BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46678 (594 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6F41-W nrPDB 1217 0.0 6CNF-S nrPDB 1117 0.0 5N9G-C nrPDB 77 1e-14 2UXN-B nrPDB 35 0.098 5LGU-B nrPDB 34 0.15 3ZN0-B nrPDB 34 0.18 4CZZ-B nrPDB 34 0.19 5LGN-B nrPDB 33 0.39 1MFU-A nrPDB 30 2.7 5K6L-A nrPDB 29 5.1 4GED-B nrPDB 29 6.5 >6F41-W nrPDB Length = 594 Score = 1217 bits (3150), Expect = 0.0, Method: Compositional matrix adjust. Identities = 594/594 (100%), Positives = 594/594 (100%) Query: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET Sbjct: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 Query: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT Sbjct: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 Query: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT Sbjct: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 Query: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE Sbjct: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 Query: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK Sbjct: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 Query: 301 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT 360 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT Sbjct: 301 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT 360 Query: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW Sbjct: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 Query: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN Sbjct: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 Query: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK Sbjct: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 Query: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ Sbjct: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 >6CNF-S nrPDB Length = 594 Score = 1117 bits (2890), Expect = 0.0, Method: Compositional matrix adjust. Identities = 551/594 (92%), Positives = 551/594 (92%) Query: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET Sbjct: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 Query: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT Sbjct: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 Query: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT Sbjct: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 Query: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE Sbjct: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 Query: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK Sbjct: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 Query: 301 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT 360 KAKLEKRRHLRELRMR T Sbjct: 301 KAKLEKRRHLRELRMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXT 360 Query: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW Sbjct: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 Query: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN Sbjct: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 Query: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK Sbjct: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 Query: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ Sbjct: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 >5N9G-C nrPDB Length = 175 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 46/137 (33%), Positives = 79/137 (57%), Gaps = 13/137 (9%) Query: 363 QLKLNPDGTMAIDEETMVVD--RHKNASIENEYKEKVDEN-PF---ANLYNYGSYGRGSY 416 ++K+ DG++ +DEE++ V+ R K + V+EN P + Y S+ + Y Sbjct: 26 RVKVAEDGSIILDEESLTVEVLRTKGPCV-------VEENDPIFERGSTTTYSSFRKNYY 78 Query: 417 TDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSK 476 + PW+ +E F+ A+SM GTDF++I QL+P+R+R ++K KF EEK I+ A + K Sbjct: 79 SKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEK 138 Query: 477 LPPNFDEYCCEIKKNIG 493 P +FD + ++K + Sbjct: 139 RPFDFDFFAHLLQKVLA 155 >2UXN-B nrPDB Length = 235 Score = 35.0 bits (79), Expect = 0.098, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 25/45 (55%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKK 464 WT EE + +A+ +G DF IS + +S QVK FVN ++ Sbjct: 136 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR 180 >5LGU-B nrPDB Length = 178 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 25/45 (55%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKK 464 WT EE + +A+ +G DF IS + +S QVK FVN ++ Sbjct: 79 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR 123 >3ZN0-B nrPDB Length = 482 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 25/45 (55%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKK 464 WT EE + +A+ +G DF IS + +S QVK FVN ++ Sbjct: 383 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR 427 Score = 33.9 bits (76), Expect = 0.22, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 21/35 (60%) Query: 416 YTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRS 450 + D WTVE+ + F +A S G F+ I Q+ P +S Sbjct: 188 FPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDKS 222 >4CZZ-B nrPDB Length = 553 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 27/50 (54%) Query: 416 YTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKR 465 + D WTVE+ + F +A S G F+ I Q+ P ++ + + + +K R Sbjct: 143 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTR 192 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKK 464 WT EE + + + +G DF I+ + ++ QVK FVN ++ Sbjct: 348 WTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRR 392 >5LGN-B nrPDB Length = 133 Score = 33.1 bits (74), Expect = 0.39, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 25/45 (55%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKK 464 WT EE + +A+ +G DF IS + +S QVK FVN ++ Sbjct: 76 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR 120 >1MFU-A nrPDB Length = 491 Score = 30.0 bits (66), Expect = 2.7, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 10/59 (16%) Query: 363 QLKLNPDGTMAIDEETMVVDRHKNASIEN--EYKEKVDENPFANLYNYGS----YGRGS 415 ++ +NPD T D V H+ I N ++ VD PF N Y+ GS +GRG+ Sbjct: 364 EVTINPDTTCGNDW----VCEHRWRQIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGN 418 >5K6L-A nrPDB Length = 921 Score = 29.3 bits (64), Expect = 5.1, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 7/40 (17%) Query: 386 NASIENEYKEKVDENPFANLYNYGSYGRGSYTDPWTVEEM 425 N +EN YKE +ENPF G G T+PW+ EM Sbjct: 84 NEELENIYKEWEEENPFDE-------GLGWGTEPWSQPEM 116 >4GED-B nrPDB Length = 113 Score = 28.9 bits (63), Expect = 6.5, Method: Compositional matrix adjust. Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 32 RTPQLFIPESKEIEEDNSDNDKGVDENETAIVEKPSLVGERSLEGFTLTGTNGHDNEIGD 91 R +LF + + GV N IV +PS +EGFT + N I Sbjct: 16 RGEKLFKGRAAQCHTATKGGSNGVGPNLFGIVNRPS----GKVEGFTYSKANAESGVIWT 71 Query: 92 EGPIDASTQNPK 103 +D +NPK Sbjct: 72 PEVLDVYLENPK 83 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6F41-W nrPDB 1088 0.0 6CNF-S nrPDB 1013 0.0 5N9G-C nrPDB 204 1e-52 Sequences not found previously or not previously below threshold: 5LGN-B nrPDB 38 0.014 3OSG-A nrPDB 37 0.018 5JPZ-A nrPDB 37 0.022 5CTQ-A nrPDB 37 0.022 2P4W-A nrPDB 36 0.034 5JJW-A nrPDB 36 0.041 5CTR-A nrPDB 36 0.041 2UXN-B nrPDB 36 0.043 3ZN0-B nrPDB 36 0.049 5LGU-B nrPDB 36 0.055 6NUW-I nrPDB 35 0.12 4GED-B nrPDB 32 1.00 1AVC-A nrPDB 32 1.0 4CZZ-B nrPDB 32 1.0 5K6L-A nrPDB 31 1.2 3OHM-B nrPDB 31 1.3 4CSV-A nrPDB 30 2.8 5XAF-E nrPDB 30 3.2 2K9N-A nrPDB 29 4.9 5TD8-B nrPDB 29 5.6 3ZQC-A nrPDB 29 5.9 2CU7-A nrPDB 29 6.9 4F61-I nrPDB 29 8.8 CONVERGED! >6F41-W nrPDB Length = 594 Score = 1088 bits (2813), Expect = 0.0, Method: Composition-based stats. Identities = 594/594 (100%), Positives = 594/594 (100%) Query: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET Sbjct: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 Query: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT Sbjct: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 Query: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT Sbjct: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 Query: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE Sbjct: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 Query: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK Sbjct: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 Query: 301 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT 360 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT Sbjct: 301 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT 360 Query: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW Sbjct: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 Query: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN Sbjct: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 