BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46926 (289 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1NE7-A nrPDB 605 e-173 5HJ5-A nrPDB 342 9e-95 1FS5-A nrPDB 334 2e-92 3HN6-A nrPDB 328 2e-90 2BKX-A nrPDB 183 6e-47 2RI0-A nrPDB 132 2e-31 6NBG-A nrPDB 91 6e-19 1VL1-A nrPDB 46 2e-05 3ICO-A nrPDB 44 6e-05 3EB9-A nrPDB 42 2e-04 3TX2-A nrPDB 39 0.003 1Y89-A nrPDB 35 0.030 5ZWN-y nrPDB 29 2.4 4W7S-A nrPDB 29 2.7 4F40-A nrPDB 28 3.5 2CJK-A nrPDB 28 4.3 5AB6-A nrPDB 28 5.3 >1NE7-A nrPDB Length = 289 Score = 605 bits (1559), Expect = e-173, Method: Compositional matrix adjust. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD Sbjct: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA Sbjct: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK Sbjct: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD Sbjct: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 Query: 241 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 289 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD Sbjct: 241 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 289 >5HJ5-A nrPDB Length = 267 Score = 342 bits (878), Expect = 9e-95, Method: Compositional matrix adjust. Identities = 161/258 (62%), Positives = 199/258 (77%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 M+LI L+ +Q +WAA +I RI +F P E+ F LGLPTG TPL YK LIE +K G+ Sbjct: 1 MRLIPLKAAAQVGKWAAAHIVKRINEFQPTAERPFVLGLPTGGTPLATYKALIEMHKAGE 60 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 +SFK+V TFNMDEYVGL DHPESY SFM+NNFF HIDI EN ++L+GN D +AEC Sbjct: 61 VSFKHVVTFNMDEYVGLAADHPESYRSFMYNNFFNHIDIQEENINLLNGNTDDHEAECKR 120 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +E+KIK+ G I LF+GG+G DGHIAFNEP SSL SRTR+KTL DT +AN+RFFDG++ + Sbjct: 121 YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQ 180 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALT+GVGT++DA+E+MIL+TG +KA AL A+E VNH+WTVSA Q HP+ V VCD Sbjct: 181 VPKYALTIGVGTLLDAQEIMILVTGHNKALALQAAVEGSVNHLWTVSALQLHPKAVIVCD 240 Query: 241 EDATLELKVKTVKYFKGL 258 E +T ELKVKTVKYF L Sbjct: 241 EPSTQELKVKTVKYFTEL 258 >1FS5-A nrPDB Length = 266 Score = 334 bits (857), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 154/258 (59%), Positives = 196/258 (75%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 M+LI L Q +WAA++I NRI F P ++ F LGLPTG TP+ YK L+E +K G Sbjct: 1 MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQ 60 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 +SFK+V TFNMDEYVGLP++HPESY+SFM NFF H+DI EN ++L+GNA D+ AEC Sbjct: 61 VSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQ 120 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +EEKI++ G I LF+GG+G DGHIAFNEP SSL SRTR+KTL DT +AN+RFFD ++ + Sbjct: 121 YEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQ 180 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALTVGVGT++DA EVMIL+ G+ KA AL A+E VNHMWT+S Q HP+ + VCD Sbjct: 181 VPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCD 240 Query: 241 EDATLELKVKTVKYFKGL 258 E +T+ELKVKT++YF L Sbjct: 241 EPSTMELKVKTLRYFNEL 258 >3HN6-A nrPDB Length = 289 Score = 328 bits (841), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 159/258 (61%), Positives = 202/258 (78%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 M+LII Y S+WAA ++ +I +F+P E F LGLPTGS+P+G YK LIE KN Sbjct: 22 MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKK 81 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 +SF+ V TFNMDEY+G+ +HPESYHSFMWNNFF HIDI EN +IL+GNA +L+ EC+ Sbjct: 82 ISFQNVITFNMDEYIGIEENHPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEE 141 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +E+KIK+ GGI LFVGGIGPDGHIAFNEPGSSL SRTR+KTL DTI+AN+RFF+G++ K Sbjct: 142 YEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGDVNK 201 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALTVG+GT+MD++EV+I++ G +KA AL AIE+GVNHMWT+SA Q H + V D Sbjct: 202 VPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD 261 Query: 241 EDATLELKVKTVKYFKGL 258 ++AT ELKV TV+YF + Sbjct: 262 KNATYELKVGTVEYFNDI 279 >2BKX-A nrPDB Length = 242 Score = 183 bits (465), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 96/243 (39%), Positives = 146/243 (60%), Gaps = 6/243 (2%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MK++ + Y + S+ AA+ + I + P+ LGL TG TP G Y++LI ++ + Sbjct: 1 MKVMECQTYEELSQIAARITADTIKE---KPDA--VLGLATGGTPEGTYRQLIRLHQTEN 55 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 LSF+ + T N+DEY GL D P SYH +M + FF+HID P I +GNA DL+AEC Sbjct: 56 LSFQNITTVNLDEYAGLSSDDPNSYHFYMNDRFFQHIDSKPSRHFIPNGNADDLEAECRR 115 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +E+ + + G ++ + GIG +GHI FNEPG+S SRT V TL T ANAR+F + Sbjct: 116 YEQLVDSLGDTDIQLLGIGRNGHIGFNEPGTSFKSRTHVVTLNEQTRQANARYFPS-IDS 174 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALT+G+ T++ ++ +++LI+G KA A+ K +E ++ + SA H + D Sbjct: 175 VPKKALTMGIQTILSSKRILLLISGKSKAEAVRKLLEGNISEDFPASALHLHSDVTVLID 234 Query: 241 EDA 243 +A Sbjct: 235 REA 237 >2RI0-A nrPDB Length = 234 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 83/243 (34%), Positives = 134/243 (55%), Gaps = 14/243 (5%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MK I +++ ++ S+ A + + I F TLGL TGSTPL YK++ E + Sbjct: 2 MKTIKVKNKTEGSKVAFRMLEEEIT-FGAK-----TLGLATGSTPLELYKEIRESH---- 51 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 L F + + N+DEYVGL D +SY FM N F + +++ +G A DL E + Sbjct: 52 LDFSDMVSINLDEYVGLSADDKQSYAYFMKQNLFAAKPF--KKSYLPNGLAADLAKETEY 109 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +++ I A I+L + GIG + HI FNEPG++ S+T + L TI AN+RFF+ + Sbjct: 110 YDQ-ILAQYPIDLQILGIGRNAHIGFNEPGTAFSSQTHLVDLTPSTIAANSRFFE-KAED 167 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP A+++G+ ++M A+ ++++ G KA A+ ++ V S Q HP+ + + D Sbjct: 168 VPKQAISMGLASIMSAKMILLMAFGEEKAEAVAAMVKGPVTEEIPASILQTHPKVILIVD 227 Query: 241 EDA 243 E A Sbjct: 228 EKA 230 >6NBG-A nrPDB Length = 242 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 73/251 (29%), Positives = 120/251 (47%), Gaps = 16/251 (6%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MK+I+ E Y + S A+ ++ I P + L + GSTP Y+ L K G Sbjct: 4 MKMIVTEDYEEMSLVASHHVLGYIT----APRR-VNLAVTAGSTPKRMYEHLTAAVK-GK 57 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 + V +N DE + S + FF I EN H L +D A+ D Sbjct: 58 AFYDRVHYYNFDEIPFRGQSREGVTISNLRQLFFTPAQIKEENIHKL---TLDNAAQHD- 113 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTL---AMDTILANARFFDGE 177 +++ AGG++L V G+G DGH N P ++ V+ M ++AN+ G+ Sbjct: 114 --RQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIANSEM-GGD 170 Query: 178 LTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVF 237 ++ VP +T+G +VM A+ ++++++GA KA AL + +E V+ S + HP V Sbjct: 171 ISAVPNSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVI 230 Query: 238 VCDEDATLELK 248 + D+ A EL+ Sbjct: 231 IADKAAAAELQ 241 >1VL1-A nrPDB Length = 232 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 36/133 (27%), Positives = 64/133 (48%), Gaps = 8/133 (6%) Query: 14 EWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDE 73 ++ + IR ++ + +K F + L G TPL Y+KL E + + F DE Sbjct: 27 DFVVEKIRTKMEKLLEEKDKIFVV-LAGGRTPLPVYEKLAEQ----KFPWNRIHFFLSDE 81 Query: 74 YVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGG-IE 132 +P D +S + F I N H +D ++ ++ C+ +E +I++A + Sbjct: 82 RY-VPLDSDQSNFRNINEVLFSRAKIPSGNVHYVD-TSLPIEKACEKYEREIRSATDQFD 139 Query: 133 LFVGGIGPDGHIA 145 L + G+GPDGH+A Sbjct: 140 LAILGMGPDGHVA 152 >3ICO-A nrPDB Length = 268 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 54/214 (25%), Positives = 86/214 (40%), Gaps = 33/214 (15%) Query: 46 LGCYKKLIEYYKNGDLSFKYVKTFNMDE-YVGLPRDHPESYHSFMWNNFFKHIDIHPENT 104 L + IE+ K V F DE YV P D E H+DI Sbjct: 74 LSAQAQQIEWSK--------VHLFWGDERYV--PEDDDERNLKQARRALLNHVDIPSNQV 123 Query: 105 HIL---DGN-AVDLQAECDAFEEKIKAAGG-------IELFVGGIGPDGHIAFNEPGSSL 153 H + DG+ DL A A+E+ + A+ ++ + G+GP+GHI P S Sbjct: 124 HPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHINSLFPHSPA 183 Query: 154 VSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALY 213 V + +A+D + K P +T+ + + +REV +L++G KA A+ Sbjct: 184 VLESTRMVVAVD-----------DSPKPPPRRITLTLPAIQRSREVWLLVSGPGKADAVA 232 Query: 214 KAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLEL 247 AI + T+++ D DA +L Sbjct: 233 AAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKL 266 >3EB9-A nrPDB Length = 266 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 55/211 (26%), Positives = 88/211 (41%), Gaps = 32/211 (15%) Query: 