BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P47897 (775 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4R3Z-C nrPDB 1617 0.0 4H3S-A nrPDB 528 e-150 5BNZ-A nrPDB 461 e-130 2RD2-A nrPDB 434 e-122 5ZDO-A nrPDB 402 e-112 4P2B-A nrPDB 401 e-112 2HZ7-A nrPDB 353 1e-97 3AII-A nrPDB 159 6e-39 3TL4-X nrPDB 79 7e-15 2CFO-A nrPDB 71 2e-12 6B1P-A nrPDB 66 6e-11 2JA2-A nrPDB 65 8e-11 4G6Z-A nrPDB 65 1e-10 4GRI-A nrPDB 62 1e-09 2O5R-A nrPDB 62 1e-09 6BRL-A nrPDB 61 2e-09 5TGT-A nrPDB 57 3e-08 2CV2-A nrPDB 54 2e-07 3AL0-C nrPDB 53 4e-07 3AKZ-B nrPDB 53 4e-07 5H4V-A nrPDB 52 7e-07 4A91-A nrPDB 38 0.014 1AYE-A nrPDB 31 1.8 3AEO-A nrPDB 31 1.9 1YXA-A nrPDB 30 3.6 1DTD-A nrPDB 30 4.1 3NYZ-A nrPDB 30 4.3 3UD6-A nrPDB 30 4.5 3TC6-A nrPDB 29 7.9 2C3Z-A nrPDB 29 9.0 3HOJ-A nrPDB 29 9.1 4PEK-A nrPDB 29 9.6 4IJB-A nrPDB 29 9.7 >4R3Z-C nrPDB Length = 799 Score = 1617 bits (4186), Expect = 0.0, Method: Compositional matrix adjust. Identities = 775/775 (100%), Positives = 775/775 (100%) Query: 1 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 60 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA Sbjct: 25 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 84 Query: 61 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 120 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE Sbjct: 85 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 144 Query: 121 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 180 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK Sbjct: 145 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 204 Query: 181 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 240 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT Sbjct: 205 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 264 Query: 241 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 300 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL Sbjct: 265 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 324 Query: 301 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 360 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ Sbjct: 325 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 384 Query: 361 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 420 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV Sbjct: 385 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 444 Query: 421 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 480 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV Sbjct: 445 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 504 Query: 481 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 540 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG Sbjct: 505 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 564 Query: 541 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 600 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET Sbjct: 565 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 624 Query: 601 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 660 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES Sbjct: 625 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 684 Query: 661 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 720 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL Sbjct: 685 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 744 Query: 721 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 775 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV Sbjct: 745 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 799 >4H3S-A nrPDB Length = 817 Score = 528 bits (1359), Expect = e-150, Method: Compositional matrix adjust. Identities = 319/829 (38%), Positives = 452/829 (54%), Gaps = 75/829 (9%) Query: 1 MAALDSLS-LFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGL 59 M++++ L+ LF+ +G ++K +E +KN +S L + + +K+T L++ L Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDY--QWNKSTRALVHNL 58 Query: 60 ASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIV 117 AS ++ D + +V+ I + + T Q+ AA +YV+++ + + GVG+ + Sbjct: 59 ASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANG-EASTKMGMNENSGVGIEI 117 Query: 118 TPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMG-EARAVLKWADGKMIKNEVDMQVLHL 176 T +Q+ V I ++ ++L ERY G+ + LKWAD + K +D +VL L Sbjct: 118 TEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKL 177 Query: 177 LGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGE 236 LGPK E DL K E+ +AK +N ++ ++ + G HK GE Sbjct: 178 LGPKDERDL---IKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNE--GFLGDLHKVGE 232 Query: 237 NYKTPGYVVTPHTM-NLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANN 295 N P L+K+HLE+TGG+VRTRFPPEPNG LHIGH+KAI NFGYAK +N Sbjct: 233 N---------PQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHN 283 Query: 296 GICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLA 355 G C+LRFDDTNPEKE ++F +I MV+WLG+ P+K+TY+SDYFD+LY A LI+ G A Sbjct: 284 GTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKA 343 Query: 356 YVCHQRGEELK-----------GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRM 404 YVCH EE+K G RD+ +E++L F MR GK+ GEA LRM Sbjct: 344 YVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRM 403 Query: 405 KLVMEDGK---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQ 461 K + D +AYRV PH RTG KW IYPTYD+THCL DS+E+ITHSLCT EF Sbjct: 404 KQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFY 463 Query: 462 ARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTA 521 R SY WLC+ + V+ P Q EYGRLN+ V+SKRKI QLV VR WDDPRLFTL A Sbjct: 464 LSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEA 523 Query: 522 LRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITN 581 +RRRG PP AI +F +GVT + T ++ E+ VR L DT PR M VL+ + V++ N Sbjct: 524 IRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDN 583 Query: 582 FPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEE-PEPGFKRLAWGQPVGLRH 640 +P P G VPF +IER+DF E + F RL QPVGL Sbjct: 584 LSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIK 643 Query: 641 TGYVIELQHVVKGPSGCVESLEVT----CRRADAGEKPKAFIHWV------SQPL-MCEV 689 + + + + K +G + + V +KPK +I WV + PL + E Sbjct: 644 VSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTET 703 Query: 690 RLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVA---------------- 733 R+Y +LF+ +N P+ P GFL D+N S V ++++ + Sbjct: 704 RVYNQLFKSEN---PSSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNS 760 Query: 734 --------LAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGK 774 +K +FQ R+GYF++D +S K++ NR V+LK+ K Sbjct: 761 EFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSKVILNRIVSLKDATSK 809 >5BNZ-A nrPDB Length = 564 Score = 461 bits (1187), Expect = e-130, Method: Compositional matrix adjust. Identities = 254/531 (47%), Positives = 332/531 (62%), Gaps = 22/531 (4%) Query: 263 QVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMV 322 ++ TRFPPEPNG LHIGHAK+I NFG A+ G C LRFDDTNP KE+ ++ AI + Sbjct: 36 KIVTRFPPEPNGYLHIGHAKSICLNFGLAQEFAGDCHLRFDDTNPAKEDQEYIDAIEADI 95 Query: 323 AWLGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELK---GHNTLP---SPW 375 WLG+ +V YAS+YFDQL+AWAVELI+ G A+VC EE++ G T P SP+ Sbjct: 96 KWLGFQWSGEVCYASNYFDQLHAWAVELIKAGKAFVCDLGPEEMREYRGTLTEPGRNSPY 155 Query: 376 RDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM---DPVAYRVKYTPHHRTGDKW 432 RDR +EE+L LF M+ G+F +G +LR K+ M M DP+ YR+++ HH+TGDKW Sbjct: 156 RDRSVEENLDLFARMKAGEFPDGARSLRAKIDMGSPNMNLRDPILYRIRHAHHHQTGDKW 215 Query: 433 CIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYC-PVQWEYGRLNLHY 491 CIYP+YD+TH D+IE ITHS+CT EF+ R Y W L V P Q+E+ RLNL+Y Sbjct: 216 CIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLYEWFLANLPVPAQPRQYEFSRLNLNY 275 Query: 492 AVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPH 551 V SKRK+ QLV G V WDDPR+ TL+ RRRG+ PE+I NFC +GV A ++ Sbjct: 276 TVTSKRKLKQLVDEGHVSGWDDPRMSTLSGYRRRGYTPESIRNFCEMIGVNRASGVVDIG 335 Query: 552 LLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPI 611 +LE +RD L+ TAPRAM VL+ L+V+ITN+P + ++++P P E G +PF Sbjct: 336 MLEFSIRDHLDATAPRAMCVLKPLKVVITNYPEGQVENLELPRHPK-EDMGVRVLPFGRE 394 Query: 612 VFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEV-----TCR 666 +FI+ DF+E P G+KRL G V LR + YVI +K G + L T Sbjct: 395 LFIDAGDFEEVPPAGYKRLIPGGEVRLRGS-YVIRADEAIKDADGNIVELRCSYDPDTLG 453 Query: 667 RADAGEKPKAFIHWV--SQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVD 724 + G K K IHWV + CEVRLY+RLF+ NPE E G FL ++N SL V+ Sbjct: 454 KNPEGRKVKGVIHWVPAEGSVECEVRLYDRLFRSANPEK-AEEGGSFLDNINADSLQVLA 512 Query: 725 AALVDCSVALAKPFDKFQFERLGYFSVD-PDSHQGKLVFNRTVTLKEDPGK 774 + S+ A P D+FQFER GYF D DS GK VFNRTVTL++ G+ Sbjct: 513 GCRAEPSLGQANPEDRFQFEREGYFVADLKDSRPGKPVFNRTVTLRDSWGQ 563 >2RD2-A nrPDB Length = 556 Score = 434 bits (1117), Expect = e-122, Method: Compositional matrix adjust. Identities = 243/527 (46%), Positives = 324/527 (61%), Gaps = 27/527 (5%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 V TRFPPEPNG LHIGHAK+I NFG A+ G C LRFDDTNP KE+ ++ +I + V Sbjct: 28 VHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVE 87 Query: 324 WLGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYV---CHQRGEELKGHNTLP---SPWR 376 WLG+ V Y+SDYFDQL+A+A+ELI +GLAYV ++ E +G T P SP+R Sbjct: 88 WLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYR 147 Query: 377 DRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM---DPVAYRVKYTPHHRTGDKWC 433 DR +EE+L LFE MR G F EG+A LR K+ M + DPV YR+K+ HH+TG+KWC Sbjct: 148 DRSVEENLALFEKMRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWC 207 Query: 434 IYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYC-PVQWEYGRLNLHYA 492 IYP YD+THC+ D++E ITHSL T EFQ R Y W+ + + + P Q+E+ RLNL Y Sbjct: 