D FV+G+GTGG Sbjct: 122 MKGAISKAEELAAQ-PGWFIPQQFKNPANPAIHVKTTGPEIWNDTEGQVDVFVAGVGTGG 180 Query: 185 TITGAGKYLK-EQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 TITG ++LK E+ V + VEP S +L+GG G HKIQGIGAGF+P + ++DE+ Sbjct: 181 TITGVARFLKHEKKHPVHVVAVEPAASPVLAGGPAGRHKIQGIGAGFVPDTFDRSVVDEI 240 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 + V+ DE+I+ AR+LA++EG+ GIS GAA A A+K+A RPE AGK V + P GERYL Sbjct: 241 LSVTDDEAIETARKLAMEEGISCGISCGAAMAGALKVAARPEFAGKTIVTVLPDAGERYL 300 Query: 304 STVLFDATR 312 ST LF+ R Sbjct: 301 STALFENLR 309 >4LMB-A nrPDB Length = 322 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 180/311 (57%), Positives = 225/311 (72%), Gaps = 2/311 (0%) Query: 5 IAKDVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 IA+D+T+L+G TPLV LN + AEG R+ KLE M P +SVKDRIG SM+ DAE GL Sbjct: 10 IARDITQLVGRTPLVQLNRIPVAEGVKARIVVKLESMNPAASVKDRIGVSMVEDAEAAGL 69 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 I P +++L+EPTSGNTG+ LA AAAKGY+L++TMP +MS ERR +L A+G +L LT + Sbjct: 70 IHPDKTILVEPTSGNTGIALAMVAAAKGYRLVLTMPETMSLERRAMLKAYGAQLELTPGS 129 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 +GM+GAI +AEEI+ TPN Y LQQF NPANPKIH ETT EIW T G +D + G+GT Sbjct: 130 QGMEGAITRAEEIVENTPNAYSLQQFRNPANPKIHRETTAEEIWADTDGLVDIVIGGVGT 189 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 242 GGTITG + +K + + VEP S +LSGG+PGPHKIQGIGAGFIP++ +LIDE Sbjct: 190 GGTITGIAETIKPRRPQFQAIAVEPSNSPVLSGGQPGPHKIQGIGAGFIPAIFRPELIDE 249 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 V+ V E+ AR+LA +EGLL GIS+GAA AAI++ +RPEN KL V I PSFGERY Sbjct: 250 VIIVDDTEAFAYARRLARQEGLLSGISAGAALWAAIQVGKRPENEDKLIVMIQPSFGERY 309 Query: 303 LSTVLFDATRK 313 LST LF Sbjct: 310 LSTALFKDLED 320 >4COO-A nrPDB Length = 563 Score = 413 bits (1063), Expect = e-116, Method: Composition-based stats. Identities = 122/324 (37%), Positives = 186/324 (57%), Gaps = 12/324 (3%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEK 59 + +I D+ + IG+TP+V +N + + G + AK E SVKDRI MI DAE+ Sbjct: 95 SPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAER 154 Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 G +KPG+++ IEPTSGNTG+GLA AA +GY+ II MP MS+E+ +L A G E+V T Sbjct: 155 DGTLKPGDTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT 213 Query: 120 DPAKGM---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGF 176 + + A + + PN ++L Q+ N +NP HY+TT EI + GK+D Sbjct: 214 PTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDML 273 Query: 177 VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVES-----AILSGGKPGPHKIQGIGAGFI 231 V+ +GTGGTITG + LKE+ ++ GV+P S L+ + ++++GIG FI Sbjct: 274 VASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFI 333 Query: 232 PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLF 291 P+VL+ ++D+ + + +E+ AR L +EGLL G S+G+ A A+K AQ + G+ Sbjct: 334 PTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ-EGQRC 392 Query: 292 VAIFPSFGERYLSTVLFDATRKEA 315 V I P Y++ L D + Sbjct: 393 VVILPDSVRNYMTKFLSDRWMLQK 416 >1M54-A nrPDB Length = 363 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 122/324 (37%), Positives = 186/324 (57%), Gaps = 12/324 (3%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEK 59 + +I D+ + IG+TP+V +N + + G + AK E SVKDRI MI DAE+ Sbjct: 30 SPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAER 89 Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 G +KPG+++ IEPTSGNTG+GLA AA +GY+ II MP MS+E+ +L A G E+V T Sbjct: 90 DGTLKPGDTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT 148 Query: 120 DPAKGM---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGF 176 + + A + + PN ++L Q+ N +NP HY+TT EI + GK+D Sbjct: 149 PTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDML 208 Query: 177 VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVES-----AILSGGKPGPHKIQGIGAGFI 231 V+ +GTGGTITG + LKE+ ++ GV+P S L+ + ++++GIG FI Sbjct: 209 VASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFI 268 Query: 232 PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLF 291 P+VL+ ++D+ + + +E+ AR L +EGLL G S+G+ A A+K AQ + G+ Sbjct: 269 PTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ-EGQRC 327 Query: 292 VAIFPSFGERYLSTVLFDATRKEA 315 V I P Y++ L D + Sbjct: 328 VVILPDSVRNYMTKFLSDRWMLQK 351 >5MMS-A nrPDB Length = 408 Score = 410 bits (1053), Expect = e-115, Method: Composition-based stats. Identities = 122/324 (37%), Positives = 186/324 (57%), Gaps = 12/324 (3%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEK 59 + +I D+ + IG+TP+V +N + + G + AK E SVKDRI MI DAE+ Sbjct: 73 SPKILPDILKKIGDTPMVRINKIGKKFGLKCELLAKCEFFNAGGSVKDRISLRMIEDAER 132 Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 G +KPG+++ IEPTSGNTG+GLA AA +GY+ II MP MS+E+ +L A G E+V T Sbjct: 133 DGTLKPGDTI-IEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIVRT 191 Query: 120 DPAKGM---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGF 176 + + A + + PN ++L Q+ N +NP HY+TT EI + GK+D Sbjct: 192 PTNARFDSPESHVGVAWRLKNEIPNSHILDQYRNASNPLAHYDTTADEILQQCDGKLDML 251 Query: 177 VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVES-----AILSGGKPGPHKIQGIGAGFI 231 V+ +GTGGTITG + LKE+ ++ GV+P S L+ + ++++GIG FI Sbjct: 252 VASVGTGGTITGIARKLKEKCPGCRIIGVDPEGSILAEPEELNQTEQTTYEVEGIGYDFI 311 Query: 232 PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLF 291 P+VL+ ++D+ + + +E+ AR L +EGLL G S+G+ A A+K AQ + G+ Sbjct: 312 PTVLDRTVVDKWFKSNDEEAFTFARMLIAQEGLLCGGSAGSTVAVAVKAAQELQ-EGQRC 370 Query: 292 VAIFPSFGERYLSTVLFDATRKEA 315 V I P Y++ L D + Sbjct: 371 VVILPDSVRNYMTKFLSDRWMLQK 394 >3T4P-A nrPDB Length = 334 Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats. Identities = 158/317 (49%), Positives = 219/317 (69%), Gaps = 1/317 (0%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 + +A+ + +LIG TP +YLN + +V K+E P +SVKDR+GF++ AEK+G Sbjct: 8 SKNVAQSIDQLIGQTPALYLNKL-NNTKAKVVLKMECENPMASVKDRLGFAIYDKAEKEG 66 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 + PG+S+++E +SGNTGV LA A +GYK+IITMP SMS ERR +L FG E++LT Sbjct: 67 KLIPGKSIVVESSSGNTGVSLAHLGAIRGYKVIITMPESMSLERRCLLRIFGAEVILTPA 126 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 A GMKGA+A A++I+A PN + QF N IH ETTGPEIW+ T +D F++G+G Sbjct: 127 ALGMKGAVAMAKKIVAANPNAVLADQFATKYNALIHEETTGPEIWEQTNHNVDCFIAGVG 186 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGT+TG + LK+ ++ ++ VEP ES +LSGGKPGPHKIQGIG GF+P VL+ LID Sbjct: 187 TGGTLTGVARALKKMGSHARIVAVEPTESPVLSGGKPGPHKIQGIGPGFVPDVLDRSLID 246 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 EV+ V+ D++I+ A +L +G+ G S GA AA+K+A+RPE GK V + PSFGER Sbjct: 247 EVLCVAGDDAIETALKLTRSDGVFCGFSGGANVYAALKIAERPEMEGKTIVTVIPSFGER 306 Query: 302 YLSTVLFDATRKEAEAM 318 YLST L+ + R E ++ Sbjct: 307 YLSTTLYRSVRDEVSSL 323 >2BHS-A nrPDB Length = 303 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 134/305 (43%), Positives = 188/305 (61%), Gaps = 11/305 (3%) Query: 6 AKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP 65 + + IGNTPLV L + V KLE P SVKDR SMI +AEK+G IKP Sbjct: 1 MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKP 60 Query: 66 GESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGM 125 G+ VLIE TSGNTG+ LA AA KGY++ + MP +MS ERR + A+G EL+L +GM Sbjct: 61 GD-VLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGM 119 Query: 126 KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGT 185 +GA A E +A G +L QF NP NP HY TTGPEIW+ TGG+I FVS +GT GT Sbjct: 120 EGARDLALE-MANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGT 178 Query: 186 ITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQ 245 ITG ++++EQ+ V + G++P E + + G + P + ++P + N L+DEV+ Sbjct: 179 ITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTE-------YLPGIFNASLVDEVLD 231 Query: 246 VSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLST 305 + ++ + R+LA++EG+ G+SSG A A A+++A+ N + VAI G+RYLST Sbjct: 232 IHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAK--ANPDAVVVAIICDRGDRYLST 289 Query: 306 VLFDA 310 +F Sbjct: 290 GVFGE 294 >3FCA-A nrPDB Length = 291 Score = 389 bits (999), Expect = e-109, Method: Composition-based stats. Identities = 155/297 (52%), Positives = 199/297 (67%), Gaps = 10/297 (3%) Query: 9 VTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGES 68 + LIG+TP+V L+++ R+A KLE P SVKDR MI DAEK+GL+K G Sbjct: 2 MERLIGSTPIVRLDSID----SRIALKLEKNNPGGSVKDRPALFMILDAEKRGLLKNG-- 55 Query: 69 VLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGA 128 ++EPTSGN G+ +A A +G+++I+TMP +MS ERR +L G ELVLT GMKGA Sbjct: 56 -IVEPTSGNMGIAIAMIGAKRGHRVILTMPETMSVERRKVLKMLGAELVLTPGELGMKGA 114 Query: 129 IAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITG 188 + KA EI +T +ML QFENP N H TTGPEI K +ID FV+G+GTGGTI+G Sbjct: 115 VEKALEISRET-GAHMLNQFENPYNVYSHQFTTGPEILKQMDYQIDAFVAGVGTGGTISG 173 Query: 189 AGKYLKEQNAN-VKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVS 247 G+ LK N VK+ VEP +S +LSGG+PG H IQGIGAGF+P +L+ +IDEV+ V Sbjct: 174 VGRVLKGFFGNGVKIVAVEPAKSPVLSGGQPGKHAIQGIGAGFVPKILDRSVIDEVITVE 233 Query: 248 SDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLS 304 +E+ +MAR LA KEGLLVGISSGA AAA+K+AQ+ V + P ERYLS Sbjct: 234 DEEAYEMARYLAKKEGLLVGISSGANVAAALKVAQK-LGPDARVVTVAPDHAERYLS 289 >5OHX-A nrPDB Length = 504 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 136/327 (41%), Positives = 195/327 (59%), Gaps = 11/327 (3%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKK 60 ++I D+ IG TPL+ LNN+ + G + AK E + P SVKDRI + MI DAE K Sbjct: 33 TKIMPDILTAIGQTPLIKLNNIPKSYGIKCEIYAKCEFLNPGGSVKDRIAYRMIQDAEDK 92 Query: 61 GLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 GL+KPG ++ IEPTSGNTG+GLA AA +GYK II MP MS E+ L A G +++ T Sbjct: 93 GLLKPGCTI-IEPTSGNTGIGLAMAAAVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTP 151 Query: 121 PAKGM---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 + I+ A+++ + PN +L Q+ NP NP HY+ T EIWK GKID V Sbjct: 152 TEASWHSPEAHISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLV 211 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVES----AILSGGKPGPHKIQGIGAGFIPS 233 +G GTGGTI+G G+ LKE + N+K+ V+P S + S + G ++++GIG FIP+ Sbjct: 212 AGAGTGGTISGIGRKLKELSPNIKIIAVDPKGSILDPSSDSQNEVGFYEVEGIGYDFIPT 271 Query: 234 VLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVA 293 VL+ ++ID+ ++ +ES++ AR L +EGLL G SSGAA AA+K+A+ K V Sbjct: 272 VLDRNVIDKWIKTEDNESLNAARMLIRQEGLLCGGSSGAALIAALKIAKDIPEE-KRMVI 330 Query: 294 IFPSFGERYLSTVLFDATRKEAEAMTF 320 I P YL+ + + + + Sbjct: 331 ILPDGIRNYLTKFVSEYWMETRGFLQP 357 >2JC3-A nrPDB Length = 303 Score = 388 bits (997), Expect = e-108, Method: Composition-based stats. Identities = 132/305 (43%), Positives = 187/305 (61%), Gaps = 11/305 (3%) Query: 6 AKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP 65 + + IGNTPLV L + + KLE P SVKDR SMI +AEK+G IKP Sbjct: 1 MNTLEQTIGNTPLVKLQRIGPDNGSEIWVKLEGNNPAGSVKDRAALSMIVEAEKRGEIKP 60 Query: 66 GESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGM 125 G+ VLIE TSGNTG+ LA AA KGY++ + MP +MS ERR + A+G EL+L +GM Sbjct: 61 GD-VLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGM 119 Query: 126 KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGT 185 +GA A +++ G +L QF NP NP HY TTGPEIW+ T G+I FVS +GT GT Sbjct: 120 EGARDLALA-MSERGEGKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGT 178 Query: 186 ITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQ 245 ITG ++L+EQ V + G++P E + + G + P A ++P + N L+DEV+ Sbjct: 179 ITGVSRFLREQEKPVTIVGLQPEEGSSIPGIRRWP-------AEYMPGIFNASLVDEVLD 231 Query: 246 VSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLST 305 + +++ + R+LA++EG+ G+SSG A A A+++A+ G + VAI G+RYLST Sbjct: 232 IHQNDAENTMRELAVREGIFCGVSSGGAVAGALRVAR--ATPGAIVVAIICDRGDRYLST 289 Query: 306 VLFDA 310 +F Sbjct: 290 GVFGE 294 >5XW3-A nrPDB Length = 315 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 135/311 (43%), Positives = 190/311 (61%), Gaps = 3/311 (0%) Query: 4 RIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLI 63 + + V ELIG+TP+V + + R+ AKLE P SVKDR+G +I DA +KGL+ Sbjct: 2 NVYRGVHELIGHTPIVEITRFSLPEGVRLFAKLEFYNPGGSVKDRLGRELIEDALEKGLV 61 Query: 64 KPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 123 G ++ IEPT+GNTG+GLA A ++I+ +P S E++ ++ A G +V T + Sbjct: 62 TEGGTI-IEPTAGNTGIGLALAALQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPTEQ 120 Query: 124 GMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTG 183 GM GAIAKA+E++ + PN Y QF N ANP+ +++T GPE+W G+I+ FV+G GTG Sbjct: 121 GMTGAIAKAKELVNEIPNSYSPSQFANEANPRAYFKTLGPELWSALNGEINIFVAGAGTG 180 Query: 184 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 GT G YLKE+N ++K VEP E +IL+GGK G H+ +GIG FIP L DE+ Sbjct: 181 GTFMGTASYLKEKNIDIKTVIVEP-EGSILNGGKAGSHETEGIGLEFIPPFLKTSYFDEI 239 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 +S + ++LA KEGLLVG SSGAA A++ A++ G V IFP ERYL Sbjct: 240 HTISDRNAFLRVKELAQKEGLLVGSSSGAAFHASLLEAEKAA-PGTNIVTIFPDSSERYL 298 Query: 304 STVLFDATRKE 314 S ++ E Sbjct: 299 SKDIYKGWELE 309 >5J5V-A nrPDB Length = 323 Score = 386 bits (991), Expect = e-107, Method: Composition-based stats. Identities = 174/325 (53%), Positives = 226/325 (69%), Gaps = 13/325 (4%) Query: 4 RIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLI 63 +I +D + IG+TPLV LN + G R+ AK+E P SVK RIG +MI DAEK+G++ Sbjct: 3 KIFEDNSLTIGHTPLVRLNRIGNG---RILAKVESRNPSFSVKCRIGANMIWDAEKRGVL 59 Query: 64 KPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 123 KPG L+EPTSGNTG+ LA+ AAA+GYKL +TMP +MS ERR +L A G LVLT+ AK Sbjct: 60 KPGVE-LVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRKLLKALGANLVLTEGAK 118 Query: 124 GMKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 GMKGAI KAEEI+A P Y+L QQF NPANP+IH +TTGPEIW+ T G++D F++G+GT Sbjct: 119 GMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPEIWEDTDGQVDVFIAGVGT 178 Query: 183 GGTITGAGKYLKEQNANVKL--YGVEPVESAILSGG------KPGPHKIQGIGAGFIPSV 234 GGT+TG +Y+K L VEP +S +++ KPGPHKIQGIGAGFIP+ Sbjct: 179 GGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGEEIKPGPHKIQGIGAGFIPAN 238 Query: 235 LNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAI 294 L++ L+D+V+ ++++E+I AR+L +EG+L GISSGAA AAA+KL + K V I Sbjct: 239 LDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGAAVAAALKLQEDESFTNKNIVVI 298 Query: 295 FPSFGERYLSTVLFDATRKEAEAMT 319 PS GERYLST LF E E Sbjct: 299 LPSSGERYLSTALFADLFTEKELQQ 323 >4OFX-A nrPDB Length = 319 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 133/312 (42%), Positives = 193/312 (61%), Gaps = 5/312 (1%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + ++ ++IG TP+V L+ + + + K E + P SVKDRIG +MI AEK+G IK Sbjct: 5 VLDNILQVIGKTPVVRLHRIGQSLPCELYGKCEFLNPGGSVKDRIGAAMIESAEKQGKIK 64 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 PG++ LIEPTSGNTG+G+A A KGY++IITMP MS E++++L A G + T Sbjct: 65 PGDT-LIEPTSGNTGIGIALAGAVKGYRVIITMPEKMSHEKQVVLEALGATIYRTPTEAA 123 Query: 125 M---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIG 181 + I+ A+ + + PN Y+L Q+ N NP IHY+TTG EI G + V G+G Sbjct: 124 YDDPESHISLAKRLNQEIPNSYILDQYSNAENPDIHYQTTGQEILDDMGENLSMVVMGVG 183 Query: 182 TGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 TGGTI G K LKE N ++++ GV+P+ S + G + P+ ++GIG FIP VL+ +LID Sbjct: 184 TGGTIIGVAKKLKEVNPSIQIIGVDPIGSILGGGDEIKPYLVEGIGYDFIPEVLDNNLID 243 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGER 301 E ++++ +S MAR+L +EGLLVG SSG+A AA + AQR G+ + I P Sbjct: 244 EYIKINDKDSFLMARRLIREEGLLVGGSSGSAVWAACQAAQR-LKEGERCLVILPDAIRN 302 Query: 302 YLSTVLFDATRK 313 YL+ + DA K Sbjct: 303 YLTKFVDDAWMK 314 >2EFY-A nrPDB Length = 304 Score = 383 bits (984), Expect = e-107, Method: Composition-based stats. Identities = 151/303 (49%), Positives = 204/303 (67%), Gaps = 3/303 (0%) Query: 9 VTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGE- 67 V IG TP+V L V E + V KLE + P S+KDR + MI DAE++G+++PG Sbjct: 3 VEGAIGKTPVVRLAKVVEPDMAEVWVKLEGLNPGGSIKDRPAWYMIKDAEERGILRPGSG 62 Query: 68 SVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKG 127 V++EPTSGNTG+GLA AA++GY+LI+TMPA MS ER+ +L AFG ELVLTDP + M Sbjct: 63 QVIVEPTSGNTGIGLAMIAASRGYRLILTMPAQMSEERKRVLKAFGAELVLTDPERRMLA 122 Query: 128 AIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTIT 187 A +A + + +M QF+NPAN + HYETTGPE+++ G+ID FV G GTGGTIT Sbjct: 123 AREEALRL-KEELGAFMPDQFKNPANVRAHYETTGPELYEALEGRIDAFVYGSGTGGTIT 181 Query: 188 GAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVS 247 G G+YLKE+ +VK+ VEP S +LSGGK G H QG+G GFIP L++ L+D V+QV Sbjct: 182 GVGRYLKERIPHVKVIAVEPARSNVLSGGKMGQHGFQGMGPGFIPENLDLSLLDGVIQVW 241 Query: 248 SDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVL 307 +++ +AR+LA +EGL +G+SSG AA+++A R GK I P G +YLST L Sbjct: 242 EEDAFPLARRLAREEGLFLGMSSGGIVWAALQVA-RELGPGKRVACISPDGGWKYLSTPL 300 Query: 308 FDA 310 + Sbjct: 301 YAE 303 >3PC3-A nrPDB Length = 527 Score = 382 bits (982), Expect = e-107, Method: Composition-based stats. Identities = 123/321 (38%), Positives = 182/321 (56%), Gaps = 12/321 (3%) Query: 3 SRIAKDVTELIGNTPLVYLNNV--AEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKK 60 +I ++ E+IG TPLV LNN+ ++G + AK E + P SVKDRIG+ M+ DAE++ Sbjct: 48 QQITPNILEVIGCTPLVKLNNIPASDGIECEMYAKCEFLNPGGSVKDRIGYRMVQDAEEQ 107 Query: 61 GLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 GL+KPG ++ IEPTSGNTG+GLA A KGYK II MP MS E+ L G +++ T Sbjct: 108 GLLKPGYTI-IEPTSGNTGIGLAMACAVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTP 166 Query: 121 PAKGM---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 +G I A+++ +TPN +L Q+ N NP HY+ T EI K+D V Sbjct: 167 TEAAYDSPEGLIYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIV 226 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVES-----AILSGGKPGPHKIQGIGAGFIP 232 GT GTI+G G+ +KEQ + ++ GV+P S A L+ ++++GIG F P Sbjct: 227 VSAGTAGTISGIGRKIKEQVPSCQIVGVDPYGSILARPAELNKTDVQFYEVEGIGYDFPP 286 Query: 233 SVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFV 292 +V + ++D ++ + M+R+L +EGLL G SSG A AA++ A R G+ V Sbjct: 287 TVFDDTVVDVWTKIGDSDCFPMSRRLNAEEGLLCGGSSGGAMHAALEHA-RKLKKGQRCV 345 Query: 293 AIFPSFGERYLSTVLFDATRK 313 I P Y++ + D + Sbjct: 346 VILPDGIRNYMTKFVSDNWME 366 >6C2H-A nrPDB Length = 375 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 127/325 (39%), Positives = 178/325 (54%), Gaps = 17/325 (5%) Query: 7 KDVTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 +V +L+GNTPL+ L + + G ++ AKLE+ P S+KDRI SM+ +AE G I Sbjct: 34 HNVIDLVGNTPLIALKKLPKALGIKPQIYAKLELYNPGGSIKDRIAKSMVEEAEASGRIH 93 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 P S LIEPTSGNTG+GLA A KGY+ IIT+P MS E+ +L A G E++ T A Sbjct: 94 PSRSTLIEPTSGNTGIGLALIGAIKGYRTIITLPEKMSNEKVSVLKALGAEIIRTPTAAA 153 Query: 125 M---KGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTG-----GKIDGF 176 + I A+++ + P +L Q+ N NP+ HY TG EI + + Sbjct: 154 WDSPESHIGVAKKLEKEIPGAVILDQYNNMMNPEAHYFGTGREIQRQLEDLNLFDNLRAV 213 Query: 177 VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAI-----LSGGKPGPHKIQGIGAGFI 231 V+G GTGGTI+G KYLKEQN +++ G +P S + L+ +K++GIG F+ Sbjct: 214 VAGAGTGGTISGISKYLKEQNDKIQIVGADPFGSILAQPENLNKTDITDYKVEGIGYDFV 273 Query: 232 PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQR--PENAGK 289 P VL+ LID + S ARQL EG+LVG SSG+A A +K + Sbjct: 274 PQVLDRKLIDVWYKTDDKPSFKYARQLISNEGVLVGGSSGSAFTAVVKYCEDHPELTEDD 333 Query: 290 LFVAIFPSFGERYLSTVLFDATRKE 314 + VAIFP YL+ + D K+ Sbjct: 334 VIVAIFPDSIRSYLTKFVDDEWLKK 358 >2EGU-A nrPDB Length = 308 Score = 379 bits (974), Expect = e-106, Method: Composition-based stats. Identities = 172/307 (56%), Positives = 224/307 (72%), Gaps = 3/307 (0%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 +R +TELIG+TP V LN + + V KLE M P SSVKDRI +MI AEK G Sbjct: 2 ARTVNSITELIGDTPAVKLNRIVDEDSADVYLKLEFMNPGSSVKDRIALAMIEAAEKAGK 61 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 +KPG+++ +EPTSGNTG+GLA AAAKGYK ++ MP +MS ERR +L A+G ELVLT A Sbjct: 62 LKPGDTI-VEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAELVLTPGA 120 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 +GM+GAIAKAEE++ + +M QQF+N ANP+IH TTG EI + G ++D FV+G+GT Sbjct: 121 QGMRGAIAKAEELVREH-GYFMPQQFKNEANPEIHRLTTGKEIVEQMGDQLDAFVAGVGT 179 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 242 GGTITGAGK L+E N+K+Y VEP +S +LSGGKPGPHKIQGIGAGF+P +L+ + D Sbjct: 180 GGTITGAGKVLREAYPNIKIYAVEPADSPVLSGGKPGPHKIQGIGAGFVPDILDTSIYDG 239 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 V+ V+++E+ AR+ A +EG+L GISSGAA AA+K+A+ GK +AI PS GERY Sbjct: 240 VITVTTEEAFAAARRAAREEGILGGISSGAAIHAALKVAKE-LGKGKKVLAIIPSNGERY 298 Query: 303 LSTVLFD 309 LST L+ Sbjct: 299 LSTPLYQ 305 >2PQM-A nrPDB Length = 343 Score = 373 bits (958), Expect = e-104, Method: Composition-based stats. Identities = 144/322 (44%), Positives = 201/322 (62%), Gaps = 8/322 (2%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGC----VGRVAAKLEMMEPCSSVKDRIGFSMISDAE 58 RI ++ E IG TPLV L+ V E R+ KLE P SSVKDR+GF+++ A Sbjct: 11 KRIYHNILETIGGTPLVELHGVTEHPRIKKGTRILVKLEYFNPMSSVKDRVGFNIVYQAI 70 Query: 59 KKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVL 118 K G +KPG + IE TSGNTG+ L A GY++ I MP++MS ER++I+ AFG EL+L Sbjct: 71 KDGRLKPGMEI-IESTSGNTGIALCQAGAVFGYRVNIAMPSTMSVERQMIMKAFGAELIL 129 Query: 119 TDPAKGMKGAIAKAEEILAKTPNGYML-QQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 T+ KGM GAI + +++ + P Y + QF NP N H+ T EIW+ T G++D V Sbjct: 130 TEGKKGMPGAIEEVNKMIKENPGKYFVANQFGNPDNTAAHHY-TANEIWEDTDGEVDIVV 188 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNV 237 S +GT GT+ G + LKE+ +K+ VEP ESA+L G GPH IQGIGAGFIP + Sbjct: 189 SAVGTSGTVIGVAEKLKEKKKGIKIIAVEPEESAVLEGKAKGPHGIQGIGAGFIPDIYKK 248 Query: 238 DLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPS 297 + +DE++ + + ++ MAR + +G++ G+SSGAA A +K A++PEN GK V I PS Sbjct: 249 EFVDEIIPIKTQDAWKMARAVVKYDGIMCGMSSGAAILAGLKEAEKPENEGKTIVIIVPS 308 Query: 298 FGERYLSTVLFDATRKEAEAMT 319 GERYLST L+ + E + Sbjct: 309 CGERYLSTDLYK-IKDEGTKIQ 329 >5XEM-A nrPDB Length = 310 Score = 363 bits (932), Expect = e-101, Method: Composition-based stats. Identities = 137/304 (45%), Positives = 188/304 (61%), Gaps = 4/304 (1%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 +A V +LIGNTPLV +NN+ + + KLE P S KDRI MI +AEK+GLI Sbjct: 6 LANSVIDLIGNTPLVKINNI-DTFGNEIYVKLEGSNPGRSTKDRIALKMIEEAEKEGLID 64 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 ++V+IE TSGNTG+GLA A K YKL I MP +MS ER ++ A+G E++LTD + G Sbjct: 65 K-DTVIIEATSGNTGIGLAMICAVKNYKLKIVMPDTMSIERIQLMRAYGTEVILTDGSLG 123 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 MK + K EE+ ++ QF N NPK HYETT EI K K+D F+ G GTGG Sbjct: 124 MKACLEKLEELKKNEKKYFVPNQFTNVNNPKAHYETTAEEILKDLNNKVDVFICGTGTGG 183 Query: 185 TITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGA--GFIPSVLNVDLIDE 242 + +G K LKE+ N+K + VEP S +LS G GPHKIQG+G G IP+V + L D+ Sbjct: 184 SFSGTAKKLKEKLPNIKTFPVEPASSPLLSKGYIGPHKIQGMGMSIGGIPAVYDGSLADD 243 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 ++ D++ +M R+L+ KEG+L GIS+GA AA+ ++ + G V + GE+Y Sbjct: 244 ILVCEDDDAFEMMRELSFKEGILGGISTGATFKAALDYSKENADKGLKIVVLSTDSGEKY 303 Query: 303 LSTV 306 LS + Sbjct: 304 LSNI 307 >6AHI-A nrPDB Length = 314 Score = 363 bits (931), Expect = e-101, Method: Composition-based stats. Identities = 129/306 (42%), Positives = 178/306 (58%), Gaps = 5/306 (1%) Query: 5 IAKDVTELIGNTPLVYLNN--VAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 I + + IG TP+ N + AKLE + P SVKDR+G +I + K G Sbjct: 3 IITTMQDAIGRTPVFKFTNKDYPIPLNSAIYAKLEHLNPGGSVKDRLGQYLIGEGFKTGK 62 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 I ++ +IEPT+GNTG+ LA A K I +P STE++ I+ A G ++ T + Sbjct: 63 IT-SKTTIIEPTAGNTGIALALVAIKHHLKTIFVVPEKFSTEKQQIMRALGALVINTPTS 121 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 +G+ GAI K++E+ P+ Y+ QFENP NP +Y T PEI + G + FV+GIG+ Sbjct: 122 EGISGAIKKSKELAESIPDSYLPLQFENPDNPAAYYHTLAPEIVQELGTNLTSFVAGIGS 181 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDE 242 GGT G +YLKE+ ++L GVEP E +IL+GG+PGPH+I+GIG FIP ID Sbjct: 182 GGTFAGTARYLKERIPAIRLIGVEP-EGSILNGGEPGPHEIEGIGVEFIPPFFENLDIDG 240 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 +S +E R+LA K GLLVG SSGAA AA+K AQR G + IFP +RY Sbjct: 241 FETISDEEGFSYTRKLAKKNGLLVGSSSGAAFVAALKEAQRLP-EGSQVLTIFPDVADRY 299 Query: 303 LSTVLF 308 LS ++ Sbjct: 300 LSKGIY 305 >5XCN-X nrPDB Length = 350 Score = 350 bits (898), Expect = 5e-97, Method: Composition-based stats. Identities = 172/318 (54%), Positives = 217/318 (68%), Gaps = 11/318 (3%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 + I D + IGNTPLV L + G G V K+E P SVK RIG +M+ AEK G Sbjct: 34 SMAIYADNSYSIGNTPLVRLKHF--GHNGNVVVKIEGRNPSYSVKCRIGANMVWQAEKDG 91 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDP 121 + G+ + ++ TSGNTG+ LA+ AAA+GYK+ +TMP +MS ER+ +L GV LVLT+ Sbjct: 92 TLTKGKEI-VDATSGNTGIALAYVAAARGYKITLTMPETMSLERKRLLCGLGVNLVLTEG 150 Query: 122 AKGMKGAIAKAEEILAKTPNGY-MLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGI 180 AKG KGAIAKAEEI+A P+ Y ML+QFENPANP+IH ETTGPEIWK T GK+D V+G+ Sbjct: 151 AKGAKGAIAKAEEIVASDPSRYVMLKQFENPANPQIHRETTGPEIWKDTDGKVDVVVAGV 210 Query: 181 GTGGTITGAGKYLK-EQNANVKLYGVEPVESAILSGG------KPGPHKIQGIGAGFIPS 233 GTGG+ITG + +K + + VEPVES ++S KPGPHKIQGIGAGFIP Sbjct: 211 GTGGSITGISRAIKLDFGKQITSVAVEPVESPVISQTLAGEEVKPGPHKIQGIGAGFIPK 270 Query: 234 VLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVA 293 L++ +ID V V SD ++ AR+L +EG+L GISSGAA AAA +LA+ PE A KL V Sbjct: 271 NLDLSIIDRVETVDSDTALATARRLMAEEGILAGISSGAAVAAADRLAKLPEFADKLIVV 330 Query: 294 IFPSFGERYLSTVLFDAT 311 I PS ERYLST LF+ Sbjct: 331 ILPSASERYLSTALFEGI 348 >3X43-A nrPDB Length = 332 Score = 345 bits (886), Expect = 1e-95, Method: Composition-based stats. Identities = 127/310 (40%), Positives = 189/310 (60%), Gaps = 5/310 (1%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + + + IG TP+V L +A V K+E P SVKDR+ S++ DAE KGL+K Sbjct: 3 LFNSILDTIGRTPIVRLQRMAPEHTS-VYVKVESFNPGGSVKDRLALSVVLDAEAKGLLK 61 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 PG+++ +E TSGN G+ LA AAA+GY+ + M + S ERR ++ A+G +LVL G Sbjct: 62 PGDTI-VECTSGNVGIALAMVAAARGYRFVAVMGDTYSVERRKLIRAYGGKLVLFPGHLG 120 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGK-IDGFVSGIGTG 183 KG A+E+ A+ + +QF+NPANP H ETT EI GK +D FV+G GT Sbjct: 121 SKGGNLIADEL-AEKYGWFRARQFDNPANPSYHRETTASEILADFAGKRLDHFVTGFGTT 179 Query: 184 GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEV 243 GT+TG G+ L+ V++ +EP +A+L+ G+ PH+IQG+ F+P VL+ +ID++ Sbjct: 180 GTLTGVGQMLRVARPEVRVVALEPSNAAMLARGEWSPHQIQGLAPNFVPGVLDRSVIDDL 239 Query: 244 VQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYL 303 V + + D +R+LA +EG+ GIS+GA A A+ +A+ G + +A+ P GERYL Sbjct: 240 VTMDEVTARDTSRRLAAEEGIFAGISAGATVATALSIAEHAP-EGTVLLAMLPDTGERYL 298 Query: 304 STVLFDATRK 313 ST LFD + Sbjct: 299 STFLFDGVDE 308 >5D84-A nrPDB Length = 326 Score = 342 bits (878), Expect = 1e-94, Method: Composition-based stats. Identities = 105/322 (32%), Positives = 161/322 (50%), Gaps = 9/322 (2%) Query: 2 ASRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKG 61 + + + +G TP+V L+ + V AKLE M P S+KDR +I K G Sbjct: 5 SQACHDSLLDSVGQTPMVQLHQLFP--KHEVFAKLEYMNPGGSMKDRPAKYIIEHGIKHG 62 Query: 62 LIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGV--ELVLT 119 LI + LIE TSGN G+ LA A KG KL + +S I+ ++G E+V Sbjct: 63 LITEN-THLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGANVEMVEE 121 Query: 120 DPAKG--MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 A G + IAK +E+LA + Y + Q+ N N + HY G EI + ID FV Sbjct: 122 PDAHGGYLMTRIAKVQELLATIDDAYWINQYANELNWQSHYHGAGTEIVETIKQPIDYFV 181 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNV 237 + + T G+I G + +KE + N ++ V+ + +++ G KP ++ GIGA +P +LN Sbjct: 182 APVSTTGSIMGMSRKIKEVHPNAQIVAVD-AKGSVIFGDKPINRELPGIGASRVPEILNR 240 Query: 238 DLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPS 297 I++V+ V +S R+L EG+ G S+G+ AA +L E G V I P Sbjct: 241 SEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTGSIIAAIEQLITSIE-EGATIVTILPD 299 Query: 298 FGERYLSTVLFDATRKEAEAMT 319 G+RYL V D ++ ++ Sbjct: 300 RGDRYLDLVYSDTWLEKMKSRQ 321 >5JJC-A nrPDB Length = 342 Score = 341 bits (875), Expect = 2e-94, Method: Composition-based stats. Identities = 114/316 (36%), Positives = 168/316 (53%), Gaps = 15/316 (4%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + V + IGNTPL+ L+ +E + K E + P SVKDR +I DAEK+GL++ Sbjct: 1 MFNSVLDTIGNTPLIRLSKASELTGCDIYGKAEFLNPGQSVKDRAALYIIRDAEKRGLLR 60 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD---- 120 PG V++E T+GNTG+GL A A GY+ I +P + S E++ L G EL+ Sbjct: 61 PGG-VIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAELIEVPAAPY 119 Query: 121 --PAKGMKGAIAKAEEILAKTPNG-YMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFV 177 P ++ + AE++ PNG QF+N N + H ETT EIW+ T +IDGFV Sbjct: 120 RNPNNAVRLSGRLAEQLAKTEPNGAIWANQFDNTVNRQAHIETTAQEIWRDTSDQIDGFV 179 Query: 178 SGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHK------IQGIGAGFI 231 + +G+GGT+ G LKE+N N+K+ +P +A+ + G K +GIG G I Sbjct: 180 AAVGSGGTLAGTAIGLKERNHNIKIALADPHGAALHAFYTTGELKAEGDSITEGIGQGRI 239 Query: 232 PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLF 291 + L D Q+ E++D+ L +EGL +G SSG A AI+LA+ G Sbjct: 240 TANLEGFTPDFSYQIPDAEALDILFALVEEEGLCLGGSSGINIAGAIRLAK-DLGPGHTI 298 Query: 292 VAIFPSFGERYLSTVL 307 V + +G RY S + Sbjct: 299 VTVLCDYGNRYQSKLF 314 >5B1I-A nrPDB Length = 311 Score = 339 bits (869), Expect = 1e-93, Method: Composition-based stats. Identities = 122/304 (40%), Positives = 177/304 (58%), Gaps = 4/304 (1%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + + V ELIG+TPL+ L + + AKLEM P S+ DR+G +I D ++G + Sbjct: 2 LIQHVQELIGHTPLMALP-IEVPNHSHIYAKLEMFNPGGSIADRLGAYLIEDGLQRGRVN 60 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKG 124 ++ +IEPT+GNTG+GLA A + I+ +P S E+++++ A G E+V T +G Sbjct: 61 -AKTTIIEPTAGNTGIGLALATQAHHLRTILVVPEKFSMEKQVLMQALGAEIVHTPSEEG 119 Query: 125 MKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGG 184 +KGAI KAE + A N Y+ QF+NPANP +Y T PEI I FV+G G+GG Sbjct: 120 IKGAIRKAEALAATISNSYVPMQFKNPANPAAYYHTLAPEILADMPAPITAFVAGAGSGG 179 Query: 185 TITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVV 244 T G YL+ Q++ K VEP E +IL+GG H+ +GIG FIP + ID+ + Sbjct: 180 TFAGVAAYLQAQDSATKAVVVEP-EGSILNGGPAHAHRTEGIGVEFIPPFFDQVRIDQTL 238 Query: 245 QVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLS 304 ++ +++ R LA GLL+G SSGAA AA+++LA A V IFP ERYLS Sbjct: 239 TIADNDAFAQVRHLARDHGLLIGSSSGAALAASLQLATNLP-ANSHIVTIFPDSSERYLS 297 Query: 305 TVLF 308 ++ Sbjct: 298 QKIY 301 >5B55-A nrPDB Length = 340 Score = 321 bits (824), Expect = 2e-88, Method: Composition-based stats. Identities = 123/323 (38%), Positives = 176/323 (54%), Gaps = 11/323 (3%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 + K + L+G TP++ L +G R+ K E S+KDR+ F + A +K Sbjct: 7 QKKMKYLENLVGKTPMLELIFDYKGEERRIFVKNESYNLTGSIKDRMAFYTLKKAYEKNE 66 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD-P 121 IK G + +E TSGNTG+ + A G+ +II MP MS ER+ ++ +FG +++L Sbjct: 67 IKKGAPI-VEATSGNTGIAFSAMGAILGHPVIIYMPDWMSEERKSLIRSFGAKIILVSRK 125 Query: 122 AKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEI---WKGTGGKIDGFVS 178 G G+I K +E P+ Y+ QF N N + HY G EI K IDGFV+ Sbjct: 126 EGGFLGSIEKTKEFAKNNPDTYLPSQFSNLYNSEAHYYGIGLEIVNEMKSLNLNIDGFVA 185 Query: 179 GIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILS-GGKPGPHKIQGIGAGFIPSVLNV 237 G+GTGGT+ G GK +KE +N K+ +EP+ S LS G K H+I+GI FIP ++ + Sbjct: 186 GVGTGGTVMGIGKRIKENFSNAKICPLEPLNSPTLSTGYKVAKHRIEGISNEFIPDLVKL 245 Query: 238 DLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPS 297 D +D VV V ++I MA++LA K GL VGISSGA A+ L Q + V +FP Sbjct: 246 DKLDNVVSVDDGDAIVMAQKLA-KCGLGVGISSGANFIGALML-QNKLGKDSVIVTVFPD 303 Query: 298 FGERYLSTVLFDATRKEAEAMTF 320 ++YLST D R+E F Sbjct: 304 DNKKYLST---DLMREEKVKEDF 323 >5I7O-A nrPDB Length = 326 Score = 315 bits (808), Expect = 2e-86, Method: Composition-based stats. Identities = 110/321 (34%), Positives = 167/321 (52%), Gaps = 18/321 (5%) Query: 6 AKDVTELIGNTPLVYLNNVAE-------GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAE 58 + + +GNTPLV L ++ G R+ AKLE P S+KDR MI AE Sbjct: 7 YDSLLQALGNTPLVGLQRLSPRWDDGRDGPHVRLWAKLEDRNPTGSIKDRPAVRMIEQAE 66 Query: 59 KKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVL 118 GL++PG ++L EPTSGNTG+ LA A KGY+LI MP + S ERR +L +G +++ Sbjct: 67 ADGLLRPGATIL-EPTSGNTGISLAMAARLKGYRLICVMPENTSVERRQLLELYGAQIIF 125 Query: 119 TDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVS 178 + G A+A A+E+ A P+ ML Q+ NPAN HY TGPE+ +I FV+ Sbjct: 126 SAAEGGSNTAVATAKELAATNPSWVMLYQYGNPANTDSHYCGTGPELLADL-PEITHFVA 184 Query: 179 GIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVD 238 G+GT GT+ G G++L+E ANVK+ EP G + ++ + GF+P + + + Sbjct: 185 GLGTTGTLMGTGRFLREHVANVKIVAAEPRYGE-------GVYALRNMDEGFVPELYDPE 237 Query: 239 LIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAA--AAIKLAQRPENAGKLFVAIFP 296 ++ V + +++ R+L EG+ GIS+GA + + Sbjct: 238 ILTARYSVGAVDAVRRTRELVHTEGIFAGISTGAVLHAALGVGAGALAAGERADIALVVA 297 Query: 297 SFGERYLSTVLFDATRKEAEA 317 G +YLST + + +AE Sbjct: 298 DAGWKYLSTGAYAGSLDDAET 318 >3VSD-A nrPDB Length = 389 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 76/300 (25%), Positives = 142/300 (47%), Gaps = 27/300 (9%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCS-SVKDRIGFSMISDAEKKGLIKPGESVLIEPT 74 TPLV + + RV KLE P S SV DR +IS ++ ++ G S++ + T Sbjct: 97 TPLVR-SRLQLPNGVRVWLKLEWYNPFSLSVADRPAVEIISRLSRR--VEKG-SLVADAT 152 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 134 S N GV L+ A GY+ + +P + +++ G ++++ A + Sbjct: 153 SSNFGVALSAVARLYGYRARVYLPGAAEEFGKLLPRLLGAQVIVDPEA---PSTVHLLPR 209 Query: 135 ILAKTPN-GYM-LQQFENPANPKIHYETTGPEIW---KGTGGKIDGFVSGIGTGGTITGA 189 ++ + N G++ + QF N AN + H T EI+ + G + G +GT G ++ A Sbjct: 210 VMKDSKNEGFVHVNQFYNDANFEAHMRGTAREIFVQSRRGGLALRGVAGSLGTSGHMSAA 269 Query: 190 GKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQ---V 246 YL+ + +++ V+P + + PG +++ +L ++++D V Sbjct: 270 