BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46883 (757 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1D6Z-A nrPDB 1501 0.0 1KSI-A nrPDB 283 1e-76 2CG0-A nrPDB 270 2e-72 3NBJ-A nrPDB 235 6e-62 3LOY-A nrPDB 216 2e-56 3PGB-A nrPDB 141 1e-33 3K5T-A nrPDB 140 3e-33 2PNC-A nrPDB 136 3e-32 1US1-A nrPDB 135 9e-32 1RKY-A nrPDB 129 6e-30 4XQ7-A nrPDB 36 0.079 1MVN-A nrPDB 34 0.30 5M1C-A nrPDB 32 1.3 4F10-A nrPDB 31 2.0 1S7D-A nrPDB 30 2.9 3LFI-A nrPDB 29 7.3 2YCH-A nrPDB 29 7.5 2OCZ-A nrPDB 29 8.0 >1D6Z-A nrPDB Length = 727 Score = 1501 bits (3886), Expect = 0.0, Method: Compositional matrix adjust. Identities = 727/727 (100%), Positives = 727/727 (100%) Query: 31 HGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVP 90 HGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVP Sbjct: 1 HGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVP 60 Query: 91 VVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPN 150 VVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPN Sbjct: 61 VVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPN 120 Query: 151 TRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPI 210 TRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPI Sbjct: 121 TRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPI 180 Query: 211 KDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDA 270 KDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDA Sbjct: 181 KDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDA 240 Query: 271 RLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVA 330 RLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVA Sbjct: 241 RLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVA 300 Query: 331 PAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEG 390 PAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEG Sbjct: 301 PAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEG 360 Query: 391 SLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP 450 SLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP Sbjct: 361 SLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP 420 Query: 451 MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTI 510 MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTI Sbjct: 421 MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTI 480 Query: 511 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN 570 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN Sbjct: 481 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN 540 Query: 571 NSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNP 630 NSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNP Sbjct: 541 NSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNP 600 Query: 631 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH 690 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH Sbjct: 601 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH 660 Query: 691 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 750 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL Sbjct: 661 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 720 Query: 751 GALKKDK 757 GALKKDK Sbjct: 721 GALKKDK 727 >1KSI-A nrPDB Length = 642 Score = 283 bits (725), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 193/645 (29%), Positives = 304/645 (47%), Gaps = 30/645 (4%) Query: 124 HPLNALTADEIKQAVEIVKASADFKPN-TRFTEISLLPPDKEAVWAFALENKPVDQPRKA 182 HPL+ LT +E IV+ N F I L P+K+ V + V PRK Sbjct: 3 HPLDPLTKEEFLAVQTIVQNKYPISNNRLAFHYIGLDDPEKDHVLRYETHPTLVSIPRKI 62 Query: 183 DVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLL--DDFASVQNIINNSEEFAAAVK 240 V+ + E +++L+ ++S I + +G +L D+ + + F +VK Sbjct: 63 FVVAIINSQTHEILINLRIRSIVS-DNIHNGYGFPILSVDEQSLAIKLPLKYPPFIDSVK 121 Query: 241 KRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDL 300 KRG+ + +++ + T+G+F G +++ R +++ ++ N + PI + V DL Sbjct: 122 KRGL-NLSEIVCSSFTMGWF----GEEKNVRTVRLDCFMKESTVNIYVRPITGITIVADL 176 Query: 301 EQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQII----EPEGKNYTITGDMIHWR 356 + KIV+ + + VP + +P P Q +P+G + I G + W Sbjct: 177 DLMKIVEYHDRDIEAVPTAENTEYQVSKQSPPFGPKQHSLTSHQPQGPGFQINGHSVSWA 236 Query: 357 NWDFHLSMNSRVGPMISTVTYND--NGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDS 414 NW FH+ + R G +IS + D R+V+Y+G + + VPY DP +YFK + DS Sbjct: 237 NWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVPYQDPTEEFYFKTFFDS 296 Query: 415 GDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMG 474 G++G G T + +D P +A ++ + G P+ + AI VFE+Y ++H E G Sbjct: 297 GEFGFGLSTVSLIPNRDCPPHAQFIDTYVHSANGTPILLKNAICVFEQYGNIMWRHTENG 356 Query: 475 QPNVSTERRE----LVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTM 530 PN S E L+VR I TVGNYD + DW F +G+I +GI +KG K Sbjct: 357 IPNESIEESRTEVNLIVRTIVTVGNYDNVIDWEFKASGSIKPSIALSGILEIKGTNIK-- 414 Query: 531 HDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMD-PVVKPNTAGGPR 589 H + K+D +G L+ N +G H H Y + LD D+DG +NS V+ R Sbjct: 415 HKDEIKEDL-HGKLVSANSIGIYHDHFYIYYLDFDIDGTHNSFEKTSLKTVRIKDGSSKR 473 Query: 590 TSTMQVNQYNIGNEQDAAQKFDPGTIRL-LSNPNKENRMGNPVSYQIIPYAGGTHPVAKG 648 S E DA L + NPN + +GN V Y++IP A HP+ Sbjct: 474 KSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNEVGYRLIP-AIPAHPL--- 529 Query: 649 AQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTD 708 D++ R +F + +WVT Y+ E++ G Y + S D L ++K N + N D Sbjct: 530 --LTEDDYPQIRGAFTNYNVWVTAYNRTEKWAGGLYVDHSRGDDTLAVWTKQNREIVNKD 587 Query: 709 AVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTLGAL 753 V+W G HV E++PIMP L+P NFF+ P L L Sbjct: 588 IVMWHVVGIHHVPAQEDFPIMPLLSTSFELRPTNFFERNPVLKTL 632 >2CG0-A nrPDB Length = 646 Score = 270 bits (689), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 183/637 (28%), Positives = 306/637 (48%), Gaps = 35/637 (5%) Query: 125 PLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKADV 184 P +A EI + I++ + P R + +L P + A ++ D+ + + Sbjct: 9 PFRLASAGEISEVQGILRTAGLLGPEKRIAYLGVLDPARGA------GSEAEDRRFRVFI 62 Query: 185 IMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVL---LDDFASVQNIINNSEEFAAAVKK 241 + G E V + N ++S + A L ++F V+ ++ E + A+ Sbjct: 63 HDVSGARPQEVTVSVTNGTVISAVELDTAATGELPVLEEEFEVVEQLLATDERWLKALAA 122 Query: 242 RGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYL-DVGDGNYWAHPIENLVAVVDL 300 R + D KV PL+ G F+ + ++ R+L+ ++++ D + + WAHP++ LVA VD+ Sbjct: 123 RNL-DVSKVRVAPLSAGVFEYAE--ERGRRILRGLAFVQDFPEDSAWAHPVDGLVAYVDV 179 Query: 301 EQKKIVKIEEGPVVPVPMTARPFDGRDRVAP---AVKPMQIIEPEGKNYTITG-DMIHWR 356 K++ ++ + V PVP + + P KP+ I +PEG ++T+TG + I W Sbjct: 180 VSKEVTRVIDTGVFPVPAEHGNYTDPELTGPLRTTQKPISITQPEGPSFTVTGGNHIEWE 239 Query: 357 NWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGD 416 W + + R G ++ + + D R ++ S+ M+VPYGDP ++ Y D+G+ Sbjct: 240 KWSLDVGFDVREGVVLHNIAFRDGDRLRPIINRASIAEMVVPYGDPSPIRSWQNYFDTGE 299 Query: 417 YGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEM-GQ 475 Y +G + + G D + L+ I+D G P EI I + E G KH ++ Sbjct: 300 YLVGQYANSLELGCDCLGDITYLSPVISDAFGNPREIRNGICMHEEDWGILAKHSDLWSG 359 Query: 476 PNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETA 535 N + R +V+ + +T+GNYDY F W + +GTI +A ATG V + E Sbjct: 360 INYTRRNRRMVISFFTTIGNYDYGFYWYLYLDGTIEFEAKATG------VVFTSAFPEGG 413 Query: 536 KDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKPNTAGGPRTSTMQV 595 D+ + + + HQHI++ RLD+ +DG N + D V + G R + Sbjct: 414 SDNI---SQLAPGLGAPFHQHIFSARLDMAIDGFTNRVEEEDVVRQTMGPGNERGNAFSR 470 Query: 596 NQYNIGNEQDAAQKFDPGTIR--LLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAP 653 + + E +A ++ D T R ++SNP +NR+ PV Y++ + T G+ A Sbjct: 471 KRTVLTRESEAVREADARTGRTWIISNPESKNRLNEPVGYKLHAHNQPTLLADPGSSIA- 529 Query: 654 DEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTDAVVWM 713 R +F K LWVTRY ER+P G + N+ + GL Y + +D D VVW Sbjct: 530 -----RRAAFATKDLWVTRYADDERYPTGDFVNQHSGGAGLPSYIAQDRDIDGQDIVVWH 584 Query: 714 TTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 750 T G TH R E+WPIMP + V L+P FFD +P L Sbjct: 585 TFGLTHFPRVEDWPIMPVDTVGFKLRPEGFFDRSPVL 621 >3NBJ-A nrPDB Length = 692 Score = 235 bits (599), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 180/661 (27%), Positives = 312/661 (47%), Gaps = 62/661 (9%) Query: 124 HPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKAD 183 HPL+ L+ EIK A VK+ K F ++L P ++A + + P+ PR A Sbjct: 23 HPLDPLSTAEIKAATNTVKSYFAGK-KISFNTVTLREPARKAYIQWKEQGGPL-PPRLAY 80 Query: 184 VIMLDGKH--IIEAVVDLQNNKLLSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAAVKK 241 ++L+ + E +VDL + ++ + ++ ++ ++D S + +I N Sbjct: 81 YVILEAGKPGVKEGLVDLASLSVIETRALETVQPILTVEDLCSTEEVIRNDPAVIEQCVL 140 Query: 242 RGI--TDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVG-DGNYWAHPIENLVAVV 298 GI + KV P T+GY D + G + RL + + Y D + ++HP++ +V Sbjct: 141 SGIPANEMHKVYCDPWTIGY-DERWGTGK--RLQQALVYYRSDEDDSQYSHPLD-FCPIV 196 Query: 299 DLEQKKIVKIEEGPVVPVPMTARPFDGRDR--------------VAPAVKPMQIIEPEGK 344 D E+KK++ I+ +P R + P P+ + +PEG Sbjct: 197 DTEEKKVIFID------IPNRRRKVSKHKHANFYPKHMIEKVGAMRPEAPPINVTQPEGV 250 Query: 345 NYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDI 404 ++ +TG+++ W N+ FH+ N R G ++S V+YND+G R + + SL MIVP+G P+ Sbjct: 251 SFKMTGNVMEWSNFKFHIGFNYREGIVLSDVSYNDHGNVRPIFHRISLSEMIVPFGSPEF 310 Query: 405 GWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYA 464 K LD G+YG G +T+P++ G D L+ +D G P+ + A+ + E Sbjct: 311 PHQRKHALDIGEYGAGYMTNPLSLGCDCKGVIHYLDAHFSDRAGDPITVKNAVCIHEEDD 370 Query: 465 GPEYKHQEMGQ---PNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEA 521 G +KH + ++ T +LVV I T N +Y W+F ++G I +D TGI Sbjct: 371 GLLFKHSDFRDNFATSLVTRATKLVVSQIFTAANXEYCLYWVFMQDGAIRLDIRLTGI-- 428 Query: 522 VKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVK 581 + + D+ ++ +GT + N+ HQH+++ R+D +DG+ NS A D Sbjct: 429 ---LNTYILGDD--EEAGPWGTRVYPNVNAHNHQHLFSLRIDPRIDGDGNSAAACDAKSS 483 Query: 582 PNTAGGPRT---STMQVNQYNIGNEQDAAQKFDPGTIRL--LSNPNKEN-RMGNPVSYQI 635 P G P + + +D+ ++ T R + NPNK N G P SY++ Sbjct: 484 PYPLGSPENMYGNAFYSEKTTFKTVKDSLTNYESATGRSWDIFNPNKVNPYSGKPPSYKL 543 Query: 636 IPYAGGTHPVAKG---AQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHD- 691 + +G A+ AP W H ++ V Y +P G + + + D Sbjct: 544 VSTQCPPLLAKEGSLVAKRAP--WASHSVN-------VVPYKDNRLYPSGDHVPQWSGDG 594 Query: 692 -TGLGQYSKD-NESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPT 749 G+ ++ D +E++DNTD + + T G TH E++P+ P E + +L+P +FF E P Sbjct: 595 VRGMREWIGDGSENIDNTDILFFHTFGITHFPAPEDFPLXPAEPITLMLRPRHFFTENPG 654 Query: 750 L 750 L Sbjct: 655 L 655 >3LOY-A nrPDB Length = 633 Score = 216 bits (551), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 179/662 (27%), Positives = 301/662 (45%), Gaps = 67/662 (10%) Query: 124 HPLNALTADEIKQAVEIVKASADFKPNTRFTEISLL-PPDKEAVWAFALEN--KPVDQ-P 179 HP + ++ E++ +++K + F +I L PP K+ + E KP+ Sbjct: 2 HPYDPISDAELQLTSQLIKDATKGPERPHFIQIDRLDPPKKDMIRYLEAERTGKPLPHIS 61 Query: 180 RKADVIMLDGKHIIEAVVDLQNNKLLSWQPI-KDAHGMVLLDDFASVQNIINNSEEFAAA 238 R V G +A+V++ +++ Q K G ++ +D ++ + A Sbjct: 62 RMTYVYYYIGLDFYKALVNVSYGHIITNQKQPKGVIGPLIAEDIQEIEELATTHPIVKAE 121 Query: 239 VKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVG---DGNYWAHPIENLV 295 ++K + +V+ P + +G D K+D L++ YL + N+++ P++ Sbjct: 122 IEKLKLPPHVRVVCDP----WMNGTDS-KEDRMLIQCYMYLASAAHPESNHYSLPLK-FS 175 Query: 296 AVVDLEQKKIVKIEEGPVVP------------VPMTARPFDGRDRVAPAVKPMQIIEPEG 343 V + KK V+++ P P D +KP+ + +PEG Sbjct: 176 PVFECLTKKFVRMDYLPGGADETVTETQAWDEFPFVEYHPDLNGETIVPLKPLIVQQPEG 235 Query: 344 KNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPD 403 ++ + G I W+ W+F + R G I Y+ + R V+Y SL M VPYGDP Sbjct: 236 PSFNVDGHKISWQGWEFFVIPTVREGFAI----YDIHFKGRSVVYRLSLSEMTVPYGDPR 291 Query: 404 IGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERY 463 ++ K D GD G G + +A G D ++ + G + IP + + E+ Sbjct: 292 APFHRKQAFDLGDCGFGATGNSLALGCDCLGVIKYMDCRRVNTNGDSVLIPNTVCLHEQD 351 Query: 464 AGPEYKHQEMGQPNVST--ERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEA 521 G YKH + NV RRE VV+ I+TV NY+Y+ + IF + G I I ATGI + Sbjct: 352 GGLLYKHTNY-RTNVPVIARRREFVVQTIATVANYEYMLNIIFDQAGEIRIHVRATGILS 410 Query: 522 VKGVKAKTMHDETAKDDTR-YGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVV 580 + KD T +GT + ++ HQH+ +FR+D VDG N++V D V+ Sbjct: 411 TMPLD---------KDVTVPWGTNVGPRVMAAYHQHMLSFRIDPAVDGYENTVV-FDDVI 460 Query: 581 KPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRL---------LSNPNKENRMGN-P 630 + ++N YN+G + PG + + N NK N + P Sbjct: 461 R-------MEKNTKLNPYNVGFVTERTVVEKPGYVEQSPFTNRSYKIINENKINPISKKP 513 Query: 631 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH 690 V+Y+I+ P + D + R F +Q+WVT+Y E + G++ N+S Sbjct: 514 VAYKIM------MPARQMLLADEDSYNNKRAQFATQQVWVTKYRDNELYAAGEFTNQSQT 567 Query: 691 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 