24 IIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPE 83 II+ + + ++ L GSTP Y +L + + N + ++ F DE + +P D + Sbjct: 27 IIEASGSQQWPLSIALAGGSTPKMTYARLHDEHLNLLREKRALRFFMGDERM-VPADSTD 85 Query: 84 SYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEE-KIKAAGGIELF-------V 135 S ++ M H DI + D +AV AE + + ++ A G +L V Sbjct: 86 SNYN-MAREVLLH-DIPDDLVFPFDTSAVTPSAEATSADAMRVAEAYGKQLASLLPLKSV 143 Query: 136 G--------------GIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKV 181 G G+G DGH A PGS T K + + F E K Sbjct: 144 GEAGPKVPVFDVVLLGLGSDGHTASIFPGSQAEKETDGKVVV-------SVGFPSETMKP 196 Query: 182 PTMALTVGVGTVMDAREVMILITGAHKAFAL 212 +T+ T+M AR V++L TGA K + + Sbjct: 197 KVWRVTLSPATIMQARNVIVLATGAEKKWVV 227 >3TX2-A nrPDB Length = 251 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 50/220 (22%), Positives = 90/220 (40%), Gaps = 25/220 (11%) Query: 39 LPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHID 98 L G T + K L + D + +V + D YV P+ PE W +H++ Sbjct: 45 LTGGGTGIALLKHLRDVASGLDWTNVHV-FWGDDRYV--PKTDPERNAWQAWEALLEHVN 101 Query: 99 IHPENTHILDGN----AVDLQAECDAFEEKIKAAG-------GIELFVGGIGPDGHIAFN 147 N H + + DL A A+E+ + A ++ + G+G +GHI Sbjct: 102 FPLRNMHAMPNSESEYGTDLDAAALAYEQLLAANAEPGQDCPAFDVHLLGMGGEGHINSL 161 Query: 148 EPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAH 207 P + V T+ +A+ + K P +T+ + + +REV ++++G Sbjct: 162 FPHTDAVKETQRLVVAVP-----------DSPKPPPQRITLTLPAIQRSREVWLVVSGEA 210 Query: 208 KAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLEL 247 KA A+ A+ + + RTV++ DE A +L Sbjct: 211 KADAVAAAVGGADPVDVPAAGAKGIERTVWLLDEAAASQL 250 >1Y89-A nrPDB Length = 238 Score = 35.4 bits (80), Expect = 0.030, Method: Compositional matrix adjust. Identities = 37/133 (27%), Positives = 55/133 (41%), Gaps = 7/133 (5%) Query: 37 LGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKH 96 + L GSTP +K L D+ +K + + DE P D ES + F Sbjct: 33 ISLSGGSTPKMLFKLLASQPYANDIQWKNLHFWWGDERCVAPDD-AESNYGEANALLFSK 91 Query: 97 IDIHPENTH-ILDGNAVDLQAE--CDAFEEKIKAAGGIELF---VGGIGPDGHIAFNEPG 150 I++ +N H IL N +AE A I G +F + G+G DGH A PG Sbjct: 92 INMPAQNIHRILGENEPQAEAERFAQAMAHVIPTENGTPVFDWILLGVGADGHTASLFPG 151 Query: 151 SSLVSRTRVKTLA 163 + + + +A Sbjct: 152 QTDYADANLSVVA 164 >5ZWN-y nrPDB Length = 588 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 34 YFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVK 67 Y T+G+ TGS PL ++++EY N + FK +K Sbjct: 398 YATIGVETGSEPL--IQQVVEYADNDEDKFKKLK 429 >4W7S-A nrPDB Length = 463 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 34 YFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVK 67 Y T+G+ TGS PL ++++EY N + FK +K Sbjct: 273 YATIGVETGSEPL--IQQVVEYADNDEDKFKKLK 304 >4F40-A nrPDB Length = 288 Score = 28.5 bits (62), Expect = 3.5, Method: Compositional matrix adjust. Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 17/102 (16%) Query: 96 HIDIHPENTHILDGNAVDLQAECDAFEEKIKA---AGGIELFVGGIGPDGHIAFNEPGSS 152 +++HP N N DL+A CDA + K++A G +L I +N+ + Sbjct: 175 QVELHPLN------NQADLRAFCDAKQIKVEAWSPLGQGKLLSNPILSAIGAKYNKTAAQ 228 Query: 153 LVSRTRV--------KTLAMDTILANARFFDGELTKVPTMAL 186 ++ R + K++ + I NA FD EL M++ Sbjct: 229 VILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSI 270 >2CJK-A nrPDB Length = 167 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 4/37 (10%) Query: 105 HILDGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPD 141 HILDG +D + +E+ K ++FVGGIGPD Sbjct: 66 HILDGKVIDPKRAI-PRDEQDKTG---KIFVGGIGPD 98 >5AB6-A nrPDB Length = 425 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 17/30 (56%) Query: 175 DGELTKVPTMALTVGVGTVMDAREVMILIT 204 D +LT VP AL G G + A V ILI+ Sbjct: 394 DRQLTPVPKRALVYGNGGIFSASSVAILIS 423 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1NE7-A nrPDB 464 e-131 1FS5-A nrPDB 398 e-111 5HJ5-A nrPDB 394 e-110 3HN6-A nrPDB 370 e-103 2BKX-A nrPDB 312 2e-85 6NBG-A nrPDB 268 3e-72 2RI0-A nrPDB 267 6e-72 3ICO-A nrPDB 201 2e-52 3EB9-A nrPDB 190 5e-49 1VL1-A nrPDB 155 2e-38 Sequences not found previously or not previously below threshold: 3TX2-A nrPDB 158 2e-39 4TM8-A nrPDB 151 4e-37 3CH7-A nrPDB 114 6e-26 1Y89-A nrPDB 113 9e-26 3LWD-A nrPDB 84 5e-17 3E15-A nrPDB 81 8e-16 3NWP-A nrPDB 78 5e-15 3LHI-A nrPDB 72 3e-13 1TDJ-A nrPDB 32 0.22 3RAW-A nrPDB 32 