208 IYPMYDFTHCISDALEGITHSLRTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYT 267 Query: 493 VVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHL 552 V+SKRK+ LV V WDDPR+ T++ LRRRG+ +I FC R+GVT T+E Sbjct: 268 VMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMAS 327 Query: 553 LEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIV 612 LE+C+R+ LN+ APRAMAV++ ++++I N+ + + +PN P G QVPF+ + Sbjct: 328 LESCIREDLNENAPRAMAVIDPVKLVIENYQGEGEM-VTMPNHPNKPEMGSRQVPFSGEI 386 Query: 613 FIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSG------CVESLEVTCR 666 +I+R DF+EE +KRL G+ V LR+ YVI+ + V K G C + + Sbjct: 387 WIDRADFREEANKQYKRLVLGKEVRLRN-AYVIKAERVEKDAEGNITTIFCTYDADTLSK 445 Query: 667 RADAGEKPKAFIHWVS--QPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVD 724 G K K IHWVS L E+RLY+RLF NP + FLS +N SL V+ Sbjct: 446 DPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADD----FLSVINPESL-VIK 500 Query: 725 AALVDCSVALAKPFDKFQFERLGYFSVDP-DSHQGKLVFNRTVTLKE 770 + S+ A FQFER GYF +D S K VFNRTV L++ Sbjct: 501 QGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRD 547 >5ZDO-A nrPDB Length = 548 Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust. Identities = 245/528 (46%), Positives = 320/528 (60%), Gaps = 33/528 (6%) Query: 266 TRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWL 325 TRFPPEPNG LHIGHA++I NFG A+ G C LRFDDTNPE E+ ++ AI + V WL Sbjct: 27 TRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEEYARAIEEDVRWL 86 Query: 326 GYTPYKVTYASDYFDQLYAWAVELIRRGLAYV---CHQRGEELKGHNTLPSPWRDRPMEE 382 G+ P +V YASDYF+ +Y A+ LI+ G AYV + EL+ PSP+R+R +EE Sbjct: 87 GFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSELRAQGK-PSPYRERSVEE 145 Query: 383 SLLLFEAMRKGKFSEGEATLRMKL--VMEDGKM-DPVAYRVKYTPHHRTGDKWCIYPTYD 439 +L LFE MR+G+F G LR K+ + K+ DPV YR+ + PH+ GD+W IYP YD Sbjct: 146 NLELFERMRRGEFPTGSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYHVGDRWVIYPMYD 205 Query: 440 YTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYC-------PVQWEYGRLNLHYA 492 + H L D IE +THSLCT EF+ R+ Y W+ L C P Q+E+ RL+L + Sbjct: 206 FAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENLKGKCGLPTSPRPHQYEFARLDLSHT 265 Query: 493 VVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHL 552 V+SKRK+++LV G V WDDPRL TL LRRRG PEAI F + G++ + +E L Sbjct: 266 VLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTGISRNEAQIEMDL 325 Query: 553 LEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETK-GFHQVPFAPI 611 E VRD LN APR + V++ L+V++TN+ + I+ P +P D K G +PF+P Sbjct: 326 FEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEW--IEAPYWPRDIPKEGTRPLPFSPE 383 Query: 612 VFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTC------ 665 ++IERTDF P G+KRLA GQ V LRH YVIEL+ VV+ G V L+ Sbjct: 384 LYIERTDFSLNPPKGWKRLAPGQRVRLRH-AYVIELEDVVEE-GGEVRLLKARIVPGTLG 441 Query: 666 RRADAGEKPKAFIHWVS--QPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVV 723 + G +PK IHWVS L E RLY RLF+ K+PE+ G FL +LN +L VV Sbjct: 442 ANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPEE----GGDFLQNLNPEAL-VV 496 Query: 724 DAALVDCSVALAKPFDKFQFERLGYFSVDP-DSHQGKLVFNRTVTLKE 770 ++ SVA ++Q ERLGYF DP DS LV NR V LKE Sbjct: 497 KRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIVPLKE 544 >4P2B-A nrPDB Length = 576 Score = 401 bits (1030), Expect = e-112, Method: Compositional matrix adjust. Identities = 245/560 (43%), Positives = 321/560 (57%), Gaps = 41/560 (7%) Query: 248 HTMNLLKQHLE---ITGGQ--VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRF 302 H +N LKQ +E TG V TRFPPEPNG LH+GHAK++ NFG AKA G C LRF Sbjct: 20 HMVNFLKQIVEEDLRTGKHKTVITRFPPEPNGFLHLGHAKSVCLNFGLAKAFGGRCHLRF 79 Query: 303 DDTNPEKEEAKFFTAICDMVAWLGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQR 361 DDTNP KEE ++ +I V WLG + YASDYF QLY WA LI++GLA+V Sbjct: 80 DDTNPMKEETRYIESIQRDVRWLGGDWGNHLYYASDYFQQLYDWAELLIKKGLAFVDDDS 139 Query: 362 GEELK---GHNTLP---SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM-- 413 EE++ G + P SP+R+R +EE+L LF MR G+F EG LR K+ M M Sbjct: 140 LEEIRRKRGSISQPGENSPFRERSIEENLDLFRRMRAGEFEEGSRVLRAKIDMTHSNMNM 199 Query: 414 -DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCN 472 DPV YR+ H RTG++W IYP YDY H DSIE+ITHS+CT EF R Y W Sbjct: 200 RDPVLYRILKKEHPRTGNQWVIYPMYDYAHGQSDSIENITHSICTLEFDLHRILYDWFQE 259 Query: 473 ALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAI 532 L++ Q E+ RLN+ Y V+SKRK+L LV V WDDPRL TL+ LRRRG PP A+ Sbjct: 260 KLEITRTRQIEFARLNVTYTVMSKRKLLALVTEKWVDGWDDPRLPTLSGLRRRGVPPSAL 319 Query: 533 NNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQV 592 +FC +VGV ++T++ +LE C+RD L+ A R A+ + + V ITN+ K I Sbjct: 320 RDFCDKVGVARRESTIKVEVLEKCIRDALHVVAHRRFAIQDPIAVTITNY-GDKVETITA 378 Query: 593 PNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVK 652 N P DE+ G ++ F+ ++I+R DF E P G++RLA G V L+H Y I+ VVK Sbjct: 379 ANHPEDESFGTRELHFSKKLYIDRDDFMENPPAGYRRLAPGAEVRLKH-AYWIKCVDVVK 437 Query: 653 GPSGCVESLEVT-------CRRADAGEKPKAFIHWVSQ--PLMCEVRLYERLFQHKNP-- 701 SG V L T C A G K K IHW+S+ + E+R++ RLF NP Sbjct: 438 DASGLVTELLCTYDPQTKNCSVAPDGRKVKGAIHWLSEKDAVPAEIRIFGRLFTKPNPEE 497 Query: 702 EDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPF---DKFQFERLGYFSVD------ 752 ED + + ++N SL V V+ S A + F QFERLG+F+ D Sbjct: 498 EDESNPNASWRENINKESLKVY-KGFVERSAADSAAFPPQSSLQFERLGFFTPDGSTLPE 556 Query: 753 -PDSHQGKL--VFNRTVTLK 769 D+ + + VFN TV L+ Sbjct: 557 EADNTKTRTLPVFNLTVALQ 576 >2HZ7-A nrPDB Length = 851 Score = 353 bits (907), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 229/574 (39%), Positives = 301/574 (52%), Gaps = 68/574 (11%) Query: 263 QVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMV 322 +V TRFPP+P+G H+GH A +F A+ G LR DDTNPE ++ +I D + Sbjct: 66 RVVTRFPPDPSGYAHLGHVFASLLDFNTARQYGGQFNLRMDDTNPELARQEYVDSIADDL 125 Query: 323 AWLGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEEL---KGHNTLP---SPW 375 WLG YASDYFD+ YA+A +LIR+G AYV EEL +G+ T P SP+ Sbjct: 126 KWLGLDWGEHFYYASDYFDRYYAYAEQLIRQGDAYVESVSPEELSRLRGNATTPGTPSPY 185 Query: 376 RDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM---DPVAYRVKYTPHHRTGDKW 432 RDR +EE+L L M+ G+F++GE LR K+ + M DPV YR+ PH RT D+W Sbjct: 186 RDRSVEENLDLLRRMKAGEFADGEHVLRAKIDLTAPNMKLRDPVLYRIVNKPHFRTSDEW 245 Query: 433 CIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYC-PVQWEYGRLNLHY 491 IYP YD+ H L D+IE +THS+C+ EF R+ Y WL L+ P Q+E+GR L Y Sbjct: 246 HIYPAYDFEHPLQDAIEGVTHSMCSLEFVDNRAIYDWLMEKLNFDPRPHQYEFGRRGLEY 305 Query: 492 AVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPH 551 + SKRK+ +LV G V WDDPR+ TL A RR G PEA+ F A++GV+ T++ Sbjct: 306 TITSKRKLRELVQAGRVSGWDDPRMPTLRAQRRLGVTPEAVRAFAAQIGVSRTNRTVDIA 365 Query: 552 LLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETK---------- 601 + E VRD LN APR MAVL+ ++V +TN K+L + P +P D + Sbjct: 366 VYENAVRDDLNHRAPRVMAVLDPVKVTLTNLDGEKTLSL--PYWPHDVVRDSPDGLVGMP 423 Query: 602 ---------GFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVK 652 VP ++IER DF P GFKRL G V LR G +I Sbjct: 424 GGGRVAPEEAVRDVPLTRELYIERDDFSPAPPKGFKRLTPGGTVRLRGAG-IIRADDFGT 482 Query: 653 GPSGCVESLEVTCRRADAGEKPKAFIHWVS--QPLMCEVRLYERLFQHKNPE-------- 702 +G V + T DA K IHWVS + L E RLY+RLF+ +PE Sbjct: 483 DEAGQVTHIRATLLGEDA--KAAGVIHWVSAERALPAEFRLYDRLFRVPHPEGENADVED 540 Query: 703 ---DPTE-------------VPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERL 746 P E V GF+ L SL V+ V+ SVA ++QFER Sbjct: 541 DSAGPAEHEAEPGAGQETAPVSQGFMRYLTPDSLRVL-RGYVEPSVAGDPADTRYQFERQ 599 Query: 747 GYFSVDP------DSHQGKLVFNRTVTLKEDPGK 774 GYF DP DS + LVF R +TLK+ GK Sbjct: 600 GYFWRDPVELERVDSREDALVFGRIITLKDTWGK 633 >3AII-A nrPDB Length = 553 Score = 159 bits (401), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 114/389 (29%), Positives = 175/389 (44%), Gaps = 11/389 (2%) Query: 242 GYVVTPHTMNLLKQHLEITG--GQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICF 299 G +T K E+ G G+V RF P P+G LHIGHA+A N YA+ +G Sbjct: 73 GLEITERKQKKRKGLRELAGVKGEVVLRFAPNPSGPLHIGHARAAILNHEYARKYDGRLI 132 Query: 300 LRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCH 359 LR +DT+P + + + + I + WLG + SD + Y + +LI RG AYVC Sbjct: 133 LRIEDTDPRRVDPEAYDMIPADLEWLGVEWDETVIQSDRMETYYEYTEKLIERGGAYVCT 192 Query: 360 QRGEELKGHNTLPSPWRDRPM--EESLLLFEAMRKGKFSEGEATLRMKLVMEDGK---MD 414 R EE + R + E+L + M + K EG A +R+K + D Sbjct: 193 CRPEEFRELKNRGEACHCRSLGFRENLQRWREMFEMK--EGSAVVRVKTDLNHPNPAIRD 250 Query: 415 PVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNAL 474 V+ R+ H RTG ++ +YP +++ + D + +TH L K+ A R +L L Sbjct: 251 WVSMRIVEAEHPRTGTRYRVYPMMNFSVAVDDHLLGVTHVLRGKDHLANREKQEYLYRHL 310 Query: 475 DVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINN 534 P YGRL + +S + + G WDDPRL TL A+ RRG PEAI Sbjct: 311 GWEPPEFIHYGRLKMDDVALSTSGAREGILRGEYSGWDDPRLGTLRAIARRGIRPEAIRK 370 Query: 535 FCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPN 594 +GV +A +TM + R +L + A R + +++ + P + ++ P Sbjct: 371 LMVEIGVKIADSTMSWKKIYGLNRSILEEEARRYFFAADPVKLEVVGLPG--PVRVERPL 428 Query: 595 FPADETKGFHQVPFAPIVFIERTDFKEEP 623 P G + V++ D E P Sbjct: 429 HPDHPEIGNRVLELRGEVYLPGDDLGEGP 457 >3TL4-X nrPDB Length = 187 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 57/193 (29%), Positives = 102/193 (52%), Gaps = 15/193 (7%) Query: 1 MAALDSLS-LFTSLGLSEQKARETLKNSALSAQL----REAATQAQQTLGSTIDKATGIL 55 M++++ L+ LF+ +G ++K +E +KN +S L +E + Q +K+T L Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDYQW------NKSTRAL 54 Query: 56 LYGLASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGV 113 ++ LAS ++ D + +V+ I + + T Q+ AA +YV+++ + + GV Sbjct: 55 VHNLASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANG-EASTKMGMNENSGV 113 Query: 114 GVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMG-EARAVLKWADGKMIKNEVDMQ 172 G+ +T +Q+ V I ++ ++L