750 DTGLG +++ +E++ N + VVW T G TH+ R E++P+MP E L P+ FFD+ P L Sbjct: 568 DTGLGVWARRDENVRNDNPVVWATLGFTHIPRVEDFPVMPVEAHEIALVPFGFFDKNPAL 627 Query: 751 GA 752 Sbjct: 628 SV 629 >3PGB-A nrPDB Length = 797 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 122/451 (27%), Positives = 201/451 (44%), Gaps = 45/451 (9%) Query: 309 EEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGD--MIHWRNWDFHLSMNS 366 + GPV P +DR P V +I P+G Y++ + + W ++ F+++ N Sbjct: 315 QRGPVPP----------QDRKQPPV----MIAPDGARYSVDAERKYVTWMDFSFYIAFNR 360 Query: 367 RVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPI 426 G + + Y ++V+YE L + Y D AYLDS YG G + Sbjct: 361 DTGLSLFDIKYK----GQRVLYELGLQEALAHYAANDPVQSSVAYLDSY-YGFGPYAFEL 415 Query: 427 ARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELV 486 +G D PS A LN + + ++ +FE A + T+ Sbjct: 416 LKGYDCPSYASYLNTSFYKDEETHTHV-DSLCLFEFDADYPMARHSTSEFVSVTKNVYFT 474 Query: 487 VRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLID 546 +R +ST+GNYDY+F + FH +GTIG++ A+G + ++ +G I Sbjct: 475 LRSVSTIGNYDYMFSYNFHMDGTIGVEVRASGY----------IQSAYYANNQDFGYQIH 524 Query: 547 HNIVGTTHQHIYNFRLDLDVDGENNS--LVAMDPVVKPNTAGGPRT-STMQVNQYNIGNE 603 ++ G+ H H+ NF+ D D+ G NN+ LV++ PV K + G +T +TMQ+ + I +E Sbjct: 525 DSLSGSMHDHVLNFKADFDILGPNNTIELVSVVPVTKQFSWSGNKTRNTMQLGRSFIHSE 584 Query: 604 QDAAQK--FDPGTIRLLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRL 661 +A F+ T + N +K N+ G P Y+I+P AG H + + H Sbjct: 585 DEARLNWGFNGQTQLHVVNQDKPNKFGEPRGYRILPSAGTAHLTVLNSSN-----LVHAA 639 Query: 662 SFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDN-ESLDNTDAVVWMTTGTTHV 720 + + + VTR H E Y ++ H+ + + N ESL+ TD VVW+ G HV Sbjct: 640 HWAEYDVQVTRQHDFEPTSAHPYNSQDIHNPPVDFSTFFNGESLNQTDLVVWLNLGMHHV 699 Query: 721 ARAEEWP--IMPTEWVHTLLKPWNFFDETPT 749 + P + T P N+ P+ Sbjct: 700 PHTGDLPNTVFTTAHSGVAFTPLNYLPGDPS 730 >3K5T-A nrPDB Length = 731 Score = 140 bits (352), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 124/431 (28%), Positives = 197/431 (45%), Gaps = 36/431 (8%) Query: 337 QIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMI 396 ++++P G + + G+ + + W F + S G + V + ++ YE S+ + Sbjct: 281 RLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGE----RIAYEVSVQEAV 336 Query: 397 VPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRA 456 YG YLD G +G+G++T +A G D P A L+ P+ PRA Sbjct: 337 ALYGGHTPAGMQTKYLDVG-WGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRA 395 Query: 457 IAVFERYAG-PEYKH---QEMGQPNV--STERRELVVRWISTVGNYDYIFDWIFHENGTI 510 + +FE G P +H G N + + LV+R STV NYDYI+D+IF+ NG + Sbjct: 396 LCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVM 455 Query: 511 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN 570 ATG V A E R+GT + +++G H H+ ++R+DLDV G Sbjct: 456 EAKMHATGY-----VHATFYTPE----GLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTK 506 Query: 571 NSLVAMDPVVKPNT-AGGPRTSTMQ--VNQYNIGNEQDAAQKFDPGTIR-LLSNPNKENR 626 NS + ++ T PR +Q + Q E+ AA +F + LL +EN Sbjct: 507 NSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENP 566 Query: 627 MGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHR-LSFMDKQLWVTRYHPGERFPEGKYP 685 G+ SY++ H +A Q P W + +++ L VT+Y E Y Sbjct: 567 WGHKRSYRL-----QIHSMAD--QVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYH 619 Query: 686 NRSTHD--TGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTEWVHTLLKPW 741 D Q+ +NE+++N D V W+T G H+ +E+ P P V LL+P+ Sbjct: 620 QNDPWDPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPF 679 Query: 742 NFFDETPTLGA 752 NFF E P+L + Sbjct: 680 NFFPEDPSLAS 690 >2PNC-A nrPDB Length = 746 Score = 136 bits (343), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 117/438 (26%), Positives = 194/438 (44%), Gaps = 36/438 (8%) Query: 326 RDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRK 385 + +V P P P+G +++ G+ + W F + + GP + V + + Sbjct: 286 KSQVPPGPTPPLQFHPQGPRFSVQGNRVASSLWTFSFGLGAFSGPRVFDVRFQGE----R 341 Query: 386 VMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIAD 445 + YE SL YG Y+DSG +GMG +P+ RG D P A ++ Sbjct: 342 LAYEISLQEAGAVYGGNTPAAMLTRYMDSG-FGMGYFATPLIRGVDCPYLATYMDWHFVV 400 Query: 446 YTGVPMEIPRAIAVFERYAG-PEYKHQE--MGQPNVSTERRELVVRWISTVGNYDYIFDW 502 + P + A VFE+ G P +H + + LV R +ST+ NYDY++D Sbjct: 401 ESQTPKTLHDAFCVFEQNKGLPLRRHHSDFLSHYFGGVAQTVLVFRSVSTMLNYDYVWDM 460 Query: 503 IFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRL 562 +F+ NG I + ATG + + RYG + + +G H H ++++ Sbjct: 461 VFYPNGAIEVKLHATGYISSAFLFGAA---------RRYGNQVGEHTLGPVHTHSAHYKV 511 Query: 563 DLDVDGENNSLVAMDPVVKPNT---AGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLS 619 DLDV G N + A D P + + +QV + + E+ AA + R L Sbjct: 512 DLDVGGLENWVWAEDMAFVPTAIPWSPEHQIQRLQVTRKQLETEEQAAFPLGGASPRYLY 571 Query: 620 NPNKE-NRMGNPVSYQI--IPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPG 676 +K+ N+ G+P Y+I + +AGG P Q +P E S+ QL +T+ Sbjct: 572 LASKQSNKWGHPRGYRIQTVSFAGGPMP-----QNSPME---RAFSWGRYQLAITQRKET 623 Query: 677 ERFPEGKYPNRSTHDTGLGQYSK--DNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTE 732 E + N++ T +S +NE++ D V W+T G H+ AE+ P + Sbjct: 624 EPSSSSVF-NQNDPWTPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGN 682 Query: 733 WVHTLLKPWNFFDETPTL 750 V L+P+NFFD+ P++ Sbjct: 683 GVGFFLRPYNFFDQEPSM 700 >1US1-A nrPDB Length = 763 Score = 135 bits (339), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 120/421 (28%), Positives = 187/421 (44%), Gaps = 32/421 (7%) Query: 341 PEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYG 400 P+G +++ G + W F + + GP I V + +++YE SL + YG Sbjct: 318 PQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFDVRFQGE----RLVYEISLQEALAIYG 373 Query: 401 DPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVF 460 Y+D G +GMG T+P+ RG D P A ++ + P I A VF Sbjct: 374 GNSPAAMTTRYVDGG-FGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVF 432 Query: 461 ERYAG-PEYKHQEMGQPNVSTERRE--LVVRWISTVGNYDYIFDWIFHENGTIGIDAGAT 517 E+ G P +H + E LVVR +ST+ NYDY++D +FH +G I I AT Sbjct: 433 EQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMSTLLNYDYVWDTVFHPSGAIEIRFYAT 492 Query: 518 GIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMD 577 G + + + T K YG + + +GT H H +F++DLDV G N + A D Sbjct: 493 GY-----ISSAFLFGATGK----YGNQVSEHTLGTVHTHSAHFKVDLDVAGLENWVWAED 543 Query: 578 PVVKPNT---AGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLS-NPNKENRMGNPVSY 