0.28 3LJ5-A nrPDB 32 0.33 4PMU-A nrPDB 30 1.6 4ONJ-A nrPDB 29 1.8 2WAQ-N nrPDB 29 1.8 2EF5-A nrPDB 29 3.0 2PMZ-N nrPDB 29 3.6 >1NE7-A nrPDB Length = 289 Score = 464 bits (1194), Expect = e-131, Method: Composition-based stats. Identities = 289/289 (100%), Positives = 289/289 (100%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD Sbjct: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA Sbjct: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK Sbjct: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD Sbjct: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 Query: 241 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 289 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD Sbjct: 241 EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD 289 >1FS5-A nrPDB Length = 266 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 154/258 (59%), Positives = 196/258 (75%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 M+LI L Q +WAA++I NRI F P ++ F LGLPTG TP+ YK L+E +K G Sbjct: 1 MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQ 60 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 +SFK+V TFNMDEYVGLP++HPESY+SFM NFF H+DI EN ++L+GNA D+ AEC Sbjct: 61 VSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQ 120 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +EEKI++ G I LF+GG+G DGHIAFNEP SSL SRTR+KTL DT +AN+RFFD ++ + Sbjct: 121 YEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQ 180 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALTVGVGT++DA EVMIL+ G+ KA AL A+E VNHMWT+S Q HP+ + VCD Sbjct: 181 VPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCD 240 Query: 241 EDATLELKVKTVKYFKGL 258 E +T+ELKVKT++YF L Sbjct: 241 EPSTMELKVKTLRYFNEL 258 >5HJ5-A nrPDB Length = 267 Score = 394 bits (1013), Expect = e-110, Method: Composition-based stats. Identities = 161/258 (62%), Positives = 199/258 (77%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 M+LI L+ +Q +WAA +I RI +F P E+ F LGLPTG TPL YK LIE +K G+ Sbjct: 1 MRLIPLKAAAQVGKWAAAHIVKRINEFQPTAERPFVLGLPTGGTPLATYKALIEMHKAGE 60 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 +SFK+V TFNMDEYVGL DHPESY SFM+NNFF HIDI EN ++L+GN D +AEC Sbjct: 61 VSFKHVVTFNMDEYVGLAADHPESYRSFMYNNFFNHIDIQEENINLLNGNTDDHEAECKR 120 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +E+KIK+ G I LF+GG+G DGHIAFNEP SSL SRTR+KTL DT +AN+RFFDG++ + Sbjct: 121 YEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLSSRTRIKTLTEDTRIANSRFFDGDINQ 180 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALT+GVGT++DA+E+MIL+TG +KA AL A+E VNH+WTVSA Q HP+ V VCD Sbjct: 181 VPKYALTIGVGTLLDAQEIMILVTGHNKALALQAAVEGSVNHLWTVSALQLHPKAVIVCD 240 Query: 241 EDATLELKVKTVKYFKGL 258 E +T ELKVKTVKYF L Sbjct: 241 EPSTQELKVKTVKYFTEL 258 >3HN6-A nrPDB Length = 289 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 159/258 (61%), Positives = 202/258 (78%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 M+LII Y S+WAA ++ +I +F+P E F LGLPTGS+P+G YK LIE KN Sbjct: 22 MRLIIRPTYEDISKWAANHVAQKINEFSPTKENPFILGLPTGSSPIGMYKNLIELNKNKK 81 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 +SF+ V TFNMDEY+G+ +HPESYHSFMWNNFF HIDI EN +IL+GNA +L+ EC+ Sbjct: 82 ISFQNVITFNMDEYIGIEENHPESYHSFMWNNFFSHIDIKKENINILNGNASNLKKECEE 141 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +E+KIK+ GGI LFVGGIGPDGHIAFNEPGSSL SRTR+KTL DTI+AN+RFF+G++ K Sbjct: 142 YEKKIKSFGGIMLFVGGIGPDGHIAFNEPGSSLTSRTRIKTLTQDTIIANSRFFEGDVNK 201 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALTVG+GT+MD++EV+I++ G +KA AL AIE+GVNHMWT+SA Q H + V D Sbjct: 202 VPKNALTVGIGTIMDSQEVLIIVNGHNKARALKHAIEKGVNHMWTISALQLHKNAIIVSD 261 Query: 241 EDATLELKVKTVKYFKGL 258 ++AT ELKV TV+YF + Sbjct: 262 KNATYELKVGTVEYFNDI 279 >2BKX-A nrPDB Length = 242 Score = 312 bits (798), Expect = 2e-85, Method: Composition-based stats. Identities = 96/244 (39%), Positives = 146/244 (59%), Gaps = 6/244 (2%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MK++ + Y + S+ AA+ + I + P+ LGL TG TP G Y++LI ++ + Sbjct: 1 MKVMECQTYEELSQIAARITADTIKE---KPDA--VLGLATGGTPEGTYRQLIRLHQTEN 55 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 LSF+ + T N+DEY GL D P SYH +M + FF+HID P I +GNA DL+AEC Sbjct: 56 LSFQNITTVNLDEYAGLSSDDPNSYHFYMNDRFFQHIDSKPSRHFIPNGNADDLEAECRR 