BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46422 (212 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5A5K-A nrPDB 436 e-123 5F05-A nrPDB 252 7e-68 5F06-A nrPDB 207 3e-54 1AW9-A nrPDB 180 3e-46 5F07-A nrPDB 174 3e-44 5EY6-A nrPDB 163 4e-41 6F05-A nrPDB 155 1e-38 4RI7-A nrPDB 153 4e-38 1AXD-A nrPDB 151 2e-37 4MPF-A nrPDB 60 8e-10 2JL4-A nrPDB 60 9e-10 3IBH-A nrPDB 59 1e-09 3M3M-A nrPDB 56 1e-08 1G6W-A nrPDB 55 2e-08 1JLV-A nrPDB 55 2e-08 1E6B-A nrPDB 55 2e-08 2C3Q-A nrPDB 55 2e-08 4PNG-A nrPDB 55 2e-08 3LSZ-A nrPDB 55 2e-08 5ZWP-A nrPDB 55 3e-08 4PXO-A nrPDB 52 2e-07 3GX0-A nrPDB 51 3e-07 4YH2-A nrPDB 50 5e-07 3VWX-A nrPDB 50 6e-07 4QQ7-A nrPDB 50 7e-07 5D9W-A nrPDB 48 4e-06 1F2E-A nrPDB 48 4e-06 6JWK-A nrPDB 47 8e-06 1PN9-A nrPDB 46 9e-06 3TOT-A nrPDB 45 2e-05 4IKH-A nrPDB 45 3e-05 3M8N-A nrPDB 45 3e-05 2CZ2-A nrPDB 45 3e-05 5IQY-A nrPDB 45 3e-05 3MAK-A nrPDB 44 4e-05 2PMT-A nrPDB 44 6e-05 3UBL-A nrPDB 41 4e-04 3LFL-A nrPDB 41 4e-04 3C8E-A nrPDB 41 5e-04 1B8X-A nrPDB 40 5e-04 2IL3-A nrPDB 40 5e-04 2GDR-A nrPDB 40 5e-04 1DUG-A nrPDB 40 6e-04 3BBY-A nrPDB 40 6e-04 1BG5-A nrPDB 40 6e-04 4MDC-A nrPDB 40 8e-04 1N2A-A nrPDB 39 0.001 4MK3-A nrPDB 39 0.001 5F0G-A nrPDB 39 0.002 1FW1-A nrPDB 38 0.003 1TU7-A nrPDB 38 0.004 1VF1-A nrPDB 37 0.005 2GLR-A nrPDB 37 0.006 1GWC-A nrPDB 37 0.009 18GS-A nrPDB 36 0.010 3LG6-A nrPDB 36 0.010 5D73-A nrPDB 36 0.012 4IGJ-A nrPDB 35 0.027 2AAW-A nrPDB 34 0.039 2GSR-A nrPDB 34 0.040 1GSU-A nrPDB 34 0.049 1F3B-A nrPDB 34 0.052 3I6A-A nrPDB 33 0.068 4Q5Q-A nrPDB 33 0.069 1EV4-A nrPDB 33 0.072 5LCZ-A nrPDB 33 0.078 5AN1-A nrPDB 33 0.078 2VCT-A nrPDB 33 0.080 2VCV-A nrPDB 33 0.087 1B48-A nrPDB 33 0.10 1GUL-A nrPDB 33 0.12 1PL2-A nrPDB 33 0.12 3RBT-A nrPDB 32 0.15 1HNA-A nrPDB 31 0.36 4Q5F-A nrPDB 31 0.45 1ZL9-A nrPDB 30 0.56 3NIV-A nrPDB 30 1.0 1Y1X-A nrPDB 28 2.1 3GTU-B nrPDB 28 2.4 3H0K-A nrPDB 28 2.7 5E5B-A nrPDB 28 3.0 3VZI-A nrPDB 28 3.2 1T1U-A nrPDB 28 3.2 3KXO-A nrPDB 27 4.7 2ENX-A nrPDB 27 4.8 5Y9Z-A nrPDB 27 4.9 1K20-A nrPDB 27 5.0 5UJY-A nrPDB 27 6.1 4BSZ-B nrPDB 27 6.9 1G0A-B nrPDB 27 8.5 1FHJ-B nrPDB 27 9.0 >5A5K-A nrPDB Length = 212 Score = 436 bits (1122), Expect = e-123, Method: Compositional matrix adjust. Identities = 212/212 (100%), Positives = 212/212 (100%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED Sbjct: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF Sbjct: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL Sbjct: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ Sbjct: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 >5F05-A nrPDB Length = 212 Score = 252 bits (644), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 125/210 (59%), Positives = 154/210 (73%), Gaps = 4/210 (1%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A +K+ G S T+RVL L+EK ++FELV+V L GEHK+EP +S NPFGQVPA DG Sbjct: 1 APLKLHGSVLSTNTQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDG 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 DLKLFESRAI+QY+AH+Y ++GT L + YA + + +VE HQFDP ASKL +E Sbjct: 61 DLKLFESRAISQYVAHQYASKGTQLGAAGNG----YATILVWQEVESHQFDPSASKLVWE 116 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 Q+FK ++GL TD A+VAE E L KVLDVYEARL + KYLA ++FTL DLHH+P IQ LL Sbjct: 117 QVFKPVFGLPTDAALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHLPNIQALL 176 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKV 211 GTP+KKLF RP V+ WVA IT RPA KV Sbjct: 177 GTPSKKLFDSRPHVSAWVASITGRPAWGKV 206 >5F06-A nrPDB Length = 216 Score = 207 bits (527), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 96/208 (46%), Positives = 141/208 (67%), Gaps = 2/208 (0%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +K++G P S T RVL LHEKNLDFELV V+L GEHK+ PFL++NPFGQ+PA E+ DL Sbjct: 2 LKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 LFESRAIT YIA +++ G +L++ + N+ + A + + +VE H+++P + + F+ + Sbjct: 62 TLFESRAITSYIAEKFKGTGYDLIRHE--NLKEAASVKVWTEVESHRYNPAIAPIVFQFM 119 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 + G + D+ ++ + KL KVLD+YEA+L KYLAG+ ++L DLHH+P YL+ T Sbjct: 120 VAPLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYLMKT 179 Query: 184 PTKKLFTERPRVNEWVAEITKRPASEKV 211 P + ERP V W +I+ RPA +KV Sbjct: 180 PAASVVNERPHVKAWWEDISSRPAFKKV 207 >1AW9-A nrPDB Length = 216 Score = 180 bits (457), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 97/209 (46%), Positives = 126/209 (60%), Gaps = 4/209 (1%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A +K++G P S RV L+EK LDFE+V V+L G HK+ FL+ NPFGQ+PA DG Sbjct: 1 APLKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDG 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 D LFESRAI +YIA +Y ++GT+LL + A + + ++VE H F P AS L F+ Sbjct: 61 DEVLFESRAINRYIASKYASEGTDLLPATASA----AKLEVWLEVESHHFYPNASPLVFQ 116 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + + + G D AVV + +LAKVLDVYEA L KYLAG+ FTL D +H + YL Sbjct: 117 LLVRPLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHASYLLYLS 176 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEK 210 TP L RP V W I RPA +K Sbjct: 177 KTPKAGLVAARPHVKAWWEAIVARPAFQK 205 >5F07-A nrPDB Length = 213 Score = 174 bits (440), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 89/209 (42%), Positives = 130/209 (62%), Gaps = 4/209 (1%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +KV+G ++ +RV+ L EK ++F+LVHV+L GE K FL + PFGQVP EDGD Sbjct: 2 VKVYGPAVAVCPQRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDF 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 KLFESRAI +Y A +YE++G NLL + + A++ +++E H F+ + + F+ + Sbjct: 62 KLFESRAIIRYYAAKYEDRGPNLL---GNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVV 118 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG- 182 G D +V E KL KVLDVYE RL + KYLAG++FTL DL H+PA +YL+ Sbjct: 119 ILPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLPATRYLVNE 178 Query: 183 TPTKKLFTERPRVNEWVAEITKRPASEKV 211 L +R ++N W +I+ RPA +K+ Sbjct: 179 AGLGHLVKDRKKLNAWWEDISSRPAWKKL 207 >5EY6-A nrPDB Length = 217 Score = 163 bits (413), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 84/209 (40%), Positives = 122/209 (58%), Gaps = 3/209 (1%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +KV+G P S A RVL+ L EK++ F+++ V++ GEHKK +L PFGQVPAF+D + Sbjct: 4 VKVYGPPLSTAVSRVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDESI 63 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 LFESR+I +Y+ +Y ++G L N + A + ++ E F P + L F+ Sbjct: 64 SLFESRSICRYVCEKYADRGDKGLY--GTNPLERASIDQWVEAEGQSFGPSSGALVFQLA 121 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 F + D+ V+ + E KL KVLD+YE RL E ++LAG+ FT DL H+P YL+ Sbjct: 122 FAPRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYLVNA 181 Query: 184 PTKK-LFTERPRVNEWVAEITKRPASEKV 211 K LFT R V W EI+ R + +KV Sbjct: 182 TDKGHLFTSRENVGRWWNEISDRESWKKV 210 >6F05-A nrPDB Length = 215 Score = 155 bits (392), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 84/205 (40%), Positives = 121/205 (59%), Gaps = 5/205 (2%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +KV+G P + +R L+ L EK + FE + V+L GEHK+ +L+ PFG VPA DGD Sbjct: 3 LKVYG-PHFASPKRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDY 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 K+FESRA+ +Y+A +Y +QG +LL K + + + VE + P L + Sbjct: 62 KIFESRAVMRYVAEKYRSQGPDLL---GKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIM 118 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 F S+ G +DE ++ E E KLA VLDVYEA L + KYLAG+ +L DL H+P YL+G Sbjct: 119 FASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGP 178 Query: 184 PTKK-LFTERPRVNEWVAEITKRPA 207 K + +R V+ W +I+ RPA Sbjct: 179 IGKAYMIKDRKHVSAWWDDISSRPA 203 >4RI7-A nrPDB Length = 215 Score = 153 bits (387), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 84/213 (39%), Positives = 124/213 (58%), Gaps = 14/213 (6%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 + ++G P A RVL L EK++ F L+ ++L GE KK +L PFGQVPAF+D + Sbjct: 5 VTIYGPPLCTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDESI 64 Query: 64 KLFESRAITQYIAHRYENQGT-NLLQTD---SKNISQYAIMAIGMQVEDHQFDPVASKLA 119 LFESRAI +YI +Y ++G +L TD NI Q+ ++ + F P + L Sbjct: 65 TLFESRAICRYICDKYADKGNKSLYGTDILSKANIDQW------VETDGQTFGPPSGDLV 118 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 + +F S+ DEA++ + KLAKVLD+YE +L + ++LAG+ F+ DL H+P Y Sbjct: 119 HDLLFSSV---PVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDY 175 Query: 180 LLGTPTKK-LFTERPRVNEWVAEITKRPASEKV 211 L+ + K LFT R VN W EI+ R + +KV Sbjct: 176 LVNSTDKGYLFTSRKNVNRWWTEISNRESWKKV 208 >1AXD-A nrPDB Length = 209 Score = 151 bits (382), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 82/210 (39%), Positives = 121/210 (57%), Gaps = 5/210 (2%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A +K++G S R AL E D+E+V + EHK L RNPFGQVPA +DG Sbjct: 1 APMKLYGAVMSWNLTRCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDG 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 DL LFESRAI +Y A + + + LL+ N+ + A++ + ++VE +Q+ + + F+ Sbjct: 61 DLYLFESRAICKYAARKNKPE---LLR--EGNLEEAAMVDVWIEVEANQYTAALNPILFQ 115 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + + G TTD+ VV E KL KVL+VYEARL + KYLAG+ +L DL+H+ L Sbjct: 116 VLISPMLGGTTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLF 175 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKV 211 TP + P V W + + +RP+ +KV Sbjct: 176 ATPYASVLDAYPHVKAWWSGLMERPSVQKV 205 >4MPF-A nrPDB Length = 266 Score = 59.7 bits (143), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 53/214 (24%), Positives = 89/214 (41%), Gaps = 12/214 (5%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 G+++F S +R V I + + EL V+L G+HK + FL N G++P +DGD Sbjct: 24 GLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGD 83 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA--- 119 L ES AI Y++ +Y+ D S A + D + Sbjct: 84 FILTESSAILIYLSCKYQT-------PDHWYPSDLQARARVHEYLGWHADCIRGTFGIPL 136 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEAR-LKEFKYLAGETFTLTDLHHIPAIQ 178 + Q+ + G+ + V + + L E + L + +LAG+ TL DL + + Sbjct: 137 WVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELM 196 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 + +LF RPR+ W + +E Q Sbjct: 197 QPVAL-GYELFEGRPRLAAWRGRVEAFLGAELCQ 229 >2JL4-A nrPDB Length = 213 Score = 59.7 bits (143), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 50/180 (27%), Positives = 86/180 (47%), Gaps = 13/180 (7%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +K++ S + R+ IAL+ K + +E + V L EH K+ F + NP VPA + G Sbjct: 2 MKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGAQ 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 L +S AI +++ +Y LL D+ + +A + + H P+ ++ E + Sbjct: 62 VLIQSPAIIEWLEEQYPTPA--LLPADADGRQRVRALAAIVGCDIH---PINNRRILEYL 116 Query: 124 FKSIYGLTTDEAVV-AEEEAKLAKVLDVYEARL----KEFKYLAGETFTLTDLHHIPAIQ 178 K+ DEA + A ++ D YEA L K +Y G+T TL D + +P ++ Sbjct: 117 RKT---FGADEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVE 173 >3IBH-A nrPDB Length = 233 Score = 59.3 bits (142), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 64/218 (29%), Positives = 100/218 (45%), Gaps = 25/218 (11%) Query: 6 VFGHPASIATRRVLIALHEKNL--DFELVHVELKDGEHKKEPFLSRNPFGQVPAFE--DG 61 ++ PA RV IAL EKN+ + V + L GEHKK FL++N G VP E DG Sbjct: 21 IYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLELDDG 80 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L + E AIT+YI GT L T + + I + + E DPV+ + F Sbjct: 81 TL-IAECTAITEYIDAL---DGTPTL-TGKTPLEKGVIHMMNKRAELELLDPVS--VYFH 133 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKV------LDVYEARLKEFKYLAGETFTLTDLHHIP 175 + GL + + +E L + + ++ L+E Y+AG++F++ D I Sbjct: 134 H---ATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMAD---IT 187 Query: 176 AIQYLLGTPTKKLFT--ERPRVNEWVAEITKRPASEKV 211 I L+ KL E + W + +RP+ +K+ Sbjct: 188 VIAGLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKL 225 >3M3M-A nrPDB Length = 210 Score = 55.8 bits (133), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/177 (28%), Positives = 85/177 (48%), Gaps = 21/177 (11%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPA--F 58 M+ KV+G S ++ + L+ L +E V++ G+ + E FL++NP G++P Sbjct: 1 MSLYKVYGDYRSGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLEL 60 Query: 59 EDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKL 118 EDG L+ES AI ++A G+ L ++ + +Q E + +P + Sbjct: 61 EDGTC-LWESNAILNFLA-----DGSQFLPSEPRLRTQVLQWQF---FEQYSHEPYIAVA 111 Query: 119 AFEQIFKSIYGLTTDEAVVAEEEAKL----AKVLDVYEARLKEFKYLAGETFTLTDL 171 F Q+++ GL + EE KL K LDV E +L YL GE +++ D+ Sbjct: 112 RFIQLYE---GLPEER---REEYLKLHKRGYKALDVMEKQLSRTPYLVGEHYSIADI 162 >1G6W-A nrPDB Length = 261 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 60/242 (24%), Positives = 102/242 (42%), Gaps = 41/242 (16%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 + G +F H ++ +V I L E + + ++ GEH+ F+S NP +VPA D Sbjct: 18 LEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALID 77 Query: 61 ---GDLKLFESRAITQYIAHRYENQ-GTNLLQTDSK------------NISQYAIMAIGM 104 +L ++ES AI ++ ++Y + G LL +D S +A M IG Sbjct: 78 HGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPM-IGQ 136 Query: 105 QVEDHQFDPVASKLAFEQI---FKSIYGLTTDEAVVAEEEAKLAKVLD------------ 149 + F A E+ + +YG+ E +AE L LD Sbjct: 137 ALHFRYFHSQKIASAVERYTDEVRRVYGVV--EMALAERREALVMELDTENAAAYSAGTT 194 Query: 150 -VYEARLKEFK-YLAGETFTLTDLHHIPAIQYL--LGTPTKKLFTERPRVNEWVAEITKR 205 + ++R ++ +L G+ T+ DL +P + +G K E P V +W + +R Sbjct: 195 PMSQSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIK---IEFPEVYKWTKHMMRR 251 Query: 206 PA 207 PA Sbjct: 252 PA 253 >1JLV-A nrPDB Length = 209 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 45/165 (27%), Positives = 67/165 (40%), Gaps = 17/165 (10%) Query: 10 PASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESR 69 P S R V + ++ L L GEH K FL NP +P D L+ESR Sbjct: 7 PGSAPCRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLVDNGFALWESR 66 Query: 70 AITQYIAHRYENQGTNLLQTDSKN---ISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKS 126 AI Y+A +Y + L D + ++Q +G + + + QIF Sbjct: 67 AICTYLAEKY-GKDDKLYPKDPQKRAVVNQRLYFDMGTLYQRF------ADYYYPQIF-- 117 Query: 127 IYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 + AE E K+ +D L KY+AG++ T+ DL Sbjct: 118 -----AKQPANAENEKKMKDAVDFLNTFLDGHKYVAGDSLTIADL 157 >1E6B-A nrPDB Length = 221 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 4/109 (3%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +K++ + S RV IAL K LD+E + V L G+ F NP G VPA DGD+ Sbjct: 9 LKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDGDV 68 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTD-SKNISQYAIMAIGMQ-VEDHQ 110 + +S AI Y+ +Y LL D K Y M+I + ++ HQ Sbjct: 69 VINDSFAIIMYLDEKYPEPP--LLPRDLHKRAVNYQAMSIVLSGIQPHQ 115 >2C3Q-A nrPDB Length = 247 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 G++++ S R V I + ++ FEL V+L G+H + F NP +VPA +DGD Sbjct: 9 GLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGD 68 Query: 63 LKLFESRAITQYIAHRY---ENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 L ES AI Y+ +Y + LQ ++ A ++ L Sbjct: 69 FTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRRS------CLRALW 122 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK-YLAGETFTLTDLHHIPAIQ 178 + +F G +A A+L L + E + + K +L G +L DL I + Sbjct: 123 HKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELM 182 Query: 179 YLLGTPTKKLFTERPRVNEW 198 + +G ++F RP++ W Sbjct: 183 HPVGAGC-QVFEGRPKLATW 201 >4PNG-A nrPDB Length = 229 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 16/215 (7%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++G AS R V + L + +E V V + E+ E FL +NP VP ED Sbjct: 7 MPKLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLED 66 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDS---KNISQYAIMAIGMQVEDHQFDPVASK 117 +++S AI Y+ +Y +TDS K++ Q A++ + E V Sbjct: 67 DGHYIWDSHAIIAYLVSKYG-------KTDSLYPKDLLQRAVVDQRLHFESG----VIFA 115 Query: 118 LAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAI 177 A I K ++ + E + +V D E L Y+AG T+ D I + Sbjct: 116 NALRSITKPLFA-GKQTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTV 174 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 L K T+ PR+ W + K P E+ Sbjct: 175 SS-LEVFVKVDTTKYPRIAAWFKRLQKLPYYEEAN 208 >3LSZ-A nrPDB Length = 225 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 62/217 (28%), Positives = 93/217 (42%), Gaps = 25/217 (11%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHV-ELKDGEHKKEP----------FLSRNPF 52 +K++G S A+R + + L E +L FE V V + H P +L+ NP Sbjct: 3 LKIYGVYRSRASRPLWL-LAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNPL 61 Query: 53 GQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFD 112 GQ+P E+ L L ES AIT +IA QG Q ++ + A+M + Sbjct: 62 GQIPCLEEEGLILTESLAITLHIAR---TQGG---QLGPRSEPEDALMVSWSLFAATAVE 115 Query: 113 PVASKLAFEQIFKSIYGLTTDE--AVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTD 170 P A ++ Q+ + G T+ E A +A +L + L E YL G FT+ D Sbjct: 116 PPALEI---QLIQRSGGGTSPEGQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVAD 172 Query: 171 LHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPA 207 L+ ++Y G L P V W+ RPA Sbjct: 173 LNLAETLRY--GQAHPALLEPFPAVAAWLDRCQSRPA 207 >5ZWP-A nrPDB Length = 208 Score = 54.7 bits (130), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 52/207 (25%), Positives = 83/207 (40%), Gaps = 26/207 (12%) Query: 10 PASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESR 69 P S R VL+ ++ + L+ GEH K FL NP +P DGD L+ESR Sbjct: 7 PGSAPCRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGDFALWESR 66 Query: 70 AITQYIAHRYENQGTNLLQTDSKN--ISQYAIMAIGM---QVEDHQFDPVASKL-AFEQI 123 AI Y+ +Y + + K I+Q +G D+ + + +K A ++ Sbjct: 67 AIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKSFADYYYPQIFAKAPADPEL 126 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 FK K+ D LK +Y AG++ T+ DL + ++ Sbjct: 127 FK-----------------KIETAFDFLNTFLKGHEYAAGDSLTVADLALLASVSTFEVA 169 Query: 184 PTKKLFTERPRVNEWVAEI-TKRPASE 209 ++ P V +W A + T P E Sbjct: 170 SFD--ISKYPNVAKWYANLKTVAPGWE 194 >4PXO-A nrPDB Length = 238 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 31/73 (42%), Positives = 44/73 (60%), Gaps = 1/73 (1%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD- 62 +K++G+ S A RV IAL+ K + +E V ++L G+ K FL+ NP G VPA DGD Sbjct: 24 VKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALFDGDG 83 Query: 63 LKLFESRAITQYI 75 L +S AI Y+ Sbjct: 84 PPLTQSLAILDYL 96 >3GX0-A nrPDB Length = 215 Score = 51.2 bits (121), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 49/205 (23%), Positives = 82/205 (40%), Gaps = 32/205 (15%) Query: 17 RVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD-------LKLFESR 69 ++ + L E LD+ L+ V+L G + FL +P ++PA D L LFES Sbjct: 14 KITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHSPADGGEPLSLFESG 73 Query: 70 AITQYIAHRYENQGTNLLQTDSKNIS--QYAIMAIG----MQVEDHQFDPVASKLAFEQI 123 AI Y+A E G L + + Q+ +G M ++H F+ A + Sbjct: 74 AILLYLA---EKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQ------ 124 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 T + + + ++ V RL+ +L GE +++ D+ P + T Sbjct: 125 --------TIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWPWVNAW--T 174 Query: 184 PTKKLFTERPRVNEWVAEITKRPAS 208 + P V W I RPA+ Sbjct: 175 RQRIDLAMYPAVKNWHERIRSRPAT 199 >4YH2-A nrPDB Length = 222 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 51/223 (22%), Positives = 91/223 (40%), Gaps = 36/223 (16%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++G S R V + L NL +E V+V++ +L +NP VP ED Sbjct: 1 MVKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLED 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +++S AI Y+ +Y + + Y + V D + S + F Sbjct: 61 DGHYIWDSHAIIAYLVSKYADSD-----------ALYPKDPLKRAVVDQRLH-FESGVVF 108 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAK--------VLDVYEARLKEFKYLAGETFTLTDLH 172 +SI ++V+ + + K+ K + D E LK Y+AG T+ D Sbjct: 109 ANGIRSI-----SKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFS 163 Query: 173 HIPAIQYL-----LGTPTKKLFTERPRVNEWVAEITKRPASEK 210 + ++ L L T T+ PR+ W+ ++ + P E+ Sbjct: 164 LVSSVASLEAFVALDT------TKYPRIGAWIKKLEQLPYYEE 200 >3VWX-A nrPDB Length = 222 Score = 50.4 bits (119), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 49/231 (21%), Positives = 82/231 (35%), Gaps = 52/231 (22%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++G S R L+ L NL FE V L EH E +L +NP VP E+ Sbjct: 1 MGKLVLYGIDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEE 60 Query: 61 GDLKLFESRAITQYIAHRYEN---------------------QGTNLLQTDSKNISQYAI 99 +++S AI Y+ +Y + L Q +NI+ Sbjct: 61 DGHLIWDSHAIMAYLVSKYGKDDSLYPKDLLKRAVVDQRMYFEAGVLFQGGLRNITAPLF 120 Query: 100 MAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK 159 Q+ HQ D + F + F LK K Sbjct: 121 FRNQTQIPQHQIDSIVESYGFLESF------------------------------LKNNK 150 Query: 160 YLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 Y+AG+ T+ D + ++ L+ ++ P+++ W+ + P E+ Sbjct: 151 YMAGDHLTIADFSIVTSVTSLVAFAEIDQ-SKFPKLSAWLKSLQSLPFYEE 200 >4QQ7-A nrPDB Length = 207 Score = 50.1 bits (118), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 35/176 (19%) Query: 15 TRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQY 74 ++R + L EK +DFE+ V+L + K E NP+GQVP + DL L+ES I +Y Sbjct: 17 SQRCRLVLFEKGMDFEIRDVDLFN---KPEDISVMNPYGQVPILVERDLILYESNIINEY 73 Query: 75 IAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDE 134 I R+ + L+ D ++ + + + +++F + L ++ Sbjct: 74 IDERFPH--PQLMPADPVQRARARLFLLNFE---------------KELFVHVSTLENEK 116 Query: 135 AVVAE---EEAKLAKVLDVYEARLKEF-------KYLAGETFTLTDLHHIPAIQYL 180 AE E+A+LA RL + KY+ GE F++ D+ P + L Sbjct: 117 GKAAEKNHEKARLA-----IRDRLTQLAPIFVKNKYMLGEEFSMLDVAIAPLLWRL 167 >5D9W-A nrPDB Length = 230 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 8/77 (10%) Query: 8 GHPASIA----TRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 GHP ++ ++RVL+ L EK + +E+ +L D ++K + FL +P G+VP F GD Sbjct: 29 GHPDTLGDSPFSQRVLLTLEEKKVPYEM---KLIDVQNKPDWFLKISPEGKVPVFNGGDG 85 Query: 64 KLF-ESRAITQYIAHRY 79 K +S ITQ I +Y Sbjct: 86 KWIPDSDVITQVIEEKY 102 >1F2E-A nrPDB Length = 201 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 55/194 (28%), Positives = 84/194 (43%), Gaps = 25/194 (12%) Query: 20 IALHEKNLDFELVHVELK-DGEHKKEPFLSRNPFGQVPAFE-DGDLKLFESRAITQYIAH 77 IAL E DFE V V+L E FL+ NP G+VPA D L E+ AI YIA Sbjct: 16 IALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDSGETLTENPAILLYIAD 75 Query: 78 RYENQGTNLLQTDSKNISQYAIMA--IGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEA 135 + G L ++ +Y +++ + E H+ AF +F T+DEA Sbjct: 76 QNPASG---LAPAEGSLDRYRLLSRLSFLGSEFHK--------AFVPLFAPA---TSDEA 121 Query: 136 VVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPT--KKLFTERP 193 A E+ + L + L + AG F++ D++ + +LG P P Sbjct: 122 KAAAAES-VKNHLAALDKELAGRDHYAGNAFSVADIY----LYVMLGWPAYVGIDMAAYP 176 Query: 194 RVNEWVAEITKRPA 207 + + +I +RPA Sbjct: 177 ALGAYAGKIAQRPA 190 >6JWK-A nrPDB Length = 222 Score = 46.6 bits (109), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 26/65 (40%), Positives = 36/65 (55%), Gaps = 1/65 (1%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLF-ESRA 70 S + RV IAL K LD+++V V L+ GE + RNP G +P D D + F +S A Sbjct: 9 SSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADGRRFSQSLA 68 Query: 71 ITQYI 75 I Y+ Sbjct: 69 IIDYL 73 >1PN9-A nrPDB Length = 209 Score = 46.2 bits (108), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 25/70 (35%), Positives = 33/70 (47%) Query: 10 PASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESR 69 P S R V + ++ L +L GEH K FL NP +P D L+ESR Sbjct: 7 PGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLVDNGFALWESR 66 Query: 70 AITQYIAHRY 79 AI Y+A +Y Sbjct: 67 AIQIYLAEKY 76 >3TOT-A nrPDB Length = 226 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 51/215 (23%), Positives = 88/215 (40%), Gaps = 31/215 (14%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAF--EDG 61 +K+ G AS TR+V + L EK +D++ V ++ + + + F NP G+VP +DG Sbjct: 3 MKLIGSHASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQF---NPLGKVPCLVMDDG 59 Query: 62 DLKLFESRAITQY------IAHRYENQGTNLLQTDSKNISQYAIM--AIGMQVEDHQFDP 113 LF+SR I +Y +A G ++ ++ A+ ++VE Q P Sbjct: 60 G-ALFDSRVIAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTP 118 Query: 114 VASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHH 173 EQ E+ + + K+ + L L + + G TL D+ Sbjct: 119 -------EQ---------RSESWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAV 162 Query: 174 IPAIQYL-LGTPTKKLFTERPRVNEWVAEITKRPA 207 A+ YL P + + + I KRP+ Sbjct: 163 GCALAYLDFRQPQVDWREQHANLAAFYTRIEKRPS 197 >4IKH-A nrPDB Length = 244 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 48/175 (27%), Positives = 76/175 (43%), Gaps = 21/175 (12%) Query: 17 RVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED----GD--LKLFESRA 70 +V I L E L +E V + + FLS +P ++PA D GD L LFES A Sbjct: 35 KVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAILDPHGPGDQPLALFESGA 94 Query: 71 ITQYIAHRYENQGTNLLQTDSKNIS--QYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIY 128 I Y+A + G L Q + Q+ + +G P+ ++ F F Sbjct: 95 ILIYLADK---SGQLLAQESAARYETIQWLMFQMG------GIGPMFGQVGF---FNKFA 142 Query: 129 GLTTDEAVVAEEEAKLAK-VLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 G ++ E AK +L V + L +++ GE +T+ D+ P I+ L+G Sbjct: 143 GREYEDKRPLERYVNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPWIRNLIG 197 >3M8N-A nrPDB Length = 225 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 58/218 (26%), Positives = 86/218 (39%), Gaps = 32/218 (14%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M+ K++ S + +V +AL + + V V++ GE + FL++NP GQVP E Sbjct: 1 MSLYKLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLET 60 Query: 61 GDLK-LFESRAITQYIAHRYENQGTNL---LQTDSKNISQYAIMAIGMQVEDHQFDP-VA 115 + L ES AI Y+A GT+L + D Q+ M E H +P + Sbjct: 61 APGRYLAESNAILWYLA-----VGTSLAPDTRMDRAEALQW------MFFEQHALEPNIG 109 Query: 116 SKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL---- 171 S + + K L T E A L V E LK Y A T+ D+ Sbjct: 110 SAYFWLCLVKGGRDLQTHALEDWLERGYAA--LQVMENHLKTNDYFAAGQLTIADIALYG 167 Query: 172 --HHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPA 207 H + L T P VN W+ + + P Sbjct: 168 YTHVADQCDFDLST--------FPAVNAWLRRVEQTPG 197 >2CZ2-A nrPDB Length = 223 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 2/66 (3%) Query: 12 SIATRRVLIALHEKNLDFELVHVEL-KDGEHK-KEPFLSRNPFGQVPAFEDGDLKLFESR 69 S + RV IAL K +D+E+V + L KDG + E F + NP QVPA + + + +S Sbjct: 21 SSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGITIVQSL 80 Query: 70 AITQYI 75 AI +Y+ Sbjct: 81 AIMEYL 86 >5IQY-A nrPDB Length = 216 Score = 44.7 bits (104), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 26/66 (39%), Positives = 39/66 (59%), Gaps = 4/66 (6%) Query: 15 TRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLF-ESRAITQ 73 ++RVL+ L EK + +E+ V+L + K E FL +P G+VP F GD K +S ITQ Sbjct: 26 SQRVLLTLEEKKITYEMKLVDLSN---KPEWFLKISPEGKVPVFNSGDGKWIADSDVITQ 82 Query: 74 YIAHRY 79 I ++ Sbjct: 83 VIEEKF 88 >3MAK-A nrPDB Length = 209 Score = 44.3 bits (103), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 33/70 (47%) Query: 10 PASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESR 69 P S R V++ ++ + L+ GEH K FL NP +P D L+ESR Sbjct: 8 PGSSPCRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDNGFALWESR 67 Query: 70 AITQYIAHRY 79 AI Y+ +Y Sbjct: 68 AIQVYLVEKY 77 >2PMT-A nrPDB Length = 203 Score = 43.5 bits (101), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 56/208 (26%), Positives = 95/208 (45%), Gaps = 24/208 (11%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVEL--KDGEHKKEPFLSRNPFGQVPA--FE 59 +K++ P S + I L E LDF + ++L K E K+ FL+ NP GQVP + Sbjct: 1 MKLYYTPGSCSLSP-HIVLRETGLDFSIERIDLRTKKTESGKD-FLAINPKGQVPVLQLD 58 Query: 60 DGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 +GD+ L E AI QY+A L+ D I+ + Q+E F +AS++ Sbjct: 59 NGDI-LTEGVAIVQYLAD---------LKPDRNLIAPPKALERYHQIEWLNF--LASEV- 105 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 + + ++ T E+ + + KL L + K + G+ FT+ D + Q+ Sbjct: 106 -HKGYSPLFSSDTPESYLPVVKNKLKSKFVYINDVLSKQKCVCGDHFTVADAYLFTLSQW 164 Query: 180 LLGTPTKKL-FTERPRVNEWVAEITKRP 206 P L T+ + +++A I +RP Sbjct: 165 ---APHVALDLTDLSHLQDYLARIAQRP 189 >3UBL-A nrPDB Length = 242 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 43/174 (24%), Positives = 75/174 (43%), Gaps = 21/174 (12%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE- 59 M IK+ G S +V + + EK L++E + + ++E FL +P G++P E Sbjct: 1 MVMIKLHGASISNYVNKVKLGILEKGLEYEQIRI----APSQEEDFLKISPMGKIPVLEM 56 Query: 60 DGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 DG +FES AI +++ + Q L+ D ++ + I +E + P Sbjct: 57 DGKF-IFESGAILEFLDTIFP-QTPKLIPEDPWEAAR--VREISTIIETYLDIPA----- 107 Query: 120 FEQIFKSIY--GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 + IY +V E + L K + + ++ Y+AG FTL D Sbjct: 108 -----RRIYLPAAKVSPEIVEEVHSTLVKGIKALQRVVRFSPYIAGNVFTLADC 156 >3LFL-A nrPDB Length = 240 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 48/207 (23%), Positives = 83/207 (40%), Gaps = 21/207 (10%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 I+++ R + L K + E++++ LK+ K E F +NPFG VP E+ Sbjct: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKN---KPEWFFKKNPFGLVPVLENS 78 Query: 62 DLKLFESRAIT-QYIAHRYENQGTNLLQTDS-KNISQYAIMAIGMQVEDHQFDPVASKLA 119 +L AIT +Y+ Y G LL D + Q I+ + +V V S + Sbjct: 79 QGQLIYESAITCEYLDEAY--PGKKLLPDDPYEKACQKMILELFSKVPSL----VGSFIR 132 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 + D A + EE K L+V K+ + G + ++ D P + Sbjct: 133 SQN--------KEDYAGLKEEFRKEFTKLEVLTN--KKTTFFGGNSISMIDYLIWPWFER 182 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRP 206 L + P++ W+A + + P Sbjct: 183 LEAMKLNECVDHTPKLKLWMAAMKEDP 209 >3C8E-A nrPDB Length = 288 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 48/210 (22%), Positives = 90/210 (42%), Gaps = 38/210 (18%) Query: 19 LIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED----GDLKLFESRAITQY 74 L+AL +++ + + DG+ F+ NP ++PA D +++FES +I Y Sbjct: 65 LLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLY 124 Query: 75 IAHRYENQGTNLLQ-----TDSKN----ISQYAIMAIGMQVEDHQFDPVASKLAFEQIFK 125 +A ++ G L Q T++ N + A G + + PV + A + Sbjct: 125 LAEKF---GYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFGHFYHYAPVKIEYAINRF-- 179 Query: 126 SIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL--GT 183 EAK ++LDV + +L + K++AG+ +T+ D+ P ++ G Sbjct: 180 -------------TMEAK--RLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGV 224 Query: 184 PTKKLFTER---PRVNEWVAEITKRPASEK 210 F + V W E+ +RPA ++ Sbjct: 225 YDAAEFLDAGSYKHVQRWAKEVGERPAVKR 254 >1B8X-A nrPDB Length = 280 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 18/130 (13%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P + DGD+KL +S AI +YIA ++ G + ++ + A++ I V Sbjct: 51 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 105 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL YL G+ T D Sbjct: 106 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDF 152 Query: 172 HHIPAIQYLL 181 A+ +L Sbjct: 153 MLYDALDVVL 162 >2IL3-A nrPDB Length = 221 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 50/221 (22%), Positives = 92/221 (41%), Gaps = 34/221 (15%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M+ + ++ S R V + L+ E + L G+H K F+ NP +P +D Sbjct: 1 MSNLVLYTLHLSPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVLDD 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 + ES AI Y+ +Y + +L D ++ V S L F Sbjct: 61 NGTIITESHAIMIYLVTKY-GKDDSLYPKDPVKQAR-----------------VNSALHF 102 Query: 121 EQ---------IFKSIYGLTTDEAVVAEEEAK-LAKVLDVYEARLKEFKYLAGETFTLTD 170 E IF+ I L ++ + E+ + + K ++ E L + ++AG T T+ D Sbjct: 103 ESGVLFARMRFIFERI--LFFGKSDIPEDRVEYVQKSYELLEDTLVD-DFVAGPTMTIAD 159 Query: 171 LHHIPAIQYLLG-TPTKKLFTERPRVNEWVAEITKRPASEK 210 I I ++G P ++ ++ PR+ W+ + + P E+ Sbjct: 160 FSCISTISSIMGVVPLEQ--SKHPRIYAWIDRLKQLPYYEE 198 >2GDR-A nrPDB Length = 202 Score = 40.4 bits (93), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 25/59 (42%), Positives = 32/59 (54%), Gaps = 2/59 (3%) Query: 20 IALHEKNLDFELVHVELKDGE-HKKEPFLSRNPFGQVPAFE-DGDLKLFESRAITQYIA 76 IAL E L+FELV V+L + + +L NP G VP + D L E AI QY+A Sbjct: 16 IALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDDGRTLTEGPAIVQYVA 74 >1DUG-A nrPDB Length = 234 Score = 40.4 bits (93), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 18/130 (13%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P + DGD+KL +S AI +YIA ++ G + ++ + A++ I V Sbjct: 51 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 105 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL YL G+ T D Sbjct: 106 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDF 152 Query: 172 HHIPAIQYLL 181 A+ +L Sbjct: 153 MLYDALDVVL 162 >3BBY-A nrPDB Length = 215 Score = 40.4 bits (93), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 32/60 (53%) Query: 20 IALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRY 79 +AL EK L F + ++L GEH + + +VP + D +L ES AI +Y+ R+ Sbjct: 25 VALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRF 84 >1BG5-A nrPDB Length = 254 Score = 40.0 bits (92), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 18/130 (13%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P + DGD+KL +S AI +YIA ++ G + ++ + A++ I V Sbjct: 52 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 106 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL YL G+ T D Sbjct: 107 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDF 153 Query: 172 HHIPAIQYLL 181 A+ +L Sbjct: 154 MLYDALDVVL 163 >4MDC-A nrPDB Length = 252 Score = 39.7 bits (91), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 50/221 (22%), Positives = 99/221 (44%), Gaps = 36/221 (16%) Query: 6 VFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLK- 64 ++ HP S A+R V + L E EL E + E++++ FL+ NP G +P + D ++ Sbjct: 26 LYHHPMSPASRFVRLILSEYGYQTELS--EEQPWENRRD-FLTLNPAGTLPVYVDDSMRA 82 Query: 65 LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF-----DPVASKLA 119 L + I++Y+ ++ + +++ D + +++ ++ F V L Sbjct: 83 LCGATIISEYL-----DETSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPLV 137 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF-----------KYLAGETFTL 168 E+IFK +T D+ A + +K+L + +++ +LAG+ + Sbjct: 138 RERIFK--LQMTPDQGGGAPD----SKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISY 191 Query: 169 TDLHHIPAIQYL--LGTPTKKLFTERPRVNEWVAEITKRPA 207 DL AI L LG + +++ P EW + RP+ Sbjct: 192 GDLAAAAAISVLDYLG---EIDWSDAPTAKEWYQRLKSRPS 229 >1N2A-A nrPDB Length = 201 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 49/180 (27%), Positives = 80/180 (44%), Gaps = 20/180 (11%) Query: 4 IKVFGHP--ASIATRRVLIALHEKNLDFELVHVEL-KDGEHKKEPFLSRNPFGQVPAFED 60 +K+F P S+A+ I L E DF LV V+L K + + + NP GQVPA Sbjct: 1 MKLFYKPGACSLASH---ITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLL 57 Query: 61 GDLKLF-ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 D L E AI QY+A ++ L +IS+Y + + +A++L Sbjct: 58 DDGTLLTEGVAIMQYLADSVPDRQ---LLAPVNSISRYKTI--------EWLNYIATEL- 105 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 + F ++ T E A+L K L LK+ ++ G+ FT+ D + +++ Sbjct: 106 -HKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVLRW 164 >4MK3-A nrPDB Length = 226 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 6/73 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAF--EDG 61 +K++ S R+V + L EK +D+E++ + + F NP G+VP EDG Sbjct: 23 MKLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRF---NPLGKVPCLVMEDG 79 Query: 62 DLKLFESRAITQY 74 +F+SR I +Y Sbjct: 80 G-AVFDSRVIAEY 91 >5F0G-A nrPDB Length = 215 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/172 (20%), Positives = 68/172 (39%), Gaps = 17/172 (9%) Query: 10 PASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESR 69 P R V++ L+ + +GE K F+ NP +P D ++ESR Sbjct: 7 PGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGFSIWESR 66 Query: 70 AITQYIAHRYENQGTNLLQTDSKN---ISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKS 126 AI Y+ +Y + LL D K I+Q +G E +F + + Sbjct: 67 AIAVYLVEKY-GKDDYLLPNDPKKRAVINQRLYFDMGTLYE-----------SFAKYYYP 114 Query: 127 IYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ 178 ++ T + E+ ++ + L+ +Y+AG+ T+ D+ + + Sbjct: 115 LF--RTGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVS 164 >1FW1-A nrPDB Length = 216 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%) Query: 12 SIATRRVLIALHEKNLDFELVHVEL-KDGEHK-KEPFLSRNPFGQVPAFEDGDLKLFESR 69 S + RV IAL K +D++ V + L KDG + + F + NP QVP + + + +S Sbjct: 14 SSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQSL 73 Query: 70 AITQYI 75 AI +Y+ Sbjct: 74 AIIEYL 79 >1TU7-A nrPDB Length = 208 Score = 37.7 bits (86), Expect = 0.004, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 27/42 (64%) Query: 48 SRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQT 89 S+ FGQ+P DGD ++ +S AI +++A +Y G N ++T Sbjct: 43 SQFQFGQLPCLYDGDQQIVQSGAILRHLARKYNLNGENEMET 84 >1VF1-A nrPDB Length = 229 Score = 37.4 bits (85), Expect = 0.005, Method: Compositional matrix adjust. Identities = 47/173 (27%), Positives = 76/173 (43%), Gaps = 30/173 (17%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F QVP E +KL ++RAI YIA +Y G K++ + A++ + + D Sbjct: 52 FQQVPMVEIDGMKLVQTRAILNYIAGKYNLYG--------KDLKERALIDMYVGGTD--- 100 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLT 169 D + L+F F S A V E+ ++ YE LK+ +L G + Sbjct: 101 DLMGFLLSFP--FLSAEDKVKQCAFVVEKAT--SRYFPAYEKVLKDHGQDFLVGNRLSWA 156 Query: 170 DLHHIPAI--------QYLLGTPTKKLFTER----PRVNEWVAEITKR-PASE 209 D+H + AI L G P + F +R P + +++A +KR P S+ Sbjct: 157 DIHLLEAILMVEEKKSDALSGFPLLQAFKKRISSIPTIKKFLAPGSKRKPISD 209 >2GLR-A nrPDB Length = 209 Score = 37.0 bits (84), Expect = 0.006, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 22/34 (64%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTN 85 +GQ+P FEDGDL L++S AI +++ G N Sbjct: 49 YGQLPKFEDGDLTLYQSNAILRHLGRSLGLYGKN 82 >1GWC-A nrPDB Length = 230 Score = 36.6 bits (83), Expect = 0.009, Method: Compositional matrix adjust. Identities = 31/94 (32%), Positives = 42/94 (44%), Gaps = 7/94 (7%) Query: 1 MAG---IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPF-GQVP 56 MAG +K+ G S RV +AL K L +E V +L K E L NP ++P Sbjct: 1 MAGGDDLKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLY---KKSELLLKSNPVHKKIP 57 Query: 57 AFEDGDLKLFESRAITQYIAHRYENQGTNLLQTD 90 + ES I QYI + + G +LL D Sbjct: 58 VLIHNGAPVCESMIILQYIDEVFASTGPSLLPAD 91 >18GS-A nrPDB Length = 210 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 6/66 (9%) Query: 13 IATRRVLIALHEKNLDFELVHVE-LKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 A R+L+A ++ E+V VE ++G K +GQ+P F+DGDL L++S I Sbjct: 15 CAALRMLLADQGQSWKEEVVTVETWQEGSLKASCL-----YGQLPKFQDGDLTLYQSNTI 69 Query: 72 TQYIAH 77 +++ Sbjct: 70 LRHLGR 75 >3LG6-A nrPDB Length = 235 Score = 36.2 bits (82), Expect = 0.010, Method: Compositional matrix adjust. Identities = 40/189 (21%), Positives = 74/189 (39%), Gaps = 26/189 (13%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAF------ 58 +++G+ S + R+ IA H K++ + V L GE + + S NP VP Sbjct: 11 ELYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVSNIN 70 Query: 59 -----EDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDP 113 + +S A +Y+ LL S +++ + I + P Sbjct: 71 NTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTI-CNIIACDVQP 129 Query: 114 VASKLAFEQIFKSIYGLTTDEAVVAEEEAK-----LAKVLDVYEARLKEFKYLAGETFTL 168 V + +I K + L D V + + A + K+L++ R + G+ TL Sbjct: 130 VTNL----KIQKKVKALDGDPTVWSRDLATQGFGAVEKLLELSAGR-----FCVGDEITL 180 Query: 169 TDLHHIPAI 177 D+ +PA+ Sbjct: 181 ADVCLVPAV 189 >5D73-A nrPDB Length = 208 Score = 36.2 bits (82), Expect = 0.012, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 25/38 (65%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQT 89 FGQ+P DGD ++ +S AI +++A ++ G N L+T Sbjct: 47 FGQLPCLYDGDHQIVQSGAILRHLARKHNLNGGNELET 84 >4IGJ-A nrPDB Length = 242 Score = 34.7 bits (78), Expect = 0.027, Method: Compositional matrix adjust. Identities = 41/180 (22%), Positives = 79/180 (43%), Gaps = 16/180 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAF---ED 60 ++++ + S + RV + L K L +E V+L E + +RNP QVP ED Sbjct: 25 LRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEED 84 Query: 61 GDLKLF-ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 G L +S AI +++ R+ LL D ++ + A+ V + P+ + L Sbjct: 85 GRTHLLVQSMAILEWLEERHPEPA--LLPPDLWGRAR--VRALAEHV-NSGTQPMQNALV 139 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKE--FKYLAGETFTLTDLHHIPAI 177 + + + G + A +A+ L E +++ ++ G+ TL D + +P + Sbjct: 140 LRMLREKVPGWDREWARFF-----IARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQL 194 >2AAW-A nrPDB Length = 222 Score = 34.3 bits (77), Expect = 0.039, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 5/50 (10%) Query: 34 VELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQG 83 VE K+ + +K+ PF QVP + GDL L +S+AI +Y++ +Y G Sbjct: 54 VEFKNFKKEKDT-----PFEQVPILQIGDLILAQSQAIVRYLSKKYNICG 98 >2GSR-A nrPDB Length = 207 Score = 34.3 bits (77), Expect = 0.040, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 34/63 (53%), Gaps = 6/63 (9%) Query: 17 RVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIA 76 R+L+A +++ E+V +E P F Q+P F+DGDL L++S AI +++ Sbjct: 18 RMLLADQDQSWKEEVVTME------TWPPLKPSCLFRQLPKFQDGDLTLYQSNAILRHLG 71 Query: 77 HRY 79 + Sbjct: 72 RSF 74 >1GSU-A nrPDB Length = 219 Score = 33.9 bits (76), Expect = 0.049, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 33/67 (49%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P DGD+KL +S AI +YIA ++ G ++ ++ + +M + M + Sbjct: 56 FPNLPYLIDGDVKLTQSNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCY 115 Query: 112 DPVASKL 118 P KL Sbjct: 116 SPDFEKL 122 >1F3B-A nrPDB Length = 222 Score = 33.9 bits (76), Expect = 0.052, Method: Compositional matrix adjust. Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 17/131 (12%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F QVP E +KL ++RAI YIA +Y+ G ++ + ++ I+ + + Sbjct: 51 FDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDMKERALIDMYSEGILDLTEMIGQLVL 110 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLT 169 P + A + +A++ K + L +E LK YL G T Sbjct: 111 CPPDQREA--------------KTALAKDRTK-NRYLPAFEKVLKSHGQDYLVGNRLTRV 155 Query: 170 DLHHIPAIQYL 180 D+H + + Y+ Sbjct: 156 DIHLLEVLLYV 166 >3I6A-A nrPDB Length = 222 Score = 33.5 bits (75), Expect = 0.068, Method: Compositional matrix adjust. Identities = 31/131 (23%), Positives = 51/131 (38%), Gaps = 17/131 (12%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F QVP E +KL ++RAI YIA +Y G ++ + ++ I +G + F Sbjct: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMIIMLPF 111 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLT 169 P K D + +E + +E LK YL G + Sbjct: 112 CPPEEK---------------DAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRA 156 Query: 170 DLHHIPAIQYL 180 D+H + + Y+ Sbjct: 157 DIHLVELLYYV 167 >4Q5Q-A nrPDB Length = 219 Score = 33.5 bits (75), Expect = 0.069, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 23/34 (67%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTN 85 F +P + DGD+K+ ++ AI +Y+ +Y+ G+N Sbjct: 58 FPNLPYYIDGDMKMTQTFAILRYLGRKYKLNGSN 91 >1EV4-A nrPDB Length = 221 Score = 33.5 bits (75), Expect = 0.072, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 22/35 (62%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 F QVP E +KL ++RAI YIA +Y+ G ++ Sbjct: 51 FDQVPMVEIDGMKLAQTRAILNYIATKYDLYGKDM 85 >5LCZ-A nrPDB Length = 222 Score = 33.5 bits (75), Expect = 0.078, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 F QVP E +KL ++RAI YIA +Y G ++ Sbjct: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDM 86 >5AN1-A nrPDB Length = 219 Score = 33.1 bits (74), Expect = 0.078, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 28/42 (66%), Gaps = 3/42 (7%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTN---LLQTD 90 F +P + DGD+K+ +S+AI +Y+A ++ GT L++TD Sbjct: 57 FPNLPYYIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTD 98 >2VCT-A nrPDB Length = 222 Score = 33.1 bits (74), Expect = 0.080, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 F QVP E +KL ++RAI YIA +Y G ++ Sbjct: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDI 86 >2VCV-A nrPDB Length = 222 Score = 33.1 bits (74), Expect = 0.087, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 F QVP E +KL ++RAI YIA +Y G ++ Sbjct: 52 FQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDI 86 >1B48-A nrPDB Length = 221 Score = 33.1 bits (74), Expect = 0.10, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 FGQVP E + L ++RAI Y+A +Y G +L Sbjct: 51 FGQVPLVEIDGMMLTQTRAILSYLAAKYNLYGKDL 85 >1GUL-A nrPDB Length = 222 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 8/52 (15%) Query: 35 ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 +L+DG H F QVP E +KL ++R+I YIA ++ G NL Sbjct: 43 KLQDGNHLL--------FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNL 86 >1PL2-A nrPDB Length = 222 Score = 32.7 bits (73), Expect = 0.12, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 20/35 (57%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNL 86 F QVP E +KL + RAI YIA +Y G ++ Sbjct: 52 FQQVPMVEIDGMKLVQERAILNYIASKYNLYGKDI 86 >3RBT-A nrPDB Length = 246 Score = 32.3 bits (72), Expect = 0.15, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 7/67 (10%) Query: 17 RVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE----DGDLKLFESRAIT 72 RVL+ L K + +E+ + D E F ++NP ++P E GD LFES I Sbjct: 40 RVLLVLEAKRIKYEVYRL---DPLRLPEWFRAKNPRLKIPVLEIPTDQGDRFLFESVVIC 96 Query: 73 QYIAHRY 79 Y+ +Y Sbjct: 97 DYLDEKY 103 >1HNA-A nrPDB Length = 217 Score = 31.2 bits (69), Expect = 0.36, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 33/67 (49%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P