633 V P + + +QV + + E+ AA T R L N N+ G+P Y Sbjct: 544 MVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAFLVGSATPRYLYLASNHSNKWGHPRGY 603 Query: 634 QIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTG 693 +I + P+ + + A S+ QL VT+ E + N++ Sbjct: 604 RIQMLSFAGEPLPQNSSMA------RGFSWERYQLAVTQRKEEEPSSSSVF-NQNDPWAP 656 Query: 694 LGQYSK--DNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTEWVHTLLKPWNFFDETPT 749 +S +NE++ D V W+T G H+ AE+ P + V L+P+NFFDE P+ Sbjct: 657 TVDFSDFINNETIAGKDLVAWVTAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDEDPS 716 Query: 750 L 750 Sbjct: 717 F 717 >1RKY-A nrPDB Length = 747 Score = 129 bits (323), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 136/518 (26%), Positives = 220/518 (42%), Gaps = 53/518 (10%) Query: 246 DAKKVITTPLTVGYFDGKDGLKQDARLLKVISYL------DVGDGNYWAHPIENLVAV-- 297 DA+ ++ T G+F D +D K++ Y+ + Y A ++ V + Sbjct: 200 DAENLVPT----GFFFKFDMTGRDVSQWKMLEYIYNNKVYTSAEELYEAMQKDDFVTLPK 255 Query: 298 VDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGD--MIHW 355 +D++ I+ PV R D DR +P +++EPEG+ + GD W Sbjct: 256 IDVDNLDWTVIQRNDSAPV----RHLD--DRKSP-----RLVEPEGRRWAYDGDEEYFSW 304 Query: 356 RNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSG 415 +W F+ S + G +T+ +++YE SL +I YG D Y D Sbjct: 305 MDWGFYTSWSRDTGISFYDITFK----GERIVYELSLQELIAEYGSDDPFNQHTFYSDIS 360 Query: 416 DYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQ 475 YG+G S + G D PS A +Y + VFE Sbjct: 361 -YGVGNRFS-LVPGYDCPSTAGYFTTDTFEYDEF-YNRTLSYCVFENQEDYSLLRHTGAS 417 Query: 476 PNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETA 535 + T+ L VR+IST+GNYDY F + F +GT+ + A G ++A + ET+ Sbjct: 418 YSAITQNPTLNVRFISTIGNYDYNFLYKFFLDGTLEVSVRAAGY-----IQAGYWNPETS 472 Query: 536 KDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENN---SLVAMDPVVKPNTAGGPRTST 592 YG I + G+ H H+ N+++DLDV G N V D V+ A G +T Sbjct: 473 ---APYGLKIHDVLSGSFHDHVLNYKVDLDVGGTKNRASQYVMKDVDVEYPWAPGTVYNT 529 Query: 593 MQVNQYNIGNEQDAAQKF--DPGTIRLLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQ 650 Q+ + NE + + I L+ + + N GNP +Y I+P GG H + K ++ Sbjct: 530 KQIAREVFENEDFNGINWPENGQGILLIESAEETNSFGNPRAYNIMPGGGGVHRIVKNSR 589 Query: 651 FAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLG-QYSKDNESLDNTDA 709 P+ + R L++T++ E + +D + D+ESLD D Sbjct: 590 SGPETQNWAR-----SNLFLTKHKDTELRSSTALNTNALYDPPVNFNAFLDDESLDGEDI 644 Query: 710 VVWMTTGTTHVARAEEWP--IMPTEWVHTLLKPWNFFD 745 V W+ G H+ + + P I T +L P+N+FD Sbjct: 645 VAWVNLGLHHLPNSNDLPNTIFSTAHASFMLTPFNYFD 682 >4XQ7-A nrPDB Length = 359 Score = 35.8 bits (81), Expect = 0.079, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 24/45 (53%) Query: 241 KRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGN 285 K + DA + + L +F GK GL QD R+LKV+ G+G Sbjct: 30 KEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGT 74 >1MVN-A nrPDB Length = 209 Score = 33.9 bits (76), Expect = 0.30, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 10/70 (14%) Query: 356 RNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSG 415 R WD+ + V P ++T+ +N+ T+R ++ LG ++P K L SG Sbjct: 127 RAWDYTKPL--FVAPAMNTLMWNNPFTERHLLSLDELGITLIPP--------IKKRLASG 176 Query: 416 DYGMGTLTSP 425 DYG G + P Sbjct: 177 DYGNGAMAEP 186 >5M1C-A nrPDB Length = 517 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 15/26 (57%), Gaps = 1/26 (3%) Query: 655 EWIYHRLSFMDKQLWVTRYHPGERFP 680 W+ HR +D Q W HPGERFP Sbjct: 212 RWLSHRGGALDYQEWCAA-HPGERFP 236 >4F10-A nrPDB Length = 353 Score = 30.8 bits (68), Expect = 2.0, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 473 MGQPNVSTERRELVVRWISTVGNYDYIF 500 M +PNV T +RE VV+W++ V + F Sbjct: 151 MAEPNVDTAQRERVVKWLNRVARHQTSF 178 >1S7D-A nrPDB Length = 216 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 32/101 (31%), Positives = 44/101 (43%), Gaps = 12/101 (11%) Query: 16 LAVALS-FAWQAPVFAHGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIK-DGAYVKVKP 73 LAVAL F AP F+HG +H P+ + ++ V D Q TL DG + V P Sbjct: 8 LAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGVFDDANVQNRTLSDWDGVWQSVYP 67 Query: 74 GAQTAIVNGQPLALQVPVVMKDNKAWVSDTF--INDVFQSG 112 Q+ ++ PV K A + TF I D + G Sbjct: 68 LLQSGKLD--------PVFQKKADADKTKTFAEIKDYYHKG 100 >3LFI-A nrPDB Length = 634 Score = 29.3 bits (64), Expect = 7.3, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 21/51 (41%) Query: 389 EGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLL 439 EG +G Y DP G + +L GD G T+ +A D N L Sbjct: 36 EGQIGDPCAHYTDPSTGLFHVGFLHDGDGIAGATTANLATYTDTSDNGSFL 86 >2YCH-A nrPDB Length = 377 Score = 29.3 bits (64), Expect = 7.5, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 22/43 (51%) Query: 177 DQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLL 219 D+P V+ L GK EA+ N LL+ + +K +GM L Sbjct: 211 DKPLAVRVLTLSGKDFTEAIARSFNLDLLAAEEVKRTYGMATL 253 >2OCZ-A nrPDB Length = 231 Score = 28.9 bits (63), Expect = 8.0, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 6/56 (10%) Query: 458 AVFERYAGPEYKH-----QEMGQPNVSTERRELVVRWISTVGNYDYI-FDWIFHEN 507 A+FE++AG E QE G +S++ +++ I+ + N DYI F++ H++ Sbjct: 50 AIFEKFAGKEIIFTLRTVQEGGNITLSSQEYVDIIKEINAIYNPDYIDFEYFTHKS 105 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1D6Z-A nrPDB 1055 0.0 1KSI-A nrPDB 704 0.0 3NBJ-A nrPDB 678 0.0 2CG0-A nrPDB 678 0.0 3LOY-A nrPDB 663 0.0 1RKY-A nrPDB 502 e-142 2PNC-A nrPDB 494 e-140 1US1-A nrPDB 483 e-136 3K5T-A nrPDB 460 e-129 3PGB-A nrPDB 456 e-128 Sequences not found previously or not previously below threshold: 1S7D-A nrPDB 39 0.009 3LL5-A nrPDB 34 0.30 5VKU-g nrPDB 33 0.45 1UYP-A nrPDB 31 1.4 3TXV-A nrPDB 31 1.5 2Y8V-A nrPDB 30 3.4 CONVERGED! >1D6Z-A nrPDB Length = 727 Score = 1055 bits (2728), Expect = 0.0, Method: Composition-based stats. Identities = 727/727 (100%), Positives = 727/727 (100%) Query: 31 HGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVP 90 HGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVP Sbjct: 1 HGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVP 60 Query: 91 VVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPN 150 VVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPN Sbjct: 61 VVMKDNKAWVSDTFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPN 120 Query: 151 TRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPI 210 TRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPI Sbjct: 121 TRFTEISLLPPDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPI 180 Query: 211 KDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDA 270 KDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDA Sbjct: 181 KDAHGMVLLDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDA 240 Query: 271 RLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVA 330 RLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVA Sbjct: 241 RLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVA 300 Query: 331 PAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEG 390 PAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEG Sbjct: 301 PAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEG 360 Query: 391 SLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP 450 SLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP Sbjct: 361 SLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP 420 Query: 451 MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTI 510 MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTI Sbjct: 421 MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTI 480 Query: 511 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN 570 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN Sbjct: 481 GIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGEN 540 Query: 571 NSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNP 630 NSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNP Sbjct: 541 NSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKENRMGNP 600 Query: 631 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH 690 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH Sbjct: 601 VSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTH 660 Query: 691 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 750 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL Sbjct: 661 DTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 720 Query: 751 GALKKDK 757 GALKKDK Sbjct: 721 GALKKDK 727 >1KSI-A nrPDB Length = 642 Score = 704 bits (1817), Expect = 0.0, Method: Composition-based stats. Identities = 193/645 (29%), Positives = 304/645 (47%), Gaps = 30/645 (4%) Query: 124 HPLNALTADEIKQAVEIVKASADFKPN-TRFTEISLLPPDKEAVWAFALENKPVDQPRKA 182 HPL+ LT +E IV+ N F I L P+K+ V + V PRK Sbjct: 3 HPLDPLTKEEFLAVQTIVQNKYPISNNRLAFHYIGLDDPEKDHVLRYETHPTLVSIPRKI 62 Query: 183 DVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLL--DDFASVQNIINNSEEFAAAVK 240 V+ + E +++L+ ++S I + +G +L D+ + + F +VK Sbjct: 63 FVVAIINSQTHEILINLRIRSIVS-DNIHNGYGFPILSVDEQSLAIKLPLKYPPFIDSVK 121 Query: 241 KRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDL 300 KRG+ + +++ + T+G+F G +++ R +++ ++ N + PI + V DL Sbjct: 122 KRGL-NLSEIVCSSFTMGWF----GEEKNVRTVRLDCFMKESTVNIYVRPITGITIVADL 176 Query: 301 EQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQII----EPEGKNYTITGDMIHWR 356 + KIV+ + + VP + +P P Q +P+G + I G + W Sbjct: 177 DLMKIVEYHDRDIEAVPTAENTEYQVSKQSPPFGPKQHSLTSHQPQGPGFQINGHSVSWA 236 Query: 357 NWDFHLSMNSRVGPMISTVTYND--NGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDS 414 NW FH+ + R G +IS + D R+V+Y+G + + VPY DP +YFK + DS Sbjct: 237 NWKFHIGFDVRAGIVISLASIYDLEKHKSRRVLYKGYISELFVPYQDPTEEFYFKTFFDS 296 Query: 415 GDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMG 474 G++G G T + +D P +A ++ + G P+ + AI VFE+Y ++H E G Sbjct: 297 GEFGFGLSTVSLIPNRDCPPHAQFIDTYVHSANGTPILLKNAICVFEQYGNIMWRHTENG 356 Query: 475 QPNVSTERRE----LVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTM 530 PN S E L+VR I TVGNYD + DW F +G+I +GI +KG K Sbjct: 357 IPNESIEESRTEVNLIVRTIVTVGNYDNVIDWEFKASGSIKPSIALSGILEIKGTNIK-- 414 Query: 531 HDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMD-PVVKPNTAGGPR 589 H + K+D +G L+ N +G H H Y + LD D+DG +NS V+ R Sbjct: 415 HKDEIKEDL-HGKLVSANSIGIYHDHFYIYYLDFDIDGTHNSFEKTSLKTVRIKDGSSKR 473 Query: 590 TSTMQVNQYNIGNEQDAAQKFDPGTIRLLS-NPNKENRMGNPVSYQIIPYAGGTHPVAKG 648 S E DA L+ NPN + +GN V Y++IP A HP+ Sbjct: 474 KSYWTTETQTAKTESDAKITIGLAPAELVVVNPNIKTAVGNEVGYRLIP-AIPAHPL--- 529 Query: 649 AQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTD 708 D++ R +F + +WVT Y+ E++ G Y + S D L ++K N + N D Sbjct: 530 --LTEDDYPQIRGAFTNYNVWVTAYNRTEKWAGGLYVDHSRGDDTLAVWTKQNREIVNKD 587 Query: 709 AVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTLGAL 753 V+W G HV E++PIMP L+P NFF+ P L L Sbjct: 588 IVMWHVVGIHHVPAQEDFPIMPLLSTSFELRPTNFFERNPVLKTL 632 >3NBJ-A nrPDB Length = 692 Score = 678 bits (1750), Expect = 0.0, Method: Composition-based stats. Identities = 176/658 (26%), Positives = 308/658 (46%), Gaps = 56/658 (8%) Query: 124 HPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKAD 183 HPL+ L+ EIK A VK+ K F ++L P ++A + + P+ PR A Sbjct: 23 HPLDPLSTAEIKAATNTVKSYFAGK-KISFNTVTLREPARKAYIQWKEQGGPLP-PRLAY 80 Query: 184 VIMLDGKHI--IEAVVDLQNNKLLSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAAVKK 241 ++L+ E +VDL + ++ + ++ ++ ++D S + +I N Sbjct: 81 YVILEAGKPGVKEGLVDLASLSVIETRALETVQPILTVEDLCSTEEVIRNDPAVIEQCVL 140 Query: 242 RGIT--DAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDG-NYWAHPIENLVAVV 298 GI + KV P T+GY D + G + RL + + Y + + ++HP++ +V Sbjct: 141 SGIPANEMHKVYCDPWTIGY-DERWGTGK--RLQQALVYYRSDEDDSQYSHPLD-FCPIV 196 Query: 299 DLEQKKIVKIEEGPVVPVPMTARPFDGRDR--------------VAPAVKPMQIIEPEGK 344 D E+KK++ I+ +P R + P P+ + +PEG Sbjct: 197 DTEEKKVIFID------IPNRRRKVSKHKHANFYPKHMIEKVGAMRPEAPPINVTQPEGV 250 Query: 345 NYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDI 404 ++ +TG+++ W N+ FH+ N R G ++S V+YND+G R + + SL MIVP+G P+ Sbjct: 251 SFKMTGNVMEWSNFKFHIGFNYREGIVLSDVSYNDHGNVRPIFHRISLSEMIVPFGSPEF 310 Query: 405 GWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYA 464 K LD G+YG G +T+P++ G D L+ +D G P+ + A+ + E Sbjct: 311 PHQRKHALDIGEYGAGYMTNPLSLGCDCKGVIHYLDAHFSDRAGDPITVKNAVCIHEEDD 370 Query: 465 GPEYKHQEMGQ---PNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEA 521 G +KH + ++ T +LVV I T N +Y W+F ++G I +D TGI Sbjct: 371 GLLFKHSDFRDNFATSLVTRATKLVVSQIFTAANXEYCLYWVFMQDGAIRLDIRLTGI-- 428 Query: 522 VKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVK 581 + + D+ ++ +GT + N+ HQH+++ R+D +DG+ NS A D Sbjct: 429 ---LNTYILGDD--EEAGPWGTRVYPNVNAHNHQHLFSLRIDPRIDGDGNSAAACDAKSS 483 Query: 582 PNTAGGPRT---STMQVNQYNIGNEQDAAQKFDPGTIRL--LSNPNKENRM-GNPVSYQI 635 P G P + + +D+ ++ T R + NPNK N G P SY++ Sbjct: 484 