BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46597 (345 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4A6D-A nrPDB 714 0.0 6C5B-A nrPDB 112 2e-25 4Z2Y-A nrPDB 109 2e-24 3GXO-A nrPDB 98 4e-21 4D7K-A nrPDB 94 8e-20 5I2H-A nrPDB 93 1e-19 6IWT-A nrPDB 88 6e-18 4X3Q-A nrPDB 87 7e-18 5CVU-A nrPDB 86 2e-17 1FP1-D nrPDB 85 5e-17 1KYW-A nrPDB 84 9e-17 5XOH-A nrPDB 79 2e-15 5ICG-A nrPDB 79 3e-15 1ZG3-A nrPDB 77 9e-15 6CLW-A nrPDB 76 2e-14 4PGH-A nrPDB 75 3e-14 4EVI-A nrPDB 74 1e-13 3P9C-A nrPDB 73 2e-13 6I5Z-A nrPDB 72 3e-13 2QYO-A nrPDB 70 1e-12 2IP2-A nrPDB 70 2e-12 1FP2-A nrPDB 68 8e-12 3LST-A nrPDB 67 1e-11 1XDU-A nrPDB 64 7e-11 1X1B-A nrPDB 64 1e-10 4WXH-A nrPDB 61 6e-10 3MCZ-A nrPDB 56 2e-08 3I64-A nrPDB 49 3e-06 5W7R-A nrPDB 47 2e-05 3DP7-A nrPDB 45 6e-05 2R3S-A nrPDB 44 8e-05 4GEK-A nrPDB 43 2e-04 4IWN-A nrPDB 43 2e-04 4MWZ-A nrPDB 38 0.006 5F8E-A nrPDB 36 0.030 2B3T-A nrPDB 33 0.18 1IXC-A nrPDB 30 1.1 5GM1-A nrPDB 30 1.4 6DCC-A nrPDB 30 1.7 3L8C-A nrPDB 29 3.4 1I5N-A nrPDB 28 4.3 2AXR-A nrPDB 28 5.4 2LP4-A nrPDB 28 6.2 5GZA-A nrPDB 28 6.8 >4A6D-A nrPDB Length = 353 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT Sbjct: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 Query: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL Sbjct: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 Query: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF Sbjct: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180 Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD 240 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD Sbjct: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD 240 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS 300 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS Sbjct: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS 300 Query: 301 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK Sbjct: 301 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 >6C5B-A nrPDB Length = 341 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 86/318 (27%), Positives = 144/318 (45%), Gaps = 13/318 (4%) Query: 11 LLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 +L G+ V+Q L+ A +LG+ DL+A+AP P++ A G +A LL + ++ Sbjct: 15 ILLQMITGYWVTQSLYVAAKLGIADLVADAPKPIEELAAKTGAKAP-----LLKRVLRTI 69 Query: 71 KLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQ 130 + V T + T L++ L + +P S G YR W + V+ G Sbjct: 70 ASIGVFTETEPGIFGITPLAA-LLRSGTPDSMRPQAIMHGEEQYRAWADVLHNVQTGETA 128 Query: 131 YLETFGVPAEELFTAIYR-SEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGG 189 + + FG F + + E +R+ F +A +V+ A+D S F + D+G G Sbjct: 129 FEKEFGT---SYFGYLAKHPEADRV-FNEAQAGYTKQVAHAVVDAYDFSPFKTVIDIGAG 184 Query: 190 AGALAKECMSLYPGCKITVFDIPEVVWTAKQHFS-FQEEEQIDFQEGDFFKDPLPEADLY 248 G L + P + +FD P V A + + ++ GDFF + + D+Y Sbjct: 185 YGPLLSAILRSQPEARGILFDQPHVAQAAGKRLAEAGVGDRCGTVGGDFFVEVPADGDVY 244 Query: 249 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTE 308 IL+ +LHDW D + +L G +L++E +L E P + L+MLV Sbjct: 245 ILSLLLHDWDDQRSIEILRNCRRAMPAHGKLLIVELVLPEGEE-PFFGKWLDLHMLVLLG 303 Query: 309 GQERTPTHYHMLLSSAGF 326 QERT + L +++GF Sbjct: 304 AQERTADEFKTLFAASGF 321 >4Z2Y-A nrPDB Length = 359 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 97/315 (30%), Positives = 147/315 (46%), Gaps = 14/315 (4%) Query: 18 GFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVET 77 GF +Q L A L + DLLA+ G DV +A+ A A LL V L++L Sbjct: 25 GFFTAQTLHVAVRLRIPDLLAD--GARDVGDLASATGADAPSLRRLLRALVFLEVLDEPA 82 Query: 78 RGGKAFYRNTE-LSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFG 136 G A E L +D V+ + + +L G S+ WG L +VR G + G Sbjct: 83 PGTFALTEQGEVLRAD----VTGSMRELVLLLSGPESWAAWGQLEHSVRTGEVAWEHVHG 138 Query: 137 VPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKE 196 F + + F A+ E ++L+A+D + D+GGG+GAL Sbjct: 139 ---RSCFDHLMADPQRQAAFNAAMAEGSRAFVPTLLSAYDFGDLRTVVDVGGGSGALLAG 195 Query: 197 CMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEADLYILARVLH 255 ++ +P + TVFD P+ V A + + Q ++ + GDFF P AD Y+L VLH Sbjct: 196 VLAAHPHLRGTVFDTPDGVADAARTVAEQGVADRCGVETGDFFVSVPPGADAYVLKSVLH 255 Query: 256 DWADGKCSHLLERIYHTCKPGGGILVIESLLDED-RRGPLLTQ--LYSLNMLVQTEGQER 312 DW D +C +L + +P ++++ESL+ P + Q + LNM+V G+ER Sbjct: 256 DWDDEQCVEVLRTVRRAVRPDSRVILVESLMPTTVTTAPSVAQVVMNDLNMMVCHGGRER 315 Query: 313 TPTHYHMLLSSAGFR 327 T + LL AGFR Sbjct: 316 TVAEFRELLRVAGFR 330 >3GXO-A nrPDB Length = 369 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 87/318 (27%), Positives = 137/318 (43%), Gaps = 12/318 (3%) Query: 12 LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLK 71 +ND G ++ + A ELGV +LL E P A A G AH L + + Sbjct: 42 VNDILQGAWKARAIHVAVELGVPELLQEGPRTATALAEATG----AHEQTLRRLLRLLAT 97 Query: 72 LLKVETRGGKAFYRNTELSSDYLT-TVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQ 130 + + G + LS+ L SP + + + +R W L +VR G Sbjct: 98 VGVFDDLGHDDLFAQNALSAVLLPDPASPVATDARFQ-AAPWHWRAWEQLTHSVRTGEAS 156 Query: 131 YLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGA 190 + G + + R F +A+ V V A+D S D+GGG Sbjct: 157 FDVANGT---SFWQLTHEDPKARELFNRAMGSVSLTEAGQVAAAYDFSGAATAVDIGGGR 213 Query: 191 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEADLYI 249 G+L + +PG + T+ + P V A++ + + ++ + GDFF+ AD+Y+ Sbjct: 214 GSLMAAVLDAFPGLRGTLLERPPVAEEARELLTGRGLADRCEILPGDFFETIPDGADVYL 273 Query: 250 LARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEG 309 + VLHDW D +L RI KP +LVI++L+DE R T L +LV G Sbjct: 274 IKHVLHDWDDDDVVRILRRIATAMKPDSRLLVIDNLIDE--RPAASTLFVDLLLLVLVGG 331 Query: 310 QERTPTHYHMLLSSAGFR 327 ER+ + + LL +G R Sbjct: 332 AERSESEFAALLEKSGLR 349 >4D7K-A nrPDB Length = 353 Score = 94.0 bits (232), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 102/359 (28%), Positives = 147/359 (40%), Gaps = 44/359 (12%) Query: 5 EDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLL 64 E A + L Y V+ VL+A +L + DLLA+ P A A G S Sbjct: 10 ERTAAQRLYQYNVDLKVAFVLYAVAKLHLPDLLADGPRTTADLAAATGSDPS-------- 61 Query: 65 DICVSLKLLKVETRGGKAFYRNTELS------SDYLTTVSPTSQCSMLKYMGRTSY-RCW 117 L+ L G A E S D L + P S M + + Sbjct: 62 ----RLRRLLRAAAGADALREVPEDSFELAPMGDLLRSGHPRSMRGMTTFFAEPDVLAAY 117 Query: 118 GHLADAVREGRNQYLETFGVPA------EELFTAIYRSEGE--RLQFMQALQEVWSVNGR 169 G L ++VR G VPA E L+ + R + + R +F A+ E Sbjct: 118 GDLVESVRTG---------VPAFQLRHREPLYDFLARPQHKEVRDEFDAAMVEFGQYFAD 168 Query: 170 SVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EE 228 LT+FD F D+GGG G ++ P + D P V +A + + Q E Sbjct: 169 DFLTSFDFGRFTRFADIGGGRGQFLAGVLTAVPSSTGVLVDGPAVAASAHKFLASQNLTE 228 Query: 229 QIDFQEGDFFKDPLPEA-DLYILARVLHDWADGKCSHLLERIYHTC--KPGGGILVIESL 285 +++ + GDFF D LP D Y+L VL DWAD LL RI P +L+++S+ Sbjct: 229 RVEVRIGDFF-DVLPTGCDAYVLRGVLEDWADADAVRLLVRIRQAMGDAPEARLLILDSV 287 Query: 286 LDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILAR 344 + E L ++ L+MLV EG+ RT + LL+ AGF G ++ I R Sbjct: 288 IGETGE---LGKVLDLDMLVLVEGEHRTRAQWDDLLARAGFDIVGIHPAGDVWAVIECR 343 >5I2H-A nrPDB Length = 364 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 90/350 (25%), Positives = 154/350 (44%), Gaps = 26/350 (7%) Query: 14 DYANGFMVSQVLFAA-CELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKL 72 D G +++L A+ L VFD+L E+P LD + + S T++L+ +++L Sbjct: 22 DLFRGNFATELLAASVAHLHVFDILNESPLSLD--ELQRRLVLSERATQVLVTGLCAMQL 79 Query: 73 LKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQYL 132 L G T L+ ++L T SP S + +++ L + ++ R + Sbjct: 80 LTKRLAGEIDL---TPLARNHLVTTSPFSVGGYISLAAQSAGTL--ALVERLKSDRPEGA 134 Query: 133 ETFGVPA----EELFTAIYRSEGERLQFMQALQEVWSVNGR-----------SVLTAFDL 177 E+ A E +A+ R + R + W+V R +L Sbjct: 135 ESEQGAAFIFREGSESAMDREDSARFLTLSLAGRAWNVAPRFADVLPAGQPGKILKDNSG 194 Query: 178 SVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE--EEQIDFQEG 235 S ++ D+ GG+G + YP + +FD PEV+ A + + Q ++++ G Sbjct: 195 SSGRVLLDVAGGSGIYTMAVLQKYPTWRGIIFDRPEVLKIAAE-LAEQTGVRDRLELHAG 253 Query: 236 DFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLL 295 D + DP P AD +L+ VLHDW +C+ L+ + GG +L+ + LL+ D GPL Sbjct: 254 DMWVDPFPPADDILLSNVLHDWDRPQCARLVAKATSGLPEGGRLLIHDVLLNSDLTGPLE 313 Query: 296 TQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 LYSL + TEG+ + Y ++ A + T A IL+ K Sbjct: 314 IALYSLALFSLTEGRAYSLEEYRGWIAGADLKYVDCIPTSAHGHLILSEK 363 >6IWT-A nrPDB Length = 364 Score = 87.8 bits (216), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 86/345 (24%), Positives = 150/345 (43%), Gaps = 31/345 (8%) Query: 5 EDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEA-PGP-LDVAAVAAGVRASAHGTEL 62 E++A A+ ++ VL +A EL + + +A+A PG + + +AA + +S T + Sbjct: 17 EEEACMFAMQLASASVLPMVLKSAIELDLLESIAKAGPGAYVSPSELAAKLPSSQPDTPV 76 Query: 63 LLD----ICVSLKLLKVETR----GGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSY 114 +LD + S +LK + + GG +LT S + L M + Sbjct: 77 MLDRILRLLASYSVLKCKVQDLPQGGVERLYALAPVCKFLTKNSDGVSMAPLLLMNQDKI 136 Query: 115 --RCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSVNGRS 170 W HL DAV +G + + +G+ A E Y + R F + ++ + Sbjct: 137 LMESWYHLKDAVLDGGIPFNKAYGMTAFE-----YHGKDPRFNKVFNLGMSNHSTITMKK 191 Query: 171 VLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQ 229 +L ++ + + D+GGG GA +S YP K FD+P VV A + Sbjct: 192 ILQTYNGFAGLKTVVDVGGGTGATLNMIISKYPNIKGINFDLPHVVEDAPSY------PG 245 Query: 230 IDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDED 289 ++ GD F +PE D + + HDW+D C L+ Y G +++ E +L E Sbjct: 246 VEHVGGDMFVS-VPEGDAIFMKWICHDWSDAHCLSFLKNCYKALPQNGKVILAECILPEA 304 Query: 290 RRGPLLTQ-LYSLNMLV---QTEGQERTPTHYHMLLSSAGFRDFQ 330 L T+ + +++++ G+ERT + L AGF+ F Sbjct: 305 PDSKLTTKNVIHIDVIMLAHNPGGKERTEKEFEALGKMAGFKSFN 349 >4X3Q-A nrPDB Length = 355 Score = 87.4 bits (215), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 80/285 (28%), Positives = 129/285 (45%), Gaps = 11/285 (3%) Query: 18 GFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVET 77 G Q L A C+LG+F+LL E GPL VA +R ++LL +L L V T Sbjct: 14 GHAAFQQLNAGCQLGLFELLHER-GPLSAEEVADALRLPRRSADILLLGTTALGLSTV-T 71 Query: 78 RGGKAFYRN-TELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFG 136 GG YRN + + + + P + +++Y + +Y+ +++R G+N + F Sbjct: 72 DGG---YRNGAPIGAAFRDGLWPVLR-DIVQYQDKIAYQPAADYVESLRTGQNAGIRHFP 127 Query: 137 VPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTA-FDLSVFPLMCDLGGGAGALAK 195 +L++ + G F + + WS VL A D + + D+GGG A Sbjct: 128 GTTRDLYSRLAAVPGLEELFYRGMH-AWSQLSNPVLLAQPDFTRVHRVLDVGGGDAVNAV 186 Query: 196 ECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEA-DLYILARV 253 +P ++TV D P + A++ + EE++ D F D P D + A Sbjct: 187 ALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFTDSYPAGHDCVLFAHQ 246 Query: 254 LHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQL 298 L W+ + LL + Y +PGG +LV + D+DR GPL L Sbjct: 247 LVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDDDRTGPLYAAL 291 >5CVU-A nrPDB Length = 368 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 81/351 (23%), Positives = 154/351 (43%), Gaps = 38/351 (10%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGP---LDVAAVAAGVRASAHG 59 SS+++A A+ ++ L AA EL V +++A++ P + A +AA + + Sbjct: 16 SSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPE 75 Query: 60 TELLLDICVSLKLLKVETRGGKAFYRNTELSS---DYLTTVSPTSQ--------CSMLKY 108 ++LD ++L++ Y EL S + L ++P + S+ + Sbjct: 76 APVMLD-----RVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPF 130 Query: 109 M----GRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVW 164 + + W +L DA+ EG + + +G+ + F +R F + + Sbjct: 131 LLLATDKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINK---VFNKGMSSNS 187 Query: 165 SVNGRSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFS 223 ++ + +L ++ + D+GGG GA+A ++ YP FD+P V+ A + Sbjct: 188 TITMKKILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAP---A 244 Query: 224 FQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 F E + GD F D +P+ D + + HDW+D C LL+ Y G ++V E Sbjct: 245 FSGVEHLG---GDMF-DGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAE 300 Query: 284 SLLDEDRRGPLLTQLY----SLNMLVQTEGQERTPTHYHMLLSSAGFRDFQ 330 +L + T++ +L + G+ERT + L ++GFR F+ Sbjct: 301 YILPPSPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFK 351 >1FP1-D nrPDB Length = 372 Score = 84.7 bits (208), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 83/330 (25%), Positives = 144/330 (43%), Gaps = 36/330 (10%) Query: 24 VLFAACELGVFDLLAEAPGP---LDVAAVAAGVRASAHGTEL------LLDICVSLKLLK 74 VL AA +L +F+++A+A P + + +A+ + AS ++L +L + S +L Sbjct: 40 VLNAAIDLNLFEIIAKATPPGAFMSPSEIASKLPASTQHSDLPNRLDRMLRLLASYSVLT 99 Query: 75 VETR----GGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSY----RCWGHLADAV-R 125 TR GG + YL V S+ + + Y + W + +AV Sbjct: 100 STTRTIEDGGAERVYGLSMVGKYL--VPDESRGYLASFTTFLCYPALLQVWMNFKEAVVD 157 Query: 126 EGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFD-LSVFPLMC 184 E + + GV E + + F +++ +V + + +L + + Sbjct: 158 EDIDLFKNVHGVTKYEFMG---KDKKMNQIFNKSMVDVCATEMKRMLEIYTGFEGISTLV 214 Query: 185 DLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPE 244 D+GGG+G + +S YP K FD+P+V+ A I+ GD F +P+ Sbjct: 215 DVGGGSGRNLELIISKYPLIKGINFDLPQVIENAPPL------SGIEHVGGDMFAS-VPQ 267 Query: 245 ADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDED----RRGPLLTQLYS 300 D IL V H+W+D KC L + P G ++++E +L E+ L++ L + Sbjct: 268 GDAMILKAVCHNWSDEKCIEFLSNCHKALSPNGKVIIVEFILPEEPNTSEESKLVSTLDN 327 Query: 301 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQ 330 L M + G+ERT Y L +GF FQ Sbjct: 328 L-MFITVGGRERTEKQYEKLSKLSGFSKFQ 356 >1KYW-A nrPDB Length = 365 Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 85/349 (24%), Positives = 150/349 (42%), Gaps = 37/349 (10%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEA-PG----PLDVAAVAAGVRASAH 58 S+++A A+ ++ +L +A EL + +++A+A PG P+++A+ A Sbjct: 15 SDEEANLFAMQLASASVLPMILKSALELDLLEIIAKAGPGAQISPIEIASQLPTTNPDA- 73 Query: 59 GTELLLD------ICVSLKLLKVETRGGKAFYRNTELSS--DYLTTVSPTSQCSMLKYMG 110 ++LD C + V T+ R L++ YL S L M Sbjct: 74 --PVMLDRMLRLLACYIILTCSVRTQQDGKVQRLYGLATVAKYLVKNEDGVSISALNLMN 131 Query: 111 --RTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSV 166 + W HL DAV +G + + +G+ A E Y R F + + + ++ Sbjct: 132 QDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFE-----YHGTDPRFNKVFNKGMSDHSTI 186 Query: 167 NGRSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQ 225 + +L + + D+GGG GA+ +S YP K FD+P V+ A S+ Sbjct: 187 TMKKILETYTGFEGLKSLVDVGGGTGAVINTIVSKYPTIKGINFDLPHVIEDAP---SYP 243 Query: 226 EEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESL 285 E + GD F +P+AD + + HDW+D C L+ Y G ++V E + Sbjct: 244 GVEHVG---GDMFVS-IPKADAVFMKWICHDWSDEHCLKFLKNCYEALPDNGKVIVAECI 299 Query: 286 LDEDRRGPLLTQ-LYSLNMLV---QTEGQERTPTHYHMLLSSAGFRDFQ 330 L L T+ + +++++ G+ERT + L AGF+ F+ Sbjct: 300 LPVAPDSSLATKGVVHIDVIMLAHNPGGKERTQKEFEDLAKGAGFQGFK 348 >5XOH-A nrPDB Length = 359 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 82/358 (22%), Positives = 154/358 (43%), Gaps = 52/358 (14%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEA-PG----PLDVAAVAAGVRASA 57 S +++A L A ++ +L +A EL + + +++A PG P D+A+ + ++ Sbjct: 9 SQDEEACVLAIQLATSTVLPMILKSAIELDILNTISKAGPGNYLSPSDLASKL--LMSNP 66 Query: 58 HGTELLLDICVSLKLLKV------ETRGGKA-----------FYRNTELSSDYLTTVSPT 100 H +L I L KV E G+ F N E + +++P Sbjct: 67 HAPIMLERILRVLATYKVLGCKPSELSDGEVEWLYCWTPVCKFLSNNEDGA----SIAPL 122 Query: 101 SQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQ 158 +L + + + W HL DA+ +G + + +G+ +F Y S+ + F + Sbjct: 123 ----LLVHQDQVPMKSWYHLTDAILDGGTAFNKAYGM---NIFD--YASQDPQFNKVFNR 173 Query: 159 ALQEVWSVNGRSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWT 217 ++ ++ + +L ++ + D+GGG+GA +S YP K FD+P VV Sbjct: 174 SMAGHSTITMKKILETYNGFEGLKSIVDVGGGSGATLNMIISKYPTIKGINFDLPHVVGD 233 Query: 218 AKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGG 277 + H ++ GD F +P+ D L + H W+D C +L+ Y Sbjct: 234 SPIH------PGVEHVGGDMFAS-VPKGDAIFLKWIFHSWSDEDCLRILKNCYEALADNK 286 Query: 278 GILVIESLLDE-----DRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQ 330 ++V E ++ E D + L ++ + G+ERT + L +SAGF+ F+ Sbjct: 287 KVIVAEFIIPEVPGGSDDATKSVVHLDAVMLAYVPGGKERTEKEFEALATSAGFKSFR 344 >5ICG-A nrPDB Length = 352 Score = 79.0 bits (193), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 82/347 (23%), Positives = 154/347 (44%), Gaps = 29/347 (8%) Query: 12 LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELL---LDICV 68 L ++ GF S VL +A +L + +++ P+ ++ ++ + + + L L V Sbjct: 17 LWNFIYGFADSLVLKSAVQLDLANIIHNHGSPMTLSELSLHLPSQPVNQDALYRVLRYLV 76 Query: 69 SLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQC---SMLKYMGRTSYRCWGHLADAVR 125 +KL + G+ Y L+ V +C ++L + W +L + Sbjct: 77 HMKLFTKSSIDGELRYG---LAPPAKFLVKGWDKCMLGAILTITDKDFMAPWHYL----K 129 Query: 126 EGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDL---SVF-- 180 EG T + L T I+ E + Q E + + R +++A S+F Sbjct: 130 EGILNDGSTSTAFEKALGTNIWDYMAEHPEKNQLFNEGMANDTRLIMSALVKECSSMFDG 189 Query: 181 -PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFK 239 + D+GGG G + +P K TV+D+P V+ + + +I+ +GD FK Sbjct: 190 ITTIVDVGGGTGTAVRNIAKAFPHIKCTVYDLPHVIADSPGY------TEINSIQGDMFK 243 Query: 240 DPLPEADLYILARVLHDWADGKCSHLLERIYHTC-KPGGGILVIESLLDEDRRGPL--LT 296 +P AD ++ +LHDW D +C +L+R + GG +++I+ +LD P + Sbjct: 244 -YIPNADAIMMKCILHDWDDKECIEILKRCKDAVPRDGGKVIIIDIILDVKSEHPYTKMR 302 Query: 297 QLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILA 343 L+M++ T G+ERT + L+ AG++ ++ A+ I A Sbjct: 303 LTLDLDMMLNTGGKERTEEEWKKLIHDAGYKGYKITHISAVQSVIEA 349 >1ZG3-A nrPDB Length = 358 Score = 77.4 bits (189), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 97/363 (26%), Positives = 153/363 (42%), Gaps = 52/363 (14%) Query: 2 GSSEDQAYRL---LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAH 58 GS E + Y L + F+ S L +A ELG+ D + P+ ++ +A+ ++ Sbjct: 1 