ERY G+ + LKWAD + K +D + Sbjct: 114 GIEITEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQE 173 Query: 173 VLHLLGPKLEADL 185 VL LLGPK E DL Sbjct: 174 VLKLLGPKDERDL 186 >2CFO-A nrPDB Length = 492 Score = 70.9 bits (172), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 43/108 (39%), Positives = 60/108 (55%), Gaps = 9/108 (8%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR R P P G LHIG A+ FN+ YA+ G LR +DT+ E+ ++ I + + Sbjct: 2 VRVRLAPSPTGNLHIGTARTAVFNWLYARHRGGKFILRIEDTDRERSRPEYTENILEGLQ 61 Query: 324 WLGYT----PYKVTYASDYFDQLYAWAVE-LIRRGLAYVCHQRGEELK 366 WLG T PY + SD D LY A++ L+ +GLAY C+ EEL+ Sbjct: 62 WLGLTWDEGPY---FQSDRLD-LYRQAIQTLLDKGLAYYCYCTPEELE 105 >6B1P-A nrPDB Length = 471 Score = 65.9 bits (159), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 73/287 (25%), Positives = 118/287 (41%), Gaps = 31/287 (10%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 + TRF P P G LHIG + FN+ +A+AN G FLR +DT+ + + AI + Sbjct: 12 IVTRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIIEAFK 71 Query: 324 WLGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEE 382 W+G ++ Y S F+ + +L+ AY C+ +EL ++ P + Sbjct: 72 WVGLEYDGEILYQSKRFEIYKEYIQKLLDEDKAYYCYMSKDELDALREEQKARKETPRYD 131 Query: 383 SLLLFEAMRKGKFSEG-EATLRMKLVMED--GKMDPVAYRVKYTPHHRTGDKWCI----- 434 + KG +G E +R+K+ + G D V VK + D + I Sbjct: 132 NRY---RDFKGTPPKGIEPVVRIKVPQNEVIGFNDGVKGEVKVNTNEL--DDFIIARSDG 186 Query: 435 YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNLHYAV 493 PTY++ + D++ IT + + + L AL+ P + LN Sbjct: 187 TPTYNFVVIVDDALMGITDVIRGDDHLSNTPKQIVLYKALNFKIPNFFHVPMILNEEGQK 246 Query: 494 VSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 540 +SKR GA D + G+ EA+ NF R+G Sbjct: 247 LSKRH-------GATNVMD---------YQEMGYLKEALVNFLVRLG 277 >2JA2-A nrPDB Length = 498 Score = 65.5 bits (158), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 74/307 (24%), Positives = 122/307 (39%), Gaps = 47/307 (15%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G H+G + FN+ YA+ G R +DT+ +++ + + A+ D + Sbjct: 7 VRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALR 66 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTL 371 WLG Y PY+ + ++ + + A L+ G AY EE++ + Sbjct: 67 WLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLA---RLLAAGEAYHAFSTPEEVEARHV- 122 Query: 372 PSPWRDRPMEESLL---LFEAMRKGKFSEGE---ATLRM---KLVMEDGKMDPVAYRVKY 422 + R+ + L +A R +EG LRM L D PV + Sbjct: 123 -AAGRNPKLGYDNFDRHLTDAQRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGS 181 Query: 423 TPH----HRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYC 478 P +GD P Y + D++ ITH L ++ L AL Sbjct: 182 VPDFALTRASGD-----PLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALI--- 233 Query: 479 PVQWEYGRLNLHYAVVSKRKILQLVATGAVR-DWDDPRLFTLTALRRRGFPPEAINNFCA 537 R+ + + + ++ G + DP+ L A R RGF PE + N+ A Sbjct: 234 -------RIGVAERIPKFAHLPTVLGEGTKKLSKRDPQ-SNLFAHRDRGFIPEGLLNYLA 285 Query: 538 RVGVTVA 544 +G ++A Sbjct: 286 LLGWSIA 292 >4G6Z-A nrPDB Length = 490 Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 7/106 (6%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VRTRF P P G +H+G+ ++ + + +A+ G LR +DT+ E+ + AI + +A Sbjct: 26 VRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILEGMA 85 Query: 324 WLGYT----PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEEL 365 WLG PY D + ++ A ++ +GL Y C+ EEL Sbjct: 86 WLGLDYDEGPYYQMQRMDRYREVLA---QMQEKGLVYPCYMSTEEL 128 >4GRI-A nrPDB Length = 512 Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 71/305 (23%), Positives = 123/305 (40%), Gaps = 53/305 (17%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 R R+ P P G+ HIG + FN+ +AK+ G LR +DT+ + + + + Sbjct: 25 TRVRYAPSPTGLQHIGGIRTALFNYFFAKSCGGKFLLRIEDTDQSRYSPEAENDLYSSLK 84 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCH------QRGEEL 365 WLG Y PY + S + Q +A LI G AY C+ +R +++ Sbjct: 85 WLGISFDEGPVVGGDYAPYVQSQRSAIYKQ---YAKYLIESGHAYYCYCSPERLERIKKI 141 Query: 366 KGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME-DGKMDPVAY-RVKYT 423 + N +P P DR L E + + + +R K+ +E D D + R+ + Sbjct: 142 QNINKMP-PGYDRHCRN--LSNEEVENALIKKIKPVVRFKIPLEGDTSFDDILLGRITWA 198 Query: 424 PHHRTGDKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALD---- 475 + D + PTY + + D + ITH L +E+ + + L A Sbjct: 199 NKDISPDPVILKSDGLPTYHLANVVDDYLMKITHVLRAQEWVSSGPLHVLLYKAFKWKPP 258 Query: 476 VYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNF 535 +YC + G +K+ + + A+R + + G+ PEAI N+ Sbjct: 259 IYCHLPMVMGN--------DGQKLSKRHGSTALRQFIE-----------DGYLPEAIINY 299 Query: 536 CARVG 540 +G Sbjct: 300 VTLLG 304 >2O5R-A nrPDB Length = 481 Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 68/298 (22%), Positives = 120/298 (40%), Gaps = 39/298 (13%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G LH+G A+ FNF +A+ G LR +DT+ E+ E ++ + + + Sbjct: 14 VRVRFAPSPTGFLHVGGARTALFNFLFARKEKGKFILRIEDTDLERSEREYEEKLMESLR 73 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEEL-----K 366 WLG + PY+ + + + + A L++ G AY + EE+ K Sbjct: 74 WLGLLWDEGPDVGGDHGPYRQSERVEIYRE---HAERLVKEGKAYYVYAYPEEIEEMREK 130 Query: 367 GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHH 426 + +P + M E E R+ + + K+ +D ++ V Sbjct: 131 LLSEGKAPHYSQEMFEKFDTPERRREYEEKGLRPAVFFKMPRKDYVLNDVVKGEVVFKTG 190 Query: 427 RTGDKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQW 482 GD + PTY++ + D + ITH + + + L A + PV Sbjct: 191 AIGDFVIMRSNGLPTYNFACVVDDMLMEITHVIRGDDHLSNTLRQLALYEAFEKAPPV-- 248 Query: 483 EYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 540 + ++ K+ + AT ++ A R G+ PEA+ N+ A +G Sbjct: 249 -FAHVSTILGPDGKKLSKRHGAT------------SVEAFRDMGYLPEALVNYLALLG 293 >6BRL-A nrPDB Length = 511 Score = 60.8 bits (146), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 78/347 (22%), Positives = 133/347 (38%), Gaps = 99/347 (28%) Query: 263 QVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMV 322 +VR RF P P G LH+G + +++ +AK N G LR +DT+ ++ I + + Sbjct: 11 KVRVRFAPSPTGPLHLGGVRTALYDYLFAKHNGGDFILRIEDTDTQRYVPGSEEYIMEAL 70 Query: 323 AWLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEE------ 364 W+G Y PY+ + D +D+ + ++++ AY+ EE Sbjct: 71 EWIGMVPDESPKHGGPYAPYRQSERRDIYDR---YTEQILKTDYAYLAFDTPEELDQIRA 127 Query: 365 ------------------LKGHNTLP-----------SPWRDR---PMEESLLLFEAMRK 392 L+ +LP +P+ R P++ + L + +R Sbjct: 128 EFEARGDVFAYNYETRNRLRNSISLPEEEVKKLLEEKTPYVIRFKMPLDRIINLNDIIR- 186 Query: 393 GKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHIT 452 GKFS TL K+++++ M PTY + + + D IT Sbjct: 187 GKFSVNTNTLDDKVLVKNDGM----------------------PTYHFANIIDDHEMKIT 224 Query: 453 HSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWD 512 H + +E+ + + L A+ P E+ L+L K K+ + RD D Sbjct: 225 HVIRGEEWLPSMALHVLLYEAMGWDAP---EFAHLSLILKPEGKGKL-------SKRDGD 274 Query: 513 D------PRLFTLTA-------LRRRGFPPEAINNFCARVGVTVAQT 546 P FT +A R G+ PEA N A +G + A Sbjct: 275 KFGFPVFPLNFTDSATGNTSAGYREEGYLPEAFINMVAMLGWSPADN 321 >5TGT-A nrPDB Length = 502 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 75/311 (24%), Positives = 123/311 (39%), Gaps = 60/311 (19%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VRTR P P G H+G A FN +A+ + G LR +DT+ + + I D + Sbjct: 12 VRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDTDQLRSTRESEQQIYDALR 71 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTL 371 WLG + PY+ + + + ++ EL+ +G A+ C E L Sbjct: 72 WLGIEWDEGPDVGGPHGPYRQSERGHIYKK---YSDELVEKGHAFTCFCTPERLDAVRAE 128 Query: 372 PSPWRDRPMEESLLLF----EAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKY-TPHH 426 ++ P + + E R+ E T RMK+ E + P R P Sbjct: 129 QMARKETPRYDGHCMHLPKDEVQRRLAAGESHVT-RMKVPTEGVCVVPDMLRGDVEIPWD 187 Query: 427 RTGDKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNA---LDVYCP 479 R + + PTY + + D + ITH L +E WL +A + +Y Sbjct: 188 RMDMQVLMKADGLPTYFLANVVDDHLMGITHVLRGEE---------WLPSAPKLIKLYEY 238 Query: 480 VQWEYGRL-------NLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAI 532 WE +L N + +SKRK +P ++T R G+ P+A+ Sbjct: 239 FGWEQPQLCYMPLLRNPDKSKLSKRK--------------NPT--SITFYERMGYLPQAL 282 Query: 533 NNFCARVGVTV 543 N+ R+G ++ Sbjct: 283 LNYLGRMGWSM 293 >2CV2-A nrPDB Length = 468 Score = 54.3 bits (129), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 71/304 (23%), Positives = 116/304 (38%), Gaps = 52/304 (17%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 V TR P P G H+G A FN+ +A+ N G +R +DT+ + I + Sbjct: 2 VVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRIEDTDRARYVPGAEERILAALK 61 Query: 324 WLGYT---------PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEEL--------- 365 WLG + P+ S+ +A EL++RG AY + EEL Sbjct: 62 WLGLSYDEGPDVGGPHGPYRQSERLPLYQKYAEELLKRGWAYRAFETPEELEQIRKEKGG 121 Query: 366 ---KGHNTLP--SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 420 + N P + R R E ++ + R G +E + LR +V ++ ++ V Sbjct: 122 YDGRARNIPPEEAEERARRGEPHVIRLKVPRPGT-TEVKDELRGVVVYDNQEIPDVVLL- 179 Query: 421 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 480 K YPTY + + D + +T + +E+ + L A P Sbjct: 180 ----------KSDGYPTYHLANVVDDHLMGVTDVIRAEEWLVSTPIHVLLYRAFGWEAPR 229 Query: 481 QWEYGRL-NLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARV 539 + L N +SKRK + DW + GF PEA+ N+ + Sbjct: 230 FYHMPLLRNPDKTKISKRK------SHTSLDW----------YKAEGFLPEALRNYLCLM 273 Query: 540 GVTV 543 G ++ Sbjct: 274 GFSM 277 >3AL0-C nrPDB Length = 592 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 35/63 (55%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G LH+G A+ FN+ +A+ G LR +DT+ E+ ++ I + + Sbjct: 130 VRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSSREYEQQILESLR 189 Query: 324 WLG 326 W G Sbjct: 190 WCG 192 >3AKZ-B nrPDB Length = 487 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 35/63 (55%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G