BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46683 (200 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4BSZ-B nrPDB 407 e-114 5ET1-A nrPDB 48 3e-06 3EHQ-A nrPDB 46 1e-05 5CBO-A nrPDB 44 5e-05 3EU9-A nrPDB 43 8e-05 5AQ7-A nrPDB 43 1e-04 5U0K-A nrPDB 42 1e-04 5MIO-C nrPDB 42 2e-04 6BY9-A nrPDB 41 3e-04 2DWZ-A nrPDB 41 3e-04 5GP7-A nrPDB 41 3e-04 6MWQ-A nrPDB 41 4e-04 3B7B-A nrPDB 40 5e-04 5AQB-A nrPDB 40 6e-04 5AQ9-A nrPDB 40 0.001 4NIK-A nrPDB 39 0.002 6FES-A nrPDB 39 0.002 5UQE-A nrPDB 38 0.003 3LJN-A nrPDB 38 0.004 5D68-A nrPDB 38 0.004 5JHQ-A nrPDB 37 0.004 5U0J-A nrPDB 37 0.005 1WG0-A nrPDB 37 0.005 5HKP-A nrPDB 37 0.005 4Z68-A nrPDB 37 0.006 4OAU-C nrPDB 36 0.009 5H76-A nrPDB 36 0.010 5AQA-A nrPDB 36 0.013 1G3N-B nrPDB 33 0.088 6EMK-G nrPDB 32 0.21 3ZKJ-A nrPDB 32 0.22 4O1O-A nrPDB 31 0.29 3FY4-A nrPDB 31 0.32 4OT9-A nrPDB 31 0.35 6DMR-A nrPDB 30 0.68 6AUN-A nrPDB 29 1.3 2B0O-E nrPDB 28 2.4 3LVQ-E nrPDB 28 2.6 6BOA-A nrPDB 28 2.8 6E2G-A nrPDB 28 3.4 1YCD-A nrPDB 27 3.9 1D9S-A nrPDB 27 4.9 3G2U-A nrPDB 27 5.4 5EJK-A nrPDB 27 6.1 4UDE-A nrPDB 27 7.6 2RFA-A nrPDB 26 9.7 >4BSZ-B nrPDB Length = 202 Score = 407 bits (1045), Expect = e-114, Method: Compositional matrix adjust. Identities = 200/200 (100%), Positives = 200/200 (100%) Query: 1 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN 60 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN Sbjct: 3 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN 62 Query: 61 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP 120 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP Sbjct: 63 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP 122 Query: 121 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQV 180 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQV Sbjct: 123 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQV 182 Query: 181 TKEATEALREETEKLNINKD 200 TKEATEALREETEKLNINKD Sbjct: 183 TKEATEALREETEKLNINKD 202 >5ET1-A nrPDB Length = 353 Score = 48.1 bits (113), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 19/155 (12%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESESD---STALHMAAANGHIETVRYILETVSRA 76 A G L L+ + T C+ E D +T LH+AA GH + V+++L A Sbjct: 79 AATGYLSCLQWLLTQ-------GGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQ-GGA 130 Query: 77 NSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAEN 136 NSA TG +H+A+ G L +KLL Y + G ++ A Sbjct: 131 NSAI--------TTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQ 182 Query: 137 SGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQI 171 G EV Y +++ +P +D T + Q+ Sbjct: 183 EGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQM 217 Score = 35.0 bits (79), Expect = 0.021, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 12/116 (10%) Query: 31 IFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVN 90 + LVS +S ++ +TA+H AA+ GH + + ++L + A ++DL Sbjct: 222 VLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLL--LHGAEISQDL-------- 271 Query: 91 KTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYF 146 G T LH A+ NG+L+ ++L A +R+ G+ A AE +G Y Sbjct: 272 -WGGTPLHDAAENGELECCQILAVN-GAGLDVRDHDGYTAADLAEFNGHTHCSRYL 325 >3EHQ-A nrPDB Length = 222 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 10/104 (9%) Query: 46 ESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGK 105 ++ES LH AA G++ +R L D + VN ++K G+TAL+WA G Sbjct: 69 QAESIDNPLHEAAKRGNLSWLRECL----------DNRVGVNGLDKAGSTALYWACHGGH 118 Query: 106 LDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 D+V++L + + +NK G A+ A G ++ L K Sbjct: 119 KDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAK 162 >5CBO-A nrPDB Length = 176 Score = 43.9 bits (102), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 11/97 (11%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 111 T LH+AA GH E V +L+ A VN + TG+T LH A+ G L +V++ Sbjct: 38 TPLHLAAYWGHFEIVEVLLK----------YGADVNASDATGDTPLHLAAKWGYLGIVEV 87 Query: 112 LCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 L +Y AD ++KFG A + ++G E++ K Sbjct: 88 LL-KYGADVNAQDKFGKTAFDISIDNGNEDLAEILCK 123 >3EU9-A nrPDB Length = 240 Score = 43.1 bits (100), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 12/99 (12%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD-VVK 110 T LH AA N I+ V+Y +S+ + L +N +T LHWA+ G L VV+ Sbjct: 44 TLLHWAAINNRIDLVKYY---ISKGAIVDQLGGDLN------STPLHWATRQGHLSMVVQ 94 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 L+ +Y ADP + + G I A G + Y + K Sbjct: 95 LM--KYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK 131 Score = 29.3 bits (64), Expect = 1.1, Method: Compositional matrix adjust. Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 30/117 (25%) Query: 21 RAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYI----------- 69 R G L + + P L+ + E S +H+AA GH V Y+ Sbjct: 85 RQGHLSMVVQLMKYGADPSLI----DGEGCS-CIHLAAQFGHTSIVAYLIAKGQDVDMMD 139 Query: 70 -------LETVSRANSAED---LKAFVNEVN----KTGNTALHWASLNGKLDVVKLL 112 + R +S + L F VN NTALHWA L G V+ LL Sbjct: 140 QNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLL 196 Score = 27.7 bits (60), Expect = 3.1, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 18/25 (72%) Query: 86 VNEVNKTGNTALHWASLNGKLDVVK 110 V + +K T LHWA++N ++D+VK Sbjct: 35 VRQPDKENVTLLHWAAINNRIDLVK 59 >5AQ7-A nrPDB Length = 418 Score = 42.7 bits (99), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 11/95 (11%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 E T LH+AA GH+E V +L+ A VN + G LH A++ G + Sbjct: 78 ERGHTPLHLAAYTGHLEIVEVLLKN----------GAGVNATDVIGTAPLHLAAMWGYKE 127 Query: 108 VVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 +V++L + AD ++KFG ++ A + G E+ Sbjct: 128 IVEVLL-KAGADVDAQDKFGKRPLWLAADQGHAEI 161 Score = 32.7 bits (73), Expect = 0.10, Method: Compositional matrix adjust. Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 11/92 (11%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G + VR +L AN A+ VN ++TG T LH A+ G L +V++L Sbjct: 21 AARAGQDDEVRILL-----ANGAD-----VNTADETGFTPLHLAAWEGHLGIVEVLLKN- 69 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 AD ++ GH + A +G E+ LK Sbjct: 70 GADVNANDERGHTPLHLAAYTGHLEIVEVLLK 101 >5U0K-A nrPDB Length = 141 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 16/100 (16%) Query: 16 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS-TALHMAAANGHIETVRYILETVS 74 ++ A +GD+ +L+ + + E + + DS TALH+AAA GHIE V++++E Sbjct: 29 LLFAAYSGDVSALRRFALSAMDME------QKDYDSRTALHVAAAEGHIEVVKFLIEACK 82 Query: 75 RANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCD 114 A+D + GN L A L+VVKLL D Sbjct: 83 VNPFAKD---------RWGNIPLDDAVQFNHLEVVKLLQD 113 Score = 33.9 bits (76), Expect = 0.046, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 10/75 (13%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA +G + +R A SA D++ + + TALH A+ G ++VVK L Sbjct: 29 LLFAAYSGDVSALRRF------ALSAMDME----QKDYDSRTALHVAAAEGHIEVVKFLI 78 Query: 114 DEYEADPFIRNKFGH 128 + + +PF ++++G+ Sbjct: 79 EACKVNPFAKDRWGN 93 >5MIO-C nrPDB Length = 573 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 12/103 (11%) Query: 51 STALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 ST LH+AA GH+E V +L+ A VN V+ G+T L A++ G L +V+ Sbjct: 477 STPLHLAALIGHLEIVEVLLKH----------GADVNAVDTWGDTPLRLAAVMGHLKIVE 526 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE 153 L ++ AD ++KFG A + ++G E++ L+K ++E Sbjct: 527 ALL-KHGADVNAQDKFGKTAYDTSIDNGSEDLAE-ILQKLNLE 567 >6BY9-A nrPDB Length = 328 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 19/105 (18%) Query: 11 EDQDTIILDARAGD-LDSLKDIFTT--LVSPELLSTCKESESDSTALHMAAANGHIETVR 67 EDQ T +++A + L+++K + LV P K++E ST LH+AA GH E V+ Sbjct: 133 EDQRTPLMEAAENNHLEAVKYLIKAGALVDP------KDAEG-STCLHLAAKKGHYEVVQ 185 Query: 68 YILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 112 Y+L +N D VN + G T + WA+ +D+VKLL Sbjct: 186 YLL-----SNGQMD----VNCQDDGGWTPMIWATEYKHVDLVKLL 221 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 13/121 (10%) Query: 41 LSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWA 100 + TC SE T L AA N H+E V+Y+++ A V+ + G+T LH A Sbjct: 128 IDTC--SEDQRTPLMEAAENNHLEAVKYLIKA----------GALVDPKDAEGSTCLHLA 175 Query: 101 SLNGKLDVVKLLCDEYEADPFIRNKFGH-DAIFEAENSGKEEVETYFLKKYDVEPEDDEE 159 + G +VV+ L + D ++ G I+ E + V+ K D+ D+EE Sbjct: 176 AKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEE 235 Query: 160 D 160 + Sbjct: 236 N 236 >2DWZ-A nrPDB Length = 231 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 42/166 (25%), Positives = 71/166 (42%), Gaps = 29/166 (17%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 A +G LD LK+ +++ + L+T + + TALH A + GH E V ++L+ N Sbjct: 14 AYSGKLDELKE---RILADKSLAT-RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69 Query: 80 EDL-----------------------KAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 +D A VN VN+ G T LH+A+ + ++ +L E Sbjct: 70 DDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLL-EG 128 Query: 117 EADPFIRNKFGHDAIFEAENSGK-EEVETYFLKKYDVEPEDDEEDT 161 A+P ++ + A+ A G + V K +D E +T Sbjct: 129 GANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNT 174 Score = 30.4 bits (67), Expect = 0.51, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 11/76 (14%) Query: 50 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 109 D+TA+H AAA G+++ V +L KA N + GNT LH A +++ Sbjct: 139 DATAMHRAAAKGNLKMVHILLF----------YKASTNIQDTEGNTPLHLACDEERVEEA 188 Query: 110 KLLCDEYEADPFIRNK 125 K L + A +I NK Sbjct: 189 KFLVTQ-GASIYIENK 203 >5GP7-A nrPDB Length = 169 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 14/130 (10%) Query: 35 LVSPELLSTCKESES-DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTG 93 L +PE ++ C++++ +ST LH+AA ++E Y+LE A VN +K G Sbjct: 28 LCTPENIN-CRDTQGRNSTPLHLAAGYNNLEVAEYLLEH----------GADVNAQDKGG 76 Query: 94 NTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE 153 LH A+ G +D+ LL +Y +K+ + EA G+ ++ L + + Sbjct: 77 LIPLHNAASYGHVDIAALLI-KYNTCVNATDKWAFTPLHEAAQKGRTQLCALLL-AHGAD 134 Query: 154 PEDDEEDTQT 163 P ++ QT Sbjct: 135 PTMKNQEGQT 144 >6MWQ-A nrPDB Length = 493 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 24/114 (21%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAE-----------------------DLKAFVNE 88 T LH+AA GH+E V +L+ + N+A+ A VN Sbjct: 40 TPLHLAAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNA 99 Query: 89 VNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 ++ G T LH +++G L++V++L ++ AD ++KFG A + ++G E++ Sbjct: 100 LDLIGKTPLHLTAIDGHLEIVEVLL-KHGADVNAQDKFGKTAFDISIDNGNEDL 152 >3B7B-A nrPDB Length = 237 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 37/105 (35%), Positives = 56/105 (53%), Gaps = 19/105 (18%) Query: 11 EDQDTIILDARAGD-LDSLKDIFTT--LVSPELLSTCKESESDSTALHMAAANGHIETVR 67 EDQ T +++A + L+++K + LV P K++E ST LH+AA GH E V+ Sbjct: 42 EDQRTPLMEAAENNHLEAVKYLIKAGALVDP------KDAEG-STCLHLAAKKGHYEVVQ 94 Query: 68 YILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 112 Y+L +N D VN + G T + WA+ +D+VKLL Sbjct: 95 YLL-----SNGQMD----VNCQDDGGWTPMIWATEYKHVDLVKLL 130 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 59/133 (44%), Gaps = 14/133 (10%) Query: 30 DIFTTLVSPEL-LSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNE 88 DI LV + TC SE T L AA N H+E V+Y+++ A V+ Sbjct: 25 DICHMLVQAGANIDTC--SEDQRTPLMEAAENNHLEAVKYLIKA----------GALVDP 72 Query: 89 VNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGH-DAIFEAENSGKEEVETYFL 147 + G+T LH A+ G +VV+ L + D ++ G I+ E + V+ Sbjct: 73 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 132 Query: 148 KKYDVEPEDDEED 160 K D+ D+EE+ Sbjct: 133 KGSDINIRDNEEN 145 >5AQB-A nrPDB Length = 428 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 50/91 (54%), Gaps = 11/91 (12%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 111 T LH+AA +GH+E V +L+ A VN ++ G T LH A++ G L++V++ Sbjct: 81 TPLHLAAFSGHLEIVEVLLK----------YGADVNADDQAGFTPLHLAAIFGHLEIVEV 130 Query: 112 LCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 L + AD ++KFG A ++G E++ Sbjct: 131 LL-KNGADVNAQDKFGKTPRDLAIDNGNEDI 160 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 13/110 (11%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 E T LH+AA GH+E V +L+ N A+ VN + G T LH A+ +G L+ Sbjct: 45 EVGWTPLHLAAW-GHLEIVECLLK-----NGAD-----VNAADIDGYTPLHLAAFSGHLE 93 Query: 108 VVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK-YDVEPED 156 +V++L +Y AD ++ G + A G E+ LK DV +D Sbjct: 94 IVEVLL-KYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQD 142 Score = 28.1 bits (61), Expect = 2.3, Method: Compositional matrix adjust. Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 10/65 (15%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 ++ T LH+AA GH+E V +L+ N A+ VN +K G T A NG D Sbjct: 110 QAGFTPLHLAAIFGHLEIVEVLLK-----NGAD-----VNAQDKFGKTPRDLAIDNGNED 159 Query: 108 VVKLL 112 + ++L Sbjct: 160 IAEVL 164 >5AQ9-A nrPDB Length = 422 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/121 (26%), Positives = 61/121 (50%), Gaps = 24/121 (19%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAE-------DLKAF---------------- 85 + +T LH+AA +GH+E V +L+ + ++++ L A+ Sbjct: 46 TGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGAD 105 Query: 86 VNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETY 145 VN ++ G T LH A+ G L++V++L ++ AD ++KFG A+++G ++V T Sbjct: 106 VNAMDSDGMTPLHLAAKWGYLEIVEVLL-KHGADVNAQDKFGKTPFDLADDNGNDDVGTL 164 Query: 146 F 146 Sbjct: 165 L 165 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 11/92 (11%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G + VR ++ AN A+ VN + TG T LH A+ +G L++V++L ++ Sbjct: 21 AARAGQDDEVRILM-----ANGAD-----VNAADNTGTTPLHLAAYSGHLEIVEVLL-KH 69 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 AD + FG+ + A G E+ LK Sbjct: 70 GADVDASDVFGYTPLHLAAYWGHLEIVEVLLK 101 >4NIK-A nrPDB Length = 230 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 41/166 (24%), Positives = 74/166 (44%), Gaps = 29/166 (17%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 A +G L+ LK+ ++++ + L+T + + TALH A + GH E V ++L+ N Sbjct: 18 AYSGKLEELKE---SILADKSLAT-RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 73 Query: 80 ED-----------------LKAF------VNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 +D +KA VN VN+ G T LH+A+ + ++ +L E Sbjct: 74 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL-EG 132 Query: 117 EADPFIRNKFGHDAIFEAENSGK-EEVETYFLKKYDVEPEDDEEDT 161 A+P ++ + A+ A G + + K +D E +T Sbjct: 133 GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNT 178 Score = 30.4 bits (67), Expect = 0.52, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 50 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 109 ++TA+H AAA G+++ + +L KA N + GNT LH A +++ Sbjct: 143 EATAMHRAAAKGNLKMIHILLY----------YKASTNIQDTEGNTPLHLACDEERVEEA 192 Query: 110 KLLCDEYEADPFIRNK 125 KLL + A +I NK Sbjct: 193 KLLVSQ-GASIYIENK 207 >6FES-A nrPDB Length = 367 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 11/95 (11%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 E T LH+AA GH+E V +L+ A VN + G LH A++ G + Sbjct: 70 ERGHTPLHLAAYTGHLEIVEVLLKN----------GAGVNATDVIGTAPLHLAAMWGHEE 119 Query: 108 VVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 +V++L + AD ++KFG A ++G E V Sbjct: 120 IVEVLL-KNGADARAQDKFGKTPEDLARDNGYESV 153 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 37/126 (29%), Positives = 56/126 (44%), Gaps = 20/126 (15%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 E+ T LH+AA GH+ V +L+ N A+ VN ++ G+T LH A+ G L+ Sbjct: 37 ETGFTPLHLAAWEGHLGIVEVLLK-----NGAD-----VNANDERGHTPLHLAAYTGHLE 86 Query: 108 VVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK---------KYDVEPEDDE 158 +V++L + A + G + A G EE+ LK K+ PED Sbjct: 87 IVEVLL-KNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLA 145 Query: 159 EDTQTE 164 D E Sbjct: 146 RDNGYE 151 Score = 33.1 bits (74), Expect = 0.093, Method: Compositional matrix adjust. Identities = 30/92 (32%), Positives = 45/92 (48%), Gaps = 11/92 (11%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G + VR +L AN A+ VN ++TG T LH A+ G L +V++L + Sbjct: 13 AARAGQDDEVRILL-----ANGAD-----VNTADETGFTPLHLAAWEGHLGIVEVLL-KN 61 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 AD ++ GH + A +G E+ LK Sbjct: 62 GADVNANDERGHTPLHLAAYTGHLEIVEVLLK 93 >5UQE-A nrPDB Length = 520 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 