BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P46109 (303 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2LQW-A nrPDB 631 0.0 2EYZ-A nrPDB 343 5e-95 3QWY-A nrPDB 110 7e-25 1GRI-A nrPDB 71 4e-13 4XEY-B nrPDB 61 6e-10 2FO0-A nrPDB 60 9e-10 6AMW-A nrPDB 60 1e-09 3T04-A nrPDB 59 2e-09 2ABL-A nrPDB 57 1e-08 5VEI-A nrPDB 54 7e-08 1K9A-A nrPDB 54 1e-07 2H8H-A nrPDB 53 2e-07 1AD5-A nrPDB 53 2e-07 6F3F-A nrPDB 53 2e-07 2KK6-A nrPDB 53 2e-07 6F55-A nrPDB 53 2e-07 6CMQ-A nrPDB 52 2e-07 4H1O-A nrPDB 52 2e-07 1N5Z-A nrPDB 51 5e-07 2V1R-A nrPDB 51 6e-07 4BNE-A nrPDB 50 2e-06 3HAJ-A nrPDB 50 2e-06 5U06-A nrPDB 49 2e-06 2AUG-A nrPDB 49 3e-06 4XI2-A nrPDB 49 3e-06 1MIL-A nrPDB 47 8e-06 1NM7-A nrPDB 47 8e-06 2CS0-A nrPDB 47 1e-05 5M6U-B nrPDB 45 3e-05 3PS5-A nrPDB 45 3e-05 2B3O-A nrPDB 45 3e-05 2X3W-D nrPDB 45 3e-05 4FL3-A nrPDB 45 4e-05 2CRH-A nrPDB 45 6e-05 2KBT-A nrPDB 44 7e-05 2YUP-A nrPDB 44 1e-04 1NRV-A nrPDB 44 1e-04 4XZ1-A nrPDB 43 2e-04 1K4U-S nrPDB 43 2e-04 2OZO-A nrPDB 43 2e-04 2LCT-A nrPDB 42 2e-04 3GF9-A nrPDB 42 3e-04 2ED1-A nrPDB 42 4e-04 4N78-F nrPDB 42 5e-04 4JGH-A nrPDB 41 7e-04 2HDV-A nrPDB 41 7e-04 1A81-A nrPDB 40 0.001 3JV3-A nrPDB 40 0.001 2YDL-A nrPDB 40 0.001 2RQT-A nrPDB 40 0.001 2K6D-A nrPDB 40 0.002 2K9G-A nrPDB 40 0.002 2ED0-A nrPDB 40 0.002 1GCQ-A nrPDB 40 0.002 2XKX-A nrPDB 40 0.002 1I07-A nrPDB 39 0.002 3EHQ-A nrPDB 39 0.002 2O2O-A nrPDB 39 0.003 1GBQ-A nrPDB 39 0.003 6C7Y-B nrPDB 39 0.003 2VIF-A nrPDB 39 0.003 2PLE-A nrPDB 39 0.004 5XHZ-A nrPDB 39 0.004 1WXU-A nrPDB 39 0.004 1UEC-A nrPDB 38 0.004 1WI7-A nrPDB 38 0.005 4M4Z-A nrPDB 38 0.005 2DYB-A nrPDB 38 0.005 2DA9-A nrPDB 38 0.006 4E93-A nrPDB 37 0.008 2PZ1-A nrPDB 37 0.008 2HSP-A nrPDB 37 0.009 1OV3-A nrPDB 37 0.011 2DLM-A nrPDB 37 0.012 1UE9-A nrPDB 37 0.013 1RPY-A nrPDB 37 0.013 5NXJ-A nrPDB 37 0.015 4MT6-A nrPDB 37 0.015 2ENM-A nrPDB 36 0.018 1UUS-A nrPDB 36 0.019 1X69-A nrPDB 36 0.022 2NWM-A nrPDB 36 0.022 3ULR-B nrPDB 36 0.023 1Z9Q-A nrPDB 35 0.028 1W6X-A nrPDB 35 0.029 2JT4-A nrPDB 35 0.051 1YWO-A nrPDB 34 0.090 2V1Q-A nrPDB 34 0.093 5O2M-A nrPDB 33 0.11 2VKN-A nrPDB 33 0.11 5O2P-A nrPDB 33 0.19 2DJQ-A nrPDB 33 0.21 2IZV-A nrPDB 32 0.25 2RQW-A nrPDB 32 0.27 5F3Y-A nrPDB 32 0.28 1M27-A nrPDB 32 0.30 5O2Q-A nrPDB 32 0.34 2KYM-A nrPDB 32 0.34 1KA6-A nrPDB 32 0.35 2MIO-A nrPDB 32 0.45 1UGV-A nrPDB 31 0.60 5JMQ-A nrPDB 31 0.67 1UHF-A nrPDB 31 0.69 2EQI-A nrPDB 31 0.78 2DMO-A nrPDB 31 0.85 4IIO-A nrPDB 30 1.4 4WSI-A nrPDB 30 1.7 2GGS-A nrPDB 30 1.7 2CT4-A nrPDB 29 2.4 2BBU-A nrPDB 29 2.6 1RM6-B nrPDB 29 2.7 2HMH-A nrPDB 29 3.0 6C5X-D nrPDB 28 3.3 2CUC-A nrPDB 28 3.3 1XA6-A nrPDB 28 3.4 2CUD-A nrPDB 28 3.4 1J3T-A nrPDB 28 3.6 4GL9-E nrPDB 28 4.0 6AT4-A nrPDB 28 4.4 3ORG-A nrPDB 28 6.5 1BB9-A nrPDB 28 6.7 1MV3-A nrPDB 27 8.6 3CXL-A nrPDB 27 9.0 >2LQW-A nrPDB Length = 303 Score = 631 bits (1627), Expect = 0.0, Method: Compositional matrix adjust. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH Sbjct: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 Query: 61 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT 120 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT Sbjct: 61 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT 120 Query: 121 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 180 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK Sbjct: 121 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 180 Query: 181 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA 240 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA Sbjct: 181 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA 240 Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD Sbjct: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 Query: 301 ENE 303 ENE Sbjct: 301 ENE 303 >2EYZ-A nrPDB Length = 304 Score = 343 bits (880), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 181/323 (56%), Positives = 216/323 (66%), Gaps = 45/323 (13%) Query: 3 SARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYI 62 + FDS +RS+WY G +SRQEA LQGQRHG+FLVRDSST PGDYVLSVSENSRVSHYI Sbjct: 2 AGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYI 61 Query: 63 IN-----------------SLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRY 105 IN + R +IGDQEFD LPALLEFYKIHYLDTTTLIEP R Sbjct: 62 INSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR- 120 Query: 106 PSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN 165 S + ++ EYVR L+DF GND EDLPFKKG+IL I +KPEEQWW+A + Sbjct: 121 ------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAED 174 Query: 166 KDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAV 219 +G+ GMIPVPYVEK V + G + G PEP YAQP TPLP + Sbjct: 175 SEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPG-PYAQPSVNTPLPNL 233 Query: 220 SGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEV 279 QNGP++A+ IQKRVP AYDKTALALEVG++VKVT++N++GQWEGE Sbjct: 234 --------------QNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGEC 279 Query: 280 NGRKGLFPFTHVKIFDPQNPDEN 302 NG++G FPFTHV++ D QNP+E+ Sbjct: 280 NGKRGHFPFTHVRLLDQQNPEED 302 >3QWY-A nrPDB Length = 308 Score = 110 bits (275), Expect = 7e-25, Method: Compositional matrix adjust. Identities = 91/306 (29%), Positives = 139/306 (45%), Gaps = 45/306 (14%) Query: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRH---GMFLVRDSSTCPGDYVLSV---SE 54 M++ FD + ++Y +SR+EA +L G+ G FL+RDSS PG+Y L+V E Sbjct: 30 MTTNGFDPFEWRSFYFPGMSREEAH-KLLGEPQVSIGTFLMRDSSR-PGEYSLTVREADE 87 Query: 55 NSRVSHYII-------NSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPS 107 + V HY+I + KI +Q F +PALL +K+ L +L+ Y Sbjct: 88 GNAVCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTEASLLAA---YKK 144 Query: 108 PPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKD 167 P +E V + F G DLPF++GE L I+ K + WW ARN Sbjct: 145 PI---------------IEVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNAL 189 Query: 168 GRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAI 227 G G++P YV+ + H +R S + + + A + S + Sbjct: 190 GTTGLVPANYVQIQMEF-----HNDRTSKGASQSSIGSSGGGAERFS--SASTSSDNIEL 242 Query: 228 TPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFP 287 P P AK RVP AYD T L ++ G V VT+ NG ++ E++G+ G P Sbjct: 243 QP-----RLPAKAKVTFDRVPNAYDPTQLRVKKGQTVLVTQKMSNGMYKAELDGQIGSVP 297 Query: 288 FTHVKI 293 T+++ Sbjct: 298 HTYLRF 303 >1GRI-A nrPDB Length = 217 Score = 71.2 bits (173), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 46/172 (26%), Positives = 86/172 (50%), Gaps = 16/172 (9%) Query: 14 WYMGPVSRQEAQTRLQGQRH-GMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 W+ G + R +A+ L QRH G FL+R+S + PGD+ LSV + V H+ + ++ Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119 Query: 73 IGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLY 132 + +F+ L L+++++ +T + + + V P PT YV+ L+ Sbjct: 120 LWVVKFNSLNELVDYHR------STSVSRNQQIFLRDIEQV--PQQPT------YVQALF 165 Query: 133 DFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 DF + +L F++G+ + +++ + WW G+ GM P YV + R+ Sbjct: 166 DFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH-GQTGMFPRNYVTPVNRN 216 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 132 YDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 YDF ++L FK+G+IL ++ + +Q W +G+ G IP Y+E Sbjct: 7 YDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 54 >4XEY-B nrPDB Length = 408 Score = 60.8 bits (146), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 46/134 (34%), Positives = 66/134 (49%), Gaps = 17/134 (12%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYII 63 A +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY I Sbjct: 2 ASVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 61 Query: 64 NSLPNRRFKIGDQ-EFDHLPALLEFYKIHYLDT------TTLIEPAPRYPSPPMGSVSAP 116 N+ + + + + F+ L L +H+ T TTL PAP+ P + VS P Sbjct: 62 NTASDGKLYVSSESRFNTLAEL-----VHHHSTVADGLITTLHYPAPKRNKPTVYGVS-P 115 Query: 117 NLPTAEDNLEYVRT 130 N D E RT Sbjct: 116 NY----DKWEMERT 125 >2FO0-A nrPDB Length = 495 Score = 60.5 bits (145), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 45/131 (34%), Positives = 65/131 (49%), Gaps = 17/131 (12%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSL 66 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 97 NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA 156 Query: 67 PNRRFKIGDQ-EFDHLPALLEFYKIHYLDT------TTLIEPAPRYPSPPMGSVSAPNLP 119 + + + + F+ L L +H+ T TTL PAP+ P + VS PN Sbjct: 157 SDGKLYVSSESRFNTLAEL-----VHHHSTVADGLITTLHYPAPKRNKPTVYGVS-PNY- 209 Query: 120 TAEDNLEYVRT 130 D E RT Sbjct: 210 ---DKWEMERT 217 Score = 28.1 bits (61), Expect = 4.9, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEE-QWWSARNKDGRVGMIPVPYVEKLVRSSPHG- 188 LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ + H Sbjct: 46 LYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYITPVNSLEKHSW 104 Query: 189 KHG--NRNSNSY 198 HG +RN+ Y Sbjct: 105 YHGPVSRNAAEY 116 >6AMW-A nrPDB Length = 255 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 12/115 (10%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSL 66 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 139 NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA 198 Query: 67 PNRRFKIGDQ-EFDHLPALLEFYKIHYLDT------TTLIEPAPRYPSPPMGSVS 114 + + + + F+ L L +H+ T TTL PAP+ P + VS Sbjct: 199 SDGKLYVSSESRFNTLAEL-----VHHHSTVADGLITTLHYPAPKRNKPTVYGVS 248 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 130 TLYDFPGNDAEDLPFKKGEILVIIEKPEE-QWWSARNKDGRVGMIPVPYV 178 LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ Sbjct: 87 ALYDFVASGDNTLSITKGEKLRVLGYNHNGEWAEAQTKNGQ-GWVPSNYI 135 >3T04-A nrPDB Length = 123 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 39/115 (33%), Positives = 59/115 (51%), Gaps = 12/115 (10%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSL 66 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 11 NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA 70 Query: 67 PNRRFKIGDQ-EFDHLPALLEFYKIHYLDT------TTLIEPAPRYPSPPMGSVS 114 + + + + F+ L L +H+ T TTL PAP+ P + VS Sbjct: 71 SDGKLYVSSESRFNTLAEL-----VHHHSTVADGLITTLHYPAPKRNKPTVYGVS 120 >2ABL-A nrPDB Length = 163 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 12/104 (11%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSL 66 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 65 NSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTA 124 Query: 67 PNRRFKIGDQ-EFDHLPALLEFYKIHYLDT------TTLIEPAP 103 + + + + F+ L L +H+ T TTL PAP Sbjct: 125 SDGKLYVSSESRFNTLAEL-----VHHHSTVADGLITTLHYPAP 163 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEE-QWWSARNKDGRVGMIPVPYV 178 LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ Sbjct: 14 LYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYI 61 >5VEI-A nrPDB Length = 110 Score = 53.9 bits (128), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 1/64 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187 + +YDF +++L FKKG+ + I+ K ++ W+ + GRVG+ P+ YVEKL S+ Sbjct: 37 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEH-HGRVGIFPISYVEKLTGSAAA 95 Query: 188 GKHG 191 + G Sbjct: 96 LRTG 99 Score = 31.6 bits (70), Expect = 0.39, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 23/37 (62%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 L+ + GD V + R +EGE +GR G+FP ++V+ Sbjct: 51 LSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVE 87 >1K9A-A nrPDB Length = 450 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 27/75 (36%), Positives = 43/75 (57%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 W+ G ++R++A+ L G+FLVR+S+ PGDY L VS +V HY I ++ Sbjct: 82 WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSID 141 Query: 74 GDQEFDHLPALLEFY 88 + F++L L+E Y Sbjct: 142 EEVYFENLMQLVEHY 156 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 1/50 (2%) Query: 132 YDFPGNDAEDLPFKKGEILVIIEKPEE-QWWSARNKDGRVGMIPVPYVEK 180 Y+F G +DLPF KG++L I+ ++ W+ A+NK GR G+IP YV+K Sbjct: 18 YNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQK 67 >2H8H-A nrPDB Length = 535 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 8/93 (8%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRH--GMFLVRDSSTCPGDYVLSVS--ENSR---VS 59 DS WY G ++R+E++ L + G FLVR+S T G Y LSVS +N++ V Sbjct: 143 DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 202 Query: 60 HYIINSLPNRRFKIGDQ-EFDHLPALLEFYKIH 91 HY I L + F I + +F+ L L+ +Y H Sbjct: 203 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH 235 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/49 (44%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPVPYV 178 LYD+ DL FKKGE L I+ E WW A + G+ G IP YV Sbjct: 91 LYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 139 >1AD5-A nrPDB Length = 438 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 8/94 (8%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQ--GQRHGMFLVRDSSTCPGDYVLSV-----SENS 56 AR DS + W+ +SR++A+ +L G G F++RDS T G Y LSV + Sbjct: 56 ARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGD 115 Query: 57 RVSHYIINSLPNRRFKIGDQE-FDHLPALLEFYK 89 V HY I +L N F I + F L L++ YK Sbjct: 116 TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYK 149 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 2/55 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRV-GMIPVPYVEKL 181 V LYD+ EDL F+KG+ +V++E+ E WW AR+ R G IP YV ++ Sbjct: 5 VVALYDYEAIHHEDLSFQKGDQMVVLEESGE-WWKARSLATRKEGYIPSNYVARV 58 >6F3F-A nrPDB Length = 455 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/93 (36%), Positives = 50/93 (53%), Gaps = 8/93 (8%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRH--GMFLVRDSSTCPGDYVLSVS--ENSR---VS 59 DS WY G ++R+E++ L + G FLVR+S T G Y LSVS +N++ V Sbjct: 63 DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 122 Query: 60 HYIINSLPNRRFKIGDQ-EFDHLPALLEFYKIH 91 HY I L + F I + +F+ L L+ +Y H Sbjct: 123 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKH 155 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 22/49 (44%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPVPYV 178 LYD+ DL FKKGE L I+ E WW A + G+ G IP YV Sbjct: 11 LYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 59 >2KK6-A nrPDB Length = 116 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 7/86 (8%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 WY G + R EAQ L+ Q G FLVR+S PG+YVLSV + + H+II + N ++ Sbjct: 19 WYHGAIPRIEAQELLKKQ--GDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDN-MYRF 75 Query: 74 GDQEFDHLPALLEFYKIHYLDTTTLI 99 F ++P L++ H+ T +I Sbjct: 76 EGTGFSNIPQLID----HHYTTKQVI 97 >6F55-A nrPDB Length = 67 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 26/55 (47%), Positives = 35/55 (63%), Gaps = 1/55 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 VR LYD+ G +A++L FK GE L+ I + +EQ W R G VG+ P YVEK+ Sbjct: 8 VRALYDYTGQEADELSFKAGEELMKISEEDEQGWCKGRLLTGHVGLYPANYVEKV 62 >6CMQ-A nrPDB Length = 427 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 11/87 (12%) Query: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSE----------NSRVSHYI 62 W+ G +S +EA+ L + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 10 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 69 Query: 63 INSLPNRRFKIGDQEFDHLPALLEFYK 89 I + G + FD L L+E YK Sbjct: 70 IRCQELKYDVGGGERFDSLTDLVEHYK 96 >4H1O-A nrPDB Length = 560 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 11/87 (12%) Query: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSE----------NSRVSHYI 62 W+ G +S +EA+ L + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 133 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 192 Query: 63 INSLPNRRFKIGDQEFDHLPALLEFYK 89 I + G + FD L L+E YK Sbjct: 193 IRCQELKYDVGGGERFDSLTDLVEHYK 219 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 31/59 (52%) Query: 34 GMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQEFDHLPALLEFYKIHY 92 G FL R S + PGD+ LSV N V+H I + G ++F L L+++Y H+ Sbjct: 48 GSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGGYYDLYGGEKFATLAELVQYYMEHH 106 >1N5Z-A nrPDB Length = 92 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 6/71 (8%) Query: 119 PTAEDNLEYVRTLYDF-PGNDAEDLPFKKGEILVIIEKPE-----EQWWSARNKDGRVGM 172 P LE+ R LYDF P N ++ KKG+++ I+ K + WW R K+G +G Sbjct: 8 PIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGY 67 Query: 173 IPVPYVEKLVR 183 IP Y+E + R Sbjct: 68 IPYNYIEIIKR 78 >2V1R-A nrPDB Length = 80 Score = 50.8 bits (120), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 6/71 (8%) Query: 119 PTAEDNLEYVRTLYDF-PGNDAEDLPFKKGEILVIIEKPE-----EQWWSARNKDGRVGM 172 P LE+ R LYDF P N ++ KKG+++ I+ K + WW R K+G +G Sbjct: 8 PIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGY 67 Query: 173 IPVPYVEKLVR 183 IP Y+E + R Sbjct: 68 IPYNYIEIIKR 78 >4BNE-A nrPDB Length = 457 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 23/53 (43%), Positives = 33/53 (62%), Gaps = 1/53 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVE 179 VR LYD+ G + ++L FK G+ L +E +EQ W R +G+VG+ P YVE Sbjct: 402 VRALYDYEGQEQDELSFKAGDELTKMENEDEQGWCKGRLDNGQVGLYPANYVE 454 >3HAJ-A nrPDB Length = 486 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 34/55 (61%), Gaps = 1/55 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 VR LYD+ G + ++L FK G+ L +E +EQ W R +G+VG+ P YVE + Sbjct: 431 VRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485 >5U06-A nrPDB Length = 120 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 33/87 (37%), Positives = 50/87 (57%), Gaps = 13/87 (14%) Query: 14 WYMGPVSRQEAQTRLQGQR---HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR 70 W+ G +SR+E+Q RL GQ+ G+FLVR+S P +VLS+ +V HY+I LP+ Sbjct: 19 WFHGRISREESQ-RLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLI--LPSEE 75 Query: 71 -----FKI--GDQEFDHLPALLEFYKI 90 F + G F L L+EF+++ Sbjct: 76 EGRLYFSMDDGQTRFTDLLQLVEFHQL 102 >2AUG-A nrPDB Length = 126 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 7/84 (8%) Query: 14 WYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN--- 68 W+ +SR EAQ + QG G+FLVRDS + P +VLS+S ++ H+ I + + Sbjct: 28 WFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPVEDDGE 87 Query: 69 --RRFKIGDQEFDHLPALLEFYKI 90 G F L L+EFY++ Sbjct: 88 MFHTLDDGHTRFTDLIQLVEFYQL 111 >4XI2-A nrPDB Length = 446 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 23/54 (42%), Positives = 33/54 (61%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYV 178 L+ V LYD+ +A DL +KGE I+E+ WW AR+K+G+ G IP Y+ Sbjct: 3 LKKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYI 56 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/91 (28%), Positives = 49/91 (53%), Gaps = 9/91 (9%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQ-RHGMFLVRDSSTCPGDYVLSVSENSR------VS 59 DS + WY ++R +A+ L+ + + G F+VRDSS G Y +SV S + Sbjct: 61 DSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGEPQGVIR 119 Query: 60 HYIINSLPNRRFKIGDQE-FDHLPALLEFYK 89 HY++ S P ++ + ++ F +P L+ +++ Sbjct: 120 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQ 150 >1MIL-A nrPDB Length = 104 Score = 47.4 bits (111), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 26/80 (32%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 W+ G +SR+EA+ LQ +G FLVR+S+T PG YVL+ ++ + H ++ P + Sbjct: 9 WFHGKLSRREAEALLQ--LNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVD-PEGVVRT 65 Query: 74 GDQEFDHLPALLEFYKIHYL 93 D F+ + L+ ++ ++L Sbjct: 66 KDHRFESVSHLISYHMDNHL 85 >1NM7-A nrPDB Length = 69 Score = 47.4 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 6/59 (10%) Query: 127 YVRTLYDF-PGNDAEDLPFKKGEILVIIEKPE-----EQWWSARNKDGRVGMIPVPYVE 179 + R LYDF P N ++ KKG+++ I+ K + WW R K+G +G IP Y+E Sbjct: 9 FARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIE 67 >2CS0-A nrPDB Length = 119 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 43/78 (55%), Gaps = 3/78 (3%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 W+ G +SR++A+ L+ Q G FL+R S + G Y LS S H+++ L + F I Sbjct: 18 WFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFMI 76 Query: 74 GDQEFDH--LPALLEFYK 89 ++ H L AL+ F++ Sbjct: 77 PGEKVAHTSLDALVTFHQ 94 >5M6U-B nrPDB Length = 724 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Query: 10 DRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 D W +G +R +A+ L+G+R G FLVR+SS G Y SV + V H +IN Sbjct: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVIN 673 