GSEESELYHAQIHLYKHVYNFVSSMALKSAMELGIADAIHNHGKPMTLSELASSLKLHPS 60 Query: 59 GTELLLDICVSLKLLKVETRGGKAFYRNTELS-----------------SDYLTTVSPTS 101 +L + L++ T G F+ T + S L + PT Sbjct: 61 KVNILH------RFLRLLTHNG--FFAKTIVKGKEGDEEEEIAYSLTPPSKLLISGKPTC 112 Query: 102 QCSMLK-YMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQAL 160 S++K + +S W E + Q L F E F + E + Sbjct: 113 LSSIVKGALHPSSLDMWSSSKKWFNEDKEQTL--FECATGESFWDFLNKDSES-STLSMF 169 Query: 161 QEVWSVNGR--SVLTAFDLSVFP---LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVV 215 Q+ + + R ++ + VF + D+GGG G + K ++P K TVFD P+VV Sbjct: 170 QDAMASDSRMFKLVLQENKRVFEGLESLVDVGGGTGGVTKLIHEIFPHLKCTVFDQPQVV 229 Query: 216 WTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLL----ERIYH 271 + E ++F GD FK +P AD +L VLHDW D + +L E I H Sbjct: 230 G------NLTGNENLNFVGGDMFKS-IPSADAVLLKWVLHDWNDEQSLKILKNSKEAISH 282 Query: 272 TCKPGGGILVIESLLDE--DRRGPLLTQL-YSLNMLVQTEGQERTPTHYHMLLSSAGFRD 328 K G +++I+ +DE D RG QL Y L ML G+ERT + L+ AGF Sbjct: 283 KGK-DGKVIIIDISIDETSDDRGLTELQLDYDLVMLTMFLGKERTKQEWEKLIYDAGFSS 341 Query: 329 FQF 331 ++ Sbjct: 342 YKI 344 >6CLW-A nrPDB Length = 364 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 96/314 (30%), Positives = 130/314 (41%), Gaps = 16/314 (5%) Query: 20 MVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRG 79 M L A LGV DL+AE G DV+ +A + S + L + L V T Sbjct: 37 MTPWALRAVVTLGVPDLVAE--GEKDVSELA---QRSGAVPDALRRVLRLLARRGVFTEP 91 Query: 80 GKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSY--RCWGHLADAVREGRNQYLETFGV 137 A + T LS L + P S L G + R H+ +A+R G + T+G Sbjct: 92 RPAVFGPTGLSR-LLQSDHPRSMRPWLDLEGPVARGDRTCVHILEALRTGGPVHERTYGR 150 Query: 138 PAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKEC 197 P E A + G A + W V FD S + D+GGG G + E Sbjct: 151 PVWEDLAA-RPALGAAFDAAMAQRASWIAG--DVAAGFDWSAVRHVMDVGGGTGGVLAEV 207 Query: 198 MSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQ-IDFQEGDFFKDPLPE-ADLYILARVLH 255 + PG K T+ D V ++ + E Q F G FF D LP AD +L VLH Sbjct: 208 LRARPGLKGTLLDRAPTVAAGREAWGASEAGQRCTFSGGSFF-DTLPSGADACLLVNVLH 266 Query: 256 DWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLN--MLVQTEGQERT 313 DWAD +L R P G +L+ E L++E GP L L+ M++ G+ER Sbjct: 267 DWADEHALAVLRRCAEAVGPRGRVLIAEHLVEEGAGGPGAAGLAELDLVMMLVYGGRERR 326 Query: 314 PTHYHMLLSSAGFR 327 L AG R Sbjct: 327 LDELADLAGKAGLR 340 >4PGH-A nrPDB Length = 358 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 86/337 (25%), Positives = 145/337 (43%), Gaps = 35/337 (10%) Query: 16 ANGFMVSQVLFAACELGVFDLLAEAPGPLDVA-------AVAAGVRASAHGTELLLDICV 68 A+ ++ L A ELG+ ++L + G A VA A+A + +L + Sbjct: 20 ASSSILPMTLKNALELGLLEVLQKDAGKALAAEEVVARLPVAPTNPAAADMVDRMLRLLA 79 Query: 69 SLKLLK--VETRGGKAFYRNTELS-SDYLTTVSPTSQCSMLKYMGRTSY--RCWGHLADA 123 S ++K +E + GK R + +LT + L M + W +L DA Sbjct: 80 SYDVVKCQMEDKDGKYERRYSAAPVGKWLTPNEDGVSMAALALMNQDKVLMESWYYLKDA 139 Query: 124 VREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSVNGRSVL---TAFDLS 178 V +G + + +G+ A E Y R F + ++ + + +L T FD S Sbjct: 140 VLDGGIPFNKAYGMTAFE-----YHGTDPRFNRVFNEGMKNHSVIITKKLLEFYTGFDES 194 Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFF 238 V L+ D+GGG GA S + + FD+P V+ A Q GD F Sbjct: 195 VSTLV-DVGGGIGATLHAITSHHSHIRGVNFDLPHVISEAPPFPGVQH------VGGDMF 247 Query: 239 KDPLPEADLYILARVLHDWADGKCSHLLERIYHTC-KPGGGILVIESLLDEDRRG-PLLT 296 K +P D ++ +LHDW+D C+ LL+ Y + GG ++V+E +L P Sbjct: 248 KS-VPAGDAILMKWILHDWSDAHCATLLKNCYDALPEKGGKVIVVECVLPVTTDAVPKAQ 306 Query: 297 QLYSLNMLVQTE---GQERTPTHYHMLLSSAGFRDFQ 330 ++ ++M++ G+ER + L +AGF F+ Sbjct: 307 GVFHVDMIMLAHNPGGRERYEREFRDLAKAAGFSGFK 343 >4EVI-A nrPDB Length = 388 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 20/166 (12%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPL 242 + D+GGG G +K +P TVFD+P VV K Q +D++ G+ F D + Sbjct: 224 LVDVGGGTGNTSKVIAETFPNIHCTVFDLPHVVSGPK-----QTHPNLDYESGNMFTDEI 278 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCKPGG--GILVI-------ESLLDEDRRGP 293 P AD + VL DW D +L++ G G L+I ES D + G Sbjct: 279 PHADAVLFKWVLCDWPDEPVLKMLKQCKKALTKNGVKGKLMIADHVLDHESCNDSNSMGT 338 Query: 294 LLTQLYSLNMLVQT--EGQERTPTHYHMLLSSAGFRDFQFKKTGAI 337 L L+ML + EG RT + L + AGF+D++ G + Sbjct: 339 SLI----LDMLFMSFLEGSLRTEKQWAKLFAEAGFKDYKITPVGGL 380 >3P9C-A nrPDB Length = 364 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 81/347 (23%), Positives = 143/347 (41%), Gaps = 39/347 (11%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPG----PLDVAA--VAAGVRAS 56 S+++ A A+ ++ L A ELG+ ++L A G P +VAA +A + Sbjct: 15 SADEDACMFALQLASSSVLPMTLKNAIELGLLEILVAAGGKSLTPTEVAAKLPSAANPEA 74 Query: 57 AHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDY--------LTTVSPTSQCSMLKY 108 + +L + S ++ GK + LS Y LT + L Sbjct: 75 PDMVDRILRLLASYNVVTCLVEEGK----DGRLSRSYGAAPVCKFLTPNEDGVSMAALAL 130 Query: 109 MG--RTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVW 164 M + W +L DAV +G + + +G+ A E Y R F + ++ Sbjct: 131 MNQDKVLMESWYYLKDAVLDGGIPFNKAYGMSAFE-----YHGTDPRFNRVFNEGMKNHS 185 Query: 165 SVNGRSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFS 223 + + +L + + D+GGG GA + YP K FD+P V+ A Q Sbjct: 186 IIITKKLLELYHGFEGLGTLVDVGGGVGATVAAIAAHYPTIKGVNFDLPHVISEAPQF-- 243 Query: 224 FQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 + GD FK+ +P D ++ +LHDW+D C+ LL+ Y G +++++ Sbjct: 244 ----PGVTHVGGDMFKE-VPSGDTILMKWILHDWSDQHCATLLKNCYDALPAHGKVVLVQ 298 Query: 284 SLLDED-RRGPLLTQLYSLNMLV---QTEGQERTPTHYHMLLSSAGF 326 +L + P ++ ++M++ G+ER + L AGF Sbjct: 299 CILPVNPEANPSSQGVFHVDMIMLAHNPGGRERYEREFQALARGAGF 345 >6I5Z-A nrPDB Length = 393 Score = 72.4 bits (176), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 46/150 (30%), Positives = 77/150 (51%), Gaps = 15/150 (10%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPL 242 + D+GGG G + ++ YP + FD+P V+ A Q+ ++ GD F++ + Sbjct: 234 LLDVGGGIGTSVSKIVAKYPLIRGVNFDLPHVISVAPQY------PGVEHVAGDMFEE-V 286 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLL------DEDRRGPLLT 296 P+ +L VLHDW D +C LL+ +++ GG +L+IE +L + + L+ Sbjct: 287 PKGQNMLLKWVLHDWGDERCVKLLKNCWNSLPVGGKVLIIEFVLPNELGNNAESFNALIP 346 Query: 297 QLYSLNMLVQTEGQERTPTHYHMLLSSAGF 326 L L M + G+ERT + Y L +AGF Sbjct: 347 DL--LLMALNPGGKERTISEYDDLGKAAGF 374 >2QYO-A nrPDB Length = 357 Score = 70.5 bits (171), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 47/158 (29%), Positives = 75/158 (47%), Gaps = 20/158 (12%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPL 242 + D+GGG G K +P VFD P+VV + + + GD F + Sbjct: 197 IVDVGGGNGTTGKIICETFPKLTCVVFDRPKVVE------NLCGSNNLTYVGGDMFIS-V 249 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCKPG-------GGILVIESLLDEDRRGPLL 295 P+AD +L VLHDW D C +L++ CK G ++VI+ +++E + L Sbjct: 250 PKADAVLLKAVLHDWTDKDCIKILKK----CKEAVTSDGKRGKVIVIDMVINEKKDENQL 305 Query: 296 TQLYSL-NMLVQ-TEGQERTPTHYHMLLSSAGFRDFQF 331 TQ+ L N+ + G+ER + L AGF+D++ Sbjct: 306 TQIKLLMNVTISCVNGKERNEEEWKKLFIEAGFQDYKI 343 >2IP2-A nrPDB Length = 334 Score = 69.7 bits (169), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 75/337 (22%), Positives = 136/337 (40%), Gaps = 34/337 (10%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 M +S A R L G S+ ++ A LG+ DL+ + A A G + A Sbjct: 1 MNNSNLAAARNLIQVVTGEWKSRCVYVATRLGLADLIESGIDSDETLAAAVG--SDAERI 58 Query: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 L+ + V+ ++ + +TR G Y NT S +L S M+ + G + W Sbjct: 59 HRLMRLLVAFEIFQGDTRDG---YANTPTS--HLLRDVEGSFRDMVLFYGEEFHAAWTPA 113 Query: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQ----------EVWSVNGRS 170 +A+ G + FG E+ ++ + R +F+ A++ + GRS Sbjct: 114 CEALLSGTPGFELAFG---EDFYSYLKRCPDAGRRFLLAMKASNLAFHEIPRLLDFRGRS 170 Query: 171 VLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFS-FQEEEQ 229 + D+GGG+G L K + P + + D + A+ + S E+ Sbjct: 171 FV------------DVGGGSGELTKAILQAEPSARGVMLDREGSLGVARDNLSSLLAGER 218 Query: 230 IDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDED 289 + GD ++ D+Y+L+R++ D + LL G ++VIE + Sbjct: 219 VSLVGGDMLQEVPSNGDIYLLSRIIGDLDEAASLRLLGNCREAMAGDGRVVVIERTISAS 278 Query: 290 RRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGF 326 P ++ L+ +++ + G+ RT LL GF Sbjct: 279 EPSP-MSVLWDVHLFMACAGRHRTTEEVVDLLGRGGF 314 >1FP2-A nrPDB Length = 352 Score = 67.8 bits (164), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 45/159 (28%), Positives = 73/159 (45%), Gaps = 22/159 (13%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPL 242 + D+GGG G AK +P K VFD P+VV + + + GD F + Sbjct: 192 IVDVGGGTGTTAKIICETFPKLKCIVFDRPQVVE------NLSGSNNLTYVGGDMFTS-I 244 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCKPG-------GGILVIESLLDEDRRGPLL 295 P AD +L +LH+W D C +L++ CK G + +I+ ++D+ + + Sbjct: 245 PNADAVLLKYILHNWTDKDCLRILKK----CKEAVTNDGKRGKVTIIDMVIDKKKDENQV 300 Query: 296 TQ---LYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQF 331 TQ L +NM G+ER + L AGF+ ++ Sbjct: 301 TQIKLLMDVNMAC-LNGKERNEEEWKKLFIEAGFQHYKI 338 >3LST-A nrPDB Length = 348 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 59/236 (25%), Positives = 102/236 (43%), Gaps = 9/236 (3%) Query: 94 LTTVSPTSQCSMLKYMGRTSYRCWGH-LADAVREGRNQYLETFGVPAEELFTAIYRSEGE 152 L + SP + + T + H +A A+ R + + FG + F +E E Sbjct: 101 LRSDSPVPARAGILMFTDTMFWTMSHRVASALGPERPAFADIFGSSLDAYFDG--DAEVE 158 Query: 153 RLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIP 212 L + + ++ V + + A D + D+GGG G + +PG + + D Sbjct: 159 AL-YYEGMETVSAAEHLILARAGDFPATGTVADVGGGRGGFLLTVLREHPGLQGVLLDRA 217 Query: 213 EVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYH 271 EVV A+ + + EGDF ++ +P AD+++L R+LH+W D +L Sbjct: 218 EVV--ARHRLDAPDVAGRWKVVEGDFLRE-VPHADVHVLKRILHNWGDEDSVRILTNCRR 274 Query: 272 TCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFR 327 G +LVI++++ E ++ ML GQERT L ++AG R Sbjct: 275 VMPAHGRVLVIDAVVPEGNDAHQSKEM-DFMMLAARTGQERTAAELEPLFTAAGLR 329 >1XDU-A nrPDB Length = 374 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 102/233 (43%), Gaps = 9/233 (3%) Query: 99 PTSQCSMLKYMGRTSYR--CWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQF 156 P Q + L G S+ + L D VR GR Y +G P E +A + + Sbjct: 103 PAQQRAWLDLNGAVSHADLAFTGLLDVVRTGRPAYAGRYGRPFWEDLSADV-ALADSFDA 161 Query: 157 MQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVW 216 + + E + + A+D S + D+GGG G + P + T+ ++ Sbjct: 162 LMSCDEDLAYEAPA--DAYDWSAVRHVLDVGGGNGGMLAAIALRAPHLRGTLVELAGPAE 219 Query: 217 TAKQHFSFQE-EEQIDFQEGDFFKDPLP-EADLYILARVLHDWADGKCSHLLERIYHTCK 274 A++ F+ +++ EGDFFK PLP AD+ +L+ VL +W+D +L + Sbjct: 220 RARRRFADAGLADRVTVAEGDFFK-PLPVTADVVLLSFVLLNWSDEDALTILRGCVRALE 278 Query: 275 PGGGILVIESL-LDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGF 326 PGG +LV++ ++ D + L L ML G+ RT L SAG Sbjct: 279 PGGRLLVLDRADVEGDGADRFFSTLLDLRMLTFMGGRVRTRDEVVDLAGSAGL 331 >1X1B-A nrPDB Length = 359 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 64/269 (23%), Positives = 122/269 (45%), Gaps = 25/269 (9%) Query: 27 AACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRN 86 AA EL +F +AE GP D+A +AA + E+LL+ ++++ +E GK + Sbjct: 50 AAIELDLFSHMAE--GPKDLATLAADTGSVPPRLEMLLETLRQMRVINLED--GK--WSL 103 Query: 87 TELSSDYLTTVSPTS----QCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEEL 142 TE + DY+ + +P Q + K M + + L+ AVR G+ + P Sbjct: 104 TEFA-DYMFSPTPKEPNLHQTPVAKAMAFLADDFYMGLSQAVR-GQKNFKGQVPYPPVTR 161 Query: 143 FTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYP 202 +Y E R A+Q +L L M D+GGG G ++ + +P Sbjct: 162 EDNLYFEEIHRSNAKFAIQ--------LLLEEAKLDGVKKMIDVGGGIGDISAAMLKHFP 213 Query: 203 GCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEG---DFFKDPLPEADLYILARVLHDWAD 259 T+ ++P + ++ + E+ D G D +K+ PEAD + R+L+ + Sbjct: 214 ELDSTILNLPGAIDLVNENAA--EKGVADRMRGIAVDIYKESYPEADAVLFCRILYSANE 271 Query: 260 GKCSHLLERIYHTCKPGGGILVIESLLDE 288 + + ++ + + GG +L+++ ++D+ Sbjct: 272 QLSTIMCKKAFDAMRSGGRLLILDMVIDD 300 >4WXH-A nrPDB Length = 367 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 65/214 (30%), Positives = 94/214 (43%), Gaps = 7/214 (3%) Query: 116 CWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAF 175 + L DA+R GR Y +G P + + R F L V + A+ Sbjct: 129 SFTRLPDAIRTGRPTYESIYGKP---FYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAY 185 Query: 176 DLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQE 234 D + + D+GGG G A P TV ++ V TA+ + + +++D E Sbjct: 186 DWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVE 245 Query: 235 GDFFKDPLP-EADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE-SLLDEDRRG 292 GDFF+ PLP +AD IL+ VL +W D +L R +PGG IL+ E L E+ Sbjct: 246 GDFFE-PLPRKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFN 304 Query: 293 PLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGF 326 + L MLV G RT + L +SAG Sbjct: 305 EQFSTELDLRMLVFLGGALRTREKWDGLAASAGL 338 >3MCZ-A nrPDB Length = 352 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 79/324 (24%), Positives = 135/324 (41%), Gaps = 30/324 (9%) Query: 3 SSEDQAYRL----LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAH 58 S+ED+A L ++ + S +L A +FDL P +VAA V A Sbjct: 15 STEDKAALTSVVDLVKLSDQYRQSAILHYAVADKLFDLTQTGRTPAEVAASFGMVEGKA- 73 Query: 59 GTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWG 118 + +L L + T+ G AF RNT L+ YLTT S ++++ + W Sbjct: 74 -----AILLHALAALGLLTKEGDAF-RNTALTERYLTTTSADYIGPIVEHQ-YLQWDNWP 126 Query: 119 HLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLS 178 L + +R + E F R+ R F A+ + + V +L Sbjct: 127 RLGEILRSEK-----PLAFQQESRFAHDTRA---RDAFNDAMVRL---SQPMVDVVSELG 175 Query: 179 VFP---LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQE 234 VF + DL GG G + + +P ++D+P A++ + +++F E Sbjct: 176 VFARARTVIDLAGGHGTYLAQVLRRHPQLTGQIWDLPTTRDAARKTIHAHDLGGRVEFFE 235 Query: 235 GDFFKDPLPE---ADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRR 291 + E AD+ +L LH + + ++ KPGG +L++ +++DR Sbjct: 236 KNLLDARNFEGGAADVVMLNDCLHYFDAREAREVIGHAAGLVKPGGALLILTMTMNDDRV 295 Query: 292 GPLLTQLYSLNMLVQTEGQERTPT 315 P L+ +SL+M+V T E PT Sbjct: 296 TPALSADFSLHMMVNTNHGELHPT 319 >3I64-A nrPDB Length = 332 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 6/93 (6%) Query: 235 GDFFKDPLPE-ADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGP 293 G FF DPLP A Y+L+ VLHDW D +L R GG +LVIE++ ++ G Sbjct: 226 GSFF-DPLPAGAGGYVLSAVLHDWDDLSAVAILRRCAEAAGSGGVVLVIEAVAGDEHAGT 284 Query: 294 LLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGF 326 + L ML G+ER+ L + AG Sbjct: 285 GM----DLRMLTYFGGKERSLAELGELAAQAGL 313 >5W7R-A nrPDB Length = 429 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 77/326 (23%), Positives = 126/326 (38%), Gaps = 45/326 (13%) Query: 51 AGVRASAHGTELLLDICVSLKLLKVET------RGGKAFYRNTELSSDYLTTVSPTSQCS 104 A + AS + LD + ++L++ T G+ Y +T S YLT Sbjct: 115 ASMTASEISAQTGLDKGILIRLMRAVTPLGPFHEVGEEEYAHTPFSEAYLTADIAGCFPV 174 Query: 105 MLKYM-GRTSYRC----WGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQA 159 M ++ G C + DA+ N + P E +F +Y++ +A Sbjct: 175 MSNFIFGPVLQICDFLRQNNWKDAITTRNNPFTLAHNCPGETMFEHLYKNSKNVAPVTKA 234 Query: 160 LQEVWSVNGRSVLTAFDLSVFP-------------LMCDLGGGAGALAKECMSLYP---G 203 E V+ A DL +P + D+ G G + M+L P G Sbjct: 235 --EAADVDQ----IAMDL--YPWEERLSDAKGSNATLVDIAGSHGNGTRAIMALAPKLNG 286 Query: 204 CKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD--PLPEADLYILARVLHDWAD-G 260 C+ V D+ V+ +H E I+ Q DF K P+ A +Y RV HDW D Sbjct: 287 CRFIVQDLEPVI---GEHSQALRAEGIEPQVYDFLKQEQPVHGASIYYFRRVFHDWPDLP 343 Query: 261 KCSHLLERIYHT-CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHM 319 + +L+ + IL+ + ++ E G ++ + L+ G ERT + Sbjct: 344 EGKKILDNTRAAMSREHSRILIHDIIVPE--IGATMSHAWQDLSLMAIGGMERTEKDFAR 401 Query: 320 LLSSAGFRDFQ-FKKTGAIYDAILAR 344 LL AG + ++K G + I AR Sbjct: 402 LLDIAGLALVKVWRKPGDMMGIIEAR 427 >3DP7-A nrPDB Length = 363 Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 58/297 (19%), Positives = 122/297 (41%), Gaps = 29/297 (9%) Query: 7 QAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDI 66 +A RL + A G +V QV + G+F LL+ + ++ + + ++LL+ Sbjct: 14 EAQRLAQEIAFGPVVFQVSRLMLKFGIFQLLSGKREGYTLQEISGRTGLTRYAAQVLLEA 73 Query: 67 CVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVRE 126 +++ + +E L +D + V+ +++ +Y+ HL +A+ Sbjct: 74 SLTIGTILLEEDRYVLAKAGWFLLNDKMARVN-------MEFNHDVNYQGLFHLEEALLN 126 Query: 127 GRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVW---------SVNGRSVLTAFDL 177 GR + L+ FG + IY Q + +Q+ W G+++ F Sbjct: 127 GRPEGLKVFGE-----WPTIYEGLS---QLPEQVQKSWFGFDHFYSDQSFGKALEIVFSH 178 Query: 178 SVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVV-WTAKQHFSFQEEEQIDFQEGD 236 L+ D+GG G A +C+ ++T+ D+P+ + KQ E+I + Sbjct: 179 HPKRLL-DIGGNTGKWATQCVQYNKEVEVTIVDLPQQLEMMRKQTAGLSGSERIHGHGAN 237 Query: 237 FFKD--PLPEA-DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDR 290 P P D +++ L +++ + +L R+ + + ++E+L D R Sbjct: 238 LLDRDVPFPTGFDAVWMSQFLDCFSEEEVISILTRVAQSIGKDSKVYIMETLWDRQR 294 >2R3S-A nrPDB Length = 335 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 77/334 (23%), Positives = 128/334 (38%), Gaps = 35/334 (10%) Query: 11 LLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 L + N + S + AA EL VF +++ G ++A + S G +L D V + Sbjct: 9 LFFNTVNAYQRSAAIKAAVELNVFTAISQ--GIESSQSLAQKCQTSERGMRMLCDYLVII 66 Query: 71 KLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYM-GRTSYRCWGHLADAVREGRN 129 + + G YR T S+ +L S ++++ + L AV +G Sbjct: 67 GFMTKQAEG----YRLTSDSAMFLDRQSKFYVGDAIEFLLSPMITNGFNDLTAAVLKGG- 121 Query: 130 QYLETFGVPAEELFTAIYRSEGER-------LQFMQALQEVWSVNGRSVLTAFDLS-VFP 181 TAI SEG +QF +A+ + + + + + + + P Sbjct: 122 --------------TAI-SSEGTLSPEHPVWVQFAKAMSPMMANPAQLIAQLVNENKIEP 166 Query: 182 L-MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQ-EEEQIDFQEGDFFK 239 L + D+ G P +I D V+ AK++ Q + G F+ Sbjct: 167 LKVLDISASHGLFGIAVAQHNPNAEIFGVDWASVLEVAKENARIQGVASRYHTIAGSAFE 226 Query: 240 -DPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQL 298 D + DL +L LH + C LL +I G ++V + + + DR P Sbjct: 227 VDYGNDYDLVLLPNFLHHFDVATCEQLLRKIKTALAVEGKVIVFDFIPNSDRITPPDAAA 286 Query: 299 YSLNMLVQT-EGQERTPTHYHMLLSSAGFRDFQF 331 +SL ML T G T Y + S+AGF Q Sbjct: 287 FSLVMLATTPNGDAYTFAEYESMFSNAGFSHSQL 320 >4GEK-A nrPDB Length = 261 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 5/124 (4%) Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFD-IPEVVWTAKQHF-SFQEEEQIDFQEGD 236 V+ L C LG ++ + + CKI D P ++ ++H +++ +D EGD Sbjct: 74 VYDLGCSLGAATLSVRRNIH--HDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGD 131 Query: 237 FFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRR-GPLL 295 + A + +L L + LL++IY PGG +++ E ED + G LL Sbjct: 132 IRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELL 191 Query: 296 TQLY 299 ++ Sbjct: 192 FNMH 195 >4IWN-A nrPDB Length = 229 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 55/124 (44%), Gaps = 5/124 (4%) Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFD-IPEVVWTAKQHF-SFQEEEQIDFQEGD 236 V+ L C LG ++ + + CKI D P ++ + H +++ +D EGD Sbjct: 42 VYDLGCSLGAATLSVRRNIH--HDNCKIIAIDNSPAMIERCRHHIDAYKAPTPVDVIEGD 99 Query: 237 FFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRR-GPLL 295 + A + +L L + LL++IY PGG +++ E ED + G LL Sbjct: 100 IRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELL 159 Query: 296 TQLY 299 ++ Sbjct: 160 FNMH 163 >4MWZ-A nrPDB Length = 267 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 8/123 (6%) Query: 170 SVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQ 229 +L+ L + D+G G G K Y G + DI E + T + Q++ + Sbjct: 46 KILSDIQLDANSKVLDIGSGLGGGCKYINEKY-GAHVHGVDICEKMVTIAK-LRNQDKAK 103 Query: 230 IDFQEGDFFKDPLPEAD---LYILARVLH-DWADGKCSHLLERIYHTCKPGGGILVIESL 285 I+F+ D K PE+ +Y +LH +AD K L E+ Y KP G +L+ + Sbjct: 104 IEFEAKDILKKDFPESTFDMIYSRDSILHLSYADKKM--LFEKCYKWLKPNGILLITDYC 161 Query: 286 LDE 288 D+ Sbjct: 162 ADK 164 >5F8E-A nrPDB Length = 377 Score = 35.8 bits (81), Expect = 0.030, Method: Compositional matrix adjust. Identities = 30/128 (23%), Positives = 58/128 (45%), Gaps = 8/128 (6%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQEEEQIDFQEGDFFK-D 240 + D G G+G K + + T D E V + + F+ D + D Sbjct: 191 VADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLAELD 250 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE----SLLDEDRRGPLLT 296 + D+ + +HD A + + +L+ IY +PGG +L+++ S L+++ PL T Sbjct: 251 KVGAYDVITVFDAIHDQA--QPARVLQNIYRALRPGGVLLMVDIKASSQLEDNVGVPLST 308 Query: 297 QLYSLNML 304 LY+ +++ Sbjct: 309 YLYTTSLM 316 >2B3T-A nrPDB Length = 276 Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 17/109 (15%) Query: 148 RSEGERLQFMQALQEVWS----VNGRSVLTAFD--------LSVFP----LMCDLGGGAG 191 R +GE + + ++E WS V+ +++ D L+ P + DLG G G Sbjct: 62 RRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQALARLPEQPCRILDLGTGTG 121 Query: 192 ALAKECMSLYPGCKITVFD-IPEVVWTAKQHFSFQEEEQIDFQEGDFFK 239 A+A S P C+I D +P+ V A+++ + I + D+F Sbjct: 122 AIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKNIHILQSDWFS 170 >1IXC-A nrPDB Length = 294 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 22/128 (17%) Query: 80 GKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREG------RNQYLE 133 G YR+ L T +PT+ S L +M + + G LA + G R+ +E Sbjct: 99 GTPIYRSLPLLLRAFLTSTPTATVS-LTHMTKDE-QVEGLLAGTIHVGFSRFFPRHPGIE 156 Query: 134 TFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGAL 193 + E+L+ A++RS+ + L + L A +L++FP GG + Sbjct: 157 IVNIAQEDLYLAVHRSQSGKFGKTCKLAD---------LRAVELTLFPR-----GGRPSF 202 Query: 194 AKECMSLY 201 A E + L+ Sbjct: 203 ADEVIGLF 210 >5GM1-A nrPDB Length = 297 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 24/88 (27%), Positives = 37/88 (42%), Gaps = 15/88 (17%) Query: 257 WADGKCSHL-----LERIYHTCKPGGGILVIESLLDEDRRGP---LLTQLYSLNMLVQTE 308 WA H+ L + KPGG +LV+ES++ E+ P L LY+ N+ + Sbjct: 150 WAIESLCHMDRAKALGEAWRVLKPGGDLLVLESVVTEELTEPETALFETLYAANVPPRL- 208 Query: 309 GQERTPTHYHMLLSSAGFRDFQFKKTGA 336 + ++S AGF K A Sbjct: 209 ------GEFFDIVSGAGFHTLSLKDLSA 230 >6DCC-A nrPDB Length = 309 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 5/52 (9%) Query: 236 DFFKDPLPEADLYI---LARVLH-DWADGKCSHLLERIYHTCKPGGGILVIE 283 D + PE D+ + L + +H +W D + RIY +P GGILV+E Sbjct: 186 DLVEAQTPEYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRP-GGILVLE 236 >3L8C-A nrPDB Length = 521 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 4/53 (7%) Query: 174 AFDLSVF---PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFS 223 +FDLSV P + LGG AL KE ++ + T+ +P +WT+ F+ Sbjct: 198 SFDLSVMYWAPTLA-LGGTLFALPKELVADFKQLFTTIAQLPVGIWTSTPSFA 249 >1I5N-A nrPDB Length = 146 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 16/90 (17%) Query: 235 GDFFKDPLPEADLYI------LARVLHDWADGKCSHLLERIYHTCKPGGGIL-------- 280 DF++ EAD + L ++ + D + + + R H+ K G G Sbjct: 6 SDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQET 65 Query: 281 --VIESLLDEDRRGPLLTQLYSLNMLVQTE 308 ++E+LLDE RRG + +N+ ++T+ Sbjct: 66 THLMENLLDEARRGEMQLNTDIINLFLETK 95 >2AXR-A nrPDB Length = 503 Score = 28.1 bits (61), Expect = 5.4, Method: Compositional matrix adjust. Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 26/138 (18%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVV--------WTAKQHFSFQEEEQIDFQ 233 L L GG G A + + F+ PE++ W KQH + + Q Sbjct: 187 LFWALRGGGGGFA-----IVSEFEFNTFEAPEIITTYQVTTTWNRKQHVAGLKALQ---- 237 Query: 234 EGDFFKDPLPEA---DLYILARVLHDWAD---GKCSHLLERIYHTCKPGGGILVIESLLD 287 D+ ++ +P L I A L +W G L + + K GG I L++ Sbjct: 238 --DWAQNTMPRELSMRLEINANAL-NWEGNFFGNAKDLKKILQPIMKKAGGKSTISKLVE 294 Query: 288 EDRRGPLLTQLYSLNMLV 305 D G + T LY ++ + Sbjct: 295 TDWYGQINTYLYGADLNI 312 >2LP4-A nrPDB Length = 225 Score = 28.1 bits (61), Expect = 6.2, Method: Compositional matrix adjust. Identities = 22/90 (24%), Positives = 41/90 (45%), Gaps = 16/90 (17%) Query: 235 GDFFKDPLPEADLYI------LARVLHDWADGKCSHLLERIYHTCKPGGGIL-------- 280 DF++ EAD + L ++ + D + + + R H+ K G G Sbjct: 6 SDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIFRAAHSIKGGAGTFGFTILQET 65 Query: 281 --VIESLLDEDRRGPLLTQLYSLNMLVQTE 308 ++E+LLDE RRG + +N+ ++T+ Sbjct: 66 THLMENLLDEARRGEMQLNTDIINLFLETK 95 >5GZA-A nrPDB Length = 290 Score = 27.7 bits (60), Expect = 6.8, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 8/68 (11%) Query: 209 FDIPEVVWTAKQHFSFQEEEQIDFQEG-DFFKDPLPEADLYILARVLHDWADGKCSHL-L 266 F PE +W + FSF +E + E D +K +P+ ++L VL G H L Sbjct: 198 FVAPEQLWPYGEDFSFSDEAMPGYDEKTDIWK--IPDVTRFLLGDVL----GGDVIHFHL 251 Query: 267 ERIYHTCK 274 +IY CK Sbjct: 252 FQIYSECK 259 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4A6D-A nrPDB 421 e-118 6IWT-A nrPDB 314 3e-86 1KYW-A nrPDB 311 2e-85 5CVU-A nrPDB 302 2e-82 3P9C-A nrPDB 301 3e-82 6C5B-A nrPDB 295 2e-80 5ICG-A nrPDB 291 3e-79 4PGH-A nrPDB 290 5e-79 5XOH-A nrPDB 290 8e-79 1FP1-D nrPDB 265 1e-71 4Z2Y-A nrPDB 263 1e-70 2IP2-A nrPDB 251 4e-67 1ZG3-A nrPDB 250 1e-66 1FP2-A nrPDB 247 4e-66 5I2H-A nrPDB 242 1e-64 4D7K-A nrPDB 242 2e-64 3GXO-A nrPDB 240 5e-64 2QYO-A nrPDB 236 1e-62 4EVI-A nrPDB 232 3e-61 6CLW-A nrPDB 231 3e-61 2R3S-A nrPDB 229 1e-60 4X3Q-A nrPDB 221 4e-58 6I5Z-A nrPDB 216 1e-56 1XDU-A nrPDB 213 7e-56 3MCZ-A nrPDB 213 8e-56 5W7R-A nrPDB 205 2e-53 4WXH-A nrPDB 200 8e-52 3LST-A nrPDB 198 2e-51 1X1B-A nrPDB 196 9e-51 3DP7-A nrPDB 193 9e-50 3I64-A nrPDB 159 2e-39 Sequences not found previously or not previously below threshold: 6J1O-A nrPDB 116 2e-26 4KIC-A nrPDB 79 3e-15 2GLU-A nrPDB 61 6e-10 4IV8-A nrPDB 61 8e-10 3MGG-A nrPDB 60 2e-09 4MWZ-A nrPDB 58 5e-09 4INE-A nrPDB 56 3e-08 5F8E-A nrPDB 54 1e-07 3BUS-A nrPDB 53 1e-07 2PJD-A nrPDB 53 2e-07 5GM1-A nrPDB 52 4e-07 5E2B-A nrPDB 51 7e-07 1XTP-A nrPDB 51 9e-07 4FGZ-A nrPDB 50 1e-06 4KRI-A nrPDB 48 4e-06 4KRG-A nrPDB 48 7e-06 5UBB-A nrPDB 48 8e-06 5WP5-A nrPDB 47 2e-05 2O57-A nrPDB 46 3e-05 4FS8-A nrPDB 46 3e-05 5MGZ-A nrPDB 45 4e-05 5WP4-A nrPDB 44 6e-05 3D2L-A nrPDB 44 8e-05 5M58-A nrPDB 44 8e-05 5JE5-A nrPDB 44 9e-05 3I9F-A nrPDB 43 2e-04 6MRO-A nrPDB 43 2e-04 2B3T-A nrPDB 42 3e-04 5BXY-A nrPDB 42 3e-04 4DCM-A nrPDB 42 3e-04 3CCF-A nrPDB 42 3e-04 1JG3-A nrPDB 42 3e-04 1L3B-A nrPDB 42 4e-04 3OU6-A nrPDB 41 6e-04 6QMM-B nrPDB 41 7e-04 5BSZ-A nrPDB 41 7e-04 6DCC-A nrPDB 40 0.002 4HTF-A nrPDB 39 0.003 3HNR-A nrPDB 39 0.003 5U19-A nrPDB 39 0.003 3R9X-B nrPDB 39 0.004 4PNE-A nrPDB 38 0.006 6F5Z-A nrPDB 38 0.007 3HM2-A nrPDB 37 0.011 1XDZ-A nrPDB 36 0.025 1N2X-A nrPDB 36 0.037 4YUX-A nrPDB 35 0.046 5EGS-A nrPDB 35 0.051 2FCA-A nrPDB 35 0.052 1ZQ9-A nrPDB 35 0.058 5MMS-A nrPDB 34 0.074 4COO-A nrPDB 34 0.074 1M54-A nrPDB 34 0.074 2AVN-A nrPDB 34 0.077 5WMM-A nrPDB 34 0.079 4KDR-A nrPDB 34 0.086 4KDC-A nrPDB 34 0.086 5LV5-A nrPDB 34 0.092 5H02-A nrPDB 34 0.099 4OBX-A nrPDB 34 0.11 2O06-A nrPDB 34 0.11 3E23-A nrPDB 34 0.12 5BP7-A nrPDB 34 0.14 5Y4R-A nrPDB 33 0.16 1VQ1-A nrPDB 33 0.19 3VRD-B nrPDB 33 0.20 3SM3-A nrPDB 33 0.21 4DZR-A nrPDB 33 0.21 2GS9-A nrPDB 32 0.25 1DL5-A nrPDB 32 0.26 1INL-A nrPDB 32 0.27 3HA5-A nrPDB 32 0.28 5GJN-A nrPDB 32 0.45 2HUN-A nrPDB 32 0.48 3O4F-A nrPDB 31 0.58 1XJ5-A nrPDB 31 0.58 4QPN-A nrPDB 31 0.70 2VDV-E nrPDB 31 0.76 1YZH-A nrPDB 31 0.93 1UIR-A nrPDB 31 1.0 5N1T-A nrPDB 30 1.3 4FWE-A nrPDB 30 1.3 6GKZ-A nrPDB 30 1.4 4RX1-A nrPDB 30 1.4 3CJR-A nrPDB 30 1.5 2YXD-A nrPDB 30 1.5 6GDG-A nrPDB 30 1.8 2O3J-A nrPDB 30 1.9 3TMA-A nrPDB 29 3.3 5KPG-A nrPDB 29 3.4 4JXJ-A nrPDB 29 3.4 4OKY-C nrPDB 29 4.3 3MQ2-A nrPDB 28 4.9 3UI2-A nrPDB 28 7.0 >4A6D-A nrPDB Length = 353 Score = 421 bits (1081), Expect = e-118, Method: Composition-based stats. Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT Sbjct: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 Query: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL Sbjct: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 Query: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF Sbjct: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180 Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD 240 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD Sbjct: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD 240 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS 300 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS Sbjct: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS 300 Query: 301 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK Sbjct: 301 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 >6IWT-A nrPDB Length = 364 Score = 314 bits (804), Expect = 3e-86, Method: Composition-based stats. Identities = 85/346 (24%), Positives = 143/346 (41%), Gaps = 31/346 (8%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPL--DVAAVAAGVRASAHGTE 61 E++A A+ ++ VL +A EL + + +A+A + +AA + +S T Sbjct: 16 EEEEACMFAMQLASASVLPMVLKSAIELDLLESIAKAGPGAYVSPSELAAKLPSSQPDTP 75 Query: 62 LLL----DICVSLKLLKVETR----GGKAFYRNTELSSDYLTTVSPTSQCSMLKYM--GR 111 ++L + S +LK + + GG +LT S + L M + Sbjct: 76 VMLDRILRLLASYSVLKCKVQDLPQGGVERLYALAPVCKFLTKNSDGVSMAPLLLMNQDK 135 Query: 112 TSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSVNGR 169 W HL DAV +G + + +G+ A E Y + R F + ++ + Sbjct: 136 ILMESWYHLKDAVLDGGIPFNKAYGMTAFE-----YHGKDPRFNKVFNLGMSNHSTITMK 190 Query: 170 SVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE 228 +L ++ + + D+GGG GA +S YP K FD+P VV A + Sbjct: 191 KILQTYNGFAGLKTVVDVGGGTGATLNMIISKYPNIKGINFDLPHVVEDAPSY------P 244 Query: 229 QIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE 288 ++ GD F +PE D + + HDW+D C L+ Y G +++ E +L E Sbjct: 245 GVEHVGGDMFVS-VPEGDAIFMKWICHDWSDAHCLSFLKNCYKALPQNGKVILAECILPE 303 Query: 289 DRRGPLLTQLY---SLNMLV-QTEGQERTPTHYHMLLSSAGFRDFQ 330 L T+ + ML G+ERT + L AGF+ F Sbjct: 304 APDSKLTTKNVIHIDVIMLAHNPGGKERTEKEFEALGKMAGFKSFN 349 >1KYW-A nrPDB Length = 365 Score = 311 bits (797), Expect = 2e-85, Method: Composition-based stats. Identities = 79/348 (22%), Positives = 146/348 (41%), Gaps = 31/348 (8%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGP--LDVAAVAAGVRASAHGTE 61 S+++A A+ ++ +L +A EL + +++A+A + +A+ + + Sbjct: 15 SDEEANLFAMQLASASVLPMILKSALELDLLEIIAKAGPGAQISPIEIASQLPTTNPDAP 74 Query: 62 LLLD------ICVSLKLLKVETRGGKAFYRNTELS--SDYLTTVSPTSQCSMLKYM--GR 111 ++LD C + V T+ R L+ + YL S L M + Sbjct: 75 VMLDRMLRLLACYIILTCSVRTQQDGKVQRLYGLATVAKYLVKNEDGVSISALNLMNQDK 134 Query: 112 TSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSVNGR 169 W HL DAV +G + + +G+ A E Y R F + + + ++ + Sbjct: 135 VLMESWYHLKDAVLDGGIPFNKAYGMTAFE-----YHGTDPRFNKVFNKGMSDHSTITMK 189 Query: 170 SVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE 228 +L + + D+GGG GA+ +S YP K FD+P V+ A + Sbjct: 190 KILETYTGFEGLKSLVDVGGGTGAVINTIVSKYPTIKGINFDLPHVIEDAPSY------P 243 Query: 229 QIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE 288 ++ GD F +P+AD + + HDW+D C L+ Y G ++V E +L Sbjct: 244 GVEHVGGDMFVS-IPKADAVFMKWICHDWSDEHCLKFLKNCYEALPDNGKVIVAECILPV 302 Query: 289 DRRGPLLTQ-LYSLNMLV---QTEGQERTPTHYHMLLSSAGFRDFQFK 332 L T+ + +++++ G+ERT + L AGF+ F+ Sbjct: 303 APDSSLATKGVVHIDVIMLAHNPGGKERTQKEFEDLAKGAGFQGFKVH 350 >5CVU-A nrPDB Length = 368 Score = 302 bits (773), Expect = 2e-82, Method: Composition-based stats. Identities = 77/347 (22%), Positives = 143/347 (41%), Gaps = 28/347 (8%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGP---LDVAAVAAGVRASAHG 59 SS+++A A+ ++ L AA EL V +++A++ P + A +AA + + Sbjct: 16 SSDEEANLFAMQLASAAVLPMALKAAIELDVLEIMAKSVPPSGYISPAEIAAQLPTTNPE 75 Query: 60 TELLL-DICVSLKLLKVET-------RGGKAFYRNTELSSDYLTTVSPTSQCS--MLKYM 109 ++L + L V T G +LT + +L Sbjct: 76 APVMLDRVLRLLASYSVVTYTLRELPSGKVERLYGLAPVCKFLTKNEDGVSLAPFLLLAT 135 Query: 110 GRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGR 169 + W +L DA+ EG + + +G+ + F +R F + + ++ + Sbjct: 136 DKVLLEPWFYLKDAILEGGIPFNKAYGMNIWDYFGTDHRINK---VFNKGMSSNSTITMK 192 Query: 170 SVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE 228 +L ++ + D+GGG GA+A ++ YP FD+P V+ A Sbjct: 193 KILEMYNGFEGLTTIVDVGGGTGAVASMIVAKYPSINAINFDLPHVIQDAPAF------S 246 Query: 229 QIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE 288 ++ GD F D +P+ D + + HDW+D C LL+ Y G ++V E +L Sbjct: 247 GVEHLGGDMF-DGVPKGDAIFIKWICHDWSDEHCLKLLKNCYAALPDHGKVIVAEYILPP 305 Query: 289 DRRGPLLTQLY----SLNMLVQTEGQERTPTHYHMLLSSAGFRDFQF 331 + T++ +L + G+ERT + L ++GFR F+ Sbjct: 306 SPDPSIATKVVIHTDALMLAYNPGGKERTEKEFQALAMASGFRGFKV 352 >3P9C-A nrPDB Length = 364 Score = 301 bits (771), Expect = 3e-82, Method: Composition-based stats. Identities = 80/362 (22%), Positives = 143/362 (39%), Gaps = 31/362 (8%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLL-AEAPGPLDVAAVAAGVRAS----- 56 S+++ A A+ ++ L A ELG+ ++L A L VAA + ++ Sbjct: 15 SADEDACMFALQLASSSVLPMTLKNAIELGLLEILVAAGGKSLTPTEVAAKLPSAANPEA 74 Query: 57 AHGTELLLDICVSLKLLKVETRGGKA----FYRNTELSSDYLTTVSPTSQCSMLKYM--G 110 + +L + S ++ GK +LT + L M Sbjct: 75 PDMVDRILRLLASYNVVTCLVEEGKDGRLSRSYGAAPVCKFLTPNEDGVSMAALALMNQD 134 Query: 111 RTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSVNG 168 + W +L DAV +G + + +G+ A E Y R F + ++ + Sbjct: 135 KVLMESWYYLKDAVLDGGIPFNKAYGMSAFE-----YHGTDPRFNRVFNEGMKNHSIIIT 189 Query: 169 RSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEE 227 + +L + + D+GGG GA + YP K FD+P V+ A Q Sbjct: 190 KKLLELYHGFEGLGTLVDVGGGVGATVAAIAAHYPTIKGVNFDLPHVISEAPQF------ 243 Query: 228 EQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLD 287 + GD FK+ +P D ++ +LHDW+D C+ LL+ Y G +++++ +L Sbjct: 244 PGVTHVGGDMFKE-VPSGDTILMKWILHDWSDQHCATLLKNCYDALPAHGKVVLVQCILP 302 Query: 288 EDRR-GPLLTQLYSLNMLV---QTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILA 343 + P ++ ++M++ G+ER + L AGF + A AI Sbjct: 303 VNPEANPSSQGVFHVDMIMLAHNPGGRERYEREFQALARGAGFTGVKSTYIYANAWAIEF 362 Query: 344 RK 345 K Sbjct: 363 TK 364 >6C5B-A nrPDB Length = 341 Score = 295 bits (754), Expect = 2e-80, Method: Composition-based stats. Identities = 88/335 (26%), Positives = 147/335 (43%), Gaps = 11/335 (3%) Query: 11 LLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 +L G+ V+Q L+ A +LG+ DL+A+AP P++ +AA A A LL + ++ Sbjct: 15 ILLQMITGYWVTQSLYVAAKLGIADLVADAPKPIE--ELAAKTGAKAP---LLKRVLRTI 69 Query: 71 KLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQ 130 + V T + T L++ L + +P S G YR W + V+ G Sbjct: 70 ASIGVFTETEPGIFGITPLAA-LLRSGTPDSMRPQAIMHGEEQYRAWADVLHNVQTGETA 128 Query: 131 YLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGA 190 + + FG F + + F +A +V+ A+D S F + D+G G Sbjct: 129 FEKEFGT---SYFGYLAKHPEADRVFNEAQAGYTKQVAHAVVDAYDFSPFKTVIDIGAGY 185 Query: 191 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEADLYI 249 G L + P + +FD P V A + + ++ GDFF + + D+YI Sbjct: 186 GPLLSAILRSQPEARGILFDQPHVAQAAGKRLAEAGVGDRCGTVGGDFFVEVPADGDVYI 245 Query: 250 LARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEG 309 L+ +LHDW D + +L G +L++E +L E P + L+MLV Sbjct: 246 LSLLLHDWDDQRSIEILRNCRRAMPAHGKLLIVELVLPEGEE-PFFGKWLDLHMLVLLGA 304 Query: 310 QERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILAR 344 QERT + L +++GF + T + + AR Sbjct: 305 QERTADEFKTLFAASGFALERVLPTASGLSIVEAR 339 >5ICG-A nrPDB Length = 352 Score = 291 bits (745), Expect = 3e-79, Method: Composition-based stats. Identities = 69/355 (19%), Positives = 145/355 (40%), Gaps = 23/355 (6%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 + + L ++ GF S VL +A +L + +++ P+ ++ ++ + + Sbjct: 6 INKENLSSQAKLWNFIYGFADSLVLKSAVQLDLANIIHNHGSPMTLSELSLHLPSQPVNQ 65 Query: 61 ELL---LDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQ-CSMLKYMGRTSYRC 116 + L L V +KL + G+ Y + +L ++L + Sbjct: 66 DALYRVLRYLVHMKLFTKSSIDGELRYGLAP-PAKFLVKGWDKCMLGAILTITDKDFMAP 124 Query: 117 WGHLADAVREGR---NQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLT 173 W +L + + + + G ++ + + F + + + +++ Sbjct: 125 WHYLKEGILNDGSTSTAFEKALGT---NIWDYMAEHPEKNQLFNEGMANDTRLIMSALVK 181 Query: 174 