LH+G A+ FN+ +A+ G LR +DT+ E+ ++ I + + Sbjct: 25 VRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSSREYEQQILESLR 84 Query: 324 WLG 326 W G Sbjct: 85 WCG 87 >5H4V-A nrPDB Length = 488 Score = 52.4 bits (124), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 3/103 (2%) Query: 265 RTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAW 324 RTRF P P G LHIG A+ + + A+ G LR +DT+ ++ AI + + W Sbjct: 25 RTRFAPSPTGYLHIGGARTALYCWLEARRRGGQFVLRIEDTDRQRSTQAAIDAILEAMQW 84 Query: 325 --LGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEEL 365 LGY + Y + + A +L+ +G AY ++ EEL Sbjct: 85 LGLGYDEGPI-YQTQRVARYQEVAEQLLAQGKAYYAYETREEL 126 >4A91-A nrPDB Length = 298 Score = 38.1 bits (87), Expect = 0.014, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 9/105 (8%) Query: 259 ITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAI 318 +T Q RF P P+G LH G A ++ A+A G +R +D +P +E I Sbjct: 1 MTDTQYIGRFAPSPSGELHFGSLIAALGSYLQARARQGRWLVRIEDIDPPREVPGAAETI 60 Query: 319 CDMVA-----WLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVC 358 + W G ++ + D + + AW L +GL+Y C Sbjct: 61 LRQLEHYGLHWDGDVLWQ-SQRHDAYREALAW---LHEQGLSYYC 101 >1AYE-A nrPDB Length = 401 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 7 LSLFTSLGLSEQKARETLKN-SALSAQLREAATQAQQTLGSTIDKATGI-LLYGLASRLR 64 L F L QKA ++L++ ++ + Q G +ID + + Y A LR Sbjct: 305 LDDFDELSEVAQKAAQSLRSLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELR 364 Query: 65 DTRRLSFLV--SYIASKKIHTEPQLSAALEYVRSHP 98 DT R FL+ I T L A +E+VR HP Sbjct: 365 DTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 400 >3AEO-A nrPDB Length = 389 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 352 RGLAYVCHQRGEELKGHNTLPSPWRDRPME 381 +G+A VCH+RG L T SP +P+E Sbjct: 164 KGIAVVCHERGARLVVDATFTSPCFLKPLE 193 >1YXA-A nrPDB Length = 398 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 21/99 (21%) Query: 17 EQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLASRLRDTRRLSFLVSYI 76 ++KA+ + A +A ++ QA++ + + K T ++ L S L D R L LV+YI Sbjct: 132 QEKAKTLYQAEAFTADFQQPR-QAKKLINDYVRKQTQGMIKELVSDL-DKRTLMVLVNYI 189 Query: 77 ASKKIHTEPQLSAALEYVRSH---PLDPIDTVDFERECG 112 Y ++ P DP+DT E CG Sbjct: 190 ----------------YFKAKWKVPFDPLDTFKSEFYCG 212 >1DTD-A nrPDB Length = 303 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 4/96 (4%) Query: 7 LSLFTSLGLSEQKARETLKN-SALSAQLREAATQAQQTLGSTIDKATGI-LLYGLASRLR 64 L F L QKA ++L ++ + Q G +ID + + Y A LR Sbjct: 207 LDDFDELSEVAQKAAQSLSRLHGTKYKVGPICSVIYQASGGSIDWSYDYGIKYSFAFELR 266 Query: 65 DTRRLSFLV--SYIASKKIHTEPQLSAALEYVRSHP 98 DT R FL+ I T L A +E+VR HP Sbjct: 267 DTGRYGFLLPARQILPTAEETWLGLKAIMEHVRDHP 302 >3NYZ-A nrPDB Length = 261 Score = 30.0 bits (66), Expect = 4.3, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 26/46 (56%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPEQIEEA 125 KI TE +L + LEY RS+ ++P ++ E + + + + IE A Sbjct: 135 KILTERELESLLEYARSYGMEPAIVINDENDLDIALRIGARFIEIA 180 >3UD6-A nrPDB Length = 258 Score = 30.0 bits (66), Expect = 4.5, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 23/36 (63%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGV 115 KI TE +L + LEY RS+ ++PI ++ E + + + Sbjct: 135 KILTERELESLLEYARSYGMEPIIKINDENDLDIAL 170 >3TC6-A nrPDB Length = 258 Score = 28.9 bits (63), Expect = 7.9, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGV 115 KI TE +L + LEY RS+ ++P+ ++ E + + + Sbjct: 135 KILTERELESLLEYARSYGMEPLIVINDENDLDIAL 170 >2C3Z-A nrPDB Length = 222 Score = 28.9 bits (63), Expect = 9.0, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGV 115 KI TE +L + LEY RS+ ++P+ ++ E + + + Sbjct: 109 KILTERELESLLEYARSYGMEPLIEINDENDLDIAL 144 >3HOJ-A nrPDB Length = 248 Score = 28.9 bits (63), Expect = 9.1, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGV 115 KI TE +L + LEY RS+ ++P+ ++ E + + + Sbjct: 135 KILTERELESLLEYARSYGMEPLIKINDENDLDIAL 170 >4PEK-A nrPDB Length = 258 Score = 28.9 bits (63), Expect = 9.6, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGV 115 KI TE +L + LEY RS+ ++P+ ++ E + + + Sbjct: 135 KILTERELESLLEYARSYGMEPLIIINDENDLDIAL 170 >4IJB-A nrPDB Length = 256 Score = 28.9 bits (63), Expect = 9.7, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 23/36 (63%) Query: 80 KIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGV 115 KI TE +L + LEY RS+ ++P+ ++ E + + + Sbjct: 135 KILTERELESLLEYARSYGMEPLIEINDENDLDIAL 170 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4R3Z-C nrPDB 1194 0.0 4H3S-A nrPDB 971 0.0 5BNZ-A nrPDB 703 0.0 2RD2-A nrPDB 677 0.0 4P2B-A nrPDB 654 0.0 2HZ7-A nrPDB 651 0.0 5ZDO-A nrPDB 636 0.0 3AII-A nrPDB 466 e-131 2O5R-A nrPDB 290 1e-78 3TL4-X nrPDB 287 1e-77 5TGT-A nrPDB 286 3e-77 6B1P-A nrPDB 283 2e-76 4GRI-A nrPDB 282 6e-76 6BRL-A nrPDB 267 1e-71 2CV2-A nrPDB 266 3e-71 2JA2-A nrPDB 264 1e-70 2CFO-A nrPDB 263 1e-70 4G6Z-A nrPDB 250 1e-66 5H4V-A nrPDB 248 9e-66 3AKZ-B nrPDB 230 2e-60 3AL0-C nrPDB 228 6e-60 Sequences not found previously or not previously below threshold: 4A91-A nrPDB 142 4e-34 3L9X-A nrPDB 40 0.004 2G36-A nrPDB 37 0.032 3FNR-A nrPDB 36 0.070 5AH5-A nrPDB 34 0.30 2J5B-A nrPDB 34 0.32 4ARC-A nrPDB 33 0.64 3JXE-A nrPDB 32 0.84 1IQ0-A nrPDB 32 0.84 3IZO-F nrPDB 32 0.97 2ZUE-A nrPDB 32 1.1 5FAD-A nrPDB 32 1.4 4R3U-A nrPDB 31 1.7 2P8B-A nrPDB 30 4.7 1IRX-A nrPDB 30 4.7 2I34-A nrPDB 30 5.0 >4R3Z-C nrPDB Length = 799 Score = 1194 bits (3088), Expect = 0.0, Method: Composition-based stats. Identities = 775/775 (100%), Positives = 775/775 (100%) Query: 1 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 60 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA Sbjct: 25 MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLA 84 Query: 61 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 120 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE Sbjct: 85 SRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPE 144 Query: 121 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 180 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK Sbjct: 145 QIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPK 204 Query: 181 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 240 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT Sbjct: 205 LEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKT 264 Query: 241 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 300 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL Sbjct: 265 PGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 324 Query: 301 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 360 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ Sbjct: 325 RFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 384 Query: 361 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 420 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV Sbjct: 385 RGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 444 Query: 421 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 480 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV Sbjct: 445 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 504 Query: 481 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 540 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG Sbjct: 505 QWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVG 564 Query: 541 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 600 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET Sbjct: 565 VTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADET 624 Query: 601 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 660 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES Sbjct: 625 KGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 684 Query: 661 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 720 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL Sbjct: 685 LEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASL 744 Query: 721 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 775 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV Sbjct: 745 HVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV 799 >4H3S-A nrPDB Length = 817 Score = 971 bits (2511), Expect = 0.0, Method: Composition-based stats. Identities = 319/829 (38%), Positives = 452/829 (54%), Gaps = 75/829 (9%) Query: 1 MAALDSLS-LFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGL 59 M++++ L+ LF+ +G ++K +E +KN +S L + + +K+T L++ L Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDY--QWNKSTRALVHNL 58 Query: 60 ASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIV 117 AS ++ D + +V+ I + + T Q+ AA +YV+++ + + GVG+ + Sbjct: 59 ASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANG-EASTKMGMNENSGVGIEI 117 Query: 118 TPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMG-EARAVLKWADGKMIKNEVDMQVLHL 176 T +Q+ V I ++ ++L ERY G+ + LKWAD + K +D +VL L Sbjct: 118 TEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKL 177 Query: 177 LGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGE 236 LGPK E DL K E+ +AK +N ++ ++ + G HK GE Sbjct: 178 LGPKDERDL---IKKKTKNNEKKKTNSAKKSSDNSASSGPKRTMFNE--GFLGDLHKVGE 232 Query: 237 NYKTPGYVVTPHTM-NLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANN 295 N P L+K+HLE+TGG+VRTRFPPEPNG LHIGH+KAI NFGYAK +N Sbjct: 233 N---------PQAYPELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIMVNFGYAKYHN 283 Query: 296 GICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLA 355 G C+LRFDDTNPEKE ++F +I MV+WLG+ P+K+TY+SDYFD+LY A LI+ G A Sbjct: 284 GTCYLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITYSSDYFDELYRLAEVLIKNGKA 343 Query: 356 YVCHQRGEELK-----------GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRM 404 YVCH EE+K G RD+ +E++L F MR GK+ GEA LRM Sbjct: 344 YVCHCTAEEIKRGRGIKEDGTPGGERYACKHRDQSIEQNLQEFRDMRDGKYKPGEAILRM 