31/104 (29%), Positives = 50/104 (48%), Gaps = 17/104 (16%) Query: 16 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS-TALHMAAANGHIETVRYILETVS 74 ++ A GD+ +L+ + + E + + DS TALH+AAA GH+E V+++LE Sbjct: 421 LLFAAYTGDVSALRRFALSAMDME------QRDYDSRTALHVAAAEGHVEVVKFLLEACK 474 Query: 75 RANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEA 118 +D + NT + A G DV K+L EY+ Sbjct: 475 VNPFPKD---------RWNNTPMDEALHFGHHDVFKIL-QEYQV 508 Score = 35.4 bits (80), Expect = 0.014, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 13/109 (11%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + +R A SA D++ + + TALH A+ G ++VVK L Sbjct: 421 LLFAAYTGDVSALRRF------ALSAMDME----QRDYDSRTALHVAAAEGHVEVVKFLL 470 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE--PEDDEED 160 + + +PF ++++ + + EA + G +V L++Y V+ P+ D ++ Sbjct: 471 EACKVNPFPKDRWNNTPMDEALHFGHHDVFK-ILQEYQVQYTPQGDSDN 518 >3LJN-A nrPDB Length = 364 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 21/106 (19%) Query: 9 DQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRY 68 D E+ + I + AR G D ++ + T VSP + ++ TALH+A G ++T +Y Sbjct: 17 DDENMEKIHVAARKGQTDEVRRLIETGVSPTI-----QNRFGCTALHLACKFGCVDTAKY 71 Query: 69 ILETVSRANSAEDLKAFVNEVNKT--GNTALHWASLNGKLDVVKLL 112 + A V EV+ G +H A + K D+V L Sbjct: 72 L--------------ASVGEVHSLWHGQKPIHLAVMANKTDLVVAL 103 Score = 27.3 bits (59), Expect = 4.3, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 12/73 (16%) Query: 41 LSTCKESESDSTALHMAAANGHIETVRYILET-VSRANSAEDLKAFVNEVNKTGNTALHW 99 L+ K + + +H+AA G + VR ++ET VS N+ G TALH Sbjct: 11 LNRIKSDDENMEKIHVAARKGQTDEVRRLIETGVSPTIQ-----------NRFGCTALHL 59 Query: 100 ASLNGKLDVVKLL 112 A G +D K L Sbjct: 60 ACKFGCVDTAKYL 72 Score = 26.6 bits (57), Expect = 7.5, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 5/61 (8%) Query: 42 STCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWAS 101 S + ++D T L A + E + +++TV +S ++ NK GN+ LHWA Sbjct: 165 SPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLR-----LDYANKQGNSHLHWAI 219 Query: 102 L 102 L Sbjct: 220 L 220 >5D68-A nrPDB Length = 486 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 17/153 (11%) Query: 50 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 109 D LH +A G E + +L + VN+++ +H+A GK++ Sbjct: 38 DDFPLHRSACEGDSELLSRLLSE----------RFSVNQLDSDHWAPIHYACWYGKVEAT 87 Query: 110 KLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSV 169 ++L ++ + +P + N + A G E+ L PE D T +G++ + Sbjct: 88 RILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN----HPETDRHITDQQGRSPL 143 Query: 170 QIT---KGTEIEQVTKEATEALREETEKLNINK 199 I K E+ K EA+ + EK+ I + Sbjct: 144 NICEENKQNNWEEAAKLLKEAINKPYEKVRIYR 176 Score = 30.4 bits (67), Expect = 0.50, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 10/85 (11%) Query: 48 ESDSTA-LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKL 106 +SD A +H A G +E R +LE + N N +N ++ LH+A+ G Sbjct: 68 DSDHWAPIHYACWYGKVEATRILLEK-GKCNP--------NLLNGQLSSPLHFAAGGGHA 118 Query: 107 DVVKLLCDEYEADPFIRNKFGHDAI 131 ++V++L + E D I ++ G + Sbjct: 119 EIVQILLNHPETDRHITDQQGRSPL 143 >5JHQ-A nrPDB Length = 482 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 11/86 (12%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 LH A + GH E V +L + N+ ++ T LH A++ GK+DV +L Sbjct: 86 LHNACSFGHAEVVSLLLCQGADPNARDNWN----------YTPLHEAAIKGKIDVCIVLL 135 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGK 139 ++ ADP IRN G A+ A+ S K Sbjct: 136 -QHGADPNIRNTDGKSALDLADPSAK 160 Score = 36.6 bits (83), Expect = 0.008, Method: Compositional matrix adjust. Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 15/105 (14%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 111 T LH+AA H + ++E + + A +N ++ G TALH A+L G L +L Sbjct: 393 TPLHVAAERAHND----VMEVLHKHG------AKMNALDTLGQTALHRAALAGHLQTCRL 442 Query: 112 LCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPED 156 L Y +DP I + G F A G E V+ + + D Sbjct: 443 LL-SYGSDPSIISLQG----FTAAQMGNEAVQQILSESTPIRTSD 482 Score = 29.6 bits (65), Expect = 0.84, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 16/142 (11%) Query: 45 KESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNG 104 K+ +S TALH A A+ H + + + E + R A VNE NK T LH A+ Sbjct: 350 KQPQSHETALHCAVASLHPKR-KQVTELLLRKG------ANVNEKNKDFMTPLHVAAERA 402 Query: 105 KLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTE 164 DV+++L ++ A + G A+ A +G + L Y +P + Sbjct: 403 HNDVMEVL-HKHGAKMNALDTLGQTALHRAALAGHLQT-CRLLLSYGSDP----SIISLQ 456 Query: 165 GKNSVQITKGTE-IEQVTKEAT 185 G + Q+ G E ++Q+ E+T Sbjct: 457 GFTAAQM--GNEAVQQILSEST 476 >5U0J-A nrPDB Length = 140 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 17/103 (16%) Query: 16 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS-TALHMAAANGHIETVRYILETVS 74 ++ A GD+ +L+ + + E + + DS TALH+AAA GH+E V+++LE Sbjct: 28 LLFAAYTGDVSALRRFALSAMDME------QRDYDSRTALHVAAAEGHVEVVKFLLEACK 81 Query: 75 RANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYE 117 +D + NT + A G DV K+L EY+ Sbjct: 82 VNPFPKD---------RWNNTPMDEALHFGHHDVFKIL-QEYQ 114 Score = 36.6 bits (83), Expect = 0.007, Method: Compositional matrix adjust. Identities = 25/78 (32%), Positives = 45/78 (57%), Gaps = 6/78 (7%) Query: 95 TALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE- 153 TALH A+ G ++VVK L + + +PF ++++ + + EA + G +V L++Y V+ Sbjct: 59 TALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFK-ILQEYQVQY 117 Query: 154 -PEDDEED---TQTEGKN 167 P+ D ++ QT KN Sbjct: 118 TPQGDSDNGKENQTVHKN 135 >1WG0-A nrPDB Length = 243 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 13/132 (9%) Query: 22 AGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAED 81 G+L+ +K ++ + P+L K + T LH+A E ++++E Sbjct: 82 VGNLEVVKSLYDRPLKPDL---NKITNQGVTCLHLAVGKKWFEVSQFLIEN--------- 129 Query: 82 LKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEE 141 A V +K LH A+ G L +++LLC ++ ++K G +F A G + Sbjct: 130 -GASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGD 188 Query: 142 VETYFLKKYDVE 153 ++KY E Sbjct: 189 AAVLLVEKYGAE 200 >5HKP-A nrPDB Length = 351 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 30/92 (32%), Positives = 44/92 (47%), Gaps = 15/92 (16%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 111 T LH+AA H + ++E + + A +N ++ G TALH A+L G L +L Sbjct: 249 TPLHVAAERAHND----VMEVLHKHG------AKMNALDSLGQTALHRAALAGHLQTCRL 298 Query: 112 LCDEYEADPFIRNKFGHDAIFEAENSGKEEVE 143 L Y +DP I + G F A G E V+ Sbjct: 299 LLS-YGSDPSIISLQG----FTAAQMGNEAVQ 325 Score = 30.0 bits (66), Expect = 0.62, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 64/142 (45%), Gaps = 16/142 (11%) Query: 45 KESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNG 104 K+ +S TALH A A+ H + + + E + R A VNE NK T LH A+ Sbjct: 206 KQPQSHETALHCAVASLHPKR-KQVAELLLRKG------ANVNEKNKDFMTPLHVAAERA 258 Query: 105 KLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTE 164 DV+++L ++ A + G A+ A +G + L Y +P + Sbjct: 259 HNDVMEVL-HKHGAKMNALDSLGQTALHRAALAGHLQT-CRLLLSYGSDP----SIISLQ 312 Query: 165 GKNSVQITKGTE-IEQVTKEAT 185 G + Q+ G E ++Q+ E+T Sbjct: 313 GFTAAQM--GNEAVQQILSEST 332 >4Z68-A nrPDB Length = 155 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 30/132 (22%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESES-DSTALHMAAANGHIETVRYILE------- 71 A+AGD++++K + T C++ E ST LH AA + V Y+L+ Sbjct: 11 AKAGDVETVKKLCTVQSV-----NCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65 Query: 72 -------------TVSRANSAEDL---KAFVNEVNKTGNTALHWASLNGKLDVVKLLCDE 115 + AE L A VN + T LH A+ GK ++ KLL + Sbjct: 66 KDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLL-Q 124 Query: 116 YEADPFIRNKFG 127 + ADP +N+ G Sbjct: 125 HGADPTKKNRDG 136 >4OAU-C nrPDB Length = 699 Score = 36.2 bits (82), Expect = 0.009, Method: Compositional matrix adjust. Identities = 24/83 (28%), Positives = 41/83 (49%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 111 TA AA G ++ ++++ + + N K + K G TAL A+ G ++V+K+ Sbjct: 107 TAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKI 166 Query: 112 LCDEYEADPFIRNKFGHDAIFEA 134 L DE AD + G +A+ A Sbjct: 167 LLDEMGADVNACDNMGRNALIHA 189 Score = 26.9 bits (58), Expect = 6.1, Method: Compositional matrix adjust. Identities = 35/152 (23%), Positives = 65/152 (42%), Gaps = 17/152 (11%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESE-----SDSTALHMAAANGHIETVRYILETVS 74 A G + +LK ++ + L KE + +TAL AA GH+E ++ +L Sbjct: 113 AVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL---- 168 Query: 75 RANSAEDLKAFVNEVNKTGNTALHWASL---NGKLDVVKLLCDEYEADPFIRNKFGHDAI 131 +++ A VN + G AL A L + ++ + L ++ AD +R + G + Sbjct: 169 -----DEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPL 223 Query: 132 FEAENSGKEEVETYFLKKYDVEPEDDEEDTQT 163 A + L++ +E D + D +T Sbjct: 224 ILAVEKKHLGLVQRLLEQEHIEINDTDSDGKT 255 >5H76-A nrPDB Length = 201 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 8/93 (8%) Query: 62 HIETVRYILETVSRANSAEDLKAF------VNEVNKTGNTALHWASLNGKLDVVKLLCDE 115 H++ R +LE +RA ++++ VN + TG T LH A+ +G L++V++L + Sbjct: 3 HMDLGRKLLEA-ARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLL-K 60 Query: 116 YEADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 + AD + FG+ + A G E+ LK Sbjct: 61 HGADVDASDVFGYTPLHLAAYWGHLEIVEVLLK 93 Score = 33.9 bits (76), Expect = 0.046, Method: Compositional matrix adjust. Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 11/106 (10%) Query: 51 STALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 +T LH+AA +GH+E V +L+ A V+ + G T LH A+ G L++V+ Sbjct: 40 TTPLHLAAYSGHLEIVEVLLKH----------GADVDASDVFGYTPLHLAAYWGHLEIVE 89 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPED 156 +L AD + G + A G E+ LK V +D Sbjct: 90 VLLKN-GADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGAVNAQD 134 >5AQA-A nrPDB Length = 418 Score = 35.8 bits (81), Expect = 0.013, Method: Compositional matrix adjust. Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 24/117 (20%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAE-------DLKAF---------------- 85 + +T LH+AA +GH+E V +L+ + ++++ L A+ Sbjct: 46 TGTTPLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGAD 105 Query: 86 VNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 VN ++ G T LH A+ G ++V++L + AD ++KFG ++ A + G E+ Sbjct: 106 VNAMDSDGMTPLHLAAKWGYKEIVEVLL-KAGADVDAQDKFGKRPLWLAADQGHAEI 161 Score = 35.4 bits (80), Expect = 0.015, Method: Compositional matrix adjust. Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 11/92 (11%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G + VR ++ AN A+ VN + TG T LH A+ +G L++V++L ++ Sbjct: 21 AARAGQDDEVRILM-----ANGAD-----VNAADNTGTTPLHLAAYSGHLEIVEVLL-KH 69 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 AD + FG+ + A G E+ LK Sbjct: 70 GADVDASDVFGYTPLHLAAYWGHLEIVEVLLK 101 >1G3N-B nrPDB Length = 168 Score = 33.1 bits (74), Expect = 0.088, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 14/93 (15%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 ARAG LD+L+ TL+ + +++E + LH+AA GH+ V ++++ + Sbjct: 78 ARAGFLDTLQ----TLLEFQADVNIEDNEGN-LPLHLAAKEGHLRVVEFLVKHTA----- 127 Query: 80 EDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 112 + V N G+TA A L G+ +VV L+ Sbjct: 128 ----SNVGHRNHKGDTACDLARLYGRNEVVSLM 156 Score = 30.8 bits (68), Expect = 0.39, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 10/89 (11%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 +H AA G ++T++ +LE +A VN + GN LH A+ G L VV+ L Sbjct: 74 IHDAARAGFLDTLQTLLE----------FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEV 142 ++ RN G A A G+ EV Sbjct: 124 KHTASNVGHRNHKGDTACDLARLYGRNEV 152 >6EMK-G nrPDB Length = 426 Score = 31.6 bits (70), Expect = 0.21, Method: Compositional matrix adjust. Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 13/74 (17%) Query: 39 ELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALH 98 EL+ T K +T +H+A GH +T+ +L+ R F+N + G +H Sbjct: 68 ELIKTFK----GNTCVHLALMKGHEQTLHLLLQQFPR---------FINHRGENGRAPIH 114 Query: 99 WASLNGKLDVVKLL 112 A +N + LL Sbjct: 115 IACMNDYYQCLSLL 128 >3ZKJ-A nrPDB Length = 261 Score = 31.6 bits (70), Expect = 0.22, Method: Compositional matrix adjust. Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 12/110 (10%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDV 108 SD + +H AA +GH ++R + +S+ + VN + + LH A L G L Sbjct: 2 SDWSPMHEAAIHGHQLSLRNL---ISQGWA-------VNIITADHVSPLHEACLGGHLSC 51 Query: 109 VKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK-YDVEPEDD 157 VK+L + + H +F A SG + L+ V+PE D Sbjct: 52 VKILLKHGAQVNGVTADW-HTPLFNACVSGSWDCVNLLLQHGASVQPESD 100 >4O1O-A nrPDB Length = 717 Score = 31.2 bits (69), Expect = 0.29, Method: Compositional matrix adjust. Identities = 34/135 (25%), Positives = 58/135 (42%), Gaps = 16/135 (11%) Query: 51 STALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLN---GKLD 107 +TAL AA GH+ V +L +KA V+ + G AL +A LN GK Sbjct: 152 ATALMDAAEKGHVGVVTILLHA---------MKAEVDARDNMGRNALVYALLNPDDGKAK 202 Query: 108 VVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKN 167 + L ++ AD +R + + A ++ L++ +E DT EGK Sbjct: 203 AITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEV----NDTDREGKT 258 Query: 168 SVQITKGTEIEQVTK 182 ++ + +E++ K Sbjct: 259 ALLLAVELRLEEIAK 273 >3FY4-A nrPDB Length = 537 Score = 31.2 bits (69), Expect = 0.32, Method: Compositional matrix adjust. Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 16/83 (19%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 ESD +A ++ + +R++LE++ +S+ + K G+ L + G++ Sbjct: 45 ESDPSAFSPGSSRAGVNRIRFLLESLKDLDSS---------LKKLGSRLLVFKGEPGEVL 95 Query: 108 V-------VKLLCDEYEADPFIR 123 V VK LC EY+ DP+ + Sbjct: 96 VRCLQEWKVKRLCFEYDTDPYYQ 118 >4OT9-A nrPDB Length = 359 Score = 31.2 bits (69), Expect = 0.35, Method: Compositional matrix adjust. Identities = 44/156 (28%), Positives = 63/156 (40%), Gaps = 16/156 (10%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTA--LHMAAANGHIETVRYILE 71 D +LD R GD + +PELL +S + + LHM G Y + Sbjct: 146 DPALLD-RHGDSAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEG-----LYPVH 199 Query: 72 TVSRANSAEDLKAFVN---EVNKT----GNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 RA S E L V+ EV T G TALH A+ +L +V L + A+ R Sbjct: 200 LAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNART 259 Query: 125 KFGHDAIFEAENSGKEEVETYFLKK-YDVEPEDDEE 159 G+ + A G + LK D+ E++E Sbjct: 260 FAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEP 295 >6DMR-A nrPDB Length = 730 Score = 30.0 bits (66), Expect = 0.68, Method: Composition-based stats. Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 7/62 (11%) Query: 52 TALHMAAANGHIETVRYILETVSR-ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 TALH+AA ++E ++E A + FV G TALH A +N L++V+ Sbjct: 81 TALHVAALYDNLEAATLLMEAAPELAKEPALCEPFV------GQTALHIAVMNQNLNLVR 134 Query: 111 LL 112 L Sbjct: 135 AL 136 Score = 26.9 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 4/83 (4%) Query: 52 TALHMAAANGHIETVRYIL---ETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDV 108 TALH+A N ++ VR +L +VS + + + + G L +A+ G ++ Sbjct: 119 TALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEI 178 Query: 109 VKLLCDEYEADPFIRNKFGHDAI 131 V+LL E+ AD ++ G+ + Sbjct: 179 VRLLI-EHGADIRAQDSLGNTVL 200 >6AUN-A nrPDB Length = 752 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 11/65 (16%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK- 110 TA H A + + ++ + + S A +N+VNK G T LH A GK ++V+ Sbjct: 188 TAFHYAVQGDNSQVLQLLGKNAS---------AGLNQVNKQGLTPLHLACQMGKQEMVRV 238 Query: 111 -LLCD 114 LLC+ Sbjct: 239 LLLCN 243 Score = 28.9 bits (63), Expect = 1.7, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 41/97 (42%), Gaps = 9/97 (9%) Query: 46 ESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGK 105 E+E T LH+A G E ++E V ++ D+ + G TA H+A Sbjct: 148 ENEEGCTPLHLACRKGDSEI---LVELVQYCHAQMDV------TDNKGETAFHYAVQGDN 198 Query: 106 LDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 V++LL A NK G + A GK+E+ Sbjct: 199 SQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGKQEM 235 Score = 26.6 bits (57), Expect = 7.1, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAF------VNEVNKTGNTALHWASLNGKLD 107 + M ++ H + RY + A +AE + V+ + GNTALH A + + D Sbjct: 272 ISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFD 331 Query: 108 VVKLL 112 V +L Sbjct: 332 CVMVL 336 >2B0O-E nrPDB Length = 301 Score = 28.1 bits (61), Expect = 2.4, Method: Compositional matrix adjust. Identities = 12/20 (60%), Positives = 16/20 (80%) Query: 93 GNTALHWASLNGKLDVVKLL 112 GNTALH+A+L + D +KLL Sbjct: 226 GNTALHYAALYNQPDCLKLL 245 >3LVQ-E nrPDB Length = 497 Score = 28.1 bits (61), Expect = 2.6, Method: Compositional matrix adjust. Identities = 12/20 (60%), Positives = 16/20 (80%) Query: 93 GNTALHWASLNGKLDVVKLL 112 GNTALH+A+L + D +KLL Sbjct: 207 GNTALHYAALYNQPDCLKLL 226 >6BOA-A nrPDB Length = 742 Score = 28.1 bits (61), Expect = 2.8, Method: Composition-based stats. Identities = 26/102 (25%), Positives = 50/102 (49%), Gaps = 13/102 (12%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILET 72 + ++L A+ D+ +L L+ E + TALH+AA ++E ++E Sbjct: 46 ESPLLLAAKDNDVQAL----NKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLME- 100 Query: 73 VSRANSAEDL--KAFVNEVNKTGNTALHWASLNGKLDVVKLL 112 +A +L + +E+ + G TALH A +N +++V+ L Sbjct: 101 -----AAPELVFEPMTSELYE-GQTALHIAVVNQNMNLVRAL 136 >6E2G-A nrPDB Length = 727 Score = 27.7 bits (60), Expect = 3.4, Method: Composition-based stats. Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 37 SPELLSTCKESE--SDSTALHMAAANGHIETVRYIL---ETVSRANSAEDLKAFVNEVNK 91 +PEL+ SE TALH+A N ++ VR +L +VS + + + Sbjct: 102 APELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIY 161 Query: 92 TGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAI 131 G L +A+ G ++V+LL E+ AD ++ G+ + Sbjct: 162 YGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVL 200 >1YCD-A nrPDB Length = 243 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 19/29 (65%) Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETY 145 +A P +R+K+ +D +A+N KE+V Y Sbjct: 184 QAVPSVRSKYLYDIYLKAQNGNKEKVLAY 212 >1D9S-A nrPDB Length = 136 Score = 27.3 bits (59), Expect = 4.9, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 15/90 (16%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDV 108 S L AAA G +ETVR +LE A N +N+ G + + G V Sbjct: 11 SSDAGLATAAARGQVETVRQLLEA----------GADPNALNRFGRRPIQ-VMMMGSAQV 59 Query: 109 VKLL----CDEYEADPFIRNKFGHDAIFEA 134 +LL + ADP + HDA E Sbjct: 60 AELLLLHGAEPNCADPATLTRPVHDAAREG 89 >3G2U-A nrPDB Length = 149 Score = 26.9 bits (58), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 3/53 (5%) Query: 76 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGH 128 A E L+A +N N L WAS+NG + L +++E P H Sbjct: 6 AMEPETLEARINRATNPLNKELDWASING---FCEQLNEDFEGPPLATRLLAH 55 >5EJK-A nrPDB Length = 270 Score = 26.9 bits (58), Expect = 6.1, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 6/49 (12%) Query: 45 KESESDSTALHMA------AANGHIETVRYILETVSRANSAEDLKAFVN 87 +E++ TALH+ A+N ++ R +++T NSA L+A VN Sbjct: 3 REAKDLHTALHIGPRALSKASNISMQQAREVVQTCPHCNSAPALEAGVN 51 >4UDE-A nrPDB Length = 110 Score = 26.6 bits (57), Expect = 7.6, Method: Compositional matrix adjust. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 107 DVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVE 143 DV++ L D Y D + K+G + AE +E+E Sbjct: 48 DVIRTLVDIYRVDLLVGEKYGIKSAVRAEKRRLDELE 84 >2RFA-A nrPDB Length = 232 Score = 26.2 bits (56), Expect = 9.7, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 37 SPELLSTCKESE--SDSTALHMAAANGHIETVRYIL---ETVSRANSAEDLKAFVNEVNK 91 +PEL+ SE TALH+A N ++ VR +L +VS + + + Sbjct: 60 APELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIY 119 Query: 92 TGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAI 131 G L +A+ G ++V+LL E+ AD ++ G+ + Sbjct: 120 YGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVL 158 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4BSZ-B nrPDB 267 3e-72 5ET1-A nrPDB 153 4e-38 2DWZ-A nrPDB 135 1e-32 5GP7-A nrPDB 133 5e-32 5AQ9-A nrPDB 132 9e-32 4NIK-A nrPDB 131 3e-31 6MWQ-A nrPDB 128 1e-30 5AQB-A nrPDB 125 1e-29 5AQ7-A nrPDB 123 5e-29 5CBO-A nrPDB 122 1e-28 5MIO-C nrPDB 122 1e-28 6FES-A nrPDB 117 4e-27 3EU9-A nrPDB 113 7e-26 3EHQ-A nrPDB 111 2e-25 6BY9-A nrPDB 109 6e-25 3B7B-A nrPDB 108 2e-24 5U0K-A nrPDB 90 5e-19 Sequences not found previously or not previously below threshold: 5AQA-A nrPDB 126 7e-30 4Z68-A nrPDB 115 1e-26 5H76-A nrPDB 114 3e-26 5JHQ-A nrPDB 111 3e-25 5HKP-A nrPDB 105 1e-23 1WG0-A nrPDB 86 7e-18 5UQE-A nrPDB 83 6e-17 4OAU-C nrPDB 83 9e-17 5U0J-A nrPDB 82 2e-16 5D68-A nrPDB 81 2e-16 1BLX-B nrPDB 78 3e-15 1BD8-A nrPDB 78 3e-15 4O1O-A nrPDB 74 4e-14 6AUN-A nrPDB 71 3e-13 1G3N-B nrPDB 71 4e-13 4OT9-A nrPDB 70 8e-13 3T9K-A nrPDB 66 1e-11 3ZKJ-A nrPDB 65 2e-11 2KXP-C nrPDB 65 2e-11 6EMK-G nrPDB 63 8e-11 5DND-A nrPDB 58 2e-09 2RFA-A nrPDB 56 9e-09 2A5E-A nrPDB 56 1e-08 1D9S-A nrPDB 55 2e-08 6E2G-A nrPDB 54 3e-08 6DMR-A nrPDB 54 3e-08 5IRX-A nrPDB 54 4e-08 2NYJ-A nrPDB 54 4e-08 6DVZ-A nrPDB 54 5e-08 3LVQ-E nrPDB 54 6e-08 2B0O-E nrPDB 54 6e-08 4N5Q-A nrPDB 52 2e-07 6BOA-A nrPDB 51 3e-07 3LJN-A nrPDB 48 2e-06 1DCQ-A nrPDB 47 4e-06 6CV9-A nrPDB 46 1e-05 3DEO-A nrPDB 44 3e-05 6MHW-A nrPDB 44 4e-05 3UI2-A nrPDB 44 5e-05 6CUD-A nrPDB 43 7e-05 6DJS-A nrPDB 43 1e-04 6C8G-A nrPDB 43 1e-04 6BBJ-A nrPDB 43 1e-04 3W9G-A nrPDB 41 4e-04 5UIL-A nrPDB 41 5e-04 5AN8-A nrPDB 39 0.001 6OO7-A nrPDB 39 0.002 6BO5-A nrPDB 38 0.003 5HI9-A nrPDB 37 0.006 2ETB-A nrPDB 37 0.006 6G1K-A nrPDB 37 0.007 2F37-A nrPDB 36 0.008 4XD0-A nrPDB 34 0.062 5Z6P-A nrPDB 31 0.47 1GO3-E nrPDB 29 1.4 2YCL-A nrPDB 28 3.3 >4BSZ-B nrPDB Length = 202 Score = 267 bits (681), Expect = 3e-72, Method: Composition-based stats. Identities = 200/200 (100%), Positives = 200/200 (100%) Query: 1 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN 60 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN Sbjct: 3 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN 62 Query: 61 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP 120 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP Sbjct: 63 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP 122 Query: 121 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQV 180 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQV Sbjct: 123 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQV 182 Query: 181 TKEATEALREETEKLNINKD 200 TKEATEALREETEKLNINKD Sbjct: 183 TKEATEALREETEKLNINKD 202 >5ET1-A nrPDB Length = 353 Score = 153 bits (387), Expect = 4e-38, Method: Composition-based stats. Identities = 38/156 (24%), Positives = 61/156 (39%), Gaps = 19/156 (12%) Query: 19 DARAGDLDSLKDIFTTLVSPELLSTCKESESD---STALHMAAANGHIETVRYILETVSR 75 A G L L+ + T C+ E D +T LH+AA GH + V+++L Sbjct: 78 AAATGYLSCLQWLLTQ-------GGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQG-- 128 Query: 76 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAE 135 A TG +H+A+ G L +KLL Y + G ++ A Sbjct: 129 -------GANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLAC 181 Query: 136 NSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQI 171 G EV Y +++ +P +D T + Q+ Sbjct: 182 QEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQM 217 Score = 78.0 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 37/163 (22%), Positives = 65/163 (39%), Gaps = 19/163 (11%) Query: 8 LDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 L +D T + A G L LVS +S ++ +TA+H AA+ GH + + Sbjct: 202 LRAQDGMTPLHAAAQMGHNPVLVW----LVSFADVSFSEQDHDGATAMHFAASRGHTKVL 257 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKF 126 ++L + + G T LH A+ NG+L+ ++L A +R+ Sbjct: 258 SWLLLHGAEI-----------SQDLWGGTPLHDAAENGELECCQILAVN-GAGLDVRDHD 305 Query: 127 GHDAIFEAENSGKEEVETYF--LKKYDVEPEDDEEDTQTEGKN 167 G+ A AE +G Y ++ +E D + + Sbjct: 306 GYTAADLAEFNGHTHCSRYLRTVQTLSLEHRVLSRDQSMDLEA 348 Score = 48.3 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 39/114 (34%), Gaps = 9/114 (7%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G ++ +R + S + +H A+ +GKL ++ L +E Sbjct: 10 AARRGDLDVLRSLHAAGLLGPSLR---------DSLDALPVHHAARSGKLHCLRYLVEEV 60 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 R + G +A +G + L + ++ + T + + Sbjct: 61 ALPAVSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAAR 114 >2DWZ-A nrPDB Length = 231 Score = 135 bits (339), Expect = 1e-32, Method: Composition-based stats. Identities = 48/200 (24%), Positives = 84/200 (42%), Gaps = 32/200 (16%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 A +G LD LK+ +++ + L+T + + TALH A + GH E V ++L+ N Sbjct: 14 AYSGKLDELKE---RILADKSLAT-RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 69 Query: 80 EDL-----------------------KAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 +D A VN VN+ G T LH+A+ + ++ +L E Sbjct: 70 DDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLL-EG 128 Query: 117 EADPFIRNKFGHDAIFEAENSGK-EEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGT 175 A+P ++ + A+ A G + V K +D E + T + + Sbjct: 129 GANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGN--TPLHLACDEERVE 186 Query: 176 EIE-QVTKEATEALREETEK 194 E + VT+ A+ + + EK Sbjct: 187 EAKFLVTQGASIYIENKEEK 206 >5GP7-A nrPDB Length = 169 Score = 133 bits (334), Expect = 5e-32, Method: Composition-based stats. Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 15/152 (9%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 D +LDA L + L +PE ++ +ST LH+AA ++E Y+LE Sbjct: 10 DAALLDAA--KKGCLARV-QKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEH- 65 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 A VN +K G LH A+ G +D+ LL +Y +K+ + E Sbjct: 66 ---------GADVNAQDKGGLIPLHNAASYGHVDIAALLI-KYNTCVNATDKWAFTPLHE 115 Query: 134 AENSGKEEVETYFLKKYDVEPEDDEEDTQTEG 165 A G+ ++ L + +P ++ QT Sbjct: 116 AAQKGRTQLCALLLA-HGADPTMKNQEGQTPL 146 Score = 47.2 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 29/79 (36%), Gaps = 5/79 (6%) Query: 93 GNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGH--DAIFEAENSGKEEVETYFLKKY 150 G+ AL A+ G L V+ LC + R+ G + A EV Y L ++ Sbjct: 9 GDAALLDAAKKGCLARVQKLCT--PENINCRDTQGRNSTPLHLAAGYNNLEVAEYLL-EH 65 Query: 151 DVEPEDDEEDTQTEGKNSV 169 + ++ N+ Sbjct: 66 GADVNAQDKGGLIPLHNAA 84 >5AQ9-A nrPDB Length = 422 Score = 132 bits (332), Expect = 9e-32, Method: Composition-based stats. Identities = 36/163 (22%), Positives = 70/163 (42%), Gaps = 29/163 (17%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ ARAG D ++ + + +T LH+AA +GH+E V +L+ Sbjct: 16 RKLLEAARAGQDDEVRILMANGADVNAA-----DNTGTTPLHLAAYSGHLEIVEVLLKHG 70 Query: 74 SRANSAE-----------------------DLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 + ++++ A VN ++ G T LH A+ G L++V+ Sbjct: 71 ADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVE 130 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE 153 +L ++ AD ++KFG A+++G ++V T + Sbjct: 131 VLL-KHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAAD 172 Score = 100 bits (248), Expect = 5e-22, Method: Composition-based stats. Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 12/117 (10%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + VR ++ A VN + TG T LH A+ +G L++V++L Sbjct: 18 LLEAARAGQDDEVRILMA----------NGADVNAADNTGTTPLHLAAYSGHLEIVEVLL 67 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 ++ AD + FG+ + A G E+ L K + + D T + + Sbjct: 68 -KHGADVDASDVFGYTPLHLAAYWGHLEIVEVLL-KNGADVNAMDSDGMTPLHLAAK 122 >4NIK-A nrPDB Length = 230 Score = 131 bits (328), Expect = 3e-31, Method: Composition-based stats. Identities = 43/199 (21%), Positives = 81/199 (40%), Gaps = 31/199 (15%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 A +G L+ LK+ ++++ + L+T + + TALH A + GH E V ++L+ N Sbjct: 18 AYSGKLEELKE---SILADKSLAT-RTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK 73 Query: 80 EDL-----------------------KAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 +D A VN VN+ G T LH+A+ + ++ +L E Sbjct: 74 DDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL-EG 132 Query: 117 EADPFIRNKFGHDAIFEAENSGK-EEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGT 175 A+P ++ + A+ A G + + K +D E + T + + Sbjct: 133 GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGN--TPLHLACDEERVE 190 Query: 176 EIEQVTKEATEALREETEK 194 E + + + E E+ Sbjct: 191 EAKLLVSQGASIYIENKEE 209 >6MWQ-A nrPDB Length = 493 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 48/215 (22%), Positives = 87/215 (40%), Gaps = 37/215 (17%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ ARAG D ++ + L T LH+AA GH+E V +L+ Sbjct: 7 KKLLEAARAGQDDEVRILMANGADVNAL-----DRFGLTPLHLAAQRGHLEIVEVLLKCG 61 Query: 74 SRANSAE-----------------------DLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 + N+A+ A VN ++ G T LH +++G L++V+ Sbjct: 62 ADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVE 121 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKN--S 168 +L ++ AD ++KFG A + ++G E++ K + D GK + Sbjct: 122 VLL-KHGADVNAQDKFGKTAFDISIDNGNEDLAEILQK---LNLSDIAHRIVAPGKGILA 177 Query: 169 VQITKGT---EIEQVTKEATEALREETEKLNINKD 200 + G+ ++ + E TE R +L + D Sbjct: 178 ADESTGSIAKRLQSIGTENTEENRRFYRQLLLTAD 212 >5AQA-A nrPDB Length = 418 Score = 126 bits (315), Expect = 7e-30, Method: Composition-based stats. Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 29/159 (18%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ ARAG D ++ + + +T LH+AA +GH+E V +L+ Sbjct: 16 RKLLEAARAGQDDEVRILMANGADVNAA-----DNTGTTPLHLAAYSGHLEIVEVLLKHG 70 Query: 74 SRANSAE-----------------------DLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 + ++++ A VN ++ G T LH A+ G ++V+ Sbjct: 71 ADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVE 130 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 +L + AD ++KFG ++ A + G E+ + Sbjct: 131 VLL-KAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 101 bits (250), Expect = 3e-22, Method: Composition-based stats. Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 12/117 (10%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + VR ++ A VN + TG T LH A+ +G L++V++L Sbjct: 18 LLEAARAGQDDEVRILMAN----------GADVNAADNTGTTPLHLAAYSGHLEIVEVLL 67 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 ++ AD + FG+ + A G E+ L K + + D T + + Sbjct: 68 -KHGADVDASDVFGYTPLHLAAYWGHLEIVEVLL-KNGADVNAMDSDGMTPLHLAAK 122 >5AQB-A nrPDB Length = 428 Score = 125 bits (313), Expect = 1e-29, Method: Composition-based stats. Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 16/138 (11%) Query: 15 TIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVS 74 T + A G L+ ++ + T LH+AA +GH+E V +L+ Sbjct: 49 TPLHLAAWGHLEIVECLLKNGADVNAADI-----DGYTPLHLAAFSGHLEIVEVLLK--- 100 Query: 75 RANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEA 134 A VN ++ G T LH A++ G L++V++L + AD ++KFG A Sbjct: 101 -------YGADVNADDQAGFTPLHLAAIFGHLEIVEVLL-KNGADVNAQDKFGKTPRDLA 152 Query: 135 ENSGKEEVETYFLKKYDV 152 ++G E++ K + Sbjct: 153 IDNGNEDIAEVLGKAATL 170 Score = 93.8 bits (231), Expect = 5e-20, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 13/116 (11%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + R ++ A VN +++ G T LH A+ G L++V+ L Sbjct: 18 LLEAARAGQDDECRILMAN----------GADVNALDEVGWTPLHLAA-WGHLEIVECLL 66 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSV 169 + AD + G+ + A SG E+ L KY + D++ T + Sbjct: 67 -KNGADVNAADIDGYTPLHLAAFSGHLEIVEVLL-KYGADVNADDQAGFTPLHLAA 120 >5AQ7-A nrPDB Length = 418 Score = 123 bits (308), Expect = 5e-29, Method: Composition-based stats. Identities = 34/136 (25%), Positives = 57/136 (41%), Gaps = 17/136 (12%) Query: 15 TII-LDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 T + L A G L ++ + E T LH+AA GH+E V +L+ Sbjct: 49 TPLHLAAWEGHLGIVEVLLKNGADVNA-----NDERGHTPLHLAAYTGHLEIVEVLLK-- 101 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 A VN + G LH A++ G ++V++L + AD ++KFG ++ Sbjct: 102 --------NGAGVNATDVIGTAPLHLAAMWGYKEIVEVLL-KAGADVDAQDKFGKRPLWL 152 Query: 134 AENSGKEEVETYFLKK 149 A + G E+ + Sbjct: 153 AADQGHAEIAAKLVAA 168 Score = 89.2 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 45/116 (38%), Gaps = 12/116 (10%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + VR +L A VN ++TG T LH A+ G L +V++L Sbjct: 18 LLEAARAGQDDEVRILLAN----------GADVNTADETGFTPLHLAAWEGHLGIVEVLL 67 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSV 169 + AD ++ GH + A +G E+ L K + + Sbjct: 68 -KNGADVNANDERGHTPLHLAAYTGHLEIVEVLL-KNGAGVNATDVIGTAPLHLAA 121 >5CBO-A nrPDB Length = 176 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 37/135 (27%), Positives = 60/135 (44%), Gaps = 16/135 (11%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ A AG D ++ + + T LH+AA GH E V +L+ Sbjct: 5 KKLLEAAHAGQDDEVRILMANGADVNAM-----DNFGVTPLHLAAYWGHFEIVEVLLK-- 57 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 A VN + TG+T LH A+ G L +V++L +Y AD ++KFG A Sbjct: 58 --------YGADVNASDATGDTPLHLAAKWGYLGIVEVLL-KYGADVNAQDKFGKTAFDI 108 Query: 134 AENSGKEEVETYFLK 148 + ++G E++ K Sbjct: 109 SIDNGNEDLAEILCK 123 >5MIO-C nrPDB Length = 573 Score = 122 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 38/163 (23%), Positives = 70/163 (42%), Gaps = 30/163 (18%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ ARAG D ++ + S T LH+AA GH+E V +L+ Sbjct: 412 KKLLEAARAGQDDEVRVLMANGADVNA-----TDASGLTPLHLAATYGHLEIVEVLLKHG 466 Query: 74 SRANSAE-----------------------DLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 + ++++ A VN V+ G+T L A++ G L +V+ Sbjct: 467 ADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVE 526 Query: 111 LLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE 153 L ++ AD ++KFG A + ++G E++ +K ++E Sbjct: 527 ALL-KHGADVNAQDKFGKTAYDTSIDNGSEDLAEIL-QKLNLE 567 Score = 96.1 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 53/133 (39%), Gaps = 12/133 (9%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + VR ++ A VN + +G T LH A+ G L++V++L Sbjct: 414 LLEAARAGQDDEVRVLMA----------NGADVNATDASGLTPLHLAATYGHLEIVEVLL 463 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITK 173 ++ AD + G + A G E+ L K+ + + T + + + Sbjct: 464 -KHGADVSASDLMGSTPLHLAALIGHLEIVEVLL-KHGADVNAVDTWGDTPLRLAAVMGH 521 Query: 174 GTEIEQVTKEATE 186 +E + K + Sbjct: 522 LKIVEALLKHGAD 534 >6FES-A nrPDB Length = 367 Score = 117 bits (292), Expect = 4e-27, Method: Composition-based stats. Identities = 35/132 (26%), Positives = 55/132 (41%), Gaps = 17/132 (12%) Query: 15 TII-LDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 T + L A G L ++ + E T LH+AA GH+E V +L+ Sbjct: 41 TPLHLAAWEGHLGIVEVLLKNGADVNA-----NDERGHTPLHLAAYTGHLEIVEVLLK-- 93 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 A VN + G LH A++ G ++V++L + AD ++KFG Sbjct: 94 --------NGAGVNATDVIGTAPLHLAAMWGHEEIVEVLL-KNGADARAQDKFGKTPEDL 144 Query: 134 AENSGKEEVETY 145 A ++G E V Sbjct: 145 ARDNGYESVARL 156 Score = 89.2 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 12/134 (8%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 113 L AA G + VR +L A VN ++TG T LH A+ G L +V++L Sbjct: 10 LLEAARAGQDDEVRILLAN----------GADVNTADETGFTPLHLAAWEGHLGIVEVLL 59 Query: 114 DEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITK 173 + AD ++ GH + A +G E+ L K + + Sbjct: 60 -KNGADVNANDERGHTPLHLAAYTGHLEIVEVLL-KNGAGVNATDVIGTAPLHLAAMWGH 117 Query: 174 GTEIEQVTKEATEA 187 +E + K +A Sbjct: 118 EEIVEVLLKNGADA 131 >4Z68-A nrPDB Length = 155 Score = 115 bits (287), Expect = 1e-26, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 18/156 (11%) Query: 11 EDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESES-DSTALHMAAANGHIETVRYI 69 E ++ A+AGD++++K L + + ++ C++ E ST LH AA + V Y+ Sbjct: 2 EADRQLLEAAKAGDVETVK----KLCTVQSVN-CRDIEGRQSTPLHFAAGYNRVSVVEYL 56 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHD 129 L+ A V+ +K G LH A G +V +LL ++ A + + + Sbjct: 57 LQH----------GADVHAKDKGGLVPLHNACSYGHYEVAELLV-KHGAVVNVADLWKFT 105 Query: 130 AIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEG 165 + EA GK E+ L+ + +P D T Sbjct: 106 PLHEAAAKGKYEICKLLLQ-HGADPTKKNRDGNTPL 140 Score = 41.8 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 11/61 (18%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKL 111 T LH AAA G E + +L+ A + N+ GNT L +G D+ L Sbjct: 105 TPLHEAAAKGKYEICKLLLQH----------GADPTKKNRDGNTPLDL-VKDGDTDIQDL 153 Query: 112 L 112 L Sbjct: 154 L 154 >5H76-A nrPDB Length = 201 Score = 114 bits (284), Expect = 3e-26, Method: Composition-based stats. Identities = 37/148 (25%), Positives = 61/148 (41%), Gaps = 16/148 (10%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ ARAG D ++ + + +T LH+AA +GH+E V +L+ Sbjct: 8 RKLLEAARAGQDDEVRILMANGADVNAA-----DNTGTTPLHLAAYSGHLEIVEVLLKH- 61 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 A V+ + G T LH A+ G L++V++L + AD + G + Sbjct: 62 ---------GADVDASDVFGYTPLHLAAYWGHLEIVEVLL-KNGADVNAMDSDGMTPLHL 111 Query: 134 AENSGKEEVETYFLKKYDVEPEDDEEDT 161 A G E+ LK V +D T Sbjct: 112 AAKWGYLEIVEVLLKHGAVNAQDKFGKT 139 Score = 94.5 bits (233), Expect = 2e-20, Method: Composition-based stats. Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 7/114 (6%) Query: 62 HIETVRYILETVSRANSAE-----DLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 H++ R +LE E A VN + TG T LH A+ +G L++V++L ++ Sbjct: 3 HMDLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLL-KH 61 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 AD + FG+ + A G E+ L K + + D T + + Sbjct: 62 GADVDASDVFGYTPLHLAAYWGHLEIVEVLL-KNGADVNAMDSDGMTPLHLAAK 114 >3EU9-A nrPDB Length = 240 Score = 113 bits (281), Expect = 7e-26, Method: Composition-based stats. Identities = 33/130 (25%), Positives = 56/130 (43%), Gaps = 11/130 (8%) Query: 47 SESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKL 106 + + T LH AA N I+ V+Y + S+ + L +N +T LHWA+ G L Sbjct: 39 DKENVTLLHWAAINNRIDLVKYYI---SKGAIVDQLGGDLN------STPLHWATRQGHL 89 Query: 107 DVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGK 166 +V L +Y ADP + + G I A G + Y + K + + +++ T Sbjct: 90 SMVVQLM-KYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK-GQDVDMMDQNGMTPLM 147 Query: 167 NSVQITKGTE 176 + T + Sbjct: 148 WAAYRTHSVD 157 Score = 75.7 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 30/162 (18%), Positives = 59/162 (36%), Gaps = 16/162 (9%) Query: 9 DQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRY 68 D+E+ + A +D +K + + L + +ST LH A GH+ V Sbjct: 39 DKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGG----DLNSTPLHWATRQGHLSMVVQ 94 Query: 69 ILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGH 128 +++ A + ++ G + +H A+ G +V L + D + ++ G Sbjct: 95 LMK----------YGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK-GQDVDMMDQNGM 143 Query: 129 DAIFEAENSGKEEVETYFLKKYDVEPED-DEEDTQTEGKNSV 169 + A T L ++V D+ T +V Sbjct: 144 TPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAV 185 >3EHQ-A nrPDB Length = 222 Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats. Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 17/158 (10%) Query: 45 KESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNG 104 +++ES LH AA G++ +R L D + VN ++K G+TAL+WA G Sbjct: 68 EQAESIDNPLHEAAKRGNLSWLRECL----------DNRVGVNGLDKAGSTALYWACHGG 117 Query: 105 KLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK-YDVEPEDDEE---- 159 D+V++L + + +NK G A+ A G ++ L K + + E+ Sbjct: 118 HKDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAF 177 Query: 160 DTQTEGKNSVQITK--GTEIEQVTKEATEALREETEKL 195 D T + + K GT+ + A + L +E L Sbjct: 178 DMATNAACASLLKKKQGTDAVRTLSNAEDYLDDEDSDL 215 Score = 66.4 bits (160), Expect = 8e-12, Method: Composition-based stats. Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 19/144 (13%) Query: 11 EDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYI 69 E D + +A G+L L++ + ++ STAL+ A GH + V + Sbjct: 71 ESIDNPLHEAAKRGNLSWLRE-----CLDNRVGVNGLDKAGSTALYWACHGGHKDIVEML 125 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHD 129 +N+ NK G+TALH A+ G D+V+LL + A +RN Sbjct: 126 F---------TQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLAK-GARTDLRNIEKKL 175 Query: 130 AIFEAENSGKEEVETYFLKKYDVE 153 A A + KK + Sbjct: 176 AFDMAT---NAACASLLKKKQGTD 196 >5JHQ-A nrPDB Length = 482 Score = 111 bits (276), Expect = 3e-25, Method: Composition-based stats. Identities = 47/194 (24%), Positives = 78/194 (40%), Gaps = 25/194 (12%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 ++ R GD+ +K LV ++ + S+ LH AA G + V ++L+ Sbjct: 17 RELLEACRNGDVSRVK----RLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ-- 70 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 + A V+ + G LH A G +VV LL + ADP R+ + + + E Sbjct: 71 --------MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQ-GADPNARDNWNYTPLHE 121 Query: 134 AENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTK-EATEALREET 192 A GK +V L+ + +P D ++ + K + K E EA R Sbjct: 122 AAIKGKIDVCIVLLQ-HGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGN 180 Query: 193 EK--------LNIN 198 E+ LN+N Sbjct: 181 EEKLMALLTPLNVN 194 Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats. Identities = 45/198 (22%), Positives = 81/198 (40%), Gaps = 33/198 (16%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILET 72 +D ++ AR+G+ + L L++P ++ ST LH+AA + V+ +L+ Sbjct: 169 KDELLEAARSGNEEKL----MALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 224 Query: 73 VSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIF 132 A V+ +K G LH A G +V +LL ++ A + + + Sbjct: 225 ----------GADVHAKDKGGLVPLHNACSYGHYEVTELLL-KHGACVNAMDLWQFTPLH 273 Query: 133 EAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQIT-------------KGTEIEQ 179 EA + + EV + L + +P GK++V + KG + Q Sbjct: 274 EAASKNRVEVCSLLLS-HGADPTLVN----CHGKSAVDMAPTPELRERLTYEFKGHSLLQ 328 Query: 180 VTKEATEALREETEKLNI 197 +EA A ++T L I Sbjct: 329 AAREADLAKVKKTLALEI 346 Score = 77.2 bits (188), Expect = 4e-15, Method: Composition-based stats. Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 27/175 (15%) Query: 15 TIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHI---ETVRYILE 71 +++ AR DL +K ++ E+++ K+ +S TALH A A+ H + +L Sbjct: 325 SLLQAAREADLAKVK----KTLALEIIN-FKQPQSHETALHCAVASLHPKRKQVTELLLR 379 Query: 72 TVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAI 131 A VNE NK T LH A+ DV+++L ++ A + G A+ Sbjct: 380 K----------GANVNEKNKDFMTPLHVAAERAHNDVMEVL-HKHGAKMNALDTLGQTAL 428 Query: 132 FEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTE-IEQVTKEAT 185 A +G + L Y +P T + Q+ G E ++Q+ E+T Sbjct: 429 HRAALAGHLQTCRLLLS-YGSDPSIISLQGFT----AAQM--GNEAVQQILSEST 476 >6BY9-A nrPDB Length = 328 Score = 109 bits (273), Expect = 6e-25, Method: Composition-based stats. Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 17/155 (10%) Query: 8 LDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 ++ +++ + + A G +D + + TC E + T L AA N H+E V Sbjct: 97 MEHQNKRSPLHAAAEAGHVDICHMLVQA---GANIDTCSEDQR--TPLMEAAENNHLEAV 151 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKF 126 +Y+++ A V+ + G+T LH A+ G +VV+ L + D ++ Sbjct: 152 KYLIKA----------GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG 201 Query: 127 GHDA-IFEAENSGKEEVETYFLKKYDVEPEDDEED 160 G I+ E + V+ K D+ D+EE+ Sbjct: 202 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEEN 236 Score = 101 bits (251), Expect = 2e-22, Method: Composition-based stats. Identities = 43/195 (22%), Positives = 74/195 (37%), Gaps = 54/195 (27%) Query: 11 EDQDTIILDARAGD-LDSLKDIFTT--LVSPELLSTCKESESDSTALHMAAANGHIETVR 67 EDQ T +++A + L+++K + LV P K++E ST LH+AA GH E V+ Sbjct: 133 EDQRTPLMEAAENNHLEAVKYLIKAGALVDP------KDAE-GSTCLHLAAKKGHYEVVQ 185 Query: 68 YILETVSRANSAEDLKAFVNEVNKTGNTA------------------------------- 96 Y+L VN + G T Sbjct: 186 YLLSNGQ---------MDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEEN 236 Query: 97 --LHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEP 154 LHWA+ +G +D+ ++L + D N G + A + + FL + D + Sbjct: 237 ICLHWAAFSGCVDIAEILLA-AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR-DSDV 294 Query: 155 EDDEEDTQTEGKNSV 169 ++ +T + + Sbjct: 295 TLKNKEGETPLQCAS 309 Score = 82.2 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 57/152 (37%), Gaps = 14/152 (9%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 + AR G L+ + LV + E ++ + LH AA GH++ +++ Sbjct: 69 KQLYFSARQG---ELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQA- 124 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 A ++ ++ T L A+ N L+ VK L + A ++ G + Sbjct: 125 ---------GANIDTCSEDQRTPLMEAAENNHLEAVKYLI-KAGALVDPKDAEGSTCLHL 174 Query: 134 AENSGKEEVETYFLKKYDVEPEDDEEDTQTEG 165 A G EV Y L ++ ++ T Sbjct: 175 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPM 206 >3B7B-A nrPDB Length = 237 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 36/155 (23%), Positives = 67/155 (43%), Gaps = 17/155 (10%) Query: 8 LDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 ++ +++ + + A G +D + + TC E + T L AA N H+E V Sbjct: 6 MEHQNKRSPLHAAAEAGHVDICHMLVQA---GANIDTCSEDQR--TPLMEAAENNHLEAV 60 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKF 126 +Y+++ A V+ + G+T LH A+ G +VV+ L + D ++ Sbjct: 61 KYLIKA----------GALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDG 110 Query: 127 GHDA-IFEAENSGKEEVETYFLKKYDVEPEDDEED 160 G I+ E + V+ K D+ D+EE+ Sbjct: 111 GWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEEN 145 Score = 99.2 bits (245), Expect = 9e-22, Method: Composition-based stats. Identities = 43/195 (22%), Positives = 74/195 (37%), Gaps = 54/195 (27%) Query: 11 EDQDTIILDARAGD-LDSLKDIFTT--LVSPELLSTCKESESDSTALHMAAANGHIETVR 67 EDQ T +++A + L+++K + LV P K++E ST LH+AA GH E V+ Sbjct: 42 EDQRTPLMEAAENNHLEAVKYLIKAGALVDP------KDAE-GSTCLHLAAKKGHYEVVQ 94 Query: 68 YILETVSRANSAEDLKAFVNEVNKTGNTA------------------------------- 96 Y+L VN + G T Sbjct: 95 YLLSNGQ---------MDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEEN 145 Query: 97 --LHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEP 154 LHWA+ +G +D+ ++L + D N G + A + + FL + D + Sbjct: 146 ICLHWAAFSGCVDIAEILLA-AKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR-DSDV 203 Query: 155 EDDEEDTQTEGKNSV 169 ++ +T + + Sbjct: 204 TLKNKEGETPLQCAS 218 Score = 74.9 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 47/120 (39%), Gaps = 11/120 (9%) Query: 46 ESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGK 105 E ++ + LH AA GH++ +++ A ++ ++ T L A+ N Sbjct: 7 EHQNKRSPLHAAAEAGHVDICHMLVQA----------GANIDTCSEDQRTPLMEAAENNH 56 Query: 106 LDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEG 165 L+ VK L + A ++ G + A G EV Y L ++ ++ T Sbjct: 57 LEAVKYLI-KAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPM 115 >5HKP-A nrPDB Length = 351 Score = 105 bits (262), Expect = 1e-23, Method: Composition-based stats. Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 21/172 (12%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILET 72 +D ++ AR+G+ + L L++P ++ ST LH+AA + V+ +L+ Sbjct: 25 KDELLEAARSGNEEKL----MALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 80 Query: 73 VSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIF 132 A V+ +K G LH A G +V +LL ++ A + + + Sbjct: 81 ----------GADVHAKDKGGLVPLHNACSYGHYEVTELLL-KHGACVNAMDLWQFTPLH 129 Query: 133 EAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEI-EQVTKE 183 EA + + EV + L + +P GK++V + E+ E++T E Sbjct: 130 EAASKNRVEVCSLLLS-HGADPTLVN----CHGKSAVDMAPTPELRERLTYE 176 Score = 76.1 bits (185), Expect = 9e-15, Method: Composition-based stats. Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 27/175 (15%) Query: 15 TIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHI---ETVRYILE 71 +++ AR DL +K ++ E+++ K+ +S TALH A A+ H + +L Sbjct: 181 SLLQAAREADLAKVK----KTLALEIIN-FKQPQSHETALHCAVASLHPKRKQVAELLLR 235 Query: 72 TVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAI 131 A VNE NK T LH A+ DV+++L ++ A + G A+ Sbjct: 236 K----------GANVNEKNKDFMTPLHVAAERAHNDVMEVL-HKHGAKMNALDSLGQTAL 284 Query: 132 FEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTE-IEQVTKEAT 185 A +G + L Y +P T + Q+ G E ++Q+ E+T Sbjct: 285 HRAALAGHLQTCRLLLS-YGSDPSIISLQGFT----AAQM--GNEAVQQILSEST 332 Score = 27.5 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 20/56 (35%), Gaps = 4/56 (7%) Query: 118 ADPFIR----NKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSV 169 ADP + ++ D + EA SG EE L +V + T + Sbjct: 11 ADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAA 66 >5U0K-A nrPDB Length = 141 Score = 90.3 bits (222), Expect = 5e-19, Method: Composition-based stats. Identities = 32/100 (32%), Positives = 51/100 (51%), Gaps = 16/100 (16%) Query: 16 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS-TALHMAAANGHIETVRYILETVS 74 ++ A +GD+ +L+ + + E + + DS TALH+AAA GHIE V++++E Sbjct: 29 LLFAAYSGDVSALRRFALSAMDME------QKDYDSRTALHVAAAEGHIEVVKFLIEACK 82 Query: 75 RANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCD 114 A+ ++ GN L A L+VVKLL D Sbjct: 83 VNPFAK---------DRWGNIPLDDAVQFNHLEVVKLLQD 113 Score = 43.7 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 24/76 (31%), Gaps = 13/76 (17%) Query: 108 VVKLLCDEYEADPFI-------------RNKFGHDAIFEAENSGKEEVETYFLKKYDVEP 154 VV LL Y D ++ A+ A G EV + ++ V P Sbjct: 26 VVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNP 85 Query: 155 EDDEEDTQTEGKNSVQ 170 + ++VQ Sbjct: 86 FAKDRWGNIPLDDAVQ 101 >1WG0-A nrPDB Length = 243 Score = 86.5 bits (212), Expect = 7e-18, Method: Composition-based stats. Identities = 45/225 (20%), Positives = 83/225 (36%), Gaps = 49/225 (21%) Query: 3 LHSEP--LDQEDQD--TIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAA 58 LHS+P L Q+DQD + + + + + + L + +S T H+A Sbjct: 22 LHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYPD-DSGWTPFHIAC 80 Query: 59 ANGHIETVRYIL-------------------------ETVSRANSAEDLKAFVNEVNKTG 93 + G++E V+ + + + + A V +K Sbjct: 81 SVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFN 140 Query: 94 NTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE 153 LH A+ G L +++LLC ++ ++K G +F A G + ++KY E Sbjct: 141 QIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAE 200 Query: 154 PEDDEEDTQTEGKNSVQITKGTEIEQVTKEATEALREETEKLNIN 198 + + KG + E V AL E+ +K +N Sbjct: 201 YDLVD-------------NKGAKAEDV------ALNEQVKKFFLN 226 Score = 72.2 bits (175), Expect = 2e-13, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 46/141 (32%), Gaps = 9/141 (6%) Query: 32 FTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNK 91 L+ + ++ + LH + + E ++L + N + + Sbjct: 18 VQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYP-------DD 70 Query: 92 TGNTALHWASLNGKLDVVKLLCDEY-EADPFIRNKFGHDAIFEAENSGKEEVETYFLKKY 150 +G T H A G L+VVK L D + D G + A EV + + + Sbjct: 71 SGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLI-EN 129 Query: 151 DVEPEDDEEDTQTEGKNSVQI 171 ++ Q + + Sbjct: 130 GASVRIKDKFNQIPLHRAASV 150 Score = 35.6 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 19/108 (17%), Positives = 42/108 (38%), Gaps = 10/108 (9%) Query: 94 NTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKY-DV 152 N LH A + + V+ L + +++ G + + + E+ ++ L K +V Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENV 62 Query: 153 EPEDDEED-TQTEGKNSVQITKGTEIEQVTKEATEALREETEKLNINK 199 +D +D T + + E ++L + K ++NK Sbjct: 63 NLDDYPDDSGWTPFHIACSVG--------NLEVVKSLYDRPLKPDLNK 102 >5UQE-A nrPDB Length = 520 Score = 83.4 bits (204), Expect = 6e-17, Method: Composition-based stats. Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 19/108 (17%) Query: 12 DQD-----TIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 DQ ++ A GD+ +L+ + + E + TALH+AAA GH+E V Sbjct: 412 DQRVKSVINLLFAAYTGDVSALRRFALSAMDME-----QRDYDSRTALHVAAAEGHVEVV 466 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCD 114 +++LE + ++ NT + A G DV K+L + Sbjct: 467 KFLLEACKVNPFPK---------DRWNNTPMDEALHFGHHDVFKILQE 505 Score = 39.8 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 23/78 (29%), Gaps = 13/78 (16%) Query: 106 LDVVKLLCDEYEADPFI-------------RNKFGHDAIFEAENSGKEEVETYFLKKYDV 152 V+ LL Y D R+ A+ A G EV + L+ V Sbjct: 416 KSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKV 475 Query: 153 EPEDDEEDTQTEGKNSVQ 170 P + T ++ Sbjct: 476 NPFPKDRWNNTPMDEALH 493 >4OAU-C nrPDB Length = 699 Score = 83.0 bits (203), Expect = 9e-17, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 18/166 (10%) Query: 15 TIILDARA-GDLDSLKDIFTTLVSPELLSTCKESE-----SDSTALHMAAANGHIETVRY 68 T ++A G + +LK ++ + L KE + +TAL AA GH+E ++ Sbjct: 107 TAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKI 166 Query: 69 ILETVSRANSAEDLKAFVNEVNKTGNTALHWA---SLNGKLDVVKLLCDEYEADPFIRNK 125 +L +++ A VN + G AL A S + ++ + L ++ AD +R + Sbjct: 167 LL---------DEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGE 217 Query: 126 FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQI 171 G + A + L++ +E D + D +T +V++ Sbjct: 218 RGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVEL 263 Score = 80.3 bits (196), Expect = 6e-16, Method: Composition-based stats. Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 9/167 (5%) Query: 8 LDQEDQDTI-ILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 L +++ T IL A AG + LK + ++ C TA AA G ++ + Sbjct: 67 LRKKNGATPFILAAIAGSVKLLKLFLSKGAD---VNEC--DFYGFTAFMEAAVYGKVKAL 121 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKF 126 +++ + + N K + K G TAL A+ G ++V+K+L DE AD + Sbjct: 122 KFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNM 181 Query: 127 GHDAI---FEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 G +A+ + + E T+ L + + E +T +V+ Sbjct: 182 GRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVE 228 Score = 69.1 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 38/204 (18%), Positives = 70/204 (34%), Gaps = 38/204 (18%) Query: 11 EDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYIL 70 ED +I + D+D + L+ +E E T LH A + V +L Sbjct: 4 EDNHLLIKAVQNEDVD----LVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLL 59 Query: 71 ETVSRANSAEDL-----------------------KAFVNEVNKTGNTALHWASLNGKLD 107 + + A VNE + G TA A++ GK+ Sbjct: 60 RHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVK 119 Query: 108 VVKLLCDEYEADPFIR----------NKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDD 157 +K L + A+ +R K G A+ +A G EV L + + Sbjct: 120 ALKFLY-KRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNAC 178 Query: 158 EEDTQTEGKNSVQITKGTEIEQVT 181 + + +++ + +++E +T Sbjct: 179 DNMGRNALIHALLSSDDSDVEAIT 202 Score = 47.9 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 29/160 (18%), Positives = 48/160 (30%), Gaps = 15/160 (9%) Query: 1 MGLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN 60 MG D ++ +I + D + + T L+ E T L +A Sbjct: 171 MGADVNACDNMGRNALIHALLSSDDSDV-EAITHLLLDHGADVNVRGERGKTPLILAVEK 229 Query: 61 GHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADP 120 H+ V+ +LE +N+ + G TAL A + +LLC Sbjct: 230 KHLGLVQRLLE---------QEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRG---- 276 Query: 121 FIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEED 160 G + N V+ + ED Sbjct: 277 -ASTDCGDLVMTARRNYDHSLVKVLLSHGAKEDFHPPAED 315 Score = 31.0 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 2/62 (3%) Query: 131 IFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTKE-ATEALR 189 I +N + V+ +V ++ EE T N+VQ+++ +E + + A LR Sbjct: 10 IKAVQNEDVDLVQQLLEGGANVNFQE-EEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68 Query: 190 EE 191 ++ Sbjct: 69 KK 70 >5U0J-A nrPDB Length = 140 Score = 81.8 bits (200), Expect = 2e-16, Method: Composition-based stats. Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 14/99 (14%) Query: 16 IILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSR 75 ++ A GD+ +L+ + + E + TALH+AAA GH+E V+++LE Sbjct: 28 LLFAAYTGDVSALRRFALSAMDME-----QRDYDSRTALHVAAAEGHVEVVKFLLEACKV 82 Query: 76 ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCD 114 + ++ NT + A G DV K+L + Sbjct: 83 NPFPK---------DRWNNTPMDEALHFGHHDVFKILQE 112 Score = 39.5 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 23/78 (29%), Gaps = 13/78 (16%) Query: 106 LDVVKLLCDEYEADPFI-------------RNKFGHDAIFEAENSGKEEVETYFLKKYDV 152 V+ LL Y D R+ A+ A G EV + L+ V Sbjct: 23 KSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKV 82 Query: 153 EPEDDEEDTQTEGKNSVQ 170 P + T ++ Sbjct: 83 NPFPKDRWNNTPMDEALH 100 >5D68-A nrPDB Length = 486 Score = 81.5 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 61/150 (40%), Gaps = 11/150 (7%) Query: 50 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 109 D LH +A G E + +L + VN+++ +H+A GK++ Sbjct: 38 DDFPLHRSACEGDSELLSRLLSE----------RFSVNQLDSDHWAPIHYACWYGKVEAT 87 Query: 110 KLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSV 169 ++L ++ + +P + N + A G E+ L + + ++ ++ N Sbjct: 88 RILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL-NIC 146 Query: 170 QITKGTEIEQVTKEATEALREETEKLNINK 199 + K E+ K EA+ + EK+ I + Sbjct: 147 EENKQNNWEEAAKLLKEAINKPYEKVRIYR 176 Score = 66.0 bits (159), Expect = 9e-12, Method: Composition-based stats. Identities = 42/197 (21%), Positives = 71/197 (36%), Gaps = 40/197 (20%) Query: 9 DQEDQ---DTIIL-DARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIE 64 D+E Q D + A GD + L + + E S + +H A G +E Sbjct: 31 DKERQWVDDFPLHRSACEGDSELLSRLLS-----ERFSVNQLDSDHWAPIHYACWYGKVE 85 Query: 65 TVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 R +LE N +N ++ LH+A+ G ++V++L + E D I + Sbjct: 86 ATRILLEKGKCNP---------NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITD 136 Query: 125 KFGHDAIF------------------EAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGK 166 + G + EA N E+V Y + E + T Sbjct: 137 QQGRSPLNICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTT--- 193 Query: 167 NSVQITKGTEIEQVTKE 183 QI +G + Q T++ Sbjct: 194 -VQQIMEGMRLSQETQQ 209 >1BLX-B nrPDB Length = 166 Score = 78.0 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 58/153 (37%), Gaps = 20/153 (13%) Query: 19 DARAGDLDSLKDIFTT-LVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRAN 77 A GD+ ++ + LV P+ L+ TAL + G +L+ Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALN-----RFGKTALQV-MMFGSPAVALELLKQ----- 63 Query: 78 SAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENS 137 A N + +G + +H A+ G LD +K+L E+ AD + G I A Sbjct: 64 -----GASPNVQDASGTSPVHDAARTGFLDTLKVLV-EHGADVNALDSTGSLPIHLAIRE 117 Query: 138 GKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 G V ++ + D+ + T + + Q Sbjct: 118 GHSSVVSFLAPESDL--HHRDASGLTPLELARQ 148 >1BD8-A nrPDB Length = 156 Score = 77.6 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 33/153 (21%), Positives = 60/153 (39%), Gaps = 20/153 (13%) Query: 19 DARAGDLDSLKDIFTT-LVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRAN 77 A GD+ ++ + LV P+ L+ TAL + G +L+ Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALN-----RFGKTALQVM-MFGSTAIALELLKQ----- 57 Query: 78 SAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENS 137 A N + +G + +H A+ G LD +K+L E+ AD + + G I A Sbjct: 58 -----GASPNVQDTSGTSPVHDAARTGFLDTLKVLV-EHGADVNVPDGTGALPIHLAVQE 111 Query: 138 GKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 G V ++ + D+ + T + ++Q Sbjct: 112 GHTAVVSFLAAESDL--HRRDARGLTPLELALQ 142 >4O1O-A nrPDB Length = 717 Score = 74.1 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 9/181 (4%) Query: 17 ILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRA 76 I+ G++ L+ + + E ++ C + TA AA G +E +R++ E + Sbjct: 80 IIAGITGNVRLLQLLLPNV---EDVNECDVN--GFTAFMEAAVYGRVEALRFLYENGADV 134 Query: 77 NSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAE- 135 N K + K G TAL A+ G + VV +L +A+ R+ G +A+ A Sbjct: 135 NMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALL 194 Query: 136 --NSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTKEATEALREETE 193 + GK + T L + + E ++T +V+ K ++ Q+ E + +T+ Sbjct: 195 NPDDGKAKAITRLLLDHGADVNVRGEGSKTPLILAVE-RKNLDLVQMLLEQEQIEVNDTD 253 Query: 194 K 194 + Sbjct: 254 R 254 Score = 71.8 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 75/177 (42%), Gaps = 22/177 (12%) Query: 15 TIILDARA-GDLDSLKDIFTTLVSPELLSTCKESE-----SDSTALHMAAANGHIETVRY 68 T ++A G +++L+ ++ + K+ + +TAL AA GH+ V Sbjct: 110 TAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTI 169 Query: 69 ILETVSRANSAEDLKAFVNEVNKTGNTALHWASLN---GKLDVVKLLCDEYEADPFIRNK 125 +L +KA V+ + G AL +A LN GK + L ++ AD +R + Sbjct: 170 LLHA---------MKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGADVNVRGE 220 Query: 126 FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTK 182 + A ++ L++ +E D + + +T +V++ +E++ K Sbjct: 221 GSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVEL----RLEEIAK 273 Score = 59.5 bits (142), Expect = 8e-10, Method: Composition-based stats. Identities = 30/186 (16%), Positives = 63/186 (33%), Gaps = 38/186 (20%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILET 72 ++ + + D++ ++ + + +E E + LH A + V +L+ Sbjct: 9 EEMLTQAVQEADIEQVRQLLERGAD----ANFQEEEWGWSPLHSAVQMDSEDLVALLLKH 64 Query: 73 VSRANSAEDLKA-----------------------FVNEVNKTGNTALHWASLNGKLDVV 109 + + A VNE + G TA A++ G+++ + Sbjct: 65 GADPCLRKRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEAL 124 Query: 110 KLLCDEYEADPFI-----RN-----KFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEE 159 + L E AD + ++ K G A+ +A G V T L E + + Sbjct: 125 RFLY-ENGADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDN 183 Query: 160 DTQTEG 165 + Sbjct: 184 MGRNAL 189 Score = 46.8 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 46/130 (35%), Gaps = 16/130 (12%) Query: 32 FTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNK 91 T L+ E T L +A +++ V+ +LE + VN+ ++ Sbjct: 204 ITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLE---------QEQIEVNDTDR 254 Query: 92 TGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYF-LKKY 150 G TAL A ++ KLLC A + + A + ++ + L K Sbjct: 255 EGKTALLLAVELRLEEIAKLLC-HRGASTNCGD-----LVAIARRNYDSDLVKFLRLHKA 308 Query: 151 DVEPEDDEED 160 + E+ Sbjct: 309 GEDFRPPAEN 318 >6AUN-A nrPDB Length = 752 Score = 71.1 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 26/108 (24%), Positives = 42/108 (38%), Gaps = 9/108 (8%) Query: 40 LLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHW 99 + E+E T LH+A G E + +++ A ++ + G TA H+ Sbjct: 142 SCANSTENEEGCTPLHLACRKGDSEILVELVQYCH---------AQMDVTDNKGETAFHY 192 Query: 100 ASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFL 147 A V++LL A NK G + A GK+E+ L Sbjct: 193 AVQGDNSQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGKQEMVRVLL 240 Score = 68.4 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 28/169 (16%), Positives = 50/169 (29%), Gaps = 13/169 (7%) Query: 8 LDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS---TALHMAAANGHIE 64 L+ E + + L + ++ E+L + T H+A G Sbjct: 74 LESEADALVNFQQFSSQLPPFYESSVQVLHVEVLQHLSDLIRSHPSWTVTHLAVELG--- 130 Query: 65 TVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 +R + A + N+ G T LH A G +++ L A + + Sbjct: 131 -IRECFHHSRIISCAN------STENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTD 183 Query: 125 KFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITK 173 G A A +V K + T + Q+ K Sbjct: 184 NKGETAFHYAVQGDNSQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGK 232 Score = 65.7 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 52/129 (40%), Gaps = 15/129 (11%) Query: 45 KESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNG 104 K+ ++ LH A + E R +L+ V+ + GNTALH A + Sbjct: 282 KDPRYGASPLHWAK---NAEMARMLLKR----------GCDVDSTSAAGNTALHVAVMRN 328 Query: 105 KLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTE 164 + D V +L Y A+ + G+ + A + E+ + + E + + +T Sbjct: 329 RFDCVMVLLT-YGANAGTPGEHGNTPLHLAISKDNMEMIKALIV-FGAEVDTPNDFGETP 386 Query: 165 GKNSVQITK 173 + +I+K Sbjct: 387 AFMASKISK 395 Score = 58.3 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 26/154 (16%), Positives = 49/154 (31%), Gaps = 29/154 (18%) Query: 40 LLSTCKESESDSTALHMAAANGHIETVRYILETVSRAN---------------------- 77 + ++ T LH+A G E VR +L +R N Sbjct: 210 SAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAE 269 Query: 78 --SAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAE 135 + D ++ + G + LHWA ++ ++L + D + G+ A+ A Sbjct: 270 MIISMDSSQIHSKDPRYGASPLHWA---KNAEMARMLL-KRGCDVDSTSAAGNTALHVAV 325 Query: 136 NSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSV 169 + + L Y E T ++ Sbjct: 326 MRNRFDCVMVLLT-YGANAGTPGEHGNTPLHLAI 358 Score = 55.6 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 41/114 (35%), Gaps = 16/114 (14%) Query: 21 RAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAE 80 A + + + + + S + +TALH+A + V +L Sbjct: 293 WAKNAEMARMLLKRGCDVDS-----TSAAGNTALHVAVMRNRFDCVMVLLT--------- 338 Query: 81 DLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEA 134 A + GNT LH A ++++K L + A+ N FG F A Sbjct: 339 -YGANAGTPGEHGNTPLHLAISKDNMEMIKALIV-FGAEVDTPNDFGETPAFMA 390 Score = 44.5 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 16/101 (15%), Positives = 33/101 (32%), Gaps = 9/101 (8%) Query: 94 NTALHWASLNGKLDVVKLLCDEYEADPFI----RNKFGHDAIFEAENSGKEEVETYFLKK 149 T H A G + C + N+ G + A G E+ ++ Sbjct: 120 WTVTHLAVELGIRE-----CFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQY 174 Query: 150 YDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTKEATEALRE 190 + + + +T +VQ ++ + K A+ L + Sbjct: 175 CHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQ 215 >1G3N-B nrPDB Length = 168 Score = 70.7 bits (171), Expect = 4e-13, Method: Composition-based stats. Identities = 32/133 (24%), Positives = 56/133 (42%), Gaps = 15/133 (11%) Query: 14 