BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P47863 (323 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3IYZ-A nrPDB 614 e-176 2ZZ9-A nrPDB 609 e-175 3GD8-A nrPDB 439 e-124 1YMG-A nrPDB 239 1e-63 3M9I-A nrPDB 233 1e-61 4OJ2-X nrPDB 231 2e-61 4NEF-A nrPDB 230 6e-61 3D9S-A nrPDB 229 1e-60 1J4N-A nrPDB 223 1e-58 1IH5-A nrPDB 222 1e-58 3CLL-A nrPDB 159 2e-39 5I32-A nrPDB 152 2e-37 2EVU-A nrPDB 107 1e-23 3NE2-A nrPDB 103 9e-23 2W1P-A nrPDB 100 9e-22 2O9F-A nrPDB 88 4e-18 3LLQ-A nrPDB 83 1e-16 3C02-A nrPDB 62 4e-10 6F7H-A nrPDB 59 2e-09 1LDI-A nrPDB 55 3e-08 5W4T-C nrPDB 31 0.81 2DO0-A nrPDB 29 3.5 3KZO-A nrPDB 27 9.4 >3IYZ-A nrPDB Length = 340 Score = 614 bits (1583), Expect = e-176, Method: Compositional matrix adjust. Identities = 305/308 (99%), Positives = 305/308 (99%), Gaps = 1/308 (0%) Query: 16 PCSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISL 75 P SR SIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISL Sbjct: 34 PSSR-SIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISL 92 Query: 76 CFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL 135 CFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL Sbjct: 93 CFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL 152 Query: 136 VTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGF 195 VTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCD KRTDVTGSVALAIGF Sbjct: 153 VTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVALAIGF 212 Query: 196 SVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPD 255 SVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPD Sbjct: 213 SVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPD 272 Query: 256 VELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDS 315 VELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDS Sbjct: 273 VELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDS 332 Query: 316 SGEVLSSV 323 SGEVLSSV Sbjct: 333 SGEVLSSV 340 >2ZZ9-A nrPDB Length = 301 Score = 609 bits (1571), Expect = e-175, Method: Compositional matrix adjust. Identities = 300/301 (99%), Positives = 300/301 (99%) Query: 23 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIA 82 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIA Sbjct: 1 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIA 60 Query: 83 TMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVV 142 TMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVV Sbjct: 61 TMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVV 120 Query: 143 GGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHL 202 GGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCD KRTDVTGSVALAIGFSVAIGHL Sbjct: 121 GGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVALAIGFSVAIGHL 180 Query: 203 FAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRL 262 FAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRL Sbjct: 181 FAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRL 240 Query: 263 KEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSS 322 KEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSS Sbjct: 241 KEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSS 300 Query: 323 V 323 V Sbjct: 301 V 301 >3GD8-A nrPDB Length = 223 Score = 439 bits (1129), Expect = e-124, Method: Compositional matrix adjust. Identities = 216/223 (96%), Positives = 219/223 (98%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHI 91 QAFWKAVTAEFLAMLIFVLLS+GSTINWGG+E PLPVDMVLISLCFGLSIATMVQCFGHI Sbjct: 1 QAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHI 60 Query: 92 SGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVH 151 SGGHINPAVTVAMVCTRKISIAKSVFYI AQCLGAIIGAGILYLVTPPSVVGGLGVT VH Sbjct: 61 SGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVH 120 Query: 152 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGAS 211 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGS+ALAIGFSVAIGHLFAINYTGAS Sbjct: 121 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGAS 180 Query: 212 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCP 254 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAG LYEYVFCP Sbjct: 181 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 223 >1YMG-A nrPDB Length = 263 Score = 239 bits (610), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 117/265 (44%), Positives = 172/265 (64%), Gaps = 11/265 (4%) Query: 31 TQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGH 90 + +FW+A+ AEF A L +V +G+++ W P P+ ++ ++L FGL++AT+VQ GH Sbjct: 6 SASFWRAICAEFFASLFYVFFGLGASLRWA----PGPLHVLQVALAFGLALATLVQAVGH 61 Query: 91 ISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTV 150 ISG H+NPAVT A + ++S+ +++ Y+ AQ LGA+ GA +LY VTPP+V G L + T+ Sbjct: 62 ISGAHVNPAVTFAFLVGSQMSLLRAICYMVAQLLGAVAGAAVLYSVTPPAVRGNLALNTL 121 Query: 151 HGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGA 210 H ++ G +VE+ +T Q V IFA+ D +R GSVALA+GFS+ +GHLF + YTGA Sbjct: 122 HPGVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYYTGA 181 Query: 211 SMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAA 270 MNPARSF PA++ N+ NHW+YWVGP+IGA L LY+++ P RLK S+ Sbjct: 182 GMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFP------RLKSV-SERL 234 Query: 271 QQTKGSYMEVEDNRSQVETEDLILK 295 KGS + + +V E + LK Sbjct: 235 SILKGSRPSESNGQPEVTGEPVELK 259 >3M9I-A nrPDB Length = 220 Score = 233 bits (593), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 106/223 (47%), Positives = 155/223 (69%), Gaps = 4/223 (1%) Query: 33 AFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHIS 92 +FW+A+ AEF A L +V +G+++ W P P+ ++ ++L FGL++AT+VQ GHIS Sbjct: 2 SFWRAIFAEFFATLFYVFFGLGASLRWA----PGPLHVLQVALAFGLALATLVQAVGHIS 57 Query: 93 GGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHG 152 G H+NPAVT A + ++S+ +++ Y+ AQ LGA+ GA +LY VTPP+V G L + T+H Sbjct: 58 GAHVNPAVTFAFLVGSQMSLLRAICYVVAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHP 117 Query: 153 NLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGASM 212 ++ G +VE+ +T Q V IFA+ D +R GSVALA+GFS+ +GHLF + YTGA M Sbjct: 118 GVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYYTGAGM 177 Query: 213 NPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPD 255 NPARSF PA++ N+ NHW+YWVGP+IGA L LY+++ P Sbjct: 178 NPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFPR 220 >4OJ2-X nrPDB Length = 274 Score = 231 bits (590), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 116/231 (50%), Positives = 156/231 (67%), Gaps = 5/231 (2%) Query: 33 AFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHIS 92 AF +AV AEFLA L+FV +GS +NW LP ++ I++ FGL I T+VQ GHIS Sbjct: 11 AFSRAVFAEFLATLLFVFFGLGSALNW---PQALP-SVLQIAMAFGLGIGTLVQALGHIS 66 Query: 93 GGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHG 152 G HINPAVTVA + +S+ ++ FY+ AQ LGA+ GA +L+ +TP + G L V + Sbjct: 67 GAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSN 126 Query: 153 NLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGASM 212 + TAG + VEL +T QLV IFAS D +R + G+ AL+IGFSVA+GHL I+YTG SM Sbjct: 127 STTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSM 186 Query: 213 NPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYV-FCPDVELKRRL 262 NPARS PAV+ G +++HW++W+GP++GA+L LY YV F P L RL Sbjct: 187 NPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERL 237 >4NEF-A nrPDB Length = 242 Score = 230 bits (587), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 116/231 (50%), Positives = 156/231 (67%), Gaps = 5/231 (2%) Query: 33 AFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHIS 92 AF +AV AEFLA L+FV +GS +NW LP ++ I++ FGL I T+VQ GHIS Sbjct: 8 AFSRAVFAEFLATLLFVFFGLGSALNW---PQALP-SVLQIAMAFGLGIGTLVQALGHIS 63 Query: 93 GGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHG 152 G HINPAVTVA + +S+ ++ FY+ AQ LGA+ GA +L+ +TP + G L V + Sbjct: 64 GAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSN 123 Query: 153 NLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGASM 212 + TAG + VEL +T QLV IFAS D +R + G+ AL+IGFSVA+GHL I+YTG SM Sbjct: 124 STTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSM 183 Query: 213 NPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYV-FCPDVELKRRL 262 NPARS PAV+ G +++HW++W+GP++GA+L LY YV F P L RL Sbjct: 184 NPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERL 234 >3D9S-A nrPDB Length = 266 Score = 229 bits (584), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 130/266 (48%), Positives = 170/266 (63%), Gaps = 12/266 (4%) Query: 27 KGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQ 86 K V + AF KAV AEFLA LIFV +GS + W + LP ++ I+L FGL+I T+ Q Sbjct: 4 KEVCSVAFLKAVFAEFLATLIFVFFGLGSALKW---PSALP-TILQIALAFGLAIGTLAQ 59 Query: 87 CFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLG 146 G +SGGHINPA+T+A++ +IS+ ++ FY+ AQ +GAI GAGILY V P + G L Sbjct: 60 ALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLA 119 Query: 147 VTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAIN 206 V ++ N T G ++VELI+TFQL IFAS DS+RT GS AL+IG SV +GHL I Sbjct: 120 VNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIY 179 Query: 207 YTGASMNPARSFGPAVIMGNWE-NHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEA 265 +TG SMNPARSFGPAV+M + HW++WVGPI+GAVLA LY Y+ P+ + Sbjct: 180 FTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPN-------SLS 232 Query: 266 FSKAAQQTKGSYMEVEDNRSQVETED 291 S+ KG+Y ED Q E Sbjct: 233 LSERVAIIKGTYEPDEDWEEQREERK 258 >1J4N-A nrPDB Length = 271 Score = 223 bits (567), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 117/268 (43%), Positives = 172/268 (64%), Gaps = 15/268 (5%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPV--------DMVLISLCFGLSIAT 83 + FW+AV AEFLAM++F+ +S+GS + G P+ D V +SL FGLSIAT Sbjct: 8 KLFWRAVVAEFLAMILFIFISIGSAL---GFHYPIKSNQTTGAVQDNVKVSLAFGLSIAT 64 Query: 84 MVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVG 143 + Q GHISG H+NPAVT+ ++ + +IS+ +++ YI AQC+GAI+ IL +T Sbjct: 65 LAQSVGHISGAHLNPAVTLGLLLSCQISVLRAIMYIIAQCVGAIVATAILSGITSSLPDN 124 Query: 144 GLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLF 203 LG+ + + +G GL +E+I T QLV + A+ D +R D+ GS LAIGFSVA+GHL Sbjct: 125 SLGLNALAPGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSGPLAIGFSVALGHLL 184 Query: 204 AINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCP-DVELKRRL 262 AI+YTG +NPARSFG +VI N+++HWI+WVGP IGA LA +Y+++ P +L R+ Sbjct: 185 AIDYTGCGINPARSFGSSVITHNFQDHWIFWVGPFIGAALAVLIYDFILAPRSSDLTDRV 244 Query: 263 KEAFSKAAQQTKGSYMEVEDNRSQVETE 290 K S ++ ++ +D S+VE + Sbjct: 245 KVWTSGQVEEYD---LDADDINSRVEMK 269 >1IH5-A nrPDB Length = 269 Score = 222 bits (566), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 117/263 (44%), Positives = 166/263 (63%), Gaps = 7/263 (2%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINWG---GSENPLPVDMVLISLCFGLSIATMVQCF 88 + FW+AV AEFLA +FV +S+GS + + G+ D V +SL FGLSIAT+ Q Sbjct: 8 KLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSV 67 Query: 89 GHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVT 148 GHISG H+NPAVT+ ++ + +ISI +++ YI AQC+GAI+ IL +T LG Sbjct: 68 GHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRN 127 Query: 149 TVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYT 208 + + +G GL +E+I T QLV + A+ D +R D+ GS LAIG SVA+GHL AI+YT Sbjct: 128 DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYT 187 Query: 209 GASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCP-DVELKRRLKEAFS 267 G +NPARSFG AVI N+ NHWI+WVGP IG LA +Y+++ P +L R+K S Sbjct: 188 GCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTS 247 Query: 268 KAAQQTKGSYMEVEDNRSQVETE 290 ++ ++ +D S+VE + Sbjct: 248 GQVEEYD---LDADDINSRVEMK 267 >3CLL-A nrPDB Length = 300 Score = 159 bits (401), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 105/265 (39%), Positives = 154/265 (58%), Gaps = 20/265 (7%) Query: 1 MSDGAAARRWGK--CGPPCSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTIN 58 +S+ A A + GK PP + + K +W+ FW+A AEF+A L+F+ ++V + I Sbjct: 24 VSEEAQAHQHGKDYVDPPPAPFFDLGELK-LWS--FWRAAIAEFIATLLFLYITVATVI- 79 Query: 59 WGGSENPL---PVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKS 115 G S+ + V ++ I+ FG I +V C ISGGHINPAVT + RK+ + ++ Sbjct: 80 -GHSKETVVCGSVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVELLRA 138 Query: 116 VFYITAQCLGAIIGAGIL--YLVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFT 173 + Y+ AQCLGAI G G++ ++ P + GG G +V G L E+I TF LV+T Sbjct: 139 LVYMIAQCLGAICGVGLVKAFMKGPYNQFGG-GANSVALGYNKGTALGAEIIGTFVLVYT 197 Query: 174 IFASCDSKRTDVTGSV----ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGN--- 226 +F++ D KR+ V L IGF+V + HL I TG +NPARSFG AVI + Sbjct: 198 VFSATDPKRSARDSHVPILAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNSNKV 257 Query: 227 WENHWIYWVGPIIGAVLAGALYEYV 251 W++ WI+WVGP IGA +A A ++YV Sbjct: 258 WDDQWIFWVGPFIGAAVAAAYHQYV 282 >5I32-A nrPDB Length = 275 Score = 152 bits (383), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 96/239 (40%), Positives = 138/239 (57%), Gaps = 11/239 (4%) Query: 25 AFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVD---MVLISLCFGLSI 81 +F ++ A +A AEF++ L+FV VGS I + + +D +V I++C G ++ Sbjct: 33 SFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFAL 92 Query: 82 ATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV 141 V +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT Sbjct: 93 FVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVT---- 148 Query: 142 VGGLGVTT--VHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVA-LAIGFSVA 198 GGL V T V L + G+++E+IITF LV+T++A+ + G++A LAIG V Sbjct: 149 -GGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVG 207 Query: 199 IGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVE 257 L A ++G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF E Sbjct: 208 ANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSE 266 >2EVU-A nrPDB Length = 246 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 86/240 (35%), Positives = 118/240 (49%), Gaps = 26/240 (10%) Query: 36 KAVTAEFLAMLIFVLLSVGSTI------NWGGSENPL---------PVDMVLISLCFGLS 80 K AEF+ I V GS + G S NP D V I L FG + Sbjct: 6 KRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLAFGFA 65 Query: 81 IATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVT--P 138 IA + G+ISG HINPAVT+ + +K + V YI AQ LGA G+ I Sbjct: 66 IAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQCAGIG 125 Query: 139 PSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVA 198 + VGGLG T ++ +L E++ TF L+ TI +R G + IG +VA Sbjct: 126 AATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDERAP-KGFAGIIIGLTVA 184 Query: 199 IGHLFAI-NYTGASMNPARSFGP----AVIMGN--WENHWIYWVGPIIGAVLAGALYEYV 251 G + + N +G+S+NPAR+FGP + G W + IY +GPI+GAVLA Y+Y+ Sbjct: 185 -GIITTLGNISGSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTYQYL 243 >3NE2-A nrPDB Length = 246 Score = 103 bits (257), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 78/192 (40%), Positives = 107/192 (55%), Gaps = 12/192 (6%) Query: 69 DMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAII 128 D I + F L+IA ++ G ISG HINPAVT+A+ + + V YI AQ +GA + Sbjct: 55 DWFAIGMAFALAIAAVIYSLGRISGAHINPAVTIALWSIGRFPGREVVPYIVAQFIGAAL 114 Query: 129 GAGILYL--VTP-PSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDV 185 G+ +L+L V P + VGGLG T + G +L E I TF L+ I +R Sbjct: 115 GS-LLFLACVGPAAATVGGLGATAPFPGIGYGQAILTEAIGTFLLMLVIMGVAVDERAP- 172 Query: 186 TGSVALAIGFSVAIGHLFAI-NYTGASMNPARSFGPAV---IMG--NWENHWIYWVGPII 239 G L IG +V G + I N TG+S+NPAR+FGP + +MG W+ IY +GPI+ Sbjct: 173 PGFAGLVIGLTVG-GIITTIGNITGSSLNPARTFGPYLGDSLMGINLWQYFPIYVIGPIV 231 Query: 240 GAVLAGALYEYV 251 GAV A LY Y+ Sbjct: 232 GAVAAAWLYNYL 243 >2W1P-A nrPDB Length = 279 Score = 100 bits (249), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 68/191 (35%), Positives = 98/191 (51%), Gaps = 8/191 (4%) Query: 60 GGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYI 119 GGS P +++IS FG + V +SGG++NPAVT+A+V R I + + Sbjct: 78 GGSN---PAQLIMISFGFGFGVMVGVFITYRVSGGNLNPAVTLALVLARAIPPFRGILMA 134 Query: 120 TAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCD 179 Q + + AG +TP + + G + GL +E T L T+ Sbjct: 135 FTQIVAGMAAAGAASAMTPGEIAF---ANALGGGASRTRGLFLEAFGTAILCLTVLMLAV 191 Query: 180 SKRTDVTGSVALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWEN-HWIYWVGPI 238 K T IG ++ I HL I YTGA +NPARSFGPAV ++ N HWIYW+GPI Sbjct: 192 EKH-RATWFAPFVIGIALLIAHLICIYYTGAGLNPARSFGPAVAARSFPNYHWIYWLGPI 250 Query: 239 IGAVLAGALYE 249 +GA LA ++++ Sbjct: 251 LGAFLAYSIWQ 261 >2O9F-A nrPDB Length = 234 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 60/184 (32%), Positives = 90/184 (48%), Gaps = 21/184 (11%) Query: 66 LPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLG 125 L + ++L FGL++ TM GHISGGH NPAVT+ + + + V Y+ AQ +G Sbjct: 35 LGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVG 94 Query: 126 AIIGAGILYLVTPPSVVGGLGV-TTVHGNLTAGHG------------LLVELIITFQLVF 172 I+ A +LYL+ G G G + G+G L+VEL+++ + Sbjct: 95 GIVAAALLYLIAS----GKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLL 150 Query: 173 TIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNW--ENH 230 I + D + G +AIG + + HL +I T S+NPARS A+ G W E Sbjct: 151 VIHGATD--KFAPAGFAPIAIGLACTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQL 208 Query: 231 WIYW 234 W +W Sbjct: 209 WFFW 212 >3LLQ-A nrPDB Length = 256 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 67/214 (31%), Positives = 106/214 (49%), Gaps = 12/214 (5%) Query: 36 KAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGH 95 + + AEF V GS + + + L + ++L FGL++ TM G ISGGH Sbjct: 31 RKLLAEFFGTFWLVFGGCGSAV-FAAAFPELGIGFTGVALAFGLTVLTMAYAVGGISGGH 89 Query: 96 INPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV---VGGLGVTTVHG 152 NPAV+V + + + V Y+ AQ GAI+ A LY++ +GG Sbjct: 90 FNPAVSVGLTVAGRFPASSLVPYVIAQVAGAIVAAAALYVIATGKAGIDLGGFASNGYGE 149 Query: 153 NLTAGH----GLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYT 208 + G+ LL+E+I+T + I S + G +AIG ++ + HL +I T Sbjct: 150 HSPGGYSLVSALLIEIILTAFFLIVILGSTHGRVP--AGFAPIAIGLALTLIHLISIPVT 207 Query: 209 GASMNPARSFGPAVIMGNW--ENHWIYWVGPIIG 240 S+NPARS G A+ +G W + W++W+ PI+G Sbjct: 208 NTSVNPARSTGQALFVGGWALQQLWLFWLAPIVG 241 >3C02-A nrPDB Length = 258 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 62/261 (23%), Positives = 111/261 (42%), Gaps = 33/261 (12%) Query: 29 VWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCF 88 ++ +++ + EFL + + L G+T N+ L D + L +GL++ + Sbjct: 4 LFYKSYVREFIGEFLGTFVLMFLGEGATANF--HTTGLSGDWYKLCLGWGLAVFFGILVS 61 Query: 89 GHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILY-----LVTPPSVVG 143 +SG H+N AV++ + K + K Y AQ LGA +G +Y ++ + Sbjct: 62 AKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQ 121 Query: 144 GLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDS---------KRTDVTGSVALAIG 194 T+ + +++ ELI+T L+ I D K + V G + L IG Sbjct: 122 FAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENICGKFHILKLSSVVGLIILCIG 181 Query: 195 FSVAIGHLFAINYTGASMNPAR----------SFGPAVIMGNWENHWIYWVGPIIGAVLA 244 + F N TG ++NP+R ++G + W+ V P +G+V+ Sbjct: 182 IT------FGGN-TGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVF 234 Query: 245 GALYEYVFCPDVELKRRLKEA 265 Y+ V CP V+L K+ Sbjct: 235 CQFYDKVICPLVDLANNEKDG 255 >6F7H-A nrPDB Length = 301 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/288 (22%), Positives = 115/288 (39%), Gaps = 50/288 (17%) Query: 40 AEFLAMLIFVLLSVGS---TINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHI 96 AEFL + + +LL+ G+ + G ++ + + L L++ + G++SG H+ Sbjct: 26 AEFLGVFVLMLLTQGAVAQAVTSGETKG----NFFTMFLAGSLAVTIAIYVGGNVSGAHL 81 Query: 97 NPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL---------------VTPPSV 141 NPA ++AM ++ K YI Q L A +G Y+ VT P Sbjct: 82 NPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNLTVTGPKE 141 Query: 142 VGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTD--------VTGSVALAI 193 + T L+ +G L +++ T L+ + A D + V G + LA+ Sbjct: 142 TASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILAL 201 Query: 194 GFSVAIGHLFAINYTGASMNPARSFGPAVI--MGNWENH---------WIYWVGPIIGAV 242 G S+ G +NPAR GP + + W W+ V P++GA Sbjct: 202 GLSMGAN-------CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVGAT 254 Query: 243 LAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETE 290 + A Y+ + + + A + Q K S +E + +E + Sbjct: 255 VGTATYQLLVA--LHHPEGPEPAQDLVSAQHKASELETPASAQMLECK 300 >1LDI-A nrPDB Length = 281 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 58/209 (27%), Positives = 87/209 (41%), Gaps = 32/209 (15%) Query: 73 ISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGI 132 IS+ +GL +A + +SG H+NPAVT+A+ K + +I +Q GA A + Sbjct: 44 ISVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAAL 103 Query: 133 LYLV----------TPPSVVGGLGVTTVHGNLTAG--------HGLLVELIITFQLVFTI 174 +Y + T V G + + G + VE++IT L+ I Sbjct: 104 VYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILMGLI 163 Query: 175 FASCDSKRTDVTGSVA-LAIGFSVAIGHLFAINYTGASMNPARSFGPAVI--MGNWEN-- 229 A D G +A L IG +A+ TG +MNPAR FGP V + W N Sbjct: 164 LALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVA 223 Query: 230 ---------HWIYWVGPIIGAVLAGALYE 249 + GPI+GA++ Y Sbjct: 224 FTGGRDIPYFLVPLFGPIVGAIVGAFAYR 252 >5W4T-C nrPDB Length = 327 Score = 30.8 bits (68), Expect = 0.81, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 4/91 (4%) Query: 103 AMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHGNLTAGHGLLV 162 A+ + SVF + A +G +L+ PPS + G +T L Sbjct: 114 AIQIPENTPVGTSVFMVNATDPDQGVGGSVLFSFQPPSQF--FSIDGARGIVTVTRALDY 171 Query: 163 ELIITFQLVFTIFASCDSKRTDVTGSVALAI 193 E I +QL T+ A+ KR ++ LAI Sbjct: 172 ETTIAYQL--TVNATDQDKRRPLSSLANLAI 200 >2DO0-A nrPDB Length = 114 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 28/50 (56%), Gaps = 3/50 (6%) Query: 240 GAVLAGALYEYVFCPDVELK---RRLKEAFSKAAQQTKGSYMEVEDNRSQ 286 GA+ AG L VF +++ K ++LKE FS A + +E +D +S+ Sbjct: 7 GALQAGRLGSTVFVANLDYKVGWKKLKEVFSMAGVVVRADILEDKDGKSR 56 >3KZO-A nrPDB Length = 359 Score = 27.3 bits (59), Expect = 9.4, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 21/50 (42%) Query: 179 DSKRTDVTGSVALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWE 228 D + D G S+ + H Y GA + A+S+G GNWE Sbjct: 235 DERYMDWAAQNVAESGGSLQVSHDIDSAYAGADVVYAKSWGALPFFGNWE 284 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3IYZ-A nrPDB 432 e-121 2ZZ9-A nrPDB 427 e-120 1IH5-A nrPDB 303 7e-83 1J4N-A nrPDB 301 3e-82 1YMG-A nrPDB 298 3e-81 3GD8-A nrPDB 297 5e-81 3D9S-A nrPDB 278 2e-75 4OJ2-X nrPDB 278 2e-75 3M9I-A nrPDB 269 1e-72 4NEF-A nrPDB 264 3e-71 3CLL-A nrPDB 251 4e-67 6F7H-A nrPDB 214 6e-56 5I32-A nrPDB 210 7e-55 3C02-A nrPDB 207 5e-54 2EVU-A nrPDB 203 9e-53 3NE2-A nrPDB 190 8e-49 1LDI-A nrPDB 181 4e-46 2W1P-A nrPDB 181 5e-46 3LLQ-A nrPDB 180 9e-46 2O9F-A nrPDB 174 5e-44 Sequences not found previously or not previously below threshold: 4AGS-A nrPDB 32 0.33 4QGK-A nrPDB 30 1.4 5Z7D-A nrPDB 30 1.9 5YZW-A nrPDB 30 1.9 5XEX-A nrPDB 29 2.3 3SBG-A nrPDB 29 2.9 3E66-A nrPDB 29 2.9 5YJJ-A nrPDB 29 3.4 2OZU-A nrPDB 28 3.8 4Z3P-A nrPDB 28 5.8 4PPM-A nrPDB 28 7.1 CONVERGED! >3IYZ-A nrPDB Length = 340 Score = 432 bits (1110), Expect = e-121, Method: Composition-based stats. Identities = 303/307 (98%), Positives = 303/307 (98%) Query: 17 CSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLC 76 S SIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLC Sbjct: 34 PSSRSIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLC 93 Query: 77 FGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLV 136 FGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLV Sbjct: 94 FGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLV 153 Query: 137 TPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFS 196 TPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCD KRTDVTGSVALAIGFS Sbjct: 154 TPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVALAIGFS 213 Query: 197 VAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDV 256 VAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDV Sbjct: 214 VAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDV 273 Query: 257 ELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSS 316 ELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSS Sbjct: 274 ELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSS 333 Query: 317 GEVLSSV 323 GEVLSSV Sbjct: 334 GEVLSSV 340 >2ZZ9-A nrPDB Length = 301 Score = 427 bits (1098), Expect = e-120, Method: Composition-based stats. Identities = 300/301 (99%), Positives = 300/301 (99%) Query: 23 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIA 82 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIA Sbjct: 1 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIA 60 Query: 83 TMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVV 142 TMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVV Sbjct: 61 TMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVV 120 Query: 143 GGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHL 202 GGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCD KRTDVTGSVALAIGFSVAIGHL Sbjct: 121 GGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDDKRTDVTGSVALAIGFSVAIGHL 180 Query: 203 FAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRL 262 FAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRL Sbjct: 181 FAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRL 240 Query: 263 KEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSS 322 KEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSS Sbjct: 241 KEAFSKAAQQTKGSYMEVEDNRSQVETEDLILKPGVVHVIDIDRGDEKKGKDSSGEVLSS 300 Query: 323 V 323 V Sbjct: 301 V 301 >1IH5-A nrPDB Length = 269 Score = 303 bits (776), Expect = 7e-83, Method: Composition-based stats. Identities = 117/264 (44%), Positives = 166/264 (62%), Gaps = 7/264 (2%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINWG---GSENPLPVDMVLISLCFGLSIATMVQCF 88 + FW+AV AEFLA +FV +S+GS + + G+ D V +SL FGLSIAT+ Q Sbjct: 8 KLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSV 67 Query: 89 GHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVT 148 GHISG H+NPAVT+ ++ + +ISI +++ YI AQC+GAI+ IL +T LG Sbjct: 68 GHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRN 127 Query: 149 TVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYT 208 + + +G GL +E+I T QLV + A+ D +R D+ GS LAIG SVA+GHL AI+YT Sbjct: 128 DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYT 187 Query: 209 GASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCP-DVELKRRLKEAFS 267 G +NPARSFG AVI N+ NHWI+WVGP IG LA +Y+++ P +L R+K S Sbjct: 188 GCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTS 247 Query: 268 KAAQQTKGSYMEVEDNRSQVETED 291 ++ ++ +D S+VE + Sbjct: 248 GQVEEYD---LDADDINSRVEMKP 268 >1J4N-A nrPDB Length = 271 Score = 301 bits (771), Expect = 3e-82, Method: Composition-based stats. Identities = 115/266 (43%), Positives = 170/266 (63%), Gaps = 9/266 (3%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINW-----GGSENPLPVDMVLISLCFGLSIATMVQ 86 + FW+AV AEFLAM++F+ +S+GS + + D V +SL FGLSIAT+ Q Sbjct: 8 KLFWRAVVAEFLAMILFIFISIGSALGFHYPIKSNQTTGAVQDNVKVSLAFGLSIATLAQ 67 Query: 87 CFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLG 146 GHISG H+NPAVT+ ++ + +IS+ +++ YI AQC+GAI+ IL +T LG Sbjct: 68 SVGHISGAHLNPAVTLGLLLSCQISVLRAIMYIIAQCVGAIVATAILSGITSSLPDNSLG 127 Query: 147 VTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAIN 206 + + + +G GL +E+I T QLV + A+ D +R D+ GS LAIGFSVA+GHL AI+ Sbjct: 128 LNALAPGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSGPLAIGFSVALGHLLAID 187 Query: 207 YTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCP-DVELKRRLKEA 265 YTG +NPARSFG +VI N+++HWI+WVGP IGA LA +Y+++ P +L R+K Sbjct: 188 YTGCGINPARSFGSSVITHNFQDHWIFWVGPFIGAALAVLIYDFILAPRSSDLTDRVKVW 247 Query: 266 FSKAAQQTKGSYMEVEDNRSQVETED 291 S ++ ++ +D S+VE + Sbjct: 248 TSGQVEEYD---LDADDINSRVEMKP 270 >1YMG-A nrPDB Length = 263 Score = 298 bits (762), Expect = 3e-81, Method: Composition-based stats. Identities = 114/268 (42%), Positives = 173/268 (64%), Gaps = 11/268 (4%) Query: 28 GVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQC 87 + + +FW+A+ AEF A L +V +G+++ W P P+ ++ ++L FGL++AT+VQ Sbjct: 3 ELRSASFWRAICAEFFASLFYVFFGLGASLRWA----PGPLHVLQVALAFGLALATLVQA 58 Query: 88 FGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGV 147 GHISG H+NPAVT A + ++S+ +++ Y+ AQ LGA+ GA +LY VTPP+V G L + Sbjct: 59 VGHISGAHVNPAVTFAFLVGSQMSLLRAICYMVAQLLGAVAGAAVLYSVTPPAVRGNLAL 118 Query: 148 TTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINY 207 T+H ++ G +VE+ +T Q V IFA+ D +R GSVALA+GFS+ +GHLF + Y Sbjct: 119 NTLHPGVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYY 178 Query: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFS 267 TGA MNPARSF PA++ N+ NHW+YWVGP+IGA L LY+++ P ++ + S Sbjct: 179 TGAGMNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFPRLK-------SVS 231 Query: 268 KAAQQTKGSYMEVEDNRSQVETEDLILK 295 + KGS + + +V E + LK Sbjct: 232 ERLSILKGSRPSESNGQPEVTGEPVELK 259 >3GD8-A nrPDB Length = 223 Score = 297 bits (760), Expect = 5e-81, Method: Composition-based stats. Identities = 216/223 (96%), Positives = 219/223 (98%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHI 91 QAFWKAVTAEFLAMLIFVLLS+GSTINWGG+E PLPVDMVLISLCFGLSIATMVQCFGHI Sbjct: 1 QAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHI 60 Query: 92 SGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVH 151 SGGHINPAVTVAMVCTRKISIAKSVFYI AQCLGAIIGAGILYLVTPPSVVGGLGVT VH Sbjct: 61 SGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVH 120 Query: 152 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGAS 211 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGS+ALAIGFSVAIGHLFAINYTGAS Sbjct: 121 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGAS 180 Query: 212 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCP 254 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAG LYEYVFCP Sbjct: 181 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 223 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 34/107 (31%), Gaps = 7/107 (6%) Query: 157 GHGLLVELIITFQLVFTIFASC------DSKRTDVTGSVALAIGFSVAIGHLFAINYTGA 210 + E + V S + ++L G S+A + +G Sbjct: 4 WKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGG 63 Query: 211 SMNPARSFGPAVIMGNWENHWIYWVGP-IIGAVLAGALYEYVFCPDV 256 +NPA + ++++ +GA++ + V P V Sbjct: 64 HINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSV 110 >3D9S-A nrPDB Length = 266 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 128/266 (48%), Positives = 168/266 (63%), Gaps = 12/266 (4%) Query: 27 KGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQ 86 K V + AF KAV AEFLA LIFV +GS + W + + + I+L FGL+I T+ Q Sbjct: 4 KEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTI----LQIALAFGLAIGTLAQ 59 Query: 87 CFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLG 146 G +SGGHINPA+T+A++ +IS+ ++ FY+ AQ +GAI GAGILY V P + G L Sbjct: 60 ALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLA 119 Query: 147 VTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAIN 206 V ++ N T G ++VELI+TFQL IFAS DS+RT GS AL+IG SV +GHL I Sbjct: 120 VNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIY 179 Query: 207 YTGASMNPARSFGPAVIMGNWEN-HWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEA 265 +TG SMNPARSFGPAV+M + HW++WVGPI+GAVLA LY Y+ P+ + Sbjct: 180 FTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNS-------LS 232 Query: 266 FSKAAQQTKGSYMEVEDNRSQVETED 291 S+ KG+Y ED Q E Sbjct: 233 LSERVAIIKGTYEPDEDWEEQREERK 258 >4OJ2-X nrPDB Length = 274 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 116/266 (43%), Positives = 165/266 (62%), Gaps = 11/266 (4%) Query: 28 GVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQC 87 + + AF +AV AEFLA L+FV +GS +NW LP ++ I++ FGL I T+VQ Sbjct: 6 ELRSIAFSRAVFAEFLATLLFVFFGLGSALNW---PQALP-SVLQIAMAFGLGIGTLVQA 61 Query: 88 FGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGV 147 GHISG HINPAVTVA + +S+ ++ FY+ AQ LGA+ GA +L+ +TP + G L V Sbjct: 62 LGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAV 121 Query: 148 TTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINY 207 + + TAG + VEL +T QLV IFAS D +R + G+ AL+IGFSVA+GHL I+Y Sbjct: 122 