403 Query: 405 KLVMEDGK---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQ 461 K + D +AYRV PH RTG KW IYPTYD+THCL DS+E+ITHSLCT EF Sbjct: 404 KQDLNSPSPQMWDLIAYRVLNAPHPRTGTKWRIYPTYDFTHCLVDSMENITHSLCTTEFY 463 Query: 462 ARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTA 521 R SY WLC+ + V+ P Q EYGRLN+ V+SKRKI QLV VR WDDPRLFTL A Sbjct: 464 LSRESYEWLCDQVHVFRPAQREYGRLNITGTVLSKRKIAQLVDEKFVRGWDDPRLFTLEA 523 Query: 522 LRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITN 581 +RRRG PP AI +F +GVT + T ++ E+ VR L DT PR M VL+ + V++ N Sbjct: 524 IRRRGVPPGAILSFINTLGVTTSTTNIQVVRFESAVRKYLEDTTPRLMFVLDPVEVVVDN 583 Query: 582 FPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEE-PEPGFKRLAWGQPVGLRH 640 +P P G VPF +IER+DF E + F RL QPVGL Sbjct: 584 LSDDYEELATIPYRPGTPEFGERTVPFTNKFYIERSDFSENVDDKEFFRLTPNQPVGLIK 643 Query: 641 TGYVIELQHVVKGPSGCVESLEVT----CRRADAGEKPKAFIHWV------SQPL-MCEV 689 + + + + K +G + + V +KPK +I WV + PL + E Sbjct: 644 VSHTVSFKSLEKDEAGKIIRIHVNYDNKVEEGSKPKKPKTYIQWVPISSKYNSPLRVTET 703 Query: 690 RLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVA---------------- 733 R+Y +LF+ +NP + P GFL D+N S V ++++ + Sbjct: 704 RVYNQLFKSENP---SSHPEGFLKDINPESEVVYKESVMEHNFGDVVKNSPWVVDSVKNS 760 Query: 734 --------LAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGK 774 +K +FQ R+GYF++D +S K++ NR V+LK+ K Sbjct: 761 EFYVEEDKDSKEVCRFQAMRVGYFTLDKESTTSKVILNRIVSLKDATSK 809 >5BNZ-A nrPDB Length = 564 Score = 703 bits (1815), Expect = 0.0, Method: Composition-based stats. Identities = 259/553 (46%), Positives = 339/553 (61%), Gaps = 27/553 (4%) Query: 246 TPHTMNLLKQHLEI---TGG--QVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFL 300 T N L+Q ++ G ++ TRFPPEPNG LHIGHAK+I NFG A+ G C L Sbjct: 14 TTAAPNFLRQIVQADLDAGKHAKIVTRFPPEPNGYLHIGHAKSICLNFGLAQEFAGDCHL 73 Query: 301 RFDDTNPEKEEAKFFTAICDMVAWLGYTP-YKVTYASDYFDQLYAWAVELIRRGLAYVCH 359 RFDDTNP KE+ ++ AI + WLG+ +V YAS+YFDQL+AWAVELI+ G A+VC Sbjct: 74 RFDDTNPAKEDQEYIDAIEADIKWLGFQWSGEVCYASNYFDQLHAWAVELIKAGKAFVCD 133 Query: 360 QRGEELK---GHNTLP---SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM 413 EE++ G T P SP+RDR +EE+L LF M+ G+F +G +LR K+ M M Sbjct: 134 LGPEEMREYRGTLTEPGRNSPYRDRSVEENLDLFARMKAGEFPDGARSLRAKIDMGSPNM 193 Query: 414 ---DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWL 470 DP+ YR+++ HH+TGDKWCIYP+YD+TH D+IE ITHS+CT EF+ R Y W Sbjct: 194 NLRDPILYRIRHAHHHQTGDKWCIYPSYDFTHGQSDAIEGITHSICTLEFEDHRPLYEWF 253 Query: 471 CNALDVYC-PVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPP 529 L V P Q+E+ RLNL+Y V SKRK+ QLV G V WDDPR+ TL+ RRRG+ P Sbjct: 254 LANLPVPAQPRQYEFSRLNLNYTVTSKRKLKQLVDEGHVSGWDDPRMSTLSGYRRRGYTP 313 Query: 530 EAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLD 589 E+I NFC +GV A ++ +LE +RD L+ TAPRAM VL+ L+V+ITN+P + + Sbjct: 314 ESIRNFCEMIGVNRASGVVDIGMLEFSIRDHLDATAPRAMCVLKPLKVVITNYPEGQVEN 373 Query: 590 IQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQH 649 +++P P E G +PF +FI+ DF+E P G+KRL G V LR YVI Sbjct: 374 LELPRHPK-EDMGVRVLPFGRELFIDAGDFEEVPPAGYKRLIPGGEVRLRG-SYVIRADE 431 Query: 650 VVKGPSGCVESLEV-----TCRRADAGEKPKAFIHWV--SQPLMCEVRLYERLFQHKNPE 702 +K G + L T + G K K IHWV + CEVRLY+RLF+ NPE Sbjct: 432 AIKDADGNIVELRCSYDPDTLGKNPEGRKVKGVIHWVPAEGSVECEVRLYDRLFRSANPE 491 Query: 703 DPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVD-PDSHQGKLV 761 E G FL ++N SL V+ + S+ A P D+FQFER GYF D DS GK V Sbjct: 492 K-AEEGGSFLDNINADSLQVLAGCRAEPSLGQANPEDRFQFEREGYFVADLKDSRPGKPV 550 Query: 762 FNRTVTLKEDPGK 774 FNRTVTL++ G+ Sbjct: 551 FNRTVTLRDSWGQ 563 >2RD2-A nrPDB Length = 556 Score = 677 bits (1747), Expect = 0.0, Method: Composition-based stats. Identities = 247/553 (44%), Positives = 333/553 (60%), Gaps = 32/553 (5%) Query: 244 VVTPHTMNLLKQHLE--ITGGQ---VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGIC 298 N ++Q ++ + G+ V TRFPPEPNG LHIGHAK+I NFG A+ G C Sbjct: 3 EAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYKGQC 62 Query: 299 FLRFDDTNPEKEEAKFFTAICDMVAWLGYTP-YKVTYASDYFDQLYAWAVELIRRGLAYV 357 LRFDDTNP KE+ ++ +I + V WLG+ V Y+SDYFDQL+A+A+ELI +GLAYV Sbjct: 63 NLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLHAYAIELINKGLAYV 122 Query: 358 CHQRGE---ELKGHNTLP---SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDG 411 E E +G T P SP+RDR +EE+L LFE MR G F EG+A LR K+ M Sbjct: 123 DELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMASP 182 Query: 412 K---MDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYF 468 DPV YR+K+ HH+TG+KWCIYP YD+THC+ D++E ITHSL T EFQ R Y Sbjct: 183 FIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLRTLEFQDNRRLYD 242 Query: 469 WLCNALDVYC-PVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGF 527 W+ + + + P Q+E+ RLNL Y V+SKRK+ LV V WDDPR+ T++ LRRRG+ Sbjct: 243 WVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGY 302 Query: 528 PPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKS 587 +I FC R+GVT T+E LE+C+R+ LN+ APRAMAV++ ++++I N+ Sbjct: 303 TAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYQGEGE 362 Query: 588 LDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIEL 647 + + +PN P G QVPF+ ++I+R DF+EE +KRL G+ V LR+ YVI+ Sbjct: 363 M-VTMPNHPNKPEMGSRQVPFSGEIWIDRADFREEANKQYKRLVLGKEVRLRN-AYVIKA 420 Query: 648 QHVVKGPSGCVESLEVT------CRRADAGEKPKAFIHWVS--QPLMCEVRLYERLFQHK 699 + V K G + ++ T + G K K IHWVS L E+RLY+RLF Sbjct: 421 ERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPVEIRLYDRLFSVP 480 Query: 700 NPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDP-DSHQG 758 NP + FLS +N SL V+ + S+ A FQFER GYF +D S Sbjct: 481 NPGAADD----FLSVINPESL-VIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRHSTAE 535 Query: 759 KLVFNRTVTLKED 771 K VFNRTV L++ Sbjct: 536 KPVFNRTVGLRDT 548 >4P2B-A nrPDB Length = 576 Score = 654 bits (1686), Expect = 0.0, Method: Composition-based stats. Identities = 245/560 (43%), Positives = 321/560 (57%), Gaps = 41/560 (7%) Query: 248 HTMNLLKQHLE---ITGGQ--VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRF 302 H +N LKQ +E TG V TRFPPEPNG LH+GHAK++ NFG AKA G C LRF Sbjct: 20 HMVNFLKQIVEEDLRTGKHKTVITRFPPEPNGFLHLGHAKSVCLNFGLAKAFGGRCHLRF 79 Query: 303 DDTNPEKEEAKFFTAICDMVAWLGYTPY-KVTYASDYFDQLYAWAVELIRRGLAYVCHQR 361 DDTNP KEE ++ +I V WLG + YASDYF QLY WA LI++GLA+V Sbjct: 80 DDTNPMKEETRYIESIQRDVRWLGGDWGNHLYYASDYFQQLYDWAELLIKKGLAFVDDDS 139 Query: 362 GEELK---GHNTLP---SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM-- 413 EE++ G + P SP+R+R +EE+L LF MR G+F EG LR K+ M M Sbjct: 140 LEEIRRKRGSISQPGENSPFRERSIEENLDLFRRMRAGEFEEGSRVLRAKIDMTHSNMNM 199 Query: 414 -DPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCN 472 DPV YR+ H RTG++W IYP YDY H DSIE+ITHS+CT EF R Y W Sbjct: 200 RDPVLYRILKKEHPRTGNQWVIYPMYDYAHGQSDSIENITHSICTLEFDLHRILYDWFQE 259 Query: 473 ALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAI 532 L++ Q E+ RLN+ Y V+SKRK+L LV V WDDPRL TL+ LRRRG PP A+ Sbjct: 260 KLEITRTRQIEFARLNVTYTVMSKRKLLALVTEKWVDGWDDPRLPTLSGLRRRGVPPSAL 319 Query: 533 NNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQV 592 +FC +VGV ++T++ +LE C+RD L+ A R A+ + + V ITN+ K I Sbjct: 320 RDFCDKVGVARRESTIKVEVLEKCIRDALHVVAHRRFAIQDPIAVTITNY-GDKVETITA 378 Query: 593 PNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVK 652 N P DE+ G ++ F+ ++I+R DF E P G++RLA G V L+H Y I+ VVK Sbjct: 379 ANHPEDESFGTRELHFSKKLYIDRDDFMENPPAGYRRLAPGAEVRLKH-AYWIKCVDVVK 437 Query: 653 GPSGCVESLEVT-------CRRADAGEKPKAFIHWVSQ--PLMCEVRLYERLFQHKNP-- 701 SG V L T C A G K K IHW+S+ + E+R++ RLF NP Sbjct: 438 DASGLVTELLCTYDPQTKNCSVAPDGRKVKGAIHWLSEKDAVPAEIRIFGRLFTKPNPEE 497 Query: 702 EDPTEVPGGFLSDLNLASLHVVDAALVDCSVALA---KPFDKFQFERLGYFSVD------ 752 ED + + ++N SL V V+ S A + P QFERLG+F+ D Sbjct: 498 EDESNPNASWRENINKESLKVYK-GFVERSAADSAAFPPQSSLQFERLGFFTPDGSTLPE 556 Query: 753 -PDSHQGK--LVFNRTVTLK 769 D+ + + VFN TV L+ Sbjct: 557 EADNTKTRTLPVFNLTVALQ 576 >2HZ7-A nrPDB Length = 851 Score = 651 bits (1680), Expect = 0.0, Method: Composition-based stats. Identities = 231/591 (39%), Positives = 306/591 (51%), Gaps = 73/591 (12%) Query: 251 NLLKQHLEI---TGG--QVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDT 305 N + + +E G +V TRFPP+P+G H+GH A +F A+ G LR DDT Sbjct: 49 NFITEIIERDLEAGKYPRVVTRFPPDPSGYAHLGHVFASLLDFNTARQYGGQFNLRMDDT 108 Query: 306 NPEKEEAKFFTAICDMVAWLGYTPY-KVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEE 364 NPE ++ +I D + WLG YASDYFD+ YA+A +LIR+G AYV EE Sbjct: 109 NPELARQEYVDSIADDLKWLGLDWGEHFYYASDYFDRYYAYAEQLIRQGDAYVESVSPEE 168 Query: 365 L---KGHNTLP---SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKM---DP 415 L +G+ T P SP+RDR +EE+L L M+ G+F++GE LR K+ + M DP Sbjct: 169 LSRLRGNATTPGTPSPYRDRSVEENLDLLRRMKAGEFADGEHVLRAKIDLTAPNMKLRDP 228 Query: 416 VAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALD 475 V YR+ PH RT D+W IYP YD+ H L D+IE +THS+C+ EF R+ Y WL L+ Sbjct: 229 VLYRIVNKPHFRTSDEWHIYPAYDFEHPLQDAIEGVTHSMCSLEFVDNRAIYDWLMEKLN 288 Query: 476 VYC-PVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINN 534 P Q+E+GR L Y + SKRK+ +LV G V WDDPR+ TL A RR G PEA+ Sbjct: 289 FDPRPHQYEFGRRGLEYTITSKRKLRELVQAGRVSGWDDPRMPTLRAQRRLGVTPEAVRA 348 Query: 535 FCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPN 594 F A++GV+ T++ + E VRD LN APR MAVL+ ++V +TN K+L + P Sbjct: 349 FAAQIGVSRTNRTVDIAVYENAVRDDLNHRAPRVMAVLDPVKVTLTNLDGEKTLSL--PY 406 Query: 595 FPAD-------------------ETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQP 635 +P D + VP ++IER DF P GFKRL G Sbjct: 407 WPHDVVRDSPDGLVGMPGGGRVAPEEAVRDVPLTRELYIERDDFSPAPPKGFKRLTPGGT 466 Query: 636 VGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVS--QPLMCEVRLYE 693 V LR G +I +G V + T DA K IHWVS + L E RLY+ Sbjct: 467 VRLRGAG-IIRADDFGTDEAGQVTHIRATLLGEDA--KAAGVIHWVSAERALPAEFRLYD 523 Query: 694 