BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P47895 (512 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5FHZ-A nrPDB 1057 0.0 4X2Q-A nrPDB 767 0.0 5AC0-A nrPDB 753 0.0 5AC2-A nrPDB 749 0.0 1O9J-A nrPDB 718 0.0 5L13-A nrPDB 694 0.0 1AG8-A nrPDB 692 0.0 4PXL-B nrPDB 513 e-145 5GT6-A nrPDB 492 e-139 4PZ2-A nrPDB 490 e-139 3RHO-A nrPDB 462 e-130 4O5H-A nrPDB 409 e-114 4QYJ-A nrPDB 405 e-113 4O6R-A nrPDB 402 e-112 4CAZ-A nrPDB 401 e-112 6B4R-B nrPDB 390 e-109 4V3F-A nrPDB 388 e-108 5IUV-A nrPDB 387 e-108 4GO4-A nrPDB 376 e-104 2D4E-A nrPDB 374 e-104 4MPY-A nrPDB 370 e-103 3IWJ-A nrPDB 370 e-103 3IWK-A nrPDB 361 e-100 1BPW-A nrPDB 360 1e-99 3R31-A nrPDB 357 5e-99 4I8P-A nrPDB 355 2e-98 4I8Q-A nrPDB 344 7e-95 4LIH-A nrPDB 335 3e-92 6QAO-A nrPDB 330 8e-91 3JZ4-A nrPDB 329 1e-90 5KLK-A nrPDB 327 6e-90 4F3X-A nrPDB 322 3e-88 6MVR-A nrPDB 311 5e-85 5J77-A nrPDB 306 1e-83 3I44-A nrPDB 306 1e-83 3U4J-A nrPDB 306 2e-83 3TY7-A nrPDB 305 3e-83 4U3W-A nrPDB 302 2e-82 4YWE-A nrPDB 301 4e-82 5EUY-A nrPDB 296 2e-80 1WNB-A nrPDB 293 2e-79 4V6H-A nrPDB 292 2e-79 3EK1-A nrPDB 289 2e-78 2HG2-A nrPDB 289 2e-78 3B4W-A nrPDB 289 2e-78 3RJL-A nrPDB 288 3e-78 4JZ6-A nrPDB 288 3e-78 6C43-A nrPDB 286 1e-77 3RHD-A nrPDB 285 3e-77 3QAN-A nrPDB 285 3e-77 6FK3-A nrPDB 276 1e-74 3K2W-A nrPDB 273 1e-73 5UR2-A nrPDB 271 4e-73 3R64-A nrPDB 262 3e-70 5X5U-A nrPDB 261 4e-70 5VBF-A nrPDB 257 7e-69 4DNG-A nrPDB 253 2e-67 2J5N-A nrPDB 252 3e-67 1T90-A nrPDB 250 1e-66 3RH9-A nrPDB 249 2e-66 2QE0-A nrPDB 245 3e-65 2W8P-A nrPDB 243 1e-64 3PRL-A nrPDB 243 2e-64 3ROS-A nrPDB 226 2e-59 4PXN-A nrPDB 226 2e-59 4OGD-A nrPDB 223 1e-58 3VZ0-A nrPDB 222 3e-58 2JG7-A nrPDB 219 3e-57 3EFV-A nrPDB 218 5e-57 3VZ3-A nrPDB 217 9e-57 1UXV-A nrPDB 213 1e-55 5N5S-A nrPDB 212 4e-55 5TJR-A nrPDB 209 2e-54 4X0T-A nrPDB 209 3e-54 4I3V-A nrPDB 205 3e-53 4ZZ7-A nrPDB 201 6e-52 4KNA-A nrPDB 200 1e-51 5U0M-A nrPDB 194 6e-50 5KF0-A nrPDB 194 9e-50 5JRY-A nrPDB 193 2e-49 4E4G-A nrPDB 187 8e-48 5J6B-A nrPDB 187 8e-48 4H7N-A nrPDB 183 1e-46 6DBB-A nrPDB 176 2e-44 3JU8-A nrPDB 163 1e-40 5UCD-A nrPDB 162 3e-40 3SZA-A nrPDB 160 2e-39 1AD3-A nrPDB 159 3e-39 3V9H-A nrPDB 158 5e-39 4OE4-A nrPDB 156 2e-38 4LGZ-A nrPDB 155 3e-38 4QGK-A nrPDB 148 5e-36 5NNO-A nrPDB 134 1e-31 4IDS-A nrPDB 130 1e-30 2Y53-A nrPDB 86 5e-17 6D97-A nrPDB 65 6e-11 3V4C-A nrPDB 62 4e-10 5DBV-A nrPDB 62 8e-10 5JFN-A nrPDB 56 3e-08 5UJU-A nrPDB 55 9e-08 1EZ0-A nrPDB 51 1e-06 3MY7-A nrPDB 48 9e-06 3K9D-A nrPDB 39 0.006 2DQ3-A nrPDB 36 0.052 4GHK-A nrPDB 31 1.3 1O20-A nrPDB 30 2.3 5Z0Q-C nrPDB 30 2.4 2HZK-A nrPDB 30 3.4 2ACV-A nrPDB 29 4.8 5ZCY-A nrPDB 29 5.0 5Y9F-A nrPDB 28 7.5 3AFG-A nrPDB 28 8.3 3FCR-A nrPDB 28 8.8 >5FHZ-A nrPDB Length = 529 Score = 1057 bits (2734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 512/512 (100%), Positives = 512/512 (100%) Query: 1 MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI 60 MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI Sbjct: 18 MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI 77 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 120 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM Sbjct: 78 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 137 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW 180 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW Sbjct: 138 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW 197 Query: 181 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV 240 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV Sbjct: 198 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV 257 Query: 241 GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE 300 GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE Sbjct: 258 GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE 317 Query: 301 CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK 360 CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK Sbjct: 318 CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK 377 Query: 361 QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL 420 QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL Sbjct: 378 QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL 437 Query: 421 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF 480 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF Sbjct: 438 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF 497 Query: 481 KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP 512 KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP Sbjct: 498 KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP 529 >4X2Q-A nrPDB Length = 504 Score = 767 bits (1980), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/491 (71%), Positives = 423/491 (86%) Query: 21 PRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQV 80 P P NLE+K+TKIFINNEW S+SG+ F NP+T EQ+CEV+E DK D+DKAV+AA++ Sbjct: 13 PSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARL 72 Query: 81 AFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT 140 AF GS WRR+DA RGRLL +LADLVERDRA LA +E+++ GKPFL AF++DL+G I+T Sbjct: 73 AFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT 132 Query: 141 LRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT 200 RY+AGWADKI G TIP D + FTRHEPIGVCG I PWNFPLLM WK+APALCCGNT Sbjct: 133 FRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNT 192 Query: 201 MVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTE 260 +V+KPAEQTPL+ALY+G+LIKEAGFPPGV+NI+PG+GPT GAAI+SH I+KIAFTGSTE Sbjct: 193 VVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTE 252 Query: 261 VGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRV 320 VGKL++EAA RSNLKRVTLELGGK+P I+ ADADLD AVE AHQGVFFNQGQCCTA SR+ Sbjct: 253 VGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRI 312 Query: 321 FVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLE 380 FVEE +Y EFVRRSVE AK+R VG PFD TEQGPQID+KQ++KILELI+SG EGAKLE Sbjct: 313 FVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLE 372 Query: 381 CGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLT 440 CGG + KG FI+PTVFS VTD+MRIAKEEIFGPVQ IL+FK+++EVI+RAN++D+GL Sbjct: 373 CGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLV 432 Query: 441 AAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEV 500 AAVFT +++KAL ++SA+++GTVWINCYNAL AQ+PFGGFKMSGNGRE+GE+ L EY+EV Sbjct: 433 AAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEV 492 Query: 501 KTVTIKLGDKN 511 KTVT+K+ KN Sbjct: 493 KTVTVKIPQKN 503 >5AC0-A nrPDB Length = 501 Score = 753 bits (1944), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/494 (71%), Positives = 420/494 (85%) Query: 18 PALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEA 77 P +P P+ NL+ K+TKIFINNEWH S SGKKF NP+T E++CEVEEGDK DVDKAV+A Sbjct: 7 PDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKA 66 Query: 78 AQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGC 137 A+ AFQ GSPWR +DA RGRLL++LADL+ERDR LA +E M+ GK F +A+ +DL GC Sbjct: 67 ARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLGGC 126 Query: 138 IRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCC 197 I+TLRY AGWADKIQG+TIP D N +TR EP+GVCG I PWNFPLLM +WK+ PAL C Sbjct: 127 IKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSC 186 Query: 198 GNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTG 257 GNT+V+KPAEQTPLTAL++GSLIKEAGFPPGVVNIVPG+GPT GAAISSH ++K+AFTG Sbjct: 187 GNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTG 246 Query: 258 STEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAA 317 STEVGKL+KEAA +SNLKRV+LELGGK+PCIV ADADLD AVE AHQGVF++QGQCC AA Sbjct: 247 STEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAA 306 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 SR+FVEE +Y EFVRRSVE AKK +G+P QGPQID++Q++KIL+LIESGKKEGA Sbjct: 307 SRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGA 366 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 KLECGG +KG FI+PTVFS+VTD+MRIAKEEIFGPVQ I+KFKS+++VIKRAN+T Y Sbjct: 367 KLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFY 426 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL+A +FT ++DKA+ ++SAL+SGTVW+NCY+ + AQ PFGGFKMSGNGRELGEY EY Sbjct: 427 GLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFHEY 486 Query: 498 TEVKTVTIKLGDKN 511 TEVKTVTIK+ KN Sbjct: 487 TEVKTVTIKISQKN 500 >5AC2-A nrPDB Length = 501 Score = 749 bits (1934), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/494 (70%), Positives = 419/494 (84%) Query: 18 PALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEA 77 P LP + +L++++TKIFINNEWH+S SGKKF NP+T E++C+VEEGDK DVDKAV+A Sbjct: 7 PDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKA 66 Query: 78 AQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGC 137 A+ AFQ GSPWR +DA RGRLL++LADL+ERDR LA +E+M+ GK + +A+ DL GC Sbjct: 67 ARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGC 126 Query: 138 IRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCC 197 I+TLRY AGWADKIQG+TIP D N +TRHEPIGVCG I PWNFPL+ML+WK+ PAL C Sbjct: 127 IKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSC 186 Query: 198 GNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTG 257 GNT+V+KPAEQTPLTAL++ SLIKEAGFPPGVVNIVPG+GPT GAAISSH I+K+AFTG Sbjct: 187 GNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTG 246 Query: 258 STEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAA 317 STEVGKL+KEAA +SNLKRVTLELGGK+PCIV ADADLD AVE AH GVF++QGQCC AA Sbjct: 247 STEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAA 306 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 SR+FVEE +Y EFVRRSVE AKK +G+P QGPQID++Q+DKIL+LIESGKKEGA Sbjct: 307 SRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGA 366 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 KLECGG +KG F++PTVFS VTD MRIAKEEIFGPVQ I+KFKS+++VIKRAN+T Y Sbjct: 367 KLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFY 426 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL+A VFTK++DKA+ ++SAL++GTVW+NCY + AQ PFGGFKMSGNGRELGEY EY Sbjct: 427 GLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEY 486 Query: 498 TEVKTVTIKLGDKN 511 TEVKTVT+K+ KN Sbjct: 487 TEVKTVTVKISQKN 500 >1O9J-A nrPDB Length = 501 Score = 718 bits (1854), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/494 (68%), Positives = 410/494 (82%) Query: 18 PALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEA 77 P LP P+ N++++ TK+FINNEWHES SGK F NP+T E+ICEVEE DK DVDKAV+A Sbjct: 7 PDLPAPLTNIKIQHTKLFINNEWHESVSGKTFPVFNPATEEKICEVEEADKEDVDKAVKA 66 Query: 78 AQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGC 137 A+ AFQ GSPWR +DA RG+L+++LADL+ERDR LA LE+++ GK F A+ +DL+ C Sbjct: 67 AREAFQMGSPWRTMDASERGQLIYKLADLIERDRLLLATLESINAGKVFASAYLMDLDYC 126 Query: 138 IRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCC 197 I+ LRY AGWADKIQG+TIP D +TRHEPIGVCG I PWN P+++L K+ PALCC Sbjct: 127 IKALRYCAGWADKIQGRTIPVDGEFFSYTRHEPIGVCGLIFPWNAPMILLACKIGPALCC 186 Query: 198 GNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTG 257 GNT+++KPAEQTPLTAL++ SLIKEAGFPPGVVNIVPG+GPT GAAISSH ++K+AFTG Sbjct: 187 GNTVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTG 246 Query: 258 STEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAA 317 STEVGK+++EAA++SNLKRVTLELG KNPCIV ADADLD AVE AHQGVF NQGQ C AA Sbjct: 247 STEVGKMIQEAAAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAA 306 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 S++FVEE +Y EFV+RSVE AKK G+P GPQI++ Q +KI+ELIESGKKEGA Sbjct: 307 SKLFVEEAIYDEFVQRSVERAKKYVFGNPLTPGVNHGPQINKAQHNKIMELIESGKKEGA 366 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 KLECGG +KG FI+PTVFS VTD+MRIAKEEIFGPVQ I+KFKS++EVIKRAN+T Y Sbjct: 367 KLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTYY 426 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL A VFTK+LDKA+ ++SAL++GTVW+NCY A AQ+P GGFKMSG+GRE+GEY + EY Sbjct: 427 GLVAGVFTKDLDKAVTVSSALQAGTVWVNCYLAASAQSPAGGFKMSGHGREMGEYGIHEY 486 Query: 498 TEVKTVTIKLGDKN 511 TEVKTVT+K+ +KN Sbjct: 487 TEVKTVTMKISEKN 500 >5L13-A nrPDB Length = 517 Score = 694 bits (1790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/493 (66%), Positives = 394/493 (79%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 A+P P + EV +IFINNEWH++ S K F T NPST E IC+V EGDK DVDKAV+AA Sbjct: 24 AVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAVKAA 83 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AFQ GSPWRR+DA RGRLL++LADL+ERDR LAALET+D GKP++ ++ +DL+ + Sbjct: 84 RAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLDMVL 143 Query: 139 RTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCG 198 + LRY+AGWADK GKTIP D + +TRHEP+GVCG I PWNFPLLM WKL PAL G Sbjct: 144 KCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATG 203 Query: 199 NTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 258 N +V+K AEQTPLTALY+ +LIKEAGFPPGVVNIVPGFGPT GAAI+SH ++K+AFTGS Sbjct: 204 NVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGS 263 Query: 259 TEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS 318 TE+G++++ AA SNLKRVTLELGGK+P I+ +DAD+D AVE AH +FFNQGQCC A S Sbjct: 264 TEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGS 323 Query: 319 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 R FV+E +Y EFV RSV AK R VG+PFD KTEQGPQ+D+ QF KIL I +GK+EGAK Sbjct: 324 RTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAK 383 Query: 379 LECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG 438 L CGG D+G FI+PTVF +V D M IAKEEIFGPV ILKFK+IEEV+ RAN++ YG Sbjct: 384 LLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYG 443 Query: 439 LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYT 498 L AAVFTK+LDKA L+ AL++GTVW+NCY+ AQ+PFGG+KMSG+GRELGEY L YT Sbjct: 444 LAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYT 503 Query: 499 EVKTVTIKLGDKN 511 EVKTVT+K+ KN Sbjct: 504 EVKTVTVKVPQKN 516 >1AG8-A nrPDB Length = 499 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 319/493 (64%), Positives = 396/493 (80%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 A+P P + EV + +IFINNEWH++ S K F T NPST + IC V EGDK DVD+AV+AA Sbjct: 6 AVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTVNPSTGDVICHVAEGDKADVDRAVKAA 65 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AFQ GSPWRR+DA RGRLL++LADL+ERDR LAALET+D GKP++ ++ +DL+ + Sbjct: 66 RAAFQLGSPWRRMDASERGRLLNRLADLIERDRTYLAALETLDNGKPYIISYLVDLDMVL 125 Query: 139 RTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCG 198 + LRY+AGWADK GKTIP D + +TRHEP+GVCG I PWNFPLLM WKL PAL G Sbjct: 126 KCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATG 185 Query: 199 NTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 258 N +V+K AEQTPLTALY+ +LIKEAGFPPGVVN++PGFGPT GAAI+SH ++K+AFTGS Sbjct: 186 NVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIASHEDVDKVAFTGS 245 Query: 259 TEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS 318 TEVG L++ AA +SNLKRVTLE+GGK+P I+ +DAD+D AVE AH +FFNQGQCC A S Sbjct: 246 TEVGHLIQVAAGKSNLKRVTLEIGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGS 305 Query: 319 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 R FV+E +Y+EFV RSV AK R VG+PFD +TEQGPQ+D+ QF K+L I+SGK+EG K Sbjct: 306 RTFVQEDIYAEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKVLGYIKSGKEEGLK 365 Query: 379 LECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG 438 L CGG A D+G FI+PTVF ++ D M IAKEEIFGPV ILKFKS+EEV+ RAN++ YG Sbjct: 366 LLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSMEEVVGRANNSKYG 425 Query: 439 LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYT 498 L AAVFTK+LDKA L+ AL++GTVW+NCY+ AQ+PFGG+K+SG+GRELGEY L YT Sbjct: 426 LAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGSGRELGEYGLQAYT 485 Query: 499 EVKTVTIKLGDKN 511 EVKTVT+++ KN Sbjct: 486 EVKTVTVRVPQKN 498 >4PXL-B nrPDB Length = 517 Score = 513 bits (1320), Expect = e-145, Method: Compositional matrix adjust. Identities = 241/484 (49%), Positives = 339/484 (70%), Gaps = 1/484 (0%) Query: 24 IRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQ 83 + +EV+FTK+FI+ ++ ++ SGK F T +P T E I + EGDK DVD AV+AA+ AF Sbjct: 29 VPKVEVRFTKLFIDGKFVDAVSGKTFETRDPRTGEVIASIAEGDKADVDLAVKAAREAFD 88 Query: 84 RGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 G PW R+ RGR+LH+ ADL++ LAAL+T+D GK F D+ G LRY Sbjct: 89 NG-PWPRMTGYERGRILHRFADLIDEHVEELAALDTVDAGKLFAVGKARDIPGAAHLLRY 147 Query: 144 FAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 +AG ADK+ G T+ + +T EP+GV G I PWN+P M +K+ PAL G +V+ Sbjct: 148 YAGAADKVHGATLKMAQRMHGYTLKEPVGVVGHIVPWNYPTTMFFFKVGPALAAGCAVVV 207 Query: 204 KPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGK 263 KPAEQTPL+AL+ L +EAG P GV+N+VPGFGPT GAA+++H ++K++FTGSTEVG+ Sbjct: 208 KPAEQTPLSALFYAHLAREAGVPAGVLNVVPGFGPTAGAAVAAHMDVDKVSFTGSTEVGR 267 Query: 264 LVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 LV AA+ SNLK V+LELGGK+P IV DADLD+AV + + N+G+ C A +R++V+ Sbjct: 268 LVMRAAAESNLKPVSLELGGKSPVIVFDDADLDMAVNLVNFATYTNKGEICVAGTRIYVQ 327 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 E +Y EFV+++ E A K VGDPF+ QGPQ+D+ Q++K+L I+ GK+EGA L GG Sbjct: 328 EGIYDEFVKKAAELASKSVVGDPFNPSVSQGPQVDKDQYEKVLRYIDIGKREGATLVTGG 387 Query: 384 SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 DKG +I+PT+F++V D+M IA++EIFGPV ++KFK++EEVI++AN+T YGL A + Sbjct: 388 KPCGDKGYYIEPTIFTDVKDDMTIAQDEIFGPVMALMKFKTVEEVIQKANNTRYGLAAGI 447 Query: 444 FTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 TKN+D A ++ ++ +G +WINCY A APFGG+KMSG G+++G AL +Y + KTV Sbjct: 448 VTKNIDVANTVSRSIRAGAIWINCYFAFDPDAPFGGYKMSGFGKDMGMDALDKYLQTKTV 507 Query: 504 TIKL 507 L Sbjct: 508 VTPL 511 >5GT6-A nrPDB Length = 508 Score = 492 bits (1266), Expect = e-139, Method: Compositional matrix adjust. Identities = 242/475 (50%), Positives = 318/475 (66%), Gaps = 2/475 (0%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K+FIN E+ + GK F T NP+T + + V E + D+D AV+AA+ AF+ G PW + Sbjct: 35 KMFINGEFVSAIGGKTFETYNPATEDVLAVVCEAQEEDIDAAVKAARSAFESG-PWAEMT 93 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R L+++LADL+E R LA LE +D GKP+ A D+ + RY+AGW KI Sbjct: 94 TAERAHLIYKLADLIEEHREELAQLEALDNGKPYQVALDDDISATVENYRYYAGWTTKII 153 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 G+TIP + + +TRHEP+GV G I PWNFPL+M WK+ AL G T+VLKPAEQTPL+ Sbjct: 154 GQTIPISKDYLNYTRHEPVGVVGQIIPWNFPLVMSSWKMGAALATGCTIVLKPAEQTPLS 213 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 LY L KEAGFP GVVN VPGFGP GAAI +H I+K+AFTGST GK + ++ Sbjct: 214 LLYAAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKVAFTGSTVTGKYIMRQSAEM 273 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 +K VTLELGGK+P I+ DADL+ A+ A QG+ +N GQ C+A SRVFV + Y V Sbjct: 274 -IKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQNCSAGSRVFVHRKHYETVVD 332 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLF 392 V+ A +G + +TE GP + +KQ +++L IE GKKEGA + GG +KG F Sbjct: 333 ALVKMANNVKLGAGMEKETEMGPLVSKKQQERVLNYIEQGKKEGATVAAGGERALEKGYF 392 Query: 393 IKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKAL 452 +KPTVF++VTD+M I KEEIFGPV +L F S EEVI+RAN++ YGL A V+T+N+ Sbjct: 393 VKPTVFTDVTDDMTIVKEEIFGPVVVVLPFDSTEEVIERANNSSYGLAAGVWTQNIKTGH 452 Query: 453 KLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 ++A+ L++GTVWIN YN A APFGG+K SG GRELG YAL YTEVK+V + + Sbjct: 453 QVANKLKAGTVWINDYNLENAAAPFGGYKQSGIGRELGSYALDNYTEVKSVWVNI 507 >4PZ2-A nrPDB Length = 534 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 248/483 (51%), Positives = 329/483 (68%), Gaps = 4/483 (0%) Query: 28 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 87 E++FTK+FIN + ++ SG+ F T +P T I V E DK DVD AV AA+ AF G Sbjct: 47 EIRFTKLFINGSFVDAVSGRTFDTRDPRTGGVIASVAEADKEDVDLAVRAARAAFDHGE- 105 Query: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147 W R+ RGR++ +LADLVE LAALE++D GK +D+ +LRYFAG Sbjct: 106 WPRMSGSERGRIMARLADLVEEHAGELAALESLDAGKHPAVTRAVDVGNAAGSLRYFAGA 165 Query: 148 ADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 ADKI G+T+ T EP+GV G I PWNFP M K+APAL G +V+KPAE Sbjct: 166 ADKIHGETLKMPGQFQGHTLREPLGVAGVIIPWNFPSTMFAVKVAPALAAGCALVVKPAE 225 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 QTPL+ALYL L K+AG P GV+N+VPGFGPT GAA++SH ++ ++FTGSTEVG+L+ + Sbjct: 226 QTPLSALYLAQLAKQAGVPDGVINVVPGFGPTAGAALASHMDVDMVSFTGSTEVGRLIMK 285 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 A++ SNLK V LELGGK+P IV DADLD+AVE A FFN+G+ C AASRV+V+E+VY Sbjct: 286 ASAESNLKPVYLELGGKSPLIVFDDADLDMAVELAVGASFFNKGEACVAASRVYVQERVY 345 Query: 328 SEFVRRSVEYAKKRPVGDPF-DVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS-- 384 F R E + VGDPF D + +QGPQ+D+ Q++++L I+ GK+EGA L GG Sbjct: 346 DRFEERLAERMRSWVVGDPFSDPRADQGPQVDKAQYERVLSYIDHGKREGATLLTGGRPC 405 Query: 385 AMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 A E KG +I+PTVF+ V ++M IAKEEIFGPV ++KFK++EE I RAN T YGL A V Sbjct: 406 APEGKGYYIEPTVFTNVKEDMIIAKEEIFGPVMCLMKFKTVEEAIARANDTRYGLGAGVV 465 Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 T++LD A ++ ++ +G VW+NCY A+ + PFGG KMSG G++ G +AL +Y VK+V Sbjct: 466 TRDLDVANRVVRSVRAGVVWVNCYFAMGSDCPFGGRKMSGFGKDEGMHALDKYLAVKSVV 525 Query: 505 IKL 507 L Sbjct: 526 TPL 528 >3RHO-A nrPDB Length = 517 Score = 462 bits (1190), Expect = e-130, Method: Compositional matrix adjust. Identities = 226/480 (47%), Positives = 323/480 (67%), Gaps = 7/480 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 ++FI E+ +++ K + T NP+ IC+V DVDKAV AA+ AF+ G W +++ Sbjct: 38 QLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGL-WGKIN 96 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 A RGRLL++LAD++E+ + LA +E +D G + A + I+T RYFAGW DKIQ Sbjct: 97 ARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCDKIQ 156 Query: 153 GKTIPTD----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQ 208 G TIP + + + T+ EP+GVCG + PWN+PL+ML WK A L GNT+V+KPA+ Sbjct: 157 GATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKPAQV 216 Query: 209 TPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEA 268 TPLTAL L +AG P GVVNI+PG G VG +S HP + KI FTGSTEVGK + ++ Sbjct: 217 TPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHIMKS 276 Query: 269 ASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYS 328 + SN+K+V+L+LGGK+P I+ AD DL+ AV+ VFFN+G+ C AA R+FVEE +++ Sbjct: 277 CALSNVKKVSLQLGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEESIHN 336 Query: 329 EFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED 388 +FV++ VE +K +G+P + T GPQ + K++E + G KEGA L CGG+ + Sbjct: 337 QFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQVPR 396 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFK--SIEEVIKRANSTDYGLTAAVFTK 446 G F +PTVF++V D+M IAKEE FGP+ I +F ++ V+ RAN+T++GL + VFT+ Sbjct: 397 PGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRANATEFGLASGVFTR 456 Query: 447 NLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 +++KAL ++ L++GTV+IN YN APFGGFK SG G++LGE AL EY +KTVT + Sbjct: 457 DINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEAALNEYLRIKTVTFE 516 >4O5H-A nrPDB Length = 511 Score = 409 bits (1050), Expect = e-114, Method: Compositional matrix adjust. Identities = 222/494 (44%), Positives = 302/494 (61%), Gaps = 8/494 (1%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 AL R K ++ I EW ++ SG++ NP+ I V E D+ DV +AV AA Sbjct: 18 ALLDATRAFLAKPKQMLIGAEWSDAASGRQLDVVNPADGTVIARVPEADERDVQQAVAAA 77 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AF G PWR R RL+ LADL+E + LA +E++D GKP + A +D+ Sbjct: 78 RRAFDAG-PWRTAKTTDRERLMLVLADLIEANARELAEIESLDNGKPVMVAQGLDVAMAA 136 Query: 139 RTLRYFAGWADKIQGKTIPT------DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLA 192 + RY AGWA KI+G I D + +TR EP+GV GAI PWNFPLLM WK+A Sbjct: 137 QCFRYMAGWATKIEGSVIDAGMPYLPDSEIFAYTRKEPVGVVGAIIPWNFPLLMAAWKIA 196 Query: 193 PALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINK 252 PAL G T+VLKPAE TPL+AL LG LI+ AGFP GVVNIV G+G T GAA+S P+I+K Sbjct: 197 PALATGCTVVLKPAEDTPLSALRLGELIQAAGFPDGVVNIVTGYGHTAGAALSRDPRIDK 256 Query: 253 IAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQ 312 IAFTGST+ GK + AA N+ R++LELGGK+P IV D DLD A + +FFNQGQ Sbjct: 257 IAFTGSTQTGKTIGHAA-LDNMTRMSLELGGKSPVIVLPDVDLDKAAQGVANAIFFNQGQ 315 Query: 313 CCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESG 372 CTA SR ++ +V+ + R + A +G D T+ GP + KQ +++ I+SG Sbjct: 316 VCTAGSRAYIHSKVFDGVIERVAKIAASLKIGPGMDPATQIGPLVSAKQRERVCGYIDSG 375 Query: 373 KKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRA 432 EGA+ GG A++ G F++PTV + T MR+ +EEIFGPV + F ++ ++ A Sbjct: 376 FGEGARAAAGGRAIDGPGFFVEPTVLVDTTQAMRVVREEIFGPVLVAMPFDDVDTAVQLA 435 Query: 433 NSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEY 492 N T YGL A++++ +L KL + +GTVW+NC++ L PFGG K SG GRELG Sbjct: 436 NDTPYGLGASIWSNDLSAIHKLVPRIAAGTVWVNCHSLLDNALPFGGMKQSGFGRELGRA 495 Query: 493 ALAEYTEVKTVTIK 506 + +YTE K+V + Sbjct: 496 VIDQYTESKSVMMN 509 >4QYJ-A nrPDB Length = 516 Score = 405 bits (1042), Expect = e-113, Method: Compositional matrix adjust. Identities = 212/481 (44%), Positives = 298/481 (61%), Gaps = 10/481 (2%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 ++ I +W ++SGK NP+T + + EV +GD DV+ AVE+A A R WRR+ Sbjct: 36 QMLIGGQWVSAQSGKTLNVYNPATGDILTEVPDGDVEDVNAAVESA-AATLRSDTWRRMP 94 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 +R R+L +LADL+E LA LET++ GK +++ +++ + LRY AGWA K+ Sbjct: 95 PSARERILLRLADLLEVHGDELARLETLNNGKLLIYSKLMEVGASAQWLRYMAGWATKLT 154 Query: 153 GKTI------PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 206 G T+ P + T+ P+GV AI PWNFPLLM VWK+APAL CGNT+VLKPA Sbjct: 155 GSTLDLSLPLPPEVRSRASTQRVPVGVVAAIIPWNFPLLMAVWKIAPALACGNTVVLKPA 214 Query: 207 EQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 E+TPLTAL L L EAG P G +N+V G G T G A+ HP++ K+AFTGSTEVG+++ Sbjct: 215 EETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDALVRHPKVAKVAFTGSTEVGRIIG 274 Query: 267 EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQV 326 A RS LK V+LELGGK+P IV AD D A E A +FFN GQ CTA SR++V E + Sbjct: 275 SACGRS-LKAVSLELGGKSPVIVLADCDPQEAAEGAAAAIFFNHGQVCTAGSRLYVHESI 333 Query: 327 YSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS-A 385 Y + ++R + VG + GP + +K + +L I +G ++GA L CGG+ A Sbjct: 334 YEDVIQRLAVIGESIVVGSGLEQGVHMGPMVSKKHHENVLRHIRNGIEDGADLICGGTEA 393 Query: 386 MEDKGLFIKPTVFSEV-TDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 +G F+KPT+F+ ++R+ +E+FGPV F I EV+ AN + YGL A+++ Sbjct: 394 PCAQGFFVKPTIFANREKKDIRLLSQEVFGPVLVATPFSDIAEVVNEANRSVYGLGASIW 453 Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 T +L AL++ LE+GTVW+N +N + PFGGFK SG GRE G A+ YT +++ Sbjct: 454 TNDLSAALRINDELEAGTVWVNTHNMVDPNLPFGGFKDSGVGREHGAAAIEHYTTTRSLV 513 Query: 505 I 505 I Sbjct: 514 I 514 >4O6R-A nrPDB Length = 496 Score = 402 bits (1032), Expect = e-112, Method: Compositional matrix adjust. Identities = 200/485 (41%), Positives = 291/485 (60%), Gaps = 8/485 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 T++FI+ + ++ NP I ++ DVD AV+AA AF W + Sbjct: 11 TQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAF---PAWSAM 67 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 A RGRLL +LAD +E + LA LE++DTG P + +D+ RYF G ADK+ Sbjct: 68 PAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKL 127 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 QG IP D + + + PIGV G I PWNFPL+ WK+ PAL GNT+VLKP+E TPL Sbjct: 128 QGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPL 187 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L + L+ E GFP GVVNIVPG+G T G ++ HP + KIAFTGST G+ + E AS+ Sbjct: 188 STLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVE-ASQ 246 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 NLKRV LELGGK IV DA+LD A+ A +F NQGQ C A SR+ + E++ F+ Sbjct: 247 GNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFL 306 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED--- 388 R V A +G+P D TE GP ++ D++L ++ +++G ++ GGSA +D Sbjct: 307 ERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPAL 366 Query: 389 -KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G +++PT+ R+A+EE+FGP +L+F S +E + AN+T+YGL + ++T + Sbjct: 367 ANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTND 426 Query: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 L +A ++A+ +++G WINCY + +PFGG SG GRE+G A+ +YTE ++V + + Sbjct: 427 LSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNV 486 Query: 508 GDKNP 512 P Sbjct: 487 DGNVP 491 >4CAZ-A nrPDB Length = 490 Score = 401 bits (1031), Expect = e-112, Method: Compositional matrix adjust. Identities = 204/481 (42%), Positives = 286/481 (59%), Gaps = 7/481 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K++I + E+ SG F T NP+ E + +V+ + DV++AV Q A + W + Sbjct: 8 KLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAV---QSAVEGQKVWAAMT 64 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 A+ R R+L + D++ LAALET+DTGKP +D+ L Y+AG I+ Sbjct: 65 AMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGLVPAIE 124 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 G+ IP + +TR EP+GV I WN+P+ + +WK APAL GN M+ KP+E TPLT Sbjct: 125 GEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSEVTPLT 184 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 AL L + EAG P GV N++ G G VG ++ HP I KI+FTG T GK V +AS S Sbjct: 185 ALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMASASSS 244 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 +LK VT+ELGGK+P I+ DADLD A + A FF+ GQ CT +RVF+ + F Sbjct: 245 SLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQARFEA 304 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED---- 388 + +E ++ +GDP D T GP + + +L IESGK + A+L CGG + D Sbjct: 305 KVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVTDGAFG 364 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 KG ++ PTVF++ D+M I +EEIFGPV IL + +E I+RAN T+YGL A V T++L Sbjct: 365 KGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGVVTQDL 424 Query: 449 DKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 +A + LE+G WIN + A+ P GG+K SG GRE G LA YT +K+V ++LG Sbjct: 425 ARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSVQVELG 484 Query: 509 D 509 D Sbjct: 485 D 485 >6B4R-B nrPDB Length = 497 Score = 390 bits (1003), Expect = e-109, Method: Compositional matrix adjust. Identities = 208/478 (43%), Positives = 293/478 (61%), Gaps = 4/478 (0%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 + F+N E+ + SG+ F +P + +V D D ++AV+ A+ AF G+ W RL Sbjct: 21 RAFVNGEYSNAASGETFDCLSPVDGRFLAKVASCDLADAEQAVKVARNAFDSGA-WSRLA 79 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R + + + ADL+ + LA LET+D GKP + ID+ +LR+ A DKI Sbjct: 80 PAKRKQTMIRFADLLLENAEELALLETLDMGKPISDSLHIDVASAANSLRWSAEAIDKIY 139 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 + T + EP+GV AI PWNFPLLM WKL PAL GN+++LKP+E++PLT Sbjct: 140 DEVAATPHAELGLVTREPVGVVAAIVPWNFPLLMSCWKLGPALATGNSVILKPSEKSPLT 199 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 A+ + L EAG P GV N++PG+G TVG A++ H ++ + FTGST++ K + A S Sbjct: 200 AIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHMDVDTLVFTGSTKIAKQLMVYAGES 259 Query: 273 NLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 N+KRV LE GGK+P IV ADA DL A E A + FNQG+ CTA SR+ VE + +F+ Sbjct: 260 NMKRVWLEAGGKSPNIVFADAPDLKAAAEAAAGAIAFNQGEVCTAGSRLLVERSIKDKFL 319 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG--SAMEDK 389 +E K G+P D +T G +D +Q + +L IE+G +GAKL GG + E Sbjct: 320 PLVIEALKGWKPGNPLDPETNVGALVDTQQMNTVLSYIEAGHNDGAKLVAGGKRTLEETG 379 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 G +++PT+F VT+ M+IA+EEIFGPV +++F+ EE ++ AN T YGL AAV+T NL Sbjct: 380 GTYVEPTIFDGVTNAMKIAREEIFGPVLSVIEFEDAEEAVRIANDTPYGLAAAVWTSNLS 439 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 KA A AL +G+VW+N Y+ APFGGFK SGNGR+ +A +YTE+K IKL Sbjct: 440 KAHLTAKALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELKATWIKL 497 >4V3F-A nrPDB Length = 497 Score = 388 bits (996), Expect = e-108, Method: Compositional matrix adjust. Identities = 210/502 (41%), Positives = 294/502 (58%), Gaps = 24/502 (4%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 A P P R L FI+ EW E + NPST E I ++ DV+ AV AA Sbjct: 2 AFPIPARQL-------FIDGEWREPIKKNRIPVINPSTEEIIGDIPAATAEDVEVAVVAA 54 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AF+R + W R L +A + + LET+D+GKPF A +D++ Sbjct: 55 RRAFRRNN-WSATSGAHRATYLRAIAAKITEKKDHFVKLETIDSGKPFDEAV-LDIDDVA 112 Query: 139 RTLRYFAGWADKIQGK-----TIPTDDNVVCFTRH---EPIGVCGAITPWNFPLLMLVWK 190 YFAG A+ + GK T+P + F H +P+GV G I+PWN+PLLM WK Sbjct: 113 SCFEYFAGQAEALDGKQKAPVTLPMER----FKSHVLRQPLGVVGLISPWNYPLLMATWK 168 Query: 191 LAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQI 250 +APAL G T VLKP+E +T L G + E G PPGV+NI+ G GP GA + SHP + Sbjct: 169 IAPALAAGCTAVLKPSELASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDV 228 Query: 251 NKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQ 310 +KIAFTGS+ G V +A++ +K VTLELGGK+P +V D D+D VE G F+ Sbjct: 229 DKIAFTGSSATGSKVMASAAQL-VKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTN 287 Query: 311 GQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIE 370 GQ C+A SR+ V E + +EFV + V++ K + DPF+ GP I + Q+DKI++ I Sbjct: 288 GQICSATSRLLVHESIAAEFVDKLVKWTKNIKISDPFEEGCRLGPVISKGQYDKIMKFIS 347 Query: 371 SGKKEGAKLECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEV 428 + K EGA + GGS E KG +I+PT+ ++++ +M+I KEE+FGPV + F S +E Sbjct: 348 TAKSEGATILYGGSRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTFSSEDEA 407 Query: 429 IKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRE 488 I AN T+YGL AAVF+ +L++ ++ ALE G VW+NC + QAP+GG K SG GRE Sbjct: 408 IALANDTEYGLAAAVFSNDLERCERITKALEVGAVWVNCSQPCFVQAPWGGIKRSGFGRE 467 Query: 489 LGEYALAEYTEVKTVTIKLGDK 510 LGE+ + Y +K VT + D+ Sbjct: 468 LGEWGIQNYLNIKQVTQDISDE 489 >5IUV-A nrPDB Length = 497 Score = 387 bits (995), Expect = e-108, Method: Compositional matrix adjust. Identities = 207/486 (42%), Positives = 294/486 (60%), Gaps = 5/486 (1%) Query: 25 RNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR 84 +NL+++ + FI E+ + SG+ F +P + +V D D +AVE+A+ AF Sbjct: 14 QNLKIE-GRAFIQGEYTAAASGETFDCISPVDGRLLAKVASCDAADAQRAVESARSAFDS 72 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 G+ W RL R + + A L+E++ LA LET+D GKP + +D+ G R L + Sbjct: 73 GA-WSRLAPAKRKATMIRFAGLLEQNAEELALLETLDMGKPISDSLGVDIPGGARALSWS 131 Query: 145 AGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 DK+ + T + + EP+GV AI PWNFPL+M WKL PAL GN++VLK Sbjct: 132 GEAIDKLYDEVAATPHDQLGLVTREPVGVVAAIVPWNFPLMMACWKLGPALSTGNSVVLK 191 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKL 264 P+E++PLTA+ + L EAG P GV+N++PG+G TVG A++ H ++ + FTGST++ K Sbjct: 192 PSEKSPLTAIRIAQLAIEAGIPAGVLNVLPGYGHTVGKALALHMDVDTVVFTGSTKIAKQ 251 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 + A SN+KRV LE GGK+P IV ADA DL A + A + FNQG+ CTA SR+ VE Sbjct: 252 LMIYAGESNMKRVWLEAGGKSPNIVFADAPDLQAAADSAASAIAFNQGEVCTAGSRLLVE 311 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 + F+ +E G+P D T G +D +Q + +L I +G +GA+L GG Sbjct: 312 RSIKDRFLPMVIEALGTWKPGNPLDPATNVGALVDTQQMNTVLSYIAAGHTDGARLVAGG 371 Query: 384 SAM--EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTA 441 + E G +++PT+F V + MRIA+EEIFGPV +L F + EE I+ AN T YGL A Sbjct: 372 KQILQETGGTYVEPTIFDGVNNAMRIAQEEIFGPVLSVLTFDTAEEAIQIANDTPYGLAA 431 Query: 442 AVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 AV+T NL KA A AL +G+VW+N Y+ APFGGFK SGNGR+ +A +YTE+K Sbjct: 432 AVWTANLSKAHLTARALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELK 491 Query: 502 TVTIKL 507 + IKL Sbjct: 492 STWIKL 497 >4GO4-A nrPDB Length = 495 Score = 376 bits (965), Expect = e-104, Method: Compositional matrix adjust. Identities = 200/483 (41%), Positives = 292/483 (60%), Gaps = 9/483 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 +++I+ + ++ +G +P I + + DVD AV AA+ AF W L Sbjct: 3 NQLYIDGRFVDAVAGGTIDVVSPHDGSLITRIAAAEAADVDLAVAAAKRAF---PAWSAL 59 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 A RGRLL +LAD +E LA LE+++TG P + +D+ RYF G ADKI Sbjct: 60 GAAERGRLLLKLADRIEECSEELAQLESLNTGHPIRDSRGLDVPRTAACFRYFGGMADKI 119 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 +G IP D + + + +PIGV I PWNFPL+ WK+ PAL GNT+V+KP+E TPL Sbjct: 120 EGSVIPVDAGFLNYVQRKPIGVVAQIVPWNFPLMFTSWKMGPALAAGNTIVIKPSEITPL 179 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L + L+ E GFP GVVN+VPG+G T G A++ H + KIAFTGST G+ + E AS+ Sbjct: 180 STLRIVELMTEVGFPKGVVNVVPGYGHTAGQALAEHLDVGKIAFTGSTATGRRIVE-ASK 238 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 SNLKR+ LELGGK IV DA+++ AV A +F NQGQ C A SR+ + + + +F+ Sbjct: 239 SNLKRIQLELGGKGANIVFEDANIEAAVNGAAWAIFHNQGQACIAGSRLILHKDIADQFL 298 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK-- 389 R + AK +GDP D +TE GP + D++L I+ ++G K+ GG A +DK Sbjct: 299 ERFIALAKSIRLGDPMDPETEMGPLTSALRRDRVLSYIDIAIEQGGKVLAGGKAPDDKAL 358 Query: 390 --GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G +++PTV E R+ +EE+FGP +++F S EE + AN+T+YGL + ++T+N Sbjct: 359 ANGFYVEPTVV-EAKPQDRVCQEEVFGPFVTVVRFSSDEEALAIANNTEYGLGSGLWTQN 417 Query: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 L +A K+A A+ +G WINCY + +PFGG SG GRE+G A+ +YTE ++V + + Sbjct: 418 LARAHKMAHAIHAGMCWINCYKRVSPGSPFGGVGQSGYGREMGFEAIHDYTEARSVWVNV 477 Query: 508 GDK 510 K Sbjct: 478 DAK 480 >2D4E-A nrPDB Length = 515 Score = 374 bits (960), Expect = e-104, Method: Compositional matrix adjust. Identities = 203/492 (41%), Positives = 303/492 (61%), Gaps = 15/492 (3%) Query: 25 RNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR 84 R L+ + FI E+ S+SG+ F + +P+T E + G + +VD+A +AA AFQR Sbjct: 20 RRLKERPALHFIAGEFVPSESGETFPSLDPATNEVLGVAARGGEREVDRAAKAAHEAFQR 79 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 W R A R R L ++A+L+E+ LA +E +D G+ L + ++ Sbjct: 80 ---WSRTKAKERKRYLLRIAELIEKHADELAVMECLDAGQ-VLRIVRAQVARAAENFAFY 135 Query: 145 AGWADK-IQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 A +A+ ++ +T P D + + +T P G G ITPWN PL++ W++APAL GNT+VL Sbjct: 136 AEYAEHAMEDRTFPVDRDWLYYTVRVPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVL 195 Query: 204 KPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGK 263 KPAE +P TA L ++KEA PPGV N+V GFG GAA+ +HP + + TG TE GK Sbjct: 196 KPAEWSPFTATKLAEILKEADLPPGVFNLVQGFGEEAGAALVAHPLVPLLTLTGETETGK 255 Query: 264 LVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 +V A+ +LKR++ ELGGK+P +V ADADL+ A++ +F G+ CTA+SR+ VE Sbjct: 256 IVMRNAA-DHLKRLSPELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVE 314 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 E+++ +FV + VE A+ VG P D +TE GP I + ++L +E+GK+EGA+L GG Sbjct: 315 EKIFEDFVGKVVERARAIRVGHPLDPETEVGPLIHPEHLQRVLGYVEAGKREGARLLVGG 374 Query: 384 SAME--------DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 + +G ++ PTVF ++M+IA+EEIFGPV + FK EE +++AN T Sbjct: 375 ERAKTSFRGEDLSRGNYLLPTVFVG-ENHMKIAQEEIFGPVLVAIPFKDEEEALRKANDT 433 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL A VFT++L++A +LA LE+G V++N +N + PFGG K SG+ RE G YAL Sbjct: 434 KYGLAAYVFTRDLERAHRLALELEAGMVYLNSHNVRHLPTPFGGVKGSGDRREGGTYALD 493 Query: 496 EYTEVKTVTIKL 507 YT++KT+ + L Sbjct: 494 FYTDLKTIALPL 505 >4MPY-A nrPDB Length = 520 Score = 370 bits (951), Expect = e-103, Method: Compositional matrix adjust. Identities = 199/484 (41%), Positives = 294/484 (60%), Gaps = 13/484 (2%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 +I+ EW ES + NP +E I V EG K D ++A+ AA+ AF+ G W + A Sbjct: 36 YIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAFESGE-WSQETAE 94 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 +RG+ + +AD ++ R LA LET+DTGK L + D++ YFAG ADK G+ Sbjct: 95 TRGKKVRAIADKIKEHREALARLETLDTGKT-LEESYADMDDIHNVFMYFAGLADKDGGE 153 Query: 155 TI--PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 I P D + EP+GV ITPWN+PLL WK+APAL G ++V+KP+E TPLT Sbjct: 154 MIDSPIPDTESKIVK-EPVGVVTQITPWNYPLLQASWKIAPALATGCSLVMKPSEITPLT 212 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 + + L++E GFP G +N++ G G VG +S H +++ ++FTG E GK + + A+ + Sbjct: 213 TIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIETGKHIMKNAA-N 271 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 N+ + LELGGKNP I+ DAD +LAV+ A G +F+ GQ C+A SR+ V+ + +F + Sbjct: 272 NVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRILVQNSIKDKFEQ 331 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME----D 388 ++ KK +G+ FD TE GP I + +KI ++ K EGA + GG + Sbjct: 332 ALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAVGGKRPDRDDLK 391 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 GLF +PTV + +MRI +EE+FGPV + F++ +E I+ AN + YGL AVF+K++ Sbjct: 392 DGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIYGLAGAVFSKDI 451 Query: 449 DKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 KA ++A+ L+ GTVWIN ++ +AQAP+GG+K SG GRELG+ L EY K + L Sbjct: 452 GKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEYLVSKHI---LT 508 Query: 509 DKNP 512 + NP Sbjct: 509 NTNP 512 >3IWJ-A nrPDB Length = 503 Score = 370 bits (950), Expect = e-103, Method: Compositional matrix adjust. Identities = 207/497 (41%), Positives = 291/497 (58%), Gaps = 25/497 (5%) Query: 20 LPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQ 79 +P P R L FIN +W K+ NP+T+ I ++ K DVD AV AA+ Sbjct: 3 IPIPTRQL-------FINGDWKAPVLNKRIPVINPATQNIIGDIPAATKEDVDVAVAAAK 55 Query: 80 VAFQR--GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGC 137 A R G+ W R R L +A V + LA LE++D GKP A + D++ Sbjct: 56 TALTRNKGADWATASGAVRARYLRAIAAKVTEKKPELAKLESIDCGKPLDEAAW-DIDDV 114 Query: 138 IRTLRYFAGWADKIQGK-----TIPTDDNVVCFTRH---EPIGVCGAITPWNFPLLMLVW 189 Y+A A+K+ + ++P D F H EPIGV G ITPWN+P+LM W Sbjct: 115 AGCFEYYADLAEKLDARQKAPVSLPMD----TFKSHVLREPIGVVGLITPWNYPMLMATW 170 Query: 190 KLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQ 249 K+APAL G +LKP+E LT L LG + KE G PPGV+NI+ G GP GA +++HP Sbjct: 171 KVAPALAAGCAAILKPSELASLTCLELGEICKEVGLPPGVLNILTGLGPEAGAPLATHPD 230 Query: 250 INKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFN 309 ++K+AFTGS+ G + AA++ +K V+LELGGK+P +V D DLD A E A G F+ Sbjct: 231 VDKVAFTGSSATGSKIMTAAAQL-VKPVSLELGGKSPLVVFEDVDLDKAAEWAIFGCFWT 289 Query: 310 QGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELI 369 GQ C+A SR+ + E + +EF+ R V++ K + DP + GP + + Q++KIL+ + Sbjct: 290 NGQICSATSRLILHESIATEFLNRIVKWIKNIKISDPLEEGCRLGPVVSEGQYEKILKFV 349 Query: 370 ESGKKEGAKLECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEE 427 + K EGA + GGS E KG FI+PT+ ++VT NM+I +EE+FGPV + F + EE Sbjct: 350 SNAKSEGATILTGGSRPEHLKKGFFIEPTIITDVTTNMQIWREEVFGPVLCVKTFSTEEE 409 Query: 428 VIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGR 487 I AN T YGL AAV + +L++ ++ A ++G VW+NC + QAP+GG K SG GR Sbjct: 410 AIDLANDTVYGLGAAVISNDLERCERVTKAFKAGIVWVNCSQPCFTQAPWGGVKRSGFGR 469 Query: 488 ELGEYALAEYTEVKTVT 504 ELGE+ L Y VK VT Sbjct: 470 ELGEWGLDNYLSVKQVT 486 >3IWK-A nrPDB Length = 503 Score = 361 bits (927), Expect = e-100, Method: Compositional matrix adjust. Identities = 201/493 (40%), Positives = 284/493 (57%), Gaps = 12/493 (2%) Query: 27 LEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR-- 84 + V ++FI+ EW K+ NPST I ++ K DVD AV+AA+ A R Sbjct: 3 ITVSSRQLFIDGEWRVPILNKRIPNINPSTENIIGDIPAATKEDVDLAVDAAKRAISRKN 62 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 G W R R L +A ++ + L LE++D GKP A DL+ + Y+ Sbjct: 63 GRDWSAASGSLRARYLRAIAAKIKEKKDELGKLESIDCGKPLEEAL-ADLDDVVACFEYY 121 Query: 145 AGWADKIQGK-----TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGN 199 AG A+++ K ++P D + EPIGV ITPWN+P LM WK+APAL G Sbjct: 122 AGLAEELDSKQKAPISLPMD-TFKSYILKEPIGVVALITPWNYPFLMATWKIAPALAAGC 180 Query: 200 TMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 +LKP+E +T L LG + KE G P GV+NIV G G GA+++SHP ++KI+FTGS+ Sbjct: 181 AAILKPSELASVTCLELGEICKEVGLPRGVLNIVTGLGHEAGASLASHPDVDKISFTGSS 240 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319 G + A++ +K V+LELGGK+P +V D DLD E G FF GQ C+A SR Sbjct: 241 ATGSKIMTTAAQL-VKPVSLELGGKSPIVVFEDVDLDKVAEWTVFGCFFTNGQICSATSR 299 Query: 320 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL 379 + V E + EFV + V++A+ + DP + GP + + Q+ K+L I S K EGA + Sbjct: 300 LIVHESIAVEFVDKLVKWAENIKISDPLEEGCRLGPIVSEAQYKKVLNCISSAKSEGATI 359 Query: 380 ECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 GG E KG F++PT+ ++VT +M+I +EE+FGPV + F + EE I AN T Y Sbjct: 360 LTGGRRPEHLKKGYFVEPTIITDVTTSMQIWREEVFGPVLAVKTFSTEEEAINLANDTHY 419 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL +AV + +L++ +L+ AL++G VWINC + QAP+GG K SG GRELGE+ L Y Sbjct: 420 GLGSAVMSNDLERCERLSKALQAGIVWINCAQPSFIQAPWGGIKRSGFGRELGEWGLENY 479 Query: 498 TEVKTVTIKLGDK 510 VK VT D+ Sbjct: 480 LSVKQVTRYTSDE 492 >1BPW-A nrPDB Length = 503 Score = 360 bits (923), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 179/462 (38%), Positives = 278/462 (60%), Gaps = 12/462 (2%) Query: 54 PSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRAT 113 P+T +C++ +VD+AV++AQ A+ + W ++ + R R++ + A ++ R Sbjct: 43 PATGRVLCQMVPCGAEEVDQAVQSAQAAYLK---WSKMAGIERSRVMLEAARIIRERRDN 99 Query: 114 LAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGV 173 +A LE ++ GK A + D++ + + Y+AG A + G+ I +TR EP+GV Sbjct: 100 IAKLEVINNGKTITEAEY-DIDAAWQCIEYYAGLAPTLSGQHIQLPGGAFAYTRREPLGV 158 Query: 174 CGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIV 233 C I WN+P ++ WK APAL CGN +V KP+ TP+T + L + EAG P G+VN+V Sbjct: 159 CAGILAWNYPFMIAAWKCAPALACGNAVVFKPSPMTPVTGVILAEIFHEAGVPVGLVNVV 218 Query: 234 PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA 293 G G G+ + HP + K++FTGS GK V E ++++ +K VTLELGGK+P ++ D Sbjct: 219 QG-GAETGSLLCHHPNVAKVSFTGSVPTGKKVMEMSAKT-VKHVTLELGGKSPLLIFKDC 276 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQ 353 +L+ AV A F QGQ CT +RVFV+ ++ +F+ V+ K VGDP +T Sbjct: 277 ELENAVRGALMANFLTQGQVCTNGTRVFVQREIMPQFLEEVVKRTKAIVVGDPLLTETRM 336 Query: 354 GPQIDQKQFDKILELIESGKKEGAKLECGGSAME------DKGLFIKPTVFSEVTDNMRI 407 G I + Q DK+L + KKEGA++ CGG + G F+ P V D+M Sbjct: 337 GGLISKPQLDKVLGFVAQAKKEGARVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTC 396 Query: 408 AKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC 467 KEEIFGPV +L F + EEV++RAN+T +GL + VFT+++ +A ++A+ LE+GT +IN Sbjct: 397 VKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDISRAHRVAANLEAGTCYINT 456 Query: 468 YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGD 509 Y+ + PFGG+KMSG GRE G+ + Y+++KTV +++GD Sbjct: 457 YSISPVEVPFGGYKMSGFGRENGQATVDYYSQLKTVIVEMGD 498 >3R31-A nrPDB Length = 517 Score = 357 bits (917), Expect = 5e-99, Method: Compositional matrix adjust. Identities = 190/478 (39%), Positives = 281/478 (58%), Gaps = 10/478 (2%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 FI+ ++ E +G F + P+T E I ++ V++A+ +A+ A + W + + Sbjct: 18 FIDGDYVEDNTGTPFESIFPATGEMIAKLHAATPAIVERAIASAKRAQKE---WAAMSPM 74 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWA-DKIQG 153 +RGR+L + AD++ L+ LET+DTGKP D +F G A + G Sbjct: 75 ARGRILKRAADIMRERNDALSTLETLDTGKPIQETIVADPTSGADAFEFFGGIAPSALNG 134 Query: 154 KTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213 IP + +T+ P+GVC I WN+P + WK APAL GN MV KP+E TPL A Sbjct: 135 DYIPLGGDF-AYTKRVPLGVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSENTPLGA 193 Query: 214 LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSN 273 L + ++ EAG P G+ N++ G T G + +HP + K++ TGS G+ V AA+ + Sbjct: 194 LKIAEILIEAGLPKGLFNVIQGDRDT-GPLLVNHPDVAKVSLTGSVPTGRKVAAAAA-GH 251 Query: 274 LKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRR 333 LK VT+ELGGK+P IV DAD++ AV A G F++ GQ C+ +RVFV+++ + F+ Sbjct: 252 LKHVTMELGGKSPMIVFDDADIESAVGGAMLGNFYSSGQVCSNGTRVFVQKKAKARFLEN 311 Query: 334 SVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG---SAMEDKG 390 + +GDP D T GP + + Q +K+L IE GK EGA L GG + + +G Sbjct: 312 LKRRTEAMILGDPLDYATHLGPLVSKAQQEKVLSYIEKGKAEGATLITGGGIPNNVAGEG 371 Query: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450 +++PTVF++VTD+M IA+EEIFGPV +L F +EV+ RAN+T++GL VFT +L + Sbjct: 372 AYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDDEDEVLARANATEFGLAGGVFTADLAR 431 Query: 451 ALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 A ++ LE+GT+WIN YN + PFGG K SG GRE AL Y+E+KTV + G Sbjct: 432 AHRVVDGLEAGTLWINTYNLCPVEIPFGGSKQSGFGRENSAAALEHYSELKTVYVSTG 489 >4I8P-A nrPDB Length = 520 Score = 355 bits (912), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 198/491 (40%), Positives = 287/491 (58%), Gaps = 12/491 (2%) Query: 29 VKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR--GS 86 V ++F++ EW G++ NP+T I E+ G DVD AV AA+ A +R G Sbjct: 22 VPLRQLFVDGEWRPPAQGRRLPVVNPTTEAHIGEIPAGTAEDVDAAVAAARAALKRNRGR 81 Query: 87 PWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAG 146 W R R + L +A V + LA LE +D GKP+ A + D++ YFA Sbjct: 82 DWARAPGAVRAKYLRAIAAKVIERKPELAKLEALDCGKPYDEAAW-DMDDVAGCFEYFAD 140 Query: 147 WADKIQGK-----TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTM 201 A+ + + ++P + C R EPIGV G ITPWN+PLLM WK+APAL G T Sbjct: 141 QAEALDKRQNSPVSLPME-TFKCHLRREPIGVVGLITPWNYPLLMATWKIAPALAAGCTA 199 Query: 202 VLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEV 261 VLKP+E +T L L + KE G P GV+NIV G GP GA +S+HP ++K+AFTGS E Sbjct: 200 VLKPSELASVTCLELADICKEVGLPSGVLNIVTGLGPDAGAPLSAHPDVDKVAFTGSFET 259 Query: 262 GKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVF 321 GK + +A+ +K VTLELGGK+P +V D D+D AVE G F+ GQ C+A SR+ Sbjct: 260 GKKIMASAA-PMVKPVTLELGGKSPIVVFDDVDIDKAVEWTLFGCFWTNGQICSATSRLL 318 Query: 322 VEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLEC 381 + ++ +F R V +AK V DP + GP + + Q++KI + I + K +GA + Sbjct: 319 IHTKIAKKFNERMVAWAKNIKVSDPLEEGCRLGPVVSEGQYEKIKKFISNAKSQGATILT 378 Query: 382 GG--SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 GG A +KG FI+PT+ +++T +M I +EE+FGPV + +F + +E I+ AN T YGL Sbjct: 379 GGVRPAHLEKGFFIEPTIITDITTSMEIWREEVFGPVLCVKEFSTEDEAIELANDTQYGL 438 Query: 440 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTE 499 AV + + ++ +L+ +++G +W+NC + QAP+GG K SG GRELGE + Y Sbjct: 439 AGAVISGDRERCQRLSEEIDAGCIWVNCSQPCFCQAPWGGNKRSGFGRELGEGGIDNYLS 498 Query: 500 VKTVTIKLGDK 510 VK VT + D+ Sbjct: 499 VKQVTEYISDE 509 >4I8Q-A nrPDB Length = 514 Score = 344 bits (882), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 186/489 (38%), Positives = 283/489 (57%), Gaps = 14/489 (2%) Query: 25 RNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR 84 RN+ + +++I EW E + NP+T E I ++ DVD AVEAA+ A R Sbjct: 17 RNVPIPRRQLYIGGEWREPVKKNRIPIINPATEEIIGDIPAATAEDVDIAVEAARKAIAR 76 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLH--AFFIDLEGCIRTLR 142 W R + L +A V ++ LA LE++D+GK A D+ GC Sbjct: 77 DD-WGSTTGAQRAKYLRAIAAKVLEKKSVLATLESLDSGKTLYESAADMDDVAGC---FE 132 Query: 143 YFAGWADKIQGKTIP----TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCG 198 Y+AG A+ + + + D+ + EP+GV G ITPWN+PLLM +WK+APAL G Sbjct: 133 YYAGLAEALDSRRMTPVNLNSDSYKSYVLREPLGVVGLITPWNYPLLMAIWKVAPALAAG 192 Query: 199 NTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 258 +LKP+E +T L LG + +E G P G +NI+ G GP G ++SHP ++KI+FTGS Sbjct: 193 CAAILKPSELASITCLELGEICREIGLPSGALNILTGLGPEAGGPLASHPHVDKISFTGS 252 Query: 259 TEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADAD-LDLAVECAHQGVFFNQGQCCTAA 317 G + AA++ +K V+L LGGK+P +V D D LD+A E G+F N GQ C+A Sbjct: 253 GPTGSKIMTAAAQL-VKPVSLALGGKSPIVVFDDIDNLDIAAEWTLFGIFANTGQVCSAT 311 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 SR+ V+E + S F+ R +++ K + DP + + GP + Q++K+L+ I + K EGA Sbjct: 312 SRLIVQENIASAFMDRLLKWTKNIKISDPLEEDCKLGPVVSAGQYEKVLKFISNAKSEGA 371 Query: 378 KLECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 + CGG + KG +++PT+ ++V +M I KEE+FGPV + FK+ E+ I+ AN T Sbjct: 372 TILCGGERPQHLKKGYYVQPTIITDVNTSMEIWKEEVFGPVLCVKTFKTEEQAIELANDT 431 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL AAV +K++ + + A ++G +WINC + + P+GG K SG GR+LG++ L Sbjct: 432 KYGLGAAVMSKDVKRCERFTKAFQTGIIWINCSQPTFNELPWGGKKRSGFGRDLGKWGLE 491 Query: 496 EYTEVKTVT 504 + +K VT Sbjct: 492 NFLNIKQVT 500 >4LIH-A nrPDB Length = 504 Score = 335 bits (858), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 200/486 (41%), Positives = 295/486 (60%), Gaps = 9/486 (1%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRG 85 +LE++ + FI+ ++ G+ F +P + +V + + DV+ AV AA+ AF G Sbjct: 23 SLEIE-GRAFIDGASRDAHGGRTFDCVSPIDGRVLAKVADCGEADVNAAVAAARRAFDAG 81 Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 W L+ +R +L + A L+ L+ LET+D GKP +D+ G + +FA Sbjct: 82 V-WAGLNPRARKAVLLRWAALMREHLDELSLLETLDAGKPIGDTTTVDVPGAAYCVEWFA 140 Query: 146 GWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKP 205 DK+ G+ P D ++V EP+GV A+ PWNFP+LM WK PAL GN++VLKP Sbjct: 141 EAIDKVGGEVAPADHHLVGLVTREPVGVVAAVVPWNFPILMAAWKFGPALAAGNSVVLKP 200 Query: 206 AEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLV 265 +E++PLTA+ + L EAG P GV N+VPG G G ++ H ++ IAFTGST VGKL+ Sbjct: 201 SEKSPLTAIRVAQLAFEAGIPAGVFNVVPGAGEP-GKLLALHRDVDCIAFTGSTAVGKLI 259 Query: 266 KEAASRSNLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + A++SNLKR LELGGK+P IV D DLD A + A +F+N G+ CTA SR+ V Sbjct: 260 MQYAAQSNLKRAWLELGGKSPNIVLPDCPDLDRAAQTAAGAIFYNMGEMCTAGSRLLVHR 319 Query: 325 QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS 384 + F+ + V A+ G+P D G +D Q +++L IE+G+ EG +L GG+ Sbjct: 320 DIKDAFIEKLVAAARAYVPGNPLDPSVSMGAIVDGIQLERVLGYIEAGRGEG-RLVTGGA 378 Query: 385 AM--EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 + E G +++PTVF EV + +IA+EEIFGPV ++ F ++E ++ AN T+YGL AA Sbjct: 379 RVNAETGGFYVEPTVF-EVKPDAKIAREEIFGPVLSVIVFDDVDEAVRIANDTEYGLAAA 437 Query: 443 VFTKNLDKALKLASALESGTVWINCYN-ALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 V+T NL A ++ L +GTVW+NCY+ PFGG+K SGNGR+ +AL +YTE+K Sbjct: 438 VWTSNLTTAHDVSRRLRAGTVWVNCYDEGGDMNFPFGGYKQSGNGRDKSLHALEKYTELK 497 Query: 502 TVTIKL 507 + I+L Sbjct: 498 STLIRL 503 >6QAO-A nrPDB Length = 508 Score = 330 bits (847), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 173/462 (37%), Positives = 270/462 (58%), Gaps = 12/462 (2%) Query: 54 PSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRAT 113 P+T I + +V+ AV+ A+ AF+ W + + R R+L + A ++ Sbjct: 48 PATGRVIATFTCSGEKEVNLAVQNAKAAFKI---WSQKSGMERCRILLEAARIIREREDE 104 Query: 114 LAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGV 173 +A +E ++ GK A +D++ + L Y+AG A + G+ I +TR EP+GV Sbjct: 105 IATMECINNGKSIFEAR-LDIDISWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGV 163 Query: 174 CGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIV 233 C I WN+P + WK APAL CGN MV KP+ TP++AL L + EAG PPG+ N+V Sbjct: 164 CVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVSALLLAEIYSEAGVPPGLFNVV 223 Query: 234 PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA 293 G G G + HP + K++FTGS G + E +++ +K VTLELGGK+P I+ +D Sbjct: 224 QG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAK-GIKPVTLELGGKSPLIIFSDC 281 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQ 353 D++ AV+ A F QGQ C +RVFV++++ +F V+ ++ +GDP T Sbjct: 282 DMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTEEVVKQTQRIKIGDPLLEDTRM 341 Query: 354 GPQIDQKQFDKILELIESGKKEGAKLECGGSAM--ED----KGLFIKPTVFSEVTDNMRI 407 GP I++ +++L ++ K++GAK+ CGG ED G +++P V + D+M Sbjct: 342 GPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPKLKDGYYMRPCVLTNCRDDMTC 401 Query: 408 AKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC 467 KEEIFGPV IL F + EV++RAN T +GL A VFT+++ +A ++ + L++GT +IN Sbjct: 402 VKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTRDIQRAHRVVAELQAGTCFINN 461 Query: 468 YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGD 509 YN + PFGG+K SG GRE G + Y+++KTV +++GD Sbjct: 462 YNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGD 503 >3JZ4-A nrPDB Length = 481 Score = 329 bits (844), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 185/476 (38%), Positives = 267/476 (56%), Gaps = 10/476 (2%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 IN EW ++ +G+ NP+ +++ V + + A++AA A WR L A Sbjct: 13 LINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRAL---PAWRALTAK 69 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 R +L +L+ + LA L T++ GKP A ++ + +FA +I G Sbjct: 70 ERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKG-EISYAASFIEWFAEEGKRIYGD 128 Query: 155 TIP---TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 TIP D ++ +PIGV AITPWNFP M+ K PAL G TMVLKPA QTP Sbjct: 129 TIPGHQADKRLIVI--KQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPF 186 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 +AL L L AG P GV N+V G VG ++S+P + K++FTGSTE+G+ + E ++ Sbjct: 187 SALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAK 246 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 ++K+V+LELGG P IV DADLD AVE A F N GQ C A+R++V++ VY F Sbjct: 247 -DIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFA 305 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 + + K +GD D GP ID+K K+ E I ++GA++ CGG A E G Sbjct: 306 EKLQQAMSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGN 365 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 F +PT+ +V N +++KEE FGP+ P+ +FK +VI +AN T++GL A + ++L + Sbjct: 366 FFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRV 425 Query: 452 LKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 ++ ALE G V IN APFGG K SG GRE +Y + +Y E+K + I L Sbjct: 426 FRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCIGL 481 >5KLK-A nrPDB Length = 520 Score = 327 bits (839), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 177/478 (37%), Positives = 263/478 (55%), Gaps = 23/478 (4%) Query: 45 SGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLA 104 S FA NP + I +V E D V++AV AAQ A + PW +L R L+H++A Sbjct: 51 SASSFANINPVNGKLISDVFEADAKQVNEAVVAAQNALK--GPWGKLSVQDRAALIHKIA 108 Query: 105 DLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTD----- 159 D ++ A E DTG+P A +D+ I R FA A KT TD Sbjct: 109 DGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLA-----KTSHTDLFEMS 163 Query: 160 ----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALY 215 + +T +P+GV G I+PW+ PLL+ WK+APAL CGNT+V KP+E++P +A Sbjct: 164 TSDGSGALNYTVRKPLGVIGVISPWDLPLLLFTWKVAPALACGNTVVAKPSEESPSSATL 223 Query: 216 LGSLIKEAGFPPGVVNIVPGFGP-TVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNL 274 L ++ +AG PPGV N++ GFG + G ++ HP I+ + FTG ++ G + +A + + Sbjct: 224 LAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKAVA-DGV 282 Query: 275 KRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRS 334 K V+ ELGGKN +V ADADLD A+E + F N GQ C + RV+V ++ EFV Sbjct: 283 KEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFDEFVSGL 342 Query: 335 VEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA-----MEDK 389 A++ VG P GP I DK+L EGA + GG D+ Sbjct: 343 KVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKFNDERDQ 402 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 G +++PT+++ ++D R EEIFGPV I F +EVI R N ++YGL A++T NL Sbjct: 403 GAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAIWTTNLS 462 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 +A +++ + G VW+N + + PFGG K+SG GRE G +++ Y+++ + IK+ Sbjct: 463 RAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANICIKI 520 >4F3X-A nrPDB Length = 498 Score = 322 bits (825), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 173/461 (37%), Positives = 261/461 (56%), Gaps = 13/461 (2%) Query: 53 NPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRA 112 NP T I ++ E +D AV+AA+ AF W + R L ++AD +E++ Sbjct: 46 NPRTGAGIIDLAEASHAQIDAAVDAAERAF---VGWSQTTPAERSNALLKIADAIEKEAD 102 Query: 113 TLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ----GKTIPTDDNVVCFTRH 168 AALE ++ GKP +L I R+FAG + G+ +P +++ R Sbjct: 103 EFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNLHAPAAGEYLPGHTSMI---RR 159 Query: 169 EPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPG 228 +PIG+ G+I PWN+PL+M+ WKLAPA+ GNT+V KP+EQTPLTAL L LI + P G Sbjct: 160 DPIGIVGSIAPWNYPLMMMAWKLAPAIGGGNTVVFKPSEQTPLTALKLARLIADI-LPEG 218 Query: 229 VVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCI 288 VVN++ G G TVG A+ +HP++ ++ TG GK V AA+++ +KR LELGGK P I Sbjct: 219 VVNVITGRGETVGNALINHPKVGMVSITGDIATGKKVLAAAAKT-VKRTHLELGGKAPVI 277 Query: 289 VCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFD 348 V DADL+ V ++N GQ CTAA R++ E +Y + V D Sbjct: 278 VYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIYEKLVADLTSAVSTIRYNLDDD 337 Query: 349 VKTEQGPQIDQKQFDKILELIE-SGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRI 407 + E GP I ++Q D++ +E + ++ ++ GG D+G F +PTV + T I Sbjct: 338 TENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTGSDEGFFFQPTVVAGATQEDEI 397 Query: 408 AKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC 467 + E+FGPV + +F ++ + AN +DYGL ++V+TK++ KA++ AS L+ G WIN Sbjct: 398 VRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTKDISKAMRAASRLQYGCTWINT 457 Query: 468 YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 + L + P GG K SG G+++ YAL +YT V+ + I G Sbjct: 458 HFMLTNEMPHGGIKQSGYGKDMSVYALEDYTAVRHIMINHG 498 >6MVR-A nrPDB Length = 767 Score = 311 bits (796), Expect = 5e-85, Method: Compositional matrix adjust. Identities = 187/470 (39%), Positives = 266/470 (56%), Gaps = 24/470 (5%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 FI W + G FAT NP+T + + +V + + V+AA A ++ P D Sbjct: 36 FIGGAW--TAPGDLFATVNPATGQTLAQVSQATQ----ADVDAAVKAARKAQPAWAKDGA 89 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 +R R+L+ LA L+++ A LET+D GKP A ID+ R + AG+A ++ G Sbjct: 90 ARARVLYALARLLQKHARLFAVLETLDNGKPIREARDIDVPLAQRHFYHHAGYA-QLMGT 148 Query: 155 TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTAL 214 +P P+GVCG + PWNFPLLML WK+APAL GNT+VLKPAE TPLTAL Sbjct: 149 EMPD---------RAPLGVCGQVIPWNFPLLMLAWKIAPALAMGNTVVLKPAEWTPLTAL 199 Query: 215 YLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNL 274 + +AG P GVVNIV G G VG I + Q++K+AFTGST VG+ ++EA + + Sbjct: 200 LFADICGQAGVPAGVVNIVTGDG-AVGEMIVT-AQVDKVAFTGSTAVGRRIREATAGTG- 256 Query: 275 KRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRS 334 K ++LELGGK P +VC DAD+D AVE ++FNQGQ C A SR+ V+E + F + Sbjct: 257 KALSLELGGKGPYVVCDDADIDSAVEGLVDAIWFNQGQVCCAGSRLLVQEGIADVFHAKL 316 Query: 335 VEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIK 394 +GDP D + G + Q ++ +++ + +G + A G + Sbjct: 317 RARMDSLRIGDPLDKCIDIGAMVHPDQLARVRDMV-AANTDGEVYQTAVPA----GCYYP 371 Query: 395 PTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKL 454 PT+ S + + ++EIFGPV F++ E ++ AN+T YGL A+V+++N++ AL L Sbjct: 372 PTLISGLAPASPLMQQEIFGPVLVSTTFRTPAEAVEIANNTAYGLAASVWSENVNLALDL 431 Query: 455 ASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 A L +G VWIN N + A APFGG + SG GRE G LA YT T Sbjct: 432 APKLVAGIVWINGTNMMDAAAPFGGVRESGFGREGGWEGLAGYTRPAIAT 481 Score = 72.4 bits (176), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 67/248 (27%), Positives = 103/248 (41%), Gaps = 14/248 (5%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 + K++I + G A P + + ++ D+ AVEA A S W Sbjct: 501 RTAKLYIGGKQTRPDGGYSRAVYGPKGK-LLGHASLSNRKDLRNAVEAMNAA----SGWS 555 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R R ++L+ + + + A TGK ++ I L A WAD Sbjct: 556 RTTGHLRAQILYFIGENLSARADEFANRIKDMTGKDGK----AEVAASIDRLFSAAAWAD 611 Query: 150 KIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 K G+ V EP+G G + P PLL LV +APA+ GN + L +E Sbjct: 612 KYDGQVKGVPLRGVALAMKEPVGKIGILCPDAAPLLGLVSLMAPAIAMGNRVTLAASEAF 671 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKI-AFTGSTEVGKLVKEA 268 PL A ++ + P GVVNI+ G + ++ H ++ + +G + V EA Sbjct: 672 PLAATDFYQVLDTSDVPAGVVNILTGAHADLAEPMARHLDLDAVWGLSGHAQ----VIEA 727 Query: 269 ASRSNLKR 276 AS NLKR Sbjct: 728 ASAGNLKR 735 >5J77-A nrPDB Length = 508 Score = 306 bits (785), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 169/485 (34%), Positives = 270/485 (55%), Gaps = 13/485 (2%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 TK++I+ +W S SGK +P T + I +E + DVD+A++AA+ AF W L Sbjct: 3 TKLYIDGQWVNSSSGKTVDKYSPVTGQVIGRMEAATRDDVDRAIDAAEDAFW---AWNDL 59 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 ++ R +++++ +L+E++RA L + + GKP A +++G I ++Y+A WA K+ Sbjct: 60 GSVERSKIIYRAKELIEKNRAELENIIMEENGKPVKEAKE-EVDGVIDQIQYYAEWARKL 118 Query: 152 QGKTIP-TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 G+ + T + F P G+ A+TPWNFP M+ KLAPAL GNT+VLKP+ TP Sbjct: 119 NGEVVEGTSSHRKIFQYKVPYGIVVALTPWNFPAGMVARKLAPALLTGNTVVLKPSSDTP 178 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 +A ++ EAG P GV+N + G G +G I H ++N I TGST G+ + + AS Sbjct: 179 GSAEWIVRKFVEAGVPKGVLNFITGRGSEIGDYIVEHKKVNLITMTGSTATGQRIMQKAS 238 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEF 330 +N+ ++ LELGGK P +V DAD+D A++ ++N GQ C AA R++V E +Y F Sbjct: 239 -ANMAKLILELGGKAPFMVWKDADMDNALKTLLWAKYWNAGQSCIAAERLYVHEDIYDTF 297 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME--- 387 + R VE ++K +GDP + + GP I++ E++E K+ GAK+ GGS Sbjct: 298 MSRFVELSRKLALGDPKN--ADMGPLINKGALQATSEIVEEAKESGAKILFGGSQPSLSG 355 Query: 388 --DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 G F PT+ +I +EEIF PV K S+EE+ AN YGL + +FT Sbjct: 356 PYRNGYFFLPTIIGNADQKSKIFQEEIFAPVIGARKISSVEEMYDLANDNKYGLASYLFT 415 Query: 446 KNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 K+ + + + + G +++N +Q GF+M+G E +Y ++EY ++K + + Sbjct: 416 KDPNIIFEASERIRFGELYVNMPGPEASQGYHTGFRMTGQAGEGSKYGISEYLKLKNIYV 475 Query: 506 KLGDK 510 K Sbjct: 476 DYSGK 480 >3I44-A nrPDB Length = 497 Score = 306 bits (784), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 168/475 (35%), Positives = 266/475 (56%), Gaps = 9/475 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K +IN W + + +PST E + G D DKA+ AA+ AFQ W+ Sbjct: 27 KFYINGLWDDPSTPHDLYVIDPSTEEACAVISLGSTRDADKAINAAKKAFQT---WKTTS 83 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R + ++ ++ E+ + +A +M+ G P A +R F + Sbjct: 84 PHERLGFVEKILEIYEKRSSDMAKTISMEMGAPIDMALNAQTATGSSHIRNFIKAYKEFS 143 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 + + N ++ IGV G ITPWN+P+ + K+ PAL G TMVLKP+E PL+ Sbjct: 144 FQEALIEGNEQAILHYDAIGVVGLITPWNWPMNQVTLKVIPALLAGCTMVLKPSEIAPLS 203 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 A+ ++ EA P GV N++ G G VG+ +S+HP + I+FTGST GK + + AS + Sbjct: 204 AMLFAEILDEAALPSGVFNLINGDGANVGSYLSAHPDLEMISFTGSTRAGKDISKNASNT 263 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 LKRV LELGGK I+ ADAD+D A++ + F+N GQ C A +R+ VE+ +Y + ++ Sbjct: 264 -LKRVCLELGGKGANIIFADADID-ALQRGVRHCFYNSGQSCNAPTRMLVEQAIYDKAIK 321 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM---EDK 389 + + A+K VG GP + ++Q+DKI +LI+SG EGA L GG+ + ++ Sbjct: 322 TAKDIAEKTQVGPGHQTGNHIGPVVSKEQYDKIQDLIQSGIDEGATLVTGGTGLPMGMER 381 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 G +++PTVF++V +MRI +EEIFGPV +L F + +E + AN T+YGLT + +++ Sbjct: 382 GYYVRPTVFADVKPHMRIFREEIFGPVLSLLPFNTEDEAVTLANDTEYGLTNYIQSQDRS 441 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 K ++A+ + SG V +N + L + FGG K SG RE G + + E+ + K ++ Sbjct: 442 KCRRIAAQVRSGMVEVNGHE-LPGGSYFGGVKFSGRAREGGLWGIKEFLDTKAIS 495 >3U4J-A nrPDB Length = 528 Score = 306 bits (783), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 186/483 (38%), Positives = 280/483 (57%), Gaps = 6/483 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPS-TREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 ++ ++ + ++ SG +P E + E DV KAV AA+ AF G PW R+ Sbjct: 24 QMLVDGKSVDAASGSTIDRVSPGHAGEVVGTWPEASADDVRKAVAAARKAFDAG-PWPRM 82 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R RL+ ++ADL+ + LA +E+++ GKP A ++ C Y AG A + Sbjct: 83 SGAERSRLMFKVADLILARQEELALIESLEVGKPIAQARG-EIGFCADLWSYAAGQARAL 141 Query: 152 QGKTIPT-DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 +G+T D+ + EP+GV G ITPWNFP ++ ++ A+ G T+VLKP+E T Sbjct: 142 EGQTHNNIGDDRLGLVLREPVGVVGIITPWNFPFIIASERVPWAIGSGCTVVLKPSEFTS 201 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 T++ L L +EAG P GV N+V G+G G ++ P ++ +AFTGS VG + E A+ Sbjct: 202 GTSIRLAELAREAGIPDGVFNVVTGYGDPAGQVLAEDPNVDMVAFTGSVRVGTKLGEIAA 261 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEF 330 R+ +KRV LELGGK P IV ADADLD A + GV+ N GQCC + SR+ V+E + Sbjct: 262 RT-VKRVGLELGGKGPQIVFADADLDAAADGIAYGVYHNAGQCCISGSRLLVQEGIRDAL 320 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM-EDK 389 + R ++ ++K GDP + +T+ G I + +K+ + +G GA+L GG + + Sbjct: 321 MERLLDISRKVAFGDPLNERTKIGAMISEAHAEKVHSYVTAGITSGAELLLGGERIGREA 380 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 GL+ PTVF+ VT +M IA+EEIFGPV L FK+ +E + AN+T++GL+A+V++ NL+ Sbjct: 381 GLYYAPTVFAGVTPDMSIAREEIFGPVLSTLTFKTADEAVALANATEFGLSASVWSTNLE 440 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGD 509 AL+ + +G WIN + P GG+K SG GRELG Y EY++ K V + LG Sbjct: 441 TALQTIRRIRAGRCWINSVIDGTPELPIGGYKKSGLGRELGRYGFDEYSQFKGVHVTLGR 500 Query: 510 KNP 512 P Sbjct: 501 PAP 503 >3TY7-A nrPDB Length = 478 Score = 305 bits (781), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 183/479 (38%), Positives = 260/479 (54%), Gaps = 18/479 (3%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 +TK +IN EW ES S + NP+T E I +V +G+K DVDKAVEAA + +R Sbjct: 7 YTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADDVYLE---FRH 63 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 R LL ++ E + + T + G P + + + L +F D Sbjct: 64 TSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQ---MGLNHFVAARDA 120 Query: 151 IQGKTIPT---DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 + DD VV E IGV G ITPWNFP KLA A G+ +VLKP+E Sbjct: 121 LDNYEFEERRGDDLVV----KEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSE 176 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 +TP A+ L + + G P GV N+V G G VG +S HP++ ++FTGS G + E Sbjct: 177 ETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIME 236 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 A++ + K+V+LELGGK+P IV D D+ A + V N GQ CTA +RV V ++ Sbjct: 237 KAAK-DFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNKIK 295 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 F+ E + VG+P + T+ GP I +KQFD++ I G +EGA+L GG Sbjct: 296 DAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPGKP 355 Query: 388 ---DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 +KG F +PT+F V + M IA+EEIFGPV ++ + ++E I+ AN T YGL V Sbjct: 356 EGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGYVI 415 Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 K+ + K+A ++E+GTV IN PFGG+K SG GRE G+Y + E+ EVK++ Sbjct: 416 GKDKETLHKVARSIEAGTVEINEA-GRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSI 473 >4U3W-A nrPDB Length = 505 Score = 302 bits (774), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 179/488 (36%), Positives = 261/488 (53%), Gaps = 15/488 (3%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 + + +IN E+ SG F +P ++ +V E D VD AV+AA A + G WR Sbjct: 22 QLLRHYINGEF--VASGTTFPNLSPVDGRKLADVCEADAALVDSAVQAAHAAQKAG--WR 77 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R LH++AD +E A E DTG+P A +D+ I R FA Sbjct: 78 DTTPAQRAAWLHKIADGIEARFDEFVAAEVADTGRPVAQARTLDIARGIANFRTFADLVR 137 Query: 150 KIQGKTIPTD----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKP 205 G+ T ++ + +P+GV G I+PWN PLL+ WK+APAL GN +V KP Sbjct: 138 TASGEYFETHAADGSELINYVTRKPLGVIGIISPWNLPLLLFTWKVAPALAMGNCVVAKP 197 Query: 206 AEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV-GAAISSHPQINKIAFTGSTEVGKL 264 +E+TP +A L ++ + G PPGV N++ G G G ++ HP I+ I FTG + G Sbjct: 198 SEETPSSATLLAEVMHDVGLPPGVFNLIHGHGQNAAGEFLTRHPDISAITFTGESRTGST 257 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + +A + +K V+ ELGGKN +V ADAD D AV + F N GQ C + RV+VE Sbjct: 258 IMKAVA-DGVKEVSFELGGKNAAVVFADADFDAAVAGVLRSSFTNAGQVCLCSERVYVER 316 Query: 325 QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS 384 ++ FV E A+ VG P D T GP I + DK+L +EGA + GG Sbjct: 317 PIFERFVAALKEQAQALRVGAPEDPATTMGPLISRGHRDKVLSYFRLAVEEGATVVTGGG 376 Query: 385 A-----MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 A D G F+ PT+++ + D+ R +EEIFGPV I F EV+KR N + YGL Sbjct: 377 APSFGDARDDGAFVMPTIWTGLPDSARCVREEIFGPVCHIAPFDDEAEVVKRVNDSAYGL 436 Query: 440 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTE 499 A+++T L + ++A +E+G VW+N + + PFGG K+SG GRE G ++L Y+E Sbjct: 437 AASIWTTQLARGHRVAKQIETGIVWVNAWFVRDLRTPFGGTKLSGLGREGGRHSLDFYSE 496 Query: 500 VKTVTIKL 507 + V +++ Sbjct: 497 LTNVCVRI 504 >4YWE-A nrPDB Length = 487 Score = 301 bits (771), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 183/481 (38%), Positives = 259/481 (53%), Gaps = 9/481 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 K FI EW + +PS + + G PD+++AV AA+ AF PW Sbjct: 12 AKHFIAGEWTLPAQLETIPVVDPSDGQPFATIARGTAPDIERAVAAARDAFA--GPWGAA 69 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 A RGR+L +L+ V LAA+E DTGKP L D R ++AG ADK+ Sbjct: 70 SAAERGRVLMRLSARVTDSIEELAAIEARDTGKP-LKQARADAAALARYFEFYAGAADKL 128 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G+T+P T EP GV G I PWN+P+ + + AL GN V+KPAE L Sbjct: 129 HGETLPYQAGYTVLTVREPHGVTGHIVPWNYPMQIFGRSVGAALAAGNACVVKPAEDACL 188 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L + L EAG P G +NIV G+G GAA++ HP I+ I+FTGS GKLV + A+ Sbjct: 189 SVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGIDHISFTGSPATGKLVTQMAAE 248 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 +++ VTLELGGK+P IV ADADLD A+ + N GQ C+A SRV +E VY V Sbjct: 249 NHVP-VTLELGGKSPQIVFADADLDAALPVLVSAIVQNGGQTCSAGSRVLIERAVYEPLV 307 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED--- 388 R VG P + GP I+ KQ ++ + + + +G + G + D Sbjct: 308 ERLATAFNGLRVG-PSRADLDCGPLINAKQQQRVWDFLSDAQHDGIPMAAHGQVVADAPE 366 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 G + P + +V + R+A+EE+FGPV ++F +E + AN T YGL A ++T++ Sbjct: 367 SGFYQAPALLRDVPPSHRLAQEEVFGPVLAAMRFVDEDEAVALANGTPYGLVAGIWTRDG 426 Query: 449 DKALKLASALESGTVWINCYNALYA-QAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 + ++LA L +G V+IN Y A + PFGG SG+GRE G AL +T +KT+ I+ Sbjct: 427 ARQMRLARRLRAGQVFINNYGAGGGVELPFGGVGHSGHGREKGFEALYGFTALKTIAIRH 486 Query: 508 G 508 G Sbjct: 487 G 487 >5EUY-A nrPDB Length = 491 Score = 296 bits (757), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 167/478 (34%), Positives = 263/478 (55%), Gaps = 15/478 (3%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 +IN E+ E +G +P +I EV + D +A+++A F+ W + A+ Sbjct: 12 YINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSA---FEALKAWANIPAI 68 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 R L+++ ++ + + + T++ G + + ++ R ++ A A QG+ Sbjct: 69 RRAEYLYKMLEVFRQMKEDFMKILTVEGGGTY-RKVWGEVVFTERLIQNAAELARHYQGR 127 Query: 155 TIPTDDNV---VCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 + +D V F R + GV G ITPWN+PL + + K+A L GNT+V KPA TP+ Sbjct: 128 VLQSDSESTISVVFKRSK--GVVGVITPWNYPLSISMKKIAHTLAVGNTVVYKPASDTPV 185 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 T + ++ +AG P GV N+V G GP VG I +H ++ + FTG + G+ + A+ Sbjct: 186 TGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGREIAAKAA- 244 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 LK VTLELGG +P I+ D D+D A A F+QGQ CT+A R+ V + V +F+ Sbjct: 245 GTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHKAVADKFI 304 Query: 332 RRSVEYAKKRPVGDPF-DVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKG 390 R V Y K + DP D K + GP I+++Q + E ++ G +L GG + G Sbjct: 305 ERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGGRSW---G 361 Query: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450 F +P +F +V N RI +EE+FGPV+PI+ ++ ++ ++ AN TDYGL+ AV T N+++ Sbjct: 362 NFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAVLTNNVNR 421 Query: 451 ALKLASALESGTVWINCYNAL-YAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 A ++A A+ESG IN L + PFGG K SG GRE GE++ E T + VT+ L Sbjct: 422 AFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRWVTVTL 479 >1WNB-A nrPDB Length = 495 Score = 293 bits (749), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 166/476 (34%), Positives = 262/476 (55%), Gaps = 8/476 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K+ IN E S G+K NP+T + + E+ E ++ A + A + W + Sbjct: 25 KLLINGEL-VSGEGEKQPVYNPATGDVLLEIAEAS---AEQVDAAVRAADAAFAEWGQTT 80 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R L +LAD++E + A LE+ + GKP AF ++ + R+FAG A + Sbjct: 81 PKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLN 140 Query: 153 GKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G + R +P+GV +I PWN+PL+M WKLAPAL GN +VLKP+E TPL Sbjct: 141 GLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPL 200 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 TAL L L K+ FP GVVNI+ G G TVG ++ HP++ ++ TGS G+ + + + Sbjct: 201 TALKLAELAKDI-FPAGVVNILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHII-SHTA 258 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 S++KR +ELGGK P IV DAD++ VE ++N GQ CTAA R++ ++ +Y V Sbjct: 259 SSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLV 318 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA-KLECGGSAMEDKG 390 + G P D TE GP +++ + +E K G K+ GG + G Sbjct: 319 EKLGAAVATLKSGAPDDESTELGPLSSLAHLERVGKAVEEAKATGHIKVITGGEKRKGNG 378 Query: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450 + PT+ + + I ++E+FGPV + F + E+V+ AN + YGL ++V+TK++ + Sbjct: 379 YYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKDVGR 438 Query: 451 ALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 A ++++ L+ G W+N + L ++ P GG K+SG G+++ Y L +YT V+ V +K Sbjct: 439 AHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVK 494 >4V6H-A nrPDB Length = 484 Score = 292 bits (748), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 177/488 (36%), Positives = 259/488 (53%), Gaps = 6/488 (1%) Query: 21 PRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQV 80 P +++ + + +I EW + S F +P+T E + V K + A + Sbjct: 2 PGSMKDPSLLRHQAYIGGEWQAADSDATFEVFDPATGESLGTVP---KMGAAETARAIEA 58 Query: 81 AFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT 140 A + WR A R +L + DLV + LA + T + GKP A ++ Sbjct: 59 AQAAWAGWRMKTAKERAAILRRWFDLVIANSDDLALILTTEQGKPLAEAKG-EIAYAASF 117 Query: 141 LRYFAGWADKIQGKTIPT-DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGN 199 + +FA ++ G T+PT D N EPIGVC AITPWNFP M+ K+ PAL G Sbjct: 118 IEWFAEEGKRVAGDTLPTPDANKRIVVVKEPIGVCAAITPWNFPAAMIARKVGPALAAGC 177 Query: 200 TMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 +V+KPAE TP +AL + L + AG P GV+++V G +G I+S+P + K++FTGST Sbjct: 178 PIVVKPAESTPFSALAMAFLAERAGVPKGVLSVVIGDPKAIGTEITSNPIVRKLSFTGST 237 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319 VG+L+ A S +K++TLELGG P IV DADLD AVE A + N GQ C +R Sbjct: 238 AVGRLLM-AQSAPTVKKLTLELGGNAPFIVFDDADLDAAVEGAIASKYRNNGQTCVCTNR 296 Query: 320 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL 379 FV E+VY F + K VG + GP I++ K+ I +GA L Sbjct: 297 FFVHERVYDAFADKLAAAVSKLKVGRGTESGATLGPLINEAAVKKVESHIADALAKGASL 356 Query: 380 ECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 GG F +PTV + V +M +AKEE FGP+ P+ +F S EE+++ AN T++GL Sbjct: 357 MTGGKRHALGHGFFEPTVLTGVKPDMDVAKEETFGPLAPLFRFASEEELVRLANDTEFGL 416 Query: 440 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTE 499 A ++++++ + ++A ALE G V IN APFGG K SG GRE Y + +Y Sbjct: 417 AAYLYSRDIGRVWRVAEALEYGMVGINTGLISNEVAPFGGVKQSGLGREGSHYGIDDYVV 476 Query: 500 VKTVTIKL 507 +K + + + Sbjct: 477 IKYLCVAV 484 >3EK1-A nrPDB Length = 504 Score = 289 bits (740), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 182/473 (38%), Positives = 261/473 (55%), Gaps = 8/473 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 ++ +N W ++ G NP+ I V + +A++A+ A S W Sbjct: 33 SQCLVNGRWIDAADGTTIKVTNPADGSVIGTVPSLSVATIKEAIDASAKAL---SGWAAK 89 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 A R +L + DL+ + +A + T + GKP A L + +FA A ++ Sbjct: 90 TAKERAGILRKWFDLIIANADDIALIMTSEQGKPLAEARGEVLYAA-SFIEWFAEEAKRV 148 Query: 152 QGKTIPTDDNVVCFTR-HEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 G TIP N T +P+GV AITPWNFP M+ K APAL G TM+++PA+ TP Sbjct: 149 YGDTIPAPQNGQRLTVIRQPVGVTAAITPWNFPAAMITRKAAPALAAGCTMIVRPADLTP 208 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 LTAL LG L ++AG P GV+ IV G +GA ++S+ + K++FTGSTEVG+L+ A Sbjct: 209 LTALALGVLAEKAGIPAGVLQIVTGKAREIGAELTSNDTVRKLSFTGSTEVGRLLM-AQC 267 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEF 330 +KR++LELGG P IV DADLD AV+ A + N GQ C A+R++V+ VY +F Sbjct: 268 APTIKRISLELGGNAPFIVFDDADLDAAVDGAMVSKYRNAGQTCVCANRIYVQRGVYDKF 327 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKG 390 + K+ VG+ + GP I++K K+ IE +GAKL GG E G Sbjct: 328 AEKLAAKVKELKVGNGTEPGVVIGPMIEEKAITKVKAHIEDAVSKGAKLITGGK--ELGG 385 Query: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450 LF +P + + VT +M +AKEE FGP+ P+ F + EEVI +AN T +GL A +T+N + Sbjct: 386 LFFEPGILTGVTSDMLVAKEETFGPLAPLFAFDTEEEVIAQANDTIFGLAAYFYTENFSR 445 Query: 451 ALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 A++++ ALE G V N APFGG K SG GRE +Y + EY E K + Sbjct: 446 AIRVSEALEYGMVGHNTGLISNEVAPFGGVKQSGLGREGSKYGIEEYLETKYI 498 >2HG2-A nrPDB Length = 479 Score = 289 bits (739), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 160/478 (33%), Positives = 263/478 (55%), Gaps = 13/478 (2%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP-WRRLD 92 ++I+ ++ + NP+T I + +G D KA++AA+ R P W L Sbjct: 9 MYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAE----RAQPEWEALP 64 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 A+ R L +++ + R+RA+ + ++ G +++ + Y A WA + + Sbjct: 65 AIERASWLRKISAGI-RERASEISALIVEEGGKIQQLAEVEVAFTADYIDYMAEWARRYE 123 Query: 153 GKTIPTD---DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 G+ I +D +N++ F R +GV I PWNFP ++ K+APAL GNT+V+KP+E T Sbjct: 124 GEIIQSDRPGENILLFKR--ALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFT 181 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 P A+ ++ E G P GV N+V G G TVG ++ +P++ ++ TGS G+ + A Sbjct: 182 PNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMATA 241 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 ++ N+ +V LELGGK P IV DADL+LAV+ N GQ C A RV+V++ +Y + Sbjct: 242 AK-NITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQ 300 Query: 330 FVRRSVEYAKKRPVGDPFDVK-TEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED 388 FV R E + G+P + GP I+ +++ + + +EGA++ GG A+E Sbjct: 301 FVNRLGEAMQAVQFGNPAERNDIAMGPLINAAALERVEQKVARAVEEGARVAFGGKAVEG 360 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 KG + PT+ +V M I EE FGPV P++ F ++E+ I AN +DYGLT++++T+NL Sbjct: 361 KGYYYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDAISMANDSDYGLTSSIYTQNL 420 Query: 449 DKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 + A+K L+ G +IN N Q G++ SG G G++ L EY + + V ++ Sbjct: 421 NVAMKAIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLHEYLQTQVVYLQ 478 >3B4W-A nrPDB Length = 495 Score = 289 bits (739), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 180/481 (37%), Positives = 256/481 (53%), Gaps = 6/481 (1%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 ++ K+FI +W + + P+T E + +V DVD AV AA+ AF G PW Sbjct: 7 EYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAADVDAAVAAARAAFDNG-PWP 65 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R ++ ++ + L +TG+P + G + + YFAG AD Sbjct: 66 STPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPPTIIETMHWMGSMGAMNYFAGAAD 125 Query: 150 KIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 K+ T EP+GV GAI WN PL + V K+APAL G T+VLKPA +T Sbjct: 126 KVTWTETRTGSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVLKPAAET 185 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 PLTA L + E G P GV+++VPG G G A++S+P I+ FTGS+ VG+ V A Sbjct: 186 PLTANALAEVFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGREVGRRA 244 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 + LK TLELGGK+ I+ D DL A+ N GQ C +R+ Y E Sbjct: 245 AEM-LKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQTRILAPRSRYDE 303 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME-- 387 V + PVG P D + GP I +KQ ++ I G +EGA+L CGG E Sbjct: 304 IVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGYIAKGIEEGARLVCGGGRPEGL 363 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 D G FI+PTVF++V + M IA+EEIFGPV I+ + + E+ I AN + YGL +V+T + Sbjct: 364 DNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAGSVWTTD 423 Query: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 + K +K++ + +GT IN Y A +PFGG+K SG GRE G + +T+ K+V + + Sbjct: 424 VPKGIKISQQIRTGTYGINWY-AFDPGSPFGGYKNSGIGRENGPEGVEHFTQQKSVLLPM 482 Query: 508 G 508 G Sbjct: 483 G 483 >3RJL-A nrPDB Length = 538 Score = 288 bits (738), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 173/491 (35%), Positives = 262/491 (53%), Gaps = 28/491 (5%) Query: 36 INNEW-----------HESKSGKKFATCNPSTREQIC-EVEEGDKPDVDKAVEAAQVAFQ 83 +NNEW ++ K + NP+ +E++ V + + +KA++AA AF+ Sbjct: 29 VNNEWLGQSYPLVIDGERYETENKIVSINPANKEEVVGTVSKATQDHAEKAIQAAAKAFE 88 Query: 84 RGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 WR D R +L + V R + +AL + GKP+ A D I + Y Sbjct: 89 T---WRYTDPEERAAVLFRAVAKVRRKKHEFSALLVKEAGKPWNEAD-ADTAEAIDFMEY 144 Query: 144 FAGWADKI-QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMV 202 +A ++ +GK + + + + P GV I PWNF ++ + GNT+V Sbjct: 145 YARQMIELAKGKPVNSREGERNQYVYTPTGVTVVIPPWNFLFAIMAGTTVAPIVTGNTVV 204 Query: 203 LKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG 262 LKPA P+ A +++E+G P GVVN VPG G VG + HP+ + I FTGS EVG Sbjct: 205 LKPASAAPVIAAKFVEVLEESGLPKGVVNFVPGSGAEVGDYLVDHPKTSIITFTGSREVG 264 Query: 263 KLVKEAASR-----SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAA 317 + E A++ ++LK+V E+GGK+ +V D D++LA + F GQ C+A Sbjct: 265 TRIFERAAKVQPGQTHLKQVIAEMGGKDTVVVDEDCDIELAAQSIFTSAFGFAGQKCSAG 324 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 SR V E+VY E ++R +E + + VG+P GP IDQ F+KI++ IE GK+EG Sbjct: 325 SRAVVHEKVYDEVLKRVIEITESKKVGEPDSADVYMGPVIDQASFNKIMDYIEIGKEEG- 383 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 +L GG + KG FI+PT+F+++ R+ +EEIFGPV K S +E ++ AN+T+Y Sbjct: 384 RLVSGGKGDDSKGYFIEPTIFADLDPKARLMQEEIFGPVVAFSKVSSFDEALEVANNTEY 443 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWI--NCYNALYAQAPFGGFKMSGNGRELG--EYA 493 GLT AV TKN D + G ++ NC A+ PFGGFKMSG + G +Y Sbjct: 444 GLTGAVITKNRDHINRAKQEFHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDY- 502 Query: 494 LAEYTEVKTVT 504 LA + + KT++ Sbjct: 503 LALHMQAKTIS 513 >4JZ6-A nrPDB Length = 500 Score = 288 bits (738), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 175/481 (36%), Positives = 266/481 (55%), Gaps = 14/481 (2%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 TK+FINN W +S + F +P + E + E D KA +AA+ AF+ W+ + Sbjct: 20 TKLFINNAWIDSSDQQTFERKHPVSSEVMTESANATVTDAIKAAQAAEEAFK---TWKDV 76 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R RLL ++AD++E + M+ G L A F ++ R A A +I Sbjct: 77 GPSERRRLLLKVADVMESKTPKFIEVMAMEVGASALWAGF-NVHASANVFREAASLATQI 135 Query: 152 QGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 QG+TIPTD + T +P+G +I PWN ++ +A L CGNT+V K +E +P Sbjct: 136 QGETIPTDKAETLSMTLRQPVGPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSEFSP 195 Query: 211 LTALYLGSLIKEAGFPPGVVNIV---PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 T + ++EAG P GV+N + P P + A+ S +I +I FTGST VG ++ + Sbjct: 196 ATHALITQCVQEAGLPAGVLNYLNSSPDRSPEIADALISAKEIRRINFTGSTRVGSIIAQ 255 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 A++ +LKR LELGGK+P IV DAD++ AV+ A G F QGQ C + R+ V+E++ Sbjct: 256 KAAQ-HLKRCLLELGGKSPLIVLDDADINAAVKAAVFGSFLFQGQICMSTERLVVDEKIA 314 Query: 328 SEFVRRSVEYAKKRPVGDP-FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM 386 EFV R VE ++ VGDP GP + ++I L + +GAK+ CGG A Sbjct: 315 DEFVARFVEKTERLSVGDPCLTGDCIIGPMVSPNSGERINGLFKDAIDKGAKVVCGGMA- 373 Query: 387 EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 +G + T+ V +MRI EE FGP+ +++ K E I+ AN + YGL++ VF + Sbjct: 374 --QGAVMPATILDHVKSDMRIYDEETFGPITVVIRCKGEAEAIRIANDSVYGLSSGVFGR 431 Query: 447 NLDKALKLASALESGTVWINCYNALY-AQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 ++++AL++ ++E G V IN AQAP+GG K +G GR G + E+TE+K +TI Sbjct: 432 DINRALRVGMSIEYGCVHINGSTVQNEAQAPYGGTKNTGYGRFDGRAVIDEFTELKWLTI 491 Query: 506 K 506 + Sbjct: 492 E 492 >6C43-A nrPDB Length = 477 Score = 286 bits (732), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 168/464 (36%), Positives = 256/464 (55%), Gaps = 9/464 (1%) Query: 46 GKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLAD 105 G++ + NP+T E I E+ E VD AV+AA AF + W + +R L +LAD Sbjct: 19 GERQSVYNPATGEVILEIAEASPAQVDAAVQAADNAF---AEWGQTTPKARAECLLKLAD 75 Query: 106 LVERDRATLAALETMDTGKPFLHAFFID-LEGCIRTLRYFAGWADKIQGKTIPTD-DNVV 163 +E++ A LE+ + GKP LH D + + R+FAG A + G + Sbjct: 76 SIEQNALEFARLESQNCGKP-LHCVINDEIPAIVDVFRFFAGAARCLSGLAAGEYLEGHT 134 Query: 164 CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA 223 R +PIGV +I PWN+PL+M WKLAPAL GN +V+KP+E TPLTAL L L K+ Sbjct: 135 SMIRRDPIGVVASIAPWNYPLMMAAWKLAPALAAGNCVVIKPSEITPLTALKLAVLAKDI 194 Query: 224 GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGG 283 FPPGV+N++ G G TVG ++ H ++ ++ TGS G+ + + + +KR +ELGG Sbjct: 195 -FPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGEHILRHTAPA-IKRTHMELGG 252 Query: 284 KNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPV 343 K P IV DADLD + F+N GQ CTAA R++ + +Y V + + Sbjct: 253 KAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAACRIYAQRGIYDALVEKLGNAVSSLKM 312 Query: 344 GDPFDVKTEQGPQIDQKQFDKILELIESGKK-EGAKLECGGSAMEDKGLFIKPTVFSEVT 402 G P D TE GP ++ +E K ++ GGS E KG + PT+ ++ Sbjct: 313 GAPEDESTELGPLSSLAHLKRVTAAVEEAKALSHIRVITGGSQTEGKGYYFAPTLLADAK 372 Query: 403 DNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGT 462 I + E+FGPV I F ++V++ AN + YGL ++V+T+++ +A +L++ L+ G Sbjct: 373 QEDAIVQREVFGPVVSITVFDDEDQVLRWANDSRYGLASSVWTQDVGRAHRLSARLQYGC 432 Query: 463 VWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 WIN + L ++ P GG K SG G+++ Y L +YT V+ + +K Sbjct: 433 TWINTHFMLVSEMPHGGQKQSGYGKDMSLYGLEDYTLVRHIMVK 476 >3RHD-A nrPDB Length = 486 Score = 285 bits (729), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 173/478 (36%), Positives = 269/478 (56%), Gaps = 23/478 (4%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 +FI+ +W + NP + E I ++ + + +A++ A+ + + L Sbjct: 2 MFIDGKWINRED---MDVINPYSLEVIKKIPALSREEAKEAIDTAE---KYKEVMKNLPI 55 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 R +L +A ++ + LA + +D GKP A +++E I T + A + + + Sbjct: 56 TKRYNILMNIAKQIKEKKEELAKILAIDAGKPIKQAR-VEVERSIGTFKLAAFYVKEHRD 114 Query: 154 KTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213 + IP+DD ++ FTR EP+G+ GAITP+NFPL + K+APA+ GN +V P+ + PL Sbjct: 115 EVIPSDDRLI-FTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVC 173 Query: 214 LYLGSLIKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 + L +I+ A P GV N++ G G VG I + ++N I+FTGS++VG+L+ Sbjct: 174 IELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELI---T 230 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 ++ K++ LELGG NP IV DADL+ AV +G F GQ C + + V+E + + Sbjct: 231 KKAGFKKIALELGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADK 290 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK 389 F+ V AK VG+P D KT+ GP I + + + +++E EG KL GG DK Sbjct: 291 FIEMFVNKAKVLNVGNPLDEKTDVGPLISVEHAEWVEKVVEKAIDEGGKLLLGGK--RDK 348 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 LF PT+ DN+ + K E F PV PI++ EE+I ANST+YGL +A+FT +++ Sbjct: 349 ALFY-PTILEVDRDNI-LCKTETFAPVIPIIRTNE-EEMIDIANSTEYGLHSAIFTNDIN 405 Query: 450 KALKLASALESGTVWINCYNALYAQ--APFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 K+LK A LE G V IN ++L+ Q PFGG K SG GRE +YA+ E + +KT+ I Sbjct: 406 KSLKFAENLEFGGVVIND-SSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIII 462 >3QAN-A nrPDB Length = 538 Score = 285 bits (729), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 174/471 (36%), Positives = 259/471 (54%), Gaps = 23/471 (4%) Query: 48 KFATCNPSTREQIC-EVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADL 106 K + NP+ ++Q+ V + ++ +KA+++A AFQ WR ++ R +L + A + Sbjct: 52 KIQSWNPARKDQLVGSVSKANQDLAEKAIQSADEAFQ---TWRNVNPEERANILVKAAAI 108 Query: 107 VERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI-QGKTI---PTDDNV 162 + R + +A + GKP+ A D I L Y+A ++ +GK I P + N Sbjct: 109 IRRRKHEFSAWLVHEAGKPWKEAD-ADTAEAIDFLEYYARQMIELNRGKEILSRPGEQNR 167 Query: 163 VCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKE 222 +T P+GV I+PWNF L ++V + GNT+VLKPA TP+ A ++++ Sbjct: 168 YFYT---PMGVTVTISPWNFALAIMVGTAVAPIVTGNTVVLKPASTTPVVAAKFVEVLED 224 Query: 223 AGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS-----RSNLKRV 277 AG P GV+N VPG G VG + HP+ + I FTGS +VG + E A+ +++LKRV Sbjct: 225 AGLPKGVINYVPGSGAEVGDYLVDHPKTSLITFTGSKDVGVRLYERAAVVRPGQNHLKRV 284 Query: 278 TLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEY 337 +E+GGK+ +V DADLDLA E F GQ C+A SR + + VY E + ++V Sbjct: 285 IVEMGGKDTVVVDRDADLDLAAESILVSAFGFSGQKCSAGSRAVIHKDVYDEVLEKTVAL 344 Query: 338 AKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTV 397 AK VGDP + GP ID+K F+KI+ IE GKKEG +L GG G FI+PT+ Sbjct: 345 AKNLTVGDPTNRDNYMGPVIDEKAFEKIMSYIEIGKKEG-RLMTGGEGDSSTGFFIQPTI 403 Query: 398 FSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASA 457 +++ I +EEIFGPV K + ++ AN+T+YGLT AV T+N + Sbjct: 404 IADLDPEAVIMQEEIFGPVVAFSKANDFDHALEIANNTEYGLTGAVITRNRAHIEQAKRE 463 Query: 458 LESGTVWI--NCYNALYAQAPFGGFKMSGNGRELG--EYALAEYTEVKTVT 504 G ++ NC A+ PFGGFKMSG + G +Y LA + + KTV+ Sbjct: 464 FHVGNLYFNRNCTGAIVGYHPFGGFKMSGTDSKAGGPDY-LALHMQAKTVS 513 >6FK3-A nrPDB Length = 536 Score = 276 bits (707), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 185/474 (39%), Positives = 251/474 (52%), Gaps = 31/474 (6%) Query: 53 NPSTREQI-CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDR 111 NPS RE + E DK V KA A+ AF + W R A RG++L L ++ER++ Sbjct: 39 NPSDREDVVARFPEADKDLVRKAALKAREAF---AEWSRTPAPIRGQVLFNLVKILEREK 95 Query: 112 ATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTD-DNVVCFTRHEP 170 TL L + GK A D++ I T +FA ++ G+T+P++ + FT P Sbjct: 96 PTLTRLMVREVGKTPKEAAG-DVQEAIDTALFFASEGRRLYGQTVPSEMRDKELFTFRRP 154 Query: 171 IGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVV 230 +GV G IT NFP+ + WKL PA+ GNT+V KP+E P + L +EAG PPGV+ Sbjct: 155 LGVVGIITAGNFPIAVPSWKLIPAVLTGNTVVWKPSEDAPTLSFVFAKLFEEAGLPPGVL 214 Query: 231 NIVPGFGPTVGAA------ISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284 N+V FG G+ + K AFTGST+VG+ + E A R NL R TLELGGK Sbjct: 215 NVV--FGGGKGSTGQWMVELMDEGLFQKFAFTGSTQVGRWIGEVAGR-NLIRPTLELGGK 271 Query: 285 NPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVG 344 NP +V DADLDLAVE A F GQ CT+A + V+ +Y EF RR +E + VG Sbjct: 272 NPLVVMRDADLDLAVEGAWWSAFATGGQRCTSAGNILVDAPIYEEFKRRFLERVEATLVG 331 Query: 345 DP-FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME------------DKGL 391 +P + GP I+++ F + E G+ EGA+L G + + GL Sbjct: 332 NPLLHPEVTYGPFINERFFARWQEHYRVGEAEGARLLFGRGRITRENPYPRFLGDPEAGL 391 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 + PTV+ EV R+ EE+FGP ++K IEE I ANST YGL++A++T + A Sbjct: 392 YGWPTVW-EVRPGTRLFTEEVFGPTINLVKVDGIEEAIAVANSTPYGLSSAIYTNHRHWA 450 Query: 452 LKLASALESGTVWINCYN-ALYAQAPFGGFKMSGN-GRELGEYALAEYTEVKTV 503 + +G IN A PFGG K SGN GRE G + L EYT V Sbjct: 451 YLFKVGIRAGMTSINNATVGAEAHLPFGGVKASGNGGRESGIWVLEEYTYWHAV 504 >3K2W-A nrPDB Length = 497 Score = 273 bits (698), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 173/488 (35%), Positives = 253/488 (51%), Gaps = 10/488 (2%) Query: 24 IRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQ 83 +++L K FI ++ S +PST + I E+ G K D + A+E VA Sbjct: 5 VQDLHFKNKVNFIGGQYVPSNESDTIDILSPSTGKVIGEIPAGCKADAENALE---VAQA 61 Query: 84 RGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 W +L A +R +L A+ + ++ LA + + GK L ++++ + Y Sbjct: 62 AQKAWAKLTARTRQNMLRTFANKIRENKHILAPMLVAEQGK-LLSVAEMEVDVTATFIDY 120 Query: 144 FAGWADKIQGKTIPTDDNVVCFTRHE-PIGVCGAITPWNFPLLMLVWKLAPALCCGNTMV 202 A I+G +P+D+ H+ P GV IT WNFPL + K+ PAL GNTMV Sbjct: 121 GCDNALTIEGDILPSDNQDEKIYIHKVPRGVVVGITAWNFPLALAGRKIGPALITGNTMV 180 Query: 203 LKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG 262 LKP ++TPL LG + KEAG P GV+N++ G G VG + P I TGST G Sbjct: 181 LKPTQETPLATTELGRIAKEAGLPDGVLNVINGTGSVVGQTLCESPITKMITMTGSTVAG 240 Query: 263 KLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFV 322 K + + ++ + V LELGGK P +V DADLD A E A G F N GQ CT R++V Sbjct: 241 KQIYKTSAEY-MTPVMLELGGKAPMVVMDDADLDKAAEDALWGRFANCGQVCTCVERLYV 299 Query: 323 EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECG 382 VY EF+ + + K VGDP D ++ GP+ +Q++ D I ++ K+GA + G Sbjct: 300 HASVYDEFMAKFLPLVKGLKVGDPMDADSQMGPKCNQREIDNIDHIVHEAIKQGATVATG 359 Query: 383 GSAME----DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG 438 G + G + +PTV +V + + EE FGP+ PI+K S+E+ I+ N + YG Sbjct: 360 GKTATVEGFEGGCWYEPTVLVDVKQDNIVVHEETFGPILPIVKVSSMEQAIEFCNDSIYG 419 Query: 439 LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYT 498 L+A V T++ + S LE G V+IN Q G+K SG G E G++ L +Y Sbjct: 420 LSAYVHTQSFANINQAISDLEVGEVYINRGMGEQHQGFHNGWKQSGFGGEDGKFGLEQYL 479 Query: 499 EVKTVTIK 506 E KTV I Sbjct: 480 EKKTVYIN 487 >5UR2-A nrPDB Length = 984 Score = 271 bits (694), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 180/485 (37%), Positives = 271/485 (55%), Gaps = 26/485 (5%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQIC-EVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 I INN+ E +SGK F NPS +QI +++ ++A++AAQ A++ W+ + Sbjct: 499 IVINNK--ELQSGKIFDRVNPSQSDQIVGKIQMATTEQAEQAMQAAQTAYKT---WKNVP 553 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R L+ +LAD++ RDR L A + ++ GKP+ A D+ I RY+A ++Q Sbjct: 554 CEQRAALVDKLADIMTRDRFKLIATQVLEVGKPWAEADG-DIGEAIDFCRYYARHMRELQ 612 Query: 153 GKT----IPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQ 208 +P + + + GV I PWNFPL +L + A GNT+V+KPAEQ Sbjct: 613 KPLRVGGLPGELSHYIYKSR---GVTAVIAPWNFPLAILAGMVTAAAVAGNTVVMKPAEQ 669 Query: 209 TPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEA 268 + + A L +I+EAGFP GV+N +PG+G VG I +H IAFTGS VG + Sbjct: 670 STVVAWGLMKMIQEAGFPQGVINFLPGYGEEVGEYIVNHKYTTTIAFTGSKAVGLHIMNR 729 Query: 269 AS-----RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 A+ + ++KR +E+GGKN I+ DADLD AV+ F GQ C+AASRV V Sbjct: 730 AAVVQPGQQHVKRCIIEMGGKNAVIIDNDADLDEAVDGVIYSAFGFSGQKCSAASRVIVL 789 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 ++VY FV R VE AK + + K GP +D++ +D+IL I +K KL G Sbjct: 790 