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHY 181 Query: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFS 267 TG SMNPARS PAV+ G +++HW++W+GP++GA+L LY YV P ++ S Sbjct: 182 TGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFP-------PAKSLS 234 Query: 268 KAAQQTKGSYMEVEDNRSQVETEDLI 293 + KG + + +V + Sbjct: 235 ERLAVLKGLEPDTDWEEREVRRRQAV 260 >3M9I-A nrPDB Length = 220 Score = 269 bits (687), Expect = 1e-72, Method: Composition-based stats. Identities = 106/224 (47%), Positives = 155/224 (69%), Gaps = 4/224 (1%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHI 91 +FW+A+ AEF A L +V +G+++ W P P+ ++ ++L FGL++AT+VQ GHI Sbjct: 1 ASFWRAIFAEFFATLFYVFFGLGASLRWA----PGPLHVLQVALAFGLALATLVQAVGHI 56 Query: 92 SGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVH 151 SG H+NPAVT A + ++S+ +++ Y+ AQ LGA+ GA +LY VTPP+V G L + T+H Sbjct: 57 SGAHVNPAVTFAFLVGSQMSLLRAICYVVAQLLGAVAGAAVLYSVTPPAVRGNLALNTLH 116 Query: 152 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGAS 211 ++ G +VE+ +T Q V IFA+ D +R GSVALA+GFS+ +GHLF + YTGA Sbjct: 117 PGVSVGQATIVEIFLTLQFVLCIFATYDERRNGRLGSVALAVGFSLTLGHLFGMYYTGAG 176 Query: 212 MNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPD 255 MNPARSF PA++ N+ NHW+YWVGP+IGA L LY+++ P Sbjct: 177 MNPARSFAPAILTRNFTNHWVYWVGPVIGAGLGSLLYDFLLFPR 220 Score = 36.9 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 43/108 (39%), Gaps = 7/108 (6%) Query: 154 LTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGS--VALAIGFSVAIGHLFAINYTGAS 211 + + E T VF + VALA G ++A + +GA Sbjct: 1 ASFWRAIFAEFFATLFYVFFGLGASLRWAPGPLHVLQVALAFGLALATLVQAVGHISGAH 60 Query: 212 MNPARSFGPAVIMGNWENHW---IYWVGPIIGAVLAGALYEYVFCPDV 256 +NPA +F A ++G+ + Y V ++GAV A+ V P V Sbjct: 61 VNPAVTF--AFLVGSQMSLLRAICYVVAQLLGAVAGAAVLYSVTPPAV 106 >4NEF-A nrPDB Length = 242 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 115/251 (45%), Positives = 160/251 (63%), Gaps = 11/251 (4%) Query: 28 GVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQC 87 + + AF +AV AEFLA L+FV +GS +NW LP ++ I++ FGL I T+VQ Sbjct: 3 ELRSIAFSRAVFAEFLATLLFVFFGLGSALNW---PQALP-SVLQIAMAFGLGIGTLVQA 58 Query: 88 FGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGV 147 GHISG HINPAVTVA + +S+ ++ FY+ AQ LGA+ GA +L+ +TP + G L V Sbjct: 59 LGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAV 118 Query: 148 TTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINY 207 + + TAG + VEL +T QLV IFAS D +R + G+ AL+IGFSVA+GHL I+Y Sbjct: 119 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHY 178 Query: 208 TGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFS 267 TG SMNPARS PAV+ G +++HW++W+GP++GA+L LY YV P ++ S Sbjct: 179 TGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFP-------PAKSLS 231 Query: 268 KAAQQTKGSYM 278 + KG Sbjct: 232 ERLAVLKGLEP 242 >3CLL-A nrPDB Length = 300 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 102/264 (38%), Positives = 150/264 (56%), Gaps = 16/264 (6%) Query: 1 MSDGAAARRWGK--CGPPCSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTIN 58 +S+ A A + GK PP + + K +W+ FW+A AEF+A L+F+ ++V + I Sbjct: 24 VSEEAQAHQHGKDYVDPPPAPFFDLGELK-LWS--FWRAAIAEFIATLLFLYITVATVIG 80 Query: 59 -WGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVF 117 + V ++ I+ FG I +V C ISGGHINPAVT + RK+ + +++ Sbjct: 81 HSKETVVCGSVGLLGIAWAFGGMIFVLVYCTAGISGGHINPAVTFGLFLARKVELLRALV 140 Query: 118 YITAQCLGAIIGAGIL--YLVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIF 175 Y+ AQCLGAI G G++ ++ P + GG G +V G L E+I TF LV+T+F Sbjct: 141 YMIAQCLGAICGVGLVKAFMKGPYNQFGG-GANSVALGYNKGTALGAEIIGTFVLVYTVF 199 Query: 176 ASCDSKRTDVTGS----VALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGN---WE 228 ++ D KR+ L IGF+V + HL I TG +NPARSFG AVI + W+ Sbjct: 200 SATDPKRSARDSHVPILAPLPIGFAVFMVHLATIPITGTGINPARSFGAAVIFNSNKVWD 259 Query: 229 NHWIYWVGPIIGAVLAGALYEYVF 252 + WI+WVGP IGA +A A ++YV Sbjct: 260 DQWIFWVGPFIGAAVAAAYHQYVL 283 >6F7H-A nrPDB Length = 301 Score = 214 bits (544), Expect = 6e-56, Method: Composition-based stats. Identities = 63/300 (21%), Positives = 113/300 (37%), Gaps = 32/300 (10%) Query: 18 SRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCF 77 + IM + + AEFL + + +LL+ G + + + + L Sbjct: 6 APAEIMGHLR--IRSLLARQCLAEFLGVFVLMLLTQG-AVAQAVTSGETKGNFFTMFLAG 62 Query: 78 GLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL-- 135 L++ + G++SG H+NPA ++AM ++ K YI Q L A +G Y+ Sbjct: 63 SLAVTIAIYVGGNVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLY 122 Query: 136 -------------VTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKR 182 VT P + T L+ +G L +++ T L+ + A D + Sbjct: 123 HDALQNYTGGNLTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRN 182 Query: 183 TD-VTGSVALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIM--GNWENH--------- 230 G + +G + L G +NPAR GP + W Sbjct: 183 KGVPAGLEPVVVGMLILALGLSMGANCGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWW 242 Query: 231 WIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETE 290 W+ V P++GA + A Y+ + + + A + Q K S +E + +E + Sbjct: 243 WVPVVAPLVGATVGTATYQLLVA--LHHPEGPEPAQDLVSAQHKASELETPASAQMLECK 300 >5I32-A nrPDB Length = 275 Score = 210 bits (534), Expect = 7e-55, Method: Composition-based stats. Identities = 90/240 (37%), Positives = 133/240 (55%), Gaps = 7/240 (2%) Query: 23 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVD---MVLISLCFGL 79 +F ++ A +A AEF++ L+FV VGS I + + +D +V I++C G Sbjct: 31 FGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGF 90 Query: 80 SIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPP 139 ++ V +ISGGH+NPAVT + +I++ VFY AQ LG+ +L VT Sbjct: 91 ALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGG 150 Query: 140 SVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGS-VALAIGFSVA 198 + +V L + G+++E+IITF LV+T++A+ + G+ LAIG V Sbjct: 151 LA---VPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVG 207 Query: 199 IGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVEL 258 L A ++G SMNPARSFGPAV G++ HW+YWVGP+IG LAG +Y VF E Sbjct: 208 ANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSEH 267 >3C02-A nrPDB Length = 258 Score = 207 bits (527), Expect = 5e-54, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 108/264 (40%), Gaps = 33/264 (12%) Query: 29 VWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCF 88 ++ +++ + EFL + + L G+T N+ L D + L +GL++ + Sbjct: 4 LFYKSYVREFIGEFLGTFVLMFLGEGATANF--HTTGLSGDWYKLCLGWGLAVFFGILVS 61 