AFYLQSVDPSIRAVLVQPAQGDSI----PGIRRVE-------TGMLWINMLDISYTLAEV 318 Query: 247 SSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 + +E+++ ++A +GL++G S GAA A K A + +V + P G +YLS V Sbjct: 319 TLEEAMEAVVEVARSDGLVIGPSGGAAVKALAKKAAEGDLEPGDYVVVVPDTGFKYLSLV 378 >5X2L-A nrPDB Length = 348 Score = 224 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 22/323 (6%) Query: 8 DVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGE 67 ++ + I TP++ + + + + K E+ + S K R + + L + + Sbjct: 18 NIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPK 77 Query: 68 SVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKG 127 +V + +SGN G L + A +G I +P + +++ + A+G +V +P+ + Sbjct: 78 AV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRE 136 Query: 128 AIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTIT 187 +AK + + G M+ + PA T E+ +D V +G GG + Sbjct: 137 NVAKR---VTEETEGIMVHPNQEPA-VIAGQGTIALEVLNQV-PLVDALVVPVGGGGMLA 191 Query: 188 GAGKYLKEQNANVKLYGVEPVESAILSGGK------PGPHKIQGIGAGFIPSV-LN---- 236 G +K +VK+Y EP + K P + + I G S+ LN Sbjct: 192 GIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPI 251 Query: 237 -VDLIDEVVQVSSDESIDMARQLALKE-GLLVGISSGAAAAAAIKLAQRPENAGKLFVAI 294 DL+D++ V+ DE I A QL + LL+ ++G AA + + + + I Sbjct: 252 IRDLVDDIFTVTEDE-IKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICI 310 Query: 295 FPSFGERYLSTVLFDATRKEAEA 317 S G L++ + K+AE Sbjct: 311 VLSGGNVDLTSSI--TWVKQAER 331 >3L6C-A nrPDB Length = 339 Score = 195 bits (497), Expect = 2e-50, Method: Composition-based stats. Identities = 74/326 (22%), Positives = 138/326 (42%), Gaps = 23/326 (7%) Query: 8 DVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGE 67 ++ + + TP++ + + + + K E+ + S K R + I L + Sbjct: 18 NIQDSVHLTPVLTSSILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPK 77 Query: 68 SVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKG 127 +V + +SGN G L + A +G I +P + +++ + A+G +V ++P+ + Sbjct: 78 AV-VTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRE 136 Query: 128 AIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTIT 187 + A+ I+ +T G ++ + PA T E+ +D V +G GG + Sbjct: 137 NV--AQRIIQET-EGILVHPNQEPA-VIAGQGTIALEVLNQV-PLVDALVVPVGGGGMVA 191 Query: 188 GAGKYLKEQNANVKLYGVEPVESAILSGGK------PGPHKIQGIGAGFIPSV-LN---- 236 G +K +VK+Y EP + K P H + I G S+ LN Sbjct: 192 GIAITIKTLKPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSSIGLNTWPI 251 Query: 237 -VDLIDEVVQVSSDESIDMARQLALKE-GLLVGISSGAAAAAAIKLAQRPENAGKLFVAI 294 DL+D+V V+ DE I A QL + LL+ ++G AA + + + + I Sbjct: 252 IRDLVDDVFTVTEDE-IKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICI 310 Query: 295 FPSFGERYLSTVLFDATRKEAEAMTF 320 S G L+++ + K+AE Sbjct: 311 VLSGGNVDLTSL---SWVKQAERPAP 333 >5KZM-B nrPDB Length = 396 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 76/348 (21%), Positives = 127/348 (36%), Gaps = 55/348 (15%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTS 75 T L N+ + ++ K E + + K A++ G + ++ E + Sbjct: 56 TALTKTRNIVKNTRTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGK----KEIIAETGA 111 Query: 76 GNTGVGLAFTAAAKGYKLIITMPASMSTERRI----ILLAFGVELVLT-DPAKGMKGAIA 130 G GV A A K + M A ER+ + G E++ + +K A Sbjct: 112 GQHGVATALACALLDLKCRVYMGAK-DVERQSPNVFRMKLMGAEVIPVHSGSATLKDACN 170 Query: 131 KAEEILAKTPNG--YM------LQQFENPANPKIHY--ETTGPEIWKGTGGKIDGFVSGI 180 +A + + Y+ F E T ++ G D ++ + Sbjct: 171 EALRDWSANYSKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQMLAKEGRLPDAVIACV 230 Query: 181 GTGGTITGA-GKYLKEQNANVKLYGVEPVESAILSG--GKPGPHKIQGIGAGFI-PSVLN 236 G G G ++ E+ NVKL GVEP I +G G P H GI G P + N Sbjct: 231 GGGSNAIGMFADFIDEK--NVKLIGVEPAGKGIETGEHGAPLKHGKTGIFFGMKAPLMQN 288 Query: 237 VD-LIDEVVQV---------------------------SSDESIDMARQLALKEGLLVGI 268 D I+E + + DE++D + L KEG++ + Sbjct: 289 SDGQIEESYSISAGLDFPSVGPQHAHLLAIGRAKYASATDDEALDAFKLLCKKEGIIPAL 348 Query: 269 SSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLFDATRKEAE 316 S A A A+KLA N +L V G++ + T + D +++ E Sbjct: 349 ESSHALAHALKLAYEDPNKEQLLVVNLSGRGDKDIFT-VHDILKEKGE 395 >1CX9-B nrPDB Length = 397 Score = 132 bits (333), Expect = 2e-31, Method: Composition-based stats. Identities = 69/340 (20%), Positives = 113/340 (33%), Gaps = 58/340 (17%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTS 75 T L N+ G + K E + + K A++ G ++ E + Sbjct: 57 TALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMGK----SEIIAETGA 112 Query: 76 GNTGVGLAFTAAAKGYKLIITMPASMSTERRI----ILLAFGVELVLTDPAKGMKGAIAK 131 G GV A +A G K I M A ER+ + G E++ G Sbjct: 113 GQHGVASALASALLGLKCRIYMGAK-DVERQSPNVFRMRLMGAEVI--PVHSGSATLKDA 169 Query: 132 AEEILAKTPNGYMLQQF--ENPANPKIHY-----------ETTGPEIWKGTGGKIDGFVS 178 E L Y + A P + E T +I G D ++ Sbjct: 170 CNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILDKEGRLPDAVIA 229 Query: 179 GIGTGGTITGA-GKYLKEQNANVKLYGVEPVESAILSG--GKPGPHKIQGIGAGFIPSVL 235 +G G G ++ + +V L GVEP I +G G P H GI G ++ Sbjct: 230 CVGGGSNAIGMFADFI--NDTSVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMM 287 Query: 236 NVD--LIDEVV---------------------------QVSSDESIDMARQLALKEGLLV 266 I+E ++ DE+++ + L EG++ Sbjct: 288 QTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALEAFKTLCRHEGIIP 347 Query: 267 GISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 + S A A A+K+ + +L V G++ + TV Sbjct: 348 ALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTV 387 >5YBW-A nrPDB Length = 329 Score = 116 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 52/285 (18%), Positives = 108/285 (37%), Gaps = 29/285 (10%) Query: 3 SRIAKDVTELIGNTPLVYLNN----VAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAE 58 + +++ I TP+ V + K E ++ S K R + I A Sbjct: 12 KKAYDRISKHILYTPVFTSPTFDRMVGSKAGRQFYFKAENLQKTGSFKARGALNAILCAL 71 Query: 59 KKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVL 118 ++ +P + ++ +SGN G LA+ + G K + +P + + + +G E+V Sbjct: 72 ER---EPSLAGVVTHSSGNHGQALAWASKRAGVKCCVVVPKTAPQVKFDAMENYGAEVVK 128 Query: 119 TDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVS 178 +P + E + Y+ + + T E+ + +D + Sbjct: 129 CEPNPTSRK--ETCEGLAKSRGYKYISS--SDDYDVIAGQGTIALELLQQQPD-LDAILV 183 Query: 179 GIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILS----GGKPGPHKIQ---GIGAGFI 231 + GG +G Y K +++K++ VEP + + P+ Q I G I Sbjct: 184 SVSAGGMASGICVYTKNTKSDLKVFLVEPEGKMLEECISKRERLWPNPPQFLDTIADGII 243 Query: 232 ---------PSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLVG 267 P +L + EV+ V++D ++ R + + L++ Sbjct: 244 LQQCGNKTWPIILELPE-KEVITVNNDNIVEAMRFVFARMKLVIE 287 >5EY5-B nrPDB Length = 399 Score = 114 bits (286), Expect = 5e-26, Method: Composition-based stats. Identities = 73/355 (20%), Positives = 139/355 (39%), Gaps = 71/355 (20%) Query: 8 DVTELIGN-TPLVYLNNVAEGCV-GRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP 65 + + +G TPL + N+ + ++ K E + + K A++ G Sbjct: 42 YLRDYVGRPTPLYFAENLTKDLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGK--- 98 Query: 66 GESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRII----LLAFGVEL-VLTD 120 + V+ E +G GV A AA G + ++ M A ER+ + + G ++ +T Sbjct: 99 -KRVIAETGAGQHGVATATVAAMFGLECVVYMGAE-DIERQALNVFRMKLLGAKVRPVTS 156 Query: 121 PAKGMKGAIAKAEE---------------ILAKTPNGYMLQQFENPANPKIHYETTGPEI 165 ++ +K AI +A ++ P M++ F++ + +I Sbjct: 157 GSRTLKDAINEAMRDWVTNVEDTFYIIGSVVGPHPYPMMVRDFQSVIGEEAR-----QQI 211 Query: 166 WKGTGGKIDGFVSGIGTGGTITGAGK-YLKEQNANVKLYGVEPVESAILSG--------G 216 + G D V+ +G G G ++ ++ +V+L GVE I +G G Sbjct: 212 LEKEGRLPDAIVACVGGGSNAMGIFHPFIDDE--SVRLIGVEAAGKGIETGKHAATLSAG 269 Query: 217 KPGP-------------------HKI------QGIGAGFIPSVLNVDLIDEVVQVSSDES 251 +PG H I G+G + L E V V+ DE+ Sbjct: 270 RPGVLHGAMTYLLQDEDGQIIEAHSISAGLDYPGVGPEH--AYLKDTGRAEYVSVTDDEA 327 Query: 252 IDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 ++ + L+ EG++ + S A A A+KLA + ++ V G++ ++TV Sbjct: 328 LEAFQLLSRTEGIIPALESSHAVAYAMKLAPE-LSKDQIIVVNLSGRGDKDVNTV 381 >5OCW-B nrPDB Length = 442 Score = 108 bits (270), Expect = 3e-24, Method: Composition-based stats. Identities = 74/341 (21%), Positives = 115/341 (33%), Gaps = 60/341 (17%) Query: 16 TPLVYLNNVAEGCVG-RVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPT 74 +PL +++ R+ K E + S K A + G + V+ E Sbjct: 102 SPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALLARRMGKTR----VIAETG 157 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRII----LLAFGVELVLT-DPAKGMKGAI 129 +G GV A A G +I M + T R+ + + G E+V +K +K AI Sbjct: 158 AGQHGVATATACALLGLDCVIYMGG-IDTARQALNVARMRLLGAEVVAVQTGSKTLKDAI 216 Query: 130 AKAEE-ILAKTPNGYM-------LQQFENPANPKIHYETTGPE----IWKGTGGKIDGFV 177 +A +A N Y F P + G E I G D V Sbjct: 217 NEAFRDWVANADNTYYCFGTAAGPHPF--PTMVRDFQRIIGMEARVQIQGQAGRLPDAVV 274 Query: 178 SGIGTGGTITGA-GKYLKEQNANVKLYGVEPVESAILSG--------GKPG--------- 219 + +G G G +L + V+L G E + +G G PG Sbjct: 275 ACVGGGSNAIGIFHAFLD--DPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYL 332 Query: 220 ----------PHKIQ-GIGA-GFIPSVLNVDLIDEV--VQVSSDESIDMARQLALKEGLL 265 H I G+ G P + V ++ E++D L EG++ Sbjct: 333 LQDEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGII 392 Query: 266 VGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTV 306 I S A A A+KL G + V G++ + T Sbjct: 393 PAIESAHAVAGALKLGVE-LGRGAVIVVNLSGRGDKDVETA 432 >6AMI-A nrPDB Length = 396 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 78/347 (22%), Positives = 134/347 (38%), Gaps = 70/347 (20%) Query: 16 TPLVYLNNVAEGCV-GRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKP--GESVLIE 72 TPL Y + E +V K E + + K ++A + L+ G++ LI Sbjct: 51 TPLYYAKRLTEKIGGAKVYLKREDLVHGGAHK-------TNNAIGQALLAKFMGKTRLIA 103 Query: 73 PT-SGNTGVGLAFTAAAKGYKLIITMPASMSTERRII----LLAFGVELVLTD-PAKGMK 126 T +G GV A A G K+ I M A ER+ + + G ++ + ++ +K Sbjct: 104 ETGAGQHGVATAMAGALLGMKVDIYMGAE-DVERQKMNVFRMKLLGANVIPVNSGSRTLK 162 Query: 127 GAIAKAEE---------------ILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGG 171 AI +A ++ P +++ F++ + +I + G Sbjct: 163 DAINEALRDWVATFEYTHYLIGSVVGPHPYPTIVRDFQSVIGREA-----KAQILEAEGQ 217 Query: 172 KIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVE--------SAILSGGKPG-PHK 222 D V+ +G G G Y + VKL GVE SA L+ G+ G H Sbjct: 218 LPDVIVACVGGGSNAMGI-FYPFVNDKKVKLVGVEAGGKGLESGKHSASLNAGQVGVSHG 276 Query: 223 I--------QG-------IGAGF-IPSV------LNVDLIDEVVQVSSDESIDMARQLAL 260 + +G I G P V L E V V+ +E++ +L+ Sbjct: 277 MLSYFLQDEEGQIKPSHSIAPGLDYPGVGPEHAYLKKIQRAEYVAVTDEEALKAFHELSR 336 Query: 261 KEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVL 307 EG++ + S A A A+KLA+ + ++ + G++ L VL Sbjct: 337 TEGIIPALESAHAVAYAMKLAKE-MSRDEIIIVNLSGRGDKDLDIVL 382 >5CVC-A nrPDB Length = 346 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 82/216 (37%), Gaps = 13/216 (6%) Query: 3 SRIAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGL 62 +RIA V TP++ ++ ++ K E + + K R + I A Sbjct: 28 ARIAPYVH----RTPVMSSTSIDAMVGKKLFFKCECFQKAGAFKIRGASNSIF-ALDDEQ 82 Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 + G ++ +SGN +A A +G I +P + + + +G ++ +D + Sbjct: 83 VSKG---VVTHSSGNHAAAVALAAKLRGIPAHIVIPRNAPASKVENVKCYGGHIIWSDAS 139 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGT 182 + ++K + + ++ N T E+ + +ID + I Sbjct: 140 IESREYVSKR---VQEETGAVLIHPI-NSKYTISGQGTVSLELLEQV-PEIDTIIVPISG 194 Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKP 218 GG I+G K N ++++ EP + + K Sbjct: 195 