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 73 T + + G+ + + + +P+L + + +H AA G ++T++ +LE Sbjct: 39 RTALQVMKLGNPEIARRLLLRGANPDL-----KDRTGFAVIHDAARAGFLDTLQTLLE-- 91 Query: 74 SRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFE 133 +A VN + GN LH A+ G L VV+ L ++ RN G A Sbjct: 92 --------FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDL 143 Query: 134 AENSGKEEVETYF 146 A G+ EV + Sbjct: 144 ARLYGRNEVVSLM 156 Score = 66.4 bits (160), Expect = 7e-12, Method: Composition-based stats. Identities = 35/159 (22%), Positives = 58/159 (36%), Gaps = 21/159 (13%) Query: 5 SEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIE 64 +EP E + A GDL+ L + V+ + TAL + G+ E Sbjct: 2 AEPWGNE----LASAAARGDLEQLTSLLQNNVNVNAQNGF-----GRTALQVM-KLGNPE 51 Query: 65 TVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 R +L A + ++TG +H A+ G LD ++ L E++AD I + Sbjct: 52 IARRLLLR----------GANPDLKDRTGFAVIHDAARAGFLDTLQTLL-EFQADVNIED 100 Query: 125 KFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQT 163 G+ + A G V + +K T Sbjct: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDT 139 Score = 52.9 bits (125), Expect = 8e-08, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 44/106 (41%), Gaps = 15/106 (14%) Query: 19 DARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANS 78 ARAG LD+L+ + + E + LH+AA GH+ V ++++ + Sbjct: 77 AARAGFLDTLQTLLEFQADVNI-----EDNEGNLPLHLAAKEGHLRVVEFLVKHTASN-- 129 Query: 79 AEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY-EADPFIR 123 V N G+TA A L G+ +VV L+ ++ Sbjct: 130 -------VGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 >4OT9-A nrPDB Length = 359 Score = 69.5 bits (168), Expect = 8e-13, Method: Composition-based stats. Identities = 42/221 (19%), Positives = 70/221 (31%), Gaps = 45/221 (20%) Query: 3 LHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMA--AAN 60 LH PL L G + + P LL +A+H+A A Sbjct: 120 LHQTPLH--------LAVITGQTSVVSFLLRVGADPALL-----DRHGDSAMHLALRAGA 166 Query: 61 GHIETVRYILETVSRA----------------------------NSAEDLKAFVNEVN-K 91 G E +R +L++ + A + D A V + Sbjct: 167 GAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQ 226 Query: 92 TGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYD 151 G TALH A+ +L +V L + A+ R G+ + A G + L K Sbjct: 227 GGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLL-KAG 285 Query: 152 VEPEDDEEDTQTEGKNSVQITKGTEIEQVTKEATEALREET 192 + + E+ + ++ E K+ + R T Sbjct: 286 ADIHAENEEPLCPLPSPPTSDSDSDSEGPEKDTRSSFRGHT 326 Score = 68.0 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 39/185 (21%), Positives = 69/185 (37%), Gaps = 24/185 (12%) Query: 32 FTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNK 91 L++ + + E+ T LH+A +G + I+ + + A+DL VN N Sbjct: 64 ARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVI---HHAQDLGV-VNLTNH 119 Query: 92 TGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGK---EEVETYFLK 148 T LH A + G+ VV L ADP + ++ G A+ A +G E + Sbjct: 120 LHQTPLHLAVITGQTSVVSFLL-RVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQS 178 Query: 149 KYDVEP---EDDEEDTQTEGKNSVQ----------ITKGTEIEQVTKEATEA---LREET 192 P + + +V+ + G E+E ++ L E Sbjct: 179 GAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEM 238 Query: 193 EKLNI 197 E+L + Sbjct: 239 EELGL 243 >3T9K-A nrPDB Length = 390 Score = 65.7 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 53/142 (37%), Gaps = 12/142 (8%) Query: 5 SEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIE 64 SE L ++ A +G SL + L ++ + ++T L A A + Sbjct: 191 SEDLGSLHPGALLFRA-SGHPPSLPTMADALAHGADVNWVNGGQDNATPLIQATAANSLL 249 Query: 65 TVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 ++L+ A VN+ + G LH A++ G + L + AD R+ Sbjct: 250 ACEFLLQ----------NGANVNQADSAGRGPLHHATILGHTGLA-CLFLKRGADLGARD 298 Query: 125 KFGHDAIFEAENSGKEEVETYF 146 G D + A + ++ T Sbjct: 299 SEGRDPLTIAMETANADIVTLL 320 Score = 48.3 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 34/96 (35%), Gaps = 4/96 (4%) Query: 77 NSAEDLKAFVNEVN--KTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEA 134 A A VN VN + T L A+ L + L + A+ + G + A Sbjct: 217 ADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLL-QNGANVNQADSAGRGPLHHA 275 Query: 135 ENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQ 170 G + FLK+ + + + + +++ Sbjct: 276 TILGHTGLACLFLKR-GADLGARDSEGRDPLTIAME 310 >3ZKJ-A nrPDB Length = 261 Score = 65.3 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 30/123 (24%), Positives = 49/123 (39%), Gaps = 15/123 (12%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDV 108 SD + +H AA +GH ++R ++ VN + + LH A L G L Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQ----------GWAVNIITADHVSPLHEACLGGHLSC 51 Query: 109 VKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK-KYDVEPEDDEEDTQTEGKN 167 VK+L ++ A H +F A SG + L+ V+P E D + Sbjct: 52 VKILL-KHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP---ESDLASPIHE 107 Query: 168 SVQ 170 + + Sbjct: 108 AAR 110 Score = 63.0 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 25/154 (16%), Positives = 53/154 (34%), Gaps = 20/154 (12%) Query: 12 DQDTIILDA-RAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYIL 70 D T + +A +G D + + + ++ + ++ +H AA GH+E V ++ Sbjct: 68 DWHTPLFNACVSGSWDCVNLLL------QHGASVQPESDLASPIHEAARRGHVECVNSLI 121 Query: 71 ETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDA 130 + T L+ A N + VK L E AD + K Sbjct: 122 AYGGNIDHKISHLG----------TPLYLACENQQRACVKKLL-ESGADVN-QGKGQDSP 169 Query: 131 IFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTE 164 + + EE+ + + + + + + Sbjct: 170 LHAVARTASEELACLLM-DFGADTQAKNAEGKRP 202 Score = 57.6 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 21/144 (14%), Positives = 44/144 (30%), Gaps = 31/144 (21%) Query: 52 TALHMAAANGHIETVRYILETVSRANSAE-----------------------DLKAFVNE 88 + LH A GH+ V+ +L+ ++ N A V Sbjct: 38 SPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP 97 Query: 89 VNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENS-GKEEVETYFL 147 + + +H A+ G ++ V L Y + + ++ A + + V+ Sbjct: 98 ESDLAS-PIHEAARRGHVECVNSLIA-YGGNIDHKISHLGTPLYLACENQQRACVKKLLE 155 Query: 148 KKYDVEPEDDEEDTQ-TEGKNSVQ 170 DV + Q + + Sbjct: 156 SGADVN----QGKGQDSPLHAVAR 175 >2KXP-C nrPDB Length = 118 Score = 65.3 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 12/113 (10%) Query: 56 MAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDE 115 A NG ++ V+ + VN + G LH+A+ G+L++++ L + Sbjct: 8 WALKNGDLDEVKDYVAK----------GEDVNRTLEGGRKPLHYAADCGQLEILEFLLLK 57 Query: 116 YEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNS 168 AD +K + A G L K + D T + + Sbjct: 58 -GADINAPDKHHITPLLSAVYEGHVSCVKLLLSK-GADKTVKGPDGLTALEAT 108 Score = 63.0 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 16/121 (13%) Query: 17 ILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRA 76 + + GDLD +KD + + E LH AA G +E + ++L Sbjct: 7 MWALKNGDLDEVKDYVA-----KGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLK---- 57 Query: 77 NSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAEN 136 A +N +K T L A G + VKLL + AD ++ G A+ +N Sbjct: 58 ------GADINAPDKHHITPLLSAVYEGHVSCVKLLLSK-GADKTVKGPDGLTALEATDN 110 Query: 137 S 137 Sbjct: 111 Q 111 >6EMK-G nrPDB Length = 426 Score = 63.0 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 51/145 (35%), Gaps = 12/145 (8%) Query: 22 AGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAED 81 G+L +K + L T +SE+ ++LH A+ +G Y+++ + Sbjct: 15 EGNLLIVKRLLRRNPD---LLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIK 71 Query: 82 LKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEE 141 GNT +H A + G + LL ++ R + G I A + + Sbjct: 72 --------TFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQ 123 Query: 142 VETYFLKKYDVEPEDDEEDTQTEGK 166 + + + + + T Sbjct: 124 CLSLLI-GVGADLWVMDTNGDTPLH 147 Score = 57.6 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 50/137 (36%), Gaps = 12/137 (8%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDV 108 +T +H+A GH +T+ +L+ R F+N + G +H A +N Sbjct: 74 KGNTCVHLALMKGHEQTLHLLLQQFPR---------FINHRGENGRAPIHIACMNDYYQC 124 Query: 109 VKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEED--TQTEGK 166 + LL AD ++ + G + G L + +V +D+ D Sbjct: 125 LSLLIG-VGADLWVMDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKPID 183 Query: 167 NSVQITKGTEIEQVTKE 183 + G +V KE Sbjct: 184 VAQTFEVGNIYSKVLKE 200 Score = 53.3 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 44/104 (42%), Gaps = 12/104 (11%) Query: 48 ESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD 107 E+ +H+A N + + + ++ + A + ++ G+T LH G + Sbjct: 107 ENGRAPIHIACMNDYYQCLSLLI----------GVGADLWVMDTNGDTPLHVCLEYGSIS 156 Query: 108 VVKLLCDEYEA--DPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 +K+L +E E D +R+K I A+ + + LK+ Sbjct: 157 CMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKE 200 Score = 50.6 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNG-KLDVVKLL 112 L A G++ V+ +L + N ++ G ++LH+AS +G L V L+ Sbjct: 9 LREAIIEGNLLIVKRLLRRNPDLLT--------NIDSENGWSSLHYASYHGRYLICVYLI 60 Query: 113 CDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNS 168 ++ I+ G+ + A G E+ L+++ E+ + + Sbjct: 61 QLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIA 116 Score = 29.1 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 9/57 (15%), Positives = 18/57 (31%), Gaps = 7/57 (12%) Query: 47 SESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLN 103 + T LH+ G I ++ +L ++ N +K + A Sbjct: 139 DTNGDTPLHVCLEYGSISCMKMLLNEG-------EVSLDDNVRDKGNWKPIDVAQTF 188 >5DND-A nrPDB Length = 588 Score = 58.0 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 44/106 (41%), Gaps = 18/106 (16%) Query: 20 ARAGDLDSLKDIFTTLVSPELLSTCKESES-DSTALHMAAANGHIETVRYILETVSRANS 78 A AG+L++L+ + EL S + +S T LH+AA NG V +L Sbjct: 430 AHAGELEALQAL------MELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLL-------- 475 Query: 79 AEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 VN ++ G + L A + ++LL + A ++ Sbjct: 476 --HRGMDVNARDRDGLSPLLLAVQGRHRECIRLL-RKAGACLSPQD 518 Score = 56.4 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 51/128 (39%), Gaps = 17/128 (13%) Query: 40 LLSTCKESESDSTA----LHMA-AANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGN 94 L C+E +S A L +A A G +E ++ ++E L + + + G Sbjct: 407 SLFGCQEEDSVQDAVMPSLALALAHAGELEALQALME----------LGSDLRLKDSNGQ 456 Query: 95 TALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK-KYDVE 153 T LH A+ NG+ VV +L D R++ G + A E K + Sbjct: 457 TLLHVAARNGRDGVVTMLL-HRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGACLS 515 Query: 154 PEDDEEDT 161 P+D ++ Sbjct: 516 PQDLKDAG 523 >2RFA-A nrPDB Length = 232 Score = 56.0 bits (133), Expect = 9e-09, Method: Composition-based stats. Identities = 30/170 (17%), Positives = 59/170 (34%), Gaps = 30/170 (17%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS---TALHMAAANGHIETVRYI 69 + ++L A+ D+ +L + C+ + + TALH+AA ++E + Sbjct: 4 ESPLLLAAKENDVQALSKLLK-------FEGCEVHQRGAMGETALHIAALYDNLEAAMVL 56 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNK---- 125 +E + G TALH A +N +++V+ L A R Sbjct: 57 MEAAPELVFEP-----MTSELYEGQTALHIAVINQNVNLVRALLAR-GASVSARATGSVF 110 Query: 126 ---------FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGK 166 +G + A G EE+ + ++ + + T Sbjct: 111 HYRPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLH 159 Score = 53.3 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 8/121 (6%) Query: 18 LDARAGDLDSLKDIFTTLVSPELLSTCKESE--SDSTALHMAAANGHIETVRYILETVSR 75 + A +L++ + +PEL+ SE TALH+A N ++ VR +L + Sbjct: 43 IAALYDNLEAAMVLMEA--APELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 100 Query: 76 ANSAEDLKAF---VNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIF 132 ++ F + + G L +A+ G ++V+LL E+ AD ++ G+ + Sbjct: 101 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLH 159 Query: 133 E 133 Sbjct: 160 I 160 Score = 36.0 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 24/79 (30%), Gaps = 4/79 (5%) Query: 95 TALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYD--- 151 + L A+ + + L + R G A+ A E ++ Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64 Query: 152 VEPEDDE-EDTQTEGKNSV 169 EP E + QT +V Sbjct: 65 FEPMTSELYEGQTALHIAV 83 >2A5E-A nrPDB Length = 156 Score = 56.0 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 42/121 (34%), Gaps = 24/121 (19%) Query: 54 LHMAAANGHIETVRYILETVSRANSAEDL----------------------KAFVNEVNK 91 L AAA G +E VR +LE + N+ A N + Sbjct: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADP 75 Query: 92 TGNT-ALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKY 150 T +H A+ G LD + +L A +R+ +G + AE G +V Y Sbjct: 76 ATLTRPVHDAAREGFLDTLVVL-HRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 Query: 151 D 151 Sbjct: 135 G 135 Score = 37.9 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 26/74 (35%), Gaps = 10/74 (13%) Query: 44 CKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLN 103 C + + + +H AA G ++T+ + A ++ + G + A Sbjct: 72 CADPATLTRPVHDAAREGFLDTLVVL----------HRAGARLDVRDAWGRLPVDLAEEL 121 Query: 104 GKLDVVKLLCDEYE 117 G DV + L Sbjct: 122 GHRDVARYLRAAAG 135 >1D9S-A nrPDB Length = 136 Score = 55.3 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 43/126 (34%), Gaps = 24/126 (19%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAEDL----------------------KAFV 86 S L AAA G +ETVR +LE + N+ A Sbjct: 11 SSDAGLATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEP 70 Query: 87 NEVNKTGNT-ALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETY 145 N + T +H A+ G LD + +L A + + +G + AE G ++ Y Sbjct: 71 NCADPATLTRPVHDAAREGFLDTLVVL-HRAGARLDVCDAWGRLPVDLAEEQGHRDIARY 129 Query: 146 FLKKYD 151 Sbjct: 130 LHAATG 135 Score = 39.1 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 16/122 (13%), Positives = 37/122 (30%), Gaps = 38/122 (31%) Query: 19 DARAGDLDSLKDIFTTLVSPELLS----------------------------TCKESESD 50 A G +++++ + P L+ C + + Sbjct: 19 AAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCADPATL 78 Query: 51 STALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVK 110 + +H AA G ++T+ + A ++ + G + A G D+ + Sbjct: 79 TRPVHDAAREGFLDTLVVL----------HRAGARLDVCDAWGRLPVDLAEEQGHRDIAR 128 Query: 111 LL 112 L Sbjct: 129 YL 130 Score = 38.7 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 4/72 (5%) Query: 100 ASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEE 159 A+ G+++ V+ L E ADP N+FG I G +V L + EP + Sbjct: 19 AAARGQVETVRQLL-EAGADPNALNRFGRRPIQVMM-MGSAQVAELLLL-HGAEPNCADP 75 Query: 160 DTQT-EGKNSVQ 170 T T ++ + Sbjct: 76 ATLTRPVHDAAR 87 >6E2G-A nrPDB Length = 727 Score = 54.5 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 29/170 (17%), Positives = 59/170 (34%), Gaps = 30/170 (17%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS---TALHMAAANGHIETVRYI 69 + ++L A+ ++ +L + C+ + + TALH+AA ++E + Sbjct: 46 ESPLLLAAKENNVQALIKLLK-------FEGCEVHQKGAMGETALHIAALYDNLEAAMVL 98 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNK---- 125 +E + G TALH A +N +++V+ L A R Sbjct: 99 MEAAPELVFEP-----MTSELYEGQTALHIAVINQNVNLVRALLAR-GASVSARATGSVF 152 Query: 126 ---------FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGK 166 +G + A G EE+ + ++ + + T Sbjct: 153 HYRPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLH 201 Score = 53.3 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 8/121 (6%) Query: 18 LDARAGDLDSLKDIFTTLVSPELLSTCKESE--SDSTALHMAAANGHIETVRYILETVSR 75 + A +L++ + +PEL+ SE TALH+A N ++ VR +L + Sbjct: 85 IAALYDNLEAAMVLMEA--APELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 142 Query: 76 ANSAEDLKAF---VNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIF 132 ++ F + + G L +A+ G ++V+LL E+ AD ++ G+ + Sbjct: 143 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLH 201 Query: 133 E 133 Sbjct: 202 I 202 Score = 34.8 bits (78), Expect = 0.027, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 24/79 (30%), Gaps = 4/79 (5%) Query: 95 TALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYD--- 151 + L A+ + + L + + G A+ A E ++ Sbjct: 47 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 152 VEPEDDE-EDTQTEGKNSV 169 EP E + QT +V Sbjct: 107 FEPMTSELYEGQTALHIAV 125 >6DMR-A nrPDB Length = 730 Score = 54.5 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 4/87 (4%) Query: 50 DSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNK---TGNTALHWASLNGKL 