Query: 89 GHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL-----VTPPSVVG 143 +SG H+N AV++ + K + K Y AQ LGA +G +Y ++ + Sbjct: 62 AKLSGAHLNLAVSIGLSSINKFDLKKIPVYFFAQLLGAFVGTSTVYGLYHGFISNSKIPQ 121 Query: 144 GLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDS---------KRTDVTGSVALAIG 194 T+ + +++ ELI+T L+ I D K + V G + L IG Sbjct: 122 FAWETSRNPSISLTGAFFNELILTGILLLVILVVVDENICGKFHILKLSSVVGLIILCIG 181 Query: 195 FSVAIGHLFAINYTGASMNPARS----------FGPAVIMGNWENHWIYWVGPIIGAVLA 244 + TG ++NP+R +G + W+ V P +G+V+ Sbjct: 182 ITFGGN-------TGFALNPSRDLGSRFLSLIAYGKDTFTKDNFYFWVPLVAPCVGSVVF 234 Query: 245 GALYEYVFCPDVELKRRLKEAFSK 268 Y+ V CP V+L K+ Sbjct: 235 CQFYDKVICPLVDLANNEKDGVDL 258 >2EVU-A nrPDB Length = 246 Score = 203 bits (516), Expect = 9e-53, Method: Composition-based stats. Identities = 85/243 (34%), Positives = 116/243 (47%), Gaps = 24/243 (9%) Query: 32 QAFWKAVTAEFLAMLIFVLLSVGSTI------NWGGSENPL---------PVDMVLISLC 76 + K AEF+ I V GS + G S NP D V I L Sbjct: 2 VSLTKRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLA 61 Query: 77 FGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLV 136 FG +IA + G+ISG HINPAVT+ + +K + V YI AQ LGA G+ I Sbjct: 62 FGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQC 121 Query: 137 T--PPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIG 194 + VGGLG T ++ +L E++ TF L+ TI +R G + IG Sbjct: 122 AGIGAATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDER-APKGFAGIIIG 180 Query: 195 FSVAIGHLFAINYTGASMNPARSFGP----AVIMGN--WENHWIYWVGPIIGAVLAGALY 248 +VA N +G+S+NPAR+FGP + G W + IY +GPI+GAVLA Y Sbjct: 181 LTVAGIITTLGNISGSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTY 240 Query: 249 EYV 251 +Y+ Sbjct: 241 QYL 243 Score = 47.7 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 48/111 (43%), Gaps = 12/111 (10%) Query: 33 AFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHIS 92 ++W+A+ AE + + ++ +G ++ P I + GL++A ++ G+IS Sbjct: 142 SYWQAMLAEVVGTFLLMITIMGIAVD-----ERAPKGFAGIII--GLTVAGIITTLGNIS 194 Query: 93 GGHINPAVTVA-----MVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTP 138 G +NPA T M+ Y+ +GA++ A +T Sbjct: 195 GSSLNPARTFGPYLNDMIFAGTDLWNYYSIYVIGPIVGAVLAALTYQYLTS 245 >3NE2-A nrPDB Length = 246 Score = 190 bits (482), Expect = 8e-49, Method: Composition-based stats. Identities = 81/243 (33%), Positives = 111/243 (45%), Gaps = 23/243 (9%) Query: 31 TQAFWKAVTAEFLAMLIFVLLSVGSTI---------------NWGGSENPLPVDMVLISL 75 T K TAE + I V G+ + N G D I + Sbjct: 2 TMTLAKRFTAEVVGTFILVFFGPGAAVITLMIANGADKPNEFNIGIGALGGLGDWFAIGM 61 Query: 76 CFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYL 135 F L+IA ++ G ISG HINPAVT+A+ + + V YI AQ +GA +G+ + Sbjct: 62 AFALAIAAVIYSLGRISGAHINPAVTIALWSIGRFPGREVVPYIVAQFIGAALGSLLFLA 121 Query: 136 VTPP--SVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAI 193 P + VGGLG T + G +L E I TF L+ I +R G L I Sbjct: 122 CVGPAAATVGGLGATAPFPGIGYGQAILTEAIGTFLLMLVIMGVAVDERAPP-GFAGLVI 180 Query: 194 GFSVAIGHLFAINYTGASMNPARSFGPAV-----IMGNWENHWIYWVGPIIGAVLAGALY 248 G +V N TG+S+NPAR+FGP + + W+ IY +GPI+GAV A LY Sbjct: 181 GLTVGGIITTIGNITGSSLNPARTFGPYLGDSLMGINLWQYFPIYVIGPIVGAVAAAWLY 240 Query: 249 EYV 251 Y+ Sbjct: 241 NYL 243 Score = 45.4 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 46/129 (35%), Gaps = 11/129 (8%) Query: 13 CGPPCSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVL 72 GP + + A + +A+ E + + +L+ +G ++ Sbjct: 123 VGPAAATVGGLGATAPFPGIGYGQAILTEAIGTFLLMLVIMGVAVDERAPPGFA------ 176 Query: 73 ISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKS----VFYITAQCLGAII 128 L GL++ ++ G+I+G +NPA T + Y+ +GA+ Sbjct: 177 -GLVIGLTVGGIITTIGNITGSSLNPARTFGPYLGDSLMGINLWQYFPIYVIGPIVGAVA 235 Query: 129 GAGILYLVT 137 A + + Sbjct: 236 AAWLYNYLA 244 >1LDI-A nrPDB Length = 281 Score = 181 bits (459), Expect = 4e-46, Method: Composition-based stats. Identities = 64/247 (25%), Positives = 95/247 (38%), Gaps = 34/247 (13%) Query: 38 VTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHIN 97 AEFL + + VG + IS+ +GL +A + +SG H+N Sbjct: 11 CIAEFLGTGLLIFFGVGCVAALKVA--GASFGQWEISVIWGLGVAMAIYLTAGVSGAHLN 68 Query: 98 PAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLV----------TPPSVVG---- 143 PAVT+A+ K + +I +Q GA A ++Y + T V G Sbjct: 69 PAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRGSVES 128 Query: 144 ----GLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGS-VALAIGFSVA 198 G T + ++ VE++IT L+ I A D G L IG +A Sbjct: 129 VDLAGTFSTYPNPHINFVQAFAVEMVITAILMGLILALTDDGNGVPRGPLAPLLIGLLIA 188 Query: 199 IGHLFAINYTGASMNPARSFGPAVIM--GNWEN-----------HWIYWVGPIIGAVLAG 245 + TG +MNPAR FGP V W N + GPI+GA++ Sbjct: 189 VIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGPIVGAIVGA 248 Query: 246 ALYEYVF 252 Y + Sbjct: 249 FAYRKLI 255 >2W1P-A nrPDB Length = 279 Score = 181 bits (458), Expect = 5e-46, Method: Composition-based stats. Identities = 70/219 (31%), Positives = 106/219 (48%), Gaps = 10/219 (4%) Query: 37 AVTAEFLAMLIFVL--LSVGSTINWGGSENPL---PVDMVLISLCFGLSIATMVQCFGHI 91 A++ EF+ +F+ + N P +++IS FG + V + Sbjct: 47 AMSGEFVGTFLFLWSAFVIAQIANQAPETPDGGSNPAQLIMISFGFGFGVMVGVFITYRV 106 Query: 92 SGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVH 151 SGG++NPAVT+A+V R I + + Q + + AG +TP + + Sbjct: 107 SGGNLNPAVTLALVLARAIPPFRGILMAFTQIVAGMAAAGAASAMTPGEIA---FANALG 163 Query: 152 GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYTGAS 211 G + GL +E T L T+ K T IG ++ I HL I YTGA Sbjct: 164 GGASRTRGLFLEAFGTAILCLTVLMLAVEKHRA-TWFAPFVIGIALLIAHLICIYYTGAG 222 Query: 212 MNPARSFGPAVIMGNWEN-HWIYWVGPIIGAVLAGALYE 249 +NPARSFGPAV ++ N HWIYW+GPI+GA LA ++++ Sbjct: 223 LNPARSFGPAVAARSFPNYHWIYWLGPILGAFLAYSIWQ 261 >3LLQ-A nrPDB Length = 256 Score = 180 bits (456), Expect = 9e-46, Method: Composition-based stats. Identities = 67/224 (29%), Positives = 108/224 (48%), Gaps = 12/224 (5%) Query: 36 KAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGH 95 + + AEF V GS + + + L + ++L FGL++ TM G ISGGH Sbjct: 31 RKLLAEFFGTFWLVFGGCGSAV-FAAAFPELGIGFTGVALAFGLTVLTMAYAVGGISGGH 89 Query: 96 INPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSV---VGGLGVTTVH- 151 NPAV+V + + + V Y+ AQ GAI+ A LY++ +GG Sbjct: 90 FNPAVSVGLTVAGRFPASSLVPYVIAQVAGAIVAAAALYVIATGKAGIDLGGFASNGYGE 149 Query: 152 ---GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAINYT 208 G + LL+E+I+T + I S + G +AIG ++ + HL +I T Sbjct: 150 HSPGGYSLVSALLIEIILTAFFLIVILGSTHGR--VPAGFAPIAIGLALTLIHLISIPVT 207 Query: 209 GASMNPARSFGPAVIMGNW--ENHWIYWVGPIIGAVLAGALYEY 250 S+NPARS G A+ +G W + W++W+ PI+G +++ Sbjct: 208 NTSVNPARSTGQALFVGGWALQQLWLFWLAPIVGGAAGAVIWKL 251 Score = 31.6 bits (70), Expect = 0.44, Method: Composition-based stats. Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 5/94 (5%) Query: 147 VTTVHGNLTAGHGLLVELIITFQLVFT-----IFASCDSKRTDVTGSVALAIGFSVAIGH 201 + G LL E TF LVF +FA+ + VALA G +V Sbjct: 20 ENLYFQSYVMGRKLLAEFFGTFWLVFGGCGSAVFAAAFPELGIGFTGVALAFGLTVLTMA 79 Query: 202 LFAINYTGASMNPARSFGPAVIMGNWENHWIYWV 235 +G NPA S G V + + +V Sbjct: 80 YAVGGISGGHFNPAVSVGLTVAGRFPASSLVPYV 113 >2O9F-A nrPDB Length = 234 Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats. Identities = 68/229 (29%), Positives = 107/229 (46%), Gaps = 14/229 (6%) Query: 35 WKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGG 94 ++ + AE V GS + G L + ++L FGL++ TM GHISGG Sbjct: 5 FRKLAAESFGTFWLVFGGSGSAVLAAGFPE-LGIGFAGVALAFGLTVLTMAFAVGHISGG 63 Query: 95 HINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILYLVTPPSVVGGLGVTTVH--- 151 H NPAVT+ + + + V Y+ AQ +G I+ A +LYL+ + Sbjct: 64 HFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNG 123 Query: 152 ------GNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIGFSVAIGHLFAI 205 G + L+VEL+++ + I + D + G +AIG + + HL +I Sbjct: 124 YGEHSPGGYSMLSALVVELVLSAGFLLVIHGATD--KFAPAGFAPIAIGLACTLIHLISI 181 Query: 206 NYTGASMNPARSFGPAVIMGNW--ENHWIYWVGPIIGAVLAGALYEYVF 252 T S+NPARS A+ G W E W +WV PI+G ++ G +Y + Sbjct: 182 PVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLL 230 >4AGS-A nrPDB Length = 471 Score = 31.9 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 22/64 (34%) Query: 230 HWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVET 289 H + P++GA LY +FCP V+ R E + + + Sbjct: 238 HLVPESAPMMGANGGHVLYSNLFCPFVDRARLASELRKFQMHIVEVPLHPQPEWYKYINP 297 Query: 290 EDLI 293 D + Sbjct: 298 RDTV 301 >4QGK-A nrPDB Length = 461 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 218 FGPAVIMGNWENHWIYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQT 273 G +I+G W ++ + P+IGA+ AG V EL + +K Q Sbjct: 103 LGVVLIIGAWNYPFVLTIQPLIGAIAAG---NAVIIKPSELSENTAKILAKLLPQY 155 >5Z7D-A nrPDB Length = 412 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 30/63 (47%) Query: 66 LPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLG 125 +P +++ IS FG + + +S ++NP + ++ ++ + + Y+ +Q G Sbjct: 269 IPRNIIAISDYFGCNGFLEIYRASCVSDVNVNPTMVISNTLRQRANATPKISYLFSQARG 328 Query: 126 AII 128 + Sbjct: 329 TFV 331 >5YZW-A nrPDB Length = 201 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 30/63 (47%) Query: 66 LPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLG 125 +P +++ IS FG + + +S ++NP + ++ ++ + + Y+ +Q G Sbjct: 58 IPRNIIAISDYFGCNGFLEIYRASCVSDVNVNPTMVISNTLRQRANATPKISYLFSQARG 117 Query: 126 AII 128 + Sbjct: 118 TFV 120 >5XEX-A nrPDB Length = 559 Score = 29.2 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 25/62 (40%), Gaps = 2/62 (3%) Query: 232 IYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETED 291 I + GPI G + +Y+ P VE + K + VE S++ ++ Sbjct: 143 IPFQGPIAGVNVGYIDGKYIINPTVE--EKEVSRLDLEVAGHKDAVNMVEAGASEITEQE 200 Query: 292 LI 293 ++ Sbjct: 201 ML 202 >3SBG-A nrPDB Length = 565 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%) Query: 232 IYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETED 291 I+ + P G + ++ V+ L + K ++ S + E + + T Sbjct: 47 IFTLNPKTGHLFLKIIHTSVWAGQKRLSQLAKWKTAEEVSALVRSLPKEEQPKQIIVTRK 106 Query: 292 LILKPGVVHVID 303 +L P VH++D Sbjct: 107 AMLDPLEVHMLD 118 >3E66-A nrPDB Length = 282 Score = 28.9 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 29/72 (40%) Query: 232 IYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETED 291 I+ + P G + ++ V+ L + K ++ S + E + + T Sbjct: 66 IFTLNPKTGHLFLKIIHTSVWAGQKRLSQLAKWKTAEEVSALVRSLPKEEQPKQIIVTRK 125 Query: 292 LILKPGVVHVID 303 +L P VH++D Sbjct: 126 AMLDPLEVHMLD 137 >5YJJ-A nrPDB Length = 713 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%), Gaps = 2/62 (3%) Query: 232 IYWVGPIIGAVLAGALYEYVFCPDVELKRRLKEAFSKAAQQTKGSYMEVEDNRSQVETED 291 I + GPI G + +YV P V + K + VE S++ + Sbjct: 155 IPFQGPIAGVNVGYIDGKYVINPSV--ADKEISRLDLEVAGHKDAVNMVEAGASEITESE 212 Query: 292 LI 293 ++ Sbjct: 213 ML 214 >2OZU-A nrPDB Length = 284 Score = 28.5 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 17/37 (45%), Gaps = 3/37 (8%) Query: 7 ARRWGKCGPPCSRESIMVAFKGVWTQAFWKAVTAEFL 43 ++R G+ G P S + A+WK+V E L Sbjct: 174 SKREGQAGSPEKPLSDLGRLS---YMAYWKSVILECL 207 >4Z3P-A nrPDB Length = 499 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 23/163 (14%), Positives = 50/163 (30%), Gaps = 1/163 (0%) Query: 15 PPCSRESIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSVGSTINWGGSENPLPVDMVLIS 74 P ++ F G + + F+ ML V ++ + + + Sbjct: 13 PNDELFTVAGMFDGSLYKLLLRMALPMFVGMLTQVTYAIADIFWLSHIDVTNSGIIAGVG 72 Query: 75 LCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYITAQCLGAIIGAGILY 134 L F + + G G + + M + SV I A AI+ + Y Sbjct: 73 LVFPVGMGLFAIANGIQIGMGSLLSRAIGMQRLDRAQRILSVGIIIA-LFFAIVITVLGY 131 Query: 135 LVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFAS 177 + P + ++ G T + + + + L+ + Sbjct: 132 VYAQPLLRSLGATKSIIGYATEFYYYSLLTVFSIMLIGVMMGL 174 >4PPM-A nrPDB Length = 861 Score = 27.7 bits (60), Expect = 7.1, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 38/104 (36%), Gaps = 1/104 (0%) Query: 135 LVTPPSVVGGLGVTTVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSVALAIG 194 + S GG + +V L +L+ + + F S+ V+ G Sbjct: 674 FLVHSSTYGGGNLASVVALSALREILAQDLVGHAERMGAYFKQALSEIAARYPFVSEVRG 733 Query: 195 FSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPI 238 + +G F +TGA AR F + G+W W + P+ Sbjct: 734 RGLMLGIQFDQAFTGAVNASAREFATRL-PGDWHTTWKFLPDPV 776 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.135 0.361 Lambda K H 0.267 0.0417 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,542,962 Number of Sequences: 36641 Number of extensions: 411513 Number of successful extensions: 1196 Number of sequences better than 10.0: 42 Number of HSP's better than 10.0 without gapping: 47 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1008 Number of HSP's gapped (non-prelim): 80 length of query: 323 length of database: 10,336,785 effective HSP length: 97 effective length of query: 226 effective length of database: 6,782,608 effective search space: 1532869408 effective search space used: 1532869408 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.3 bits)