GGLISGVALAAKAINPSIRILAAEPKGADDSAQSKA 230 >1V71-A nrPDB Length = 323 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 61/303 (20%), Positives = 117/303 (38%), Gaps = 26/303 (8%) Query: 15 NTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPT 74 TP++ + V + V V K E + + K R + +S + ++ ++ + Sbjct: 26 KTPVLTSSTVNKEFVAEVFFKCENFQKMGAFKFRGALNALSQLNEAQR----KAGVLTFS 81 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 134 SGN +A +A G I MP + +G ++++ D K + A+E Sbjct: 82 SGNHAQAIALSAKILGIPAKIIMPLDAPEAKVAATKGYGGQVIMYDRYKDDRE--KMAKE 139 Query: 135 ILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLK 194 I + + +++P + T E+++ G +D +G GG ++G+ + Sbjct: 140 ISEREGLTIIP-PYDHP-HVLAGQGTAAKELFEEV-GPLDALFVCLGGGGLLSGSALAAR 196 Query: 195 EQNANVKLYGVEPVESAILS-----GGKPGPHKIQGIGAGFIPSVLN-------VDLIDE 242 N ++YGVEP G + I G L + +D+ Sbjct: 197 HFAPNCEVYGVEPEAGNDGQQSFRKGSIVHIDTPKTIADGAQTQHLGNYTFSIIKEKVDD 256 Query: 243 VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSF---G 299 ++ VS +E ID + A + ++V + + AAA A + + K I Sbjct: 257 ILTVSDEELIDCLKFYAARMKIVVEPTGCLSFAAAR--AMKEKLKNKRIGIIISGGNVDI 314 Query: 300 ERY 302 ERY Sbjct: 315 ERY 317 >6NMX-A nrPDB Length = 354 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 69/315 (21%), Positives = 124/315 (39%), Gaps = 35/315 (11%) Query: 14 GNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEP 73 GNTPL++L ++E + K E + P S KDR ++ A+++G ++++ Sbjct: 29 GNTPLIHLPKLSEQLGIELHVKTEGVNPTGSFKDRGMVMAVAKAKEEG----NDTIMCAS 84 Query: 74 TSGNTGVGLAFTAAAKGYKLIITMP-ASMSTERRIILLAFGVELVLTDPAKGMKGAIAKA 132 T GNT A AA K I+ +P ++ + + +G E++ D A+ Sbjct: 85 T-GNTSAAAAAYAARANMKCIVIIPNGKIAFGKLAQAVMYGAEIIAIDGN--FDDALKIV 141 Query: 133 EEILAKTPNGYMLQQFENPANPK--IHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAG 190 I K+P + N NP +T E+ + G D +G G I+ Sbjct: 142 RSICEKSPIALV-----NSVNPYRLEGQKTAAFEVCEQLGEAPDVLAIPVGNAGNISAYW 196 Query: 191 KYLKEQN-------ANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDL---- 239 K KE + ++ + E + + + P I P+ + + Sbjct: 197 KGFKEYHEKNGTSLPKMRGFEAEGSAAIVRNEVIENPETIATAIRIGNPASWDKAVKAAE 256 Query: 240 -----IDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPE-NAGKLFVA 293 IDE V+ DE + + +A +EG+ S A+ A +K + E G VA Sbjct: 257 ESNGKIDE---VTDDEILHAYQLIAREEGVFAEPGSCASIAGVLKQVKSGEIPKGSKVVA 313 Query: 294 IFPSFGERYLSTVLF 308 + G + +T + Sbjct: 314 VLTGNGLKDPNTAVD 328 >1TDJ-A nrPDB Length = 514 Score = 102 bits (255), Expect = 2e-22, Method: Composition-based stats. Identities = 69/308 (22%), Positives = 119/308 (38%), Gaps = 30/308 (9%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESV-LIEPT 74 TPL + ++ + K E +P S K R ++M+ GL + ++ +I + Sbjct: 32 TPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMM-----AGLTEEQKAHGVITAS 86 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 134 +GN G+AF++A G K +I MP + + + + FG E++L G AKA+ Sbjct: 87 AGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLL----HGANFDEAKAKA 142 Query: 135 ILAKTPNGY-MLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYL 193 I G+ + F++P T E+ + +D +G GG G + Sbjct: 143 IELSQQQGFTWVPPFDHPM-VIAGQGTLALELLQQ-DAHLDRVFVPVGGGGLAAGVAVLI 200 Query: 194 KEQNANVKLYGVEPVESAILSGGKPGPHKI---------QGIGAGFIPS---VLNVDLID 241 K+ +K+ VE +SA L H + +G+ I L + +D Sbjct: 201 KQLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLD 260 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSF--- 298 +++ V SD + L + S A A K G+ I Sbjct: 261 DIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVN 320 Query: 299 --GERYLS 304 G RY+S Sbjct: 321 FHGLRYVS 328 >3IAU-A nrPDB Length = 366 Score = 100 bits (249), Expect = 1e-21, Method: Composition-based stats. Identities = 49/199 (24%), Positives = 82/199 (41%), Gaps = 9/199 (4%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTS 75 +PL +++ K E + S K R ++M+S+ ++ L + +I ++ Sbjct: 61 SPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREEL----DKGVITASA 116 Query: 76 GNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEI 135 GN G+A I MP + + + A G ++VL K A A E+ Sbjct: 117 GNHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLY--GKTFDEAQTHALEL 174 Query: 136 LAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLKE 195 K Y+ F++P K T G EI + I +G GG I G + K+ Sbjct: 175 SEKDGLKYIP-PFDDPGVIKG-QGTIGTEINRQLKD-IHAVFIPVGGGGLIAGVATFFKQ 231 Query: 196 QNANVKLYGVEPVESAILS 214 N K+ GVEP +A ++ Sbjct: 232 IAPNTKIIGVEPYGAASMT 250 >2GN1-A nrPDB Length = 342 Score = 99.6 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 64/268 (23%), Positives = 108/268 (40%), Gaps = 27/268 (10%) Query: 13 IGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFS---MISDAEKKGLIKPGESV 69 I T + N +E C G + K E M+ S K R F+ +++AEK+ G Sbjct: 38 IYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTEAEKR----KG--- 90 Query: 70 LIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAI 129 ++ ++GN G++ + A G + MP + + E+VL I Sbjct: 91 VVACSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVL--HGDNFNDTI 148 Query: 130 AKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGA 189 AK EI+ ++ +++P T G EI + +D + IG GG I G Sbjct: 149 AKVSEIVETEGRIFIP-PYDDP-KVIAGQGTIGLEIMEDLYD-VDNVIVPIGGGGLIAGI 205 Query: 190 GKYLKEQNANVKLYGVEPVE----SAILSGGKPGPHKIQGIGAGFI----PSVLN----V 237 +K N +K+ GV+ +A G+ H+ G A P L Sbjct: 206 AIAIKSINPTIKVIGVQAENVHGMAASYYTGEITTHRTTGTLADGCDVSRPGNLTYEIVR 265 Query: 238 DLIDEVVQVSSDESIDMARQLALKEGLL 265 +L+D++V VS DE + L + ++ Sbjct: 266 ELVDDIVLVSEDEIRNSMIALIQRNKVI 293 >5KIN-B nrPDB Length = 407 Score = 98.8 bits (245), Expect = 3e-21, Method: Composition-based stats. Identities = 65/367 (17%), Positives = 129/367 (35%), Gaps = 68/367 (18%) Query: 11 ELIGN-TPLVYLNNVAEGCV-GRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGES 68 + +G TPL Y N+ + ++ K E + + K + A++ G + Sbjct: 54 QYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGK----KK 109 Query: 69 VLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRII----LLAFGVELV-LTDPAK 123 ++ E +G GV A AA + I M +R+ + + G ++ +TD ++ Sbjct: 110 IIAETGAGQHGVATATAAALFNMECTIYMGEE-DVKRQALNVFRMELLGAKVEAVTDGSR 168 Query: 124 GMKGAIAKAEE-ILAKTPNGYM-------LQQFENPA-NPKIHYETTGPEIWKGTGGK-- 172 +K A+ A +A + + F + + + ++ G+ Sbjct: 169 VLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDLTGRDL 228 Query: 173 IDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFIP 232 D V+ +G G G E + +V +YG E + + H + G P Sbjct: 229 PDALVACVGGGSNAIGLFHPFVE-DESVAMYGTEAAGLGVDT-----EHHAATLTKGR-P 281 Query: 233 SVLNVDLIDEV-------------------------------------VQVSSDESIDMA 255 VL+ L+D + V V+ +E+++ Sbjct: 282 GVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGF 341 Query: 256 RQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLFDATRKEA 315 + L+ EG++ + S A A A+KLA+ K + G++ + V A Sbjct: 342 QLLSRVEGIIPALESSHAIAFAVKLAKE-LGPEKSMIVCLSGRGDKDVVQVKDRLEADAA 400 Query: 316 EAMTFEA 322 + A Sbjct: 401 KKGEAHA 407 >2D1F-A nrPDB Length = 360 Score = 96.5 bits (239), Expect = 2e-20, Method: Composition-based stats. Identities = 68/317 (21%), Positives = 116/317 (36%), Gaps = 25/317 (7%) Query: 9 VTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGES 68 VT L G TPL+ N+++ + K+E + P S KDR ++DA G + Sbjct: 32 VTLLEGGTPLIAATNLSKQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDALAHG-----QR 86 Query: 69 VLIEPTSGNTGVGLAFTAAAKGYKLIITMPA-SMSTERRIILLAFGVELVLTDPAKGMKG 127 ++ ++GNT A AA G + +P ++ + + G +++ D Sbjct: 87 AVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGN--FDD 144 Query: 128 AIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTIT 187 + A ++ A P ++ NP + +T EI G D +G G IT Sbjct: 145 CLELARKMAADFPTISLVNS-VNPVRIEG-QKTAAFEIVDVLGTAPDVHALPVGNAGNIT 202 Query: 188 GAGKYLKE------QNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGFI-PSVLNVDLI 240 K E + ++ G + +A L G+P H A I + Sbjct: 203 AYWKGYTEYHQLGLIDKLPRMLGTQAAGAAPLVLGEPVSHPETIATAIRIGSPASWTSAV 262 Query: 241 D-------EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRP-ENAGKLFV 292 + + S +E + +A EG+ V +S A+ A +K G V Sbjct: 263 EAQQQSKGRFLAASDEEILAAYHLVARVEGVFVEPASAASIAGLLKAIDDGWVARGSTVV 322 Query: 293 AIFPSFGERYLSTVLFD 309 G + T L D Sbjct: 323 CTVTGNGLKDPDTALKD 339 >1VE5-A nrPDB Length = 311 Score = 95.3 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 64/307 (20%), Positives = 116/307 (37%), Gaps = 33/307 (10%) Query: 15 NTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAE-KKGLIKPGESVLIEP 73 TPL+ + R+ K E ++ S K R S E KGL+ Sbjct: 20 RTPLLTSRLLDGLLGKRLLLKAEHLQKTGSFKARGALSKALALENPKGLLA--------V 71 Query: 74 TSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAE 133 +SGN G+A+ A G K ++ MP S ++ A+G E+V + +A+A Sbjct: 72 SSGNHAQGVAYAAQVLGVKALVVMPEDASPYKKACARAYGAEVVDRGVTAKNREEVARA- 130 Query: 134 EILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGK---IDGFVSGIGTGGTITGAG 190 L + ++ F++P T G E+ G ++ +G GG + G Sbjct: 131 --LQEETGYALIHPFDDPL-VIAGQGTAGLELLAQAGRMGVFPGAVLAPVGGGGLLAGLA 187 Query: 191 KYLKEQNANVKLYGVEPVESA----ILSGGKPGPHK---------IQGIGAGFIPSVLNV 237 +K + + GVEP + L G+ + ++ + G + Sbjct: 188 TAVKALSPTTLVLGVEPEAADDAKRSLEAGRILRLEAPPRTRADGVRTLSLGERTFPILR 247 Query: 238 DLIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPS 297 + +D ++ VS + ++ R L + +V + AA ++ R +A+ S Sbjct: 248 ERVDGILTVSEEALLEAERLLFTRTKQVVEPTGALPLAAVLEHGARLPQT----LALLLS 303 Query: 298 FGERYLS 304 G R S Sbjct: 304 GGNRDFS 310 >1PWH-A nrPDB Length = 327 Score = 95.0 bits (235), Expect = 4e-20, Method: Composition-based stats. Identities = 60/308 (19%), Positives = 110/308 (35%), Gaps = 32/308 (10%) Query: 15 NTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPT 74 TPL +++ V K++ +P S K R I K K G + + Sbjct: 10 KTPLRDSMALSKVAGTSVFLKMDSSQPSGSFKIRG----IGHLCKM-KAKQGCKHFVCSS 64 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 134 +GN G+ A+ A G I +P++ L G + + + + AI A+ Sbjct: 65 AGNAGMATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVV--GEMLDEAIQLAKA 122 Query: 135 ILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLK 194 + P + F++P + H + E+ + K V +G GG + G + L+ Sbjct: 123 LEKNNPGWVYISPFDDPLIWEGH-TSLVKELKETLSAKPGAIVLSVGGGGLLCGVVQGLR 181 Query: 195 EQN-ANVKLYGVEPVES-AILSGGKPGP-------------HKIQGIGAGFIPSVLNVDL 239 E +V + +E + + + K G + +GA + + Sbjct: 182 EVGWEDVPIIAMETFGAHSFHAAVKEGKLVTLPKITSVAKALGVNTVGAQTLKLFYEHPI 241 Query: 240 IDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAA-------IKLAQRPENAGKLFV 292 EV +S E++ + E +LV + GAA AA ++ R + V Sbjct: 242 FSEV--ISDQEAVTAIEKFVDDEKILVEPACGAALAAVYSGVVCRLQAEARLQTPLASLV 299 Query: 293 AIFPSFGE 300 I Sbjct: 300 VIVCGGSN 307 >6HUL-B nrPDB Length = 425 Score = 89.6 bits (221), Expect = 2e-18, Method: Composition-based stats. Identities = 69/357 (19%), Positives = 111/357 (31%), Gaps = 61/357 (17%) Query: 12 LIGN-TPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGES 68 IG TPL + E R+ K E P S K A+++G+ E Sbjct: 71 SIGRPTPLFRAKRLEEYLKTPARIYFKYEGATPTGSHKINTAIPQAYFAKEEGI----EH 126 Query: 69 VLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTE----RRIILLAFGV---------- 114 V+ E +G G +A A+ K I M +S E RR I+ +G Sbjct: 127 VVTETGAGQWGTAVALAASMYNMKSTIFM-VKVSYEQKPMRRSIMQLYGANVYASPTNLT 185 Query: 115 ----ELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTG 170 +++ T+P IA +E I N + +H G E Sbjct: 186 EYGRKILETNPQHPGSLGIAMSEAIEYALKNEFRYLVGSVLDVVLLHQSVIGQETITQLD 