DEVYDRFVDRLVETAKSIEIHPAENPKAYMGPVVDKEAYDRILGTIAEAEK-NHKLLFKG 848 Query: 384 SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 S + G F PT+F +V + ++A+ EIFGPV +++ K++++ + ANST+Y LT V Sbjct: 849 S-VPGGGFFAPPTIFGDVPGDAKLAQAEIFGPVVAVIRAKNLDQALDIANSTEYALTGGV 907 Query: 444 FTKNLDKALKLASALESGTVWIN--CYNALYAQAPFGGFKMSGNGRELG--EYALAEYTE 499 F+++ ++ LE G +++N A+ + PFGGFKMSG G + G +Y L +Y E Sbjct: 908 FSRSPANINRVKEELEVGNLYVNRGITGAMVDRHPFGGFKMSGIGSKTGGPDY-LKQYME 966 Query: 500 VKTVT 504 VT Sbjct: 967 PACVT 971 >3R64-A nrPDB Length = 508 Score = 262 bits (669), Expect = 3e-70, Method: Compositional matrix adjust. Identities = 180/491 (36%), Positives = 262/491 (53%), Gaps = 19/491 (3%) Query: 29 VKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPW 88 + TK I +W E S + NP I E ++ DVD A EAA+ A + W Sbjct: 10 IDATKHLIGGQWVEGNSDRISTNINPYDDSVIAESKQASIADVDAAYEAAKKA---QAEW 66 Query: 89 RRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFF-IDLEGCIRTLRYFAGW 147 A R ++++ A+L+E R + ++G A I L G I + A + Sbjct: 67 AATPAAERSAIIYRAAELLEEHREEIVEWLIKESGSTRSKANLEITLAGNIT--KESASF 124 Query: 148 ADKIQGKTIPTD----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 ++ G+ P++ +N V GV G I+PWNFPL + + +APAL GN +V+ Sbjct: 125 PGRVHGRISPSNTPGKENRVYRVAK---GVVGVISPWNFPLNLSIRSVAPALAVGNAVVI 181 Query: 204 KPAEQTPLTALYL-GSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG 262 KPA TP+T + + +EAG P GV++ V G G +G +H I+FTGST VG Sbjct: 182 KPASDTPVTGGVIPARIFEEAGVPAGVISTVAGAGSEIGDHFVTHAVPKLISFTGSTPVG 241 Query: 263 KLVKEAASRSN-LKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVF 321 + V E A +K V LELGG P +V ADAD+D A + A G F +QGQ C + +RV Sbjct: 242 RRVGELAINGGPMKTVALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVI 301 Query: 322 VEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLEC 381 V+ V+ EF+ + VE K P GDP T GP I+ Q + E IE KKEGA ++ Sbjct: 302 VDAAVHDEFLEKFVEAVKNIPTGDPSAEGTLVGPVINDSQLSGLKEKIELAKKEGATVQV 361 Query: 382 GGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTA 441 G +G + P VFS+VT +M IA+EEIFGP+ +LK + AN++D+GL+A Sbjct: 362 EGPI---EGRLVHPHVFSDVTSDMEIAREEIFGPLISVLKADDEAHAAELANASDFGLSA 418 Query: 442 AVFTKNLDKALKLASALESGTVWINCYNAL-YAQAPFGGFKMSGNGRELGEYALAEYTEV 500 AV++K++D+A + A ++SG V IN FGG K SG GR G++A+ E+T Sbjct: 419 AVWSKDIDRAAQFALQIDSGMVHINDLTVNDEPHVMFGGSKNSGLGRFNGDWAIEEFTTD 478 Query: 501 KTVTIKLGDKN 511 + + IK +N Sbjct: 479 RWIGIKRSAEN 489 >5X5U-A nrPDB Length = 505 Score = 261 bits (668), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 164/481 (34%), Positives = 245/481 (50%), Gaps = 6/481 (1%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRG 85 N+ T++ I+ EW ++ SGK NP+T + I V D+D+A+ AAQ F+ Sbjct: 27 NVTYTDTQLLIDGEWVDAASGKTIDVVNPATGKPIGRVAHAGIADLDRALAAAQSGFEA- 85 Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 WR++ A R + + A LV +A L T + GKP A +++ + +FA Sbjct: 86 --WRKVPAHERAATMRKAAALVRERADAIAQLMTQEQGKPLTEAR-VEVLSAADIIEWFA 142 Query: 146 GWADKIQGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 ++ G+ +P + EP+G A TPWNFP+ +V KL+ AL G + ++K Sbjct: 143 DEGRRVYGRIVPPRNLGAQQTVVKEPVGPVAAFTPWNFPVNQVVRKLSAALATGCSFLVK 202 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKL 264 E+TP + L +AG P GV+ +V G + + + HP I K+ FTGST VGK Sbjct: 203 APEETPASPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQ 262 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + A ++KR T+ELGG P IV DAD+ LAV+ A F N GQ C + +R V Sbjct: 263 LASLAGL-HMKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLVHN 321 Query: 325 QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS 384 + EF R V++A+ VG+ + T G + ++ + +I++ +K GA +E GG Sbjct: 322 SIRDEFTRALVKHAEGLKVGNGLEEGTTLGALANPRRLTAMASVIDNARKVGASIETGGE 381 Query: 385 AMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 + +G F PTV + V + + E FGPV I F +EE I AN +GL F Sbjct: 382 RIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKLEEAIAEANRLPFGLAGYAF 441 Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 T++ L LE G +WIN + + PFGG K SG G E G AL Y K+VT Sbjct: 442 TRSFANVHLLTQRLEVGMLWINQPATPWPEMPFGGVKDSGYGSEGGPEALEPYLVTKSVT 501 Query: 505 I 505 + Sbjct: 502 V 502 >5VBF-A nrPDB Length = 478 Score = 257 bits (657), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 160/473 (33%), Positives = 236/473 (49%), Gaps = 6/473 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 +++I+ +H++ + +P T + E+ D+D AV+AA AF WR Sbjct: 8 RLYIDGRFHDADGRRTQPVVDPGTTRVLGELPHATAHDIDAAVQAAHRAFVT---WRHES 64 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 L R LL + A L T+ TMD GKP A ++ L + A + Sbjct: 65 PLVRSDLLRRAAALARERAETIGRHITMDQGKPLREAI-AEVVSAAEQLEWHAEEGRRTY 123 Query: 153 GKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G+ +P +V+ EPIGVC A +PWNFP + K+A AL G T+VLK E++P Sbjct: 124 GRVVPARSPDVMQTVLREPIGVCAAFSPWNFPFSQAMHKIAAALASGCTLVLKGPEESPS 183 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L L +AG PPG +NIV G V + PQ+ KI+FTGS VGK + A+ Sbjct: 184 AIVALAQLFHDAGLPPGCLNIVWGVPGDVSKQLIEAPQVRKISFTGSVPVGKQLAALAA- 242 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 S +KR+T+ELGG P +VCADAD++ A F N GQ C + +R FV+ + FV Sbjct: 243 SLMKRMTMELGGHAPVLVCADADVERAAAMLAAYKFRNAGQVCVSPTRFFVQRAAFDRFV 302 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 ++ VG D GP ++ D+I + +GA++ GG + G Sbjct: 303 CAYLDAVGTIRVGYGLDAGVTMGPLAHARRVDEIDAFVADATAKGAQIATGGMRLPGPGH 362 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 + PTV T + R+ +E FGP+ I+ F +++ + AN +GL + FT + A Sbjct: 363 YFAPTVVLGPTRDTRLMNDEPFGPIVGIVPFDDLDDALAEANRLPFGLASYAFTTSARNA 422 Query: 452 LKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 +++ ALE+G V IN + A+ PFGG K SG G E G A Y K VT Sbjct: 423 HRISRALEAGMVNINHFGMGPAEIPFGGVKDSGFGSEGGMEAFDGYLVTKFVT 475 >4DNG-A nrPDB Length = 485 Score = 253 bits (645), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 160/480 (33%), Positives = 253/480 (52%), Gaps = 12/480 (2%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 K FIN +W +SG+ NP + I ++ A + AQ A + W + Sbjct: 6 LNKSFINGKWTGGESGRTEDILNPYDQSVITTASLATGKQLEDAFDIAQKAQKE---WAK 62 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 R +L + + +R + + +TG + + I+LE I L + + Sbjct: 63 STTEDRKAVLQKARGYLHENRDDIIMMIARETGGTIIKST-IELEQTIAILDEAMTYTGE 121 Query: 151 IQG-KTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQ 208 + G K +P+D + P+GV +I+P+NFP+ + + +APA+ GN++V KP Q Sbjct: 122 LGGVKEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGNSVVHKPDIQ 181 Query: 209 TPLTA-LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 T ++ + + AG P GV+N++ +G + ++P I+FTGST VG+ + E Sbjct: 182 TAISGGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGMLTNPIPRLISFTGSTAVGRHIGE 241 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 A R+ KR+ LELGG NP V +DAD+D AV+ A G F +QGQ C +R+ V + VY Sbjct: 242 IAGRA-FKRMALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQDVY 300 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 EFV + K+ P GD D KT GP I+++Q +K LE+IE K +G +L G + Sbjct: 301 DEFVEKFTARVKQLPYGDQTDPKTVVGPLINERQIEKALEIIEQAKTDGIELAVEGKRV- 359 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G + P VF +N +IA+ E+F P+ I+K S +E I AN T+YGL++AVFT + Sbjct: 360 --GNVLTPYVFVGADNNSKIAQTELFAPIATIIKAGSDQEAIDMANDTEYGLSSAVFTSD 417 Query: 448 LDKALKLASALESGTVWINCYNALYA-QAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 L+K K A ++SG +N + + FGG K SG GR + + E+T K ++I+ Sbjct: 418 LEKGEKFALQIDSGMTHVNDQSVNDSPNIAFGGNKASGVGRFGNPWVVEEFTVTKWISIQ 477 >2J5N-A nrPDB Length = 516 Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 174/502 (34%), Positives = 259/502 (51%), Gaps = 27/502 (5%) Query: 5 NGAVENGQPDRKPPALPRPIRNLEVKFTK---IFINNEWHESKSGKKFATCNPST-REQI 60 N +E Q + A+ +R + +F + ++I EW ++K ++ + NPS E + Sbjct: 8 NEPIETFQTEEARRAMREALRRVREEFGRHYPLYIGGEWVDTK--ERMVSLNPSAPSEVV 65 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 120 + K + + A+EAA AF+ W + D R RLL + A L+ R + L A Sbjct: 66 GTTAKAGKAEAEAALEAAWKAFKTWKDWPQED---RSRLLLKAAALMRRRKRELEATLVY 122 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI-----PTDDNVVCFTRHEPIGVCG 175 + GK ++ A D+ I + Y+A A + + + P +DN + P+G Sbjct: 123 EVGKNWVEAS-ADVAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYV---PLGAGV 178 Query: 176 AITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPG 235 I PWNFP+ + + + GNT++ KPAE + + + EAGFPPGVVN +PG Sbjct: 179 VIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPG 238 Query: 236 FGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR-----SNLKRVTLELGGKNPCIVC 290 G VGA + HP+I I FTGS EVG + EAA R + KR +E GGK+ IV Sbjct: 239 VGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTWFKRAYVETGGKDAIIVD 298 Query: 291 ADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVK 350 AD DLA E + QGQ C+AASR+ + + Y + R ++ A++ VG P + Sbjct: 299 ETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVG-PAEEN 357 Query: 351 TEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKE 410 + GP + +Q K+L IE GK EG +L GG +E +G FI PTVF+EV RIA+E Sbjct: 358 PDLGPVVSAEQERKVLSYIEIGKNEG-QLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQE 416 Query: 411 EIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN--CY 468 EIFGPV +++ K E ++ AN T YGLT V+++ + G ++ N Sbjct: 417 EIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVYSRKREHLEWARREFHVGNLYFNRKIT 476 Query: 469 NALYAQAPFGGFKMSGNGRELG 490 AL PFGGFK+SG + G Sbjct: 477 GALVGVQPFGGFKLSGTNAKTG 498 >1T90-A nrPDB Length = 486 Score = 250 bits (638), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 166/484 (34%), Positives = 249/484 (51%), Gaps = 11/484 (2%) Query: 28 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 87 E++ K +IN EW ESK+ + NP+T+E +C+V K D+D A + A AF+ Sbjct: 2 EIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFKT--- 58 Query: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147 W ++ R R+L L+ + + LA L T++ GK A ++ I + + AG Sbjct: 59 WSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALG-EVGRGIENVEFAAGA 117 Query: 148 ADKIQGKTIPT-DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 206 + G ++ + +V PIGV G I P+NFP+++ W A+ GNT +LKP+ Sbjct: 118 PSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPS 177 Query: 207 EQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 E+TPL L L ++AG P GV N+V G V I HP+I I+F GS VG+ V Sbjct: 178 ERTPLLTEKLVELFEKAGLPKGVFNVVYGAHDVVN-GILEHPEIKAISFVGSKPVGEYVY 236 Query: 267 EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQV 326 + S NLKRV G KN IV DA+L+ V F + G+ C A + V VEE + Sbjct: 237 KKGSE-NLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGI 295 Query: 327 YSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG-SA 385 EF+ + E +G+ D GP I + + L IE G +EGA+L C G Sbjct: 296 ADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKRTLSYIEKGLEEGARLVCDGREN 355 Query: 386 MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 + D G F+ PT+F VT M I K+EIF PV +++ K+++E I+ AN +++ A +FT Sbjct: 356 VSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKNLKEAIEIANKSEFANGACLFT 415 Query: 446 KNLDKALKLASALESGTVWINC-YNALYAQAPFGGFKMS--GNGRELGEYALAEYTEVKT 502 N + +++G + IN A A PF G+K S G G+ ++ YT K Sbjct: 416 SNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFFGTLHANGKDSVDFYTRKKV 475 Query: 503 VTIK 506 VT + Sbjct: 476 VTAR 479 >3RH9-A nrPDB Length = 506 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 170/472 (36%), Positives = 248/472 (52%), Gaps = 9/472 (1%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 +I W +S G F NP+T I +V + DV AVEA Q A + +PW Sbjct: 15 YIGGRWKDSAGGATFDVYNPATGSVIAKVPSMPEEDVVAAVEAGQSALRLTNPW---PIE 71 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 +R + L + D ++ +R + + M+ GKP+ A +++ Y A + Sbjct: 72 TRRKWLEDIRDGLKENREEIGRILCMEHGKPWKEAQG-EVDYAAGFFDYCAKHISALDSH 130 Query: 155 TIPTDDNVVCFTRH-EPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213 TIP +T H P+GV G I PWNFP+ M+ KL+ AL G V+KPA +TPLT Sbjct: 131 TIPEKPKDCTWTVHYRPVGVTGLIVPWNFPIGMIAKKLSAALAAGCPSVIKPASETPLTM 190 Query: 214 LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG-KLVKEAASRS 272 + S++ + P G+VN+V G +G + H + ++FTGSTEVG KL+ + A + Sbjct: 191 IAFFSVMDKLDLPDGMVNLVMGKASVIGKVLCEHKDVPMLSFTGSTEVGRKLIVDTAEQ- 249 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 +K++ LELGG P IV DADL+ A + F GQ C A+R+FV E+V F + Sbjct: 250 -VKKLALELGGNAPFIVFDDADLEAAADNLIANKFRGGGQTCVCANRIFVHEKVADAFGQ 308 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME-DKGL 391 + E K VGD + + GP I+++ FDK+ ++ +GA L G E GL Sbjct: 309 KLAERVNKMTVGDGMNDGIDIGPLINKQGFDKVKRHLQDALDKGASLVAGKQPAELGDGL 368 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 F PTV V M +EE FGP+ P+ F++ EEVI N T++GL + VFT + ++A Sbjct: 369 FFPPTVVQGVDREMCCYQEETFGPLVPMALFRTEEEVIDAGNDTEFGLASYVFTADAERA 428 Query: 452 LKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 ++A+ L G V N +APFGG K SG GRE G L E+ E +TV Sbjct: 429 QRVAAGLRFGHVGWNTGTGPTPEAPFGGMKASGIGREGGLEGLFEFVEAQTV 480 >2QE0-A nrPDB Length = 475 Score = 245 bits (626), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 160/486 (32%), Positives = 248/486 (51%), Gaps = 28/486 (5%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP-WRRL 91 K ++N EW S++ K P++ ++ V +VD +A+ + P WR L Sbjct: 6 KNYVNGEWKLSENEIKI--YEPASGAELGSVPAMSTEEVDYVYASAK----KAQPAWRAL 59 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT---LRYFAGWA 148 + R LH++AD++ RD+ + A+ + + K + A + +RT + Y A Sbjct: 60 SYIERAAYLHKVADILMRDKEKIGAILSKEVAKGYKSA----VSEVVRTAEIINYAAEEG 115 Query: 149 DKIQGKTI------PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMV 202 +++G+ + + R EP+G+ AI+P+N+P+ + K+APAL GN + Sbjct: 116 LRMEGEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIA 175 Query: 203 LKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG 262 KP Q ++ L L EAG P GV N + G G +G I H +N I FTGST +G Sbjct: 176 FKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIG 235 Query: 263 KLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFV 322 + + + A ++ + L LGGK+ IV DADL+L + G F GQ CTA RV V Sbjct: 236 ERIGKMA---GMRPIMLALGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVLV 292 Query: 323 EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECG 382 E V E V + E +G+P D + P ID K D + LI +GA Sbjct: 293 MESVADELVEKIREKVLALTIGNPED-DADITPLIDTKSADYVEGLINDANDKGA---TA 348 Query: 383 GSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 + ++ +G I P +F +VT +MR+A EE FGPV PI++ S+EE I+ +N ++YGL A+ Sbjct: 349 LTEIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYGLQAS 408 Query: 443 VFTKNLDKALKLASALESGTVWINCYNALYAQA-PFGGFKMSGNGRELGEYALAEYTEVK 501 +FT + +A +A LE GTV IN PF G K SG G + +Y++ T VK Sbjct: 409 IFTNDFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAMTTVK 468 Query: 502 TVTIKL 507 +V + Sbjct: 469 SVVFDI 474 >2W8P-A nrPDB Length = 487 Score = 243 bits (620), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 156/422 (36%), Positives = 230/422 (54%), Gaps = 9/422 (2%) Query: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147 WR + A R LL + +L+ +++ LA + T ++GKP A L L +F+ Sbjct: 64 WREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAF-FLEWFSEE 122 Query: 148 ADKIQGKTI--PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKP 205 A ++ G I P D + +PIGV ITPWNFP M+ K+ AL G T+V+KP Sbjct: 123 ARRVYGDIIHTPAKDRRALVLK-QPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKP 181 Query: 206 AEQTPLTALYLGSLIKEAGFPPGVVNIVP---GFGPTVGAAISSHPQINKIAFTGSTEVG 262 AE TP +AL L L +AG P GV N++P VG AI + P ++KI+FTGST G Sbjct: 182 AEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTG 241 Query: 263 KLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFV 322 K++ A+ S +KRV++ELGG P IV A++D AV A F N GQ +++ V Sbjct: 242 KILLHHAANS-VKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTAVCSNQFLV 300 Query: 323 EEQVYSEFVRRSVEYAKKR-PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLEC 381 + ++ FV+ E KK VG+ F+ T QGP I++K +K+ + + +GA + Sbjct: 301 QRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVT 360 Query: 382 GGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTA 441 GG + F +PT+ VT +M EE FGP+ P++KF + EE I AN+ D GL Sbjct: 361 GGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAG 420 Query: 442 AVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 ++++ + ++A LE G V +N + PFGG K SG GRE +Y + EY E+K Sbjct: 421 YFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELK 480 Query: 502 TV 503 V Sbjct: 481 YV 482 >3PRL-A nrPDB Length = 505 Score = 243 bits (620), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 162/483 (33%), Positives = 249/483 (51%), Gaps = 18/483 (3%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 I N EW ES++G++ + P++ + + + +V+ A++ A+ A + W+ Sbjct: 14 ILRNGEWVESRTGERISISAPASGVALGSIPALSQEEVNDAIQGAKDAQKI---WKIRPI 70 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 R LL+ ADL+E + + L + KP A ++ +R+ A A ++ G Sbjct: 71 HERVDLLYAWADLLEERKEIIGELIMHEVAKPKKSAIG-EVSRTADIIRHTADEALRLNG 129 Query: 154 KTIPTD------DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 +T+ D + EP+GV AI+P+N+P+ + K+APAL GNT+V KPA Sbjct: 130 ETLKGDQFKGGSSKKIALVEREPLGVVLAISPFNYPVNLAAAKIAPALVTGNTVVFKPAT 189 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 Q L+ + + + +AG P G++ +V G G +G + HP I+ I FTG T G+ + E Sbjct: 190 QGSLSGIKMVEALADAGAPEGIIQVVTGRGSVIGDHLVEHPGIDMITFTGGTTTGERISE 249 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 ++ + V LELGGK+P IV DADL L G F GQ CTA RVFV++ V Sbjct: 250 ---KAKMIPVVLELGGKDPAIVLDDADLKLTASQIVSGAFSYSGQRCTAIKRVFVQDSVA 306 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 + V E ++ VG P D + P ID+K I LI+ + GA L G + Sbjct: 307 DQLVANIKELVEQLTVGSPED-DADITPVIDEKSAAFIQGLIDDALENGATLLSGN---K 362 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 +G + PT+ +VT MR+A EE FGPV PI++ K E I +N +DYGL A++FTK+ Sbjct: 363 RQGNLLSPTLLDDVTPAMRVAWEEPFGPVLPIIRVKDANEAISLSNQSDYGLQASIFTKD 422 Query: 448 LDKALKLASALESGTVWINCYNALYAQA-PFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 D+A+ + LE GTV IN PF G K SG G + + +L T + + Sbjct: 423 TDRAINIGKHLEVGTVHINAKTERGPDHFPFLGVKKSGLGVQGIKPSLLSMTRERVTVLN 482 Query: 507 LGD 509 L + Sbjct: 483 LAE 485 >3ROS-A nrPDB Length = 484 Score = 226 bits (575), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 134/452 (29%), Positives = 220/452 (48%), Gaps = 8/452 (1%) Query: 48 KFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLV 107 K+ + NP T E + +D+A+ A +++ WR + SR +LH +A+ + Sbjct: 5 KYQSVNPYTNEAFASYDNPTSKQIDEAINLAHALYKK---WRHEEPASRAEILHDIANAL 61 Query: 108 ERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR 167 + LA + T++ GK L ++E C+ Y+A ++ T D + Sbjct: 62 KEHEDELAKMMTLEMGK-LLSESKEEVELCVSICNYYADHGPEMLKPTKLNSDLGNAYYL 120 Query: 168 HEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPP 227 + GV A PWNFPL ++ AP GN ++LK A P +A +IK AG P Sbjct: 121 KQSTGVIMACEPWNFPLYQVIRVFAPNFIVGNPILLKHAHNVPGSAALTAKIIKRAGAPE 180 Query: 228 G-VVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNP 286 G ++N+ P + A I + P+I +A TGS G V EAA + NLK+ T+ELGG + Sbjct: 181 GSLINLYPSYDQL--ADIIADPRIQGVALTGSERGGSAVAEAAGK-NLKKSTMELGGNDA 237 Query: 287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 IV DAD + + +N GQ CT++ R+ VE+ Y E + GDP Sbjct: 238 FIVLDDADPQVLRNVLNDARTYNDGQVCTSSKRIIVEKSRYDEVLHELKNVFSNLKAGDP 297 Query: 347 FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMR 406 + T P +K +K+ ++ GAK+ ++ KG F +PT+ +++ + Sbjct: 298 LEADTTLPPMNSEKAKEKLEAQVKEAIDAGAKVFYQYPEIDSKGAFFRPTILTDIAKDNP 357 Query: 407 IAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN 466 + +E+FGP+ + + I+ AN + YGL ++V ++D+A K+++ +E+G IN Sbjct: 358 VFDKEVFGPIAEVFVVEDDNAAIQLANDSSYGLGSSVIGSDIDRAKKVSAQIETGMTVIN 417 Query: 467 CYNALYAQAPFGGFKMSGNGRELGEYALAEYT 498 + PFGG K SG GREL L + Sbjct: 418 GRWITSGELPFGGIKKSGYGRELSGLGLMAFV 449 >4PXN-A nrPDB Length = 525 Score = 226 bits (575), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 151/476 (31%), Positives = 237/476 (49%), Gaps = 15/476 (3%) Query: 45 SGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLA 104 SG + +P+ + I EV E D ++ + A F W + A RG ++ Q+ Sbjct: 49 SGPTVTSTSPTNNQVIAEVVEASVHDYEEGMRAC---FDAAKTWMAIPAPKRGEIVRQIG 105 Query: 105 DLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDD-NVV 163 D + L L +++ GK L +++ I Y G + ++ G IP++ N + Sbjct: 106 DALRAKLHHLGRLVSLEMGK-ILPEGIGEVQEIIDMCDYAVGLSRQLNGSIIPSERPNHM 164 Query: 164 CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYL----GSL 219 P+GV G IT +NFP +L W AL CGN +V K A TPL + + S+ Sbjct: 165 MMEVWNPLGVVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAMTKIVASV 224 Query: 220 IKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTL 279 +++ P + G G +G AI+ +I ++FTGST G +V++ S + + L Sbjct: 225 LEKNNLPGAIFTSFCG-GTEIGQAIALDIRIPLVSFTGSTRAGLMVQQQVS-ARFGKCLL 282 Query: 280 ELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAK 339 EL G N IV DAD+ LAV GQ CT R+ + E +Y F+ + VE K Sbjct: 283 ELSGNNAIIVMDDADIQLAVRSVLFAAVGTAGQRCTTCRRLILHENIYQTFLDQLVEVYK 342 Query: 340 KRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFS 399 + +GDP + T GP + L+ I++ K +G K+ GGSA+E +G F++PT+ Sbjct: 343 QVRIGDPLEKGTLLGPLHTPASKENFLKGIQTIKSQGGKILFGGSAIESEGNFVQPTIV- 401 Query: 400 EVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLAS--A 457 E+T + + KEE+FGPV ++KF++++E I+ NS GL++++FTK D K Sbjct: 402 EITPSAPVVKEELFGPVLYVMKFQTLKEAIEINNSVPQGLSSSIFTKRPDIIFKWLGPHG 461 Query: 458 LESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP 512 + G V +N N FGG K +G GRE G + +Y T TI G + P Sbjct: 462 SDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRATCTINYGSELP 517 >4OGD-A nrPDB Length = 465 Score = 223 bits (569), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 147/460 (31%), Positives = 223/460 (48%), Gaps = 11/460 (2%) Query: 49 FATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALS-RGRLLHQLADLV 107 + T P T E + + + +E A + +++ WR+ D L R LHQ+A+++ Sbjct: 3 YQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKK---WRKEDHLEERKAQLHQVANIL 59 Query: 108 ERDRATLAALETMDTGKPFLHAFF-IDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFT 166 RDR A + T D GK F A +DL C Y+A AD+ T D+ + Sbjct: 60 RRDRDKYAEIMTKDMGKLFTEAQGEVDL--CADIADYYADKADEFLMSTPLETDSGQAYY 117 Query: 167 RHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFP 226 + GV A+ PWNFP ++ AP GN MVLK A P +A L+ EAG Sbjct: 118 LKQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEAGAE 177 Query: 227 PG-VVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKN 285 G + N+ + + + + ++ + TGS G + E A + NLK+ TLELGG + Sbjct: 178 AGSITNLFISYDQV--SQVIADKRVVGVCLTGSERGGASIAEEAGK-NLKKTTLELGGDD 234 Query: 286 PCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGD 345 I+ DAD D + + +N GQ CT++ R V ++ Y F + K GD Sbjct: 235 AFIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGD 294 Query: 346 PFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNM 405 P D +T P + +L+ I+ GA+L GG A++ G F+ PT+ + +T + Sbjct: 295 PMDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEAIDHPGHFVMPTIIAGLTKDN 354 Query: 406 RIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWI 465 I +EIFGPV I K S EE I+ AN ++YGL +F+ N + A +A+ +E+G +I Sbjct: 355 PIYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFI 414 Query: 466 NCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 N + PFGG K SG GREL E + + I Sbjct: 415 NSGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEHLIYI 454 >3VZ0-A nrPDB Length = 459 Score = 222 bits (565), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 147/422 (34%), Positives = 210/422 (49%), Gaps = 7/422 (1%) Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFF-IDLEGCIRTLRYF 144 + W+ R ++ + ADL+ RDR A+L + GK A ID+ I L ++ Sbjct: 42 TDWKLRSIAQRKEIVSRAADLLRRDRQHHASLIATEMGKALPDALEEIDVTADI--LSFY 99 Query: 145 AGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 A A++ T ++P+G+ I PWNFP L P L GN ++ K Sbjct: 100 ANGAEEFLAPTPLKVKTGQAKIINQPLGIIYCIEPWNFPYYQLARVAGPNLMAGNVVIAK 159 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGV-VNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGK 263 A P AL L +AG P G NI A + +I +A TGS E Sbjct: 160 HAPNVPQCALAFEKLFHDAGAPVGAYANIF--LDNDQSAELIKDERIRGVALTGS-ERAG 216 Query: 264 LVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 A + + LK+ T+ELGG + IV DADLDLAV+ A G F N GQ CTAA R+ V Sbjct: 217 QAVAAQAGAALKKDTMELGGSDAFIVLDDADLDLAVKWAVWGRFANNGQVCTAAKRMIVH 276 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 E+VY F+ + +G+P D T GP + + L+ K GA L GG Sbjct: 277 EKVYDAFLDGLKTAITRFRIGNPLDRDTTHGPMSSLRAMELALDQTAEAVKGGATLVAGG 336 Query: 384 SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 M+ KG F++PT+ ++V+ + + +EIFGPV + K S + I AN + YGL AV Sbjct: 337 KRMDRKGFFMEPTILTDVSKDNPVFYQEIFGPVAVVHKVASEQAAIDLANDSPYGLGGAV 396 Query: 444 FTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 F++++ +A K+A +E+G V+IN A + PFGG K SG GREL + E+ K V Sbjct: 397 FSRDIARAEKVAEQVETGMVFINTATAAAPELPFGGIKNSGFGRELSFLGIEEFINRKLV 456 Query: 504 TI 505 I Sbjct: 457 RI 458 >2JG7-A nrPDB Length = 510 Score = 219 bits (557), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 142/484 (29%), Positives = 235/484 (48%), Gaps = 16/484 (3%) Query: 37 NNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSR 96 N W SG+ + P+ E I V + + ++ V+ + A++ W + A R Sbjct: 27 NGSW--GGSGEVITSYCPANNEPIARVTQATLAEYEETVQKTREAWKM---WADIPAPKR 81 Query: 97 GRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI 156 G ++ Q+ D + + L +L +++ GK ++ +++ + Y G + I G + Sbjct: 82 GEIVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVG-EVQEYVDVCDYAVGLSRMIGGPVL 140 Query: 157 PTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALY 215 P++ + P+G+ G IT +NFP+ + W A AL CGN + K A TPLT++ Sbjct: 141 PSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALTCGNVCLWKGAPTTPLTSVA 200 Query: 216 LGSLIKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + ++ E P + ++ G G +G A++ +++ ++FTGST VGK+V + Sbjct: 201 VTKIVAEVLEQNNLPGAICSMTCG-GADIGTAMAKDERVDLLSFTGSTHVGKMVAMMV-Q 258 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 R LELGG N IV DADL+L V A GQ CT R+ + E V+ V Sbjct: 259 ERFGRKLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESVHDAVV 318 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 R + K+ +GDP+D T GP ++ D+ L IE K++G L CGG M+ G Sbjct: 319 ERIAKAYKQVRIGDPWDPSTLYGPLHTKQAVDQYLAAIEQAKQQGGTLVCGGKVMDRPGN 378 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 +++PT+ + + + I E F P+ +LKFK+ EE N GL++++FTK+L + Sbjct: 379 YVEPTIITGLAHDAPIVHTETFVPILYVLKFKTEEEAFAWNNEVQQGLSSSIFTKDLGRV 438 Query: 452 LKLAS--ALESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 + + G V +N + FGG K +G GRE G + +Y T TI Sbjct: 439 FRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYS 498 Query: 509 DKNP 512 P Sbjct: 499 KDLP 502 >3EFV-A nrPDB Length = 462 Score = 218 bits (555), Expect = 5e-57, Method: Compositional matrix adjust. Identities = 142/453 (31%), Positives = 221/453 (48%), Gaps = 6/453 (1%) Query: 51 TCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERD 110 + NP+T + + + + +++ A+ A F++ W+ R + L + + Sbjct: 11 SVNPATGQTLAAMPWANAQEIEHALSLAASGFKK---WKMTSVAQRAQTLRDIGQALRAH 67 Query: 111 RATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEP 170 +A T + GKP A ++ ++A + +N + P Sbjct: 68 AEEMAQCITREMGKPIKQAR-AEVTKSAALCDWYAEHGPAMLNPEPTLVENQQAVIEYRP 126 Query: 171 IGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVV 230 +GV AI PWNFPL ++ P L GN+ +LK A A + ++ EAG P GV Sbjct: 127 LGVILAIMPWNFPLWQVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEAGTPAGVY 186 Query: 231 NIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVC 290 V V I+ P+I + TGS A + + LK+ LELGG +P IV Sbjct: 187 GWVNANNEGVSQMIND-PRIAAVTVTGSVRA-GAAIGAQAGAALKKCVLELGGSDPFIVL 244 Query: 291 ADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVK 350 DADL+LAV+ A G + N GQ C AA R VEE + F R V A +GDP + Sbjct: 245 NDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAFTDRFVAAAAALKMGDPLVEE 304 Query: 351 TEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKE 410 + GP D++ + +++ EGA+L GG + +G + TV ++VT +M ++ Sbjct: 305 NDLGPMARFDLRDELHQQVQASVAEGARLLLGGEKIAGEGNYYAATVLADVTPDMTAFRQ 364 Query: 411 EIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNA 470 E+FGPV I K + AN +++GL+A +FT + A ++A+ LE G V+IN Y+A Sbjct: 365 ELFGPVAAITVAKDAAHALALANDSEFGLSATIFTADDTLAAEMAARLECGGVFINGYSA 424 Query: 471 LYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 A+ FGG K SG GREL + L E+ V+TV Sbjct: 425 SDARVAFGGVKKSGFGRELSHFGLHEFCNVQTV 457 >3VZ3-A nrPDB Length = 457 Score = 217 bits (553), Expect = 9e-57, Method: Compositional matrix adjust. Identities = 144/464 (31%), Positives = 224/464 (48%), Gaps = 10/464 (2%) Query: 45 SGKKFATCNPSTREQICEVEEGDKP-DVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQL 103 S AT NP+T E IC+ + P ++D + AQ AFQ +RR R + L Sbjct: 2 SHMAIATINPTTGE-ICQRFKALTPAEIDAKLAKAQEAFQ---AYRRTSFSQRRQWLENA 57 Query: 104 ADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVV 163 A ++ERD + A + T + GK A + E RY+A ++ Sbjct: 58 AAILERDTSKFAEIMTTEMGKTHQSAI-AEAEKSALVCRYYAEHGEQFLANEYTETQATE 116 Query: 164 CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA 223 + ++P+G+ A+ PWNFP + APAL GN VLK A P AL + ++++ A Sbjct: 117 SYVCYQPLGILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAA 176 Query: 224 GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGG 283 GFP GV + G + + P++ TGS G + A + +K LELGG Sbjct: 177 GFPEGVFQTLL-IGASQVEQVIKDPRVKAATLTGSEPAGASLASLAGQ-EIKPTLLELGG 234 Query: 284 KNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRR-SVEYAKKRP 342 +P +V ADLD AVE N GQ AA R + E + +EF+ + +++A + Sbjct: 235 SDPFVVFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLK- 293 Query: 343 VGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVT 402 +GDP +T+ GP + I ++ GAK+ GG ++ G F PT+ +E+ Sbjct: 294 IGDPMAPETDIGPLATEGILQDISRQVDQAVAAGAKILLGGRPLDRAGYFYPPTILTEIP 353 Query: 403 DNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGT 462 +I +EE+F PV + K +++ I AN +GL A+ +T + + + L++G Sbjct: 354 PGAKILQEELFAPVAMVFTVKDLDQAIALANDIPFGLGASAWTNDPAEQQRFIQELDAGA 413 Query: 463 VWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 V+IN + PFGG K SG GRELG + + KTV +K Sbjct: 414 VFINGMVKSDPRLPFGGTKRSGYGRELGLAGIRTFVNAKTVWLK 457 >1UXV-A nrPDB Length = 501 Score = 213 bits (542), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 153/483 (31%), Positives = 239/483 (49%), Gaps = 28/483 (5%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPW--RRLD 92 ++ EW SG++ +P I +V + +V++ ++ V F+RG W R + Sbjct: 22 YLAGEW--GGSGQEIEVKSPIDLATIAKVISPSREEVERTLD---VLFKRGR-WSARDMP 75 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R +L + AD++ER+ A + M+ GKP A +++ + LR KI Sbjct: 76 GTERLAVLRKAADIIERNLDVFAEVLVMNAGKP-KSAAVGEVKAAVDRLRLAELDLKKIG 134 Query: 153 GKTIPTD---DNVVC--FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 G IP D D + R EP+GV AITP+N+PL V K+ + GN +V+KP+ Sbjct: 135 GDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSI 194 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIV--PGFGPTVGAAISSHPQINKIAFTGSTEVGKLV 265 PL A + +AGFPP + ++ PG I + ++ ++FTGSTEVG+ V Sbjct: 195 SDPLPAAMAVKALLDAGFPPDAIALLNLPG---KEAEKIVADDRVAAVSFTGSTEVGERV 251 Query: 266 KEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQ 325 + +K+ +ELGG +P IV DADLDLA + +G++ GQ C A V E Sbjct: 252 VKV---GGVKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERP 308 Query: 326 VYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA 385 VY + V + VGDP D + GP I D+++ IE ++G ++ GG Sbjct: 309 VYGKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRR 368 Query: 386 MEDKGLFIKPTVFSEVTD---NMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 + +++PT+ D +M + K E+F PV ++ K +++ I+ AN YGL AA Sbjct: 369 LGPT--YVQPTLVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAA 426 Query: 443 VFTKNLDKALKLASALESGTVWINCY-NALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 VF +++ K + LE G ++IN PFGG K SG RE YA+ T K Sbjct: 427 VFGRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYK 486 Query: 502 TVT 504 T+ Sbjct: 487 TIV 489 >5N5S-A nrPDB Length = 515 Score = 212 bits (539), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 140/401 (34%), Positives = 209/401 (52%), Gaps = 16/401 (3%) Query: 114 LAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTD-----DNVVCFTRH 168 +A TM++GKP A ++ I T + A + +I G+ IP D + + Sbjct: 118 IAQTLTMESGKPIKDARG-EVTRTIDTFQVAAEESVRIYGEHIPLDISARNKGLQGIVKK 176 Query: 169 EPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLI-KEAGFPP 227 PIG ++PWNFPL ++ K+APA+ G VLKPA +TPL+AL LG ++ K P Sbjct: 177 FPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCPFVLKPASRTPLSALILGEILHKIEELPL 236 Query: 228 GVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPC 287 G +I+P + + + FTGS +G +K +R+ K+V +ELGG PC Sbjct: 237 GAFSILP-VSREDADMFTVDERFKLLTFTGSGPIGWDMK---ARAGKKKVVMELGGNAPC 292 Query: 288 IVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 IV DLD ++ G F+ GQ C R++V E++Y E V KK +G+P Sbjct: 293 IVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQRLYVHERLYDEVKEGFVAAVKKLKMGNP 352 Query: 347 FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMR 406 F+ T GP I + I + ++ +G KL GG+ KG FI+PTV +V Sbjct: 353 FEEDTYLGPMISESAAKGIEDWVKEAVAKGGKLLTGGNR---KGAFIEPTVIEDVPIEAN 409 Query: 407 IAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN 466 KEEIFGPV + K+ +E +K N+T YGL + +FTK+L+KA +E G V +N Sbjct: 410 ARKEEIFGPVVLLYKYSDFKEAVKECNNTHYGLQSGIFTKDLNKAFYAFEHMEVGGVILN 469 Query: 467 CYNALYAQA-PFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 AL + P+GG K SG RE +YA+ + E K + ++ Sbjct: 470 DSPALRVDSQPYGGLKDSGIQREGVKYAMDDMLETKVLVMR 510 >5TJR-A nrPDB Length = 531 Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 145/471 (30%), Positives = 235/471 (49%), Gaps = 15/471 (3%) Query: 43 SKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQ 102 + +G+ NPST E + +V D+ + +A++AA+ AF WR R ++L + Sbjct: 47 ADTGRTADVFNPSTGEAVRKVPLADRETMQQAIDAAKAAF---PAWRNTPPAKRAQVLFR 103 Query: 103 LADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK-TIPTDDN 161 L+E + + L + + GK A +L+ I + Y + ++G+ + N Sbjct: 104 FKQLLEANEERIVKLISEEHGKTIEDAAG-ELKRGIENVEYATAAPEILKGEYSRNVGPN 162 Query: 162 VVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIK 221 + ++ +PIGV ITP+NFP ++ +W A+ CGNT +LKP+E+ P + L + L Sbjct: 163 IDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPSSTLLIAELFH 222 Query: 222 EAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLEL 281 EAG P GV+N+V G V A I + P++ ++F GST + + + ++ KRV Sbjct: 223 EAGLPKGVLNVVHGDKGAVDALIEA-PEVKALSFVGSTPIAEYIYSEGTKRG-KRVQALG 280 Query: 282 GGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS-RVFVEEQVYSEFVRRSVEYAKK 340 G KN ++ DADLD AV + + G+ C A S V V +Q+ V++ V K Sbjct: 281 GAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQIADALVQKLVPQIKG 340 Query: 341 RPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS----AMEDKGLFIKPT 396 +G + GP + DK+ I++G +GA+L G A + G F+ T Sbjct: 341 LKIGAGTSCGLDMGPLVTGAARDKVTGYIDTGVAQGAELVVDGRGYKVAGHENGFFLGGT 400 Query: 397 VFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLAS 456 +F VT M I KEEIFGPV I++ S+EE ++ N +YG +FT++ + A Sbjct: 401 LFDRVTPEMTIYKEEIFGPVLCIVRVNSLEEAMQLINDHEYGNGTCIFTRDGEAARLFCD 460 Query: 457 ALESGTVWINC-YNALYAQAPFGGFKMS--GNGRELGEYALAEYTEVKTVT 504 +E G V +N A FGG+K S G+ G + YT+ K +T Sbjct: 461 EIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTKRKAIT 511 >4X0T-A nrPDB Length = 513 Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 145/484 (29%), Positives = 229/484 (47%), Gaps = 16/484 (3%) Query: 37 NNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSR 96 N W G+ T P+ E I V + D ++ V+ A+ A++ W + A R Sbjct: 30 NGSW--GGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWK---IWADIPAPKR 84 Query: 97 GRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI 156 G ++ Q+ D + L +L +++ GK + +++ + Y G + I G + Sbjct: 85 GEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVG-EVQEYVDICDYAVGLSRMIGGPIL 143 Query: 157 PTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALY 215 P++ + P+G+ G IT +NFP+ + W A A+ CGN + K A T L ++ Sbjct: 144 PSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVA 203 Query: 216 LGSLIK---EAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 + +I E PG + + G +G A++ ++N ++FTGST+VGK V + Sbjct: 204 VTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QE 262 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 R LELGG N I DADL L V A GQ CT A R+F+ E ++ E V Sbjct: 263 RFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVN 322 Query: 333 R-SVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 R YA+ R VG+P+D GP ++ L +E KKEG + GG M+ G Sbjct: 323 RLKKAYAQIR-VGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGN 381 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 +++PT+ + + + IA E F P+ + KFK+ EEV N GL++++FTK+L + Sbjct: 382 YVEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRI 441 Query: 452 LKLAS--ALESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 + + G V +N + FGG K +G GRE G A +Y T TI Sbjct: 442 FRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYS 501 Query: 509 DKNP 512 P Sbjct: 502 KDLP 505 >4I3V-A nrPDB Length = 488 Score = 205 bits (522), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 128/349 (36%), Positives = 188/349 (53%), Gaps = 16/349 (4%) Query: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224 FT EP+ AITP+N PL M+ K+APA+ N +V+KP E TP+TAL L ++ EAG Sbjct: 145 FTMREPLTAISAITPFNHPLNMVAHKVAPAIATNNCVVVKPTELTPMTALLLADILYEAG 204 Query: 225 FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284 PP ++++V G+ +G + ++P ++ + FTGS VGKL+ A+ ++ KR LELGG Sbjct: 205 LPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPVGKLI---AANAHYKRQVLELGGN 261 Query: 285 NPCIV---CADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKR 341 +P I+ +D DL A + A G N GQ CTA R+ +E V FV +E AK+ Sbjct: 262 DPLIILNDLSDDDLARAADLAVAGATKNSGQRCTAVKRILCQESVADRFVPLVLERAKRL 321 Query: 342 PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL--ECGGSAMEDKGLFIKPTVFS 399 GDP D T+ G I +K E + +EGA + G S G + P V Sbjct: 322 RFGDPMDRSTDLGTVIHEKAAALFEERVMRAAEEGADILYHPGRS-----GALLPPIVVD 376 Query: 400 EVTDNMRIAKEEIFGPVQPILKFKSIEE-VIKRANSTDYGLTAAVFTKNLDKALKLASAL 458 V + EE FGP+ PI++ ++ I +NST +GL++ V T + + K + L Sbjct: 377 RVPHQSDLVLEETFGPIIPIVRVPDDDDATITLSNSTAFGLSSGVCTNDYRRMQKYIAGL 436 Query: 459 ESGTVWI-NCYNALYAQAPFGGFKMSGNGRELGEY-ALAEYTEVKTVTI 505 + GTV I +PFGG K SGNG + G A+ +T VKT ++ Sbjct: 437 KVGTVNIWEVPGYRIEMSPFGGIKDSGNGYKEGVIEAMKSFTNVKTFSL 485 >4ZZ7-A nrPDB Length = 501 Score = 201 bits (511), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 139/461 (30%), Positives = 233/461 (50%), Gaps = 15/461 (3%) Query: 53 NPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRA 112 NP+T E +++ V++A+ AAQ AF WR L R R++ + +L+E+ Sbjct: 27 NPATGEIGKQLDLASTKTVEQAISAAQHAF---PTWRNTPPLKRARVMFRFKELLEQHAD 83 Query: 113 TLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK-TIPTDDNVVCFTRHEPI 171 + L + GK H +L+ I + Y G + ++G+ + + ++ +P+ Sbjct: 84 EICRLIGEEHGK-IAHDAMGELQRGIENVEYACGAPELLKGEHSRNVGPGIDSWSEFQPM 142 Query: 172 GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVN 231 GV ITP+NFP+++ +W A+ CGN VLKP+E+ P + LY+ L++EAG P GV+N Sbjct: 143 GVVAGITPFNFPVMVPLWMFPMAIVCGNCFVLKPSERDPSSTLYIAQLLQEAGLPDGVMN 202 Query: 232 IVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCA 291 +V G V A + ++ ++F GST + + + AS +N KR G KN IV Sbjct: 203 VVNGDKEAVDALLHDD-RVKAVSFVGSTPIAEYIYRTAS-ANGKRCQALGGAKNHAIVMP 260 Query: 292 DADLDLAVECAHQGVFFNQGQCCTAAS-RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVK 350 DAD+D AV F + G+ C A S V V + V + + +K VG D Sbjct: 261 DADMDNAVNQLLGAAFGSSGERCMALSVAVAVGDAAGDALVSKMTQAMQKLKVGPSTDSG 320 Query: 351 TEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA----MEDKGLFIKPTVFSEVTDNMR 406 + GP I ++ +K++ I S +++GA + G + G F+ T+ VT M Sbjct: 321 NDFGPVITRQHQEKVIGYINSAEQQGATIVVDGRQPKVPNHENGFFVGGTLIDHVTPEMT 380 Query: 407 IAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN 466 +EEIFGPV +++ ++++ + ++ +YG +FT++ + A + ++ G V IN Sbjct: 381 SYQEEIFGPVLQVVRVATMQDAMDLIDAHEYGNGTCIFTRDGEAARYFSDNIQVGMVGIN 440 Query: 467 C-YNALYAQAPFGGFKMS--GNGRELGEYALAEYTEVKTVT 504 A FGG+K S G+ G A+ YT+ KTVT Sbjct: 441 IPLPVPVAYHSFGGWKRSLFGDLHAYGPDAVRFYTKRKTVT 481 >4KNA-A nrPDB Length = 495 Score = 200 bits (508), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 143/466 (30%), Positives = 223/466 (47%), Gaps = 22/466 (4%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 T++FI+ W + +G FA+ NP T E++ E DV++AV +A+ AF + W Sbjct: 9 MTELFIDGAWVDG-AGPVFASRNPGTNERVWEGASASADDVERAVASARRAF---AAWSA 64 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 LD +R ++ + A L+ + LA + +TGKP A + + ++ Sbjct: 65 LDLDARCTIVKRFAALLVERKEALATMIGRETGKPLWEARTEVASMAAKVDISITAYHER 124 Query: 151 IQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 K P D V RH P GV P+NFP + + PAL GNT+V KP+E P Sbjct: 125 TGEKRAPMADGVAVL-RHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAP 183 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLV-KEAA 269 A + ++AG P GV+N+V G T G A+++H QI+ + FTGS++ G L+ K+ Sbjct: 184 GVARATVEIWRDAGLPAGVLNLVQGEKDT-GVALANHRQIDGLFFTGSSDTGTLLHKQFG 242 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 R + + LE+GG NP +V D+D AV A Q F + GQ CT A R+ V + + Sbjct: 243 GRPEIV-LALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGD 301 Query: 330 -FVRRSVEYAKKRPVGDPFDVKTE--QGPQIDQKQFDKIL----ELIESGKKEGAKLECG 382 FV R + A K FD + G I + +++ L+ G +++ Sbjct: 302 RFVARLADVASK-ITASVFDADPQPFMGAVISARAASRLVAAQARLVGLGASPIIEMK-- 358 Query: 383 GSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 D L +VT+ + EE FGP+ I+++ +++ I RAN T +GL+A Sbjct: 359 ---QRDPALGFVNAAILDVTNVRELPDEEHFGPLAQIVRYTDLDDAIARANDTAFGLSAG 415 Query: 443 VFTKNLDKALKLASALESGTV-WINCYNALYAQAPFGGFKMSGNGR 487 + + A+ +G V W N + APFGG SGN R Sbjct: 416 LLADDEQAWHTFRRAIRAGIVNWNRPTNGASSAAPFGGAGRSGNHR 461 >5U0M-A nrPDB Length = 497 Score = 194 bits (494), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 148/487 (30%), Positives = 229/487 (47%), Gaps = 28/487 (5%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 ++I+ W G F + P T E + + DVD AV A+ AF WRR Sbjct: 13 NVYIDGLWLPGH-GAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFL---AWRRKS 68 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R ++ +L+E ++ LA ++TGKP + ++ + + ++ Sbjct: 69 LAERQAVIEAFGELLEANKEELAHQIGLETGKPLWESR-TEVAAMMGKIPISVKAYNERT 127 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 G T RH P GV P+NFP + + PAL GNT+V KP+E TP Sbjct: 128 GHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPGV 187 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 A L ++AG P GV+N+V G G G ++ H I+ + FTGS+ VG L+ E Sbjct: 188 AELTVRLWEKAGLPDGVINLVQG-GSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGGQ 246 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE-QVYSEFV 331 K + LE+GG NP IV +DLD AV A Q F + GQ CT A R+ V + + EF+ Sbjct: 247 PEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEFL 306 Query: 332 RRSVEYAKKRPVGDPFDVKTE--QGPQIDQKQFDKILELIESGKKEGAKLECGGSAM--- 386 R VE A + V + FD + G I + +++L K + A LE G +++ Sbjct: 307 ARLVEVAARITVAE-FDADPQPFMGSVISAEAANQLL------KAQAAMLEKGATSLLEM 359 Query: 387 ----EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 D GL + P + + + +E FGP+ + ++K +E ++ AN+T YGL+A Sbjct: 360 KQLKPDTGL-LSPGIVD--ATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAG 416 Query: 443 VFTKNLDKALKLASALESGTV-WINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 + + + +L + +G V W + APFGG SGN R YA A+Y Sbjct: 417 ILSDDRKLYNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYA-ADYCAWP 475 Query: 502 TVTIKLG 508 +++ G Sbjct: 476 MASLEAG 482 >5KF0-A nrPDB Length = 485 Score = 194 bits (492), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 138/430 (32%), Positives = 211/430 (49%), Gaps = 20/430 (4%) Query: 87 PWRRLDALSRGRLL-HQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 P R L A R +L H +A ER AL ++ GKP ++ ++ I T R + Sbjct: 64 PMRELPAYRRQAVLDHCVARFRERFDELAEAL-CIEAGKP-INDSRGEVTRLIDTFRVAS 121 Query: 146 GWADKIQGKTIPTD-----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT 200 A +I G+ + + +TR PIG C I+P+NFPL + K+APAL G Sbjct: 122 EEAVRIDGEVLNLEISARAQGYTGYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCP 181 Query: 201 MVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAI-SSHPQINKIAFTGST 259 VLKPA +TP+ AL + ++ E P G +++P GA + ++ + ++FTGS Sbjct: 182 FVLKPASRTPVGALIIAEVLAETNLPKGAFSVLPAHRD--GADLFTTDERFRLLSFTGSP 239 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA--DLDLAVECAHQGVFFNQGQCCTAA 317 VG +KE A + K+V LELGG IV AD LD V+ G ++ GQ C Sbjct: 240 AVGWALKEKAGK---KKVVLELGGNAAAIVDADQFEQLDYVVDRLAFGAYYQSGQSCIGV 296 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 R+ V +Y + V + +GDP D T GP I + + ++ +++ GA Sbjct: 297 QRILVHASLYDTLRDKLVAKTRSLKMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGA 356 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 K+ GG G + T+ +V + ++E FGPV + KF ++ + R N +D+ Sbjct: 357 KIIAGGKV---DGAMFEATLLEDVGREQDLYRKEAFGPVAILEKFDRFDDALARVNDSDF 413 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYA-QAPFGGFKMSGNGRELGEYALAE 496 GL A VFT +L A + LE G V IN + P+GG K SG GRE YA+ + Sbjct: 414 GLQAGVFTDSLTHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIED 473 Query: 497 YTEVKTVTIK 506 TE + + ++ Sbjct: 474 MTEPRLMVVR 483 >5JRY-A nrPDB Length = 485 Score = 193 bits (490), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 137/430 (31%), Positives = 209/430 (48%), Gaps = 20/430 (4%) Query: 87 PWRRLDALSRGRLL-HQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 P R L A R +L H +A ER AL ++ GKP A ++ I T R + Sbjct: 64 PMRELPAYKRQAVLDHCVARFRERFDELAEAL-CIEAGKPINDAKG-EVTRLIDTFRVAS 121 Query: 146 GWADKIQGKTIPTD-----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT 200 A +I G+ + + +TR PIG C I+P+NFPL + K+APAL G Sbjct: 122 EEAVRIDGEVLNLEISARAQGYTGYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCP 181 Query: 201 MVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAI-SSHPQINKIAFTGST 259 VLKPA +TP+ AL +G ++ E P G +++P GA + ++ + ++FTGS Sbjct: 182 FVLKPASRTPVGALIIGEVLAETDLPKGAFSVLPAHRD--GADLFTTDDRFRLLSFTGSP 239 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA--DLDLAVECAHQGVFFNQGQCCTAA 317 VG +KE A + K+V LELGG IV AD LD V+ G F+ GQ C Sbjct: 240 AVGWALKEKAGK---KKVVLELGGNAAAIVDADQLDRLDYVVDRLAFGAFYQSGQSCIGV 296 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 R+ +Y + + + +GDP D T GP I + + ++ +++ GA Sbjct: 297 QRILAHADIYDALRDKLIAKTRSLKMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGA 356 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 K+ GG G + T+ V + + ++E FGP+ + KF ++ + R N +D+ Sbjct: 357 KIVAGGKV---DGAMFEATLLENVGRDQDLYRKEAFGPIAILEKFDRFDDALARVNDSDF 413 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYA-QAPFGGFKMSGNGRELGEYALAE 496 GL A VFT +L + LE G V IN + P+GG K SG GRE YA+ + Sbjct: 414 GLQAGVFTDSLAHTQQAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIED 473 Query: 497 YTEVKTVTIK 506 TE + + ++ Sbjct: 474 MTEPRLLVVR 483 >4E4G-A nrPDB Length = 521 Score = 187 bits (476), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 118/348 (33%), Positives = 186/348 (53%), Gaps = 10/348 (2%) Query: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224 ++ +P+G+ ITP+NFP ++ +W APA+ CGN +LKP+E+ P + L L+ EAG Sbjct: 157 YSIRQPVGIGAGITPFNFPGMIPMWMFAPAIACGNAFILKPSERDPSVPIRLAELMIEAG 216 Query: 225 FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGK 284 P G++N+V G V AI +HP I ++F GST + + V A+ N KR G K Sbjct: 217 LPAGILNVVNGDKGAV-DAILTHPDIAAVSFVGSTPIARYVYGTAAM-NGKRAQCFGGAK 274 Query: 285 NPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS-RVFVEEQVYSEFVRRSVEYAKKRPV 343 N I+ DADLD A + + G+ C A S V V E+ + + + V + + Sbjct: 275 NHMIIMPDADLDQAANALIGAGYGSAGERCMAISVAVPVGEETANRLIDKLVPMVESLRI 334 Query: 344 GDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME----DKGLFIKPTVFS 399 G D K + GP + ++ +I LI+SG ++GAKL G + + G FI +F Sbjct: 335 GPYTDEKADMGPVVTKEAEQRIRSLIDSGIEQGAKLVVDGRDFKLQGYENGHFIGGCLFD 394 Query: 400 EVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALE 459 +VT +M I K EIFGPV +++ ++ EE + +YG A++T++ D A AS + Sbjct: 395 DVTPDMDIYKTEIFGPVLSVVRARNYEEALSLPMKHEYGNGVAIYTRDGDAARDFASRIN 454 Query: 460 SGTVWINCYNAL-YAQAPFGGFKMS--GNGRELGEYALAEYTEVKTVT 504 G V +N + A FGG+K S G+ + G ++ +T KT+T Sbjct: 455 IGMVGVNVPIPVPLAYHSFGGWKSSSFGDLNQHGTDSIKFWTRTKTIT 502 >5J6B-A nrPDB Length = 485 Score = 187 bits (476), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 137/430 (31%), Positives = 209/430 (48%), Gaps = 20/430 (4%) Query: 87 PWRRLDALSRGRLL-HQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 P R L A R +L H +A ER AL ++ GKP ++ ++ I T R A Sbjct: 64 PLRALPAFRRQAILEHCVARFRERFDELAQAL-CIEAGKP-INDSKGEVTRLIDTFRVAA 121 Query: 146 GWADKIQGKTI-----PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT 200 + +I+G + P + + PIG C I+P+NFPL + K+APAL G Sbjct: 122 EESVRIEGGLVNLEISPRAQGYSGYYKRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCP 