BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P47103 (393 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5JHE-A nrPDB 811 0.0 1IHG-A nrPDB 179 2e-45 5YZG-3 nrPDB 152 2e-37 2WFI-A nrPDB 147 1e-35 2HE9-A nrPDB 145 3e-35 1C5F-A nrPDB 144 6e-35 2POY-A nrPDB 139 2e-33 5YB9-A nrPDB 136 2e-32 2HQJ-A nrPDB 134 5e-32 1XQ7-A nrPDB 133 2e-31 4JCP-A nrPDB 132 3e-31 4E1Q-A nrPDB 128 5e-30 2MC9-A nrPDB 128 5e-30 4JJM-A nrPDB 128 5e-30 4HY7-A nrPDB 127 6e-30 2HAQ-A nrPDB 127 9e-30 3R49-A nrPDB 125 2e-29 1E8K-A nrPDB 124 7e-29 5O9Z-M nrPDB 123 1e-28 6HMZ-X nrPDB 122 3e-28 1IST-A nrPDB 122 4e-28 1QNH-A nrPDB 121 5e-28 3ICH-A nrPDB 121 6e-28 3PMP-A nrPDB 120 1e-27 3RDD-A nrPDB 119 2e-27 2CFE-A nrPDB 119 3e-27 5TA2-A nrPDB 118 4e-27 5MQF-o nrPDB 115 3e-26 1H0P-A nrPDB 115 5e-26 4EYV-A nrPDB 114 8e-26 3UCH-A nrPDB 114 1e-25 2ESL-A nrPDB 111 5e-25 2RMC-A nrPDB 110 1e-24 4I9Y-A nrPDB 108 3e-24 6HIX-BZ nrPDB 107 9e-24 2CMT-A nrPDB 107 1e-23 6HIX-BQ nrPDB 103 1e-22 3JB9-d nrPDB 103 2e-22 2C3B-A nrPDB 101 7e-22 1Z81-A nrPDB 99 4e-21 5YZG-2 nrPDB 98 8e-21 3K2C-A nrPDB 97 2e-20 1XWN-A nrPDB 96 2e-20 2K7N-A nrPDB 96 2e-20 2A2N-A nrPDB 96 3e-20 2FU0-A nrPDB 89 3e-18 2OK3-A nrPDB 87 1e-17 2B71-A nrPDB 84 1e-16 2QER-A nrPDB 80 1e-15 1W74-A nrPDB 78 6e-15 5Z56-z nrPDB 71 8e-13 4R3E-A nrPDB 67 1e-11 2HQ6-A nrPDB 66 2e-11 1ZKC-A nrPDB 66 3e-11 4R3F-A nrPDB 66 3e-11 3BO7-A nrPDB 61 7e-10 3T1U-A nrPDB 61 9e-10 2MVZ-A nrPDB 58 8e-09 5OMP-A nrPDB 57 2e-08 1KT1-A nrPDB 57 2e-08 3S6M-A nrPDB 56 3e-08 2NUL-A nrPDB 53 2e-07 1QZ2-A nrPDB 53 2e-07 2OSE-A nrPDB 50 1e-06 3BKP-A nrPDB 50 2e-06 2IF4-A nrPDB 47 2e-05 5EX1-A nrPDB 43 2e-04 5EX2-A nrPDB 43 2e-04 5JJT-A nrPDB 41 0.001 2Y4T-A nrPDB 38 0.006 1A17-A nrPDB 38 0.009 4JA9-A nrPDB 37 0.012 5MGX-E nrPDB 36 0.033 1VAI-A nrPDB 34 0.088 4B4Y-A nrPDB 30 1.7 1W3B-A nrPDB 30 2.7 6FO1-G nrPDB 29 2.8 4I80-A nrPDB 28 5.2 >5JHE-A nrPDB Length = 397 Score = 811 bits (2095), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/393 (100%), Positives = 393/393 (100%) Query: 1 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN Sbjct: 5 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 64 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL Sbjct: 65 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 124 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD Sbjct: 125 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 184 Query: 181 SDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAA 240 SDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAA Sbjct: 185 SDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAA 244 Query: 241 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL 300 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL Sbjct: 245 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL 304 Query: 301 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN 360 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN Sbjct: 305 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN 364 Query: 361 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS 393 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS Sbjct: 365 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS 397 >1IHG-A nrPDB Length = 370 Score = 179 bits (453), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 129/391 (32%), Positives = 188/391 (48%), Gaps = 36/391 (9%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P V+ D+ I + +GRIV +LF + PKT ENF LC G+ + L +KG FH Sbjct: 15 NPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPFH 74 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 123 R++K FMIQ GD S+ G GG SIY +K E DE+F Y + E L Sbjct: 75 RIIKKFMIQGGDF---------SNQNGTGGESIYGEKFE----DENFHY-KHDKEGL--- 117 Query: 124 VEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDG 183 L MAN GS NTN SQFFITT PHL+GKH +FGQV+ G V + +EN V + Sbjct: 118 -----LSMANAGS-NTNGSQFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKGE- 170 Query: 184 VPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDD-DTHFGDDDFGKALEAANI 242 P I++CG ++ ++ GD + ++P+D D D D K L + Sbjct: 171 KPAKLCVIAECGELKEGDDWGIFPKDGS---GDSHPDFPEDADVDLKDVD--KILLISED 225 Query: 243 IKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVL 302 +K G FK +++ A KY K L Y+ + +Q + L LN+ Sbjct: 226 LKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVAL--SCVLNIGACK 283 Query: 303 FNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPD 362 + + A+ LE+D KA YRR + K D+AL D +E P+ Sbjct: 284 LKMSDWQGAVDSCLEALEID----PSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPE 339 Query: 363 DEVIEQRIEYVNRLIEENKEKTRKNISKFFS 393 D+ I+ + V + I+ K+K + +K F+ Sbjct: 340 DKAIQAELLKVKQKIKAQKDKEKAAYAKMFA 370 >5YZG-3 nrPDB Length = 754 Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 85/195 (43%), Positives = 111/195 (56%), Gaps = 25/195 (12%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 +Q P + DI+I+ +P GR+V +LF + PKT ENF LC G+ + Q+ L YK Sbjct: 5 VQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCL 64 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVVK+FM+Q GD G G+GG SIY G FEDE+ Sbjct: 65 FHRVVKDFMVQGGDFSEGN---------GRGGESIYG--------------GFFEDESFA 101 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + + F L MAN G +TN SQFFITT PHL+G H +FGQV+ G+ VVR IEN + D Sbjct: 102 VKHNKEFLLSMANRGK-DTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTD 160 Query: 181 SDGVPESDVRISDCG 195 + P ++VRI CG Sbjct: 161 AASKPFAEVRILSCG 175 >2WFI-A nrPDB Length = 179 Score = 147 bits (370), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 85/195 (43%), Positives = 111/195 (56%), Gaps = 25/195 (12%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 +Q P + DI+I+ +P GR+V +LF + PKT ENF LC G+ + Q+ L YK Sbjct: 7 VQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCL 66 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVVK+FM+Q GD S G+GG SIY G FEDE+ Sbjct: 67 FHRVVKDFMVQGGDF---------SEGNGRGGESIYG--------------GFFEDESFA 103 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + + F L MAN G +TN SQFFITT PHL+G H +FGQV+ G+ VVR IEN + D Sbjct: 104 VKHNKEFLLSMANRGK-DTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTD 162 Query: 181 SDGVPESDVRISDCG 195 + P ++VRI CG Sbjct: 163 AASKPFAEVRILSCG 177 >2HE9-A nrPDB Length = 192 Score = 145 bits (367), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 86/195 (44%), Positives = 111/195 (56%), Gaps = 25/195 (12%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 P + DI I+++P+GRI+ +LF + PKT +NF LC+G+ + L YKG+ FH Sbjct: 19 SPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFH 78 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-LGE 122 RVVKNFMIQ GD S GKGG SIY G F+DEN + + Sbjct: 79 RVVKNFMIQGGDF---------SEGNGKGGESIYG--------------GYFKDENFILK 115 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 F L MAN G +TN SQFFITT APHL+G H +FG V+ G V+ IEN + D+ Sbjct: 116 HDRAFLLSMANRGK-HTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAA 174 Query: 183 GVPESDVRISDCGVW 197 P +DVR+ DCGV Sbjct: 175 SRPYADVRVIDCGVL 189 >1C5F-A nrPDB Length = 177 Score = 144 bits (364), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 89/193 (46%), Positives = 110/193 (56%), Gaps = 31/193 (16%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 V+LD++ID GRIV +L+ + AP+T NF LC G + + L YKG+ FHRV+ Sbjct: 9 VFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLMLCTGMAGTGKISGKPLHYKGSTFHRVI 68 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFV-- 124 KNFMIQ GD T+ D G GG SIY G F+DE EFV Sbjct: 69 KNFMIQGGDF---TKGD------GTGGESIYG--------------GMFDDE---EFVMK 102 Query: 125 --EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 EPF + MAN G PNTN SQFFITT APHLN H +FG+VV G+ VV IE + +S Sbjct: 103 HDEPFVVSMANKG-PNTNGSQFFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNSK 161 Query: 183 GVPESDVRISDCG 195 P +DV I +CG Sbjct: 162 NRPLADVVILNCG 174 >2POY-A nrPDB Length = 186 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 88/197 (44%), Positives = 108/197 (54%), Gaps = 33/197 (16%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P+VY DISI + P GRI +LF +K P T ENF LC G+ K + + L Y G+ FH Sbjct: 19 NPVVYFDISIGQTPAGRITMELFADKVPITAENFRALCTGE-KGMGQSGKPLCYTGSFFH 77 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 123 R++ FMIQ GD T+ D G GG SIY K F DEN F Sbjct: 78 RIIPQFMIQGGDF---TRGD------GTGGESIYGSK--------------FRDEN---F 111 Query: 124 V----EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 V PF L MAN G PNTN SQFFITT P L+GKH +FG+V+ G VV++IE C Sbjct: 112 VYTHDAPFLLSMANAG-PNTNGSQFFITTVPCPWLDGKHVVFGKVLEGMEVVKSIEKCG- 169 Query: 180 DSDGVPESDVRISDCGV 196 +G P V I+ GV Sbjct: 170 SQNGKPTKSVCITASGV 186 >5YB9-A nrPDB Length = 175 Score = 136 bits (342), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 83/195 (42%), Positives = 108/195 (55%), Gaps = 25/195 (12%) Query: 1 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 M++ P + DISI +G+IV +LF + PKT ENF LC G+ K K LSYKG Sbjct: 3 MLKRPKTFFDISIRGDKVGKIVFELFNDIVPKTAENFRALCTGE-KGIGKSGMPLSYKGT 61 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 FHR++ FMIQ GD + G GG SIY +K DDE+F Sbjct: 62 MFHRIIPQFMIQGGDF---------TRFNGTGGESIYG----MKFDDENFKV-------- 100 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + +P L MAN G PNTN SQFFITT P L+G H +FGQV+ G +V+ IE+C + Sbjct: 101 -KHDKPGLLSMANAG-PNTNGSQFFITTVETPWLDGHHCVFGQVIEGMDIVKQIESCGTE 158 Query: 181 SDGVPESDVRISDCG 195 S G P + ++DCG Sbjct: 159 S-GRPRAMCMVTDCG 172 >2HQJ-A nrPDB Length = 183 Score = 134 bits (338), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 85/194 (43%), Positives = 104/194 (53%), Gaps = 22/194 (11%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ DISID K GRIV +L+ + PKT ENF LC G+ K + + L YK + Sbjct: 5 MTNPKVFFDISIDNKAAGRIVMELYADTVPKTAENFRALCTGE-KGKGRSGKPLHYKSSV 63 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ NFMIQ GD G G GG SIY DESF LG Sbjct: 64 FHRVIPNFMIQGGDFTRGN---------GTGGESIYGTTFR----DESFSGKAGRHTGLG 110 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 L MAN G PNTN SQFFI T A P L+GKH +FG+V+ G VV+ +E S Sbjct: 111 ------CLSMANAG-PNTNGSQFFICTAATPWLDGKHVVFGRVIDGLDVVKKVERLG-SS 162 Query: 182 DGVPESDVRISDCG 195 G S + +SDCG Sbjct: 163 SGKTRSRIVVSDCG 176 >1XQ7-A nrPDB Length = 166 Score = 133 bits (334), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 81/192 (42%), Positives = 107/192 (55%), Gaps = 36/192 (18%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 VY DI+I +P+GR+V LF PKT ENF +L +G + YKG+ FHRV+ Sbjct: 8 VYFDITIGDEPVGRVVIGLFGNDVPKTVENFKQLASG--------ENGFGYKGSIFHRVI 59 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG--EFV 124 +NFMIQ GD T D G GG SIY + F+DENL FV Sbjct: 60 RNFMIQGGDF---TNFD------GTGGKSIYGTR--------------FDDENLKIKHFV 96 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 + MAN G PN+N SQFF+TT P L+G+H +FG+VV G VV+ +EN + + Sbjct: 97 G--AVSMANAG-PNSNGSQFFVTTAPTPWLDGRHVVFGKVVEGMDVVKKVENTKTGLNDK 153 Query: 185 PESDVRISDCGV 196 P+ V+I+DCGV Sbjct: 154 PKKAVKINDCGV 165 >4JCP-A nrPDB Length = 175 Score = 132 bits (331), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 82/195 (42%), Positives = 105/195 (53%), Gaps = 27/195 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + P V+ DI+I GRIV +LF + PKT ENF LC G+ + + + L YKG+ Sbjct: 5 MSRPKVFFDITIGGSNAGRIVMELFADIVPKTAENFRCLCTGE-RGMGRSGKKLHYKGSK 63 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ NFM+Q GD G G GG SIY +K F DEN Sbjct: 64 FHRVIPNFMLQGGDFTRGN---------GTGGESIYGEK--------------FPDENFQ 100 Query: 122 E-FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 E P L MAN G PNTN SQFFI T L+GKH +FG+VV G +VV+ +E+ + Sbjct: 101 EKHTGPGVLSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGRVVEGMNVVKAVES-KGS 158 Query: 181 SDGVPESDVRISDCG 195 G +D+ ISDCG Sbjct: 159 QSGRTSADIVISDCG 173 >4E1Q-A nrPDB Length = 207 Score = 128 bits (321), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 106/195 (54%), Gaps = 27/195 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+++ P GRIV +L+++ P+T ENF LC G+ K K + L YKG+ Sbjct: 37 MANPRVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGE-KGVGKSGKPLHYKGSA 95 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ +FM Q GD G G GG SIY +K DE F + Sbjct: 96 FHRVIPDFMCQGGDFTRGN---------GTGGESIYGEK----FADEKFVH--------- 133 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 + +P L MAN G PNTN SQFFI T L+GKH +FG+VV G VV+ IE +V S Sbjct: 134 KHTKPGILSMANAG-PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE--KVGS 190 Query: 182 -DGVPESDVRISDCG 195 G V I+DCG Sbjct: 191 RSGTCSKQVVIADCG 205 >2MC9-A nrPDB Length = 178 Score = 128 bits (321), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 100/195 (51%), Gaps = 27/195 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+S+ +P GRIV +LF + P+T ENF LC G+ K + + L YK + Sbjct: 7 MPNPRVFFDMSVGGQPAGRIVMELFADTTPRTAENFRALCTGE-KGTGRSGKPLHYKDSS 65 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-L 120 FHRV+ FM Q GD G G GG SIY K F DEN + Sbjct: 66 FHRVIPGFMCQGGDFTAGN---------GTGGESIYGAK--------------FADENFI 102 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFFI T L+GKH +FGQVV G VV+ IE Sbjct: 103 KKHTGPGILSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGQVVEGMDVVKAIEKVG-S 160 Query: 181 SDGVPESDVRISDCG 195 S G V + DCG Sbjct: 161 SSGRTAKKVVVEDCG 175 >4JJM-A nrPDB Length = 175 Score = 128 bits (321), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 101/195 (51%), Gaps = 27/195 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+++ +P GRIV +LF + P+T ENF LC G+ K K + L YKG+ Sbjct: 4 MPNPKVFFDMTVGGQPAGRIVMELFADVTPRTAENFRALCTGE-KGIGKSGKPLHYKGSS 62 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-L 120 FHRV+ FM Q GD G G GG SIY K F DEN + Sbjct: 63 FHRVIPGFMCQGGDFTAGN---------GTGGESIYGSK--------------FADENFV 99 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G P TN SQFF+ T L+GKH +FGQVV G VV+ IE Sbjct: 100 KKHTGPGILSMANAG-PGTNGSQFFVCTAKTEWLDGKHVVFGQVVEGMDVVKAIEKVG-S 157 Query: 181 SDGVPESDVRISDCG 195 S G V I+DCG Sbjct: 158 SSGRTNKPVVIADCG 172 >4HY7-A nrPDB Length = 171 Score = 127 bits (320), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 80/195 (41%), Positives = 106/195 (54%), Gaps = 27/195 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+++ P GRIV +L+++ P+T ENF LC G+ K K + L YKG+ Sbjct: 1 MANPRVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGE-KGVGKSGKPLHYKGSA 59 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ +FM Q GD G G GG SIY +K DE F + Sbjct: 60 FHRVIPDFMCQGGDFTRGN---------GTGGESIYGEK----FADEKFVH--------- 97 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 + +P L MAN G PNTN SQFFI T L+GKH +FG+VV G VV+ IE +V S Sbjct: 98 KHTKPGILSMANAG-PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIE--KVGS 154 Query: 182 -DGVPESDVRISDCG 195 G V I+DCG Sbjct: 155 RSGTCSKQVVIADCG 169 >2HAQ-A nrPDB Length = 172 Score = 127 bits (319), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 83/191 (43%), Positives = 101/191 (52%), Gaps = 36/191 (18%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 VY D+ ID +P+GRI LF + AP TTENF +LC G + YK + FHRV+ Sbjct: 14 VYFDVMIDSEPLGRITIGLFGKDAPLTTENFRQLCTG--------EHGFGYKDSIFHRVI 65 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG--EFV 124 +NFMIQ GD T D G GG SIY +K F DENL FV Sbjct: 66 QNFMIQGGDF---TNFD------GTGGKSIYGEK--------------FADENLNVKHFV 102 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 L MAN G PNTN SQFFITT P L+G+H +FG+V+ G VV IE + +S Sbjct: 103 G--ALSMANAG-PNTNGSQFFITTAPTPWLDGRHVVFGKVLDGMDVVLRIEKTKTNSHDR 159 Query: 185 PESDVRISDCG 195 P V+I G Sbjct: 160 PVKPVKIVASG 170 >3R49-A nrPDB Length = 166 Score = 125 bits (315), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 80/196 (40%), Positives = 103/196 (52%), Gaps = 34/196 (17%) Query: 1 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 M +PLVYLD+ + KP+GR+V +L + PKT ENF LC G ++ YKG+ Sbjct: 1 MSGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTG--------EKGFGYKGS 52 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 FHRV+ +FM QAGD ++ G GG SIY + F DEN Sbjct: 53 TFHRVIPSFMCQAGDF---------TNHNGTGGKSIYGSR--------------FPDENF 89 Query: 121 G-EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 + V P L MAN G PNTN SQFFI T L+GKH +FG V+ G VV+ IE+ Sbjct: 90 TLKHVGPGVLSMANAG-PNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGS 148 Query: 180 DSDGVPESDVRISDCG 195 S G + I+DCG Sbjct: 149 KS-GRTSKKIVITDCG 163 >1E8K-A nrPDB Length = 173 Score = 124 bits (311), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 80/190 (42%), Positives = 100/190 (52%), Gaps = 27/190 (14%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 V+ DI+I K GRIV +L+ + PKT NF LC G+ K + L +KG+ FHR++ Sbjct: 6 VFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGE-NGIGKSGKPLHFKGSKFHRII 64 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE-FVE 125 NFMIQ GD G G GG SIY +K F DEN E Sbjct: 65 PNFMIQGGDFTRGN---------GTGGESIYGEK--------------FPDENFKEKHTG 101 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVP 185 P L MAN G PNTN SQFF+ T L+GKH +FG+VV G VV+ +E+ S G P Sbjct: 102 PGVLSMANAG-PNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQS-GKP 159 Query: 186 ESDVRISDCG 195 D I+DCG Sbjct: 160 VKDCMIADCG 169 >5O9Z-M nrPDB Length = 177 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 77/193 (39%), Positives = 102/193 (52%), Gaps = 28/193 (14%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P+V+ D+SI + +GR+ +LF + PKT ENF + C G+ + KD + YKG+ FH Sbjct: 10 NPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFR---KDGVPIGYKGSTFH 66 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-E 122 RV+K+FMIQ GD V G G G SIY G F DEN Sbjct: 67 RVIKDFMIQGGDFVNGD---------GTGVASIY--------------RGPFADENFKLR 103 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P L MAN G P+TN QFFIT L+GKH +FG+++ G V+R IEN + Sbjct: 104 HSAPGLLSMANSG-PSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPN 162 Query: 183 GVPESDVRISDCG 195 P+ V IS CG Sbjct: 163 NKPKLPVVISQCG 175 >6HMZ-X nrPDB Length = 180 Score = 122 bits (306), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 80/196 (40%), Positives = 104/196 (53%), Gaps = 29/196 (14%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ DI I K GR+V +LF + P+T +NF LC G+ K + + L YKG+ Sbjct: 1 MANPKVFFDILIGKMKAGRVVMELFADVTPRTADNFRALCTGE-KGIGQAGKALHYKGSA 59 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHR++ FM Q GD G G GG SIY K F+DEN Sbjct: 60 FHRIIPGFMCQGGDFTRGN---------GTGGESIYGAK--------------FQDENFK 96 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFFI T L+GKH +FG+VV G +VV+ +E +V Sbjct: 97 LKHTGPGILSMANSG-PNTNGSQFFICTDKTAWLDGKHVVFGKVVDGYNVVKAME--KVG 153 Query: 181 SD-GVPESDVRISDCG 195 S+ GV V I DCG Sbjct: 154 SERGVTSEPVVIEDCG 169 >1IST-A nrPDB Length = 162 Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 75/190 (39%), Positives = 100/190 (52%), Gaps = 34/190 (17%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 VY D+ D +PIGR+V KL+ + PKT ENF LC G ++ Y G+ FHRV+ Sbjct: 4 VYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTG--------EKGFGYAGSPFHRVI 55 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVE- 125 +FM+Q GD G G GG SIY G F DEN + + Sbjct: 56 PDFMLQGGDFTAGN---------GTGGKSIYG--------------GKFPDENFKKHHDR 92 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVP 185 P L MAN G PNTN SQFFITT P L+GKH +FG+VV G +V+ +E+ S G Sbjct: 93 PGLLSMANAG-PNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLGSPS-GAT 150 Query: 186 ESDVRISDCG 195 ++ + ++ G Sbjct: 151 KARIVVAKSG 160 >1QNH-A nrPDB Length = 170 Score = 121 bits (304), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 81/193 (41%), Positives = 103/193 (53%), Gaps = 30/193 (15%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGD-VKSPLKDQQYLSYKGNGFHRV 65 V+ DISID GRI+ +LF + P+T ENF LC G+ + S K+ L YK + FHR+ Sbjct: 6 VFFDISIDNSNAGRIIFELFSDITPRTCENFRALCTGEKIGSRGKN---LHYKNSIFHRI 62 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 + FM Q GDI G G GG SIY +F DEN + Sbjct: 63 IPQFMCQGGDITNGN---------GSGGESIYGR--------------SFTDENFNMKHD 99 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 +P L MAN G PNTN+SQF IT P L+GKH +FG+V+ G +VVR +E S V Sbjct: 100 QPGLLSMANAG-PNTNSSQFLITLVPCPWLDGKHVVFGKVIEGMNVVREMEKEGAKSGYV 158 Query: 185 PESDVRISDCGVW 197 S V I+DCG W Sbjct: 159 KRS-VVITDCGEW 170 >3ICH-A nrPDB Length = 188 Score = 121 bits (303), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 75/189 (39%), Positives = 100/189 (52%), Gaps = 31/189 (16%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 VY D+ I + +GR++ LF + PKT +NF L G ++ YK + FHRV+ Sbjct: 18 VYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATG--------EKGFGYKNSKFHRVI 69 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEP 126 K+FMIQ GD G G GG SIY E F NF+ ++ G P Sbjct: 70 KDFMIQGGDFTRGD---------GTGGKSIYG---------ERFPDENFKLKHYG----P 107 Query: 127 FTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPE 186 + MAN G +TN SQFFITT L+GKH +FG+V+ G VVR +E+ + DS P Sbjct: 108 GWVSMANAGK-DTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPL 166 Query: 187 SDVRISDCG 195 DV I+DCG Sbjct: 167 KDVIIADCG 175 >3PMP-A nrPDB Length = 164 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 75/191 (39%), Positives = 101/191 (52%), Gaps = 34/191 (17%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 V+ +ISI+ KP GRIV KL+ E PKT +NF +L G Q YK + FHRV+ Sbjct: 5 VFFNISINDKPEGRIVFKLYDEAVPKTAKNFRELATG--------QHGFGYKDSIFHRVI 56 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFVE 125 FM+Q GD + G GG SIY +K F DEN + + Sbjct: 57 PQFMLQGGDF---------TRHNGTGGKSIYGEK--------------FADENFQVKHTK 93 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVP 185 P L MAN G+ NTN SQFFITT L+GKH +FG+V+ G +VR +E + + G Sbjct: 94 PGLLSMANAGA-NTNGSQFFITTVPTSWLDGKHVVFGEVIEGLDIVRKVEG-KGSASGKT 151 Query: 186 ESDVRISDCGV 196 + ++I+DCG Sbjct: 152 NATIKITDCGT 162 >3RDD-A nrPDB Length = 184 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 76/197 (38%), Positives = 103/197 (52%), Gaps = 36/197 (18%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P V+ DI++D +P+GR+ +LF +K PKT ENF L G ++ YKG+ FH Sbjct: 22 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTG--------EKGFGYKGSCFH 73 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-LGE 122 R++ FM Q GD + G GG SIY +K FEDEN + + Sbjct: 74 RIIPGFMCQGGDF---------TRHNGTGGKSIYGEK--------------FEDENFILK 110 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS- 181 P L MAN G PNTN SQFFI T L+GKH +FG+V G ++V +E R S Sbjct: 111 HTGPGILSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAME--RFGSR 167 Query: 182 DGVPESDVRISDCGVWE 198 +G + I+DCG E Sbjct: 168 NGKTSKKITIADCGQLE 184 >2CFE-A nrPDB Length = 162 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 76/191 (39%), Positives = 97/191 (50%), Gaps = 34/191 (17%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 V+ DI+ + P+G I KLF + PKT NF LC G ++ Y G+ FHRV+ Sbjct: 4 VFFDITKNGAPLGTIKFKLFDDVVPKTAANFRALCTG--------EKGFGYAGSHFHRVI 55 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFVE 125 +FM+Q GD G G GG SIY K F DEN + + Sbjct: 56 PDFMLQGGDFTAGN---------GTGGKSIYGAK--------------FADENFQLKHNK 92 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVP 185 P L MAN G PNTN SQFFITT L+GKH +FG+V+ G +VV+ IE G P Sbjct: 93 PGLLSMANAG-PNTNGSQFFITTVVTSWLDGKHVVFGEVIDGMNVVKAIE-AEGSGSGKP 150 Query: 186 ESDVRISDCGV 196 S + I+ CGV Sbjct: 151 RSRIEIAKCGV 161 >5TA2-A nrPDB Length = 163 Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 75/194 (38%), Positives = 102/194 (52%), Gaps = 36/194 (18%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P V+ DI++D +P+GR+ +LF +K PKT ENF L G ++ YKG+ FH Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTG--------EKGFGYKGSCFH 53 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-LGE 122 R++ FM Q GD + G GG SIY +K FEDEN + + Sbjct: 54 RIIPGFMCQGGDF---------TRHNGTGGKSIYGEK--------------FEDENFILK 90 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS- 181 P L MAN G PNTN SQFFI T L+GKH +FG+V G ++V +E R S Sbjct: 91 HTGPGILSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAME--RFGSR 147 Query: 182 DGVPESDVRISDCG 195 +G + I+DCG Sbjct: 148 NGKTSKKITIADCG 161 >5MQF-o nrPDB Length = 301 Score = 115 bits (288), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 75/193 (38%), Positives = 97/193 (50%), Gaps = 34/193 (17%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P VY+DI I KP GRI L + P T ENF LC ++ +KG+ FH Sbjct: 139 NPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCT--------HEKGFGFKGSSFH 190 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-LGE 122 R++ FM Q GD ++ G GG SIY K F+DEN + + Sbjct: 191 RIIPQFMCQGGDF---------TNHNGTGGKSIYGKK--------------FDDENFILK 227 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P L MAN G PNTN SQFF+T L+GKH +FG+V G V+R IE + D Sbjct: 228 HTGPGLLSMANSG-PNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIE-AQGSKD 285 Query: 183 GVPESDVRISDCG 195 G P+ V I+DCG Sbjct: 286 GKPKQKVIIADCG 298 >1H0P-A nrPDB Length = 182 Score = 115 bits (287), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 75/189 (39%), Positives = 96/189 (50%), Gaps = 31/189 (16%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 VY D+ I KPIGRIV LF + PKT NF +L K + Y G+ FHRV+ Sbjct: 9 VYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELA--------KKPKGEGYPGSKFHRVI 60 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEP 126 +FMIQ GD G G GG SIY +K F NF+ ++ G Sbjct: 61 ADFMIQGGDFTRGD---------GTGGRSIYGEK---------FADENFKLKHYGAG--- 99 Query: 127 FTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPE 186 L MAN G+ +TN SQFFITT P L+G+H +FG+++ G VVR IE P+ Sbjct: 100 -WLSMANAGA-DTNGSQFFITTVKTPWLDGRHVVFGKILEGMDVVRKIEQTEKLPGDRPK 157 Query: 187 SDVRISDCG 195 DV I+ G Sbjct: 158 QDVIIAASG 166 >4EYV-A nrPDB Length = 167 Score = 114 bits (285), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 76/195 (38%), Positives = 101/195 (51%), Gaps = 34/195 (17%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + P VY DISID + GRIV KL+ + P T +NF +L K+P Y G+ Sbjct: 4 MSQPNVYFDISIDNQNAGRIVFKLYDDVVPLTAKNFRELA----KNPAGQ----GYTGST 55 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHR++ FM+Q GD ++ G GG SIY +K F+DEN Sbjct: 56 FHRIIPQFMLQGGDF---------TNHNGTGGRSIYGNK--------------FKDENFQ 92 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + +P L MAN G P+TN SQFFITT L+GKH +FG+VV G VV+ +E Sbjct: 93 LKHTKPGLLSMANAG-PHTNGSQFFITTVVTSWLDGKHVVFGEVVEGMDVVKKVEAVGTQ 151 Query: 181 SDGVPESDVRISDCG 195 S G P V+I+ G Sbjct: 152 S-GKPSKVVKITASG 165 >3UCH-A nrPDB Length = 174 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 75/193 (38%), Positives = 97/193 (50%), Gaps = 34/193 (17%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P VY+DI I KP GRI L + P T ENF LC ++ +KG+ FH Sbjct: 12 NPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCT--------HEKGFGFKGSSFH 63 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN-LGE 122 R++ FM Q GD ++ G GG SIY K F+DEN + + Sbjct: 64 RIIPQFMCQGGDF---------TNHNGTGGKSIYGKK--------------FDDENFILK 100 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P L MAN G PNTN SQFF+T L+GKH +FG+V G V+R IE + D Sbjct: 101 HTGPGLLSMANSG-PNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIE-AQGSKD 158 Query: 183 GVPESDVRISDCG 195 G P+ V I+DCG Sbjct: 159 GKPKQKVIIADCG 171 >2ESL-A nrPDB Length = 190 Score = 111 bits (278), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 74/192 (38%), Positives = 98/192 (51%), Gaps = 37/192 (19%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 V+ D+ I K +GRIV LF + PKT ENF L G ++ YKG+ FHRV+ Sbjct: 18 VFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATG--------EKGYGYKGSKFHRVI 69 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEP 126 K+FMIQ GDI G G GG SIY + F DEN ++ Sbjct: 70 KDFMIQGGDITTGD---------GTGGVSIYGE--------------TFPDENFK--LKH 104 Query: 127 FTLG---MANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDG 183 + +G MAN G P+TN SQFFIT L+GKH +FG+V+ G +VV +IE D Sbjct: 105 YGIGWVSMANAG-PDTNGSQFFITLTKPTWLDGKHVVFGKVIDGMTVVHSIELQATDGHD 163 Query: 184 VPESDVRISDCG 195 P ++ I + G Sbjct: 164 RPLTNCSIINSG 175 >2RMC-A nrPDB Length = 182 Score = 110 bits (274), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 75/192 (39%), Positives = 98/192 (51%), Gaps = 37/192 (19%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 V+ D+ I K +GRIV LF PKT ENF L G ++ YKG+ FHRV+ Sbjct: 10 VFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATG--------EKGYGYKGSIFHRVI 61 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEP 126 K+FMIQ GD T +D G GG SIY + F DEN ++ Sbjct: 62 KDFMIQGGDF---TARD------GTGGMSIYGE--------------TFPDENFK--LKH 96 Query: 127 FTLG---MANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDG 183 + +G MAN G P+TN SQFFIT L+GKH +FG+V+ G +VV +IE D Sbjct: 97 YGIGWVSMANAG-PDTNGSQFFITLTKPTWLDGKHVVFGKVLDGMTVVHSIELQATDGHD 155 Query: 184 VPESDVRISDCG 195 P +D I + G Sbjct: 156 RPLTDCTIVNSG 167 >4I9Y-A nrPDB Length = 167 Score = 108 bits (271), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 77/199 (38%), Positives = 101/199 (50%), Gaps = 42/199 (21%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P+V+ D+ D +P+GRI +LF P+T ENF LC G ++ +K + Sbjct: 4 MTNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTG--------EKGFGFKNSI 55 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ +F+ Q GDI T+ D G GG SIY DK FEDEN Sbjct: 56 FHRVIPDFVCQGGDI---TKHD------GTGGQSIYGDK--------------FEDENFD 92 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G NTNNSQF IT A HL+ KH +FG V G V+ IE Sbjct: 93 VKHTGPGLLSMANQGQ-NTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIE----- 146 Query: 181 SDGVPESDV----RISDCG 195 S G P+ V I++CG Sbjct: 147 SFGSPKGSVCRRITITECG 165 >6HIX-BZ nrPDB Length = 190 Score = 107 bits (267), Expect = 9e-24, Method: Compositional matrix adjust. Identities = 75/205 (36%), Positives = 98/205 (47%), Gaps = 34/205 (16%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQ------------QY 54 ++DI+I K RIV KLF K P +NF +LC+G+V + + Sbjct: 7 AFMDIAIGTKAPRRIVFKLFPRKCPSAVKNFIELCSGNVSTDTYESGNRDKLISESALPQ 66 Query: 55 LSYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGN 114 L+YK + FHRV K ++IQ GDIV G + S G ++ EEV+ Sbjct: 67 LTYKNSTFHRVEKGYLIQGGDIVTGRGTEQLSIYGGT-----FSAPEEVRAS-------- 113 Query: 115 FEDENLGEFVEPFTLGMANLGSPNTNNSQFFI-TTYAAPHLNGKHSIFGQVVHGKSVVRT 173 F +P +G A+ SPN + SQFFI T A HLNG FGQV G VV+ Sbjct: 114 -------VFDKPGLVGTAS-SSPNAHGSQFFILTAKEANHLNGTCICFGQVADGLDVVQE 165 Query: 174 IENCRVDSDGVPESDVRISDCGVWE 198 IE +D G P V I DCGV E Sbjct: 166 IEQVPIDPSGFPSLKVSIVDCGVLE 190 >2CMT-A nrPDB Length = 172 Score = 107 bits (266), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 78/191 (40%), Positives = 94/191 (49%), Gaps = 32/191 (16%) Query: 5 PLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHR 64 P V+ DI I GRIV +L + P+T ENF LC G ++ Y FHR Sbjct: 11 PRVFFDIRIGNGDAGRIVMELRSDIVPRTAENFRALCTG--------ERGFGYHNCCFHR 62 Query: 65 VVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFV 124 V+ FM Q GD V G G GG SIY K DDE+F E G Sbjct: 63 VIPQFMCQGGDFVKGD---------GTGGKSIYGRK----FDDENF---QLRHEGFG--- 103 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 L MAN G PNTN SQFFI T L+GKH +FG+VV G++VV+ +E+ S V Sbjct: 104 ---VLSMANSG-PNTNGSQFFICTTKCDWLDGKHVVFGRVVDGQNVVKKMESVGSKSGKV 159 Query: 185 PESDVRISDCG 195 E V IS CG Sbjct: 160 KEP-VIISRCG 169 >6HIX-BQ nrPDB Length = 231 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 68/192 (35%), Positives = 100/192 (52%), Gaps = 24/192 (12%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P+V++D++++ +GR+ +LF + PKTTENF LC G+ Q L YKG FH Sbjct: 28 NPVVFMDVTVEGDALGRVSVELFHDIVPKTTENFRSLCTGERG---YSQCPLFYKGIPFH 84 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 123 RV+ F++Q GDI+ KD G+G S++ DESF + G+ Sbjct: 85 RVIPGFIVQGGDILL---KD------GRGNVSVFG----FPFPDESF------EGKAGKH 125 Query: 124 VEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDG 183 + T+ MA+ +PN N SQFF HL+GK + GQV+ G VV + S G Sbjct: 126 LRG-TVAMAH-SAPNQNGSQFFFNLARNDHLDGKFVVCGQVIDGWEVVDRVAVLSGSSCG 183 Query: 184 VPESDVRISDCG 195 P S I++CG Sbjct: 184 TPVSRAWITECG 195 >3JB9-d nrPDB Length = 155 Score = 103 bits (256), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 69/174 (39%), Positives = 91/174 (52%), Gaps = 34/174 (19%) Query: 18 IGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIV 77 +G+I+ +L+ E APKT +NFY L + Y Y G FHRV+ +F+IQ GD Sbjct: 10 LGKILIELYTEHAPKTCQNFYTLA---------KEGY--YDGVIFHRVIPDFVIQGGD-- 56 Query: 78 FGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSP 137 + G+GG SIY DK DDE + + G L MAN G P Sbjct: 57 --------PTGTGRGGTSIYGDK----FDDE--IHSDLHHTGAG------ILSMANAG-P 95 Query: 138 NTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRI 191 NTN+SQFFIT P L+GKH+IFG+VV G SV + + R DS P ++I Sbjct: 96 NTNSSQFFITLAPTPWLDGKHTIFGRVVSGLSVCKRMGLIRTDSSDRPIEPLKI 149 >2C3B-A nrPDB Length = 172 Score = 101 bits (251), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 76/193 (39%), Positives = 95/193 (49%), Gaps = 38/193 (19%) Query: 8 YLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVK 67 Y + + +GRIV LF + PKT +NF +LC K P + Y+ + FHR++ Sbjct: 11 YAPVGTAETKVGRIVFNLFDKDVPKTAKNFRELC----KRPAGE----GYRESTFHRIIP 62 Query: 68 NFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFVEP 126 NFMIQ GD G G GG SIY DK F DEN + + Sbjct: 63 NFMIQGGDFTRGN---------GTGGRSIYGDK--------------FADENFSRKHDKK 99 Query: 127 FTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGK--SVVRTIENCRVDSDGV 184 L MAN G PNTN SQFFITT L+GKH +FG+V K SVV+ IE S G Sbjct: 100 GILSMANAG-PNTNGSQFFITTAVTSWLDGKHVVFGEVADEKSYSVVKEIEALG-SSSGS 157 Query: 185 PESDVR--ISDCG 195 S+ R I +CG Sbjct: 158 VRSNTRPKIVNCG 170 >1Z81-A nrPDB Length = 229 Score = 99.0 bits (245), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 69/196 (35%), Positives = 104/196 (53%), Gaps = 29/196 (14%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 +P+V++DI++ +G+ +LF+ PKT+ENF + C G+ K + + YK F Sbjct: 58 SNPVVFMDINLGNNFLGKFKFELFQNIVPKTSENFRQFCTGEYKV---NNLPVGYKNTIF 114 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HRV+K FMIQ GD + + G G SIY + K DDE+F + + E L Sbjct: 115 HRVIKEFMIQGGDFI---------NHNGSGSLSIYGE----KFDDENFDIKH-DKEGL-- 158 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKS--VVRTIENCRVD 180 L MAN G PNTN QFFITT L+GK+ +FG+++ S +++ IEN V Sbjct: 159 ------LSMANSG-PNTNGCQFFITTKKCEWLDGKNVVFGRIIDNDSLLLLKKIENVSVT 211 Query: 181 SDGV-PESDVRISDCG 195 P+ + + +CG Sbjct: 212 PYIYKPKIPINVVECG 227 >5YZG-2 nrPDB Length = 646 Score = 97.8 bits (242), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 69/189 (36%), Positives = 88/189 (46%), Gaps = 42/189 (22%) Query: 10 DISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNF 69 D +I +G I KLF + PKT ENF C Y G+ FHR++K F Sbjct: 492 DSAIIHTSMGDIHTKLFPVECPKTVENF---CVHSRNG--------YYNGHTFHRIIKGF 540 Query: 70 MIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVE--PF 127 MIQ GD + G GG SI+ G FEDE P+ Sbjct: 541 MIQTGD----------PTGTGMGGESIWG--------------GEFEDEFHSTLRHDRPY 576 Query: 128 TLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPES 187 TL MAN GS NTN SQFFIT P L+ KH++FG+V G VV+ I N +V+ P++ Sbjct: 577 TLSMANAGS-NTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVN----PKT 631 Query: 188 DVRISDCGV 196 D D + Sbjct: 632 DKPYEDVSI 640 >3K2C-A nrPDB Length = 193 Score = 96.7 bits (239), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 71/191 (37%), Positives = 98/191 (51%), Gaps = 32/191 (16%) Query: 7 VYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVV 66 VY D+ +++ +GRIV KL + PKT +NF LC + P + YKG+ FHR++ Sbjct: 30 VYFDVYANEESLGRIVMKLEDDIVPKTAKNFRTLC----ERPKGE----GYKGSTFHRII 81 Query: 67 KNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEP 126 FM+Q GD ++ G GG SIY +K F NFE ++ E + Sbjct: 82 PGFMVQGGDY---------TAHNGTGGRSIYGEK---------FPDENFELKHTKEGI-- 121 Query: 127 FTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPE 186 L MAN G+ +TN SQFFIT L+ KH +FG+VV G VV I +S V + Sbjct: 122 --LSMANCGA-HTNGSQFFITLGKTQWLDEKHVVFGEVVEGMDVVHKIAKYGSESGQVKK 178 Query: 187 S-DVRISDCGV 196 + I DCGV Sbjct: 179 GYRIEIRDCGV 189 >1XWN-A nrPDB Length = 174 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/192 (35%), Positives = 94/192 (48%), Gaps = 45/192 (23%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 Q P VYL+ S+ G IV +L+ + APKT +NF +L + Y G F Sbjct: 10 QPPNVYLETSM-----GIIVLELYWKHAPKTCKNFAELA-----------RRGYYNGTKF 53 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDE---N 119 HR++K+FMIQ GD + G+GG SIY + FEDE + Sbjct: 54 HRIIKDFMIQGGD----------PTGTGRGGASIYGKQ--------------FEDELHPD 89 Query: 120 LGEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 L +F L MAN G P+TN SQFF+T L+GKH+IFG+V G +V + Sbjct: 90 L-KFTGAGILAMANAG-PDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVET 147 Query: 180 DSDGVPESDVRI 191 +S P DV+I Sbjct: 148 NSQDRPVDDVKI 159 >2K7N-A nrPDB Length = 203 Score = 96.3 bits (238), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/192 (35%), Positives = 94/192 (48%), Gaps = 45/192 (23%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 Q P VYL+ S+ G IV +L+ + APKT +NF +L + Y G F Sbjct: 10 QPPNVYLETSM-----GIIVLELYWKHAPKTCKNFAELA-----------RRGYYNGTKF 53 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDE---N 119 HR++K+FMIQ GD + G+GG SIY + FEDE + Sbjct: 54 HRIIKDFMIQGGD----------PTGTGRGGASIYGKQ--------------FEDELHPD 89 Query: 120 LGEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 L +F L MAN G P+TN SQFF+T L+GKH+IFG+V G +V + Sbjct: 90 