PYPLGSPENMYGNAFYSEKTTFKTVKDSLTNYESATGRSWDIFNPNKVNPYSGKPPSYKL 543 Query: 636 IPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHD--TG 693 + +G+ A R + + V Y +P G + + + D G Sbjct: 544 VSTQCPPLLAKEGSLVA------KRAPWASHSVNVVPYKDNRLYPSGDHVPQWSGDGVRG 597 Query: 694 LGQYSKD-NESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTL 750 + ++ D +E++DNTD + + T G TH E++P+ P E + +L+P +FF E P L Sbjct: 598 MREWIGDGSENIDNTDILFFHTFGITHFPAPEDFPLXPAEPITLMLRPRHFFTENPGL 655 >2CG0-A nrPDB Length = 646 Score = 678 bits (1749), Expect = 0.0, Method: Composition-based stats. Identities = 183/639 (28%), Positives = 306/639 (47%), Gaps = 35/639 (5%) Query: 125 PLNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKADV 184 P +A EI + I++ + P R + +L P + A ++ D+ + + Sbjct: 9 PFRLASAGEISEVQGILRTAGLLGPEKRIAYLGVLDPARGA------GSEAEDRRFRVFI 62 Query: 185 IMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVL---LDDFASVQNIINNSEEFAAAVKK 241 + G E V + N ++S + A L ++F V+ ++ E + A+ Sbjct: 63 HDVSGARPQEVTVSVTNGTVISAVELDTAATGELPVLEEEFEVVEQLLATDERWLKALAA 122 Query: 242 RGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYL-DVGDGNYWAHPIENLVAVVDL 300 R + D KV PL+ G F+ + ++ R+L+ ++++ D + + WAHP++ LVA VD+ Sbjct: 123 RNL-DVSKVRVAPLSAGVFEYAE--ERGRRILRGLAFVQDFPEDSAWAHPVDGLVAYVDV 179 Query: 301 EQKKIVKIEEGPVVPVPMTARPFDGRDRVAP---AVKPMQIIEPEGKNYTITG-DMIHWR 356 K++ ++ + V PVP + + P KP+ I +PEG ++T+TG + I W Sbjct: 180 VSKEVTRVIDTGVFPVPAEHGNYTDPELTGPLRTTQKPISITQPEGPSFTVTGGNHIEWE 239 Query: 357 NWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGD 416 W + + R G ++ + + D R ++ S+ M+VPYGDP ++ Y D+G+ Sbjct: 240 KWSLDVGFDVREGVVLHNIAFRDGDRLRPIINRASIAEMVVPYGDPSPIRSWQNYFDTGE 299 Query: 417 YGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEM-GQ 475 Y +G + + G D + L+ I+D G P EI I + E G KH ++ Sbjct: 300 YLVGQYANSLELGCDCLGDITYLSPVISDAFGNPREIRNGICMHEEDWGILAKHSDLWSG 359 Query: 476 PNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETA 535 N + R +V+ + +T+GNYDY F W + +GTI +A ATG V + E Sbjct: 360 INYTRRNRRMVISFFTTIGNYDYGFYWYLYLDGTIEFEAKATG------VVFTSAFPEGG 413 Query: 536 KDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKPNTAGGPRTSTMQV 595 D+ + + + HQHI++ RLD+ +DG N + D V + G R + Sbjct: 414 SDNI---SQLAPGLGAPFHQHIFSARLDMAIDGFTNRVEEEDVVRQTMGPGNERGNAFSR 470 Query: 596 NQYNIGNEQDAAQKFDPGTIR--LLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAP 653 + + E +A ++ D T R ++SNP +NR+ PV Y++ + T G+ A Sbjct: 471 KRTVLTRESEAVREADARTGRTWIISNPESKNRLNEPVGYKLHAHNQPTLLADPGSSIA- 529 Query: 654 DEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDNESLDNTDAVVWM 713 R +F K LWVTRY ER+P G + N+ + GL Y + +D D VVW Sbjct: 530 -----RRAAFATKDLWVTRYADDERYPTGDFVNQHSGGAGLPSYIAQDRDIDGQDIVVWH 584 Query: 714 TTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTLGA 752 T G TH R E+WPIMP + V L+P FFD +P L Sbjct: 585 TFGLTHFPRVEDWPIMPVDTVGFKLRPEGFFDRSPVLDV 623 >3LOY-A nrPDB Length = 633 Score = 663 bits (1709), Expect = 0.0, Method: Composition-based stats. Identities = 174/661 (26%), Positives = 295/661 (44%), Gaps = 65/661 (9%) Query: 124 HPLNALTADEIKQAVEIVKASADFKPNTRFTEIS-LLPPDKEAVWAFALEN--KPVDQ-P 179 HP + ++ E++ +++K + F +I L PP K+ + E KP+ Sbjct: 2 HPYDPISDAELQLTSQLIKDATKGPERPHFIQIDRLDPPKKDMIRYLEAERTGKPLPHIS 61 Query: 180 RKADVIMLDGKHIIEAVVDLQNNKLLSWQPI-KDAHGMVLLDDFASVQNIINNSEEFAAA 238 R V G +A+V++ +++ Q K G ++ +D ++ + A Sbjct: 62 RMTYVYYYIGLDFYKALVNVSYGHIITNQKQPKGVIGPLIAEDIQEIEELATTHPIVKAE 121 Query: 239 VKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDV---GDGNYWAHPIENLV 295 ++K + +V+ P + +G D K+D L++ YL + N+++ P++ Sbjct: 122 IEKLKLPPHVRVVCDP----WMNGTDS-KEDRMLIQCYMYLASAAHPESNHYSLPLK-FS 175 Query: 296 AVVDLEQKKIVKIEEGPVVP------------VPMTARPFDGRDRVAPAVKPMQIIEPEG 343 V + KK V+++ P P D +KP+ + +PEG Sbjct: 176 PVFECLTKKFVRMDYLPGGADETVTETQAWDEFPFVEYHPDLNGETIVPLKPLIVQQPEG 235 Query: 344 KNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPD 403 ++ + G I W+ W+F + R G I + + R V+Y SL M VPYGDP Sbjct: 236 PSFNVDGHKISWQGWEFFVIPTVREGFAIYDIHFK----GRSVVYRLSLSEMTVPYGDPR 291 Query: 404 IGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERY 463 ++ K D GD G G + +A G D ++ + G + IP + + E+ Sbjct: 292 APFHRKQAFDLGDCGFGATGNSLALGCDCLGVIKYMDCRRVNTNGDSVLIPNTVCLHEQD 351 Query: 464 AGPEYKHQEMGQPNVST--ERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEA 521 G YKH + NV RRE VV+ I+TV NY+Y+ + IF + G I I ATGI + Sbjct: 352 GGLLYKHTNY-RTNVPVIARRREFVVQTIATVANYEYMLNIIFDQAGEIRIHVRATGILS 410 Query: 522 VKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVK 581 + +GT + ++ HQH+ +FR+D VDG N++V D + Sbjct: 411 TMPLDKDV--------TVPWGTNVGPRVMAAYHQHMLSFRIDPAVDGYENTVVFDDVIR- 461 Query: 582 PNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRL---------LSNPNKENRMGN-PV 631 ++N YN+G + PG + + N NK N + PV Sbjct: 462 -------MEKNTKLNPYNVGFVTERTVVEKPGYVEQSPFTNRSYKIINENKINPISKKPV 514 Query: 632 SYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHD 691 +Y+I+ P + D + R F +Q+WVT+Y E + G++ N+S D Sbjct: 515 AYKIM------MPARQMLLADEDSYNNKRAQFATQQVWVTKYRDNELYAAGEFTNQSQTD 568 Query: 692 TGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKPWNFFDETPTLG 751 TGLG +++ +E++ N + VVW T G TH+ R E++P+MP E L P+ FFD+ P L Sbjct: 569 TGLGVWARRDENVRNDNPVVWATLGFTHIPRVEDFPVMPVEAHEIALVPFGFFDKNPALS 628 Query: 752 A 752 Sbjct: 629 V 629 >1RKY-A nrPDB Length = 747 Score = 502 bits (1292), Expect = e-142, Method: Composition-based stats. Identities = 139/600 (23%), Positives = 235/600 (39%), Gaps = 58/600 (9%) Query: 179 PRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLLDDFASVQNIINNSEEFAAA 238 P + + + ++ N + ++ G+ D + A Sbjct: 128 PFEVGHLDRIKSAAKSSFLNKNLNTTIMRDVLEGLIGVPYEDMGCHSAAPQLHDPATGAT 187 Query: 239 -----VKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISY------LDVGDGNYW 287 DA+ ++ T G+F D +D K++ Y + Y Sbjct: 188 VDYGTCNINTENDAENLVPT----GFFFKFDMTGRDVSQWKMLEYIYNNKVYTSAEELYE 243 Query: 288 AHPIENLVAV--VDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKN 345 A ++ V + +D++ I+ PV R D DR +P +++EPEG+ Sbjct: 244 AMQKDDFVTLPKIDVDNLDWTVIQRNDSAPV----RHLD--DRKSP-----RLVEPEGRR 292 Query: 346 YTITGD--MIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPD 403 + GD W +W F+ S + G +T+ +++YE SL +I YG D Sbjct: 293 WAYDGDEEYFSWMDWGFYTSWSRDTGISFYDITFKGE----RIVYELSLQELIAEYGSDD 348 Query: 404 IGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERY 463 Y D YG+G + G D PS A +Y + VFE Sbjct: 349 PFNQHTFYSDIS-YGVGNRF-SLVPGYDCPSTAGYFTTDTFEYDEF-YNRTLSYCVFENQ 405 Query: 464 AGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVK 523 + T+ L VR+IST+GNYDY F + F +GT+ + A G Sbjct: 406 EDYSLLRHTGASYSAITQNPTLNVRFISTIGNYDYNFLYKFFLDGTLEVSVRAAGY---- 461 Query: 524 GVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENN---SLVAMDPVV 580 ++A + ET+ YG I + G+ H H+ N+++DLDV G N V D V Sbjct: 462 -IQAGYWNPETSA---PYGLKIHDVLSGSFHDHVLNYKVDLDVGGTKNRASQYVMKDVDV 517 Query: 581 KPNTAGGPRTSTMQVNQYNIGNEQDAAQKF--DPGTIRLLSNPNKENRMGNPVSYQIIPY 638 + A G +T Q+ + NE + + I L+ + + N GNP +Y I+P Sbjct: 518 EYPWAPGTVYNTKQIAREVFENEDFNGINWPENGQGILLIESAEETNSFGNPRAYNIMPG 577 Query: 639 AGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLG-QY 697 GG H + K ++ P+ + L++T++ E + +D + Sbjct: 578 GGGVHRIVKNSRSGPETQN-----WARSNLFLTKHKDTELRSSTALNTNALYDPPVNFNA 632 Query: 698 SKDNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTEWVHTLLKPWNFFDETPTLGALKK 755 D+ESLD D V W+ G H+ + + P I T +L P+N+FD + ++ Sbjct: 633 FLDDESLDGEDIVAWVNLGLHHLPNSNDLPNTIFSTAHASFMLTPFNYFDSENSRDTTQQ 692 >2PNC-A nrPDB Length = 746 Score = 494 bits (1272), Expect = e-140, Method: Composition-based stats. Identities = 158/701 (22%), Positives = 268/701 (38%), Gaps = 83/701 (11%) Query: 110 QSGLDQTFQVEKRPHPLNALTADEIKQAVE---------IVKASADFKPNTRFTEISLLP 160 +S DQ + + L+ +E+ + +V A+ + + L Sbjct: 27 RSPSDQPWTHPDQSQLFADLSREELTTVMSFLTQQLGPDLVDAAQARPSDNCVFSVELQL 86 Query: 161 PDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDA----HGM 216 P K A A P R+A I+ G V +L L ++D HG Sbjct: 87 PPKAAALAHLDRGSP-PPAREALAIVFFGGQPQPNVTELVVGPLPQPSYMRDVTVERHGG 145 Query: 217 VL--------LDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQ 268 L L ++ + +I N E AA K+ LT+ Sbjct: 146 PLPYYRRPVLLREYLDIDQMIFNRELPQAAGVLHHCCSYKQGGQKLLTMNSAPRGVQSG- 204 Query: 269 DARLLKVISYLDVGDGNYWAHPIENLVAVVD---LEQKKIV--------KIEEG------ 311 D I Y ++ G + HP+ L +VD L+ + E Sbjct: 205 DRSTWFGI-YYNITKGGPYLHPV-GLELLVDHKALDPADWTVQKVFFQGRYYENLAQLEE 262 Query: 312 ---------PVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDFHL 362 V+P T + + +V P P P+G +++ G+ + W F Sbjct: 263 QFEAGQVNVVVIPDDGTGGFWSLKSQVPPGPTPPLQFHPQGPRFSVQGNRVASSLWTFSF 322 Query: 363 SMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTL 422 + + GP + V + ++ YE SL YG Y+DSG +GMG Sbjct: 323 GLGAFSGPRVFDVRFQGE----RLAYEISLQEAGAVYGGNTPAAMLTRYMDSG-FGMGYF 377 Query: 423 TSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAG-PEYKHQE--MGQPNVS 479 +P+ RG D P A ++ + P + A VFE+ G P +H + Sbjct: 378 ATPLIRGVDCPYLATYMDWHFVVESQTPKTLHDAFCVFEQNKGLPLRRHHSDFLSHYFGG 437 Query: 480 TERRELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDT 539 + LV R +ST+ NYDY++D +F+ NG I + ATG + + Sbjct: 438 VAQTVLVFRSVSTMLNYDYVWDMVFYPNGAIEVKLHATGYISSAFLFGA---------AR 488 Query: 540 RYGTLIDHNIVGTTHQHIYNFRLDLDVDGENNSLVAMDPVVKP---NTAGGPRTSTMQVN 596 RYG + + +G H H ++++DLDV G N + A D P + + +QV Sbjct: 489 RYGNQVGEHTLGPVHTHSAHYKVDLDVGGLENWVWAEDMAFVPTAIPWSPEHQIQRLQVT 548 Query: 597 QYNIGNEQDAAQKFDPGTIRLLSNPNKE-NRMGNPVSYQIIPYAGGTHPVAKGAQFAPDE 655 + + E+ AA + R L +K+ N+ G+P Y+I + P+ + + Sbjct: 549 RKQLETEEQAAFPLGGASPRYLYLASKQSNKWGHPRGYRIQTVSFAGGPMPQNSPM---- 604 Query: 656 WIYHRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSK--DNESLDNTDAVVWM 713 S+ QL +T+ E + N++ T +S +NE++ D V W+ Sbjct: 605 --ERAFSWGRYQLAITQRKETEPSSSSVF-NQNDPWTPTVDFSDFINNETIAGKDLVAWV 661 Query: 714 TTGTTHVARAEEWP--IMPTEWVHTLLKPWNFFDETPTLGA 752 T G H+ AE+ P + V L+P+NFFD+ P++ + Sbjct: 662 TAGFLHIPHAEDIPNTVTVGNGVGFFLRPYNFFDQEPSMDS 702 >1US1-A nrPDB Length = 763 Score = 483 bits (1243), Expect = e-136, Method: Composition-based stats. Identities = 123/447 (27%), Positives = 191/447 (42%), Gaps = 32/447 (7%) Query: 315 PVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMIST 374 P T + + V P P P+G +++ G + W F + + GP I Sbjct: 292 PDNGTGGSWSLKSPVPPGPAPPLQFYPQGPRFSVQGSRVASSLWTFSFGLGAFSGPRIFD 351 Query: 375 VTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPS 434 V + +++YE SL + YG Y+D G +GMG T+P+ RG D P Sbjct: 352 VRFQGE----RLVYEISLQEALAIYGGNSPAAMTTRYVDGG-FGMGKYTTPLTRGVDCPY 406 Query: 435 NAVLLNETIADYTGVPMEIPRAIAVFERYAG-PEYKHQE--MGQPNVSTERRELVVRWIS 491 A ++ + P I A VFE+ G P +H LVVR +S Sbjct: 407 LATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSHYFGGLAETVLVVRSMS 466 Query: 492 TVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVG 551 T+ NYDY++D +FH +G I I ATG + + T +YG + + +G Sbjct: 467 TLLNYDYVWDTVFHPSGAIEIRFYATGYISSAFLFGAT---------GKYGNQVSEHTLG 517 Query: 552 TTHQHIYNFRLDLDVDGENNSLVAMDPVVKPN---TAGGPRTSTMQVNQYNIGNEQDAAQ 608 T H H +F++DLDV G N + A D V P + + +QV + + E+ AA Sbjct: 518 TVHTHSAHFKVDLDVAGLENWVWAEDMVFVPMAVPWSPEHQLQRLQVTRKLLEMEEQAAF 577 Query: 609 KFDPGTIRLLS-NPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQ 667 T R L N N+ G+P Y+I + P+ + + A S+ Q Sbjct: 578 LVGSATPRYLYLASNHSNKWGHPRGYRIQMLSFAGEPLPQNSSMA------RGFSWERYQ 631 Query: 668 LWVTRYHPGERFPEGKYPNRSTHDTGLGQYSK--DNESLDNTDAVVWMTTGTTHVARAEE 725 L VT+ E + N++ +S +NE++ D V W+T G H+ AE+ Sbjct: 632 LAVTQRKEEEPSSSSVF-NQNDPWAPTVDFSDFINNETIAGKDLVAWVTAGFLHIPHAED 690 Query: 726 WP--IMPTEWVHTLLKPWNFFDETPTL 750 P + V L+P+NFFDE P+ Sbjct: 691 IPNTVTVGNGVGFFLRPYNFFDEDPSF 717 >3K5T-A nrPDB Length = 731 Score = 460 bits (1182), Expect = e-129, Method: Composition-based stats. Identities = 125/490 (25%), Positives = 206/490 (42%), Gaps = 36/490 (7%) Query: 278 YLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQ 337 + + + + VV + K + P ++ G V + Sbjct: 222 FYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPR 281 Query: 338 IIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIV 397 +++P G + + G+ + + W F + S G + V + ++ YE S+ + Sbjct: 282 LVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGE----RIAYEVSVQEAVA 337 Query: 398 PYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVPMEIPRAI 457 YG YLD G +G+G++T +A G D P A L+ P+ PRA+ Sbjct: 338 LYGGHTPAGMQTKYLDVG-WGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRAL 396 Query: 458 AVFERYAGPEYKHQEMGQPN------VSTERRELVVRWISTVGNYDYIFDWIFHENGTIG 511 +FE G + + + LV+R STV NYDYI+D+IF+ NG + Sbjct: 397 CLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVME 456 Query: 512 IDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDVDGENN 571 ATG V A E R+GT + +++G H H+ ++R+DLDV G N Sbjct: 457 AKMHATGY-----VHATFYTPE----GLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKN 507 Query: 572 SLVAMDPVVKPNT-AGGPRTSTMQ--VNQYNIGNEQDAAQKFDPGTIRL-LSNPNKENRM 627 S + ++ T PR +Q + Q E+ AA +F + L +EN Sbjct: 508 SFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPW 567 Query: 628 GNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRL-SFMDKQLWVTRYHPGERFPEGKYPN 686 G+ SY++ H +A Q P W + ++ L VT+Y E Y Sbjct: 568 GHKRSYRL-----QIHSMAD--QVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQ 620 Query: 687 RSTHDTGL--GQYSKDNESLDNTDAVVWMTTGTTHVARAEEWP--IMPTEWVHTLLKPWN 742 D + Q+ +NE+++N D V W+T G H+ +E+ P P V LL+P+N Sbjct: 621 NDPWDPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFN 680 Query: 743 FFDETPTLGA 752 FF E P+L + Sbjct: 681 FFPEDPSLAS 690 >3PGB-A nrPDB Length = 797 Score = 456 bits (1174), Expect = e-128, Method: Composition-based stats. Identities = 129/518 (24%), Positives = 220/518 (42%), Gaps = 52/518 (10%) Query: 253 TPLTVGYFDGKDGLKQDARLLKVI------SYLDVGDGNYWAHPIENLVAVVDLEQKKIV 306 T L +G + D +D K++ + + + A+ V + Sbjct: 252 TLLPLGLYLKSDVTGRDPSQWKLLGWMYNDIFYETTEEFRKAYWSPGFVKLKPNVDGAWA 311 Query: 307 KI-EEGPVVPVPMTARPFDGRDRVAPAVKPMQIIEPEGKNYTITGD--MIHWRNWDFHLS 363 + GPV P +DR P V +I P+G Y++ + + W ++ F+++ Sbjct: 312 HTEQRGPVPP----------QDRKQPPV----MIAPDGARYSVDAERKYVTWMDFSFYIA 357 Query: 364 MNSRVGPMISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLT 423 N G + + Y ++V+YE L + Y D AYLDS YG G Sbjct: 358 FNRDTGLSLFDIKYK----GQRVLYELGLQEALAHYAANDPVQSSVAYLDSY-YGFGPYA 412 Query: 424 SPIARGKDAPSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQPNVSTERR 483 + +G D PS A LN + + ++ +FE A + T+ Sbjct: 413 FELLKGYDCPSYASYLNTSFYKDEETHTHV-DSLCLFEFDADYPMARHSTSEFVSVTKNV 471 Query: 484 ELVVRWISTVGNYDYIFDWIFHENGTIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGT 543 +R +ST+GNYDY+F + FH +GTIG++ A+G + ++ +G Sbjct: 472 YFTLRSVSTIGNYDYMFSYNFHMDGTIGVEVRASGY----------IQSAYYANNQDFGY 521 Query: 544 LIDHNIVGTTHQHIYNFRLDLDVDGENNS--LVAMDPVVKPNTAGGPRT-STMQVNQYNI 600 I ++ G+ H H+ NF+ D D+ G NN+ LV++ PV K + G +T +TMQ+ + I Sbjct: 522 QIHDSLSGSMHDHVLNFKADFDILGPNNTIELVSVVPVTKQFSWSGNKTRNTMQLGRSFI 581 Query: 601 GNEQDAAQKF--DPGTIRLLSNPNKENRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIY 658 +E +A + + T + N +K N+ G P Y+I+P AG H + + Sbjct: 582 HSEDEARLNWGFNGQTQLHVVNQDKPNKFGEPRGYRILPSAGTAHLTVLNSSN-----LV 636 Query: 659 HRLSFMDKQLWVTRYHPGERFPEGKYPNRSTHDTGLGQYSKDN-ESLDNTDAVVWMTTGT 717 H + + + VTR H E Y ++ H+ + + N ESL+ TD VVW+ G Sbjct: 637 HAAHWAEYDVQVTRQHDFEPTSAHPYNSQDIHNPPVDFSTFFNGESLNQTDLVVWLNLGM 696 Query: 718 THVARAEEWP--IMPTEWVHTLLKPWNFFDETPTLGAL 753 HV + P + T P N+ P+ + Sbjct: 697 HHVPHTGDLPNTVFTTAHSGVAFTPLNYLPGDPSRETV 734 >1S7D-A nrPDB Length = 216 Score = 38.6 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 41/193 (21%), Positives = 71/193 (36%), Gaps = 19/193 (9%) Query: 16 LAVALS-FAWQAPVFAHGGEAHMVPMDKTLKEFGADVQWDDYAQLFTLIK-DGAYVKVKP 73 LAVAL F AP F+HG +H P+ + ++ V D Q TL DG + V P Sbjct: 8 LAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGVFDDANVQNRTLSDWDGVWQSVYP 67 Query: 74 GAQTAIVNGQPLALQVPVVMKDNKAWVSDTF--INDVFQSGLDQTFQ---VEK---RPHP 125 Q+ ++ PV K A + TF I D + G + +E H Sbjct: 68 LLQSGKLD--------PVFQKKADADKTKTFAEIKDYYHKGYATDIEMIGIEDGIVEFHR 119 Query: 126 LNALTADEIKQAVEIVKASADFKPNTRFTEISLLPPDKEAVWAFALENKPVDQPRKADVI 185 N T+ + + K R+ P+ +A + + + + Sbjct: 120 NNETTSCKYDYDGYKILTYKSGKKGVRYLF-ECKDPESKAPKYIQFSDHIIAPRKSSHFH 178 Query: 186 MLDGKHIIEAVVD 198 + G +++++ Sbjct: 179 IFMGNDSQQSLLN 191 >3LL5-A nrPDB Length = 249 Score = 33.6 bits (75), Expect = 0.30, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%) Query: 372 ISTVTYNDNGTKRKVMYEGSLGGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKD 431 IS + Y+ ++ G + V YGD I + SGD M + + Sbjct: 104 ISALRYDGRFDYTPLIRYIDAGFVPVSYGDVYIKDEHSYGIYSGDDIMADMAELLK---- 159 Query: 432 APSNAVLLNETIADYTGVPMEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWIS 491 P AV L + Y+ P P A+ + + + + ++ E +V+ S Sbjct: 160 -PDVAVFLTDVDGIYSKDPKRNPDAVLLRDIDTNITFDRVQNDVTGGIGKKFESMVKMKS 218 Query: 492 TVGNYDYIFD 501 +V N Y+ + Sbjct: 219 SVKNGVYLIN 228 >5VKU-g nrPDB Length = 290 Score = 33.2 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 10/77 (12%), Positives = 18/77 (23%), Gaps = 1/77 (1%) Query: 163 KEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVLLDDF 222 K+ + + V DG + L + + WQ + D + Sbjct: 169 KDMYLTWEETRGRLQYVYLIIVYDYDGPETRPGIYVLTS-SIAHWQTLVDVARGKFARER 227 Query: 223 ASVQNIINNSEEFAAAV 239 S N Sbjct: 228 CSFVNRRITRPRQIPLC 244 >1UYP-A nrPDB Length = 432 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 3/80 (3%) Query: 250 VITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIE 309 + T G F G +++D ++ V +Y N E V+ VK + Sbjct: 64 LYPDDETHGVFSGS-AVEKDGKMFLVYTYYRDPTHN--KGEKETQCVVMSENGLDFVKYD 120 Query: 310 EGPVVPVPMTARPFDGRDRV 329 PV+ P RD Sbjct: 121 GNPVISKPPEEGTHAFRDPK 140 >3TXV-A nrPDB Length = 450 Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 35/101 (34%), Gaps = 1/101 (0%) Query: 238 AVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVISYLDVGDGNYWAHPIENLVAV 297 A ++R + + + + + G ++ RL + SY D YW HP Sbjct: 313 AARERTLAEVTEAVMREEPANWAKYYHGSAEEQRLQRHFSYSDRIR-YYWPHPKAAAAVD 371 Query: 298 VDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVKPMQI 338 + V I E + + VAP KP+ + Sbjct: 372 ELMSLLDGVAIPETLISQFLAGSYARVRNGEVAPQAKPLAL 412 >2Y8V-A nrPDB Length = 290 Score = 30.2 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 14/39 (35%) Query: 350 GDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMY 388 G I W N F+ P + + ++V+Y Sbjct: 187 GSKISWYNAQFYNGWGLAEDPRMYAAIVAQGWSPQRVVY 225 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.123 0.320 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,599,553 Number of Sequences: 36641 Number of extensions: 1181797 Number of successful extensions: 2993 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 29 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 2815 Number of HSP's gapped (non-prelim): 50 length of query: 757 length of database: 10,336,785 effective HSP length: 105 effective length of query: 652 effective length of database: 6,489,480 effective search space: 4231140960 effective search space used: 4231140960 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)