Query: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK Sbjct: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 Query: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ Sbjct: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 >6CNF-S nrPDB Length = 594 Score = 1013 bits (2620), Expect = 0.0, Method: Composition-based stats. Identities = 551/594 (92%), Positives = 551/594 (92%) Query: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET Sbjct: 1 MSSIVNKSGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENET 60 Query: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT Sbjct: 61 AIVEKPSLVGERSLEGFTLTGTNGHDNEIGDEGPIDASTQNPKADVIEDNVTLKPAPLQT 120 Query: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT Sbjct: 121 HRDQKVPRSSRLASLSKDNESRPSFKPSFLDSSSNSNGTARRLSTISNKLPKKIRLGSIT 180 Query: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE Sbjct: 181 ENDMNLKTFKRHRVLGKPSSAKKPAGAHRISIVSKISPPTAMTDSLDRNEFSSETSTSRE 240 Query: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK Sbjct: 241 ADENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAK 300 Query: 301 KAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHT 360 KAKLEKRRHLRELRMR T Sbjct: 301 KAKLEKRRHLRELRMRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXT 360 Query: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW Sbjct: 361 AIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 Query: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN Sbjct: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 Query: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK Sbjct: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNK 540 Query: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ Sbjct: 541 KGSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDNEDNEGSEEEPEIDQ 594 >5N9G-C nrPDB Length = 175 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 47/155 (30%), Positives = 84/155 (54%), Gaps = 10/155 (6%) Query: 363 QLKLNPDGTMAIDEETMVVD--RHKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPW 420 ++K+ DG++ +DEE++ V+ R K + E + + Y S+ + Y+ PW Sbjct: 26 RVKVAEDGSIILDEESLTVEVLRTKGPCVVEENDPIFER---GSTTTYSSFRKNYYSKPW 82 Query: 421 TVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPN 480 + +E F+ A+SM GTDF++I QL+P+R+R ++K KF EEK I+ A + K P + Sbjct: 83 SNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKNKFKREEKTNGWRIDKAFQEKRPFD 142 Query: 481 FDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKE 515 FD + ++K + +K ++ H +KE Sbjct: 143 FDFFAHLLQKVLAEEEKRKQKSVK-----NHSLKE 172 >5LGN-B nrPDB Length = 133 Score = 37.8 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRS 475 WT EE + +A+ +G DF IS + +S QVK FVN ++ I+ L+ Sbjct: 76 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR--FNIDEVLQE 129 >3OSG-A nrPDB Length = 126 Score = 37.4 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 25/49 (51%) Query: 419 PWTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPI 467 PWT EE + + +G + +I++ +P R+ +K ++V K I Sbjct: 64 PWTAEEDALLVQKIQEYGRQWAIIAKFFPGRTDIHIKNRWVTISNKLGI 112 Score = 33.6 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 27/48 (56%) Query: 413 RGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVN 460 + + +T EE +A++ G+D+ +I+ +P R+ +Q + ++ N Sbjct: 7 KAAKKQKFTPEEDEMLKRAVAQHGSDWKMIAATFPNRNARQCRDRWKN 54 >5JPZ-A nrPDB Length = 509 Score = 37.0 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 36/174 (20%), Positives = 64/174 (36%), Gaps = 27/174 (15%) Query: 295 KSKMAKKAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEE------------------ 336 +S + + A+LEK L RQ PL+ + E EE Sbjct: 170 ESAIVEAARLEKVHSLFR-----RQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKAL 224 Query: 337 ---EKRKEERDKLLNADIPE-SDRKAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENE 392 EK K + LL A+ P ++ +A+ ++K+ + + E +V+ + Sbjct: 225 QQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIR 284 Query: 393 YKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLY 446 Y + +D + R PWTV ++ A+ G D +IS + Sbjct: 285 YSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTF 338 >5CTQ-A nrPDB Length = 561 Score = 37.0 bits (84), Expect = 0.022, Method: Composition-based stats. Identities = 36/174 (20%), Positives = 64/174 (36%), Gaps = 27/174 (15%) Query: 295 KSKMAKKAKLEKRRHLRELRMRARQEFKPLHSLTKEEQEEEE------------------ 336 +S + + A+LEK L RQ PL+ + E EE Sbjct: 185 ESAIVEAARLEKVHSLFR-----RQLAIPLYDMEATFAEYEEWSEDPIPESVIQNYNKAL 239 Query: 337 ---EKRKEERDKLLNADIPE-SDRKAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENE 392 EK K + LL A+ P ++ +A+ ++K+ + + E +V+ + Sbjct: 240 QQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIR 299 Query: 393 YKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLY 446 Y + +D + R PWTV ++ A+ G D +IS + Sbjct: 300 YSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTF 353 >2P4W-A nrPDB Length = 202 Score = 36.3 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 22/160 (13%) Query: 243 ENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAKKA 302 E + S+V+ IP+ G KY++ ++ + L P G SE +E + K Sbjct: 53 EEAGLIESRVEKIPR----GRPRKYYMIKKGLRLEILLTPTL-FG--SEMYEAKGVRKSP 105 Query: 303 KLEKRRHLRE------LRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDR 356 + E+ + L + ++MR EF LH L + +E EEKR+ E ++L E+ Sbjct: 106 EYEQAKELIKSQEPINVKMRELAEF--LHELNERIREIIEEKRELEEARILIETYIENTM 163 Query: 357 KAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENEYKEK 396 + +L + I+E +++ KEK Sbjct: 164 R-------RLAEENRQIIEEIFRDIEKILPPGYARSLKEK 196 >5JJW-A nrPDB Length = 300 Score = 36.3 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 47/114 (41%), Gaps = 1/114 (0%) Query: 334 EEEEKRKEERDKLLNADIPE-SDRKAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENE 392 ++ EK K + LL A+ P ++ +A+ ++K+ + + E +V+ + Sbjct: 12 QQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIR 71 Query: 393 YKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLY 446 Y + +D + R PWTV ++ A+ G D +IS + Sbjct: 72 YSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTF 125 >5CTR-A nrPDB Length = 338 Score = 36.3 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 47/114 (41%), Gaps = 1/114 (0%) Query: 334 EEEEKRKEERDKLLNADIPE-SDRKAHTAIQLKLNPDGTMAIDEETMVVDRHKNASIENE 392 ++ EK K + LL A+ P ++ +A+ ++K+ + + E +V+ + Sbjct: 17 QQLEKYKPYEEALLQAEAPRLAEYQAYIDFEMKIGDPARIQLIFERALVENCLVPDLWIR 76 Query: 393 YKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIKFYKALSMWGTDFNLISQLY 446 Y + +D + R PWTV ++ A+ G D +IS + Sbjct: 77 YSQYLDRQLKVKDLVLSVHNRAIRNCPWTVALWSRYLLAMERHGVDHQVISVTF 130 >2UXN-B nrPDB Length = 235 Score = 36.3 bits (82), Expect = 0.043, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRS 475 WT EE + +A+ +G DF IS + +S QVK FVN ++ I+ L+ Sbjct: 136 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR--FNIDEVLQE 189 >3ZN0-B nrPDB Length = 482 Score = 35.9 bits (81), Expect = 0.049, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRS 475 WT EE + +A+ +G DF IS + +S QVK FVN ++ I+ L+ Sbjct: 383 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR--FNIDEVLQE 436 >5LGU-B nrPDB Length = 178 Score = 35.9 bits (81), Expect = 0.055, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRS 475 WT EE + +A+ +G DF IS + +S QVK FVN ++ I+ L+ Sbjct: 79 WTTEEQLLAVQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRR--FNIDEVLQE 132 >6NUW-I nrPDB Length = 330 Score = 34.7 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 51/99 (51%), Gaps = 16/99 (16%) Query: 482 DEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEEDQTAQRLNDANLNKK 541 +E C ++K+ + D N+++I ++NE ++E++ K+ +++ A+ + LNK+ Sbjct: 200 NELCYQLKQVLARKEDLNQQIISVRNE----IQELKAGKDWHDLQNEQAKLNDKVKLNKR 255 Query: 542 GSGGIMTNDLKVYRKTEVVLGTIDDLKRKKLKERNNDDN 580 NDL T +LG + RK + + + DD+ Sbjct: 256 ------LNDL-----TSTLLGKYEG-DRKIMSQDSEDDS 282 >4GED-B nrPDB Length = 113 Score = 31.7 bits (70), Expect = 1.00, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 31/85 (36%), Gaps = 14/85 (16%) Query: 29 PKPRTP----------QLFIPESKEIEEDNSDNDKGVDENETAIVEKPSLVGERSLEGFT 78 PK R P +LF + + GV N IV +PS +EGFT Sbjct: 3 PKARAPLPPGDVERGEKLFKGRAAQCHTATKGGSNGVGPNLFGIVNRPS----GKVEGFT 58 Query: 79 LTGTNGHDNEIGDEGPIDASTQNPK 103 + N I +D +NPK Sbjct: 59 YSKANAESGVIWTPEVLDVYLENPK 83 >1AVC-A nrPDB Length = 673 Score = 31.7 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Query: 435 WGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPPNFDEYCCEIKKNIGT 494 WGTD + RS++ ++ F K IE ++R +L +F++ + K I + Sbjct: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251 Query: 495 VAD-FNEKLIE 504 A+ F E+L + Sbjct: 252 TAEYFAERLFK 262 >4CZZ-B nrPDB Length = 553 Score = 31.7 bits (70), Expect = 1.0, Method: Composition-based stats. Identities = 31/113 (27%), Positives = 46/113 (40%), Gaps = 17/113 (15%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKRPILIELALRSKLPP 479 WT EE + + + +G DF I+ + ++ QVK FVN + Sbjct: 348 WTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVN--------------YRRRF 393 Query: 480 NFDEYCCEIKKNIGTVADFNEKLIELQNEHKHHMKEIEEAKNTAKEED-QTAQ 531 N +E E + GT A N L E K + K+T +EE+ QT Q Sbjct: 394 NLEEVLQEWEAEQGTQAS-NGDASTLGEETK-SASNVPSGKSTDEEEEAQTPQ 444 >5K6L-A nrPDB Length = 921 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 7/44 (15%) Query: 384 HKNASIENEYKEKVDENPFANLYNYGSYGRGSYTDPWTVEEMIK 427 N +EN YKE +ENPF G G T+PW+ EM Sbjct: 82 TVNEELENIYKEWEEENPFDE-------GLGWGTEPWSQPEMEL 118 >3OHM-B nrPDB Length = 885 Score = 31.3 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 8/67 (11%) Query: 8 SGTRFAPKVRQRRAATGGTPTPKPRTPQLFIPESKEIEEDNSDNDKGVDENETAIVEKPS 67 S R P + A + + +P +PQL P +SD+ G+ E +EKPS Sbjct: 479 SAGRKRPLEQSNSALSESSAATEPSSPQLGSP--------SSDSCPGLSNGEEVGLEKPS 530 Query: 68 LVGERSL 74 L ++SL Sbjct: 531 LEPQKSL 537 >4CSV-A nrPDB Length = 275 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 356 RKAHTAIQLKLNPDGTMAIDE---ETMVVDRHKNASIENEYKEKVDENPFANLYNYGSYG 412 R + + +K +GTM+++E E ++ + K+ ++ Y E P + Y S+G Sbjct: 33 RNYNIEVAVKTLKEGTMSVEEFLQEAQIMKKLKHPNLVQLYGVCTKEPPIYIITEYMSHG 92 >5XAF-E nrPDB Length = 189 Score = 29.7 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 32/65 (49%) Query: 305 EKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDRKAHTAIQL 364 EKR H RE+ +A +E + KE+ ++ E KE R+ L A + K A ++ Sbjct: 118 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV 177 Query: 365 KLNPD 369 + N + Sbjct: 178 RKNKE 182 >2K9N-A nrPDB Length = 107 Score = 29.3 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 23/42 (54%) Query: 417 TDPWTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKF 458 TDPW+ EE + + + +G +N IS+ RS ++ ++ Sbjct: 53 TDPWSPEEDMLLDQKYAEYGPKWNKISKFLKNRSDNNIRNRW 94 >5TD8-B nrPDB Length = 198 Score = 29.0 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 38/88 (43%), Gaps = 12/88 (13%) Query: 422 VEEMIKFYKALSMWGTDFNLISQLYPYRSRKQ-VKAKFVNEEKKRPILIELALRSKLPPN 480 + KF++ + + DFN+ P R Q + + VN + R + + Sbjct: 91 NKICFKFFENIGV--QDFNMTDLYKPEAQRTQRLLSAVVNYAR---------FREERMFD 139 Query: 481 FDEYCCEIKKNIGTVADFNEKLIELQNE 508 + + +++ +G + N+++ +LQ + Sbjct: 140 CNSFILQMESLLGQINKLNDEIKQLQKD 167 >3ZQC-A nrPDB Length = 131 Score = 29.0 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 25/46 (54%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKAKFVNEEKKR 465 WT EE ++ G+ +++I++L P R+ +K ++ + KR Sbjct: 57 WTPEEDETIFRNYLKLGSKWSVIAKLIPGRTDNAIKNRWNSSISKR 102 >2CU7-A nrPDB Length = 72 Score = 29.0 bits (63), Expect = 6.9, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 4/48 (8%) Query: 420 WTVEEMIKFYKALSMWGTDFNLISQLYPYRSRKQVKA----KFVNEEK 463 WT+EE F + L+ +G + IS+L R+ QVK+ F N+ K Sbjct: 12 WTIEEKELFEQGLAKFGRRWTKISKLIGSRTVLQVKSYARQYFKNKVK 59 >4F61-I nrPDB Length = 240 Score = 28.6 bits (62), Expect = 8.8, Method: Composition-based stats. Identities = 30/133 (22%), Positives = 62/133 (46%), Gaps = 7/133 (5%) Query: 242 DENENYVISKVKDIPKKVRDGESAKYFIDEENFTMAELCKPNFPIGQISENFEKSKMAKK 301 + E + + ++ + +K + E + EEN ++ K + Q E+ ++++ ++ Sbjct: 107 ENREAHFAAMLERLQEKDKHAEEVRQRAIEENNNWIKMAKEK--LAQKMESNKENRKYQE 164 Query: 302 AKL-----EKRRHLRELRMRARQEFKPLHSLTKEEQEEEEEKRKEERDKLLNADIPESDR 356 A+L EKR H RE+ RA +E + KE+ ++ E KE R+ A + Sbjct: 165 AELLKHLAEKREHEREVIQRAIEENNNWIKMAKEKLAQKMESNKENREAHFAAMLERLQE 224 Query: 357 KAHTAIQLKLNPD 369 K A +++ N + Sbjct: 225 KDKHAEEVRKNKE 237 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.127 0.343 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,191,379 Number of Sequences: 36641 Number of extensions: 971568 Number of successful extensions: 3228 Number of sequences better than 10.0: 39 Number of HSP's better than 10.0 without gapping: 41 Number of HSP's successfully gapped in prelim test: 76 Number of HSP's that attempted gapping in prelim test: 2997 Number of HSP's gapped (non-prelim): 244 length of query: 594 length of database: 10,336,785 effective HSP length: 103 effective length of query: 491 effective length of database: 6,562,762 effective search space: 3222316142 effective search space used: 3222316142 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 62 (28.5 bits)