181 Query: 201 MVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAI-SSHPQINKIAFTGST 259 VLKPA +TP+ AL +G ++ E P G +I+P GA + ++ + ++FTGS Sbjct: 182 FVLKPASRTPIGALIIGEVLAETDLPKGAFSILPAHRD--GADLFTTDERFKLLSFTGSP 239 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADAD--LDLAVECAHQGVFFNQGQCCTAA 317 VG E ++ K+V LELGG IV AD LD VE G ++ GQ C Sbjct: 240 TVG---WELKKKAGKKKVVLELGGNAAAIVDADQREVLDYVVERLAFGAYYQSGQSCIGV 296 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 R+ VY + + + +GDP D T GP I + + ++ +E+ GA Sbjct: 297 QRIIAHADVYDALREKLIAKTRSLKMGDPKDPATFVGPMISESEARRLAGWMEAAVAAGA 356 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 K+ GG G + T+ V + + ++E FGPV + +F ++ + R N +D+ Sbjct: 357 KIVAGGKV---DGAMFEATLLEGVGRDQDLYRKEAFGPVALLERFSDFDDALARVNDSDF 413 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYA-QAPFGGFKMSGNGRELGEYALAE 496 GL A VFT +L A + LE G V IN + P+GG K SG GRE YA+ + Sbjct: 414 GLQAGVFTDSLSHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIED 473 Query: 497 YTEVKTVTIK 506 TE++ + ++ Sbjct: 474 MTELRLMVVR 483 >4H7N-A nrPDB Length = 474 Score = 183 bits (465), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 133/430 (30%), Positives = 206/430 (47%), Gaps = 18/430 (4%) Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 S W+ L R L Q + R L DTG+ L ++++ + ++ + Sbjct: 42 SRWQELGVEGRITTLQQWKQAILSRREQLTEALVNDTGR--LSITVLEIDSFLASIDRWC 99 Query: 146 GWA-DKIQGKTIPTDDNVVCFTRH-EPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 G A + +Q T + + P + G I+PWNFPL + + PAL G +V+ Sbjct: 100 GLAPELLQTSAKNTSIPFIALQQSLVPYPLVGVISPWNFPLTLSMIDTIPALLAGCAVVV 159 Query: 204 KPAEQTPLTALYLGSLIKEAGFPP---GVVNIVPGFGPTVGAAISSHPQINKIAFTGSTE 260 KP+E P ++ L+ P V+ V G G T GA + ++ ++ + FTGS Sbjct: 160 KPSEIAPR---FVAPLLMALNTVPELRDVLIFVEGGGET-GANLINY--VDFVCFTGSVA 213 Query: 261 VGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRV 320 G+ V E A+R + LELGGK+P IV A+L+LA G N GQ C + R+ Sbjct: 214 TGREVAETAARRFIP-AYLELGGKDPAIVLESANLELATSAILWGAVVNTGQSCLSIERI 272 Query: 321 FVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLE 380 +V E + EF + + A + + P GP I +KQ I + I ++GA + Sbjct: 273 YVAESKFEEFYHQLIAKAHRLQLAYPLVEDGAIGPIIAEKQAGIINDHILDAVEKGAVIH 332 Query: 381 CGGSAME-DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 CGG E G + +PTV + V +M++ EE FGP+ P++ F +EE + AN T YGL Sbjct: 333 CGGKVEELGGGWWCRPTVMTNVNHSMKVMTEETFGPIMPVMPFPDVEEAVYLANDTIYGL 392 Query: 440 TAAVFTKNLDKALKLASALESGTVWIN--CYNALYAQAPFGGFKMSG-NGRELGEYALAE 496 +AAVF + D+ALK+A L +G + IN A+ + F SG G +G L Sbjct: 393 SAAVFAGSEDEALKVARQLNAGAISINDAALTAMMHEGEKNAFNFSGLGGSRVGAAGLKR 452 Query: 497 YTEVKTVTIK 506 + + IK Sbjct: 453 FLRKQAFLIK 462 >6DBB-A nrPDB Length = 511 Score = 176 bits (446), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 133/465 (28%), Positives = 228/465 (49%), Gaps = 28/465 (6%) Query: 67 DKP-DVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKP 125 D P D ++ ++AA AF + WR + A RG L+ +++ +A L L T++ GK Sbjct: 47 DTPADAERKIDAAHDAFLK---WRTVPAPVRGELVRVFGNVLREHKAELGRLVTLEAGK- 102 Query: 126 FLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTD--DNVVCFTRHEPIGVCGAITPWNFP 183 +++ I + G + ++ G TI ++ + + T H PIGVCG I+ +NFP Sbjct: 103 ITSEGLGEVQEMIDICDFAVGLSRQLYGLTIASERPGHRMMETWH-PIGVCGVISAFNFP 161 Query: 184 LLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA-----GFPPGVV-----NIV 233 + + W A A CG+++V KP+E+TPLTA+ L+++A PGV +V Sbjct: 162 VAVWAWNAALAFVCGDSVVWKPSEKTPLTAIACHVLLQKALREFEKTHPGVAPAELGQLV 221 Query: 234 PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA 293 G VG +++ ++ ++ TGS +G+ V + S+ L R LELGG N IV A Sbjct: 222 LGM-RDVGEVLTASKKVPVVSATGSVRMGQEVAKVLSQ-RLARGILELGGNNGMIVAPSA 279 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQ 353 DLDL V GQ CT R+ V + + + R + VG+P + T Sbjct: 280 DLDLVVRAVTFAAVGTAGQRCTTLRRLIVHRSLVEQLLPRIEKAYASVKVGNPLEEGTLV 339 Query: 354 GPQIDQKQFDKILELIESGKKEGAKLECGGSAME---DKGLFIKPTVFSEVTDNMRIAKE 410 GP +D+ FD + + + +++G +++ GG ++ +++P + + + + Sbjct: 340 GPLVDRASFDAMQKALADAREQGGEVK-GGERVDVGHADAYYVRPAIV-RMPKQSAVVER 397 Query: 411 EIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALES--GTVWINC- 467 E F P+ ++ + + ++ I N+ GL++A+FT ++ +A + SA S G V +N Sbjct: 398 ETFAPILYVMVYDNFDDAIDVHNAVPQGLSSAIFTNDMREAEQFMSAAGSDCGIVNVNIG 457 Query: 468 YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP 512 + FGG K +G GRE G A Y T TI + P Sbjct: 458 TSGAEIGGAFGGEKETGGGRESGSDAWKAYMRRATNTINYSRQLP 502 >3JU8-A nrPDB Length = 490 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 133/458 (29%), Positives = 207/458 (45%), Gaps = 14/458 (3%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 +I +W + G+ + +P + + D VD AV AA+ AF W R Sbjct: 9 YIAGQWLAGQ-GETLESLDPVGQGVVWSGRGADATQVDAAVCAAREAF---PAWARRPLE 64 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 R LL + A ++ LA + +TGKP + + + ++ K Sbjct: 65 QRIELLERFAATLKSRADELARVIGEETGKPLWESATEVTSMVNKVAISVQAFRERTGEK 124 Query: 155 TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA- 213 + P D RH+P GV P+NFP + + PAL GN +V KP+E TP A Sbjct: 125 SGPLADATAVL-RHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTPKVAE 183 Query: 214 LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSN 273 L L + I +AG P GV+N+V G G G A+++H ++ + FTGS+ G L+ Sbjct: 184 LTLKAWI-QAGLPAGVLNLVQG-GRETGVALAAHRGLDGLFFTGSSRTGNLLHSQFGGQP 241 Query: 274 LKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE-FVR 332 K + LE+GG NP +V ADLD AV Q F + GQ CT A R+ V + + + + Sbjct: 242 QKILALEMGGNNPLVVEEVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDALLA 301 Query: 333 RSVEYAKKRPVGDPFDVKTE--QGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKG 390 R V + VG FD + G I + +L+ E +GA+ + D Sbjct: 302 RLVAVSATLRVGR-FDEQPAPFMGAVISLSAAEHLLKAQEHLIGKGAQPLLAMTQPIDGA 360 Query: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450 + P + +V+ EE FGP+ ++++ I+ AN+T YGL A + + + ++ Sbjct: 361 ALLTPGIL-DVSAVAERPDEEFFGPLLQVIRYSDFAAAIREANATQYGLAAGLLSDSRER 419 Query: 451 ALKLASALESGTV-WINCYNALYAQAPFGGFKMSGNGR 487 + +G V W + APFGG SGN R Sbjct: 420 FEQFLVESRAGIVNWNKQLTGAASSAPFGGIGASGNHR 457 >5UCD-A nrPDB Length = 457 Score = 162 bits (411), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 126/417 (30%), Positives = 200/417 (47%), Gaps = 20/417 (4%) Query: 96 RGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK-IQGK 154 R + L +L + V ++ L + D GKP ++ + + + D+ + Sbjct: 52 RKQSLERLKEAVINNKEALYSALAEDLGKPKDVVDLAEIGAVLHEIDFALAHLDEWVAPV 111 Query: 155 TIPTDDNVV---CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 ++P+ D + C+ EP GV I P+N+P+ + + L A+ GNT ++KP+E TP Sbjct: 112 SVPSPDIIAPSECYVVQEPYGVTYIIGPFNYPVNLTLTPLIGAIIGGNTCIIKPSETTPE 171 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 T+ + +I EA F P V ++ G G + + S P + I FTGS VGK+V +AA++ Sbjct: 172 TSAVIEKIIAEA-FAPEYVAVIQG-GRDENSHLLSLP-FDFIFFTGSPNVGKVVMQAAAK 228 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 +L V LELGGK P IV DADLD V G F N GQ A ++V V + Sbjct: 229 -HLTPVVLELGGKCPLIVLPDADLDQTVNQLMFGKFINSGQTXIAPDYLYVHYSVKDALL 287 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 R VE K G + ++Q +++ L+E+ +G L + + + L Sbjct: 288 ERLVERVKTE-----LPEINSTGKLVTERQVQRLVSLLEA--TQGQVLVGSQADVSKRAL 340 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTD-YGLTAAVFTKNLDK 450 TV V N + EE+FGP+ P+L+F S+ I + N L VF K++D Sbjct: 341 --SATVVDGVEWNDPLMSEELFGPILPVLEFDSVRTAIDQVNKHHPKPLAVYVFGKDMDV 398 Query: 451 ALKLASALESGTVWIN--CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 A + + ++SG +N +A PFGG SG G G ++ +T K+V I Sbjct: 399 AKGIINQIQSGDAQVNGVMLHAFSPYLPFGGIGASGMGEYHGHFSYLTFTHKKSVRI 455 >3SZA-A nrPDB Length = 469 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 120/442 (27%), Positives = 205/442 (46%), Gaps = 20/442 (4%) Query: 71 VDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAF 130 + +AV+ A+ AF G R R + L L L++ L D K +A+ Sbjct: 20 ISEAVKRARAAFSSG---RTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY 76 Query: 131 FIDLEGCIRTLRYFAG----WADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLM 186 + ++ + + Y WA + P + EP+GV I WN+P + Sbjct: 77 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL 136 Query: 187 LVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISS 246 + + A+ GN +VLKP+E + A L ++I + + ++ G P + Sbjct: 137 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE 195 Query: 247 HPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGV 306 + + I +TGST VGK++ AA++ +L VTLELGGK+PC V + DLD+A G Sbjct: 196 --RFDHILYTGSTGVGKIIMTAAAK-HLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGK 252 Query: 307 FFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKIL 366 F N GQ C A + + + ++ V + ++ + K G+ + G I + F +++ Sbjct: 253 FMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKEFYGEDAKKSRDYGRIISARHFQRVM 311 Query: 367 ELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIE 426 LI EG K+ GG+ + +I PT+ ++V + +EEIFGPV PI+ +S+E Sbjct: 312 GLI-----EGQKVAYGGTG-DAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLE 365 Query: 427 EVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN--CYNALYAQAPFGGFKMSG 484 E I+ N + L +F+ N K+ + SG V N + PFGG SG Sbjct: 366 EAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSG 425 Query: 485 NGRELGEYALAEYTEVKTVTIK 506 G G+ + ++ ++ ++ Sbjct: 426 MGSYHGKKSFETFSHRRSCLVR 447 >1AD3-A nrPDB Length = 452 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 125/443 (28%), Positives = 208/443 (46%), Gaps = 22/443 (4%) Query: 71 VDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAF 130 + V+ A+ AF G R L R + L L ++ + +++ D GK ++ Sbjct: 3 ISDTVKRAREAFNSGKT-RSLQF--RIQQLEALQRMINENLKSISGALASDLGKNEWTSY 59 Query: 131 FID----LEGCIRTLRYFAGWA-DKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLL 185 + + LE T++ WA D+ KT T + + + EP+GV I WN+P Sbjct: 60 YEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDL-YIHSEPLGVVLVIGAWNYPFN 118 Query: 186 MLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAIS 245 + + + A+ GN ++LKP+E + A L +LI + + +V G P + Sbjct: 119 LTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLK 177 Query: 246 SHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQG 305 + + I +TGST VGK+V AA++ +L VTLELGGK+PC V D DLD+A G Sbjct: 178 E--RFDHIMYTGSTAVGKIVMAAAAK-HLTPVTLELGGKSPCYVDKDCDLDVACRRIAWG 234 Query: 306 VFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKI 365 F N GQ C A + + + ++ V + ++ + K G+ + G I+ + F ++ Sbjct: 235 KFMNSGQTCVAPDYILCDPSIQNQIVEK-LKKSLKDFYGEDAKQSRDYGRIINDRHFQRV 293 Query: 366 LELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSI 425 LI++ K G + +I PT+ +V + +EEIFGPV PI+ +S+ Sbjct: 294 KGLIDNQKV------AHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSL 347 Query: 426 EEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN--CYNALYAQAPFGGFKMS 483 EE I+ N + L VF+ N K+ + SG V N + PFGG S Sbjct: 348 EEAIQFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNS 407 Query: 484 GNGRELGEYALAEYTEVKTVTIK 506 G G G+ + ++ ++ +K Sbjct: 408 GMGAYHGKKSFETFSHRRSCLVK 430 >3V9H-A nrPDB Length = 566 Score = 158 bits (399), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 147/531 (27%), Positives = 244/531 (45%), Gaps = 41/531 (7%) Query: 7 AVENGQPDRKPPALPRPIRNLEVKFTKI--FINNE--WHESKSGKKFATCNPSTREQICE 62 A G P+R AL + +++L+ + I + +E W S ++ + ++ + Sbjct: 42 AFTQGSPERD--ALQKALKDLKGRMEAIPCVVGDEEVW---TSDVQYQVSPFNHGHKVAK 96 Query: 63 VEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVER-DRATLAALETMD 121 DK ++KA+EAA A + W R ++ + AD++ RA + A + Sbjct: 97 FCYADKSLLNKAIEAALAARKE---WDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVG 153 Query: 122 TGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK---TIPTDDNVVCFTRHEPIGVCGAIT 178 GK + A I R+ A +A +++G+ ++P N + E G AI+ Sbjct: 154 QGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE--GFVAAIS 211 Query: 179 PWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGP 238 P+NF + APAL GN ++ KP++ L + + +++EAG PP ++ VP GP Sbjct: 212 PFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGP 270 Query: 239 TVGAAISSHPQINKIAFTGSTEVGK-LVKEAASR----SNLKRVTLELGGKNPCIVCADA 293 G ++S + I FTGS K L K+ A R+ E GGKN V A Sbjct: 271 LFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSA 330 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPF-DVKTE 352 D++ V + F GQ C+A +R++V ++ + R +E + VGDP D T Sbjct: 331 DVESVVSGTLRSAFEYGGQKCSACARLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTF 390 Query: 353 QGPQIDQKQFDKILELIESGKKEGA-KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEE 411 ID K F +I + +E + + + GG + G F++P + I KEE Sbjct: 391 FSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEE 450 Query: 412 IFGP-----VQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALE--SGTVW 464 IFGP V P K+K +++ ++T YGLT AVF+++ D + L +G + Sbjct: 451 IFGPVLSVYVYPDDKYKETLQLVD--STTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFY 508 Query: 465 IN--CYNALYAQAPFGGFKMSG-NGRELGEYALAEYTE---VKTVTIKLGD 509 IN ++ Q PFGG + SG N + G + + +T +K LGD Sbjct: 509 INDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGD 559 >4OE4-A nrPDB Length = 580 Score = 156 bits (395), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 147/495 (29%), Positives = 231/495 (46%), Gaps = 56/495 (11%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQI-CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 +I+ NNE F NP+ +Q+ V + + DV + A + A W L Sbjct: 68 RIYDNNE------RALFPQTNPANHQQVLANVTQATEKDV---MNAVKAAKDAKKDWYNL 118 Query: 92 DALSRGRLLHQLADLVE-RDRATLAALETMDTGKPFLHAFFIDLEGCIRTL----RYFAG 146 R + + ADL+ + R + A + GK A ID CI L RY+ Sbjct: 119 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAE-ID---CITELSDFFRYYVK 174 Query: 147 WADKIQGKT-IPTDDNVVCFTRHEPI-GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 +A + + + + D + P+ G A++P+NF + APAL GNT+V K Sbjct: 175 YASDLYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWK 233 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEV--- 261 P++ L+ L ++++EAG P GV+N +PG V + + + FTGST V Sbjct: 234 PSQTAALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKS 293 Query: 262 --GKL---VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTA 316 GK+ V E R + R+ E GGKN +V A++ AV +G F QGQ C+A Sbjct: 294 LYGKIQSGVVEGKYR-DYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSA 352 Query: 317 ASRVFVEEQVYSEF------VRRSVEYAKKRPVGDPF---DVKTEQGPQIDQKQFDKILE 367 ASR+++ E EF + +S P +++ GP I ++ FDK+++ Sbjct: 353 ASRLYLPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVK 412 Query: 368 LIESGKKEGAKLEC--GGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPV-----QPIL 420 +IE KK+ +LE GG + +G F+ PTV + E FGP+ P Sbjct: 413 VIEDAKKD-PELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDT 471 Query: 421 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLAS---ALESGTVWIN--CYNALYAQA 475 +F I ++I N++ Y LT A+F K+ KA++ A +G +IN C A+ +Q Sbjct: 472 EFNEICDIID--NTSQYALTGAIFAKD-RKAIEYADEKLKFSAGNFYINDKCTGAVVSQQ 528 Query: 476 PFGGFKMSGNGRELG 490 FGG +MSG + G Sbjct: 529 WFGGARMSGTDDKAG 543 >4LGZ-A nrPDB Length = 563 Score = 155 bits (393), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 136/467 (29%), Positives = 221/467 (47%), Gaps = 32/467 (6%) Query: 67 DKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM-DTGKP 125 DK +++A++AA A + W R ++ + AD++ R +TM GK Sbjct: 98 DKALLNRAIDAALAARKE---WDLKPMADRAQVFLKAADMLSGPRRAEVLAKTMVGQGKT 154 Query: 126 FLHAFFIDLEGCIRTLRYFAGWADKIQGK---TIPTDDNVVCFTRHEPIGVCGAITPWNF 182 + A I R+ A +A +++G+ ++P N + E G AI+P+NF Sbjct: 155 VIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLE--GFVAAISPFNF 212 Query: 183 PLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGA 242 + APAL GN ++ KP++ L + + +++EAG PP ++ VP GPT G Sbjct: 213 TAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPTFGD 271 Query: 243 AISSHPQINKIAFTGSTEVGKLVKEAASRS-----NLKRVTLELGGKNPCIVCADADLDL 297 ++S + I FTGS K + +++ R+ E GGKN V + AD+D Sbjct: 272 TVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKNFHFVHSSADVDS 331 Query: 298 AVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPF-DVKTEQGPQ 356 V + F GQ C+A SR++V + ++ + R +E + VGDP D T Sbjct: 332 VVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAV 391 Query: 357 IDQKQFDKILELIESGKKEGA-KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGP 415 ID K F +I + +E + + + GG E G +++P + I KEEIFGP Sbjct: 392 IDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDPQEPIMKEEIFGP 451 Query: 416 VQPILKF--KSIEEVIKRANS-TDYGLTAAVFTKNLDKAL-KLASAL---ESGTVWIN-- 466 V + + E +K +S T YGLT AVF + DKA+ + A+ + +G +IN Sbjct: 452 VLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQ--DKAIVQEATRMLRNAAGNFYINDK 509 Query: 467 CYNALYAQAPFGGFKMSG-NGRELGEYALAEYTE---VKTVTIKLGD 509 ++ Q PFGG + SG N + G + + +T +K LGD Sbjct: 510 STGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGD 556 >4QGK-A nrPDB Length = 461 Score = 148 bits (374), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 105/357 (29%), Positives = 173/357 (48%), Gaps = 18/357 (5%) Query: 157 PTDDNVV-----CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 P NV+ + + +P+GV I WN+P ++ + L A+ GN +++KP+E + Sbjct: 84 PVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSEN 143 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 TA L L+ + + I G T + + I +TG+T VGK+V EAA++ Sbjct: 144 TAKILAKLLPQYLDQDLYIVINGGVEETTELL---KQRFDHIFYTGNTAVGKIVMEAAAK 200 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 +L VTLELGGK+PC + D DLD+ G + N GQ C A + E + ++ V Sbjct: 201 -HLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIV 259 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 + E K+ G+ + I+ + F +IL L+ EG K+ GG ++ Sbjct: 260 WKIKETVKEF-YGENIKESPDYERIINLRHFKRILSLL-----EGQKIAFGGET-DEATR 312 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 +I PTV ++V ++ +EEIFGP+ PI+ K+++E I N + L VF+ N Sbjct: 313 YIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAINFINEREKPLALYVFSHNHKLI 372 Query: 452 LKLASALESGTVWIN--CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 ++ SG V N + PFGG SG G G+++ ++ + +K Sbjct: 373 KRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLK 429 >5NNO-A nrPDB Length = 546 Score = 134 bits (336), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 115/362 (31%), Positives = 181/362 (50%), Gaps = 35/362 (9%) Query: 164 CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA 223 C ++EP+GV I WN+PLL+++ L AL GNT V+KP+E P TA L L+ + Sbjct: 111 CELQYEPLGVVLVIGTWNYPLLLILQPLLGALAAGNTAVIKPSELAPATAELLTKLLPKY 170 Query: 224 GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGG 283 VV IV G A + + + I +TGS V ++V AA++ +L VTLELGG Sbjct: 171 -VSSDVVGIVNGGVSETTAVLKE--RFDHILYTGSARVAEIVMAAAAK-HLTPVTLELGG 226 Query: 284 KNPCIV---CADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKK 340 K+P +V CAD ++ + E G N GQ A V VE+ + S V E A+K Sbjct: 227 KSPVVVDDTCAD-NMKVVAERIMWGKIINAGQTSIAPDYVVVEKSMESVLVDALAE-ARK 284 Query: 341 RPVGDPF------DVKTEQGPQ----------IDQKQFDKILELIESGKKEGAKLECGGS 384 +GD F ++ +Q Q ++ F +++E + +G K+ GG Sbjct: 285 AMLGDKFLKVLKGELLVKQKQQFLEESDYPRIVNASHFQRLMEFM-----KGGKVAVGGE 339 Query: 385 AMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 A ++ L I PT+ + + + +EEIFGP+ P+L +++ ++++K NS + L VF Sbjct: 340 A-DEATLTIAPTILTNIDPTHPVMQEEIFGPILPVLTYENEKDILKIINSREKPLALYVF 398 Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQA---PFGGFKMSGNGRELGEYALAEYTEVK 501 + N + S SG V + ++A A PFGG SG G G Y+ ++ + Sbjct: 399 SNNKRFIRGVESRTSSGAV-VVNDVVVHAGADGLPFGGVGRSGMGAYHGRYSFETFSHRR 457 Query: 502 TV 503 V Sbjct: 458 PV 459 >4IDS-A nrPDB Length = 563 Score = 130 bits (328), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 108/350 (30%), Positives = 161/350 (46%), Gaps = 23/350 (6%) Query: 172 GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVN 231 G AITP+NF + APAL GNT++ KP+ L A L++ AG PPGV+N Sbjct: 201 GFVYAITPFNFTSIAGNLPTAPALM-GNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVIN 259 Query: 232 IVPGFGPTVGAAISSHPQINKIAFTGSTEV-GKLVKEAASR----SNLKRVTLELGGKNP 286 +V G G V + P++ I FTGST G L + + + R+ E GGK+ Sbjct: 260 LVTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDF 319 Query: 287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 + A A D+ +G F QGQ C+A SR F+ V+ + A + GD Sbjct: 320 VVAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDI 379 Query: 347 FDVKTEQGPQIDQKQFDKILELIESGKKEGA-KLECGGSAMEDKGLFIKPTVF--SEVTD 403 D+ G IDQ+ F K ++ IE K A + GG + +G F++PTV + TD Sbjct: 380 TDLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTD 439 Query: 404 NMRIAKEEIFGP-----VQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASAL 458 + E FGP V P +++ I +VI + Y LT AV + L L Sbjct: 440 ESFVI--EYFGPLLSVHVYPDERYEQILDVID--TGSRYALTGAVIADDRQAVLTALDRL 495 Query: 459 E--SGTVWIN--CYNALYAQAPFGGFKMSGNGRELGE-YALAEYTEVKTV 503 +G ++N A+ + PFGG + S + G L +T +++ Sbjct: 496 RFAAGNFYVNDKPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSI 545 >2Y53-A nrPDB Length = 534 Score = 85.5 bits (210), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 93/368 (25%), Positives = 157/368 (42%), Gaps = 38/368 (10%) Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 G+ R L R L + L++ R A+ T ++G + +D++G I TL Y+ Sbjct: 57 GAALRALTYAQRAARLADIVKLLQAKRGDYYAIATANSGTT-RNDSAVDIDGGIFTLSYY 115 Query: 145 A--------------GWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWK 190 A G A+ + + +V+ TR GV I +NFP L K Sbjct: 116 AKLGASLGEVHALRDGSAESLSKDRSFSAQHVLSPTR----GVALFINAFNFPSWGLWEK 171 Query: 191 LAPALCCGNTMVLKPAEQTP-LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQ 249 APAL G +++KPA T LT + ++ PPG ++I+ G + I S Sbjct: 172 AAPALLSGVPVIVKPATATAWLTQRMVADVVDAGILPPGALSIICGSSAGLLDQIRS--- 228 Query: 250 INKIAFTGSTEVGKLVK-EAASRSNLKRVTLELGGKNPCIVCADAD-----LDLAVECAH 303 + ++FTGS + ++ A R+ ++ N I+CADA DL ++ Sbjct: 229 FDVVSFTGSADTAATLRAHPAFVQRGARLNVQADSLNSAILCADATPDTPAFDLFIKEVV 288 Query: 304 QGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFD 363 + + GQ CTA R FV E + K VG+P + G + ++Q++ Sbjct: 289 REMTVKSGQKCTAIRRAFVPEAALEPVLEALKAKLAKITVGNPRNDAVRMGSLVSREQYE 348 Query: 364 KILELIESGKKEGAKLECGGSAM------EDKGLFIKPTVF-SEVTDNMRIAKE-EIFGP 415 +L I + ++E A L SA+ + + P +F DN + + E+FGP Sbjct: 349 NVLAGIAALREE-AVLAYDSSAVPLIDADANIAACVAPHLFVVNDPDNATLLHDVEVFGP 407 Query: 416 VQPILKFK 423 V + ++ Sbjct: 408 VASVAPYR 415 >6D97-A nrPDB Length = 547 Score = 65.1 bits (157), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 76/295 (25%), Positives = 135/295 (45%), Gaps = 29/295 (9%) Query: 170 PIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGV 229 P G ITP+NFPL + + +L AL GN VLK + + + L+ + G P Sbjct: 188 PYGPVAIITPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHDCGLPAED 247 Query: 230 VNIVPGFGPTVGA-AISSHPQINKIAFTGSTEVGKLVKEAASRSNLK-RVTLELGGKNPC 287 ++ + G + + ++P++ FTGS+ V + K AA +LK RV LE G + Sbjct: 248 MDFINSDGAVMNKLLLEANPKMT--LFTGSSRVAE--KLAA---DLKGRVKLEDAGFDWK 300 Query: 288 IVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE-FVRRSVEYAKKRPVGD 345 I+ D ++D Q + GQ C+A S +F+ + S + + + +++R + D Sbjct: 301 ILGPDVQEVDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKKLSERRKLED 360 Query: 346 PFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL-----FIKPT-VFS 399 GP + I + K G+K+ GG + + + +KPT VF Sbjct: 361 -----LTIGPVLTVTTEAMIEHMNNLLKIRGSKVLFGGEPLANHSIPKIYGAMKPTAVFV 415 Query: 400 EVTD-----NMRIAKEEIFGPVQPILKFK--SIEEVIKRANSTDYGLTAAVFTKN 447 + + N + +EIFGP Q + ++ +E V++ + LTAA+ + + Sbjct: 416 PLEEILKSGNFELVTKEIFGPFQVVTEYSEDQLELVLEACERMNAHLTAAIVSND 470 >3V4C-A nrPDB Length = 528 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 59/433 (13%) Query: 71 VDKAVEAAQVAF-QRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHA 129 V++A EAA+ AF G R+ R L +AD +E + + + +TG P A Sbjct: 65 VNRACEAAEEAFWTYGYSSRK----ERAAFLRAIADEIEARAEAITEIGSQETGLP--EA 118 Query: 130 FFIDLEGCIRTLRYFAGWADKIQ-GKTIPTDDNVVCFTRH-----------EPIGVCGAI 177 G RT +AD I+ G + + R P+G Sbjct: 119 RLNGERG--RTTGQLRLFADHIEKGDYLDRRVDAAMPERQPAPRQEIRLVQRPVGPVAVF 176 Query: 178 TPWNFPLLMLV--WKLAPALCCGNTMVLKPAEQTP----LTALYLGSLIKEAGFPPGVVN 231 NFPL A AL G +V+K P + A + + I++ G PGV + Sbjct: 177 GASNFPLAFSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIVAEAVDAAIRKTGVHPGVFS 236 Query: 232 IVPGFGPTVGAAISSHPQINKIAFTGSTEVGK-LVKEAASRSNLKRVTLELGGKNPCIVC 290 ++ G VG A+ HP I + FTGS G+ L A+R ELG NP + Sbjct: 237 LIQGGSRDVGHALVQHPHIKAVGFTGSLAGGRALFDLCAARPEPIPFFGELGSVNPMFLL 296 Query: 291 ADADLDLAVECAHQG----VFFNQGQCCTAAS-RVFVEEQVYSEFVRRSVEYAKKRPVGD 345 +A L E QG + GQ CT V +E F +VE K Sbjct: 297 PEA-LKARAETLGQGWAGSLTMGAGQFCTNPGIAVVIEGADADRFTTAAVEALAK----- 350 Query: 346 PFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS--AMEDKGLFIKPTVFSEVTD 403 PQ D I + G+ A A E G P +F E T Sbjct: 351 -------VAPQT--MLTDGIAKAYRDGQARFATRNAVKPLLATESSGRDASPNLF-ETTG 400 Query: 404 NMRIAK----EEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK--NLDKALKLASA 457 +A EE+FGP+ +++ S E+ + A LTA + +L+ A +L Sbjct: 401 AQFLADHALGEEVFGPLGLVVRVGSPAEMEELARGFQGQLTATIHMDAGDLETARRLRPV 460 Query: 458 LE--SGTVWINCY 468 LE +G V +N + Sbjct: 461 LERKAGRVLVNGF 473 >5DBV-A nrPDB Length = 445 Score = 61.6 bits (148), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 84/325 (25%), Positives = 138/325 (42%), Gaps = 40/325 (12%) Query: 170 PIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPP-G 228 P GV GAITP P ++ L GNT+V P T+ + LI EA G Sbjct: 109 PFGVIGAITPCTNPSETIICNTIGMLAGGNTVVFNPHPAAIKTSNFAVQLINEASLSAGG 168 Query: 229 VVNIVPGF-GPTVGAA--ISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKN 285 VNI PT+ ++ + SH I IA TG V V ++ R + G N Sbjct: 169 PVNIACSVRKPTLDSSKIMMSHQDIPLIAATGGPGVVTAVLQSGKRG------IGAGAGN 222 Query: 286 -PCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVG 344 P +V AD+ A E G F+ A V + + +E + Sbjct: 223 PPVLVDETADIRKAAEDIINGCTFDNNLPAIAEKEVVAIDAIANELMN------------ 270 Query: 345 DPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLEC-GGSAMEDKGLF-------IKPT 396 + VK + I ++Q +K+ L+ + K G C G A G+ I+ Sbjct: 271 --YMVKEQGCYAITKEQQEKLTNLVITPK--GLNRNCVGKDARTLLGMIGIDVPSNIRCI 326 Query: 397 VFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG--LTAAVFTKNLDKALKL 454 +F ++ I+ EE+ P+ I++ KS ++ +++A ++G +A + +KN+D+ Sbjct: 327 IFEGEKEHPLIS-EELMMPILGIVRAKSFDDAVEKAVWLEHGNRHSAHIHSKNVDRITTY 385 Query: 455 ASALESGTVWINCYNALYAQAPFGG 479 A A+++ + N + YA FGG Sbjct: 386 AKAIDTAILVKNAPS--YAAIGFGG 408 >5JFN-A nrPDB Length = 524 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 67/320 (20%), Positives = 131/320 (40%), Gaps = 36/320 (11%) Query: 160 DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSL 219 DN + + P GV GAITP P +V L GN++V P + +L L L Sbjct: 177 DNGLTLVEYSPFGVIGAITPTTNPTETIVCNSIGMLAAGNSVVFSPHPRARQVSLLLVRL 236 Query: 220 IKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLK 275 I + G P +V V A+ +HP++ + TG + K V S K Sbjct: 237 INQKLAALGAPENLVVTVEKPSIENTNAMMAHPKVRMLVATGGPAIVKAV-----LSTGK 291 Query: 276 RVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSV 335 + G P +V A+++ A G F+ A + Q+ + Sbjct: 292 KAIGAGAGNPPVVVDETANIEKAACDIVNGCSFDNNLPXVAEKEIIAVAQIADYLI---- 347 Query: 336 EYAKKRPVGDPFDVKTEQGPQI-DQKQFDKILELIESGKKEGAKLECGGSA----MEDKG 390 F++K +I D ++ +L+ + K G + +C G + + G Sbjct: 348 -----------FNLKKNGAYEIKDPAVLQQLQDLVLTAKG-GPQTKCVGKSAVWLLSQIG 395 Query: 391 LFIKPT---VFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG--LTAAVFT 445 + + + + EV +EE+ P+ P+++ +++++ I A ++ TA + + Sbjct: 396 ISVDASIKIILMEVPREHPFVQEELMMPILPLVRVETVDDAIDLAIEVEHDNRHTAIMHS 455 Query: 446 KNLDKALKLASALESGTVWI 465 ++ K K+A +++ T+++ Sbjct: 456 TDVRKLTKMAKLIQT-TIFV 474 >5UJU-A nrPDB Length = 576 Score = 54.7 bits (130), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 67/277 (24%), Positives = 117/277 (42%), Gaps = 31/277 (11%) Query: 195 LCCGNTMVLKPAEQTPL----TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISS---H 247 L GNT+++KP L T +++EAGF P VV ++ P GA + Sbjct: 229 LATGNTVIVKPHPGAILPLAITVRIARDVLREAGFDPNVVTLL-ATEPNDGALVQDLALR 287 Query: 248 PQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVF 307 P+I I FTGST+ G ++ A ++ +V E G N ++ + DL A + + Sbjct: 288 PEIKLIDFTGSTQNGTWLERHAHQA---QVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLA 344 Query: 308 FNQGQCCTAASRVFV--------EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQ 359 GQ CTA ++V + + V +++ A ++ GDP I Sbjct: 345 LYSGQMCTAPQNIYVPRDGIRTADGHASFDEVAQAIAGAVQKLTGDP----ARSVELIGA 400 Query: 360 KQFDKILELIESGKKEGAKL----ECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGP 415 Q D + I++ + G L A D + + +V D + +E FGP Sbjct: 401 IQNDGVTARIDAARAVGRVLLDSQTLQHPAFPDARVRTPLVLQLDVADREKF-TQEWFGP 459 Query: 416 VQPILKFKSIEEVIKRAN--STDYG-LTAAVFTKNLD 449 + ++ S + + A + ++G LT +V++ D Sbjct: 460 ISFVIATDSTAQSLDLAGEIAAEHGALTLSVYSTADD 496 >1EZ0-A nrPDB Length = 510 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 96/398 (24%), Positives = 150/398 (37%), Gaps = 64/398 (16%) Query: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI-RTLRYFAG 146 +RRL+ R LL +A +E + A ++T P + L G I RT Sbjct: 46 FRRLNNSKRASLLRTIASELEARSDDIIARAHLETALPE-----VRLTGEIARTANQLRL 100 Query: 147 WADKIQGKT---------------IPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVW-- 189 +AD + + +P D P+ V GA NFPL Sbjct: 101 FADVVNSGSYHQAILDTPNPTRAPLPKPDIRRQQIALGPVAVFGA---SNFPLAFSAAGG 157 Query: 190 KLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA----GFPPGVVNIVPGFGPTVGAAIS 245 A AL G +++K P T+ + I++A P + ++ G +G A+ Sbjct: 158 DTASALAAGCPVIVKGHTAHPGTSQIVAECIEQALKQEQLPQAIFTLLQGNQRALGQALV 217 Query: 246 SHPQINKIAFTGSTEVGK-LVKEAASRSNLKRVTLELGGKNPCIVC-----ADADL-DLA 298 SHP+I + FTGS G+ L A R ELG NP + A ADL D Sbjct: 218 SHPEIKAVGFTGSVGGGRALFNLAHERPEPIPFYGELGAINPTFIFPSAMRAKADLADQF 277 Query: 299 VECAHQGVFFNQGQCCTAASRVFV----EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQG 354 V G GQ CT VF E Q + E + + + P ++ Sbjct: 278 VASMTMGC----GQFCTKPGVVFALNTPETQAFIETAQSLIRQQSPSTLLTP-GIRDSYQ 332 Query: 355 PQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIA---KEE 411 Q+ + D +++ S A+ C SA+ F ++N R +EE Sbjct: 333 SQVVSRGSDDGIDVTFS----QAESPCVASAL-----------FVTSSENWRKHPAWEEE 377 Query: 412 IFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 IFGP I+ +++ +++ + LTA + D Sbjct: 378 IFGPQSLIVVCENVADMLSLSEMLAGSLTATIHATEED 415 >3MY7-A nrPDB Length = 452 Score = 48.1 bits (113), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 46/180 (25%), Positives = 73/180 (40%), Gaps = 11/180 (6%) Query: 159 DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGS 218 DDN+ T EP+G+ I P P ++K +L N ++ P + + Sbjct: 92 DDNLGTMTIAEPVGIICGIVPTTNPTSTAIFKSLISLKTRNGIIFSPHPRAKNSTNDAAK 151 Query: 219 LIKEAGFPPGVVNIVPGF--GPTV--GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNL 274 L+ +A G + G+ P+V A+ H I I TG +VK A S Sbjct: 152 LVLDAAVAAGAPKDIIGWIDQPSVELSNALMKHDDIALILATGGP---GMVKAAYSSG-- 206 Query: 275 KRVTLELGGKN-PCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRR 333 + + +G N P ++ AD+ AV F+ G C + V V ++VY E R Sbjct: 207 -KPAIGVGAGNVPVVIDETADIKRAVASVLMSKTFDNGVVCASEQAVIVVDEVYDEVKER 265 >3K9D-A nrPDB Length = 464 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 44/181 (24%), Positives = 72/181 (39%), Gaps = 23/181 (12%) Query: 170 PIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKE----AGF 225 P+GV + P P +++K ++ GN++V P L +I E AG Sbjct: 108 PLGVVAGLIPSTNPTSTVIYKTLISIKAGNSIVFSPHPNALKAILETVRIISEAAEKAGC 167 Query: 226 PPGVVNIVPGFGPTVGAA--ISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELG- 282 P G ++ + PT+ + H I TG + +VK A S T +G Sbjct: 168 PKGAISCMT--VPTIQGTDQLMKHKDTAVILATGGS---AMVKAAYSSG-----TPAIGV 217 Query: 283 --GKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE----EQVYSEFVRRSVE 336 G P + A++ AV+ F+ G C + V VE E V +EF ++ Sbjct: 218 GPGNGPAFIERSANIPRAVKHILDSKTFDNGTICASEQSVVVERVNKEAVIAEFRKQGAH 277 Query: 337 Y 337 + Sbjct: 278 F 278 >2DQ3-A nrPDB Length = 425 Score = 35.8 bits (81), Expect = 0.052, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 15/87 (17%) Query: 196 CCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVP-------GFGPTVGAAISSHP 248 C + + L P + PLT LY ++KE P + P +G + I H Sbjct: 221 CERDNLYLIPTAEVPLTNLYREEILKEENLPIYLTAYTPCYRREAGAYGKDIRGIIRQH- 279 Query: 249 QINKIAF-------TGSTEVGKLVKEA 268 Q +K+ T E+ KLVK+A Sbjct: 280 QFDKVELVKIVHPDTSYDELEKLVKDA 306 >4GHK-A nrPDB Length = 444 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/59 (25%), Positives = 28/59 (47%) Query: 409 KEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC 467 + E PV I I+ I+ N T A+ T++ D+A++ ++S +V +N Sbjct: 337 RTEYLAPVLAIKIVDGIDAAIEHINEYGSHHTDAIVTEDHDRAMRFLREVDSASVMVNA 395 >1O20-A nrPDB Length = 427 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 13/56 (23%), Positives = 26/56 (46%) Query: 423 KSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFG 478 K+++E I+ G + ++ T+N A K S +++ V++N FG Sbjct: 334 KNVDEAIEHIKKYSTGHSESILTENYSNAKKFVSEIDAAAVYVNASTRFTDGGQFG 389 >5Z0Q-C nrPDB Length = 389 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 23/42 (54%), Gaps = 3/42 (7%) Query: 53 NPSTREQICEVEEGDKPDVD-KAVEAAQVAFQRGSPWRRLDA 93 NP R + + +G PDVD A AA A++ G PW LDA Sbjct: 256 NPELRARFNRMRKGMVPDVDVLAYVAASAAWREGQPW--LDA 295 >2HZK-A nrPDB Length = 365 Score = 29.6 bits (65), Expect = 3.4, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 245 SSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQ 304 SS P+ F G+ + K++ EA + N + G P + ADA + VEC H Sbjct: 38 SSFPKSLDTIFGGAEVLSKMLSEA-TDGNFQIQVFSAGELVPGLQAADAVTEGTVECCHT 96 Query: 305 GVFFNQGQCCTAA 317 ++ G+ T A Sbjct: 97 VGYYYWGKDPTFA 109 >2ACV-A nrPDB Length = 463 Score = 29.3 bits (64), Expect = 4.8, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 22/42 (52%) Query: 343 VGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS 384 VG D+K + P++DQ Q D IL+ ++ + C GS Sbjct: 244 VGPLLDLKGQPNPKLDQAQHDLILKWLDEQPDKSVVFLCFGS 285 >5ZCY-A nrPDB Length = 99 Score = 28.9 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 4/29 (13%) Query: 357 IDQKQFDKILELIESGKKEGAKLECGGSA 385 ID+K+FD L E KK AKL CGG+A Sbjct: 43 IDEKEFD----LEEIAKKLKAKLACGGTA 67 >5Y9F-A nrPDB Length = 500 Score = 28.5 bits (62), Expect = 7.5, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 3/55 (5%) Query: 235 GFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIV 289 G G +G +S HP NK+ T ++ V V +R N V+++ CI+ Sbjct: 100 GRGQPLGVGLSGHPLYNKLDDTENSHVASAVDTKDTRDN---VSVDYKQTQLCII 151 >3AFG-A nrPDB Length = 539 Score = 28.5 bits (62), Expect = 8.3, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 6/29 (20%) Query: 133 DLEGCIRTLRYFAGWADKIQGKTIPTDDN 161 DL+G + GW D + GKT P DDN Sbjct: 156 DLQGKV------IGWVDFVNGKTTPYDDN 178 >3FCR-A nrPDB Length = 458 Score = 28.1 bits (61), Expect = 8.8, Method: Compositional matrix adjust. Identities = 37/159 (23%), Positives = 60/159 (37%), Gaps = 34/159 (21%) Query: 224 GFPPGVVNIVPG----FGPTVGAAISSHPQINKIAFTGSTEVGKL----------VKEAA 269 G P ++ I G + P G+ +S ++ K+ G+ E G + + AA Sbjct: 279 GLEPDIITIAKGLTSAYAPLSGSIVSD--KVWKVLEQGTDENGPIGHGWTYSAHPIGAAA 336 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 +NLK + +L+L G + N + V + V E Sbjct: 337 GVANLKLLD---------------ELNLVSNAGEVGAYLNATMAEALSQHANVGD-VRGE 380 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQF--DKIL 366 + +VE+ K R FD + GPQI K DKI+ Sbjct: 381 GLLCAVEFVKDRDSRTFFDAADKIGPQISAKLLEQDKII 419 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5FHZ-A nrPDB 770 0.0 5AC2-A nrPDB 729 0.0 5AC0-A nrPDB 728 0.0 4X2Q-A nrPDB 709 0.0 1O9J-A nrPDB 699 0.0 5L13-A nrPDB 696 0.0 1AG8-A nrPDB 691 0.0 5GT6-A nrPDB 632 0.0 4PXL-B nrPDB 626 e-179 4V3F-A nrPDB 618 e-177 4PZ2-A nrPDB 617 e-177 4CAZ-A nrPDB 611 e-175 4O6R-A nrPDB 609 e-174 3RHO-A nrPDB 595 e-170 3IWK-A nrPDB 590 e-169 3IWJ-A nrPDB 583 e-167 4GO4-A nrPDB 582 e-166 4MPY-A nrPDB 581 e-166 3JZ4-A nrPDB 578 e-165 4O5H-A nrPDB 572 e-163 4I8P-A nrPDB 570 e-163 6B4R-B nrPDB 570 e-163 6QAO-A nrPDB 570 e-163 4QYJ-A nrPDB 569 e-163 1BPW-A nrPDB 569 e-162 4I8Q-A nrPDB 568 e-162 5IUV-A nrPDB 566 e-162 2D4E-A nrPDB 563 e-161 3R31-A nrPDB 555 e-158 4V6H-A nrPDB 546 e-155 5KLK-A nrPDB 540 e-154 5J77-A nrPDB 539 e-153 3TY7-A nrPDB 534 e-152 1WNB-A nrPDB 533 e-152 6C43-A nrPDB 529 e-151 3EK1-A nrPDB 528 e-150 4U3W-A nrPDB 522 e-148 4LIH-A nrPDB 521 e-148 3U4J-A nrPDB 520 e-148 2HG2-A nrPDB 520 e-148 3I44-A nrPDB 519 e-148 3K2W-A nrPDB 517 e-147 4F3X-A nrPDB 517 e-147 3QAN-A nrPDB 512 e-145 3B4W-A nrPDB 505 e-143 3RJL-A nrPDB 505 e-143 5EUY-A nrPDB 505 e-143 1T90-A nrPDB 503 e-143 5X5U-A nrPDB 501 e-142 3RHD-A nrPDB 498 e-141 2JG7-A nrPDB 498 e-141 5VBF-A nrPDB 492 e-139 4JZ6-A nrPDB 491 e-139 3RH9-A nrPDB 489 e-139 4YWE-A nrPDB 488 e-138 4X0T-A nrPDB 488 e-138 2W8P-A nrPDB 486 e-137 4DNG-A nrPDB 480 e-136 4PXN-A nrPDB 476 e-135 5UR2-A nrPDB 476 e-134 5TJR-A nrPDB 475 e-134 2J5N-A nrPDB 473 e-134 3PRL-A nrPDB 473 e-133 2QE0-A nrPDB 471 e-133 3R64-A nrPDB 468 e-132 4ZZ7-A nrPDB 467 e-132 6MVR-A nrPDB 466 e-131 6FK3-A nrPDB 465 e-131 3EFV-A nrPDB 460 e-130 4OGD-A nrPDB 458 e-129 3ROS-A nrPDB 455 e-128 3VZ3-A nrPDB 455 e-128 3VZ0-A nrPDB 454 e-128 5N5S-A nrPDB 445 e-125 5KF0-A nrPDB 444 e-125 5JRY-A nrPDB 438 e-123 5U0M-A nrPDB 433 e-122 5J6B-A nrPDB 427 e-120 4E4G-A nrPDB 426 e-119 1UXV-A nrPDB 421 e-118 3SZA-A nrPDB 419 e-117 3V9H-A nrPDB 416 e-117 6DBB-A nrPDB 415 e-116 4LGZ-A nrPDB 411 e-115 4KNA-A nrPDB 409 e-114 3JU8-A nrPDB 405 e-113 1AD3-A nrPDB 403 e-112 4I3V-A nrPDB 396 e-110 4QGK-A nrPDB 381 e-106 4H7N-A nrPDB 365 e-101 4OE4-A nrPDB 365 e-101 5UCD-A nrPDB 358 3e-99 4IDS-A nrPDB 332 3e-91 5NNO-A nrPDB 314 7e-86 2Y53-A nrPDB 252 3e-67 3V4C-A nrPDB 240 1e-63 6D97-A nrPDB 222 3e-58 5DBV-A nrPDB 222 4e-58 1EZ0-A nrPDB 200 1e-51 5JFN-A nrPDB 198 3e-51 5UJU-A nrPDB 169 2e-42 3MY7-A nrPDB 168 5e-42 Sequences not found previously or not previously below threshold: 5J7I-A nrPDB 146 2e-35 3K9D-A nrPDB 139 4e-33 1O20-A nrPDB 117 1e-26 4GHK-A nrPDB 100 3e-21 1VLU-A nrPDB 83 4e-16 4JBE-A nrPDB 77 2e-14 2H5G-A nrPDB 73 3e-13 4Q1V-A nrPDB 33 0.27 4U83-A nrPDB 33 0.40 4XFE-A nrPDB 33 0.50 3AGK-A nrPDB 32 0.56 6AHD-9 nrPDB 32 0.73 3Q09-A nrPDB 31 1.1 4G9Q-A nrPDB 31 1.3 4N4Q-A nrPDB 31 1.4 5Z0Q-C nrPDB 31 1.4 3HOA-A nrPDB 31 1.7 3DOD-A nrPDB 30 2.7 3LOO-A nrPDB 30 3.1 4WJB-A nrPDB 29 3.4 3UF0-A nrPDB 29 3.4 3HSK-A nrPDB 29 3.6 1J3N-A nrPDB 29 3.9 2WMI-B nrPDB 29 5.0 2IPH-A nrPDB 29 5.3 4WHB-E nrPDB 29 5.7 3ZQJ-A nrPDB 29 6.1 1R6V-A nrPDB 29 6.5 1O54-A nrPDB 29 6.9 2MBB-A nrPDB 28 7.4 1V9N-A nrPDB 28 7.7 5E7H-A nrPDB 28 8.5 4YJI-A nrPDB 28 8.8 5E7G-A nrPDB 28 9.1 3C3E-A nrPDB 28 9.3 3UPY-A nrPDB 28 9.4 >5FHZ-A nrPDB Length = 529 Score = 770 bits (1990), Expect = 0.0, Method: Composition-based stats. Identities = 512/512 (100%), Positives = 512/512 (100%) Query: 1 MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI 60 MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI Sbjct: 18 MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI 77 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 120 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM Sbjct: 78 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 137 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW 180 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW Sbjct: 138 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW 197 Query: 181 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV 240 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV Sbjct: 198 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTV 257 Query: 241 GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE 300 GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE Sbjct: 258 GAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVE 317 Query: 301 CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK 360 CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK Sbjct: 318 CAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQK 377 Query: 361 QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL 420 QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL Sbjct: 378 QFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPIL 437 Query: 421 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF 480 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF Sbjct: 438 KFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGF 497 Query: 481 KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP 512 KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP Sbjct: 498 KMSGNGRELGEYALAEYTEVKTVTIKLGDKNP 529 >5AC2-A nrPDB Length = 501 Score = 729 bits (1882), Expect = 0.0, Method: Composition-based stats. Identities = 350/494 (70%), Positives = 419/494 (84%) Query: 18 PALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEA 77 P LP + +L++++TKIFINNEWH+S SGKKF NP+T E++C+VEEGDK DVDKAV+A Sbjct: 7 PDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKA 66 Query: 78 AQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGC 137 A+ AFQ GSPWR +DA RGRLL++LADL+ERDR LA +E+M+ GK + +A+ DL GC Sbjct: 67 ARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGC 126 Query: 138 IRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCC 197 I+TLRY AGWADKIQG+TIP D N +TRHEPIGVCG I PWNFPL+ML+WK+ PAL C Sbjct: 127 IKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSC 186 Query: 198 GNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTG 257 GNT+V+KPAEQTPLTAL++ SLIKEAGFPPGVVNIVPG+GPT GAAISSH I+K+AFTG Sbjct: 187 GNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTG 246 Query: 258 STEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAA 317 STEVGKL+KEAA +SNLKRVTLELGGK+PCIV ADADLD AVE AH GVF++QGQCC AA Sbjct: 247 STEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAA 306 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 SR+FVEE +Y EFVRRSVE AKK +G+P QGPQID++Q+DKIL+LIESGKKEGA Sbjct: 307 SRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGA 366 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 KLECGG +KG F++PTVFS VTD MRIAKEEIFGPVQ I+KFKS+++VIKRAN+T Y Sbjct: 367 KLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFY 426 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL+A VFTK++DKA+ ++SAL++GTVW+NCY + AQ PFGGFKMSGNGRELGEY EY Sbjct: 427 GLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEY 486 Query: 498 TEVKTVTIKLGDKN 511 TEVKTVT+K+ KN Sbjct: 487 TEVKTVTVKISQKN 500 >5AC0-A nrPDB Length = 501 Score = 728 bits (1881), Expect = 0.0, Method: Composition-based stats. Identities = 352/496 (70%), Positives = 420/496 (84%) Query: 16 KPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAV 75 P +P P+ NL+ K+TKIFINNEWH S SGKKF NP+T E++CEVEEGDK DVDKAV Sbjct: 5 AMPDVPAPLTNLQFKYTKIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAV 64 Query: 76 EAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLE 135 +AA+ AFQ GSPWR +DA RGRLL++LADL+ERDR LA +E M+ GK F +A+ +DL Sbjct: 65 KAARQAFQIGSPWRTMDASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLG 124 Query: 136 GCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPAL 195 GCI+TLRY AGWADKIQG+TIP D N +TR EP+GVCG I PWNFPLLM +WK+ PAL Sbjct: 125 GCIKTLRYCAGWADKIQGRTIPMDGNFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPAL 184 Query: 196 CCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAF 255 CGNT+V+KPAEQTPLTAL++GSLIKEAGFPPGVVNIVPG+GPT GAAISSH ++K+AF Sbjct: 185 SCGNTVVVKPAEQTPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAF 244 Query: 256 TGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCT 315 TGSTEVGKL+KEAA +SNLKRV+LELGGK+PCIV ADADLD AVE AHQGVF++QGQCC Sbjct: 245 TGSTEVGKLIKEAAGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCI 304 Query: 316 AASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE 375 AASR+FVEE +Y EFVRRSVE AKK +G+P QGPQID++Q++KIL+LIESGKKE Sbjct: 305 AASRLFVEESIYDEFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKE 364 Query: 376 GAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 GAKLECGG +KG FI+PTVFS+VTD+MRIAKEEIFGPVQ I+KFKS+++VIKRAN+T Sbjct: 365 GAKLECGGGPWGNKGYFIQPTVFSDVTDDMRIAKEEIFGPVQQIMKFKSLDDVIKRANNT 424 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL+A +FT ++DKA+ ++SAL+SGTVW+NCY+ + AQ PFGGFKMSGNGRELGEY Sbjct: 425 FYGLSAGIFTNDIDKAITVSSALQSGTVWVNCYSVVSAQCPFGGFKMSGNGRELGEYGFH 484 Query: 496 EYTEVKTVTIKLGDKN 511 EYTEVKTVTIK+ KN Sbjct: 485 EYTEVKTVTIKISQKN 500 >4X2Q-A nrPDB Length = 504 Score = 709 bits (1830), Expect = 0.0, Method: Composition-based stats. Identities = 353/491 (71%), Positives = 423/491 (86%) Query: 21 PRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQV 80 P P NLE+K+TKIFINNEW S+SG+ F NP+T EQ+CEV+E DK D+DKAV+AA++ Sbjct: 13 PSPTPNLEIKYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQEADKADIDKAVQAARL 72 Query: 81 AFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT 140 AF GS WRR+DA RGRLL +LADLVERDRA LA +E+++ GKPFL AF++DL+G I+T Sbjct: 73 AFSLGSVWRRMDASERGRLLDKLADLVERDRAVLATMESLNGGKPFLQAFYVDLQGVIKT 132 Query: 141 LRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT 200 RY+AGWADKI G TIP D + FTRHEPIGVCG I PWNFPLLM WK+APALCCGNT Sbjct: 133 FRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFAWKIAPALCCGNT 192 Query: 201 MVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTE 260 +V+KPAEQTPL+ALY+G+LIKEAGFPPGV+NI+PG+GPT GAAI+SH I+KIAFTGSTE Sbjct: 193 VVIKPAEQTPLSALYMGALIKEAGFPPGVINILPGYGPTAGAAIASHIGIDKIAFTGSTE 252 Query: 261 VGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRV 320 VGKL++EAA RSNLKRVTLELGGK+P I+ ADADLD AVE AHQGVFFNQGQCCTA SR+ Sbjct: 253 VGKLIQEAAGRSNLKRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQCCTAGSRI 312 Query: 321 FVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLE 380 FVEE +Y EFVRRSVE AK+R VG PFD TEQGPQID+KQ++KILELI+SG EGAKLE Sbjct: 313 FVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKLE 372 Query: 381 CGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLT 440 CGG + KG FI+PTVFS VTD+MRIAKEEIFGPVQ IL+FK+++EVI+RAN++D+GL Sbjct: 373 CGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRFKTMDEVIERANNSDFGLV 432 Query: 441 AAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEV 500 AAVFT +++KAL ++SA+++GTVWINCYNAL AQ+PFGGFKMSGNGRE+GE+ L EY+EV Sbjct: 433 AAVFTNDINKALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSGNGREMGEFGLREYSEV 492 Query: 501 KTVTIKLGDKN 511 KTVT+K+ KN Sbjct: 493 KTVTVKIPQKN 503 >1O9J-A nrPDB Length = 501 Score = 699 bits (1805), Expect = 0.0, Method: Composition-based stats. Identities = 337/494 (68%), Positives = 410/494 (82%) Query: 18 PALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEA 77 P LP P+ N++++ TK+FINNEWHES SGK F NP+T E+ICEVEE DK DVDKAV+A Sbjct: 7 PDLPAPLTNIKIQHTKLFINNEWHESVSGKTFPVFNPATEEKICEVEEADKEDVDKAVKA 66 Query: 78 AQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGC 137 A+ AFQ GSPWR +DA RG+L+++LADL+ERDR LA LE+++ GK F A+ +DL+ C Sbjct: 67 AREAFQMGSPWRTMDASERGQLIYKLADLIERDRLLLATLESINAGKVFASAYLMDLDYC 126 Query: 138 IRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCC 197 I+ LRY AGWADKIQG+TIP D +TRHEPIGVCG I PWN P+++L K+ PALCC Sbjct: 127 IKALRYCAGWADKIQGRTIPVDGEFFSYTRHEPIGVCGLIFPWNAPMILLACKIGPALCC 186 Query: 198 GNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTG 257 GNT+++KPAEQTPLTAL++ SLIKEAGFPPGVVNIVPG+GPT GAAISSH ++K+AFTG Sbjct: 187 GNTVIVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTG 246 Query: 258 STEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAA 317 STEVGK+++EAA++SNLKRVTLELG KNPCIV ADADLD AVE AHQGVF NQGQ C AA Sbjct: 247 STEVGKMIQEAAAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAA 306 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 S++FVEE +Y EFV+RSVE AKK G+P GPQI++ Q +KI+ELIESGKKEGA Sbjct: 307 SKLFVEEAIYDEFVQRSVERAKKYVFGNPLTPGVNHGPQINKAQHNKIMELIESGKKEGA 366 Query: 378 KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 KLECGG +KG FI+PTVFS VTD+MRIAKEEIFGPVQ I+KFKS++EVIKRAN+T Y Sbjct: 367 KLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFKSLDEVIKRANNTYY 426 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL A VFTK+LDKA+ ++SAL++GTVW+NCY A AQ+P GGFKMSG+GRE+GEY + EY Sbjct: 427 GLVAGVFTKDLDKAVTVSSALQAGTVWVNCYLAASAQSPAGGFKMSGHGREMGEYGIHEY 486 Query: 498 TEVKTVTIKLGDKN 511 TEVKTVT+K+ +KN Sbjct: 487 TEVKTVTMKISEKN 500 >5L13-A nrPDB Length = 517 Score = 696 bits (1797), Expect = 0.0, Method: Composition-based stats. Identities = 326/496 (65%), Positives = 394/496 (79%) Query: 16 KPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAV 75 A+P P + EV +IFINNEWH++ S K F T NPST E IC+V EGDK DVDKAV Sbjct: 21 ATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPSTGEVICQVAEGDKEDVDKAV 80 Query: 76 EAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLE 135 +AA+ AFQ GSPWRR+DA RGRLL++LADL+ERDR LAALET+D GKP++ ++ +DL+ Sbjct: 81 KAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLAALETLDNGKPYVISYLVDLD 140 Query: 136 GCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPAL 195 ++ LRY+AGWADK GKTIP D + +TRHEP+GVCG I PWNFPLLM WKL PAL Sbjct: 141 MVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPAL 200 