L-KFTGAGILAMANAG-PDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVET 147 Query: 180 DSDGVPESDVRI 191 +S P DV+I Sbjct: 148 NSQDRPVDDVKI 159 >2A2N-A nrPDB Length = 176 Score = 95.5 bits (236), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 70/196 (35%), Positives = 91/196 (46%), Gaps = 42/196 (21%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 + P D +I +G I KLF + PKT ENF C + Y G+ F Sbjct: 15 EGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENF---CV--------HSRNGYYNGHTF 63 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HR++K FMIQ GD + G GG SI+ G FEDE Sbjct: 64 HRIIKGFMIQTGD----------PTGTGMGGESIWG--------------GEFEDEFHST 99 Query: 123 FVE--PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 P+TL MAN GS NTN SQFFIT P L+ KH++FG+V G VV+ I N +V+ Sbjct: 100 LRHDRPYTLSMANAGS-NTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVN 158 Query: 181 SDGVPESDVRISDCGV 196 P++D D + Sbjct: 159 ----PKTDKPYEDVSI 170 >2FU0-A nrPDB Length = 160 Score = 89.0 bits (219), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 60/155 (38%), Positives = 78/155 (50%), Gaps = 23/155 (14%) Query: 37 FYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSI 96 FYK C V++ Y FHRV+K+FM+Q GD S G GG SI Sbjct: 22 FYKECKKTVQNFSVHSINGYYNNCIFHRVIKHFMVQTGD----------PSGDGTGGESI 71 Query: 97 YADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNG 156 + ++ E DE F + N +PF + MAN G PNTN SQFFITT P L+ Sbjct: 72 WGNEFE----DEFFDHLNHS--------KPFMVSMANCG-PNTNGSQFFITTVPCPWLDF 118 Query: 157 KHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRI 191 KH++FG+V G +V IE R D P D++I Sbjct: 119 KHTVFGKVTQGSKIVLDIEKVRTDKRDKPLEDIKI 153 >2OK3-A nrPDB Length = 161 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 65/177 (36%), Positives = 87/177 (49%), Gaps = 35/177 (19%) Query: 18 IGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIV 77 +G I ++F E+ PKT ENF LCA + Y G FHR +K FM+Q GD Sbjct: 9 VGDIKIEVFCERTPKTCENFLALCASNY-----------YNGCIFHRNIKGFMVQTGD-- 55 Query: 78 FGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSP 137 + G+GG SI+ K E DE Y + N+ V MAN G P Sbjct: 56 --------PTGTGRGGNSIWGKKFE----DE---YSEYLKHNVRGVVS-----MANNG-P 94 Query: 138 NTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV-PESDVRISD 193 NTN SQFFIT PHL+ K+++FG+V+ G + +E V+ P +DV I D Sbjct: 95 NTNGSQFFITYGKQPHLDMKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKD 151 >2B71-A nrPDB Length = 196 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 60/176 (34%), Positives = 81/176 (46%), Gaps = 38/176 (21%) Query: 18 IGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIV 77 +G +L+ +PKT NFY LC + Y FHRV+ NF+IQ GD Sbjct: 47 LGDFEVELYWYHSPKTCLNFYTLC-----------EMGFYDNTIFHRVIPNFVIQGGD-- 93 Query: 78 FGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF--VEPFTLGMANLG 135 + GKGG SIY + FEDE E L M+N G Sbjct: 94 --------PTGTGKGGKSIYGEY--------------FEDEINKELKHTGAGILSMSNNG 131 Query: 136 SPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRI 191 PNTN+SQFFIT PHL+GKH+IF +V + + I + + + P D++I Sbjct: 132 -PNTNSSQFFITLAPLPHLDGKHTIFARVSKNMTCIENIASVQTTATNKPIFDLKI 186 >2QER-A nrPDB Length = 185 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 59/178 (33%), Positives = 83/178 (46%), Gaps = 36/178 (20%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G + +LF + PK +NF L A YK FH+ +K F+IQ GD Sbjct: 26 GDLKFELFCSQCPKACKNFLALSASGY-----------YKNTIFHKNIKGFIIQGGD--- 71 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGS-- 136 + GKGG SIY DDE + ++ + L MA+ G+ Sbjct: 72 -------PTGTGKGGESIYGRY----FDDEIYPELKYDRRGI--------LSMASKGASK 112 Query: 137 -PNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISD 193 PNTN SQFFIT + P LNG++ IFG+++ G + T+ENC D P ++ I D Sbjct: 113 KPNTNGSQFFITYSSLPQLNGEYVIFGKLIDGFETLNTLENCPSDKSHKPIDEIIIKD 170 >1W74-A nrPDB Length = 191 Score = 78.2 bits (191), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 62/179 (34%), Positives = 75/179 (41%), Gaps = 32/179 (17%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAG----DVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 G I LF APKT NF L G ++ Y G FHRV++ FMIQ G Sbjct: 33 GDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFMIQGG 92 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 D K DE F E +F +P+ L MAN Sbjct: 93 DP-----------------TGTGRGGPGYKFADE------FHPEL--QFDKPYLLAMANA 127 Query: 135 GSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKS--VVRTIENCRVDSDGVPESDVRI 191 G P TN SQFFIT PHLN +H+IFG+V+ +S VV I D + P V I Sbjct: 128 G-PGTNGSQFFITVGKTPHLNRRHTIFGEVIDAESQRVVEAISKTATDGNDRPTDPVVI 185 >5Z56-z nrPDB Length = 472 Score = 70.9 bits (172), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 63/197 (31%), Positives = 85/197 (43%), Gaps = 38/197 (19%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 IQ+P + + K G I +L+ ++APK NF +LC + Y Y Sbjct: 6 IQEPPTNGKVLL-KTTAGDIDIELWSKEAPKACRNFIQLCL---------EAY--YDNTI 53 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVV F++Q GD + G GG SIY DE F L Sbjct: 54 FHRVVPGFIVQGGD----------PTGTGSGGESIYG----APFKDEFHSRLRFNRRGL- 98 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV--VRTIENCRV 179 + MAN GS + N SQFF T A LN KH+IFG+V G +V + + + Sbjct: 99 -------VAMANAGS-HDNGSQFFFTLGRADELNNKHTIFGKVT-GDTVYNMLRLSEVDI 149 Query: 180 DSDGVPESDVRISDCGV 196 D D P + +I C V Sbjct: 150 DDDERPHNPHKIKSCEV 166 >4R3E-A nrPDB Length = 180 Score = 67.0 bits (162), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 63/197 (31%), Positives = 85/197 (43%), Gaps = 38/197 (19%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 IQ+P + + K G I +L+ ++APK NF +LC + Y Y Sbjct: 8 IQEPPTNGKVLL-KTTAGDIDIELWSKEAPKACRNFIQLCL---------EAY--YDNTI 55 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVV F++Q GD + G GG SIY DE F L Sbjct: 56 FHRVVPGFIVQGGD----------PTGTGSGGESIYG----APFKDEFHSRLRFNRRGL- 100 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV--VRTIENCRV 179 + MAN GS + N SQFF T A LN KH+IFG+V G +V + + + Sbjct: 101 -------VAMANAGS-HDNGSQFFFTLGRADELNNKHTIFGKVT-GDTVYNMLRLSEVDI 151 Query: 180 DSDGVPESDVRISDCGV 196 D D P + +I C V Sbjct: 152 DDDERPHNPHKIKSCEV 168 >2HQ6-A nrPDB Length = 185 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 60/184 (32%), Positives = 79/184 (42%), Gaps = 37/184 (20%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 K G I +L+ ++APK NF +LC + Y Y FHRVV F++Q G Sbjct: 30 KTTAGDIDIELWSKEAPKACRNFIQLCL---------EAY--YDNTIFHRVVPGFIVQGG 78 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 D + G GG SIY DE F L + MAN Sbjct: 79 D----------PTGTGSGGESIYG----APFKDEFHSRLRFNRRGL--------VAMANA 116 Query: 135 GSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV--VRTIENCRVDSDGVPESDVRIS 192 GS + N SQFF T A LN KH+IFG+V G +V + + +D D P + +I Sbjct: 117 GS-HDNGSQFFFTLGRADELNNKHTIFGKVT-GDTVYNMLRLSEVDIDDDERPHNPHKIK 174 Query: 193 DCGV 196 C V Sbjct: 175 SCEV 178 >1ZKC-A nrPDB Length = 197 Score = 66.2 bits (160), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 65/199 (32%), Positives = 91/199 (45%), Gaps = 44/199 (22%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G + +L + PKT ENF +LC + Y Y G FHR ++NF+IQ Sbjct: 29 GDLNLELHCDLTPKTCENFIRLCK---------KHY--YDGTIFHRSIRNFVIQG----- 72 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDE---NLGEFVEPFTLGMANLG 135 D T ES+ F+DE NL L MAN G Sbjct: 73 -------------------GDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGI-LSMANSG 112 Query: 136 SPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCG 195 PN+N SQFFIT + +L+ KH+IFG+VV G V+ +EN V+SD P++D + Sbjct: 113 -PNSNRSQFFITFRSCAYLDKKHTIFGRVVGGFDVLTAMEN--VESD--PKTDRPKEEIR 167 Query: 196 VWEKTMGVPLYNASNDQIG 214 + T+ V Y ++ QI Sbjct: 168 IDATTVFVDPYEEADAQIA 186 >4R3F-A nrPDB Length = 204 Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 57/192 (29%), Positives = 87/192 (45%), Gaps = 37/192 (19%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G + +LF ++ P T NF L+ Y G FHR+V F+IQ GD Sbjct: 25 GDLKVELFAKQTPLTCRNF-----------LQHSLDGYYDGTIFHRLVPGFIIQGGD--- 70 Query: 79 GTQKDSSSSSVGKGGCSIY-----------ADKEEVKTDDESFCYGNFEDE--NLGEFVE 125 + G GG SIY ++ K + NF+DE + +F Sbjct: 71 -------PTGTGHGGESIYDGGAFSGDLDPWPMDQRKGHNAGPMGVNFKDEFHSRLKFNR 123 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV---VRTIENCRVDSD 182 LGMAN G+P+TN SQFF T A LN K+++FG+V G ++ ++ E ++ Sbjct: 124 RGLLGMANEGAPDTNGSQFFFTLGKAEELNNKNTLFGRVAAGDTIYNLMKWGEAELIEGT 183 Query: 183 GVPESDVRISDC 194 P+ V+I++ Sbjct: 184 ERPQYPVKITNI 195 >3BO7-A nrPDB Length = 201 Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 51/157 (32%), Positives = 77/157 (49%), Gaps = 22/157 (14%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G + +L + AP+ ++F +LCA VK + FHR ++NFMIQ G Sbjct: 16 GSLNIELHADMAPRACDSFLRLCA--VKY---------FDDTIFHRCIRNFMIQGGRAEL 64 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPN 138 ++ S V + SI +DE F++ + + + L MAN G + Sbjct: 65 --RQPSKKKEVQQSPRSISGFPGGAPFEDE------FDNRLVHQGIG--VLSMANDGK-H 113 Query: 139 TNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIE 175 +N S+FFIT + HLN KH+IFG+VV G V+R E Sbjct: 114 SNLSEFFITFKSCEHLNNKHTIFGRVVGGLDVLRQWE 150 >3T1U-A nrPDB Length = 163 Score = 60.8 bits (146), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 55/188 (29%), Positives = 80/188 (42%), Gaps = 54/188 (28%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYL---SYKGNGFHRVVKNFMIQAGD 75 G I KLF +KAP+T NF +QY+ Y G FHRV+ FMIQ G Sbjct: 9 GTITLKLFADKAPETAANF--------------EQYVKDGHYDGTIFHRVIDGFMIQGGG 54 Query: 76 IVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLG 135 G ++ S+ + + K E N G + +T+ MA Sbjct: 55 FEPGMKQKSTRAPI----------KNEA---------------NNGLSNKKYTIAMARTP 89 Query: 136 SPNTNNSQFFITT-------YAAPHLNG-KHSIFGQVVHGKSVVRTIENC----RVDSDG 183 P++ ++QFFI + AP +G +++FG+VV G VV I++ R Sbjct: 90 DPHSASAQFFINVKDNAFLDHTAPTAHGWGYAVFGEVVEGTDVVDRIKSVATGSRAGHGD 149 Query: 184 VPESDVRI 191 VP DV I Sbjct: 150 VPVDDVII 157 >2MVZ-A nrPDB Length = 148 Score = 57.8 bits (138), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 51/161 (31%), Positives = 69/161 (42%), Gaps = 37/161 (22%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G+I +LF +AP T NF KL ++ + Y G FHRV+ F+ Q Sbjct: 15 GKIEFELFPNEAPVTVANFEKLA---------NEGF--YNGLTFHRVIPGFVSQ------ 57 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPN 138 GGC T D + D N V + MA+ G + Sbjct: 58 -------------GGCP-----RGNGTGDAGYTIPCETDNNPHRHVTG-AMSMAHRGR-D 97 Query: 139 TNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 T + QFFI PHL+G H++FGQV G VVRT++N V Sbjct: 98 TGSCQFFIVHEPQPHLDGVHTVFGQVTSGMDVVRTMKNGDV 138 >5OMP-A nrPDB Length = 462 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%) Query: 232 DFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLK 291 D + LE A I+KE GT+ FK Y A +Y K ++++ + + + + F+ Sbjct: 265 DTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFL--- 321 Query: 292 MKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQ 351 + +LNL++ L Y A+ L +D+ K YRRG + L + A Sbjct: 322 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSA----NEKGLYRRGEAQLLMNEFESAKG 377 Query: 352 DYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 D+ E NP ++ +I + +E+ E+ R+ + F Sbjct: 378 DFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 418 >1KT1-A nrPDB Length = 457 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 40/161 (24%), Positives = 72/161 (44%), Gaps = 7/161 (4%) Query: 232 DFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLK 291 D + LE A I+KE GT+ FK Y A +Y K ++++ + + + + F+ Sbjct: 260 DTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKESKASESFL--- 316 Query: 292 MKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQ 351 + +LNL++ L Y A+ L +D+ K YRRG + L + A Sbjct: 317 LAAFLNLAMCYLKLREYTKAVECCDKALGLDSA----NEKGLYRRGEAQLLMNEFESAKG 372 Query: 352 DYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 D+ E NP ++ +I + +E+ E+ R+ + F Sbjct: 373 DFEKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMF 413 >3S6M-A nrPDB Length = 167 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 50/190 (26%), Positives = 76/190 (40%), Gaps = 48/190 (25%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G I +L KAPKT ENF + Y G FHRV+ FMIQ G Sbjct: 13 GVIKLELDEAKAPKTVENFLNYV-----------KKGHYDGTIFHRVINGFMIQGGGFEP 61 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPN 138 G ++ + + + + N G + +T+ MA P+ Sbjct: 62 GLKQKPTDAPIA-------------------------NEANNGLKNDTYTIAMARTNDPH 96 Query: 139 TNNSQFFITT-------YAAPHLNG-KHSIFGQVVHGKSVVRTIENCRVDSDG----VPE 186 + +QFFI +++P G +++FG+VV G+ +V I+ + S G VP Sbjct: 97 SATAQFFINVNDNEFLNHSSPTPQGWGYAVFGKVVEGQDIVDKIKAVKTGSKGFHQDVPN 156 Query: 187 SDVRISDCGV 196 DV I V Sbjct: 157 DDVVIEKAVV 166 >2NUL-A nrPDB Length = 164 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 55/192 (28%), Positives = 75/192 (39%), Gaps = 48/192 (25%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G IV K F +KAP+T +NF C + Y FHRV+ FMIQ G Sbjct: 9 GDIVIKTFDDKAPETVKNFLDYC-----------REGFYNNTIFHRVINGFMIQGGGFEP 57 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPN 138 G ++ A KE +K + N G TL MA +P+ Sbjct: 58 GMKQK--------------ATKEPIK-----------NEANNGLKNTRGTLAMARTQAPH 92 Query: 139 TNNSQFFITT-------YAAPHLNG-KHSIFGQVVHGKSVVRTIENCRVDSDG----VPE 186 + +QFFI ++ L G + +F +VV G VV I+ G VP+ Sbjct: 93 SATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPK 152 Query: 187 SDVRISDCGVWE 198 DV I V E Sbjct: 153 EDVIIESVTVSE 164 >1QZ2-A nrPDB Length = 336 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 7/156 (4%) Query: 237 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 296 LE + I+KE GT+ FK+ Y A +Y+K ++++ EY E E + L++ +L Sbjct: 144 LEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL-EY--ESSFSNEEAQKAQALRLASHL 200 Query: 297 NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFC 356 NL++ L+ + AI LE+D+ + K +RRG ++L + A D+ Sbjct: 201 NLAMCHLKLQAFSAAIESCNKALELDS----NNEKGLFRRGEAHLAVNDFELARADFQKV 256 Query: 357 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 + P+++ + ++ + I + +K + F Sbjct: 257 LQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMF 292 >2OSE-A nrPDB Length = 234 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 14/101 (13%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDV-------KSPLKDQQYL 55 ++P VY+DI ++ + IGR+ KLFR+ P ENF +L G K +++ Sbjct: 13 KNPRVYMDIVLNNEIIGRLQIKLFRDAFPAGVENFVQLTNGKTYRVNSNGTGKYKYNRHI 72 Query: 56 --SYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGC 94 +Y+G FH V+ N I +GDI +S+ SS G C Sbjct: 73 NRTYEGCKFHNVLHNNYIVSGDIY-----NSNGSSAGTVYC 108 >3BKP-A nrPDB Length = 232 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 46/161 (28%), Positives = 67/161 (41%), Gaps = 44/161 (27%) Query: 18 IGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIV 77 +G + +L+ + P NF +LC + Y Y FHRVVK+F++Q GD Sbjct: 30 LGDLDVELWARECPLACRNFVQLCL---------EGY--YVNTIFHRVVKDFIVQGGD-- 76 Query: 78 FGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLG-- 135 + G+GG D + D E+ F L +G+ANLG Sbjct: 77 --------PTGTGRGGADTTFDGKPF--DVETHPRLKFRYRGL--------VGVANLGRS 118 Query: 136 -----------SPNTNNSQFFITTYAAPHLNGKHSIFGQVV 165 S TN +QFFIT A LN +++FG+V Sbjct: 119 SKDAENDERGRSLGTNGNQFFITLARADVLNNAYTLFGKVT 159 >2IF4-A nrPDB Length = 338 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 68/133 (51%), Gaps = 7/133 (5%) Query: 239 AANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNL 298 AA+ K G LFK++ A +Y ++ Y+ + K +++ + +K +LN+ Sbjct: 178 AADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMA-LAVKNPCHLNI 236 Query: 299 SLVLFNLERYDDAIMYATYLL-EMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCK 357 + L L+RYD+AI + +L E + P KA +RRG + + ++D A D+ + Sbjct: 237 AACLIKLKRYDEAIGHCNIVLTEEEKNP-----KALFRRGKAKAELGQMDSARDDFRKAQ 291 Query: 358 EKNPDDEVIEQRI 370 + PDD+ I + + Sbjct: 292 KYAPDDKAIRREL 304 >5EX1-A nrPDB Length = 283 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 39/166 (23%), Positives = 67/166 (40%), Gaps = 22/166 (13%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G I+ +L E AP F + + +Y G F+RV+ F+ Q G + Sbjct: 47 GDILIELNPEFAPGHVARFQDMV-----------KARAYNGKEFYRVIDGFVAQGG--ID 93 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYG---------NFEDENLGEFVEPFTL 129 K + + AD+ ++ +D+ F F+ E P L Sbjct: 94 AEDKKWPPLEIEHEQPLLEADQIQLLDNDDLFAEKVGFLNGFPVGFDAEKKWLLHCPGML 153 Query: 130 GMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIE 175 MA PNT + F+IT A +L+ ++FG+V+ G V+ ++ Sbjct: 154 AMARDSDPNTGGTDFYITLDAQRYLDRNMTVFGRVISGMQYVQKLQ 199 >5EX2-A nrPDB Length = 271 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 39/174 (22%), Positives = 70/174 (40%), Gaps = 31/174 (17%) Query: 25 LFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVFGTQKDS 84 ++ E AP+ N V++ L Y G FHRV+ FM Q GDI ++ Sbjct: 35 VYIELAPEIAPNHVAQIRKVVRTGL-------YSGTKFHRVISGFMAQGGDIAATLGREP 87 Query: 85 SSSSVGKG----------GCSIYADKEEVKTDDESFCYG-----------NFEDENLGEF 123 +V ++ ++++ K+ F G N+ ++ E Sbjct: 88 DLEAVDGEFVFRRDPKSIVLTVINEEDQTKSQYTGFYNGFPIETRQDELANYSEDKRVES 147 Query: 124 VEPFTLG---MANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTI 174 P G MA PN+ QFF+ + L+ K+S +G+++ G V +++ Sbjct: 148 WMPHCAGVVSMARTNDPNSGKDQFFLMRDESRFLDRKYSSWGRMLEGLDVAKSL 201 >5JJT-A nrPDB Length = 479 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 4/69 (5%) Query: 295 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 + N + LE Y AI A+ +E+D+ +K YYRRG +YL + +AL+D+ Sbjct: 46 WANRAFAHTKLEEYGSAIQDASKAIEVDS----RYSKGYYRRGAAYLAMGKFKDALKDFQ 101 Query: 355 FCKEKNPDD 363 K +P+D Sbjct: 102 QVKRLSPND 110 >2Y4T-A nrPDB Length = 450 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 43/74 (58%), Gaps = 4/74 (5%) Query: 310 DAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQR 369 +AI + +L+M+ D A R +YL ++ DEA+QDY +E N +D+ I + Sbjct: 313 EAIRVCSEVLQMEP----DNVNALKDRAEAYLIEEMYDEAIQDYETAQEHNENDQQIREG 368 Query: 370 IEYVNRLIEENKEK 383 +E RL+++++++ Sbjct: 369 LEKAQRLLKQSQKR 382 >1A17-A nrPDB Length = 166 Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust. Identities = 38/145 (26%), Positives = 61/145 (42%), Gaps = 24/145 (16%) Query: 236 ALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIY 295 AL+ A +K FK KDY NA Y +++ +N IY Sbjct: 9 ALKRAEELKTQANDYFKAKDYENAIKFYSQAIE-------------------LNPSNAIY 49 Query: 296 L-NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 N SL E Y A+ AT +E+D + K YYRR S + + AL+DY Sbjct: 50 YGNRSLAYLRTECYGYALGDATRAIELD----KKYIKGYYRRAASNMALGKFRAALRDYE 105 Query: 355 FCKEKNPDDEVIEQRIEYVNRLIEE 379 + P D+ + + + N+++++ Sbjct: 106 TVVKVKPHDKDAKMKYQECNKIVKQ 130 >4JA9-A nrPDB Length = 488 Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 61/145 (42%), Gaps = 24/145 (16%) Query: 236 ALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIY 295 L+ A +K FK KDY NA Y +++ +N IY Sbjct: 13 TLKRAEELKTQANDYFKAKDYENAIKFYSQAIE-------------------LNPSNAIY 53 Query: 296 L-NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 N SL E Y A+ AT +E+D + K YYRR S + + AL+DY Sbjct: 54 YGNRSLAYLRTECYGYALGDATRAIELD----KKYIKGYYRRAASNMALGKFRAALRDYE 109 Query: 355 FCKEKNPDDEVIEQRIEYVNRLIEE 379 + P+D+ + + + ++++++ Sbjct: 110 TVVKVKPNDKDAKMKYQECSKIVKQ 134 >5MGX-E nrPDB Length = 290 Score = 35.8 bits (81), Expect = 0.033, Method: Compositional matrix adjust. Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 5/131 (3%) Query: 240 ANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLS 299 AN +E G +++ D+ A Y ++ I + D+ E Q + LK+K NL+ Sbjct: 131 ANRKRECGNAHYQRADFVLAANSYDLAIKAITSSA-KVDMTFEEEAQLLQLKVKCLNNLA 189 Query: 300 LVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEK 359 L+ Y A+ + +LE D KA +R+G ++ EA+ + Sbjct: 190 ASQLKLDHYRAALRSCSLVLEHQP----DNIKALFRKGKVLAQQGEYSEAIPILRAALKL 245 Query: 360 NPDDEVIEQRI 370 P ++ I + Sbjct: 246 EPSNKTIHAEL 256 >1VAI-A nrPDB Length = 166 Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust. Identities = 50/203 (24%), Positives = 69/203 (33%), Gaps = 50/203 (24%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 DP V L S G I +L ++KAP + +NF Y FH Sbjct: 4 DPHVLLTTSA-----GNIELELDKQKAPVSVQNFVDYVNSGF-----------YNNTTFH 47 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 123 RV+ FMIQ G E+++ + N D L Sbjct: 48 RVIPGFMIQGGGFT-----------------------EQMQQKKPNPPIKNEADNGLRNT 84 Query: 124 VEPFTLGMANLGSPNTNNSQFFITTYAAPHL-NGK----HSIFGQVVHGKSVVRTIENCR 178 T+ MA ++ SQFFI L +G+ +++FG+VV G V I Sbjct: 85 RG--TIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVP 142 Query: 179 VDSDG----VPESDVRISDCGVW 197 G VP V I V Sbjct: 143 THDVGPYQNVPSKPVVILSATVL 165 >4B4Y-A nrPDB Length = 154 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 21/39 (53%) Query: 166 HGKSVVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVP 204 H KS+ + I +C VD +GV + + ++S G VP Sbjct: 71 HAKSIGKVISDCLVDLNGVKKHEPKLSSLGAMHTKKKVP 109 >1W3B-A nrPDB Length = 388 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 294 IYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDY 353 + L LS + F R D + ++T ++ + + A+AY GN Y ++ +L EA++ Y Sbjct: 35 VLLLLSSIHFQCRRLDRSAHFSTLAIKQNPL----LAEAYSNLGNVYKERGQLQEAIEHY 90 Query: 354 IFCKEKNPD 362 PD Sbjct: 91 RHALRLKPD 99 >6FO1-G nrPDB Length = 665 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 22/38 (57%) Query: 326 NRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDD 363 NR KAY RRG + ++L+EA +DY E P++ Sbjct: 197 NRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNN 234 >4I80-A nrPDB Length = 550 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 5/64 (7%) Query: 302 LFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIF-----C 356 L +LERY A+ L E++ P R Y +G + K DE + Y++ C Sbjct: 270 LGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYRDEHIYPYMYLAGYHC 329 Query: 357 KEKN 360 + +N Sbjct: 330 RNRN 333 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5JHE-A nrPDB 535 e-152 1IHG-A nrPDB 454 e-128 4JJM-A nrPDB 251 5e-67 2MC9-A nrPDB 249 1e-66 4E1Q-A nrPDB 248 3e-66 4HY7-A nrPDB 247 5e-66 4JCP-A nrPDB 246 9e-66 2HQJ-A nrPDB 246 1e-65 2POY-A nrPDB 241 5e-64 5YB9-A nrPDB 240 9e-64 2WFI-A nrPDB 237 7e-63 1E8K-A nrPDB 237 8e-63 6HMZ-X nrPDB 235 3e-62 2HE9-A nrPDB 234 5e-62 5O9Z-M nrPDB 234 5e-62 1C5F-A nrPDB 233 9e-62 1QNH-A nrPDB 230 7e-61 3R49-A nrPDB 230 1e-60 3RDD-A nrPDB 225 4e-59 2HAQ-A nrPDB 223 1e-58 5TA2-A nrPDB 222 2e-58 5YZG-3 nrPDB 222 3e-58 2CMT-A nrPDB 221 3e-58 1XQ7-A nrPDB 221 4e-58 2CFE-A nrPDB 220 7e-58 5MQF-o nrPDB 220 9e-58 3UCH-A nrPDB 220 1e-57 1IST-A nrPDB 218 3e-57 4EYV-A nrPDB 218 3e-57 2RMC-A nrPDB 216 2e-56 3ICH-A nrPDB 215 3e-56 2ESL-A nrPDB 214 6e-56 3PMP-A nrPDB 211 4e-55 1H0P-A nrPDB 208 2e-54 4I9Y-A nrPDB 205 4e-53 1Z81-A nrPDB 203 1e-52 3K2C-A nrPDB 202 3e-52 5OMP-A nrPDB 196 9e-51 6HIX-BQ nrPDB 196 1e-50 2A2N-A nrPDB 196 2e-50 1KT1-A nrPDB 195 3e-50 1QZ2-A nrPDB 195 3e-50 5YZG-2 nrPDB 194 6e-50 6HIX-BZ nrPDB 192 2e-49 3JB9-d nrPDB 191 5e-49 1XWN-A nrPDB 185 3e-47 2K7N-A nrPDB 184 4e-47 2C3B-A nrPDB 183 1e-46 2OK3-A nrPDB 178 3e-45 2FU0-A nrPDB 176 2e-44 1W74-A nrPDB 168 5e-42 1ZKC-A nrPDB 167 9e-42 4R3F-A nrPDB 164 4e-41 2B71-A nrPDB 164 5e-41 2QER-A nrPDB 164 8e-41 4R3E-A nrPDB 163 1e-40 2HQ6-A nrPDB 161 5e-40 2IF4-A nrPDB 161 6e-40 5Z56-z nrPDB 154 5e-38 3BO7-A nrPDB 151 7e-37 5EX1-A nrPDB 144 5e-35 2NUL-A nrPDB 142 2e-34 3T1U-A nrPDB 139 2e-33 2MVZ-A nrPDB 136 2e-32 3S6M-A nrPDB 135 3e-32 5EX2-A nrPDB 125 3e-29 3BKP-A nrPDB 121 7e-28 2OSE-A nrPDB 117 7e-27 5JJT-A nrPDB 102 2e-22 Sequences not found previously or not previously below threshold: 1VAI-A nrPDB 121 6e-28 5MGX-E nrPDB 89 3e-18 4JA9-A nrPDB 85 4e-17 1A17-A nrPDB 80 2e-15 6FO1-G nrPDB 78 7e-15 4I2W-A nrPDB 77 1e-14 2Y4T-A nrPDB 61 7e-10 3RFY-A nrPDB 58 5e-09 2C2L-A nrPDB 58 8e-09 2GW1-A nrPDB 51 7e-07 6B85-J nrPDB 49 3e-06 4CGU-A nrPDB 41 0.001 1W3B-A nrPDB 41 0.001 5IWY-A nrPDB 39 0.003 5KHR-J nrPDB 38 0.007 4I9E-A nrPDB 38 0.008 5WQL-B nrPDB 38 0.009 4I1A-A nrPDB 37 0.015 5JZ6-A nrPDB 37 0.016 4UZY-A nrPDB 37 0.020 6AF0-A nrPDB 36 0.039 4JHR-A nrPDB 36 0.039 5AEM-A nrPDB 35 0.048 5G04-F nrPDB 35 0.077 5G04-X nrPDB 34 0.13 5CTR-A nrPDB 33 0.21 5CTQ-A nrPDB 33 0.21 5LK3-A nrPDB 33 0.24 5OJ8-A nrPDB 32 0.34 5DSE-A nrPDB 32 0.38 5GM6-b nrPDB 32 0.39 1HH8-A nrPDB 32 0.42 3NF1-A nrPDB 32 0.50 6AHD-N nrPDB 32 0.57 3J98-H nrPDB 32 0.59 6FUZ-A nrPDB 31 0.73 6C95-A nrPDB 31 0.90 2VL7-A nrPDB 31 1.4 2DE0-X nrPDB 30 1.8 2YXX-A nrPDB 30 2.1 1W55-A nrPDB 30 2.4 6EQI-C nrPDB 29 2.7 3NUM-A nrPDB 29 3.1 3J8B-L nrPDB 29 3.2 5A5T-L nrPDB 29 3.3 5OJF-A nrPDB 29 4.4 3ZFW-A nrPDB 29 5.4 1F7U-A nrPDB 28 6.5 >5JHE-A nrPDB Length = 397 Score = 535 bits (1377), Expect = e-152, Method: Composition-based stats. Identities = 393/393 (100%), Positives = 393/393 (100%) Query: 1 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN Sbjct: 5 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 64 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL Sbjct: 65 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 124 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD Sbjct: 125 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 184 Query: 181 SDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAA 240 SDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAA Sbjct: 185 SDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAA 244 Query: 241 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL 300 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL Sbjct: 245 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL 304 Query: 301 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN 360 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN Sbjct: 305 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN 364 Query: 361 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS 393 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS Sbjct: 365 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS 397 >1IHG-A nrPDB Length = 370 Score = 454 bits (1169), Expect = e-128, Method: Composition-based stats. Identities = 127/393 (32%), Positives = 185/393 (47%), Gaps = 38/393 (9%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 +P V+ D+ I + +GRIV +LF + PKT ENF LC G+ + L +KG F Sbjct: 14 SNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGPTTGKPLHFKGCPF 73 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG- 121 HR++K FMIQ GD S+ G GG SIY +K FEDEN Sbjct: 74 HRIIKKFMIQGGDF---------SNQNGTGGESIYGEK--------------FEDENFHY 110 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 + + L MAN GS NTN SQFFITT PHL+GKH +FGQV+ G V + +EN V Sbjct: 111 KHDKEGLLSMANAGS-NTNGSQFFITTVPTPHLDGKHVVFGQVIKGMGVAKILENVEVKG 169 Query: 182 DGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDD-DTHFGDDDFGKALEAA 240 P I++CG ++ ++ GD + ++P+D D D D K L + Sbjct: 170 -EKPAKLCVIAECGELKEGDDWGIFPKDGS---GDSHPDFPEDADVDLKDVD--KILLIS 223 Query: 241 NIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSL 300 +K G FK +++ A KY K L Y+ + +Q + L LN+ Sbjct: 224 EDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVAL--SCVLNIGA 281 Query: 301 VLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN 360 + + A+ LE+D KA YRR + K D+AL D +E Sbjct: 282 CKLKMSDWQGAVDSCLEALEID----PSNTKALYRRAQGWQGLKEYDQALADLKKAQEIA 337 Query: 361 PDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS 393 P+D+ I+ + V + I+ K+K + +K F+ Sbjct: 338 PEDKAIQAELLKVKQKIKAQKDKEKAAYAKMFA 370 >4JJM-A nrPDB Length = 175 Score = 251 bits (640), Expect = 5e-67, Method: Composition-based stats. Identities = 80/197 (40%), Positives = 100/197 (50%), Gaps = 27/197 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+++ +P GRIV +LF + P+T ENF LC G+ K K + L YKG+ Sbjct: 4 MPNPKVFFDMTVGGQPAGRIVMELFADVTPRTAENFRALCTGE-KGIGKSGKPLHYKGSS 62 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL- 120 FHRV+ FM Q GD G G GG SIY K F DEN Sbjct: 63 FHRVIPGFMCQGGDFTAGN---------GTGGESIYGSK--------------FADENFV 99 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G P TN SQFF+ T L+GKH +FGQVV G VV+ IE Sbjct: 100 KKHTGPGILSMANAG-PGTNGSQFFVCTAKTEWLDGKHVVFGQVVEGMDVVKAIEKVG-S 157 Query: 181 SDGVPESDVRISDCGVW 197 S G V I+DCG Sbjct: 158 SSGRTNKPVVIADCGQL 174 >2MC9-A nrPDB Length = 178 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 80/197 (40%), Positives = 99/197 (50%), Gaps = 27/197 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+S+ +P GRIV +LF + P+T ENF LC G+ K + + L YK + Sbjct: 7 MPNPRVFFDMSVGGQPAGRIVMELFADTTPRTAENFRALCTGE-KGTGRSGKPLHYKDSS 65 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL- 120 FHRV+ FM Q GD G G GG SIY K F DEN Sbjct: 66 FHRVIPGFMCQGGDFTAGN---------GTGGESIYGAK--------------FADENFI 102 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFFI T L+GKH +FGQVV G VV+ IE Sbjct: 103 KKHTGPGILSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGQVVEGMDVVKAIEKVG-S 160 Query: 181 SDGVPESDVRISDCGVW 197 S G V + DCG Sbjct: 161 SSGRTAKKVVVEDCGQL 177 >4E1Q-A nrPDB Length = 207 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 78/197 (39%), Positives = 102/197 (51%), Gaps = 27/197 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+++ P GRIV +L+++ P+T ENF LC G+ K K + L YKG+ Sbjct: 37 MANPRVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGE-KGVGKSGKPLHYKGSA 95 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL- 120 FHRV+ +FM Q GD G G GG SIY +K F DE Sbjct: 96 FHRVIPDFMCQGGDFTRGN---------GTGGESIYGEK--------------FADEKFV 132 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + +P L MAN G PNTN SQFFI T L+GKH +FG+VV G VV+ IE Sbjct: 133 HKHTKPGILSMANAG-PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVG-S 190 Query: 181 SDGVPESDVRISDCGVW 197 G V I+DCG Sbjct: 191 RSGTCSKQVVIADCGQL 207 >4HY7-A nrPDB Length = 171 Score = 247 bits (631), Expect = 5e-66, Method: Composition-based stats. Identities = 78/197 (39%), Positives = 102/197 (51%), Gaps = 27/197 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ D+++ P GRIV +L+++ P+T ENF LC G+ K K + L YKG+ Sbjct: 1 MANPRVFFDMTVGGAPAGRIVMELYKDAVPRTVENFRALCTGE-KGVGKSGKPLHYKGSA 59 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL- 120 FHRV+ +FM Q GD G G GG SIY +K F DE Sbjct: 60 FHRVIPDFMCQGGDFTRGN---------GTGGESIYGEK--------------FADEKFV 96 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + +P L MAN G PNTN SQFFI T L+GKH +FG+VV G VV+ IE Sbjct: 97 HKHTKPGILSMANAG-PNTNGSQFFICTVPCNWLDGKHVVFGEVVEGMDVVKNIEKVG-S 154 Query: 181 SDGVPESDVRISDCGVW 197 G V I+DCG Sbjct: 155 RSGTCSKQVVIADCGQL 171 >4JCP-A nrPDB Length = 175 Score = 246 bits (629), Expect = 9e-66, Method: Composition-based stats. Identities = 81/197 (41%), Positives = 105/197 (53%), Gaps = 27/197 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + P V+ DI+I GRIV +LF + PKT ENF LC G+ + + + L YKG+ Sbjct: 5 MSRPKVFFDITIGGSNAGRIVMELFADIVPKTAENFRCLCTGE-RGMGRSGKKLHYKGSK 63 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ NFM+Q GD G G GG SIY +K F DEN Sbjct: 64 FHRVIPNFMLQGGDFTRGN---------GTGGESIYGEK--------------FPDENFQ 100 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFFI T L+GKH +FG+VV G +VV+ +E+ + Sbjct: 101 EKHTGPGVLSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGRVVEGMNVVKAVES-KGS 158 Query: 181 SDGVPESDVRISDCGVW 197 G +D+ ISDCG Sbjct: 159 QSGRTSADIVISDCGQL 175 >2HQJ-A nrPDB Length = 183 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 84/197 (42%), Positives = 103/197 (52%), Gaps = 22/197 (11%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ DISID K GRIV +L+ + PKT ENF LC G+ K + + L YK + Sbjct: 5 MTNPKVFFDISIDNKAAGRIVMELYADTVPKTAENFRALCTGE-KGKGRSGKPLHYKSSV 63 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRV+ NFMIQ GD G G GG SIY DESF G Sbjct: 64 FHRVIPNFMIQGGDFTRGN---------GTGGESIYG----TTFRDESFSG------KAG 104 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 L MAN G PNTN SQFFI T A P L+GKH +FG+V+ G VV+ +E S Sbjct: 105 RHTGLGCLSMANAG-PNTNGSQFFICTAATPWLDGKHVVFGRVIDGLDVVKKVERLG-SS 162 Query: 182 DGVPESDVRISDCGVWE 198 G S + +SDCG Sbjct: 163 SGKTRSRIVVSDCGEVA 179 >2POY-A nrPDB Length = 186 Score = 241 bits (614), Expect = 5e-64, Method: Composition-based stats. Identities = 85/194 (43%), Positives = 104/194 (53%), Gaps = 27/194 (13%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P+VY DISI + P GRI +LF +K P T ENF LC G+ K + + L Y G+ FH Sbjct: 19 NPVVYFDISIGQTPAGRITMELFADKVPITAENFRALCTGE-KGMGQSGKPLCYTGSFFH 77 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-E 122 R++ FMIQ GD G G GG SIY K F DEN Sbjct: 78 RIIPQFMIQGGDFTRGD---------GTGGESIYGSK--------------FRDENFVYT 114 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 PF L MAN G PNTN SQFFITT P L+GKH +FG+V+ G VV++IE C + Sbjct: 115 HDAPFLLSMANAG-PNTNGSQFFITTVPCPWLDGKHVVFGKVLEGMEVVKSIEKCG-SQN 172 Query: 183 GVPESDVRISDCGV 196 G P V I+ GV Sbjct: 173 GKPTKSVCITASGV 186 >5YB9-A nrPDB Length = 175 Score = 240 bits (612), Expect = 9e-64, Method: Composition-based stats. Identities = 83/199 (41%), Positives = 107/199 (53%), Gaps = 27/199 (13%) Query: 1 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 M++ P + DISI +G+IV +LF + PKT ENF LC G+ K K LSYKG Sbjct: 3 MLKRPKTFFDISIRGDKVGKIVFELFNDIVPKTAENFRALCTGE-KGIGKSGMPLSYKGT 61 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 FHR++ FMIQ GD G GG SIY K F+DEN Sbjct: 62 MFHRIIPQFMIQGGDFTR---------FNGTGGESIYGMK--------------FDDENF 98 Query: 121 G-EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 + +P L MAN G PNTN SQFFITT P L+G H +FGQV+ G +V+ IE+C Sbjct: 99 KVKHDKPGLLSMANAG-PNTNGSQFFITTVETPWLDGHHCVFGQVIEGMDIVKQIESCGT 157 Query: 180 DSDGVPESDVRISDCGVWE 198 +S G P + ++DCG + Sbjct: 158 ES-GRPRAMCMVTDCGEMK 175 >2WFI-A nrPDB Length = 179 Score = 237 bits (604), Expect = 7e-63, Method: Composition-based stats. Identities = 85/197 (43%), Positives = 111/197 (56%), Gaps = 25/197 (12%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 +Q P + DI+I+ +P GR+V +LF + PKT ENF LC G+ + Q+ L YK Sbjct: 7 VQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCL 66 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVVK+FM+Q GD S G+GG SIY G FEDE+ Sbjct: 67 FHRVVKDFMVQGGDF---------SEGNGRGGESIYG--------------GFFEDESFA 103 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + + F L MAN G +TN SQFFITT PHL+G H +FGQV+ G+ VVR IEN + D Sbjct: 104 VKHNKEFLLSMANRGK-DTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTD 162 Query: 181 SDGVPESDVRISDCGVW 197 + P ++VRI CG Sbjct: 163 AASKPFAEVRILSCGEL 179 >1E8K-A nrPDB Length = 173 Score = 237 bits (604), Expect = 8e-63, Method: Composition-based stats. Identities = 79/198 (39%), Positives = 102/198 (51%), Gaps = 27/198 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + V+ DI+I K GRIV +L+ + PKT NF LC G+ K + L +KG+ Sbjct: 1 MSRSKVFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGE-NGIGKSGKPLHFKGSK 59 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHR++ NFMIQ GD G G GG SIY +K F DEN Sbjct: 60 FHRIIPNFMIQGGDFTRGN---------GTGGESIYGEK--------------FPDENFK 96 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFF+ T L+GKH +FG+VV G VV+ +E+ Sbjct: 97 EKHTGPGVLSMANAG-PNTNGSQFFLCTVKTEWLDGKHVVFGRVVEGLDVVKAVESNGSQ 155 Query: 181 SDGVPESDVRISDCGVWE 198 S G P D I+DCG + Sbjct: 156 S-GKPVKDCMIADCGQLK 172 >6HMZ-X nrPDB Length = 180 Score = 235 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 78/198 (39%), Positives = 102/198 (51%), Gaps = 27/198 (13%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ DI I K GR+V +LF + P+T +NF LC G+ K + + L YKG+ Sbjct: 1 MANPKVFFDILIGKMKAGRVVMELFADVTPRTADNFRALCTGE-KGIGQAGKALHYKGSA 59 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHR++ FM Q GD G G GG SIY K F+DEN Sbjct: 60 FHRIIPGFMCQGGDFTRGN---------GTGGESIYGAK--------------FQDENFK 96 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFFI T L+GKH +FG+VV G +VV+ +E + Sbjct: 97 LKHTGPGILSMANSG-PNTNGSQFFICTDKTAWLDGKHVVFGKVVDGYNVVKAMEKVGSE 155 Query: 181 SDGVPESDVRISDCGVWE 198 GV V I DCG + Sbjct: 156 -RGVTSEPVVIEDCGEIK 172 >2HE9-A nrPDB Length = 192 Score = 234 bits (597), Expect = 5e-62, Method: Composition-based stats. Identities = 86/197 (43%), Positives = 110/197 (55%), Gaps = 25/197 (12%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 P + DI I+++P+GRI+ +LF + PKT +NF LC+G+ + L YKG+ FH Sbjct: 19 SPQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFH 78 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL-GE 122 RVVKNFMIQ GD S GKGG SIY G F+DEN + Sbjct: 79 RVVKNFMIQGGDF---------SEGNGKGGESIYG--------------GYFKDENFILK 115 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 F L MAN G +TN SQFFITT APHL+G H +FG V+ G V+ IEN + D+ Sbjct: 116 HDRAFLLSMANRGK-HTNGSQFFITTKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAA 174 Query: 183 GVPESDVRISDCGVWEK 199 P +DVR+ DCGV Sbjct: 175 SRPYADVRVIDCGVLAT 191 >5O9Z-M nrPDB Length = 177 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 77/195 (39%), Positives = 102/195 (52%), Gaps = 28/195 (14%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P+V+ D+SI + +GR+ +LF + PKT ENF + C G+ + KD + YKG+ FH Sbjct: 10 NPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFR---KDGVPIGYKGSTFH 66 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-E 122 RV+K+FMIQ GD V G G G SIY G F DEN Sbjct: 67 RVIKDFMIQGGDFVNGD---------GTGVASIY--------------RGPFADENFKLR 103 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P L MAN G P+TN QFFIT L+GKH +FG+++ G V+R IEN + Sbjct: 104 HSAPGLLSMANSG-PSTNGCQFFITCSKCDWLDGKHVVFGKIIDGLLVMRKIENVPTGPN 162 Query: 183 GVPESDVRISDCGVW 197 P+ V IS CG Sbjct: 163 NKPKLPVVISQCGEM 177 >1C5F-A nrPDB Length = 177 Score = 233 bits (595), Expect = 9e-62, Method: Composition-based stats. Identities = 85/193 (44%), Positives = 106/193 (54%), Gaps = 25/193 (12%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 V+LD++ID GRIV +L+ + AP+T NF LC G + + L YKG+ FHRV Sbjct: 8 RVFLDVTIDGNLAGRIVMELYNDIAPRTCNNFLMLCTGMAGTGKISGKPLHYKGSTFHRV 67 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 +KNFMIQ GD G G GG SIY G F+DE + Sbjct: 68 IKNFMIQGGDFTKGD---------GTGGESIYG--------------GMFDDEEFVMKHD 104 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 EPF + MAN G PNTN SQFFITT APHLN H +FG+VV G+ VV IE + +S Sbjct: 105 EPFVVSMANKG-PNTNGSQFFITTTPAPHLNNIHVVFGKVVSGQEVVTKIEYLKTNSKNR 163 Query: 185 PESDVRISDCGVW 197 P +DV I +CG Sbjct: 164 PLADVVILNCGEL 176 >1QNH-A nrPDB Length = 170 Score = 230 bits (587), Expect = 7e-61, Method: Composition-based stats. Identities = 78/196 (39%), Positives = 101/196 (51%), Gaps = 28/196 (14%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 + V+ DISID GRI+ +LF + P+T ENF LC G+ + L YK + F Sbjct: 2 KRSKVFFDISIDNSNAGRIIFELFSDITPRTCENFRALCTGEK--IGSRGKNLHYKNSIF 59 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG- 121 HR++ FM Q GDI G G GG SIY +F DEN Sbjct: 60 HRIIPQFMCQGGDITNGN---------GSGGESIYGR--------------SFTDENFNM 96 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 + +P L MAN G PNTN+SQF IT P L+GKH +FG+V+ G +VVR +E S Sbjct: 97 KHDQPGLLSMANAG-PNTNSSQFLITLVPCPWLDGKHVVFGKVIEGMNVVREMEKEGAKS 155 Query: 182 DGVPESDVRISDCGVW 197 G + V I+DCG W Sbjct: 156 -GYVKRSVVITDCGEW 170 >3R49-A nrPDB Length = 166 Score = 230 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 80/198 (40%), Positives = 102/198 (51%), Gaps = 34/198 (17%) Query: 1 MIQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 M +PLVYLD+ + KP+GR+V +L + PKT ENF LC G ++ YKG+ Sbjct: 1 MSGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTG--------EKGFGYKGS 52 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 FHRV+ +FM QAGD + G GG SIY + F DEN Sbjct: 53 TFHRVIPSFMCQAGDFT---------NHNGTGGKSIYGSR--------------FPDENF 89 Query: 121 G-EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 + V P L MAN G PNTN SQFFI T L+GKH +FG V+ G VV+ IE+ Sbjct: 90 TLKHVGPGVLSMANAG-PNTNGSQFFICTIKTDWLDGKHVVFGHVIEGMDVVKKIESFGS 148 Query: 180 DSDGVPESDVRISDCGVW 197 S G + I+DCG Sbjct: 149 KS-GRTSKKIVITDCGQL 165 >3RDD-A nrPDB Length = 184 Score = 225 bits (572), Expect = 4e-59, Method: Composition-based stats. Identities = 74/198 (37%), Positives = 100/198 (50%), Gaps = 34/198 (17%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P V+ DI++D +P+GR+ +LF +K PKT ENF L G ++ YKG+ Sbjct: 20 MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTG--------EKGFGYKGSC 71 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL- 120 FHR++ FM Q GD G GG SIY +K FEDEN Sbjct: 72 FHRIIPGFMCQGGDFTR---------HNGTGGKSIYGEK--------------FEDENFI 108 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G PNTN SQFFI T L+GKH +FG+V G ++V +E Sbjct: 109 LKHTGPGILSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFG-S 166 Query: 181 SDGVPESDVRISDCGVWE 198 +G + I+DCG E Sbjct: 167 RNGKTSKKITIADCGQLE 184 >2HAQ-A nrPDB Length = 172 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 79/192 (41%), Positives = 98/192 (51%), Gaps = 32/192 (16%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 VY D+ ID +P+GRI LF + AP TTENF +LC G + YK + FHRV Sbjct: 13 KVYFDVMIDSEPLGRITIGLFGKDAPLTTENFRQLCTG--------EHGFGYKDSIFHRV 64 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVE 125 ++NFMIQ GD + G GG SIY +K F DENL Sbjct: 65 IQNFMIQGGDFT---------NFDGTGGKSIYGEK--------------FADENLNVKHF 101 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVP 185 L MAN G PNTN SQFFITT P L+G+H +FG+V+ G VV IE + +S P Sbjct: 102 VGALSMANAG-PNTNGSQFFITTAPTPWLDGRHVVFGKVLDGMDVVLRIEKTKTNSHDRP 160 Query: 186 ESDVRISDCGVW 197 V+I G Sbjct: 161 VKPVKIVASGEL 172 >5TA2-A nrPDB Length = 163 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 73/195 (37%), Positives = 98/195 (50%), Gaps = 34/195 (17%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P V+ DI++D +P+GR+ +LF +K PKT ENF L G ++ YKG+ FH Sbjct: 2 NPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTG--------EKGFGYKGSCFH 53 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL-GE 122 R++ FM Q GD G GG SIY +K FEDEN + Sbjct: 54 RIIPGFMCQGGDFTR---------HNGTGGKSIYGEK--------------FEDENFILK 90 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P L MAN G PNTN SQFFI T L+GKH +FG+V G ++V +E + Sbjct: 91 HTGPGILSMANAG-PNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFG-SRN 148 Query: 183 GVPESDVRISDCGVW 197 G + I+DCG Sbjct: 149 GKTSKKITIADCGQL 163 >5YZG-3 nrPDB Length = 754 Score = 222 bits (565), Expect = 3e-58, Method: Composition-based stats. Identities = 85/197 (43%), Positives = 111/197 (56%), Gaps = 25/197 (12%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 +Q P + DI+I+ +P GR+V +LF + PKT ENF LC G+ + Q+ L YK Sbjct: 5 VQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCL 64 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVVK+FM+Q GD S G+GG SIY G FEDE+ Sbjct: 65 FHRVVKDFMVQGGDF---------SEGNGRGGESIYG--------------GFFEDESFA 101 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + + F L MAN G +TN SQFFITT PHL+G H +FGQV+ G+ VVR IEN + D Sbjct: 102 VKHNKEFLLSMANRGK-DTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTD 160 Query: 181 SDGVPESDVRISDCGVW 197 + P ++VRI CG Sbjct: 161 AASKPFAEVRILSCGEL 177 >2CMT-A nrPDB Length = 172 Score = 221 bits (564), Expect = 3e-58, Method: Composition-based stats. Identities = 75/194 (38%), Positives = 92/194 (47%), Gaps = 34/194 (17%) Query: 5 PLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHR 64 P V+ DI I GRIV +L + P+T ENF LC G ++ Y FHR Sbjct: 11 PRVFFDIRIGNGDAGRIVMELRSDIVPRTAENFRALCTG--------ERGFGYHNCCFHR 62 Query: 65 VVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EF 123 V+ FM Q GD V G G GG SIY K F+DEN Sbjct: 63 VIPQFMCQGGDFVKGD---------GTGGKSIYGRK--------------FDDENFQLRH 99 Query: 124 VEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDG 183 L MAN G PNTN SQFFI T L+GKH +FG+VV G++VV+ +E+ S G Sbjct: 100 EGFGVLSMANSG-PNTNGSQFFICTTKCDWLDGKHVVFGRVVDGQNVVKKMESVGSKS-G 157 Query: 184 VPESDVRISDCGVW 197 + V IS CG Sbjct: 158 KVKEPVIISRCGEL 171 >1XQ7-A nrPDB Length = 166 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 77/192 (40%), Positives = 104/192 (54%), Gaps = 32/192 (16%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 VY DI+I +P+GR+V LF PKT ENF +L +G + YKG+ FHRV Sbjct: 7 KVYFDITIGDEPVGRVVIGLFGNDVPKTVENFKQLASG--------ENGFGYKGSIFHRV 58 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVE 125 ++NFMIQ GD + G GG SIY + F+DENL Sbjct: 59 IRNFMIQGGDFT---------NFDGTGGKSIYGTR--------------FDDENLKIKHF 95 Query: 126 PFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVP 185 + MAN G PN+N SQFF+TT P L+G+H +FG+VV G VV+ +EN + + P Sbjct: 96 VGAVSMANAG-PNSNGSQFFVTTAPTPWLDGRHVVFGKVVEGMDVVKKVENTKTGLNDKP 154 Query: 186 ESDVRISDCGVW 197 + V+I+DCGV Sbjct: 155 KKAVKINDCGVL 166 >2CFE-A nrPDB Length = 162 Score = 220 bits (561), Expect = 7e-58, Method: Composition-based stats. Identities = 77/192 (40%), Positives = 98/192 (51%), Gaps = 34/192 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 V+ DI+ + P+G I KLF + PKT NF LC G ++ Y G+ FHRV Sbjct: 3 NVFFDITKNGAPLGTIKFKLFDDVVPKTAANFRALCTG--------EKGFGYAGSHFHRV 54 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 + +FM+Q GD G G GG SIY K F DEN + Sbjct: 55 IPDFMLQGGDFTAGN---------GTGGKSIYGAK--------------FADENFQLKHN 91 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 +P L MAN G PNTN SQFFITT L+GKH +FG+V+ G +VV+ IE S G Sbjct: 92 KPGLLSMANAG-PNTNGSQFFITTVVTSWLDGKHVVFGEVIDGMNVVKAIEAEGSGS-GK 149 Query: 185 PESDVRISDCGV 196 P S + I+ CGV Sbjct: 150 PRSRIEIAKCGV 161 >5MQF-o nrPDB Length = 301 Score = 220 bits (560), Expect = 9e-58, Method: Composition-based stats. Identities = 75/195 (38%), Positives = 94/195 (48%), Gaps = 34/195 (17%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 +P VY+DI I KP GRI L + P T ENF LC ++ +KG+ F Sbjct: 138 SNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCT--------HEKGFGFKGSSF 189 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL-G 121 HR++ FM Q GD + G GG SIY K F+DEN Sbjct: 190 HRIIPQFMCQGGDFT---------NHNGTGGKSIYGKK--------------FDDENFIL 226 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 + P L MAN G PNTN SQFF+T L+GKH +FG+V G V+R IE Sbjct: 227 KHTGPGLLSMANSG-PNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQG-SK 284 Query: 182 DGVPESDVRISDCGV 196 DG P+ V I+DCG Sbjct: 285 DGKPKQKVIIADCGE 299 >3UCH-A nrPDB Length = 174 Score = 220 bits (559), Expect = 1e-57, Method: Composition-based stats. Identities = 75/195 (38%), Positives = 94/195 (48%), Gaps = 34/195 (17%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 +P VY+DI I KP GRI L + P T ENF LC ++ +KG+ F Sbjct: 11 SNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCT--------HEKGFGFKGSSF 62 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL-G 121 HR++ FM Q GD + G GG SIY K F+DEN Sbjct: 63 HRIIPQFMCQGGDFT---------NHNGTGGKSIYGKK--------------FDDENFIL 99 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDS 181 + P L MAN G PNTN SQFF+T L+GKH +FG+V G V+R IE Sbjct: 100 KHTGPGLLSMANSG-PNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEAQG-SK 157 Query: 182 DGVPESDVRISDCGV 196 DG P+ V I+DCG Sbjct: 158 DGKPKQKVIIADCGE 172 >1IST-A nrPDB Length = 162 Score = 218 bits (556), Expect = 3e-57, Method: Composition-based stats. Identities = 74/193 (38%), Positives = 98/193 (50%), Gaps = 34/193 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 VY D+ D +PIGR+V KL+ + PKT ENF LC G ++ Y G+ FHRV Sbjct: 3 QVYFDVEADGQPIGRVVFKLYNDIVPKTAENFRALCTG--------EKGFGYAGSPFHRV 54 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFV- 124 + +FM+Q GD G G GG SIY G F DEN + Sbjct: 55 IPDFMLQGGDFTAGN---------GTGGKSIYG--------------GKFPDENFKKHHD 91 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 P L MAN G PNTN SQFFITT P L+GKH +FG+VV G +V+ +E+ G Sbjct: 92 RPGLLSMANAG-PNTNGSQFFITTVPCPWLDGKHVVFGEVVDGYDIVKKVESLG-SPSGA 149 Query: 185 PESDVRISDCGVW 197 ++ + ++ G Sbjct: 150 TKARIVVAKSGEL 162 >4EYV-A nrPDB Length = 167 Score = 218 bits (556), Expect = 3e-57, Method: Composition-based stats. Identities = 75/196 (38%), Positives = 99/196 (50%), Gaps = 34/196 (17%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + P VY DISID + GRIV KL+ + P T +NF +L K+ Y G+ Sbjct: 4 MSQPNVYFDISIDNQNAGRIVFKLYDDVVPLTAKNFRELA--------KNPAGQGYTGST 55 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHR++ FM+Q GD + G GG SIY +K F+DEN Sbjct: 56 FHRIIPQFMLQGGDFT---------NHNGTGGRSIYGNK--------------FKDENFQ 92 Query: 122 -EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + +P L MAN G P+TN SQFFITT L+GKH +FG+VV G VV+ +E Sbjct: 93 LKHTKPGLLSMANAG-PHTNGSQFFITTVVTSWLDGKHVVFGEVVEGMDVVKKVEAVGTQ 151 Query: 181 SDGVPESDVRISDCGV 196 S G P V+I+ G Sbjct: 152 S-GKPSKVVKITASGT 166 >2RMC-A nrPDB Length = 182 Score = 216 bits (549), Expect = 2e-56, Method: Composition-based stats. Identities = 75/200 (37%), Positives = 96/200 (48%), Gaps = 34/200 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 V+ D+ I K +GRIV LF PKT ENF L G ++ YKG+ FHRV Sbjct: 9 KVFFDVRIGDKDVGRIVIGLFGNVVPKTVENFVALATG--------EKGYGYKGSIFHRV 60 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 +K+FMIQ GD G GG SIY + F DEN + Sbjct: 61 IKDFMIQGGDFTARD---------GTGGMSIYGE--------------TFPDENFKLKHY 97 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 + MAN G P+TN SQFFIT L+GKH +FG+V+ G +VV +IE D Sbjct: 98 GIGWVSMANAG-PDTNGSQFFITLTKPTWLDGKHVVFGKVLDGMTVVHSIELQATDGHDR 156 Query: 185 PESDVRISDCG-VWEKTMGV 203 P +D I + G + KT V Sbjct: 157 PLTDCTIVNSGKIDVKTPFV 176 >3ICH-A nrPDB Length = 188 Score = 215 bits (547), Expect = 3e-56, Method: Composition-based stats. Identities = 75/194 (38%), Positives = 100/194 (51%), Gaps = 33/194 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 VY D+ I + +GR++ LF + PKT +NF L G ++ YK + FHRV Sbjct: 17 KVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATG--------EKGFGYKNSKFHRV 68 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 +K+FMIQ GD G G GG SIY ++ F DEN + Sbjct: 69 IKDFMIQGGDFTRGD---------GTGGKSIYGER--------------FPDENFKLKHY 105 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 P + MAN G +TN SQFFITT L+GKH +FG+V+ G VVR +E+ + DS Sbjct: 106 GPGWVSMANAGK-DTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDK 164 Query: 185 PESDVRISDCGVWE 198 P DV I+DCG E Sbjct: 165 PLKDVIIADCGKIE 178 >2ESL-A nrPDB Length = 190 Score = 214 bits (544), Expect = 6e-56, Method: Composition-based stats. Identities = 76/200 (38%), Positives = 99/200 (49%), Gaps = 34/200 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 V+ D+ I K +GRIV LF + PKT ENF L G ++ YKG+ FHRV Sbjct: 17 KVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATG--------EKGYGYKGSKFHRV 68 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 +K+FMIQ GDI G G GG SIY + F DEN + Sbjct: 69 IKDFMIQGGDITTGD---------GTGGVSIYGE--------------TFPDENFKLKHY 105 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 + MAN G P+TN SQFFIT L+GKH +FG+V+ G +VV +IE D Sbjct: 106 GIGWVSMANAG-PDTNGSQFFITLTKPTWLDGKHVVFGKVIDGMTVVHSIELQATDGHDR 164 Query: 185 PESDVRISDCG-VWEKTMGV 203 P ++ I + G + KT V Sbjct: 165 PLTNCSIINSGKIDVKTPFV 184 >3PMP-A nrPDB Length = 164 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 75/194 (38%), Positives = 100/194 (51%), Gaps = 34/194 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 V+ +ISI+ KP GRIV KL+ E PKT +NF +L G Q YK + FHRV Sbjct: 4 NVFFNISINDKPEGRIVFKLYDEAVPKTAKNFRELATG--------QHGFGYKDSIFHRV 55 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 + FM+Q GD G GG SIY +K F DEN + Sbjct: 56 IPQFMLQGGDFTR---------HNGTGGKSIYGEK--------------FADENFQVKHT 92 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 +P L MAN G+ NTN SQFFITT L+GKH +FG+V+ G +VR +E + + G Sbjct: 93 KPGLLSMANAGA-NTNGSQFFITTVPTSWLDGKHVVFGEVIEGLDIVRKVEG-KGSASGK 150 Query: 185 PESDVRISDCGVWE 198 + ++I+DCG Sbjct: 151 TNATIKITDCGTVA 164 >1H0P-A nrPDB Length = 182 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 75/191 (39%), Positives = 94/191 (49%), Gaps = 33/191 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 VY D+ I KPIGRIV LF + PKT NF +L K + Y G+ FHRV Sbjct: 8 RVYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELA--------KKPKGEGYPGSKFHRV 59 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 + +FMIQ GD G G GG SIY +K F DEN + Sbjct: 60 IADFMIQGGDFTRGD---------GTGGRSIYGEK--------------FADENFKLKHY 96 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 L MAN G+ +TN SQFFITT P L+G+H +FG+++ G VVR IE Sbjct: 97 GAGWLSMANAGA-DTNGSQFFITTVKTPWLDGRHVVFGKILEGMDVVRKIEQTEKLPGDR 155 Query: 185 PESDVRISDCG 195 P+ DV I+ G Sbjct: 156 PKQDVIIAASG 166 >4I9Y-A nrPDB Length = 167 Score = 205 bits (520), Expect = 4e-53, Method: Composition-based stats. Identities = 72/195 (36%), Positives = 96/195 (49%), Gaps = 34/195 (17%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 + +P+V+ D+ D +P+GRI +LF P+T ENF LC G ++ +K + Sbjct: 4 MTNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTG--------EKGFGFKNSI 55 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL- 120 FHRV+ +F+ Q GDI G GG SIY DK FEDEN Sbjct: 56 FHRVIPDFVCQGGDIT---------KHDGTGGQSIYGDK--------------FEDENFD 92 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 + P L MAN G NTNNSQF IT A HL+ KH +FG V G V+ IE+ Sbjct: 93 VKHTGPGLLSMANQGQ-NTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKIESFG-S 150 Query: 181 SDGVPESDVRISDCG 195 G + I++CG Sbjct: 151 PKGSVCRRITITECG 165 >1Z81-A nrPDB Length = 229 Score = 203 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 67/199 (33%), Positives = 102/199 (51%), Gaps = 31/199 (15%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 +P+V++DI++ +G+ +LF+ PKT+ENF + C G+ K + + YK F Sbjct: 58 SNPVVFMDINLGNNFLGKFKFELFQNIVPKTSENFRQFCTGEYK---VNNLPVGYKNTIF 114 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG- 121 HRV+K FMIQ GD + + G G SIY +K F+DEN Sbjct: 115 HRVIKEFMIQGGDFI---------NHNGSGSLSIYGEK--------------FDDENFDI 151 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKS--VVRTIENCRV 179 + + L MAN G PNTN QFFITT L+GK+ +FG+++ S +++ IEN V Sbjct: 152 KHDKEGLLSMANSG-PNTNGCQFFITTKKCEWLDGKNVVFGRIIDNDSLLLLKKIENVSV 210 Query: 180 DSD-GVPESDVRISDCGVW 197 P+ + + +CG Sbjct: 211 TPYIYKPKIPINVVECGEL 229 >3K2C-A nrPDB Length = 193 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 69/194 (35%), Positives = 93/194 (47%), Gaps = 34/194 (17%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRV 65 VY D+ +++ +GRIV KL + PKT +NF LC + + YKG+ FHR+ Sbjct: 29 NVYFDVYANEESLGRIVMKLEDDIVPKTAKNFRTLC--------ERPKGEGYKGSTFHRI 80 Query: 66 VKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG-EFV 124 + FM+Q GD G GG SIY +K F DEN + Sbjct: 81 IPGFMVQGGDYTA---------HNGTGGRSIYGEK--------------FPDENFELKHT 117 Query: 125 EPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGV 184 + L MAN G+ +TN SQFFIT L+ KH +FG+VV G VV I +S V Sbjct: 118 KEGILSMANCGA-HTNGSQFFITLGKTQWLDEKHVVFGEVVEGMDVVHKIAKYGSESGQV 176 Query: 185 PE-SDVRISDCGVW 197 + + I DCGV Sbjct: 177 KKGYRIEIRDCGVL 190 >5OMP-A nrPDB Length = 462 Score = 196 bits (499), Expect = 9e-51, Method: Composition-based stats. Identities = 40/163 (24%), Positives = 73/163 (44%), Gaps = 7/163 (4%) Query: 230 DDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFIN 289 + D + LE A I+KE GT+ FK Y A +Y K ++++ + + + + F+ Sbjct: 263 EMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFL- 321 Query: 290 LKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEA 349 + +LNL++ L Y A+ L +D+ K YRRG + L + A Sbjct: 322 --LAAFLNLAMCYLKLREYTKAVECCDKALGLDSA----NEKGLYRRGEAQLLMNEFESA 375 Query: 350 LQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 D+ E NP ++ +I + +E+ E+ R+ + F Sbjct: 376 KGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMF 418 >6HIX-BQ nrPDB Length = 231 Score = 196 bits (499), Expect = 1e-50, Method: Composition-based stats. Identities = 66/192 (34%), Positives = 95/192 (49%), Gaps = 24/192 (12%) Query: 4 DPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFH 63 +P+V++D++++ +GR+ +LF + PKTTENF LC G+ Q L YKG FH Sbjct: 28 NPVVFMDVTVEGDALGRVSVELFHDIVPKTTENFRSLCTGERG---YSQCPLFYKGIPFH 84 Query: 64 RVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEF 123 RV+ F++Q GDI+ G+G S++ DESF E Sbjct: 85 RVIPGFIVQGGDILLKD---------GRGNVSVFG----FPFPDESF-------EGKAGK 124 Query: 124 VEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDG 183 T+ MA+ +PN N SQFF HL+GK + GQV+ G VV + S G Sbjct: 125 HLRGTVAMAH-SAPNQNGSQFFFNLARNDHLDGKFVVCGQVIDGWEVVDRVAVLSGSSCG 183 Query: 184 VPESDVRISDCG 195 P S I++CG Sbjct: 184 TPVSRAWITECG 195 >2A2N-A nrPDB Length = 176 Score = 196 bits (497), Expect = 2e-50, Method: Composition-based stats. Identities = 67/195 (34%), Positives = 88/195 (45%), Gaps = 35/195 (17%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 + P D +I +G I KLF + PKT ENF + Y G+ F Sbjct: 15 EGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENF-----------CVHSRNGYYNGHTF 63 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HR++K FMIQ GD + G GG SI+ + E + Sbjct: 64 HRIIKGFMIQTGD----------PTGTGMGGESIWGGEFEDEFHSTL------------R 101 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P+TL MAN GS NTN SQFFIT P L+ KH++FG+V G VV+ I N +V+ Sbjct: 102 HDRPYTLSMANAGS-NTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPK 160 Query: 183 -GVPESDVRISDCGV 196 P DV I + V Sbjct: 161 TDKPYEDVSIINITV 175 >1KT1-A nrPDB Length = 457 Score = 195 bits (495), Expect = 3e-50, Method: Composition-based stats. Identities = 40/163 (24%), Positives = 73/163 (44%), Gaps = 7/163 (4%) Query: 230 DDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFIN 289 + D + LE A I+KE GT+ FK Y A +Y K ++++ + + + + F+ Sbjct: 258 EMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSEKESKASESFL- 316 Query: 290 LKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEA 349 + +LNL++ L Y A+ L +D+ K YRRG + L + A Sbjct: 317 --LAAFLNLAMCYLKLREYTKAVECCDKALGLDSA----NEKGLYRRGEAQLLMNEFESA 370 Query: 350 LQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 D+ E NP ++ +I + +E+ E+ R+ + F Sbjct: 371 KGDFEKVLEVNPQNKAARLQIFMCQKKAKEHNERDRRTYANMF 413 >1QZ2-A nrPDB Length = 336 Score = 195 bits (495), Expect = 3e-50, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 76/163 (46%), Gaps = 7/163 (4%) Query: 230 DDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFIN 289 + + + LE + I+KE GT+ FK+ Y A +Y+K ++++ E E + Sbjct: 137 EMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLE---YESSFSNEEAQKAQA 193 Query: 290 LKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEA 349 L++ +LNL++ L+ + AI LE+D+ + K +RRG ++L + A Sbjct: 194 LRLASHLNLAMCHLKLQAFSAAIESCNKALELDS----NNEKGLFRRGEAHLAVNDFELA 249 Query: 350 LQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 D+ + P+++ + ++ + I + +K + F Sbjct: 250 RADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMF 292 >5YZG-2 nrPDB Length = 646 Score = 194 bits (493), Expect = 6e-50, Method: Composition-based stats. Identities = 67/195 (34%), Positives = 88/195 (45%), Gaps = 35/195 (17%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 + P D +I +G I KLF + PKT ENF + Y G+ F Sbjct: 485 EGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENF-----------CVHSRNGYYNGHTF 533 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HR++K FMIQ GD + G GG SI+ + E + Sbjct: 534 HRIIKGFMIQTGD----------PTGTGMGGESIWGGEFEDEFHSTL------------R 571 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 P+TL MAN GS NTN SQFFIT P L+ KH++FG+V G VV+ I N +V+ Sbjct: 572 HDRPYTLSMANAGS-NTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPK 630 Query: 183 -GVPESDVRISDCGV 196 P DV I + V Sbjct: 631 TDKPYEDVSIINITV 645 >6HIX-BZ nrPDB Length = 190 Score = 192 bits (488), Expect = 2e-49, Method: Composition-based stats. Identities = 75/206 (36%), Positives = 94/206 (45%), Gaps = 34/206 (16%) Query: 6 LVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQ------------Q 53 ++DI+I K RIV KLF K P +NF +LC+G+V + + Sbjct: 6 RAFMDIAIGTKAPRRIVFKLFPRKCPSAVKNFIELCSGNVSTDTYESGNRDKLISESALP 65 Query: 54 YLSYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYG 113 L+YK + FHRV K ++IQ GDIV G G SIY Sbjct: 66 QLTYKNSTFHRVEKGYLIQGGDIVTGR---------GTEQLSIYGGTFSAP--------- 107 Query: 114 NFEDENLGEFVEPFTLGMANLGSPNTNNSQFFI-TTYAAPHLNGKHSIFGQVVHGKSVVR 172 E+ F +P +G A SPN + SQFFI T A HLNG FGQV G VV+ Sbjct: 108 --EEVRASVFDKPGLVGTA-SSSPNAHGSQFFILTAKEANHLNGTCICFGQVADGLDVVQ 164 Query: 173 TIENCRVDSDGVPESDVRISDCGVWE 198 IE +D G P V I DCGV E Sbjct: 165 EIEQVPIDPSGFPSLKVSIVDCGVLE 190 >3JB9-d nrPDB Length = 155 Score = 191 bits (484), Expect = 5e-49, Method: Composition-based stats. Identities = 67/178 (37%), Positives = 87/178 (48%), Gaps = 34/178 (19%) Query: 16 KPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGD 75 +G+I+ +L+ E APKT +NFY L + Y G FHRV+ +F+IQ GD Sbjct: 8 TSLGKILIELYTEHAPKTCQNFYTLA-----------KEGYYDGVIFHRVIPDFVIQGGD 56 Query: 76 IVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLG 135 + G+GG SIY DK DDE L MAN G Sbjct: 57 ----------PTGTGRGGTSIYGDK----FDDEIHSDL--------HHTGAGILSMANAG 94 Query: 136 SPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISD 193 PNTN+SQFFIT P L+GKH+IFG+VV G SV + + R DS P ++I Sbjct: 95 -PNTNSSQFFITLAPTPWLDGKHTIFGRVVSGLSVCKRMGLIRTDSSDRPIEPLKIIK 151 >1XWN-A nrPDB Length = 174 Score = 185 bits (469), Expect = 3e-47, Method: Composition-based stats. Identities = 65/191 (34%), Positives = 89/191 (46%), Gaps = 39/191 (20%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 Q P VYL+ +G IV +L+ + APKT +NF +L + Y G F Sbjct: 10 QPPNVYLE-----TSMGIIVLELYWKHAPKTCKNFAELA-----------RRGYYNGTKF 53 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HR++K+FMIQ GD + G+GG SIY + +DE F Sbjct: 54 HRIIKDFMIQGGD----------PTGTGRGGASIYGKQ----FEDELHPDLKF------- 92 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 L MAN G P+TN SQFF+T L+GKH+IFG+V G +V + +S Sbjct: 93 -TGAGILAMANAG-PDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQ 150 Query: 183 GVPESDVRISD 193 P DV+I Sbjct: 151 DRPVDDVKIIK 161 >2K7N-A nrPDB Length = 203 Score = 184 bits (468), Expect = 4e-47, Method: Composition-based stats. Identities = 65/191 (34%), Positives = 89/191 (46%), Gaps = 39/191 (20%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 Q P VYL+ +G IV +L+ + APKT +NF +L + Y G F Sbjct: 10 QPPNVYLE-----TSMGIIVLELYWKHAPKTCKNFAELA-----------RRGYYNGTKF 53 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HR++K+FMIQ GD + G+GG SIY + +DE F Sbjct: 54 HRIIKDFMIQGGD----------PTGTGRGGASIYGKQ----FEDELHPDLKF------- 92 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSD 182 L MAN G P+TN SQFF+T L+GKH+IFG+V G +V + +S Sbjct: 93 -TGAGILAMANAG-PDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQ 150 Query: 183 GVPESDVRISD 193 P DV+I Sbjct: 151 DRPVDDVKIIK 161 >2C3B-A nrPDB Length = 172 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 72/201 (35%), Positives = 92/201 (45%), Gaps = 41/201 (20%) Query: 6 LVYLDIS-----IDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGN 60 V+ D+ + +GRIV LF + PKT +NF +LC K Y+ + Sbjct: 4 QVFFDVEYAPVGTAETKVGRIVFNLFDKDVPKTAKNFRELC--------KRPAGEGYRES 55 Query: 61 GFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENL 120 FHR++ NFMIQ GD G G GG SIY DK F DEN Sbjct: 56 TFHRIIPNFMIQGGDFTRGN---------GTGGRSIYGDK--------------FADENF 92 Query: 121 G-EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVH--GKSVVRTIENC 177 + + L MAN G PNTN SQFFITT L+GKH +FG+V SVV+ IE Sbjct: 93 SRKHDKKGILSMANAG-PNTNGSQFFITTAVTSWLDGKHVVFGEVADEKSYSVVKEIEAL 151 Query: 178 RVDSDG-VPESDVRISDCGVW 197 S + +I +CG Sbjct: 152 GSSSGSVRSNTRPKIVNCGEL 172 >2OK3-A nrPDB Length = 161 Score = 178 bits (452), Expect = 3e-45, Method: Composition-based stats. Identities = 60/183 (32%), Positives = 85/183 (46%), Gaps = 35/183 (19%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 +G I ++F E+ PKT ENF LCA + Y G FHR +K FM+Q G Sbjct: 6 HTDVGDIKIEVFCERTPKTCENFLALCASN-----------YYNGCIFHRNIKGFMVQTG 54 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 D + G+GG SI+ K E + + + + MAN Sbjct: 55 D----------PTGTGRGGNSIWGKKFEDEYSE------------YLKHNVRGVVSMANN 92 Query: 135 GSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD-SDGVPESDVRISD 193 G PNTN SQFFIT PHL+ K+++FG+V+ G + +E V+ P +DV I D Sbjct: 93 G-PNTNGSQFFITYGKQPHLDMKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKD 151 Query: 194 CGV 196 + Sbjct: 152 ITI 154 >2FU0-A nrPDB Length = 160 Score = 176 bits (445), Expect = 2e-44, Method: Composition-based stats. Identities = 63/185 (34%), Positives = 87/185 (47%), Gaps = 34/185 (18%) Query: 12 SIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMI 71 +I +G I LF ++ KT +NF Y FHRV+K+FM+ Sbjct: 8 AIIYTTMGDIHISLFYKECKKTVQNF-----------SVHSINGYYNNCIFHRVIKHFMV 56 Query: 72 QAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGM 131 Q GD S G GG SI+ ++ +DE F + N +PF + M Sbjct: 57 QTGD----------PSGDGTGGESIWGNE----FEDEFFDHLN--------HSKPFMVSM 94 Query: 132 ANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRI 191 AN G PNTN SQFFITT P L+ KH++FG+V G +V IE R D P D++I Sbjct: 95 ANCG-PNTNGSQFFITTVPCPWLDFKHTVFGKVTQGSKIVLDIEKVRTDKRDKPLEDIKI 153 Query: 192 SDCGV 196 + + Sbjct: 154 LNIKI 158 >1W74-A nrPDB Length = 191 Score = 168 bits (424), Expect = 5e-42, Method: Composition-based stats. Identities = 60/189 (31%), Positives = 75/189 (39%), Gaps = 32/189 (16%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAG----DVKSPLKDQQYLSYKGNGFHRVVKNFM 70 G I LF APKT NF L G ++ Y G FHRV++ FM Sbjct: 29 HTNRGDIKIALFGNHAPKTVANFVGLAQGTKDYSTQNASGGPSGPFYDGAVFHRVIQGFM 88 Query: 71 IQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLG 130 IQ GD + K DE F+ +P+ L Sbjct: 89 IQGGDPTGTGRGGPG-----------------YKFADEFHPELQFD--------KPYLLA 123 Query: 131 MANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKS--VVRTIENCRVDSDGVPESD 188 MAN G P TN SQFFIT PHLN +H+IFG+V+ +S VV I D + P Sbjct: 124 MANAG-PGTNGSQFFITVGKTPHLNRRHTIFGEVIDAESQRVVEAISKTATDGNDRPTDP 182 Query: 189 VRISDCGVW 197 V I + Sbjct: 183 VVIESITIS 191 >1ZKC-A nrPDB Length = 197 Score = 167 bits (422), Expect = 9e-42, Method: Composition-based stats. Identities = 60/202 (29%), Positives = 85/202 (42%), Gaps = 42/202 (20%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 G + +L + PKT ENF +LC + Y G FHR ++NF+IQ Sbjct: 25 HTNKGDLNLELHCDLTPKTCENFIRLC-----------KKHYYDGTIFHRSIRNFVIQ-- 71 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDEN--LGEFVEPFTLGMA 132 D T ES+ F+DE L MA Sbjct: 72 ----------------------GGDPTGTGTGGESYWGKPFKDEFRPNLSHTGRGILSMA 109 Query: 133 NLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRIS 192 N G PN+N SQFFIT + +L+ KH+IFG+VV G V+ +EN D P++D Sbjct: 110 NSG-PNSNRSQFFITFRSCAYLDKKHTIFGRVVGGFDVLTAMENVESD----PKTDRPKE 164 Query: 193 DCGVWEKTMGVPLYNASNDQIG 214 + + T+ V Y ++ QI Sbjct: 165 EIRIDATTVFVDPYEEADAQIA 186 >4R3F-A nrPDB Length = 204 Score = 164 bits (416), Expect = 4e-41, Method: Composition-based stats. Identities = 57/202 (28%), Positives = 88/202 (43%), Gaps = 37/202 (18%) Query: 12 SIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMI 71 I G + +LF ++ P T NF + Y G FHR+V F+I Sbjct: 18 VIIHTTQGDLKVELFAKQTPLTCRNFLQ-----------HSLDGYYDGTIFHRLVPGFII 66 Query: 72 QAGDIVFGTQKDSSSSSVGKGGCSIY-----------ADKEEVKTDDESFCYGNFEDE-- 118 Q GD + G GG SIY ++ K + NF+DE Sbjct: 67 QGGD----------PTGTGHGGESIYDGGAFSGDLDPWPMDQRKGHNAGPMGVNFKDEFH 116 Query: 119 NLGEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV---VRTIE 175 + +F LGMAN G+P+TN SQFF T A LN K+++FG+V G ++ ++ E Sbjct: 117 SRLKFNRRGLLGMANEGAPDTNGSQFFFTLGKAEELNNKNTLFGRVAAGDTIYNLMKWGE 176 Query: 176 NCRVDSDGVPESDVRISDCGVW 197 ++ P+ V+I++ + Sbjct: 177 AELIEGTERPQYPVKITNIEIL 198 >2B71-A nrPDB Length = 196 Score = 164 bits (416), Expect = 5e-41, Method: Composition-based stats. Identities = 57/176 (32%), Positives = 81/176 (46%), Gaps = 34/176 (19%) Query: 16 KPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGD 75 +G +L+ +PKT NFY LC + Y FHRV+ NF+IQ GD Sbjct: 45 TNLGDFEVELYWYHSPKTCLNFYTLC-----------EMGFYDNTIFHRVIPNFVIQGGD 93 Query: 76 IVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLG 135 + GKGG SIY + E + + E + L M+N G Sbjct: 94 ----------PTGTGKGGKSIYGEYFEDEINKEL------------KHTGAGILSMSNNG 131 Query: 136 SPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRI 191 PNTN+SQFFIT PHL+GKH+IF +V + + I + + + P D++I Sbjct: 132 -PNTNSSQFFITLAPLPHLDGKHTIFARVSKNMTCIENIASVQTTATNKPIFDLKI 186 >2QER-A nrPDB Length = 185 Score = 164 bits (414), Expect = 8e-41, Method: Composition-based stats. Identities = 59/181 (32%), Positives = 83/181 (45%), Gaps = 36/181 (19%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G + +LF + PK +NF L A YK FH+ +K F+IQ GD Sbjct: 26 GDLKFELFCSQCPKACKNFLALSAS-----------GYYKNTIFHKNIKGFIIQGGD--- 71 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGS-- 136 + GKGG SIY DDE + ++ L MA+ G+ Sbjct: 72 -------PTGTGKGGESIYGRY----FDDEIYPELKYDRR--------GILSMASKGASK 112 Query: 137 -PNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCG 195 PNTN SQFFIT + P LNG++ IFG+++ G + T+ENC D P ++ I D Sbjct: 113 KPNTNGSQFFITYSSLPQLNGEYVIFGKLIDGFETLNTLENCPSDKSHKPIDEIIIKDIV 172 Query: 196 V 196 + Sbjct: 173 I 173 >4R3E-A nrPDB Length = 180 Score = 163 bits (412), Expect = 1e-40, Method: Composition-based stats. Identities = 61/198 (30%), Positives = 82/198 (41%), Gaps = 38/198 (19%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 IQ+P + + K G I +L+ ++APK NF +LC Y Sbjct: 8 IQEPPTNGKVLL-KTTAGDIDIELWSKEAPKACRNFIQLCL-----------EAYYDNTI 55 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVV F++Q GD + G GG SIY DE F Sbjct: 56 FHRVVPGFIVQGGD----------PTGTGSGGESIYG----APFKDEFHSRLRF------ 95 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV--VRTIENCRV 179 + MAN GS + N SQFF T A LN KH+IFG+V G +V + + + Sbjct: 96 --NRRGLVAMANAGS-HDNGSQFFFTLGRADELNNKHTIFGKVT-GDTVYNMLRLSEVDI 151 Query: 180 DSDGVPESDVRISDCGVW 197 D D P + +I C V Sbjct: 152 DDDERPHNPHKIKSCEVL 169 >2HQ6-A nrPDB Length = 185 Score = 161 bits (407), Expect = 5e-40, Method: Composition-based stats. Identities = 59/197 (29%), Positives = 80/197 (40%), Gaps = 38/197 (19%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGF 62 +P + + K G I +L+ ++APK NF +LC Y F Sbjct: 19 SEPPTNGKVLL-KTTAGDIDIELWSKEAPKACRNFIQLCL-----------EAYYDNTIF 66 Query: 63 HRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGE 122 HRVV F++Q GD + G GG SIY DE F Sbjct: 67 HRVVPGFIVQGGD----------PTGTGSGGESIYG----APFKDEFHSRLRF------- 105 Query: 123 FVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV--VRTIENCRVD 180 + MAN GS + N SQFF T A LN KH+IFG+V G +V + + +D Sbjct: 106 -NRRGLVAMANAGS-HDNGSQFFFTLGRADELNNKHTIFGKVT-GDTVYNMLRLSEVDID 162 Query: 181 SDGVPESDVRISDCGVW 197 D P + +I C V Sbjct: 163 DDERPHNPHKIKSCEVL 179 >2IF4-A nrPDB Length = 338 Score = 161 bits (406), Expect = 6e-40, Method: Composition-based stats. Identities = 37/163 (22%), Positives = 76/163 (46%), Gaps = 5/163 (3%) Query: 230 DDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFIN 289 D + + AA+ K G LFK++ A +Y ++ Y+ + K +++ + Sbjct: 169 DMTVEERIGAADRRKMDGNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMA-LA 227 Query: 290 LKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEA 349 +K +LN++ L L+RYD+AI + +L + KA +RRG + + ++D A Sbjct: 228 VKNPCHLNIAACLIKLKRYDEAIGHCNIVLTEEE----KNPKALFRRGKAKAELGQMDSA 283 Query: 350 LQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 D+ ++ PDD+ I + + + + +K ++ F Sbjct: 284 RDDFRKAQKYAPDDKAIRRELRALAEQEKALYQKQKEMYKGIF 326 >5Z56-z nrPDB Length = 472 Score = 154 bits (390), Expect = 5e-38, Method: Composition-based stats. Identities = 61/198 (30%), Positives = 82/198 (41%), Gaps = 38/198 (19%) Query: 2 IQDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 IQ+P + + K G I +L+ ++APK NF +LC Y Sbjct: 6 IQEPPTNGKVLL-KTTAGDIDIELWSKEAPKACRNFIQLCL-----------EAYYDNTI 53 Query: 62 FHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLG 121 FHRVV F++Q GD + G GG SIY DE F Sbjct: 54 FHRVVPGFIVQGGD----------PTGTGSGGESIYG----APFKDEFHSRLRF------ 93 Query: 122 EFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV--VRTIENCRV 179 + MAN GS + N SQFF T A LN KH+IFG+V G +V + + + Sbjct: 94 --NRRGLVAMANAGS-HDNGSQFFFTLGRADELNNKHTIFGKVT-GDTVYNMLRLSEVDI 149 Query: 180 DSDGVPESDVRISDCGVW 197 D D P + +I C V Sbjct: 150 DDDERPHNPHKIKSCEVL 167 >3BO7-A nrPDB Length = 201 Score = 151 bits (380), Expect = 7e-37, Method: Composition-based stats. Identities = 52/180 (28%), Positives = 79/180 (43%), Gaps = 22/180 (12%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G + +L + AP+ ++F +LCA + FHR ++NFMIQ G Sbjct: 16 GSLNIELHADMAPRACDSFLRLCAVK-----------YFDDTIFHRCIRNFMIQGGRAE- 63 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPN 138 ++ S V + SI +DE +N L MAN G + Sbjct: 64 -LRQPSKKKEVQQSPRSISGFPGGAPFEDEF--------DNRLVHQGIGVLSMANDGK-H 113 Query: 139 TNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCGVWE 198 +N S+FFIT + HLN KH+IFG+VV G V+R E D P ++ + V++ Sbjct: 114 SNLSEFFITFKSCEHLNNKHTIFGRVVGGLDVLRQWEKLETDKKDKPLKPPKVEEIIVFK 173 >5EX1-A nrPDB Length = 283 Score = 144 bits (364), Expect = 5e-35, Method: Composition-based stats. Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 22/183 (12%) Query: 10 DISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNF 69 +I + G I+ +L E AP F + + +Y G F+RV+ F Sbjct: 38 NIVVITTKYGDILIELNPEFAPGHVARFQDMV-----------KARAYNGKEFYRVIDGF 86 Query: 70 MIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYG---------NFEDENL 120 + Q G + K + + AD+ ++ +D+ F F+ E Sbjct: 87 VAQGG--IDAEDKKWPPLEIEHEQPLLEADQIQLLDNDDLFAEKVGFLNGFPVGFDAEKK 144 Query: 121 GEFVEPFTLGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVD 180 P L MA PNT + F+IT A +L+ ++FG+V+ G V+ ++ + Sbjct: 145 WLLHCPGMLAMARDSDPNTGGTDFYITLDAQRYLDRNMTVFGRVISGMQYVQKLQRGDKN 204 Query: 181 SDG 183 +G Sbjct: 205 IEG 207 >2NUL-A nrPDB Length = 164 Score = 142 bits (359), Expect = 2e-34, Method: Composition-based stats. Identities = 51/196 (26%), Positives = 71/196 (36%), Gaps = 48/196 (24%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 G IV K F +KAP+T +NF C + Y FHRV+ FMIQ G Sbjct: 5 HTNHGDIVIKTFDDKAPETVKNFLDYC-----------REGFYNNTIFHRVINGFMIQGG 53 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 G ++ ++ + + N G TL MA Sbjct: 54 GFEPGMKQKATKEPIK-------------------------NEANNGLKNTRGTLAMART 88 Query: 135 GSPNTNNSQFFITTYAAPHLNG--------KHSIFGQVVHGKSVVRTIENCRVDSDG--- 183 +P++ +QFFI LN + +F +VV G VV I+ G Sbjct: 89 QAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQ 148 Query: 184 -VPESDVRISDCGVWE 198 VP+ DV I V E Sbjct: 149 DVPKEDVIIESVTVSE 164 >3T1U-A nrPDB Length = 163 Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats. Identities = 49/190 (25%), Positives = 75/190 (39%), Gaps = 48/190 (25%) Query: 19 GRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVF 78 G I KLF +KAP+T NF + + Y G FHRV+ FMIQ G Sbjct: 9 GTITLKLFADKAPETAANFEQYV-----------KDGHYDGTIFHRVIDGFMIQGGGFEP 57 Query: 79 GTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLGSPN 138 G ++ S+ + + + N G + +T+ MA P+ Sbjct: 58 GMKQKSTRAPIK-------------------------NEANNGLSNKKYTIAMARTPDPH 92 Query: 139 TNNSQFFITTYAAPHLNG--------KHSIFGQVVHGKSVVRTIENCRVDS----DGVPE 186 + ++QFFI L+ +++FG+VV G VV I++ S VP Sbjct: 93 SASAQFFINVKDNAFLDHTAPTAHGWGYAVFGEVVEGTDVVDRIKSVATGSRAGHGDVPV 152 Query: 187 SDVRISDCGV 196 DV I + Sbjct: 153 DDVIIEKAEI 162 >2MVZ-A nrPDB Length = 148 Score = 136 bits (341), Expect = 2e-32, Method: Composition-based stats. Identities = 50/164 (30%), Positives = 66/164 (40%), Gaps = 37/164 (22%) Query: 16 KPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGD 75 + G+I +LF +AP T NF KL Y G FHRV+ F+ Q G Sbjct: 12 ENGGKIEFELFPNEAPVTVANFEKLAN-----------EGFYNGLTFHRVIPGFVSQGG- 59 Query: 76 IVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANLG 135 G G D + D N V + MA+ G Sbjct: 60 ---------CPRGNGTG--------------DAGYTIPCETDNNPHRHVT-GAMSMAHRG 95 Query: 136 SPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRV 179 +T + QFFI PHL+G H++FGQV G VVRT++N V Sbjct: 96 R-DTGSCQFFIVHEPQPHLDGVHTVFGQVTSGMDVVRTMKNGDV 138 >3S6M-A nrPDB Length = 167 Score = 135 bits (340), Expect = 3e-32, Method: Composition-based stats. Identities = 50/194 (25%), Positives = 73/194 (37%), Gaps = 48/194 (24%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 G I +L KAPKT ENF + Y G FHRV+ FMIQ G Sbjct: 9 HTNHGVIKLELDEAKAPKTVENFLNYV-----------KKGHYDGTIFHRVINGFMIQGG 57 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 G ++ + + + + N G + +T+ MA Sbjct: 58 GFEPGLKQKPTDAPIA-------------------------NEANNGLKNDTYTIAMART 92 Query: 135 GSPNTNNSQFFITTYAAPHLNG--------KHSIFGQVVHGKSVVRTIENCRVDSDG--- 183 P++ +QFFI LN +++FG+VV G+ +V I+ + S G Sbjct: 93 NDPHSATAQFFINVNDNEFLNHSSPTPQGWGYAVFGKVVEGQDIVDKIKAVKTGSKGFHQ 152 Query: 184 -VPESDVRISDCGV 196 VP DV I V Sbjct: 153 DVPNDDVVIEKAVV 166 >5EX2-A nrPDB Length = 271 Score = 125 bits (314), Expect = 3e-29, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 70/174 (40%), Gaps = 31/174 (17%) Query: 25 LFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVFGTQKDS 84 ++ E AP+ N V++ L Y G FHRV+ FM Q GDI ++ Sbjct: 35 VYIELAPEIAPNHVAQIRKVVRTGL-------YSGTKFHRVISGFMAQGGDIAATLGREP 87 Query: 85 SSSSVGKG----------GCSIYADKEEVKTDDESFCYG-----------NFEDENLGEF 123 +V ++ ++++ K+ F G N+ ++ E Sbjct: 88 DLEAVDGEFVFRRDPKSIVLTVINEEDQTKSQYTGFYNGFPIETRQDELANYSEDKRVES 147 Query: 124 VEPFT---LGMANLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTI 174 P + MA PN+ QFF+ + L+ K+S +G+++ G V +++ Sbjct: 148 WMPHCAGVVSMARTNDPNSGKDQFFLMRDESRFLDRKYSSWGRMLEGLDVAKSL 201 >1VAI-A nrPDB Length = 166 Score = 121 bits (303), Expect = 6e-28, Method: Composition-based stats. Identities = 42/192 (21%), Positives = 61/192 (31%), Gaps = 45/192 (23%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 G I +L ++KAP + +NF Y FHRV+ FMIQ G Sbjct: 10 TTSAGNIELELDKQKAPVSVQNFVDYVNS-----------GFYNNTTFHRVIPGFMIQGG 58 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 Q+ + + + + G T+ MA Sbjct: 59 GFTEQMQQKKPNPPIK-------------------------NEADNGLRNTRGTIAMART 93 Query: 135 GSPNTNNSQFFITTYAAPHL-----NGKHSIFGQVVHGKSVVRTIENCRVDSDG----VP 185 ++ SQFFI L + +++FG+VV G V I G VP Sbjct: 94 ADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVADKISQVPTHDVGPYQNVP 153 Query: 186 ESDVRISDCGVW 197 V I V Sbjct: 154 SKPVVILSATVL 165 >3BKP-A nrPDB Length = 232 Score = 121 bits (302), Expect = 7e-28, Method: Composition-based stats. Identities = 48/208 (23%), Positives = 72/208 (34%), Gaps = 50/208 (24%) Query: 15 KKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAG 74 +G + +L+ + P NF +LC Y FHRVVK+F++Q G Sbjct: 27 HTSLGDLDVELWARECPLACRNFVQLCL-----------EGYYVNTIFHRVVKDFIVQGG 75 Query: 75 DIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMANL 134 D + G+GG D D E+ F +G+ANL Sbjct: 76 D----------PTGTGRGGADTTFD--GKPFDVETHPRLKFRYR--------GLVGVANL 115 Query: 135 G-------------SPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSV-VRTIENCRVD 180 G S TN +QFFIT A LN +++FG+V + + V Sbjct: 116 GRSSKDAENDERGRSLGTNGNQFFITLARADVLNNAYTLFGKVTGHTLYNLMKFNDLEVG 175 Query: 181 SDGVPESDVRISDCGVWEKTMGVPLYNA 208 + P + I V + Sbjct: 176 KEDRPMTPPFIKSVDVL-----WNPFED 198 >2OSE-A nrPDB Length = 234 Score = 117 bits (293), Expect = 7e-27, Method: Composition-based stats. Identities = 47/208 (22%), Positives = 76/208 (36%), Gaps = 31/208 (14%) Query: 3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDV-------KSPLKDQQYL 55 ++P VY+DI ++ + IGR+ KLFR+ P ENF +L G K +++ Sbjct: 13 KNPRVYMDIVLNNEIIGRLQIKLFRDAFPAGVENFVQLTNGKTYRVNSNGTGKYKYNRHI 72 Query: 56 --SYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYG 113 +Y+G FH V+ N I +GDI + + + ++ D Sbjct: 73 NRTYEGCKFHNVLHNNYIVSGDIYNSNGSSAGTVYCDEPIPPVFGDYFYPHESKGLLSLV 132 Query: 114 NFEDENLGEFVEPFTLGMANLGSPNTNNSQFFITTYA------APHLNGKHSIFGQVVHG 167 + DE+ + + S F IT L+ + GQV G Sbjct: 133 PYTDESGNRYYD----------------STFMITLDDIRPSNVLDELDRDQVVIGQVYGG 176 Query: 168 KSVVRTIENCRVDSDGVPESDVRISDCG 195 V+ I + G I CG Sbjct: 177 LDVLDKINSMIKPYAGRKYPTFSIGKCG 204 >5JJT-A nrPDB Length = 479 Score = 102 bits (255), Expect = 2e-22, Method: Composition-based stats. Identities = 34/146 (23%), Positives = 61/146 (41%), Gaps = 24/146 (16%) Query: 240 ANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKI-YLNL 298 A K FK YS+A Y K++ +N + + N Sbjct: 9 AEEFKSQANEAFKGHKYSSAIDLYTKAIE-------------------LNSNNAVYWANR 49 Query: 299 SLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKE 358 + LE Y AI A+ +E+D+ +K YYRRG +YL + +AL+D+ K Sbjct: 50 AFAHTKLEEYGSAIQDASKAIEVDS----RYSKGYYRRGAAYLAMGKFKDALKDFQQVKR 105 Query: 359 KNPDDEVIEQRIEYVNRLIEENKEKT 384 +P+D ++++ + + + K + Sbjct: 106 LSPNDPDATRKLKECEKAVMKLKFEE 131 >5MGX-E nrPDB Length = 290 Score = 89.1 bits (219), Expect = 3e-18, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 62/169 (36%), Gaps = 5/169 (2%) Query: 224 DDTHFGDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKER 283 D + + AN +E G +++ D+ A Y ++ I + D+ E Sbjct: 115 DGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSS-AKVDMTFEE 173 Query: 284 NIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKK 343 Q + LK+K NL+ L+ Y A+ + +LE D KA +R+G ++ Sbjct: 174 EAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLE----HQPDNIKALFRKGKVLAQQ 229 Query: 344 KRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 EA+ + P ++ I + + + + K Sbjct: 230 GEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKML 278 >4JA9-A nrPDB Length = 488 Score = 85.2 bits (209), Expect = 4e-17, Method: Composition-based stats. Identities = 40/164 (24%), Positives = 66/164 (40%), Gaps = 26/164 (15%) Query: 226 THFGDDDFGK-ALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERN 284 +H D+ + L+ A +K FK KDY NA Y +++ Sbjct: 2 SHMRDEPPAEGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIE---------------- 45 Query: 285 IQFINLKMKIYL-NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKK 343 +N IY N SL E Y A+ AT +E+D K YYRR S + Sbjct: 46 ---LNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDK----KYIKGYYRRAASNMAL 98 Query: 344 KRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKN 387 + AL+DY + P+D+ + + + +++++ K R Sbjct: 99 GKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVK-QKAFERAI 141 >1A17-A nrPDB Length = 166 Score = 80.2 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 40/153 (26%), Positives = 61/153 (39%), Gaps = 25/153 (16%) Query: 236 ALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIY 295 AL+ A +K FK KDY NA Y +++ +N IY Sbjct: 9 ALKRAEELKTQANDYFKAKDYENAIKFYSQAIE-------------------LNPSNAIY 49 Query: 296 L-NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 N SL E Y A+ AT +E+D K YYRR S + + AL+DY Sbjct: 50 YGNRSLAYLRTECYGYALGDATRAIELDK----KYIKGYYRRAASNMALGKFRAALRDYE 105 Query: 355 FCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKN 387 + P D+ + + + N++++ K R Sbjct: 106 TVVKVKPHDKDAKMKYQECNKIVK-QKAFERAI 137 >6FO1-G nrPDB Length = 665 Score = 77.9 bits (190), Expect = 7e-15, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 229 GDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFI 288 + + + A K+ G FK+ Y A Y + + P Sbjct: 271 KQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLP----------- 319 Query: 289 NLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDE 348 N ++ +++Y++A T + +D +KA+ RRG + +L+E Sbjct: 320 -------ANRAMAYLKIQKYEEAEKDCTQAILLDG----SYSKAFARRGTARTFLGKLNE 368 Query: 349 ALQDYIFCKEKNPDDEVIEQRIEYVNRLIEEN 380 A QD+ P ++ + + + + E Sbjct: 369 AKQDFETVLLLEPGNKQAVTELSKIKKELIEK 400 Score = 76.3 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 55/145 (37%), Gaps = 26/145 (17%) Query: 231 DDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINL 290 D KAL ++KE G FK+ Y A Y K + N Sbjct: 128 VDSQKAL----VLKEKGNKYFKQGKYDEAIDCYTK----------------GMDADPYNP 167 Query: 291 KMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEAL 350 + N + F L+++ A + + NR KAY RRG + ++L+EA Sbjct: 168 VLPT--NRASAYFRLKKFAVAESDCNLAVAL----NRSYTKAYSRRGAARFALQKLEEAK 221 Query: 351 QDYIFCKEKNPDDEVIEQRIEYVNR 375 +DY E P++ + +++ Sbjct: 222 KDYERVLELEPNNFEATNELRKISQ 246 Score = 31.3 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 20/45 (44%) Query: 160 IFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVP 204 +F ++VV+ I+N P V I + G +T+ VP Sbjct: 406 VFLDSTQRQNVVKPIDNPPHPGSTKPLKKVIIEETGNLIQTIDVP 450 >4I2W-A nrPDB Length = 961 Score = 76.7 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 20/153 (13%) Query: 237 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 296 ++ A I++ G K +DY A Y ++L + L+ +Y Sbjct: 5 VQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEDK-------------ALRPVLYR 51 Query: 297 NLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFC 356 N ++ + ++ A T LE D KA +RR + + + A QD Sbjct: 52 NRAMARLKRDDFEGAQSDCTKALEFDGA----DVKALFRRSLAREQLGNVGPAFQDAKEA 107 Query: 357 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNIS 389 +P+D+ I +E + RL++ N +K ++ S Sbjct: 108 LRLSPNDKGI---VEVLQRLVKANNDKIKQTTS 137 >2Y4T-A nrPDB Length = 450 Score = 61.3 bits (147), Expect = 7e-10, Method: Composition-based stats. Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 18/150 (12%) Query: 235 KALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKI 294 K ++ N + ES L + Y++A KY + + E V + I Sbjct: 252 KQVKKLNKLIESAEELIRDGRYTDATSKYESVMK-TEPSIAEYTVRSKERI--------C 302 Query: 295 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 + E+ +AI + +L+M+ D A R +YL ++ DEA+QDY Sbjct: 303 H-----CFSKDEKPVEAIRVCSEVLQME----PDNVNALKDRAEAYLIEEMYDEAIQDYE 353 Query: 355 FCKEKNPDDEVIEQRIEYVNRLIEENKEKT 384 +E N +D+ I + +E RL+++++++ Sbjct: 354 TAQEHNENDQQIREGLEKAQRLLKQSQKRD 383 Score = 38.6 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 40/92 (43%), Gaps = 9/92 (9%) Query: 294 IYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDY 353 Y + V + + A+ T ++++ D A +RG+ LK+ +LDEA D+ Sbjct: 62 AYYRRATVFLAMGKSKAALPDLTKVIQL----KMDFTAARLQRGHLLLKQGKLDEAEDDF 117 Query: 354 IFCKEKNP---DDEVIEQRIEYVN--RLIEEN 380 + NP +++ + ++ + + + Sbjct: 118 KKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQ 149 Score = 38.2 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 34/96 (35%), Gaps = 7/96 (7%) Query: 295 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 +L L L + DA+ ++ D D AYYRR +L + AL D Sbjct: 29 HLELGKKLLAAGQLADALSQFHAAVDGD----PDNYIAYYRRATVFLAMGKSKAALPDLT 84 Query: 355 FCKEKNPDDEVIEQR---IEYVNRLIEENKEKTRKN 387 + D + + ++E ++ +K Sbjct: 85 KVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKV 120 >3RFY-A nrPDB Length = 369 Score = 58.2 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 40/189 (21%), Positives = 67/189 (35%), Gaps = 30/189 (15%) Query: 7 VYLDISIDKKP-----IGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNG 61 V + + I P + RIV L AP T NF L Y G Sbjct: 173 VDMKVKIKDNPNIEDCVFRIV--LDGYNAPVTAGNFVDLVERH-----------FYDGME 219 Query: 62 FHRVVKNFMIQAGDIVFGTQK--DSSSSSVGKGGCSIYADKEEVKTDDESFCY-GNFEDE 118 R F++Q GD + D S+ I E+ + G ++ + Sbjct: 220 IQRS-DGFVVQTGDPEGPAEGFIDPSTEKTRTVPLEIMVTGEKTPFYGSTLEELGLYKAQ 278 Query: 119 NLGEFVEPFTLGMANLGSPN-TNNSQFF-------ITTYAAPHLNGKHSIFGQVVHGKSV 170 + F T+ MA N + +SQ F +T + L+G++++FG V + Sbjct: 279 VVIPFNAFGTMAMAREEFENDSGSSQVFWLLKESELTPSNSNILDGRYAVFGYVTDNEDF 338 Query: 171 VRTIENCRV 179 + ++ V Sbjct: 339 LADLKVGDV 347 >2C2L-A nrPDB Length = 281 Score = 57.9 bits (138), Expect = 8e-09, Method: Composition-based stats. Identities = 25/126 (19%), Positives = 45/126 (35%), Gaps = 22/126 (17%) Query: 239 AANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNL 298 +A +KE G LF + Y A Y +++ P V Y N Sbjct: 3 SAQELKEQGNRLFVGRKYPEAAACYGRAIT------RNPLVAVY------------YTNR 44 Query: 299 SLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKE 358 +L +++ + A+ LE+D KA++ G L+ + DEA+ + Sbjct: 45 ALCYLKMQQPEQALADCRRALELDG----QSVKAHFFLGQCQLEMESYDEAIANLQRAYS 100 Query: 359 KNPDDE 364 + Sbjct: 101 LAKEQR 106 Score = 28.6 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 25/77 (32%), Gaps = 4/77 (5%) Query: 306 ERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEV 365 +Y +A + N A Y R YLK ++ ++AL D E + Sbjct: 18 RKYPEAAACYGRAI----TRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVK 73 Query: 366 IEQRIEYVNRLIEENKE 382 + +E E Sbjct: 74 AHFFLGQCQLEMESYDE 90 >2GW1-A nrPDB Length = 514 Score = 51.3 bits (121), Expect = 7e-07, Method: Composition-based stats. Identities = 31/145 (21%), Positives = 51/145 (35%), Gaps = 26/145 (17%) Query: 243 IKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVL 302 +K+ G F+ K Y +A Y N+ E +P Y NLS Sbjct: 9 LKDKGNQFFRNKKYDDAIKYY----NWALELKEDPVF---------------YSNLSACY 49 Query: 303 FNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPD 362 ++ + +T LE+ D +K RR ++ + +A+ D N D Sbjct: 50 VSVGDLKKVVEMSTKALEL----KPDYSKVLLRRASANEGLGKFADAMFDL-SVLSLNGD 104 Query: 363 --DEVIEQRIEYVNRLIEENKEKTR 385 D IE +E +K K + Sbjct: 105 FNDASIEPMLERNLNKQAMSKLKEK 129 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 61/148 (41%), Gaps = 6/148 (4%) Query: 216 DVYEEYPDDDTHFGDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMP 275 ++Y+ P+ D+ F KA + K K+ ++ ++ Sbjct: 196 NLYKRSPES-YDKADESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKFLKNDPL 254 Query: 276 EPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYR 335 D ++ I+ + ++ Y+ ++L++ + + Y L++D+ + + YY Sbjct: 255 GAHEDIKKAIE-LFPRVNSYIYMALIMADRNDSTEYYNYFDKALKLDS----NNSSVYYH 309 Query: 336 RGNSYLKKKRLDEALQDYIFCKEKNPDD 363 RG + D+A +D+ KE +P++ Sbjct: 310 RGQMNFILQNYDQAGKDFDKAKELDPEN 337 >6B85-J nrPDB Length = 223 Score = 49.0 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 40/97 (41%), Gaps = 5/97 (5%) Query: 294 IYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDY 353 +L L VL L+R D+A +E+ + A A+ G K RLDEA + Y Sbjct: 117 AWLLLGSVLEKLKRLDEAAEAYKKAIEL----KPNDASAWKELGKVLEKLGRLDEAAEAY 172 Query: 354 IFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISK 390 E +P+D + + V + ++ + K Sbjct: 173 KKAIELDPEDAEAWKELGKVLEKLGR-LDEAAEAYKK 208 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 44/117 (37%), Gaps = 22/117 (18%) Query: 247 GTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLE 306 G++L K K A Y+K++ + L VL L Sbjct: 122 GSVLEKLKRLDEAAEAYKKAIELKPND------------------ASAWKELGKVLEKLG 163 Query: 307 RYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDD 363 R D+A +E+D + A+A+ G K RLDEA + Y E +P+D Sbjct: 164 RLDEAAEAYKKAIELD----PEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 >4CGU-A nrPDB Length = 112 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 32/110 (29%), Gaps = 20/110 (18%) Query: 237 LEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYL 296 + KE G LFK+ Y A Y + + + + Y Sbjct: 2 MSQFEKQKEQGNSLFKQGLYREAVHCYDQLIT-------------AQPQNPVG-----YS 43 Query: 297 NLSLVLFNLERYDDAIMYATYLLEMDNVPNRD--QAKAYYRRGNSYLKKK 344 N ++ L L Y AI L + ++K YR + Sbjct: 44 NKAMALIKLGEYTQAIQMCQQGLRYTSTAEHVAIRSKLQYRLELAQGAVG 93 >1W3B-A nrPDB Length = 388 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 43/140 (30%), Gaps = 22/140 (15%) Query: 223 DDDTHFGDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKE 282 D HF + A G + ++ A YR +L +PD Sbjct: 50 DRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALR------LKPDFIDG 103 Query: 283 RNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLK 342 Y+NL+ L + A+ L+ + ++ GN Sbjct: 104 ------------YINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL----GNLLKA 147 Query: 343 KKRLDEALQDYIFCKEKNPD 362 RL+EA Y+ E P+ Sbjct: 148 LGRLEEAKACYLKAIETQPN 167 >5IWY-A nrPDB Length = 158 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 30/147 (20%), Positives = 56/147 (38%), Gaps = 18/147 (12%) Query: 163 QVVHGKSVVRTIENCR--VDSDGVPESDVRISDCGVWEKTM-GVPLYNASNDQIG----G 215 ++ G V + +E + +P G+ + V L+ ++ +G G Sbjct: 3 RIGQGFDVHQLVEGRPLIIGGIEIPYEK------GLLGHSDADVLLHTVADACLGAVGEG 56 Query: 216 DVYEEYPDDDTHFGDDDFGKALEAA-NIIKESGTLLFKKKDYSNAFF-KYRKSLNYINEY 273 D+ + +PD D F D D K L+ I+K+ G +L + + K L YI + Sbjct: 57 DIGKHFPDTDPEFKDADSFKLLQHVWGIVKQKGYVL---GNIDCTIIAQKPKMLPYIEDM 113 Query: 274 MPEPDVDKERNIQFINLKMKIYLNLSL 300 E ++ +N+K L Sbjct: 114 RKRIAEGLEADVSQVNVKATTTEKLGF 140 >5KHR-J nrPDB Length = 620 Score = 37.8 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 44/132 (33%), Gaps = 13/132 (9%) Query: 242 IIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLV 301 ++ E G + F+ ++ A + +L I E VDK + NL V Sbjct: 404 VMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWE---------PLLNNLGHV 454 Query: 302 LFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNP 361 L++Y +A+ Y L V A Y G + + A+ + Sbjct: 455 CRKLKKYAEALDYHRQAL----VLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRR 510 Query: 362 DDEVIEQRIEYV 373 DD + + Sbjct: 511 DDTFSVTMLGHC 522 >4I9E-A nrPDB Length = 383 Score = 37.8 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 50/132 (37%), Gaps = 29/132 (21%) Query: 260 FFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLL 319 +Y ++++ + + +K+ + L N+ L + +Y+DAI Y + Sbjct: 197 LKQYEDAISHFQKAYSMAEAEKQPQLMGRTLY-----NIGLCKNSQSQYEDAIPYFKRAI 251 Query: 320 EM--DNVPNRDQAKAYYRRGNSYLKKKRLDEA-------------------LQDYIFCKE 358 + ++ +AY+ + K ++D+A L ++ F K Sbjct: 252 AVFEESNILPSLPQAYFLITQIHYKLGKIDKAHEYHSKGMAYSQKAGDVIYLSEFEFLKS 311 Query: 359 KN---PDDEVIE 367 PD+E I+ Sbjct: 312 LYLSGPDEEAIQ 323 Score = 37.1 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 17/124 (13%), Positives = 40/124 (32%), Gaps = 8/124 (6%) Query: 236 ALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKM-KI 294 L E FK + Y Y + + + + N+++ + Sbjct: 132 KLIFVKDRIEKAEFFFK-----MSESYYYMKQTYFSMDYARQAYEIYKEHEAYNIRLLQC 186 Query: 295 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKA--YYRRGNSYLKKKRLDEALQD 352 + + +L++Y+DAI + M + Q Y G + + ++A+ Sbjct: 187 HSLFATNFLDLKQYEDAISHFQKAYSMAEAEKQPQLMGRTLYNIGLCKNSQSQYEDAIPY 246 Query: 353 YIFC 356 + Sbjct: 247 FKRA 250 >5WQL-B nrPDB Length = 278 Score = 37.8 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 47/131 (35%), Gaps = 9/131 (6%) Query: 257 SNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLK--MKIYLN-LSLVLFNLERYDDAIM 313 A Y + + Y + + + + Q + ++ M N L + L +D A Sbjct: 44 ERAQLLYERGVLY--DSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYE 101 Query: 314 YATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRIEYV 373 +LE+D A+ RG + R A D + + +P+D + Sbjct: 