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSST-CPGDYVLSV 52 + WY G +SR+E +L+ G FLVRD+ST GDY L++ Sbjct: 331 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTL 372 >3PS5-A nrPDB Length = 595 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 10/86 (11%) Query: 14 WYMGPVSRQEAQTRLQGQRH-GMFLVRDSSTCPGDYVLSVSENS---------RVSHYII 63 WY G +S +A+T LQ + FLVR+S + PGD+VLSV + RV+H + Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKV 169 Query: 64 NSLPNRRFKIGDQEFDHLPALLEFYK 89 R G + FD L L+E +K Sbjct: 170 MCEGGRYTVGGLETFDSLTDLVEHFK 195 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Query: 14 WYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 W+ +S +A+T L+G+ HG FL R S GD+ LSV +V+H I + + Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63 Query: 73 IGDQEFDHLPALLEFY 88 G ++F L L+E+Y Sbjct: 64 YGGEKFATLTELVEYY 79 >2B3O-A nrPDB Length = 532 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 10/86 (11%) Query: 14 WYMGPVSRQEAQTRLQGQRH-GMFLVRDSSTCPGDYVLSVSENS---------RVSHYII 63 WY G +S +A+T LQ + FLVR+S + PGD+VLSV + RV+H + Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKV 169 Query: 64 NSLPNRRFKIGDQEFDHLPALLEFYK 89 R G + FD L L+E +K Sbjct: 170 MCEGGRYTVGGLETFDSLTDLVEHFK 195 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 1/76 (1%) Query: 14 WYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 W+ +S +A+T L+G+ HG FL R S GD+ LSV +V+H I + + Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63 Query: 73 IGDQEFDHLPALLEFY 88 G ++F L L+E+Y Sbjct: 64 YGGEKFATLTELVEYY 79 >2X3W-D nrPDB Length = 60 Score = 45.1 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 21/55 (38%), Positives = 33/55 (60%), Gaps = 1/55 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 VR LYD+ G + ++L FK G+ L + + +EQ W R G++G+ P YVE + Sbjct: 6 VRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 60 >4FL3-A nrPDB Length = 635 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 37/143 (25%), Positives = 59/143 (41%), Gaps = 5/143 (3%) Query: 2 SSARFDSSDRSAWYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVS 59 SS DS++ ++ G ++R+EA+ L G G++L+R S G + LSV+ + Sbjct: 3 SSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAH 62 Query: 60 HYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLP 119 HY I N + I PA L Y D + P + P Sbjct: 63 HYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKP-FNRPQGVQPKTGPFE 121 Query: 120 TAEDNL--EYVRTLYDFPGNDAE 140 ++NL EYV+ ++ G E Sbjct: 122 DLKENLIREYVKQTWNLQGQALE 144 >2CRH-A nrPDB Length = 138 Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 43/94 (45%), Gaps = 1/94 (1%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 WY GP+ R A++ L + G FLVR ++ +S+ N V H I + Sbjct: 28 WYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRIT 87 Query: 74 GDQEFDHLPALLEFYKIHYL-DTTTLIEPAPRYP 106 + F L L+EFY+ + L D ++ ++P Sbjct: 88 EKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 121 >2KBT-A nrPDB Length = 142 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 6/61 (9%) Query: 236 GP-VFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQ---WEGEVNGRKGLFPFTHV 291 GP F A + CA D++ L+L+ GDI+K+ +N GQ W GE+ GR G FP +V Sbjct: 1 GPGTFGTAKARYDFCARDRSELSLKEGDIIKI--LNKKGQQGWWRGEIYGRIGWFPSNYV 58 Query: 292 K 292 + Sbjct: 59 E 59 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 1/94 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK-LVRSSP 186 + YDF D +L K+G+I+ I+ K +Q W GR+G P YVE+ P Sbjct: 8 AKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYLP 67 Query: 187 HGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVS 220 G+ +S +Y + TT + A + Sbjct: 68 ETGGGSGSSMTYKLILNGKTLKGETTTEAVDAAT 101 >2YUP-A nrPDB Length = 90 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%) Query: 111 GSVSAPNLPTAEDNLEYVRTL--YDFPGNDAEDLPFKKGEILVIIEKPEEQWWSAR-NKD 167 GS + P LEY + Y F G+ +L F+KGE + +I K E W+ R Sbjct: 1 GSSGSSGKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGT 60 Query: 168 GRVGMIPVPYVE 179 GR G+ P YV+ Sbjct: 61 GRQGIFPASYVQ 72 >1NRV-A nrPDB Length = 105 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 49/86 (56%), Gaps = 11/86 (12%) Query: 14 WYMGPVSRQEAQ--TRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR- 70 W+ G +SR+E+ + QG G+FL+RDS + P +VL++ + ++ ++ I LP Sbjct: 7 WFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQI--LPCEDD 64 Query: 71 ----FKI--GDQEFDHLPALLEFYKI 90 F + G+ +F L L++FY++ Sbjct: 65 GQTFFSLDDGNTKFSDLIQLVDFYQL 90 >4XZ1-A nrPDB Length = 262 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 3/78 (3%) Query: 14 WYMGPVSRQEAQ--TRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRF 71 ++ G +SR EA+ +L G G+FL+R G YVLS+ + R H+ I N + Sbjct: 13 FFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTY 72 Query: 72 KIGDQEFDHLPA-LLEFY 88 I + PA L EFY Sbjct: 73 AIAGGKAHCGPAELCEFY 90 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQ--GQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + +R WY ++R+EA+ +L Q G FL+R G Y LS+ V HY+I+ Sbjct: 160 AHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKE-QGTYALSLIYGKTVYHYLISQ 218 Query: 66 LPNRRFKIGD-QEFDHLPALLEFYKI 90 ++ I + +FD L L+E+ K+ Sbjct: 219 DKAGKYCIPEGTKFDTLWQLVEYLKL 244 >1K4U-S nrPDB Length = 62 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 V L+ + EDL F++G+I++++ K E+W +K G+VG+ P +VE Sbjct: 8 VEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGESK-GKVGIFPKVFVE 58 Score = 27.3 bits (59), Expect = 8.1, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 22/38 (57%), Gaps = 2/38 (5%) Query: 256 LALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVK 292 L + GDI+ V +N +W EGE G+ G+FP V+ Sbjct: 22 LEFQEGDIILVLS-KVNEEWLEGESKGKVGIFPKVFVE 58 >2OZO-A nrPDB Length = 613 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/78 (34%), Positives = 39/78 (50%), Gaps = 3/78 (3%) Query: 14 WYMGPVSRQEAQ--TRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRF 71 ++ G +SR EA+ +L G G+FL+R G YVLS+ + R H+ I N + Sbjct: 10 FFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTY 69 Query: 72 KIGDQEFDHLPA-LLEFY 88 I + PA L EFY Sbjct: 70 AIAGGKAHCGPAELCEFY 87 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQ--GQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + +R WY ++R+EA+ +L Q G FL+R G Y LS+ V HY+I+ Sbjct: 157 AHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKE-QGTYALSLIYGKTVYHYLISQ 215 Query: 66 LPNRRFKIGD-QEFDHLPALLEFYKI 90 ++ I + +FD L L+E+ K+ Sbjct: 216 DKAGKYCIPEGTKFDTLWQLVEYLKL 241 >2LCT-A nrPDB Length = 107 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 35/76 (46%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 WY GP+ R A++ L + G FLVR ++ +S+ N V H I + Sbjct: 11 WYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRIT 70 Query: 74 GDQEFDHLPALLEFYK 89 + F L L+EFY+ Sbjct: 71 EKKAFRGLTELVEFYQ 86 >3GF9-A nrPDB Length = 295 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 V +YD+ N+ ++L F KG+++ ++ K + WW +G G+ P YV+ S P Sbjct: 21 VIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQG-EINGVTGLFPSNYVKMTTDSDP 78 Score = 35.0 bits (79), Expect = 0.036, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 5/61 (8%) Query: 246 RVPCAYDKTA-----LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 +V YD A L+ G ++ V + W+GE+NG GLFP +VK+ +P Sbjct: 20 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPS 79 Query: 301 E 301 + Sbjct: 80 Q 80 >2ED1-A nrPDB Length = 76 Score = 41.6 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWW--SARNKDGRVGMIPVPY 177 ++ + + V+T+YD ++ ++L F +GE++++ + +++WW + R G+ PV + Sbjct: 5 SSGNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSF 64 Query: 178 VEKLVRSSP 186 V L S P Sbjct: 65 VHILSDSGP 73 Score = 28.1 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 27/63 (42%), Gaps = 8/63 (12%) Query: 245 KRVPCAYDKTA-----LALEVGDIVKVTRMNINGQWEGEVNG---RKGLFPFTHVKIFDP 296 +RV YD A L G+++ VT W G + G RKG+FP + V I Sbjct: 11 RRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHILSD 70 Query: 297 QNP 299 P Sbjct: 71 SGP 73 >4N78-F nrPDB Length = 514 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 LE V +YD+ + ++L F++G I+ +I+K ++ W+ +G G+ P YVE ++ Sbjct: 454 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGV-MNGVTGLFPGNYVESIMHY 512 Query: 185 S 185 S Sbjct: 513 S 513 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 5/53 (9%) Query: 245 KRVPCAYDKTA-----LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 ++V YD T L+ + G I+ V + N +G +EG +NG GLFP +V+ Sbjct: 455 EKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 507 >4JGH-A nrPDB Length = 173 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 37/125 (29%), Positives = 66/125 (52%), Gaps = 23/125 (18%) Query: 11 RSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVS-------ENSRVSH--- 60 ++ WY G ++ EA+ +L+ G FL+RDSS DY+L++S N R+ + Sbjct: 20 QTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSS--HSDYLLTISVKTSAGPTNLRIEYQDG 77 Query: 61 -YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPR------YPSPPMGSV 113 + ++S+ + K+ ++FD + L+++Y D T E APR Y + P+ + Sbjct: 78 KFRLDSIICVKSKL--KQFDSVVHLIDYYVQMCKDKRTGPE-APRNGTVHLYLTKPLYT- 133 Query: 114 SAPNL 118 SAP+L Sbjct: 134 SAPSL 138 >2HDV-A nrPDB Length = 111 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 3/81 (3%) Query: 14 WYMGPVSR-QEAQTRLQGQ--RHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR 70 W+ G +SR + AQ L+G HG+FLVR S T G+ VL+ + + H ++ + Sbjct: 11 WFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTFNFQGKAKHLRLSLNAAGQ 70 Query: 71 FKIGDQEFDHLPALLEFYKIH 91 ++ F + +LE +++H Sbjct: 71 CRVQHLHFQSIFDMLEHFRVH 91 >1A81-A nrPDB Length = 254 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 34/137 (24%), Positives = 56/137 (40%), Gaps = 5/137 (3%) Query: 8 SSDRSAWYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 S++ ++ G ++R+EA+ L G G++L+R S G + LSV+ + HY I Sbjct: 1 SANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIER 60 Query: 66 LPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNL 125 N + I PA L Y D + P + P ++NL Sbjct: 61 ELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKP-FNRPQGVQPKTGPFEDLKENL 119 Query: 126 --EYVRTLYDFPGNDAE 140 EYV+ ++ G E Sbjct: 120 IREYVKQTWNLQGQALE 136 >3JV3-A nrPDB Length = 283 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 29/49 (59%), Gaps = 1/49 (2%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 +YD+ + ++L F KG+I+ ++ K + WW G+VG+ P YV+ Sbjct: 8 MYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE-VSGQVGLFPSNYVK 55 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 5/56 (8%) Query: 251 YDKTA-----LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDE 301 YD TA LA G I+ V W+GEV+G+ GLFP +VK+ +P + Sbjct: 9 YDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQ 64 >2YDL-A nrPDB Length = 69 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIFDP 296 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ P Sbjct: 13 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPP 61 >2RQT-A nrPDB Length = 61 Score = 39.7 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 34/56 (60%), Gaps = 2/56 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA--RNKDGRVGMIPVPYVEKL 181 V+T+YD ++ ++L F +GE++++ + +++WW + R G+ PV +V L Sbjct: 4 VKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHIL 59 >2K6D-A nrPDB Length = 62 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIFDP 296 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ P Sbjct: 14 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPP 62 >2K9G-A nrPDB Length = 73 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIFDP 296 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ P Sbjct: 20 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPP 68 >2ED0-A nrPDB Length = 78 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 1/57 (1%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 LE V +YD+ + ++L F++G I+ +I+K ++ W+ +G G+ P YVE + Sbjct: 17 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGV-MNGVTGLFPGNYVESI 72 Score = 35.8 bits (81), Expect = 0.020, Method: Compositional matrix adjust. Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 5/57 (8%) Query: 241 KAIQKRVPCAYDKTA-----LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 ++ ++V YD T L+ + G I+ V + N +G +EG +NG GLFP +V+ Sbjct: 14 RSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 70 >1GCQ-A nrPDB Length = 61 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 YV+ L+DF + +L F++G+ + +++ + WW G+ GM P YV + R+ Sbjct: 4 YVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH-GQTGMFPRNYVTPVNRN 60 >2XKX-A nrPDB Length = 721 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 33/134 (24%), Positives = 58/134 (43%), Gaps = 14/134 (10%) Query: 127 YVRTLYDFP-----GNDAEDLPFKKGEILVIIEKPEEQWWSAR-----NKDGRVGMIPVP 176 Y+R L+D+ G ++ L F+ G++L +I+ +E+WW AR ++ +G IP Sbjct: 429 YIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSK 488 Query: 177 -YVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQN 235 VE+ S K +S S G + +Y +T T + P + P N Sbjct: 489 RRVERREWSRLKAKDWGSSSGSQGREDSVLSY---ETVTQMEVHYARPIIILGPTKDRAN 545 Query: 236 GPVFAKAIQKRVPC 249 + ++ K C Sbjct: 546 DDLLSEFPDKFGSC 559 >1I07-A nrPDB Length = 60 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIP 174 +Y ++ YDF ++ +L K ++L I++ QWW RN G G +P Sbjct: 2 KYAKSKYDFVARNSSELSVMKDDVLEILDD-RRQWWKVRNASGDSGFVP 49 >3EHQ-A nrPDB Length = 222 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 R LY F ++L ++G+I+ I + + WW +K GR G+IP YV + S Sbjct: 18 RALYTFEPRTPDELYIEEGDIIYITDMSDTNWWKGTSK-GRTGLIPSNYVAEQAES 