RLFQHKNPE-----------DPTEV-------------PGGFLSDLNLASLHVVDAALVD 729 RLF+ +PE P E GF+ L SL V+ V+ Sbjct: 524 RLFRVPHPEGENADVEDDSAGPAEHEAEPGAGQETAPVSQGFMRYLTPDSLRVL-RGYVE 582 Query: 730 CSVALAKPFDKFQFERLGYFSVDP------DSHQGKLVFNRTVTLKEDPGK 774 SVA ++QFER GYF DP DS + LVF R +TLK+ GK Sbjct: 583 PSVAGDPADTRYQFERQGYFWRDPVELERVDSREDALVFGRIITLKDTWGK 633 >5ZDO-A nrPDB Length = 548 Score = 636 bits (1641), Expect = 0.0, Method: Composition-based stats. Identities = 245/539 (45%), Positives = 319/539 (59%), Gaps = 31/539 (5%) Query: 254 KQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAK 313 + E ++ TRFPPEPNG LHIGHA++I NFG A+ G C LRFDDTNPE E+ + Sbjct: 15 RDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEE 74 Query: 314 FFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTL-- 371 + AI + V WLG+ P +V YASDYF+ +Y A+ LI+ G AYV EE+ Sbjct: 75 YARAIEEDVRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSELRAQGK 134 Query: 372 PSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGK---MDPVAYRVKYTPHHRT 428 PSP+R+R +EE+L LFE MR+G+F G LR K+ DPV YR+ + PH+ Sbjct: 135 PSPYRERSVEENLELFERMRRGEFPTGSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYHV 194 Query: 429 GDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYC-------PVQ 481 GD+W IYP YD+ H L D IE +THSLCT EF+ R+ Y W+ L C P Q Sbjct: 195 GDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENLKGKCGLPTSPRPHQ 254 Query: 482 WEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGV 541 +E+ RL+L + V+SKRK+++LV G V WDDPRL TL LRRRG PEAI F + G+ Sbjct: 255 YEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTGI 314 Query: 542 TVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETK 601 + + +E L E VRD LN APR + V++ L+V++TN+ + I+ P +P D K Sbjct: 315 SRNEAQIEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEW--IEAPYWPRDIPK 372 Query: 602 -GFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVES 660 G +PF+P ++IERTDF P G+KRLA GQ V LRH YVIEL+ VV G V Sbjct: 373 EGTRPLPFSPELYIERTDFSLNPPKGWKRLAPGQRVRLRH-AYVIELEDVV-EEGGEVRL 430 Query: 661 LEVTC------RRADAGEKPKAFIHWVS--QPLMCEVRLYERLFQHKNPEDPTEVPGGFL 712 L+ + G +PK IHWVS L E RLY RLF+ K+PE+ G FL Sbjct: 431 LKARIVPGTLGANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPEE----GGDFL 486 Query: 713 SDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDP-DSHQGKLVFNRTVTLKE 770 +LN +L VV ++ SVA ++Q ERLGYF DP DS LV NR V LKE Sbjct: 487 QNLNPEAL-VVKRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIVPLKE 544 >3AII-A nrPDB Length = 553 Score = 466 bits (1200), Expect = e-131, Method: Composition-based stats. Identities = 133/522 (25%), Positives = 207/522 (39%), Gaps = 63/522 (12%) Query: 242 GYVVTPHTMNLLKQHLEITG--GQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICF 299 G +T K E+ G G+V RF P P+G LHIGHA+A N YA+ +G Sbjct: 73 GLEITERKQKKRKGLRELAGVKGEVVLRFAPNPSGPLHIGHARAAILNHEYARKYDGRLI 132 Query: 300 LRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCH 359 LR +DT+P + + + + I + WLG + SD + Y + +LI RG AYVC Sbjct: 133 LRIEDTDPRRVDPEAYDMIPADLEWLGVEWDETVIQSDRMETYYEYTEKLIERGGAYVCT 192 Query: 360 QRGEELKGHNTLPSPWRDRPM--EESLLLFEAMRKGKFSEGEATLRMKLVMEDGK---MD 414 R EE + R + E+L + M + K EG A +R+K + D Sbjct: 193 CRPEEFRELKNRGEACHCRSLGFRENLQRWREMFEMK--EGSAVVRVKTDLNHPNPAIRD 250 Query: 415 PVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNAL 474 V+ R+ H RTG ++ +YP +++ + D + +TH L K+ A R +L L Sbjct: 251 WVSMRIVEAEHPRTGTRYRVYPMMNFSVAVDDHLLGVTHVLRGKDHLANREKQEYLYRHL 310 Query: 475 DVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINN 534 P YGRL + +S + + G WDDPRL TL A+ RRG PEAI Sbjct: 311 GWEPPEFIHYGRLKMDDVALSTSGAREGILRGEYSGWDDPRLGTLRAIARRGIRPEAIRK 370 Query: 535 FCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPN 594 +GV +A +TM + R +L + A R + +++ + P + ++ P Sbjct: 371 LMVEIGVKIADSTMSWKKIYGLNRSILEEEARRYFFAADPVKLEVVGLPG--PVRVERPL 428 Query: 595 FPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGP 654 P G + V++ D E P + L VI Sbjct: 429 HPDHPEIGNRVLELRGEVYLPGDDLGEGP------------LRLIDAVNVIY-------S 469 Query: 655 SGCVESLEVTCRRADAGEKP-KAFIHWV--SQPLMCEVRLYERLFQHKNPEDPTEVPGGF 711 G L + + + IHWV L EV Sbjct: 470 GG---ELRYHSEGIEEARELGASMIHWVPAESALEAEV---------------------- 504 Query: 712 LSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDP 753 + + V +++ + + D Q ER G+ +D Sbjct: 505 ---IMPDASRV--RGVIEADASELEVDDVVQLERFGFARLDS 541 >2O5R-A nrPDB Length = 481 Score = 290 bits (742), Expect = 1e-78, Method: Composition-based stats. Identities = 84/400 (21%), Positives = 143/400 (35%), Gaps = 48/400 (12%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G LH+G A+ FNF +A+ G LR +DT+ E+ E ++ + + + Sbjct: 14 VRVRFAPSPTGFLHVGGARTALFNFLFARKEKGKFILRIEDTDLERSEREYEEKLMESLR 73 Query: 324 WLGY---------TPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHN----- 369 WLG + S+ + A L++ G AY + EE++ Sbjct: 74 WLGLLWDEGPDVGGDHGPYRQSERVEIYREHAERLVKEGKAYYVYAYPEEIEEMREKLLS 133 Query: 370 TLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTG 429 +P + M E E R+ + + K+ +D ++ V G Sbjct: 134 EGKAPHYSQEMFEKFDTPERRREYEEKGLRPAVFFKMPRKDYVLNDVVKGEVVFKTGAIG 193 Query: 430 DKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYG 485 D + PTY++ + D + ITH + + + L A + PV Sbjct: 194 DFVIMRSNGLPTYNFACVVDDMLMEITHVIRGDDHLSNTLRQLALYEAFEKAPPVFAHVS 253 Query: 486 R-LNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVA 544 L +SKR ++ A R G+ PEA+ N+ A +G + Sbjct: 254 TILGPDGKKLSKRHGAT----------------SVEAFRDMGYLPEALVNYLALLGWSHP 297 Query: 545 QTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVI------ITNFPAAKSLDIQVPNFPA- 597 + E LE + D A+ + ++ + N P K ++ P F Sbjct: 298 EGK-ELLTLEELISSFSLDRLSPNPAIFDPQKLKWMNGYYLRNMPIEKLAELAKPFFEKA 356 Query: 598 -----DETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAW 632 DE + ++F EE F+ A Sbjct: 357 GIKIIDEEYFKKVLEITKERVEVLSEFPEESRFFFEDPAP 396 >3TL4-X nrPDB Length = 187 Score = 287 bits (734), Expect = 1e-77, Method: Composition-based stats. Identities = 55/189 (29%), Positives = 100/189 (52%), Gaps = 7/189 (3%) Query: 1 MAALDSLS-LFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGL 59 M++++ L+ LF+ +G ++K +E +KN +S L + + +K+T L++ L Sbjct: 1 MSSVEELTQLFSQVGFEDKKVKEIVKNKKVSDSLYKLIKETPSDY--QWNKSTRALVHNL 58 Query: 60 ASRLR--DTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIV 117 AS ++ D + +V+ I + + T Q+ AA +YV+++ + + GVG+ + Sbjct: 59 ASFVKGTDLPKSELIVNGIINGDLKTSLQVDAAFKYVKANG-EASTKMGMNENSGVGIEI 117 Query: 118 TPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMG-EARAVLKWADGKMIKNEVDMQVLHL 176 T +Q+ V I ++ ++L ERY G+ + LKWAD + K +D +VL L Sbjct: 118 TEDQVRNYVMQYIQENKERILTERYKLVPGIFADVKNLKELKWADPRSFKPIIDQEVLKL 177 Query: 177 LGPKLEADL 185 LGPK E DL Sbjct: 178 LGPKDERDL 186 >5TGT-A nrPDB Length = 502 Score = 286 bits (731), Expect = 3e-77, Method: Composition-based stats. Identities = 70/304 (23%), Positives = 114/304 (37%), Gaps = 42/304 (13%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VRTR P P G H+G A FN +A+ + G LR +DT+ + + I D + Sbjct: 12 VRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDTDQLRSTRESEQQIYDALR 71 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTL 371 WLG + PY+ + + + ++ EL+ +G A+ C E L Sbjct: 72 WLGIEWDEGPDVGGPHGPYRQSERGHIYKK---YSDELVEKGHAFTCFCTPERLDAVRAE 128 Query: 372 PSPWRDRPMEESLLLF----EAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV-KYTPHH 426 ++ P + + E R+ E T RMK+ E + P R P Sbjct: 129 QMARKETPRYDGHCMHLPKDEVQRRLAAGESHVT-RMKVPTEGVCVVPDMLRGDVEIPWD 187 Query: 427 RTGDKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQW 482 R + + PTY + + D + ITH L +E+ L P Sbjct: 188 RMDMQVLMKADGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWEQPQLC 247 Query: 483 EYGRL-NLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGV 541 L N + +SKRK ++T R G+ P+A+ N+ R+G Sbjct: 248 YMPLLRNPDKSKLSKRKNPT----------------SITFYERMGYLPQALLNYLGRMGW 291 Query: 542 TVAQ 545 ++ Sbjct: 292 SMPD 295 >6B1P-A nrPDB Length = 471 Score = 283 bits (725), Expect = 2e-76, Method: Composition-based stats. Identities = 71/293 (24%), Positives = 118/293 (40%), Gaps = 27/293 (9%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 + TRF P P G LHIG + FN+ +A+AN G FLR +DT+ + + AI + Sbjct: 12 IVTRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIIEAFK 71 Query: 324 WLGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEE 382 W+G ++ Y S F+ + +L+ AY C+ +EL ++ P + Sbjct: 72 WVGLEYDGEILYQSKRFEIYKEYIQKLLDEDKAYYCYMSKDELDALREEQKARKETPRYD 131 Query: 383 SLLLFEAMRKGKFSEG-EATLRMKLVMED--GKMDPVAYRVKYTPHHRTG---DKWCIYP 436 + KG +G E +R+K+ + G D V VK + + P Sbjct: 132 NRY---RDFKGTPPKGIEPVVRIKVPQNEVIGFNDGVKGEVKVNTNELDDFIIARSDGTP 188 Query: 437 TYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNLHYAVVS 495 TY++ + D++ IT + + + L AL+ P + LN +S Sbjct: 189 TYNFVVIVDDALMGITDVIRGDDHLSNTPKQIVLYKALNFKIPNFFHVPMILNEEGQKLS 248 Query: 496 KRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTM 548 KR GA D + G+ EA+ NF R+G + + Sbjct: 249 KRH-------GATNVMD---------YQEMGYLKEALVNFLVRLGWSYQDKEI 285 >4GRI-A nrPDB Length = 512 Score = 282 bits (720), Expect = 6e-76, Method: Composition-based stats. Identities = 71/307 (23%), Positives = 114/307 (37%), Gaps = 47/307 (15%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 R R+ P P G+ HIG + FN+ +AK+ G LR +DT+ + + + + Sbjct: 25 TRVRYAPSPTGLQHIGGIRTALFNYFFAKSCGGKFLLRIEDTDQSRYSPEAENDLYSSLK 84 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELK----- 366 WLG Y PY + S + Q +A LI G AY C+ E L+ Sbjct: 85 WLGISFDEGPVVGGDYAPYVQSQRSAIYKQ---YAKYLIESGHAYYCYCSPERLERIKKI 141 Query: 367 -GHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME-DGKMDPVAY-RVKYT 423 N +P P DR L E + + + +R K+ +E D D + R+ + Sbjct: 142 QNINKMP-PGYDRHCRN--LSNEEVENALIKKIKPVVRFKIPLEGDTSFDDILLGRITWA 198 