245 Query: 171 GK---IDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGK--------PG 219 D + +G G G + V E S G+ G Sbjct: 246 LLGEDADILIGCVGGGSNFGGFTYPFIGNKKGKRYIAVSSAEIPKFSKGEYKYDFPDSAG 305 Query: 220 PHKIQ---GIGAGFIPS-----------------VLNVDLIDEVVQVSSDESIDMARQLA 259 + +G ++P +L + I E + + E + A+ Sbjct: 306 LLPLVKMITLGKDYVPPPIYAGGLRYHGVAPTLSLLTKEGIVEWREYNEREIFEAAKIFI 365 Query: 260 LKEGLLVGISSGAAAAAAIKLA--QRPENAGKLFVAIFPSFGERYLSTVLFDATRKE 314 +G++ S A A + A R N K+ V G LS +++ K Sbjct: 366 ENQGIVPAPESAHAIRAVVDEAIEARKNNERKVIVFNLSGHGLLDLSN--YESMMKR 420 >1UIN-A nrPDB Length = 351 Score = 88.8 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 71/320 (22%), Positives = 116/320 (36%), Gaps = 36/320 (11%) Query: 9 VTELIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPG 66 ++ L G+TPL+ L E R+ AK E + P S KDR +S A + G Sbjct: 22 ISLLEGSTPLIPLKGPEEARKKGIRLYAKYEGLNPTGSFKDRGMTLAVSKAVEGG----- 76 Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLA-FGVELVLTDPAKGM 125 + ++GNT A AA G I+ +PA ++ G +V + Sbjct: 77 AQAVACASTGNTAASAAAYAARAGILAIVVLPAGYVALGKVAQSLVHGARIVQVEGN--F 134 Query: 126 KGAIAKAEEILAKTPNGYMLQQFENPANPKIHY----ETTGPEIWKGTGGKIDGFVSGIG 181 A+ +++ P + N NP H +T E+ G +G Sbjct: 135 DDALRLTQKLTEAFPVALV-----NSVNP--HRLEGQKTLAFEVVDELGDAPHYHALPVG 187 Query: 182 TGGTITG--AGKY----LKEQNANVKLYGVEPVESAILSGGKPGPHKIQ-------GIGA 228 G IT G L + ++ G + +A L G+P G A Sbjct: 188 NAGNITAHWMGYKAYHALGKAKRLPRMLGFQAAGAAPLVLGRPVERPETLATAIRIGNPA 247 Query: 229 GFIPSVLNVDLIDEVVQ-VSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRP-EN 286 + +V + V++ V+ +E + R LA +EG+ +S AA A KL + Sbjct: 248 SWQGAVRAKEESGGVIEAVTDEEILFAYRYLAREEGIFCEPASAAAMAGVFKLLREGRLE 307 Query: 287 AGKLFVAIFPSFGERYLSTV 306 V G + +T Sbjct: 308 PESTVVLTLTGHGLKDPATA 327 >4NEG-A nrPDB Length = 400 Score = 88.0 bits (217), Expect = 5e-18, Method: Composition-based stats. Identities = 72/354 (20%), Positives = 122/354 (34%), Gaps = 67/354 (18%) Query: 3 SRIAKDVTELIGN-TPLVYLNNVAEGCV-GRVAAKLEMMEPCSSVKDRIGFSMISDAEKK 60 + + +G TPL + N+ E C ++ K E + + K + I A Sbjct: 49 KELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKIN---NTIGQALLA 105 Query: 61 GLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRII----LLAFGVEL 116 + + V+ E +G GV A A G + +I M R+ + + G ++ Sbjct: 106 VRMGK-KKVVAETGAGQHGVATATVCALLGLECVIFMGEE-DVRRQKLNVFRMELLGAKV 163 Query: 117 VLTDPAKG-MKGAIAKAEEILAK-------TPNGYM-LQQFENPANPKIHYE-------T 160 G +K A+ +A + F P+I + Sbjct: 164 ESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPF-----PQIVRDFQSVIGNE 218 Query: 161 TGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAI-------- 212 T + G + V+ IG G G Y + V LYGVE + Sbjct: 219 TKKQYEALEGKLPEAVVACIGGGSNAMGM-FYPFVHDEEVALYGVEAAGKGVHTEKHAAT 277 Query: 213 LSGGKPG----------------PHKIQGIGAGF-IPSV-LNVDLIDEV-----VQVSSD 249 L+ G G + I AG P V L+ ++ ++ D Sbjct: 278 LTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDD 337 Query: 250 ESIDMARQLALKEGLLVGISSGAAAAAAIKLA-QRPENAGKLFVAIFPSFGERY 302 E+++ + L KEG++ + S A A A+KLA Q E+ G V G++ Sbjct: 338 EALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEG--LVICLSGRGDKD 389 >2ZSJ-A nrPDB Length = 352 Score = 87.6 bits (216), Expect = 6e-18, Method: Composition-based stats. Identities = 69/300 (23%), Positives = 114/300 (38%), Gaps = 33/300 (11%) Query: 14 GNTPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLI 71 GNTPL+ +N+A G G++ K E + P S KDR IS A + G + +I Sbjct: 29 GNTPLIEADNLARAIGFKGKIYLKYEGLNPTGSFKDRGMTLAISKAVEAG-----KRAVI 83 Query: 72 EPTSGNTGVGLAFTAAAKGYKLIITMP-ASMSTERRIILLAFGVELVLTDPAKGMKGAIA 130 ++GNT A AA G + + +P +++ + + +G +++ ++G Sbjct: 84 CASTGNTSASAAAYAARAGLRAYVLLPKGAVAIGKLSQAMIYGAKVL------AIQGTFD 137 Query: 131 KAEEILAKTPNGYMLQQFENPANPK--IHYETTGPEIWKGTGGKIDGFVSGIGTGGTITG 188 A I+ K + + N NP +T EI G D +G G IT Sbjct: 138 DALNIVRKIGENF-PVEIVNSVNPYRIEGQKTAAFEICDTLGEAPDYHFIPVGNAGNITA 196 Query: 189 AGKYLKEQNANVKL------YGVEPVESAILSGGKPGPHKIQGIGAGFIPSV--LNVDLI 240 K K K+ G + +A + G P + Q I + Sbjct: 197 YWKGFKIYYEEGKITKLPRMMGWQAEGAAPIVKGYPIKNP-QTIATAIKIGNPYSWKSAL 255 Query: 241 D-------EVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVA 293 ++ VS E + + +A EG+ +S A+ A IKL + G V Sbjct: 256 KAAQESGGKIDAVSDSEILYAYKLIASTEGVFCEPASAASVAGLIKLVREGFFKGGEVVT 315 >1X1Q-A nrPDB Length = 418 Score = 86.5 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 67/359 (18%), Positives = 118/359 (32%), Gaps = 73/359 (20%) Query: 7 KDVTELIGN-TPLVYLNNVAEG-CVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + + G TPL + ++E +V K E + + K A + G + Sbjct: 68 HYLRQFAGRPTPLYHAKRLSEYWGGAQVFLKREDLLHTGAHKINNTLGQALLARRMGKRR 127 Query: 65 PGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRII-----LLAFGVELVLT 119 V+ E +G GV +A AA G + ++ M RR + G E+ Sbjct: 128 ----VIAETGAGQHGVSVATVAALFGLECVVYMGE--EDVRRQALNVFRMKLLGAEV--R 179 Query: 120 DPAKGMKGAIAKAEEILAK----------TPNGYM-LQQFENPANPKIHYETTGPEIWKG 168 A G + E + + + P + G E+ + Sbjct: 180 PVAAGSRTLKDATNEAIRDWITNVRTTFYILGSVVGPHPY--PMMVRDFQSVIGEEVKRQ 237 Query: 169 ----TGGKIDGFVSGIGTGGTITGA---GKYLKEQNANVKLYGVEPVE--------SAIL 213 G D ++ +G G G YL E KL GVE +A + Sbjct: 238 SLELFGRLPDALIAAVGGGSNAIGLFAPFAYLPEGRP--KLIGVEAAGEGLSTGRHAASI 295 Query: 214 SGGKPGP-------------------HKI------QGIGAGFIPSVLNVDLIDEVVQVSS 248 GK G H + G+G S + E V+ Sbjct: 296 GAGKRGVLHGSYMYLLYDHDGQITPAHSVSAGLDYPGVGPEH--SYYADAGVAEYASVTD 353 Query: 249 DESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVL 307 +E+++ + LA EG++ + S A A A K+ + ++ V G++ ++ V+ Sbjct: 354 EEALEGFKLLARLEGIIPALESAHAIAYAAKVVPE-MDKDQVVVINLSGRGDKDVTEVM 411 >5C3U-A nrPDB Length = 366 Score = 79.6 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 68/334 (20%), Positives = 122/334 (36%), Gaps = 40/334 (11%) Query: 5 IAKDVTELIGNTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIK 64 + D+ L TPL++ N+ + V K+E ++P SVK R + A + Sbjct: 11 LFDDLQSLHVATPLLHAPNLTKELECNVFLKMENIQPSGSVKMRGIGAFCYQAVQ----T 66 Query: 65 PGESVLIEPTSG-NTGVGLAFTAAAKGYKLIITMPASMSTERR-IILLAFGVELVLTDPA 122 G ++ SG NT + +++ A G + II +P + ER + G L+L Sbjct: 67 RGTNIQFVCGSGPNTVLAVSYCARQLGVEAIIVVP-KATNERICQSIRTDGSHLILY--G 123 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSG--- 179 + A A +++ + NG + ++ + H T E+ + Sbjct: 124 ENWTAAEVHARKLVRR--NGIYVPSSDHALIWQGH-STIVQELKTQLNDNPPAAIICPVG 180 Query: 180 --IGTGGTITGAGKYLKEQN-ANVKLYGVEPVES-----AILSGGKPGPHKIQGIGAGFI 231 G I G L+E + +V + VE S ++++G K I I Sbjct: 181 GGGLLNGVIMG----LQEADWKDVPVIAVETHGSNAFQASVVAGELVIMEKNNTIATSLI 236 Query: 232 PSVLNVDLIDEV-------VQVSSDESIDMARQLALKEGLLVGISSGAAA----AAAIKL 280 ++ ++ VS + D R A +LV S+GAA I+ Sbjct: 237 SKAVSSKSLELSLNHPVVPFAVSDAMAADAVRLFAEDFKMLVEASAGAALSLCYTHLIRD 296 Query: 281 AQRPENAGKLFVAIFPSFGERYLSTVLFDATRKE 314 + K V + + +S D RK+ Sbjct: 297 ILPSLSPAKDVVVLVTGGSD--ISLAHLDEYRKK 328 >4H27-A nrPDB Length = 364 Score = 75.3 bits (184), Expect = 4e-14, Method: Composition-based stats. Identities = 59/322 (18%), Positives = 114/322 (35%), Gaps = 34/322 (10%) Query: 15 NTPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPT 74 TP+ +++ V K++ +P S K R I K+ K G + + + Sbjct: 46 KTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRG----IGHFCKR-WAKQGCAHFVCSS 100 Query: 75 SGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEE 134 SGN G+ A+ A G I +P + L G + + + + A A+ Sbjct: 101 SGNAGMAAAYAARQLGVPATIVVPGTTPALTIERLKNEGATVKVV--GELLDEAFELAKA 158 Query: 135 ILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLK 194 + P + F++P + H + E+ + K +G GG + G + L+ Sbjct: 159 LAKNNPGWVYIPPFDDPLIWEGHA-SIVKELKETLWEKPGAIALSVGGGGLLCGVVQGLQ 217 Query: 195 EQN-ANVKLYGVEPVES-AILSGGKPGP-------------HKIQGIGAGFIPSVLNVDL 239 E +V + +E + + + G ++ +GA + + Sbjct: 218 EVGWGDVPVIAMETFGAHSFHAATTAGKLVSLPKITSVAKALGVKTVGAQALKLFQEHPI 277 Query: 240 IDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAA-------IKLAQRPENAGKLFV 292 EV +S E++ + E +LV + GAA AA ++L V Sbjct: 278 FSEV--ISDQEAVAAIEKFVDDEKILVEPACGAALAAVYSHVIQKLQLEGNLRTPLPSLV 335 Query: 293 AIFPSFGERYLSTVLFDATRKE 314 I +S A +++ Sbjct: 336 VIVCGGSN--ISLAQLRALKEQ 355 >6EQN-B nrPDB Length = 425 Score = 72.2 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 65/352 (18%), Positives = 112/352 (31%), Gaps = 76/352 (21%) Query: 13 IGN-TPLVYLNNVAE--GCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESV 69 +G TP++ + E G ++ K+E S K + + A + + V Sbjct: 72 VGRPTPIIRAKRLEEYLGNNIKIYLKMESYTYTGSHKINSALAHVYYA----KLDNAKFV 127 Query: 70 LIEPTSGNTGVGLAFTAAAKGYKLIITMPAS---MSTERRIILLAFGVELVLTDPAK--- 123 E +G G +A +A K I M + R+ ++ +G E V P+ Sbjct: 128 TTETGAGQWGSSVALASALFRMKAHIFMVRTSYYAKPYRKYMMQMYGAE-VHPSPSDLTE 186 Query: 124 -------------GMKG-AIAKAEEILAKTPNGYMLQQFENPANPKIHYET-TGPEIWKG 168 G G AI+ A E K Y++ + N I ++T G E K Sbjct: 187 FGRQLLAKDSNHPGSLGIAISDAVEYAHKNGGKYVV---GSVVNSDIMFKTIAGMEAKKQ 243 Query: 169 T---GGKIDGFVSGIGTGGTITGAG-----KYLKEQNANVKLYGVEPVESAILSGGKPGP 220 G D + +G G L+ K S+ + G Sbjct: 244 MELIGEDPDYIIGVVGGGSNYAALAYPFLGDELRSGKVRRKYIA---SGSSEVPKMTKGV 300 Query: 221 HKIQ--------------GIGAGFIPS-----------------VLNVDLIDEVVQVSSD 249 +K IG+ F+P +L I + S + Sbjct: 301 YKYDYPDTAKLLPMLKMYTIGSDFVPPPVYAGGLRYHGVAPTLSLLISKGIVQARDYSQE 360 Query: 250 ESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRPENAG--KLFVAIFPSFG 299 ES A+ + EG + + A ++A+ + +G K + F G Sbjct: 361 ESFKWAKLFSELEGYIPAPETSHALPILAEIAEEAKKSGERKTVLVSFSGHG 412 >5YGR-A nrPDB Length = 404 Score = 71.1 bits (173), Expect = 6e-13, Method: Composition-based stats. Identities = 47/195 (24%), Positives = 79/195 (40%), Gaps = 25/195 (12%) Query: 49 IGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRII 108 + F+ ++ E K IK + V + T GN G G+A+ A G K ++ MP S R Sbjct: 101 LSFAALNTPEIKEKIK--DCVFVTATDGNHGRGVAWAAEQLGLKAVVYMPKGSSLIRAEN 158 Query: 109 LLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQ-----FEN-PANPKIHYETTG 162 + G E +TD A+ A +A+T +LQ +E P Y T Sbjct: 159 IRHHGAECTITD--LNYDDAVRLAHR-MAQTKGWVLLQDTAWTGYEEIPTWIMQGYMTLA 215 Query: 163 PEIWKGT----GGKIDGFV--SGIGT-GGTITG-AGKYLKEQNANVKLYGVEPVESAILS 214 E ++ + +G+G+ G++ G + ++E N + VEP ++ L Sbjct: 216 VEAYEQLAETNSPLPTHLILQAGVGSFAGSVMGYFVEKMQENIPN--IIVVEPHQANCLY 273 Query: 215 GGKP----GPHKIQG 225 PH + G Sbjct: 274 QSAVMDDGQPHCVTG 288 >1J0B-A nrPDB Length = 325 Score = 65.7 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 59/291 (20%), Positives = 112/291 (38%), Gaps = 23/291 (7%) Query: 16 TPLVYLNNVAEGCVGRVAAK---LEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIE 72 TP+ YL N++ V K L + + K R ++ DA KG + + Sbjct: 22 TPIQYLPNISREIGADVYIKRDDLTGLGIGGN-KIRKLEYLLGDALSKGA---DVVITVG 77 Query: 73 PTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIIL-LAFGVELVLTDPAKG---MKGA 128 N A G I+ + + +L G+E + D MK A Sbjct: 78 AVHSNHAFVTGLAAKKLGLDAILVLRGKEELKGNYLLDKIMGIETRVYDAKDSFELMKYA 137 Query: 129 IAKAEEILAKTPNGYMLQQF-ENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTIT 187 AEE+ + Y++ +P + G EI + K D V G+GGT+ Sbjct: 138 EEIAEELKREGRKPYVIPPGGASPIGTLGYVRAVG-EIATQSEVKFDSIVVAAGSGGTLA 196 Query: 188 GAGKYLKEQNANVKLYGV------EPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID 241 G L N +++ G+ E + S + + K ++ G+ P + + Sbjct: 197 GLSLGLSILNEDIRPVGIAVGRFGEVMTSKLDNLIKEAA-ELLGVKVEVRPELYDYSF-G 254 Query: 242 EVVQVSSDESIDMARQLALKEGLLVGIS-SGAAAAAAIKLAQRPENAGKLF 