AFD--LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQID 231 + D+GGG G + +P K TV+D+P V+ + +I+ Sbjct: 182 ECSSMFDGITTIVDVGGGTGTAVRNIAKAFPHIKCTVYDLPHVIADSP------GYTEIN 235 Query: 232 FQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCK-PGGGILVIESLLDEDR 290 +GD FK +P AD ++ +LHDW D +C +L+R GG +++I+ +LD Sbjct: 236 SIQGDMFK-YIPNADAIMMKCILHDWDDKECIEILKRCKDAVPRDGGKVIIIDIILDVKS 294 Query: 291 RGPL--LTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILA 343 P + L+M++ T G+ERT + L+ AG++ ++ A+ I A Sbjct: 295 EHPYTKMRLTLDLDMMLNTGGKERTEEEWKKLIHDAGYKGYKITHISAVQSVIEA 349 >4PGH-A nrPDB Length = 358 Score = 290 bits (742), Expect = 5e-79, Method: Composition-based stats. Identities = 80/360 (22%), Positives = 143/360 (39%), Gaps = 33/360 (9%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAA-------VAAGVRAS 56 ++++A A+ ++ L A ELG+ ++L + G A VA A+ Sbjct: 8 ADEEACMYAMQLASSSILPMTLKNALELGLLEVLQKDAGKALAAEEVVARLPVAPTNPAA 67 Query: 57 AHGTELLLDICVSLKLLKVETRGGKAFY---RNTELSSDYLTTVSPTSQCSMLKYM--GR 111 A + +L + S ++K + Y + +LT + L M + Sbjct: 68 ADMVDRMLRLLASYDVVKCQMEDKDGKYERRYSAAPVGKWLTPNEDGVSMAALALMNQDK 127 Query: 112 TSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQ--FMQALQEVWSVNGR 169 W +L DAV +G + + +G+ A E Y R F + ++ + + Sbjct: 128 VLMESWYYLKDAVLDGGIPFNKAYGMTAFE-----YHGTDPRFNRVFNEGMKNHSVIITK 182 Query: 170 SVLTAFDL--SVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEE 227 +L + + D+GGG GA S + + FD+P V+ A Sbjct: 183 KLLEFYTGFDESVSTLVDVGGGIGATLHAITSHHSHIRGVNFDLPHVISEAPPF------ 236 Query: 228 EQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKP-GGGILVIESLL 286 + GD FK +P D ++ +LHDW+D C+ LL+ Y GG ++V+E +L Sbjct: 237 PGVQHVGGDMFKS-VPAGDAILMKWILHDWSDAHCATLLKNCYDALPEKGGKVIVVECVL 295 Query: 287 DEDRRG-PLLTQLYSLNMLV---QTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAIL 342 P ++ ++M++ G+ER + L +AGF F+ A AI Sbjct: 296 PVTTDAVPKAQGVFHVDMIMLAHNPGGRERYEREFRDLAKAAGFSGFKATYIYANAWAIE 355 >5XOH-A nrPDB Length = 359 Score = 290 bits (741), Expect = 8e-79, Method: Composition-based stats. Identities = 71/346 (20%), Positives = 146/346 (42%), Gaps = 28/346 (8%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGP--LDVAAVAAGVRASAHGT 60 S +++A L A ++ +L +A EL + + +++A L + +A+ + S Sbjct: 9 SQDEEACVLAIQLATSTVLPMILKSAIELDILNTISKAGPGNYLSPSDLASKLLMSNPHA 68 Query: 61 ELLL----DICVSLKLLKV----ETRGGKAFYRNTELSSDYLTTVSPTSQCS--MLKYMG 110 ++L + + K+L + G + +L+ + + +L + Sbjct: 69 PIMLERILRVLATYKVLGCKPSELSDGEVEWLYCWTPVCKFLSNNEDGASIAPLLLVHQD 128 Query: 111 RTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRS 170 + + W HL DA+ +G + + +G+ +F + F +++ ++ + Sbjct: 129 QVPMKSWYHLTDAILDGGTAFNKAYGM---NIFDYASQDPQFNKVFNRSMAGHSTITMKK 185 Query: 171 VLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQ 229 +L ++ + D+GGG+GA +S YP K FD+P VV + H Sbjct: 186 ILETYNGFEGLKSIVDVGGGSGATLNMIISKYPTIKGINFDLPHVVGDSPIH------PG 239 Query: 230 IDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE- 288 ++ GD F +P+ D L + H W+D C +L+ Y ++V E ++ E Sbjct: 240 VEHVGGDMFAS-VPKGDAIFLKWIFHSWSDEDCLRILKNCYEALADNKKVIVAEFIIPEV 298 Query: 289 ----DRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQ 330 D + L ++ + G+ERT + L +SAGF+ F+ Sbjct: 299 PGGSDDATKSVVHLDAVMLAYVPGGKERTEKEFEALATSAGFKSFR 344 >1FP1-D nrPDB Length = 372 Score = 265 bits (678), Expect = 1e-71, Method: Composition-based stats. Identities = 82/350 (23%), Positives = 144/350 (41%), Gaps = 34/350 (9%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGP---LDVAAVAAGVRAS---- 56 +ED A + VL AA +L +F+++A+A P + + +A+ + AS Sbjct: 20 TEDSACLSAMVLTTNLVYPAVLNAAIDLNLFEIIAKATPPGAFMSPSEIASKLPASTQHS 79 Query: 57 --AHGTELLLDICVSLKLLKVETR----GGKAFYRNTELSSDYLTTVSPTSQCSMLKYMG 110 + + +L + S +L TR GG + YL S+ + + Sbjct: 80 DLPNRLDRMLRLLASYSVLTSTTRTIEDGGAERVYGLSMVGKYLVPDE--SRGYLASFTT 137 Query: 111 RTSY----RCWGHLADAV-REGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWS 165 Y + W + +AV E + + GV E + + F +++ +V + Sbjct: 138 FLCYPALLQVWMNFKEAVVDEDIDLFKNVHGVTKYEFMG---KDKKMNQIFNKSMVDVCA 194 Query: 166 VNGRSVLTAFD-LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSF 224 + +L + + D+GGG+G + +S YP K FD+P+V+ A Sbjct: 195 TEMKRMLEIYTGFEGISTLVDVGGGSGRNLELIISKYPLIKGINFDLPQVIENAPPL--- 251 Query: 225 QEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIES 284 I+ GD F +P+ D IL V H+W+D KC L + P G ++++E Sbjct: 252 ---SGIEHVGGDMFAS-VPQGDAMILKAVCHNWSDEKCIEFLSNCHKALSPNGKVIIVEF 307 Query: 285 LLDEDRRGPLLTQL---YSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQF 331 +L E+ ++L M + G+ERT Y L +GF FQ Sbjct: 308 ILPEEPNTSEESKLVSTLDNLMFITVGGRERTEKQYEKLSKLSGFSKFQV 357 >4Z2Y-A nrPDB Length = 359 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 94/340 (27%), Positives = 146/340 (42%), Gaps = 14/340 (4%) Query: 10 RLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVS 69 + GF +Q L A L + DLLA+ G DV +A+ A A LL V Sbjct: 17 HRMQQLIYGFFTAQTLHVAVRLRIPDLLAD--GARDVGDLASATGADAPSLRRLLRALVF 74 Query: 70 LKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRN 129 L++L + TE V+ + + +L G S+ WG L +VR G Sbjct: 75 LEVL---DEPAPGTFALTEQGEVLRADVTGSMRELVLLLSGPESWAAWGQLEHSVRTGEV 131 Query: 130 QYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGG 189 + G F + + F A+ E ++L+A+D + D+GGG Sbjct: 132 AWEHVHG---RSCFDHLMADPQRQAAFNAAMAEGSRAFVPTLLSAYDFGDLRTVVDVGGG 188 Query: 190 AGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEADLY 248 +GAL ++ +P + TVFD P+ V A + + Q ++ + GDFF P AD Y Sbjct: 189 SGALLAGVLAAHPHLRGTVFDTPDGVADAARTVAEQGVADRCGVETGDFFVSVPPGADAY 248 Query: 249 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQ---LYSLNMLV 305 +L VLHDW D +C +L + +P ++++ESL+ + LNM+V Sbjct: 249 VLKSVLHDWDDEQCVEVLRTVRRAVRPDSRVILVESLMPTTVTTAPSVAQVVMNDLNMMV 308 Query: 306 QTEGQERTPTHYHMLLSSAGFRDFQFKKTGA--IYDAILA 343 G+ERT + LL AGFR A + + A Sbjct: 309 CHGGRERTVAEFRELLRVAGFRLESVTPCPAPSVVGILEA 348 >2IP2-A nrPDB Length = 334 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 73/332 (21%), Positives = 137/332 (41%), Gaps = 14/332 (4%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 M +S A R L G S+ ++ A LG+ DL+ + +AA V + A Sbjct: 1 MNNSNLAAARNLIQVVTGEWKSRCVYVATRLGLADLIESGIDSDE--TLAAAVGSDAERI 58 Query: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 L+ + V+ ++ + +TR G Y NT S +L S M+ + G + W Sbjct: 59 HRLMRLLVAFEIFQGDTRDG---YANTPTS--HLLRDVEGSFRDMVLFYGEEFHAAWTPA 113 Query: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180 +A+ G + FG E+ ++ + R +F+ A++ ++ + D Sbjct: 114 CEALLSGTPGFELAFG---EDFYSYLKRCPDAGRRFLLAMK-ASNLAFHEIPRLLDFRG- 168 Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFS-FQEEEQIDFQEGDFFK 239 D+GGG+G L K + P + + D + A+ + S E++ GD + Sbjct: 169 RSFVDVGGGSGELTKAILQAEPSARGVMLDREGSLGVARDNLSSLLAGERVSLVGGDMLQ 228 Query: 240 DPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLY 299 + D+Y+L+R++ D + LL G ++VIE + P ++ L+ Sbjct: 229 EVPSNGDIYLLSRIIGDLDEAASLRLLGNCREAMAGDGRVVVIERTISASEPSP-MSVLW 287 Query: 300 SLNMLVQTEGQERTPTHYHMLLSSAGFRDFQF 331 +++ + G+ RT LL GF + Sbjct: 288 DVHLFMACAGRHRTTEEVVDLLGRGGFAVERI 319 >1ZG3-A nrPDB Length = 358 Score = 250 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 88/366 (24%), Positives = 140/366 (38%), Gaps = 36/366 (9%) Query: 2 GSSEDQAYRL---LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAH 58 GS E + Y L + F+ S L +A ELG+ D + P+ ++ +A+ ++ Sbjct: 1 GSEESELYHAQIHLYKHVYNFVSSMALKSAMELGIADAIHNHGKPMTLSELASSLKLHPS 60 Query: 59 GTELLLDICVSLKLLKVETRG----------GKAFYRNTELSSDYLTTVSPTSQCSMLK- 107 +L L + + Y T S L + PT S++K Sbjct: 61 KVNILHRFLRLLTHNGFFAKTIVKGKEGDEEEEIAYSLTP-PSKLLISGKPTCLSSIVKG 119 Query: 108 YMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVN 167 + +S W E + Q L F E F + E + Q+ + + Sbjct: 120 ALHPSSLDMWSSSKKWFNEDKEQTL--FECATGESFWDFLNKDSES-STLSMFQDAMASD 176 Query: 168 GRSVLTAFD-----LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHF 222 R + D+GGG G + K ++P K TVFD P+VV Sbjct: 177 SRMFKLVLQENKRVFEGLESLVDVGGGTGGVTKLIHEIFPHLKCTVFDQPQVVG------ 230 Query: 223 SFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTC---KPGGGI 279 + E ++F GD FK +P AD +L VLHDW D + +L+ G + Sbjct: 231 NLTGNENLNFVGGDMFKS-IPSADAVLLKWVLHDWNDEQSLKILKNSKEAISHKGKDGKV 289 Query: 280 LVIESLLDEDRRGPLLTQL---YSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGA 336 ++I+ +DE LT+L Y L ML G+ERT + L+ AGF ++ Sbjct: 290 IIIDISIDETSDDRGLTELQLDYDLVMLTMFLGKERTKQEWEKLIYDAGFSSYKITPISG 349 Query: 337 IYDAIL 342 I Sbjct: 350 FKSLIE 355 >1FP2-A nrPDB Length = 352 Score = 247 bits (631), Expect = 4e-66, Method: Composition-based stats. Identities = 71/348 (20%), Positives = 137/348 (39%), Gaps = 25/348 (7%) Query: 7 QAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAH---GTELL 63 +A LL + F+ S L A E+ + +++ P+ ++ + + ++ + L Sbjct: 15 KAQALLYKHIYAFIDSMSLKWAVEMNIPNIIQNHGKPISLSNLVSILQVPSSKIGNVRRL 74 Query: 64 LDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLK-YMGRTSYRCWGHLAD 122 + ++ T+ + Y T ++S+ L S M++ + T + L Sbjct: 75 MRYLAHNGFFEIITKE-EESYALT-VASELLVRGSDLCLAPMVECVLDPTLSGSYHELKK 132 Query: 123 AVREGRNQYLETFGVPAEE-LFTAIYRSEGERLQFMQALQEVWSVNGRSVLT-AFDLSVF 180 + E + L FGV + + ++ F A+ + ++ F Sbjct: 133 WIYE---EDLTLFGVTLGSGFWDFLDKNPEYNTSFNDAMASDSKLINLALRDCDFVFDGL 189 Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD 240 + D+GGG G AK +P K VFD P+VV + + + GD F Sbjct: 190 ESIVDVGGGTGTTAKIICETFPKLKCIVFDRPQVVE------NLSGSNNLTYVGGDMFTS 243 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTC---KPGGGILVIESLLDEDRRGPLLTQ 297 +P AD +L +LH+W D C +L++ G + +I+ ++D+ + +TQ Sbjct: 244 -IPNADAVLLKYILHNWTDKDCLRILKKCKEAVTNDGKRGKVTIIDMVIDKKKDENQVTQ 302 Query: 298 ---LYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAIL 342 L +NM G+ER + L AGF+ ++ I Sbjct: 303 IKLLMDVNMACL-NGKERNEEEWKKLFIEAGFQHYKISPLTGFLSLIE 349 >5I2H-A nrPDB Length = 364 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 88/351 (25%), Positives = 153/351 (43%), Gaps = 24/351 (6%) Query: 12 LNDYANGFMVSQVLFAAC-ELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 + D G +++L A+ L VFD+L E+ PL + + + S T++L+ ++ Sbjct: 20 IFDLFRGNFATELLAASVAHLHVFDILNES--PLSLDELQRRLVLSERATQVLVTGLCAM 77 Query: 71 KLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQ 130 +LL G T L+ ++L T SP S + +++ L + ++ R + Sbjct: 78 QLLTKRLAGEIDL---TPLARNHLVTTSPFSVGGYISLAAQSAGTL--ALVERLKSDRPE 132 Query: 131 YLETFGVPA----EELFTAIYRSEGERLQFMQALQEVWSVNGR-----------SVLTAF 175 E+ A E +A+ R + R + W+V R +L Sbjct: 133 GAESEQGAAFIFREGSESAMDREDSARFLTLSLAGRAWNVAPRFADVLPAGQPGKILKDN 192 Query: 176 DLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQE 234 S ++ D+ GG+G + YP + +FD PEV+ A + ++++ Sbjct: 193 SGSSGRVLLDVAGGSGIYTMAVLQKYPTWRGIIFDRPEVLKIAAELAEQTGVRDRLELHA 252 Query: 235 GDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPL 294 GD + DP P AD +L+ VLHDW +C+ L+ + GG +L+ + LL+ D GPL Sbjct: 253 GDMWVDPFPPADDILLSNVLHDWDRPQCARLVAKATSGLPEGGRLLIHDVLLNSDLTGPL 312 Query: 295 LTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 LYSL + TEG+ + Y ++ A + T A IL+ K Sbjct: 313 EIALYSLALFSLTEGRAYSLEEYRGWIAGADLKYVDCIPTSAHGHLILSEK 363 >4D7K-A nrPDB Length = 353 Score = 242 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 92/344 (26%), Positives = 137/344 (39%), Gaps = 14/344 (4%) Query: 5 EDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLL 64 E A + L Y V+ VL+A +L + DLLA+ GP A +AA + LL Sbjct: 10 ERTAAQRLYQYNVDLKVAFVLYAVAKLHLPDLLAD--GPRTTADLAAATGSDPSRLRRLL 67 Query: 65 DICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMG-RTSYRCWGHLADA 123 L+ D L + P S M + +G L ++ Sbjct: 68 RAAAGADALREVPEDSFEL----APMGDLLRSGHPRSMRGMTTFFAEPDVLAAYGDLVES 123 Query: 124 VREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLM 183 VR G + P + E R +F A+ E LT+FD F Sbjct: 124 VRTGVPAFQLRHREPLYDFLARPQHKEV-RDEFDAAMVEFGQYFADDFLTSFDFGRFTRF 182 Query: 184 CDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPL 242 D+GGG G ++ P + D P V +A + + Q E+++ + GDFF Sbjct: 183 ADIGGGRGQFLAGVLTAVPSSTGVLVDGPAVAASAHKFLASQNLTERVEVRIGDFFDVLP 242 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCK--PGGGILVIESLLDEDRRGPLLTQLYS 300 D Y+L VL DWAD LL RI P +L+++S++ E L ++ Sbjct: 243 TGCDAYVLRGVLEDWADADAVRLLVRIRQAMGDAPEARLLILDSVIGETGE---LGKVLD 299 Query: 301 LNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILAR 344 L+MLV EG+ RT + LL+ AGF G ++ I R Sbjct: 300 LDMLVLVEGEHRTRAQWDDLLARAGFDIVGIHPAGDVWAVIECR 343 >3GXO-A nrPDB Length = 369 Score = 240 bits (613), Expect = 5e-64, Method: Composition-based stats. Identities = 87/327 (26%), Positives = 136/327 (41%), Gaps = 10/327 (3%) Query: 11 LLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 +ND G ++ + A ELGV +LL E P A A G AH L + + Sbjct: 41 TVNDILQGAWKARAIHVAVELGVPELLQEGPRTATALAEATG----AHEQTLRRLLRLLA 96 Query: 71 KLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQ 130 + + G + LS+ L + +R W L +VR G Sbjct: 97 TVGVFDDLGHDDLFAQNALSAVLLPDPASPVATDARFQAAPWHWRAWEQLTHSVRTGEAS 156 Query: 131 YLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGA 190 + G + + R F +A+ V V A+D S D+GGG Sbjct: 157 FDVANGT---SFWQLTHEDPKARELFNRAMGSVSLTEAGQVAAAYDFSGAATAVDIGGGR 213 Query: 191 GALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPEADLYI 249 G+L + +PG + T+ + P V A++ + + ++ + GDFF+ AD+Y+ Sbjct: 214 GSLMAAVLDAFPGLRGTLLERPPVAEEARELLTGRGLADRCEILPGDFFETIPDGADVYL 273 Query: 250 LARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEG 309 + VLHDW D +L RI KP +LVI++L+DE R T L +LV G Sbjct: 274 IKHVLHDWDDDDVVRILRRIATAMKPDSRLLVIDNLIDE--RPAASTLFVDLLLLVLVGG 331 Query: 310 QERTPTHYHMLLSSAGFRDFQFKKTGA 336 ER+ + + LL +G R + GA Sbjct: 332 AERSESEFAALLEKSGLRVERSLPCGA 358 >2QYO-A nrPDB Length = 357 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 67/355 (18%), Positives = 134/355 (37%), Gaps = 34/355 (9%) Query: 7 QAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASA---HGTELL 63 +A LL F+ S L + E+ + +++ P+ ++ + + ++ + + L Sbjct: 15 KAQALLYKNMYAFVDSMSLKWSIEMNIPNIIHNHGKPITLSNLVSILQIPSTKVDNVQRL 74 Query: 64 LDICVSLKLLKVET----RGGKAFYRNTELSSDYLTTVSPTSQCSMLK-YMGRTSYRCWG 118 + ++ T + Y T ++S+ L + M++ + T + Sbjct: 75 MRYLAHNGFFEIITNQELENEEEAYALT-VASELLVKGTELCLAPMVECVLDPTLSTSFH 133 Query: 119 HLADAV-REGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFD- 176 +L V E + G E + ++ + + + + + A Sbjct: 134 NLKKWVYEEDLTLFAVNLGCDLWEFLN-------KNPEYNTLYNDALASDSKMINLAMKD 186 Query: 177 ----LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDF 232 + D+GGG G K +P VFD P+VV + + + Sbjct: 187 CNLVFEGLESIVDVGGGNGTTGKIICETFPKLTCVVFDRPKVVE------NLCGSNNLTY 240 Query: 233 QEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPG---GGILVIESLLDED 289 GD F +P+AD +L VLHDW D C +L++ G ++VI+ +++E Sbjct: 241 VGGDMFIS-VPKADAVLLKAVLHDWTDKDCIKILKKCKEAVTSDGKRGKVIVIDMVINEK 299 Query: 290 RRGPLLTQLYSLN--MLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAIL 342 + LTQ+ L + G+ER + L AGF+D++ + I Sbjct: 300 KDENQLTQIKLLMNVTISCVNGKERNEEEWKKLFIEAGFQDYKISPFTGLMSLIE 354 >4EVI-A nrPDB Length = 388 Score = 232 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 76/360 (21%), Positives = 131/360 (36%), Gaps = 29/360 (8%) Query: 7 QAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGV---RASAHGTELL 63 A + + G++ S L A EL + D++ P+ + +AA + + A L Sbjct: 31 DAQPQVWHHFLGYINSMTLQCALELDIADVIHRHGHPIPLNQLAAALEIPQTKAPFLSRL 90 Query: 64 LDICVSLK----LLKVETRGGKAF---YRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRC 116 + + V L ++ Y LS L ++ + Sbjct: 91 MRMLVHLGYFTQVITKPEDENDDVLPSYWLAPLSRLLLKQNPYNARSLTFCSVHEHLVDP 150 Query: 117 WGHLADAVREGRNQYLETFGVPAEELFTA-IYRSEGERLQFMQALQEVWSVNGRSVLTAF 175 W ++ +R G+ +T A +Y E F Q E + + A Sbjct: 151 WRQMSAWLRTGKEDGKDTPNAFAFAHEGKKVYEVCSEDANFSQLFSEGMAGDSWLFSRAL 210 Query: 176 D------LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQ 229 + D+GGG G +K +P TVFD+P VV KQ Sbjct: 211 VSKCRDAFEGLSSLVDVGGGTGNTSKVIAETFPNIHCTVFDLPHVVSGPKQT-----HPN 265 Query: 230 IDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPG---GGILVIESLL 286 +D++ G+ F D +P AD + VL DW D +L++ G +++ + +L Sbjct: 266 LDYESGNMFTDEIPHADAVLFKWVLCDWPDEPVLKMLKQCKKALTKNGVKGKLMIADHVL 325 Query: 287 DEDR--RGPLLTQLYSLNMLVQ--TEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAIL 342 D + + L+ML EG RT + L + AGF+D++ G + I Sbjct: 326 DHESCNDSNSMGTSLILDMLFMSFLEGSLRTEKQWAKLFAEAGFKDYKITPVGGLRVLIE 385 >6CLW-A nrPDB Length = 364 Score = 231 bits (589), Expect = 3e-61, Method: Composition-based stats. Identities = 92/348 (26%), Positives = 129/348 (37%), Gaps = 17/348 (4%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELL 63 ++D A+ L M L A LGV DL+AE G DV+ +A A + Sbjct: 22 ADDDAFVHLLRL-KDTMTPWALRAVVTLGVPDLVAE--GEKDVSELAQRSGAVPDALRRV 78 Query: 64 LDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTS--YRCWGHLA 121 L + + T A + T LS L + P S L G + R H+ Sbjct: 79 LRLLARRGVF---TEPRPAVFGPTGLSR-LLQSDHPRSMRPWLDLEGPVARGDRTCVHIL 134 Query: 122 DAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP 181 +A+R G + T+G P E + F A+ + S V FD S Sbjct: 135 EALRTGGPVHERTYGRPVWE---DLAARPALGAAFDAAMAQRASWIAGDVAAGFDWSAVR 191 Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE-QIDFQEGDFFKD 240 + D+GGG G + E + PG K T+ D V ++ + E + F G FF Sbjct: 192 HVMDVGGGTGGVLAEVLRARPGLKGTLLDRAPTVAAGREAWGASEAGQRCTFSGGSFFDT 251 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLL--DEDRRGPLLTQL 298 AD +L VLHDWAD +L R P G +L+ E L+ G Sbjct: 252 LPSGADACLLVNVLHDWADEHALAVLRRCAEAVGPRGRVLIAEHLVEEGAGGPGAAGLAE 311 Query: 299 YSLNMLVQTEGQERTPTHYHMLLSSAGFR--DFQFKKTGAIYDAILAR 344 L M++ G+ER L AG R D G A Sbjct: 312 LDLVMMLVYGGRERRLDELADLAGKAGLRIGDVSMTPRGLSLVVCEAE 359 >2R3S-A nrPDB Length = 335 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 72/342 (21%), Positives = 124/342 (36%), Gaps = 22/342 (6%) Query: 11 LLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 L + N + S + AA EL VF +++ G ++A + S G +L D V + Sbjct: 9 LFFNTVNAYQRSAAIKAAVELNVFTAISQ--GIESSQSLAQKCQTSERGMRMLCDYLVII 66 Query: 71 KLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYM-GRTSYRCWGHLADAVREGRN 129 + + G YR T S+ +L S ++++ + L AV +G Sbjct: 67 GFMTKQAEG----YRLTSDSAMFLDRQSKFYVGDAIEFLLSPMITNGFNDLTAAVLKGG- 121 Query: 130 QYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP--LMCDLG 187 A + +QF +A+ + + + + + + + D+ Sbjct: 122 --------TAISSEGTLSPEHPVWVQFAKAMSPMMANPAQLIAQLVNENKIEPLKVLDIS 173 Query: 188 GGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFK-DPLPEA 245 G P +I D V+ AK++ Q + G F+ D + Sbjct: 174 ASHGLFGIAVAQHNPNAEIFGVDWASVLEVAKENARIQGVASRYHTIAGSAFEVDYGNDY 233 Query: 246 DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNML- 304 DL +L LH + C LL +I G ++V + + + DR P +SL ML Sbjct: 234 DLVLLPNFLHHFDVATCEQLLRKIKTALAVEGKVIVFDFIPNSDRITPPDAAAFSLVMLA 293 Query: 305 VQTEGQERTPTHYHMLLSSAGFRDFQFKK-TGAIYDAILARK 345 G T Y + S+AGF Q I+A K Sbjct: 294 TTPNGDAYTFAEYESMFSNAGFSHSQLHSLPTTQQQVIVAYK 335 >4X3Q-A nrPDB Length = 355 Score = 221 bits (563), Expect = 4e-58, Method: Composition-based stats. Identities = 83/348 (23%), Positives = 140/348 (40%), Gaps = 20/348 (5%) Query: 3 SSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTEL 62 SSE A L G Q L A C+LG+F+LL E GPL VA +R ++ Sbjct: 2 SSELSA---LVPVLFGHAAFQQLNAGCQLGLFELLHE-RGPLSAEEVADALRLPRRSADI 57 Query: 63 LLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLAD 122 LL +L L V G + + + + P +++Y + +Y+ + Sbjct: 58 LLLGTTALGLSTVTDGGY---RNGAPIGAAFRDGLWPV-LRDIVQYQDKIAYQPAADYVE 113 Query: 123 AVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPL 182 ++R G+N + F +L++ + G F + + ++ +L D + Sbjct: 114 SLRTGQNAGIRHFPGTTRDLYSRLAAVPGLEELFYRGMHAWSQLSNPVLLAQPDFTRVHR 173 Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDP 241 + D+GGG A +P ++TV D P + A++ + EE++ D F D Sbjct: 174 VLDVGGGDAVNAVALARAHPSLRVTVLDRPGALEVARKTIAEAGLEERVRTHAADIFTDS 233 Query: 242 LPEA-DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYS 300 P D + A L W+ + LL + Y +PGG +LV + D+DR GPL L + Sbjct: 234 YPAGHDCVLFAHQLVIWSPEQNLTLLRKAYDAVEPGGRVLVFNAFTDDDRTGPLYAALDN 293 Query: 301 LNMLVQTEGQERTPTHYHM---LLSSAGFRDF------QFKKTGAIYD 339 + + T + L AGF D + G + Sbjct: 294 VYFTTLPF-RHSTIHRWADCESWLREAGFTDVGRTAPPGWTPHGVVSG 340 >6I5Z-A nrPDB Length = 393 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 75/353 (21%), Positives = 131/353 (37%), Gaps = 38/353 (10%) Query: 21 VSQVLFAACELGVFDLLAEAPG--PLDVAAVAAGVRASAHGT------ELLLDICVSLKL 72 + L AA EL VF L+++ + + +A+ + + + + +L + + + Sbjct: 51 IPMALRAAMELNVFQLISKFGTDAKVSASEIASKMPNAKNNPEAAMYLDRILRLLGASSI 110 Query: 73 LKVET------RGGKA------FYRNTELSSDYLTTVSPTS--QCSMLKYMGRTSYRCWG 118 L V T RGG Y T S + +L + + Sbjct: 111 LSVSTTKKSINRGGDDVVVHEKLYGLTNSSCCLVPRQEDGVSLVEELLFTSDKVVVDSFF 170 Query: 119 HLADAVRE-GRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFD- 176 L V E + G ++F F + V +V +D Sbjct: 171 KLKCVVEEKDSVPFEVAHGA---KIFEYAATEPRMNQVFNDGMAVFSIVVFEAVFRVYDG 227 Query: 177 LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGD 236 + D+GGG G + ++ YP + FD+P V+ A Q+ ++ GD Sbjct: 228 FLDMKELLDVGGGIGTSVSKIVAKYPLIRGVNFDLPHVISVAPQY------PGVEHVAGD 281 Query: 237 FFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLT 296 F++ +P+ +L VLHDW D +C LL+ +++ GG +L+IE +L + + Sbjct: 282 MFEE-VPKGQNMLLKWVLHDWGDERCVKLLKNCWNSLPVGGKVLIIEFVLPNELGNNAES 340 Query: 297 ----QLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAILARK 345 L M + G+ERT + Y L +AGF I K Sbjct: 341 FNALIPDLLLMALNPGGKERTISEYDDLGKAAGFIKTIPIPISNGLHVIEFHK 393 >1XDU-A nrPDB Length = 374 Score = 213 bits (543), Expect = 7e-56, Method: Composition-based stats. Identities = 78/328 (23%), Positives = 127/328 (38%), Gaps = 12/328 (3%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELL 63 ++ LL + N + L A L + D L G +A +A L Sbjct: 13 TDQDLDVLLKNLGN-LVTPMALRVAATLRLVDHL--LAGADTLAGLADRTDTHPQALSRL 69 Query: 64 LDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYR--CWGHLA 121 + + +L+ + G+ R T L L P Q + L G S+ + L Sbjct: 70 VRHLTVVGVLEGGEKQGRPL-RPTRL-GMLLADGHPAQQRAWLDLNGAVSHADLAFTGLL 127 Query: 122 DAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP 181 D VR GR Y +G P E +A F + + + A+D S Sbjct: 128 DVVRTGRPAYAGRYGRPFWEDLSADV---ALADSFDALMSCDEDLAYEAPADAYDWSAVR 184 Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKD 240 + D+GGG G + P + T+ ++ A++ F+ +++ EGDFFK Sbjct: 185 HVLDVGGGNGGMLAAIALRAPHLRGTLVELAGPAERARRRFADAGLADRVTVAEGDFFKP 244 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESL-LDEDRRGPLLTQLY 299 AD+ +L+ VL +W+D +L +PGG +LV++ ++ D + L Sbjct: 245 LPVTADVVLLSFVLLNWSDEDALTILRGCVRALEPGGRLLVLDRADVEGDGADRFFSTLL 304 Query: 300 SLNMLVQTEGQERTPTHYHMLLSSAGFR 327 L ML G+ RT L SAG Sbjct: 305 DLRMLTFMGGRVRTRDEVVDLAGSAGLA 332 >3MCZ-A nrPDB Length = 352 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 77/334 (23%), Positives = 135/334 (40%), Gaps = 25/334 (7%) Query: 3 SSEDQAYRL----LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAH 58 S+ED+A L ++ + S +L A +FDL P +VAA V A Sbjct: 15 STEDKAALTSVVDLVKLSDQYRQSAILHYAVADKLFDLTQTGRTPAEVAASFGMVEGKAA 74 Query: 59 GTELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWG 118 +L L + T+ G A +RNT L+ YLTT S ++++ + W Sbjct: 75 ILL------HALAALGLLTKEGDA-FRNTALTERYLTTTSADYIGPIVEHQ-YLQWDNWP 126 Query: 119 HLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLS 178 L + +R + E F R+ R F A+ + V + Sbjct: 127 RLGEILRSEKP-----LAFQQESRFAHDTRA---RDAFNDAMVRLSQPMVDVVSELGVFA 178 Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDF 237 + DL GG G + + +P ++D+P A++ + +++F E + Sbjct: 179 RARTVIDLAGGHGTYLAQVLRRHPQLTGQIWDLPTTRDAARKTIHAHDLGGRVEFFEKNL 238 Query: 238 FKDPLPE---ADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPL 294 E AD+ +L LH + + ++ KPGG +L++ +++DR P Sbjct: 239 LDARNFEGGAADVVMLNDCLHYFDAREAREVIGHAAGLVKPGGALLILTMTMNDDRVTPA 298 Query: 295 LTQLYSLNMLVQTEGQERTPTHY-HMLLSSAGFR 327 L+ +SL+M+V T E PT + ++ AG Sbjct: 299 LSADFSLHMMVNTNHGELHPTPWIAGVVRDAGLA 332 >5W7R-A nrPDB Length = 429 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 72/343 (20%), Positives = 125/343 (36%), Gaps = 26/343 (7%) Query: 20 MVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRG 79 + L E GVF + + + + ++A +L+ + ++ L Sbjct: 93 VKVASLRTLFEAGVFHAMPKGGASMTASEISAQTGLDKG---ILIRLMRAVTPLGPFHEV 149 Query: 80 GKAFYRNTELSSDYLTTVSPTSQCSMLKY-MGRTSYRC----WGHLADAVREGRNQYLET 134 G+ Y +T S YLT M + G C + DA+ N + Sbjct: 150 GEEEYAHTPFSEAYLTADIAGCFPVMSNFIFGPVLQICDFLRQNNWKDAITTRNNPFTLA 209 Query: 135 FGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVL-----TAFDLSVFPLMCDLGGG 189 P E +F +Y++ +A + + + D+ G Sbjct: 210 HNCPGETMFEHLYKNSKNVAPVTKAEAADVDQIAMDLYPWEERLSDAKGSNATLVDIAGS 269 Query: 190 AGALAKECMSLYP---GCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKD--PLPE 244 G + M+L P GC+ V D+ V+ +H E I+ Q DF K P+ Sbjct: 270 HGNGTRAIMALAPKLNGCRFIVQDLEPVIG---EHSQALRAEGIEPQVYDFLKQEQPVHG 326 Query: 245 ADLYILARVLHDWAD-GKCSHLLERIYHTC-KPGGGILVIESLLDEDRRGPLLTQLYSLN 302 A +Y RV HDW D + +L+ + IL+ + ++ E G ++ + Sbjct: 327 ASIYYFRRVFHDWPDLPEGKKILDNTRAAMSREHSRILIHDIIVPE--IGATMSHAWQDL 384 Query: 303 MLVQTEGQERTPTHYHMLLSSAGFRDFQ-FKKTGAIYDAILAR 344 L+ G ERT + LL AG + ++K G + I AR Sbjct: 385 SLMAIGGMERTEKDFARLLDIAGLALVKVWRKPGDMMGIIEAR 427 >4WXH-A nrPDB Length = 367 Score = 200 bits (508), Expect = 8e-52, Method: Composition-based stats. Identities = 84/327 (25%), Positives = 128/327 (39%), Gaps = 14/327 (4%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELL 63 + A R L + V+ A L + D + G V A+AA L Sbjct: 22 QQIDALRTLIRLGSLH-TPMVVRTAATLRLVDHI--LAGARTVKALAARTDTRPEALLRL 78 Query: 64 LDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYR--CWGHLA 121 + V++ LL+ + G EL +D P +Q + + + L Sbjct: 79 IRHLVAIGLLEEDAPGEFVPTEVGELLAD----DHPAAQRAWHDLTQAVARADISFTRLP 134 Query: 122 DAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP 181 DA+R GR Y +G P + + R F L V + A+D + Sbjct: 135 DAIRTGRPTYESIYGKP---FYEDLAGRPDLRASFDSLLACDQDVAFDAPAAAYDWTNVR 191 Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKD 240 + D+GGG G A P TV ++ V TA+ + + +++D EGDFF+ Sbjct: 192 HVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTARSYLKDEGLSDRVDVVEGDFFEP 251 Query: 241 PLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIES-LLDEDRRGPLLTQLY 299 +AD IL+ VL +W D +L R +PGG IL+ E L E+ + Sbjct: 252 LPRKADAIILSFVLLNWPDHDAVRILTRCAEALEPGGRILIHERDDLHENSFNEQFSTEL 311 Query: 300 SLNMLVQTEGQERTPTHYHMLLSSAGF 326 L MLV G RT + L +SAG Sbjct: 312 DLRMLVFLGGALRTREKWDGLAASAGL 338 >3LST-A nrPDB Length = 348 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 76/335 (22%), Positives = 134/335 (40%), Gaps = 14/335 (4%) Query: 7 QAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDI 66 Q+ L + A G+ + L AA +GV D L + GP A +AA A +L + Sbjct: 21 QSALALYEEAMGYTYAAALRAAAAVGVADHLVD--GPRTPAELAAATGTDADALRRVLRL 78 Query: 67 CVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGH-LADAVR 125 +++ + T L + SP + + T + H +A A+ Sbjct: 79 LAVRDVVR----ESDGRFALT-DKGAALRSDSPVPARAGILMFTDTMFWTMSHRVASALG 133 Query: 126 EGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCD 185 R + + FG + F E + + ++ V + + A D + D Sbjct: 134 PERPAFADIFGSSLDAYFDGDAEVEA---LYYEGMETVSAAEHLILARAGDFPATGTVAD 190 Query: 186 LGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA 245 +GGG G + +PG + + D EVV + + + EGDF ++ +P A Sbjct: 191 VGGGRGGFLLTVLREHPGLQGVLLDRAEVVAR-HRLDAPDVAGRWKVVEGDFLRE-VPHA 248 Query: 246 DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLV 305 D+++L R+LH+W D +L G +LVI++++ E ++ ML Sbjct: 249 DVHVLKRILHNWGDEDSVRILTNCRRVMPAHGRVLVIDAVVPEGNDAHQ-SKEMDFMMLA 307 Query: 306 QTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDA 340 GQERT L ++AG R + T ++ Sbjct: 308 ARTGQERTAAELEPLFTAAGLRLDRVVGTSSVMSI 342 >1X1B-A nrPDB Length = 359 Score = 196 bits (499), Expect = 9e-51, Method: Composition-based stats. Identities = 71/340 (20%), Positives = 140/340 (41%), Gaps = 30/340 (8%) Query: 9 YRLLNDYAN-GFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDIC 67 Y N+ G + + AA EL +F +AE GP D+A +AA + E+LL+ Sbjct: 31 YHRANELVFKGLIEFSCMKAAIELDLFSHMAE--GPKDLATLAADTGSVPPRLEMLLETL 88 Query: 68 VSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTS----QCSMLKYMGRTSYRCWGHLADA 123 ++++ +E + TE + DY+ + +P Q + K M + + L+ A Sbjct: 89 RQMRVINLE----DGKWSLTEFA-DYMFSPTPKEPNLHQTPVAKAMAFLADDFYMGLSQA 143 Query: 124 VREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLM 183 VR G+ + P +Y E R A+Q +L L M Sbjct: 144 VR-GQKNFKGQVPYPPVTREDNLYFEEIHRSNAKFAIQ--------LLLEEAKLDGVKKM 194 Query: 184 CDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPL 242 D+GGG G ++ + +P T+ ++P + ++ + + +++ D +K+ Sbjct: 195 IDVGGGIGDISAAMLKHFPELDSTILNLPGAIDLVNENAAEKGVADRMRGIAVDIYKESY 254 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLN 302 PEAD + R+L+ + + + ++ + + GG +L+++ ++D D P L Sbjct: 255 PEADAVLFCRILYSANEQLSTIMCKKAFDAMRSGGRLLILDMVID-DPENPNFDYLSHYI 313 Query: 303 M-----LVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAI 337 + +E Y +L S G++D + Sbjct: 314 LGAGMPFSVLGFKE--QARYKEILESLGYKDVTMVRKYDH 351 >3DP7-A nrPDB Length = 363 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 61/353 (17%), Positives = 137/353 (38%), Gaps = 33/353 (9%) Query: 7 QAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDI 66 +A RL + A G +V QV + G+F LL+ + ++ + + ++LL+ Sbjct: 14 EAQRLAQEIAFGPVVFQVSRLMLKFGIFQLLSGKREGYTLQEISGRTGLTRYAAQVLLEA 73 Query: 67 CVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVRE 126 +++ + +E L +D + V+ +++ +Y+ HL +A+ Sbjct: 74 SLTIGTILLEEDRYVLAKAGWFLLNDKMARVN-------MEFNHDVNYQGLFHLEEALLN 126 Query: 127 GRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVW---------SVNGRSVLTAFDL 177 GR + L+ FG + IY Q + +Q+ W G+++ F Sbjct: 127 GRPEGLKVFGE-----WPTIYEGLS---QLPEQVQKSWFGFDHFYSDQSFGKALEIVFSH 178 Query: 178 SVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAK-QHFSFQEEEQIDFQEGD 236 + D+GG G A +C+ ++T+ D+P+ + + Q E+I + Sbjct: 179 HP-KRLLDIGGNTGKWATQCVQYNKEVEVTIVDLPQQLEMMRKQTAGLSGSERIHGHGAN 237 Query: 237 FFKD--PLPEA-DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGP 293 P P D +++ L +++ + +L R+ + + ++E+L D R Sbjct: 238 LLDRDVPFPTGFDAVWMSQFLDCFSEEEVISILTRVAQSIGKDSKVYIMETLWDRQRYET 297 Query: 294 LLTQLYSLNM----LVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDAIL 342 L +++ + + + +AG + + + +IL Sbjct: 298 ASYCLTQISLYFTAMANGNSKMFHSDDLIRCIENAGLEVEEIQDNIGLGHSIL 350 >3I64-A nrPDB Length = 332 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 71/331 (21%), Positives = 115/331 (34%), Gaps = 16/331 (4%) Query: 8 AYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDIC 67 A + + A L V D +A A +A+ A A + LL Sbjct: 5 AAHIGLRALADLATPMAVRVAATLRVADHIAAGHR--TAAEIASAAGAHADSLDRLLRHL 62 Query: 68 VSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYR--CWGHLADAVR 125 V++ L TR G+ Y TE L + L + LA ++R Sbjct: 63 VAVGLF---TRDGQGVYGLTEFGEQ-LRDDHAAGKRKWLDMNSAVGRGDLGFVELAHSIR 118 Query: 126 EGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCD 185 G+ Y +G + + F + ++ + +D + + D Sbjct: 119 TGQPAYPVRYGT---SFWEDLGSDPVLSASFDTLMSHHLELDYTGIAAKYDWAALGHVVD 175 Query: 186 LGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPE 244 +GGG+G L ++ + TV D+ A + F + G FF Sbjct: 176 VGGGSGGLLSALLTAHEDLSGTVLDLQGPASAAHRRFLDTGLSGRAQVVVGSFFDPLPAG 235 Query: 245 ADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNML 304 A Y+L+ VLHDW D +L R GG +LVIE++ ++ G + L ML Sbjct: 236 AGGYVLSAVLHDWDDLSAVAILRRCAEAAGSGGVVLVIEAVAGDEHAGTGM----DLRML 291 Query: 305 VQTEGQERTPTHYHMLLSSAGFRDFQFKKTG 335 G+ER+ L + AG Sbjct: 292 TYFGGKERSLAELGELAAQAGLAVRAAHPIS 322 >6J1O-A nrPDB Length = 387 Score = 116 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 52/332 (15%), Positives = 104/332 (31%), Gaps = 23/332 (6%) Query: 11 LLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSL 70 + + V +LG+F L++ P +A + LL S+ Sbjct: 43 TVMRMSLDTCQVAVARIGSDLGLFKHLSQCASPQSAEELADHLGCGRELMSRLLRYMASV 102 Query: 71 KLLKVETRGGKAFYRNT-----ELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVR 125 ++++ T + ++ + R + + DA Sbjct: 103 RMVQQTDDIKYISSNITQTLAVPGLEAGMRHAFENLWPVLMALPDFLAERKYPDIVDAKD 162 Query: 126 EGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWS----VNGRSVLTAFDLSVFP 181 + + F ++ F + F L + + S P Sbjct: 163 T---AFQKAFN-TDQDCFHWLATQPTRIANFKVLLTDERTPNFLSTFPLEKELGSWSAEP 218 Query: 182 ---LMCDLGGGAGALAKECMSLYPGC--KITVFDIPEVVWTAKQHFSFQEEEQIDFQEGD 236 L D+GGG G YP ++ + D+P V+ A+ I+ + Sbjct: 219 EKALFVDIGGGMGHACIRLREKYPNQPGRVILQDLPPVLQAAQATLPLSG---IESMPHN 275 Query: 237 FFK-DPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLL 295 F P+ A Y L +L D+ D + +L+ I I++ + + E Sbjct: 276 FHTPQPVQGAKFYFLRLILRDFPDHQALEILQNIVPAMDAESRIVIDDGVPPEKGARWAE 335 Query: 296 TQLYSLNMLVQTEGQERTPTHYHMLLSSAGFR 327 T + ++ +ERT + L + AG + Sbjct: 336 TGT-DICIMSALGSKERTQRQWEELAAKAGLQ 366 >4KIC-A nrPDB Length = 357 Score = 79.1 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 65/352 (18%), Positives = 120/352 (34%), Gaps = 47/352 (13%) Query: 4 SEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELL 63 SE QA R + D N + S + AA ELG D L E G LDV+ A + Sbjct: 26 SEAQARRAVADIFNSTLASSAIGAAWELGALDELREN-GKLDVSDFAVRHDLHEPAVVGM 84 Query: 64 LDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADA 123 S+ +++ E T + Y S+ ++ + S + + Sbjct: 85 FTALASVGIVRRE--------GATVVVGPYF--DEANHHRSLFHWLNQGSGELFRRMPQV 134 Query: 124 VREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVW-SVNGRSVLTAFDLSVFP- 181 + P E Y+ + + + A +E+ + A D + Sbjct: 135 L-------------PNENRTGKFYQRDAGAISY--ACREISERYFDPAFWAAVDGLGYTP 179 Query: 182 -LMCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQE-EEQIDFQEGDFF 238 + DLG G+G + +PG + DI + A++ + + +QI F GD Sbjct: 180 TTVADLGSGSGERLIQIARRFPGVRGLGVDIADGAIAMAEKEVAAKGFGDQISFVRGDAR 239 Query: 239 K-----DPLPEADLYILARVL--HD-WADGKCSHLLERIYHTCKPGGGILVIESLLD--- 287 A++ +L + HD W C L ++ L+ ++ Sbjct: 240 TIDQVSARGEFAEVDLLTCFMMGHDFWPRENCVQTLRKLRAAFPNVRRFLLGDATRTVGI 299 Query: 288 EDRRGPLLTQLYSL--NMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAI 337 DR P+ T + +M+ T + + G+R + ++ Sbjct: 300 PDRELPVFTLGFEFGHDMM---GVYLPTLDEWDGVFEEGGWRCVKKHAIDSL 348 >2GLU-A nrPDB Length = 239 Score = 61.4 bits (147), Expect = 6e-10, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 61/169 (36%), Gaps = 12/169 (7%) Query: 170 SVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGC-KITVFD-IPEVVWTAKQHFSFQEE 227 ++ + + D+G GAG A ++ P + D E+V A + Sbjct: 12 LMIKTAECRAEHRVLDIGAGAGHTA---LAFSPYVQECIGVDATKEMVEVASSFAQEKGV 68 Query: 228 EQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESL 285 E + FQ+G P P+ D+ H ++D + + K G L+++ Sbjct: 69 ENVRFQQGTAESLPFPDDSFDIITCRYAAHHFSD--VRKAVREVARVLKQDGRFLLVDHY 126 Query: 286 LDEDRRGPLLTQLYSLNMLVQTEG-QERTPTHYHMLLSSAGFRDFQFKK 333 ED L + LN L +E + + + + S+ +K Sbjct: 127 APEDPV--LDEFVNHLNRLRDPSHVRESSLSEWQAMFSANQLAYQDIQK 173 >4IV8-A nrPDB Length = 284 Score = 61.0 bits (146), Expect = 8e-10, Method: Composition-based stats. Identities = 34/185 (18%), Positives = 65/185 (35%), Gaps = 16/185 (8%) Query: 160 LQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTA 218 + V +L+ L + D+G G G K Y + DI +++ A Sbjct: 53 ISSGGIVATTKILSDIYLEPNSKVLDIGSGLGGGCKYINEKYD-AHVYGVDICEKMIAIA 111 Query: 219 KQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPG 276 K +++ +++F+ D K PE D+ + L E+ Y KP Sbjct: 112 K--LRNKDKSKVEFEAMDILKKDFPECTFDMIYSRDAILHLPYADKKKLFEKCYKWLKPN 169 Query: 277 GGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTP---THYHMLLSSAGFRDFQFKK 333 G +L+ + D+ + + ++ T Y L+ S F++ Q K Sbjct: 170 GILLITDYCADK-------IENWDEEFKAYINKRKYTLIPIQDYGDLIKSCNFQNVQAKD 222 Query: 334 TGAIY 338 + Sbjct: 223 ISDYW 227 >3MGG-A nrPDB Length = 276 Score = 59.8 