Query: 424 PHHRTGDKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCP 479 + D + PTY + + D + ITH L +E+ + + L A P Sbjct: 199 NKDISPDPVILKSDGLPTYHLANVVDDYLMKITHVLRAQEWVSSGPLHVLLYKAFKWKPP 258 Query: 480 VQWEYGR-LNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCAR 538 + + +SKR L G+ PEAI N+ Sbjct: 259 IYCHLPMVMGNDGQKLSKRHGST----------------ALRQFIEDGYLPEAIINYVTL 302 Query: 539 VGVTVAQ 545 +G + Sbjct: 303 LGWSYDD 309 >6BRL-A nrPDB Length = 511 Score = 267 bits (683), Expect = 1e-71, Method: Composition-based stats. Identities = 71/336 (21%), Positives = 128/336 (38%), Gaps = 41/336 (12%) Query: 263 QVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMV 322 +VR RF P P G LH+G + +++ +AK N G LR +DT+ ++ I + + Sbjct: 11 KVRVRFAPSPTGPLHLGGVRTALYDYLFAKHNGGDFILRIEDTDTQRYVPGSEEYIMEAL 70 Query: 323 AWLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNT 370 W+G Y PY+ + D +D+ + ++++ AY+ EEL Sbjct: 71 EWIGMVPDESPKHGGPYAPYRQSERRDIYDR---YTEQILKTDYAYLAFDTPEELDQIRA 127 Query: 371 LPSPWRD---------RPMEESLLLFEAMRKGKFSEGEA-TLRMKLVMED-GKMDPVAYR 419 D + S+ L E K E +R K+ ++ ++ + Sbjct: 128 EFEARGDVFAYNYETRNRLRNSISLPEEEVKKLLEEKTPYVIRFKMPLDRIINLNDIIRG 187 Query: 420 VKYTPHHRTGDKWCI----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALD 475 + DK + PTY + + + D ITH + +E+ + + L A+ Sbjct: 188 KFSVNTNTLDDKVLVKNDGMPTYHFANIIDDHEMKITHVIRGEEWLPSMALHVLLYEAMG 247 Query: 476 VYCPVQWEYGRLNLHYAVVSKRKILQLVATGA------VRDWDDPRLFTLTALRRRGFPP 529 P E+ L+L K K+ + + D T R G+ P Sbjct: 248 WDAP---EFAHLSLILKPEGKGKLSKRDGDKFGFPVFPLNFTDSATGNTSAGYREEGYLP 304 Query: 530 EAINNFCARVGVTVAQTTMEPHLLEACVRD-VLNDT 564 EA N A +G + A E ++ +++ LN Sbjct: 305 EAFINMVAMLGWSPADNK-EIVSMDEMIKEFDLNKV 339 >2CV2-A nrPDB Length = 468 Score = 266 bits (679), Expect = 3e-71, Method: Composition-based stats. Identities = 74/319 (23%), Positives = 120/319 (37%), Gaps = 53/319 (16%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 V TR P P G H+G A FN+ +A+ N G +R +DT+ + I + Sbjct: 2 VVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRIEDTDRARYVPGAEERILAALK 61 Query: 324 WLGY---------TPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEEL--------- 365 WLG P+ S+ +A EL++RG AY + EEL Sbjct: 62 WLGLSYDEGPDVGGPHGPYRQSERLPLYQKYAEELLKRGWAYRAFETPEELEQIRKEKGG 121 Query: 366 ---KGHNTLP--SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRV 420 + N P + R R E ++ + R G +E + LR +V ++ ++ V Sbjct: 122 YDGRARNIPPEEAEERARRGEPHVIRLKVPRPGT-TEVKDELRGVVVYDNQEIPDVVLL- 179 Query: 421 KYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPV 480 K YPTY + + D + +T + +E+ + L A P Sbjct: 180 ----------KSDGYPTYHLANVVDDHLMGVTDVIRAEEWLVSTPIHVLLYRAFGWEAPR 229 Query: 481 QWEYGRL-NLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARV 539 + L N +SKRK + DW + GF PEA+ N+ + Sbjct: 230 FYHMPLLRNPDKTKISKRK------SHTSLDW----------YKAEGFLPEALRNYLCLM 273 Query: 540 GVTVAQTTMEPHLLEACVR 558 G ++ E LE ++ Sbjct: 274 GFSMPDGR-EIFTLEEFIQ 291 >2JA2-A nrPDB Length = 498 Score = 264 bits (674), Expect = 1e-70, Method: Composition-based stats. Identities = 69/304 (22%), Positives = 121/304 (39%), Gaps = 39/304 (12%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G H+G + FN+ YA+ G R +DT+ +++ + + A+ D + Sbjct: 7 VRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGTFVFRIEDTDAQRDSEESYLALLDALR 66 Query: 324 WLG------------YTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTL 371 WLG Y PY+ + ++ + + A L+ G AY EE++ + Sbjct: 67 WLGLDWDEGPEVGGPYGPYRQSQRAEIYRDVLA---RLLAAGEAYHAFSTPEEVEARHV- 122 Query: 372 PSPWRDRPMEESLL---LFEAMRKGKFSEGE-ATLRMKLV-----MEDGKMDPVAYRVKY 422 + R+ + L +A R +EG +R+++ D PV + Sbjct: 123 -AAGRNPKLGYDNFDRHLTDAQRAAYLAEGRQPVVRLRMPDDDLAWNDLVRGPVTFAAGS 181 Query: 423 TPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQW 482 P + P Y + D++ ITH L ++ L AL Sbjct: 182 VPDFAL-TRASGDPLYTLVNPCDDALMKITHVLRGEDLLPSTPRQLALHQALI------- 233 Query: 483 EYGRLNLHYAVVSKRKILQLVATGAVR-DWDDPRLFTLTALRRRGFPPEAINNFCARVGV 541 R+ + + + ++ G + DP+ L A R RGF PE + N+ A +G Sbjct: 234 ---RIGVAERIPKFAHLPTVLGEGTKKLSKRDPQ-SNLFAHRDRGFIPEGLLNYLALLGW 289 Query: 542 TVAQ 545 ++A Sbjct: 290 SIAD 293 >2CFO-A nrPDB Length = 492 Score = 263 bits (673), Expect = 1e-70, Method: Composition-based stats. Identities = 71/311 (22%), Positives = 113/311 (36%), Gaps = 32/311 (10%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR R P P G LHIG A+ FN+ YA+ G LR +DT+ E+ ++ I + + Sbjct: 2 VRVRLAPSPTGNLHIGTARTAVFNWLYARHRGGKFILRIEDTDRERSRPEYTENILEGLQ 61 Query: 324 WLGYTPYK-VTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEE 382 WLG T + + SD D L+ +GLAY C+ EEL+ P + Sbjct: 62 WLGLTWDEGPYFQSDRLDLYRQAIQTLLDKGLAYYCYCTPEELEALRAEQKAKGQAPRYD 121 Query: 383 S---LLLFEAMRKGKFSEGEATLRMKL--VMEDGKMDPVAYRVKYTPHHRTGDKW----- 432 + L E + + +R K+ + D V RV + GD Sbjct: 122 NRHRHLTPEEQAAFEAAGRTPVIRFKIEDDRQIEWQDLVRGRVSWQGADLGGDMVIARAA 181 Query: 433 ----CIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-L 487 YP Y+ + D IT + ++ L AL P L Sbjct: 182 PRGEIGYPLYNLVVVVDDIAMGITDVIRGEDHIGNTPKQILLYEALGATPPNFAHTPLIL 241 Query: 488 NLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTT 547 N +SKR + +++ R G+ A+ N+ +G + + Sbjct: 242 NSTGQKLSKR----------------DGVTSISDFRAMGYLAPALANYMTLLGWSPPEGV 285 Query: 548 MEPHLLEACVR 558 E L+ + Sbjct: 286 GELFTLDLAAK 296 >4G6Z-A nrPDB Length = 490 Score = 250 bits (639), Expect = 1e-66, Method: Composition-based stats. Identities = 64/297 (21%), Positives = 109/297 (36%), Gaps = 31/297 (10%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VRTRF P P G +H+G+ ++ + + +A+ G LR +DT+ E+ + AI + +A Sbjct: 26 VRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDVERSSQEAVDAILEGMA 85 Query: 324 WLGYT----PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRP 379 WLG PY D + ++ A ++ +GL Y C+ EEL ++P Sbjct: 86 WLGLDYDEGPYYQMQRMDRYREVLA---QMQEKGLVYPCYMSTEELDALRERQRAAGEKP 142 Query: 380 MEESLLLFE--AMRKGKFSEGEATLRMKLVMEDGK-MDPVAYRVKYTPHHRTGDKWC--- 433 + E + + LR + + D + D Sbjct: 143 RYDGTWRPEPGKVLPEPPAGVAPVLRFRNPLTGTVAWDDAVKGRVEISNEELDDLVVARP 202 Query: 434 -IYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNLHY 491 P Y++ + D ITH + + + AL PV LN Sbjct: 203 DGTPMYNFCVVVDDLDMGITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQG 262 Query: 492 AVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTM 548 +SKR ++ R G+ PEA+ N+ AR+G + + Sbjct: 263 EKMSKRHGAM----------------SVMGYRDAGYLPEAVLNYLARLGWSHGDAEI 303 >5H4V-A nrPDB Length = 488 Score = 248 bits (632), Expect = 9e-66, Method: Composition-based stats. Identities = 63/313 (20%), Positives = 109/313 (34%), Gaps = 27/313 (8%) Query: 265 RTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAW 324 RTRF P P G LHIG A+ + + A+ G LR +DT+ ++ AI + + W Sbjct: 25 RTRFAPSPTGYLHIGGARTALYCWLEARRRGGQFVLRIEDTDRQRSTQAAIDAILEAMQW 84 Query: 325 LGYT-PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEES 383 LG Y + + A +L+ +G AY ++ EEL +++P + Sbjct: 85 LGLGYDEGPIYQTQRVARYQEVAEQLLAQGKAYYAYETREELDAMREAAMAKQEKPRYDG 144 Query: 384 LLLFEAMRKGKFSEGEATLRMKLVMEDGKM--DPVAYRVKYTPHHRTGD---KWCIYPTY 438 + +R K + + D + R++ + PTY Sbjct: 145 AA--REQNLPYRDDPNRVIRFKNPIGGTVVFDDLIKGRIEIANSELDDMVIFRPDGLPTY 202 Query: 439 DYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNLHYAVVSKR 497 ++ + D IT + + + AL P L+ +SKR Sbjct: 203 NFAVVVDDWDMGITEVIRGDDHINNTPRQINIYAALGAPVPKFAHMPMILDEQGTKLSKR 262 Query: 498 KILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTM--EPHLLEA 555 V + G+ P A+ N+ AR+G + + LL+ Sbjct: 263 TGAADVMQ----------------YKDAGYLPHALINYLARLGWSHGDQELFTPQELLDL 306 Query: 556 CVRDVLNDTAPRA 568 +N A R Sbjct: 307 FDVKDVNSKAARL 319 >3AKZ-B nrPDB Length = 487 Score = 230 bits (586), Expect = 2e-60, Method: Composition-based stats. Identities = 57/299 (19%), Positives = 104/299 (34%), Gaps = 44/299 (14%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G LH+G A+ FN+ +A+ G LR +DT+ E+ ++ I + + Sbjct: 25 VRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSSREYEQQILESLR 84 Query: 324 WLGYTPYK---------VTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSP 374 W G + S+ + +A +L+ AY E+ Sbjct: 85 WCGLDWDEGPDIGGDFGPYRQSERLEIYREYAEKLVEDKRAYYVVYDKED---------- 134 Query: 375 WRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCI 434 P +E +E + K T++ K++ + + + D + Sbjct: 135 ----PSKELFTTYEYPHEYKEKGHPVTIKFKVLPGKTSFEDLLKGYMEFDNSTLEDFIIM 190 Query: 435 ----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNL 489 +PTY++ + D + I+H ++ + + A PV L Sbjct: 191 KSNGFPTYNFAVVVDDHLMRISHVFRGEDHLSNTPKQLMIYEAFGWEAPVFMHIPLILGS 250 Query: 490 HYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTM 548 +SKR ++ RR G A+ N+ A +G V + Sbjct: 251 DRTPLSKRHGAT----------------SVEHFRREGILSRALMNYLALLGWRVEGDEI 293 >3AL0-C nrPDB Length = 592 Score = 228 bits (582), Expect = 6e-60, Method: Composition-based stats. Identities = 57/299 (19%), Positives = 104/299 (34%), Gaps = 44/299 (14%) Query: 264 VRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVA 323 VR RF P P G LH+G A+ FN+ +A+ G LR +DT+ E+ ++ I + + Sbjct: 130 VRVRFAPSPTGHLHVGGARTALFNWMFARKEGGKFILRIEDTDTERSSREYEQQILESLR 189 Query: 324 WLGYTPYK---------VTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSP 374 W G + S+ + +A +L+ AY E+ Sbjct: 190 WCGLDWDEGPDIGGDFGPYRQSERLEIYREYAEKLVEDKRAYYVVYDKED---------- 239 Query: 375 WRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCI 434 P +E +E + K T++ K++ + + + D + Sbjct: 240 ----PSKELFTTYEYPHEYKEKGHPVTIKFKVLPGKTSFEDLLKGYMEFDNSTLEDFIIM 295 Query: 435 ----YPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNL 489 +PTY++ + D + I+H ++ + + A PV L Sbjct: 296 KSNGFPTYNFAVVVDDHLMRISHVFRGEDHLSNTPKQLMIYEAFGWEAPVFMHIPLILGS 355 Query: 490 HYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTM 548 +SKR ++ RR G A+ N+ A +G