291 E +++ + + + R++ +EG+++ +G A + LA++ E K+ Sbjct: 255 EYGKITGEVA-QIIRKVGTREGIILDPVYTGKAFYGLVDLARKGELGEKIL 304 >3R0X-A nrPDB Length = 448 Score = 64.9 bits (157), Expect = 4e-11, Method: Composition-based stats. Identities = 65/289 (22%), Positives = 108/289 (37%), Gaps = 51/289 (17%) Query: 42 CSSVKDRIGFS-MISDAEK----KGLIKPGE--SVLIEP--------------TSGNTGV 80 S+K R G +++ AEK GL+ + SVL+ P ++GN G+ Sbjct: 112 SGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGL 171 Query: 81 GLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTP 140 + +A G+K+ + M A ++ L + GV +V + G+ A+ + + P Sbjct: 172 SIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGV--AVEQGRKAAQSDP 229 Query: 141 NGYMLQQFENPANPKIHYETTGPEI---WKGTGGKIDG----FVS-GIGTGGTITGAGKY 192 N + + EN + Y G + + G +D FV G GG G Sbjct: 230 NCFFIDD-ENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFG 288 Query: 193 LK-EQNANVKLYGVEPVESA-ILSGGKPGPH--------------KIQGIGAGFIPSVLN 236 LK NV + EP S +L G G H G+ G + Sbjct: 289 LKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVG 348 Query: 237 VD---LIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQ 282 L+D + + DM LA +EG+ + S+ A A ++ Sbjct: 349 RAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICA 397 >4D9F-A nrPDB Length = 342 Score = 61.8 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 68/310 (21%), Positives = 118/310 (38%), Gaps = 33/310 (10%) Query: 10 TELIGN-TPLVYLNNVAEGCVGRVAAKLEMMEP--CSSVKDRIGFSMISDAEKKGLIKPG 66 E IG TPL YL +++ + K + + P K R +++DA ++ G Sbjct: 26 LEFIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNKLRKLEFLVADA-----LREG 80 Query: 67 ESVLIEPTS--GNTGVGLAFTAAAKGYKLIITM--PASMSTER------RIILLAFGVEL 116 LI + N A AA G + + P + E R++L F ++ Sbjct: 81 ADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQI 140 Query: 117 V----LTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGK 172 LTDP ++ A I A+ Y++ + A + Y + EI + Sbjct: 141 EMCDALTDPDAQLQT---LATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIAQQCEEV 197 Query: 173 I--DGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGAGF 230 + V G+ GT G L+ +V+L GV S K + G Sbjct: 198 VGLSSVVVASGSAGTHAGLAVGLEHLMPDVELIGVTVSRSVAEQKPKVIALQQAIAGQLA 257 Query: 231 IPSVLNVDLIDEV----VQVSSDESIDMARQLALKEGLLVGIS-SGAAAAAAIK-LAQRP 284 + + ++ L D+ V +D ++ + LA EG+L+ +G A A I ++Q+ Sbjct: 258 LTATADIHLWDDYFAPGYGVPNDAGMEAVKLLASLEGVLLDPVYTGKAMAGLIDGISQKR 317 Query: 285 ENAGKLFVAI 294 N + I Sbjct: 318 FNDDGPILFI 327 >3SS9-X nrPDB Length = 442 Score = 61.4 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 66/307 (21%), Positives = 112/307 (36%), Gaps = 54/307 (17%) Query: 26 EGCVGRVAAKLEMMEP-CSSVKDRIGFS-MISDAEK----KGLIKPGE------------ 67 + G++ K + P S+K R G +++ AEK GL+ + Sbjct: 97 QPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQ 156 Query: 68 -----SVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 S+ + T GN G+ + +A G+K+ + M A ++ L + GV +V + Sbjct: 157 FFSQYSIAVGST-GNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQD 215 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEI---WKGTGGKIDG---- 175 G+ A+ + + PN + + EN + Y G + + G +D Sbjct: 216 YGV--AVEEGRKAAQSDPNCFFIDD-ENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPL 272 Query: 176 FVS-GIGTGGTITGAGKYLK-EQNANVKLYGVEPVESA-ILSGGKPGPH----------- 221 FV G GG G LK +V + EP S +L G G H Sbjct: 273 FVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGID 332 Query: 222 ---KIQGIGAGFIPSVLNVD---LIDEVVQVSSDESIDMARQLALKEGLLVGISSGAAAA 275 G+ G + L+D +S DM LA +EG+ + S+ A A Sbjct: 333 NLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA 392 Query: 276 AAIKLAQ 282 ++ Sbjct: 393 GPQRVCA 399 >2RKB-A nrPDB Length = 318 Score = 58.8 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 67/305 (21%), Positives = 111/305 (36%), Gaps = 29/305 (9%) Query: 16 TPLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTS 75 TPL+ +++ V K E ++P S K R + + K G L+ + Sbjct: 8 TPLLESWALSQVAGMPVFLKCENVQPSGSFKIRGIGHFCQE-----MAKKGCRHLVCSSG 62 Query: 76 GNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEI 135 GN G+ A+ A G I +P S S + L G E+ LT K A +A+E+ Sbjct: 63 GNAGIAAAYAARKLGIPATIVLPESTSLQVVQRLQGEGAEVQLT--GKVWDEANLRAQEL 120 Query: 136 LAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGAGKYLKE 195 + F++P K H + E+ V +G GG + G L E Sbjct: 121 AK-RDGWENVPPFDHPLIWKGHA-SLVQELKAVLRTPPGALVLAVGGGGLLAGVVAGLLE 178 Query: 196 QN-ANVKLYGVEPV-----ESAILSGGKPGPHKIQGIGAGFIPSVLNVDLID--EVVQVS 247 +V + +E +AI +G I + + ++ +V ++ Sbjct: 179 VGWQHVPIIAMETHGAHCFNAAITAGKLVTLPDITSVAKSLGAKTVAARALECMQVCKIH 238 Query: 248 SD-----ESIDMARQLALKEGLLVGISSGAAAAAA-----IKLAQRPENAGKL--FVAIF 295 S+ E++ +QL E +LV + GAA AA +L L V I Sbjct: 239 SEVVEDTEAVSAVQQLLDDERMLVEPACGAALAAIYSGLLRRLQAEGCLPPSLTSVVVIV 298 Query: 296 PSFGE 300 Sbjct: 299 CGGNN 303 >4D9G-A nrPDB Length = 398 Score = 58.8 bits (141), Expect = 3e-09, Method: Composition-based stats. Identities = 37/159 (23%), Positives = 56/159 (35%), Gaps = 24/159 (15%) Query: 74 TSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD------------- 120 T GN G G+A+ A G +I MP + ER +L G E ++TD Sbjct: 119 TDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAECIVTDMNYDDTVRLTMQH 178 Query: 121 -PAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKIDGFVSG 179 G + A E K P M Q + A+ + E + G + Sbjct: 179 AQQHGWEVVQDTAWEGYTKIPTWIM-QGYATLADEAV-------EQMREMGVTPTHVLLQ 230 Query: 180 IGTGGTITGAGKYLKEQNA--NVKLYGVEPVESAILSGG 216 G G G YL + + N+ VEP ++ + Sbjct: 231 AGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRS 269 >1RQX-A nrPDB Length = 338 Score = 55.7 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 53/313 (16%), Positives = 99/313 (31%), Gaps = 39/313 (12%) Query: 12 LIGNTPLVYLNNVAEGCVGRV--AAKLEMMEPC---SSVKDRIGFSMISDAEKKGLIKPG 66 G TP+ L +++ G+V AK E K R +I +A +G Sbjct: 12 TFGPTPIQPLARLSKHLGGKVHLYAKREDCNSGLAFGGNKTRKLEYLIPEALAQGC---D 68 Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMS--------TERRIILLAFGVELVL 118 V I N +A AA G K ++ ++ + G ++ L Sbjct: 69 TLVSIGGIQSNQTRQVAAVAAHLGMKCVLVQENWVNYSDAVYDRVGNIQMSRILGADVRL 128 Query: 119 TDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIH------YETTGPEIWKG---T 169 G ++ E ++ + + PA H + E+ Sbjct: 129 VP--DGFDIGFRRSWEDALESVRAAGGKPYAIPAGCSDHPLGGLGFVGFAEEVRAQEAEL 186 Query: 170 GGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSG---GKPGPHKIQGI 226 G K D V TG T G ++ GV+ + + + + Sbjct: 187 GFKFDYVVVCSVTGSTQAGMVVGFAADGRADRVIGVDASAKPAQTREQITRIARQTAEKV 246 Query: 227 GAGFIPSVLNVDLI-DEV-----VQVSSDESIDMARQLALKEGLLVGIS-SGAAAAAAIK 279 G ++ D++ DE + ++ +++ R A EG+L G + I+ Sbjct: 247 GLER--DIMRADVVLDERFAGPEYGLPNEGTLEAIRLCARTEGMLTDPVYEGKSMHGMIE 304 Query: 280 LAQRPENAGKLFV 292 + + E V Sbjct: 305 MVRNGEFPEGSRV 317 >1E5X-A nrPDB Length = 486 Score = 49.9 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 50/294 (17%), Positives = 96/294 (32%), Gaps = 40/294 (13%) Query: 30 GRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAK 89 + K + S KD ++S + +K + ++G+T L+ A+ Sbjct: 147 NDLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASA 206 Query: 90 GYKLIITMPA-SMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQF 148 G I+ +PA +S + + +A G ++ D G + EI A+ P Sbjct: 207 GIPSIVFLPANKISMAQLVQPIANGAFVLSIDTD--FDGCMKLIREITAELPIYL----- 259 Query: 149 ENPANP--KIHYETTGPEIWKGTGGKI-DGFVSGIGTGGTITGAGKYLK--------EQN 197 N N +T EI + ++ D + G G I K K ++ Sbjct: 260 ANSLNSLRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIYAFYKGFKMCQELGLVDRI 319 Query: 198 ANVKLYGVEPVESA---ILSGGKPGPHKIQGIGAGFIPSVL--NVDLIDE---------- 242 ++ + + + K F ++ + ID Sbjct: 320 P--RMVCAQAANANPLYLHYKSGWKDFKPMTASTTFASAIQIGDPVSIDRAVYALKKCNG 377 Query: 243 -VVQVSSDESIDMARQLALKEGLLVGISSGAAAAAAIKLAQRP--ENAGKLFVA 293 V + + +E +D Q A G+ + +G A A KL + + V Sbjct: 378 IVEEATEEELMDAMAQ-ADSTGMFICPHTGVALTALFKLRNQGVIAPTDRTVVV 430 >1J0D-A nrPDB Length = 341 Score = 43.3 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 59/320 (18%), Positives = 103/320 (32%), Gaps = 49/320 (15%) Query: 12 LIGNTPLVYLNNVAE--GCVGRVAAKLEMMEPC---SSVKDRIGFSMISDAEKKGLIKPG 66 G +P+ LN +++ G V AK E R ++ D I G Sbjct: 12 TFGPSPISNLNRLSQHLGSKVNVYAKREDCNSGLAFGGNTLRKLEYIVPD------IVEG 65 Query: 67 ESVLIEPTSG---NTGVGLAFTAAAKGYKLIITMPASMST---ER--------RIILLAF 112 + + G N +A AA G K ++ + E+ + Sbjct: 66 DYTHLVSIGGRQSNQTRMVAALAAKLGKKCVLIQEDWVPIPEAEKDVYNRVGNIELSRIM 125 Query: 113 GVEL-VLTDPAK-GMKGAIAKAEEILAKTPNGYMLQQFENPANPKIH------YETTGPE 164 G ++ V+ D GM+ + A A + L + + PA H + E Sbjct: 126 GADVRVIEDGFDIGMRKSFANALQELEDAGHK----PYPIPAGCSEHKYGGLGFVGFADE 181 Query: 165 IWKG---TGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKP--- 218 + G K D V TG T G + + + ++ ++ + + Sbjct: 182 VINQEVELGIKFDKIVVCCVTGSTTAGILAGMAQYGRQDDVIAIDASFTSEKTKEQTLRI 241 Query: 219 --GPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDESIDMARQLALKEGLLV----GISSGA 272 K+ G+ F L+ V ++ +I+ R A +EG+L S Sbjct: 242 ANNTAKLIGVEHEFKDFTLDTRFAYPCYGVPNEGTIEAIRTCAEQEGVLTDPVYEGKSMQ 301 Query: 273 AAAAAIKLAQRPENAGKLFV 292 A IK A L+V Sbjct: 302 GLIALIKEDYFKPGANVLYV 321 >2VCY-A nrPDB Length = 344 Score = 43.3 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 50 GFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRI-I 108 + M+ D E+ ++PG+SV+ ++ G + AAA G + I + ++ Sbjct: 142 AYRMLMDFEQ---LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDR 198 Query: 109 LLAFGVELVLTDPA 122 L + G E V+T+ Sbjct: 199 LKSLGAEHVITEEE 212 >5K1S-A nrPDB Length = 362 Score = 39.5 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 30/75 (40%), Gaps = 3/75 (4%) Query: 60 KGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLT 119 +G ++ GE+VLI SG G+ A G ++I + S + L G + V+ Sbjct: 178 RGKVRAGETVLITGASGGVGLSSVQLARLDGARVIAV---TSSEAKVQALKEAGADEVIV 234 Query: 120 DPAKGMKGAIAKAEE 134 + K + Sbjct: 235 SRGLDFASDVRKRTQ 249 >4RVS-A nrPDB Length = 329 Score = 37.6 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 3/71 (4%) Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 +K G++VL+ +G G+ L A G ++I T+ + E+ + G ++VL P Sbjct: 140 VKRGDTVLVHAGAGGVGLILTQWATHLGVRVITTV---STAEKAKLSKDAGADVVLDYPE 196 Query: 123 KGMKGAIAKAE 133 + A E Sbjct: 197 DAWQFAGRVRE 207 >3IP1-A nrPDB Length = 404 Score = 35.3 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 30/69 (43%), Gaps = 3/69 (4%) Query: 61 GLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTD 120 G I+PG++V+I G +GLA A K + + S RR + G + V+ Sbjct: 209 GGIRPGDNVVI---LGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDP 265 Query: 121 PAKGMKGAI 129 + A+ Sbjct: 266 TKENFVEAV 274 >4J6F-A nrPDB Length = 382 Score = 34.5 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 41/113 (36%), Gaps = 9/113 (7%) Query: 55 SDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGV 114 ++ + GE+VL+ SG G + A A+G I + +L G Sbjct: 196 ERMLERARLAAGETVLVTGASGGVGSAIIQLARARGAVPIAV----AGPGKEAAMLDIGA 251 Query: 115 ELVLTDPAKGMKGAIAKAE-----EILAKTPNGYMLQQFENPANPKIHYETTG 162 + V+T + A+ A +++A G + P+ Y T G Sbjct: 252 QAVVTRGQGDLAEAVEAASGGRPIDVVADLVGGPLFNDLLKILRPEGRYTTAG 304 >1VB3-A nrPDB Length = 428 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 9/86 (10%) Query: 36 LEMME-PCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGY--- 91 LE+ P + KD G M KP ++ TSG+TG +A A G Sbjct: 96 