115 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +E+ + + G ++ + GIG +GHI FNEPG+S SRT V TL T ANAR+F + Sbjct: 116 YEQLVDSLGDTDIQLLGIGRNGHIGFNEPGTSFKSRTHVVTLNEQTRQANARYFPS-IDS 174 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP ALT+G+ T++ ++ +++LI+G KA A+ K +E ++ + SA H + D Sbjct: 175 VPKKALTMGIQTILSSKRILLLISGKSKAEAVRKLLEGNISEDFPASALHLHSDVTVLID 234 Query: 241 EDAT 244 +A Sbjct: 235 REAA 238 >6NBG-A nrPDB Length = 242 Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 71/251 (28%), Positives = 119/251 (47%), Gaps = 16/251 (6%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MK+I+ E Y + S A+ ++ I + L + GSTP Y+ L K G Sbjct: 4 MKMIVTEDYEEMSLVASHHVLGYIT-----APRRVNLAVTAGSTPKRMYEHLTAAVK-GK 57 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 + V +N DE + S + FF I EN H L +D A+ Sbjct: 58 AFYDRVHYYNFDEIPFRGQSREGVTISNLRQLFFTPAQIKEENIHKL---TLDNAAQH-- 112 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTL---AMDTILANARFFDGE 177 + +++ AGG++L V G+G DGH N P ++ V+ M ++AN+ G+ Sbjct: 113 -DRQLEEAGGLDLMVLGLGADGHFCGNLPNTTRFHDQTVEVPIHGEMIALIANSEM-GGD 170 Query: 178 LTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVF 237 ++ VP +T+G +VM A+ ++++++GA KA AL + +E V+ S + HP V Sbjct: 171 ISAVPNSYVTMGPRSVMAAKNLLLIVSGAAKAHALKQVVEGPVSVQVPASVLKLHPSLVI 230 Query: 238 VCDEDATLELK 248 + D+ A EL+ Sbjct: 231 IADKAAAAELQ 241 >2RI0-A nrPDB Length = 234 Score = 267 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 83/245 (33%), Positives = 133/245 (54%), Gaps = 14/245 (5%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD 60 MK I +++ ++ S+ A + + I F TLGL TGSTPL YK++ E + Sbjct: 2 MKTIKVKNKTEGSKVAFRMLEEEIT-FGAK-----TLGLATGSTPLELYKEIRESH---- 51 Query: 61 LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA 120 L F + + N+DEYVGL D +SY FM N F +++ +G A DL E + Sbjct: 52 LDFSDMVSINLDEYVGLSADDKQSYAYFMKQNLFAAKPFK--KSYLPNGLAADLAKETEY 109 Query: 121 FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK 180 +++ I A I+L + GIG + HI FNEPG++ S+T + L TI AN+RFF+ + Sbjct: 110 YDQ-ILAQYPIDLQILGIGRNAHIGFNEPGTAFSSQTHLVDLTPSTIAANSRFFE-KAED 167 Query: 181 VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD 240 VP A+++G+ ++M A+ ++++ G KA A+ ++ V S Q HP+ + + D Sbjct: 168 VPKQAISMGLASIMSAKMILLMAFGEEKAEAVAAMVKGPVTEEIPASILQTHPKVILIVD 227 Query: 241 EDATL 245 E A Sbjct: 228 EKAGA 232 >3ICO-A nrPDB Length = 268 Score = 201 bits (512), Expect = 2e-52, Method: Composition-based stats. Identities = 51/222 (22%), Positives = 88/222 (39%), Gaps = 25/222 (11%) Query: 37 LGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKH 96 + L G + + L + + + V F DE +P D E H Sbjct: 59 IVLTGGGNGIALLRYLSA--QAQQIEWSKVHLFWGDERY-VPEDDDERNLKQARRALLNH 115 Query: 97 IDIHPENTHIL---DGN-AVDLQAECDAFEEKIKAAGG-------IELFVGGIGPDGHIA 145 +DI H + DG+ DL A A+E+ + A+ ++ + G+GP+GHI Sbjct: 116 VDIPSNQVHPMAASDGDFGGDLDAAALAYEQVLAASAAPGDPAPNFDVHLLGMGPEGHIN 175 Query: 146 FNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITG 205 P S V + +A+D + K P +T+ + + +REV +L++G Sbjct: 176 SLFPHSPAVLESTRMVVAVD-----------DSPKPPPRRITLTLPAIQRSREVWLLVSG 224 Query: 206 AHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLEL 247 KA A+ AI + T+++ D DA +L Sbjct: 225 PGKADAVAAAIGGADPVSVPAAGAVGRQNTLWLLDRDAAAKL 266 >3EB9-A nrPDB Length = 266 Score = 190 bits (483), Expect = 5e-49, Method: Composition-based stats. Identities = 60/264 (22%), Positives = 101/264 (38%), Gaps = 36/264 (13%) Query: 8 HYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVK 67 + S + I II+ + + ++ L GSTP Y +L + + N + ++ Sbjct: 12 TPQELSAAGCRKIVE-IIEASGSQQWPLSIALAGGSTPKMTYARLHDEHLNLLREKRALR 70 Query: 68 TFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEE-KIK 126 F DE + +P D +S + M H DI + D +AV AE + + ++ Sbjct: 71 FFMGDERM-VPADSTDSNY-NMAREVLLH-DIPDDLVFPFDTSAVTPSAEATSADAMRVA 127 Query: 127 AAGG---------------------IELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMD 165 A G ++ + G+G DGH A PGS T K + Sbjct: 128 EAYGKQLASLLPLKSVGEAGPKVPVFDVVLLGLGSDGHTASIFPGSQAEKETDGKVVV-- 185 Query: 166 TILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWT 225 + F E K +T+ T+M AR V++L TGA K + + + H Sbjct: 186 -----SVGFPSETMKPKVWRVTLSPATIMQARNVIVLATGAEKKWVVDGIL-ADTAHKAP 239 Query: 226 VSAFQ--QHPRTVFVCDEDATLEL 247 V+ F F+ D++ L Sbjct: 240 VARFLRGCEGNVSFLLDKEIAENL 263 >3TX2-A nrPDB Length = 251 Score = 158 bits (399), Expect = 2e-39, Method: Composition-based stats. Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 29/261 (11%) Query: 1 MKLIILEHYSQASEW---AAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYK 57 M I+E Y+ A + + I K + L G T + K L + Sbjct: 5 MSETIIEKYADTDALVTAAGDRLASAITGALAERGKAMIV-LTGGGTGIALLKHLRDV-- 61 Query: 58 NGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGN----AVD 113 L + V F D+ +P+ PE W +H++ N H + + D Sbjct: 62 ASGLDWTNVHVFWGDDRY-VPKTDPERNAWQAWEALLEHVNFPLRNMHAMPNSESEYGTD 120 Query: 114 LQAECDAFEEKIKAAG-------GIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDT 166 L A A+E+ + A ++ + G+G +GHI P + V T+ +A+ Sbjct: 121 LDAAALAYEQLLAANAEPGQDCPAFDVHLLGMGGEGHINSLFPHTDAVKETQRLVVAV-- 178 Query: 167 ILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTV 226 + K P +T+ + + +REV ++++G KA A+ A+ Sbjct: 179 ---------PDSPKPPPQRITLTLPAIQRSREVWLVVSGEAKADAVAAAVGGADPVDVPA 229 Query: 227 SAFQQHPRTVFVCDEDATLEL 247 + + RTV++ DE A +L Sbjct: 230 AGAKGIERTVWLLDEAAASQL 250 >1VL1-A nrPDB Length = 232 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 49/229 (21%), Positives = 92/229 (40%), Gaps = 24/229 (10%) Query: 14 EWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDE 73 ++ + IR ++ + +K F + L G TPL Y+KL E + + F DE Sbjct: 27 DFVVEKIRTKMEKLLEEKDKIFVV-LAGGRTPLPVYEKLAEQ----KFPWNRIHFFLSDE 81 Query: 74 YVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGG-IE 132 +P D +S + F I N H +D ++ ++ C+ +E +I++A + Sbjct: 82 RY-VPLDSDQSNFRNINEVLFSRAKIPSGNVHYVD-TSLPIEKACEKYEREIRSATDQFD 139 Query: 133 LFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGT 192 L + G+GPDGH+A ++T D N F +T+ Sbjct: 140 LAILGMGPDGHVASIF---------DLETGNKD----NLVTFTDPSGDPKVPRVTLTFRA 186 Query: 193 VMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDE 241 + + V+ LI G K L + ++ + + +TV+ + Sbjct: 187 LNTSLYVLFLIRGKEKINRLTEILK---DTPLPAYFVRGKEKTVWFVGK 232 >4TM8-A nrPDB Length = 256 Score = 151 bits (380), Expect = 4e-37, Method: Composition-based stats. Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 21/200 (10%) Query: 57 KNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGN----AV 112 ++G++ + V + DE +P+D E HI I P N H + + Sbjct: 69 RSGEIDWSKVHIYWGDER-FVPQDDDERNDKQAREALLDHIGIPPVNVHAMAASDGEFGD 127 Query: 113 DLQAECDAFEEKIKAAG-----GIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTI 167 DL+A + + + A G ++ + G+G +GH+ P + V T + + Sbjct: 128 DLEAAAAGYAQLLSADFDSSVPGFDVHLLGMGGEGHVNSLFPDTDAVRETERLVVGV--- 184 Query: 168 LANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVS 227 + K P +T+ + V ++REV ++++G KA A+ A+ + Sbjct: 185 --------SDSPKPPPRRITLTLPAVQNSREVWLVVSGEAKADAVAAAVGGADPVDIPAA 236 Query: 228 AFQQHPRTVFVCDEDATLEL 247 RTV++ DE A +L Sbjct: 237 GAVGRERTVWLVDEAAAAKL 256 >3CH7-A nrPDB Length = 266 Score = 114 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 53/266 (19%), Positives = 85/266 (31%), Gaps = 41/266 (15%) Query: 5 ILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFK 64 I E+ SQ S +AA+ + I L L GSTP Y++L E L Sbjct: 9 ICENLSQMS-FAAREVILAAIDARVDKSVPVVLALSGGSTPKRLYEELHEKDLAL-LQQH 66 Query: 65 YVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILD------------GNAV 112 V+ DE + L D +S S + D+ + +D G Sbjct: 67 AVQFILGDERL-LSEDDEQSNFSMATKALLR--DVPSSDVISIDRRAALATSKDEKGGLD 123 Query: 113 DLQAECDAFEEKI-------------KAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRV 159 A +E K+ K+ +++ + G G DGH A P S + Sbjct: 124 GAWAVAQDYEVKLLNCLPCKQINGTAKSVPVVDIVLLGFGSDGHTASIFPDSVAATDEEH 183 Query: 160 KTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEG 219 + F +T+ + A+ V++L G K + + + E Sbjct: 184 VV---------SVSFPSPTMSPKVWRVTLSKTVIQYAKHVVVLAAGKDKNWVVRGVLSES 234 Query: 220 VNHMWTVSAF--QQHPRTVFVCDEDA 243 VS F + D A Sbjct: 235 PTDPLPVSRFLRDCRGSVTLLLDPGA 260 >1Y89-A nrPDB Length = 238 Score = 113 bits (282), Expect = 9e-26, Method: Composition-based stats. Identities = 46/245 (18%), Positives = 91/245 (37%), Gaps = 27/245 (11%) Query: 13 SEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMD 72 ++ K + + ++ ++ + + L GSTP +K L D+ +K + + D Sbjct: 10 ADAVVKSLADDMLAYSQQGQ-PVHISLSGGSTPKMLFKLLASQPYANDIQWKNLHFWWGD 68 Query: 73 EYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFEEKIKAAGG-- 130 E P D ES + F I++ +N H + G + QAE + F + + Sbjct: 69 ERCVAP-DDAESNYGEANALLFSKINMPAQNIHRILGEN-EPQAEAERFAQAMAHVIPTE 126 Query: 131 -----IELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMA 185 + + G+G DGH A PG + + + +A + + Sbjct: 127 NGTPVFDWILLGVGADGHTASLFPGQTDYADANLSVVASH-------------PESGQLR 173 Query: 186 LTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPR---TVFVCDED 242 ++ + A+ + L+ GA KA + + A + H T + D D Sbjct: 174 VSKTAKVLQAAKRISYLVLGAGKAEIVEQIHTTP-AEQLPYPAAKIHSTSGVTEWYLDSD 232 Query: 243 ATLEL 247 A ++ Sbjct: 233 AAAKI 237 >3LWD-A nrPDB Length = 226 Score = 84.5 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 42/232 (18%), Positives = 78/232 (33%), Gaps = 19/232 (8%) Query: 6 LEHYSQASEWAAKYIRNRIIQFNPG---PEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLS 62 + + + A+ + + + Q + L + GSTP + L L Sbjct: 3 MNTTQEGRQRLAERLADTVAQALEADLAKRERALLVVSGGSTPKPFFTSLA----AKALP 58 Query: 63 FKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAFE 122 + V DE + D +S + H L + +A + Sbjct: 59 WARVDVTLADER-WVTADDADSNARLVRETLLV-GPAAEACFHPLTTDDDTPEAGVETVA 116 Query: 123 EKIKAA-GGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKV 181 E++++ + G+G DGH A P S T ++T + ++ V Sbjct: 117 ERLESLPWPASAVILGMGGDGHTASLFPDSE-QLATALETTSAAVVV--------HAPSV 167 Query: 182 PTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHP 233 P +T+ + DA ++ ITG K L +A+ + AF P Sbjct: 168 PQARITLSASRLADAGLHVLHITGNDKRRVLAEALAGDDVRQLPIRAFLSQP 219 >3E15-A nrPDB Length = 312 Score = 80.6 bits (197), Expect = 8e-16, Method: Composition-based stats. Identities = 43/240 (17%), Positives = 86/240 (35%), Gaps = 26/240 (10%) Query: 1 MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEK-YFTLGLPTGSTPLGCYKKLIEYYKNG 59 +K + + + ++ +A YI ++I + E + +GL G TP+ YK I K+ Sbjct: 27 VKYLEAKDLTDFNQKSAYYICHQIAEKQLSKEGGHVVIGLSGGKTPIDVYKN-IALVKDI 85 Query: 60 DLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECD 119 + + F +DE DH S ++ + F E + D + ++ D Sbjct: 86 KIDTSKLIFFIIDERYKR-DDHKFSNYNNIKFLFESLKINEKEQLYRPDTSKNIVECVRD 144 Query: 120 AFEE---KIKAAGGIELFVGGIGPDGHIAFNEP------------GSSLVSRTRVKTLAM 164 E+ +K +++ + G+G D HIA P S + + +K Sbjct: 145 YNEKIKNMVKKYTKVDIAILGMGSDFHIASLFPNIFFNIYMNNYQNSYIYDESSIKVANS 204 Query: 165 DTILANA--------RFFDGELTKVPTMALTVGVGTVMDAREVMILITGAHKAFALYKAI 216 + N +F +TV + + +A + L+ K + Sbjct: 205 NDTSDNDNLDLLKEYVYFTTTNNFDVRKRITVSLDLLGNASSKIFLLNSTDKLDLWKNML 264 >3NWP-A nrPDB Length = 233 Score = 77.9 bits (190), Expect = 5e-15, Method: Composition-based stats. Identities = 39/224 (17%), Positives = 80/224 (35%), Gaps = 25/224 (11%) Query: 17 AKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVG 76 A I +++ + K +L + GSTPL ++ L + + V DE Sbjct: 22 ASKIASQLQEAVDARGKA-SLVVSGGSTPLKLFQLL----SMKSIDWSDVYITLADER-W 75 Query: 77 LPRDHPESYHSFMWNNFFKHIDIHPE-----NTHILDGNAVDLQAECDAFEEKIKAAGGI 131 + D S + + ++ + + N D+ AE + + Sbjct: 76 VEADADASNERLVREHLLQNRASNAKFRGLKNMFSTAEAGADMAAESLSNFPR-----PF 130 Query: 132 ELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVG 191 ++ V G+G DGH P S+ + + + A T P +T+ Sbjct: 131 DVVVLGMGNDGHTCSWFPCSAEL---------ENALTTQALCVATNPTTAPHGRITLSKS 181 Query: 192 TVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRT 235 ++++R++ + + G K +A+E H + A +T Sbjct: 182 AILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKT 225 >3LHI-A nrPDB Length = 232 Score = 71.8 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 37/230 (16%), Positives = 79/230 (34%), Gaps = 15/230 (6%) Query: 7 EHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYV 66 E+ ++A++ A + + + L + G +P+ + L + DL +K V Sbjct: 9 ENAAEAAQSLADAVADALQGALDEKGGA-VLAVSGGRSPIAFFNALSQ----KDLDWKNV 63 Query: 67 KTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDAF-EEKI 125 DE + +P +H +S + K+ +++ + + DA + + Sbjct: 64 GITLADERI-VPTNHADSNTGLVREYLLKNKAAAAVWIPMVEDGKTETELHPDAVVDYAL 122 Query: 126 KAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMA 185 K ++ + G+G DGH A P + A P Sbjct: 123 KHYKQPDVLILGMGNDGHTASIFPKAPQFQ-------TAIDGSAGVALVHTTPVTAPHER 175 Query: 186 LTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRT 235 +++ + + V + I G K +A + N + +S H Sbjct: 176 