DG K+ +S AI +YIA ++ G + + ++I + M MQ+ + Sbjct: 56 FPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCY 115 Query: 112 DPVASKL 118 DP KL Sbjct: 116 DPDFEKL 122 >4Q5F-A nrPDB Length = 218 Score = 30.8 bits (68), Expect = 0.45, Method: Compositional matrix adjust. Identities = 51/205 (24%), Positives = 87/205 (42%), Gaps = 42/205 (20%) Query: 26 NLDFELVHVELKDGEHKKEPFLS---RNPFGQVPAFE-DGDLKLFESRAITQYIAHRYEN 81 L F V+ +D K+E + + + PFGQ+P E DG++ L +S AI +Y+ ++ Sbjct: 31 RLIFHQAGVKFEDNRLKREDWPALKPKTPFGQLPLLEVDGEV-LAQSAAIYRYLGRQFGL 89 Query: 82 QGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA-FEQIFKSIYGL-TTDEAVVAE 139 G ++ QV D FD +A F+ + G D+ V + Sbjct: 90 AGKTPMEE--------------AQV-DSIFDQFKDFMAELRPCFRVLAGFEEGDKEKVLK 134 Query: 140 EEAKLAKVLDVYEARLKEF------KYLAGETFTLTDLHHIPAI--------QYLLGTPT 185 E A A+ D + L++F +Y+ G++ T DL ++ +L G Sbjct: 135 EVAVPAR--DKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGHLQ 192 Query: 186 KKLFTER----PRVNEWVAEITKRP 206 K + E P + +W+AE K P Sbjct: 193 LKKYIEHVRELPNIKKWIAERPKTP 217 >1ZL9-A nrPDB Length = 207 Score = 30.4 bits (67), Expect = 0.56, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 14/67 (20%) Query: 51 PFGQVPAFEDGDLKLFESRAITQYIAHRYENQG--------TNLLQTDSKNISQ------ 96 PFGQ+P E KL +S AI +++A ++ G N L K+ S Sbjct: 49 PFGQLPFLEVDGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYF 108 Query: 97 YAIMAIG 103 YA+M G Sbjct: 109 YAVMGFG 115 >3NIV-A nrPDB Length = 222 Score = 29.6 bits (65), Expect = 1.0, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKD--GEHKKEPFLSRNPFGQVPAFEDGDLKLFESR 69 S A RV IAL+ K + +E + V L + GE + NP VP+ + L +S Sbjct: 11 STACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDINGQILSQSM 70 Query: 70 AITQYI 75 AI Y+ Sbjct: 71 AIIDYL 76 >1Y1X-A nrPDB Length = 191 Score = 28.5 bits (62), Expect = 2.1, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 10/73 (13%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEH----KKEPFLSRNPFGQVPA 57 A + G P S+AT L+ +++KN E+ E KD H +E F R+ G Sbjct: 51 AALSSAGVPFSLATTEKLLHMYDKNHSGEITFDEFKDLHHFILSMREGFRKRDSSG---- 106 Query: 58 FEDGDLKLFESRA 70 DG L E RA Sbjct: 107 --DGRLDSNEVRA 117 >3GTU-B nrPDB Length = 224 Score = 28.5 bits (62), Expect = 2.4, Method: Compositional matrix adjust. Identities = 30/120 (25%), Positives = 50/120 (41%), Gaps = 18/120 (15%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P DG K+ +S AI +YIA ++ G +T+ + I + I QV D + Sbjct: 60 FPNLPYLLDGKNKITQSNAILRYIARKHNMCG----ETEEEKIR---VDIIENQVMDFR- 111 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 Q+ + Y + E + + +L L + L +F + AGE T D Sbjct: 112 ---------TQLIRLCYS-SDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDF 161 >3H0K-A nrPDB Length = 178 Score = 28.1 bits (61), Expect = 2.7, Method: Compositional matrix adjust. Identities = 26/100 (26%), Positives = 46/100 (46%), Gaps = 22/100 (22%) Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 D V ++L E++ G + + VV + LA+V +EFK L G++ + + Sbjct: 61 DGVVARLCVEEL-----GTSNHDLVVFDGVRSLAEV--------EEFKRLLGDSVYIVAV 107 Query: 172 HHIPAIQYLLGTPTKKLFTERPRVNEW--VAEITKRPASE 209 H P I+Y K ER R ++ ++E+ +R E Sbjct: 108 HSPPKIRY-------KRMIERLRSDDSKEISELIRRDREE 140 >5E5B-A nrPDB Length = 431 Score = 28.1 bits (61), Expect = 3.0, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 31/57 (54%) Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ 178 ++F + E V A+E+ + +K+ + E ++E KYLAG + ++ + P IQ Sbjct: 191 EVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQ 247 >3VZI-A nrPDB Length = 226 Score = 28.1 bits (61), Expect = 3.2, Method: Compositional matrix adjust. Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 4/57 (7%) Query: 114 VASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTD 170 V SKL+ I K+I TDE V EE + + V L+E Y+ F +TD Sbjct: 74 VGSKLSAASISKAIKAGRTDELVKYVEEDRQQRAATV----LREVGYIIAAHFEMTD 126 >1T1U-A nrPDB Length = 639 Score = 28.1 bits (61), Expect = 3.2, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 18/73 (24%) Query: 55 VPAFEDGDLKLFES-----------------RAITQYIAHRYENQGTNLLQTDSKNISQY 97 VP +E ++ F+ +A+T + A ++ LLQT + ++Y Sbjct: 442 VPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQAQTEY 501 Query: 98 AIMAI-GMQVEDH 109 +MAI GM +++H Sbjct: 502 TVMAITGMAIDNH 514 >3KXO-A nrPDB Length = 202 Score = 27.3 bits (59), Expect = 4.7, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 18/34 (52%) Query: 51 PFGQVPAFEDGDLKLFESRAITQYIAHRYENQGT 84 PFG++P E L L +S AI +Y+ + G Sbjct: 50 PFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGN 83 >2ENX-A nrPDB Length = 310 Score = 27.3 bits (59), Expect = 4.8, Method: Compositional matrix adjust. Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 6/76 (7%) Query: 99 IMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLD---VYEARL 155 I+ G Q D D + S +AF + K +GL T+ + + A VLD V R+ Sbjct: 3 ILVFGHQNPDS--DAIGSSVAFAYLAKEAWGLDTEAVALGTPNEETAYVLDYFGVQAPRV 60 Query: 156 KEFKYLAG-ETFTLTD 170 E G ET LTD Sbjct: 61 VESAKAEGVETVILTD 76 >5Y9Z-A nrPDB Length = 199 Score = 27.3 bits (59), Expect = 4.9, Method: Compositional matrix adjust. Identities = 12/33 (36%), Positives = 18/33 (54%) Query: 51 PFGQVPAFEDGDLKLFESRAITQYIAHRYENQG 83 PFG++P E L L +S AI +Y+ + G Sbjct: 47 PFGKIPVLEVEGLTLHQSLAIARYLTKNTDLAG 79 >1K20-A nrPDB Length = 310 Score = 27.3 bits (59), Expect = 5.0, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 99 IMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVY 151 I+ G Q D D + S AF + + YGL T+ + E + A VLD + Sbjct: 3 ILVFGHQNPDS--DAIGSSYAFAYLAREAYGLDTEAVALGEPNEETAFVLDYF 53 >5UJY-A nrPDB Length = 706 Score = 26.9 bits (58), Expect = 6.1, Method: Compositional matrix adjust. Identities = 41/147 (27%), Positives = 57/147 (38%), Gaps = 34/147 (23%) Query: 31 LVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI------TQYIAHR-YENQG 83 L +L +++P+ +R P+ P F L+ SR + T IA R YEN Sbjct: 286 LDGTQLTVASAEEKPY-ARRPY---PPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGY 341 Query: 84 TNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAK 143 ++TDS +S+ AI A Q + +YG DE V Sbjct: 342 ITYMRTDSTTLSESAINAARTQA------------------RQLYG---DEYVAPAPRQY 380 Query: 144 LAKVLDVYEARLKEFKYLAGETFTLTD 170 KV + EA E AGETF D Sbjct: 381 TRKVKNAQEA--HEAIRPAGETFATPD 405 >4BSZ-B nrPDB Length = 202 Score = 26.9 bits (58), Expect = 6.9, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%) Query: 21 ALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE 59 ALH +L+ +L V+L E++ +PF+ RN FG FE Sbjct: 98 ALHWASLNGKLDVVKLLCDEYEADPFI-RNKFGHDAIFE 135 >1G0A-B nrPDB Length = 145 Score = 26.6 bits (57), Expect = 8.5, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 121 EQIFKSIYGLTTDEAVVAEEEAKL--AKVLDVYEARLKEFKYLAGETFTLTDLH 172 ++ F+S L+T +AV+ + K KVLD + +K L G L++LH Sbjct: 38 QRFFESFGDLSTADAVMNNPKVKAHGKKVLDSFSNGMKHLDDLKGTFAALSELH 91 >1FHJ-B nrPDB Length = 146 Score = 26.6 bits (57), Expect = 9.0, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 121 EQIFKSIYGLTTDEAVVAEEEAKL--AKVLDVYEARLKEFKYLAGETFTLTDLH 172 ++ F S L+T +AV++ + K KVL+ + LK L G L++LH Sbjct: 39 QRFFDSFGDLSTPDAVMSNAKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELH 92 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5A5K-A nrPDB 268 1e-72 5F06-A nrPDB 243 5e-65 5F05-A nrPDB 235 9e-63 1AW9-A nrPDB 232 1e-61 5EY6-A nrPDB 226 4e-60 5F07-A nrPDB 222 1e-58 1AXD-A nrPDB 215 1e-56 6F05-A nrPDB 214 2e-56 4RI7-A nrPDB 211 2e-55 4PNG-A nrPDB 181 3e-46 4YH2-A nrPDB 171 2e-43 3VWX-A nrPDB 171 3e-43 2IL3-A nrPDB 164 2e-41 4MPF-A nrPDB 163 5e-41 5ZWP-A nrPDB 162 7e-41 1JLV-A nrPDB 162 1e-40 1PN9-A nrPDB 155 1e-38 3M3M-A nrPDB 155 1e-38 3M8N-A nrPDB 153 6e-38 2C3Q-A nrPDB 152 1e-37 3MAK-A nrPDB 151 2e-37 3IBH-A nrPDB 150 5e-37 3TOT-A nrPDB 147 2e-36 1E6B-A nrPDB 145 2e-35 3GX0-A nrPDB 144 2e-35 1G6W-A nrPDB 142 1e-34 2JL4-A nrPDB 139 8e-34 3LSZ-A nrPDB 139 1e-33 2PMT-A nrPDB 136 7e-33 3C8E-A nrPDB 136 8e-33 3LFL-A nrPDB 135 2e-32 4IKH-A nrPDB 130 4e-31 4MDC-A nrPDB 129 7e-31 1F2E-A nrPDB 128 1e-30 4MK3-A nrPDB 127 4e-30 4PXO-A nrPDB 126 6e-30 4QQ7-A nrPDB 126 8e-30 3UBL-A nrPDB 123 6e-29 2CZ2-A nrPDB 121 2e-28 1N2A-A nrPDB 121 3e-28 2GDR-A nrPDB 116 7e-27 5D9W-A nrPDB 104 4e-23 5IQY-A nrPDB 100 7e-22 6JWK-A nrPDB 96 1e-20 1B8X-A nrPDB 94 4e-20 1BG5-A nrPDB 94 4e-20 1DUG-A nrPDB 94 5e-20 3BBY-A nrPDB 86 1e-17 Sequences not found previously or not previously below threshold: 5F0G-A nrPDB 142 9e-35 3GH6-A nrPDB 141 3e-34 1FW1-A nrPDB 121 3e-28 3UAR-A nrPDB 119 9e-28 1V2A-A nrPDB 110 5e-25 5NR1-A nrPDB 109 1e-24 3QAG-A nrPDB 108 2e-24 4IGJ-A nrPDB 104 3e-23 3NIV-A nrPDB 104 4e-23 4J2F-A nrPDB 102 1e-22 4CHS-A nrPDB 100 3e-22 2VO4-A nrPDB 98 3e-21 3LG6-A nrPDB 97 6e-21 5ELG-A nrPDB 96 1e-20 5J5N-A nrPDB 94 6e-20 6EP7-A nrPDB 93 9e-20 3PR8-A nrPDB 93 1e-19 5ECL-B nrPDB 91 2e-19 5G5A-A nrPDB 90 7e-19 5LOL-A nrPDB 89 1e-18 3RBT-A nrPDB 89 1e-18 5F8B-A nrPDB 87 4e-18 4WR5-A nrPDB 87 6e-18 5D73-A nrPDB 87 6e-18 3R2Q-A nrPDB 86 8e-18 5N9U-A nrPDB 86 1e-17 2PVQ-A nrPDB 85 2e-17 3WD6-A nrPDB 84 3e-17 2FHE-A nrPDB 80 8e-16 1GWC-A nrPDB 79 1e-15 2WRT-A nrPDB 78 3e-15 4AGS-A nrPDB 77 4e-15 1OYJ-A nrPDB 77 7e-15 5AN1-A nrPDB 76 8e-15 2VCT-A nrPDB 76 8e-15 1VF1-A nrPDB 76 1e-14 3I6A-A nrPDB 76 1e-14 1PL2-A nrPDB 76 1e-14 2GLR-A nrPDB 76 1e-14 1HNA-A nrPDB 75 2e-14 1FHE-A nrPDB 75 3e-14 2DC5-A nrPDB 74 3e-14 1XWK-A nrPDB 74 4e-14 1F3B-A nrPDB 73 8e-14 18GS-A nrPDB 73 9e-14 2VCV-A nrPDB 73 9e-14 1B4P-A nrPDB 72 1e-13 5FWG-A nrPDB 72 1e-13 4GTU-A nrPDB 72 2e-13 1TU7-A nrPDB 71 3e-13 4Q5F-A nrPDB 71 3e-13 1B48-A nrPDB 71 3e-13 5LCZ-A nrPDB 71 4e-13 2GSR-A nrPDB 70 8e-13 4PQI-A nrPDB 69 1e-12 3KXO-A nrPDB 68 2e-12 1GSQ-A nrPDB 67 4e-12 1EV4-A nrPDB 67 5e-12 1ZL9-A nrPDB 67 7e-12 4Q5Q-A nrPDB 66 1e-11 1GSU-A nrPDB 66 2e-11 4Q5R-A nrPDB 65 2e-11 3GTU-B nrPDB 65 3e-11 2AAW-A nrPDB 65 3e-11 1YQ1-A nrPDB 65 3e-11 1GUL-A nrPDB 64 6e-11 6GC9-A nrPDB 62 2e-10 5Y9Z-A nrPDB 62 2e-10 2WDU-A nrPDB 61 3e-10 1U3I-A nrPDB 61 3e-10 3FY7-A nrPDB 61 4e-10 2HNL-A nrPDB 61 5e-10 3PPU-A nrPDB 60 8e-10 4FQU-A nrPDB 59 1e-09 4K0G-A nrPDB 58 3e-09 2CA8-A nrPDB 58 3e-09 3M1G-A nrPDB 57 5e-09 4LMW-A nrPDB 51 3e-07 4G0L-A nrPDB 50 6e-07 5Y7I-A nrPDB 49 1e-06 6GZF-A nrPDB 49 2e-06 4USS-A nrPDB 47 4e-06 6GCB-A nrPDB 47 5e-06 4PTS-A nrPDB 47 6e-06 4BVY-B nrPDB 47 6e-06 1M0U-A nrPDB 47 8e-06 2D2Z-A nrPDB 46 2e-05 1G7O-A nrPDB 42 2e-04 2PBJ-A nrPDB 41 4e-04 2R5G-A nrPDB 41 4e-04 3IC4-A nrPDB 41 5e-04 4LMV-A nrPDB 40 9e-04 5CAX-A nrPDB 39 0.001 3GRX-A nrPDB 35 0.021 2YV9-A nrPDB 33 0.075 2MZC-A nrPDB 33 0.077 2KLX-A nrPDB 31 0.34 1H75-A nrPDB 31 0.36 1S4D-A nrPDB 30 0.52 2X8H-A nrPDB 30 0.66 5L0V-A nrPDB 30 0.87 6HQD-A nrPDB 30 0.94 5LKB-A nrPDB 30 0.97 5MB9-A nrPDB 29 1.2 4HQS-A nrPDB 29 1.3 4FIW-A nrPDB 29 1.4 3IHQ-A nrPDB 29 1.5 4TR1-A nrPDB 29 1.5 4EVM-A nrPDB 29 2.4 1JOE-A nrPDB 28 2.4 3QMX-A nrPDB 28 2.5 4WZ9-A nrPDB 28 2.6 3W0K-A nrPDB 28 2.7 3NZN-A nrPDB 28 3.0 3ZIT-A nrPDB 28 3.3 1HH2-P nrPDB 27 4.2 6HIV-Cd nrPDB 27 7.2 >5A5K-A nrPDB Length = 212 Score = 268 bits (685), Expect = 1e-72, Method: Composition-based stats. Identities = 212/212 (100%), Positives = 212/212 (100%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED Sbjct: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF Sbjct: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL Sbjct: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ Sbjct: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 >5F06-A nrPDB Length = 216 Score = 243 bits (619), Expect = 5e-65, Method: Composition-based stats. Identities = 96/208 (46%), Positives = 141/208 (67%), Gaps = 2/208 (0%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +K++G P S T RVL LHEKNLDFELV V+L GEHK+ PFL++NPFGQ+PA E+ DL Sbjct: 2 LKLYGAPMSTCTSRVLTCLHEKNLDFELVPVDLFAGEHKQPPFLAKNPFGQIPALEEDDL 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 LFESRAIT YIA +++ G +L++ +N+ + A + + +VE H+++P + + F+ + Sbjct: 62 TLFESRAITSYIAEKFKGTGYDLIR--HENLKEAASVKVWTEVESHRYNPAIAPIVFQFM 119 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 + G + D+ ++ + KL KVLD+YEA+L KYLAG+ ++L DLHH+P YL+ T Sbjct: 120 VAPLRGNSPDQTIIDDNVEKLGKVLDIYEAKLSSTKYLAGDFYSLADLHHLPYTYYLMKT 179 Query: 184 PTKKLFTERPRVNEWVAEITKRPASEKV 211 P + ERP V W +I+ RPA +KV Sbjct: 180 PAASVVNERPHVKAWWEDISSRPAFKKV 207 >5F05-A nrPDB Length = 212 Score = 235 bits (600), Expect = 9e-63, Method: Composition-based stats. Identities = 125/210 (59%), Positives = 154/210 (73%), Gaps = 4/210 (1%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A +K+ G S T+RVL L+EK ++FELV+V L GEHK+EP +S NPFGQVPA DG Sbjct: 1 APLKLHGSVLSTNTQRVLATLYEKEVEFELVNVNLGAGEHKQEPHISLNPFGQVPAAVDG 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 DLKLFESRAI+QY+AH+Y ++GT L + YA + + +VE HQFDP ASKL +E Sbjct: 61 DLKLFESRAISQYVAHQYASKGTQLGAAG----NGYATILVWQEVESHQFDPSASKLVWE 116 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 Q+FK ++GL TD A+VAE E L KVLDVYEARL + KYLA ++FTL DLHH+P IQ LL Sbjct: 117 QVFKPVFGLPTDAALVAETEVTLGKVLDVYEARLSQSKYLASDSFTLADLHHLPNIQALL 176 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKV 211 GTP+KKLF RP V+ WVA IT RPA KV Sbjct: 177 GTPSKKLFDSRPHVSAWVASITGRPAWGKV 206 >1AW9-A nrPDB Length = 216 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 97/209 (46%), Positives = 126/209 (60%), Gaps = 4/209 (1%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A +K++G P S RV L+EK LDFE+V V+L G HK+ FL+ NPFGQ+PA DG Sbjct: 1 APLKLYGMPLSPNVVRVATVLNEKGLDFEIVPVDLTTGAHKQPDFLALNPFGQIPALVDG 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 D LFESRAI +YIA +Y ++GT+LL + A + + ++VE H F P AS L F+ Sbjct: 61 DEVLFESRAINRYIASKYASEGTDLLPAT----ASAAKLEVWLEVESHHFYPNASPLVFQ 116 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + + + G D AVV + +LAKVLDVYEA L KYLAG+ FTL D +H + YL Sbjct: 117 LLVRPLLGGAPDAAVVDKHAEQLAKVLDVYEAHLARNKYLAGDEFTLADANHASYLLYLS 176 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEK 210 TP L RP V W I RPA +K Sbjct: 177 KTPKAGLVAARPHVKAWWEAIVARPAFQK 205 >5EY6-A nrPDB Length = 217 Score = 226 bits (577), Expect = 4e-60, Method: Composition-based stats. Identities = 84/210 (40%), Positives = 122/210 (58%), Gaps = 3/210 (1%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 +KV+G P S A RVL+ L EK++ F+++ V++ GEHKK +L PFGQVPAF+D Sbjct: 3 PVKVYGPPLSTAVSRVLVTLLEKDVPFQIIPVDMSKGEHKKPDYLKIQPFGQVPAFQDES 62 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + LFESR+I +Y+ +Y ++G L N + A + ++ E F P + L F+ Sbjct: 63 ISLFESRSICRYVCEKYADRGDKGLY--GTNPLERASIDQWVEAEGQSFGPSSGALVFQL 120 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 F + D+ V+ + E KL KVLD+YE RL E ++LAG+ FT DL H+P YL+ Sbjct: 121 AFAPRMNIPQDQGVIKQNEEKLGKVLDIYEQRLGESRFLAGDEFTFADLSHLPNGDYLVN 180 Query: 183 TPTKK-LFTERPRVNEWVAEITKRPASEKV 211 K LFT R V W EI+ R + +KV Sbjct: 181 ATDKGHLFTSRENVGRWWNEISDRESWKKV 210 >5F07-A nrPDB Length = 213 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 89/209 (42%), Positives = 130/209 (62%), Gaps = 4/209 (1%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +KV+G ++ +RV+ L EK ++F+LVHV+L GE K FL + PFGQVP EDGD Sbjct: 2 VKVYGPAVAVCPQRVMACLLEKGVEFDLVHVDLDSGEQKLPEFLLKQPFGQVPVVEDGDF 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 KLFESRAI +Y A +YE++G NLL + + A++ +++E H F+ + + F+ + Sbjct: 62 KLFESRAIIRYYAAKYEDRGPNLL---GNTLEEKALVDQWLEIEAHNFNDLVFNIVFQVV 118 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG- 182 G D +V E KL KVLDVYE RL + KYLAG++FTL DL H+PA +YL+ Sbjct: 119 ILPRIGQQGDSELVRTYEEKLEKVLDVYEKRLSKSKYLAGDSFTLADLSHLPATRYLVNE 178 Query: 183 TPTKKLFTERPRVNEWVAEITKRPASEKV 211 L +R ++N W +I+ RPA +K+ Sbjct: 179 AGLGHLVKDRKKLNAWWEDISSRPAWKKL 207 >1AXD-A nrPDB Length = 209 Score = 215 bits (547), Expect = 1e-56, Method: Composition-based stats. Identities = 82/210 (39%), Positives = 120/210 (57%), Gaps = 5/210 (2%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A +K++G S R AL E D+E+V + EHK L RNPFGQVPA +DG Sbjct: 1 APMKLYGAVMSWNLTRCATALEEAGSDYEIVPINFATAEHKSPEHLVRNPFGQVPALQDG 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 DL LFESRAI +Y A + + LL+ N+ + A++ + ++VE +Q+ + + F+ Sbjct: 61 DLYLFESRAICKYAARKNK---PELLREG--NLEEAAMVDVWIEVEANQYTAALNPILFQ 115 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + + G TTD+ VV E KL KVL+VYEARL + KYLAG+ +L DL+H+ L Sbjct: 116 VLISPMLGGTTDQKVVDENLEKLKKVLEVYEARLTKCKYLAGDFLSLADLNHVSVTLCLF 175 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKV 211 TP + P V W + + +RP+ +KV Sbjct: 176 ATPYASVLDAYPHVKAWWSGLMERPSVQKV 205 >6F05-A nrPDB Length = 215 Score = 214 bits (544), Expect = 2e-56, Method: Composition-based stats. Identities = 83/208 (39%), Positives = 122/208 (58%), Gaps = 5/208 (2%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +KV+G + +R L+ L EK + FE + V+L GEHK+ +L+ PFG VPA DGD Sbjct: 3 LKVYGPHFASP-KRALVTLIEKGVAFETIPVDLMKGEHKQPAYLALQPFGTVPAVVDGDY 61 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 K+FESRA+ +Y+A +Y +QG +LL K + + + VE + P L + Sbjct: 62 KIFESRAVMRYVAEKYRSQGPDLL---GKTVEDRGQVEQWLDVEATTYHPPLLNLTLHIM 118 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 F S+ G +DE ++ E E KLA VLDVYEA L + KYLAG+ +L DL H+P YL+G Sbjct: 119 FASVMGFPSDEKLIKESEEKLAGVLDVYEAHLSKSKYLAGDFVSLADLAHLPFTDYLVGP 178 Query: 184 PTKK-LFTERPRVNEWVAEITKRPASEK 210 K + +R V+ W +I+ RPA ++ Sbjct: 179 IGKAYMIKDRKHVSAWWDDISSRPAWKE 206 >4RI7-A nrPDB Length = 215 Score = 211 bits (537), Expect = 2e-55, Method: Composition-based stats. Identities = 81/210 (38%), Positives = 121/210 (57%), Gaps = 6/210 (2%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 + ++G P A RVL L EK++ F L+ ++L GE KK +L PFGQVPAF+D Sbjct: 4 PVTIYGPPLCTAVSRVLATLIEKDVPFHLIPIDLSKGEQKKPEYLKIQPFGQVPAFKDES 63 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + LFESRAI +YI +Y ++G L +I A + ++ + F P + L + Sbjct: 64 ITLFESRAICRYICDKYADKGNKSLY--GTDILSKANIDQWVETDGQTFGPPSGDLVHDL 121 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 +F S+ DEA++ + KLAKVLD+YE +L + ++LAG+ F+ DL H+P YL+ Sbjct: 122 LFSSV---PVDEALIKKNVDKLAKVLDIYEQKLGQTRFLAGDEFSFADLSHLPNGDYLVN 178 Query: 183 TPTKK-LFTERPRVNEWVAEITKRPASEKV 211 + K LFT R VN W EI+ R + +KV Sbjct: 179 STDKGYLFTSRKNVNRWWTEISNRESWKKV 208 >4PNG-A nrPDB Length = 229 Score = 181 bits (458), Expect = 3e-46, Method: Composition-based stats. Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 10/212 (4%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++G AS R V + L + +E V V + E+ E FL +NP VP ED Sbjct: 7 MPKLILYGLEASPPVRAVKLTLAALEVPYEFVEVNTRAKENFSEEFLKKNPQHTVPTLED 66 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +++S AI Y+ +Y + L D + Q A++ + E V A Sbjct: 67 DGHYIWDSHAIIAYLVSKYGKTDS-LYPKD---LLQRAVVDQRLHFESG----VIFANAL 118 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 I K ++ + E + +V D E L Y+AG T+ D I + L Sbjct: 119 RSITKPLFAGK-QTMIPKERYDAIIEVYDFLEKFLAGNDYVAGNQLTIADFSIISTVSSL 177 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 K T+ PR+ W + K P E+ Sbjct: 178 E-VFVKVDTTKYPRIAAWFKRLQKLPYYEEAN 208 >4YH2-A nrPDB Length = 222 Score = 171 bits (432), Expect = 2e-43, Method: Composition-based stats. Identities = 49/215 (22%), Positives = 86/215 (40%), Gaps = 16/215 (7%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++G S R V + L NL +E V+V++ +L +NP VP ED Sbjct: 1 MVKLTLYGLDPSPPVRAVKLTLAALNLTYEYVNVDIVARAQLSPEYLEKNPQHTVPTLED 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +++S AI Y+ +Y + L D + A++ + E S + F Sbjct: 61 DGHYIWDSHAIIAYLVSKYADSDA-LYPKDP---LKRAVVDQRLHFE--------SGVVF 108 Query: 121 EQIFKSIYG---LTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAI 177 +SI V E + ++ D E LK Y+AG T+ D + ++ Sbjct: 109 ANGIRSISKSVLFQGQTKVPKERYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSV 168 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 L T+ PR+ W+ ++ + P E+ Sbjct: 169 ASLE-AFVALDTTKYPRIGAWIKKLEQLPYYEEAN 202 >3VWX-A nrPDB Length = 222 Score = 171 bits (432), Expect = 3e-43, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 88/212 (41%), Gaps = 10/212 (4%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++G S R L+ L NL FE V L EH E +L +NP VP E+ Sbjct: 1 MGKLVLYGIDPSPPVRACLLTLKALNLPFEYKVVNLFAKEHLSEEYLKKNPQHTVPTLEE 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +++S AI Y+ +Y + L D + + A++ M E V + Sbjct: 61 DGHLIWDSHAIMAYLVSKYGKDDS-LYPKD---LLKRAVVDQRMYFEAG----VLFQGGL 112 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 I ++ + + + + E+ LK KY+AG+ T+ D + ++ L Sbjct: 113 RNITAPLF-FRNQTQIPQHQIDSIVESYGFLESFLKNNKYMAGDHLTIADFSIVTSVTSL 171 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 + + ++ P+++ W+ + P E+ Sbjct: 172 VAFA-EIDQSKFPKLSAWLKSLQSLPFYEEAN 202 >2IL3-A nrPDB Length = 221 Score = 164 bits (416), Expect = 2e-41, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 81/212 (38%), Gaps = 12/212 (5%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M+ + ++ S R V + L+ E + L G+H K F+ NP +P +D Sbjct: 1 MSNLVLYTLHLSPPCRAVELTAKALGLELEQKTINLLTGDHLKPEFVKLNPQHTIPVLDD 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 + ES AI Y+ +Y + L D ++ F+ Sbjct: 61 NGTIITESHAIMIYLVTKYGKDDS-LYPKDPVKQARVN--------SALHFESGVLFARM 111 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 IF+ I + + + + K ++ E L + ++AG T T+ D I I + Sbjct: 112 RFIFERILFFGKSD-IPEDRVEYVQKSYELLEDTLVD-DFVAGPTMTIADFSCISTISSI 169 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 +G ++ PR+ W+ + + P E+ Sbjct: 170 MGV-VPLEQSKHPRIYAWIDRLKQLPYYEEAN 200 >4MPF-A nrPDB Length = 266 Score = 163 bits (412), Expect = 5e-41, Method: Composition-based stats. Identities = 53/214 (24%), Positives = 88/214 (41%), Gaps = 12/214 (5%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 G+++F S +R V I + + EL V+L G+HK + FL N G++P +DGD Sbjct: 24 GLELFLDLVSQPSRAVYIFAKKNGIPLELRTVDLVKGQHKSKEFLQINSLGKLPTLKDGD 83 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA--- 119 L ES AI Y++ +Y+ D S A + D + Sbjct: 84 FILTESSAILIYLSCKYQTP-------DHWYPSDLQARARVHEYLGWHADCIRGTFGIPL 136 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEA-RLKEFKYLAGETFTLTDLHHIPAIQ 178 + Q+ + G+ + V + + L E L + +LAG+ TL DL + + Sbjct: 137 WVQVLGPLIGVQVPKEKVERNRTAMDQALQWLEDKFLGDRPFLAGQQVTLADLMALEELM 196 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 + +LF RPR+ W + +E Q Sbjct: 197 QPVALGY-ELFEGRPRLAAWRGRVEAFLGAELCQ 229 >5ZWP-A nrPDB Length = 208 Score = 162 bits (411), Expect = 7e-41, Method: Composition-based stats. Identities = 50/210 (23%), Positives = 81/210 (38%), Gaps = 18/210 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 + + P S R VL+ ++ + L+ GEH K FL NP +P DGD Sbjct: 1 MDFYYLPGSAPCRSVLMTAKALGIELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDGDF 60 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKN--ISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L+ESRAI Y+ +Y + + K I+Q +G + + + Sbjct: 61 ALWESRAIMVYLVEKYGKTDSLFPKCPKKRAVINQRLYFDMGTLYKS------FADYYYP 114 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 QIF E K+ D LK +Y AG++ T+ DL + ++ Sbjct: 115 QIFAKAPADP-------ELFKKIETAFDFLNTFLKGHEYAAGDSLTVADLALLASVSTFE 167 Query: 182 GTPTKKLFTERPRVNEWVAEITK-RPASEK 210 ++ P V +W A + P E+ Sbjct: 168 VASF--DISKYPNVAKWYANLKTVAPGWEE 195 >1JLV-A nrPDB Length = 209 Score = 162 bits (409), Expect = 1e-40, Method: Composition-based stats. Identities = 48/201 (23%), Positives = 76/201 (37%), Gaps = 13/201 (6%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 + + P S R V + ++ L L GEH K FL NP +P D Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTNLMAGEHMKPEFLKINPQHCIPTLVDNGF 60 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 L+ESRAI Y+A +Y + L D + A++ + + + + QI Sbjct: 61 ALWESRAICTYLAEKYG-KDDKLYPKDP---QKRAVVNQRLYFDMGTLYQRFADYYYPQI 116 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 F + AE E K+ +D L KY+AG++ T+ DL + + Sbjct: 117 FAK-------QPANAENEKKMKDAVDFLNTFLDGHKYVAGDSLTIADLTVLATVSTYDVA 169 Query: 184 PTKKLFTERPRVNEWVAEITK 204 + + P V W K Sbjct: 170 GFE--LAKYPHVAAWYERTRK 188 >1PN9-A nrPDB Length = 209 Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats. Identities = 48/206 (23%), Positives = 72/206 (34%), Gaps = 14/206 (6%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 + + P S R V + ++ L +L GEH K FL NP +P D Sbjct: 1 MDFYYLPGSAPCRAVQMTAAAVGVELNLKLTDLMKGEHMKPEFLKLNPQHCIPTLVDNGF 60 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 L+ESRAI Y+A +Y + L D + A++ + + + + QI Sbjct: 61 ALWESRAIQIYLAEKYG-KDDKLYPKDP---QKRAVVNQRLYFDMGTLYQRFADYHYPQI 116 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 F + E E K+ + L+ +Y AG T+ DL I Sbjct: 117 FAK-------QPANPENEKKMKDAVGFLNTFLEGQEYAAGNDLTIADLSLAATIATYEVA 169 Query: 184 PTKKLFTERPRVNEWVAEITK-RPAS 208 F P V W A P Sbjct: 170 GF--DFAPYPNVAAWFARCKANAPGY 193 >3M3M-A nrPDB Length = 210 Score = 155 bits (391), Expect = 1e-38, Method: Composition-based stats. Identities = 47/207 (22%), Positives = 91/207 (43%), Gaps = 13/207 (6%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M+ KV+G S ++ + L+ L +E V++ G+ + E FL++NP G++P E Sbjct: 1 MSLYKVYGDYRSGNCYKIKLMLNLLGLPYEWQAVDILGGDTQTEAFLAKNPNGKIPVLEL 60 Query: 61 GDLK-LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 D L+ES AI ++A G+ L ++ + +Q + E + +P + Sbjct: 61 EDGTCLWESNAILNFLAD-----GSQFLPSEPRLRTQ---VLQWQFFEQYSHEPYIAVAR 112 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 F Q+++ + +E + + K LDV E +L YL GE +++ D+ Sbjct: 113 FIQLYEGLPEERREEYLKLHKRGY--KALDVMEKQLSRTPYLVGEHYSIADIALYAYTH- 169 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRP 206 + + P + W+ + P Sbjct: 170 -VADEGGFDLSRYPGIQAWMQRVQSHP 195 >3M8N-A nrPDB Length = 225 Score = 153 bits (386), Expect = 6e-38, Method: Composition-based stats. Identities = 52/210 (24%), Positives = 82/210 (39%), Gaps = 14/210 (6%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M+ K++ S + +V +AL + + V V++ GE + FL++NP GQVP E Sbjct: 1 MSLYKLYSMQRSGNSYKVRLALALLDAPYRAVEVDILRGESRTPDFLAKNPSGQVPLLET 60 Query: 61 GDLK-LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDP-VASKL 118 + L ES AI Y+A GT+L + ++ M E H +P + S Sbjct: 61 APGRYLAESNAILWYLA-----VGTSLAPDTRMDRAEAL---QWMFFEQHALEPNIGSAY 112 Query: 119 AFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ 178 + + K L T E L V E LK Y A T+ D+ Sbjct: 113 FWLCLVKGGRDLQTHALEDWLERGY--AALQVMENHLKTNDYFAAGQLTIADIALYGYTH 170 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPAS 208 + + P VN W+ + + P Sbjct: 171 --VADQCDFDLSTFPAVNAWLRRVEQTPGF 198 >2C3Q-A nrPDB Length = 247 Score = 152 bits (383), Expect = 1e-37, Method: Composition-based stats. Identities = 51/206 (24%), Positives = 87/206 (42%), Gaps = 11/206 (5%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 G++++ S R V I + ++ FEL V+L G+H + F NP +VPA +DGD Sbjct: 9 GLELYLDLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGD 68 Query: 63 LKLFESRAITQYIAHRYE---NQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 L ES AI Y+ +Y+ LQ ++ A ++ L Sbjct: 69 FTLTESVAILLYLTRKYKVPDYWYPQDLQARARVDEYLAWQHTTLRR------SCLRALW 122 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK-YLAGETFTLTDLHHIPAIQ 178 + +F G +A A+L L + E + + K +L G +L DL I + Sbjct: 123 HKVMFPVFLGEPVSPQTLAATLAELDVTLQLLEDKFLQNKAFLTGPHISLADLVAITELM 182 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITK 204 + +G ++F RP++ W + Sbjct: 183 HPVGAGC-QVFEGRPKLATWRQRVEA 207 >3MAK-A nrPDB Length = 209 Score = 151 bits (381), Expect = 2e-37, Method: Composition-based stats. Identities = 43/211 (20%), Positives = 76/211 (36%), Gaps = 18/211 (8%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 + + P S R V++ ++ + L+ GEH K FL NP +P D Sbjct: 1 MVDFYYLPGSSPCRSVIMTAKAVGVELNKKLLNLQAGEHLKPEFLKINPQHTIPTLVDNG 60 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKN--ISQYAIMAIGMQVEDHQFDPVASKLAF 120 L+ESRAI Y+ +Y + + K I+Q +G + + + Sbjct: 61 FALWESRAIQVYLVEKYGKTDSLYPKCPKKRAVINQRLYFDMGTLYQS------FANYYY 114 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 Q+F E K+ + L+ Y AG++ T+ D+ + + Sbjct: 115 PQVFAKAPADP-------EAFKKIEAAFEFLNTFLEGQDYAAGDSLTVADIALVATVSTF 167 Query: 181 LGTPTKKLFTERPRVNEWVAEITK-RPASEK 210 + ++ VN W K P E+ Sbjct: 168 EVAKFE--ISKYANVNRWYENAKKVTPGWEE 196 >3IBH-A nrPDB Length = 233 Score = 150 bits (378), Expect = 5e-37, Method: Composition-based stats. Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 13/215 (6%) Query: 3 GIKVFGHPASIATRRVLIALHEKNL--DFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 + ++ PA RV IAL EKN+ + V + L GEHKK FL++N G VP E Sbjct: 18 KMIIYDTPAGPYPARVRIALAEKNMLSSVQFVRINLWKGEHKKPEFLAKNYSGTVPVLEL 77 Query: 61 GDLKLF-ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 D L E AIT+YI GT L T + + I + + E DPV+ Sbjct: 78 DDGTLIAECTAITEYID---ALDGTPTL-TGKTPLEKGVIHMMNKRAELELLDPVSVYFH 133 Query: 120 FE-QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ 178 L ++ + K + ++ L+E Y+AG++F++ D+ I Sbjct: 134 HATPGLGPEVELYQNKEWGLRQRDKALHGMHYFDTVLRERPYVAGDSFSMADI---TVIA 190 Query: 179 YLLGTPTKKLF--TERPRVNEWVAEITKRPASEKV 211 L+ KL E + W + +RP+ +K+ Sbjct: 191 GLIFAAIVKLQVPEECEALRAWYKRMQQRPSVKKL 225 >3TOT-A nrPDB Length = 226 Score = 147 bits (372), Expect = 2e-36, Method: Composition-based stats. Identities = 48/219 (21%), Positives = 85/219 (38%), Gaps = 29/219 (13%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE-DGD 62 +K+ G AS TR+V + L EK +D++ V ++ + + + F NP G+VP D Sbjct: 3 MKLIGSHASPYTRKVRVVLAEKKIDYQFVLEDVWNADTQIHQF---NPLGKVPCLVMDDG 59 Query: 63 LKLFESRAITQY------IAHRYENQGTNLLQTDSKNISQYAIMA--IGMQVEDHQFDPV 114 LF+SR I +Y +A G ++ ++ + ++VE Q P Sbjct: 60 GALFDSRVIAEYADTLSPVARLIPPSGRERVEVRCWEALADGLLDAAVALRVEQTQRTP- 118 Query: 115 ASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHI 174 E+ + + K+ + L L + + G TL D+ Sbjct: 119 ---------------EQRSESWITRQHHKIDEALKAMSRGLADRTWCNGNHLTLADIAVG 163 Query: 175 PAIQYL-LGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 A+ YL P + + + I KRP+ + Q Sbjct: 164 CALAYLDFRQPQVDWREQHANLAAFYTRIEKRPSFLETQ 202 >1E6B-A nrPDB Length = 221 Score = 145 bits (365), Expect = 2e-35, Method: Composition-based stats. Identities = 53/211 (25%), Positives = 79/211 (37%), Gaps = 14/211 (6%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 +K++ + S RV IAL K LD+E + V L G+ F NP G VPA DG Sbjct: 7 EKLKLYSYWRSSCAHRVRIALALKGLDYEYIPVNLLKGDQFDSDFKKINPMGTVPALVDG 66 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTD-SKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 D+ + +S AI Y+ +Y LL D K Y M+I + + + Sbjct: 67 DVVINDSFAIIMYLDEKYPE--PPLLPRDLHKRAVNYQAMSIVLSGIQPHQNLAVIRYIE 124 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQ 178 E+I E A + K E L K+ G+ L DL P I Sbjct: 125 EKI--------NVEEKTAWVNNAITKGFTALEKLLVNCAGKHATGDEIYLADLFLAPQIH 176 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 + + P + + + PA + Sbjct: 177 GAIN-RFQINMEPYPTLAKCYESYNELPAFQ 206 >3GX0-A nrPDB Length = 215 Score = 144 bits (364), Expect = 2e-35, Method: Composition-based stats. Identities = 46/216 (21%), Positives = 81/216 (37%), Gaps = 21/216 (9%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED-- 60 I ++ P + ++ + L E LD+ L+ V+L G + FL +P ++PA D Sbjct: 1 MIDLYFAP-TPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFLRISPNNKIPAIVDHS 59 Query: 61 -----GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVA 115 L LFES AI Y+A + G L + A + + P+ Sbjct: 60 PADGGEPLSLFESGAILLYLAEK---TGLFLSHETR----ERAATLQWLFWQVGGLGPML 112 Query: 116 SKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIP 175 + T + + + ++ V RL+ +L GE +++ D+ P Sbjct: 113 GQNHHFNHAAP----QTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYSIADIACWP 168 Query: 176 AIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKV 211 + T + P V W I RPA+ + Sbjct: 169 WVNAW--TRQRIDLAMYPAVKNWHERIRSRPATGQA 202 >5F0G-A nrPDB Length = 215 Score = 142 bits (358), Expect = 9e-35, Method: Composition-based stats. Identities = 40/211 (18%), Positives = 79/211 (37%), Gaps = 20/211 (9%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 + + P R V++ L+ + +GE K F+ NP +P D Sbjct: 1 MDFYYMPGGGGCRTVIMVAKALGLELNKKLLNTMEGEQLKPEFVKLNPQHTIPTLVDNGF 60 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNIS---QYAIMAIGMQVEDHQFDPVASKLAF 120 ++ESRAI Y+ +Y LL D K + Q +G E F Sbjct: 61 SIWESRAIAVYLVEKYGKDDY-LLPNDPKKRAVINQRLYFDMGTLYES-----------F 108 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 + + ++ T + E+ ++ + L+ +Y+AG+ T+ D+ + + Sbjct: 109 AKYYYPLFR--TGKPGSDEDLKRIETAFGFLDTFLEGQEYVAGDQLTVADIAILSTVSTF 166 Query: 181 LGTPTKKLFTERPRVNEWVAEITK-RPASEK 210 + + F++ V+ W K P ++ Sbjct: 167 EVS--EFDFSKYSNVSRWYDNAKKVTPGWDE 195 >1G6W-A nrPDB Length = 261 Score = 142 bits (357), Expect = 1e-34, Method: Composition-based stats. Identities = 54/241 (22%), Positives = 94/241 (39%), Gaps = 31/241 (12%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 + G +F H ++ +V I L E + + ++ GEH+ F+S NP +VPA D Sbjct: 18 LEGYTLFSHRSAPNGFKVAIVLSELGFHYNTIFLDFNLGEHRAPEFVSVNPNARVPALID 77 Query: 61 ---GDLKLFESRAITQYIAHRYENQ-GTNLLQ----TDSKNISQYAIMA-------IGMQ 105 +L ++ES AI ++ ++Y + G LL D I+ + IG Sbjct: 78 HGMDNLSIWESGAILLHLVNKYYKETGNPLLWSDDLADQSQINAWLFFQTSGHAPMIGQA 137 Query: 106 VEDHQFDPVASKLAFEQIFKSIYGL-TTDEAVVAEEEAKLAKVLD-------------VY 151 + F A E+ + + E +AE L LD + Sbjct: 138 LHFRYFHSQKIASAVERYTDEVRRVYGVVEMALAERREALVMELDTENAAAYSAGTTPMS 197 Query: 152 EARLKEFK-YLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 ++R ++ +L G+ T+ DL +P + P V +W + +RPA K Sbjct: 198 QSRFFDYPVWLVGDKLTIADLAFVPWNNVVDRIGINIKIE-FPEVYKWTKHMMRRPAVIK 256 Query: 211 V 211 Sbjct: 257 A 257 >3GH6-A nrPDB Length = 210 Score = 141 bits (354), Expect = 3e-34, Method: Composition-based stats. Identities = 40/209 (19%), Positives = 73/209 (34%), Gaps = 15/209 (7%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHV-ELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 + ++ P S R VL+ ++F+ + + E +L NP +P D Sbjct: 1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHG 60 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 L+ESRAI Y+ +Y K++ + A++ + + S+ + Q Sbjct: 61 FALWESRAIMVYLVEKYGKDDKLF----PKDVQKQALINQRLYFDMGTLYKSFSEYYYPQ 116 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 IF + E K+ + L+ Y AG ++L D+ + + Sbjct: 117 IFLK-------KPANEENYKKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVSTFDV 169 Query: 183 TPTKKLFTERPRVNEWVAEITKR-PASEK 210 F V W K P E+ Sbjct: 170 AGF--DFKRYANVARWYENAKKLTPGWEE 196 >2JL4-A nrPDB Length = 213 Score = 139 bits (350), Expect = 8e-34, Method: Composition-based stats. Identities = 52/213 (24%), Positives = 93/213 (43%), Gaps = 13/213 (6%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 +K++ S + R+ IAL+ K + +E + V L EH K+ F + NP VPA + G Sbjct: 1 KMKLYNFWRSGTSHRLRIALNLKGVPYEYLAVHLGKEEHLKDAFKALNPQQLVPALDTGA 60 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 L +S AI +++ +Y LL D+ + +A + + H P+ ++ E Sbjct: 61 QVLIQSPAIIEWLEEQYPTPA--LLPADADGRQRVRALAAIVGCDIH---PINNRRILEY 115 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARL----KEFKYLAGETFTLTDLHHIPAIQ 178 + K+ + A+ A ++ D YEA L K +Y G+T TL D + +P ++ Sbjct: 116 LRKTFGA--DEAAINAWCGTWISAGFDAYEALLAVDPKRGRYSFGDTPTLADCYLVPQVE 173 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEKV 211 + T P + A + A + Sbjct: 174 S--ARRFQVDLTPYPLIRAVDAACGELDAFRRA 204 >3LSZ-A nrPDB Length = 225 Score = 139 bits (349), Expect = 1e-33, Method: Composition-based stats. Identities = 62/220 (28%), Positives = 92/220 (41%), Gaps = 25/220 (11%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHV---ELKDGEHKKEP--------FLSRNP 51 +K++G S A+R + + L E +L FE V V H E +L+ NP Sbjct: 2 SLKIYGVYRSRASRPLWL-LAELDLPFEHVPVIQANRVAHPHGPEAPLNTASAAYLAVNP 60 Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 GQ+P E+ L L ES AIT +IA QG L ++ + A+M Sbjct: 61 LGQIPCLEEEGLILTESLAITLHIAR---TQGGQL---GPRSEPEDALMVSWSLFAATAV 114 Query: 112 DPVASKLAFEQIFKSIYGLTTDE--AVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLT 169 +P A ++ Q+ + G T+ E A +A +L + L E YL G FT+ Sbjct: 115 EPPALEI---QLIQRSGGGTSPEGQAAIAIAAERLRRPLARLERHFAAEDYLVGGRFTVA 171 Query: 170 DLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 DL+ ++Y G L P V W+ RPA Sbjct: 172 DLNLAETLRY--GQAHPALLEPFPAVAAWLDRCQSRPAFR 209 >2PMT-A nrPDB Length = 203 Score = 136 bits (342), Expect = 7e-33, Method: Composition-based stats. Identities = 48/205 (23%), Positives = 83/205 (40%), Gaps = 18/205 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELK-DGEHKKEPFLSRNPFGQVPAFE-DG 61 +K++ P S + I L E LDF + ++L+ + FL+ NP GQVP + D Sbjct: 1 MKLYYTPGSCSLSP-HIVLRETGLDFSIERIDLRTKKTESGKDFLAINPKGQVPVLQLDN 59 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L E AI QY+A L+ D I+ + Q+E F Sbjct: 60 GDILTEGVAIVQYLAD---------LKPDRNLIAPPKALERYHQIEWLNF----LASEVH 106 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + + ++ T E+ + + KL L + K + G+ FT+ D + Q+ Sbjct: 107 KGYSPLFSSDTPESYLPVVKNKLKSKFVYINDVLSKQKCVCGDHFTVADAYLFTLSQW-- 164 Query: 182 GTPTKKLFTERPRVNEWVAEITKRP 206 T+ + +++A I +RP Sbjct: 165 APHVALDLTDLSHLQDYLARIAQRP 189 >3C8E-A nrPDB Length = 288 Score = 136 bits (342), Expect = 8e-33, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 91/229 (39%), Gaps = 39/229 (17%) Query: 3 GIKVFGHPASIATRRVLIALHEK------NLDFELVHVELKDGEHKKEPFLSRNPFGQVP 56 ++++ + ++V I L E +++ + + DG+ F+ NP ++P Sbjct: 44 PLQLYSL-GTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP 102 Query: 57 AFEDG----DLKLFESRAITQYIAHRYENQGTNLLQTDSKN------ISQYAIMAIGMQV 106 A D +++FES +I Y+A ++ L ++ + A G Sbjct: 103 ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGGFG 162 Query: 107 EDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETF 166 + + PV + A + + ++LDV + +L + K++AG+ + Sbjct: 163 HFYHYAPVKIEYAINRFTM-----------------EAKRLLDVLDKQLAQHKFVAGDEY 205 Query: 167 TLTDLHHIPAIQYLL--GTPTKKLFTE---RPRVNEWVAEITKRPASEK 210 T+ D+ P ++ G F + V W E+ +RPA ++ Sbjct: 206 TIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKR 254 >3LFL-A nrPDB Length = 240 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 46/209 (22%), Positives = 81/209 (38%), Gaps = 21/209 (10%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 I+++ R + L K + E++++ LK +K E F +NPFG VP E+ Sbjct: 22 GSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLK---NKPEWFFKKNPFGLVPVLENS 78 Query: 62 DLKLFESRAI-TQYIAHRYENQGTNLLQTDS-KNISQYAIMAIGMQVEDHQFDPVASKLA 119 +L AI +Y+ Y G LL D + Q I+ + +V + S+ Sbjct: 79 QGQLIYESAITCEYLDEAYP--GKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQ-- 134 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 D A + EE K L+V K+ + G + ++ D P + Sbjct: 135 ----------NKEDYAGLKEEFRKEFTKLEVLTN--KKTTFFGGNSISMIDYLIWPWFER 182 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPAS 208 L + P++ W+A + + P Sbjct: 183 LEAMKLNECVDHTPKLKLWMAAMKEDPTV 211 >4IKH-A nrPDB Length = 244 Score = 130 bits (327), Expect = 4e-31, Method: Composition-based stats. Identities = 52/215 (24%), Positives = 85/215 (39%), Gaps = 21/215 (9%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG-- 61 I+++ P + +V I L E L +E V + + FLS +P ++PA D Sbjct: 23 IQLYSLP-TPNGVKVSIMLEEIGLPYEAHRVSFETQDQMTPEFLSVSPNNKIPAILDPHG 81 Query: 62 ----DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASK 117 L LFES AI Y+A + G L Q + + + P+ + Sbjct: 82 PGDQPLALFESGAILIYLADK---SGQLLAQESAARYE----TIQWLMFQMGGIGPMFGQ 134 Query: 118 LAFEQIFKSIYGLTTDEAVVAEEEAKLAK-VLDVYEARLKEFKYLAGETFTLTDLHHIPA 176 + F F G ++ E AK +L V + L +++ GE +T+ D+ P Sbjct: 135 VGF---FNKFAGREYEDKRPLERYVNEAKRLLGVLDKHLGGREWIMGERYTIADIATFPW 191 Query: 177 IQYLLGTPTKKLF---TERPRVNEWVAEITKRPAS 208 I+ L+G P V +A+ RPA Sbjct: 192 IRNLIGFYEAGELVGIDNFPEVKRVLAKFVARPAV 226 >4MDC-A nrPDB Length = 252 Score = 129 bits (325), Expect = 7e-31, Method: Composition-based stats. Identities = 45/216 (20%), Positives = 88/216 (40%), Gaps = 20/216 (9%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLK 64 ++ HP S A+R V + L E EL E + E+++ FL+ NP G +P + D ++ Sbjct: 25 TLYHHPMSPASRFVRLILSEYGYQTELS--EEQPWENRR-DFLTLNPAGTLPVYVDDSMR 81 Query: 65 -LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF-----DPVASKL 118 L + I++Y+ + +++ D + +++ ++ F V L Sbjct: 82 ALCGATIISEYLDE-----TSGIMKRDRRLLAEDPFQRAEIRRLTEWFLQKMEADVTRPL 136 Query: 119 AFEQIFKSIY-----GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHH 173 E+IFK G D ++ + + + + +LAG+ + DL Sbjct: 137 VRERIFKLQMTPDQGGGAPDSKILRTSRSNIRQHMKYLSWLAGSRPWLAGDRISYGDLAA 196 Query: 174 IPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 AI L + +++ P EW + RP+ Sbjct: 197 AAAISVL-DYLGEIDWSDAPTAKEWYQRLKSRPSFR 231 >1F2E-A nrPDB Length = 201 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 48/207 (23%), Positives = 81/207 (39%), Gaps = 18/207 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELK-DGEHKKEPFLSRNPFGQVPAFE-DG 61 +K+F P + + IAL E DFE V V+L E FL+ NP G+VPA D Sbjct: 1 MKLFISPGA-CSLAPHIALRETGADFEAVKVDLAVRKTEAGEDFLTVNPSGKVPALTLDS 59 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L E+ AI YIA + G L ++ +Y +++ + F Sbjct: 60 GETLTENPAILLYIADQNPASG---LAPAEGSLDRYRLLSRLSFLGSE----------FH 106 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + F ++ T + A + L + L + AG F++ D++ + + Sbjct: 107 KAFVPLFAPATSDEAKAAAAESVKNHLAALDKELAGRDHYAGNAFSVADIYLYVMLGWP- 165 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPAS 208 P + + +I +RPA Sbjct: 166 -AYVGIDMAAYPALGAYAGKIAQRPAV 191 >4MK3-A nrPDB Length = 226 Score = 127 bits (318), Expect = 4e-30, Method: Composition-based stats. Identities = 39/208 (18%), Positives = 74/208 (35%), Gaps = 13/208 (6%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE-DG 61 +K++ S R+V + L EK +D+E++ + + F NP G+VP + Sbjct: 22 SMKLYASQTSPYARKVRVVLAEKKIDYEMIEENVWSPDTTIGRF---NPLGKVPCLVMED 78 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 +F+SR I +Y L+ S+ + ++ Sbjct: 79 GGAVFDSRVIAEYADTLSPVS--RLIPQGSRERLEVRCWEALADGLLDAALLARLEVTQR 136 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL- 180 + E+ V + +K+ L L + + G +TL D+ A+ YL Sbjct: 137 K------ESERSESWVQRQRSKIDAALTAMSTGLADKTWCTGTHYTLADVAVGCALAYLD 190 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPAS 208 P P + + +I KR + Sbjct: 191 FRFPDIAWRDRHPNLVAFQEKIEKRQSF 218 >4PXO-A nrPDB Length = 238 Score = 126 bits (317), Expect = 6e-30, Method: Composition-based stats. Identities = 52/217 (23%), Positives = 84/217 (38%), Gaps = 16/217 (7%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 + +K++G+ S A RV IAL+ K + +E V ++L G+ K FL+ NP G VPA DG Sbjct: 22 SMVKMYGNWRSAAAFRVRIALNLKGIAYEEVFLDLDAGDQHKPDFLAINPQGAVPALFDG 81 Query: 62 DL-KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 D L +S AI Y+ G LL + + ++ +A + + H + Sbjct: 82 DGPPLTQSLAILDYLEE--TRTGVPLLPEEPRARARARSLAQVVACDTHPLY-----VPR 134 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF----KYLAGETFTLTDLHHIPA 176 + F E ++ L E RL ++ G+ + DL I Sbjct: 135 VRTFLMENYGLPRERMLEFLRNAFITGLKTLETRLSNEAGTGRFCQGDAVSHADLCLISL 194 Query: 177 IQYLLGTPT-KKLFTERPRVNEWVAEITKRPASEKVQ 212 +GT P V E+ A + Sbjct: 195 ---WVGTGIFGIDTAAYPTVKRISEEVLALDAVARAH 228 >4QQ7-A nrPDB Length = 207 Score = 126 bits (316), Expect = 8e-30, Method: Composition-based stats. Identities = 49/217 (22%), Positives = 91/217 (41%), Gaps = 30/217 (13%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 + + ++ ++R + L EK +DFE+ V+L +K E NP+GQVP + Sbjct: 4 SMMVLYSGTTCPFSQRCRLVLFEKGMDFEIRDVDLF---NKPEDISVMNPYGQVPILVER 60 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 DL L+ES I +YI R+ + L+ D ++ + + + E Sbjct: 61 DLILYESNIINEYIDERFPH--PQLMPADPVQRARARLFLLNFEKE-------------- 104 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKE-------FKYLAGETFTLTDLHHI 174 +F + L ++ AE+ + A++ RL + KY+ GE F++ D+ Sbjct: 105 -LFVHVSTLENEKGKAAEKNHEKARL--AIRDRLTQLAPIFVKNKYMLGEEFSMLDVAIA 161 Query: 175 PAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKV 211 P + L + P + ++ I RPA + Sbjct: 162 PLLWRLDHYGIELSKNAAP-LMKYAERIFSRPAYIEA 197 >3UBL-A nrPDB Length = 242 Score = 123 bits (308), Expect = 6e-29, Method: Composition-based stats. Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 15/180 (8%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M IK+ G S +V + + EK L++E + + ++E FL +P G++P E Sbjct: 1 MVMIKLHGASISNYVNKVKLGILEKGLEYEQIRI----APSQEEDFLKISPMGKIPVLEM 56 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +FES AI +++ + Q L+ D ++ I +E + P Sbjct: 57 DGKFIFESGAILEFLDTIFP-QTPKLIPEDPWEAARVR--EISTIIETYLDIPARRIY-- 111 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 + +V E + L K + + ++ Y+AG FTL D + L Sbjct: 112 ------LPAAKVSPEIVEEVHSTLVKGIKALQRVVRFSPYIAGNVFTLADCSGFAHLSVL 165 >2CZ2-A nrPDB Length = 223 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 41/195 (21%), Positives = 79/195 (40%), Gaps = 19/195 (9%) Query: 6 VFGHPASIATRRVLIALHEKNLDFELVHVELKD--GEHKKEPFLSRNPFGQVPAFEDGDL 63 ++ + S + RV IAL K +D+E+V + L G+ E F + NP QVPA + + Sbjct: 15 LYSYFRSSCSWRVRIALALKGIDYEIVPINLIKDGGQQFTEEFQTLNPMKQVPALKIDGI 74 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 + +S AI +Y+ LL D + AI+ + + P+ + +Q+ Sbjct: 75 TIVQSLAIMEYLEETRPI--PRLLPQDP---QKRAIVRMISDLIASGIQPLQNLSVLKQV 129 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYLL 181 E + + + + E L+ KY G+ ++ D+ +P + Sbjct: 130 --------GQENQMQWAQKVITSGFNALEKILQSTAGKYCVGDEVSMADVCLVPQVAN-- 179 Query: 182 GTPTKKLFTERPRVN 196 K + P ++ Sbjct: 180 AERFKVDLSPYPTIS 194 >1N2A-A nrPDB Length = 201 Score = 121 bits (303), Expect = 3e-28, Method: Composition-based stats. Identities = 48/210 (22%), Positives = 85/210 (40%), Gaps = 18/210 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGE-HKKEPFLSRNPFGQVPAFEDGD 62 +K+F P + + I L E DF LV V+L + + + NP GQVPA D Sbjct: 1 MKLFYKPGA-CSLASHITLRESGKDFTLVSVDLMKKRLENGDDYFAVNPKGQVPALLLDD 59 Query: 63 LKLF-ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L E AI QY+A ++ L +IS+Y + + +A++L Sbjct: 60 GTLLTEGVAIMQYLADSVPDRQ---LLAPVNSISRYKTIE--------WLNYIATEL--H 106 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + F ++ T E A+L K L LK+ ++ G+ FT+ D + +++ Sbjct: 107 KGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFTVLRWAY 166 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKV 211 + ++ + +RP + Sbjct: 167 AVKLN--LEGLEHIAAFMQRMAERPEVQDA 194 >1FW1-A nrPDB Length = 216 Score = 121 bits (302), Expect = 3e-28, Method: Composition-based stats. Identities = 41/208 (19%), Positives = 79/208 (37%), Gaps = 19/208 (9%) Query: 6 VFGHPASIATRRVLIALHEKNLDFELVHVELKD--GEHKKEPFLSRNPFGQVPAFEDGDL 63 ++ + S + RV IAL K +D++ V + L G+ + F + NP QVP + + Sbjct: 8 LYSYFRSSCSWRVRIALALKGIDYKTVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGI 67 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 + +S AI +Y+ LL D K A + + + P+ + +Q+ Sbjct: 68 TIHQSLAIIEYLEETRPT--PRLLPQDPKK---RASVRMISDLIAGGIQPLQNLSVLKQV 122 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK--YLAGETFTLTDLHHIPAIQYLL 181 +E + + + + E L+ Y G+ T+ DL +P + Sbjct: 123 --------GEEMQLTWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVAN-- 172 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASE 209 K T P ++ + A + Sbjct: 173 AERFKVDLTPYPTISSINKRLLVLEAFQ 200 >3UAR-A nrPDB Length = 227 Score = 119 bits (298), Expect = 9e-28, Method: Composition-based stats. Identities = 49/209 (23%), Positives = 87/209 (41%), Gaps = 19/209 (9%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKE-PFLSRNPFGQVPAFE-DG 61 +K++ P + + I L E LDFEL +V+L + FL NP G VPA + D Sbjct: 3 MKLYYFPGA-CSLAPHIVLREAGLDFELENVDLGTKKTGSGADFLQVNPKGYVPALQLDD 61 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L E + I QY+A G L S +Y ++ +++++ Sbjct: 62 GQVLTEDQVILQYLADLKPESG---LMPPSGTFERYRLLE--------WLAFISTEI--H 108 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARL-KEFKYLAGETFTLTDLHHIPAIQYL 180 + F + + EA L++ LD E RL +L G+ +++ D + + + Sbjct: 109 KTFGPFWNPESPEASKQIALGLLSRRLDYVEDRLEAGGPWLMGDRYSVADAYLSTVLGWC 168 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPASE 209 K ++ PR+ ++ RPA + Sbjct: 169 E--YLKIDLSKWPRILAYLERNQARPAVQ 195 >2GDR-A nrPDB Length = 202 Score = 116 bits (290), Expect = 7e-27, Method: Composition-based stats. Identities = 42/208 (20%), Positives = 83/208 (39%), Gaps = 18/208 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKK-EPFLSRNPFGQVPAFE-DG 61 +K++ P + + IAL E L+FELV V+L + + +L NP G VP + D Sbjct: 1 MKLYYSPGACSLSP-HIALREAGLNFELVQVDLASKKTASGQDYLEVNPAGYVPCLQLDD 59 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 L E AI QY+A + + L + + +Y + + ++S+L Sbjct: 60 GRTLTEGPAIVQYVADQVPGKQ---LAPANGSFERYHL--------QQWLNFISSEL--H 106 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 + F ++ + + L L +L+ YL G+ ++ D++ + + Sbjct: 107 KSFSPLFNPASSDEWKNAVRQSLNTRLGQVARQLEHAPYLLGDQLSVADIYLFVVLGW-- 164 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASE 209 + P + + + R A + Sbjct: 165 SAYVNIDLSPWPSLQAFQGRVGGREAVQ 192 >1V2A-A nrPDB Length = 210 Score = 110 bits (274), Expect = 5e-25, Method: Composition-based stats. Identities = 41/211 (19%), Positives = 73/211 (34%), Gaps = 22/211 (10%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 + + S + ++ + + L + D + + NP +P D Sbjct: 1 MDYYYSLISPPCQSAILLAKKLGITLNLKKTNVHDPVER-DALTKLNPQHTIPTLVDNGH 59 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNIS---QYAIMAIGMQVEDHQFDPVASKLAF 120 ++ES AI Y+ Y T L D K S Q IG + Sbjct: 60 VVWESYAIVLYLVETYAKDDT-LYPKDPKVRSVVNQRLFFDIGTL--------------Y 104 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 ++I I+ + E E+ KL LD+ E + E Y A + T+ D+ + + L Sbjct: 105 KRIIDVIHLVMKKEQPSDEQMEKLKGALDLLEQFVTERAYAAADHLTVADICLLGTVTAL 164 Query: 181 LGTPTKKLFTERPRVNEWVAEIT-KRPASEK 210 K P + W+ + + P E+ Sbjct: 165 --NWLKHDLEPFPHIRAWLERVRAEMPDYEE 193 >5NR1-A nrPDB Length = 228 Score = 109 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 44/210 (20%), Positives = 77/210 (36%), Gaps = 13/210 (6%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED---- 60 + P A+R+V +AL EK L F + V F S NP G P + Sbjct: 6 TLHHFPLDPASRQVRLALGEKRLPFVEMQVRYW---EMPPEFTSLNPSGMPPVLVETKHQ 62 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +L + E+RAI ++I LL D ++ + + + V L Sbjct: 63 RNLVICETRAILEHIEE--TETEPPLLGRDPAERAEARRLLQWFDRKF--DNEVNGFLLH 118 Query: 121 EQIFKSIYGLT-TDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 E++ K + + D A + + L L E+ L+ +LAG +L D + Sbjct: 119 EKMEKRLLRMGAPDLAALRQGREALRMHLGYIESLLQTRDWLAGRRMSLADFAAAAHLS- 177 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPASE 209 ++ + + W ++ RP Sbjct: 178 VIDYFGDVPWKDFQAAKTWYMKLKSRPCFR 207 >3QAG-A nrPDB Length = 239 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 79/208 (37%), Gaps = 17/208 (8%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 I+++ + R + L K++ E+V++ L+ +K E + +++PFG +P E Sbjct: 22 GLIRIYSMRFCPYSHRTRLVLKAKDIRHEVVNINLR---NKPEWYYTKHPFGHIPVLETS 78 Query: 62 DLKLFESRAI-TQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +L I +Y+ Y G L D ++ ++ H L Sbjct: 79 QSQLIYESVIACEYLDDAYP--GRKLFPYDPYERARQKMLLELFSKVPHLTKECLVAL-- 134 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 +S T +A + +E + L ++L+ + + G + ++ D P + L Sbjct: 135 ----RSGRESTNLKAALRQEFSNLEEILEY-----QNTTFFGGTSISMIDYLLWPWFERL 185 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPAS 208 + P + W++ + P Sbjct: 186 DVYGILDCVSHTPALRLWISAMKWDPTV 213 >4IGJ-A nrPDB Length = 242 Score = 104 bits (259), Expect = 3e-23, Method: Composition-based stats. Identities = 40/200 (20%), Positives = 79/200 (39%), Gaps = 18/200 (9%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAF---ED 60 ++++ + S + RV + L K L +E V+L E + +RNP QVP ED Sbjct: 25 LRLYSYWRSSSAWRVRLGLALKGLAYEYRAVDLLAQEQFQAAHQARNPMSQVPVLEVEED 84 Query: 61 G-DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 G L +S AI +++ R+ LL D ++ +A + + P+ + L Sbjct: 85 GRTHLLVQSMAILEWLEERHPEPA--LLPPDLWGRARVRALA---EHVNSGTQPMQNALV 139 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKE--FKYLAGETFTLTDLHHIPAI 177 + + + G + +A+ L E +++ ++ G+ TL D + +P + Sbjct: 140 LRMLREKVPGWDRE-----WARFFIARGLAALETAVRDGAGRFSHGDAPTLADCYLVPQL 194 Query: 178 QYLLGTPTKKLFTERPRVNE 197 P + Sbjct: 195 YN--ARRFGLDLEPYPTLRR 212 >5D9W-A nrPDB Length = 230 Score = 104 bits (258), Expect = 4e-23, Method: Composition-based stats. Identities = 43/207 (20%), Positives = 74/207 (35%), Gaps = 35/207 (16%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLF-ESRA 70 S ++RVL+ L EK + +E+ +++ ++K + FL +P G+VP F GD K +S Sbjct: 37 SPFSQRVLLTLEEKKVPYEMKLIDV---QNKPDWFLKISPEGKVPVFNGGDGKWIPDSDV 93 Query: 71 ITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGL 130 ITQ I +Y P +IF Sbjct: 94 ITQVIEEKYPTPS--------------------------LVTPPEYASVGSKIFSCFTTF 127 Query: 131 TTDEAVVAEEEAKLAKVLDVYEARLKEF-KYLAGETFTLTDLHHIPAIQYLLGT----PT 185 + E L L E LK ++ G+ + DL P + +L Sbjct: 128 LKSKDPNDGSEKALLTELQALEEHLKAHGPFINGQNISAADLSLAPKLYHLQVALEHFKG 187 Query: 186 KKLFTERPRVNEWVAEITKRPASEKVQ 212 K+ + V+ + + R + K + Sbjct: 188 WKIPEDLTNVHAYTEALFSRESFIKTK 214 >3NIV-A nrPDB Length = 222 Score = 104 bits (258), Expect = 4e-23, Method: Composition-based stats. Identities = 45/212 (21%), Positives = 78/212 (36%), Gaps = 15/212 (7%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKD--GEHKKEPFLSRNPFGQVPAFED 60 + ++ + S A RV IAL+ K + +E + V L + GE + NP VP+ + Sbjct: 2 SLILYDYFRSTACYRVRIALNLKKIAYEKIEVHLVNNGGEQHSLQYHQINPQELVPSLDI 61 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 L +S AI Y+ + LL D + MA+ + + H + + Sbjct: 62 NGQILSQSMAIIDYLEEIHPE--MPLLPKDPFMKATLKSMALIVACDMHPLNNLRVLNRL 119 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARL----KEFKYLAGETFTLTDLHHIPA 176 ++ F + +E V+ L D +E +L ++ G L D+ IP Sbjct: 120 KEQFNA-----NEEQVLEWYHHWLKTGFDAFEEKLGALERDKPVCFGSEVGLADVCLIPQ 174 Query: 177 IQYLLGTPTKKLFTERPRVNEWVAEITKRPAS 208 + P +NE PA Sbjct: 175 VYN--AHRFHFDMASYPIINEINEYCLTLPAF 204 >4J2F-A nrPDB Length = 223 Score = 102 bits (254), Expect = 1e-22, Method: Composition-based stats. Identities = 39/216 (18%), Positives = 73/216 (33%), Gaps = 29/216 (13%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-QVPAFEDGD 62 +K+ G S + RV+ AL K + +E V +L +K L NP ++P G Sbjct: 5 LKLHGAWPSPFSCRVIWALKLKGIPYEYVEEDLF---NKSPLLLQYNPVHKKIPVLVHGG 61 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES I +Y+ + LL +D + ++ + + E Sbjct: 62 KPICESTIILEYLDETWPE--NPLLPSDPHERAVARFWVKFIEDKGTAIWNIFRTKGEEL 119 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEAR---LKEFKYLAGETFTLTDLH---HIPA 176 E V VL E + + KY G+ + D+ Sbjct: 120 -----------EKAVKNCLE----VLKTIEEHAMGVSDDKYFGGDKIGIVDIAFCGIAHW 164 Query: 177 IQYLLGTPTKKLFT--ERPRVNEWVAEITKRPASEK 210 + + K+ + PR++ W + P ++ Sbjct: 165 LGVIEEVAGVKVLESQKFPRLHAWTENFKEAPIIKE 200 >4CHS-A nrPDB Length = 219 Score = 100 bits (250), Expect = 3e-22, Method: Composition-based stats. Identities = 43/211 (20%), Positives = 79/211 (37%), Gaps = 22/211 (10%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-QVPAFEDGD 62 + + S RV IAL EK +++E +L+ +K L NP ++P Sbjct: 5 VVLLDFWPSPFGMRVRIALAEKGIEYEYKEEDLR---NKSPLLLQMNPVHKKIPVLIHNG 61 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES QYI + ++ LL +D +Q A + ++ H Sbjct: 62 KPISESLIAVQYIEEVWNDR-NPLLPSDPYQRAQARFWADYVDIKIHDLG---------- 110 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIP---AIQY 179 K I+ +E A++E + L + E +L + Y G+ D+ +P + Sbjct: 111 --KKIWTSKGEEKEAAKKE--FIEALKLLEEQLGDKTYFGGDNIGFVDIALVPFYTWFKV 166 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 + + E PR W ++ + K Sbjct: 167 YETFGSLNIENECPRFVAWAKRCLQKESVAK 197 >5IQY-A nrPDB Length = 216 Score = 99.8 bits (247), Expect = 7e-22, Method: Composition-based stats. Identities = 47/210 (22%), Positives = 75/210 (35%), Gaps = 41/210 (19%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLF-ESRA 70 ++RVL+ L EK + +E+ V+L +K E FL +P G+VP F GD K +S Sbjct: 23 CPFSQRVLLTLEEKKITYEMKLVDLS---NKPEWFLKISPEGKVPVFNSGDGKWIADSDV 79 Query: 71 ITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGL 130 ITQ I ++ P +IF S Sbjct: 80 ITQVIEEKFPTPS--------------------------LVTPPEYASVGSKIFPSFVKF 113 Query: 131 TTDEAVVAEEEAKLAKVLDVYEARLKEF-KYLAGETFTLTDLHHIP-------AIQYLLG 182 + E L L + LK Y++GE + DL P A+++ G Sbjct: 114 LKSKDASDGSEKALLDELQALDEHLKAHGPYISGENVSAADLSLGPKLFHLQVALEHFKG 173 Query: 183 TPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 + T V+ + + R + K + Sbjct: 174 WKIPENLTS---VHAYTKALFSRESFVKTK 200 >2VO4-A nrPDB Length = 219 Score = 97.9 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 40/212 (18%), Positives = 75/212 (35%), Gaps = 24/212 (11%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-QVPAFEDGD 62 + + S RV IAL EK + +E +L+ +K L NP ++P Sbjct: 5 VVLLDFWPSPFGMRVRIALAEKGIKYEYKEEDLR---NKSPLLLQMNPVHKKIPVLIHNG 61 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES QYI + ++ LL +D +Q + ++ Sbjct: 62 KPICESLIAVQYIEEVWNDR-NPLLPSDPYQRAQTRFW---------------ADYVDKK 105 Query: 123 IFKSIYGLTTDEAVVAEEEAKLA-KVLDVYEARLKEFKYLAGETFTLTDLHHIP---AIQ 178 I+ + T + E K + L + E +L + Y G+ D+ +P + Sbjct: 106 IYDLGRKIWTSKGEEKEAAKKEFIEALKLLEEQLGDKTYFGGDNLGFVDIALVPFYTWFK 165 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 T + +E P+ W ++ + K Sbjct: 166 AYETFGTLNIESECPKFIAWAKRCLQKESVAK 197 >3LG6-A nrPDB Length = 235 Score = 96.7 bits (239), Expect = 6e-21, Method: Composition-based stats. Identities = 41/224 (18%), Positives = 79/224 (35%), Gaps = 22/224 (9%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE-- 59 +++G+ S + R+ IA H K++ + V L GE + + S NP VP Sbjct: 8 PNFELYGYFRSSCSGRLRIAFHLKSIPYTRHPVNLLKGEQHSDTYKSLNPTNTVPLLVVS 67 Query: 60 ---------DGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQ 110 + +S A +Y+ LL S +++ + I + Sbjct: 68 NINNTVSPSSASFSIGQSLAALEYLEEALPTNARPLLPPISNPVARAHVRTICNIIAC-- 125 Query: 111 FDPVASKLAFEQIFKSIYGLTT--DEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTL 168 + L ++ K++ G T + + + K+L+ L ++ G+ TL Sbjct: 126 DVQPVTNLKIQKKVKALDGDPTVWSRDLATQGFGAVEKLLE-----LSAGRFCVGDEITL 180 Query: 169 TDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 D+ +PA+ P E+ K A +K Sbjct: 181 ADVCLVPAVWAAERVGM--DLARFPITKRVFEEMLKEEAVQKAH 222 >5ELG-A nrPDB Length = 221 Score = 96.0 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 40/207 (19%), Positives = 73/207 (35%), Gaps = 35/207 (16%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 ++R L+ L EK+L +++ + L D K + FL +P G+VP + D + +S I Sbjct: 20 CPFSQRALLTLEEKSLTYKIHLINLSD---KPQWFLDISPQGKVPVLKIDDKWVTDSDVI 76 Query: 72 TQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLT 131 + +Y + P IF + Sbjct: 77 VGILEEKYPDPPLK--------------------------TPAEFASVGSNIFGTFGTFL 110 Query: 132 TDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYL-LGTPTKKL 188 + E L L+ E LK ++AGE + DL P + +L + K Sbjct: 111 KSKDSNDGSEHALLVELEALENHLKSHDGPFIAGERVSAVDLSLAPKLYHLQVALGHFKS 170 Query: 189 F---TERPRVNEWVAEITKRPASEKVQ 212 + P V+ ++ + + EK + Sbjct: 171 WSVPESFPHVHNYMKTLFSLDSFEKTK 197 >6JWK-A nrPDB Length = 222 Score = 95.6 bits (236), Expect = 1e-20, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 67/157 (42%), Gaps = 8/157 (5%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 ++++ S + RV IAL K LD+++V V L+ GE + RNP G +P D D Sbjct: 1 MQLYSFFNSSTSYRVRIALALKGLDYQVVPVNLRQGEQLRPADRQRNPMGALPTLVDADG 60 Query: 64 KLF-ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + F +S AI Y+ L+ D + +Q +A+ + + H P+ + + Sbjct: 61 RRFSQSLAIIDYLDAVQPE--PRLIPLDPLHRAQALELALLVACDIH---PLNNVRVLKY 115 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK 159 + + + D +A+ L E L + Sbjct: 116 LTQVLGIDAEDRQ--RWYAHWVAEGLAAAETLLNRHR 150 >1B8X-A nrPDB Length = 280 Score = 94.0 bits (232), Expect = 4e-20, Method: Composition-based stats. Identities = 38/159 (23%), Positives = 69/159 (43%), Gaps = 19/159 (11%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P + DGD+KL +S AI +YIA ++ G + ++ + A++ I V Sbjct: 51 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 105 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL YL G+ T D Sbjct: 106 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDF 152 Query: 172 HHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 A+ +L P++ + I P +K Sbjct: 153 MLYDALDVVLYM-DPMCLDAFPKLVCFKKRIEAIPQIDK 190 >1BG5-A nrPDB Length = 254 Score = 94.0 bits (232), Expect = 4e-20, Method: Composition-based stats. Identities = 38/159 (23%), Positives = 69/159 (43%), Gaps = 19/159 (11%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P + DGD+KL +S AI +YIA ++ G + ++ + A++ I V Sbjct: 52 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 106 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL YL G+ T D Sbjct: 107 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDF 153 Query: 172 HHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 A+ +L P++ + I P +K Sbjct: 154 MLYDALDVVLYM-DPMCLDAFPKLVCFKKRIEAIPQIDK 191 >1DUG-A nrPDB Length = 234 Score = 93.7 bits (231), Expect = 5e-20, Method: Composition-based stats. Identities = 38/159 (23%), Positives = 69/159 (43%), Gaps = 19/159 (11%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P + DGD+KL +S AI +YIA ++ G + ++ + A++ I V Sbjct: 51 FPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 105 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL YL G+ T D Sbjct: 106 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDF 152 Query: 172 HHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 A+ +L P++ + I P +K Sbjct: 153 MLYDALDVVLYM-DPMCLDAFPKLVCFKKRIEAIPQIDK 190 >5J5N-A nrPDB Length = 231 Score = 93.7 bits (231), Expect = 6e-20, Method: Composition-based stats. Identities = 40/212 (18%), Positives = 73/212 (34%), Gaps = 22/212 (10%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNP-FGQVPAFEDGD 62 + + S RV +AL EK + +E +L + L NP Q+P Sbjct: 17 VTLLDFWPSPFGMRVRLALAEKGVKYEYSEEDLWNKSAL---LLQMNPVNKQIPVLVHNG 73 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES I QYI +++ LL +D +Q D + + K+ ++ Sbjct: 74 KPVCESLIIVQYIDEVWKDSAP-LLPSDPYQRAQSRF---WADFVDKKIYDLGRKIWTKK 129 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 ++ ++ L + E L + Y GET D+ +P + Sbjct: 130 --------GEEQEAAKKDF---IDSLKLMEGELGDKPYFGGETIGYVDIALVPFYSWFYA 178 Query: 183 TPTKKLF---TERPRVNEWVAEITKRPASEKV 211 T F E P++ + ++ K Sbjct: 179 YETIGNFNIEAECPKMIAYCKRCLQKETVSKA 210 >6EP7-A nrPDB Length = 220 Score = 92.9 bits (229), Expect = 9e-20, Method: Composition-based stats. Identities = 41/213 (19%), Positives = 74/213 (34%), Gaps = 24/213 (11%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-QVPAFEDGD 62 I + + AS+ R IAL EK + +E +L +K L NP ++P Sbjct: 5 IILLDYWASMYGMRTRIALEEKKVKYEYREEDLS---NKSPLLLQMNPIHKKIPVLIHEG 61 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES QYI + + +L +D +Q + ++ Sbjct: 62 KPICESIIQVQYIDELWPDT-NPILPSDPYQRAQARFW---------------ADYIDKK 105 Query: 123 IFKSIYGLTTDEAVVAE-EEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHI---PAIQ 178 + L ++ E + + +VL ++ L + Y G F L D+ I + Sbjct: 106 TYVPCKALWSESGEKQEAAKIEFIEVLKTLDSELGDKYYFGGNEFGLVDIAFIGFYSWFR 165 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEKV 211 + E P++ W KR + K Sbjct: 166 TYEEVANLSIVLEFPKLMAWAQRCLKRESVAKA 198 >3PR8-A nrPDB Length = 229 Score = 92.5 bits (228), Expect = 1e-19, Method: Composition-based stats. Identities = 48/208 (23%), Positives = 79/208 (37%), Gaps = 17/208 (8%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 +K++G S V +AL EK L FE V G+ L +P G+VP E Sbjct: 2 SLKLYGFSVSNYYNMVKLALLEKGLTFE--EVTFYGGQ--APQALEVSPRGKVPVLETEH 57 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 L E+ I YI G LL D Q + + ++E + P + A Sbjct: 58 GFLSETSVILDYIEQTQG--GKALLPADPFG--QAKVRELLKEIELYIELPARTCYA--- 110 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 +S +G++ + + + A L + + Y+AGE TL DL ++ Sbjct: 111 --ESFFGMSVEPLIKEKARADLLAGFATLKRNGRFAPYVAGEQLTLADLMFCFSVDLANA 168 Query: 183 TPTKKL----FTERPRVNEWVAEITKRP 206 K L + P+ + + + P Sbjct: 169 VGKKVLNIDFLADFPQAKALLQLMGENP 196 >5ECL-B nrPDB Length = 223 Score = 91.3 bits (225), Expect = 2e-19, Method: Composition-based stats. Identities = 37/209 (17%), Positives = 73/209 (34%), Gaps = 22/209 (10%) Query: 6 VFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQ-VPAFEDGDLK 64 + + S+ R +AL EK ++FE + +K L NP + +P Sbjct: 13 LLDYWPSMFGMRARVALREKGVEFEYREEDFS---NKSPLLLQSNPIHKKIPVLVHNGKP 69 Query: 65 LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIF 124 + ES + QY+ + + +D +Q A + + F Sbjct: 70 VCESLNVVQYVDEAWPEK-NPFFPSDPYGRAQARFWADFVDKKFTDAQ-----------F 117 Query: 125 KSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIP---AIQYLL 181 K ++ +E + K+L E+ L + Y G++F D+ I Q Sbjct: 118 KVWGKKGEEQEAGKKEFIEAVKIL---ESELGDKPYFGGDSFGYVDISLITFSSWFQAYE 174 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEK 210 + +E P++ W ++ + K Sbjct: 175 KFGNFSIESESPKLIAWAKRCMEKESVSK 203 >5G5A-A nrPDB Length = 221 Score = 89.8 bits (221), Expect = 7e-19, Method: Composition-based stats. Identities = 42/211 (19%), Positives = 76/211 (36%), Gaps = 22/211 (10%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQ-VPAFEDGD 62 + + S+ R IAL EKN+ F+ +L +K L NP + +P Sbjct: 5 VILLDFWPSMFGMRTRIALEEKNVKFDYREQDLW---NKSPILLEMNPVHKKIPVLIHNG 61 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES +YI + ++ LL +D +Q + + + +++L + Sbjct: 62 NPVCESLIQIEYIDEVWPSKTP-LLPSDPYQRAQAKFWGDFIDKKVY----ASARLIW-- 114 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHI---PAIQY 179 EA E +L E+ L + Y GETF D+ I + Sbjct: 115 ----GAKGEEHEAGKKEFIE----ILKTLESELGDKTYFGGETFGYVDIALIGFYSWFEA 166 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 + + E P++ W +R + K Sbjct: 167 YEKFGSFSIEAECPKLIAWGKRCVERESVAK 197 >5LOL-A nrPDB Length = 215 Score = 89.4 bits (220), Expect = 1e-18, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 67/204 (32%), Gaps = 35/204 (17%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 ++RVL+ L EK L ++ + + D K + FL +P G+VP + + +S I Sbjct: 22 CPFSQRVLLTLEEKKLPYKTHLINVSD---KPQWFLDISPEGKVPVVKLDGKWVADSDVI 78 Query: 72 TQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLT 131 + +Y P +IF + Sbjct: 79 VGLLEEKYPEPSLK--------------------------TPPEFASVGSKIFGAFVTFL 112 Query: 132 TDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYL-LGTPTKKL 188 + E L L+ E LK ++AGE T DL P + +L + K Sbjct: 113 KSKDANDGSEKALVDELEALENHLKTHSGPFVAGEKITAVDLSLAPKLYHLEVALGHYKN 172 Query: 189 F---TERPRVNEWVAEITKRPASE 209 + V + + R + E Sbjct: 173 WSVPESLTSVRNYAKALFSRESFE 196 >3RBT-A nrPDB Length = 246 Score = 89.0 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 35/220 (15%), Positives = 74/220 (33%), Gaps = 35/220 (15%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED-- 60 ++++ + RVL+ L K + +E+ ++ E F ++NP ++P E Sbjct: 26 KLRLYHVDMNPYGHRVLLVLEAKRIKYEVYRLDPLR---LPEWFRAKNPRLKIPVLEIPT 82 Query: 61 --GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKL 118 GD LFES I Y+ +Y + T ++ ++ + + Sbjct: 83 DQGDRFLFESVVICDYLDEKY-TRHTLHSHDPYVKAQDRLLIERFNELIKGSLECFDTNF 141 Query: 119 AFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARL--KEFKYLAGETFTLTDLHHIPA 176 AF ++ + L+++E L + Y G + D P Sbjct: 142 AF-------------------GSEQIIQTLEIFEKELTNRGTNYFGGNRPGMLDYMVWPW 182 Query: 177 IQYLLGTPTKKLF------TERPRVNEWVAEITKRPASEK 210 ++ L + P +W ++ +K Sbjct: 183 VERLYLLRCVNDRKFVEKKSLFPNFADWGDQMQLDDIVKK 222 >5F8B-A nrPDB Length = 244 Score = 87.5 bits (215), Expect = 4e-18, Method: Composition-based stats. Identities = 50/214 (23%), Positives = 79/214 (36%), Gaps = 18/214 (8%) Query: 1 MAGIKVFGHPASIA-TRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE 59 M ++ P T + LD ++ + LS + G+VPAF+ Sbjct: 1 MVFGTLYTFPGDQCRTIAIKAVAKANGLDLDIRET------PRTPDHLSISKLGKVPAFQ 54 Query: 60 DGD-LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKL 118 D KLFE AI YI + + T LL D K +YA + M F+ L Sbjct: 55 GADSFKLFECMAIALYITSQN--EQTTLLGKDKK---EYAEIIKWMSF----FNTEIVIL 105 Query: 119 AFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ 178 +Q+ + + D V + +DV E L++ +L G+ +L DL I Sbjct: 106 MTQQLLPQLGVIPYDRDQVEFFANMTQRSVDVVEEYLQDRTFLVGDQLSLADLFCAGNIS 165 Query: 179 -YLLGTPTKKLFTERPRVNEWVAEITKRPASEKV 211 K + P V+ W + +P V Sbjct: 166 LGFQFFYGKAWRQQNPNVSRWYEMVCHQPIYAAV 199 >4WR5-A nrPDB Length = 244 Score = 86.7 bits (213), Expect = 6e-18, Method: Composition-based stats. Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 19/159 (11%) Query: 52 FGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 F +P DGD+KL +S AI + IA ++ G + ++ + A++ I V Sbjct: 76 FPNLPYXIDGDVKLTQSMAIIRXIADKHNMLGGCPKERAEISMLEGAVLDIRYGV----- 130 Query: 112 DPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDL 171 S++A+ + F E + + +KL ++L ++E RL L G+ T D Sbjct: 131 ----SRIAYSKDF---------ETLKVDFLSKLPEMLKMFEDRLCHKTXLNGDHVTHPDF 177 Query: 172 HHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 A+ +L P++ + I P +K Sbjct: 178 MLYDALDVVLXM-DPMCLDAFPKLVCFKKRIEAIPQIDK 215 >5D73-A nrPDB Length = 208 Score = 86.7 bits (213), Expect = 6e-18, Method: Composition-based stats. Identities = 34/208 (16%), Positives = 73/208 (35%), Gaps = 19/208 (9%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 K+ P + + L ++ + F + D K F FGQ+P DGD Sbjct: 2 SYKLTYFPIRGLAEPIRLVLVDQGIKFTDDRINASDWPSMKSHFH----FGQLPCLYDGD 57 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 ++ +S AI +++A ++ G N L+T ++ + + + + + Sbjct: 58 HQIVQSGAILRHLARKHNLNGGNELETTHIDMFCEGVRDLHTK--------------YTK 103 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 + Y D + +LAK + R ++ GE + D + + Sbjct: 104 MIYQAYDTEKDSYIKDILPVELAKFEKLLATRDDGKNFILGEKISYVDFVLFEELD-IHQ 162 Query: 183 TPTKKLFTERPRVNEWVAEITKRPASEK 210 + P + + + RP ++ Sbjct: 163 ILDPHCLDKFPLLKAYHQRMEDRPGLKE 190 >3R2Q-A nrPDB Length = 202 Score = 86.3 bits (212), Expect = 8e-18, Method: Composition-based stats. Identities = 42/211 (19%), Positives = 83/211 (39%), Gaps = 15/211 (7%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +K+ G S R++ I L EK + FE ++ + ++ F NP G+VP + Sbjct: 1 MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQF---NPLGKVPVLVTEEG 57 Query: 64 K-LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + F+S I +YI N +L D + ++E + + L + Sbjct: 58 ECWFDSPIIAEYIE--LMNVAPAMLPRDPLESLRVR------KIEALADGIMDAGLVSVR 109 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL-L 181 +++ ++ + K+ + LDV E L + L +T L + A+ YL Sbjct: 110 EQARPAAQQSEDELL-RQREKINRSLDVLEGYLVDGT-LKTDTVNLATIAIACAVGYLNF 167 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 +RP + + V + R + + + Sbjct: 168 RRVAPGWCVDRPHLVKLVENLFSRESFARTE 198 >5N9U-A nrPDB Length = 218 Score = 86.0 bits (211), Expect = 1e-17, Method: Composition-based stats. Identities = 40/207 (19%), Positives = 68/207 (32%), Gaps = 40/207 (19%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 +RVL++L EK + ++ + L D K + FL +P G+VP + D + +S I Sbjct: 20 CPFCQRVLLSLEEKKIPYKSHLINLGD---KPQWFLEISPEGKVPVVKIDDKWVADSDVI 76 Query: 72 TQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLT 131 + + P +IF S Sbjct: 77 VGILEEKNPEPP--------------------------LATPPEFASVGSKIFPSFVKFL 110 Query: 132 TDEAVVAEEEAKLAKVLDVYEARLK-EFKYLAGETFTLTDLHHIPAIQYLL-------GT 183 + E L + L + LK ++AGE T DL P + +L Sbjct: 111 KSKDPNDGTEQALLEELKALDGHLKVHGPFIAGEKITAVDLSLAPKLYHLEVALGHFKNW 170 Query: 184 PTKKLFTERPRVNEWVAEITKRPASEK 210 P T V ++ + R + +K Sbjct: 171 PIPDNLT---HVLNYIKLLFSRESFKK 194 >3BBY-A nrPDB Length = 215 Score = 86.0 bits (211), Expect = 1e-17, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 68/175 (38%), Gaps = 10/175 (5%) Query: 9 HPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFES 68 H S +AL EK L F + ++L GEH + + +VP + D +L ES Sbjct: 14 HFFSPYVLSAWVALQEKGLSFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSES 73 Query: 69 RAITQYIAHRYENQG-TNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSI 127 AI +Y+ R+ + D +N ++ + ++ + + E+ + Sbjct: 74 SAIAEYLEDRFAPPTWERIYPLDLENRARARQIQAWLRSD-------LMPIREERPTDVV 126 Query: 128 YGLTTDEAVVAEEEAKLAKVLDVYEARLK-EFKYLAGETFTLTDLHHIPAIQYLL 181 + + AE +A K+ + E L L GE + + D I L+ Sbjct: 127 FAGAKKAPLTAEGKASAEKLFAMAEHLLVLGQPNLFGE-WCIADTDLALMINRLV 180 >2PVQ-A nrPDB Length = 201 Score = 85.2 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 43/210 (20%), Positives = 76/210 (36%), Gaps = 18/210 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHK-KEPFLSRNPFGQVPAFE-DG 61 +K++ + A+ I L E L +EL V+LK + + + NP G VPA E Sbjct: 1 MKLYYKVGA-ASLAPHIILSEAGLPYELEAVDLKAKKTADGGDYFAVNPRGAVPALEVKP 59 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 + ++ AI QYI + + +I + + D AF Sbjct: 60 GTVITQNAAILQYIGD---HSDVAAFKPAYGSIERARLQEALGFCSDLH-------AAFS 109 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 +F V+A +L ++ + + Y G+ FT D + I + Sbjct: 110 GLFAPNLSEEARAGVIANINRRLGQLEAMLSD---KNAYWLGDDFTQPDAYASVIIGW-- 164 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASEKV 211 G K + P+ + + RP +K Sbjct: 165 GVGQKLDLSAYPKALKLRERVLARPNVQKA 194 >3WD6-A nrPDB Length = 256 Score = 84.4 bits (207), Expect = 3e-17, Method: Composition-based stats. Identities = 44/195 (22%), Positives = 78/195 (40%), Gaps = 23/195 (11%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED- 60 ++V+ +R ++AL+ K +D+E+V+++L D K E +++ F +VPA E Sbjct: 28 GKLRVYNMRYCPYAQRTILALNAKQIDYEVVNIDLID---KPEWLTTKSAFAKVPAIEIA 84 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 D+ ++ES +Y+ Y + LL D + I+ V + Sbjct: 85 EDVTIYESLVTVEYLDEVYPKR--PLLPQDPLKKALDKII-------------VEASAPI 129 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK--YLAGETFTLTDLHHIPAIQ 178 + +F I L + V E A K LD + +LK +L G D P + Sbjct: 130 QSLFIKI--LKFSDTVNEEHVAAYHKALDFIQEQLKNRGTVFLDGSEPGYADYMIWPWFE 187 Query: 179 YLLGTPTKKLFTERP 193 L + P Sbjct: 188 RLRAFAHDERVRLEP 202 >2FHE-A nrPDB Length = 216 Score = 79.8 bits (195), Expect = 8e-16, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 69/198 (34%), Gaps = 26/198 (13%) Query: 16 RRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG----QVPAFEDGDLKLFESRAI 71 + V + L +E E DGE + F + G +P + D KL +S AI Sbjct: 14 QPVRLLLEYLGEKYEEQIYERDDGE---KWFSKKFELGLDLPNLPYYIDDKCKLTQSLAI 70 Query: 72 TQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLT 131 +YIA ++ GT + ++ + A + + + + P Sbjct: 71 LRYIADKHGMIGTTSEERARVSMIEGAAVDLRQGISRISYQPKF---------------- 114 Query: 132 TDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTE 191 E + L + ++ L + YL G + + D A+ + Sbjct: 115 --EQLKEGYLKDLPTTMKMWSDFLGKNPYLRGTSVSHVDFMVYEALDA-IRYLEPHCLDH 171 Query: 192 RPRVNEWVAEITKRPASE 209 P + ++++ I P+ + Sbjct: 172 FPNLQQFMSRIEALPSIK 189 >1GWC-A nrPDB Length = 230 Score = 79.4 bits (194), Expect = 1e-15, Method: Composition-based stats. Identities = 43/218 (19%), Positives = 75/218 (34%), Gaps = 30/218 (13%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQ-VPAFEDGD 62 +K+ G S RV +AL K L +E V +L K E L NP + +P Sbjct: 7 LKLLGAWPSPFVTRVKLALALKGLSYEDVEEDLYK---KSELLLKSNPVHKKIPVLIHNG 63 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + ES I QYI + + G +LL D + ++ Sbjct: 64 APVCESMIILQYIDEVFASTGPSLLPADPYERAIARFWV---------------AYVDDK 108 Query: 123 IFKSIYG--LTTDEAVVAEEEAKLAKVLDVYEARLKEF----KYLAGETFTLTDLHH--- 173 + E +E + + + V E L+E + G+ L D+ Sbjct: 109 LVAPWRQWLRGKTEEEKSEGKKQAFAAVGVLEGALRECSKGGGFFGGDGVGLVDVALGGV 168 Query: 174 IPAIQYLLGTPTKKLFT--ERPRVNEWVAEITKRPASE 209 + ++ K+F + P + WV + A++ Sbjct: 169 LSWMKVTEALSGDKIFDAAKTPLLAAWVERFIELDAAK 206 >2WRT-A nrPDB Length = 218 Score = 77.9 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 59/156 (37%), Gaps = 19/156 (12%) Query: 54 QVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDP 113 +P + D KL +S AI +YIA ++ G+ + ++ + A M + M ++P Sbjct: 54 NLPYYIDDKCKLTQSVAIMRYIADKHGMLGSTPEERARISMIEGAAMDLRMGFVRVCYNP 113 Query: 114 VASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHH 173 E V + +L L ++ L + YL G + + D Sbjct: 114 KF------------------EEVKGDYLKELPTTLKMWSNFLGDRHYLTGSSVSHVDFMV 155 Query: 174 IPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 A+ + + + P++ E+ + I P + Sbjct: 156 YEALDC-IRYLAPQCLEDFPKLKEFKSRIEDLPKIK 190 >4AGS-A nrPDB Length = 471 Score = 77.5 bits (189), Expect = 4e-15, Method: Composition-based stats. Identities = 36/200 (18%), Positives = 66/200 (33%), Gaps = 23/200 (11%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 +K++ RV I EK + ++ V V L+ E + + NP VP E G+ Sbjct: 27 LKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLR--EEMPQWYKQINPRETVPTLEVGNA 84 Query: 64 K---LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +FES I QY+ + L+ + + Q V + Sbjct: 85 DKRFMFESMLIAQYLDNS-GAPAGALMGSSAAQRHQIEFF----------LAQVGDFIGA 133 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY- 179 + + A + +L + Y FT+ D+ +P + Sbjct: 134 AHGLLRDPLSGEKRKAMDDNAAYVDGLLAANQT---TGPYYCDGEFTMADVALVPFLVRL 190 Query: 180 ---LLGTPTKKLFTERPRVN 196 L+ +F + PR+ Sbjct: 191 KPALMYYAGYDVFCKAPRMK 210 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 38/216 (17%), Positives = 67/216 (31%), Gaps = 22/216 (10%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 G ++ + R +A + +V V L + E + NP VPA Sbjct: 251 GGHVLYSNLFCPFVDRARLASELRKFQMHIVEVPLHP---QPEWYKYINPRDTVPALFTP 307 Query: 62 DL-KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 + ES+ I QYI +G+ L+ + E F A Sbjct: 308 SGEAVHESQLIVQYIDC-VATKGSALVPRG----------DAEKEYEVGFFVENAGYFVG 356 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY- 179 + I G +A + +L + L + E + G+ D+ +P + Sbjct: 357 GLMSWIIRGGEDAKAELQWAAGELEQQLA--KHPFGEGPFFGGKRMNAGDVAILPFLVRA 414 Query: 180 ----LLGTPTKKLFTERPRVNEWVAEITKRPASEKV 211 + LF P +N P ++ V Sbjct: 415 KAFMPEFSGGYDLFAHFPLLNGLAEAGMATPEAKSV 450 >1OYJ-A nrPDB Length = 231 Score = 76.7 bits (187), Expect = 7e-15, Method: Composition-based stats. Identities = 42/225 (18%), Positives = 72/225 (32%), Gaps = 31/225 (13%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-QVPAFEDGD 62 + + S +R IA+ EK L+FE +L +K + L NP ++P Sbjct: 7 LVLLDFWVSPFGQRCRIAMAEKGLEFEYREEDLG---NKSDLLLRSNPVHRKIPVLLHAG 63 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSK---NISQYAIMAIGMQVEDHQFDPVASKLA 119 + ES I QY+ + L +S A D + S+L Sbjct: 64 RPVSESLVILQYLDDAFPGTPHLLPPANSGDADAAYARATARFWADYVDRKLYDCGSRLW 123 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLT---DLHHIP- 175 + A ++A++L EA L + ++ G D+ +P Sbjct: 124 RLKG-----------EPQAAAGREMAEILRTLEAELGDREFFGGGGGGRLGFVDVALVPF 172 Query: 176 --AIQYLLGTPTKKLFTERPRVNEWVAE-------ITKRPASEKV 211 + PR+ W + P+ EKV Sbjct: 173 TAWFYSYERCGGFSVEEVAPRLAAWARRCGRIDSVVKHLPSPEKV 217 >5AN1-A nrPDB Length = 219 Score = 76.3 bits (186), Expect = 8e-15, Method: Composition-based stats. Identities = 37/215 (17%), Positives = 72/215 (33%), Gaps = 28/215 (13%) Query: 3 GIKVFGHPASIA-TRRVLIALHEKNLDFELVHVELKDG-EHKKEPFLSRN-----PFGQV 55 + V G+ + A + + + L +FE + + D ++ K +L+ F + Sbjct: 1 MLPVLGYWKTRALCQPIRLMLGYTGTEFEEKNYPVGDAPDYDKSEWLAVKFKLGLAFPNL 60 Query: 56 PAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVA 115 P + DGD+K+ +S+AI +Y+A ++ GT + ++ + + + Sbjct: 61 PYYIDGDVKITQSKAIMRYLARKHGLCGTTPEELVRTDMIECQLTDM------------- 107 Query: 116 SKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIP 175 E F Y A L L Y L + AG+ T D Sbjct: 108 ----HEAFFTVTY---EHYEQKDAYTASLPAKLRQYSDFLGSRPWFAGDKLTYIDFLAYE 160 Query: 176 AIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 L + + + A +K Sbjct: 161 IFDQHLSL-DRTCLDGFKNLQAFQKRFEDLEAIKK 194 >2VCT-A nrPDB Length = 222 Score = 76.3 bits (186), Expect = 8e-15, Method: Composition-based stats. Identities = 42/213 (19%), Positives = 77/213 (36%), Gaps = 29/213 (13%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHV----ELKDGEHKKEPFLSRNPFGQVPAFED 60 K+ + L ++FE + +L + + +L F QVP E Sbjct: 6 KLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKL--RNDGYLM---FQQVPMVEI 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +KL ++RAI YIA +Y G K+I + A++ + ++ + L Sbjct: 61 DGMKLVQTRAILNYIASKYNLYG--------KDIKEKALIDMYIEG--------IADLGE 104 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVL-DVYEARLKEF--KYLAGETFTLTDLHHIPAI 177 + +A +A + K +E LK YL G + D+H + + Sbjct: 105 MILLLPFTQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELL 164 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 Y+ L + P + I+ P +K Sbjct: 165 YYVEEL-DSSLISSFPLLKALKTRISNLPTVKK 196 >1VF1-A nrPDB Length = 229 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 41/212 (19%), Positives = 76/212 (35%), Gaps = 29/212 (13%) Query: 6 VFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-----QVPAFED 60 ++ + L ++FE V +E +E + G QVP E Sbjct: 7 LYYFNGRGKMESIRWLLAAAGVEFEEVFLE------TREQYEKLLQSGILMFQQVPMVEI 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +KL ++RAI YIA +Y G +L + A++ + + D + F Sbjct: 61 DGMKLVQTRAILNYIAGKYNLYGKDL--------KERALIDMYVGGTDDL-------MGF 105 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQ 178 F + + E ++ YE LK+ +L G + D+H + AI Sbjct: 106 LLSFPFLSAEDKVKQCAFVVEKATSRYFPAYEKVLKDHGQDFLVGNRLSWADIHLLEAIL 165 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 ++ + P + + I+ P +K Sbjct: 166 -MVEEKKSDALSGFPLLQAFKKRISSIPTIKK 196 >3I6A-A nrPDB Length = 222 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 43/213 (20%), Positives = 77/213 (36%), Gaps = 29/213 (13%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHV----ELKDGEHKKEPFLSRNPFGQVPAFED 60 K+ L ++FE + +L + + +L F QVP E Sbjct: 6 KLHYFNGRGRMESTRWLLAAAGVEFEEKFIKSAEDLDKL--RNDGYLM---FQQVPMVEI 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +KL ++RAI YIA +Y G K+I + A++ + ++ + L Sbjct: 61 DGMKLVQTRAILNYIASKYNLYG--------KDIKERALIDMYIEG--------IADLGE 104 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVL-DVYEARLKEF--KYLAGETFTLTDLHHIPAI 177 I +A +A + K+ +E LK YL G + D+H + + Sbjct: 105 MIIMLPFCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELL 164 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 Y+ L + P + I+ P +K Sbjct: 165 YYVEEL-DSSLISSFPLLKALKTRISNLPTVKK 196 >1PL2-A nrPDB Length = 222 Score = 75.9 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 43/213 (20%), Positives = 78/213 (36%), Gaps = 29/213 (13%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHV----ELKDGEHKKEPFLSRNPFGQVPAFED 60 K+ A L ++FE + +L + + +L F QVP E Sbjct: 6 KLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKL--RNDGYLM---FQQVPMVEI 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +KL + RAI YIA +Y G K+I + A++ + ++ + L Sbjct: 61 DGMKLVQERAILNYIASKYNLYG--------KDIKERALIDMYIEG--------IADLGE 104 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVL-DVYEARLKEF--KYLAGETFTLTDLHHIPAI 177 + + +A +A + K+ +E LK YL G + D+H + + Sbjct: 105 MILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELL 164 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 Y+ L + P + I+ P +K Sbjct: 165 YYVEEL-DSSLISSFPLLKALKTRISNLPTVKK 196 >2GLR-A nrPDB Length = 209 Score = 75.6 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 38/214 (17%), Positives = 76/214 (35%), Gaps = 30/214 (14%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDF--ELVHVELKDGEHKKEPFLSRNPFGQVPAFE 59 + P + + L ++ + E+V ++ K L +GQ+P FE Sbjct: 1 PPYTIVYFPVRGRCEAMRMLLADQGQSWKEEVVTIDTWMQGLLKPTCL----YGQLPKFE 56 Query: 60 DGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 DGDL L++S AI +++ G +L + + VED + V Sbjct: 57 DGDLTLYQSNAILRHL-------GRSLGLYGKNQREAAQMDMVNDGVEDLRGKYVTLIY- 108 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK----YLAGETFTLTDLHHIP 175 T E + L L +E L + + ++ G+ + D + + Sbjct: 109 -----------TNYENGKNDYVKALPGHLKPFETLLSQNQGGKAFIVGDQISFADYNLLD 157 Query: 176 AIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 + + P ++ +VA ++ RP + Sbjct: 158 LLL-IHQVLAPGCLDNFPLLSAYVARLSARPKIK 190 >1HNA-A nrPDB Length = 217 Score = 75.2 bits (183), Expect = 2e-14, Method: Composition-based stats. Identities = 32/207 (15%), Positives = 67/207 (32%), Gaps = 25/207 (12%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVP 56 + + + + L + +E + + E F F +P Sbjct: 1 PMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 60 Query: 57 AFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVAS 116 DG K+ +S AI +YIA ++ G + + ++I + M MQ+ +DP Sbjct: 61 YLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF- 119 Query: 117 KLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPA 176 E + E L ++L +Y L + + G+ T D Sbjct: 120 -----------------EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDV 162 Query: 177 IQYLLGTPTKKLFTERPRVNEWVAEIT 203 ++ P + ++++ Sbjct: 163 LER-NQVFEPSCLDAFPNLKDFISRFE 188 >1FHE-A nrPDB Length = 217 Score = 74.8 bits (182), Expect = 3e-14, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 57/156 (36%), Gaps = 19/156 (12%) Query: 54 QVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDP 113 +P + D KL +S AI +YIA ++ GT + ++ + A M + + ++P Sbjct: 53 NLPYYIDDKCKLTQSVAIMRYIADKHGMLGTTPEERARISMIEGAAMDLRIGFGRVCYNP 112 Query: 114 VASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHH 173 V E +L K L ++ L + YL G + + D Sbjct: 113 KFE------------------EVKEEYVKELPKTLKMWSDFLGDRHYLTGSSVSHVDFML 154 Query: 174 IPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 + + E P++ E+ + I P + Sbjct: 155 YETLDS-IRYLAPHCLDEFPKLKEFKSRIEALPKIK 189 >2DC5-A nrPDB Length = 231 Score = 74.4 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 31/207 (14%), Positives = 67/207 (32%), Gaps = 25/207 (12%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVP 56 + + + + L + +E + + E F F +P Sbjct: 9 PMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLP 68 Query: 57 AFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVAS 116 DG K+ +S AI +Y+ ++ G + +I + +M M V + Sbjct: 69 YLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRM---------VLA 119 Query: 117 KLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPA 176 +L + F E + +L ++ +Y L + + AG+ T D Sbjct: 120 RLCYNADF---------EKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDV 170 Query: 177 IQYLLGTPTKKLFTERPRVNEWVAEIT 203 ++ K P + +++A Sbjct: 171 LER-NQVFEAKCLDAFPNLKDFIARFE 196 >1XWK-A nrPDB Length = 218 Score = 74.0 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 33/195 (16%), Positives = 63/195 (32%), Gaps = 25/195 (12%) Query: 15 TRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFES 68 + + L + +E + + E F F +P DG K+ +S Sbjct: 14 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 73 Query: 69 RAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIY 128 AI YIA ++ G + +I + M MQ+ ++P Sbjct: 74 NAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF------------- 120 Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL 188 E + + +L + L +Y L + + AG T D + L K Sbjct: 121 -----EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD-LHRIFEPKC 174 Query: 189 FTERPRVNEWVAEIT 203 P + ++++ Sbjct: 175 LDAFPNLKDFISRFE 189 >1F3B-A nrPDB Length = 222 Score = 73.2 bits (178), Expect = 8e-14, Method: Composition-based stats. Identities = 42/203 (20%), Positives = 72/203 (35%), Gaps = 35/203 (17%) Query: 18 VLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-----QVPAFEDGDLKLFESRAIT 72 + L ++FE + E G QVP E +KL ++RAI Sbjct: 18 IRWLLAAAGVEFEEKFI------QSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAIL 71 Query: 73 QYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTT 132 YIA +Y+ G K++ + A++ + + L ++ + Sbjct: 72 NYIATKYDLYG--------KDMKERALIDMYSE----------GILDLTEMIGQLVLCPP 113 Query: 133 DEAVVAEEEAKLAKV---LDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYLLGTPTKK 187 D+ AK L +E LK YL G T D+H + + Y+ Sbjct: 114 DQREAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDIHLLEVLLYVEEF-DAS 172 Query: 188 LFTERPRVNEWVAEITKRPASEK 210 L T P + + + I+ P +K Sbjct: 173 LLTPFPLLKAFKSRISSLPNVKK 195 >18GS-A nrPDB Length = 210 Score = 72.9 bits (177), Expect = 9e-14, Method: Composition-based stats. Identities = 39/215 (18%), Positives = 75/215 (34%), Gaps = 30/215 (13%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDF--ELVHVELKDGEHKKEPFLSRNPFGQVPAF 58 M V P + + L ++ + E+V VE K L +GQ+P F Sbjct: 1 MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCL----YGQLPKF 56 Query: 59 EDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKL 118 +DGDL L++S I +++ G L + + VED + ++ Sbjct: 57 QDGDLTLYQSNTILRHL-------GRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIY 109 Query: 119 AFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF----KYLAGETFTLTDLHHI 174 T EA + L L +E L + ++ G+ + D + + Sbjct: 110 ------------TNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLL 157 Query: 175 PAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 + + P ++ +V ++ RP + Sbjct: 158 DLLL-IHEVLAPGCLDAFPLLSAYVGRLSARPKLK 191 >2VCV-A nrPDB Length = 222 Score = 72.9 bits (177), Expect = 9e-14, Method: Composition-based stats. Identities = 39/213 (18%), Positives = 74/213 (34%), Gaps = 29/213 (13%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHV----ELKDGEHKKEPFLSRNPFGQVPAFED 60 K+ + L ++FE + +L + F QVP E Sbjct: 6 KLHYFNGRGRMEPIRWLLAAAGVEFEEKFIGSAEDLGKLRNDGSLM-----FQQVPMVEI 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +KL ++RAI YIA +Y G K+I + A++ + + + L Sbjct: 61 DGMKLVQTRAILNYIASKYNLYG--------KDIKERALIDMYTEG--------MADLNE 104 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLA-KVLDVYEARLKEF--KYLAGETFTLTDLHHIPAI 177 + + +A +A + K + +E L+ YL G + D+ + + Sbjct: 105 MILLLPLCRPEEKDAKIALIKEKTKSRYFPAFEKVLQSHGQDYLVGNKLSRADISLVELL 164 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 Y+ L + P + I+ P +K Sbjct: 165 YYVEEL-DSSLISNFPLLKALKTRISNLPTVKK 196 >1B4P-A nrPDB Length = 217 Score = 72.5 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 32/195 (16%), Positives = 61/195 (31%), Gaps = 25/195 (12%) Query: 15 TRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFES 68 T + + L + +E + + E F F +P DG K+ +S Sbjct: 13 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQS 72 Query: 69 RAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIY 128 AI +Y+A ++ G + ++ + M +Q+ + P Sbjct: 73 NAIMRYLARKHHLCGETEEERIRVDVLENQAMDTRLQLAMVCYSPDF------------- 119 Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL 188 E E L + + +Y L + + AG T D + K Sbjct: 120 -----ERKKPEYLEGLPEKMKLYSEFLGKQPWFAGNKITYVDFLVYDVLDQ-HRIFEPKC 173 Query: 189 FTERPRVNEWVAEIT 203 P + ++VA Sbjct: 174 LDAFPNLKDFVARFE 188 >5FWG-A nrPDB Length = 217 Score = 72.5 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 32/195 (16%), Positives = 64/195 (32%), Gaps = 25/195 (12%) Query: 15 TRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFES 68 T + + L + +E + + E F F +P DG K+ +S Sbjct: 13 THPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQS 72 Query: 69 RAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIY 128 AI +Y+A ++ G + +I + +M MQ+ ++P Sbjct: 73 NAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDF------------- 119 Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL 188 E E + + + +Y L + + AG+ T D + K Sbjct: 120 -----EKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQ-YHIFEPKC 173 Query: 189 FTERPRVNEWVAEIT 203 P + +++A Sbjct: 174 LDAFPNLKDFLARFE 188 >4GTU-A nrPDB Length = 217 Score = 71.7 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 29/195 (14%), Positives = 60/195 (30%), Gaps = 25/195 (12%) Query: 15 TRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFES 68 + + L + +E + + E F F +P DG K+ +S Sbjct: 13 AHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQS 72 Query: 69 RAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIY 128 AI YIA ++ G + +I + M + Q+ + P Sbjct: 73 NAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF------------- 119 Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL 188 E + E +L ++ + L + + G+ T D + L Sbjct: 120 -----EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLD-LHRIFEPNC 173 Query: 189 FTERPRVNEWVAEIT 203 P + ++++ Sbjct: 174 LDAFPNLKDFISRFE 188 >1TU7-A nrPDB Length = 208 Score = 71.3 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 73/208 (35%), Gaps = 19/208 (9%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 K+ + + L ++++ F + D K F FGQ+P DGD Sbjct: 2 SYKLTYFSIRGLAEPIRLFLVDQDIKFIDDRIAKDDFSSIKSQFQ----FGQLPCLYDGD 57 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 ++ +S AI +++A +Y G N ++T I M E + V + + Sbjct: 58 QQIVQSGAILRHLARKYNLNGENEMETT----------YIDMFCEGVRDLHVK----YTR 103 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLG 182 + Y D + + +LAK + R + G+ + D + + Sbjct: 104 MIYMAYETEKDPYIKSILPGELAKFEKLLATRGNGRNLILGDKISYADYALFEELD-VHQ 162 Query: 183 TPTKKLFTERPRVNEWVAEITKRPASEK 210 + P + + + RP ++ Sbjct: 163 ILDPHCLDKFPLLKVFHQRMKDRPKLKE 190 >4Q5F-A nrPDB Length = 218 Score = 71.3 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 18/212 (8%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M K+ + H+ + FE ++ +D K + PFGQ+P E Sbjct: 13 MPQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWPALKP----KTPFGQLPLLEV 68 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 L +S AI +Y+ ++ G ++ +I F Sbjct: 69 DGEVLAQSAAIYRYLGRQFGLAGKTPME----EAQVDSIFDQFKDFMAELRPCFRVLAGF 124 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKE--FKYLAGETFTLTDLHHIPAIQ 178 E+ ++ + K L + E L + +Y+ G++ T DL ++ Sbjct: 125 EEG-------DKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLA 177 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 + ++ +++ + + P +K Sbjct: 178 SWESL-IPDFLSGHLQLKKYIEHVRELPNIKK 208 >1B48-A nrPDB Length = 221 Score = 71.3 bits (173), Expect = 3e-13, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 76/211 (36%), Gaps = 25/211 (11%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHK--KEPFLSRNPFGQVPAFEDGD 62 K++ + L ++FE +E ++ K K+ L FGQVP E Sbjct: 5 KLYYFNGRGRMESIRWLLAAAGVEFEEEFLETREQYEKMQKDGHLL---FGQVPLVEIDG 61 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 + L ++RAI Y+A +Y G +L + ++ + M + Sbjct: 62 MMLTQTRAILSYLAAKYNLYGKDLKERVRIDMYADGTQDLMMMIA--------------- 106 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVL-DVYEARLKEF--KYLAGETFTLTDLHHIPAIQY 179 E ++ V+E LK+ +L G + D+ + AI Sbjct: 107 -VAPFKTPKEKEESYDLILSRAKTRYFPVFEKILKDHGEAFLVGNQLSWADIQLLEAIL- 164 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 ++ + + ++ P + + I+ P +K Sbjct: 165 MVEELSAPVLSDFPLLQAFKTRISNIPTIKK 195 >5LCZ-A nrPDB Length = 222 Score = 70.9 bits (172), Expect = 4e-13, Method: Composition-based stats. Identities = 43/212 (20%), Positives = 80/212 (37%), Gaps = 27/212 (12%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHV----ELKDGEHKKEPFLSRNPFGQVPAFED 60 K+ A L ++FE + +L + + +L F QVP E Sbjct: 6 KLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKL--RNDGYLM---FQQVPMVEI 60 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +KL ++RAI YIA +Y G K++ + A++ + + + + Sbjct: 61 DGMKLVQTRAILNYIASKYNLYG--------KDMKERALIDMYSEGILDLTEMII----- 107 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIPAIQ 178 Q+ + +A++ K + L +E LK YL G T D+ H+ + Sbjct: 108 -QLVICPPDQREAKTALAKDRTK-NRYLPAFEKVLKSHGQDYLVGNRLTRVDI-HLLELL 164 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 + L T P + + + I+ P +K Sbjct: 165 LYVEEFDASLLTSFPLLKAFKSRISSLPNVKK 196 >2GSR-A nrPDB Length = 207 Score = 69.8 bits (169), Expect = 8e-13, Method: Composition-based stats. Identities = 32/212 (15%), Positives = 78/212 (36%), Gaps = 28/212 (13%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 + P + + L +++ ++ V ++ K L F Q+P F+DG Sbjct: 1 PPYTITYFPVRGRCEAMRMLLADQDQSWKEEVVTMETWPPLKPSCL----FRQLPKFQDG 56 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 DL L++S AI +++ + G + + ++ + + + + Sbjct: 57 DLTLYQSNAILRHLGRSFGLYGKDQKEAALVDMVNDGVEDLRCKYATLIY---------- 106 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK----YLAGETFTLTDLHHIPAI 177 T EA + +L + L +E L + + ++ G + D + + + Sbjct: 107 ---------TNYEAGKEKYVKELPEHLKPFETLLSQNQGGQAFVVGSQISFADYNLLDLL 157 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 + + P ++ +VA ++ RP + Sbjct: 158 R-IHQVLNPSCLDAFPLLSAYVARLSARPKIK 188 >4PQI-A nrPDB Length = 241 Score = 69.4 bits (168), Expect = 1e-12, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 80/213 (37%), Gaps = 26/213 (12%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPF-LSRNPFGQVPAFEDGDL 63 K++ +RV I + K L E+ V L +++ + P +VP+ E Sbjct: 34 KLYTCYTCPFAQRVWITRNFKGLQDEIKLVPLIL-QNRPAWYPEKVYPPNKVPSLEHNGK 92 Query: 64 KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQI 123 ES + +Y+ + +G +LL D E + + + Sbjct: 93 ITGESLDLIKYLESNF--EGPSLLPKDPAKKE--------FAEELFSYTDKFNGTVY--- 139 Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ----Y 179 + G EA A + L L + + + G+ F+L D+ +IP ++ + Sbjct: 140 -TAFKGDLAKEAGPAFDH--LENALH----KFDDGPFFLGKEFSLVDIAYIPFVERLNIF 192 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 LL + R ++ W+ E+ K A ++ + Sbjct: 193 LLEVFKYDITAGRQKLAAWIEEVNKIEAYKQTK 225 >3KXO-A nrPDB Length = 202 Score = 68.2 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 62/208 (29%), Gaps = 21/208 (10%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M K+ + ++ +E +E D S PFG++P E Sbjct: 4 MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADW----PEIKSTLPFGKIPILEV 59 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 L L +S AI +Y+ + G ++ + + + + Sbjct: 60 DGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAE----KKQDVK 115 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 EQ+F + ++ + L ++L G + T D + Sbjct: 116 EQMFNELLTYNAPH------------LMQDLDTYLGGREWLIGNSVTWADFY-WEICSTT 162 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPAS 208 L L PR+ ++ PA Sbjct: 163 LLVFKPDLLDNHPRLVTLRKKVQAIPAV 190 >1GSQ-A nrPDB Length = 202 Score = 67.5 bits (163), Expect = 4e-12, Method: Composition-based stats. Identities = 35/210 (16%), Positives = 68/210 (32%), Gaps = 27/210 (12%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 + P L +F VE+ D + K + +P + Sbjct: 1 PKYTLHYFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLK----ATMYSNAMPVLDID 56 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 K+ +S I +++A + G ++ +Y + I ++D F Sbjct: 57 GTKMSQSMCIARHLAREFGLDG-------KTSLEKYRVDEITETLQD----------IFN 99 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLD-VYEARL----KEFKYLAGETFTLTDLHHIPA 176 + K + + V + K K L E L + G + TL DLH A Sbjct: 100 DVVKIKFAPEAAKEAVQQNYEKSCKRLAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVA 159 Query: 177 IQYLLGTPTKKLFTERPRVNEWVAEITKRP 206 ++ L +L + P++ + + P Sbjct: 160 LEVPLKHT-PELLKDCPKIVALRKRVAECP 188 >1EV4-A nrPDB Length = 221 Score = 67.1 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 40/203 (19%), Positives = 71/203 (34%), Gaps = 35/203 (17%) Query: 18 VLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFG-----QVPAFEDGDLKLFESRAIT 72 + L ++F+ + E G QVP E +KL ++RAI Sbjct: 18 IRFLLAAAGVEFDEKFI------QSPEDLEKLKKDGNLMFDQVPMVEIDGMKLAQTRAIL 71 Query: 73 QYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTT 132 YIA +Y+ G K++ + A++ + + L ++ + Sbjct: 72 NYIATKYDLYG--------KDMKERALIDMYSE----------GILDLTEMIMQLVICPP 113 Query: 133 DEAVVAEEEAKLAKV---LDVYEARLKEF--KYLAGETFTLTDLHHIPAIQYLLGTPTKK 187 D+ AK L +E LK YL G T D+ H+ + + Sbjct: 114 DQKEAKTALAKDRTKNRYLPAFEKVLKSHGQDYLVGNKLTRVDI-HLLELLLYVEEFDAS 172 Query: 188 LFTERPRVNEWVAEITKRPASEK 210 L T P + + + I+ P +K Sbjct: 173 LLTSFPLLKAFKSRISSLPNVKK 195 >1ZL9-A nrPDB Length = 207 Score = 66.7 bits (161), Expect = 7e-12, Method: Composition-based stats. Identities = 38/212 (17%), Positives = 64/212 (30%), Gaps = 17/212 (8%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M K+ A +E V + KE + PFGQ+P E Sbjct: 1 MVSYKLTYFNGRGAGEVSRQIFAYAGQQYEDNRVTQEQWPALKETCAA--PFGQLPFLEV 58 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 KL +S AI +++A ++ G + N + + + + Sbjct: 59 DGKKLAQSHAIARFLAREFKLNGKTAWEEAQVNSLADQYKDYSSEARPYFYAVMGFGPGD 118 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLK--EFKYLAGETFTLTDLHHIPAIQ 178 + K L E K LK +L G++ T DL Sbjct: 119 VETLKKDIFLPAFE-----------KFYGFLVNFLKASGSGFLVGDSLTWIDLAIAQHSA 167 Query: 179 YLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 L+ F++ P + +I P +K Sbjct: 168 DLIA--KGGDFSKFPELKAHAEKIQAIPQIKK 197 >4Q5Q-A nrPDB Length = 219 Score = 65.9 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 29/200 (14%), Positives = 71/200 (35%), Gaps = 25/200 (12%) Query: 13 IATRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLF 66 + + + L +DF + E E F F +P + DGD+K+ Sbjct: 13 GYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYYIDGDMKMT 72 Query: 67 ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKS 126 ++ AI +Y+ +Y+ G+N + ++++ + + + Sbjct: 73 QTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAA-----------------MIRV 115 Query: 127 IYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTK 186 Y D+ + + L L + + E ++AG + D + + + + Sbjct: 116 CYDANCDK-LKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCH-VKVMVP 173 Query: 187 KLFTERPRVNEWVAEITKRP 206 ++F + + +V + P Sbjct: 174 EVFGQFENLKRYVERMESLP 193 >1GSU-A nrPDB Length = 219 Score = 65.5 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 26/171 (15%), Positives = 51/171 (29%), Gaps = 26/171 (15%) Query: 15 TRRVLIALHEKNLDFELVHVELKDGEHKKE-------PFLSRNPFGQVPAFEDGDLKLFE 67 + + L ++ + L + F +P DGD+KL + Sbjct: 13 AHAIRLLLEYTETPYQERRYKAGPAPDFDPSDWTNEKEKLGLD-FPNLPYLIDGDVKLTQ 71 Query: 68 SRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSI 127 S AI +YIA ++ G ++ ++ + +M + M + P Sbjct: 72 SNAILRYIARKHNMCGETEVEKQRVDVLENHLMDLRMAFARLCYSPDF------------ 119 Query: 128 YGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQ 178 E + +L L L + G+ T D + Sbjct: 120 ------EKLKPAYLEQLPGKLRQLSRFLGSRSWFVGDKLTFVDFLAYDVLD 164 >4Q5R-A nrPDB Length = 204 Score = 65.2 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 34/208 (16%), Positives = 68/208 (32%), Gaps = 17/208 (8%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 K+ P + L DFE + D + K PFG+ P E Sbjct: 3 PSYKLTYCPVKALGEPIRFLLSYGEKDFEDYRFQEGDWPNLKPSM----PFGKTPVLEID 58 Query: 62 DLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFE 121 + +S AI++Y+ ++ G + + ++ I + ++ +D + Sbjct: 59 GKQTHQSVAISRYLGKQFGLSGKDDWENLEIDMIVDTISDFRAAIANYHYDADENS---- 114 Query: 122 QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLL 181 K + + K +V+ YLA T D + + + YL Sbjct: 115 ---KQKKWDPLKKETIPYYTKKFDEVVK------ANGGYLAAGKLTWADFYFVAILDYLN 165 Query: 182 GTPTKKLFTERPRVNEWVAEITKRPASE 209 + L +P + ++ PA + Sbjct: 166 HMAKEDLVANQPNLKALREKVLGLPAIK 193 >3GTU-B nrPDB Length = 224 Score = 64.8 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 31/197 (15%), Positives = 60/197 (30%), Gaps = 25/197 (12%) Query: 15 TRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFES 68 + + L + +E + + F F +P DG K+ +S Sbjct: 17 AHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLDGKNKITQS 76 Query: 69 RAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIY 128 AI +YIA ++ G + +I + +M Q+ + Sbjct: 77 NAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQL------------------IRLC 118 Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL 188 + E + + +L L + L +F + AGE T D + K Sbjct: 119 YSSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQ-NRIFDPKC 177 Query: 189 FTERPRVNEWVAEITKR 205 E P + ++ Sbjct: 178 LDEFPNLKAFMCRFEAL 194 >2AAW-A nrPDB Length = 222 Score = 64.8 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 39/223 (17%), Positives = 73/223 (32%), Gaps = 42/223 (18%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVH--------VELKDGEHKKEPFLSRNPFGQ 54 I ++ A + + +++ VE K+ + +K+ PF Q Sbjct: 15 NIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEKDT-----PFEQ 69 Query: 55 VPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPV 114 VP + GDL L +S+AI +Y++ +Y G ++++ I V+D + Sbjct: 70 VPILQIGDLILAQSQAIVRYLSKKYNICG-------ESELNEFYADMIFCGVQDIHYKFN 122 Query: 115 ASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK--------YLAGETF 166 + L + + L K +E LK+ Y G Sbjct: 123 NTNLFKQNETTFLN-------------EDLPKWSGYFEKLLKKNHTNNNNDKYYFVGNNL 169 Query: 167 TLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASE 209 T DL + + T P + I+ P + Sbjct: 170 TYADLAVF-NLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIK 211 >1YQ1-A nrPDB Length = 208 Score = 64.8 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 32/211 (15%), Positives = 64/211 (30%), Gaps = 14/211 (6%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M K+ + + H + FE V + + P Q+P Sbjct: 1 MPSYKLTYFFFRGLGEPIRLLFHLAGVQFEEVRMN---PDQTWLDIKDSTPMKQLPVLNI 57 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +L +S AI +Y+A ++ G + + + + + + K A Sbjct: 58 DGFELPQSGAILRYLARKFGFAGKTPEEEAWVDAVHDLFKDFLAEFKKFAAERRSGKSAE 117 Query: 121 E-QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQY 179 E + F+S + L L K +L G T DL + + Sbjct: 118 EVEKFRSEFFLPARNTYFNILNGLLEK---------SNSGFLIGSDITFADLVVVDNLLT 168 Query: 180 LLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 L +E ++ ++ P ++ Sbjct: 169 LKNYGLFDE-SEFTKLAALREKVNSYPGIKE 198 >1GUL-A nrPDB Length = 222 Score = 63.6 bits (153), Expect = 6e-11, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 79/215 (36%), Gaps = 33/215 (15%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVE-------LKDGEHKKEPFLSRNPFGQVPA 57 K+ V L ++F+ +E L+DG H F QVP Sbjct: 6 KLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKEQLYKLQDGNHLL--------FQQVPM 57 Query: 58 FEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASK 117 E +KL ++R+I YIA ++ G KN+ + ++ + ++ + Sbjct: 58 VEIDGMKLVQTRSILHYIADKHNLFG--------KNLKERTLIDMYVEGTL----DLLEL 105 Query: 118 LAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHIP 175 L K + VV + + + V+E L+ +L G +L D+ + Sbjct: 106 LIMHPFLKP---DDQQKEVVNMAQKAIIRYFPVFEKILRGHGQSFLVGNQLSLADVILLQ 162 Query: 176 AIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 I L + + P + E+ +++ P ++ Sbjct: 163 TILALEE-KIPNILSAFPFLQEYTVKLSNIPTIKR 196 >6GC9-A nrPDB Length = 327 Score = 62.1 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 41/242 (16%), Positives = 69/242 (28%), Gaps = 52/242 (21%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVE-------------------------- 35 ++ A R LI K L+ E + V Sbjct: 47 GRYHLYVSYACPWATRTLIVRKIKGLE-EFIDVSVVSPRMGAHGWPFANVDAFPGADADP 105 Query: 36 LKDGEHKKEPFLSRNP--FG--QVPAFEDGDLKLF---ESRAITQYIAHRYENQGTNLLQ 88 L EH K+ ++ NP G VP D ES I + + +Q L Sbjct: 106 LFGAEHVKDLYMRVNPDYEGRFTVPILWDKKTSAIVNNESSEIIRMFNTAFNDQ----LP 161 Query: 89 TDSKNISQYA-IMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKV 147 +D I Y + + + + ++ F T + L + Sbjct: 162 SDKAAIDLYPEALRGEIDGINEWVYDTVNNGVYKSGFA------TSQKAYEAAVVPLFES 215 Query: 148 LDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL-------LGTPTKKLFTERPRVNEWVA 200 LD E L YL G+ T D+ I + + P ++ W+ Sbjct: 216 LDRLEKILTGKDYLVGDQLTEADIRLFVTIVRFDPVYVGHFKCNIRTIRDGYPAIDLWMR 275 Query: 201 EI 202 ++ Sbjct: 276 KL 277 >5Y9Z-A nrPDB Length = 199 Score = 61.7 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 31/207 (14%), Positives = 60/207 (28%), Gaps = 21/207 (10%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M K+ + ++ +E +E D K PFG++P E Sbjct: 1 MPNYKLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTL----PFGKIPVLEV 56 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 L L +S AI +Y+ + G L+ + + + + + F Sbjct: 57 EGLTLHQSLAIARYLTKNTDLAGKTELEQCQVDAVVDTLDDFMSLFPWAEENQDLKERTF 116 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL 180 + + +L + L + ++ G T D + Sbjct: 117 NDLLTR----------------QAPHLLKDLDTYLGDKEWFIGNYVTWADFY-WDICSTT 159 Query: 181 LGTPTKKLFTERPRVNEWVAEITKRPA 207 L L PR+ ++ PA Sbjct: 160 LLVLKPDLLGIYPRLVSLRNKVQAIPA 186 >2WDU-A nrPDB Length = 211 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 72/205 (35%), Gaps = 26/205 (12%) Query: 5 KVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE----D 60 K++ + + L + FE + K P G+VP + D Sbjct: 7 KLWYFQFRGRAEPIRLLLTCAGVKFEDYQFTMDQWPTIKPTL----PGGRVPLLDVTGPD 62 Query: 61 GDLKLF-ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA 119 G L+ + ES AI + +A +++ G + Y I I + ED + Sbjct: 63 GKLRRYQESMAIARLLARQFKMMG-------ETDEEYYLIERIIGECEDLYRE------- 108 Query: 120 FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARL--KEFKYLAGETFTLTDLHHIPAI 177 + + +E +L + L K++AG TL DL + Sbjct: 109 -VYTIFRTPQGEKEAKIKEFKENNGPTLLKLVSESLESSGGKHVAGNRITLGDLFLFTTL 167 Query: 178 QYLLGTPTKKLFTERPRVNEWVAEI 202 +++ T L + P+++E+ + Sbjct: 168 THVMETVPGFLEQKFPKLHEFHKSL 192 >1U3I-A nrPDB Length = 211 Score = 61.3 bits (147), Expect = 3e-10, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 74/201 (36%), Gaps = 30/201 (14%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAF---ED 60 IKV + + L +D+E + +D K P G++PA +D Sbjct: 6 IKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTI----PGGRLPAVKVTDD 61 Query: 61 GDLKLF--ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKL 118 + ES AI +Y+A ++ G +TD + S ++ VE Sbjct: 62 HGHVKWMLESLAIARYMAKKHHMMG----ETDEEYYSVEKLIGQAEDVE----------- 106 Query: 119 AFEQIFKSIYGLTTDEAVVAEE--EAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHI 174 + K++ ++ + +E K+ + ++ LK K G+ TL DL I Sbjct: 107 --HEYHKTLMKPQEEKEKITKEILNGKVPVLFNMICESLKGSTGKLAVGDKVTLADLVLI 164 Query: 175 PAIQYLLGTPTKKLFTERPRV 195 I ++ L + P + Sbjct: 165 AVIDHVTDLDKGFLTGKYPEI 185 >3FY7-A nrPDB Length = 250 Score = 60.9 bits (146), Expect = 4e-10, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 65/169 (38%), Gaps = 11/169 (6%) Query: 11 ASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRA 70 + +R+ + L K + F L V+ + + F P Q+P ++ Sbjct: 41 HCPSCQRLFMVLLLKGVPFTLTTVDTRRSPDVLKDFA---PGSQLPILLYDSDAKTDTLQ 97 Query: 71 ITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVAS--KLAFEQIFKSIY 128 I ++ L + S A + + +PV + + ++Q+ +++ Sbjct: 98 IEDFLEETLGPPDFPSLAPRYRE-SNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALA 156 Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAI 177 L D + A E +LA + E+R ++L G+ TL D +P + Sbjct: 157 RL--DSYLRAPLEHELAGEPQLRESR---RRFLDGDRLTLADCSLLPKL 200 >2HNL-A nrPDB Length = 225 Score = 60.5 bits (145), Expect = 5e-10, Method: Composition-based stats. Identities = 37/214 (17%), Positives = 72/214 (33%), Gaps = 27/214 (12%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + + + N+ +E + + ++ K R PFG VP Sbjct: 25 MEKYTLTYFNGRGRAEVIRLLFALANVSYEDNRITRDEWKYLKP----RTPFGHVPMLNV 80 Query: 61 GDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 L ES AI LL T+ ++ + + + + P + Sbjct: 81 SGNVLGESHAI-----ELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHE--- 132 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKV--LDVYEARLKEFK--YLAGETFTLTDLHHIPA 176 TT +A + ++ + L YE LKE ++ G ++ DL Sbjct: 133 --------KNTTKKAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADL---TV 181 Query: 177 IQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 L+ + E P++ +V +I + P ++ Sbjct: 182 FNMLMTLDDEVKLEEYPQLASFVNKIGQMPGIKE 215 >3PPU-A nrPDB Length = 352 Score = 59.8 bits (143), Expect = 8e-10, Method: Composition-based stats. Identities = 44/250 (17%), Positives = 77/250 (30%), Gaps = 53/250 (21%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLD----------------FELVHVE---------L 36 ++ A R LI K L+ + +V+ L Sbjct: 76 GRYHLYVSYACPWATRTLIVRKLKGLEDFIGVTVVSPRMGSNGWPFANVDPFPAADSDPL 135 Query: 37 KDGEHKKEPFLSRNPFG----QVPAFED---GDLKLFESRAITQYIAHRYENQGTNLLQT 89 + +H K+ +L P VP D G + ES I + + +LL Sbjct: 136 NNAQHVKDLYLKVKPDYDGRFTVPVLWDKHTGTIVNNESSEIIR----MFNTAFNHLLPE 191 Query: 90 DSKNISQYA--IMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKV 147 D + Y + A +V D +D V + + G + + L + Sbjct: 192 DKAKLDLYPESLRAKIDEVNDWVYDTVNNGVY-------KSGFASTQKAYEAAVIPLFES 244 Query: 148 LDVYEARLKEFKYLAGETFTLTDLHHIPAIQYL-------LGTPTKKLFTERPRVNEWVA 200 LD E L+ YL G T D+ I + + P ++ W+ Sbjct: 245 LDRLEKMLEGQDYLIGGQLTEADIRLFVTIVRFDPVYVTHFKCNLRTIRDGYPNLHRWMR 304 Query: 201 EIT-KRPASE 209 ++ PA + Sbjct: 305 KLYWGNPAFK 314 >4FQU-A nrPDB Length = 313 Score = 59.4 bits (142), Expect = 1e-09, Method: Composition-based stats. Identities = 35/239 (14%), Positives = 71/239 (29%), Gaps = 49/239 (20%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKD------------GEHKKEP---- 45 ++ A RVLI K L+ E++ V + + G+ Sbjct: 43 GRYHLYAGFACPWAHRVLIMRALKGLE-EMISVSMVNAYMGENGWTFLPGDDVVPDSING 101 Query: 46 -------FLSRNPFGQ----VPAFEDGDLKLF---ESRAITQYIAHRYENQGTNLLQTDS 91 + + +P +P D K ES I + + +++ G L D Sbjct: 102 ADYLYQVYTAADPTYTGRVTIPILWDKVEKRILNNESSEIIRILNSAFDDVGA--LPGDY 159 Query: 92 KNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVY 151 + ++ ++ + + + G T + E L LD Sbjct: 160 YPAEFRPEID---RINARVYETLNNGVY-------RSGFATTQEAYEEAFYPLFDTLDWL 209 Query: 152 EARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL------FTERPRVNEWVAEITK 204 E L ++L G+ T D+ P + + P ++ V ++ Sbjct: 210 EEHLTGREWLVGDRLTEADIRLFPTLVRFDAIYHGHFKCNLRRIADYPNLSRLVGKLAS 268 >4K0G-A nrPDB Length = 251 Score = 58.2 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 60/167 (35%), Gaps = 7/167 (4%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 S ++R+ + L K + F + V+ K + E P GQ+P G ++ I Sbjct: 34 SPFSQRLFMVLWLKGVTFNVTTVDTKR---RTETVQKLCPGGQLPFLLYGTEVHTDTNKI 90 Query: 72 TQYIAHRY-ENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGL 130 +++ + L + ++ + + +P + + + K++ L Sbjct: 91 EEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVL 150 Query: 131 TTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAI 177 EE D + + K+L G TL D + +P + Sbjct: 151 DNYLTSPLPEEVDETSAED---EGVSQRKFLDGNELTLADCNLLPKL 194 >2CA8-A nrPDB Length = 211 Score = 57.8 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 40/201 (19%), Positives = 75/201 (37%), Gaps = 30/201 (14%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 IKV + + L +++E + +D K P G++PA + D Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTI----PGGRLPAVKITDN 61 Query: 64 K-----LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKL 118 + ES AI +Y+A ++ G Y + + Q ED + Sbjct: 62 HGHVKWMVESLAIARYMAKKHHMMGG-------TEEEYYNVEKLIGQAEDLE-------- 106 Query: 119 AFEQIFKSIYGLTTDEAVVAEE--EAKLAKVLDVYEARLKEF--KYLAGETFTLTDLHHI 174 + +K++ ++ + +E K+ +LD+ LK K G+ TL DL I Sbjct: 107 --HEYYKTLMKPEEEKQKIIKEILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLI 164 Query: 175 PAIQYLLGTPTKKLFTERPRV 195 I ++ + L + P + Sbjct: 165 AVIDHVTDLDKEFLTGKYPEI 185 >3M1G-A nrPDB Length = 362 Score = 57.1 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 38/233 (16%), Positives = 68/233 (29%), Gaps = 29/233 (12%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEH-KKEPFLSRNPFG-----QV 55 ++ A R +I L+ ++ + L H + +P Q+ Sbjct: 60 GRYRLVAARACPWAHRTVITRRLLGLE-NVISLGLTGPTHDVRSWTFDLDPNHLDPVLQI 118 Query: 56 PAFEDGDLKLF--ESRAIT--QYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQF 111 P +D F R IT + + TN + I + Sbjct: 119 PRLQDAYFNRFPDYPRGITVPALVEESSKKVVTNDYPS--ITIDFNLEWKQFHREGAPNL 176 Query: 112 DPVASKLAFEQIFKSIY----------GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYL 161 P + + K I+ G + E +L LD E RL +YL Sbjct: 177 YPAELREEMAPVMKRIFTEVNNGVYRTGFAGSQEAHNEAYKRLWVALDWLEDRLSTRRYL 236 Query: 162 AGETFTLTDLHHIPAIQYLLGTPTKKL------FTERPRVNEWVAEITKRPAS 208 G+ T D+ P + TE P + ++ ++ + P Sbjct: 237 MGDHITEADIRLYPTLVRFDAVYHGHFKCGRNKITEMPNLWGYLRDLFQTPGF 289 >4LMW-A nrPDB Length = 251 Score = 51.3 bits (121), Expect = 3e-07, Method: Composition-based stats. Identities = 39/229 (17%), Positives = 75/229 (32%), Gaps = 30/229 (13%) Query: 13 IATRRVLIALHEKNLDFELVHVELKDGE----HKKEPFLSRNPFG----QVPAFEDGDLK 64 T + L+ K L + VE D E P + P G +P +D + K Sbjct: 23 PNTWKTRYVLNFKGLKYRTEWVEYPDIEAVCKQIGAPATEKKPDGRDHYTLPVIQDPNTK 82 Query: 65 --LFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLA--- 119 + +S AI +Y+ Y + L ++ V F+ V +++ Sbjct: 83 AVVADSDAIAKYLESTYPDT-PRLFPEGTRAFQHAFYQLARPSVLMPIFNIVVARVWKLL 141 Query: 120 -------FEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK-----YLAGETFT 167 F + + G +E ++ L L ++ L+ L G+ T Sbjct: 142 RPRSQEYFRATREQMLGKKLEEIGSEDDWNALESGLARIKSSLEANGAGKDLLLMGDRVT 201 Query: 168 LTDLHHIPAIQYLLGTPTK--KLFTERPRV--NEWVAEITKRPASEKVQ 212 DL +L + + + + + +W + + A E V Sbjct: 202 FADLQLASLFIWLRVSAGEESEDWKRFLSLHEGKWAKFMQQFAAYEFVD 250 >4G0L-A nrPDB Length = 328 Score = 50.1 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 40/243 (16%), Positives = 73/243 (30%), Gaps = 48/243 (19%) Query: 4 IKVFGHPASIATRRVLIALHEKNL-DFELVHV----ELKDGEHKKEPF------------ 46 ++ A R LI K L F V V L++G + F Sbjct: 55 YHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSFPGATGDTLYQNE 114 Query: 47 ------LSRNPFG----QVPAFED---GDLKLFESRAITQYIAHRYENQGTNLLQTDSKN 93 L +P VP D + ES I + ++ G + + Sbjct: 115 FLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAFDALGAK-----AGD 169 Query: 94 ISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEA 153 A+ ++ +D V + + G T + E AK+ + L E Sbjct: 170 YYPPALQTKIDELNGWIYDTVNNGVY-------KAGFATSQEAYDEAVAKVFESLARLEQ 222 Query: 154 RLKEFKYLAGETFTLTDLHHIPAIQYLLGTP------TKKLFTERPRVNEWVAEITKRPA 207 L + +YL G T D+ + K ++ + ++ +I + P Sbjct: 223 ILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPG 282 Query: 208 SEK 210 + Sbjct: 283 IAE 285 >5Y7I-A nrPDB Length = 261 Score = 49.0 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 27/205 (13%), Positives = 64/205 (31%), Gaps = 15/205 (7%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 +R+ + L K + F + V+++ K P P + I Sbjct: 46 CPFCQRLFMVLWLKGVKFTVTTVDMRK---KPAELKDLAPGTNPPFLLYNGTLKTDFIKI 102 Query: 72 TQYIAHRY-ENQGTNLLQTDSKNISQYA-IMAIGMQVEDHQFDPVASKLAFEQIFKSIYG 129 +++ + +L + ++ A I A + + + + FK + Sbjct: 103 EEFLEQTLAPPRYPHLSPVNKESFDVGADIFAKFSAFIKNSPNNPLQEKNLLREFKRLDD 162 Query: 130 LTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLF 189 + + + + K+L G+ TL D + +P + + K Sbjct: 163 YLNSPLPEEIDHNSVETI------TVSNRKFLDGDRLTLADCNLLPKLHVIRVAAKKYCN 216 Query: 190 TERPR----VNEWVAEITKRPASEK 210 E P V ++ +R ++ Sbjct: 217 FEIPDHFTGVWRYLKNADERDEFKQ 241 >6GZF-A nrPDB Length = 341 Score = 48.6 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 32/218 (14%), Positives = 65/218 (29%), Gaps = 50/218 (22%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVEL------KDGEHKKEP---------- 45 ++ A R L+ K L+ + + V + +DG Sbjct: 54 GRYHLYVSYACPWAHRTLVTRTLKGLE-DAISVSVVDPYRAEDGWQFTPEKEGCTHDHVH 112 Query: 46 --------FLSRNP----FGQVPAF---EDGDLKLFESRAITQYIA---HRYENQGTNLL 87 ++ P VP E+ + ES I + + + +L Sbjct: 113 DVDYLRELYVRAAPDVTCRVTVPVLWDTEEDTIVNNESEEIMRMFDTEFDEFADHTVDLY 172 Query: 88 QTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKV 147 Q+ D+ ++P+ + + G T++ E A+L Sbjct: 173 PEG--------YQEKVDQIIDNIYEPINNGVY-------RAGFATEQEPYDEAVAELFGA 217 Query: 148 LDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPT 185 L ++ L + +YLAG+ T D+ + Sbjct: 218 LAHWDDVLADQRYLAGDRLTEADIAMFTTLVRFDNVYH 255 >4USS-A nrPDB Length = 325 Score = 47.4 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 27/163 (16%), Positives = 55/163 (33%), Gaps = 20/163 (12%) Query: 54 QVPAFEDGDLKLF---ESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQ 110 VP D LK ES I + + + + ++ + + + + Sbjct: 128 TVPVLWDKKLKTIVNNESSEIIRMFNTEFND-----IAENAALDLYPSHLQAQIDETNGW 182 Query: 111 FDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTD 170 + ++ F G +EA + +L + LD E L +Y+ G T + D Sbjct: 183 VYDGINNGVYKCGFARKQG-PYEEAAI-----QLYEALDKCEEILGRQRYICGNTLSEAD 236 Query: 171 LHH------IPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPA 207 + + + KKL + P + + +I + P Sbjct: 237 IKLFVTLIRFDEVYAVHFKCNKKLLRDYPNMFNYTKDIFQIPG 279 >6GCB-A nrPDB Length = 325 Score = 47.4 bits (111), Expect = 5e-06, Method: Composition-based stats. Identities = 36/242 (14%), Positives = 69/242 (28%), Gaps = 52/242 (21%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELK------------------------ 37 ++ + R LI K L+ E+V V + Sbjct: 46 GRYHLYVAYSCPWATRTLIVRKIKGLE-EIVGVTIVSPLFSAHGWPFGDVSPFPGAEADP 104 Query: 38 --DGEHKKEPFLSRNPFG----QVPAFED---GDLKLFESRAITQYIAHRYENQGTNLLQ 88 + ++ ++ +L +P VP D + ES I + + L Sbjct: 105 FYNAQYVRDLYLRADPKYEGRFTVPVLWDKKTETVVNNESSEIIR----IFNTAFNEFLP 160 Query: 89 TDSKNISQYA-IMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKV 147 D I Y + + + + ++ F T + L + Sbjct: 161 ADKAAIHLYPEALKSEIDEINEWVYDTVNNGVYKAGFA------TTQQAYEAAVIPLFES 214 Query: 148 LDVYEARLKEFKYLAGETFTLTDLHHI-------PAIQYLLGTPTKKLFTERPRVNEWVA 200 LD E L YL G+ T D+ PA + + P ++ W+ Sbjct: 215 LDRLEKILTGKDYLVGDQLTEADVRLFVTIIRFDPAYVGHFKCNLRTIRDGYPAIHLWLR 274 Query: 201 EI 202 ++ Sbjct: 275 KL 276 >4PTS-A nrPDB Length = 348 Score = 47.1 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 28/86 (32%), Gaps = 6/86 (6%) Query: 129 GLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKL 188 G + +L LD RL + +YL G+T T D+ + Sbjct: 190 GFAGSQDAYDAAYDRLFTKLDELSERLAQQRYLVGDTITEADVRLFTTLARFDAVYHGHF 249 Query: 189 ------FTERPRVNEWVAEITKRPAS 208 +E P + + ++ + P Sbjct: 250 KCNRSKLSEMPVLWAYARDLFQTPGF 275 >4BVY-B nrPDB Length = 186 Score = 47.1 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 48/158 (30%), Gaps = 30/158 (18%) Query: 54 QVPAFEDGDL-KLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFD 112 Q+P + D L I ++ + + + AI+ ++ Q D Sbjct: 41 QIPVLQTNDGPSLTGLTTIAAHLVKQANKEYLL-----GSTAEEKAIVQQWLEYRVTQVD 95 Query: 113 PVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLH 172 +SK + L + L++ YL G FTL D+ Sbjct: 96 GHSSKNDIHTL------------------------LKDLNSYLEDKVYLTGYNFTLADIL 131 Query: 173 HIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEK 210 + + T + + V+ W + I P + Sbjct: 132 LYYGLHRFIVDLTVQEKEKYLNVSRWFSHIQHYPGIRQ 169 >1M0U-A nrPDB Length = 249 Score = 46.7 bits (109), Expect = 8e-06, Method: Composition-based stats. Identities = 34/221 (15%), Positives = 69/221 (31%), Gaps = 35/221 (15%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGD 62 +F + N ++E V V + K P GQ+P E Sbjct: 49 SYTLFYFNVKALAEPLRYLFAYGNQEYEDVRVTRDEWPALKPTM----PMGQMPVLEVDG 104 Query: 63 LKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQ 122 ++ +S ++ +++A G + +I I +++ ++P Sbjct: 105 KRVHQSISMARFLAKTVGLCGATPWEDLQIDIVVDTINDFRLKIAVVSYEP--------- 155 Query: 123 IFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFK-YLAGETFTLTDLHHIPAIQYLL 181 ++ +V + L+ E +K+ +LA T D++ Y+ Sbjct: 156 -----EDEIKEKKLVTLNAEVIPFYLEKLEQTVKDNDGHLALGKLTWADVYFAGITDYMN 210 Query: 182 GTPTKKLFTERPRV-------------NEWVAEITKRPASE 209 + L P + W I KRP +E Sbjct: 211 YMVKRDLLEPYPALRGVVDAVNALEPIKAW---IEKRPVTE 248 >2D2Z-A nrPDB Length = 261 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 25/167 (14%), Positives = 55/167 (32%), Gaps = 7/167 (4%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 ++R+ + L K + F + V+LK K + P P + I Sbjct: 35 CPFSQRLFMILWLKGVVFSVTTVDLKR---KPADLQNLAPGTHPPFITFNSEVKTDVNKI 91 Query: 72 TQYIAHRY-ENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGL 130 +++ + L ++ + + P A++ + K++ L Sbjct: 92 EEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKL 151 Query: 131 TTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAI 177 +E + D+ + K+L G TL D + +P + Sbjct: 152 DEYLNSPLPDEIDENSMEDI---KFSTRKFLDGNEMTLADCNLLPKL 195 >1G7O-A nrPDB Length = 215 Score = 42.0 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 30/211 (14%), Positives = 69/211 (32%), Gaps = 18/211 (8%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE-DGD 62 +K++ + + + KN+ EL L + + + QVP + D Sbjct: 1 MKLYIYDHCPYCLKARMIFGLKNIPVELHV--LLNDDAETPT--RMVGQKQVPILQKDDS 56 Query: 63 LKLFESRAITQYIAHRYENQ---GTNLLQTDSKNI-----SQYAIMAIGMQVEDHQFDPV 114 + ES I Y+ G + + ++ + +F Sbjct: 57 RYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFSTP 116 Query: 115 ASKLAFEQIFKSIYGLTTDEAVVAEEEAK-LAKVLDVYEARLKEFKYLAGETFTLTDLHH 173 A++ F ++ G D ++ K ++ L + + + + GE + D+ Sbjct: 117 AARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVKPNAVNGE-LSEDDIQL 175 Query: 174 IPAIQYLLGTPTKKLFTERPRVNEWVAEITK 204 P ++ L + RV ++ + K Sbjct: 176 FPLLRNLTLVAGINWPS---RVADYRDNMAK 203 >2PBJ-A nrPDB Length = 290 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 30/272 (11%), Positives = 69/272 (25%), Gaps = 76/272 (27%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFE---- 59 + ++ + +V L L +++V V + + + +VP Sbjct: 15 LTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVLRAE-----IKFSSYRKVPILVAQEG 69 Query: 60 DGDLKLFESRA-----------------ITQY------------------------IAHR 78 + +L +S I Y + + Sbjct: 70 ESSQQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGNKYWLMLNEK 129 Query: 79 YENQGTNLLQTDSKNISQYAIMAIGM--QVEDHQFDPVASKLAFEQIFKSIYGLTTDEAV 136 Q + + ++ + + + + + LA E Sbjct: 130 EAQQVYSGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGA 189 Query: 137 VAEEEAKLAKVL-----------------DVYEA-------RLKEFKYLAGETFTLTDLH 172 VA+ A L D+YEA K+ ++ G+ L DL Sbjct: 190 VAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLA 249 Query: 173 HIPAIQYLLGTPTKKLFTERPRVNEWVAEITK 204 ++ + G + + W + + Sbjct: 250 VYGVLRVMEGLDAFDDLMQHTHIQPWYLRVER 281 >2R5G-A nrPDB Length = 247 Score = 40.9 bits (94), Expect = 4e-04, Method: Composition-based stats. Identities = 25/188 (13%), Positives = 58/188 (30%), Gaps = 15/188 (7%) Query: 12 SIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAI 71 +R+ + L K + F + V++ K E P P + I Sbjct: 30 CPFCQRLFMILWLKGVKFNVTTVDMTR---KPEELKDLAPGTNPPFLVYNKELKTDFIKI 86 Query: 72 TQYIAH-----RYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKS 126 +++ RY + ++ + +A + ++ + + K ++ FK Sbjct: 87 EEFLEQTLAPPRYPHLSPKYKESFDVGCNLFAKFSAYIKNTQKEANKNFEKSLLKE-FKR 145 Query: 127 IYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTK 186 + + + E + +L G+ TL D +P + + K Sbjct: 146 LDDYLNTPLLDEIDPDSAE------EPPVSRRLFLDGDQLTLADCSLLPKLNIIKVAAKK 199 Query: 187 KLFTERPR 194 + P Sbjct: 200 YRDFDIPA 207 >3IC4-A nrPDB Length = 92 Score = 40.5 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 3/65 (4%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKK---EPFLSRNPFGQVPA 57 MA + ++G +R L L + +DFE++ ++ +GE +K E S + VP Sbjct: 11 MAEVLMYGLSTCPHCKRTLEFLKREGVDFEVIWIDKLEGEERKKVIEKVHSISGSYSVPV 70 Query: 58 FEDGD 62 GD Sbjct: 71 VVKGD 75 >4LMV-A nrPDB Length = 252 Score = 39.7 bits (91), Expect = 9e-04, Method: Composition-based stats. Identities = 35/239 (14%), Positives = 71/239 (29%), Gaps = 39/239 (16%) Query: 9 HPASIATRRVLIALHEKNLDFELVHV------ELKDGEHKKEPFLSRNPFG----QVPAF 58 P S T ++ AL+ K + ++ V ++ K + P G VP Sbjct: 18 SPWSPNTWKIRYALNIKGIKYKTEWVEYPDIEDVVKKLGGKPT--GKKPDGRDHYTVPVI 75 Query: 59 EDGDLK--LFESRAITQYIAHRYENQGTNLLQTDS-----------KNISQYAIMAIGMQ 105 D + K + + I +Y+ Y + L + +++ + + Sbjct: 76 YDPNTKTVVEDGIKIAKYLDDAYPDT-PRLFPAGTDAFQAAFDDFVWSVTLAFPLLSLLL 134 Query: 106 VEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVL----DVYEARLKEFKYL 161 ++ P S F + +G +E E +L L E L Sbjct: 135 LDVSNSLPPRSSAYFRATREQQFGKRLEEQGGEERWQQLEAGLGKFKGYLERNGAGNDLL 194 Query: 162 -----AGETFT---LTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 G T++ + L + + G+ K +W + E+ Sbjct: 195 LMGTQGGITYSDVQIASLFVWAKVVWGEGSEKWKRLMGF-HGGKWAQFCAQFAEYERAD 252 >5CAX-A nrPDB Length = 101 Score = 39.3 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 I ++G + ++ L + +DFE V V+L + E K + F P+ Sbjct: 20 GKIVMYGLSTCVWCKKTKKLLTDLGVDFEYVFVDLLEEEEKSNAIKQVSRFN--PSVSFP 77 Query: 62 DLKLFESRAIT 72 L + +AI Sbjct: 78 TTILNDEKAIV 88 >3GRX-A nrPDB Length = 82 Score = 35.1 bits (79), Expect = 0.021, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 24/64 (37%), Gaps = 2/64 (3%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDG 61 A ++++ + R L K + F+ + ++ K+E + R+ VP Sbjct: 1 ANVEIYTKETCPYSHRAKALLSSKGVSFQELPIDGNAA--KREEMIKRSGRTTVPQIFID 58 Query: 62 DLKL 65 + Sbjct: 59 AQHI 62 >2YV9-A nrPDB Length = 291 Score = 33.2 bits (74), Expect = 0.075, Method: Composition-based stats. Identities = 34/183 (18%), Positives = 67/183 (36%), Gaps = 24/183 (13%) Query: 21 ALHEKNL-DFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLF--ESRAI---TQY 74 AL+E + E+ V + E K+ FL P P + + +L ++R I + Sbjct: 49 ALYEIGVARVEVKTVNVNS-EAFKKNFLGAQP----PIMIEEEKELTYTDNREIEGRIFH 103 Query: 75 IAHRYENQGTNLLQTDSKNISQ-YAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTD 133 +A + + K I Y + ++ +K+ F++ K + Sbjct: 104 LAKEFNVPLFEKDPSAEKRIENLYRNFKLFLR----------AKVEFDKGKKEPSRVEDL 153 Query: 134 EAVVAEEEAKLAKVLDVYEARLKEFK--YLAGETFTLTDLHHIPAIQYLLGTPTKKLFTE 191 A + ++ + L + L E K YL G + T D +P + ++ L + Sbjct: 154 PAQIKVHYNRVCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFD 213 Query: 192 RPR 194 P Sbjct: 214 IPH 216 >2MZC-A nrPDB Length = 92 Score = 33.2 bits (74), Expect = 0.077, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 20/69 (28%), Gaps = 2/69 (2%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFED 60 M + ++ P R L K +F ++ + R+ P Sbjct: 5 MVDVIIYTRPGCPYCARAKALLARKGAEFN--EIDASATPELRAEMQERSGRNTFPQIFI 62 Query: 61 GDLKLFESR 69 G + + S Sbjct: 63 GSVHVGGSD 71 >2KLX-A nrPDB Length = 89 Score = 31.3 bits (69), Expect = 0.34, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 22/64 (34%), Gaps = 5/64 (7%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSR-NPFGQVPAFE 59 M I ++ P +R L +K + + ++ ++ + R N P Sbjct: 5 MKEIILYTRPNCPYCKRARDLLDKKGVKY----TDIDASTSLRQEMVQRANGRNTFPQIF 60 Query: 60 DGDL 63 GD Sbjct: 61 IGDY 64 >1H75-A nrPDB Length = 81 Score = 31.3 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%), Gaps = 3/62 (4%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 I ++ + A+ + DFE+++V+ L F Q+P GDL Sbjct: 3 ITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAA---EALRAQGFRQLPVVIAGDL 59 Query: 64 KL 65 Sbjct: 60 SW 61 >1S4D-A nrPDB Length = 280 Score = 30.5 bits (67), Expect = 0.52, Method: Composition-based stats. Identities = 29/147 (19%), Positives = 47/147 (31%), Gaps = 4/147 (2%) Query: 20 IALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRY 79 I L + + V ++ H + G VP + S I Y+A ++ Sbjct: 129 ITAGIGGLAYAGIPVTHREVNHAVTFLTGHDSSGLVPDRINWQGIASGSPVIVMYMAMKH 188 Query: 80 ENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAE 139 T L ++ + + + LA + + GL VV Sbjct: 189 IGAITANLIAGGRSPDEPVAFVCNAATPQQAV--LETTLARAEADVAAAGLEPPAIVVVG 246 Query: 140 EEAKLAKVLDVYEARLKEFKYLAGETF 166 E +L LD A L K LA + F Sbjct: 247 EVVRLRAALDWIGA-LDGRK-LAADPF 271 >2X8H-A nrPDB Length = 598 Score = 30.1 bits (66), Expect = 0.66, Method: Composition-based stats. Identities = 12/74 (16%), Positives = 29/74 (39%), Gaps = 1/74 (1%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVE-LKDGEHKKEPFLSRNPFGQVPAFED 60 A + +F ++V L E + + ++ L +G ++ S + VP Sbjct: 18 AAVILFSKTTCPYCKKVKDVLAEAKIKHATIELDQLSNGSAIQKCLASFSKIETVPQMFV 77 Query: 61 GDLKLFESRAITQY 74 + +S+ + +Y Sbjct: 78 RGKFIGDSQTVLKY 91 >5L0V-A nrPDB Length = 357 Score = 29.7 bits (65), Expect = 0.87, Method: Composition-based stats. Identities = 15/113 (13%), Positives = 38/113 (33%), Gaps = 7/113 (6%) Query: 95 SQYAIMAIGMQVEDHQFDPVASKL------AFEQIFKSIYGLTTDEAVVAEEEAKLAKVL 148 S++ + + ++P +S+ E+ G + + + KL Sbjct: 2 SKWKVFIDQINRSLENYEPCSSQNCSCYHGVIEEDLTPFRGGISRKMMAEVVRRKLGTHY 61 Query: 149 DVYEARL-KEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVA 200 + + RL +E + + + + I L + P+V +W+ Sbjct: 62 QITKNRLYRENDCMFPSRCSGVEHFILEVIGRLPDMEMVINVRDYPQVPKWME 114 >6HQD-A nrPDB Length = 420 Score = 29.7 bits (65), Expect = 0.94, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 19/50 (38%) Query: 163 GETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ 212 GE F D I +L T F +R ++ W IT RP V Sbjct: 150 GEEFNWVDRVSIELTTMMLATLLDFPFDDRRKLTRWSDIITTRPGYGLVD 199 >5LKB-A nrPDB Length = 378 Score = 29.7 bits (65), Expect = 0.97, Method: Composition-based stats. Identities = 17/150 (11%), Positives = 52/150 (34%), Gaps = 11/150 (7%) Query: 63 LKLFESRAITQYIAHRYENQG--TNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAF 120 +++ S A +++ ++ L+T + + + +I V F +++ Sbjct: 178 IRILNSSAFDEFVDDDHKKTDLVPAQLKTQIDDFNSWVYDSINNGVYKTGFAE-KAEVYE 236 Query: 121 EQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEA-RLKEFKYLAGETFTLTDLHHIPAIQY 179 ++ L E +++++ +KL + ++ + G+ T D+ + Sbjct: 237 SEVNNVFEHLDKVEKILSDKYSKLKAKYGEEDRQKILGEFFTVGDQLTEADIRLYTTVIR 296 Query: 180 L-------LGTPTKKLFTERPRVNEWVAEI 202 + P ++ WV + Sbjct: 297 FDPVYVQHFKCNFTSIRAGYPFIHLWVRNL 326 >5MB9-A nrPDB Length = 590 Score = 29.3 bits (64), Expect = 1.2, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 2/31 (6%) Query: 28 DFELVHVELKDG--EHKKEPFLSRNPFGQVP 56 D+E + L +H + FL +NP + P Sbjct: 249 DYEYHGIALDKVLIDHFSKEFLKKNPGAKDP 279 >4HQS-A nrPDB Length = 190 Score = 29.3 bits (64), Expect = 1.3, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 40/108 (37%), Gaps = 12/108 (11%) Query: 4 IKVFGHPASIATRRVLIA---LHEKNLDFELVHV--ELKDGEHKKEPFLSRN-----PFG 53 +K + SI + E D+ ++ V GE + F +N + Sbjct: 79 LKFWASWCSICLASLPDTDEIAKEAGDDYVVLTVVSPGHKGEQSEADF--KNWYKGLDYK 136 Query: 54 QVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMA 101 +P D KL E+ + Y + ++ L++T + + AI+ Sbjct: 137 NLPVLVDPSGKLLETYGVRSYPTQAFIDKEGKLVKTHPGFMEKDAILQ 184 >4FIW-A nrPDB Length = 77 Score = 28.9 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 23/62 (37%), Gaps = 3/62 (4%) Query: 4 IKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDL 63 I V+ PA + AL L+++LV + L E +E L+ Q P Sbjct: 3 ITVYTKPACVQCNATKKALDRAGLEYDLVDISLD--EEAREYVLALGYL-QAPVVVADGS 59 Query: 64 KL 65 Sbjct: 60 HW 61 >3IHQ-A nrPDB Length = 132 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 13/27 (48%) Query: 3 GIKVFGHPASIATRRVLIALHEKNLDF 29 + ++ P+S + R+ L E + F Sbjct: 2 MVTLYTSPSSTSCRKARAWLEEHEIPF 28 >4TR1-A nrPDB Length = 92 Score = 28.9 bits (63), Expect = 1.5, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 26/64 (40%), Gaps = 3/64 (4%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVP-AFE 59 M I ++ +++ + L K +DF V++ E +++ + VP F Sbjct: 1 MKNITIYTKNYCPYSKKAVSLLSSKGVDF--KEVDVTHDSKAFEDVMAKTGWDTVPQVFV 58 Query: 60 DGDL 63 D + Sbjct: 59 DEEF 62 >4EVM-A nrPDB Length = 138 Score = 28.6 bits (62), Expect = 2.4, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 40/108 (37%), Gaps = 12/108 (11%) Query: 4 IKVFGHPASIATRRVLIA---LHEKNLDFELVHV--ELKDGEHKKEPFLSRN-----PFG 53 +K + SI + E D+ ++ V GE + F +N + Sbjct: 27 LKFWASWCSICLASLPDTDEIAKEAGDDYVVLTVVSPGHKGEQSEADF--KNWYKGLDYK 84 Query: 54 QVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMA 101 +P D KL E+ + Y + ++ L++T + + AI+ Sbjct: 85 NLPVLVDPSGKLLETYGVRSYPTQAFIDKEGKLVKTHPGFMEKDAILQ 132 >1JOE-A nrPDB Length = 167 Score = 28.2 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 137 VAEEEAKLAKVLDVYEARLKE--FKYLAGETFTLTDLHHI----PAIQYLLGTPTKKLFT 190 + +E K + E +L G++ + D+ + L+GTP ++ + Sbjct: 42 IPNKEILSPKGIHTLEHLFAGFMRDHLNGDSIEIIDISPMGCRTGFYMSLIGTPNEQKVS 101 Query: 191 ERPRVNEWVAEITKRPASE 209 E W+A + + Sbjct: 102 E-----AWLASMQDVLGVQ 115 >3QMX-A nrPDB Length = 99 Score = 28.2 bits (61), Expect = 2.5, Method: Composition-based stats. Identities = 7/34 (20%), Positives = 15/34 (44%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVE 35 A I+++ R L L K ++F+ ++ Sbjct: 16 AKIEIYTWSTCPFCMRALALLKRKGVEFQEYCID 49 >4WZ9-A nrPDB Length = 957 Score = 28.2 bits (61), Expect = 2.6, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 47/150 (31%), Gaps = 4/150 (2%) Query: 56 PAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVA 115 P +++ LK + +IT ++++ + TD + + + + V Sbjct: 191 PCYDEPGLKATFTVSITHSLSYKAISNMPQKTTTDIETDMRTTFFEKTPAMSTYLLAFVV 250 Query: 116 SKLAFE-QIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLK--EFKYLAG-ETFTLTDL 171 S + +Y K+L V + L Y+ + + D Sbjct: 251 SDFQLRLSGAQRVYVRPNAFNEATFALEAGVKILKVLDDHLGIPYDTYMPKLDQIAIPDF 310 Query: 172 HHIPAIQYLLGTPTKKLFTERPRVNEWVAE 201 + L T ++ P V+ + + Sbjct: 311 AAGAMENWGLVTYREQALLFNPAVSTYRGK 340 >3W0K-A nrPDB Length = 330 Score = 28.2 bits (61), Expect = 2.7, Method: Composition-based stats. Identities = 32/213 (15%), Positives = 64/213 (30%), Gaps = 25/213 (11%) Query: 8 GHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFE 67 G ++ L L E +F + V+ + + F NP +V FE DL L E Sbjct: 17 GREPEPPDKKALDFLAETGFNFVRIPVDYRFWTRNFDYF---NPDKKV--FEYIDLYLRE 71 Query: 68 SRAITQYIA-HRYENQGTNLLQTDSKN-------ISQYAIMAIGMQVEDHQFDPVASKLA 119 A ++ + + G + + D + +Q + + L+ Sbjct: 72 CSARNIHMCLNLHRAPGYCINRNDIERDNLWLDKRAQDGFVYQWELFAKRYKGVSSKFLS 131 Query: 120 FEQIFKS------IYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHH 173 F+ + + +++ + K+ E + L G + +L H Sbjct: 132 FDLVNEPPNIGQYGLTRENHASLIIRTVEAIRKIDPDREIVIDG---LGGGNIAMPELAH 188 Query: 174 IPAIQYLLGTPTKKLFTERPRVNEWVAEITKRP 206 + + G T W P Sbjct: 189 LGVVHSGRG-YQPMALTHYQ--ASWWDGHKGLP 218 >3NZN-A nrPDB Length = 103 Score = 28.2 bits (61), Expect = 3.0, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 17/34 (50%) Query: 2 AGIKVFGHPASIATRRVLIALHEKNLDFELVHVE 35 + ++G + ++ L + +DF+ V+V+ Sbjct: 22 GKVIMYGLSTCVWCKKTKKLLTDLGVDFDYVYVD 55 >3ZIT-A nrPDB Length = 78 Score = 27.8 bits (60), Expect = 3.3, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 13/34 (38%) Query: 1 MAGIKVFGHPASIATRRVLIALHEKNLDFELVHV 34 M I+V+ P V L N+ +E V Sbjct: 1 MKKIEVYAQPDCPPCVIVKEFLKHNNVAYEEFDV 34 >1HH2-P nrPDB Length = 344 Score = 27.4 bits (59), Expect = 4.2, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%) Query: 124 FKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGT 183 + + G T V+ + E RL + +++ GE DL + I + T Sbjct: 130 YSELKGTVTTAEVIRVMGEWADIRIGKLETRLPKKEWIPGEEIKAGDLVKVYIIDVVKTT 189 Query: 184 PTKKLFTER 192 K+ R Sbjct: 190 KGPKILVSR 198 >6HIV-Cd nrPDB Length = 440 Score = 26.6 bits (57), Expect = 7.2, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 30/77 (38%), Gaps = 2/77 (2%) Query: 30 ELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFE--SRAITQYIAHRYENQGTNLL 87 E + EL K N GQ+P EDGD + E ++ ++A ++ Sbjct: 158 EHIDKELDKYVAGKNEPYPLNFVGQMPFLEDGDGNIVEVPESLLSNHMAEHPDSTAKPHE 217 Query: 88 QTDSKNISQYAIMAIGM 104 S +IS+ A M Sbjct: 218 PHTSSSISEAAAFEERM 234 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.128 0.332 Lambda K H 0.267 0.0389 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,520,095 Number of Sequences: 36641 Number of extensions: 278344 Number of successful extensions: 1257 Number of sequences better than 10.0: 165 Number of HSP's better than 10.0 without gapping: 227 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 761 Number of HSP's gapped (non-prelim): 275 length of query: 212 length of database: 10,336,785 effective HSP length: 93 effective length of query: 119 effective length of database: 6,929,172 effective search space: 824571468 effective search space used: 824571468 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 57 (26.6 bits)