106 TALH+A N ++ VR +L + ++ AF + G L +A+ G Sbjct: 117 GQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSE 176 Query: 107 DVVKLLCDEYEADPFIRNKFGHDAIFE 133 ++V+LL E+ AD ++ G+ + Sbjct: 177 EIVRLLI-EHGADIRAQDSLGNTVLHI 202 Score = 51.4 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 35/175 (20%), Positives = 59/175 (33%), Gaps = 28/175 (16%) Query: 8 LDQED-QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESES--DSTALHMAAANGHIE 64 L QE +D+ +L A + D+ + S + TALH+AA ++E Sbjct: 39 LQQERIRDSPLLQAAKEN-----DLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLE 93 Query: 65 TVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 ++E L G TALH A +N L++V+ L A R Sbjct: 94 AATLLMEAAPELAKEPAL-----CEPFVGQTALHIAVMNQNLNLVRALLAR-GASVSARA 147 Query: 125 K-------------FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGK 166 +G + A G EE+ + ++ + + T Sbjct: 148 TGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLI-EHGADIRAQDSLGNTVLH 201 Score = 31.8 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 21/112 (18%), Positives = 38/112 (33%), Gaps = 12/112 (10%) Query: 67 RYILETVSRANSAEDLKAFVN--EVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 + ++ E + VN + + ++ L A+ L ++K+L D R Sbjct: 17 KLLISWPVGEQDWEQYRDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQSCDFQQRG 76 Query: 125 KFGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEED-------TQTEGKNSV 169 G A+ A E T ++ PE +E QT +V Sbjct: 77 AVGETALHVAALYDNLEAATLLMEAA---PELAKEPALCEPFVGQTALHIAV 125 >5IRX-A nrPDB Length = 636 Score = 54.1 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 59/185 (31%), Gaps = 29/185 (15%) Query: 10 QEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYI 69 Q D ++LD DSLK + TALH+A ++ V + Sbjct: 64 QNDTIALLLDVAR-KTDSLKQFVNASYTDSYY-------KGQTALHIAIERRNMTLVTLL 115 Query: 70 LETVSRANSAEDLKAFVNEVNKTGN----TALHWASLNGKLDVVKLLCDEY--EADPFIR 123 +E + +A + F + G L A+ +L +VK L AD R Sbjct: 116 VENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISAR 175 Query: 124 NKFGHDAIF---EAENSGKEEVE-------TYFLKKYDVEPEDDEED-----TQTEGKNS 168 + G+ + E ++ + + + + P E+ T + Sbjct: 176 DSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALA 235 Query: 169 VQITK 173 K Sbjct: 236 ASSGK 240 >2NYJ-A nrPDB Length = 273 Score = 54.1 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 59/185 (31%), Gaps = 29/185 (15%) Query: 10 QEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYI 69 Q D ++LD DSLK + TALH+A ++ V + Sbjct: 69 QNDTIALLLDVAR-KTDSLKQFVNASYTDSYY-------KGQTALHIAIERRNMTLVTLL 120 Query: 70 LETVSRANSAEDLKAFVNEVNKTGN----TALHWASLNGKLDVVKLLCDEY--EADPFIR 123 +E + +A + F + G L A+ +L +VK L AD R Sbjct: 121 VENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISAR 180 Query: 124 NKFGHDAIF---EAENSGKEEVE-------TYFLKKYDVEPEDDEED-----TQTEGKNS 168 + G+ + E ++ + + + + P E+ T + Sbjct: 181 DSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLKLEEITNRKGLTPLALA 240 Query: 169 VQITK 173 K Sbjct: 241 ASSGK 245 >6DVZ-A nrPDB Length = 791 Score = 53.7 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 78/211 (36%), Gaps = 28/211 (13%) Query: 3 LHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGH 62 L+ P +E ++ A D+ L + E + TAL++A Sbjct: 177 LNINPNTKEIVRILLAFAEENDI--LDRFINAEYTEE-------AYEGQTALNIAIERRQ 227 Query: 63 IETVRYILETVSRANSAEDLKAFVNEVNK-----TGNTALHWASLNGKLDVVKLLCDEYE 117 + ++ + N A F N + G T L A+ + ++V+LL + + Sbjct: 228 GDITAVLIAAGADVN-AHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQ 286 Query: 118 ADPFIRNKFGHDAIFE----AENSG------KEEVETYFLKKYDVEPE-DDEEDTQTEGK 166 D ++ G++ + AE+ K + L+ + E E D T + Sbjct: 287 TDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQ 346 Query: 167 NSVQITKGTEIEQV-TKEATEA-LREETEKL 195 + ++ K ++ + ++E E LR + K Sbjct: 347 LAAKMGKAEILKYILSREIKEKPLRSLSRKF 377 >3LVQ-E nrPDB Length = 497 Score = 53.7 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 53 ALHMA---AANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 109 LH+A A + V +I++ ++ GNTALH+A+L + D + Sbjct: 174 VLHLAVKVANQASLPLVDFIIQ----------NGGHLDAKAADGNTALHYAALYNQPDCL 223 Query: 110 KLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 KLL + A N+ G A+ A +E E + Sbjct: 224 KLLL-KGRALVGTVNEAGETALDIARKKHHKECEELLEQA 262 Score = 39.8 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 10/66 (15%) Query: 47 SESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKL 106 + +TALH AA + ++ +L+ +A V VN+ G TAL A Sbjct: 204 AADGNTALHYAALYNQPDCLKLLLKG----------RALVGTVNEAGETALDIARKKHHK 253 Query: 107 DVVKLL 112 + +LL Sbjct: 254 ECEELL 259 >2B0O-E nrPDB Length = 301 Score = 53.7 bits (127), Expect = 6e-08, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 14/100 (14%) Query: 53 ALHMA---AANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVV 109 LH+A A + V +I++ ++ GNTALH+A+L + D + Sbjct: 193 VLHLAVKVANQASLPLVDFIIQ----------NGGHLDAKAADGNTALHYAALYNQPDCL 242 Query: 110 KLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 KLL + A N+ G A+ A +E E + Sbjct: 243 KLLL-KGRALVGTVNEAGETALDIARKKHHKECEELLEQA 281 Score = 39.8 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 10/66 (15%) Query: 47 SESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKL 106 + +TALH AA + ++ +L+ +A V VN+ G TAL A Sbjct: 223 AADGNTALHYAALYNQPDCLKLLLKG----------RALVGTVNEAGETALDIARKKHHK 272 Query: 107 DVVKLL 112 + +LL Sbjct: 273 ECEELL 278 >4N5Q-A nrPDB Length = 257 Score = 51.8 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 33/201 (16%), Positives = 72/201 (35%), Gaps = 27/201 (13%) Query: 3 LHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGH 62 L+ P +E ++ A D+ L + E + TAL++A Sbjct: 61 LNINPNTKEIVRILLAFAEENDI--LDRFINAEYTEE-------AYEGQTALNIAIERRQ 111 Query: 63 IETVRYILETVSRANSAEDLKAFVNEVNK-----TGNTALHWASLNGKLDVVKLLCDEYE 117 + ++ + N A F N + G T L A+ + ++V+LL + + Sbjct: 112 GDITAVLIAAGADVN-AHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQ 170 Query: 118 ADPFIRNKFGHDAIFEAE----------NSGKEEVETYFLKKYDVEPE-DDEEDTQTEGK 166 D ++ G++ + + K + L+ + E E D T + Sbjct: 171 TDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLTPLQ 230 Query: 167 NSVQITKGTEIEQV-TKEATE 186 + ++ K ++ + ++E E Sbjct: 231 LAAKMGKAEILKYILSREIKE 251 >6BOA-A nrPDB Length = 742 Score = 51.4 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 8/121 (6%) Query: 18 LDARAGDLDSLKDIFTTLVSPELLSTCKESE--SDSTALHMAAANGHIETVRYILETVSR 75 + A +L++ + +PEL+ SE TALH+A N ++ VR +L + Sbjct: 85 IAALYDNLEAAMVLMEA--APELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 142 Query: 76 ANSAEDLKAFVNE---VNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIF 132 ++ AF + G L +A+ ++V+LL E+ AD ++ G+ + Sbjct: 143 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLI-EHGADIRAQDSLGNTVLH 201 Query: 133 E 133 Sbjct: 202 I 202 Score = 50.6 bits (119), Expect = 5e-07, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 58/170 (34%), Gaps = 30/170 (17%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDS---TALHMAAANGHIETVRYI 69 + ++L A+ D+ +L + CK + + TALH+AA ++E + Sbjct: 46 ESPLLLAAKDNDVQALNKLLK-------YEDCKVHQRGAMGETALHIAALYDNLEAAMVL 98 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNK---- 125 +E + G TALH A +N +++V+ L A R Sbjct: 99 MEAAPELVFEP-----MTSELYEGQTALHIAVVNQNMNLVRALLAR-RASVSARATGTAF 152 Query: 126 ---------FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGK 166 FG + A EE+ + ++ + + T Sbjct: 153 RRSPCNLIYFGEHPLSFAACVNSEEIVRLLI-EHGADIRAQDSLGNTVLH 201 Score = 33.7 bits (75), Expect = 0.058, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 25/79 (31%), Gaps = 4/79 (5%) Query: 95 TALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYD--- 151 + L A+ + + + L + R G A+ A E ++ Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 152 VEPEDDE-EDTQTEGKNSV 169 EP E + QT +V Sbjct: 107 FEPMTSELYEGQTALHIAV 125 >3LJN-A nrPDB Length = 364 Score = 48.3 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 45/125 (36%), Gaps = 13/125 (10%) Query: 34 TLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTG 93 ++ L+ K + + +H+AA G + VR ++ET N+ G Sbjct: 4 SMTDFPKLNRIKSDDENMEKIHVAARKGQTDEVRRLIETGVSPTI----------QNRFG 53 Query: 94 NTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDVE 153 TALH A G +D K L E G I A + K ++ ++ Sbjct: 54 CTALHLACKFGCVDTAKYLASVGEVHSLWH---GQKPIHLAVMANKTDLVVALVEGAKER 110 Query: 154 PEDDE 158 + E Sbjct: 111 GQMPE 115 Score = 47.9 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 43/117 (36%), Gaps = 10/117 (8%) Query: 89 VNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 + +H A+ G+ D V+ L E P I+N+FG A+ A G + Y Sbjct: 16 SDDENMEKIHVAARKGQTDEVRRLI-ETGVSPTIQNRFGCTALHLACKFGCVDTAKYL-- 72 Query: 149 KYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTKEAT------EALREETEKLNINK 199 V Q +V K + + + A E+L E ++ +N+ Sbjct: 73 -ASVGEVHSLWHGQKPIHLAVMANKTDLVVALVEGAKERGQMPESLLNECDEREVNE 128 Score = 42.5 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 7/123 (5%) Query: 30 DIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEV 89 ++ LV T K+ +D T L A + E + +++TV +S ++ Sbjct: 154 EMIKILVQLGASPTAKDK-ADETPLMRAMEFRNREALDLMMDTVPSKSSLR-----LDYA 207 Query: 90 NKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 149 NK GN+ LHWA L D V + E D + + ++ + + + L+K Sbjct: 208 NKQGNSHLHWAILINWED-VAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELLQK 266 Query: 150 YDV 152 DV Sbjct: 267 TDV 269 >1DCQ-A nrPDB Length = 278 Score = 47.2 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 24/107 (22%), Positives = 42/107 (39%), Gaps = 14/107 (13%) Query: 48 ESDSTALHMAAA---NGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNG 104 E D TALH+A + V ++++ +++ G+TALH+ L Sbjct: 167 EPDETALHLAVRSVDRTSLHIVDFLVQN----------SGNLDKQTGKGSTALHYCCLTD 216 Query: 105 KLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYD 151 + +KLL +A I N+ G + A+ E E + Sbjct: 217 NAECLKLLL-RGKASIEIANESGETPLDIAKRLKHEHCEELLTQALS 262 Score = 37.2 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 12/103 (11%) Query: 10 QEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYI 69 + D+ + L R+ D SL + + K++ STALH + E ++ + Sbjct: 167 EPDETALHLAVRSVDRTSLH--IVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLL 224 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 112 L KA + N++G T L A +LL Sbjct: 225 LRG----------KASIEIANESGETPLDIAKRLKHEHCEELL 257 >6CV9-A nrPDB Length = 842 Score = 46.0 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 14/91 (15%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G+I VR +LE N VN V+ G AL A N L++ +LL + Sbjct: 16 AAEYGNIPVVRKMLEECHSLN--------VNCVDYMGQNALQLAVANEHLEITELLLKKE 67 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFL 147 ++ G DA+ A + G + L Sbjct: 68 NL-----SRVG-DALLLAISKGYVRIVEAIL 92 Score = 42.2 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 99 WASLNGKLDVVKLLCDE-YEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDV 152 A+ G + VV+ + +E + + + G +A+ A + E+ LKK ++ Sbjct: 15 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENL 69 Score = 36.0 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 57/176 (32%), Gaps = 47/176 (26%) Query: 8 LDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 L E++ LDA G++ ++ + L+ AL +A AN H+E Sbjct: 6 LSIEEER--FLDAAEYGNIPVVRKMLEEC---HSLNVNCVDYMGQNALQLAVANEHLEIT 60 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY---------- 116 +L+ + + + AL A G + +V+ + + Sbjct: 61 ELLLKKENLSRVGD---------------ALLLAISKGYVRIVEAILNHPAFAEGKRLAT 105 Query: 117 --------EADPFIRNKFGH------DAIFEAEN-SGKEEVETYFLKKYDVE-PED 156 + D + ++ G I A + E V T K +E P D Sbjct: 106 SPSQSELQQDDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHD 161 >3DEO-A nrPDB Length = 183 Score = 44.5 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 45/118 (38%), Gaps = 16/118 (13%) Query: 19 DARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANS 78 AR D +L + E E+ TAL A G + VR + E + + Sbjct: 51 AARKADEQALSQLL------EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 104 Query: 79 AEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAEN 136 + G TALH A+ + +VV+ L E AD + ++ G A+ A Sbjct: 105 RDMRG---------GLTALHMAAGYVRPEVVEALV-ELGADIEVEDERGLTALELARE 152 Score = 44.1 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 37/95 (38%), Gaps = 14/95 (14%) Query: 6 EPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIET 65 + +D+ + ++ A G ++ + + ++ TALHMAA E Sbjct: 70 DAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH----RDMRGGLTALHMAAGYVRPEV 125 Query: 66 VRYILETVSRANSAEDLKAFVNEVNKTGNTALHWA 100 V ++E L A + ++ G TAL A Sbjct: 126 VEALVE----------LGADIEVEDERGLTALELA 150 >6MHW-A nrPDB Length = 826 Score = 44.1 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 40/211 (18%), Positives = 79/211 (37%), Gaps = 28/211 (13%) Query: 3 LHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGH 62 L+ P +E ++ A D+ L + E + TAL++A Sbjct: 178 LNINPNTKEIVRILLAFAEENDI--LGRFINAEYTEE-------AYEGQTALNIAIERRQ 228 Query: 63 IETVRYILETVSRANSAEDLKAFVNEVNK-----TGNTALHWASLNGKLDVVKLLCDEYE 117 + ++ + N A AF N + G T L A+ + ++V+LL + + Sbjct: 229 GDIAALLIAAGADVN-AHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQ 287 Query: 118 ADPFIRNKFGHDAIFE----AENSG------KEEVETYFLKKYDVEPE-DDEEDTQTEGK 166 D R+ G++ + AE+ K + L+ + E E D T + Sbjct: 288 TDITSRDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQ 347 Query: 167 NSVQITKGTEIEQV-TKEATEA-LREETEKL 195 + ++ K ++ + ++E E LR + K Sbjct: 348 LAAKMGKAEILKYILSREIKEKRLRSLSRKF 378 >3UI2-A nrPDB Length = 244 Score = 44.1 bits (102), Expect = 5e-05, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 45/118 (38%), Gaps = 16/118 (13%) Query: 19 DARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANS 78 AR D +L + E E+ TAL A G + VR + E + + Sbjct: 52 AARKADEQALSQLL------EDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH 105 Query: 79 AEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAEN 136 + G TALH A+ + +VV+ L E AD + ++ G A+ A Sbjct: 106 RDMRG---------GLTALHMAAGYVRPEVVEALV-ELGADIEVEDERGLTALELARE 153 Score = 43.7 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 37/95 (38%), Gaps = 14/95 (14%) Query: 6 EPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIET 65 + +D+ + ++ A G ++ + + ++ TALHMAA E Sbjct: 71 DAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDH----RDMRGGLTALHMAAGYVRPEV 126 Query: 66 VRYILETVSRANSAEDLKAFVNEVNKTGNTALHWA 100 V ++E L A + ++ G TAL A Sbjct: 127 VEALVE----------LGADIEVEDERGLTALELA 151 >6CUD-A nrPDB Length = 806 Score = 43.3 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 14/91 (15%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G+I VR +LE N VN V+ G AL A N L+V +LL + Sbjct: 34 AAEYGNIPVVRKMLEESKTLN--------VNCVDYMGQNALQLAVGNEHLEVTELLLKKE 85 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFL 147 + G DA+ A + G + L Sbjct: 86 NLA-----RIG-DALLLAISKGYVRIVEAIL 110 Score = 39.8 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 99 WASLNGKLDVV-KLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDV 152 A+ G + VV K+L + + + G +A+ A + EV LKK ++ Sbjct: 33 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENL 87 Score = 39.5 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 56/176 (31%), Gaps = 47/176 (26%) Query: 8 LDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 L E++ LDA G++ ++ + + L+ AL +A N H+E Sbjct: 24 LTAEEER--FLDAAEYGNIPVVRKMLE---ESKTLNVNCVDYMGQNALQLAVGNEHLEVT 78 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYE--------- 117 +L+ + A + AL A G + +V+ + + Sbjct: 79 ELLLKKENLARIGD---------------ALLLAISKGYVRIVEAILNHPGFAASKRLTL 123 Query: 118 ---------ADPFIRNKFGH------DAIFEAEN-SGKEEVETYFLKKYDVE-PED 156 D + ++ G I A + E V +K +E P D Sbjct: 124 SPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHD 179 >6DJS-A nrPDB Length = 676 Score = 42.5 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 37/91 (40%), Gaps = 14/91 (15%) Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEY 116 AA G+I VR +LE N VN V+ G AL A N L+V +LL + Sbjct: 51 AAEYGNIPVVRKMLEESKTLN--------VNCVDYMGQNALQLAVGNEHLEVTELLLKKE 102 Query: 117 EADPFIRNKFGHDAIFEAENSGKEEVETYFL 147 + G DA+ A + G + L Sbjct: 103 NLA-----RIG-DALLLAISKGYVRIVEAIL 127 Score = 39.5 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 99 WASLNGKLDVV-KLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKKYDV 152 A+ G + VV K+L + + + G +A+ A + EV LKK ++ Sbjct: 50 DAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENL 104 Score = 38.3 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 30/176 (17%), Positives = 56/176 (31%), Gaps = 47/176 (26%) Query: 8 LDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 L E++ LDA G++ ++ + + L+ AL +A N H+E Sbjct: 41 LTAEEER--FLDAAEYGNIPVVRKMLE---ESKTLNVNCVDYMGQNALQLAVGNEHLEVT 95 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYE--------- 117 +L+ + A + AL A G + +V+ + + Sbjct: 96 ELLLKKENLARIGD---------------ALLLAISKGYVRIVEAILNHPGFAASKRLTL 140 Query: 118 ---------ADPFIRNKFGH------DAIFEAEN-SGKEEVETYFLKKYDVE-PED 156 D + ++ G I A + E V +K +E P D Sbjct: 141 SPCEQELQDDDFYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGARIERPHD 196 >6C8G-A nrPDB Length = 675 Score = 42.5 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 69/193 (35%), Gaps = 25/193 (12%) Query: 7 PLDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLST---CKESESDSTALHMAAAN-- 60 P+ + ++ D + G L+ L++ + T +E+ + T L A N Sbjct: 9 PVIKMFNRHMLFDIVSRGSTAELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLN 68 Query: 61 -GHIETVRYILETVSR-ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEA 118 G +T+ +++ + N E + + +V G TALH A V+LL ++ A Sbjct: 69 GGKNDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEK-GA 127 Query: 119 DPFIRNK--------------FGHDAIFEAENSGKEEVETYFLKKY--DVEPEDDEEDTQ 162 D + + FG + A + + ++ Y + + + Sbjct: 128 DVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGN 187 Query: 163 TEGKNSVQITKGT 175 T V I T Sbjct: 188 TVLHALVAIADNT 200 >6BBJ-A nrPDB Length = 868 Score = 42.5 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 35/193 (18%), Positives = 69/193 (35%), Gaps = 25/193 (12%) Query: 7 PLDQEDQDTIILDARA-GDLDSLKDIFTTLVSPELLST---CKESESDSTALHMAAAN-- 60 P+ + ++ D + G L+ L++ + T +E+ + T L A N Sbjct: 140 PVIKMFNRHMLFDIVSRGSTAELEGFLPFLLAQKKRLTDEEFREASTGKTCLTKALMNLN 199 Query: 61 -GHIETVRYILETVSR-ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEA 118 G +T+ +++ + N E + + +V G TALH A V+LL ++ A Sbjct: 200 GGKNDTIPMLIDIAEKTGNLREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEK-GA 258 Query: 119 DPFIRNK--------------FGHDAIFEAENSGKEEVETYFLKKY--DVEPEDDEEDTQ 162 D + + FG + A + + ++ Y + + + Sbjct: 259 DVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIVHYLTENAHKKADIRRQDSRGN 318 Query: 163 TEGKNSVQITKGT 175 T V I T Sbjct: 319 TVLHALVAIADNT 331 >3W9G-A nrPDB Length = 260 Score = 40.6 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 69/186 (37%), Gaps = 25/186 (13%) Query: 14 DTIILDARA-GDLDSLKDIFTTLVSPELLST---CKESESDSTALHMAAAN---GHIETV 66 I+ D + G D L+ + + L++ + T +E + T L A N G +T+ Sbjct: 6 RPILFDIVSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRNDTI 65 Query: 67 RYILETVSR-ANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNK 125 +L+ + N E + + +V G TALH A V+LL ++ AD + + Sbjct: 66 PILLDIAEKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEK-GADVHAQAR 124 Query: 126 --------------FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEED--TQTEGKNSV 169 FG + A + + + Y + + + +D T V Sbjct: 125 GRFFQPKDEGGYFYFGELPLSLAACTNQPHIVHYLTENGHKQADLRRQDSRGNTVLHALV 184 Query: 170 QITKGT 175 I T Sbjct: 185 AIADNT 190 >5UIL-A nrPDB Length = 405 Score = 40.6 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 38/100 (38%), Gaps = 7/100 (7%) Query: 49 SDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDV 108 + + +AA +G+IE +++++ + N V K + +G Sbjct: 310 YGWSPVIVAAYHGNIELIKWLVSKGANINDRNYKGTTVAMYFK------DYMLKSGDYSG 363 Query: 109 VKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLK 148 +K+L D D + + + E SG + + Y + Sbjct: 364 LKMLID-LGLDLTLTDYKDYTVFDYLEKSGNKNLLQYMMA 402 >5AN8-A nrPDB Length = 613 Score = 39.1 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 40/112 (35%), Gaps = 22/112 (19%) Query: 53 ALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLD----- 107 L +AA + V Y+LE A A + + GNT LH + Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPA-------ASLQAQDSLGNTVLHALVMIADNSPENSA 188 Query: 108 -VVKL----LCDEYEADPFIR-----NKFGHDAIFEAENSGKEEVETYFLKK 149 VV++ L P ++ N G + A GK E+ + L++ Sbjct: 189 LVVRMYDGLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQR 240 Score = 36.0 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 35/174 (20%), Positives = 58/174 (33%), Gaps = 26/174 (14%) Query: 22 AGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRAN-SAE 80 AG L+ L+ L E + T L M A + V ++ + + + Sbjct: 16 AGLLEYLRRTSKYLTDSEYTEGS----TGKTCL-MKAVLNLQDGVNACIQPLLEIDRDSG 70 Query: 81 DLKAFVNEVNKT----GNTALHWASLNGKLDVVKLLCDEYEADPFI----------RNK- 125 + + VN G++ALH A L VKLL E A+ ++ Sbjct: 71 NPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLV-ENGANVHAKACGHFFQKNQDTC 129 Query: 126 --FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEED--TQTEGKNSVQITKGT 175 FG + A + + +V Y L+ +D T V I + Sbjct: 130 FYFGELPLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNS 183 Score = 27.9 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 14/26 (53%) Query: 52 TALHMAAANGHIETVRYILETVSRAN 77 T L +AA G IE ++IL+ A Sbjct: 220 TPLKLAAKEGKIEIFKHILQREFSAP 245 >6OO7-A nrPDB Length = 786 Score = 38.7 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 39/112 (34%), Gaps = 22/112 (19%) Query: 53 ALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALH------WASLNGKL 106 L +AA + V Y+LE A + + GNT LH S Sbjct: 211 PLSLAACTKQWDVVNYLLENP-------HQPASLQAQDSLGNTVLHALVMIADDSAENSA 263 Query: 107 DVVKL----LCDEYEADPFIR-----NKFGHDAIFEAENSGKEEVETYFLKK 149 VV++ L P ++ N G + A GK E+ + L++ Sbjct: 264 LVVRMYDGLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQR 315 Score = 37.2 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 40/191 (20%), Positives = 66/191 (34%), Gaps = 26/191 (13%) Query: 5 SEP-LDQEDQDTIILDARAG---DLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAAN 60 S+P L++ D+D + G DL L + S E + T L M A Sbjct: 66 SQPDLNRFDRDRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCL-MKAVL 124 Query: 61 GHIETVRYILETVSRAN-SAEDLKAFVNEVNKT----GNTALHWASLNGKLDVVKLLCDE 115 + V ++ + + + + + VN G++ALH A L VKLL E Sbjct: 125 NLQDGVNACIQPLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLV-E 183 Query: 116 YEADPFI----------RNK---FGHDAIFEAENSGKEEVETYFLKKYDVEPEDDEED-- 160 A+ ++ FG + A + + +V Y L+ +D Sbjct: 184 NGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHQPASLQAQDSL 243 Query: 161 TQTEGKNSVQI 171 T V I Sbjct: 244 GNTVLHALVMI 254 Score = 29.8 bits (65), Expect = 0.87, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 25/69 (36%), Gaps = 5/69 (7%) Query: 9 DQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRY 68 D + +++ G L + L L E T L +AA G IE ++ Sbjct: 257 DSAENSALVVRMYDGLLQA----GARLCPNVQLEGIPNLEGL-TPLKLAAKEGKIEIFKH 311 Query: 69 ILETVSRAN 77 IL+ A Sbjct: 312 ILQREFSAP 320 >6BO5-A nrPDB Length = 695 Score = 37.5 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 44/203 (21%), Positives = 69/203 (33%), Gaps = 35/203 (17%) Query: 1 MGLHSEPLDQEDQDTI-------ILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTA 53 +G + D+ D+D + + + G L+ L+ L S E + T Sbjct: 25 LGFEAPTPDRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTD----SAYTEGSTGKTC 80 Query: 54 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKT----GNTALHWASLNGKLDVV 109 L A N I+ + + + K VN G++ALH A L V Sbjct: 81 LMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCV 140 Query: 110 KLLCDEYEADPFIRN-------------KFGHDAIFEAENSGKEEVETYFL----KKYDV 152 KLL E AD +R FG + A + + +V TY L + + Sbjct: 141 KLLV-ENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASL 199 Query: 153 EPEDDEEDTQTEGKNSVQITKGT 175 E D + T V I + Sbjct: 200 EATDSLGN--TVLHALVMIADNS 220 Score = 34.5 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 41/117 (35%), Gaps = 22/117 (18%) Query: 53 ALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASL--NGKLDVVK 110 L +AA + V Y+LE A + + GNT LH + + + Sbjct: 173 PLSLAACTKQWDVVTYLLENP-------HQPASLEATDSLGNTVLHALVMIADNSPENSA 225 Query: 111 LLCDEYE--------ADPFIR-----NKFGHDAIFEAENSGKEEVETYFLKKYDVEP 154 L+ Y+ P ++ N G + A GK E+ + L++ P Sbjct: 226 LVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP 282 Score = 28.3 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 19/54 (35%), Gaps = 1/54 (1%) Query: 26 DSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 D L + L L + T L +AA G IE R+IL+ Sbjct: 232 DGLLQMGARLCPTVQLEEISNHQGL-TPLKLAAKEGKIEIFRHILQREFSGPYQ 284 >5HI9-A nrPDB Length = 770 Score = 36.8 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 45/200 (22%), Positives = 68/200 (34%), Gaps = 36/200 (18%) Query: 4 HSEPLDQEDQDTI-------ILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHM 56 EP D+ D+D + + + G L+ L+ L S E + T L Sbjct: 69 QQEP-DRFDRDRLFSVVSRGVPEELTGLLEYLRWNSKYLTD----SAYTEGSTGKTCLMK 123 Query: 57 AAANGHIETVRYILETVSRANSAEDLKAFVNEVNKT----GNTALHWASLNGKLDVVKLL 112 A N I+ + + + K VN G++ALH A L VKLL Sbjct: 124 AVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLL 183 Query: 113 CDEYEADPFIRN-------------KFGHDAIFEAENSGKEEVETYFL----KKYDVEPE 155 E AD +R FG + A + + +V TY L + +E Sbjct: 184 V-ENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEAT 242 Query: 156 DDEEDTQTEGKNSVQITKGT 175 D + T V I + Sbjct: 243 DSLGN--TVLHALVMIADNS 260 Score = 34.5 bits (77), Expect = 0.033, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 41/117 (35%), Gaps = 22/117 (18%) Query: 53 ALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASL--NGKLDVVK 110 L +AA + V Y+LE A + + GNT LH + + + Sbjct: 213 PLSLAACTKQWDVVTYLLENP-------HQPASLEATDSLGNTVLHALVMIADNSPENSA 265 Query: 111 LLCDEYE--------ADPFIR-----NKFGHDAIFEAENSGKEEVETYFLKKYDVEP 154 L+ Y+ P ++ N G + A GK E+ + L++ P Sbjct: 266 LVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQREFSGP 322 Score = 28.3 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 19/54 (35%), Gaps = 1/54 (1%) Query: 26 DSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 79 D L + L L + T L +AA G IE R+IL+ Sbjct: 272 DGLLQMGARLCPTVQLEEISNHQGL-TPLKLAAKEGKIEIFRHILQREFSGPYQ 324 >2ETB-A nrPDB Length = 256 Score = 36.8 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 40/178 (22%), Positives = 59/178 (33%), Gaps = 28/178 (15%) Query: 19 DARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANS 78 + G L+ L+ L S E + T L A N I+ + Sbjct: 16 EELTGLLEYLRWNSKYLTD----SAYTEGSTGKTCLMKAVLNLQDGVNACIMPLLQIDKD 71 Query: 79 AEDLKAFVNEVNKT----GNTALHWASLNGKLDVVKLLCDEYEADPFIRN---------- 124 + + K VN G++ALH A L VKLL E AD +R Sbjct: 72 SGNPKPLVNAQCTDEFYQGHSALHIAIEKRSLQCVKLLV-ENGADVHLRACGRFFQKHQG 130 Query: 125 ---KFGHDAIFEAENSGKEEVETYFL----KKYDVEPEDDEEDTQTEGKNSVQITKGT 175 FG + A + + +V TY L + +E D + T V I + Sbjct: 131 TCFYFGELPLSLAACTKQWDVVTYLLENPHQPASLEATDSLGN--TVLHALVMIADNS 186 Score = 34.5 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 40/112 (35%), Gaps = 22/112 (19%) Query: 53 ALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASL--NGKLDVVK 110 L +AA + V Y+LE A + + GNT LH + + + Sbjct: 139 PLSLAACTKQWDVVTYLLENP-------HQPASLEATDSLGNTVLHALVMIADNSPENSA 191 Query: 111 LLCDEYE--------ADPFIR-----NKFGHDAIFEAENSGKEEVETYFLKK 149 L+ Y+ P ++ N G + A GK E+ + L++ Sbjct: 192 LVIHMYDGLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 243 Score = 27.9 bits (60), Expect = 3.1, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 19/46 (41%), Gaps = 1/46 (2%) Query: 26 DSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILE 71 D L + L L + T L +AA G IE R+IL+ Sbjct: 198 DGLLQMGARLCPTVQLEEISNHQGL-TPLKLAAKEGKIEIFRHILQ 242 >6G1K-A nrPDB Length = 921 Score = 36.8 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 34/189 (17%), Positives = 61/189 (32%), Gaps = 22/189 (11%) Query: 13 QDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILET 72 + + + GD S+K ++ TAL +A N ++E + +L Sbjct: 33 EKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLL-- 90 Query: 73 VSRANSAEDLKAFVNEVNKTGNTALHWASLN--GKLDVVKLLCDEYEADPFIRNKFGHDA 130 S D G L G+ V +L D+ +D Sbjct: 91 -SFNVYVGDALLHAIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTP----DITP 145 Query: 131 IFEAENSGKEEVETYFLKKYDVEPEDDEEDTQTEGKNSVQITKGTEIEQVTKEATEALRE 190 I A ++ E+ ++K P+ E + +E V+ ++LR Sbjct: 146 IILAAHTNNYEIIKMLVQKGVSVPQPHE-------------VRCNCVECVSSSDVDSLRH 192 Query: 191 ETEKLNINK 199 +LNI K Sbjct: 193 SRSRLNIYK 201 >2F37-A nrPDB Length = 251 Score = 36.4 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 60/186 (32%), Gaps = 23/186 (12%) Query: 12 DQDTIILDARAG---DLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRY 68 D+D + G DL L + + S E + T L A N Sbjct: 7 DRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNAC 66 Query: 69 ILETVSRANSAEDLKAFVNEVNKT----GNTALHWASLNGKLDVVKLLCDEYEADPFIRN 124 IL + + + + VN G++ALH A L VKLL E A+ R Sbjct: 67 ILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLV-ENGANVHARA 125 Query: 125 -------------KFGHDAIFEAENSGKEEVETYFLKK--YDVEPEDDEEDTQTEGKNSV 169 FG + A + + +V +Y L+ + + T V Sbjct: 126 CGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALV 185 Query: 170 QITKGT 175 I+ + Sbjct: 186 MISDNS 191 Score = 32.5 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 39/112 (34%), Gaps = 22/112 (19%) Query: 53 ALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASL--NGKLDVVK 110 L +AA + V Y+LE A + + GNT LH + + + + Sbjct: 144 PLSLAACTKQWDVVSYLLENP-------HQPASLQATDSQGNTVLHALVMISDNSAENIA 196 Query: 111 LLCDEY------EADP-------FIRNKFGHDAIFEAENSGKEEVETYFLKK 149 L+ Y A IRN + A GK E+ + L++ Sbjct: 197 LVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248 Score = 29.1 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 26 DSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILE 71 D L L L + + D T L +AA G IE R+IL+ Sbjct: 203 DGLLQAGARLCPTVQLEDIRNLQ-DLTPLKLAAKEGKIEIFRHILQ 247 >4XD0-A nrPDB Length = 417 Score = 33.7 bits (75), Expect = 0.062, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 39/113 (34%), Gaps = 8/113 (7%) Query: 30 DIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEV 89 + + L+ E + K S + +AA +G+++ + +++ N V Sbjct: 305 EFISKLLKTENILFEKNHLGWS-PIIIAAYHGNMDVIEWLVSKGVNINDRNYKGTTVAMY 363 Query: 90 NKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEV 142 K + +G ++ L D F+++ G + E+ Sbjct: 364 FK------DYMLRSGNYTGLENLI-NLGLDLFLKDNEGLSVFDYMRKNKNIEL 409 >5Z6P-A nrPDB Length = 765 Score = 30.6 bits (67), Expect = 0.47, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 28/92 (30%) Query: 2 GLHSEPLDQEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANG 61 GL ED ++ + +K + L C+ ++ + AA Sbjct: 576 GLTHNSAQVEDYALLLEAFASEYFRVVKQELKKQLPNHLYLGCRFADWGMNPEVVRAAAK 635 Query: 62 HIETVRYILETVSRANSAEDLKAFVNEVNKTG 93 H++ V Y A ++ + G Sbjct: 636 HVDVVSYNYYKEGLHPEPWSFLADIDMPSIIG 667 >1GO3-E nrPDB Length = 187 Score = 29.1 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 25/86 (29%) Query: 10 QEDQDTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYI 69 +E I+++ G LD ++V + + K D +A H + Sbjct: 23 KETVKKILMEKYEGRLDKDVGFVLSIVDVKDIGEGKVVHGDGSAYHPVVFETLVYIPEMY 82 Query: 70 LETVSRANSAEDLKAFVNEVNKTGNT 95 + +FV G Sbjct: 83 ELIEGEVVDVVEFGSFVRLGPLDGLI 108 >2YCL-A nrPDB Length = 445 Score = 27.9 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 31/93 (33%), Gaps = 1/93 (1%) Query: 8 LDQEDQDTIILDARAGDLDSLKDI-FTTLVSPELLSTCKESESDSTALHMAAANGHIETV 66 L QD + D+ F + +PE L+ E+E + L AA + E + Sbjct: 133 LKGSSQDAATFAKAVATAREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQM 192 Query: 67 RYILETVSRANSAEDLKAFVNEVNKTGNTALHW 99 + + + + TAL + Sbjct: 193 VELAKKYNVPLTVSAKGLDALAELVQKITALGY 225 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.303 0.118 0.284 Lambda K H 0.267 0.0371 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,157,543 Number of Sequences: 36641 Number of extensions: 212334 Number of successful extensions: 1273 Number of sequences better than 10.0: 74 Number of HSP's better than 10.0 without gapping: 108 Number of HSP's successfully gapped in prelim test: 43 Number of HSP's that attempted gapping in prelim test: 586 Number of HSP's gapped (non-prelim): 362 length of query: 200 length of database: 10,336,785 effective HSP length: 92 effective length of query: 108 effective length of database: 6,965,813 effective search space: 752307804 effective search space used: 752307804 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 56 (26.3 bits)