ISMTLDAIAHTGHVFLAIQGEEKKAVFDQAAQGE-NREYPISLVLNHQGV 224 >1TDJ-A nrPDB Length = 514 Score = 32.5 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 4/79 (5%) Query: 203 ITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCDEDATLELKVKTVKYFKGLMLVH 262 +T KA + A S+ + + + V AT ++KV V+ F G +L+H Sbjct: 73 LTEEQKAHGVITASAGNHAQGVAFSSARLGVKALIVM-PTATADIKVDAVRGFGGEVLLH 131 Query: 263 NKLVDPLYSIKEKETEKSQ 281 D K K E SQ Sbjct: 132 GANFD---EAKAKAIELSQ 147 >3RAW-A nrPDB Length = 381 Score = 32.1 bits (71), Expect = 0.28, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 44/118 (37%), Gaps = 10/118 (8%) Query: 53 IEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESY-----HSFMWNNFFKHIDIHPENTHIL 107 I + G +F+++K N Y LP +Y F+ N H D+ PEN + Sbjct: 131 IAFELLGKNTFEFLKENNFQPYP-LPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFV 189 Query: 108 DGNAVDLQAECDAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMD 165 + L E + EEK I + G H E +++V+ + + Sbjct: 190 NSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDH----EHHTTIVATRHYRPPEVI 243 >3LJ5-A nrPDB Length = 725 Score = 31.7 bits (70), Expect = 0.33, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 72/196 (36%), Gaps = 36/196 (18%) Query: 46 LGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHI-----DIH 100 Y+ ++ K+G + +FN D P+ P + + F+H+ D Sbjct: 313 KEVYEGVVRLTKDGQRLRNMIMSFNADIVARTPKKKPFFWPEQIAG--FEHMYDGNDDYP 370 Query: 101 PENTHILDGNAVDLQAECDAFEE------------KIKAAGGIELFVGGIGPD----GHI 144 + D N+ DL + A+ E + + E+ G+ + G + Sbjct: 371 YYLLNRTDENSGDLPTQPLAYYENPEVPQANAYMLEAATSAVKEVATLGVDTEAVNGGQV 430 Query: 145 AFNEPGSSLVSRTRVKTLAMDTILANARFFDG--------ELTKVPTM-ALTVGVGTVMD 195 AF+ L R ++T LA A DG ++ VP +T+ G+ D Sbjct: 431 AFDTVN-QLNMRADLETYVFQDNLATAMRRDGEIYQSIVNDIYDVPRNVTITLEDGSEKD 489 Query: 196 AR---EVMILITGAHK 208 + EV+ L TG + Sbjct: 490 VQLMAEVVDLATGEKQ 505 >4PMU-A nrPDB Length = 356 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 25/135 (18%), Positives = 39/135 (28%), Gaps = 16/135 (11%) Query: 28 NPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGDLSFKYVKTFNMDEYVGLPRDHPESYHS 87 N PE +FT +TP +++ + + + V D SY S Sbjct: 86 NQTPEWFFTTADGRPNTPAQQLERMRAHIAAVAGRYTGKVQAW--DVVNEIIDEDGSYRS 143 Query: 88 FMW-----------NNFFKHID--IHPENTHILDGNAVDLQAECDAFEEKIKAAGGIELF 134 W N F + D NA + +K + Sbjct: 144 TNWVQRVGDGDTVVRNAFAFAQRYAPDAQLYYNDFNAWRPAKR-EGIVRMVKMLQQAGVR 202 Query: 135 VGGIGPDGHIAFNEP 149 + G+G GH N P Sbjct: 203 IDGVGMQGHWGLNYP 217 >4ONJ-A nrPDB Length = 357 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 5/38 (13%) Query: 119 DAFEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSR 156 D E+ I++ GG +L +GG N GS+ VSR Sbjct: 295 DRLEQLIESFGGFDLVIGG-----SPCNNLAGSNRVSR 327 >2WAQ-N nrPDB Length = 66 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 11/41 (26%) Query: 66 VKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHI 106 + N E G D HIDI E H Sbjct: 22 ITRVNAGENPGKVLDDLGVKRYCCRRMLLSHIDIISEVIHY 62 >2EF5-A nrPDB Length = 290 Score = 28.6 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 26/65 (40%) Query: 141 DGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTKVPTMALTVGVGTVMDAREVM 200 D H FN P +S LA+ + L + R + P + VGV ++ + + Sbjct: 118 DAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDPKDVVLVGVRSLDPGEKRL 177 Query: 201 ILITG 205 + G Sbjct: 178 LKEAG 182 >2PMZ-N nrPDB Length = 66 Score = 28.6 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 11/41 (26%) Query: 66 VKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHI 106 + N E G D H+DI E H Sbjct: 22 ITRVNAGENPGKVLDDLGVKRYCCRRMLLSHVDIINEVIHY 62 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.123 0.298 Lambda K H 0.267 0.0383 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,563,791 Number of Sequences: 36641 Number of extensions: 360302 Number of successful extensions: 1105 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1029 Number of HSP's gapped (non-prelim): 54 length of query: 289 length of database: 10,336,785 effective HSP length: 96 effective length of query: 193 effective length of database: 6,819,249 effective search space: 1316115057 effective search space used: 1316115057 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.0 bits) S2: 58 (27.0 bits)