102 AFDSVLELD----PTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLA 157 Query: 374 NRLIEENKEKT 384 + ++E + K Sbjct: 158 EQKLDEKQAKE 168 >4I1A-A nrPDB Length = 391 Score = 37.1 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 54/142 (38%), Gaps = 17/142 (11%) Query: 255 DYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMY 314 +Y A ++ KSL ++ KE NI+ +L ++N+ + L+ Y A + Sbjct: 199 EYERALEQFLKSL----------EISKESNIE--HLIAMSHMNIGICYDELKEYKKASQH 246 Query: 315 ATYLLEM-DNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN--PDDEVIEQRIE 371 LE+ + + K + K++ + AL + + DD+ + + Sbjct: 247 LILALEIFEKSKHSFLTKTLFTLTYVEAKQQNYNVALIYFRKGRFIADKSDDKEYSAKFK 306 Query: 372 YVNRLIEENKEKTRKNISKFFS 393 + L + + I FS Sbjct: 307 ILEGLFFS--DGETQLIKNAFS 326 >5JZ6-A nrPDB Length = 429 Score = 37.1 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 24/164 (14%), Positives = 53/164 (32%), Gaps = 19/164 (11%) Query: 230 DDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFIN 289 D L+AA ++ K+ A +++ + P+ + Q Sbjct: 9 DKTIKAELDAAEKLR-------KRGKIEEAVNAFKELVR----KYPQSPRARYGKAQ--- 54 Query: 290 LKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEA 349 +L+ + E AI + + +VP + RR + + + Sbjct: 55 ----CEDDLAEKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGS 110 Query: 350 LQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFFS 393 L + P+D ++ + LI +N + +K + S Sbjct: 111 LLTLQRLVQLFPNDTSLKNDLGVGYLLIGDN-DNAKKVYEEVLS 153 >4UZY-A nrPDB Length = 651 Score = 36.7 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 22/153 (14%), Positives = 52/153 (33%), Gaps = 26/153 (16%) Query: 238 EAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLN 297 E + + +G ++FK+ + A K+ ++ + Y PE N Sbjct: 145 EDPDTMVNTGCIMFKEGKFEAARQKFNDAVQALG-YQPELLY-----------------N 186 Query: 298 LSLVLFNLERYDDAIMYATYLLEMDNVPNR-----DQAKAYYRR--GNSYLKKKRLDEAL 350 ++L + +++ A+ + ++E + R GNS K+ Sbjct: 187 IALCYYKTKQFGPALKHLAEIIEKAVREHPELSVGSNTDGMEVRSVGNSQTLKETALIEA 246 Query: 351 QDYIFCKEKNPDD-EVIEQRIEYVNRLIEENKE 382 + E + E ++ + + EE + Sbjct: 247 FNLKAAIEYTMKNVEAAKEALTDMPPRAEEELD 279 Score = 29.4 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 26/63 (41%), Gaps = 4/63 (6%) Query: 302 LFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNP 361 L +++ +AI + Y L+ NVP A + G Y + D A Q Y P Sbjct: 27 LIKEQKFAEAIQHLQYQLQ--NVPESRAALSLL--GYCYYYTGQYDMASQMYEQLVTLYP 82 Query: 362 DDE 364 +E Sbjct: 83 SNE 85 >6AF0-A nrPDB Length = 939 Score = 35.5 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 32/104 (30%), Gaps = 5/104 (4%) Query: 294 IYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQ-----AKAYYRRGNSYLKKKRLDE 348 +Y+N+ + L ++ AI L + N + + +G + Sbjct: 775 VYVNMGHIYAELRQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYKM 834 Query: 349 ALQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTRKNISKFF 392 AL PD + + +V I R++ F Sbjct: 835 ALDQAKKAVAVAPDQLHFKFNVAFVQIQIALVLHSMRESERNSF 878 >4JHR-A nrPDB Length = 333 Score = 35.5 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 51/143 (35%), Gaps = 7/143 (4%) Query: 225 DTHFGDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKE-- 282 +TH+ +F A+ A K A+ + ++ E+ + K+ Sbjct: 119 NTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL 178 Query: 283 ---RNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATY--LLEMDNVPNRDQAKAYYRRG 337 R ++ ++ + +L L+ Y+ AI Y + + + +A + G Sbjct: 179 LLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGRACWSLG 238 Query: 338 NSYLKKKRLDEALQDYIFCKEKN 360 N+Y D+A+ E + Sbjct: 239 NAYTALGNHDQAMHFAEKHLEIS 261 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 4/85 (4%) Query: 289 NLKMKIYLNLSLVLFNLERYDDAIMYATYLLEM--DNVPNRDQAKAYYRRGNSYLKKKRL 346 + + + NL + L + DA++ L + + + +AY GN+Y+ Sbjct: 108 AAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEF 167 Query: 347 DEALQDYIFCKEKNPD--DEVIEQR 369 + A + Y D +E + Sbjct: 168 ETASEYYKKTLLLARQLKDRAVEAQ 192 >5AEM-A nrPDB Length = 447 Score = 35.1 bits (79), Expect = 0.048, Method: Composition-based stats. Identities = 20/83 (24%), Positives = 33/83 (39%), Gaps = 3/83 (3%) Query: 295 YLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYI 354 Y + L E+Y +AI + T LL ++ D K R Y + + + A + Y Sbjct: 351 YFEAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPLAR---CYKEIESYETAKEFYE 407 Query: 355 FCKEKNPDDEVIEQRIEYVNRLI 377 + PDD I + V + Sbjct: 408 LAIKSEPDDLDIRVSLAEVYYRL 430 Score = 34.4 bits (77), Expect = 0.10, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 37/90 (41%), Gaps = 13/90 (14%) Query: 292 MKIYLN---------LSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLK 342 + +LN ++++ +L+ AI + ++ + N + ++ YRR Y K Sbjct: 68 LAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISL----NPMEWESIYRRSMLYKK 123 Query: 343 KKRLDEALQDYIFCKEKNPDDEVIEQRIEY 372 +L AL + NP D I + + Sbjct: 124 TGQLARALDGFQRLYMYNPYDANILRELAI 153 >5G04-F nrPDB Length = 824 Score = 34.7 bits (78), Expect = 0.077, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 28/74 (37%), Gaps = 4/74 (5%) Query: 306 ERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEV 365 E D A+ + + N A+Y G Y K+++ A + + NP V Sbjct: 615 EELDKALACFRNAIRV----NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV 670 Query: 366 IEQRIEYVNRLIEE 379 + I V +++ Sbjct: 671 LLCHIGVVQHALKK 684 >5G04-X nrPDB Length = 599 Score = 34.0 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 17/137 (12%), Positives = 50/137 (36%), Gaps = 20/137 (14%) Query: 241 NIIKESGTLLFKKKDYSNAFFKYRKS-------LNYINEY-MPEPDVDKERNIQFINLKM 292 +++ L F+ D N+ K+ ++ + ++ Y + +++ + ++ Sbjct: 272 DLLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRL 331 Query: 293 KIYLN-------LSLVL-FNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKK 344 + +S F +RY A+ +++++ +A +G + Sbjct: 332 FNISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSV----QALLLKGAALRNMG 387 Query: 345 RLDEALQDYIFCKEKNP 361 R+ EA+ + P Sbjct: 388 RVQEAIIHFREAIRLAP 404 >5CTR-A nrPDB Length = 338 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 35/236 (14%), Positives = 72/236 (30%), Gaps = 35/236 (14%) Query: 170 VVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFG 229 + +E VD + + + + G + T V ++ A Y +Y F Sbjct: 112 YLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQA---------YLDYLRRRVDFK 162 Query: 230 DDDFGKALEAANIIKESGTLLFK---KKDYSNA-------FFKYRKSLNYINEYMPEPDV 279 D K LE K ++ ++ + + + + M Sbjct: 163 Q-DSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARIEARLCNNM---QK 218 Query: 280 DKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNS 339 +E + Y N+ L +NLER + L D + Sbjct: 219 ARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHV---CEV 275 Query: 340 YLKKKRLDEALQDYIFCKEKNPDD---------EVIEQRIEYVNRLIEENKEKTRK 386 L +R + +L+D+ +K + E+ V + E+ +++ R Sbjct: 276 LLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKRA 331 >5CTQ-A nrPDB Length = 561 Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats. Identities = 35/236 (14%), Positives = 72/236 (30%), Gaps = 35/236 (14%) Query: 170 VVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFG 229 + +E VD + + + + G + T V ++ A Y +Y F Sbjct: 335 YLLAMERHGVDHQVISVTFEKALNAGFIQATDYVEIWQA---------YLDYLRRRVDFK 385 Query: 230 DDDFGKALEAANIIKESGTLLFK---KKDYSNA-------FFKYRKSLNYINEYMPEPDV 279 D K LE K ++ ++ + + + + M Sbjct: 386 Q-DSSKELEELRAAFTRALEYLKQEVEERFNESGDPSCVIMQNWARIEARLCNNM---QK 441 Query: 280 DKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNS 339 +E + Y N+ L +NLER + L D + Sbjct: 442 ARELWDSIMTRGNAKYANMWLEYYNLERAHGDTQHCRKALHRAVQCTSDYPEHV---CEV 498 Query: 340 YLKKKRLDEALQDYIFCKEKNPDD---------EVIEQRIEYVNRLIEENKEKTRK 386 L +R + +L+D+ +K + E+ V + E+ +++ R Sbjct: 499 LLTMERTEGSLEDWDIAVQKTETRLARVNEQRMKAAEKEAALVQQEEEKAEQRKRA 554 >5LK3-A nrPDB Length = 495 Score = 32.8 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 29/76 (38%), Gaps = 13/76 (17%) Query: 148 TYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPE--SDVRISDCGVWEKTMGVPL 205 AAPHL+ V+G S IEN +V DG P+ G W + Sbjct: 409 HAAAPHLDK--------VNGIS---EIENSKVYDDGAPQCGIKCWFVKSGEWISGIFSGN 457 Query: 206 YNASNDQIGGDVYEEY 221 + +D G + ++ Sbjct: 458 GGSDDDDKAGWSHPQF 473 >5OJ8-A nrPDB Length = 255 Score = 32.4 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 39/111 (35%), Gaps = 12/111 (10%) Query: 262 KYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEM 321 KY+ + N +N+ + + ++ + + NL+++ +Y +A LE+ Sbjct: 107 KYKDAANLLNDALAIREKTLGKDHPAVAATLN---NLAVLYGKRGKYKEAEPLCKRALEI 163 Query: 322 DN----VPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN-----PDD 363 + D AK + + +E Y E PDD Sbjct: 164 REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDD 214 >5DSE-A nrPDB Length = 837 Score = 32.4 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 28/92 (30%), Gaps = 4/92 (4%) Query: 294 IYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDY 353 I+L+ + V + + +A Y RG + +DEA + Y Sbjct: 692 IWLHAAEVYIGIGKPAEATACTQEA----ANLFPMSHNVLYMRGQIAELRGSMDEARRWY 747 Query: 354 IFCKEKNPDDEVIEQRIEYVNRLIEENKEKTR 385 +P QR+ + + + Sbjct: 748 EEALAISPTHVKSMQRLALILHQLGRYSLAEK 779 >5GM6-b nrPDB Length = 301 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 6/22 (27%), Positives = 13/22 (59%) Query: 19 GRIVCKLFREKAPKTTENFYKL 40 G I +L+ ++ P+T + F + Sbjct: 20 GNIAIELWAKECPETCKRFLSM 41 >1HH8-A nrPDB Length = 213 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 19/113 (16%), Positives = 43/113 (38%), Gaps = 8/113 (7%) Query: 269 YINEYMPEPDVD-KERNIQFINLKMK---IYLNLSLVLFNLERYDDAIMYATYLLEMDNV 324 + + D K F ++ I N+ + L+ +A T + D Sbjct: 10 WNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFTRSINRDKH 69 Query: 325 PNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLI 377 AY++RG Y + ++ D A++D + +++I+ +I + + Sbjct: 70 LAV----AYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKL 118 >3NF1-A nrPDB Length = 311 Score = 32.0 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 39/111 (35%), Gaps = 12/111 (10%) Query: 262 KYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEM 321 KY+ + N +N+ + + ++ + + NL+++ +Y +A LE+ Sbjct: 84 KYKDAANLLNDALAIREKTLGKDHPAVAATLN---NLAVLYGKRGKYKEAEPLCKRALEI 140 Query: 322 DN----VPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN-----PDD 363 + D AK + + +E Y E PDD Sbjct: 141 REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDD 191 >6AHD-N nrPDB Length = 941 Score = 31.7 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 44/125 (35%), Gaps = 4/125 (3%) Query: 269 YINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFN---LERYDDAIMYATYLLEMDNVP 325 ++ E + D+ + + K + + V LE D I A L E Sbjct: 645 WLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRH 704 Query: 326 NRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLIEENKEKTR 385 D K + +G +K+ +++A + Y +K P + + + I + R Sbjct: 705 YEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKI-GQLTRAR 763 Query: 386 KNISK 390 + K Sbjct: 764 AILEK 768 >3J98-H nrPDB Length = 297 Score = 31.7 bits (70), Expect = 0.59, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 47/137 (34%), Gaps = 8/137 (5%) Query: 256 YSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYA 315 Y K++ + D + + + K L ++ LE+Y AI Sbjct: 133 YETELVDVEKAIAHYE-----QSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIY 187 Query: 316 TYL--LEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRIEYV 373 + MD+ + AK Y+ + + A +E P + + Sbjct: 188 EQVGTSAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSR-ECKLM 246 Query: 374 NRLIEENKEKTRKNISK 390 +L+E ++E+ + ++ Sbjct: 247 KKLLEAHEEQNVDSYTE 263 >6FUZ-A nrPDB Length = 337 Score = 31.3 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 39/111 (35%), Gaps = 12/111 (10%) Query: 262 KYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEM 321 KY+ + N +N+ + + R+ + + NL+++ +Y +A LE+ Sbjct: 70 KYKDAANLLNDALAIREKTLGRDHPAVAATLN---NLAVLYGKRGKYKEAEPLCKRALEI 126 Query: 322 DN----VPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCK-----EKNPDD 363 + D AK + + +E Y + PDD Sbjct: 127 REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDD 177 >6C95-A nrPDB Length = 866 Score = 30.9 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 23/132 (17%), Positives = 50/132 (37%), Gaps = 27/132 (20%) Query: 253 KKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAI 312 K Y A YR +L + + N+Q + +LSL+ + + Sbjct: 93 DKKYDEAIKCYRNALKW-----------DKDNLQILR-------DLSLLQIQMRDLEGYR 134 Query: 313 MYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEA---LQDYIFCKEKNPD--DEVIE 367 LL++ Q ++ +Y + + A L+++ ++ +PD D Sbjct: 135 ETRYQLLQL----RPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYS 190 Query: 368 QRIEYVNRLIEE 379 + + Y N+++ E Sbjct: 191 ELLLYQNQVLRE 202 >2VL7-A nrPDB Length = 540 Score = 30.5 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 60/158 (37%), Gaps = 16/158 (10%) Query: 229 GDDDFGKALEAANIIKESGTLLFKKKDYSNAFFKYRKSLNYINEYMPEPDVDKERNIQFI 288 GD++ + + +K+ + + K+ S +++ +++Y Y ++ + I Sbjct: 93 GDEEPDEINCSKCRLKDKIKTI-EDKEPSKLIEEFKDAVDYCPYYSLRANLKDKDVIAMT 151 Query: 289 -------NLKMKIYLNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAKAYYRRGNSYL 341 ++ ++ N LE Y I A LLE D R ++ R + Sbjct: 152 YPYLFQKPIRNSVFCNKDDC-LKLEDYLIVIDEAHNLLEADKWFTRKISRKMLERALKEI 210 Query: 342 KKKRLDEALQDYIFCKEKNPDDEVIEQRIEYVNRLIEE 379 + D K+ I I+Y+++LI++ Sbjct: 211 EIVE-RLNRIDAKKVKDY------INLLIDYMSKLIKD 241 >2DE0-X nrPDB Length = 526 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 30/95 (31%), Gaps = 5/95 (5%) Query: 41 CAGDVKSPLKDQQYLSYKGNGFHRVVKNFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADK 100 C+ K + Y G H VV FMI G + + G +++ Sbjct: 142 CSKAKKLVCNINKGCGY-GCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPV 200 Query: 101 EEVKTD----DESFCYGNFEDENLGEFVEPFTLGM 131 E TD G +D+N+ P + Sbjct: 201 SETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSL 235 >2YXX-A nrPDB Length = 386 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 24/85 (28%), Gaps = 17/85 (20%) Query: 167 GKSVVRTIENCRVDSDGVPESDVRISDCGVWEKTMGVPLYNASNDQIGGDVYEEYPDDDT 226 G VV E GVP V S DQ+ E + +D Sbjct: 63 GMDVVTKGELLAAKLAGVPSHTVV------------WNGNGKSRDQM-----EHFLREDV 105 Query: 227 HFGDDDFGKALEAANIIKESGTLLF 251 + D + +E + G F Sbjct: 106 RIVNVDSFEEMEIWRELNPEGVEYF 130 >1W55-A nrPDB Length = 371 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 26/64 (40%), Gaps = 12/64 (18%) Query: 210 NDQIGGDVYEEYPDDDTHFGDDDFGKALEAA-NIIKESGTLLF-----------KKKDYS 257 GD+ E YPD D F + + + L+ A + ++E G L K KD+ Sbjct: 259 GAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREIGFELINIDICVMAQSPKLKDFK 318 Query: 258 NAFF 261 A Sbjct: 319 QAMQ 322 >6EQI-C nrPDB Length = 433 Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 46/110 (41%), Gaps = 10/110 (9%) Query: 257 SNAFFK--YRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMY 314 S A K YR+++ ++ + + NI +++ + N+ + + D I Sbjct: 62 STAILKAMYRETVPAMSYFFNQNLF-NIENISDFKIRLPPHPNIVRMY---SVFADRIPD 117 Query: 315 --ATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPD 362 L + +P R + R + +L KR D L++Y ++K P+ Sbjct: 118 LQCNKQLYPEALPPRINPEGSGRNMSLFLVMKRYDCTLKEY--LRDKTPN 165 >3NUM-A nrPDB Length = 332 Score = 29.4 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 25/47 (53%) Query: 146 ITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRIS 192 +T+ A L +H F V+ G ++ I + ++ G+ E+DV IS Sbjct: 234 LTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIIS 280 >3J8B-L nrPDB Length = 540 Score = 29.4 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 34/93 (36%), Gaps = 6/93 (6%) Query: 302 LFNLERYDDAIMYATYLLEMDNVPNRD-----QAKAYYRRGNSYLKKKRLDEALQDYIFC 356 L Y AI +E++ Q YY G +YL +R +A++ + Sbjct: 281 HSLLGDYYQAIK-VLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANI 339 Query: 357 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNIS 389 + + QR Y +I + E+ ++ Sbjct: 340 LLYIQRTKSMFQRTTYKYEMINKQNEQMHALLA 372 >5A5T-L nrPDB Length = 564 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 34/93 (36%), Gaps = 6/93 (6%) Query: 302 LFNLERYDDAIMYATYLLEMDNVPNRD-----QAKAYYRRGNSYLKKKRLDEALQDYIFC 356 L Y AI +E++ Q YY G +YL +R +A++ + Sbjct: 281 HSLLGDYYQAIK-VLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANI 339 Query: 357 KEKNPDDEVIEQRIEYVNRLIEENKEKTRKNIS 389 + + QR Y +I + E+ ++ Sbjct: 340 LLYIQRTKSMFQRTTYKYEMINKQNEQMHALLA 372 >5OJF-A nrPDB Length = 314 Score = 28.6 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 39/111 (35%), Gaps = 12/111 (10%) Query: 262 KYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEM 321 KY+ + + +N+ + + ++ + + NL+++ +Y +A LE+ Sbjct: 85 KYKDAAHLLNDALAIREKTLGKDHPAVAATLN---NLAVLYGKRGKYKEAEPLCKRALEI 141 Query: 322 DNVP----NRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN-----PDD 363 + D AK + + +E Y E PDD Sbjct: 142 REKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDD 192 >3ZFW-A nrPDB Length = 263 Score = 28.6 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 39/111 (35%), Gaps = 12/111 (10%) Query: 262 KYRKSLNYINEYMPEPDVDKERNIQFINLKMKIYLNLSLVLFNLERYDDAIMYATYLLEM 321 KY+ + + +N+ + + ++ + + NL+++ +Y +A LE+ Sbjct: 38 KYKDAAHLLNDALAIREKTLGKDHPAVAATLN---NLAVLYGKRGKYKEAEPLCKRALEI 94 Query: 322 DNVP----NRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKN-----PDD 363 + D AK + + +E Y E PDD Sbjct: 95 REKVLGKFHPDVAKQLSNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDD 145 >1F7U-A nrPDB Length = 607 Score = 28.2 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 53/156 (33%), Gaps = 18/156 (11%) Query: 186 ESDVRISDCGVWEKTM--GVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAANII 243 + DV + V +++M + L+ G +E+ F K L A + Sbjct: 287 KYDVYSGESQVSKESMLKAIDLFKEK-----GLTHEDKGAVLIDL--TKFNKKLGKAIVQ 339 Query: 244 KESGTLLFKKKDYSNAFFKYRK--------SLNYINEYMPEPDVDKERNIQFINLKMKIY 295 K GT L+ +D A +Y K + + + + + F K + Sbjct: 340 KSDGTTLYLTRDVGAAMDRYEKYHFDKMIYVIASQQDLHAAQFFEILKQMGFEWAKDLQH 399 Query: 296 LNLSLVLFNLERYDDAIMYATYLLEMDNVPNRDQAK 331 +N +V + +++ +LE + K Sbjct: 400 VNFGMVQ-GMSTRKGTVVFLDNILEETKEKMHEVMK 434 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.126 0.345 Lambda K H 0.267 0.0385 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,094,126 Number of Sequences: 36641 Number of extensions: 626816 Number of successful extensions: 2259 Number of sequences better than 10.0: 118 Number of HSP's better than 10.0 without gapping: 165 Number of HSP's successfully gapped in prelim test: 44 Number of HSP's that attempted gapping in prelim test: 1641 Number of HSP's gapped (non-prelim): 246 length of query: 393 length of database: 10,336,785 effective HSP length: 99 effective length of query: 294 effective length of database: 6,709,326 effective search space: 1972541844 effective search space used: 1972541844 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)