LELFHGPTLAFKDFGGRFMAQMLTHIAGDKP--VTILTATSGDTGAAVAH--AFYGLPNV 151 Query: 92 KLIITMP-ASMSTERRIILLAFGVEL 116 K++I P +S + + G + Sbjct: 152 KVVILYPRGKISPLQEKLFCTLGGNI 177 >2UUQ-A nrPDB Length = 414 Score = 31.8 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 37/109 (33%), Gaps = 1/109 (0%) Query: 82 LAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPN 141 L +++ P + R+++ F V T K + + E++ A Sbjct: 85 LEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGG 144 Query: 142 GYMLQQFEN-PANPKIHYETTGPEIWKGTGGKIDGFVSGIGTGGTITGA 189 + + F+ P+ HY E W G V+ G TGA Sbjct: 145 DIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGA 193 >4EI8-A nrPDB Length = 389 Score = 31.4 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 51/141 (36%), Gaps = 6/141 (4%) Query: 114 VELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPEIWKGTGGKI 173 +++ T + K+ ++ + P GY L Q N + Y+T E+ + Sbjct: 240 AQVINTPGVLSLAKLELKSNQLDTENPLGY-LTQLGNALEKGVLYDTEREELESAKKSAL 298 Query: 174 DGFVSGIGTG-----GTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGA 228 S + G + +LKE+ V + P + + + K + A Sbjct: 299 SIVTSPLRAGRLYNFSFLNQMENFLKERTPYVDERPIAPYVNKHTTKKEEDIVKFYSVVA 358 Query: 229 GFIPSVLNVDLIDEVVQVSSD 249 G D+IDE+ ++ + Sbjct: 359 GLPLPKRVSDIIDEITRIKEE 379 >3FFK-A nrPDB Length = 377 Score = 31.4 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 15/42 (35%) Query: 272 AAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLFDATRK 313 AA A + + + V++ P GE L F R Sbjct: 308 AALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRD 349 >3FFN-A nrPDB Length = 782 Score = 31.0 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 15/42 (35%) Query: 272 AAAAAAIKLAQRPENAGKLFVAIFPSFGERYLSTVLFDATRK 313 AA A + + + V++ P GE L F R Sbjct: 357 AALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRD 398 >4WAD-A nrPDB Length = 498 Score = 31.0 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 10/56 (17%) Query: 43 SSVKDRIGFSMISDAEKKGLIKPGESV----------LIEPTSGNTGVGLAFTAAA 88 SVKD+I + ++ + G + L+ TS G GL+ A Sbjct: 363 GSVKDKIAKMIEDKNLERNVFLKGYTTTPQKCLEDFKLVVSTSQYEGQGLSMIEAM 418 >2Y4O-A nrPDB Length = 443 Score = 30.6 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 18/33 (54%) Query: 245 QVSSDESIDMARQLALKEGLLVGISSGAAAAAA 277 V+ E +AR+L + +VG+SSG AA Sbjct: 390 SVTDGERAALARELQHRIKTMVGVSSGVTVLAA 422 >1UUF-A nrPDB Length = 369 Score = 30.6 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 25/73 (34%), Gaps = 7/73 (9%) Query: 78 TGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGV-ELVLTDPAKGMKGAIAKAEEIL 136 G+ LA A + + S +R A G E+V + A M + + IL Sbjct: 209 MGIKLAHAMGAH------VVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDFIL 262 Query: 137 AKTPNGYMLQQFE 149 + L F Sbjct: 263 NTVAAPHNLDDFT 275 >3SKY-A nrPDB Length = 274 Score = 30.6 bits (68), Expect = 0.96, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 46/118 (38%), Gaps = 18/118 (15%) Query: 37 EMMEPCSSVKDR----IGFSMISDAEKKGL-IKPGESVLIEPTSGNTGVGLAFTAAAKGY 91 E+++ +S++ R I +++ +AEK+G + E P G G+ G Sbjct: 43 ELLQIAASLEARSEHPIAAAIVEEAEKRGFGLTEVEEFRAIPGKGVEGI-------VNGR 95 Query: 92 KLIITMPASM------STERRIILLAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGY 143 + ++ P + + E L G +V + G IA A+ I ++ Sbjct: 96 RYMVVSPGYIRELGIKTDESVEKLKQQGKTVVFILKNGEVSGVIALADRIRPESREAI 153 >3QWB-A nrPDB Length = 334 Score = 30.6 bits (68), Expect = 0.97, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 42/115 (36%), Gaps = 13/115 (11%) Query: 17 PLVYLNNVAEGCVGRVAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSG 76 P++ L ++ A ++ S ++A +K G+ VL+ +G Sbjct: 110 PVMKLPKGTSDEELKLYA-------AGLLQVLTALSFTNEAYH---VKKGDYVLLFAAAG 159 Query: 77 NTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMKGAIAK 131 G+ L KG I + + E+ I +G E ++ + + + K Sbjct: 160 GVGLILNQLLKMKGAHTIAV---ASTDEKLKIAKEYGAEYLINASKEDILRQVLK 211 >3BKX-A nrPDB Length = 275 Score = 30.6 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 29/86 (33%), Gaps = 13/86 (15%) Query: 164 EIWKGTGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKI 223 EI G G +G+ G +TG P A L+ G+ H + Sbjct: 49 EIGCGQGDLSAVLADQVGSSGHVTGIDI-------------ASPDYGAPLTLGQAWNHLL 95 Query: 224 QGIGAGFIPSVLNVDLIDEVVQVSSD 249 G + N +L D++ ++ Sbjct: 96 AGPLGDRLTVHFNTNLSDDLGPIADQ 121 >1YB5-A nrPDB Length = 351 Score = 30.2 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 39/93 (41%), Gaps = 16/93 (17%) Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 +K GESVL+ SG G+ A A G K++ + TE G ++VL + A Sbjct: 168 VKAGESVLVHGASGGVGLAACQIARAYGLKIL----GTAGTEE-------GQKIVLQNGA 216 Query: 123 KGMKGA-----IAKAEEILAKTPNGYMLQQFEN 150 + I K ++ + + +++ N Sbjct: 217 HEVFNHREVNYIDKIKKYVGEKGIDIIIEMLAN 249 >5W8S-A nrPDB Length = 382 Score = 29.9 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 3/33 (9%) Query: 175 GFVSGIGTGGTITGAG--KYLKEQNANVKLYGV 205 V+G T G I GAG + LKE N + GV Sbjct: 10 ALVAGE-TSGDILGAGLIRALKEHVPNARFVGV 41 >4TLZ-A nrPDB Length = 443 Score = 29.9 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 12/101 (11%), Positives = 33/101 (32%), Gaps = 23/101 (22%) Query: 164 EIWKGTGGKIDGF----------VSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAIL 213 E + +D F V+ G G + ++L + + ++ + P ++ Sbjct: 197 EFVWHSSRFLDHFRDRDPRSLRRVAVAGGGQSAAEIVRFLHDNRPDTVVHAIMPSYGYVV 256 Query: 214 SGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVS--SDESI 252 + P F + + +D+ S + ++ Sbjct: 257 ADNTP-----------FANQIFDPAAVDDYFDGSKQAKDAF 286 >3GFB-A nrPDB Length = 350 Score = 29.9 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 20/102 (19%) Query: 32 VAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVLIEPTSGN----TG------VG 81 V AK P KD A ++ L ++VL P +G TG +G Sbjct: 131 VPAKNAWKNP----KDMPPEYA---ALQEPLGNAVDTVLAGPIAGRSTLITGAGPLGLLG 183 Query: 82 LAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAK 123 +A A+ Y +I++ P S RR + G + V+ + Sbjct: 184 IAVAKASGAYPVIVSEP---SEFRRKLAKKVGADYVVNPFEE 222 >3NAV-A nrPDB Length = 271 Score = 29.9 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 29/85 (34%), Gaps = 2/85 (2%) Query: 67 ESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPAKGMK 126 +SVLI N A G + I P + S E + G G+ Sbjct: 127 DSVLIADVPTNESQPFVAAAEKFGIQPIFIAPPTASDETLRAVAQLGKGYTYLLSRAGVT 186 Query: 127 GAIAKAEEILAKTPNGYMLQQFENP 151 GA KA + LQQF+ P Sbjct: 187 GAETKANMPVHALLER--LQQFDAP 209 >3RLI-A nrPDB Length = 270 Score = 29.5 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 10/68 (14%) Query: 174 DGFVSGIGTGGTITGAGKYLKEQNANVKLY-----GVE-PVESAILSGGKPGPHKIQGIG 227 FV+G+ GGT+T YL E + ++ V+ P +A ++GG P + IG Sbjct: 110 TIFVTGLSMGGTLT---LYLAEHHPDICGIVPINAAVDIPAIAAGMTGGGELPRYLDSIG 166 Query: 228 AGFI-PSV 234 + P V Sbjct: 167 SDLKNPDV 174 >3KW3-A nrPDB Length = 376 Score = 29.5 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 26/88 (29%), Gaps = 9/88 (10%) Query: 169 TGGKIDGFVSGIGTGGTITGAGKYLKEQNANVKLYGVEPVESAILSGGKPGPHKIQGIGA 228 VS +GG G+ Y + LYGV+P + Q Sbjct: 202 LAQLPTCKVSFANSGGIFLGSDFYFDLVRPGIALYGVDPHGKHPTPLKAVVKVEAQ---- 257 Query: 229 GFIPSVLNVDLIDEVVQVSSDESIDMAR 256 VL ID + V ES R Sbjct: 258 -----VLQSRFIDAGIPVGYRESFMTRR 280 >3CJR-A nrPDB Length = 254 Score = 29.1 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 25/54 (46%) Query: 204 GVEPVESAILSGGKPGPHKIQGIGAGFIPSVLNVDLIDEVVQVSSDESIDMARQ 257 ++P+ + GG G + +G F P+ +++ +V ++ ++ R+ Sbjct: 12 ALDPILPGLFDGGARGLWEREGEVWAFFPAPVDLPYEGVWEEVGDEDWLEAWRR 65 >4V75-AD nrPDB Length = 206 Score = 29.1 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 36/110 (32%), Gaps = 9/110 (8%) Query: 85 TAAAKGYKLIITMPASMSTERRIILLAFGVE--LVLTDPAKGMKG------AIAKAEEIL 136 A G KL ++ + + A + + G + + E+ Sbjct: 1 MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQK 60 Query: 137 AKTPNGYMLQQFENPANPKIHYET-TGPEIWKGTGGKIDGFVSGIGTGGT 185 + G + +QF N + TG + G++D V +G G T Sbjct: 61 VRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGAT 110 >4ZGV-A nrPDB Length = 868 Score = 29.1 bits (64), Expect = 3.0, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 21/55 (38%), Gaps = 4/55 (7%) Query: 110 LAFGVELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQQFENPANPKIHYETTGPE 164 + G++++ + K M E+L PN QF N A+ PE Sbjct: 65 QSMGMQIINAEQIKKMPTGNGSVTELLKNNPNV----QFSNTASSSNIPGELAPE 115 >3SLK-A nrPDB Length = 795 Score = 28.7 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 32/86 (37%), Gaps = 24/86 (27%) Query: 63 IKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVELVLTDPA 122 ++PGES+L+ +G GVG+A + G E+ T Sbjct: 343 LRPGESLLVHSAAG--GVGMAAI---------------------QLARHLGAEVYATASE 379 Query: 123 KGMKGAIAKAEEILAKTPNGYMLQQF 148 + A+ + E LA + QQF Sbjct: 380 DKWQ-AVELSREHLASSRTCDFEQQF 404 >5VJ1-D nrPDB Length = 287 Score = 28.7 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 16/35 (45%), Gaps = 4/35 (11%) Query: 258 LALKEGLLVGIS----SGAAAAAAIKLAQRPENAG 288 LA EG G S SGA A A++LA G Sbjct: 73 LAAIEGAFQGGSLGEVSGAKIAGALELAAEDNRNG 107 >2FZ4-A nrPDB Length = 237 Score = 27.9 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 34/93 (36%), Gaps = 7/93 (7%) Query: 55 SDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTER-RIILLAFG 113 A ++ L+ +++ SG T V +A +I +P E+ + L FG Sbjct: 99 EKALERWLVDKRGCIVLPTGSGKTHVAMAAINELS-TPTLIVVPTLALAEQWKERLGIFG 157 Query: 114 VELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQ 146 E V G I + + + T + + Sbjct: 158 EEYV-----GEFSGRIKELKPLTVSTYDSAYVN 185 >1PFK-A nrPDB Length = 320 Score = 27.9 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 12/89 (13%), Positives = 35/89 (39%), Gaps = 10/89 (11%) Query: 183 GGTITGAGKYLKEQNANVKLYGVEPVESAIL--------SGGKPGPHKIQGIGAGFI--P 232 GGT G+ ++ + ++ N++ +E ++ + G G ++ +G I P Sbjct: 65 GGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLP 124 Query: 233 SVLNVDLIDEVVQVSSDESIDMARQLALK 261 ++ D+ + ++ + + Sbjct: 125 GTIDNDIKGTDYTIGFFTALSTVVEAIDR 153 >2E18-A nrPDB Length = 257 Score = 27.9 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 19/40 (47%) Query: 263 GLLVGISSGAAAAAAIKLAQRPENAGKLFVAIFPSFGERY 302 G+++GIS G +A LA + K+ I P F + Sbjct: 24 GVVIGISGGVDSATVAYLATKALGKEKVLGLIMPYFENKD 63 >2FWR-A nrPDB Length = 472 Score = 27.9 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 34/93 (36%), Gaps = 7/93 (7%) Query: 55 SDAEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTER-RIILLAFG 113 A ++ L+ +++ SG T V +A +I +P E+ + L FG Sbjct: 99 EKALERWLVDKRGCIVLPTGSGKTHVAMAAINELS-TPTLIVVPTLALAEQWKERLGIFG 157 Query: 114 VELVLTDPAKGMKGAIAKAEEILAKTPNGYMLQ 146 E V G I + + + T + + Sbjct: 158 EEYV-----GEFSGRIKELKPLTVSTYDSAYVN 185 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.151 0.428 Lambda K H 0.267 0.0463 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,890,458 Number of Sequences: 36641 Number of extensions: 637960 Number of successful extensions: 2139 Number of sequences better than 10.0: 109 Number of HSP's better than 10.0 without gapping: 134 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 1691 Number of HSP's gapped (non-prelim): 207 length of query: 322 length of database: 10,336,785 effective HSP length: 97 effective length of query: 225 effective length of database: 6,782,608 effective search space: 1526086800 effective search space used: 1526086800 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 60 (27.5 bits)