Query: 196 CCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAF 255 GN +V+K AEQTPLTALY+ +LIKEAGFPPGVVNIVPGFGPT GAAI+SH ++K+AF Sbjct: 201 ATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAF 260 Query: 256 TGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCT 315 TGSTE+G++++ AA SNLKRVTLELGGK+P I+ +DAD+D AVE AH +FFNQGQCC Sbjct: 261 TGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCC 320 Query: 316 AASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE 375 A SR FV+E +Y EFV RSV AK R VG+PFD KTEQGPQ+D+ QF KIL I +GK+E Sbjct: 321 AGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQE 380 Query: 376 GAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 GAKL CGG D+G FI+PTVF +V D M IAKEEIFGPV ILKFK+IEEV+ RAN++ Sbjct: 381 GAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNS 440 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL AAVFTK+LDKA L+ AL++GTVW+NCY+ AQ+PFGG+KMSG+GRELGEY L Sbjct: 441 TYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQ 500 Query: 496 EYTEVKTVTIKLGDKN 511 YTEVKTVT+K+ KN Sbjct: 501 AYTEVKTVTVKVPQKN 516 >1AG8-A nrPDB Length = 499 Score = 691 bits (1785), Expect = 0.0, Method: Composition-based stats. Identities = 319/496 (64%), Positives = 396/496 (79%) Query: 16 KPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAV 75 A+P P + EV + +IFINNEWH++ S K F T NPST + IC V EGDK DVD+AV Sbjct: 3 ATQAVPTPNQQPEVLYNQIFINNEWHDAVSKKTFPTVNPSTGDVICHVAEGDKADVDRAV 62 Query: 76 EAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLE 135 +AA+ AFQ GSPWRR+DA RGRLL++LADL+ERDR LAALET+D GKP++ ++ +DL+ Sbjct: 63 KAARAAFQLGSPWRRMDASERGRLLNRLADLIERDRTYLAALETLDNGKPYIISYLVDLD 122 Query: 136 GCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPAL 195 ++ LRY+AGWADK GKTIP D + +TRHEP+GVCG I PWNFPLLM WKL PAL Sbjct: 123 MVLKCLRYYAGWADKYHGKTIPIDGDYFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPAL 182 Query: 196 CCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAF 255 GN +V+K AEQTPLTALY+ +LIKEAGFPPGVVN++PGFGPT GAAI+SH ++K+AF Sbjct: 183 ATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNVIPGFGPTAGAAIASHEDVDKVAF 242 Query: 256 TGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCT 315 TGSTEVG L++ AA +SNLKRVTLE+GGK+P I+ +DAD+D AVE AH +FFNQGQCC Sbjct: 243 TGSTEVGHLIQVAAGKSNLKRVTLEIGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCC 302 Query: 316 AASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE 375 A SR FV+E +Y+EFV RSV AK R VG+PFD +TEQGPQ+D+ QF K+L I+SGK+E Sbjct: 303 AGSRTFVQEDIYAEFVERSVARAKSRVVGNPFDSRTEQGPQVDETQFKKVLGYIKSGKEE 362 Query: 376 GAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 G KL CGG A D+G FI+PTVF ++ D M IAKEEIFGPV ILKFKS+EEV+ RAN++ Sbjct: 363 GLKLLCGGGAAADRGYFIQPTVFGDLQDGMTIAKEEIFGPVMQILKFKSMEEVVGRANNS 422 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL AAVFTK+LDKA L+ AL++GTVW+NCY+ AQ+PFGG+K+SG+GRELGEY L Sbjct: 423 KYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKLSGSGRELGEYGLQ 482 Query: 496 EYTEVKTVTIKLGDKN 511 YTEVKTVT+++ KN Sbjct: 483 AYTEVKTVTVRVPQKN 498 >5GT6-A nrPDB Length = 508 Score = 632 bits (1630), Expect = 0.0, Method: Composition-based stats. Identities = 242/475 (50%), Positives = 318/475 (66%), Gaps = 2/475 (0%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K+FIN E+ + GK F T NP+T + + V E + D+D AV+AA+ AF+ G PW + Sbjct: 35 KMFINGEFVSAIGGKTFETYNPATEDVLAVVCEAQEEDIDAAVKAARSAFESG-PWAEMT 93 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R L+++LADL+E R LA LE +D GKP+ A D+ + RY+AGW KI Sbjct: 94 TAERAHLIYKLADLIEEHREELAQLEALDNGKPYQVALDDDISATVENYRYYAGWTTKII 153 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 G+TIP + + +TRHEP+GV G I PWNFPL+M WK+ AL G T+VLKPAEQTPL+ Sbjct: 154 GQTIPISKDYLNYTRHEPVGVVGQIIPWNFPLVMSSWKMGAALATGCTIVLKPAEQTPLS 213 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 LY L KEAGFP GVVN VPGFGP GAAI +H I+K+AFTGST GK + ++ Sbjct: 214 LLYAAKLFKEAGFPNGVVNFVPGFGPEAGAAIVNHHDIDKVAFTGSTVTGKYIMRQSAEM 273 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 +K VTLELGGK+P I+ DADL+ A+ A QG+ +N GQ C+A SRVFV + Y V Sbjct: 274 -IKHVTLELGGKSPNIILEDADLEEAINGAFQGIMYNHGQNCSAGSRVFVHRKHYETVVD 332 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLF 392 V+ A +G + +TE GP + +KQ +++L IE GKKEGA + GG +KG F Sbjct: 333 ALVKMANNVKLGAGMEKETEMGPLVSKKQQERVLNYIEQGKKEGATVAAGGERALEKGYF 392 Query: 393 IKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKAL 452 +KPTVF++VTD+M I KEEIFGPV +L F S EEVI+RAN++ YGL A V+T+N+ Sbjct: 393 VKPTVFTDVTDDMTIVKEEIFGPVVVVLPFDSTEEVIERANNSSYGLAAGVWTQNIKTGH 452 Query: 453 KLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 ++A+ L++GTVWIN YN A APFGG+K SG GRELG YAL YTEVK+V + + Sbjct: 453 QVANKLKAGTVWINDYNLENAAAPFGGYKQSGIGRELGSYALDNYTEVKSVWVNI 507 >4PXL-B nrPDB Length = 517 Score = 626 bits (1614), Expect = e-179, Method: Composition-based stats. Identities = 247/506 (48%), Positives = 347/506 (68%), Gaps = 11/506 (2%) Query: 2 ATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQIC 61 ATANG+ G + + +EV+FTK+FI+ ++ ++ SGK F T +P T E I Sbjct: 17 ATANGS-SKGSFE---------VPKVEVRFTKLFIDGKFVDAVSGKTFETRDPRTGEVIA 66 Query: 62 EVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMD 121 + EGDK DVD AV+AA+ AF G PW R+ RGR+LH+ ADL++ LAAL+T+D Sbjct: 67 SIAEGDKADVDLAVKAAREAFDNG-PWPRMTGYERGRILHRFADLIDEHVEELAALDTVD 125 Query: 122 TGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWN 181 GK F D+ G LRY+AG ADK+ G T+ + +T EP+GV G I PWN Sbjct: 126 AGKLFAVGKARDIPGAAHLLRYYAGAADKVHGATLKMAQRMHGYTLKEPVGVVGHIVPWN 185 Query: 182 FPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVG 241 +P M +K+ PAL G +V+KPAEQTPL+AL+ L +EAG P GV+N+VPGFGPT G Sbjct: 186 YPTTMFFFKVGPALAAGCAVVVKPAEQTPLSALFYAHLAREAGVPAGVLNVVPGFGPTAG 245 Query: 242 AAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVEC 301 AA+++H ++K++FTGSTEVG+LV AA+ SNLK V+LELGGK+P IV DADLD+AV Sbjct: 246 AAVAAHMDVDKVSFTGSTEVGRLVMRAAAESNLKPVSLELGGKSPVIVFDDADLDMAVNL 305 Query: 302 AHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQ 361 + + N+G+ C A +R++V+E +Y EFV+++ E A K VGDPF+ QGPQ+D+ Q Sbjct: 306 VNFATYTNKGEICVAGTRIYVQEGIYDEFVKKAAELASKSVVGDPFNPSVSQGPQVDKDQ 365 Query: 362 FDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILK 421 ++K+L I+ GK+EGA L GG DKG +I+PT+F++V D+M IA++EIFGPV ++K Sbjct: 366 YEKVLRYIDIGKREGATLVTGGKPCGDKGYYIEPTIFTDVKDDMTIAQDEIFGPVMALMK 425 Query: 422 FKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFK 481 FK++EEVI++AN+T YGL A + TKN+D A ++ ++ +G +WINCY A APFGG+K Sbjct: 426 FKTVEEVIQKANNTRYGLAAGIVTKNIDVANTVSRSIRAGAIWINCYFAFDPDAPFGGYK 485 Query: 482 MSGNGRELGEYALAEYTEVKTVTIKL 507 MSG G+++G AL +Y + KTV L Sbjct: 486 MSGFGKDMGMDALDKYLQTKTVVTPL 511 >4V3F-A nrPDB Length = 497 Score = 618 bits (1595), Expect = e-177, Method: Composition-based stats. Identities = 207/499 (41%), Positives = 292/499 (58%), Gaps = 18/499 (3%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 A P P R ++FI+ EW E + NPST E I ++ DV+ AV AA Sbjct: 2 AFPIPAR-------QLFIDGEWREPIKKNRIPVINPSTEEIIGDIPAATAEDVEVAVVAA 54 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AF+R + W R L +A + + LET+D+GKPF A D++ Sbjct: 55 RRAFRRNN-WSATSGAHRATYLRAIAAKITEKKDHFVKLETIDSGKPFDEAVL-DIDDVA 112 Query: 139 RTLRYFAGWADKIQGK-----TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAP 193 YFAG A+ + GK T+P + +P+GV G I+PWN+PLLM WK+AP Sbjct: 113 SCFEYFAGQAEALDGKQKAPVTLPMER-FKSHVLRQPLGVVGLISPWNYPLLMATWKIAP 171 Query: 194 ALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKI 253 AL G T VLKP+E +T L G + E G PPGV+NI+ G GP GA + SHP ++KI Sbjct: 172 ALAAGCTAVLKPSELASVTCLEFGEVCNEVGLPPGVLNILTGLGPDAGAPLVSHPDVDKI 231 Query: 254 AFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQC 313 AFTGS+ G V +A++ +K VTLELGGK+P +V D D+D VE G F+ GQ Sbjct: 232 AFTGSSATGSKVMASAAQL-VKPVTLELGGKSPIVVFEDVDIDKVVEWTIFGCFWTNGQI 290 Query: 314 CTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGK 373 C+A SR+ V E + +EFV + V++ K + DPF+ GP I + Q+DKI++ I + K Sbjct: 291 CSATSRLLVHESIAAEFVDKLVKWTKNIKISDPFEEGCRLGPVISKGQYDKIMKFISTAK 350 Query: 374 KEGAKLECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKR 431 EGA + GGS E KG +I+PT+ ++++ +M+I KEE+FGPV + F S +E I Sbjct: 351 SEGATILYGGSRPEHLKKGYYIEPTIVTDISTSMQIWKEEVFGPVLCVKTFSSEDEAIAL 410 Query: 432 ANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGE 491 AN T+YGL AAVF+ +L++ ++ ALE G VW+NC + QAP+GG K SG GRELGE Sbjct: 411 ANDTEYGLAAAVFSNDLERCERITKALEVGAVWVNCSQPCFVQAPWGGIKRSGFGRELGE 470 Query: 492 YALAEYTEVKTVTIKLGDK 510 + + Y +K VT + D+ Sbjct: 471 WGIQNYLNIKQVTQDISDE 489 >4PZ2-A nrPDB Length = 534 Score = 617 bits (1591), Expect = e-177, Method: Composition-based stats. Identities = 248/484 (51%), Positives = 329/484 (67%), Gaps = 4/484 (0%) Query: 27 LEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGS 86 E++FTK+FIN + ++ SG+ F T +P T I V E DK DVD AV AA+ AF G Sbjct: 46 PEIRFTKLFINGSFVDAVSGRTFDTRDPRTGGVIASVAEADKEDVDLAVRAARAAFDHGE 105 Query: 87 PWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAG 146 W R+ RGR++ +LADLVE LAALE++D GK +D+ +LRYFAG Sbjct: 106 -WPRMSGSERGRIMARLADLVEEHAGELAALESLDAGKHPAVTRAVDVGNAAGSLRYFAG 164 Query: 147 WADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 206 ADKI G+T+ T EP+GV G I PWNFP M K+APAL G +V+KPA Sbjct: 165 AADKIHGETLKMPGQFQGHTLREPLGVAGVIIPWNFPSTMFAVKVAPALAAGCALVVKPA 224 Query: 207 EQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 EQTPL+ALYL L K+AG P GV+N+VPGFGPT GAA++SH ++ ++FTGSTEVG+L+ Sbjct: 225 EQTPLSALYLAQLAKQAGVPDGVINVVPGFGPTAGAALASHMDVDMVSFTGSTEVGRLIM 284 Query: 267 EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQV 326 +A++ SNLK V LELGGK+P IV DADLD+AVE A FFN+G+ C AASRV+V+E+V Sbjct: 285 KASAESNLKPVYLELGGKSPLIVFDDADLDMAVELAVGASFFNKGEACVAASRVYVQERV 344 Query: 327 YSEFVRRSVEYAKKRPVGDPF-DVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS- 384 Y F R E + VGDPF D + +QGPQ+D+ Q++++L I+ GK+EGA L GG Sbjct: 345 YDRFEERLAERMRSWVVGDPFSDPRADQGPQVDKAQYERVLSYIDHGKREGATLLTGGRP 404 Query: 385 -AMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 A E KG +I+PTVF+ V ++M IAKEEIFGPV ++KFK++EE I RAN T YGL A V Sbjct: 405 CAPEGKGYYIEPTVFTNVKEDMIIAKEEIFGPVMCLMKFKTVEEAIARANDTRYGLGAGV 464 Query: 444 FTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 T++LD A ++ ++ +G VW+NCY A+ + PFGG KMSG G++ G +AL +Y VK+V Sbjct: 465 VTRDLDVANRVVRSVRAGVVWVNCYFAMGSDCPFGGRKMSGFGKDEGMHALDKYLAVKSV 524 Query: 504 TIKL 507 L Sbjct: 525 VTPL 528 >4CAZ-A nrPDB Length = 490 Score = 611 bits (1575), Expect = e-175, Method: Composition-based stats. Identities = 203/486 (41%), Positives = 288/486 (59%), Gaps = 7/486 (1%) Query: 28 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 87 + K++I + E+ SG F T NP+ E + +V+ + DV++AV++A + Sbjct: 3 RFEEQKLYIGGRYVEASSGATFETINPANGEVLAKVQRASREDVERAVQSAVEGQK---V 59 Query: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147 W + A+ R R+L + D++ LAALET+DTGKP +D+ L Y+AG Sbjct: 60 WAAMTAMQRSRILRRAVDILRERNDELAALETLDTGKPLAETRSVDIVTGADVLEYYAGL 119 Query: 148 ADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 I+G+ IP + +TR EP+GV I WN+P+ + +WK APAL GN M+ KP+E Sbjct: 120 VPAIEGEQIPLRETSFVYTRREPLGVVAGIGAWNYPVQIALWKSAPALAAGNAMIFKPSE 179 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 TPLTAL L + EAG P GV N++ G G VG ++ HP I KI+FTG T GK V Sbjct: 180 VTPLTALKLAEIYTEAGVPDGVFNVLTGSGREVGQWLTEHPLIEKISFTGGTSTGKKVMA 239 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 +AS S+LK VT+ELGGK+P I+ DADLD A + A FF+ GQ CT +RVF+ Sbjct: 240 SASSSSLKEVTMELGGKSPLIIFPDADLDRAADIAVMANFFSSGQVCTNGTRVFIHRSQQ 299 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 + F + +E ++ +GDP D T GP + + +L IESGK + A+L CGG + Sbjct: 300 ARFEAKVLERVQRIRLGDPQDENTNFGPLVSFPHMESVLGYIESGKAQKARLLCGGERVT 359 Query: 388 D----KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 D KG ++ PTVF++ D+M I +EEIFGPV IL + +E I+RAN T+YGL A V Sbjct: 360 DGAFGKGAYVAPTVFTDCRDDMTIVREEIFGPVMSILVYDDEDEAIRRANDTEYGLAAGV 419 Query: 444 FTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 T++L +A + LE+G WIN + A+ P GG+K SG GRE G LA YT +K+V Sbjct: 420 VTQDLARAHRAIHRLEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLAHYTRIKSV 479 Query: 504 TIKLGD 509 ++LGD Sbjct: 480 QVELGD 485 >4O6R-A nrPDB Length = 496 Score = 609 bits (1570), Expect = e-174, Method: Composition-based stats. Identities = 200/485 (41%), Positives = 291/485 (60%), Gaps = 8/485 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 T++FI+ + ++ NP I ++ DVD AV+AA AF W + Sbjct: 11 TQLFIDGRFVDAVDRGTIDVLNPHDGSVITKIAAATAADVDLAVDAATRAF---PAWSAM 67 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 A RGRLL +LAD +E + LA LE++DTG P + +D+ RYF G ADK+ Sbjct: 68 PAAERGRLLLRLADAIEANTEALAQLESLDTGHPIRDSRALDVPRTAACFRYFGGMADKL 127 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 QG IP D + + + PIGV G I PWNFPL+ WK+ PAL GNT+VLKP+E TPL Sbjct: 128 QGSVIPVDTGFLNYVQRAPIGVVGQIVPWNFPLMFTSWKMGPALAAGNTVVLKPSEITPL 187 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L + L+ E GFP GVVNIVPG+G T G ++ HP + KIAFTGST G+ + E AS+ Sbjct: 188 STLRIVELMAEVGFPAGVVNIVPGYGHTAGQRLAEHPGVGKIAFTGSTATGRRIVE-ASQ 246 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 NLKRV LELGGK IV DA+LD A+ A +F NQGQ C A SR+ + E++ F+ Sbjct: 247 GNLKRVQLELGGKGANIVFDDANLDAAINGAAWAIFHNQGQACIAGSRLVLHERIADAFL 306 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK-- 389 R V A +G+P D TE GP ++ D++L ++ +++G ++ GGSA +D Sbjct: 307 ERFVALASSIRIGNPLDPNTEMGPLTSKQHLDRVLSYVDVAREQGGRVLTGGSAPQDPAL 366 Query: 390 --GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G +++PT+ R+A+EE+FGP +L+F S +E + AN+T+YGL + ++T + Sbjct: 367 ANGYYVRPTIVEAKHATDRVAQEEVFGPFVTVLRFGSDDEALAIANATEYGLGSGLWTND 426 Query: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 L +A ++A+ +++G WINCY + +PFGG SG GRE+G A+ +YTE ++V + + Sbjct: 427 LSRAHRMAARIDAGMCWINCYKRVNPGSPFGGVGKSGYGREMGFEAMHDYTEARSVWVNV 486 Query: 508 GDKNP 512 P Sbjct: 487 DGNVP 491 >3RHO-A nrPDB Length = 517 Score = 595 bits (1534), Expect = e-170, Method: Composition-based stats. Identities = 227/495 (45%), Positives = 328/495 (66%), Gaps = 8/495 (1%) Query: 20 LPRPIRNLEVKFT-KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 + + + L ++ ++FI E+ +++ K + T NP+ IC+V DVDKAV AA Sbjct: 24 VEKAVNKLTLQMPYQLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAA 83 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AF+ G W +++A RGRLL++LAD++E+ + LA +E +D G + A + I Sbjct: 84 KEAFENGL-WGKINARDRGRLLYRLADVMEQHQEELATIEALDAGAVYTLALKTHVGMSI 142 Query: 139 RTLRYFAGWADKIQGKTIPTDDNV----VCFTRHEPIGVCGAITPWNFPLLMLVWKLAPA 194 +T RYFAGW DKIQG TIP + + T+ EP+GVCG + PWN+PL+ML WK A Sbjct: 143 QTFRYFAGWCDKIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAAC 202 Query: 195 LCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIA 254 L GNT+V+KPA+ TPLTAL L +AG P GVVNI+PG G VG +S HP + KI Sbjct: 203 LAAGNTVVIKPAQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIG 262 Query: 255 FTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCC 314 FTGSTEVGK + ++ + SN+K+V+L+LGGK+P I+ AD DL+ AV+ VFFN+G+ C Sbjct: 263 FTGSTEVGKHIMKSCALSNVKKVSLQLGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENC 322 Query: 315 TAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKK 374 AA R+FVEE ++++FV++ VE +K +G+P + T GPQ + K++E + G K Sbjct: 323 IAAGRLFVEESIHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVK 382 Query: 375 EGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFK--SIEEVIKRA 432 EGA L CGG+ + G F +PTVF++V D+M IAKEE FGP+ I +F ++ V+ RA Sbjct: 383 EGATLVCGGNQVPRPGFFFQPTVFTDVEDHMYIAKEESFGPIMIISRFADGDVDAVLSRA 442 Query: 433 NSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEY 492 N+T++GL + VFT++++KAL ++ L++GTV+IN YN APFGGFK SG G++LGE Sbjct: 443 NATEFGLASGVFTRDINKALYVSDKLQAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEA 502 Query: 493 ALAEYTEVKTVTIKL 507 AL EY +KTVT + Sbjct: 503 ALNEYLRIKTVTFEY 517 >3IWK-A nrPDB Length = 503 Score = 590 bits (1521), Expect = e-169, Method: Composition-based stats. Identities = 200/493 (40%), Positives = 284/493 (57%), Gaps = 12/493 (2%) Query: 27 LEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVA--FQR 84 + V ++FI+ EW K+ NPST I ++ K DVD AV+AA+ A + Sbjct: 3 ITVSSRQLFIDGEWRVPILNKRIPNINPSTENIIGDIPAATKEDVDLAVDAAKRAISRKN 62 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 G W R R L +A ++ + L LE++D GKP A DL+ + Y+ Sbjct: 63 GRDWSAASGSLRARYLRAIAAKIKEKKDELGKLESIDCGKPLEEA-LADLDDVVACFEYY 121 Query: 145 AGWADKIQGK-----TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGN 199 AG A+++ K ++P D + EPIGV ITPWN+P LM WK+APAL G Sbjct: 122 AGLAEELDSKQKAPISLPMDT-FKSYILKEPIGVVALITPWNYPFLMATWKIAPALAAGC 180 Query: 200 TMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 +LKP+E +T L LG + KE G P GV+NIV G G GA+++SHP ++KI+FTGS+ Sbjct: 181 AAILKPSELASVTCLELGEICKEVGLPRGVLNIVTGLGHEAGASLASHPDVDKISFTGSS 240 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319 G + A++ +K V+LELGGK+P +V D DLD E G FF GQ C+A SR Sbjct: 241 ATGSKIMTTAAQL-VKPVSLELGGKSPIVVFEDVDLDKVAEWTVFGCFFTNGQICSATSR 299 Query: 320 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL 379 + V E + EFV + V++A+ + DP + GP + + Q+ K+L I S K EGA + Sbjct: 300 LIVHESIAVEFVDKLVKWAENIKISDPLEEGCRLGPIVSEAQYKKVLNCISSAKSEGATI 359 Query: 380 ECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 GG E KG F++PT+ ++VT +M+I +EE+FGPV + F + EE I AN T Y Sbjct: 360 LTGGRRPEHLKKGYFVEPTIITDVTTSMQIWREEVFGPVLAVKTFSTEEEAINLANDTHY 419 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL +AV + +L++ +L+ AL++G VWINC + QAP+GG K SG GRELGE+ L Y Sbjct: 420 GLGSAVMSNDLERCERLSKALQAGIVWINCAQPSFIQAPWGGIKRSGFGRELGEWGLENY 479 Query: 498 TEVKTVTIKLGDK 510 VK VT D+ Sbjct: 480 LSVKQVTRYTSDE 492 >3IWJ-A nrPDB Length = 503 Score = 583 bits (1503), Expect = e-167, Method: Composition-based stats. Identities = 201/494 (40%), Positives = 292/494 (59%), Gaps = 12/494 (2%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR- 84 ++ + ++FIN +W K+ NP+T+ I ++ K DVD AV AA+ A R Sbjct: 2 DIPIPTRQLFINGDWKAPVLNKRIPVINPATQNIIGDIPAATKEDVDVAVAAAKTALTRN 61 Query: 85 -GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 G+ W R R L +A V + LA LE++D GKP A + D++ Y Sbjct: 62 KGADWATASGAVRARYLRAIAAKVTEKKPELAKLESIDCGKPLDEAAW-DIDDVAGCFEY 120 Query: 144 FAGWADKIQGK-----TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCG 198 +A A+K+ + ++P D EPIGV G ITPWN+P+LM WK+APAL G Sbjct: 121 YADLAEKLDARQKAPVSLPMDT-FKSHVLREPIGVVGLITPWNYPMLMATWKVAPALAAG 179 Query: 199 NTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 258 +LKP+E LT L LG + KE G PPGV+NI+ G GP GA +++HP ++K+AFTGS Sbjct: 180 CAAILKPSELASLTCLELGEICKEVGLPPGVLNILTGLGPEAGAPLATHPDVDKVAFTGS 239 Query: 259 TEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS 318 + G + AA++ +K V+LELGGK+P +V D DLD A E A G F+ GQ C+A S Sbjct: 240 SATGSKIMTAAAQL-VKPVSLELGGKSPLVVFEDVDLDKAAEWAIFGCFWTNGQICSATS 298 Query: 319 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 R+ + E + +EF+ R V++ K + DP + GP + + Q++KIL+ + + K EGA Sbjct: 299 RLILHESIATEFLNRIVKWIKNIKISDPLEEGCRLGPVVSEGQYEKILKFVSNAKSEGAT 358 Query: 379 LECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTD 436 + GGS E KG FI+PT+ ++VT NM+I +EE+FGPV + F + EE I AN T Sbjct: 359 ILTGGSRPEHLKKGFFIEPTIITDVTTNMQIWREEVFGPVLCVKTFSTEEEAIDLANDTV 418 Query: 437 YGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAE 496 YGL AAV + +L++ ++ A ++G VW+NC + QAP+GG K SG GRELGE+ L Sbjct: 419 YGLGAAVISNDLERCERVTKAFKAGIVWVNCSQPCFTQAPWGGVKRSGFGRELGEWGLDN 478 Query: 497 YTEVKTVTIKLGDK 510 Y VK VT + ++ Sbjct: 479 YLSVKQVTQYISEE 492 >4GO4-A nrPDB Length = 495 Score = 582 bits (1501), Expect = e-166, Method: Composition-based stats. Identities = 200/483 (41%), Positives = 292/483 (60%), Gaps = 9/483 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 +++I+ + ++ +G +P I + + DVD AV AA+ AF W L Sbjct: 3 NQLYIDGRFVDAVAGGTIDVVSPHDGSLITRIAAAEAADVDLAVAAAKRAF---PAWSAL 59 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 A RGRLL +LAD +E LA LE+++TG P + +D+ RYF G ADKI Sbjct: 60 GAAERGRLLLKLADRIEECSEELAQLESLNTGHPIRDSRGLDVPRTAACFRYFGGMADKI 119 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 +G IP D + + + +PIGV I PWNFPL+ WK+ PAL GNT+V+KP+E TPL Sbjct: 120 EGSVIPVDAGFLNYVQRKPIGVVAQIVPWNFPLMFTSWKMGPALAAGNTIVIKPSEITPL 179 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L + L+ E GFP GVVN+VPG+G T G A++ H + KIAFTGST G+ + E AS+ Sbjct: 180 STLRIVELMTEVGFPKGVVNVVPGYGHTAGQALAEHLDVGKIAFTGSTATGRRIVE-ASK 238 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 SNLKR+ LELGGK IV DA+++ AV A +F NQGQ C A SR+ + + + +F+ Sbjct: 239 SNLKRIQLELGGKGANIVFEDANIEAAVNGAAWAIFHNQGQACIAGSRLILHKDIADQFL 298 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK-- 389 R + AK +GDP D +TE GP + D++L I+ ++G K+ GG A +DK Sbjct: 299 ERFIALAKSIRLGDPMDPETEMGPLTSALRRDRVLSYIDIAIEQGGKVLAGGKAPDDKAL 358 Query: 390 --GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G +++PTV E R+ +EE+FGP +++F S EE + AN+T+YGL + ++T+N Sbjct: 359 ANGFYVEPTVV-EAKPQDRVCQEEVFGPFVTVVRFSSDEEALAIANNTEYGLGSGLWTQN 417 Query: 448 LDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 L +A K+A A+ +G WINCY + +PFGG SG GRE+G A+ +YTE ++V + + Sbjct: 418 LARAHKMAHAIHAGMCWINCYKRVSPGSPFGGVGQSGYGREMGFEAIHDYTEARSVWVNV 477 Query: 508 GDK 510 K Sbjct: 478 DAK 480 >4MPY-A nrPDB Length = 520 Score = 581 bits (1498), Expect = e-166, Method: Composition-based stats. Identities = 197/495 (39%), Positives = 296/495 (59%), Gaps = 11/495 (2%) Query: 23 PIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAF 82 + L+ + +I+ EW ES + NP +E I V EG K D ++A+ AA+ AF Sbjct: 24 AMELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGTKEDAERAILAARRAF 83 Query: 83 QRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLR 142 + G W + A +RG+ + +AD ++ R LA LET+DTGK ++ D++ Sbjct: 84 ESGE-WSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTLEESY-ADMDDIHNVFM 141 Query: 143 YFAGWADKIQGKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTM 201 YFAG ADK G+ I + + EP+GV ITPWN+PLL WK+APAL G ++ Sbjct: 142 YFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPLLQASWKIAPALATGCSL 201 Query: 202 VLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEV 261 V+KP+E TPLT + + L++E GFP G +N++ G G VG +S H +++ ++FTG E Sbjct: 202 VMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGDVMSGHKEVDLVSFTGGIET 261 Query: 262 GKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVF 321 GK + + A+ N+ + LELGGKNP I+ DAD +LAV+ A G +F+ GQ C+A SR+ Sbjct: 262 GKHIMKNAAN-NVTNIALELGGKNPNIIFDDADFELAVDQALNGGYFHAGQVCSAGSRIL 320 Query: 322 VEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLEC 381 V+ + +F + ++ KK +G+ FD TE GP I + +KI ++ K EGA + Sbjct: 321 VQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVISTEHRNKIESYMDVAKAEGATIAV 380 Query: 382 GGSAMEDK----GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDY 437 GG + GLF +PTV + +MRI +EE+FGPV + F++ +E I+ AN + Y Sbjct: 381 GGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVFGPVVTVEGFETEQEAIQLANDSIY 440 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEY 497 GL AVF+K++ KA ++A+ L+ GTVWIN ++ +AQAP+GG+K SG GRELG+ L EY Sbjct: 441 GLAGAVFSKDIGKAQRVANKLKLGTVWINDFHPYFAQAPWGGYKQSGIGRELGKEGLEEY 500 Query: 498 TEVKTVTIKLGDKNP 512 K + L + NP Sbjct: 501 LVSKHI---LTNTNP 512 >3JZ4-A nrPDB Length = 481 Score = 578 bits (1491), Expect = e-165, Method: Composition-based stats. Identities = 184/485 (37%), Positives = 269/485 (55%), Gaps = 6/485 (1%) Query: 24 IRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQ 83 + + + + IN EW ++ +G+ NP+ +++ V + + A++AA A Sbjct: 2 LNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRAL- 60 Query: 84 RGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 WR L A R +L +L+ + LA L T++ GKP A ++ + + Sbjct: 61 --PAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKG-EISYAASFIEW 117 Query: 144 FAGWADKIQGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMV 202 FA +I G TIP + +PIGV AITPWNFP M+ K PAL G TMV Sbjct: 118 FAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMV 177 Query: 203 LKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG 262 LKPA QTP +AL L L AG P GV N+V G VG ++S+P + K++FTGSTE+G Sbjct: 178 LKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIG 237 Query: 263 KLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFV 322 + + E ++ ++K+V+LELGG P IV DADLD AVE A F N GQ C A+R++V Sbjct: 238 RQLMEQCAK-DIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYV 296 Query: 323 EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECG 382 ++ VY F + + K +GD D GP ID+K K+ E I ++GA++ CG Sbjct: 297 QDGVYDRFAEKLQQAMSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCG 356 Query: 383 GSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 G A E G F +PT+ +V N +++KEE FGP+ P+ +FK +VI +AN T++GL A Sbjct: 357 GKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAY 416 Query: 443 VFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKT 502 + ++L + ++ ALE G V IN APFGG K SG GRE +Y + +Y E+K Sbjct: 417 FYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKY 476 Query: 503 VTIKL 507 + I L Sbjct: 477 MCIGL 481 >4O5H-A nrPDB Length = 511 Score = 572 bits (1474), Expect = e-163, Method: Composition-based stats. Identities = 221/496 (44%), Positives = 302/496 (60%), Gaps = 8/496 (1%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAA 78 AL R K ++ I EW ++ SG++ NP+ I V E D+ DV +AV AA Sbjct: 18 ALLDATRAFLAKPKQMLIGAEWSDAASGRQLDVVNPADGTVIARVPEADERDVQQAVAAA 77 Query: 79 QVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCI 138 + AF G PWR R RL+ LADL+E + LA +E++D GKP + A +D+ Sbjct: 78 RRAFDAG-PWRTAKTTDRERLMLVLADLIEANARELAEIESLDNGKPVMVAQGLDVAMAA 136 Query: 139 RTLRYFAGWADKIQGKTIP------TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLA 192 + RY AGWA KI+G I D + +TR EP+GV GAI PWNFPLLM WK+A Sbjct: 137 QCFRYMAGWATKIEGSVIDAGMPYLPDSEIFAYTRKEPVGVVGAIIPWNFPLLMAAWKIA 196 Query: 193 PALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINK 252 PAL G T+VLKPAE TPL+AL LG LI+ AGFP GVVNIV G+G T GAA+S P+I+K Sbjct: 197 PALATGCTVVLKPAEDTPLSALRLGELIQAAGFPDGVVNIVTGYGHTAGAALSRDPRIDK 256 Query: 253 IAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQ 312 IAFTGST+ GK + A+ N+ R++LELGGK+P IV D DLD A + +FFNQGQ Sbjct: 257 IAFTGSTQTGKTIGH-AALDNMTRMSLELGGKSPVIVLPDVDLDKAAQGVANAIFFNQGQ 315 Query: 313 CCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESG 372 CTA SR ++ +V+ + R + A +G D T+ GP + KQ +++ I+SG Sbjct: 316 VCTAGSRAYIHSKVFDGVIERVAKIAASLKIGPGMDPATQIGPLVSAKQRERVCGYIDSG 375 Query: 373 KKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRA 432 EGA+ GG A++ G F++PTV + T MR+ +EEIFGPV + F ++ ++ A Sbjct: 376 FGEGARAAAGGRAIDGPGFFVEPTVLVDTTQAMRVVREEIFGPVLVAMPFDDVDTAVQLA 435 Query: 433 NSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEY 492 N T YGL A++++ +L KL + +GTVW+NC++ L PFGG K SG GRELG Sbjct: 436 NDTPYGLGASIWSNDLSAIHKLVPRIAAGTVWVNCHSLLDNALPFGGMKQSGFGRELGRA 495 Query: 493 ALAEYTEVKTVTIKLG 508 + +YTE K+V + Sbjct: 496 VIDQYTESKSVMMNYA 511 >4I8P-A nrPDB Length = 520 Score = 570 bits (1470), Expect = e-163, Method: Composition-based stats. Identities = 201/507 (39%), Positives = 292/507 (57%), Gaps = 20/507 (3%) Query: 13 PDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVD 72 P+ PA+ V ++F++ EW G++ NP+T I E+ G DVD Sbjct: 14 PNSASPAM--------VPLRQLFVDGEWRPPAQGRRLPVVNPTTEAHIGEIPAGTAEDVD 65 Query: 73 KAVEAAQVAFQR--GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAF 130 AV AA+ A +R G W R R + L +A V + LA LE +D GKP+ A Sbjct: 66 AAVAAARAALKRNRGRDWARAPGAVRAKYLRAIAAKVIERKPELAKLEALDCGKPYDEAA 125 Query: 131 FIDLEGCIRTLRYFAGWADKIQGK-----TIPTDDNVVCFTRHEPIGVCGAITPWNFPLL 185 + D++ YFA A+ + + ++P + C R EPIGV G ITPWN+PLL Sbjct: 126 W-DMDDVAGCFEYFADQAEALDKRQNSPVSLPMET-FKCHLRREPIGVVGLITPWNYPLL 183 Query: 186 MLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAIS 245 M WK+APAL G T VLKP+E +T L L + KE G P GV+NIV G GP GA +S Sbjct: 184 MATWKIAPALAAGCTAVLKPSELASVTCLELADICKEVGLPSGVLNIVTGLGPDAGAPLS 243 Query: 246 SHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQG 305 +HP ++K+AFTGS E GK + +A+ +K VTLELGGK+P +V D D+D AVE G Sbjct: 244 AHPDVDKVAFTGSFETGKKIMASAA-PMVKPVTLELGGKSPIVVFDDVDIDKAVEWTLFG 302 Query: 306 VFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKI 365 F+ GQ C+A SR+ + ++ +F R V +AK V DP + GP + + Q++KI Sbjct: 303 CFWTNGQICSATSRLLIHTKIAKKFNERMVAWAKNIKVSDPLEEGCRLGPVVSEGQYEKI 362 Query: 366 LELIESGKKEGAKLECGG--SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFK 423 + I + K +GA + GG A +KG FI+PT+ +++T +M I +EE+FGPV + +F Sbjct: 363 KKFISNAKSQGATILTGGVRPAHLEKGFFIEPTIITDITTSMEIWREEVFGPVLCVKEFS 422 Query: 424 SIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMS 483 + +E I+ AN T YGL AV + + ++ +L+ +++G +W+NC + QAP+GG K S Sbjct: 423 TEDEAIELANDTQYGLAGAVISGDRERCQRLSEEIDAGCIWVNCSQPCFCQAPWGGNKRS 482 Query: 484 GNGRELGEYALAEYTEVKTVTIKLGDK 510 G GRELGE + Y VK VT + D+ Sbjct: 483 GFGRELGEGGIDNYLSVKQVTEYISDE 509 >6B4R-B nrPDB Length = 497 Score = 570 bits (1470), Expect = e-163, Method: Composition-based stats. Identities = 209/494 (42%), Positives = 297/494 (60%), Gaps = 5/494 (1%) Query: 17 PPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVE 76 ++L+++ + F+N E+ + SG+ F +P + +V D D ++AV+ Sbjct: 6 RADWEARAKDLKIE-GRAFVNGEYSNAASGETFDCLSPVDGRFLAKVASCDLADAEQAVK 64 Query: 77 AAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEG 136 A+ AF G W RL R + + + ADL+ + LA LET+D GKP + ID+ Sbjct: 65 VARNAFDSG-AWSRLAPAKRKQTMIRFADLLLENAEELALLETLDMGKPISDSLHIDVAS 123 Query: 137 CIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALC 196 +LR+ A DKI + T + EP+GV AI PWNFPLLM WKL PAL Sbjct: 124 AANSLRWSAEAIDKIYDEVAATPHAELGLVTREPVGVVAAIVPWNFPLLMSCWKLGPALA 183 Query: 197 CGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFT 256 GN+++LKP+E++PLTA+ + L EAG P GV N++PG+G TVG A++ H ++ + FT Sbjct: 184 TGNSVILKPSEKSPLTAIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHMDVDTLVFT 243 Query: 257 GSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCT 315 GST++ K + A SN+KRV LE GGK+P IV ADA DL A E A + FNQG+ CT Sbjct: 244 GSTKIAKQLMVYAGESNMKRVWLEAGGKSPNIVFADAPDLKAAAEAAAGAIAFNQGEVCT 303 Query: 316 AASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE 375 A SR+ VE + +F+ +E K G+P D +T G +D +Q + +L IE+G + Sbjct: 304 AGSRLLVERSIKDKFLPLVIEALKGWKPGNPLDPETNVGALVDTQQMNTVLSYIEAGHND 363 Query: 376 GAKLECGGSAM--EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRAN 433 GAKL GG E G +++PT+F VT+ M+IA+EEIFGPV +++F+ EE ++ AN Sbjct: 364 GAKLVAGGKRTLEETGGTYVEPTIFDGVTNAMKIAREEIFGPVLSVIEFEDAEEAVRIAN 423 Query: 434 STDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYA 493 T YGL AAV+T NL KA A AL +G+VW+N Y+ APFGGFK SGNGR+ +A Sbjct: 424 DTPYGLAAAVWTSNLSKAHLTAKALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHA 483 Query: 494 LAEYTEVKTVTIKL 507 +YTE+K IKL Sbjct: 484 FDKYTELKATWIKL 497 >6QAO-A nrPDB Length = 508 Score = 570 bits (1469), Expect = e-163, Method: Composition-based stats. Identities = 172/483 (35%), Positives = 269/483 (55%), Gaps = 13/483 (2%) Query: 34 IFINNEWHESKSGK-KFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 + E P+T I + +V+ AV+ A+ AF+ W + Sbjct: 27 NYRGGARVEPADASGTEKAFEPATGRVIATFTCSGEKEVNLAVQNAKAAFKI---WSQKS 83 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 + R R+L + A ++ +A +E ++ GK A D++ + L Y+AG A + Sbjct: 84 GMERCRILLEAARIIREREDEIATMECINNGKSIFEARL-DIDISWQCLEYYAGLAASMA 142 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 G+ I +TR EP+GVC I WN+P + WK APAL CGN MV KP+ TP++ Sbjct: 143 GEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIASWKSAPALACGNAMVFKPSPFTPVS 202 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 AL L + EAG PPG+ N+V G G G + HP + K++FTGS G + E +++ Sbjct: 203 ALLLAEIYSEAGVPPGLFNVVQG-GAATGQFLCQHPDVAKVSFTGSVPTGMKIMEMSAK- 260 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 +K VTLELGGK+P I+ +D D++ AV+ A F QGQ C +RVFV++++ +F Sbjct: 261 GIKPVTLELGGKSPLIIFSDCDMNNAVKGALMANFLTQGQVCCNGTRVFVQKEILDKFTE 320 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS------AM 386 V+ ++ +GDP T GP I++ +++L ++ K++GAK+ CGG Sbjct: 321 EVVKQTQRIKIGDPLLEDTRMGPLINRPHLERVLGFVKVAKEQGAKVLCGGDIYVPEDPK 380 Query: 387 EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 G +++P V + D+M KEEIFGPV IL F + EV++RAN T +GL A VFT+ Sbjct: 381 LKDGYYMRPCVLTNCRDDMTCVKEEIFGPVMSILSFDTEAEVLERANDTTFGLAAGVFTR 440 Query: 447 NLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 ++ +A ++ + L++GT +IN YN + PFGG+K SG GRE G + Y+++KTV ++ Sbjct: 441 DIQRAHRVVAELQAGTCFINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVE 500 Query: 507 LGD 509 +GD Sbjct: 501 MGD 503 >4QYJ-A nrPDB Length = 516 Score = 569 bits (1468), Expect = e-163, Method: Composition-based stats. Identities = 212/485 (43%), Positives = 297/485 (61%), Gaps = 10/485 (2%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 ++ I +W ++SGK NP+T + + EV +GD DV+ AVE+A A R WRR Sbjct: 34 PHQMLIGGQWVSAQSGKTLNVYNPATGDILTEVPDGDVEDVNAAVESA-AATLRSDTWRR 92 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 + +R R+L +LADL+E LA LET++ GK +++ +++ + LRY AGWA K Sbjct: 93 MPPSARERILLRLADLLEVHGDELARLETLNNGKLLIYSKLMEVGASAQWLRYMAGWATK 152 Query: 151 IQGKTI------PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 + G T+ P + T+ P+GV AI PWNFPLLM VWK+APAL CGNT+VLK Sbjct: 153 LTGSTLDLSLPLPPEVRSRASTQRVPVGVVAAIIPWNFPLLMAVWKIAPALACGNTVVLK 212 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKL 264 PAE+TPLTAL L L EAG P G +N+V G G T G A+ HP++ K+AFTGSTEVG++ Sbjct: 213 PAEETPLTALRLAELAMEAGLPAGALNVVTGRGETAGDALVRHPKVAKVAFTGSTEVGRI 272 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + A RS LK V+LELGGK+P IV AD D A E A +FFN GQ CTA SR++V E Sbjct: 273 IGSACGRS-LKAVSLELGGKSPVIVLADCDPQEAAEGAAAAIFFNHGQVCTAGSRLYVHE 331 Query: 325 QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG- 383 +Y + ++R + VG + GP + +K + +L I +G ++GA L CGG Sbjct: 332 SIYEDVIQRLAVIGESIVVGSGLEQGVHMGPMVSKKHHENVLRHIRNGIEDGADLICGGT 391 Query: 384 SAMEDKGLFIKPTVFSE-VTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAA 442 A +G F+KPT+F+ ++R+ +E+FGPV F I EV+ AN + YGL A+ Sbjct: 392 EAPCAQGFFVKPTIFANREKKDIRLLSQEVFGPVLVATPFSDIAEVVNEANRSVYGLGAS 451 Query: 443 VFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKT 502 ++T +L AL++ LE+GTVW+N +N + PFGGFK SG GRE G A+ YT ++ Sbjct: 452 IWTNDLSAALRINDELEAGTVWVNTHNMVDPNLPFGGFKDSGVGREHGAAAIEHYTTTRS 511 Query: 503 VTIKL 507 + I Sbjct: 512 LVIAY 516 >1BPW-A nrPDB Length = 503 Score = 569 bits (1467), Expect = e-162, Method: Composition-based stats. Identities = 184/499 (36%), Positives = 289/499 (57%), Gaps = 14/499 (2%) Query: 19 ALPRPIR-NLEVKFTKIFINNEWHESKSGKK-FATCNPSTREQICEVEEGDKPDVDKAVE 76 ++P ++ V + +SK G P+T +C++ +VD+AV+ Sbjct: 6 SMPSASTGSVVVTDDLNYWGGRRIKSKDGATTEPVFEPATGRVLCQMVPCGAEEVDQAVQ 65 Query: 77 AAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEG 136 +AQ A+ + W ++ + R R++ + A ++ R +A LE ++ GK A + D++ Sbjct: 66 SAQAAYLK---WSKMAGIERSRVMLEAARIIRERRDNIAKLEVINNGKTITEAEY-DIDA 121 Query: 137 CIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALC 196 + + Y+AG A + G+ I +TR EP+GVC I WN+P ++ WK APAL Sbjct: 122 AWQCIEYYAGLAPTLSGQHIQLPGGAFAYTRREPLGVCAGILAWNYPFMIAAWKCAPALA 181 Query: 197 CGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFT 256 CGN +V KP+ TP+T + L + EAG P G+VN+V G G G+ + HP + K++FT Sbjct: 182 CGNAVVFKPSPMTPVTGVILAEIFHEAGVPVGLVNVVQG-GAETGSLLCHHPNVAKVSFT 240 Query: 257 GSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTA 316 GS GK V E ++++ +K VTLELGGK+P ++ D +L+ AV A F QGQ CT Sbjct: 241 GSVPTGKKVMEMSAKT-VKHVTLELGGKSPLLIFKDCELENAVRGALMANFLTQGQVCTN 299 Query: 317 ASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEG 376 +RVFV+ ++ +F+ V+ K VGDP +T G I + Q DK+L + KKEG Sbjct: 300 GTRVFVQREIMPQFLEEVVKRTKAIVVGDPLLTETRMGGLISKPQLDKVLGFVAQAKKEG 359 Query: 377 AKLECGGSAME------DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIK 430 A++ CGG + G F+ P V D+M KEEIFGPV +L F + EEV++ Sbjct: 360 ARVLCGGEPLTPSDPKLKNGYFMSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQ 419 Query: 431 RANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELG 490 RAN+T +GL + VFT+++ +A ++A+ LE+GT +IN Y+ + PFGG+KMSG GRE G Sbjct: 420 RANNTTFGLASGVFTRDISRAHRVAANLEAGTCYINTYSISPVEVPFGGYKMSGFGRENG 479 Query: 491 EYALAEYTEVKTVTIKLGD 509 + + Y+++KTV +++GD Sbjct: 480 QATVDYYSQLKTVIVEMGD 498 >4I8Q-A nrPDB Length = 514 Score = 568 bits (1464), Expect = e-162, Method: Composition-based stats. Identities = 183/495 (36%), Positives = 283/495 (57%), Gaps = 10/495 (2%) Query: 23 PIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAF 82 RN+ + +++I EW E + NP+T E I ++ DVD AVEAA+ A Sbjct: 15 ANRNVPIPRRQLYIGGEWREPVKKNRIPIINPATEEIIGDIPAATAEDVDIAVEAARKAI 74 Query: 83 QRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLR 142 R W R + L +A V ++ LA LE++D+GK + D++ Sbjct: 75 AR-DDWGSTTGAQRAKYLRAIAAKVLEKKSVLATLESLDSGKTLYESA-ADMDDVAGCFE 132 Query: 143 YFAGWADKIQGKTIPT----DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCG 198 Y+AG A+ + + + D+ + EP+GV G ITPWN+PLLM +WK+APAL G Sbjct: 133 YYAGLAEALDSRRMTPVNLNSDSYKSYVLREPLGVVGLITPWNYPLLMAIWKVAPALAAG 192 Query: 199 NTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 258 +LKP+E +T L LG + +E G P G +NI+ G GP G ++SHP ++KI+FTGS Sbjct: 193 CAAILKPSELASITCLELGEICREIGLPSGALNILTGLGPEAGGPLASHPHVDKISFTGS 252 Query: 259 TEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADAD-LDLAVECAHQGVFFNQGQCCTAA 317 G + AA++ +K V+L LGGK+P +V D D LD+A E G+F N GQ C+A Sbjct: 253 GPTGSKIMTAAAQL-VKPVSLALGGKSPIVVFDDIDNLDIAAEWTLFGIFANTGQVCSAT 311 Query: 318 SRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGA 377 SR+ V+E + S F+ R +++ K + DP + + GP + Q++K+L+ I + K EGA Sbjct: 312 SRLIVQENIASAFMDRLLKWTKNIKISDPLEEDCKLGPVVSAGQYEKVLKFISNAKSEGA 371 Query: 378 KLECGGSAMED--KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 + CGG + KG +++PT+ ++V +M I KEE+FGPV + FK+ E+ I+ AN T Sbjct: 372 TILCGGERPQHLKKGYYVQPTIITDVNTSMEIWKEEVFGPVLCVKTFKTEEQAIELANDT 431 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL AAV +K++ + + A ++G +WINC + + P+GG K SG GR+LG++ L Sbjct: 432 KYGLGAAVMSKDVKRCERFTKAFQTGIIWINCSQPTFNELPWGGKKRSGFGRDLGKWGLE 491 Query: 496 EYTEVKTVTIKLGDK 510 + +K VT + Sbjct: 492 NFLNIKQVTEYTSAE 506 >5IUV-A nrPDB Length = 497 Score = 566 bits (1460), Expect = e-162, Method: Composition-based stats. Identities = 207/486 (42%), Positives = 293/486 (60%), Gaps = 5/486 (1%) Query: 25 RNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR 84 +NL+++ + FI E+ + SG+ F +P + +V D D +AVE+A+ AF Sbjct: 14 QNLKIE-GRAFIQGEYTAAASGETFDCISPVDGRLLAKVASCDAADAQRAVESARSAFDS 72 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 G W RL R + + A L+E++ LA LET+D GKP + +D+ G R L + Sbjct: 73 G-AWSRLAPAKRKATMIRFAGLLEQNAEELALLETLDMGKPISDSLGVDIPGGARALSWS 131 Query: 145 AGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 DK+ + T + + EP+GV AI PWNFPL+M WKL PAL GN++VLK Sbjct: 132 GEAIDKLYDEVAATPHDQLGLVTREPVGVVAAIVPWNFPLMMACWKLGPALSTGNSVVLK 191 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKL 264 P+E++PLTA+ + L EAG P GV+N++PG+G TVG A++ H ++ + FTGST++ K Sbjct: 192 PSEKSPLTAIRIAQLAIEAGIPAGVLNVLPGYGHTVGKALALHMDVDTVVFTGSTKIAKQ 251 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 + A SN+KRV LE GGK+P IV ADA DL A + A + FNQG+ CTA SR+ VE Sbjct: 252 LMIYAGESNMKRVWLEAGGKSPNIVFADAPDLQAAADSAASAIAFNQGEVCTAGSRLLVE 311 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 + F+ +E G+P D T G +D +Q + +L I +G +GA+L GG Sbjct: 312 RSIKDRFLPMVIEALGTWKPGNPLDPATNVGALVDTQQMNTVLSYIAAGHTDGARLVAGG 371 Query: 384 SAM--EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTA 441 + E G +++PT+F V + MRIA+EEIFGPV +L F + EE I+ AN T YGL A Sbjct: 372 KQILQETGGTYVEPTIFDGVNNAMRIAQEEIFGPVLSVLTFDTAEEAIQIANDTPYGLAA 431 Query: 442 AVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 AV+T NL KA A AL +G+VW+N Y+ APFGGFK SGNGR+ +A +YTE+K Sbjct: 432 AVWTANLSKAHLTARALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKSLHAFDKYTELK 491 Query: 502 TVTIKL 507 + IKL Sbjct: 492 STWIKL 497 >2D4E-A nrPDB Length = 515 Score = 563 bits (1451), Expect = e-161, Method: Composition-based stats. Identities = 202/492 (41%), Positives = 302/492 (61%), Gaps = 15/492 (3%) Query: 25 RNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQR 84 R L+ + FI E+ S+SG+ F + +P+T E + G + +VD+A +AA AFQR Sbjct: 20 RRLKERPALHFIAGEFVPSESGETFPSLDPATNEVLGVAARGGEREVDRAAKAAHEAFQR 79 Query: 85 GSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYF 144 W R A R R L ++A+L+E+ LA +E +D G+ + ++ Sbjct: 80 ---WSRTKAKERKRYLLRIAELIEKHADELAVMECLDAGQVLRIVR-AQVARAAENFAFY 135 Query: 145 AGWADK-IQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 A +A+ ++ +T P D + + +T P G G ITPWN PL++ W++APAL GNT+VL Sbjct: 136 AEYAEHAMEDRTFPVDRDWLYYTVRVPAGPVGIITPWNAPLMLSTWRIAPALAFGNTVVL 195 Query: 204 KPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGK 263 KPAE +P TA L ++KEA PPGV N+V GFG GAA+ +HP + + TG TE GK Sbjct: 196 KPAEWSPFTATKLAEILKEADLPPGVFNLVQGFGEEAGAALVAHPLVPLLTLTGETETGK 255 Query: 264 LVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 +V A+ +LKR++ ELGGK+P +V ADADL+ A++ +F G+ CTA+SR+ VE Sbjct: 256 IVMRNAA-DHLKRLSPELGGKSPALVFADADLERALDAVVFQIFSFNGERCTASSRLLVE 314 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 E+++ +FV + VE A+ VG P D +TE GP I + ++L +E+GK+EGA+L GG Sbjct: 315 EKIFEDFVGKVVERARAIRVGHPLDPETEVGPLIHPEHLQRVLGYVEAGKREGARLLVGG 374 Query: 384 SAME--------DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANST 435 + +G ++ PTVF ++M+IA+EEIFGPV + FK EE +++AN T Sbjct: 375 ERAKTSFRGEDLSRGNYLLPTVFVG-ENHMKIAQEEIFGPVLVAIPFKDEEEALRKANDT 433 Query: 436 DYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALA 495 YGL A VFT++L++A +LA LE+G V++N +N + PFGG K SG+ RE G YAL Sbjct: 434 KYGLAAYVFTRDLERAHRLALELEAGMVYLNSHNVRHLPTPFGGVKGSGDRREGGTYALD 493 Query: 496 EYTEVKTVTIKL 507 YT++KT+ + L Sbjct: 494 FYTDLKTIALPL 505 >3R31-A nrPDB Length = 517 Score = 555 bits (1431), Expect = e-158, Method: Composition-based stats. Identities = 189/480 (39%), Positives = 278/480 (57%), Gaps = 10/480 (2%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 FI+ ++ E +G F + P+T E I ++ V++A+ +A+ A + W + Sbjct: 17 HFIDGDYVEDNTGTPFESIFPATGEMIAKLHAATPAIVERAIASAKRAQKE---WAAMSP 73 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD-KIQ 152 ++RGR+L + AD++ L+ LET+DTGKP D +F G A + Sbjct: 74 MARGRILKRAADIMRERNDALSTLETLDTGKPIQETIVADPTSGADAFEFFGGIAPSALN 133 Query: 153 GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 G IP +T+ P+GVC I WN+P + WK APAL GN MV KP+E TPL Sbjct: 134 GDYIPL-GGDFAYTKRVPLGVCVGIGAWNYPQQIACWKAAPALVAGNAMVFKPSENTPLG 192 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 AL + ++ EAG P G+ N++ G G + +HP + K++ TGS G+ V AA+ Sbjct: 193 ALKIAEILIEAGLPKGLFNVIQGD-RDTGPLLVNHPDVAKVSLTGSVPTGRKVAAAAA-G 250 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 +LK VT+ELGGK+P IV DAD++ AV A G F++ GQ C+ +RVFV+++ + F+ Sbjct: 251 HLKHVTMELGGKSPMIVFDDADIESAVGGAMLGNFYSSGQVCSNGTRVFVQKKAKARFLE 310 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS---AMEDK 389 + +GDP D T GP + + Q +K+L IE GK EGA L GG + + Sbjct: 311 NLKRRTEAMILGDPLDYATHLGPLVSKAQQEKVLSYIEKGKAEGATLITGGGIPNNVAGE 370 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 G +++PTVF++VTD+M IA+EEIFGPV +L F +EV+ RAN+T++GL VFT +L Sbjct: 371 GAYVQPTVFADVTDDMTIAREEIFGPVMCVLDFDDEDEVLARANATEFGLAGGVFTADLA 430 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGD 509 +A ++ LE+GT+WIN YN + PFGG K SG GRE AL Y+E+KTV + G Sbjct: 431 RAHRVVDGLEAGTLWINTYNLCPVEIPFGGSKQSGFGRENSAAALEHYSELKTVYVSTGK 490 >4V6H-A nrPDB Length = 484 Score = 546 bits (1407), Expect = e-155, Method: Composition-based stats. Identities = 174/486 (35%), Positives = 258/486 (53%), Gaps = 6/486 (1%) Query: 21 PRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQV 80 P +++ + + +I EW + S F +P+T E + V + + A + Sbjct: 2 PGSMKDPSLLRHQAYIGGEWQAADSDATFEVFDPATGESLGTVPKMGAAE---TARAIEA 58 Query: 81 AFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT 140 A + WR A R +L + DLV + LA + T + GKP A ++ Sbjct: 59 AQAAWAGWRMKTAKERAAILRRWFDLVIANSDDLALILTTEQGKPLAEAKG-EIAYAASF 117 Query: 141 LRYFAGWADKIQGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGN 199 + +FA ++ G T+PT D N EPIGVC AITPWNFP M+ K+ PAL G Sbjct: 118 IEWFAEEGKRVAGDTLPTPDANKRIVVVKEPIGVCAAITPWNFPAAMIARKVGPALAAGC 177 Query: 200 TMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 +V+KPAE TP +AL + L + AG P GV+++V G +G I+S+P + K++FTGST Sbjct: 178 PIVVKPAESTPFSALAMAFLAERAGVPKGVLSVVIGDPKAIGTEITSNPIVRKLSFTGST 237 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319 VG+L+ ++ +K++TLELGG P IV DADLD AVE A + N GQ C +R Sbjct: 238 AVGRLLMAQSA-PTVKKLTLELGGNAPFIVFDDADLDAAVEGAIASKYRNNGQTCVCTNR 296 Query: 320 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL 379 FV E+VY F + K VG + GP I++ K+ I +GA L Sbjct: 297 FFVHERVYDAFADKLAAAVSKLKVGRGTESGATLGPLINEAAVKKVESHIADALAKGASL 356 Query: 380 ECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 GG F +PTV + V +M +AKEE FGP+ P+ +F S EE+++ AN T++GL Sbjct: 357 MTGGKRHALGHGFFEPTVLTGVKPDMDVAKEETFGPLAPLFRFASEEELVRLANDTEFGL 416 Query: 440 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTE 499 A ++++++ + ++A ALE G V IN APFGG K SG GRE Y + +Y Sbjct: 417 AAYLYSRDIGRVWRVAEALEYGMVGINTGLISNEVAPFGGVKQSGLGREGSHYGIDDYVV 476 Query: 500 VKTVTI 505 +K + + Sbjct: 477 IKYLCV 482 >5KLK-A nrPDB Length = 520 Score = 540 bits (1391), Expect = e-154, Method: Composition-based stats. Identities = 175/484 (36%), Positives = 264/484 (54%), Gaps = 15/484 (3%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 +I+ + S S FA NP + I +V E D V++AV AAQ A + PW +L Sbjct: 42 NYIDGNFVTSASS--FANINPVNGKLISDVFEADAKQVNEAVVAAQNALK--GPWGKLSV 97 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 R L+H++AD ++ A E DTG+P A +D+ I R FA A Sbjct: 98 QDRAALIHKIADGIQARFEEFVAAEVADTGRPVHQARTLDIPRAIANFRTFADLAKTSHT 157 Query: 154 KTIPTD----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 + +T +P+GV G I+PW+ PLL+ WK+APAL CGNT+V KP+E++ Sbjct: 158 DLFEMSTSDGSGALNYTVRKPLGVIGVISPWDLPLLLFTWKVAPALACGNTVVAKPSEES 217 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPT-VGAAISSHPQINKIAFTGSTEVGKLVKEA 268 P +A L ++ +AG PPGV N++ GFG G ++ HP I+ + FTG ++ G + +A Sbjct: 218 PSSATLLAEVMHDAGVPPGVFNLIHGFGKDSAGEFLTQHPGISALTFTGESKTGSTIMKA 277 Query: 269 ASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYS 328 + +K V+ ELGGKN +V ADADLD A+E + F N GQ C + RV+V ++ Sbjct: 278 VA-DGVKEVSFELGGKNAAVVFADADLDAAIEGVLRSSFTNSGQVCLCSERVYVHRSIFD 336 Query: 329 EFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME- 387 EFV A++ VG P GP I DK+L EGA + GG + Sbjct: 337 EFVSGLKVEAERLVVGYPDQDGVNMGPLISHGHRDKVLSYYRLAVDEGATVVTGGGVPKF 396 Query: 388 ----DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 D+G +++PT+++ ++D R EEIFGPV I F +EVI R N ++YGL A+ Sbjct: 397 NDERDQGAYVQPTIWTGLSDKARCVTEEIFGPVCHISPFDDEDEVINRVNDSNYGLACAI 456 Query: 444 FTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 +T NL +A +++ + G VW+N + + PFGG K+SG GRE G +++ Y+++ + Sbjct: 457 WTTNLSRAHRVSRQIHVGLVWVNTWYLRDLRTPFGGVKLSGLGREGGRFSMDFYSDIANI 516 Query: 504 TIKL 507 IK+ Sbjct: 517 CIKI 520 >5J77-A nrPDB Length = 508 Score = 539 bits (1388), Expect = e-153, Method: Composition-based stats. Identities = 169/485 (34%), Positives = 270/485 (55%), Gaps = 13/485 (2%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 TK++I+ +W S SGK +P T + I +E + DVD+A++AA+ AF W L Sbjct: 3 TKLYIDGQWVNSSSGKTVDKYSPVTGQVIGRMEAATRDDVDRAIDAAEDAFW---AWNDL 59 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 ++ R +++++ +L+E++RA L + + GKP A +++G I ++Y+A WA K+ Sbjct: 60 GSVERSKIIYRAKELIEKNRAELENIIMEENGKPVKEAK-EEVDGVIDQIQYYAEWARKL 118 Query: 152 QGKTIP-TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 G+ + T + F P G+ A+TPWNFP M+ KLAPAL GNT+VLKP+ TP Sbjct: 119 NGEVVEGTSSHRKIFQYKVPYGIVVALTPWNFPAGMVARKLAPALLTGNTVVLKPSSDTP 178 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 +A ++ EAG P GV+N + G G +G I H ++N I TGST G+ + + AS Sbjct: 179 GSAEWIVRKFVEAGVPKGVLNFITGRGSEIGDYIVEHKKVNLITMTGSTATGQRIMQKAS 238 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEF 330 +N+ ++ LELGGK P +V DAD+D A++ ++N GQ C AA R++V E +Y F Sbjct: 239 -ANMAKLILELGGKAPFMVWKDADMDNALKTLLWAKYWNAGQSCIAAERLYVHEDIYDTF 297 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME--- 387 + R VE ++K +GDP + + GP I++ E++E K+ GAK+ GGS Sbjct: 298 MSRFVELSRKLALGDPKN--ADMGPLINKGALQATSEIVEEAKESGAKILFGGSQPSLSG 355 Query: 388 --DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 G F PT+ +I +EEIF PV K S+EE+ AN YGL + +FT Sbjct: 356 PYRNGYFFLPTIIGNADQKSKIFQEEIFAPVIGARKISSVEEMYDLANDNKYGLASYLFT 415 Query: 446 KNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 K+ + + + + G +++N +Q GF+M+G E +Y ++EY ++K + + Sbjct: 416 KDPNIIFEASERIRFGELYVNMPGPEASQGYHTGFRMTGQAGEGSKYGISEYLKLKNIYV 475 Query: 506 KLGDK 510 K Sbjct: 476 DYSGK 480 >3TY7-A nrPDB Length = 478 Score = 534 bits (1375), Expect = e-152, Method: Composition-based stats. Identities = 179/477 (37%), Positives = 257/477 (53%), Gaps = 12/477 (2%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 +TK +IN EW ES S + NP+T E I +V +G+K DVDKAVEAA + +R Sbjct: 6 DYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADVDKAVEAADDVYLE---FR 62 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R LL ++ E + + T + G P + + + + D Sbjct: 63 HTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERVHYQMGLNHFVAARDALD 122 Query: 150 KIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 + + DD E IGV G ITPWNFP KLA A G+ +VLKP+E+T Sbjct: 123 NYEFEERRGDD----LVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVLKPSEET 178 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 P A+ L + + G P GV N+V G G VG +S HP++ ++FTGS G + E A Sbjct: 179 PFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRMMSFTGSGPTGSKIMEKA 238 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 ++ + K+V+LELGGK+P IV D D+ A + V N GQ CTA +RV V ++ Sbjct: 239 AK-DFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTGQVCTAGTRVLVPNKIKDA 297 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME-- 387 F+ E + VG+P + T+ GP I +KQFD++ I G +EGA+L GG Sbjct: 298 FLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYINKGIEEGAELFYGGPGKPEG 357 Query: 388 -DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 +KG F +PT+F V + M IA+EEIFGPV ++ + ++E I+ AN T YGL V K Sbjct: 358 LEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYNDLDEAIQIANDTKYGLAGYVIGK 417 Query: 447 NLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 + + K+A ++E+GTV IN PFGG+K SG GRE G+Y + E+ EVK++ Sbjct: 418 DKETLHKVARSIEAGTVEINEA-GRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSI 473 >1WNB-A nrPDB Length = 495 Score = 533 bits (1374), Expect = e-152, Method: Composition-based stats. Identities = 169/478 (35%), Positives = 262/478 (54%), Gaps = 8/478 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 K+ IN E + G+K NP+T + + E+ E VD AV AA + W + Sbjct: 24 HKLLINGELVSGE-GEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADA---AFAEWGQT 79 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R L +LAD++E + A LE+ + GKP AF ++ + R+FAG A + Sbjct: 80 TPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCL 139 Query: 152 QGKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 G + R +P+GV +I PWN+PL+M WKLAPAL GN +VLKP+E TP Sbjct: 140 NGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITP 199 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 LTAL L L K+ FP GVVNI+ G G TVG ++ HP++ ++ TGS G+ + + Sbjct: 200 LTALKLAELAKDI-FPAGVVNILFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTA 258 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEF 330 S++KR +ELGGK P IV DAD++ VE ++N GQ CTAA R++ ++ +Y Sbjct: 259 -SSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTL 317 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEG-AKLECGGSAMEDK 389 V + G P D TE GP +++ + +E K G K+ GG + Sbjct: 318 VEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVGKAVEEAKATGHIKVITGGEKRKGN 377 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 G + PT+ + + I ++E+FGPV + F + E+V+ AN + YGL ++V+TK++ Sbjct: 378 GYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNEEQVVNWANDSQYGLASSVWTKDVG 437 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 +A ++++ L+ G W+N + L ++ P GG K+SG G+++ Y L +YT V+ V +K Sbjct: 438 RAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH 495 >6C43-A nrPDB Length = 477 Score = 529 bits (1364), Expect = e-151, Method: Composition-based stats. Identities = 167/477 (35%), Positives = 259/477 (54%), Gaps = 8/477 (1%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 ++ IN + + G++ + NP+T E I E+ E VD AV+AA AF + W + Sbjct: 7 QLLINGVLVDGE-GERQSVYNPATGEVILEIAEASPAQVDAAVQAADNAF---AEWGQTT 62 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 +R L +LAD +E++ A LE+ + GKP ++ + R+FAG A + Sbjct: 63 PKARAECLLKLADSIEQNALEFARLESQNCGKPLHCVINDEIPAIVDVFRFFAGAARCLS 122 Query: 153 GKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G + R +PIGV +I PWN+PL+M WKLAPAL GN +V+KP+E TPL Sbjct: 123 GLAAGEYLEGHTSMIRRDPIGVVASIAPWNYPLMMAAWKLAPALAAGNCVVIKPSEITPL 182 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 TAL L L K+ FPPGV+N++ G G TVG ++ H ++ ++ TGS G+ + + Sbjct: 183 TALKLAVLAKDI-FPPGVLNVLFGRGQTVGDVLTGHEKVRMVSLTGSIATGEHILRHTA- 240 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 +KR +ELGGK P IV DADLD + F+N GQ CTAA R++ + +Y V Sbjct: 241 PAIKRTHMELGGKAPVIVFDDADLDAVAQGVRTFGFYNAGQDCTAACRIYAQRGIYDALV 300 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKK-EGAKLECGGSAMEDKG 390 + +G P D TE GP ++ +E K ++ GGS E KG Sbjct: 301 EKLGNAVSSLKMGAPEDESTELGPLSSLAHLKRVTAAVEEAKALSHIRVITGGSQTEGKG 360 Query: 391 LFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDK 450 + PT+ ++ I + E+FGPV I F ++V++ AN + YGL ++V+T+++ + Sbjct: 361 YYFAPTLLADAKQEDAIVQREVFGPVVSITVFDDEDQVLRWANDSRYGLASSVWTQDVGR 420 Query: 451 ALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 A +L++ L+ G WIN + L ++ P GG K SG G+++ Y L +YT V+ + +K Sbjct: 421 AHRLSARLQYGCTWINTHFMLVSEMPHGGQKQSGYGKDMSLYGLEDYTLVRHIMVKH 477 >3EK1-A nrPDB Length = 504 Score = 528 bits (1360), Expect = e-150, Method: Composition-based stats. Identities = 181/496 (36%), Positives = 269/496 (54%), Gaps = 8/496 (1%) Query: 10 NGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKP 69 + + P +++ + ++ +N W ++ G NP+ I V Sbjct: 11 TLEAQTQGPGSMLALKDPSLLKSQCLVNGRWIDAADGTTIKVTNPADGSVIGTVPSLSVA 70 Query: 70 DVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHA 129 + +A++A+ A S W A R +L + DL+ + +A + T + GKP A Sbjct: 71 TIKEAIDASAKAL---SGWAAKTAKERAGILRKWFDLIIANADDIALIMTSEQGKPLAEA 127 Query: 130 FFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR-HEPIGVCGAITPWNFPLLMLV 188 ++ + +FA A ++ G TIP N T +P+GV AITPWNFP M+ Sbjct: 128 RG-EVLYAASFIEWFAEEAKRVYGDTIPAPQNGQRLTVIRQPVGVTAAITPWNFPAAMIT 186 Query: 189 WKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHP 248 K APAL G TM+++PA+ TPLTAL LG L ++AG P GV+ IV G +GA ++S+ Sbjct: 187 RKAAPALAAGCTMIVRPADLTPLTALALGVLAEKAGIPAGVLQIVTGKAREIGAELTSND 246 Query: 249 QINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFF 308 + K++FTGSTEVG+L+ + +KR++LELGG P IV DADLD AV+ A + Sbjct: 247 TVRKLSFTGSTEVGRLLMAQCA-PTIKRISLELGGNAPFIVFDDADLDAAVDGAMVSKYR 305 Query: 309 NQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILEL 368 N GQ C A+R++V+ VY +F + K+ VG+ + GP I++K K+ Sbjct: 306 NAGQTCVCANRIYVQRGVYDKFAEKLAAKVKELKVGNGTEPGVVIGPMIEEKAITKVKAH 365 Query: 369 IESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEV 428 IE +GAKL GG E GLF +P + + VT +M +AKEE FGP+ P+ F + EEV Sbjct: 366 IEDAVSKGAKLITGGK--ELGGLFFEPGILTGVTSDMLVAKEETFGPLAPLFAFDTEEEV 423 Query: 429 IKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRE 488 I +AN T +GL A +T+N +A++++ ALE G V N APFGG K SG GRE Sbjct: 424 IAQANDTIFGLAAYFYTENFSRAIRVSEALEYGMVGHNTGLISNEVAPFGGVKQSGLGRE 483 Query: 489 LGEYALAEYTEVKTVT 504 +Y + EY E K + Sbjct: 484 GSKYGIEEYLETKYIC 499 >4U3W-A nrPDB Length = 505 Score = 522 bits (1344), Expect = e-148, Method: Composition-based stats. Identities = 179/489 (36%), Positives = 261/489 (53%), Gaps = 15/489 (3%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 + + +IN E+ SG F +P ++ +V E D VD AV+AA A + G WR Sbjct: 22 QLLRHYINGEFV--ASGTTFPNLSPVDGRKLADVCEADAALVDSAVQAAHAAQKAG--WR 77 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R LH++AD +E A E DTG+P A +D+ I R FA Sbjct: 78 DTTPAQRAAWLHKIADGIEARFDEFVAAEVADTGRPVAQARTLDIARGIANFRTFADLVR 137 Query: 150 KIQGKTIPTD----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKP 205 G+ T ++ + +P+GV G I+PWN PLL+ WK+APAL GN +V KP Sbjct: 138 TASGEYFETHAADGSELINYVTRKPLGVIGIISPWNLPLLLFTWKVAPALAMGNCVVAKP 197 Query: 206 AEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGP-TVGAAISSHPQINKIAFTGSTEVGKL 264 +E+TP +A L ++ + G PPGV N++ G G G ++ HP I+ I FTG + G Sbjct: 198 SEETPSSATLLAEVMHDVGLPPGVFNLIHGHGQNAAGEFLTRHPDISAITFTGESRTGST 257 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + +A + +K V+ ELGGKN +V ADAD D AV + F N GQ C + RV+VE Sbjct: 258 IMKAVA-DGVKEVSFELGGKNAAVVFADADFDAAVAGVLRSSFTNAGQVCLCSERVYVER 316 Query: 325 QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS 384 ++ FV E A+ VG P D T GP I + DK+L +EGA + GG Sbjct: 317 PIFERFVAALKEQAQALRVGAPEDPATTMGPLISRGHRDKVLSYFRLAVEEGATVVTGGG 376 Query: 385 AME-----DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 A D G F+ PT+++ + D+ R +EEIFGPV I F EV+KR N + YGL Sbjct: 377 APSFGDARDDGAFVMPTIWTGLPDSARCVREEIFGPVCHIAPFDDEAEVVKRVNDSAYGL 436 Query: 440 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTE 499 A+++T L + ++A +E+G VW+N + + PFGG K+SG GRE G ++L Y+E Sbjct: 437 AASIWTTQLARGHRVAKQIETGIVWVNAWFVRDLRTPFGGTKLSGLGREGGRHSLDFYSE 496 Query: 500 VKTVTIKLG 508 + V +++ Sbjct: 497 LTNVCVRIA 505 >4LIH-A nrPDB Length = 504 Score = 521 bits (1342), Expect = e-148, Method: Composition-based stats. Identities = 198/480 (41%), Positives = 290/480 (60%), Gaps = 8/480 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 + FI+ ++ G+ F +P + +V + + DV+ AV AA+ AF G W L Sbjct: 28 GRAFIDGASRDAHGGRTFDCVSPIDGRVLAKVADCGEADVNAAVAAARRAFDAG-VWAGL 86 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 + +R +L + A L+ L+ LET+D GKP +D+ G + +FA DK+ Sbjct: 87 NPRARKAVLLRWAALMREHLDELSLLETLDAGKPIGDTTTVDVPGAAYCVEWFAEAIDKV 146 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G+ P D ++V EP+GV A+ PWNFP+LM WK PAL GN++VLKP+E++PL Sbjct: 147 GGEVAPADHHLVGLVTREPVGVVAAVVPWNFPILMAAWKFGPALAAGNSVVLKPSEKSPL 206 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 TA+ + L EAG P GV N+VPG G G ++ H ++ IAFTGST VGKL+ + A++ Sbjct: 207 TAIRVAQLAFEAGIPAGVFNVVPGAG-EPGKLLALHRDVDCIAFTGSTAVGKLIMQYAAQ 265 Query: 272 SNLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEF 330 SNLKR LELGGK+P IV D DLD A + A +F+N G+ CTA SR+ V + F Sbjct: 266 SNLKRAWLELGGKSPNIVLPDCPDLDRAAQTAAGAIFYNMGEMCTAGSRLLVHRDIKDAF 325 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM--ED 388 + + V A+ G+P D G +D Q +++L IE+G+ EG +L GG+ + E Sbjct: 326 IEKLVAAARAYVPGNPLDPSVSMGAIVDGIQLERVLGYIEAGRGEG-RLVTGGARVNAET 384 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 G +++PTVF EV + +IA+EEIFGPV ++ F ++E ++ AN T+YGL AAV+T NL Sbjct: 385 GGFYVEPTVF-EVKPDAKIAREEIFGPVLSVIVFDDVDEAVRIANDTEYGLAAAVWTSNL 443 Query: 449 DKALKLASALESGTVWINCYN-ALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKL 507 A ++ L +GTVW+NCY+ PFGG+K SGNGR+ +AL +YTE+K+ I+L Sbjct: 444 TTAHDVSRRLRAGTVWVNCYDEGGDMNFPFGGYKQSGNGRDKSLHALEKYTELKSTLIRL 503 >3U4J-A nrPDB Length = 528 Score = 520 bits (1341), Expect = e-148, Method: Composition-based stats. Identities = 188/498 (37%), Positives = 286/498 (57%), Gaps = 7/498 (1%) Query: 18 PALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPST-REQICEVEEGDKPDVDKAVE 76 P P ++ ++ ++ ++ + ++ SG +P E + E DV KAV Sbjct: 10 PDSNDPRLRIKSRY-QMLVDGKSVDAASGSTIDRVSPGHAGEVVGTWPEASADDVRKAVA 68 Query: 77 AAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEG 136 AA+ AF G PW R+ R RL+ ++ADL+ + LA +E+++ GKP A ++ Sbjct: 69 AARKAFDAG-PWPRMSGAERSRLMFKVADLILARQEELALIESLEVGKPIAQARG-EIGF 126 Query: 137 CIRTLRYFAGWADKIQGKTIP-TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPAL 195 C Y AG A ++G+T D+ + EP+GV G ITPWNFP ++ ++ A+ Sbjct: 127 CADLWSYAAGQARALEGQTHNNIGDDRLGLVLREPVGVVGIITPWNFPFIIASERVPWAI 186 Query: 196 CCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAF 255 G T+VLKP+E T T++ L L +EAG P GV N+V G+G G ++ P ++ +AF Sbjct: 187 GSGCTVVLKPSEFTSGTSIRLAELAREAGIPDGVFNVVTGYGDPAGQVLAEDPNVDMVAF 246 Query: 256 TGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCT 315 TGS VG + E A+R+ +KRV LELGGK P IV ADADLD A + GV+ N GQCC Sbjct: 247 TGSVRVGTKLGEIAART-VKRVGLELGGKGPQIVFADADLDAAADGIAYGVYHNAGQCCI 305 Query: 316 AASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE 375 + SR+ V+E + + R ++ ++K GDP + +T+ G I + +K+ + +G Sbjct: 306 SGSRLLVQEGIRDALMERLLDISRKVAFGDPLNERTKIGAMISEAHAEKVHSYVTAGITS 365 Query: 376 GAKLECGGSAM-EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANS 434 GA+L GG + + GL+ PTVF+ VT +M IA+EEIFGPV L FK+ +E + AN+ Sbjct: 366 GAELLLGGERIGREAGLYYAPTVFAGVTPDMSIAREEIFGPVLSTLTFKTADEAVALANA 425 Query: 435 TDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYAL 494 T++GL+A+V++ NL+ AL+ + +G WIN + P GG+K SG GRELG Y Sbjct: 426 TEFGLSASVWSTNLETALQTIRRIRAGRCWINSVIDGTPELPIGGYKKSGLGRELGRYGF 485 Query: 495 AEYTEVKTVTIKLGDKNP 512 EY++ K V + LG P Sbjct: 486 DEYSQFKGVHVTLGRPAP 503 >2HG2-A nrPDB Length = 479 Score = 520 bits (1339), Expect = e-148, Method: Composition-based stats. Identities = 156/475 (32%), Positives = 255/475 (53%), Gaps = 7/475 (1%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 ++I+ ++ + NP+T I + +G D KA++AA+ A W L A Sbjct: 9 MYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERAQ---PEWEALPA 65 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 + R L +++ + + ++AL + GK +++ + Y A WA + +G Sbjct: 66 IERASWLRKISAGIRERASEISALIVEEGGK-IQQLAEVEVAFTADYIDYMAEWARRYEG 124 Query: 154 KTIPTDDNVVCFTR-HEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 + I +D +GV I PWNFP ++ K+APAL GNT+V+KP+E TP Sbjct: 125 EIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIARKMAPALLTGNTIVIKPSEFTPNN 184 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 A+ ++ E G P GV N+V G G TVG ++ +P++ ++ TGS G+ + A++ Sbjct: 185 AIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMATAAK- 243 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 N+ +V LELGGK P IV DADL+LAV+ N GQ C A RV+V++ +Y +FV Sbjct: 244 NITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQFVN 303 Query: 333 RSVEYAKKRPVGDPFDV-KTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 R E + G+P + GP I+ +++ + + +EGA++ GG A+E KG Sbjct: 304 RLGEAMQAVQFGNPAERNDIAMGPLINAAALERVEQKVARAVEEGARVAFGGKAVEGKGY 363 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 + PT+ +V M I EE FGPV P++ F ++E+ I AN +DYGLT++++T+NL+ A Sbjct: 364 YYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDAISMANDSDYGLTSSIYTQNLNVA 423 Query: 452 LKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 +K L+ G +IN N Q G++ SG G G++ L EY + + V ++ Sbjct: 424 MKAIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLHEYLQTQVVYLQ 478 >3I44-A nrPDB Length = 497 Score = 519 bits (1338), Expect = e-148, Method: Composition-based stats. Identities = 168/476 (35%), Positives = 266/476 (55%), Gaps = 9/476 (1%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 K +IN W + + +PST E + G D DKA+ AA+ AFQ W+ Sbjct: 26 RKFYINGLWDDPSTPHDLYVIDPSTEEACAVISLGSTRDADKAINAAKKAFQ---TWKTT 82 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R + ++ ++ E+ + +A +M+ G P A +R F + Sbjct: 83 SPHERLGFVEKILEIYEKRSSDMAKTISMEMGAPIDMALNAQTATGSSHIRNFIKAYKEF 142 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 + + N ++ IGV G ITPWN+P+ + K+ PAL G TMVLKP+E PL Sbjct: 143 SFQEALIEGNEQAILHYDAIGVVGLITPWNWPMNQVTLKVIPALLAGCTMVLKPSEIAPL 202 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 +A+ ++ EA P GV N++ G G VG+ +S+HP + I+FTGST GK + + AS Sbjct: 203 SAMLFAEILDEAALPSGVFNLINGDGANVGSYLSAHPDLEMISFTGSTRAGKDISKNASN 262 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 + LKRV LELGGK I+ ADAD+D A++ + F+N GQ C A +R+ VE+ +Y + + Sbjct: 263 T-LKRVCLELGGKGANIIFADADID-ALQRGVRHCFYNSGQSCNAPTRMLVEQAIYDKAI 320 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME---D 388 + + + A+K VG GP + ++Q+DKI +LI+SG EGA L GG+ + + Sbjct: 321 KTAKDIAEKTQVGPGHQTGNHIGPVVSKEQYDKIQDLIQSGIDEGATLVTGGTGLPMGME 380 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 +G +++PTVF++V +MRI +EEIFGPV +L F + +E + AN T+YGLT + +++ Sbjct: 381 RGYYVRPTVFADVKPHMRIFREEIFGPVLSLLPFNTEDEAVTLANDTEYGLTNYIQSQDR 440 Query: 449 DKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 K ++A+ + SG V +N + L + FGG K SG RE G + + E+ + K ++ Sbjct: 441 SKCRRIAAQVRSGMVEVNG-HELPGGSYFGGVKFSGRAREGGLWGIKEFLDTKAIS 495 >3K2W-A nrPDB Length = 497 Score = 517 bits (1332), Expect = e-147, Method: Composition-based stats. Identities = 172/488 (35%), Positives = 253/488 (51%), Gaps = 10/488 (2%) Query: 24 IRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQ 83 +++L K FI ++ S +PST + I E+ G K D + A+E AQ A + Sbjct: 5 VQDLHFKNKVNFIGGQYVPSNESDTIDILSPSTGKVIGEIPAGCKADAENALEVAQAAQK 64 Query: 84 RGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 + L A +R +L A+ + ++ LA + + GK A ++++ + Y Sbjct: 65 AWAK---LTARTRQNMLRTFANKIRENKHILAPMLVAEQGKLLSVAE-MEVDVTATFIDY 120 Query: 144 FAGWADKIQGKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMV 202 A I+G +P+D + + P GV IT WNFPL + K+ PAL GNTMV Sbjct: 121 GCDNALTIEGDILPSDNQDEKIYIHKVPRGVVVGITAWNFPLALAGRKIGPALITGNTMV 180 Query: 203 LKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG 262 LKP ++TPL LG + KEAG P GV+N++ G G VG + P I TGST G Sbjct: 181 LKPTQETPLATTELGRIAKEAGLPDGVLNVINGTGSVVGQTLCESPITKMITMTGSTVAG 240 Query: 263 KLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFV 322 K + + ++ + V LELGGK P +V DADLD A E A G F N GQ CT R++V Sbjct: 241 KQIYKTSAEY-MTPVMLELGGKAPMVVMDDADLDKAAEDALWGRFANCGQVCTCVERLYV 299 Query: 323 EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECG 382 VY EF+ + + K VGDP D ++ GP+ +Q++ D I ++ K+GA + G Sbjct: 300 HASVYDEFMAKFLPLVKGLKVGDPMDADSQMGPKCNQREIDNIDHIVHEAIKQGATVATG 359 Query: 383 GSAME----DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG 438 G + G + +PTV +V + + EE FGP+ PI+K S+E+ I+ N + YG Sbjct: 360 GKTATVEGFEGGCWYEPTVLVDVKQDNIVVHEETFGPILPIVKVSSMEQAIEFCNDSIYG 419 Query: 439 LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYT 498 L+A V T++ + S LE G V+IN Q G+K SG G E G++ L +Y Sbjct: 420 LSAYVHTQSFANINQAISDLEVGEVYINRGMGEQHQGFHNGWKQSGFGGEDGKFGLEQYL 479 Query: 499 EVKTVTIK 506 E KTV I Sbjct: 480 EKKTVYIN 487 >4F3X-A nrPDB Length = 498 Score = 517 bits (1332), Expect = e-147, Method: Composition-based stats. Identities = 176/482 (36%), Positives = 266/482 (55%), Gaps = 14/482 (2%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 T++ I + + E+ + + NP T I ++ E +D AV+AA+ AF W + Sbjct: 26 TQLLIGSRF-EAGTEAEEHILNPRTGAGIIDLAEASHAQIDAAVDAAERAF---VGWSQT 81 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R L ++AD +E++ AALE ++ GKP +L I R+FAG + Sbjct: 82 TPAERSNALLKIADAIEKEADEFAALEALNCGKPINAVKNDELPAIIDCWRFFAGAVRNL 141 Query: 152 Q----GKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 G+ +P R +PIG+ G+I PWN+PL+M+ WKLAPA+ GNT+V KP+E Sbjct: 142 HAPAAGEYLP---GHTSMIRRDPIGIVGSIAPWNYPLMMMAWKLAPAIGGGNTVVFKPSE 198 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 QTPLTAL L LI + P GVVN++ G G TVG A+ +HP++ ++ TG GK V Sbjct: 199 QTPLTALKLARLIADI-LPEGVVNVITGRGETVGNALINHPKVGMVSITGDIATGKKVLA 257 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 AA+++ +KR LELGGK P IV DADL+ V ++N GQ CTAA R++ E +Y Sbjct: 258 AAAKT-VKRTHLELGGKAPVIVYGDADLEAVVNGIRTFGYYNAGQDCTAACRIYAEAGIY 316 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE-GAKLECGGSAM 386 + V D + E GP I ++Q D++ +E + ++ GG Sbjct: 317 EKLVADLTSAVSTIRYNLDDDTENEIGPLISRRQRDRVASFVERAADQKHIEITTGGRTG 376 Query: 387 EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 D+G F +PTV + T I + E+FGPV + +F ++ + AN +DYGL ++V+TK Sbjct: 377 SDEGFFFQPTVVAGATQEDEIVRREVFGPVVSVTRFTGKDDAVAWANDSDYGLASSVWTK 436 Query: 447 NLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 ++ KA++ AS L+ G WIN + L + P GG K SG G+++ YAL +YT V+ + I Sbjct: 437 DISKAMRAASRLQYGCTWINTHFMLTNEMPHGGIKQSGYGKDMSVYALEDYTAVRHIMIN 496 Query: 507 LG 508 G Sbjct: 497 HG 498 >3QAN-A nrPDB Length = 538 Score = 512 bits (1319), Expect = e-145, Method: Composition-based stats. Identities = 176/520 (33%), Positives = 268/520 (51%), Gaps = 20/520 (3%) Query: 5 NGAVENGQPDRKPPALPRPIRNLEVKFTKIF---INNEWHESKSGKKFATCNPSTREQ-I 60 + + + A + +E + K + IN E + K + NP+ ++Q + Sbjct: 8 HEPFTDFTVEANRKAFEEALGLVEKELGKEYPLIINGERV--TTEDKIQSWNPARKDQLV 65 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 120 V + ++ +KA+++A AFQ WR ++ R +L + A ++ R + +A Sbjct: 66 GSVSKANQDLAEKAIQSADEAFQ---TWRNVNPEERANILVKAAAIIRRRKHEFSAWLVH 122 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ-GKTIPTDDNVVCFTRHEPIGVCGAITP 179 + GKP+ A D I L Y+A ++ GK I + + P+GV I+P Sbjct: 123 EAGKPWKEAD-ADTAEAIDFLEYYARQMIELNRGKEILSRPGEQNRYFYTPMGVTVTISP 181 Query: 180 WNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPT 239 WNF L ++V + GNT+VLKPA TP+ A ++++AG P GV+N VPG G Sbjct: 182 WNFALAIMVGTAVAPIVTGNTVVLKPASTTPVVAAKFVEVLEDAGLPKGVINYVPGSGAE 241 Query: 240 VGAAISSHPQINKIAFTGSTEVGKLVKEAAS-----RSNLKRVTLELGGKNPCIVCADAD 294 VG + HP+ + I FTGS +VG + E A+ +++LKRV +E+GGK+ +V DAD Sbjct: 242 VGDYLVDHPKTSLITFTGSKDVGVRLYERAAVVRPGQNHLKRVIVEMGGKDTVVVDRDAD 301 Query: 295 LDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQG 354 LDLA E F GQ C+A SR + + VY E + ++V AK VGDP + G Sbjct: 302 LDLAAESILVSAFGFSGQKCSAGSRAVIHKDVYDEVLEKTVALAKNLTVGDPTNRDNYMG 361 Query: 355 PQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFG 414 P ID+K F+KI+ IE GKKEG +L GG G FI+PT+ +++ I +EEIFG Sbjct: 362 PVIDEKAFEKIMSYIEIGKKEG-RLMTGGEGDSSTGFFIQPTIIADLDPEAVIMQEEIFG 420 Query: 415 PVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWI--NCYNALY 472 PV K + ++ AN+T+YGLT AV T+N + G ++ NC A+ Sbjct: 421 PVVAFSKANDFDHALEIANNTEYGLTGAVITRNRAHIEQAKREFHVGNLYFNRNCTGAIV 480 Query: 473 AQAPFGGFKMSGNGRE-LGEYALAEYTEVKTVTIKLGDKN 511 PFGGFKMSG + G LA + + KTV+ + Sbjct: 481 GYHPFGGFKMSGTDSKAGGPDYLALHMQAKTVSEMYAENL 520 >3B4W-A nrPDB Length = 495 Score = 505 bits (1302), Expect = e-143, Method: Composition-based stats. Identities = 180/487 (36%), Positives = 258/487 (52%), Gaps = 6/487 (1%) Query: 24 IRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQ 83 + + ++ K+FI +W + + P+T E + +V DVD AV AA+ AF Sbjct: 1 MSDSATEYDKLFIGGKWTKPSTSDVIEVRCPATGEYVGKVPMAAAADVDAAVAAARAAFD 60 Query: 84 RGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRY 143 G PW R ++ ++ + L +TG+P + G + + Y Sbjct: 61 NG-PWPSTPPHERAAVIAAAVKMLAERKDLFTKLLAAETGQPPTIIETMHWMGSMGAMNY 119 Query: 144 FAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 FAG ADK+ T EP+GV GAI WN PL + V K+APAL G T+VL Sbjct: 120 FAGAADKVTWTETRTGSYGQSIVSREPVGVVGAIVAWNVPLFLAVNKIAPALLAGCTIVL 179 Query: 204 KPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGK 263 KPA +TPLTA L + E G P GV+++VPG G G A++S+P I+ FTGS+ VG+ Sbjct: 180 KPAAETPLTANALAEVFAEVGLPEGVLSVVPG-GIETGQALTSNPDIDMFTFTGSSAVGR 238 Query: 264 LVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVE 323 V A+ LK TLELGGK+ I+ D DL A+ N GQ C +R+ Sbjct: 239 EVGRRAAEM-LKPCTLELGGKSAAIILEDVDLAAAIPMMVFSGVMNAGQGCVNQTRILAP 297 Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 Y E V + PVG P D + GP I +KQ ++ I G +EGA+L CGG Sbjct: 298 RSRYDEIVAAVTNFVTALPVGPPSDPAAQIGPLISEKQRTRVEGYIAKGIEEGARLVCGG 357 Query: 384 SAME--DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTA 441 E D G FI+PTVF++V + M IA+EEIFGPV I+ + + E+ I AN + YGL Sbjct: 358 GRPEGLDNGFFIQPTVFADVDNKMTIAQEEIFGPVLAIIPYDTEEDAIAIANDSVYGLAG 417 Query: 442 AVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVK 501 +V+T ++ K +K++ + +GT IN Y A +PFGG+K SG GRE G + +T+ K Sbjct: 418 SVWTTDVPKGIKISQQIRTGTYGINWY-AFDPGSPFGGYKNSGIGRENGPEGVEHFTQQK 476 Query: 502 TVTIKLG 508 +V + +G Sbjct: 477 SVLLPMG 483 >3RJL-A nrPDB Length = 538 Score = 505 bits (1300), Expect = e-143, Method: Composition-based stats. Identities = 172/514 (33%), Positives = 265/514 (51%), Gaps = 21/514 (4%) Query: 5 NGAVENGQPDRKPPALPRPIRNLE----VKFTKIFINNEWHESKSGKKFATCNPST-REQ 59 + N + A + + + + + I+ E ++ K + NP+ E Sbjct: 7 HEPFTNFGIEENRKAFEKALETVNNEWLGQSYPLVIDGE--RYETENKIVSINPANKEEV 64 Query: 60 ICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALET 119 + V + + +KA++AA AF+ WR D R +L + V R + +AL Sbjct: 65 VGTVSKATQDHAEKAIQAAAKAFE---TWRYTDPEERAAVLFRAVAKVRRKKHEFSALLV 121 Query: 120 MDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI-QGKTIPTDDNVVCFTRHEPIGVCGAIT 178 + GKP+ A D I + Y+A ++ +GK + + + + P GV I Sbjct: 122 KEAGKPWNEAD-ADTAEAIDFMEYYARQMIELAKGKPVNSREGERNQYVYTPTGVTVVIP 180 Query: 179 PWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGP 238 PWNF ++ + GNT+VLKPA P+ A +++E+G P GVVN VPG G Sbjct: 181 PWNFLFAIMAGTTVAPIVTGNTVVLKPASAAPVIAAKFVEVLEESGLPKGVVNFVPGSGA 240 Query: 239 TVGAAISSHPQINKIAFTGSTEVGKLVKEAASR-----SNLKRVTLELGGKNPCIVCADA 293 VG + HP+ + I FTGS EVG + E A++ ++LK+V E+GGK+ +V D Sbjct: 241 EVGDYLVDHPKTSIITFTGSREVGTRIFERAAKVQPGQTHLKQVIAEMGGKDTVVVDEDC 300 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQ 353 D++LA + F GQ C+A SR V E+VY E ++R +E + + VG+P Sbjct: 301 DIELAAQSIFTSAFGFAGQKCSAGSRAVVHEKVYDEVLKRVIEITESKKVGEPDSADVYM 360 Query: 354 GPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIF 413 GP IDQ F+KI++ IE GK+EG +L GG + KG FI+PT+F+++ R+ +EEIF Sbjct: 361 GPVIDQASFNKIMDYIEIGKEEG-RLVSGGKGDDSKGYFIEPTIFADLDPKARLMQEEIF 419 Query: 414 GPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWI--NCYNAL 471 GPV K S +E ++ AN+T+YGLT AV TKN D + G ++ NC A+ Sbjct: 420 GPVVAFSKVSSFDEALEVANNTEYGLTGAVITKNRDHINRAKQEFHVGNLYFNRNCTGAI 479 Query: 472 YAQAPFGGFKMSGNGRE-LGEYALAEYTEVKTVT 504 PFGGFKMSG + G LA + + KT++ Sbjct: 480 VGYHPFGGFKMSGTDSKAGGPDYLALHMQAKTIS 513 >5EUY-A nrPDB Length = 491 Score = 505 bits (1300), Expect = e-143, Method: Composition-based stats. Identities = 165/485 (34%), Positives = 265/485 (54%), Gaps = 11/485 (2%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRG 85 +L + +IN E+ E +G +P +I EV + D +A+++A F+ Sbjct: 3 DLNIMKVANYINGEFKEPSTGAFQVKTSPVDGSKIAEVPRSGREDAREAIDSA---FEAL 59 Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 W + A+ R L+++ ++ + + + T++ G + + ++ R ++ A Sbjct: 60 KAWANIPAIRRAEYLYKMLEVFRQMKEDFMKILTVEGGGTYRK-VWGEVVFTERLIQNAA 118 Query: 146 GWADKIQGKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 A QG+ + +D ++ + GV G ITPWN+PL + + K+A L GNT+V K Sbjct: 119 ELARHYQGRVLQSDSESTISVVFKRSKGVVGVITPWNYPLSISMKKIAHTLAVGNTVVYK 178 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKL 264 PA TP+T + ++ +AG P GV N+V G GP VG I +H ++ + FTG + G+ Sbjct: 179 PASDTPVTGWLIAQMVAKAGLPKGVFNLVIGPGPVVGEEIVTHKRVAHVTFTGESSTGRE 238 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + A+ LK VTLELGG +P I+ D D+D A A F+QGQ CT+A R+ V + Sbjct: 239 IAAKAA-GTLKTVTLELGGSDPLIILDDVDVDYAARLAVFASLFHQGQICTSAKRIIVHK 297 Query: 325 QVYSEFVRRSVEYAKKRPVGDPF-DVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 V +F+ R V Y K + DP D K + GP I+++Q + E ++ G +L GG Sbjct: 298 AVADKFIERYVHYVKMLRIDDPRKDEKVDLGPLINERQVALMKEFVDDAVSRGGRLLIGG 357 Query: 384 SAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAV 443 + G F +P +F +V N RI +EE+FGPV+PI+ ++ ++ ++ AN TDYGL+ AV Sbjct: 358 RSW---GNFFEPAIFVDVDRNFRIMREEVFGPVRPIVVVENDDQAVEVANDTDYGLSGAV 414 Query: 444 FTKNLDKALKLASALESGTVWINCYNAL-YAQAPFGGFKMSGNGRELGEYALAEYTEVKT 502 T N+++A ++A A+ESG IN L + PFGG K SG GRE GE++ E T + Sbjct: 415 LTNNVNRAFRIAEAVESGMFHINDVTFLEESHVPFGGIKASGVGREGGEWSFHETTYDRW 474 Query: 503 VTIKL 507 VT+ L Sbjct: 475 VTVTL 479 >1T90-A nrPDB Length = 486 Score = 503 bits (1295), Expect = e-143, Method: Composition-based stats. Identities = 166/488 (34%), Positives = 249/488 (51%), Gaps = 11/488 (2%) Query: 28 EVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSP 87 E++ K +IN EW ESK+ + NP+T+E +C+V K D+D A + A AF+ Sbjct: 2 EIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFK---T 58 Query: 88 WRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGW 147 W ++ R R+L L+ + + LA L T++ GK A ++ I + + AG Sbjct: 59 WSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALG-EVGRGIENVEFAAGA 117 Query: 148 ADKIQGKTIPT-DDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 206 + G ++ + +V PIGV G I P+NFP+++ W A+ GNT +LKP+ Sbjct: 118 PSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPS 177 Query: 207 EQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 E+TPL L L ++AG P GV N+V G V I HP+I I+F GS VG+ V Sbjct: 178 ERTPLLTEKLVELFEKAGLPKGVFNVVYGA-HDVVNGILEHPEIKAISFVGSKPVGEYVY 236 Query: 267 EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQV 326 + S NLKRV G KN IV DA+L+ V F + G+ C A + V VEE + Sbjct: 237 KKGSE-NLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGI 295 Query: 327 YSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG-SA 385 EF+ + E +G+ D GP I + + L IE G +EGA+L C G Sbjct: 296 ADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKRTLSYIEKGLEEGARLVCDGREN 355 Query: 386 MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 + D G F+ PT+F VT M I K+EIF PV +++ K+++E I+ AN +++ A +FT Sbjct: 356 VSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKNLKEAIEIANKSEFANGACLFT 415 Query: 446 KNLDKALKLASALESGTVWIN-CYNALYAQAPFGGFKMS--GNGRELGEYALAEYTEVKT 502 N + +++G + IN A A PF G+K S G G+ ++ YT K Sbjct: 416 SNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFFGTLHANGKDSVDFYTRKKV 475 Query: 503 VTIKLGDK 510 VT + Sbjct: 476 VTARYPAP 483 >5X5U-A nrPDB Length = 505 Score = 501 bits (1290), Expect = e-142, Method: Composition-based stats. Identities = 164/481 (34%), Positives = 245/481 (50%), Gaps = 6/481 (1%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRG 85 N+ T++ I+ EW ++ SGK NP+T + I V D+D+A+ AAQ F+ Sbjct: 27 NVTYTDTQLLIDGEWVDAASGKTIDVVNPATGKPIGRVAHAGIADLDRALAAAQSGFE-- 84 Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 WR++ A R + + A LV +A L T + GKP A +++ + +FA Sbjct: 85 -AWRKVPAHERAATMRKAAALVRERADAIAQLMTQEQGKPLTEAR-VEVLSAADIIEWFA 142 Query: 146 GWADKIQGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLK 204 ++ G+ +P + EP+G A TPWNFP+ +V KL+ AL G + ++K Sbjct: 143 DEGRRVYGRIVPPRNLGAQQTVVKEPVGPVAAFTPWNFPVNQVVRKLSAALATGCSFLVK 202 Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKL 264 E+TP + L +AG P GV+ +V G + + + HP I K+ FTGST VGK Sbjct: 203 APEETPASPAALLRAFVDAGVPAGVIGLVYGDPAEISSYLIPHPVIRKVTFTGSTPVGKQ 262 Query: 265 VKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEE 324 + A ++KR T+ELGG P IV DAD+ LAV+ A F N GQ C + +R V Sbjct: 263 LASLAGL-HMKRATMELGGHAPVIVAEDADVALAVKAAGGAKFRNAGQVCISPTRFLVHN 321 Query: 325 QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS 384 + EF R V++A+ VG+ + T G + ++ + +I++ +K GA +E GG Sbjct: 322 SIRDEFTRALVKHAEGLKVGNGLEEGTTLGALANPRRLTAMASVIDNARKVGASIETGGE 381 Query: 385 AMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 + +G F PTV + V + + E FGPV I F +EE I AN +GL F Sbjct: 382 RIGSEGNFFAPTVIANVPLDADVFNNEPFGPVAAIRGFDKLEEAIAEANRLPFGLAGYAF 441 Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 T++ L LE G +WIN + + PFGG K SG G E G AL Y K+VT Sbjct: 442 TRSFANVHLLTQRLEVGMLWINQPATPWPEMPFGGVKDSGYGSEGGPEALEPYLVTKSVT 501 Query: 505 I 505 + Sbjct: 502 V 502 >3RHD-A nrPDB Length = 486 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 172/483 (35%), Positives = 266/483 (55%), Gaps = 21/483 (4%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 +FI+ +W + NP + E I ++ + + +A++ A+ + + L Sbjct: 2 MFIDGKWIN---REDMDVINPYSLEVIKKIPALSREEAKEAIDTAE---KYKEVMKNLPI 55 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 R +L +A ++ + LA + +D GKP A +++E I T + A + + + Sbjct: 56 TKRYNILMNIAKQIKEKKEELAKILAIDAGKPIKQAR-VEVERSIGTFKLAAFYVKEHRD 114 Query: 154 KTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213 + IP+DD + FTR EP+G+ GAITP+NFPL + K+APA+ GN +V P+ + PL Sbjct: 115 EVIPSDD-RLIFTRREPVGIVGAITPFNFPLNLSAHKIAPAIATGNVIVHHPSSKAPLVC 173 Query: 214 LYLGSLIKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 + L +I+ A P GV N++ G G VG I + ++N I+FTGS++VG+L+ + A Sbjct: 174 IELAKIIENALKKYNVPLGVYNLLTGAGEVVGDEIVVNEKVNMISFTGSSKVGELITKKA 233 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 K++ LELGG NP IV DADL+ AV +G F GQ C + + V+E + + Sbjct: 234 G---FKKIALELGGVNPNIVLKDADLNKAVNALIKGSFIYAGQVCISVGMILVDESIADK 290 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK 389 F+ V AK VG+P D KT+ GP I + + + +++E EG KL GG DK Sbjct: 291 FIEMFVNKAKVLNVGNPLDEKTDVGPLISVEHAEWVEKVVEKAIDEGGKLLLGGKR--DK 348 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 LF PT+ EV + + K E F PV PI++ + EE+I ANST+YGL +A+FT +++ Sbjct: 349 ALFY-PTIL-EVDRDNILCKTETFAPVIPIIR-TNEEEMIDIANSTEYGLHSAIFTNDIN 405 Query: 450 KALKLASALESGTVWINCYNALY-AQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 K+LK A LE G V IN + PFGG K SG GRE +YA+ E + +KT+ I Sbjct: 406 KSLKFAENLEFGGVVINDSSLFRQDNMPFGGVKKSGLGREGVKYAMEEMSNIKTIIISKA 465 Query: 509 DKN 511 + Sbjct: 466 ENL 468 >2JG7-A nrPDB Length = 510 Score = 498 bits (1282), Expect = e-141, Method: Composition-based stats. Identities = 141/484 (29%), Positives = 235/484 (48%), Gaps = 16/484 (3%) Query: 37 NNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSR 96 N W SG+ + P+ E I V + + ++ V+ + A++ W + A R Sbjct: 27 NGSW--GGSGEVITSYCPANNEPIARVTQATLAEYEETVQKTREAWKM---WADIPAPKR 81 Query: 97 GRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI 156 G ++ Q+ D + + L +L +++ GK ++ +++ + Y G + I G + Sbjct: 82 GEIVRQIGDALRKKIKVLGSLVSLEMGKIYVEGVG-EVQEYVDVCDYAVGLSRMIGGPVL 140 Query: 157 PTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALY 215 P++ + P+G+ G IT +NFP+ + W A AL CGN + K A TPLT++ Sbjct: 141 PSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIALTCGNVCLWKGAPTTPLTSVA 200 Query: 216 L----GSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + ++++ P G + + G +G A++ +++ ++FTGST VGK+V + Sbjct: 201 VTKIVAEVLEQNNLP-GAICSMTCGGADIGTAMAKDERVDLLSFTGSTHVGKMVAMMV-Q 258 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFV 331 R LELGG N IV DADL+L V A GQ CT R+ + E V+ V Sbjct: 259 ERFGRKLLELGGNNAIIVFEDADLNLVVPSAVFASVGTAGQRCTTTRRLMLHESVHDAVV 318 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL 391 R + K+ +GDP+D T GP ++ D+ L IE K++G L CGG M+ G Sbjct: 319 ERIAKAYKQVRIGDPWDPSTLYGPLHTKQAVDQYLAAIEQAKQQGGTLVCGGKVMDRPGN 378 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 +++PT+ + + + I E F P+ +LKFK+ EE N GL++++FTK+L + Sbjct: 379 YVEPTIITGLAHDAPIVHTETFVPILYVLKFKTEEEAFAWNNEVQQGLSSSIFTKDLGRV 438 Query: 452 LKLA--SALESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 + + G V +N + FGG K +G GRE G + +Y T TI Sbjct: 439 FRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDSWKQYMRRSTCTINYS 498 Query: 509 DKNP 512 P Sbjct: 499 KDLP 502 >5VBF-A nrPDB Length = 478 Score = 492 bits (1266), Expect = e-139, Method: Composition-based stats. Identities = 160/475 (33%), Positives = 236/475 (49%), Gaps = 6/475 (1%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 +++I+ +H++ + +P T + E+ D+D AV+AA AF WR Sbjct: 6 PLRLYIDGRFHDADGRRTQPVVDPGTTRVLGELPHATAHDIDAAVQAAHRAF---VTWRH 62 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 L R LL + A L T+ TMD GKP A ++ L + A + Sbjct: 63 ESPLVRSDLLRRAAALARERAETIGRHITMDQGKPLREA-IAEVVSAAEQLEWHAEEGRR 121 Query: 151 IQGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 G+ +P +V+ EPIGVC A +PWNFP + K+A AL G T+VLK E++ Sbjct: 122 TYGRVVPARSPDVMQTVLREPIGVCAAFSPWNFPFSQAMHKIAAALASGCTLVLKGPEES 181 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 P + L L +AG PPG +NIV G V + PQ+ KI+FTGS VGK + A Sbjct: 182 PSAIVALAQLFHDAGLPPGCLNIVWGVPGDVSKQLIEAPQVRKISFTGSVPVGKQLAALA 241 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 + S +KR+T+ELGG P +VCADAD++ A F N GQ C + +R FV+ + Sbjct: 242 A-SLMKRMTMELGGHAPVLVCADADVERAAAMLAAYKFRNAGQVCVSPTRFFVQRAAFDR 300 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK 389 FV ++ VG D GP ++ D+I + +GA++ GG + Sbjct: 301 FVCAYLDAVGTIRVGYGLDAGVTMGPLAHARRVDEIDAFVADATAKGAQIATGGMRLPGP 360 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 G + PTV T + R+ +E FGP+ I+ F +++ + AN +GL + FT + Sbjct: 361 GHYFAPTVVLGPTRDTRLMNDEPFGPIVGIVPFDDLDDALAEANRLPFGLASYAFTTSAR 420 Query: 450 KALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 A +++ ALE+G V IN + A+ PFGG K SG G E G A Y K VT Sbjct: 421 NAHRISRALEAGMVNINHFGMGPAEIPFGGVKDSGFGSEGGMEAFDGYLVTKFVT 475 >4JZ6-A nrPDB Length = 500 Score = 491 bits (1264), Expect = e-139, Method: Composition-based stats. Identities = 173/481 (35%), Positives = 264/481 (54%), Gaps = 14/481 (2%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 TK+FINN W +S + F +P + E + E D KA +AA+ AF+ W+ + Sbjct: 20 TKLFINNAWIDSSDQQTFERKHPVSSEVMTESANATVTDAIKAAQAAEEAFK---TWKDV 76 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R RLL ++AD++E + M+ G L A ++ R A A +I Sbjct: 77 GPSERRRLLLKVADVMESKTPKFIEVMAMEVGASALWA-GFNVHASANVFREAASLATQI 135 Query: 152 QGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 QG+TIPTD + T +P+G +I PWN ++ +A L CGNT+V K +E +P Sbjct: 136 QGETIPTDKAETLSMTLRQPVGPILSIVPWNGTAVLAARAIAYPLVCGNTVVFKGSEFSP 195 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPG---FGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 T + ++EAG P GV+N + P + A+ S +I +I FTGST VG ++ + Sbjct: 196 ATHALITQCVQEAGLPAGVLNYLNSSPDRSPEIADALISAKEIRRINFTGSTRVGSIIAQ 255 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 A++ +LKR LELGGK+P IV DAD++ AV+ A G F QGQ C + R+ V+E++ Sbjct: 256 KAAQ-HLKRCLLELGGKSPLIVLDDADINAAVKAAVFGSFLFQGQICMSTERLVVDEKIA 314 Query: 328 SEFVRRSVEYAKKRPVGDP-FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM 386 EFV R VE ++ VGDP GP + ++I L + +GAK+ CGG A Sbjct: 315 DEFVARFVEKTERLSVGDPCLTGDCIIGPMVSPNSGERINGLFKDAIDKGAKVVCGGMA- 373 Query: 387 EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 +G + T+ V +MRI EE FGP+ +++ K E I+ AN + YGL++ VF + Sbjct: 374 --QGAVMPATILDHVKSDMRIYDEETFGPITVVIRCKGEAEAIRIANDSVYGLSSGVFGR 431 Query: 447 NLDKALKLASALESGTVWINCYNA-LYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 ++++AL++ ++E G V IN AQAP+GG K +G GR G + E+TE+K +TI Sbjct: 432 DINRALRVGMSIEYGCVHINGSTVQNEAQAPYGGTKNTGYGRFDGRAVIDEFTELKWLTI 491 Query: 506 K 506 + Sbjct: 492 E 492 >3RH9-A nrPDB Length = 506 Score = 489 bits (1260), Expect = e-139, Method: Composition-based stats. Identities = 167/471 (35%), Positives = 245/471 (52%), Gaps = 7/471 (1%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 +I W +S G F NP+T I +V + DV AVEA Q A + +PW Sbjct: 15 YIGGRWKDSAGGATFDVYNPATGSVIAKVPSMPEEDVVAAVEAGQSALRLTNPW---PIE 71 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 +R + L + D ++ +R + + M+ GKP+ A +++ Y A + Sbjct: 72 TRRKWLEDIRDGLKENREEIGRILCMEHGKPWKEAQG-EVDYAAGFFDYCAKHISALDSH 130 Query: 155 TIPTDDNVVCFTRH-EPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213 TIP +T H P+GV G I PWNFP+ M+ KL+ AL G V+KPA +TPLT Sbjct: 131 TIPEKPKDCTWTVHYRPVGVTGLIVPWNFPIGMIAKKLSAALAAGCPSVIKPASETPLTM 190 Query: 214 LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSN 273 + S++ + P G+VN+V G +G + H + ++FTGSTEVG+ + + Sbjct: 191 IAFFSVMDKLDLPDGMVNLVMGKASVIGKVLCEHKDVPMLSFTGSTEVGRKLIVDTAEQ- 249 Query: 274 LKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRR 333 +K++ LELGG P IV DADL+ A + F GQ C A+R+FV E+V F ++ Sbjct: 250 VKKLALELGGNAPFIVFDDADLEAAADNLIANKFRGGGQTCVCANRIFVHEKVADAFGQK 309 Query: 334 SVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME-DKGLF 392 E K VGD + + GP I+++ FDK+ ++ +GA L G E GLF Sbjct: 310 LAERVNKMTVGDGMNDGIDIGPLINKQGFDKVKRHLQDALDKGASLVAGKQPAELGDGLF 369 Query: 393 IKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKAL 452 PTV V M +EE FGP+ P+ F++ EEVI N T++GL + VFT + ++A Sbjct: 370 FPPTVVQGVDREMCCYQEETFGPLVPMALFRTEEEVIDAGNDTEFGLASYVFTADAERAQ 429 Query: 453 KLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 ++A+ L G V N +APFGG K SG GRE G L E+ E +TV Sbjct: 430 RVAAGLRFGHVGWNTGTGPTPEAPFGGMKASGIGREGGLEGLFEFVEAQTV 480 >4YWE-A nrPDB Length = 487 Score = 488 bits (1258), Expect = e-138, Method: Composition-based stats. Identities = 180/483 (37%), Positives = 257/483 (53%), Gaps = 9/483 (1%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 + K FI EW + +PS + + G PD+++AV AA+ PW Sbjct: 10 EEAKHFIAGEWTLPAQLETIPVVDPSDGQPFATIARGTAPDIERAVAAARD--AFAGPWG 67 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 A RGR+L +L+ V LAA+E DTGKP A R ++AG AD Sbjct: 68 AASAAERGRVLMRLSARVTDSIEELAAIEARDTGKPLKQARAD-AAALARYFEFYAGAAD 126 Query: 150 KIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 K+ G+T+P T EP GV G I PWN+P+ + + AL GN V+KPAE Sbjct: 127 KLHGETLPYQAGYTVLTVREPHGVTGHIVPWNYPMQIFGRSVGAALAAGNACVVKPAEDA 186 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 L+ L + L EAG P G +NIV G+G GAA++ HP I+ I+FTGS GKLV + A Sbjct: 187 CLSVLRVAELAAEAGLPAGALNIVTGYGHEAGAALARHPGIDHISFTGSPATGKLVTQMA 246 Query: 270 SRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE 329 + +++ VTLELGGK+P IV ADADLD A+ + N GQ C+A SRV +E VY Sbjct: 247 AENHV-PVTLELGGKSPQIVFADADLDAALPVLVSAIVQNGGQTCSAGSRVLIERAVYEP 305 Query: 330 FVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK 389 V R VG P + GP I+ KQ ++ + + + +G + G + D Sbjct: 306 LVERLATAFNGLRVG-PSRADLDCGPLINAKQQQRVWDFLSDAQHDGIPMAAHGQVVADA 364 Query: 390 ---GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 G + P + +V + R+A+EE+FGPV ++F +E + AN T YGL A ++T+ Sbjct: 365 PESGFYQAPALLRDVPPSHRLAQEEVFGPVLAAMRFVDEDEAVALANGTPYGLVAGIWTR 424 Query: 447 NLDKALKLASALESGTVWINCYNALYA-QAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 + + ++LA L +G V+IN Y A + PFGG SG+GRE G AL +T +KT+ I Sbjct: 425 DGARQMRLARRLRAGQVFINNYGAGGGVELPFGGVGHSGHGREKGFEALYGFTALKTIAI 484 Query: 506 KLG 508 + G Sbjct: 485 RHG 487 >4X0T-A nrPDB Length = 513 Score = 488 bits (1257), Expect = e-138, Method: Composition-based stats. Identities = 142/483 (29%), Positives = 227/483 (46%), Gaps = 14/483 (2%) Query: 37 NNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSR 96 N W G+ T P+ E I V + D ++ V+ A+ A++ W + A R Sbjct: 30 NGSW--GGRGEVITTYCPANNEPIARVRQASVADYEETVKKAREAWKI---WADIPAPKR 84 Query: 97 GRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI 156 G ++ Q+ D + L +L +++ GK + +++ + Y G + I G + Sbjct: 85 GEIVRQIGDALREKIQVLGSLVSLEMGKILVEGVG-EVQEYVDICDYAVGLSRMIGGPIL 143 Query: 157 PTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALY 215 P++ + P+G+ G IT +NFP+ + W A A+ CGN + K A T L ++ Sbjct: 144 PSERSGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNVCLWKGAPTTSLISVA 203 Query: 216 LGSLIK---EAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 + +I E PG + + G +G A++ ++N ++FTGST+VGK V + Sbjct: 204 VTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVNLLSFTGSTQVGKQVGLMV-QE 262 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 R LELGG N I DADL L V A GQ CT A R+F+ E ++ E V Sbjct: 263 RFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFIHESIHDEVVN 322 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLF 392 R + + VG+P+D GP ++ L +E KKEG + GG M+ G + Sbjct: 323 RLKKAYAQIRVGNPWDPNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNY 382 Query: 393 IKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKAL 452 ++PT+ + + + IA E F P+ + KFK+ EEV N GL++++FTK+L + Sbjct: 383 VEPTIVTGLGHDASIAHTETFAPILYVFKFKNEEEVFAWNNEVKQGLSSSIFTKDLGRIF 442 Query: 453 KLA--SALESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGD 509 + + G V +N + FGG K +G GRE G A +Y T TI Sbjct: 443 RWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSK 502 Query: 510 KNP 512 P Sbjct: 503 DLP 505 >2W8P-A nrPDB Length = 487 Score = 486 bits (1251), Expect = e-137, Method: Composition-based stats. Identities = 167/479 (34%), Positives = 251/479 (52%), Gaps = 12/479 (2%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 T F+ W + F +P++ + V + + AV AA AF R WR Sbjct: 12 RTDSFVGGRWLPAA--ATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCR---WRE 66 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 + A R LL + +L+ +++ LA + T ++GKP A ++ L +F+ A + Sbjct: 67 VSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHG-EILYSAFFLEWFSEEARR 125 Query: 151 IQGKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 + G I T + +PIGV ITPWNFP M+ K+ AL G T+V+KPAE T Sbjct: 126 VYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDT 185 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPG---FGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 P +AL L L +AG P GV N++P VG AI + P ++KI+FTGST GK++ Sbjct: 186 PFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILL 245 Query: 267 EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQV 326 A+ S +KRV++ELGG P IV A++D AV A F N GQ +++ V+ + Sbjct: 246 HHAANS-VKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTAVCSNQFLVQRGI 304 Query: 327 YSEFVRRSVEYAKK-RPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA 385 + FV+ E KK VG+ F+ T QGP I++K +K+ + + +GA + GG Sbjct: 305 HDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKR 364 Query: 386 MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 + F +PT+ VT +M EE FGP+ P++KF + EE I AN+ D GL ++ Sbjct: 365 HQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYS 424 Query: 446 KNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 ++ + ++A LE G V +N + PFGG K SG GRE +Y + EY E+K V Sbjct: 425 QDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVC 483 >4DNG-A nrPDB Length = 485 Score = 480 bits (1236), Expect = e-136, Method: Composition-based stats. Identities = 160/482 (33%), Positives = 252/482 (52%), Gaps = 12/482 (2%) Query: 29 VKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPW 88 K FIN +W +SG+ NP + I ++ A + AQ A + W Sbjct: 4 ETLNKSFINGKWTGGESGRTEDILNPYDQSVITTASLATGKQLEDAFDIAQKAQKE---W 60 Query: 89 RRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWA 148 + R +L + + +R + + +TG + + I+LE I L + Sbjct: 61 AKSTTEDRKAVLQKARGYLHENRDDIIMMIARETGGTIIKS-TIELEQTIAILDEAMTYT 119 Query: 149 DKIQG-KTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 206 ++ G K +P+D + P+GV +I+P+NFP+ + + +APA+ GN++V KP Sbjct: 120 GELGGVKEVPSDIEGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGNSVVHKPD 179 Query: 207 EQTPLTA-LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLV 265 QT ++ + + AG P GV+N++ +G + ++P I+FTGST VG+ + Sbjct: 180 IQTAISGGTIIAKAFEHAGLPAGVLNVMLTDVKEIGDGMLTNPIPRLISFTGSTAVGRHI 239 Query: 266 KEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQ 325 E A R+ KR+ LELGG NP V +DAD+D AV+ A G F +QGQ C +R+ V + Sbjct: 240 GEIAGRA-FKRMALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHQD 298 Query: 326 VYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA 385 VY EFV + K+ P GD D KT GP I+++Q +K LE+IE K +G +L G Sbjct: 299 VYDEFVEKFTARVKQLPYGDQTDPKTVVGPLINERQIEKALEIIEQAKTDGIELAVEGKR 358 Query: 386 MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 + G + P VF +N +IA+ E+F P+ I+K S +E I AN T+YGL++AVFT Sbjct: 359 V---GNVLTPYVFVGADNNSKIAQTELFAPIATIIKAGSDQEAIDMANDTEYGLSSAVFT 415 Query: 446 KNLDKALKLASALESGTVWINCYNALY-AQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 +L+K K A ++SG +N + FGG K SG GR + + E+T K ++ Sbjct: 416 SDLEKGEKFALQIDSGMTHVNDQSVNDSPNIAFGGNKASGVGRFGNPWVVEEFTVTKWIS 475 Query: 505 IK 506 I+ Sbjct: 476 IQ 477 >4PXN-A nrPDB Length = 525 Score = 476 bits (1226), Expect = e-135, Method: Composition-based stats. Identities = 150/483 (31%), Positives = 236/483 (48%), Gaps = 17/483 (3%) Query: 38 NEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRG 97 W SG + +P+ + I EV E D ++ + A F W + A RG Sbjct: 44 GAW--GGSGPTVTSTSPTNNQVIAEVVEASVHDYEEGMRAC---FDAAKTWMAIPAPKRG 98 Query: 98 RLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIP 157 ++ Q+ D + L L +++ GK +++ I Y G + ++ G IP Sbjct: 99 EIVRQIGDALRAKLHHLGRLVSLEMGKILPEGIG-EVQEIIDMCDYAVGLSRQLNGSIIP 157 Query: 158 TDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYL 216 ++ N + P+GV G IT +NFP +L W AL CGN +V K A TPL + + Sbjct: 158 SERPNHMMMEVWNPLGVVGVITAFNFPCAVLGWNACIALVCGNCVVWKGAPTTPLITIAM 217 Query: 217 GSL----IKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 + +++ P + G G +G AI+ +I ++FTGST G +V++ S + Sbjct: 218 TKIVASVLEKNNLPGAIFTSFCG-GTEIGQAIALDIRIPLVSFTGSTRAGLMVQQQVS-A 275 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVR 332 + LEL G N IV DAD+ LAV GQ CT R+ + E +Y F+ Sbjct: 276 RFGKCLLELSGNNAIIVMDDADIQLAVRSVLFAAVGTAGQRCTTCRRLILHENIYQTFLD 335 Query: 333 RSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLF 392 + VE K+ +GDP + T GP + L+ I++ K +G K+ GGSA+E +G F Sbjct: 336 QLVEVYKQVRIGDPLEKGTLLGPLHTPASKENFLKGIQTIKSQGGKILFGGSAIESEGNF 395 Query: 393 IKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKAL 452 ++PT+ E+T + + KEE+FGPV ++KF++++E I+ NS GL++++FTK D Sbjct: 396 VQPTIV-EITPSAPVVKEELFGPVLYVMKFQTLKEAIEINNSVPQGLSSSIFTKRPDIIF 454 Query: 453 KLA--SALESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGD 509 K + G V +N N FGG K +G GRE G + +Y T TI G Sbjct: 455 KWLGPHGSDCGIVNVNIPTNGAEIGGAFGGEKATGGGREAGSDSWKQYMRRATCTINYGS 514 Query: 510 KNP 512 + P Sbjct: 515 ELP 517 >5UR2-A nrPDB Length = 984 Score = 476 bits (1225), Expect = e-134, Method: Composition-based stats. Identities = 176/515 (34%), Positives = 275/515 (53%), Gaps = 21/515 (4%) Query: 5 NGAVENGQPDRKPPALPRPIRNLEVKF---TKIFINNEWHESKSGKKFATCNPS-TREQI 60 N + + + + + + I INN+ E +SGK F NPS + + + Sbjct: 467 NEPLLDFAVKADREKMLKALAEAKASLPVNVNIVINNK--ELQSGKIFDRVNPSQSDQIV 524 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 120 +++ ++A++AAQ A++ W+ + R L+ +LAD++ RDR L A + + Sbjct: 525 GKIQMATTEQAEQAMQAAQTAYK---TWKNVPCEQRAALVDKLADIMTRDRFKLIATQVL 581 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK-TIPTDDNVVCFTRHEPIGVCGAITP 179 + GKP+ A D+ I RY+A ++Q + + ++ GV I P Sbjct: 582 EVGKPWAEADG-DIGEAIDFCRYYARHMRELQKPLRVGGLPGELSHYIYKSRGVTAVIAP 640 Query: 180 WNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPT 239 WNFPL +L + A GNT+V+KPAEQ+ + A L +I+EAGFP GV+N +PG+G Sbjct: 641 WNFPLAILAGMVTAAAVAGNTVVMKPAEQSTVVAWGLMKMIQEAGFPQGVINFLPGYGEE 700 Query: 240 