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 35/183 (19%), Positives = 66/183 (36%), Gaps = 12/183 (6%) Query: 160 LQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTA 218 L E + + + + G G GA P +IT DI PE + A Sbjct: 18 LSEQAETLEKLLHHDTVYPPGAKVLEAGCGIGAQTVILAKNNPDAEITSIDISPESLEKA 77 Query: 219 KQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDW-ADGKCSHLLERIYHTCKP 275 +++ + + F + + F P ++ D + VL + + L+++ KP Sbjct: 78 RENTEKNGIKNVKFLQANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKV---LKP 134 Query: 276 GGGILVIESLLDE---DRRGPLLTQLYS--LNMLVQTEGQERTPTHYHMLLSSAGFRDFQ 330 GG I VIE G + ++ + + +G + LL +GF + Sbjct: 135 GGTITVIEGDHGSCYFHPEGKKAIEAWNCLIRVQAYMKGNSLVGRQIYPLLQESGFEKIR 194 Query: 331 FKK 333 + Sbjct: 195 VEP 197 >4MWZ-A nrPDB Length = 267 Score = 58.3 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 36/185 (19%), Positives = 69/185 (37%), Gaps = 16/185 (8%) Query: 160 LQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTA 218 + + +L+ L + D+G G G K Y G + DI ++V A Sbjct: 36 ISSGGIIATTKILSDIQLDANSKVLDIGSGLGGGCKYINEKY-GAHVHGVDICEKMVTIA 94 Query: 219 KQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPG 276 K Q++ +I+F+ D K PE+ D+ + + L E+ Y KP Sbjct: 95 K--LRNQDKAKIEFEAKDILKKDFPESTFDMIYSRDSILHLSYADKKMLFEKCYKWLKPN 152 Query: 277 GGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTP---THYHMLLSSAGFRDFQFKK 333 G +L+ + D+ + + + ++ T Y L+ S F++ + K Sbjct: 153 GILLITDYCADK-------IENWDEEFKAYIKKRKYTLMPIQEYGDLIKSCKFQNVEAKD 205 Query: 334 TGAIY 338 + Sbjct: 206 ISDYW 210 >4INE-A nrPDB Length = 454 Score = 55.6 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 42/109 (38%), Gaps = 6/109 (5%) Query: 176 DLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTAKQHFSFQEEEQIDFQE 234 D M D+G G G A++ + G + D+ ++ A + +++ ++ + Sbjct: 238 DFKPGQTMLDIGVGIGGGARQVADEF-GVHVHGIDLSSNMLAIALERLHEEKDSRVKYSI 296 Query: 235 GDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILV 281 D + D + D + L RIY KPGG +L+ Sbjct: 297 TDALVYQFEDNSFDYVFSRDCIQHIPDTE--KLFSRIYKALKPGGKVLI 343 >5F8E-A nrPDB Length = 377 Score = 53.7 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 49/287 (17%), Positives = 95/287 (33%), Gaps = 18/287 (6%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60 M ++E+ R + + ++ ++ + G+ D +A P P +A Sbjct: 21 METTEEFGNRFVAAI-DSAGLAILVSVGHQTGLLDTMAGLP-PATSMEIAEAAGLEERYV 78 Query: 61 ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120 L + ++ VE G + Y + LT + +++ + Sbjct: 79 REWLGGMTTGQI--VEYDAGSSTYSLPAHRAGMLTRAAGPDNLAVIAQFVSLLGEVEQKV 136 Query: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFD-LSV 179 REG F + + F AL V V D L Sbjct: 137 IRCFREGG-----GVPYSEYPRFHKLMAEMS-GMVFDAALI---DVVLPLVDGLPDRLRS 187 Query: 180 FPLMCDLGGGAGALAKECMSLYPGCKITVFD-IPEVVWTAKQHFSFQEEEQIDFQEGDFF 238 + D G G+G K + + T D E V + + F+ D Sbjct: 188 GADVADFGCGSGRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFERHDLA 247 Query: 239 K-DPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIES 284 + D + D+ + +HD + + +L+ IY +PGG +L+++ Sbjct: 248 ELDKVGAYDVITVFDAIHD--QAQPARVLQNIYRALRPGGVLLMVDI 292 >3BUS-A nrPDB Length = 273 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 22/146 (15%), Positives = 45/146 (30%), Gaps = 5/146 (3%) Query: 144 TAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYP- 202 ++ E ++ + ++ D+ + D+G G G A + Sbjct: 26 ENLHFGYWEDAGADVSVDDATDRLTDEMIALLDVRSGDRVLDVGCGIGKPAVRLATARDV 85 Query: 203 GCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADG 260 P+V + + ++ F D P +A D LH D Sbjct: 86 RVTGISISRPQVNQANARATAAGLANRVTFSYADAMDLPFEDASFDAVWALESLHHMPDR 145 Query: 261 KCSHLLERIYHTCKPGGGILVIESLL 286 L + +PGG + + + +L Sbjct: 146 G--RALREMARVLRPGGTVAIADFVL 169 >2PJD-A nrPDB Length = 343 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 56/159 (35%), Gaps = 8/159 (5%) Query: 136 GVPAEELFTAIYRSEGERLQFMQAL--QEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGAL 193 V E F Y +G ++ + + ++ V + +L+ + D+G GAG L Sbjct: 151 PVFDAEKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVL 210 Query: 194 AKECMSLYPGCKITVFD-IPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILAR 252 + P ++T+ D V ++ + E + + F + D+ I Sbjct: 211 SVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEG-EVFASNVFSEVKGRFDMIISNP 269 Query: 253 VLHD---WADGKCSHLLERIYHTCKPGGGI-LVIESLLD 287 HD + L+ GG + +V + L Sbjct: 270 PFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLP 308 >5GM1-A nrPDB Length = 297 Score = 51.7 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 63/205 (30%), Gaps = 14/205 (6%) Query: 139 AEELFTAIYRSEGERLQFMQALQEVWSVNGRS----VLTAFDLSVFPLMCDLGGGAGAL- 193 E + ++ + L + S ++ D + D+G G G Sbjct: 33 GESVHCGLWFPPDAPVPQDMELVTMSSQAQDRYTDYLIETLDPKAGQHLLDIGCGTGRTA 92 Query: 194 AKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILA 251 K ++ + E++ F+ D + P + D Sbjct: 93 LKAARQRGIAVTGVAVSKEQIAAANRLAAGHGLTERLTFEVADAMRLPYEDESFDCAWAI 152 Query: 252 RVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQE 311 L K L + KPGG +LV+ES++ E+ P T L+ + Sbjct: 153 ESLCHMDRAKA---LGEAWRVLKPGGDLLVLESVVTEELTEP-ETALFETLYAANVPPR- 207 Query: 312 RTPTHYHMLLSSAGFRDFQFKKTGA 336 + ++S AGF K A Sbjct: 208 --LGEFFDIVSGAGFHTLSLKDLSA 230 >5E2B-A nrPDB Length = 241 Score = 51.0 bits (120), Expect = 7e-07, Method: Composition-based stats. Identities = 27/164 (16%), Positives = 56/164 (34%), Gaps = 17/164 (10%) Query: 168 GRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKIT-VFDI-PEVVWTAKQHFSFQ 225 R + + + D G G G + K + P + + DI + + AK + + Sbjct: 68 QRFLREGPNKTGTSCALDCGAGIGRITKRLLL--PLFREVDMVDITEDFLVQAKTYLGEE 125 Query: 226 EEEQIDFQEGDF--FKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 + ++ F D+ + V+ D + L R + +P G I++ + Sbjct: 126 GKRVRNYFCCGLQDFTPEPDSYDVIWIQWVIGHLTDQHLAEFLRRCKGSLRPNGIIVIKD 185 Query: 284 SLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFR 327 ++ E L ++ V R ++ SAG Sbjct: 186 NMAQEGVI------LDDVDSSVC-----RDLDVVRRIICSAGLS 218 >1XTP-A nrPDB Length = 254 Score = 50.6 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 48/165 (29%), Gaps = 14/165 (8%) Query: 168 GRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEE 227 R+ + + D G G G + K ++ + + ++ AK+ + Sbjct: 82 SRNFIASLPGHGTSRALDCGAGIGRITKNLLTKLYATTDLLEPVKHMLEEAKRELA--GM 139 Query: 228 EQIDFQEGDFFKDPLP--EADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESL 285 F LP DL ++ D + P G I E+ Sbjct: 140 PVGKFILASMETATLPPNTYDLIVIQWTAIYLTDADFVKFFKHCQQALTPNGYIFFKENC 199 Query: 286 LDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQ 330 DR + L R+ HY L + +G R + Sbjct: 200 STGDR----FLVDKEDSSLT------RSDIHYKRLFNESGVRVVK 234 >4FGZ-A nrPDB Length = 266 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 32/182 (17%), Positives = 63/182 (34%), Gaps = 16/182 (8%) Query: 167 NGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQ 225 + +L+ +L+ + D+G G G Y G DI +V A + Sbjct: 43 ATKKILSDIELNENSKVLDIGSGLGGGCMYINEKY-GAHTHGIDICSNIVNMANERV--S 99 Query: 226 EEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 +I F+ D PE DL + + + L ++ Y KP G +L+ + Sbjct: 100 GNNKIIFEANDILTKEFPENNFDLIYSRDAILHLSLENKNKLFQKCYKWLKPTGTLLITD 159 Query: 284 SLLDEDRRGPLLTQLYSLNMLVQTEGQERTP---THYHMLLSSAGFRDFQFKKTGAIYDA 340 E + + ++ T Y +L++ F++ K ++ Sbjct: 160 YCATEKEN-------WDDEFKEYVKQRKYTLITVEEYADILTACNFKNVVSKDLSDYWNQ 212 Query: 341 IL 342 +L Sbjct: 213 LL 214 >4KRI-A nrPDB Length = 433 Score = 48.3 bits (113), Expect = 4e-06, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 52/153 (33%), Gaps = 11/153 (7%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTAKQHFSFQEEEQIDFQEGDF--F 238 M D+G G G A++ S + G ++ D+ ++ A + +++ ++ + D + Sbjct: 225 RMLDIGVGIGGGARQAASEF-GLQVHGVDLSTNMLAVALERVHKEKDARVTYAVCDACEY 283 Query: 239 KDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQL 298 + D + D L RIY KPGG +L+ + + Sbjct: 284 EFEPNSFDYVFSRDCIQHIKDTD--KLFSRIYRALKPGGKVLITMYGVGHGTLSESFKEY 341 Query: 299 YSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQF 331 S + + GF D + Sbjct: 342 VSQRQYYL-----KNLEQIEEIAKKTGFIDIEV 369 >4KRG-A nrPDB Length = 466 Score = 47.9 bits (112), Expect = 7e-06, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 60/198 (30%), Gaps = 12/198 (6%) Query: 140 EELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPL-----MCDLGGGAGALA 194 + F + ++ + + + + A LS P + D+G G G Sbjct: 13 RDSFKTFWDKYSDKPDTNSMMLNQTAQDLEASDRADILSSLPHLTNKDVVDIGAGIGRFT 72 Query: 195 KECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDF--FKDPLPEADLYILAR 252 T F I + ++ + I +Q GD + DL Sbjct: 73 TVLAETARWVLSTDF-IESFIEKNQERNAHMG--NISYQIGDAVHLQMDEKSVDLVFTNW 129 Query: 253 VLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQER 312 ++ +D + L + G I + ES E G L T + R Sbjct: 130 LMMYLSDREVIEFLLNAMRWLRADGYIHLRESC-SEPSTGRLKTATMHSAVDANPTH-YR 187 Query: 313 TPTHYHMLLSSAGFRDFQ 330 + Y LL + +RD Sbjct: 188 FSSLYIKLLRAIRYRDSD 205 >5UBB-A nrPDB Length = 222 Score = 47.5 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 42/132 (31%), Gaps = 6/132 (4%) Query: 162 EVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKIT-VFDI-PEVVWTAK 219 + R + + D G G G ++K + P + D+ + A+ Sbjct: 43 QASQKFLRKFVGGPGRAGTDCALDCGSGIGRVSKHVLL--PVFNSVELVDMMESFLLEAQ 100 Query: 220 QHFSFQEEEQIDFQEGDF--FKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGG 277 + + ++ + F P D+ + V D L R K G Sbjct: 101 NYLQVKGDKVESYHCYSLQEFTPPFRRYDVIWIQWVSGHLTDKDLLAFLSRCRDGLKENG 160 Query: 278 GILVIESLLDED 289 I++ +++ E Sbjct: 161 IIILKDNVAREG 172 >5WP5-A nrPDB Length = 491 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 27/166 (16%), Positives = 52/166 (31%), Gaps = 12/166 (7%) Query: 167 NGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQ 225 + + DL + D+G G G + + D+ ++ A + Sbjct: 270 TTKEFVAKMDLKPGQKVLDVGCGIGGGDFYMAENFD-VHVVGIDLSVNMISFALERAIGL 328 Query: 226 EEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 + ++F+ D P+ D+ + D L + KPGG +L+ + Sbjct: 329 KCS-VEFEVADCTTKTYPDNSFDVIYSRDTILHIQDKPA--LFRTFFKWLKPGGKVLITD 385 Query: 284 SLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDF 329 + P + + Q Y +L AGF D Sbjct: 386 YCRSAETPSPEFAEY-----IKQRGYDLHDVQAYGQMLKDAGFDDV 426 Score = 32.1 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 35/117 (29%), Gaps = 7/117 (5%) Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDF--- 237 + +LG G G E D E + + + I F D Sbjct: 55 KSVLELGAGIGRFTGELAQKAGEV--IALDFIESAIQKNESVNGHYK-NIKFMCADVTSP 111 Query: 238 -FKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGP 293 K DL +L +D + + ER+ KPGG I ES + Sbjct: 112 DLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSK 168 >2O57-A nrPDB Length = 297 Score = 45.6 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 29/193 (15%), Positives = 60/193 (31%), Gaps = 13/193 (6%) Query: 139 AEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECM 198 E++ +Y+ ++ + +A + L DLG G G A+ + Sbjct: 42 GEDIHVGLYKEPVDQDEIREASLRTDEWLASELAMTGVLQRQAKGLDLGAGYGGAARFLV 101 Query: 199 SLYPGCKITVFDIPEVVWTAKQHFSFQE--EEQIDFQEGDFFKDPLPE--ADLYILAR-V 253 + G I +I V + ++ Q + I + G F + P + D Sbjct: 102 RKF-GVSIDCLNIAPVQNKRNEEYNNQAGLADNITVKYGSFLEIPCEDNSYDFIWSQDAF 160 Query: 254 LHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERT 313 LH + + KP G + + + + ++ + + L + Sbjct: 161 LHS---PDKLKVFQECARVLKPRGVMAITDPMKEDGIDKSSIQPILDRIKLHDMG----S 213 Query: 314 PTHYHMLLSSAGF 326 Y L G Sbjct: 214 LGLYRSLAKECGL 226 >4FS8-A nrPDB Length = 383 Score = 45.6 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 63/178 (35%), Gaps = 29/178 (16%) Query: 181 PLMCDLGGGAGA---LAKECMSLYPGCKITVFD-IPEVVWTAKQHFSFQEE--------E 228 + DLG G G LA + + + K+ D + + A+++ + E Sbjct: 85 ATVLDLGCGTGRDVYLASKLVGEH--GKVIGVDMLDNQLEVARKYVEYHAEKFFGSPSRS 142 Query: 229 QIDFQEGDFFKDPLPEAD---------LYILARVLHDWADGKCSHLLERIYHTCKPGGGI 279 + F +G F + L A+ +++ + + + K L + I+ + GG + Sbjct: 143 NVRFLKG--FIENLATAEPEGVPDSSVDIVISNCVCNLSTNK-LALFKEIHRVLRDGGEL 199 Query: 280 LVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAI 337 + D + + G + L++ AGFRD + G + Sbjct: 200 YFSDVYADRRL---SEAAQQDPILYGECLGGALYLEDFRRLVAEAGFRDVRLVSVGPV 254 >5MGZ-A nrPDB Length = 236 Score = 45.2 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 59/162 (36%), Gaps = 9/162 (5%) Query: 144 TAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPG 203 AI SE E M + +L ++ + DL G+G L S +P Sbjct: 4 EAITGSEAEAFHRMGSQASHRYDEFVDLLVGAGIADGQTVVDLCCGSGELEVILSSRFPS 63 Query: 204 CKITVFDI-PEVVWTAKQHFSFQEEEQIDFQEGDF-----FKDPLPEADLYILARVLHDW 257 + D+ ++V A+++ + Q + ++F+ GD +D +ADL + H Sbjct: 64 LNLVGVDLSEDMVRIAREYAAEQGKA-LEFRHGDAQLLAGMEDLAGKADLVVSRNAFHRL 122 Query: 258 ADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLY 299 + + + KPGG +L + D Sbjct: 123 TRLPAA--FDTMLRLAKPGGAVLNCSFIHPSDFDESGFRAWV 162 >5WP4-A nrPDB Length = 491 Score = 44.4 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 25/166 (15%), Positives = 50/166 (30%), Gaps = 12/166 (7%) Query: 167 NGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQ 225 + + +L + D+G G G + + D+ ++ A + Sbjct: 270 TTKEFVEKMNLKPGQKVLDVGCGIGGGDFYMAEKFD-VHVVGIDLSVNMISFALERAIGL 328 Query: 226 EEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 ++F+ D P+ D+ + D L + KPGG +L+ + Sbjct: 329 SCS-VEFEVADCTTKHYPDNSFDVIYSRDTILHIQDKPA--LFRTFFKWLKPGGKVLISD 385 Query: 284 SLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDF 329 ++ + Q Y +L AGF D Sbjct: 386 YCRSPKTPSAEFSEY-----IKQRGYDLHDVQAYGQMLKDAGFTDV 426 >3D2L-A nrPDB Length = 243 Score = 44.4 bits (103), Expect = 8e-05, Method: Composition-based stats. Identities = 35/188 (18%), Positives = 56/188 (29%), Gaps = 41/188 (21%) Query: 178 SVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDF 237 + D+G G G Y ++T D+ E + Q + + +DF D Sbjct: 32 EPGKRIADIGCGTGTATLLLADHY---EVTGVDLSEEMLEIAQEKAMETNRHVDFWVQDM 88 Query: 238 FKDPLPE-ADLY-ILARVLHDW-ADGKCSHLLERIYHTCKPGGGILV------------- 281 + LPE D IL L+ + + GG +L Sbjct: 89 RELELPEPVDAITILCDSLNYLQTEADVKQTFDSAARLLTDGGKLLFDVHSPYKMETLFN 148 Query: 282 ----------IESLLDEDRRGPLLTQLYSLNMLVQTE----------GQERT--PTHYHM 319 + D L+ ++ L ++ E +RT P Y Sbjct: 149 GKTYATHAEQSSYIWFADPGEEPLSVVHELTFFIEGEDGRYDRVDETHHQRTYPPEQYIT 208 Query: 320 LLSSAGFR 327 L AGFR Sbjct: 209 WLREAGFR 216 >5M58-A nrPDB Length = 230 Score = 44.0 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 32/138 (23%), Positives = 54/138 (39%), Gaps = 13/138 (9%) Query: 170 SVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEEE 228 +L ++ + DL G+G L S +P + D+ ++V A+ + + Q +E Sbjct: 30 DLLVGAGIADGQTVVDLCCGSGELEIILTSRFPSLNLVGVDLSEDMVRIARDYAAEQGKE 89 Query: 229 QIDFQEGDF-----FKDPLPEADLYILARVLHDWADGKC--SHLLERIYHTCKPGGGILV 281 ++F+ GD +D L +ADL + H +L KPGG IL Sbjct: 90 -LEFRHGDAQSPAGMEDLLGKADLVVSRHAFHRLTRLPAGFDTMLR----LVKPGGAILN 144 Query: 282 IESLLDEDRRGPLLTQLY 299 + L D P Sbjct: 145 VSFLHLSDFDEPGFRTWV 162 >5JE5-A nrPDB Length = 247 Score = 44.0 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 30/177 (16%), Positives = 61/177 (34%), Gaps = 26/177 (14%) Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEEEQIDFQEGDFFK 239 + DL G G +E K+ DI +++ A++ + ++F D Sbjct: 43 KSVLDLACGFGFFGREIYRRG-AAKVVGVDISEKMIELAREESRKYG-DPLEFHVRDVAN 100 Query: 240 -DPLPEADLYILARVLHDWADGKCSH-LLERIYHTCKPGGGILVIESLLDEDRRGPLLTQ 297 +PL + DL A + + + + + + + KP G LV ++ + Sbjct: 101 MEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGK-LVAYTVDPDFSLAKGNFA 159 Query: 298 LYSLNML--VQTEGQERTPTHY------------------HMLLSSAGFRDFQFKKT 334 Y +N+L R + ++ AGF F+++K Sbjct: 160 KYGVNVLNERAWGPGYRHDAEFVTDPPSQFSFYRWSRADYESAIADAGFSHFEWQKP 216 >3I9F-A nrPDB Length = 170 Score = 42.9 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 51/164 (31%), Gaps = 25/164 (15%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPL 242 + D G G G K + ++ + ++ S D + P Sbjct: 21 IVDYGCGNGFYCKYLLEFATKLYCIDINVIALKEVKEKFDSVITLS-------DPKEIPD 73 Query: 243 PEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLTQLYSLN 302 D + A HD D + H++ + K G +++I+ + GP L+ Sbjct: 74 NSVDFILFANSFHDMDDKQ--HVISEVKRILKDDGRVIIIDWRKENTGIGPPLSIRMD-- 129 Query: 303 MLVQTEGQERTPTHYHMLLSSAGFRDFQ-FKKTGAIYDAILARK 345 Y S+ F + F T + +L RK Sbjct: 130 -----------EKDYMGWFSN--FVVEKRFNPTPYHFGLVLKRK 160 >6MRO-A nrPDB Length = 194 Score = 42.9 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 42/105 (40%), Gaps = 6/105 (5%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFK-D 240 D+G G G M GC +T D+ + + + + + +++F G+ + D Sbjct: 35 RALDIGCGRGE--NAIMLAKNGCDVTGIDLAKRAISDAKAKAIERHVKVNFIVGNVLEMD 92 Query: 241 PLP---EADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVI 282 L E D+ I + + H D + ++ K GG ++ Sbjct: 93 QLFTEDEFDIVIDSGLFHVITDEERLLFTRHVHKVLKEGGKYFML 137 >2B3T-A nrPDB Length = 276 Score = 42.5 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEEEQIDFQEGDFF 238 + DLG G GA+A S P C+I D P+ V A+++ + I + D+F Sbjct: 112 RILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKNIHILQSDWF 169 >5BXY-A nrPDB Length = 158 Score = 42.5 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 40/84 (47%), Gaps = 3/84 (3%) Query: 169 RSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQE- 226 +L D+ ++ DLG G G + + G + +I P++V A+++ Sbjct: 14 DRMLELADVDETDVLYDLGSGDGRIVIRAARTH-GARGVGIEIDPDLVKKARKNAKEAGV 72 Query: 227 EEQIDFQEGDFFKDPLPEADLYIL 250 + ++F++GD F+ + EA + L Sbjct: 73 ADLVEFRQGDLFEADISEATVVTL 96 >4DCM-A nrPDB Length = 375 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 20/163 (12%), Positives = 48/163 (29%), Gaps = 11/163 (6%) Query: 128 RNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLG 187 Q + + +L + F + + R + ++ + DLG Sbjct: 174 EPQLADAPQTVSWKLEGTDWTIHNHANVFSR---TGLDIGARFFMQHLPENLEGEIVDLG 230 Query: 188 GGAGALAKECMSLYPGCKITVFD-IPEVVWTAK---QHFSFQEEEQIDFQEGDFFKDPLP 243 G G + + P K+ D P V +++ + + ++ +F + P Sbjct: 231 CGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEP 290 Query: 244 -EADLYILA---RVLHDWADGKCSHLLERIYHTCKPGGGILVI 282 + + H D + K G + ++ Sbjct: 291 FRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIV 333 >3CCF-A nrPDB Length = 279 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 25/145 (17%), Positives = 47/145 (32%), Gaps = 18/145 (12%) Query: 137 VPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKE 196 A+ + A + VW G +L + + DLG G G L ++ Sbjct: 24 GTAKNFWDATLYQDKHSF--------VWQY-GEDLLQLLNPQPGEFILDLGCGTGQLTEK 74 Query: 197 CMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA-DLYILARVLH 255 T + ++ A+Q++ + F D + + D +LH Sbjct: 75 IAQSGAEVLGTD-NAATMIEKARQNY-----PHLHFDVADARNFRVDKPLDAVFSNAMLH 128 Query: 256 DWADGKCSHLLERIYHTCKPGGGIL 280 W + + I+ K GG + Sbjct: 129 -WVKEPEAAI-ASIHQALKSGGRFV 151 >1JG3-A nrPDB Length = 235 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 32/186 (17%), Positives = 60/186 (32%), Gaps = 18/186 (9%) Query: 106 LKYMGRTSYRCWGHLADAVREGRN--------QYLETFGVPAEELFTAIYRSEGERLQFM 157 L + Y W + ++ +L+ + E Y E L Sbjct: 10 LMMDEKELYEKWMRTVEMLKAEGIIRSKEVERAFLKYPRYLSVEDKYKKYAHIDEPLPIP 69 Query: 158 QALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWT 217 +L +L + ++G G+G A + T+ IPE+V Sbjct: 70 AGQTVSAPHMVAIMLEIANLKPGMNILEVGTGSGWNAALISEIVKTDVYTIERIPELVEF 129 Query: 218 AKQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKP 275 AK++ + + GD K P+A D+ I+ + E + K Sbjct: 130 AKRNLERAGVKNVHVILGDGSKGFPPKAPYDVIIVT--------AGAPKIPEPLIEQLKI 181 Query: 276 GGGILV 281 GG +++ Sbjct: 182 GGKLII 187 >1L3B-A nrPDB Length = 192 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 54/145 (37%), Gaps = 12/145 (8%) Query: 150 EGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLM-CDLGGGAGALAKECMSLYPGCKITV 208 + ++ ++ R ++ + D+G G G + E ++ Sbjct: 3 PDDEFIKNPSVPGPTAMEVRCLIMCLAEPGKNDVAVDVGCGTGGVTLELAGRV--RRVYA 60 Query: 209 FDI-PEVVWTAKQHFSFQE-EEQIDFQEGDFFKD--PLPEADLYILARVLHDWADGKCSH 264 D PE + T + + + + EGD + +P+ D+ ++ + G+ Sbjct: 61 IDRNPEAISTTEMNLQRHGLGDNVTLMEGDAPEALCKIPDIDIAVVGG-----SGGELQE 115 Query: 265 LLERIYHTCKPGGGILVIESLLDED 289 +L I KPGG I+V LL+ Sbjct: 116 ILRIIKDKLKPGGRIIVTAILLETK 140 >3OU6-A nrPDB Length = 218 Score = 41.3 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 48/151 (31%), Gaps = 9/151 (5%) Query: 143 FTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP-LMCDLGGGAGALAKECMSLY 201 + + ++ + L + +L G G + L Sbjct: 9 ESQLSYYRARASEYDATFVPYMDSAAPAALERLRAGNIRGDVLELASGTGYWTRHLSGLA 68 Query: 202 PGCKITVFD-IPEVVWTAKQHFSFQEEEQIDFQEGDFFK-DPLPEADLYILARVLHDWAD 259 ++T D E++ A +H + ++F++ D F P + D A L D Sbjct: 69 D--RVTALDGSAEMIAEAGRH----GLDNVEFRQQDLFDWTPDRQWDAVFFAHWLAHVPD 122 Query: 260 GKCSHLLERIYHTCKPGGGILVIESLLDEDR 290 + E + PGG + ++ E R Sbjct: 123 DRFEAFWESVRSAVAPGGVVEFVDVTDHERR 153 >6QMM-B nrPDB Length = 280 Score = 41.3 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 46/139 (33%), Gaps = 24/139 (17%) Query: 180 FPLMCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTAKQHFSFQEE----EQIDFQE 234 + +GGG G +E + ++ + +I VV ++++ +++ + Sbjct: 74 IARVLVIGGGDGGTVREVLRYAEVEQVDLVEIDGRVVELSQEYLGAIGTAWADPRLNVKI 133 Query: 235 GD--FFKDPLPEADLYILARVLHDWADGK-------CSHLLERIYHTCKPGGGILVIESL 285 GD F P+A + +L D +D E KPGG + Sbjct: 134 GDGIAFVQTAPDASYDV---ILVDGSDPAGPAAGLFNREFYENCRRVLKPGG-------V 183 Query: 286 LDEDRRGPLLTQLYSLNML 304 P L M+ Sbjct: 184 FASQAESPDSFLAVHLEMI 202 >5BSZ-A nrPDB Length = 250 Score = 41.0 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 19/155 (12%), Positives = 44/155 (28%), Gaps = 18/155 (11%) Query: 132 LETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAG 191 +G E++ YR G+ + + D+ G G Sbjct: 8 TSVYGDALGEVYDLFYRGRGKDF--------AAEAEWVRRVVRERRPGARSLLDVACGTG 59 Query: 192 ALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFFK---DPLPEADLY 248 + +P P + A++ + + D F + +A Sbjct: 60 EHLAHLVEHFPDAAGVEL-SPAMRAAAERKLTATP-----VHQADMFDFDLGRVFDAVCC 113 Query: 249 ILARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 + + + + + + + GG +LVI+ Sbjct: 114 LTGSIAYAADTAELARAVRAMARHLPVGG-VLVID 147 >6DCC-A nrPDB Length = 309 Score = 39.8 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 5/52 (9%) Query: 236 DFFKDPLPEADLYI----LARVLHDWADGKCSHLLERIYHTCKPGGGILVIE 283 D + PE D+ + V +W D + RIY +PGG ILV+E Sbjct: 186 DLVEAQTPEYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRPGG-ILVLE 236 >4HTF-A nrPDB Length = 285 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 30/159 (18%), Positives = 60/159 (37%), Gaps = 17/159 (10%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEEEQ----IDFQEGD 236 + D GGG G A + G ++ + D+ +++ AKQ + I D Sbjct: 71 RVLDAGGGEGQTAIKMAER--GHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAAQD 128 Query: 237 FFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDRRGPLLT 296 DL + VL AD + +L+ ++ +PGG + ++ ++ Sbjct: 129 VASHLETPVDLILFHAVLEWVADPRS--VLQTLWSVLRPGGVLSLMFYNAHGLLMHNMVA 186 Query: 297 QLYSLNMLVQTEGQERT--------PTHYHMLLSSAGFR 327 + + ++RT PT ++ L AG++ Sbjct: 187 GNFDYVQAGMPKKKKRTLSPDYPRDPTQVYLWLEEAGWQ 225 >3HNR-A nrPDB Length = 220 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 41/123 (33%), Gaps = 6/123 (4%) Query: 170 SVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQ 229 +L F + + G G G L + + E+ AK+ ++ Sbjct: 36 DILEDVVNKSFGNVLEFGVGTGNLTNKLLLAGRTVYGIEPSR-EMRMIAKEKL----PKE 90 Query: 230 IDFQEGDFFKDPLPEA-DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE 288 EGDF +P + D + H D + + + + GG I+ +++ + Sbjct: 91 FSITEGDFLSFEVPTSIDTIVSTYAFHHLTDDEKNVAIAKYSQLLNKGGKIVFADTIFAD 150 Query: 289 DRR 291 Sbjct: 151 QDA 153 >5U19-A nrPDB Length = 341 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%), Gaps = 1/73 (1%) Query: 167 NGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE 226 ++ D+G G+G L+ Y + P V ++ + + Sbjct: 131 EADLLIRLMLRRGGARALDMGCGSGVLSLVLADRYESVLGVDVN-PRAVALSRLNAALNG 189 Query: 227 EEQIDFQEGDFFK 239 + F+EGD F+ Sbjct: 190 LTNVTFREGDMFE 202 >3R9X-B nrPDB Length = 248 Score = 38.6 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 27/75 (36%), Gaps = 6/75 (8%) Query: 169 RSVLTAFDLSVFPLMCDLGGGAGALAKECMSL-YPGCKITVFDIPEVVWTAKQHFSFQEE 227 + + ++ + ++GGG G L K + + D V ++ + Sbjct: 20 KKIAEELNIEEGNTVVEVGGGTGNLTKVLLQHPLKKLYVIELDREMV-----ENLKSIGD 74 Query: 228 EQIDFQEGDFFKDPL 242 E+++ D K P Sbjct: 75 ERLEVINEDASKFPF 89 >4PNE-A nrPDB Length = 302 Score = 37.9 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 31/179 (17%), Positives = 52/179 (29%), Gaps = 10/179 (5%) Query: 161 QEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYP-GCKITVFDIPEVVWTAK 219 Q+ V L + D+G G G A +V A Sbjct: 74 QQAADRLTDLVAERTVLDGGVRLLDVGCGTGQPALRVARDNAIQITGITVSQVQVAIAAD 133 Query: 220 QHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHTCKPGG 277 ++DF D P P+ D + L + ++ + I KPGG Sbjct: 134 CARERGLSHRVDFSCVDAMSLPYPDNAFDAAWAMQSLLEMSEPD--RAIREILRVLKPGG 191 Query: 278 GILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGA 336 + V E + E G ++ T + L +AGF ++ + Sbjct: 192 ILGVTEVVKREAGGGMPVSGDR-----WPTGLRICLAEQLLESLRAAGFEILDWEDVSS 245 >6F5Z-A nrPDB Length = 231 Score = 37.9 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 58/174 (33%), Gaps = 16/174 (9%) Query: 157 MQALQ-EVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFD-IPEV 214 + ++ W ++ + DLG G+G + + D PE+ Sbjct: 16 DKGMEDRHWHTAKHALARMPVEEG-DTVVDLGTGSGYALRALRDTKGIGRGFGLDGSPEM 74 Query: 215 VWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYHT 272 V A+ ++ + + + F GDF P + D + AD H LE I Sbjct: 75 VQNAR---AYTDTDDLSFLVGDFDDLPFDDDSVDHVWSMEAFYYAADPH--HTLEEIARI 129 Query: 273 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGF 326 KPGG + +E+ + S++M + Y AG Sbjct: 130 LKPGGTFYCAVNYYEENVHSHEWQEHISIDMT------RWSHAEYREAFRDAGL 177 >3HM2-A nrPDB Length = 178 Score = 37.1 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 38/109 (34%), Gaps = 16/109 (14%) Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQH-----FSFQEEEQIDFQ 233 + D+GGG+G++A E + P F+ + ++ + ++I Q Sbjct: 25 PHETLWDIGGGSGSIAIEWLRSTPQTTAVCFE---ISEERRERILSNAINLGVSDRIAVQ 81 Query: 234 EGD--FFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGIL 280 +G F D D+ + L + + GG ++ Sbjct: 82 QGAPRAFDDVPDNPDVIFIGGGL------TAPGVFAAAWKRLPVGGRLV 124 >1XDZ-A nrPDB Length = 240 Score = 35.9 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 17/35 (48%) Query: 176 DLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFD 210 D + +CD+G GAG + +P +T+ D Sbjct: 67 DFNQVNTICDVGAGAGFPSLPIKICFPHLHVTIVD 101 >1N2X-A nrPDB Length = 301 Score = 35.6 bits (80), Expect = 0.037, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 32/89 (35%), Gaps = 5/89 (5%) Query: 161 QEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQ 220 Q V R V+ ++ D G G ++ + PGC+I D+ V + Sbjct: 8 QRHIPVMVREVIEFLKPEDEKIILDCTVGEGGHSRAILEHCPGCRIIGIDVDSEVLRIAE 67 Query: 221 HFSFQEEEQIDFQEGDFFKDPLPEADLYI 249 + +++ FK EAD + Sbjct: 68 EKLKEFSDRV-----SLFKVSYREADFLL 91 >4YUX-A nrPDB Length = 304 Score = 35.2 bits (79), Expect = 0.046, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 49/151 (32%), Gaps = 15/151 (9%) Query: 115 RCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTA 174 W A ++R + Y +F + + + + +V + Sbjct: 25 DQWPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALDGCIQVTDYDEFVYHEV 84 Query: 175 FDLSVF------PLMCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTAKQHF----S 223 + + +GGG G + +E + + DI V+ +KQHF Sbjct: 85 LGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGTVEHCDLVDIDGEVMEQSKQHFPQISR 144 Query: 224 FQEEEQIDFQEGD--FFKDPLPE--ADLYIL 250 + + + GD F P+ D+ I+ Sbjct: 145 SLADPRATVRVGDGLAFVRQTPDNTYDVVII 175 >5EGS-A nrPDB Length = 376 Score = 34.8 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 24/152 (15%), Positives = 49/152 (32%), Gaps = 12/152 (7%) Query: 137 VPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP--LMCDLGGGAGALA 194 E Y + + + + + + + + + D+G G G L+ Sbjct: 39 RTKRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILS 98 Query: 195 KECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPE-ADLYILAR 252 C ++ + + A++ F E+++ G LPE D + Sbjct: 99 IFCAQAGAR-RVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEW 157 Query: 253 ----VLHDWADGKCSHLLERIYHTCKPGGGIL 280 +LH + S +L K GG +L Sbjct: 158 MGYGLLH---ESMLSSVLHARTKWLKEGGLLL 186 >2FCA-A nrPDB Length = 213 Score = 34.8 bits (78), Expect = 0.052, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 35/110 (31%), Gaps = 17/110 (15%) Query: 184 CDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEEEQIDF--QEGDFFKD 240 ++G G G P ++ V+ TA Q E + + + D D Sbjct: 43 IEVGTGKGQFISGMAKQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNIDADTLTD 102 Query: 241 PLPEADLYILARVLHDWADG-----------KCSHLLERIYHTCKPGGGI 279 ++ RV +++D SH L++ GG I Sbjct: 103 VFEPGEV---KRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSI 149 >1ZQ9-A nrPDB Length = 285 Score = 34.8 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 27/81 (33%) Query: 169 RSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE 228 S++ L ++ ++G G G + + + D V K+ Sbjct: 18 NSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVAS 77 Query: 229 QIDFQEGDFFKDPLPEADLYI 249 ++ GD K LP D + Sbjct: 78 KLQVLVGDVLKTDLPFFDTCV 98 >5MMS-A nrPDB Length = 408 Score = 34.4 bits (77), Expect = 0.074, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 33/114 (28%), Gaps = 18/114 (15%) Query: 163 VWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLY----PGCKITVFDIPEVVWTA 218 + +L D + L+ +G G PGC+I D + Sbjct: 232 HYDTTADEILQQCDGKLDMLVASVG--TGGTITGIARKLKEKCPGCRIIGVDPEGSILAE 289 Query: 219 KQHFS--FQEEEQIDFQEGDFFKDPLPEADLYILARVLHDW---ADGKCSHLLE 267 + + Q +++ DF +P + V+ W D + Sbjct: 290 PEELNQTEQTTYEVEGIGYDF----IPT---VLDRTVVDKWFKSNDEEAFTFAR 336 >4COO-A nrPDB Length = 563 Score = 34.4 bits (77), Expect = 0.074, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 33/114 (28%), Gaps = 18/114 (15%) Query: 163 VWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLY----PGCKITVFDIPEVVWTA 218 + +L D + L+ +G G PGC+I D + Sbjct: 254 HYDTTADEILQQCDGKLDMLVASVG--TGGTITGIARKLKEKCPGCRIIGVDPEGSILAE 311 Query: 219 KQHFS--FQEEEQIDFQEGDFFKDPLPEADLYILARVLHDW---ADGKCSHLLE 267 + + Q +++ DF +P + V+ W D + Sbjct: 312 PEELNQTEQTTYEVEGIGYDF----IPT---VLDRTVVDKWFKSNDEEAFTFAR 358 >1M54-A nrPDB Length = 363 Score = 34.4 bits (77), Expect = 0.074, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 33/114 (28%), Gaps = 18/114 (15%) Query: 163 VWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLY----PGCKITVFDIPEVVWTA 218 + +L D + L+ +G G PGC+I D + Sbjct: 189 HYDTTADEILQQCDGKLDMLVASVG--TGGTITGIARKLKEKCPGCRIIGVDPEGSILAE 246 Query: 219 KQHFS--FQEEEQIDFQEGDFFKDPLPEADLYILARVLHDW---ADGKCSHLLE 267 + + Q +++ DF +P + V+ W D + Sbjct: 247 PEELNQTEQTTYEVEGIGYDF----IPT---VLDRTVVDKWFKSNDEEAFTFAR 293 >2AVN-A nrPDB Length = 260 Score = 34.4 bits (77), Expect = 0.077, Method: Composition-based stats. Identities = 25/149 (16%), Positives = 50/149 (33%), Gaps = 23/149 (15%) Query: 139 AEELFTAIYRSEGERLQFMQALQEVWSVNGRSV---LTAFDLSVFPLMCDLGGGAGALAK 195 + E + I R+ + + W + R + L + + + DLGGG G + Sbjct: 17 SWEFYDRIARAYDSMYETPK-----WKLYHRLIGSFLEEYLKNPCR-VLDLGGGTGKWSL 70 Query: 196 ECMSLYPGCKITVFD-IPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYI-LA 251 G ++ + D E++ A++ + + E P P + + L Sbjct: 71 FLQER--GFEVVLVDPSKEMLEVARE------KGVKNVVEAKAEDLPFPSGAFEAVLALG 122 Query: 252 RVLHDWADGKCSHLLERIYHTCKPGGGIL 280 VL + I P G ++ Sbjct: 123 DVLSYVENKD--KAFSEIRRVLVPDGLLI 149 >5WMM-A nrPDB Length = 926 Score = 34.4 bits (77), Expect = 0.079, Method: Composition-based stats. Identities = 28/144 (19%), Positives = 45/144 (31%), Gaps = 12/144 (8%) Query: 147 YRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKI 206 ++S R + W SV+ + ++G G+G L Sbjct: 526 WKSSYTRDNIPLSEMRRWR---DSVVEEVRGLRARRILEIGVGSGLLLGPLAPEAEAYWG 582 Query: 207 TVFDIP-----EVVWTAKQHFSFQEEEQIDFQEGDFFKD-PLPEADLYILARVLHDWADG 260 T F +P EV + + D P+ D IL V+ + D Sbjct: 583 TDFSLPVIERLEVQVGTDPCLKEKVSLRCQH--ADVADGLPVKYFDTVILNSVVQYFPDA 640 Query: 261 KCS-HLLERIYHTCKPGGGILVIE 283 +L+ PGG ILV + Sbjct: 641 AYLSRVLDVALDRLAPGGRILVGD 664 >4KDR-A nrPDB Length = 223 Score = 34.0 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 9/103 (8%) Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQEEEQIDFQEGDFFK 239 + D+G G G LA+ G +T D+ E + AK H Q+D+ + + Sbjct: 64 KKVLDVGCGGGILAESMARE--GATVTGLDMGFEPLQVAKLHALESGI-QVDYVQETVEE 120 Query: 240 DPLPEA---DLYILARVLHDWADGKCSHLLERIYHTCKPGGGI 279 A D+ +L D + ++ KPGG + Sbjct: 121 HAAKHAGQYDVVTCMEMLEHVPDPQS--VVRACAQLVKPGGDV 161 >4KDC-A nrPDB Length = 246 Score = 34.0 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 39/103 (37%), Gaps = 9/103 (8%) Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQEEEQIDFQEGDFFK 239 + D+G G G LA+ G +T D+ E + AK H Q+D+ + + Sbjct: 64 KKVLDVGCGGGILAESMARE--GATVTGLDMGFEPLQVAKLHALESGI-QVDYVQETVEE 120 Query: 240 DPLPEA---DLYILARVLHDWADGKCSHLLERIYHTCKPGGGI 279 A D+ +L D + ++ KPGG + Sbjct: 121 HAAKHAGQYDVVTCMEMLEHVPDPQS--VVRACAQLVKPGGDV 161 >5LV5-A nrPDB Length = 403 Score = 34.0 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 18/149 (12%), Positives = 43/149 (28%), Gaps = 5/149 (3%) Query: 137 VPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFP--LMCDLGGGAGALA 194 E Y + + + + + + + + D+G G G L+ Sbjct: 66 RTKSERDQLYYECYSDVSVHEEMIADQVRTEAYRLGILKNWAALRGKTVLDVGAGTGILS 125 Query: 195 KECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDFFKDPLPE-ADLYILAR 252 C ++ + + A++ E+++ G LPE D + Sbjct: 126 IFCAQAGAR-RVYAVEASAIWQQAREVVRLNGLEDRVHVLPGPVETVELPERVDAIVSEW 184 Query: 253 VLHDWADGKCSHLLERIYHTCKPGGGILV 281 + + + GG+L+ Sbjct: 185 MGYGLLHESMLSSVLHARTKWLKEGGLLL 213 >5H02-A nrPDB Length = 283 Score = 34.0 bits (76), Expect = 0.099, Method: Composition-based stats. Identities = 21/134 (15%), Positives = 44/134 (32%), Gaps = 13/134 (9%) Query: 166 VNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFD-IPEVVWTAKQHFSF 224 G +++ + D+ G G + + G + D E++ A + Sbjct: 66 SEGDTIINILKERGVKKVLDVATGTGFNSVRLLQA--GFDVVSADGSAEMLVKAFDNARD 123 Query: 225 QEEEQIDFQEGD---FFKDPLPEADLYIL--ARVLHDWADGKCSHLLERIYHTCKPGGGI 279 + + D KD + D + H + +G L Y K G + Sbjct: 124 HGY-LMRTVQADWRWMNKDIHDKFDAIVCLGNSFTHLFDEGDRRKALAEFYALLKHDGVL 182 Query: 280 LV----IESLLDED 289 L+ +++LD+ Sbjct: 183 LLDQRNYDAILDDG 196 >4OBX-A nrPDB Length = 257 Score = 34.0 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 31/176 (17%), Positives = 66/176 (37%), Gaps = 32/176 (18%) Query: 183 MCDLGGGAGALAKECMSLYP------GCKITVFDI-PEVVWTAKQHFSFQEE----EQID 231 D+ GG+G +A + + + DI P+++ ++ Q + ++ Sbjct: 65 FIDVAGGSGDIAFGLLDHAESKFGDTESTMDIVDINPDMLKEGEKRAMEQGKYFKDPRVR 124 Query: 232 FQE--GDFFKDPLPEA-DLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE 288 F G+ ++ ++ D+Y ++ + ++ D + L Y KPGG +E E Sbjct: 125 FLVSNGEKLEEIDSDSKDIYTVSFGIRNFTDIQ--KGLNTAYRVLKPGGIFYCLEFSKIE 182 Query: 289 DRRGPLLTQLYSLNMLVQ--------------TEGQERTPTH--YHMLLSSAGFRD 328 + Q ++ + V E ER P + ++ AGF+ Sbjct: 183 NPLMDFAYQQWAKVLPVMGSMIANDYDSYQYLVESIERFPDQETFKSMIEKAGFKS 238 >2O06-A nrPDB Length = 304 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 42/132 (31%), Gaps = 18/132 (13%) Query: 162 EVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITV---FDIPEVVWTA 218 E + L + +GGG G + +E + +P + V D +V+ + Sbjct: 78 EFSYQEMIANLPLCSHPNPRKVLIIGGGDGGVLREVV-KHPSVESVVQCEID-EDVIQVS 135 Query: 219 KQHFSFQE----EEQIDFQEGDFFKDPLPEADLYILARVLHDWADG--KCSHLLERIY-- 270 K+ ++ GD F+ D ++ D +D L + Y Sbjct: 136 KKFLPGMAIGYSSSKLTLHVGDGFEFMKQNQDA--FDVIITDSSDPMGPAESLFKESYYQ 193 Query: 271 ---HTCKPGGGI 279 K G + Sbjct: 194 LMKTALKEDGVL 205 >3E23-A nrPDB Length = 211 Score = 33.6 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 43/136 (31%), Gaps = 18/136 (13%) Query: 150 EGERLQFMQALQEVWSVNGRSVLTAFDL----SVFPLMCDLGGGAGALAKECMSLYPGCK 205 + + L+F + ++ T + +LG GAG A+ ++ Sbjct: 10 DDDTLRFYRGNATAYAERQPRSATLTKFLGELPAGAKILELGCGAGYQAEAMLAA----- 64 Query: 206 ITVFD----IPEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGK 261 D PE+ A + + Q D + D L + Sbjct: 65 GFDVDATDGSPELAAEASRRLGRPVRTMLFHQ-----LDAIDAYDAVWAHACLLHVPRDE 119 Query: 262 CSHLLERIYHTCKPGG 277 + +L+ I+ KPGG Sbjct: 120 LADVLKLIWRALKPGG 135 >5BP7-A nrPDB Length = 271 Score = 33.6 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 54/142 (38%), Gaps = 10/142 (7%) Query: 171 VLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQ--EEE 228 + A L + DLG G+G + + G T D+ ++ + + + + Sbjct: 51 LGAALRLEPGTRVLDLGSGSGEMLCTWARDH-GIIGTGIDMSQLFTAQAKLRAEELGVAD 109 Query: 229 QIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLL-- 286 ++ F GD + + + A V W G + +E + + +PGG IL+ E Sbjct: 110 RVTFIHGDA-SGYVSDDKAGVAACVGATWIGGGVAGTIELLARSLRPGGIILIGEPYWRQ 168 Query: 287 ----DEDRRGPLLTQLYSLNML 304 ++ RG L ML Sbjct: 169 VPPTEDVARGCLANSTSDFLML 190 >5Y4R-A nrPDB Length = 294 Score = 33.3 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 43/250 (17%), Positives = 80/250 (32%), Gaps = 39/250 (15%) Query: 34 FDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLKLLKVETRGGKAFYRNTELSSDY 93 + L E G + + ++ G + ++ T ++R+T Sbjct: 55 LNKLMEQQGIKSLGELVQRIQTQRGGLREM--------VVDAMTTNETLWFRDTYPFEVL 106 Query: 94 LTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGER 153 V P ++K G R W A G+ Y + + E + Sbjct: 107 KQRVLPE----LIKANGGQRLRIWS---AACSSGQEPYSLSMAIDEFE--------KTNL 151 Query: 154 LQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPE 213 Q +Q V + S+LTA + + G G L+ E + Y K P Sbjct: 152 GQLKAGVQIVATDLSGSMLTAAKAGEYDTL---AMGRG-LSPERLQRYFDAKG-----PG 202 Query: 214 VVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA--DLYILARVLHDWADGKCSHLLERIYH 271 + +++F+ + D+ VL ++ +L RI+ Sbjct: 203 -----RWAVKPAIRSRVEFRALNLLDSYASLGKFDMVFCRNVLIYFSAEVKRDILLRIHG 257 Query: 272 TCKPGGGILV 281 T KPGG + + Sbjct: 258 TLKPGGYLFL 267 >1VQ1-A nrPDB Length = 294 Score = 32.9 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 21/155 (13%), Positives = 50/155 (32%), Gaps = 23/155 (14%) Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQE-EEQIDFQEGDF 237 + D+G G+GA+ + V A+++ ++ ++G+F Sbjct: 133 GIKTVADIGTGSGAIGVSVAKFSDAIVFATDVSSKAVEIARKNAERHGVSDRFFVRKGEF 192 Query: 238 FK---------------DPLPEADLYILARVLHD-----WADGKCSHLLERIYHTCKPGG 277 + P ++ ++ VL + + + G Sbjct: 193 LEPFKEKFASIEMILSNPPYVKSSAHLPKDVLFEPPEALFGGEDGLDFYREFFGRYDTSG 252 Query: 278 GILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQER 312 I+++E + ED+ L + L + G+ R Sbjct: 253 KIVLME--IGEDQVEELKKIVSDTVFLKDSAGKYR 285 >3VRD-B nrPDB Length = 401 Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 34/96 (35%), Gaps = 4/96 (4%) Query: 188 GGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEG-DFFKDPLPEAD 246 G G A ++ D V F++ ++ G D D + Sbjct: 61 GYDGLRAHGIQVVHDSALGIDPDKKLVKTAGGAEFAY---DRCVVAPGIDLLYDKIEGYS 117 Query: 247 LYILARVLHDWADGKCSHLLERIYHTCKPGGGILVI 282 + A++ H W G+ + LL R + GG +++ Sbjct: 118 EALAAKLPHAWKAGEQTALLRRQLESMDDGGVVIIA 153 >3SM3-A nrPDB Length = 235 Score = 32.9 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 17/109 (15%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 183 MCDLGGGAGALAKECMSLYPGCKITVFDIPEV--VWTAKQHFSF--QEEEQIDFQEGDFF 238 + D+G G+G ++ E S + + TA + + + +F+ + Sbjct: 34 ILDIGCGSGKISLELASKGYSVTGIDINSEAIRLAETAARSPGLNQKTGGKAEFKVENAS 93 Query: 239 KDPLPEA--DLYILARVLHDWADG-KCSHLLERIYHTCKPGGGILVIES 284 ++ D ++ L D + S +++ ++ KPG + ++E Sbjct: 94 SLSFHDSSFDFAVMQAFLTSVPDPKERSRIIKEVFRVLKPGAYLYLVEF 142 >4DZR-A nrPDB Length = 215 Score = 32.9 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 1/48 (2%) Query: 181 PLMCDLGGGAGALAKECMSLYPGCKITVFDIP-EVVWTAKQHFSFQEE 227 + D+G G+G +A PG +T D+ + + A+++ Sbjct: 32 TRVIDVGTGSGCIAVSIALACPGVSVTAVDLSMDALAVARRNAERFGA 79 >2GS9-A nrPDB Length = 211 Score = 32.5 bits (72), Expect = 0.25, Method: Composition-based stats. Identities = 18/105 (17%), Positives = 35/105 (33%), Gaps = 8/105 (7%) Query: 177 LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGD 236 L + ++G G G + YP K+ V ++ ++ + G+ Sbjct: 34 LPPGESLLEVGAGTGYWLRRL--PYPQ-KVGVEPSEAMLAVGRRRAPEATWVRA---WGE 87 Query: 237 FFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILV 281 P D+ +L L +L +PGG ++V Sbjct: 88 ALPFPGESFDVVLLFTTLEF--VEDVERVLLEARRVLRPGGALVV 130 >1DL5-A nrPDB Length = 317 Score = 32.5 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 47/130 (36%), Gaps = 18/130 (13%) Query: 161 QEVWSVNGRSVLTAF-DLSVFP---LMCDLGGGAGALAKECMSLYPGCKITVFDIP---E 213 +E + + S++ F + + ++GGG G MS G K V + + Sbjct: 53 EEYSTSSQPSLMALFMEWVGLDKGMRVLEIGGGTG-YNAAVMSRVVGEKGLVVSVEYSRK 111 Query: 214 VVWTAKQHFSFQEEEQIDFQEGDFF--KDPLPEADLYILARVLHDWADGKCSHLLERIYH 271 + AK++ E + F GD + D I V D + E + Sbjct: 112 ICEIAKRNVERLGIENVIFVCGDGYYGVPEFSPYD-VIFVTVGVD-------EVPETWFT 163 Query: 272 TCKPGGGILV 281 K GG ++V Sbjct: 164 QLKEGGRVIV 173 >1INL-A nrPDB Length = 296 Score = 32.5 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 18/132 (13%), Positives = 41/132 (31%), Gaps = 21/132 (15%) Query: 162 EVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTAKQ 220 E + + F + +GGG G +E + K + ++ V+ A++ Sbjct: 73 EFMYHEMLAHVPMFLHPNPKKVLIIGGGDGGTLREVLKHDSVEKAILCEVDGLVIEAARK 132 Query: 221 HFSFQ----EEEQIDFQ---EGDFFKDPLPEADLYILARVLHDWADGKC--------SHL 265 + ++ + + ++ + E D+ I+ D D Sbjct: 133 YLKQTSCGFDDPRAEIVIANGAEYVRKFKNEFDVIII-----DSTDPTAGQGGHLFTEEF 187 Query: 266 LERIYHTCKPGG 277 + Y K G Sbjct: 188 YQACYDALKEDG 199 >3HA5-A nrPDB Length = 318 Score = 32.5 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 21/177 (11%), Positives = 47/177 (26%), Gaps = 11/177 (6%) Query: 160 LQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPE-VVWTA 218 L+E L DL + D+G G G + + + + + + Sbjct: 71 LEEAQYAKVDLNLDKLDLKPGMTLLDIGCGWGTTMRRAVERFD-VNVIGLTLSKNQHARC 129 Query: 219 KQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGG 278 +Q + + + ++D D + + +R ++ G Sbjct: 130 EQVLASIDTNRSRQVLLQGWEDFAEPVDRIVSIEAFEHFGHENYDDFFKRCFNIMPADGR 189 Query: 279 ILVIESLLDEDRRGPLLTQLYSLNML---------VQTEGQERTPTHYHMLLSSAGF 326 + V S+ + S + G+ + AGF Sbjct: 190 MTVQSSVSYHPYEMAARGKKLSFETARFIKFIVTEIFPGGRLPSTEMMVEHGEKAGF 246 >5GJN-A nrPDB Length = 393 Score = 31.7 bits (70), Expect = 0.45, Method: Composition-based stats. Identities = 35/215 (16%), Positives = 64/215 (29%), Gaps = 40/215 (18%) Query: 32 GVFDLLAEAPGPLDVAAVAAGVRASAHGTELL-LDICVSLKLLKVETRGGKAFYRNTELS 90 GVF + P P ++ ++ AG+ + ++I L + G + Y N Sbjct: 45 GVFYAMKANPTP-EILSLLAGLGSHFDVASAGEMEILHELGV-----DGSQMIYANPVKD 98 Query: 91 SDYLTTVSPTSQCSMLKYMGRTSYRCWGHLAD--------AVREGR--NQYLETFGVPAE 140 + L + + + + AVR + FG P E Sbjct: 99 ARGLKAAADYNVR-RFTFDDPSEIDKMAKAVPGADVLVRIAVRNNKALVDLNTKFGAPVE 157 Query: 141 ELFTAIYRSEGERLQFM-------------QALQEVWSVNGRSVLTAFDLSVFPLMCDLG 187 E + ++ L M A +E V R A ++ + D+G Sbjct: 158 EALDLLKAAQDAGLHAMGICFHVGSQSLSTAAYEEALLVARRLFDEAEEMGMHLTDLDIG 217 Query: 188 GGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHF 222 GG P K D+ ++ + Sbjct: 218 GGF---------PVPDAKGLNVDLAAMMEAINKQI 243 >2HUN-A nrPDB Length = 336 Score = 31.7 bits (70), Expect = 0.48, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 19/55 (34%), Gaps = 4/55 (7%) Query: 186 LGGGAG----ALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGD 236 + GG G + + +P ++ D +++ + F +GD Sbjct: 8 VTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDDPRYTFVKGD 62 >3O4F-A nrPDB Length = 294 Score = 31.3 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 21/56 (37%), Gaps = 1/56 (1%) Query: 177 LSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDI-PEVVWTAKQHFSFQEEEQID 231 + +GGG GA+ +E IT+ +I VV +Q+ D Sbjct: 81 HGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYD 136 >1XJ5-A nrPDB Length = 334 Score = 31.3 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 42/116 (36%), Gaps = 23/116 (19%) Query: 181 PLMCDLGGGAGALAKECMSLYP--GCKITVFDIPEVVWTAKQHFSF----QEEEQIDFQE 234 + +GGG G + +E + D VV +KQ F E+ +++ Sbjct: 122 KKVLVIGGGDGGVLREVARHASIEQIDMCEIDK-MVVDVSKQFFPDVAIGYEDPRVNLVI 180 Query: 235 GD---FFKDPLPE-ADLYILARVLHDWADG--KCSHLLER-----IYHTCKPGGGI 279 GD F K+ D I+ D +D L E+ + +PGG + Sbjct: 181 GDGVAFLKNAAEGSYDAVIV-----DSSDPIGPAKELFEKPFFQSVARALRPGGVV 231 >4QPN-A nrPDB Length = 227 Score = 31.3 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 42/135 (31%), Gaps = 22/135 (16%) Query: 176 DLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEE------- 228 D + +LG G G + ++ G +T+ D+P + + + Sbjct: 74 DFRG-KKVIELGAGTGIV--GILAALQGGDVTITDLPLALEQIQGNVQANVPAGGQAQVR 130 Query: 229 ----QIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIES 284 ID D + AD+ L + LL + H C+P G I + Sbjct: 131 ALSWGIDHHVFPANYDLVLGADIVYL--------EPTFPLLLGTLQHLCRPHGTIYLASK 182 Query: 285 LLDEDRRGPLLTQLY 299 + E L Sbjct: 183 MRKEHGTESFFQHLL 197 >2VDV-E nrPDB Length = 246 Score = 30.9 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 22/161 (13%), Positives = 48/161 (29%), Gaps = 34/161 (21%) Query: 182 LMCDLGGGAGALAKECMSLYPG---------CKITVFDIPEVVWTAKQHFSFQEEEQIDF 232 + D+G G G L + +P ++T + ++ S + I+ Sbjct: 52 TIADIGCGFGGLMIDLSPAFPEDLILGMEIRVQVTNYVEDRIIALRNNTASKHGFQNINV 111 Query: 233 QEGD---FFKDPLPEADLYILARVLHDWADGKCSH-----------LLERIYHTCKPGGG 278 G+ F + + L+++ + D LL + K GG Sbjct: 112 LRGNAMKFLPNFFEKGQ---LSKMFFCFPDPHFKQRKHKARIITNTLLSEYAYVLKEGGV 168 Query: 279 ILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHM 319 + ++ D + + + L ER + Sbjct: 169 VY---TITDVKDLHEWMVKHLEEHPLF-----ERLSKEWEE 201 >1YZH-A nrPDB Length = 214 Score = 30.6 bits (67), Expect = 0.93, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 24/108 (22%), Gaps = 13/108 (12%) Query: 184 CDLGGGAGALAKECMSLYPGCKITVFD-IPEVVWTAKQHFSFQEEEQIDF--QEGDFFKD 240 ++G G GA P D V+ A I +G D Sbjct: 46 VEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD 105 Query: 241 PLPEA--DLYILARVLHDWADGKCSH-------LLERIYHTCKPGGGI 279 + D L W + L+ G I Sbjct: 106 YFEDGEIDRLYLNFS-DPWPKKRHEKRRLTYKTFLDTFKRILPENGEI 152 >1UIR-A nrPDB Length = 314 Score = 30.6 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 40/106 (37%), Gaps = 6/106 (5%) Query: 119 HLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLS 178 + + G+ + + F ++ + + + ++ ++LT Sbjct: 20 RMERVIASGKTPFQDYFLFESKGFGKVLILDKDVQSTERDEYIYHETLVHPAMLT---HP 76 Query: 179 VFPLMCDLGGGAGALAKECMSLYPGC-KITVFDIPE-VVWTAKQHF 222 + +GGG GA +E + +P K + DI +V AK+H Sbjct: 77 EPKRVLIVGGGEGATLREVL-KHPTVEKAVMVDIDGELVEVAKRHM 121 >5N1T-A nrPDB Length = 429 Score = 30.2 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 23/61 (37%), Gaps = 1/61 (1%) Query: 223 SFQEEEQIDFQEG-DFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILV 281 S +++ G D D + D + H W G+ + LL R GG +++ Sbjct: 129 SAIGYDRLVVSPGIDLRWDAVEGYDQAAQEAMPHAWRPGEQTLLLRRQLEAMSDGGVVVI 188 Query: 282 I 282 Sbjct: 189 A 189 >4FWE-A nrPDB Length = 796 Score = 30.2 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 38/126 (30%), Gaps = 17/126 (13%) Query: 158 QALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGC---KITVFDIPEV 214 + L E + +S + D S + G G A++ + P K + P + Sbjct: 558 EKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPL 617 Query: 215 VWTAKQHFSFQEEEQID--------------FQEGDFFKDPLPEADLYILARVLHDWADG 260 + + I+ Q DFF P A L V +D Sbjct: 618 SEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQ 677 Query: 261 KCSHLL 266 K +L Sbjct: 678 KKHSVL 683 >6GKZ-A nrPDB Length = 351 Score = 30.2 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 38/106 (35%), Gaps = 5/106 (4%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVF-DIPEVVWTAKQHFSFQEEEQIDFQEGDFFK- 239 + DLG G GAL Y C++T + ++ + ++ + D Sbjct: 126 SVLDLGCGQGALTLHVAQKYKNCRVTAVTNSVSQKEYIEEESRRRNLLNVEVKLADITTH 185 Query: 240 DPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESL 285 + D ++ + + + LL +I G +L +E + Sbjct: 186 EMAETYDRILVIELFEHMKNYEL--LLRKISEWISKDG-LLFLEHI 228 >4RX1-A nrPDB Length = 223 Score = 30.2 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 47/157 (29%), Gaps = 16/157 (10%) Query: 159 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPE----- 213 L + R+ L A ++ D+G G G +P D Sbjct: 4 QLGKASVTWTRADLEAKLAGHARVLIDVGTGDGRFVYRSAGAHPDTYCIGVDPAGERMRE 63 Query: 214 VVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSH--------L 265 V W A + + F LPE + + ++ + Sbjct: 64 VSWRASRKPARGGRPNALFVVAS--VQALPEELAGLAHTLTLNFPWASLLSALVLPEAPV 121 Query: 266 LERIYHTCKPGGGIL-VIESLLDEDRRGPLLTQLYSL 301 LE + +PGG ++ ++ + +DR L L Sbjct: 122 LEALRRLVRPGGELIALLNQSVFDDRPYAARLGLPEL 158 >3CJR-A nrPDB Length = 254 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 32/172 (18%), Positives = 49/172 (28%), Gaps = 7/172 (4%) Query: 120 LADAVREGRNQYLETFGV-PAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLS 178 L R+ + F V + + A L Sbjct: 60 LEAWRRDLKPALAPPFVVLAPWHTWEGAEIPLVIEPGMAFGTGHHETTRLALKALARHLR 119 Query: 179 VFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEGDFF 238 + DLG G+G L + G K DI +V + + + + F EG Sbjct: 120 PGDKVLDLGTGSGVL--AIAAEKLGGKALGVDIDPMVLPQAEANAKRNGVRPRFLEGS-L 176 Query: 239 KDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDEDR 290 + LP +L L+ + L R PGG L+ L D Sbjct: 177 EAALPFGPFDLLVANLY---AELHAALAPRYREALVPGGRALLTGILKDRAP 225 >2YXD-A nrPDB Length = 183 Score = 30.2 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 9/60 (15%), Positives = 23/60 (38%), Gaps = 1/60 (1%) Query: 176 DLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHFSFQEEEQIDFQEG 235 +L+ ++ D+G G+G + E + + + KQ+ + + +G Sbjct: 32 NLNKDDVVVDVGCGSGGMTVEIAKRCKFVYAIDY-LDGAIEVTKQNLAKFNIKNCQIIKG 90 >6GDG-A nrPDB Length = 479 Score = 29.8 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 38/106 (35%), Gaps = 4/106 (3%) Query: 220 QHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSH--LLERIYHTCKPGG 277 ++ FQ ++I D F + +AD IL +W+ +L+ I + G Sbjct: 50 ENLYFQGSDKIIHLTDDSFDTDVLKADGAILVDFWAEWSGPSKMIAPILDEIAD--EYQG 107 Query: 278 GILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSS 323 + V + +D++ + + L+ E T L Sbjct: 108 KLTVAKLNIDQNPGTAPKYGIRGIPTLLLFANGEVAATKVGALSKG 153 >2O3J-A nrPDB Length = 481 Score = 29.8 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 11/37 (29%), Gaps = 2/37 (5%) Query: 177 LSVFPLMCDLGGGA--GALAKECMSLYPGCKITVFDI 211 + +G G G P +TV D+ Sbjct: 6 FGKVSKVVCVGAGYVGGPTCAMIAHKCPHITVTVVDM 42 >3TMA-A nrPDB Length = 354 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 41/261 (15%), Positives = 76/261 (29%), Gaps = 29/261 (11%) Query: 46 VAAVAAGVRASAHGTELLLDICV-------SLKLLKVETRGGKAFYRNTELSSDYLTTVS 98 V A G+R + H + + +L+ + + + Sbjct: 63 VGEEALGLRLAHHLVLFRARLLLSREDPLGALERAALALPWPELEGAGSFRVEARREGEH 122 Query: 99 PTSQCSMLKYMGRTSYRCWGHLADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQ 158 P + + + +G +R +G D R ++ G A R R Sbjct: 123 PFTSPEVERRVGEALHRAYGVPVDLKRPAVRVRVDVRGEEAFLGVQLTERPLSRRFPKAA 182 Query: 159 ALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLY-PGCKITVFDI-PEVVW 216 + V +++L D + D G+G +A E S P + D+ + + Sbjct: 183 LRGSLTPVLAQALLRLADARPGMRVLDPFTGSGTIALEAASTLGPTSPVYAGDLDEKRLG 242 Query: 217 TAKQHFSFQEEEQIDFQEGDFFKDP--LPEADLYILA-----------RVLH-DWADGKC 262 A++ I F D P PE D + + H W Sbjct: 243 LAREAALASGLSWIRFLRADARHLPRFFPEVDRILANPPHGLRLGRKEGLFHLYWD---- 298 Query: 263 SHLLERIYHTCKPGGGILVIE 283 L PGG + ++ Sbjct: 299 --FLRGALALLPPGGRVALLT 317 >5KPG-A nrPDB Length = 397 Score = 29.0 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 14/28 (50%) Query: 182 LMCDLGGGAGALAKECMSLYPGCKITVF 209 + DLG G G+L Y GCK+T Sbjct: 171 SILDLGCGHGSLTLHVAQKYRGCKVTGI 198 >4JXJ-A nrPDB Length = 276 Score = 29.0 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 14/36 (38%) Query: 169 RSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGC 204 ++ A L + ++G G G L + + P Sbjct: 40 DKIVRASGLEENSNVLEIGPGTGGLTRSILHKNPKL 75 >4OKY-C nrPDB Length = 293 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 17/41 (41%) Query: 248 YILARVLHDWADGKCSHLLERIYHTCKPGGGILVIESLLDE 288 YI+ RV+H D + ++ G I + + L + Sbjct: 22 YIINRVVHTLDDPDIEFVCQQCIRKEGHLGKIYLADLLFPQ 62 >3MQ2-A nrPDB Length = 218 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 10/60 (16%), Positives = 20/60 (33%), Gaps = 4/60 (6%) Query: 151 GERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGGAGALAKECMSLYPGCKITVFD 210 R + +QE + + +D ++ D+G G G + P + D Sbjct: 3 SMRRVVGKRVQEFSDAEFEQLRSQYD----DVVLDVGTGDGKHPYKVARQNPSRLVVALD 58 >3UI2-A nrPDB Length = 244 Score = 27.9 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 31/86 (36%), Gaps = 2/86 (2%) Query: 1 MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAG-VRASAHG 59 + + + A G++ +V+ A ELG D+ E L +A ++ + G Sbjct: 103 LDHRDMRGGLTALHMAAGYVRPEVVEALVELG-ADIEVEDERGLTALELAREILKTTPKG 161 Query: 60 TELLLDICVSLKLLKVETRGGKAFYR 85 + + L+ + G Y Sbjct: 162 NPMQFGRRIGLEKVINVLEGQVFEYA 187 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.122 0.281 Lambda K H 0.267 0.0375 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,838,461 Number of Sequences: 36641 Number of extensions: 396012 Number of successful extensions: 1509 Number of sequences better than 10.0: 133 Number of HSP's better than 10.0 without gapping: 100 Number of HSP's successfully gapped in prelim test: 82 Number of HSP's that attempted gapping in prelim test: 1209 Number of HSP's gapped (non-prelim): 187 length of query: 345 length of database: 10,336,785 effective HSP length: 98 effective length of query: 247 effective length of database: 6,745,967 effective search space: 1666253849 effective search space used: 1666253849 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.5 bits)