V + Sbjct: 356 DRTPLSKRHGAT----------------SVEHFRREGILSRALMNYLALLGWRVEGDEI 398 >4A91-A nrPDB Length = 298 Score = 142 bits (359), Expect = 4e-34, Method: Composition-based stats. Identities = 51/280 (18%), Positives = 88/280 (31%), Gaps = 27/280 (9%) Query: 259 ITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAI 318 +T Q RF P P+G LH G A ++ A+A G +R +D +P +E I Sbjct: 1 MTDTQYIGRFAPSPSGELHFGSLIAALGSYLQARARQGRWLVRIEDIDPPREVPGAAETI 60 Query: 319 CDMVAWLGYTP-YKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRD 377 + G V + S D L +GL+Y C ++ Sbjct: 61 LRQLEHYGLHWDGDVLWQSQRHDAYREALAWLHEQGLSYYCTCTRARIQSIGG------- 113 Query: 378 RPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYP- 436 + + R A +R++ + + + + + I+ Sbjct: 114 --IYDGHC-----RVLHHGPDNAAVRIRQQHPVTQFTDQLRGIIHADEKLAREDFIIHRR 166 Query: 437 ----TYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGR-LNLHY 491 Y+ + D + +T + + L P LN Sbjct: 167 DGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLFGWKVPDYIHLPLALNPQG 226 Query: 492 AVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEA 531 A +SK+ + G DPR + AL+ G EA Sbjct: 227 AKLSKQNHAPALPKG------DPRPVLIAALQFLGQQAEA 260 >3L9X-A nrPDB Length = 413 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 70/202 (34%), Gaps = 20/202 (9%) Query: 290 YAKANNGICFLRFDDTNPEKEEAKFFTAICD----MVAWLGYTPYKVTYASDYFDQLYAW 345 A+A + ++R EK E + F + LG PY+ +D F + + Sbjct: 99 IARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRR---F 155 Query: 346 AVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEESLLLFEAMRKG--KFSEGEATLR 403 ++++ +A V + + + + E+ L R G EG+ T Sbjct: 156 NIQMVEE-MAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGN 214 Query: 404 MKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIY--PTYDYTHCLCDSIEHITHSLCTKEFQ 461 M ++ + P + P +G IY P ++H +E T E Sbjct: 215 MA---DEPETKPSSTSGGLVPRGSSGMILIIYAHPYPHHSHANKRMLEQA----RTLEGV 267 Query: 462 ARRSSYFWLCNALDVYCPVQWE 483 RS Y L ++ + E Sbjct: 268 EIRSLYQ-LYPDFNIDIAAEQE 288 >2G36-A nrPDB Length = 340 Score = 37.0 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 21/67 (31%), Gaps = 7/67 (10%) Query: 272 PNGILHIGHAKAINFNFGYAKANNGICFLRFDD-------TNPEKEEAKFFTAICDMVAW 324 P G LHIGH N+ + CF D + + ++ + Sbjct: 21 PTGKLHIGHLVGALENWVKLQEEGNECFYFVADWHALTTHYDDVSKLKEYTRDLVRGFLA 80 Query: 325 LGYTPYK 331 G P K Sbjct: 81 CGIDPEK 87 >3FNR-A nrPDB Length = 464 Score = 35.9 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 12/32 (37%), Gaps = 3/32 (9%) Query: 271 EPNGILHIGHAKAINFN---FGYAKANNGICF 299 P G LHIGHA+ F A+ Sbjct: 40 NPTGPLHIGHARGAVFGDTLTRLARHLGYKFN 71 >5AH5-A nrPDB Length = 822 Score = 33.9 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 37/124 (29%), Gaps = 31/124 (25%) Query: 270 PEPNGILHIGHAKAINFNFGYAKANNGI------------CFLRFDD------TNPEKEE 311 P +G LHIGH + + A+ L ++ T+P K Sbjct: 40 PYTSGHLHIGHVRNYSMGDTLARMQIARGYSVLHPMGWDSFGLPAENAARKFGTHPAKFT 99 Query: 312 AKFFTAICDMVAWLGYT-----------PYKVTYASDYFDQLYAWAVELIRRGLAYVCHQ 360 ++ + LG+ P V F LY LI R YV Sbjct: 100 QDAIDSMKRSMMQLGFGYSWANELATCSPTYVLAQQKLFLDLYR--KGLIYRDDTYVYWD 157 Query: 361 RGEE 364 E+ Sbjct: 158 PVEQ 161 >2J5B-A nrPDB Length = 348 Score = 33.6 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 23/135 (17%), Positives = 48/135 (35%), Gaps = 18/135 (13%) Query: 232 HKPGENYKTPGYVVTPH--TMNLLKQHLEITGGQVRTRFPP-EPNGILHIGHAKAINFNF 288 H E+ T + T++ LKQ ++ G++ T + EP+G +HI A N Sbjct: 8 HTNNEHRLTQLLSIAEECETLDRLKQLVD--SGRIFTAYNGFEPSGRIHIAQALITVMNT 65 Query: 289 GYAKANNGICFLRFD------------DTNPEKEEAKFFTAICDMVAWLGYTPYKVTYAS 336 G + D N +E ++F + + + +AS Sbjct: 66 NNMIECGGQMIIYIADWFAKMNLKMNGDINKIRELGRYFIEVFKACG-INLDGTRFIWAS 124 Query: 337 DYFDQLYAWAVELIR 351 ++ ++ ++ Sbjct: 125 EFIASNPSYIERMLD 139 >4ARC-A nrPDB Length = 880 Score = 32.8 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 36/109 (33%), Gaps = 22/109 (20%) Query: 270 PEPNGILHIGHAKAINFNFGYAKANN--GICFLR----------------FDDTNPEKEE 311 P P+G LH+GH + A+ G L+ ++T P Sbjct: 62 PYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWT 121 Query: 312 AKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAV----ELIRRGLAY 356 + + + LG+ + + Y W EL ++GL Y Sbjct: 122 YDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVY 170 >3JXE-A nrPDB Length = 392 Score = 32.4 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 19/95 (20%) Query: 272 PNGILHIGHAKAINFNFGYAKANNGIC--FLRFDDTNPEK-----------EEAKFFTAI 318 P+G +HIGH F K L T+ EK + + I Sbjct: 82 PSGPMHIGH----IIPFFATKWLQEKFGVNLYIQITDDEKFLFKENLTFDDTKRWAYDNI 137 Query: 319 CDMVAWLGYTPYKVT-YASDYFDQLYAWAVELIRR 352 D++A +G+ P K + + F ++Y A+ + ++ Sbjct: 138 LDIIA-VGFDPDKTFIFQNSEFTKIYEMAIPIAKK 171 >1IQ0-A nrPDB Length = 592 Score = 32.4 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 32/148 (21%), Positives = 50/148 (33%), Gaps = 20/148 (13%) Query: 271 EPNGILHIGHAKAINFNFGYAK--ANNGICFL---RFDDTNPEKEEAKFFTAICDMVAWL 325 PN LH+GH + I A+ A G L DDT + E F + W Sbjct: 113 NPNKELHVGHLRNIALGDAIARILAYAGREVLVLNYIDDTGRQAAETLFALRHY-GLTWD 171 Query: 326 GYTPYKVTYASDY--------FDQLYAWAVELIRRGLAYVCHQRGEEL-KGHNTLPSPWR 376 G Y Y +++L E++ A + EE+ + + Sbjct: 172 GKEKYDHFAGRAYVRLHQDPEYERLQPAIEEVL---HALERGELREEVNRILLAQMATMH 228 Query: 377 DRPMEESLLLFE--AMRKGKFSEGEATL 402 LL++E +R G + A L Sbjct: 229 ALNARYDLLVWESDIVRAGLLQKALALL 256 >3IZO-F nrPDB Length = 581 Score = 32.0 bits (71), Expect = 0.97, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 593 PNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQH-VV 651 P +P D G VPF F+ F+E P G L +P+ + +++ + + Sbjct: 13 PVYPYDTETGPPTVPFLTPPFVSPNGFQESPP-GVLSLRLSEPLVTSNGMLALKMGNGLS 71 Query: 652 KGPSGCVESLEVTCRRADAGEKPKAFIHW-VSQPLMC 687 +G + S VT +K K+ I+ +S PL Sbjct: 72 LDEAGNLTSQNVTTVSPPL-KKTKSNINLEISAPLTV 107 >2ZUE-A nrPDB Length = 629 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 23/157 (14%), Positives = 46/157 (29%), Gaps = 25/157 (15%) Query: 261 GGQVRTRFPP-EPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIC 319 G +V P LH+GHA+ A+ LRF E E + + Sbjct: 118 GKKVIVEHTSVNPTKPLHMGHARNAILGDVMAR------ILRF--LGYEVEVQNYIDDL- 168 Query: 320 DMVAWLGYTPYKVTYASDYFDQLYAWAVELIRR-------GLAYVCHQRGEELKGHNTLP 372 + + + ++ + ++ GL YV Sbjct: 169 -GIQFAQVYWGYLRLKEEFERIMNELRERGLKDNPIDHALGLLYVEV-------NRRLED 220 Query: 373 SPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME 409 +P + + + + E+ E +R ++V Sbjct: 221 NPELENEIRDIMKKLESGELYGRKLAEEVVRAQMVTT 257 >5FAD-A nrPDB Length = 161 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 9/92 (9%) Query: 106 DFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMI 165 DF + VGV + E+I EA+ A I ++ + R G + ++ ++ Sbjct: 49 DFNVKKAVGVEINDERIREAL-ANIEKNG---VTGRASIVKG-----NFFEVDISEATVV 99 Query: 166 KNEVDMQVLHLLGPKLEADLEKKFKVAKARLE 197 + V +L PKLE +L+ +V E Sbjct: 100 TMFLLTNVNEMLKPKLEKELKPGTRVVSHEFE 131 >4R3U-A nrPDB Length = 584 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 548 MEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVP 607 +E + + D +TA R + + VI N D+++ P D T Q+ Sbjct: 450 IEQGWFQKQIADFAYETALRKQSGQKP--VIGVNRFVENEEDVKIEIHPYDNTTAERQIS 507 Query: 608 FAPIVFIERTD 618 V ER + Sbjct: 508 RTRRVRAERDE 518 >2P8B-A nrPDB Length = 369 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 24/49 (48%), Gaps = 2/49 (4%) Query: 78 SKKIHTEPQLSAALEYVRSHPLDPIDT--VDFERECGVGVIVTPEQIEE 124 SKKI T +L+ L++ + D + + G+G+ + + ++E Sbjct: 312 SKKIITSVELTGPLKFTKDIGNLHYDVPFIRLNEKPGLGIEINEDTLQE 360 >1IRX-A nrPDB Length = 523 Score = 29.7 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 41/269 (15%), Positives = 84/269 (31%), Gaps = 54/269 (20%) Query: 271 EPNGILHIGHAKAINFNF--GYAKANNGICFLRF---DDTNPEKEEAKFFTAICDMVAWL 325 P+G +H+G+ + + + G+A + G DD + ++ + +L Sbjct: 29 TPSGYVHVGNFRELFTAYIVGHALRDKGYEVRHIHMWDDYDRFRKVPRNVPQEWKD--YL 86 Query: 326 GY------TPY--KVTYASDYFDQLYAWAVEL-IRRGLAYVCH-----QRGEELKG---- 367 G P+ +YA + + +L I L Y + EE++ Sbjct: 87 GMPISEVPDPWGCHESYAEHFMRKFEEEVEKLGIEVDLLYASELYKRGEYSEEIRLAFEK 146 Query: 368 -------HNTLPSPWRDRPMEES-----LLLFEAMRKGKFSEGEATLRMKLVMEDGKMDP 415 N + P+ E+ + E R+ + E + ++K +G Sbjct: 147 RDKIMEILNKYREIAKQPPLPENWWPAMVYCPEHRREAEIIEWDGGWKVKYKCPEGHEGW 206 Query: 416 VAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYF----WLC 471 V R +W + ++H D K+ SSY + Sbjct: 207 VDIRSGNVK-----LRWRVDWPMRWSHFGVDFEPA------GKDHLVAGSSYDTGKEIIK 255 Query: 472 NALDVYCP--VQWEYGRLNLHYAVVSKRK 498 P + +E+ + +S K Sbjct: 256 EVYGKEAPLSLMYEFVGIKGQKGKMSGSK 284 >2I34-A nrPDB Length = 258 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 49/145 (33%), Gaps = 19/145 (13%) Query: 23 TLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLASRLRDTRRLSFLVSYIASKKIH 82 L NS A + I+KA L G L+ T + YI+++K + Sbjct: 70 VLDNSPHQAMSVKTGKGYPYKWDDWINKAEAEALPGSIDFLKYTESKGVDIYYISNRKTN 129 Query: 83 TEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERY 142 QL A ++ + I+ + E+ R +L+ + + Sbjct: 130 ---QLDATIKNLERVGAPQATKEH---------ILLQDPKEKG-----KEKRRELVSQTH 172 Query: 143 HFNMGLLMGEARAVLKWADGKMIKN 167 L G+ + DGK +K+ Sbjct: 173 DIV--LFFGDNLSDFTGFDGKSVKD 195 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.128 0.332 Lambda K H 0.267 0.0396 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,664,117 Number of Sequences: 36641 Number of extensions: 1072342 Number of successful extensions: 3065 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 19 Number of HSP's that attempted gapping in prelim test: 2816 Number of HSP's gapped (non-prelim): 84 length of query: 775 length of database: 10,336,785 effective HSP length: 105 effective length of query: 670 effective length of database: 6,489,480 effective search space: 4347951600 effective search space used: 4347951600 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 63 (28.9 bits)