VGAAISSHPQINKIAFTGSTEVGKLVKEAAS-----RSNLKRVTLELGGKNPCIVCADAD 294 VG I +H IAFTGS VG + A+ + ++KR +E+GGKN I+ DAD Sbjct: 701 VGEYIVNHKYTTTIAFTGSKAVGLHIMNRAAVVQPGQQHVKRCIIEMGGKNAVIIDNDAD 760 Query: 295 LDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQG 354 LD AV+ F GQ C+AASRV V ++VY FV R VE AK + + K G Sbjct: 761 LDEAVDGVIYSAFGFSGQKCSAASRVIVLDEVYDRFVDRLVETAKSIEIHPAENPKAYMG 820 Query: 355 PQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFG 414 P +D++ +D+IL I ++ KL GS + G F PT+F +V + ++A+ EIFG Sbjct: 821 PVVDKEAYDRILGTIAEA-EKNHKLLFKGS-VPGGGFFAPPTIFGDVPGDAKLAQAEIFG 878 Query: 415 PVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN--CYNALY 472 PV +++ K++++ + ANST+Y LT VF+++ ++ LE G +++N A+ Sbjct: 879 PVVAVIRAKNLDQALDIANSTEYALTGGVFSRSPANINRVKEELEVGNLYVNRGITGAMV 938 Query: 473 AQAPFGGFKMSGNGRE-LGEYALAEYTEVKTVTIK 506 + PFGGFKMSG G + G L +Y E VT Sbjct: 939 DRHPFGGFKMSGIGSKTGGPDYLKQYMEPACVTEN 973 >5TJR-A nrPDB Length = 531 Score = 475 bits (1222), Expect = e-134, Method: Composition-based stats. Identities = 147/487 (30%), Positives = 239/487 (49%), Gaps = 16/487 (3%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K I E + +G+ NPST E + +V D+ + +A++AA+ AF WR Sbjct: 38 KHLIGGELI-ADTGRTADVFNPSTGEAVRKVPLADRETMQQAIDAAKAAF---PAWRNTP 93 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R ++L + L+E + + L + + GK A +L+ I + Y + ++ Sbjct: 94 PAKRAQVLFRFKQLLEANEERIVKLISEEHGKTIEDAAG-ELKRGIENVEYATAAPEILK 152 Query: 153 GK-TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G+ + N+ ++ +PIGV ITP+NFP ++ +W A+ CGNT +LKP+E+ P Sbjct: 153 GEYSRNVGPNIDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPS 212 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 + L + L EAG P GV+N+V G V A+ P++ ++F GST + + + ++ Sbjct: 213 STLLIAELFHEAGLPKGVLNVVHGDKGAV-DALIEAPEVKALSFVGSTPIAEYIYSEGTK 271 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS-RVFVEEQVYSEF 330 KRV G KN ++ DADLD AV + + G+ C A S V V +Q+ Sbjct: 272 RG-KRVQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQIADAL 330 Query: 331 VRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGS----AM 386 V++ V K +G + GP + DK+ I++G +GA+L G A Sbjct: 331 VQKLVPQIKGLKIGAGTSCGLDMGPLVTGAARDKVTGYIDTGVAQGAELVVDGRGYKVAG 390 Query: 387 EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 + G F+ T+F VT M I KEEIFGPV I++ S+EE ++ N +YG +FT+ Sbjct: 391 HENGFFLGGTLFDRVTPEMTIYKEEIFGPVLCIVRVNSLEEAMQLINDHEYGNGTCIFTR 450 Query: 447 NLDKALKLASALESGTVWINCY-NALYAQAPFGGFKMS--GNGRELGEYALAEYTEVKTV 503 + + A +E G V +N A FGG+K S G+ G + YT+ K + Sbjct: 451 DGEAARLFCDEIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTKRKAI 510 Query: 504 TIKLGDK 510 T + + Sbjct: 511 TQRWPQR 517 >2J5N-A nrPDB Length = 516 Score = 473 bits (1218), Expect = e-134, Method: Composition-based stats. Identities = 174/516 (33%), Positives = 262/516 (50%), Gaps = 28/516 (5%) Query: 5 NGAVENGQPDRKPPALPRPIRNLEVKFTK---IFINNEWHESKSGKKFATCNP-STREQI 60 N +E Q + A+ +R + +F + ++I EW + + ++ + NP + E + Sbjct: 8 NEPIETFQTEEARRAMREALRRVREEFGRHYPLYIGGEWVD--TKERMVSLNPSAPSEVV 65 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETM 120 + K + + A+EAA AF+ W R RLL + A L+ R + L A Sbjct: 66 GTTAKAGKAEAEAALEAAWKAFKTWKDW---PQEDRSRLLLKAAALMRRRKRELEATLVY 122 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI-----PTDDNVVCFTRHEPIGVCG 175 + GK ++ A D+ I + Y+A A + + + P +DN + P+G Sbjct: 123 EVGKNWVEAS-ADVAEAIDFIEYYARAALRYRYPAVEVVPYPGEDNESFYV---PLGAGV 178 Query: 176 AITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPG 235 I PWNFP+ + + + GNT++ KPAE + + + EAGFPPGVVN +PG Sbjct: 179 VIAPWNFPVAIFTGMIVGPVAVGNTVIAKPAEDAVVVGAKVFEIFHEAGFPPGVVNFLPG 238 Query: 236 FGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA-----SRSNLKRVTLELGGKNPCIVC 290 G VGA + HP+I I FTGS EVG + EAA ++ KR +E GGK+ IV Sbjct: 239 VGEEVGAYLVEHPRIRFINFTGSLEVGLKIYEAAGRLAPGQTWFKRAYVETGGKDAIIVD 298 Query: 291 ADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVK 350 AD DLA E + QGQ C+AASR+ + + Y + R ++ A++ VG P + Sbjct: 299 ETADFDLAAEGVVVSAYGFQGQKCSAASRLILTQGAYEPVLERVLKRAERLSVG-PAEEN 357 Query: 351 TEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKE 410 + GP + +Q K+L IE GK EG +L GG +E +G FI PTVF+EV RIA+E Sbjct: 358 PDLGPVVSAEQERKVLSYIEIGKNEG-QLVLGGKRLEGEGYFIAPTVFTEVPPKARIAQE 416 Query: 411 EIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN--CY 468 EIFGPV +++ K E ++ AN T YGLT V+++ + G ++ N Sbjct: 417 EIFGPVLSVIRVKDFAEALEVANDTPYGLTGGVYSRKREHLEWARREFHVGNLYFNRKIT 476 Query: 469 NALYAQAPFGGFKMSGNGRELG-EYALAEYTEVKTV 503 AL PFGGFK+SG + G L + E+K V Sbjct: 477 GALVGVQPFGGFKLSGTNAKTGALDYLRLFLEMKAV 512 >3PRL-A nrPDB Length = 505 Score = 473 bits (1217), Expect = e-133, Method: Composition-based stats. Identities = 164/493 (33%), Positives = 248/493 (50%), Gaps = 18/493 (3%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRG 85 E I N EW ES++G++ + P++ + + + +V+ A++ A+ A + Sbjct: 6 QTEQFNANILRNGEWVESRTGERISISAPASGVALGSIPALSQEEVNDAIQGAKDAQKI- 64 Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 W+ R LL+ ADL+E + + L + KP A ++ +R+ A Sbjct: 65 --WKIRPIHERVDLLYAWADLLEERKEIIGELIMHEVAKPKKSAIG-EVSRTADIIRHTA 121 Query: 146 GWADKIQGKTIPTDD------NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGN 199 A ++ G+T+ D + EP+GV AI+P+N+P+ + K+APAL GN Sbjct: 122 DEALRLNGETLKGDQFKGGSSKKIALVEREPLGVVLAISPFNYPVNLAAAKIAPALVTGN 181 Query: 200 TMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 T+V KPA Q L+ + + + +AG P G++ +V G G +G + HP I+ I FTG T Sbjct: 182 TVVFKPATQGSLSGIKMVEALADAGAPEGIIQVVTGRGSVIGDHLVEHPGIDMITFTGGT 241 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319 G+ + E A + V LELGGK+P IV DADL L G F GQ CTA R Sbjct: 242 TTGERISEKAK---MIPVVLELGGKDPAIVLDDADLKLTASQIVSGAFSYSGQRCTAIKR 298 Query: 320 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKL 379 VFV++ V + V E ++ VG P D + P ID+K I LI+ + GA L Sbjct: 299 VFVQDSVADQLVANIKELVEQLTVGSPED-DADITPVIDEKSAAFIQGLIDDALENGATL 357 Query: 380 ECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGL 439 G +G + PT+ +VT MR+A EE FGPV PI++ K E I +N +DYGL Sbjct: 358 LSGNKR---QGNLLSPTLLDDVTPAMRVAWEEPFGPVLPIIRVKDANEAISLSNQSDYGL 414 Query: 440 TAAVFTKNLDKALKLASALESGTVWINCYNALYAQA-PFGGFKMSGNGRELGEYALAEYT 498 A++FTK+ D+A+ + LE GTV IN PF G K SG G + + +L T Sbjct: 415 QASIFTKDTDRAINIGKHLEVGTVHINAKTERGPDHFPFLGVKKSGLGVQGIKPSLLSMT 474 Query: 499 EVKTVTIKLGDKN 511 + + L + Sbjct: 475 RERVTVLNLAENL 487 >2QE0-A nrPDB Length = 475 Score = 471 bits (1213), Expect = e-133, Method: Composition-based stats. Identities = 157/482 (32%), Positives = 243/482 (50%), Gaps = 20/482 (4%) Query: 33 KIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 K ++N EW S++ P++ ++ V +VD +A+ A WR L Sbjct: 6 KNYVNGEWKLSENE--IKIYEPASGAELGSVPAMSTEEVDYVYASAKKAQ---PAWRALS 60 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 + R LH++AD++ RD+ + A+ + + K + A ++ + Y A +++ Sbjct: 61 YIERAAYLHKVADILMRDKEKIGAILSKEVAKGYKSAVS-EVVRTAEIINYAAEEGLRME 119 Query: 153 GKTIP------TDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPA 206 G+ + + R EP+G+ AI+P+N+P+ + K+APAL GN + KP Sbjct: 120 GEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPP 179 Query: 207 EQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 Q ++ L L EAG P GV N + G G +G I H +N I FTGST +G+ + Sbjct: 180 TQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGERIG 239 Query: 267 EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQV 326 + A ++ + L LGGK+ IV DADL+L + G F GQ CTA RV V E V Sbjct: 240 KMAG---MRPIMLALGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVLVMESV 296 Query: 327 YSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM 386 E V + E +G+P D + P ID K D + LI +GA + Sbjct: 297 ADELVEKIREKVLALTIGNPED-DADITPLIDTKSADYVEGLINDANDKGATALT---EI 352 Query: 387 EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTK 446 + +G I P +F +VT +MR+A EE FGPV PI++ S+EE I+ +N ++YGL A++FT Sbjct: 353 KREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYGLQASIFTN 412 Query: 447 NLDKALKLASALESGTVWINCYNALYAQ-APFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 + +A +A LE GTV IN PF G K SG G + +Y++ T VK+V Sbjct: 413 DFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAMTTVKSVVF 472 Query: 506 KL 507 + Sbjct: 473 DI 474 >3R64-A nrPDB Length = 508 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 174/487 (35%), Positives = 258/487 (52%), Gaps = 11/487 (2%) Query: 29 VKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPW 88 + TK I +W E S + NP I E ++ DVD A EAA+ A + W Sbjct: 10 IDATKHLIGGQWVEGNSDRISTNINPYDDSVIAESKQASIADVDAAYEAAKKAQ---AEW 66 Query: 89 RRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWA 148 A R ++++ A+L+E R + ++G A +++ + A + Sbjct: 67 AATPAAERSAIIYRAAELLEEHREEIVEWLIKESGSTRSKA-NLEITLAGNITKESASFP 125 Query: 149 DKIQGKTIPTDD-NVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 ++ G+ P++ GV G I+PWNFPL + + +APAL GN +V+KPA Sbjct: 126 GRVHGRISPSNTPGKENRVYRVAKGVVGVISPWNFPLNLSIRSVAPALAVGNAVVIKPAS 185 Query: 208 QTPLTALYL-GSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVK 266 TP+T + + +EAG P GV++ V G G +G +H I+FTGST VG+ V Sbjct: 186 DTPVTGGVIPARIFEEAGVPAGVISTVAGAGSEIGDHFVTHAVPKLISFTGSTPVGRRVG 245 Query: 267 EAASRSN-LKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQ 325 E A +K V LELGG P +V ADAD+D A + A G F +QGQ C + +RV V+ Sbjct: 246 ELAINGGPMKTVALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVIVDAA 305 Query: 326 VYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSA 385 V+ EF+ + VE K P GDP T GP I+ Q + E IE KKEGA ++ G Sbjct: 306 VHDEFLEKFVEAVKNIPTGDPSAEGTLVGPVINDSQLSGLKEKIELAKKEGATVQVEGPI 365 Query: 386 MEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFT 445 +G + P VFS+VT +M IA+EEIFGP+ +LK + AN++D+GL+AAV++ Sbjct: 366 ---EGRLVHPHVFSDVTSDMEIAREEIFGPLISVLKADDEAHAAELANASDFGLSAAVWS 422 Query: 446 KNLDKALKLASALESGTVWINCYNALY-AQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 K++D+A + A ++SG V IN FGG K SG GR G++A+ E+T + + Sbjct: 423 KDIDRAAQFALQIDSGMVHINDLTVNDEPHVMFGGSKNSGLGRFNGDWAIEEFTTDRWIG 482 Query: 505 IKLGDKN 511 IK +N Sbjct: 483 IKRSAEN 489 >4ZZ7-A nrPDB Length = 501 Score = 467 bits (1202), Expect = e-132, Method: Composition-based stats. Identities = 141/482 (29%), Positives = 240/482 (49%), Gaps = 16/482 (3%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 IN + + + NP+T E +++ V++A+ AAQ AF WR Sbjct: 9 HLINGQLVTENT-RSQNVFNPATGEIGKQLDLASTKTVEQAISAAQHAF---PTWRNTPP 64 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 L R R++ + +L+E+ + L + GK H +L+ I + Y G + ++G Sbjct: 65 LKRARVMFRFKELLEQHADEICRLIGEEHGK-IAHDAMGELQRGIENVEYACGAPELLKG 123 Query: 154 K-TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 + + + ++ +P+GV ITP+NFP+++ +W A+ CGN VLKP+E+ P + Sbjct: 124 EHSRNVGPGIDSWSEFQPMGVVAGITPFNFPVMVPLWMFPMAIVCGNCFVLKPSERDPSS 183 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 LY+ L++EAG P GV+N+V G V A+ ++ ++F GST + + + AS + Sbjct: 184 TLYIAQLLQEAGLPDGVMNVVNGDKEAV-DALLHDDRVKAVSFVGSTPIAEYIYRTAS-A 241 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS-RVFVEEQVYSEFV 331 N KR G KN IV DAD+D AV F + G+ C A S V V + V Sbjct: 242 NGKRCQALGGAKNHAIVMPDADMDNAVNQLLGAAFGSSGERCMALSVAVAVGDAAGDALV 301 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME---- 387 + + +K VG D + GP I ++ +K++ I S +++GA + G + Sbjct: 302 SKMTQAMQKLKVGPSTDSGNDFGPVITRQHQEKVIGYINSAEQQGATIVVDGRQPKVPNH 361 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 + G F+ T+ VT M +EEIFGPV +++ ++++ + ++ +YG +FT++ Sbjct: 362 ENGFFVGGTLIDHVTPEMTSYQEEIFGPVLQVVRVATMQDAMDLIDAHEYGNGTCIFTRD 421 Query: 448 LDKALKLASALESGTVWINCY-NALYAQAPFGGFKMS--GNGRELGEYALAEYTEVKTVT 504 + A + ++ G V IN A FGG+K S G+ G A+ YT+ KTVT Sbjct: 422 GEAARYFSDNIQVGMVGINIPLPVPVAYHSFGGWKRSLFGDLHAYGPDAVRFYTKRKTVT 481 Query: 505 IK 506 + Sbjct: 482 QR 483 >6MVR-A nrPDB Length = 767 Score = 466 bits (1199), Expect = e-131, Method: Composition-based stats. Identities = 191/471 (40%), Positives = 269/471 (57%), Gaps = 24/471 (5%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 FI W G FAT NP+T + + +V + + DVD AV+AA+ A W + D Sbjct: 35 HFIGGAWTAP--GDLFATVNPATGQTLAQVSQATQADVDAAVKAARKAQ---PAWAK-DG 88 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 +R R+L+ LA L+++ A LET+D GKP A ID+ R + AG+A ++ G Sbjct: 89 AARARVLYALARLLQKHARLFAVLETLDNGKPIREARDIDVPLAQRHFYHHAGYA-QLMG 147 Query: 154 KTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTA 213 +P P+GVCG + PWNFPLLML WK+APAL GNT+VLKPAE TPLTA Sbjct: 148 TEMPD---------RAPLGVCGQVIPWNFPLLMLAWKIAPALAMGNTVVLKPAEWTPLTA 198 Query: 214 LYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSN 273 L + +AG P GVVNIV G G VG I + Q++K+AFTGST VG+ ++EA + + Sbjct: 199 LLFADICGQAGVPAGVVNIVTGDGA-VGEMIVT-AQVDKVAFTGSTAVGRRIREATAGTG 256 Query: 274 LKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRR 333 K ++LELGGK P +VC DAD+D AVE ++FNQGQ C A SR+ V+E + F + Sbjct: 257 -KALSLELGGKGPYVVCDDADIDSAVEGLVDAIWFNQGQVCCAGSRLLVQEGIADVFHAK 315 Query: 334 SVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFI 393 +GDP D + G + Q ++ +++ + +G + A G + Sbjct: 316 LRARMDSLRIGDPLDKCIDIGAMVHPDQLARVRDMV-AANTDGEVYQTAVPA----GCYY 370 Query: 394 KPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALK 453 PT+ S + + ++EIFGPV F++ E ++ AN+T YGL A+V+++N++ AL Sbjct: 371 PPTLISGLAPASPLMQQEIFGPVLVSTTFRTPAEAVEIANNTAYGLAASVWSENVNLALD 430 Query: 454 LASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVT 504 LA L +G VWIN N + A APFGG + SG GRE G LA YT T Sbjct: 431 LAPKLVAGIVWINGTNMMDAAAPFGGVRESGFGREGGWEGLAGYTRPAIAT 481 Score = 129 bits (325), Expect = 3e-30, Method: Composition-based stats. Identities = 66/247 (26%), Positives = 100/247 (40%), Gaps = 12/247 (4%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 + K++I + G A P + + ++ D+ AVEA A S W Sbjct: 501 RTAKLYIGGKQTRPDGGYSRAVYGPK-GKLLGHASLSNRKDLRNAVEAMNAA----SGWS 555 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R R ++L+ + + + A TGK ++ I L A WAD Sbjct: 556 RTTGHLRAQILYFIGENLSARADEFANRIKDMTGK----DGKAEVAASIDRLFSAAAWAD 611 Query: 150 KIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 K G+ V EP+G G + P PLL LV +APA+ GN + L +E Sbjct: 612 KYDGQVKGVPLRGVALAMKEPVGKIGILCPDAAPLLGLVSLMAPAIAMGNRVTLAASEAF 671 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 PL A ++ + P GVVNI+ G + ++ H ++ + V EAA Sbjct: 672 PLAATDFYQVLDTSDVPAGVVNILTGAHADLAEPMARHLDLDAVW---GLSGHAQVIEAA 728 Query: 270 SRSNLKR 276 S NLKR Sbjct: 729 SAGNLKR 735 >6FK3-A nrPDB Length = 536 Score = 465 bits (1197), Expect = e-131, Method: Composition-based stats. Identities = 188/499 (37%), Positives = 257/499 (51%), Gaps = 29/499 (5%) Query: 34 IFINNEWHESKSGKKFATCNPSTRE-QICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD 92 + E E G NPS RE + E DK V KA A+ AF + W R Sbjct: 22 HLVGGE--EVLEGPLLERRNPSDREDVVARFPEADKDLVRKAALKAREAF---AEWSRTP 76 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 A RG++L L ++ER++ TL L + GK A D++ I T +FA ++ Sbjct: 77 APIRGQVLFNLVKILEREKPTLTRLMVREVGKTPKEAAG-DVQEAIDTALFFASEGRRLY 135 Query: 153 GKTIPTD-DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G+T+P++ + FT P+GV G IT NFP+ + WKL PA+ GNT+V KP+E P Sbjct: 136 GQTVPSEMRDKELFTFRRPLGVVGIITAGNFPIAVPSWKLIPAVLTGNTVVWKPSEDAPT 195 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGP-TVGAAISSHPQ---INKIAFTGSTEVGKLVKE 267 + L +EAG PPGV+N+V G G + G + K AFTGST+VG+ + E Sbjct: 196 LSFVFAKLFEEAGLPPGVLNVVFGGGKGSTGQWMVELMDEGLFQKFAFTGSTQVGRWIGE 255 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 A R NL R TLELGGKNP +V DADLDLAVE A F GQ CT+A + V+ +Y Sbjct: 256 VAGR-NLIRPTLELGGKNPLVVMRDADLDLAVEGAWWSAFATGGQRCTSAGNILVDAPIY 314 Query: 328 SEFVRRSVEYAKKRPVGDP-FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAM 386 EF RR +E + VG+P + GP I+++ F + E G+ EGA+L G + Sbjct: 315 EEFKRRFLERVEATLVGNPLLHPEVTYGPFINERFFARWQEHYRVGEAEGARLLFGRGRI 374 Query: 387 ------------EDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANS 434 + GL+ PTV+ EV R+ EE+FGP ++K IEE I ANS Sbjct: 375 TRENPYPRFLGDPEAGLYGWPTVW-EVRPGTRLFTEEVFGPTINLVKVDGIEEAIAVANS 433 Query: 435 TDYGLTAAVFTKNLDKALKLASALESGTVWINCYN-ALYAQAPFGGFKMSGN-GRELGEY 492 T YGL++A++T + A + +G IN A PFGG K SGN GRE G + Sbjct: 434 TPYGLSSAIYTNHRHWAYLFKVGIRAGMTSINNATVGAEAHLPFGGVKASGNGGRESGIW 493 Query: 493 ALAEYTEVKTVTIKLGDKN 511 L EYT V + + Sbjct: 494 VLEEYTYWHAVNEEYSGRL 512 >3EFV-A nrPDB Length = 462 Score = 460 bits (1185), Expect = e-130, Method: Composition-based stats. Identities = 141/456 (30%), Positives = 221/456 (48%), Gaps = 6/456 (1%) Query: 51 TCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERD 110 + NP+T + + + + +++ A+ A F++ W+ R + L + + Sbjct: 11 SVNPATGQTLAAMPWANAQEIEHALSLAASGFKK---WKMTSVAQRAQTLRDIGQALRAH 67 Query: 111 RATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEP 170 +A T + GKP A ++ ++A + +N + P Sbjct: 68 AEEMAQCITREMGKPIKQAR-AEVTKSAALCDWYAEHGPAMLNPEPTLVENQQAVIEYRP 126 Query: 171 IGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVV 230 +GV AI PWNFPL ++ P L GN+ +LK A A + ++ EAG P GV Sbjct: 127 LGVILAIMPWNFPLWQVLRGAVPILLAGNSYLLKHAPNVTGCAQMIARILAEAGTPAGVY 186 Query: 231 NIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVC 290 V V + + P+I + TGS A + + LK+ LELGG +P IV Sbjct: 187 GWVNANNEGVSQ-MINDPRIAAVTVTGSVRA-GAAIGAQAGAALKKCVLELGGSDPFIVL 244 Query: 291 ADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVK 350 DADL+LAV+ A G + N GQ C AA R VEE + F R V A +GDP + Sbjct: 245 NDADLELAVKAAVAGRYQNTGQVCAAAKRFIVEEGIAQAFTDRFVAAAAALKMGDPLVEE 304 Query: 351 TEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKE 410 + GP D++ + +++ EGA+L GG + +G + TV ++VT +M ++ Sbjct: 305 NDLGPMARFDLRDELHQQVQASVAEGARLLLGGEKIAGEGNYYAATVLADVTPDMTAFRQ 364 Query: 411 EIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNA 470 E+FGPV I K + AN +++GL+A +FT + A ++A+ LE G V+IN Y+A Sbjct: 365 ELFGPVAAITVAKDAAHALALANDSEFGLSATIFTADDTLAAEMAARLECGGVFINGYSA 424 Query: 471 LYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 A+ FGG K SG GREL + L E+ V+TV Sbjct: 425 SDARVAFGGVKKSGFGRELSHFGLHEFCNVQTVWKN 460 >4OGD-A nrPDB Length = 465 Score = 458 bits (1179), Expect = e-129, Method: Composition-based stats. Identities = 144/460 (31%), Positives = 222/460 (48%), Gaps = 9/460 (1%) Query: 49 FATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLD-ALSRGRLLHQLADLV 107 + T P T E + + + +E A + +++ WR+ D R LHQ+A+++ Sbjct: 3 YQTIYPYTNEVLHTFDNMTDQGLADVLERAHLLYKK---WRKEDHLEERKAQLHQVANIL 59 Query: 108 ERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR 167 RDR A + T D GK F A +++ C Y+A AD+ T D+ + Sbjct: 60 RRDRDKYAEIMTKDMGKLFTEAQG-EVDLCADIADYYADKADEFLMSTPLETDSGQAYYL 118 Query: 168 HEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPP 227 + GV A+ PWNFP ++ AP GN MVLK A P +A L+ EAG Sbjct: 119 KQSTGVILAVEPWNFPYYQIMRVFAPNFIVGNPMVLKHASICPRSAQSFEELVLEAGAEA 178 Query: 228 G-VVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNP 286 G + N+ + + + + ++ + TGS G + E A + NLK+ TLELGG + Sbjct: 179 GSITNLFISYDQV--SQVIADKRVVGVCLTGSERGGASIAEEAGK-NLKKTTLELGGDDA 235 Query: 287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 I+ DAD D + + +N GQ CT++ R V ++ Y F + K GDP Sbjct: 236 FIILDDADWDQLEKVLYFSRLYNAGQVCTSSKRFIVLDKDYDRFKELLTKVFKTAKWGDP 295 Query: 347 FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMR 406 D +T P + +L+ I+ GA+L GG A++ G F+ PT+ + +T + Sbjct: 296 MDPETTLAPLSSAQAKADVLDQIKLALDHGAELVYGGEAIDHPGHFVMPTIIAGLTKDNP 355 Query: 407 IAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN 466 I +EIFGPV I K S EE I+ AN ++YGL +F+ N + A +A+ +E+G +IN Sbjct: 356 IYYQEIFGPVGEIYKVSSEEEAIEVANDSNYGLGGTIFSSNQEHAKAVAAKIETGMSFIN 415 Query: 467 CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 + PFGG K SG GREL E + + I Sbjct: 416 SGWTSLPELPFGGIKHSGYGRELSELGFTSFVNEHLIYIP 455 >3ROS-A nrPDB Length = 484 Score = 455 bits (1172), Expect = e-128, Method: Composition-based stats. Identities = 136/465 (29%), Positives = 224/465 (48%), Gaps = 9/465 (1%) Query: 48 KFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLV 107 K+ + NP T E + +D+A+ A +++ WR + SR +LH +A+ + Sbjct: 5 KYQSVNPYTNEAFASYDNPTSKQIDEAINLAHALYKK---WRHEEPASRAEILHDIANAL 61 Query: 108 ERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR 167 + LA + T++ GK + ++E C+ Y+A ++ T D + Sbjct: 62 KEHEDELAKMMTLEMGKLLSESK-EEVELCVSICNYYADHGPEMLKPTKLNSDLGNAYYL 120 Query: 168 HEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPP 227 + GV A PWNFPL ++ AP GN ++LK A P +A +IK AG P Sbjct: 121 KQSTGVIMACEPWNFPLYQVIRVFAPNFIVGNPILLKHAHNVPGSAALTAKIIKRAGAPE 180 Query: 228 G-VVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNP 286 G ++N+ P + A I + P+I +A TGS G V EAA + NLK+ T+ELGG + Sbjct: 181 GSLINLYPSYDQL--ADIIADPRIQGVALTGSERGGSAVAEAAGK-NLKKSTMELGGNDA 237 Query: 287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 IV DAD + + +N GQ CT++ R+ VE+ Y E + GDP Sbjct: 238 FIVLDDADPQVLRNVLNDARTYNDGQVCTSSKRIIVEKSRYDEVLHELKNVFSNLKAGDP 297 Query: 347 FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMR 406 + T P +K +K+ ++ GAK+ ++ KG F +PT+ +++ + Sbjct: 298 LEADTTLPPMNSEKAKEKLEAQVKEAIDAGAKVFYQYPEIDSKGAFFRPTILTDIAKDNP 357 Query: 407 IAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN 466 + +E+FGP+ + + I+ AN + YGL ++V ++D+A K+++ +E+G IN Sbjct: 358 VFDKEVFGPIAEVFVVEDDNAAIQLANDSSYGLGSSVIGSDIDRAKKVSAQIETGMTVIN 417 Query: 467 CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKN 511 + PFGG K SG GREL L + V I + N Sbjct: 418 GRWITSGELPFGGIKKSGYGRELSGLGLMAFVNEHLV-IDVTKNN 461 >3VZ3-A nrPDB Length = 457 Score = 455 bits (1172), Expect = e-128, Method: Composition-based stats. Identities = 140/463 (30%), Positives = 215/463 (46%), Gaps = 6/463 (1%) Query: 44 KSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQL 103 S AT NP+T E + ++D + AQ AFQ +RR R + L Sbjct: 1 GSHMAIATINPTTGEICQRFKALTPAEIDAKLAKAQEAFQ---AYRRTSFSQRRQWLENA 57 Query: 104 ADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVV 163 A ++ERD + A + T + GK A + E RY+A ++ Sbjct: 58 AAILERDTSKFAEIMTTEMGKTHQSA-IAEAEKSALVCRYYAEHGEQFLANEYTETQATE 116 Query: 164 CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA 223 + ++P+G+ A+ PWNFP + APAL GN VLK A P AL + ++++ A Sbjct: 117 SYVCYQPLGILLAVMPWNFPFWQVFRFAAPALMAGNVAVLKHASNVPQCALAVEAILEAA 176 Query: 224 GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGG 283 GFP GV + G + + P++ TGS G + A + +K LELGG Sbjct: 177 GFPEGVFQTLL-IGASQVEQVIKDPRVKAATLTGSEPAGASLASLAGQ-EIKPTLLELGG 234 Query: 284 KNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPV 343 +P +V ADLD AVE N GQ AA R + E + +EF+ + + Sbjct: 235 SDPFVVFPSADLDEAVEVGTVARTMNNGQSAIAAKRFILHEAIAAEFLEKLHLKFASLKI 294 Query: 344 GDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTD 403 GDP +T+ GP + I ++ GAK+ GG ++ G F PT+ +E+ Sbjct: 295 GDPMAPETDIGPLATEGILQDISRQVDQAVAAGAKILLGGRPLDRAGYFYPPTILTEIPP 354 Query: 404 NMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTV 463 +I +EE+F PV + K +++ I AN +GL A+ +T + + + L++G V Sbjct: 355 GAKILQEELFAPVAMVFTVKDLDQAIALANDIPFGLGASAWTNDPAEQQRFIQELDAGAV 414 Query: 464 WINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 +IN + PFGG K SG GRELG + + KTV +K Sbjct: 415 FINGMVKSDPRLPFGGTKRSGYGRELGLAGIRTFVNAKTVWLK 457 >3VZ0-A nrPDB Length = 459 Score = 454 bits (1168), Expect = e-128, Method: Composition-based stats. Identities = 148/459 (32%), Positives = 220/459 (47%), Gaps = 7/459 (1%) Query: 48 KFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLV 107 + T NP+T + + + A+ ++ W+ R ++ + ADL+ Sbjct: 6 VYQTLNPTTETVERSFDLHTPAQMKDITDRAEHVWKT--DWKLRSIAQRKEIVSRAADLL 63 Query: 108 ERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR 167 RDR A+L + GK A +++ L ++A A++ T Sbjct: 64 RRDRQHHASLIATEMGKALPDA-LEEIDVTADILSFYANGAEEFLAPTPLKVKTGQAKII 122 Query: 168 HEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPP 227 ++P+G+ I PWNFP L P L GN ++ K A P AL L +AG P Sbjct: 123 NQPLGIIYCIEPWNFPYYQLARVAGPNLMAGNVVIAKHAPNVPQCALAFEKLFHDAGAPV 182 Query: 228 GVV-NIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNP 286 G NI A + +I +A TGS A + + LK+ T+ELGG + Sbjct: 183 GAYANIF--LDNDQSAELIKDERIRGVALTGSERA-GQAVAAQAGAALKKDTMELGGSDA 239 Query: 287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 IV DADLDLAV+ A G F N GQ CTAA R+ V E+VY F+ + +G+P Sbjct: 240 FIVLDDADLDLAVKWAVWGRFANNGQVCTAAKRMIVHEKVYDAFLDGLKTAITRFRIGNP 299 Query: 347 FDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMR 406 D T GP + + L+ K GA L GG M+ KG F++PT+ ++V+ + Sbjct: 300 LDRDTTHGPMSSLRAMELALDQTAEAVKGGATLVAGGKRMDRKGFFMEPTILTDVSKDNP 359 Query: 407 IAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWIN 466 + +EIFGPV + K S + I AN + YGL AVF++++ +A K+A +E+G V+IN Sbjct: 360 VFYQEIFGPVAVVHKVASEQAAIDLANDSPYGLGGAVFSRDIARAEKVAEQVETGMVFIN 419 Query: 467 CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTI 505 A + PFGG K SG GREL + E+ K V I Sbjct: 420 TATAAAPELPFGGIKNSGFGRELSFLGIEEFINRKLVRI 458 >5N5S-A nrPDB Length = 515 Score = 445 bits (1146), Expect = e-125, Method: Composition-based stats. Identities = 155/489 (31%), Positives = 242/489 (49%), Gaps = 20/489 (4%) Query: 26 NLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRG 85 ++ K IF+ ++ + K N T + +V + D+D A++AA A Sbjct: 34 DVTPKKYNIFLASKPVDG-DRKWLDVTNKYTNDVAAKVPQATHKDIDDAIDAAVAAAPAM 92 Query: 86 SPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFA 145 + + A R +L ++ ++ +A TM++GKP A ++ I T + A Sbjct: 93 AA---MGAYERKAVLEKVVAELKNRFEEIAQTLTMESGKPIKDARG-EVTRTIDTFQVAA 148 Query: 146 GWADKIQGKTIPTD-----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNT 200 + +I G+ IP D + + PIG ++PWNFPL ++ K+APA+ G Sbjct: 149 EESVRIYGEHIPLDISARNKGLQGIVKKFPIGPVSMVSPWNFPLNLVAHKVAPAIAVGCP 208 Query: 201 MVLKPAEQTPLTALYLGSLIKEAG-FPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 VLKPA +TPL+AL LG ++ + P G +I+P + + + FTGS Sbjct: 209 FVLKPASRTPLSALILGEILHKIEELPLGAFSILP-VSREDADMFTVDERFKLLTFTGSG 267 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA-DLDLAVECAHQGVFFNQGQCCTAAS 318 +G +K A + K+V +ELGG PCIV DLD ++ G F+ GQ C Sbjct: 268 PIGWDMKARAGK---KKVVMELGGNAPCIVDDYVPDLDYTIQRLINGGFYQGGQSCIHMQ 324 Query: 319 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 R++V E++Y E V KK +G+PF+ T GP I + I + ++ +G K Sbjct: 325 RLYVHERLYDEVKEGFVAAVKKLKMGNPFEEDTYLGPMISESAAKGIEDWVKEAVAKGGK 384 Query: 379 LECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYG 438 L GG+ KG FI+PTV +V KEEIFGPV + K+ +E +K N+T YG Sbjct: 385 LLTGGNR---KGAFIEPTVIEDVPIEANARKEEIFGPVVLLYKYSDFKEAVKECNNTHYG 441 Query: 439 LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQ-APFGGFKMSGNGRELGEYALAEY 497 L + +FTK+L+KA +E G V +N AL P+GG K SG RE +YA+ + Sbjct: 442 LQSGIFTKDLNKAFYAFEHMEVGGVILNDSPALRVDSQPYGGLKDSGIQREGVKYAMDDM 501 Query: 498 TEVKTVTIK 506 E K + ++ Sbjct: 502 LETKVLVMR 510 >5KF0-A nrPDB Length = 485 Score = 444 bits (1142), Expect = e-125, Method: Composition-based stats. Identities = 141/480 (29%), Positives = 221/480 (46%), Gaps = 21/480 (4%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 ++ NE + + + + + V D +D A+ AA A + P R L A Sbjct: 17 YLANEAVYANTD--LEVTDKFSGKVATRVALADAQAIDAAIGAAVDAVK---PMRELPAY 71 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK 154 R +L LA ++ GKP + ++ I T R + A +I G+ Sbjct: 72 RRQAVLDHCVARFRERFDELAEALCIEAGKPINDSRG-EVTRLIDTFRVASEEAVRIDGE 130 Query: 155 TIPTD-----DNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 + + +TR PIG C I+P+NFPL + K+APAL G VLKPA +T Sbjct: 131 VLNLEISARAQGYTGYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRT 190 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 P+ AL + ++ E P G +++P ++ + ++FTGS VG +KE A Sbjct: 191 PVGALIIAEVLAETNLPKGAFSVLPAHRDGA-DLFTTDERFRLLSFTGSPAVGWALKEKA 249 Query: 270 SRSNLKRVTLELGGKNPCIVCADA--DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 + K+V LELGG IV AD LD V+ G ++ GQ C R+ V +Y Sbjct: 250 GK---KKVVLELGGNAAAIVDADQFEQLDYVVDRLAFGAYYQSGQSCIGVQRILVHASLY 306 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 + V + +GDP D T GP I + + ++ +++ GAK+ GG Sbjct: 307 DTLRDKLVAKTRSLKMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGAKIIAGGKV-- 364 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G + T+ +V + ++E FGPV + KF ++ + R N +D+GL A VFT + Sbjct: 365 -DGAMFEATLLEDVGREQDLYRKEAFGPVAILEKFDRFDDALARVNDSDFGLQAGVFTDS 423 Query: 448 LDKALKLASALESGTVWINCYNALYAQ-APFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 L A + LE G V IN + P+GG K SG GRE YA+ + TE + + ++ Sbjct: 424 LTHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTEPRLMVVR 483 >5JRY-A nrPDB Length = 485 Score = 438 bits (1127), Expect = e-123, Method: Composition-based stats. Identities = 138/466 (29%), Positives = 213/466 (45%), Gaps = 19/466 (4%) Query: 49 FATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVE 108 + + + V D +D A+ AA A P R L A R +L Sbjct: 29 LEVTDKYSGKVATRVALADAKAIDAAIGAAVDA---TKPMRELPAYKRQAVLDHCVARFR 85 Query: 109 RDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTD-----DNVV 163 LA ++ GKP A ++ I T R + A +I G+ + + Sbjct: 86 ERFDELAEALCIEAGKPINDAKG-EVTRLIDTFRVASEEAVRIDGEVLNLEISARAQGYT 144 Query: 164 CFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA 223 +TR PIG C I+P+NFPL + K+APAL G VLKPA +TP+ AL +G ++ E Sbjct: 145 GYTRRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRTPVGALIIGEVLAET 204 Query: 224 GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGG 283 P G +++P ++ + ++FTGS VG +KE A + K+V LELGG Sbjct: 205 DLPKGAFSVLPAHRDGA-DLFTTDDRFRLLSFTGSPAVGWALKEKAGK---KKVVLELGG 260 Query: 284 KNPCIVCADA--DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKR 341 IV AD LD V+ G F+ GQ C R+ +Y + + + Sbjct: 261 NAAAIVDADQLDRLDYVVDRLAFGAFYQSGQSCIGVQRILAHADIYDALRDKLIAKTRSL 320 Query: 342 PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEV 401 +GDP D T GP I + + ++ +++ GAK+ GG G + T+ V Sbjct: 321 KMGDPKDPSTFVGPMISESESRRLSGWMDAAVAAGAKIVAGGKV---DGAMFEATLLENV 377 Query: 402 TDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESG 461 + + ++E FGP+ + KF ++ + R N +D+GL A VFT +L + LE G Sbjct: 378 GRDQDLYRKEAFGPIAILEKFDRFDDALARVNDSDFGLQAGVFTDSLAHTQQAWDELEVG 437 Query: 462 TVWINCYNALYAQ-APFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 V IN + P+GG K SG GRE YA+ + TE + + ++ Sbjct: 438 GVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTEPRLLVVR 483 >5U0M-A nrPDB Length = 497 Score = 433 bits (1115), Expect = e-122, Method: Composition-based stats. Identities = 142/485 (29%), Positives = 225/485 (46%), Gaps = 13/485 (2%) Query: 32 TKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 ++I+ W G F + P T E + + DVD AV A+ AF WRR Sbjct: 12 GNVYIDGLWLPGH-GAPFESVQPVTGETVWDGNAASLEDVDAAVREARKAFL---AWRRK 67 Query: 92 DALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI 151 R ++ +L+E ++ LA ++TGKP + ++ + + ++ Sbjct: 68 SLAERQAVIEAFGELLEANKEELAHQIGLETGKPLWESRT-EVAAMMGKIPISVKAYNER 126 Query: 152 QGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPL 211 G T RH P GV P+NFP + + PAL GNT+V KP+E TP Sbjct: 127 TGHTESDVAGGHAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPG 186 Query: 212 TALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR 271 A L ++AG P GV+N+V G G G ++ H I+ + FTGS+ VG L+ E Sbjct: 187 VAELTVRLWEKAGLPDGVINLVQG-GSDTGKCLARHSLIDGLFFTGSSTVGHLLHEQFGG 245 Query: 272 SNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY-SEF 330 K + LE+GG NP IV +DLD AV A Q F + GQ CT A R+ V + EF Sbjct: 246 QPEKILALEMGGNNPLIVQNVSDLDGAVHHALQSAFLSAGQRCTCARRLLVPKGKKGDEF 305 Query: 331 VRRSVEYAKKRPVGD-PFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDK 389 + R VE A + V + D + G I + +++L+ + ++GA ++ Sbjct: 306 LARLVEVAARITVAEFDADPQPFMGSVISAEAANQLLKAQAAMLEKGATSLLEMKQLKPD 365 Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLD 449 + P + + + +E FGP+ + ++K +E ++ AN+T YGL+A + + + Sbjct: 366 TGLLSPGIVD--ATGIELEDQEFFGPLLTVYRYKGFDEALELANNTRYGLSAGILSDDRK 423 Query: 450 KALKLASALESGTVWIN-CYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 +L + +G V N + APFGG SGN R YA A+Y +++ G Sbjct: 424 LYNRLVEEVRAGIVNWNRPLTGASSAAPFGGVGASGNHRPSAYYA-ADYCAWPMASLEAG 482 Query: 509 D-KNP 512 + P Sbjct: 483 KSELP 487 >5J6B-A nrPDB Length = 485 Score = 427 bits (1099), Expect = e-120, Method: Composition-based stats. Identities = 141/480 (29%), Positives = 219/480 (45%), Gaps = 21/480 (4%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDAL 94 ++ NE + + + T + V D +D A+ AA A + P R L A Sbjct: 17 YLANEAVYAN--AELEVTDKYTGKVATRVALADASAIDAAIAAAVGAQK---PLRALPAF 71 Query: 95 SRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG- 153 R +L LA ++ GKP + ++ I T R A + +I+G Sbjct: 72 RRQAILEHCVARFRERFDELAQALCIEAGKPINDSKG-EVTRLIDTFRVAAEESVRIEGG 130 Query: 154 ----KTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQT 209 + P + + PIG C I+P+NFPL + K+APAL G VLKPA +T Sbjct: 131 LVNLEISPRAQGYSGYYKRVPIGPCSFISPFNFPLNLAAHKVAPALAAGCPFVLKPASRT 190 Query: 210 PLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAA 269 P+ AL +G ++ E P G +I+P ++ + ++FTGS VG +K+ A Sbjct: 191 PIGALIIGEVLAETDLPKGAFSILPAHRDGA-DLFTTDERFKLLSFTGSPTVGWELKKKA 249 Query: 270 SRSNLKRVTLELGGKNPCIVCADAD--LDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 + V LELGG IV AD LD VE G ++ GQ C R+ VY Sbjct: 250 GKKK---VVLELGGNAAAIVDADQREVLDYVVERLAFGAYYQSGQSCIGVQRIIAHADVY 306 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 + + + +GDP D T GP I + + ++ +E+ GAK+ GG Sbjct: 307 DALREKLIAKTRSLKMGDPKDPATFVGPMISESEARRLAGWMEAAVAAGAKIVAGGKV-- 364 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 G + T+ V + + ++E FGPV + +F ++ + R N +D+GL A VFT + Sbjct: 365 -DGAMFEATLLEGVGRDQDLYRKEAFGPVALLERFSDFDDALARVNDSDFGLQAGVFTDS 423 Query: 448 LDKALKLASALESGTVWINCYNALYAQ-APFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 L A + LE G V IN + P+GG K SG GRE YA+ + TE++ + ++ Sbjct: 424 LSHAQRAWDELEVGGVVINDVPSFRVDNMPYGGVKDSGLGREGIRYAIEDMTELRLMVVR 483 >4E4G-A nrPDB Length = 521 Score = 426 bits (1095), Expect = e-119, Method: Composition-based stats. Identities = 141/480 (29%), Positives = 226/480 (47%), Gaps = 15/480 (3%) Query: 34 IFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDA 93 FI+ + SG+ NP+T E V A + A W + Sbjct: 29 HFIDGKRVAGTSGRVSNIFNPATGEVQGTVALASDA---DLAAAVESAKAAQPKWAATNP 85 Query: 94 LSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 R R+ + L+ + LA + + + GK A D+ + + G + Sbjct: 86 QRRARVFMKFVQLLNDNMNELAEMLSREHGKTIDDAKG-DIVRGLEVCEFVIGIPHLQKS 144 Query: 154 K-TIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLT 212 + T + ++ +P+G+ ITP+NFP ++ +W APA+ CGN +LKP+E+ P Sbjct: 145 EFTEGAGPGIDMYSIRQPVGIGAGITPFNFPGMIPMWMFAPAIACGNAFILKPSERDPSV 204 Query: 213 ALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS 272 + L L+ EAG P G++N+V G V AI +HP I ++F GST + + V A+ Sbjct: 205 PIRLAELMIEAGLPAGILNVVNGDKGAV-DAILTHPDIAAVSFVGSTPIARYVYGTAA-M 262 Query: 273 NLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAAS-RVFVEEQVYSEFV 331 N KR G KN I+ DADLD A + + G+ C A S V V E+ + + Sbjct: 263 NGKRAQCFGGAKNHMIIMPDADLDQAANALIGAGYGSAGERCMAISVAVPVGEETANRLI 322 Query: 332 RRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME---- 387 + V + +G D K + GP + ++ +I LI+SG ++GAKL G + Sbjct: 323 DKLVPMVESLRIGPYTDEKADMGPVVTKEAEQRIRSLIDSGIEQGAKLVVDGRDFKLQGY 382 Query: 388 DKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKN 447 + G FI +F +VT +M I K EIFGPV +++ ++ EE + +YG A++T++ Sbjct: 383 ENGHFIGGCLFDDVTPDMDIYKTEIFGPVLSVVRARNYEEALSLPMKHEYGNGVAIYTRD 442 Query: 448 LDKALKLASALESGTVWINCY-NALYAQAPFGGFKMSGNGR--ELGEYALAEYTEVKTVT 504 D A AS + G V +N A FGG+K S G + G ++ +T KT+T Sbjct: 443 GDAARDFASRINIGMVGVNVPIPVPLAYHSFGGWKSSSFGDLNQHGTDSIKFWTRTKTIT 502 >1UXV-A nrPDB Length = 501 Score = 421 bits (1082), Expect = e-118, Method: Composition-based stats. Identities = 152/487 (31%), Positives = 237/487 (48%), Gaps = 24/487 (4%) Query: 35 FINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPW--RRLD 92 ++ EW SG++ +P I +V + +V++ ++ V F+RG W R + Sbjct: 22 YLAGEW--GGSGQEIEVKSPIDLATIAKVISPSREEVERTLD---VLFKRGR-WSARDMP 75 Query: 93 ALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQ 152 R +L + AD++ER+ A + M+ GKP A +++ + LR KI Sbjct: 76 GTERLAVLRKAADIIERNLDVFAEVLVMNAGKP-KSAAVGEVKAAVDRLRLAELDLKKIG 134 Query: 153 GKTIPTDDNV-----VCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAE 207 G IP D R EP+GV AITP+N+PL V K+ + GN +V+KP+ Sbjct: 135 GDYIPGDWTYDTLETEGLVRREPLGVVAAITPFNYPLFDAVNKITYSFIYGNAVVVKPSI 194 Query: 208 QTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKE 267 PL A + +AGFPP + ++ G I + ++ ++FTGSTEVG+ V + Sbjct: 195 SDPLPAAMAVKALLDAGFPPDAIALLNLPGKEA-EKIVADDRVAAVSFTGSTEVGERVVK 253 Query: 268 AASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY 327 +K+ +ELGG +P IV DADLDLA + +G++ GQ C A V E VY Sbjct: 254 VGG---VKQYVMELGGGDPAIVLEDADLDLAADKIARGIYSYAGQRCDAIKLVLAERPVY 310 Query: 328 SEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME 387 + V + VGDP D + GP I D+++ IE ++G ++ GG + Sbjct: 311 GKLVEEVAKRLSSLRVGDPRDPTVDVGPLISPSAVDEMMAAIEDAVEKGGRVLAGGRRLG 370 Query: 388 DKGLFIKPTVFSEVTD---NMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVF 444 +++PT+ D +M + K E+F PV ++ K +++ I+ AN YGL AAVF Sbjct: 371 PT--YVQPTLVEAPADRVKDMVLYKREVFAPVALAVEVKDLDQAIELANGRPYGLDAAVF 428 Query: 445 TKNLDKALKLASALESGTVWINCYN-ALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTV 503 +++ K + LE G ++IN PFGG K SG RE YA+ T KT+ Sbjct: 429 GRDVVKIRRAVRLLEVGAIYINDMPRHGIGYYPFGGRKKSGVFREGIGYAVEAVTAYKTI 488 Query: 504 TIKLGDK 510 K Sbjct: 489 VFNYKGK 495 >3SZA-A nrPDB Length = 469 Score = 419 bits (1078), Expect = e-117, Method: Composition-based stats. Identities = 120/442 (27%), Positives = 204/442 (46%), Gaps = 20/442 (4%) Query: 71 VDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAF 130 + +AV+ A+ AF G R R + L L L++ L D K +A+ Sbjct: 20 ISEAVKRARAAFSSG---RTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAY 76 Query: 131 FIDLEGCIRTLRYFA----GWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLM 186 + ++ + + Y WA + P + EP+GV I WN+P + Sbjct: 77 YEEVVYVLEEIEYMIQKLPEWAADEPVEKTPQTQQDELYIHSEPLGVVLVIGTWNYPFNL 136 Query: 187 LVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISS 246 + + A+ GN +VLKP+E + A L ++I + + ++ G P + Sbjct: 137 TIQPMVGAIAAGNAVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE 195 Query: 247 HPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGV 306 + + I +TGST VGK++ AA++ +L VTLELGGK+PC V + DLD+A G Sbjct: 196 --RFDHILYTGSTGVGKIIMTAAAK-HLTPVTLELGGKSPCYVDKNCDLDVACRRIAWGK 252 Query: 307 FFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKIL 366 F N GQ C A + + + ++ V + + K+ G+ + G I + F +++ Sbjct: 253 FMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEF-YGEDAKKSRDYGRIISARHFQRVM 311 Query: 367 ELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIE 426 LI EG K+ GG+ + +I PT+ ++V + +EEIFGPV PI+ +S+E Sbjct: 312 GLI-----EGQKVAYGGTG-DAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLE 365 Query: 427 EVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC--YNALYAQAPFGGFKMSG 484 E I+ N + L +F+ N K+ + SG V N + PFGG SG Sbjct: 366 EAIQFINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSG 425 Query: 485 NGRELGEYALAEYTEVKTVTIK 506 G G+ + ++ ++ ++ Sbjct: 426 MGSYHGKKSFETFSHRRSCLVR 447 >3V9H-A nrPDB Length = 566 Score = 416 bits (1071), Expect = e-117, Method: Composition-based stats. Identities = 143/536 (26%), Positives = 244/536 (45%), Gaps = 36/536 (6%) Query: 1 MATANGA---VENGQPDRKPPALPRPIRNLEVKFTKI--FINNEWHESKSGKKFATCNPS 55 + AN G P+R AL + +++L+ + I + +E S ++ + Sbjct: 33 LKVANEPVLAFTQGSPERD--ALQKALKDLKGRMEAIPCVVGDEEV-WTSDVQYQVSPFN 89 Query: 56 TREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVER-DRATL 114 ++ + DK ++KA+EAA A + W R ++ + AD++ RA + Sbjct: 90 HGHKVAKFCYADKSLLNKAIEAALAARKE---WDLKPIADRAQIFLKAADMLSGPRRAEI 146 Query: 115 AALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK---TIPTDDNVVCFTRHEPI 171 A + GK + A I R+ A +A +++G+ ++P N + E Sbjct: 147 LAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLE-- 204 Query: 172 GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVN 231 G AI+P+NF + APAL GN ++ KP++ L + + +++EAG PP ++ Sbjct: 205 GFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQ 263 Query: 232 IVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASR-----SNLKRVTLELGGKNP 286 VP GP G ++S + I FTGS K + + ++ R+ E GGKN Sbjct: 264 FVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNF 323 Query: 287 CIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDP 346 V AD++ V + F GQ C+A +R++V ++ + R +E + VGDP Sbjct: 324 HFVHRSADVESVVSGTLRSAFEYGGQKCSACARLYVPHSLWPQIKGRLLEEHSRIKVGDP 383 Query: 347 F-DVKTEQGPQIDQKQFDKILELIESGKKEGA-KLECGGSAMEDKGLFIKPTVFSEVTDN 404 D T ID K F +I + +E + + + GG + G F++P + Sbjct: 384 AEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQ 443 Query: 405 MRIAKEEIFGPVQPILKFKSI--EEVIKRANS-TDYGLTAAVFTKNLDKALKLASALE-- 459 I KEEIFGPV + + +E ++ +S T YGLT AVF+++ D + L Sbjct: 444 EPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNA 503 Query: 460 SGTVWINC--YNALYAQAPFGGFKMSG-NGRELGEYALAEYTE---VKTVTIKLGD 509 +G +IN ++ Q PFGG + SG N + G + + +T +K LGD Sbjct: 504 AGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGD 559 >6DBB-A nrPDB Length = 511 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 128/484 (26%), Positives = 227/484 (46%), Gaps = 25/484 (5%) Query: 46 GKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLAD 105 G +P + + D ++ ++AA AF + WR + A RG L+ + Sbjct: 27 GNALTARSPLDGATLATLAVDTPADAERKIDAAHDAFLK---WRTVPAPVRGELVRVFGN 83 Query: 106 LVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDD-NVVC 164 ++ +A L L T++ GK +++ I + G + ++ G TI ++ Sbjct: 84 VLREHKAELGRLVTLEAGK-ITSEGLGEVQEMIDICDFAVGLSRQLYGLTIASERPGHRM 142 Query: 165 FTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA- 223 PIGVCG I+ +NFP+ + W A A CG+++V KP+E+TPLTA+ L+++A Sbjct: 143 METWHPIGVCGVISAFNFPVAVWAWNAALAFVCGDSVVWKPSEKTPLTAIACHVLLQKAL 202 Query: 224 --------GF-PPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNL 274 G P + +V G VG +++ ++ ++ TGS +G+ V + S+ L Sbjct: 203 REFEKTHPGVAPAELGQLVLGM-RDVGEVLTASKKVPVVSATGSVRMGQEVAKVLSQ-RL 260 Query: 275 KRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRS 334 R LELGG N IV ADLDL V GQ CT R+ V + + + R Sbjct: 261 ARGILELGGNNGMIVAPSADLDLVVRAVTFAAVGTAGQRCTTLRRLIVHRSLVEQLLPRI 320 Query: 335 VEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME---DKGL 391 + VG+P + T GP +D+ FD + + + +++G +++ GG ++ Sbjct: 321 EKAYASVKVGNPLEEGTLVGPLVDRASFDAMQKALADAREQGGEVK-GGERVDVGHADAY 379 Query: 392 FIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKA 451 +++P + + + + E F P+ ++ + + ++ I N+ GL++A+FT ++ +A Sbjct: 380 YVRPAIV-RMPKQSAVVERETFAPILYVMVYDNFDDAIDVHNAVPQGLSSAIFTNDMREA 438 Query: 452 LKL--ASALESGTVWINC-YNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLG 508 + A+ + G V +N + FGG K +G GRE G A Y T TI Sbjct: 439 EQFMSAAGSDCGIVNVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKAYMRRATNTINYS 498 Query: 509 DKNP 512 + P Sbjct: 499 RQLP 502 >4LGZ-A nrPDB Length = 563 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 144/537 (26%), Positives = 243/537 (45%), Gaps = 38/537 (7%) Query: 1 MATANGA---VENGQPDRKPPALPRPIRNLEVKFTKI--FINNEWHESKSGKKFATCNPS 55 + AN G P+R AL + +++L+ + I + +E S ++ + Sbjct: 30 LKVANEPILAFSQGSPERD--ALQKALKDLKGQTEAIPCVVGDEEV-WTSDIQYQLSPFN 86 Query: 56 TREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVE--RDRAT 113 ++ + DK +++A++AA A + W R ++ + AD++ R Sbjct: 87 HAHKVAKFCYADKALLNRAIDAALAARKE---WDLKPMADRAQVFLKAADMLSGPRRAEV 143 Query: 114 LAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGK---TIPTDDNVVCFTRHEP 170 LA GK + A I R+ A +A +++G+ ++P N + E Sbjct: 144 LAKTMV-GQGKTVIQAEIDAAAELIDFFRFNAKFAVELEGEQPISVPPSTNHTVYRGLE- 201 Query: 171 IGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVV 230 G AI+P+NF + APAL GN ++ KP++ L + + +++EAG PP ++ Sbjct: 202 -GFVAAISPFNFTAIGGNLAGAPALM-GNVVLWKPSDTAMLASYAVYRILREAGLPPNII 259 Query: 231 NIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRS-----NLKRVTLELGGKN 285 VP GPT G ++S + I FTGS K + +++ R+ E GGKN Sbjct: 260 QFVPADGPTFGDTVTSSEHLCGINFTGSVPTFKHLWRQVAQNLDRFRTFPRLAGECGGKN 319 Query: 286 PCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGD 345 V + AD+D V + F GQ C+A SR++V + ++ + R +E + VGD Sbjct: 320 FHFVHSSADVDSVVSGTLRSAFEYGGQKCSACSRLYVPKSLWPQIKGRLLEEHSRIKVGD 379 Query: 346 PF-DVKTEQGPQIDQKQFDKILELIESGKKEGA-KLECGGSAMEDKGLFIKPTVFSEVTD 403 P D T ID K F +I + +E + + + GG E G +++P + Sbjct: 380 PAEDFGTFFSAVIDAKAFARIKKWLEHARSSPSLSILAGGQCNESVGYYVEPCIIESKDP 439 Query: 404 NMRIAKEEIFGPVQPILKFKSIE--EVIKRANS-TDYGLTAAVFTKNLDKALKLASALE- 459 I KEEIFGPV + + + E +K +S T YGLT AVF ++ + L Sbjct: 440 QEPIMKEEIFGPVLTVYVYPDDKYRETLKLVDSTTSYGLTGAVFAQDKAIVQEATRMLRN 499 Query: 460 -SGTVWINC--YNALYAQAPFGGFKMSG-NGRELGEYALAEYTE---VKTVTIKLGD 509 +G +IN ++ Q PFGG + SG N + G + + +T +K LGD Sbjct: 500 AAGNFYINDKSTGSVVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGD 556 >4KNA-A nrPDB Length = 495 Score = 409 bits (1052), Expect = e-114, Method: Composition-based stats. Identities = 138/462 (29%), Positives = 214/462 (46%), Gaps = 10/462 (2%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 T++FI+ W + G FA+ NP T E++ E DV++AV +A+ AF + W Sbjct: 9 MTELFIDGAWVDGA-GPVFASRNPGTNERVWEGASASADDVERAVASARRAF---AAWSA 64 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 LD +R ++ + A L+ + LA + +TGKP A + + ++ Sbjct: 65 LDLDARCTIVKRFAALLVERKEALATMIGRETGKPLWEARTEVASMAAKVDISITAYHER 124 Query: 151 IQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 K P D V RH P GV P+NFP + + PAL GNT+V KP+E P Sbjct: 125 TGEKRAPMADGVAVL-RHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNTVVFKPSELAP 183 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 A + ++AG P GV+N+V G G A+++H QI+ + FTGS++ G L+ + Sbjct: 184 GVARATVEIWRDAGLPAGVLNLVQGEK-DTGVALANHRQIDGLFFTGSSDTGTLLHKQFG 242 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY-SE 329 + LE+GG NP +V D+D AV A Q F + GQ CT A R+ V + Sbjct: 243 GRPEIVLALEMGGNNPLVVAEVEDIDAAVHHAIQSAFLSAGQRCTCARRILVPRGAFGDR 302 Query: 330 FVRRSVEYAKKRPVG-DPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED 388 FV R + A K D + G I + +++ GA + Sbjct: 303 FVARLADVASKITASVFDADPQPFMGAVISARAASRLVAAQARLVGLGASPIIEMKQRDP 362 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 F+ + +VT+ + EE FGP+ I+++ +++ I RAN T +GL+A + + Sbjct: 363 ALGFVNAAIL-DVTNVRELPDEEHFGPLAQIVRYTDLDDAIARANDTAFGLSAGLLADDE 421 Query: 449 DKALKLASALESGTVWIN-CYNALYAQAPFGGFKMSGNGREL 489 A+ +G V N N + APFGG SGN R Sbjct: 422 QAWHTFRRAIRAGIVNWNRPTNGASSAAPFGGAGRSGNHRPS 463 >3JU8-A nrPDB Length = 490 Score = 405 bits (1041), Expect = e-113, Method: Composition-based stats. Identities = 128/462 (27%), Positives = 200/462 (43%), Gaps = 10/462 (2%) Query: 31 FTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRR 90 + +I +W + G+ + +P + + D VD AV AA+ AF W R Sbjct: 5 MSTHYIAGQWL-AGQGETLESLDPVGQGVVWSGRGADATQVDAAVCAAREAF---PAWAR 60 Query: 91 LDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 R LL + A ++ LA + +TGKP + + + ++ Sbjct: 61 RPLEQRIELLERFAATLKSRADELARVIGEETGKPLWESATEVTSMVNKVAISVQAFRER 120 Query: 151 IQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTP 210 K+ P D RH+P GV P+NFP + + PAL GN +V KP+E TP Sbjct: 121 TGEKSGPLAD-ATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNCVVFKPSELTP 179 Query: 211 LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAAS 270 A +AG P GV+N+V G G G A+++H ++ + FTGS+ G L+ Sbjct: 180 KVAELTLKAWIQAGLPAGVLNLVQG-GRETGVALAAHRGLDGLFFTGSSRTGNLLHSQFG 238 Query: 271 RSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVY-SE 329 K + LE+GG NP +V ADLD AV Q F + GQ CT A R+ V + + Sbjct: 239 GQPQKILALEMGGNNPLVVEEVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDA 298 Query: 330 FVRRSVEYAKKRPVGD-PFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMED 388 + R V + VG G I + +L+ E +GA+ + D Sbjct: 299 LLARLVAVSATLRVGRFDEQPAPFMGAVISLSAAEHLLKAQEHLIGKGAQPLLAMTQPID 358 Query: 389 KGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 + P + +V+ EE FGP+ ++++ I+ AN+T YGL A + + + Sbjct: 359 GAALLTPGIL-DVSAVAERPDEEFFGPLLQVIRYSDFAAAIREANATQYGLAAGLLSDSR 417 Query: 449 DKALKLASALESGTVWIN-CYNALYAQAPFGGFKMSGNGREL 489 ++ + +G V N + APFGG SGN R Sbjct: 418 ERFEQFLVESRAGIVNWNKQLTGAASSAPFGGIGASGNHRPS 459 >1AD3-A nrPDB Length = 452 Score = 403 bits (1035), Expect = e-112, Method: Composition-based stats. Identities = 121/443 (27%), Positives = 205/443 (46%), Gaps = 22/443 (4%) Query: 71 VDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAF 130 + V+ A+ AF G + R + L L ++ + +++ D GK ++ Sbjct: 3 ISDTVKRAREAFNSG---KTRSLQFRIQQLEALQRMINENLKSISGALASDLGKNEWTSY 59 Query: 131 FIDLEGCIR----TLRYFAGWA-DKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLL 185 + ++ + T++ WA D+ KT T + + + EP+GV I WN+P Sbjct: 60 YEEVAHVLEELDTTIKELPDWAEDEPVAKTRQTQQDDL-YIHSEPLGVVLVIGAWNYPFN 118 Query: 186 MLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAIS 245 + + + A+ GN ++LKP+E + A L +LI + + +V G P + Sbjct: 119 LTIQPMVGAVAAGNAVILKPSEVSGHMADLLATLIPQY-MDQNLYLVVKGGVPETTELLK 177 Query: 246 SHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQG 305 + + I +TGST VGK+V AA++ +L VTLELGGK+PC V D DLD+A G Sbjct: 178 E--RFDHIMYTGSTAVGKIVMAAAAK-HLTPVTLELGGKSPCYVDKDCDLDVACRRIAWG 234 Query: 306 VFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKI 365 F N GQ C A + + + ++ V + + K G+ + G I+ + F ++ Sbjct: 235 KFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKDF-YGEDAKQSRDYGRIINDRHFQRV 293 Query: 366 LELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSI 425 LI++ K G + +I PT+ +V + +EEIFGPV PI+ +S+ Sbjct: 294 KGLIDNQK------VAHGGTWDQSSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSL 347 Query: 426 EEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC--YNALYAQAPFGGFKMS 483 EE I+ N + L VF+ N K+ + SG V N + PFGG S Sbjct: 348 EEAIQFINQREKPLALYVFSNNEKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNS 407 Query: 484 GNGRELGEYALAEYTEVKTVTIK 506 G G G+ + ++ ++ +K Sbjct: 408 GMGAYHGKKSFETFSHRRSCLVK 430 >4I3V-A nrPDB Length = 488 Score = 396 bits (1017), Expect = e-110, Method: Composition-based stats. Identities = 141/491 (28%), Positives = 226/491 (46%), Gaps = 26/491 (5%) Query: 27 LEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGS 86 + V+ + I + + + P + V G +A A Sbjct: 11 IAVRHEPMRIAGRLVD--TDDRVEVRYPWNDTVVGTVPAGRAEHAREAFAIAAAYQ---- 64 Query: 87 PWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAG 146 +L R ++L A+ + + ++ + T++ G + + ++ Sbjct: 65 --PKLTRYERQKILLATAEALAARKEEISDVITLELGISKADSLY-EVGRAFDVFTLAGQ 121 Query: 147 WADKIQGKTI-----PTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTM 201 + G+ P FT EP+ AITP+N PL M+ K+APA+ N + Sbjct: 122 MCIRDDGEIFSCDLTPHGKARKIFTMREPLTAISAITPFNHPLNMVAHKVAPAIATNNCV 181 Query: 202 VLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEV 261 V+KP E TP+TAL L ++ EAG PP ++++V G+ +G + ++P ++ + FTGS V Sbjct: 182 VVKPTELTPMTALLLADILYEAGLPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPV 241 Query: 262 GKLVKEAASRSNLKRVTLELGGKNPCIV---CADADLDLAVECAHQGVFFNQGQCCTAAS 318 GKL+ A+ ++ KR LELGG +P I+ +D DL A + A G N GQ CTA Sbjct: 242 GKLI---AANAHYKRQVLELGGNDPLIILNDLSDDDLARAADLAVAGATKNSGQRCTAVK 298 Query: 319 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 R+ +E V FV +E AK+ GDP D T+ G I +K E + +EGA Sbjct: 299 RILCQESVADRFVPLVLERAKRLRFGDPMDRSTDLGTVIHEKAAALFEERVMRAAEEGAD 358 Query: 379 LECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEV-IKRANSTDY 437 + G + P V V + EE FGP+ PI++ ++ I +NST + Sbjct: 359 ILYH---PGRSGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDDDDATITLSNSTAF 415 Query: 438 GLTAAVFTKNLDKALKLASALESGTVWI-NCYNALYAQAPFGGFKMSGNG-RELGEYALA 495 GL++ V T + + K + L+ GTV I +PFGG K SGNG +E A+ Sbjct: 416 GLSSGVCTNDYRRMQKYIAGLKVGTVNIWEVPGYRIEMSPFGGIKDSGNGYKEGVIEAMK 475 Query: 496 EYTEVKTVTIK 506 +T VKT ++ Sbjct: 476 SFTNVKTFSLP 486 >4QGK-A nrPDB Length = 461 Score = 381 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 114/439 (25%), Positives = 198/439 (45%), Gaps = 22/439 (5%) Query: 75 VEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDL 134 V + AF G R R + L L +V+ + D K + + ++ Sbjct: 6 VRRVRQAFLSG---RSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEV 62 Query: 135 EGCIRTLRYFAGWADKIQGKTIPTDDNVV-----CFTRHEPIGVCGAITPWNFPLLMLVW 189 + + + + P NV+ + + +P+GV I WN+P ++ + Sbjct: 63 ITVLGEIDFMLENLPEWV-TAKPVKKNVLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQ 121 Query: 190 KLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQ 249 L A+ GN +++KP+E + TA L L+ + + ++ G + + Sbjct: 122 PLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLK--QR 178 Query: 250 INKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFN 309 + I +TG+T VGK+V EAA++ +L VTLELGGK+PC + D DLD+ G + N Sbjct: 179 FDHIFYTGNTAVGKIVMEAAAK-HLTPVTLELGGKSPCYIDKDCDLDIVCRRITWGKYMN 237 Query: 310 QGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELI 369 GQ C A + E + ++ V + E K+ G+ + I+ + F +IL L+ Sbjct: 238 CGQTCIAPDYILCEASLQNQIVWKIKETVKEF-YGENIKESPDYERIINLRHFKRILSLL 296 Query: 370 ESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVI 429 EG K+ GG ++ +I PTV ++V ++ +EEIFGP+ PI+ K+++E I Sbjct: 297 -----EGQKIAFGGET-DEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAI 350 Query: 430 KRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINC--YNALYAQAPFGGFKMSGNGR 487 N + L VF+ N ++ SG V N + PFGG SG G Sbjct: 351 NFINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGA 410 Query: 488 ELGEYALAEYTEVKTVTIK 506 G+++ ++ + +K Sbjct: 411 YHGKHSFDTFSHQRPCLLK 429 >4H7N-A nrPDB Length = 474 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 138/469 (29%), Positives = 215/469 (45%), Gaps = 21/469 (4%) Query: 47 KKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADL 106 K NP T + + + + A+ A R W+ L R L Q Sbjct: 6 KTIEVRNPRTGKFDYVIIPPPPRLLAQQCNRARRAQSR---WQELGVEGRITTLQQWKQA 62 Query: 107 VERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKI-QGKTIPTDDNVVCF 165 + R L DTG+ L ++++ + ++ + G A ++ Q T + Sbjct: 63 ILSRREQLTEALVNDTGR--LSITVLEIDSFLASIDRWCGLAPELLQTSAKNTSIPFIAL 120 Query: 166 TRH-EPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAG 224 + P + G I+PWNFPL + + PAL G +V+KP+E P ++ L+ Sbjct: 121 QQSLVPYPLVGVISPWNFPLTLSMIDTIPALLAGCAVVVKPSEIAP---RFVAPLLMALN 177 Query: 225 FPP---GVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLEL 281 P V+ V G G GA + ++ ++ + FTGS G+ V E A+R LEL Sbjct: 178 TVPELRDVLIFVEGGG-ETGANLINY--VDFVCFTGSVATGREVAETAAR-RFIPAYLEL 233 Query: 282 GGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKR 341 GGK+P IV A+L+LA G N GQ C + R++V E + EF + + A + Sbjct: 234 GGKDPAIVLESANLELATSAILWGAVVNTGQSCLSIERIYVAESKFEEFYHQLIAKAHRL 293 Query: 342 PVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAME-DKGLFIKPTVFSE 400 + P GP I +KQ I + I ++GA + CGG E G + +PTV + Sbjct: 294 QLAYPLVEDGAIGPIIAEKQAGIINDHILDAVEKGAVIHCGGKVEELGGGWWCRPTVMTN 353 Query: 401 VTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALES 460 V +M++ EE FGP+ P++ F +EE + AN T YGL+AAVF + D+ALK+A L + Sbjct: 354 VNHSMKVMTEETFGPIMPVMPFPDVEEAVYLANDTIYGLSAAVFAGSEDEALKVARQLNA 413 Query: 461 GTVWINC--YNALYAQAPFGGFKMSGN-GRELGEYALAEYTEVKTVTIK 506 G + IN A+ + F SG G +G L + + IK Sbjct: 414 GAISINDAALTAMMHEGEKNAFNFSGLGGSRVGAAGLKRFLRKQAFLIK 462 >4OE4-A nrPDB Length = 580 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 133/509 (26%), Positives = 224/509 (44%), Gaps = 41/509 (8%) Query: 34 IFINNEWH-ESKSGKKFATCNPST-REQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRL 91 + IN E ++ F NP+ ++ + V + + DV + A + A W L Sbjct: 62 LVINGERIYDNNERALFPQTNPANHQQVLANVTQATEKDV---MNAVKAAKDAKKDWYNL 118 Query: 92 DALSRGRLLHQLADLVE-RDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADK 150 R + + ADL+ + R + A + GK A + RY+ +A Sbjct: 119 PFYDRSAIFLKAADLISTKYRYDMLAATMLGQGKNVYQAEIDCITELSDFFRYYVKYASD 178 Query: 151 IQGKT-IPTDDNVVCFTRHEPI-GVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQ 208 + + + + D + P+ G A++P+NF + APAL GNT+V KP++ Sbjct: 179 LYAQQPVESADGTWNKAEYRPLEGFVYAVSPFNFTAIAANLIGAPALM-GNTVVWKPSQT 237 Query: 209 TPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEA 268 L+ L ++++EAG P GV+N +PG V + + + FTGST V K + Sbjct: 238 AALSNYLLMTVLEEAGLPKGVINFIPGDPVQVTDQVLADKDFGALHFTGSTNVFKSLYGK 297 Query: 269 -------ASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVF 321 + R+ E GGKN +V A++ AV +G F QGQ C+AASR++ Sbjct: 298 IQSGVVEGKYRDYPRIIGETGGKNFHLVHPSANISHAVLSTIRGTFEFQGQKCSAASRLY 357 Query: 322 VEEQVYSEFVR------RSVEYAKKRPVGDPFDVKT---EQGPQIDQKQFDKILELIESG 372 + E EF+ +S P GP I ++ FDK++++IE Sbjct: 358 LPESKSEEFLSDMFGILQSQNVVPMNTSASPISGGNLRGFMGPVIHEQSFDKLVKVIEDA 417 Query: 373 KKEG-AKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIE----- 426 KK+ ++ GG + +G F+ PTV + E FGP+ + ++ E Sbjct: 418 KKDPELEILYGGQYDKSQGWFVGPTVIKAKRPDHPYMSTEFFGPILTVYEYPDTEFNEIC 477 Query: 427 EVIKRANSTDYGLTAAVFTKNLDKALKLASALE--SGTVWIN--CYNALYAQAPFGGFKM 482 ++I N++ Y LT A+F K+ L+ +G +IN C A+ +Q FGG +M Sbjct: 478 DIID--NTSQYALTGAIFAKDRKAIEYADEKLKFSAGNFYINDKCTGAVVSQQWFGGARM 535 Query: 483 SGNGRELGEYALAEYTEVKTVTIKLGDKN 511 SG + G + + V+I+ +N Sbjct: 536 SGTDDKAGGPNILS----RFVSIRNTKEN 560 >5UCD-A nrPDB Length = 457 Score = 358 bits (920), Expect = 3e-99, Method: Composition-based stats. Identities = 131/436 (30%), Positives = 205/436 (47%), Gaps = 22/436 (5%) Query: 77 AAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEG 136 +AQ A+ D R + L +L + V ++ L + D GKP ++ Sbjct: 35 SAQKAYFATRA--TADVGFRKQSLERLKEAVINNKEALYSALAEDLGKPKDVVDLAEIGA 92 Query: 137 CIRTLRYFAGWADKIQGK-TIPTDDNV---VCFTRHEPIGVCGAITPWNFPLLMLVWKLA 192 + + + D+ ++P+ D + C+ EP GV I P+N+P+ + + L Sbjct: 93 VLHEIDFALAHLDEWVAPVSVPSPDIIAPSECYVVQEPYGVTYIIGPFNYPVNLTLTPLI 152 Query: 193 PALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINK 252 A+ GNT ++KP+E TP T+ + +I EA F P V ++ G G + + S P + Sbjct: 153 GAIIGGNTCIIKPSETTPETSAVIEKIIAEA-FAPEYVAVIQG-GRDENSHLLSLP-FDF 209 Query: 253 IAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQ 312 I FTGS VGK+V +AA++ +L V LELGGK P IV DADLD V G F N GQ Sbjct: 210 IFFTGSPNVGKVVMQAAAK-HLTPVVLELGGKCPLIVLPDADLDQTVNQLMFGKFINSGQ 268 Query: 313 CCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESG 372 A ++V V + R VE K G + ++Q +++ L+E+ Sbjct: 269 TXIAPDYLYVHYSVKDALLERLVERVKTE-----LPEINSTGKLVTERQVQRLVSLLEA- 322 Query: 373 KKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRA 432 +G L GS + + TV V N + EE+FGP+ P+L+F S+ I + Sbjct: 323 -TQGQVLV--GSQADVSKRALSATVVDGVEWNDPLMSEELFGPILPVLEFDSVRTAIDQV 379 Query: 433 NS-TDYGLTAAVFTKNLDKALKLASALESGTVWINCY--NALYAQAPFGGFKMSGNGREL 489 N L VF K++D A + + ++SG +N +A PFGG SG G Sbjct: 380 NKHHPKPLAVYVFGKDMDVAKGIINQIQSGDAQVNGVMLHAFSPYLPFGGIGASGMGEYH 439 Query: 490 GEYALAEYTEVKTVTI 505 G ++ +T K+V I Sbjct: 440 GHFSYLTFTHKKSVRI 455 >4IDS-A nrPDB Length = 563 Score = 332 bits (851), Expect = 3e-91, Method: Composition-based stats. Identities = 129/519 (24%), Positives = 202/519 (38%), Gaps = 23/519 (4%) Query: 4 ANGAVENG---QPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQI 60 AN V + P+R I H G++ P Sbjct: 31 ANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGR-HRMGDGERIDVVQPHRHA-- 87 Query: 61 CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERD-RATLAALET 119 + A A + A S W L R + + ADL+ R +AA Sbjct: 88 ARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWREKIAAATM 147 Query: 120 MDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPI-GVCGAIT 178 + K A + I R+ +A +I + + + P+ G AIT Sbjct: 148 LGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLDGFVYAIT 207 Query: 179 PWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGP 238 P+NF + APAL GNT++ KP+ L A L++ AG PPGV+N+V G G Sbjct: 208 PFNFTSIAGNLPTAPALM-GNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINLVTGDGF 266 Query: 239 TVGAAISSHPQINKIAFTGSTEVGKLVKEAASR-----SNLKRVTLELGGKNPCIVCADA 293 V + P++ I FTGST + + + R+ E GGK+ + A A Sbjct: 267 AVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFVVAHASA 326 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQ 353 D+ +G F QGQ C+A SR F+ V+ + A + GD D+ Sbjct: 327 RPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDITDLSNYG 386 Query: 354 GPQIDQKQFDKILELIESGKKEGA-KLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEI 412 G IDQ+ F K ++ IE K A + GG + +G F++PTV E Sbjct: 387 GALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDESFVIEY 446 Query: 413 FGPVQPILKFKSI--EEVIKRAN-STDYGLTAAVFTKNLDKALKLASALE--SGTVWINC 467 FGP+ + + E+++ + + Y LT AV + L L +G ++N Sbjct: 447 FGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAGNFYVND 506 Query: 468 --YNALYAQAPFGGFKMSG-NGRELGEYALAEYTEVKTV 503 A+ + PFGG + S N + L +T +++ Sbjct: 507 KPTGAVVGRQPFGGARGSDTNDKAGSPLNLLRWTSARSI 545 >5NNO-A nrPDB Length = 546 Score = 314 bits (804), Expect = 7e-86, Method: Composition-based stats. Identities = 122/456 (26%), Positives = 200/456 (43%), Gaps = 38/456 (8%) Query: 75 VEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDL 134 V + AF D R ++L L +LVE + D + +++ Sbjct: 21 VSKCREAFNDD---ANRDLKKRKQVLRSLLNLVEENTDEFCKAIHRDRRRHRDETVVMEI 77 Query: 135 EGCIRTLRYFAGWADKIQGKTIPTDDNVVCF----TRHEPIGVCGAITPWNFPLLMLVWK 190 + + D+ PT + ++EP+GV I WN+PLL+++ Sbjct: 78 LPLRNEVWHLIEHMDEYVKPVKPTMEGAAALDDCELQYEPLGVVLVIGTWNYPLLLILQP 137 Query: 191 LAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQI 250 L AL GNT V+KP+E P TA L L+ + VV IV G A + + Sbjct: 138 LLGALAAGNTAVIKPSELAPATAELLTKLLPKY-VSSDVVGIVNGGVSETTAVLKE--RF 194 Query: 251 NKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA--DLDLAVECAHQGVFF 308 + I +TGS V ++V AA++ +L VTLELGGK+P +V ++ + E G Sbjct: 195 DHILYTGSARVAEIVMAAAAK-HLTPVTLELGGKSPVVVDDTCADNMKVVAERIMWGKII 253 Query: 309 NQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGD----------------PFDVKTE 352 N GQ A V VE+ + S V E A+K +GD F +++ Sbjct: 254 NAGQTSIAPDYVVVEKSMESVLVDALAE-ARKAMLGDKFLKVLKGELLVKQKQQFLEESD 312 Query: 353 QGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEI 412 ++ F +++E + +G K+ GG A ++ L I PT+ + + + +EEI Sbjct: 313 YPRIVNASHFQRLMEFM-----KGGKVAVGGEA-DEATLTIAPTILTNIDPTHPVMQEEI 366 Query: 413 FGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGT--VWINCYNA 470 FGP+ P+L +++ ++++K NS + L VF+ N + S SG V +A Sbjct: 367 FGPILPVLTYENEKDILKIINSREKPLALYVFSNNKRFIRGVESRTSSGAVVVNDVVVHA 426 Query: 471 LYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIK 506 PFGG SG G G Y+ ++ + V + Sbjct: 427 GADGLPFGGVGRSGMGAYHGRYSFETFSHRRPVMRR 462 >2Y53-A nrPDB Length = 534 Score = 252 bits (643), Expect = 3e-67, Method: Composition-based stats. Identities = 109/484 (22%), Positives = 192/484 (39%), Gaps = 44/484 (9%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 + K + +W + +G +P T + V D+ +A A+ G+ R Sbjct: 6 ELLKNHVAGQWI-AGTGAGITLTDPVTGVALVRVSSEGL-DLARAFSFARE--DGGAALR 61 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 L R L + L++ R A+ T ++G + +D++G I TL Y+A Sbjct: 62 ALTYAQRAARLADIVKLLQAKRGDYYAIATANSG-TTRNDSAVDIDGGIFTLSYYAKLGA 120 Query: 150 KIQ---------GKTIPTDDNVVCFTRHEPI-GVCGAITPWNFPLLMLVWKLAPALCCGN 199 + +++ D + P GV I +NFP L K APAL G Sbjct: 121 SLGEVHALRDGSAESLSKDRSFSAQHVLSPTRGVALFINAFNFPSWGLWEKAAPALLSGV 180 Query: 200 TMVLKPAEQTP-LTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGS 258 +++KPA T LT + ++ PPG ++I+ G + I S + ++FTGS Sbjct: 181 PVIVKPATATAWLTQRMVADVVDAGILPPGALSIICGSSAGLLDQIRS---FDVVSFTGS 237 Query: 259 TEVGKLV-KEAASRSNLKRVTLELGGKNPCIVCADAD-----LDLAVECAHQGVFFNQGQ 312 + + A R+ ++ N I+CADA DL ++ + + GQ Sbjct: 238 ADTAATLRAHPAFVQRGARLNVQADSLNSAILCADATPDTPAFDLFIKEVVREMTVKSGQ 297 Query: 313 CCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESG 372 CTA R FV E + K VG+P + G + ++Q++ +L I + Sbjct: 298 KCTAIRRAFVPEAALEPVLEALKAKLAKITVGNPRNDAVRMGSLVSREQYENVLAGIAAL 357 Query: 373 KKEGAKLECGGSAME------DKGLFIKPTVF-SEVTDNMRIAKE-EIFGPVQPILKFK- 423 ++E A L SA+ + + P +F DN + + E+FGPV + ++ Sbjct: 358 REE-AVLAYDSSAVPLIDADANIAACVAPHLFVVNDPDNATLLHDVEVFGPVASVAPYRV 416 Query: 424 -------SIEEVIKRANSTDYGLTAAVFTKNLDKALKLASAL--ESGTVWINCYNALYAQ 474 + A L A++++ + +LA L G V + ++Q Sbjct: 417 TTDTNALPEAHAVALARRGQGSLVASIYSNDDAHLGRLALELADSHGRVHAISPSVQHSQ 476 Query: 475 APFG 478 G Sbjct: 477 TGHG 480 >3V4C-A nrPDB Length = 528 Score = 240 bits (612), Expect = 1e-63, Method: Composition-based stats. Identities = 112/474 (23%), Positives = 166/474 (35%), Gaps = 55/474 (11%) Query: 30 KFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWR 89 K + EW + FA+ P+ + G V++A EAA+ AF Sbjct: 28 PKGKHLVAGEWLDGAG--TFASA-PAHG-PAHDFAVGTVELVNRACEAAEEAFWTYGYSS 83 Query: 90 RLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWAD 149 R R L +AD +E + + + +TG P + LR FA + Sbjct: 84 RK---ERAAFLRAIADEIEARAEAITEIGSQETGLPEAR-LNGERGRTTGQLRLFADHIE 139 Query: 150 K----------IQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLM--LVWKLAPALCC 197 K + P + + P+G NFPL A AL Sbjct: 140 KGDYLDRRVDAAMPERQPAPRQEIRLVQR-PVGPVAVFGASNFPLAFSTAGGDTAAALAA 198 Query: 198 GNTMVLKPAEQTPLTALYLGSLIKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKI 253 G +V+K P T + + A G PGV +++ G VG A+ HP I + Sbjct: 199 GCPVVVKGHSAHPGTGEIVAEAVDAAIRKTGVHPGVFSLIQGGSRDVGHALVQHPHIKAV 258 Query: 254 AFTGSTEVGKLVK-EAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQG----VFF 308 FTGS G+ + A+R ELG NP + +A L E QG + Sbjct: 259 GFTGSLAGGRALFDLCAARPEPIPFFGELGSVNPMFLLPEA-LKARAETLGQGWAGSLTM 317 Query: 309 NQGQCCTAAS-RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILE 367 GQ CT V +E F +VE K PQ D I + Sbjct: 318 GAGQFCTNPGIAVVIEGADADRFTTAAVEALAK------------VAPQ--TMLTDGIAK 363 Query: 368 LIESGKKEGAKLECGGS--AMEDKGLFIKPTVFSEVTDNMRIAK---EEIFGPVQPILKF 422 G+ A A E G P +F EE+FGP+ +++ Sbjct: 364 AYRDGQARFATRNAVKPLLATESSGRDASPNLFETTGAQFLADHALGEEVFGPLGLVVRV 423 Query: 423 KSIEEVIKRANSTDYGLTAAVFTK--NLDKALKLASALE--SGTVWINCYNALY 472 S E+ + A LTA + +L+ A +L LE +G V +N + Sbjct: 424 GSPAEMEELARGFQGQLTATIHMDAGDLETARRLRPVLERKAGRVLVNGFPTGV 477 >6D97-A nrPDB Length = 547 Score = 222 bits (566), Expect = 3e-58, Method: Composition-based stats. Identities = 100/501 (19%), Positives = 193/501 (38%), Gaps = 53/501 (10%) Query: 7 AVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEG 66 + P + P ++N F+ W S + +P ++ +V E Sbjct: 28 SFATVSPQEVSGSSPAEVQN--------FVQGSWTASANWNWI--VDPLNGDKFIKVAEV 77 Query: 67 DKPDVDKAVEAAQVAFQRGSPWRRLDALSR----GRLLHQLADLVERDR--ATLAALETM 120 ++ +E+ + G L A R G + + A ++ + A L Sbjct: 78 QGTEIKSFMESLSKCPKHGLH-NPLKAPERYLMYGDISAKAAHMLGQPTVLDFFAKLIQR 136 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFT---RHEPIGVCGAI 177 + K + A +++ + L F G + ++ N + P G I Sbjct: 137 VSPKSYQQA-LAEVQVSQKFLENFCGDQVRFLARSFAVPGNHLGQRSNGYRWPYGPVAII 195 Query: 178 TPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFG 237 TP+NFPL + + +L AL GN VLK + + + L+ + G P ++ + G Sbjct: 196 TPFNFPLEIPLLQLMGALYMGNKPVLKVDSKVSIVMEQMIRLLHDCGLPAEDMDFINSDG 255 Query: 238 PTVGAAISS-HPQINKIAFTGSTEVGKLVKEAASRSNLK-RVTLELGGKNPCIVCADA-D 294 + + +P++ FTGS+ V + + ++LK RV LE G + I+ D + Sbjct: 256 AVMNKLLLEANPKMTL--FTGSSRVAEKLA-----ADLKGRVKLEDAGFDWKILGPDVQE 308 Query: 295 LDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSE-FVRRSVEYAKKRPVGDPFDVKTEQ 353 +D Q + GQ C+A S +F+ + S + + + +++R + Sbjct: 309 VDYVAWVCDQDAYACSGQKCSAQSVLFMHKNWSSSGLLEKMKKLSERRKL-----EDLTI 363 Query: 354 GPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGL-----FIKPT-VFSEVTD---- 403 GP + I + K G+K+ GG + + + +KPT VF + + Sbjct: 364 GPVLTVTTEAMIEHMNNLLKIRGSKVLFGGEPLANHSIPKIYGAMKPTAVFVPLEEILKS 423 Query: 404 -NMRIAKEEIFGPVQPILKF--KSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALES 460 N + +EIFGP Q + ++ +E V++ + LTAA+ + + + + Sbjct: 424 GNFELVTKEIFGPFQVVTEYSEDQLELVLEACERMNAHLTAAIVSNDPLFLQDVLGRSVN 483 Query: 461 GTVWINC---YNALYAQAPFG 478 GT + FG Sbjct: 484 GTTYAGIRARTTGAPQNHWFG 504 >5DBV-A nrPDB Length = 445 Score = 222 bits (565), Expect = 4e-58, Method: Composition-based stats. Identities = 97/462 (20%), Positives = 172/462 (37%), Gaps = 64/462 (13%) Query: 69 PDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTG----- 123 D+++A+EAA+ A +++ R +++ + TLA + +TG Sbjct: 16 DDMNQAIEAAKEAQLVV---KKMSMDQREKIISAIRKKTIEHAETLARMAVEETGMGNVG 72 Query: 124 -KPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNF 182 K H + + A D+ + P GV GAITP Sbjct: 73 HKILKHQLVAEKTPGTEDITTTAWSGDR-----------GLTLVEMGPFGVIGAITPCTN 121 Query: 183 PLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPP-GVVNIVPGFGP--- 238 P ++ L GNT+V P T+ + LI EA G VNI Sbjct: 122 PSETIICNTIGMLAGGNTVVFNPHPAAIKTSNFAVQLINEASLSAGGPVNIACSVRKPTL 181 Query: 239 TVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLA 298 + SH I IA TG V V ++ KR G P +V AD+ A Sbjct: 182 DSSKIMMSHQDIPLIAATGGPGVVTAVLQSG-----KRGIGAGAGNPPVLVDETADIRKA 236 Query: 299 VECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQID 358 E G F+ A V + + +E + V+ + I Sbjct: 237 AEDIINGCTFDNNLPAIAEKEVVAIDAIANELMNYMVKE--------------QGCYAIT 282 Query: 359 QKQFDKILELIESGK-------KEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEE 411 ++Q +K+ L+ + K + A+ G ++ I+ +F + EE Sbjct: 283 KEQQEKLTNLVITPKGLNRNCVGKDARTLLGMIGIDVPSN-IRCIIFEG-EKEHPLISEE 340 Query: 412 IFGPVQPILKFKSIEEVIKRANSTDYG--LTAAVFTKNLDKALKLASALESGTVWINCYN 469 + P+ I++ KS ++ +++A ++G +A + +KN+D+ A A+++ + N + Sbjct: 341 LMMPILGIVRAKSFDDAVEKAVWLEHGNRHSAHIHSKNVDRITTYAKAIDTAILVKNAPS 400 Query: 470 ALYAQAPFGGFK------MSGNGRELGEYALAEYTEVKTVTI 505 YA FGG S G G + + +T+ + + Sbjct: 401 --YAAIGFGGEGFCTFTIASRTGE--GLTSASTFTKRRRCVM 438 >1EZ0-A nrPDB Length = 510 Score = 200 bits (509), Expect = 1e-51, Method: Composition-based stats. Identities = 93/464 (20%), Positives = 161/464 (34%), Gaps = 56/464 (12%) Query: 42 ESKSGKKFATCNPSTREQI-CEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLL 100 ++ F N T E + + +V+ +AA A + +RRL+ R LL Sbjct: 2 NPQTDNVFYATNAFTGEALPLAFPVHTEVEVN---QAATAAAKVARDFRRLNNSKRASLL 58 Query: 101 HQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAG------WADKIQGK 154 +A +E + A ++T P + ++ LR FA + I Sbjct: 59 RTIASELEARSDDIIARAHLETALPEVR-LTGEIARTANQLRLFADVVNSGSYHQAILDT 117 Query: 155 TIPTDDNVVCFTRHE---PIGVCGAITPWNFPLLMLV--WKLAPALCCGNTMVLKPAEQT 209 PT + +G NFPL A AL G +++K Sbjct: 118 PNPTRAPLPKPDIRRQQIALGPVAVFGASNFPLAFSAAGGDTASALAAGCPVIVKGHTAH 177 Query: 210 PLTALYLGSLIKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLV 265 P T+ + I++A P + ++ G +G A+ SHP+I + FTGS G+ + Sbjct: 178 PGTSQIVAECIEQALKQEQLPQAIFTLLQGNQRALGQALVSHPEIKAVGFTGSVGGGRAL 237 Query: 266 KEAAS-RSNLKRVTLELGGKNPCIVCAD-----ADLDLAVECAHQGVFFNQGQCCTAASR 319 A R ELG NP + ADL + + GQ CT Sbjct: 238 FNLAHERPEPIPFYGELGAINPTFIFPSAMRAKADL---ADQFVASMTMGCGQFCTKPGV 294 Query: 320 VFV----EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKE 375 VF E Q + E + + + P + Q + + D I + Sbjct: 295 VFALNTPETQAFIETAQSLIRQQSPSTLLTPGIRDSYQSQVVSRGSDDGIDVTFSQAESP 354 Query: 376 GAKLECGGSAMEDKGLFIKPTVFSEVTDN---MRIAKEEIFGPVQPILKFKSIEEVIKRA 432 + +F ++N +EEIFGP I+ +++ +++ + Sbjct: 355 ----------------CVASALFVTSSENWRKHPAWEEEIFGPQSLIVVCENVADMLSLS 398 Query: 433 NSTDYGLTAAVFTK--NLDKALKLASALE--SGTVWINCYNALY 472 LTA + + + +L LE +G + N + Sbjct: 399 EMLAGSLTATIHATEEDYPQVSQLIPRLEEIAGRLVFNGWPTGV 442 >5JFN-A nrPDB Length = 524 Score = 198 bits (505), Expect = 3e-51, Method: Composition-based stats. Identities = 80/414 (19%), Positives = 152/414 (36%), Gaps = 56/414 (13%) Query: 92 DALSRGRLLHQLADLVERDR--ATLAALETMDTG------KPFLHAFFIDLEGCIRTLRY 143 R R + + D++ ++ + +TG K + + I L Sbjct: 112 SMSDRARFVQGIRDVILNQDTLEKMSRMAVEETGMGNYEHKLIKNRLAGEKTPGIEDLTT 171 Query: 144 FAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVL 203 A + DN + + P GV GAITP P +V L GN++V Sbjct: 172 DA-----------FSGDNGLTLVEYSPFGVIGAITPTTNPTETIVCNSIGMLAAGNSVVF 220 Query: 204 KPAEQTPLTALYLGSLIKEA----GFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGST 259 P + +L L LI + G P +V V A+ +HP++ + TG Sbjct: 221 SPHPRARQVSLLLVRLINQKLAALGAPENLVVTVEKPSIENTNAMMAHPKVRMLVATGGP 280 Query: 260 EVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASR 319 + K V S K+ G P +V A+++ A G F+ A Sbjct: 281 AIVKAVL-----STGKKAIGAGAGNPPVVVDETANIEKAACDIVNGCSFDNNLPXVAEKE 335 Query: 320 VFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQI-DQKQFDKILELIESGKKEGAK 378 + Q+ + F++K +I D ++ +L+ + K G + Sbjct: 336 IIAVAQIADYLI---------------FNLKKNGAYEIKDPAVLQQLQDLVLTAKG-GPQ 379 Query: 379 LECGGSA----MEDKGLFIKP---TVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKR 431 +C G + + G+ + + EV +EE+ P+ P+++ +++++ I Sbjct: 380 TKCVGKSAVWLLSQIGISVDASIKIILMEVPREHPFVQEELMMPILPLVRVETVDDAIDL 439 Query: 432 ANSTDYG--LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMS 483 A ++ TA + + ++ K K+A +++ N + A GG S Sbjct: 440 AIEVEHDNRHTAIMHSTDVRKLTKMAKLIQTTIFVKNGPSYAGLGA--GGEGYS 491 >5UJU-A nrPDB Length = 576 Score = 169 bits (429), Expect = 2e-42, Method: Composition-based stats. Identities = 99/478 (20%), Positives = 165/478 (34%), Gaps = 58/478 (12%) Query: 43 SKSGKKFATCNPSTREQIC--EVEEGDKPDVDKAVEAAQVAF-----QRGSPWRRLDALS 95 S GK F P++ E + G D+ ++ A WR + Sbjct: 60 SHLGKTFELDQPASGETVGAERSPYGVALDIRYP-KSTPDALIAAAAAAQRTWREAGPSA 118 Query: 96 RGRLLHQLADLVERDRATLAA----------LETMDTGKPFLHAFFID-LEGCIRTLRYF 144 + ++ + R +A + G P ++ + LR Sbjct: 119 WIGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDQLRRI 178 Query: 145 AGWA--DKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMV 202 A +K QGK P G+ FP L L GNT++ Sbjct: 179 PADAHWEKPQGKNPPLAMQKRYTIVPRGTGLVLGC--CTFPTWNGYPGLFADLATGNTVI 236 Query: 203 LKPAEQTPL----TALYLGSLIKEAGFPPGVVNIV---PGFGPTVGAAISSHPQINKIAF 255 +KP L T +++EAGF P VV ++ P G V ++ P+I I F Sbjct: 237 VKPHPGAILPLAITVRIARDVLREAGFDPNVVTLLATEPNDGALV-QDLALRPEIKLIDF 295 Query: 256 TGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCT 315 TGST+ G ++ A ++ +V E G N ++ + DL A + + GQ CT Sbjct: 296 TGSTQNGTWLERHAHQA---QVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSGQMCT 352 Query: 316 AASRVFVEE---------QVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKIL 366 A ++V + E + +K GDP G Q D + Sbjct: 353 APQNIYVPRDGIRTADGHASFDEVAQAIAGAVQKLT-GDPARSVELIGAI----QNDGVT 407 Query: 367 ELIESGKKEGAKLE----CGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKF 422 I++ + G L A D + + +V D + +E FGP+ ++ Sbjct: 408 ARIDAARAVGRVLLDSQTLQHPAFPDARVRTPLVLQLDVADREK-FTQEWFGPISFVIAT 466 Query: 423 KSIEEVIKRANS--TDYG-LTAAVFTKNLDKALKLASALESGTV--WINCYNALYAQA 475 S + + A ++G LT +V++ D A G V IN ++ Sbjct: 467 DSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGVFVNQ 524 >3MY7-A nrPDB Length = 452 Score = 168 bits (426), Expect = 5e-42, Method: Composition-based stats. Identities = 76/435 (17%), Positives = 148/435 (34%), Gaps = 42/435 (9%) Query: 63 VEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALS--RGRLLHQLADLVERDRATLAALETM 120 + + ++D + + A + + + + R L + LA Sbjct: 1 MPVTNMAELDAMIARVKKAQEEFATYSQEQVDKIFRAASLAANQARI-----PLAQQAVE 55 Query: 121 DTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPW 180 ++G + I + + + D+ + DDN+ T EP+G+ I P Sbjct: 56 ESGMGIVEDKVIKNHFASEFI--YNKYKDEQTCGILEEDDNLGTMTIAEPVGIICGIVPT 113 Query: 181 NFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA----GFPPGVVNIVPGF 236 P ++K +L N ++ P + + L+ +A G P ++ + Sbjct: 114 TNPTSTAIFKSLISLKTRNGIIFSPHPRAKNSTNDAAKLVLDAAVAAGAPKDIIGWIDQP 173 Query: 237 GPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLD 296 + A+ H I I TG A+ S+ K G P ++ AD+ Sbjct: 174 SVELSNALMKHDDIALILATGGPG-----MVKAAYSSGKPAIGVGAGNVPVVIDETADIK 228 Query: 297 LAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQ 356 AV F+ G C + V V ++VY E R K + K + Sbjct: 229 RAVASVLMSKTFDNGVVCASEQAVIVVDEVYDEVKERF-ASHKAHVLSKTDADKVRKVLL 287 Query: 357 IDQKQFDKILELIESGKKE--GAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFG 414 ID KI+ + E G K+ + +G +V+ + A E++ Sbjct: 288 IDGALNAKIVGQPATAIAEMAGVKVPADTKVLIGEG-------LGKVSYDDAFAHEKL-S 339 Query: 415 PVQPILKFKSIEEVIKRANSTD----YGLTAAVFTK---NLDKALKLASALESGTVWINC 467 P + + + E+ + +A + G T+ ++T N D+ +++ + IN Sbjct: 340 PTLGMFRADNFEDAVAQAVTMVEIGGIGHTSGLYTNQDVNADRIRYFGDKMKTARILINI 399 Query: 468 YNALYAQAPFGGFKM 482 GG Sbjct: 400 PTT------HGGIGD 408 >5J7I-A nrPDB Length = 488 Score = 146 bits (370), Expect = 2e-35, Method: Composition-based stats. Identities = 71/441 (16%), Positives = 149/441 (33%), Gaps = 46/441 (10%) Query: 58 EQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAAL 117 + +++ +V +E A+ A + ++ +++ +A+ + LAA+ Sbjct: 23 SMLRDIDLQSIQEVRNYLEEAKAAQKILE---KMTQSEIDKIVESMANAAREEAGRLAAM 79 Query: 118 ETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAI 177 +TG + + + + I D+ + +P+G+ I Sbjct: 80 AVEETGFGNVEDKTLKNLFAANDVYNSIKDVKTVG--IIRRDEENRVWEIAQPVGIVAGI 137 Query: 178 TPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKE----AGFPPGVVNIV 233 P P +++K A+ N +V P +++E AG P G+++ + Sbjct: 138 IPSTNPTSTVIFKALIAVKARNAIVFSPHPSAAKCTAEAARIMQEAAERAGAPKGLISCI 197 Query: 234 PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA 293 + H + I TG + K A+ S+ K G P + A Sbjct: 198 TQPTMAATNELMKHKLTDVILATGGPGLVK-----AAYSSGKPAYGVGPGNVPVYIHESA 252 Query: 294 DLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQ 353 ++ AV+ Q F+ G C + + V+E + + V + + Sbjct: 253 NIAKAVQLIIQSKTFDYGTICASEQALLVDESIKEKVVAELKQ---------------QG 297 Query: 354 GPQIDQKQFDKILELIESGKKEGAKLECGGSAM--EDKGLFIKPTVFSEVTDNMRIAKEE 411 +++++ K+ +I AK+ + E G+ I V V + + KE Sbjct: 298 AYFLNEEEKQKVASIIMVNGSLNAKIVGKAPQVIAEMAGIEIPSDVKLLVAEETEVGKEY 357 Query: 412 IF-----GPVQPILKFKSIEEVIKRANST----DYGLTAAVFTKNLDKALKLASALESGT 462 F P+ K +EE + A G T + ++ +G Sbjct: 358 PFSIEKLSPILAFYIVKGMEEASELAQKLLEVGGLGHTVGIHAEDEKVIEAYTIDKPAGR 417 Query: 463 VWINCYNALYAQAPFGGFKMS 483 + +N FGG + Sbjct: 418 IVVNAGTT------FGGIGAT 432 >3K9D-A nrPDB Length = 464 Score = 139 bits (350), Expect = 4e-33, Method: Composition-based stats. Identities = 70/434 (16%), Positives = 132/434 (30%), Gaps = 49/434 (11%) Query: 67 DKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPF 126 +V +E+A A + + + ++ +AD R LA + +TG Sbjct: 10 SIQEVRNLIESANKAQKELAAMSQQQID---TIVKAIADAGYGAREKLAKMAHEETGFGI 66 Query: 127 LHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLM 186 I + + + I + D+ P+GV + P P Sbjct: 67 WQDKVIKNVFASKHVYNYIKDMKTIG--MLKEDNEKKVMEVAVPLGVVAGLIPSTNPTST 124 Query: 187 LVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKE----AGFPPGVVNIVPGFGPTVGA 242 +++K ++ GN++V P L +I E AG P G ++ + Sbjct: 125 VIYKTLISIKAGNSIVFSPHPNALKAILETVRIISEAAEKAGCPKGAISCMTVPTIQGTD 184 Query: 243 AISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECA 302 + H I TG + A+ S+ G P + A++ AV+ Sbjct: 185 QLMKHKDTAVILATGGSA-----MVKAAYSSGTPAIGVGPGNGPAFIERSANIPRAVKHI 239 Query: 303 HQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEY-------AKKRPVGD-PFDVKTEQG 354 F+ G C + V VE + + A+ +G Sbjct: 240 LDSKTFDNGTICASEQSVVVERVNKEAVIAEFRKQGAHFLSDAEAVQLGKFILRPNGSMN 299 Query: 355 PQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRI-AKEEIF 413 P I K I L G + + + E +I E Sbjct: 300 PAIVGKSVQHIANL------AGLTVPADARVL----------IAEETKVGAKIPYSREKL 343 Query: 414 GPVQPILKFKSIEEVIKRANSTDY----GLTAAVFTKNLDKALKLASALESGTVWINCYN 469 P+ ++ +E + + Y G T + +++ + + A + +N Sbjct: 344 APILAFYTAETWQEACELSMDILYHEGAGHTLIIHSEDKEIIREFALKKPVSRLLVNTPG 403 Query: 470 ALYAQAPFGGFKMS 483 AL GG + Sbjct: 404 AL------GGIGAT 411 >1O20-A nrPDB Length = 427 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 87/467 (18%), Positives = 149/467 (31%), Gaps = 91/467 (19%) Query: 71 VDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKP----F 126 +D+ +E A+ + R + + + ++A+ ++ R + +D K Sbjct: 13 MDELLEKAKKVREAWDVLRNATTREKNKAIKKIAEKLDERRKEILEANRIDVEKARERGV 72 Query: 127 LHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTR---------HEPIGVCGAI 177 + L + + + + G P + + + R PIG G I Sbjct: 73 KESLVDRLALNDKRIDEMIKACETVIGLKDPVGEVIDSWVREDGLRIARVRVPIGPIGII 132 Query: 178 ---TPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA----GFPPGVV 230 P + V AL GNT++L+ + + S I+EA P V Sbjct: 133 YESRP-----NVTVETTILALKSGNTILLRGGSDALNSNKAIVSAIREALKETEIPESSV 187 Query: 231 NIV-PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELG-GKNPCI 288 + V I ++ + G + R N LE G G Sbjct: 188 EFIENTDRSLVLEMIRLREYLSLV-----IPRGGYGLISFVRDNATVPVLETGVGNCHIF 242 Query: 289 VCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFD 348 V ADL AV G C AA ++ V E++ EF+ Sbjct: 243 VDESADLKKAVPVIINAKTQRPG-TCNAAEKLLVHEKIAKEFL----------------- 284 Query: 349 VKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIA 408 P I +E +K G ++ +K I P V D+ Sbjct: 285 ------PVI-----------VEELRKHGVEV-----RGCEKTREIVPDVVPATEDDWP-- 320 Query: 409 KEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCY 468 E + I K+++E I+ G + ++ T+N A K S +++ V++N Sbjct: 321 -TEYLDLIIAIKVVKNVDEAIEHIKKYSTGHSESILTENYSNAKKFVSEIDAAAVYVNAS 379 Query: 469 NALYAQAPFGGFKMSGNGREL----------GEYALAEYTEVKTVTI 505 F G G E+ G L E T K V + Sbjct: 380 TRFTDGGQF------GFGAEIGISTQRFHARGPVGLRELTTYKFVVL 420 >4GHK-A nrPDB Length = 444 Score = 99.5 bits (247), Expect = 3e-21, Method: Composition-based stats. Identities = 84/440 (19%), Positives = 131/440 (29%), Gaps = 78/440 (17%) Query: 98 RLLHQLADLVERDRATLAALETMDTG----KPFLHAFFIDLEGCIRTLRYFAGWADKIQG 153 L +A +ERD L A D K AF L + L+ ++ Sbjct: 52 AALEAVARAIERDAGALKAANARDVARAKDKGLDAAFVDRLTLSDKALKTMVEGLRQVAT 111 Query: 154 KTIPT---------DDNVVCFTRHEPIGVCGAI---TPWNFPLLMLVWKLAPALCCGNTM 201 P + P+GV G I P + + A L GN Sbjct: 112 LPDPIGEMSNLKYRPSGIQVGQMRVPLGVIGIIYESRP-----NVTIDAAALCLKSGNAT 166 Query: 202 VLKPAEQTPLTALYLGSLI----KEAGFPPGVVNIV-PGFGPTVGAAISSHPQINKIAFT 256 +L+ + + L LI EAG P V +V VG I+ ++ I Sbjct: 167 ILRGGSEALESNTALAKLIGEGLAEAGLPQDTVQVVETADRAAVGRLITMTEYVDVIV-- 224 Query: 257 GSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTA 316 GK + E + L G V A + A+ G C Sbjct: 225 --PRGGKSLIERLINEARVPMIKHLDGICHVYVDDRASVTKALTVCDNAKTHRYG-TCNT 281 Query: 317 ASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEG 376 + V + + +++ V D Sbjct: 282 METLLVARGIAPAVLSPLGRLYREKGVELRVDADAR------------------------ 317 Query: 377 AKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTD 436 A LE G + P + TD + E PV I I+ I+ N + Sbjct: 318 AVLEAAG---------VGP--LVDATDED--WRTEYLAPVLAIKIVDGIDAAIEHIN--E 362 Query: 437 YG--LTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFG-----GFKMSGNGREL 489 YG T A+ T++ D+A++ ++S +V +N FG G Sbjct: 363 YGSHHTDAIVTEDHDRAMRFLREVDSASVMVNASTRFADGFEFGLGAEIGISNDKLHAR- 421 Query: 490 GEYALAEYTEVKTVTIKLGD 509 G L T +K V + G+ Sbjct: 422 GPVGLEGLTSLKYVVLGHGE 441 >1VLU-A nrPDB Length = 468 Score = 82.6 bits (203), Expect = 4e-16, Method: Composition-based stats. Identities = 75/448 (16%), Positives = 142/448 (31%), Gaps = 85/448 (18%) Query: 76 EAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAAL------ETMDTG------ 123 + A+ A + G+ + + R +L+++ D ++ + + +TG Sbjct: 18 QIAKNARKAGNILKTISNEGRSDILYKIHDALKANAHAIEEANKIDLAVAKETGLADSLL 77 Query: 124 KPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTI--PTDDNVVCFTRHEPIGVCGAITPWN 181 K E ++ ++ A D + + DD + + P+GV I + Sbjct: 78 KRLDLFKGDKFEVMLQGIKDVAELEDPVGKVKMARELDDGLTLYQVTAPVGVLLVI--FE 135 Query: 182 FPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIK--------EAGFPPGVVNIV 233 ++ A ++ GN +LK +++ T + ++ E G P G V ++ Sbjct: 136 SRPEVIANITALSIKSGNAAILKGGKESVNTFREMAKIVNDTIAQFQSETGVPVGSVQLI 195 Query: 234 PGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADA 293 V + I+ + GS + + +K+ + V G + DA Sbjct: 196 E-TRQDVSDLLDQDEYIDLVVPRGSNALVRKIKD----TTKIPVLGHADGICSIYLDEDA 250 Query: 294 DLDLAVECAHQGVFFN-QGQCCTAASRVFVEE--QVYSEFVRRS-------VEYAKKRPV 343 DL A + G C A + + + E + + K Sbjct: 251 DLIKAKRISLDAKTNYPAG--CNAMETLLINPKFSKWWEVLENLTLEGGVTIHATKDLKT 308 Query: 344 GDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTD 403 FD E G + Q + + + Sbjct: 309 AY-FDKLNELGKLTEAIQCKTV----------------------------------DADE 333 Query: 404 NMRIAKEEIFGPVQPILKF-KSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGT 462 KE F + KF S E I+ N+ T A+ T+N A K ++S Sbjct: 334 EQDFDKE--FLSLDLAAKFVTSTESAIQHINTHSSRHTDAIVTENKANAEKFMKGVDSSG 391 Query: 463 VWINCYNALYAQAPFGGFKMSGNGRELG 490 V+ N GF+ G G E+G Sbjct: 392 VYWNASTRFAD-----GFRY-GFGAEVG 413 >4JBE-A nrPDB Length = 445 Score = 77.2 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 81/448 (18%), Positives = 133/448 (29%), Gaps = 87/448 (19%) Query: 64 EEGDKPDVDKAVEA-AQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDT 122 +V KAVE A+ A + L +AD + R + A D Sbjct: 30 SNAMTNEVAKAVEECARAAKSAAPSLSGAPDTAIDAALESMADRLLAHRDAVLAANAEDI 89 Query: 123 GK--------------PFLHAFFIDLEGCIRTLRYFAGWA-DKIQGKTIPTDDNVVCFTR 167 K + D+ LR AG + + D + R Sbjct: 90 AKAEAGGMSAGLLDRLTITESRLTDM---ADQLRLLAGAPHPQRTVELSTLDGGLRLVER 146 Query: 168 HEPIGVCGAITPWNF---PLLMLVWKLAPALC-CGNTMVLKPAEQTPLTALYLGSL---- 219 P+GV GA N+ P + + +A L N VL+ +A L + Sbjct: 147 RRPVGVIGA----NYEARPNVTV--DVASQLVKSRNAGVLRTGSAALKSAQRLLEVVIRP 200 Query: 220 -IKEAGFPPGVVNIVPGFGPTVGAAISSHPQ-INKIAFTGSTEVGKLVKEAASRSNLKRV 277 + ++G VV +VP A+ P + + GS E + + A++ ++ + Sbjct: 201 ALTDSGIDANVVQLVPRPEREAAGALVRLPDLVPLVILRGSGESTRALALEAAQHGVRTL 260 Query: 278 TLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEY 337 GG V AD D V G C + + + + VY EF E Sbjct: 261 AHADGGGV-LYVDEKADRD-TVRSLVVNSLDRLG-VCNRLNLLLIHDAVYEEFWPVVSEA 317 Query: 338 AKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTV 397 +R V P ++ L+ A++ Sbjct: 318 LAERGV------SPSLPPYDHPIGYEWALDSEREATVTVARV------------------ 353 Query: 398 FSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASA 457 V + +RIA EE GL A + T++ A + Sbjct: 354 -DGVAEAVRIANEET------------------------SGLAAGIATEDARAAEEFFDG 388 Query: 458 LESGTVWINCYNALYAQAPFGGFKMSGN 485 + V+ N L G +G Sbjct: 389 YQGTGVFWNAPTRLLDGFKLLGVPETGI 416 >2H5G-A nrPDB Length = 463 Score = 73.0 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 77/460 (16%), Positives = 127/460 (27%), Gaps = 101/460 (21%) Query: 81 AFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFF--------- 131 A G L+ R ++H LADL+ R + K A Sbjct: 38 ARSGGRMLATLEPEQRAEIIHHLADLLTDQRDEILLA----NKKDLEEAEGRLAAPLLKR 93 Query: 132 -----IDLEGCIRTLRYFAGWADKIQGKTI---PTDDNVVCFTRHEPIGVCGAITPWNF- 182 L LR A + G+ + N+ PIGV I F Sbjct: 94 LSLSTSKLNSLAIGLRQIAASSQDSVGRVLRRTRIAKNLELEQVTVPIGVLLVI----FE 149 Query: 183 --PLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEA----GFPPGVVNIVPGF 236 P + A A+ GN ++LK ++ + L L +EA G V +V Sbjct: 150 SRPDCLP-QVAALAIASGNGLLLKGGKEAAHSNRILHLLTQEALSIHGV-KEAVQLVN-T 206 Query: 237 GPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLD 296 V I+ I GS+++ + +++AA V G V ++A +D Sbjct: 207 REEVEDLCRLDKMIDLIIPRGSSQLVRDIQKAAKG---IPVMGHSEGICHMYVDSEASVD 263 Query: 297 LAVECAHQGVFFNQGQCCTAASRVFVEEQ-----VYSEFVRRSVEYAKKRPVGDPFDVKT 351 C A + + ++ + + K G F Sbjct: 264 KVTRLVRDSKCEYPA-ACNALETLLIHRDLLRTPLFDQIIDMLRVEQVKIHAGPKFASYL 322 Query: 352 EQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEE 411 P ++S + E LE Sbjct: 323 TFSP-----------SEVKSLRTEYGDLE------------------------------- 340 Query: 412 IFGPVQPILKFKSIEEVIKRANSTDYG--LTAAVFTKNLDKALKLASALESGTVWINCYN 469 I ++++ I YG T + T++ + A ++S V+ N Sbjct: 341 -----LCIEVVDNVQDAIDHI--HKYGSSHTDVIVTEDENTAEFFLQHVDSACVFWNAST 393 Query: 470 ALYAQAPFG-----GFKMSGNGRELGEYALAEYTEVKTVT 504 FG G S G L K + Sbjct: 394 RFSDGYRFGLGAEVGISTSRIHAR-GPVGLEGLLTTKWLL 432 >4Q1V-A nrPDB Length = 710 Score = 33.3 bits (75), Expect = 0.27, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 21/57 (36%), Gaps = 4/57 (7%) Query: 445 TKNLDKALKLASALESGTVWINCYNALYAQAPFGGFK---MSGNGRELGEYALAEYT 498 TK + L SG +N N +Q PF K SG G Y + Y+ Sbjct: 367 TKRKEVIFTAVEGLRSGHFAVNVSNGKISQ-PFENCKESEHSGTLSASGTYLIDRYS 422 >4U83-A nrPDB Length = 382 Score = 32.5 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 31/96 (32%), Gaps = 12/96 (12%) Query: 71 VDKAVEAAQVAFQRGSPWRR------LDALSRGRLLHQLADLVER----DRATLAALETM 120 +AV A+ AF+ + R + + +LAD+ R + L A Sbjct: 252 AAQAVGMARAAFEAARDYARERITFGKPIIEHQAVAFRLADMATRIETARQMVLHAAALR 311 Query: 121 DTGKP-FLHAFFIDLEGCIRTLRYFAGWADKIQGKT 155 + GKP A L A +I G Sbjct: 312 EAGKPCLTEASMAKLVAS-EMAEQVCSAAIQIHGGY 346 >4XFE-A nrPDB Length = 341 Score = 32.5 bits (73), Expect = 0.50, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 24/71 (33%), Gaps = 9/71 (12%) Query: 120 MDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITP 179 + GK A D+ T + FAG + + I +G+ G + P Sbjct: 44 QNMGKKLEQASNGDI-----TFKMFAGGVLGSEKEVIEQAQIGAVQMTRVSLGIVGPVVP 98 Query: 180 ----WNFPLLM 186 +N P + Sbjct: 99 DVNVFNMPFVF 109 >3AGK-A nrPDB Length = 373 Score = 32.1 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 34/101 (33%), Gaps = 23/101 (22%) Query: 328 SEFVRRSVEYAKKRPVGD-PFDVKTEQGP----QIDQKQFDKILELIESGKKEGAKLECG 382 EF + G+ + E G I + + + E +E K GA++ Sbjct: 287 EEFKLHLAKGTGMIVYGEKDVEAALEMGAVKTLLIHE-SREDLEEWVEKAKSSGAQVIVV 345 Query: 383 GSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFK 423 ++ + F+K FG + IL+F+ Sbjct: 346 PESLAEAEWFLK-----------------TFGGLAGILRFR 369 >6AHD-9 nrPDB Length = 800 Score = 31.7 bits (71), Expect = 0.73, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 26/78 (33%), Gaps = 14/78 (17%) Query: 54 PSTREQICEVEEGDKPDVDKAVEAAQV------------AFQRGSPWRRLDAL--SRGRL 99 P T + I + + ++ + + AA+ PW A R R Sbjct: 150 PVTADVINPMALRQREELREKLAAAKEKRLLNQKLGKIKTLGEDDPWLDDTAAWIERSRQ 209 Query: 100 LHQLADLVERDRATLAAL 117 L + DL E+ L + Sbjct: 210 LQKEKDLAEKRAKLLEEM 227 >3Q09-A nrPDB Length = 248 Score = 31.4 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 5/31 (16%), Positives = 13/31 (41%) Query: 82 FQRGSPWRRLDALSRGRLLHQLADLVERDRA 112 F+ W ++ R ++ L+E+ + Sbjct: 27 FKLRPDWNKVPVAERKGAAEEVKKLIEKHKD 57 >4G9Q-A nrPDB Length = 269 Score = 31.0 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 10/72 (13%) Query: 84 RGSPWRRLDALSRGRLLHQLADLV---ERDRATLAALETMDTG-KPFLHAFFIDLEGCIR 139 G W+R R R L +A L+ E T A + ++ G KP ++ I Sbjct: 62 YGDVWQRPGLNRRDRSLVTIAALIARGEAPALTYYADQALENGVKP------SEISETIT 115 Query: 140 TLRYFAGWADKI 151 L Y++GW + Sbjct: 116 HLAYYSGWGKAM 127 >4N4Q-A nrPDB Length = 296 Score = 31.0 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 31/83 (37%), Gaps = 23/83 (27%) Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVG-- 262 PA TP T + +AG VVN + +++ I TGST Sbjct: 12 PAMVTPFTKDG---KLHKAGV-KEVVNF-----------LVEKQKVDGIYITGSTGEFLL 56 Query: 263 ------KLVKEAASRSNLKRVTL 279 K V + + +N RVTL Sbjct: 57 LSFEDKKEVMKLVAEANAGRVTL 79 >5Z0Q-C nrPDB Length = 389 Score = 31.0 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 13/76 (17%) Query: 43 SKSGKKFATC-NPSTREQICEVEEGDKPDVD-KAVEAAQVAFQRGSPWRRLDALSRGRLL 100 + G A NP R + + +G PDVD A AA A++ G PW L Sbjct: 245 AGLGASLAVIPNPELRARFNRMRKGMVPDVDVLAYVAASAAWREGQPW-----------L 293 Query: 101 HQLADLVERDRATLAA 116 D + +R LA Sbjct: 294 DAQLDYLRANRDMLAQ 309 >3HOA-A nrPDB Length = 509 Score = 30.6 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 26/86 (30%), Gaps = 2/86 (2%) Query: 68 KPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRAT--LAALETMDTGKP 125 + A A A+ + + + R R + LA L+ + + G P Sbjct: 15 RETAYLASLGALAAWDQRTMIPKKGHEHRARQMAALARLLHQRMTDPRIGEWLEKVEGSP 74 Query: 126 FLHAFFIDLEGCIRTLRYFAGWADKI 151 + D +R R A I Sbjct: 75 LVQDPLSDAAVNVREWRQAYERARAI 100 >3DOD-A nrPDB Length = 448 Score = 29.8 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 9/22 (40%), Positives = 13/22 (59%) Query: 96 RGRLLHQLADLVERDRATLAAL 117 R + L +LA L+E +AAL Sbjct: 193 RDQCLRELAQLLEEHHEEIAAL 214 >3LOO-A nrPDB Length = 365 Score = 29.8 bits (66), Expect = 3.1, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 8/49 (16%) Query: 410 EEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASAL 458 EEIF P +L F + E I A +YG T++L + K +AL Sbjct: 226 EEIF-PYVDVL-FGNETEAIALAKEFNYG------TEDLREIGKRIAAL 266 >4WJB-A nrPDB Length = 424 Score = 29.4 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 30/71 (42%), Gaps = 1/71 (1%) Query: 215 YLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNL 274 + AG GV + G T GA + ++ +I + G+ VG AA ++ Sbjct: 145 RFAPAMVSAGVFSGVYTLEYGLSRTDGAGRTIGEELERIGYAGAEPVGGYPVHAAYELHI 204 Query: 275 KR-VTLELGGK 284 ++ LE GK Sbjct: 205 EQGAILERAGK 215 >3UF0-A nrPDB Length = 273 Score = 29.4 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 28/79 (35%), Gaps = 13/79 (16%) Query: 227 PGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLEL---GG 283 G +V G G +G AI+ G G V +K V E+ GG Sbjct: 30 AGRTAVVTGAGSGIGRAIAH----------GYARAGAHVLAWGRTDGVKEVADEIADGGG 79 Query: 284 KNPCIVCADADLDLAVECA 302 +V ADL+ A A Sbjct: 80 SAEAVVADLADLEGAANVA 98 >3HSK-A nrPDB Length = 381 Score = 29.4 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 7/57 (12%), Positives = 16/57 (28%) Query: 322 VEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 V + FV + P ++ + D + ++ +G K Sbjct: 105 VAGDIEKSFVEAGLAVVSNAKNYRREKDVPLVVPIVNPEHIDVVENKVKQAVSKGGK 161 >1J3N-A nrPDB Length = 408 Score = 29.4 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 39/105 (37%), Gaps = 13/105 (12%) Query: 205 PAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPT--VGA---------AISSHPQINKI 253 P + AL + +K+AG P V + G + VG H + + Sbjct: 270 PHPEGKGAALAMARALKDAGIAPEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMV 329 Query: 254 AFTGSTEVGKLVKEAASRSNLKRV-TLELGGKNPCIVCADADLDL 297 + T S +G L+ A + + V L G P I D D +L Sbjct: 330 SSTKSM-IGHLLGAAGAVEAIATVQALYHGVIPPTINLEDPDPEL 373 >2WMI-B nrPDB Length = 606 Score = 29.0 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 20/35 (57%) Query: 19 ALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCN 53 A P P ++ ++ TK+FI+ ++ +GK F N Sbjct: 342 AHPAPSKSKVLEDTKVFIHGDYSNKGNGKFFVNVN 376 >2IPH-A nrPDB Length = 181 Score = 29.0 bits (64), Expect = 5.3, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 390 GLFIKPTVFSEVTDNMRIAKEEIFG-PVQPI 419 G ++ PTVF T + + +E FG P+ I Sbjct: 17 GFWVSPTVFITTTHVIPTSAKEFFGEPLTSI 47 >4WHB-E nrPDB Length = 461 Score = 28.7 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 324 EQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGG 383 E Y E + + + A + V FD P + + + I +G +GA++ G Sbjct: 88 EGRYVEVIEEAAQLALRNGVTTVFDTHNAIEPVLAAR------DRINAGISQGARIFAAG 141 Query: 384 SAMEDKGLF 392 + + G F Sbjct: 142 TIVGMGGPF 150 >3ZQJ-A nrPDB Length = 993 Score = 28.7 bits (63), Expect = 6.1, Method: Composition-based stats. Identities = 8/20 (40%), Positives = 12/20 (60%) Query: 82 FQRGSPWRRLDALSRGRLLH 101 F +PWR+L A +R +L Sbjct: 358 FDVDTPWRKLPAKARKAILE 377 >1R6V-A nrPDB Length = 671 Score = 28.7 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 17/37 (45%) Query: 460 SGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAE 496 +G +W + A +GG+ S +E +YA+ Sbjct: 251 AGIIWATDHGAKVMNHSWGGWGYSYTMKEAFDYAMEH 287 >1O54-A nrPDB Length = 277 Score = 28.7 bits (63), Expect = 6.9, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 8 VENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQ 59 + G ++ AL + + +I+ W K G +FAT P+T + Sbjct: 173 ISEGFDEKDVDALFLDVPDPW-----NYIDKCWEALKGGGRFATVCPTTNQV 219 >2MBB-A nrPDB Length = 106 Score = 28.3 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 22/67 (32%) Query: 5 NGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVE 64 NG G+ + + + ++ EW + K F S +C + Sbjct: 8 NGKTLKGETTTEAVDAATAEKVFKQYANDNGVDGEWTYDDATKTFTVTEGSNEFPLCSLP 67 Query: 65 EGDKPDV 71 EG +V Sbjct: 68 EGVDQEV 74 >1V9N-A nrPDB Length = 360 Score = 28.3 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 39/96 (40%), Gaps = 20/96 (20%) Query: 399 SEVTDNMRIAKEEIFGP----------VQPILKFKSIEEVIKRANSTDYGLTAAVFTKNL 448 + +R+ +E GP + ++ ++S++ IK+A T G+ V +N Sbjct: 72 VNLHPKIRVIRE---GPSYALIDGDEGLGQVVGYRSMKLAIKKAKDTGIGI---VIARNS 125 Query: 449 DK----ALKLASALESGTVWINCYNALYAQAPFGGF 480 + A E G + I+ N+ AP GG Sbjct: 126 NHYGIAGYYALMAAEEGMIGISMTNSRPLVAPTGGI 161 >5E7H-A nrPDB Length = 260 Score = 28.3 bits (62), Expect = 8.5, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 14/34 (41%), Gaps = 1/34 (2%) Query: 398 FSEVTDNMRIAKEEIF-GPVQPILKFKSIEEVIK 430 ++ +E+F GPV I ++ + + Sbjct: 157 IDDLKLQFECFVKEVFTGPVFQIAMCENFDAALN 190 >4YJI-A nrPDB Length = 495 Score = 28.3 bits (62), Expect = 8.8, Method: Composition-based stats. Identities = 23/100 (23%), Positives = 30/100 (30%), Gaps = 14/100 (14%) Query: 5 NGAVENGQPDRKPPALPRPIRNLEVKFTK--IFINNEWHESKSGKKFATCNPSTREQICE 62 NG + P P+RN T+ IN E + G + Sbjct: 386 NGVFDRFDLLLAPTLACMPVRNATDGCTEGPSQINGEEIDPLIGWCMTYLTNFSGHPSAS 445 Query: 63 VEEG------------DKPDVDKAVEAAQVAFQRGSPWRR 90 V G D V AA AF+R SPW + Sbjct: 446 VPAGLIDGLPAGMLIIGDRQADLDVIAASAAFERASPWSQ 485 >5E7G-A nrPDB Length = 456 Score = 28.3 bits (62), Expect = 9.1, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 14/34 (41%), Gaps = 1/34 (2%) Query: 398 FSEVTDNMRIAKEEIF-GPVQPILKFKSIEEVIK 430 ++ +E+F GPV I ++ + + Sbjct: 353 IDDLKLQFECFVKEVFTGPVFQIAMCENFDAALN 386 >3C3E-A nrPDB Length = 311 Score = 28.3 bits (62), Expect = 9.3, Method: Composition-based stats. Identities = 9/45 (20%), Positives = 18/45 (40%), Gaps = 2/45 (4%) Query: 323 EEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILE 367 E + + + E + +G P + T GP I ++L+ Sbjct: 170 EASISPKVLEAF-EKEENILIG-PSNPITSIGPIISLPGMRELLK 212 >3UPY-A nrPDB Length = 445 Score = 28.3 bits (62), Expect = 9.4, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 26/92 (28%), Gaps = 6/92 (6%) Query: 319 RVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAK 378 R+ V EF+ S + + + + + + L + EG Sbjct: 218 RLLV------EFIDGSKTMVEMAAIANATGLVPDIAGMHGPRASIDQLSHTLIPQAEGGV 271 Query: 379 LECGGSAMEDKGLFIKPTVFSEVTDNMRIAKE 410 L G G + P VF + E Sbjct: 272 LSKSGVVDYSIGKGVSPGVFVVAKMDHPRLNE 303 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.156 0.456 Lambda K H 0.267 0.0479 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,424,967 Number of Sequences: 36641 Number of extensions: 1040851 Number of successful extensions: 4214 Number of sequences better than 10.0: 146 Number of HSP's better than 10.0 without gapping: 224 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 3044 Number of HSP's gapped (non-prelim): 288 length of query: 512 length of database: 10,336,785 effective HSP length: 101 effective length of query: 411 effective length of database: 6,636,044 effective search space: 2727414084 effective search space used: 2727414084 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 62 (28.3 bits)