72 Score = 34.7 bits (78), Expect = 0.057, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHV 291 L +E GDI+ +T M+ W+G GR GL P +V Sbjct: 31 LYIEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYV 66 >2O2O-A nrPDB Length = 92 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 17/37 (45%), Positives = 24/37 (64%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 L L+VGDI++V G WEG +NG+ G+FP +K Sbjct: 35 LELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 71 Score = 35.0 bits (79), Expect = 0.038, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 134 FPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 P ND E L K G+I+ ++ + EE WW +G+ GM P ++++L Sbjct: 28 LPQNDDE-LELKVGDIIEVVGEVEEGWWEGV-LNGKTGMFPSNFIKEL 73 >1GBQ-A nrPDB Length = 74 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%) Query: 132 YDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 YDF ++L FK+G+IL ++ + +Q W +G+ G IP Y+E Sbjct: 16 YDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIE 63 >6C7Y-B nrPDB Length = 117 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 5/87 (5%) Query: 10 DRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNR 69 D +Y GP++ A +L+ + G FL+RDS+ + +SV + + IN R Sbjct: 24 DACGFYWGPLTVSAAHEKLKSEPEGTFLIRDSTQKNCFFAISVKTATGPTSIRINFQTGR 83 Query: 70 RFKIGDQE-FDHLPALLEFYKIHYLDT 95 G +E FD L LLE HYL + Sbjct: 84 FSLDGSKETFDCLFKLLE----HYLSS 106 >2VIF-A nrPDB Length = 141 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 21/46 (45%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 11 RSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENS 56 + WY GP++R EA+ +L G FLVRDSS Y+LS+S S Sbjct: 23 KQGWYWGPITRWEAEGKLANVPDGSFLVRDSS--DDRYLLSLSFRS 66 >2PLE-A nrPDB Length = 105 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%) Query: 14 WYMGPVSRQEAQTRLQGQ-RHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 WY ++R +A+ L R G FLVR + P Y +S ++ H + + Sbjct: 11 WYHASLTRAQAEHMLMRVPRDGAFLVRKRNE-PNSYAISFRAEGKIKHCRVQQ-EGQTVM 68 Query: 73 IGDQEFDHLPALLEFYKIH 91 +G+ EFD L L+ +Y+ H Sbjct: 69 LGNSEFDSLVDLISYYEKH 87 >5XHZ-A nrPDB Length = 66 Score = 38.5 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 17/37 (45%), Positives = 24/37 (64%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 L L+VGDI++V G WEG +NG+ G+FP +K Sbjct: 26 LELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 62 Score = 34.3 bits (77), Expect = 0.064, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 134 FPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 P ND E L K G+I+ ++ + EE WW +G+ GM P ++++L Sbjct: 19 LPQNDDE-LELKVGDIIEVVGEVEEGWWEGV-LNGKTGMFPSNFIKEL 64 >1WXU-A nrPDB Length = 93 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 38/72 (52%), Gaps = 4/72 (5%) Query: 114 SAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVII---EKPEEQWWSARNKDGR- 169 S N + ED+ R YDF E++ F+ G++L + ++P+ + W + DG+ Sbjct: 6 SGTNWASGEDDHVVARAEYDFVAVSDEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQT 65 Query: 170 VGMIPVPYVEKL 181 G+IP YV+ L Sbjct: 66 TGLIPANYVKIL 77 >1UEC-A nrPDB Length = 193 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 35/168 (20%), Positives = 61/168 (36%), Gaps = 44/168 (26%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 L+ R + D+ ++ G+++ ++EK E WW + K R G IP ++E L Sbjct: 11 LQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-GWIPASFLEPL--D 67 Query: 185 SPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQ 244 SP +T P P +G P AI + + V Sbjct: 68 SPD-----------------------ETEDPEPNYAGEPYVAIKAYTAVEGDEV------ 98 Query: 245 KRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 +L G+ V+V ++G W + G FP +++ Sbjct: 99 ------------SLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 134 Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 7/72 (9%) Query: 235 NGPVFAKAIQKRVPCAYDKTA---LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHV 291 GP+ + R Y+KT+ +AL GD+V+V + +G W ++ ++G P + + Sbjct: 6 TGPIILQTY--RAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFL 63 Query: 292 KIFDPQNPDENE 303 + D +PDE E Sbjct: 64 EPLD--SPDETE 73 >1WI7-A nrPDB Length = 68 Score = 38.1 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 17/37 (45%), Positives = 24/37 (64%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 L L+VGDI++V G WEG +NG+ G+FP +K Sbjct: 24 LELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 60 Score = 33.9 bits (76), Expect = 0.083, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 134 FPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 P ND E L K G+I+ ++ + EE WW +G+ GM P ++++L Sbjct: 17 LPQNDDE-LELKVGDIIEVVGEVEEGWWEGV-LNGKTGMFPSNFIKEL 62 >4M4Z-A nrPDB Length = 170 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 8/96 (8%) Query: 13 AWYMGPVSRQEAQTRLQ--GQRHGMFLVRDSSTCPGDYVLSV-----SENSRVSHYIINS 65 W +SR++A+ L G G FL+R+S T G Y LSV + R+ HY I+ Sbjct: 70 GWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHC 129 Query: 66 LPNRRFKIGDQ-EFDHLPALLEFYKIHYLDTTTLIE 100 L N I + F L AL++ Y D L++ Sbjct: 130 LDNGWLYISPRLTFPSLQALVDHYSELADDICCLLK 165 >2DYB-A nrPDB Length = 341 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 36/75 (48%), Gaps = 8/75 (10%) Query: 107 SPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNK 166 SP SV P AE L+DF GN +L FK G+++ ++ + + W + Sbjct: 163 SPQGNSVDRMAAPRAE-------ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVR 215 Query: 167 DGRVGMIPVPYVEKL 181 G G+ P+ +V+ L Sbjct: 216 -GATGIFPLSFVKIL 229 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 253 KTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVKIF 294 K L + GD++ + IN W EG V G G+FP + VKI Sbjct: 188 KLELNFKAGDVIFLLS-RINKDWLEGTVRGATGIFPLSFVKIL 229 >2DA9-A nrPDB Length = 70 Score = 37.7 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 2/47 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIF 294 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ Sbjct: 18 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLL 64 >4E93-A nrPDB Length = 377 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 8/82 (9%) Query: 14 WYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKI 73 WY G + R E L G FLVR+S +YVLSV + H+II SL N +++ Sbjct: 15 WYHGAIPRAEVAELLV--HSGDFLVRESQG-KQEYVLSVLWDGLPRHFIIQSLDN-LYRL 70 Query: 74 GDQEFDHLPALLEFYKIHYLDT 95 + F +P L++ H L T Sbjct: 71 EGEGFPSIPLLID----HLLST 88 >2PZ1-A nrPDB Length = 466 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 1/68 (1%) Query: 111 GSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRV 170 G A N ++ ++ L+D D ++L FK G+++ +++ +WW R DG Sbjct: 16 GEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGE- 74 Query: 171 GMIPVPYV 178 G P +V Sbjct: 75 GWFPASFV 82 Score = 30.4 bits (67), Expect = 0.99, Method: Compositional matrix adjust. Identities = 25/95 (26%), Positives = 37/95 (38%), Gaps = 11/95 (11%) Query: 199 GIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALAL 258 G +H Y+ P G AI L S V A+A+ V D L Sbjct: 1 GAMSSSHHYSHPG--------GGGEQLAINELISD-GSVVCAEALWDHVT--MDDQELGF 49 Query: 259 EVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 + GD+++V W G V +G FP + V++ Sbjct: 50 KAGDVIEVMDATNREWWWGRVADGEGWFPASFVRL 84 >2HSP-A nrPDB Length = 71 Score = 37.0 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187 V+ L+D+ ++L F K I+ +EK E WW + P YVE++V +P Sbjct: 9 VKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMV--NPE 66 Query: 188 GKH 190 G H Sbjct: 67 GIH 69 >1OV3-A nrPDB Length = 138 Score = 37.0 bits (84), Expect = 0.011, Method: Compositional matrix adjust. Identities = 35/168 (20%), Positives = 61/168 (36%), Gaps = 44/168 (26%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 L+ R + D+ ++ G+++ ++EK E WW + K R G IP ++E L Sbjct: 11 LQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-GWIPASFLEPL--D 67 Query: 185 SPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQ 244 SP +T P P +G P AI + + V Sbjct: 68 SPD-----------------------ETEDPEPNYAGEPYVAIKAYTAVEGDEV------ 98 Query: 245 KRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 +L G+ V+V ++G W + G FP +++ Sbjct: 99 ------------SLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 134 Score = 36.2 bits (82), Expect = 0.020, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 5/70 (7%) Query: 237 PVFAKAIQKRVPCAYDKTA---LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 P F R Y+KT+ +AL GD+V+V + +G W ++ ++G P + ++ Sbjct: 6 PEFIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEP 65 Query: 294 FDPQNPDENE 303 D +PDE E Sbjct: 66 LD--SPDETE 73 >2DLM-A nrPDB Length = 68 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 R +DF ++L +KG+I+ I ++ ++ W + GR+G+ P YVE L Sbjct: 10 ARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHH-GRLGIFPANYVEVL 62 Score = 32.0 bits (71), Expect = 0.35, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 2/40 (5%) Query: 256 LALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVKIF 294 L L+ GDIV + + ++ W EGE +GR G+FP +V++ Sbjct: 24 LTLQKGDIVYIHK-EVDKNWLEGEHHGRLGIFPANYVEVL 62 >1UE9-A nrPDB Length = 80 Score = 36.6 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 28/48 (58%), Gaps = 5/48 (10%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGR-----KGLFPFTHVKIFDPQN 298 L+L G ++ + + N +G W+GE+ R KG FP +HVK+ P + Sbjct: 24 LSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSS 71 >1RPY-A nrPDB Length = 114 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 19/50 (38%), Positives = 30/50 (60%), Gaps = 3/50 (6%) Query: 14 WYMGPVSR-QEAQTRLQG--QRHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 W+ G +SR + AQ L G + HG+F++R S T PG+ VL+ + + H Sbjct: 13 WFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKH 62 >5NXJ-A nrPDB Length = 60 Score = 36.6 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 LYD+ +++ F +I+ IE ++ WW K GR G+ P YVE Sbjct: 10 LYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVE 57 Score = 30.8 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 ++ + DI+ M +G W G GR GLFP +V++ Sbjct: 21 ISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 58 >4MT6-A nrPDB Length = 456 Score = 36.6 bits (83), Expect = 0.015, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 7/82 (8%) Query: 216 LPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQW 275 + + G G IT + V A+A+ V A LA + GD++KV + W Sbjct: 1 MQWIRGGSGMLITG-----DSIVSAEAVWDHVTMA--NRELAFKAGDVIKVLDASNKDWW 53 Query: 276 EGEVNGRKGLFPFTHVKIFDPQ 297 G+++ +G FP + V+++ Q Sbjct: 54 WGQIDDEEGWFPASFVRLWVNQ 75 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 28/140 (20%), Positives = 52/140 (37%), Gaps = 14/140 (10%) Query: 141 DLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVR---------SSPHGKHG 191 +L FK G+++ +++ + WW + D G P +V V S H Sbjct: 33 ELAFKAGDVIKVLDASNKDWWWGQIDDEE-GWFPASFVRLWVNQEDGVEEGPSDVQNGHL 91 Query: 192 NRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAY 251 + NS+ + P Q + + + + I L G + K +KR Sbjct: 92 DPNSDCLCLGRPLQNRDQMRANV-INEIMSTERHYIKHLKDICEG--YLKQCRKRRDMFS 148 Query: 252 DKTALALEVGDIVKVTRMNI 271 D+ L + G+I + R + Sbjct: 149 DEQ-LKVIFGNIEDIYRFQM 167 >2ENM-A nrPDB Length = 77 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 6/58 (10%) Query: 128 VRTLYDF---PGNDAEDLPFKKGEILVIIE-KPEEQWWSARNKDGRVGMIPVPYVEKL 181 R +YDF PGN+ +L +GEI+ + W +N G G++P YVE L Sbjct: 12 ARVMYDFAAEPGNN--ELTVTEGEIITVTNPNVGGGWLEGKNNKGEQGLVPTDYVEIL 67 Score = 30.8 bits (68), Expect = 0.73, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 4/48 (8%) Query: 256 LALEVGDIVKVTRMNINGQW-EGEVN-GRKGLFPFTHVKIF--DPQNP 299 L + G+I+ VT N+ G W EG+ N G +GL P +V+I D ++P Sbjct: 27 LTVTEGEIITVTNPNVGGGWLEGKNNKGEQGLVPTDYVEILPNDGKDP 74 >1UUS-A nrPDB Length = 473 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 32/70 (45%), Gaps = 7/70 (10%) Query: 1 MSSARFDSSDRSAWYMGPV----SRQEAQTRLQGQRHGMFLVRDSSTCPGDY---VLSVS 53 M + R+ + W G + RQE LQ Q G F++R S PG + + V Sbjct: 336 MQTLRYQRHISTLWQEGIIYGYMGRQEVNDALQNQDPGTFIIRFSERNPGQFGIAYIGVE 395 Query: 54 ENSRVSHYII 63 +R+ HY++ Sbjct: 396 MPARIKHYLV 405 >1X69-A nrPDB Length = 79 Score = 35.8 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 2/56 (3%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 LYD+ +++ F +I+ IE ++ WW K GR G+ P YVE L +S P Sbjct: 23 LYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVE-LRQSGP 76 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 ++ + DI+ M +G W G GR GLFP +V++ Sbjct: 34 ISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 71 >2NWM-A nrPDB Length = 65 Score = 35.8 bits (81), Expect = 0.022, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 ++ R +DF ++L +KG+I+ I ++ ++ W + GR+G+ P YVE L Sbjct: 1 MKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHH-GRLGIFPANYVEVL 56 Score = 31.6 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 26/40 (65%), Gaps = 2/40 (5%) Query: 256 LALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVKIF 294 L L+ GDIV + + ++ W EGE +GR G+FP +V++ Sbjct: 18 LTLQKGDIVYIHK-EVDKNWLEGEHHGRLGIFPANYVEVL 56 >3ULR-B nrPDB Length = 65 Score = 35.8 bits (81), Expect = 0.023, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 LYD+ +++ F +I+ IE ++ WW K GR G+ P YVE Sbjct: 15 LYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVE 62 Score = 30.4 bits (67), Expect = 0.98, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 ++ + DI+ M +G W G GR GLFP +V++ Sbjct: 26 ISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 63 >1Z9Q-A nrPDB Length = 79 Score = 35.4 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 32/56 (57%), Gaps = 2/56 (3%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 L+DF GN +L FK G+++ ++ + + W + G G+ P+ +V K+++ P Sbjct: 24 LFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVR-GATGIFPLSFV-KILKDFP 77 Score = 31.2 bits (69), Expect = 0.55, Method: Composition-based stats. Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 253 KTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVKIF 294 K L + GD++ + IN W EG V G G+FP + VKI Sbjct: 32 KLELNFKAGDVIFLLS-RINKDWLEGTVRGATGIFPLSFVKIL 73 >1W6X-A nrPDB Length = 60 Score = 35.4 bits (80), Expect = 0.029, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 29/51 (56%), Gaps = 1/51 (1%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 L+DF GN +L FK G+++ ++ + + W + G G+ P+ +V+ L Sbjct: 10 LFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVR-GATGIFPLSFVKIL 59 Score = 31.6 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 253 KTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVKIF 294 K L + GD++ + IN W EG V G G+FP + VKI Sbjct: 18 KLELNFKAGDVIFLLS-RINKDWLEGTVRGATGIFPLSFVKIL 59 >2JT4-A nrPDB Length = 71 Score = 34.7 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 132 YDFPGNDAEDLPFKKGE-ILVIIEKPEEQWWSARNKD-GRVGMIPVPYVEKLVRSSPH 187 YDF ++L K G+ + ++ +K + WW + D G+ G++P ++E VR H Sbjct: 13 YDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVDSGKSGLVPAQFIEP-VRDKKH 69 >1YWO-A nrPDB Length = 64 Score = 33.9 bits (76), Expect = 0.090, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 27/55 (49%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLV 182 V+ L+D+ ++L F K I+ +EK + WW + P YVE+++ Sbjct: 9 VKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEMI 63 >2V1Q-A nrPDB Length = 60 Score = 33.9 bits (76), Expect = 0.093, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 28/50 (56%), Gaps = 2/50 (4%) Query: 132 YDFPGNDAEDLPFKKGE-ILVIIEKPEEQWWSARNKD-GRVGMIPVPYVE 179 YDF ++L K G+ + ++ +K + WW + D G+ G++P ++E Sbjct: 9 YDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVDSGKSGLVPAQFIE 58 >5O2M-A nrPDB Length = 81 Score = 33.5 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 4/49 (8%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEE---QWWSARNKDGRVGMIP 174 + LYD ++L F+KG+I+ ++E+ + WW + GR G++P Sbjct: 11 KALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLC-SLHGRQGIVP 58 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query: 238 VFAKAIQKRVPCAYDKTALALEVGDIVKVTRMN---INGQWEGEVNGRKGLFPFTHVKIF 294 V AKA+ V + D+ L+ GDI+ V + ++G W ++GR+G+ P +KI Sbjct: 8 VLAKALYDNVAESPDE--LSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKIL 65 >2VKN-A nrPDB Length = 70 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 141 DLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 ++ F++ EIL + E +WW AR +G G+IP YV+ + Sbjct: 23 EISFEQNEILQV-SDIEGRWWKARRANGETGIIPSNYVQLI 62 >5O2P-A nrPDB Length = 100 Score = 32.7 bits (73), Expect = 0.19, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 4/58 (6%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEE---QWWSARNKDGRVGMIPVPYVEKLV 182 + LYD ++L F+KG+I+ ++E+ + WW + GR G++P ++ LV Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLC-SLHGRQGIVPGNRLKILV 66 Score = 31.6 bits (70), Expect = 0.43, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query: 238 VFAKAIQKRVPCAYDKTALALEVGDIVKVTRMN---INGQWEGEVNGRKGLFPFTHVKIF 294 V AKA+ V + D+ L+ GDI+ V + ++G W ++GR+G+ P +KI Sbjct: 8 VLAKALYDNVAESPDE--LSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKIL 65 >2DJQ-A nrPDB Length = 68 Score = 32.7 bits (73), Expect = 0.21, Method: Compositional matrix adjust. Identities = 14/52 (26%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 + L ++ G + DL F KG+++++ + +E W+ +G G+ P VE Sbjct: 10 AKALCNYRGKNPGDLKFNKGDVILLRRQLDENWYQGE-INGVSGIFPASSVE 60 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 22/39 (56%) Query: 256 LALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 L GD++ + R ++GE+NG G+FP + V++ Sbjct: 24 LKFNKGDVILLRRQLDENWYQGEINGVSGIFPASSVEVI 62 >2IZV-A nrPDB Length = 187 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 30/81 (37%), Positives = 38/81 (46%), Gaps = 8/81 (9%) Query: 15 YMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVS--ENSRVSHYIINSL-PNRRF 71 Y G + + A+ L+G+ G FL+RDS+ DY+ SVS SR H I N F Sbjct: 37 YWGVMDKYAAEALLEGKPEGTFLLRDSAQ--EDYLFSVSFRRYSRSLHARIEQWNHNFSF 94 Query: 72 KIGDQEFDHLP---ALLEFYK 89 D H P LLE YK Sbjct: 95 DAHDPCVFHSPDITGLLEHYK 115 >2RQW-A nrPDB Length = 105 Score = 32.3 bits (72), Expect = 0.27, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSAR--NKDGRVGMIPVPYV 178 Y LYDF A++L GE L I +W+ A+ + G G++PV +V Sbjct: 4 YAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFV 57 >5F3Y-A nrPDB Length = 621 Score = 32.3 bits (72), Expect = 0.28, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 5/43 (11%) Query: 137 NDAEDLPFKKGEILVIIEK----PEEQWWSARN-KDGRVGMIP 174 +D LPFKKG++L++ +K E W +N + G+ G++P Sbjct: 556 DDITLLPFKKGDLLILTKKQGLLASENWALGQNDRTGKTGLVP 598 >1M27-A nrPDB Length = 104 Score = 32.0 bits (71), Expect = 0.30, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 10 DRSAWYMGPVSRQEAQTRLQGQ-RHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 D A Y G +SR+ + L G +L+RDS + PG Y L V + + Y ++ Sbjct: 2 DAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVS 57 >5O2Q-A nrPDB Length = 99 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 4/57 (7%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEE---QWWSARNKDGRVGMIPVPYVEKLV 182 + LYD ++L F+KG+I+ ++E+ + WW + GR G++P ++ LV Sbjct: 11 KALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLC-SLHGRQGIVPGNRLKILV 66 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 5/60 (8%) Query: 238 VFAKAIQKRVPCAYDKTALALEVGDIVKVTRMN---INGQWEGEVNGRKGLFPFTHVKIF 294 V AKA+ V + D+ L+ GDI+ V + ++G W ++GR+G+ P +KI Sbjct: 8 VLAKALYDNVAESPDE--LSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKIL 65 >2KYM-A nrPDB Length = 120 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 2/54 (3%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSAR--NKDGRVGMIPVPYV 178 + TLY+F ++L GE L I + +W+ A+ N+ G G++PV YV Sbjct: 5 FAVTLYEFKAERDDELDVSPGENLSICAHYDYEWFIAKPINRLGGPGLVPVSYV 58 >1KA6-A nrPDB Length = 128 Score = 32.0 bits (71), Expect = 0.35, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 10 DRSAWYMGPVSRQEAQTRLQGQ-RHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 D A Y G +SR+ + L G +L+RDS + PG Y L V + + Y ++ Sbjct: 2 DAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVS 57 >2MIO-A nrPDB Length = 70 Score = 31.6 bits (70), Expect = 0.45, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Query: 248 PC-AYDKTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHVKIF 294 PC A + L+ E+G I + + + W EG +NG++GL P +VK+ Sbjct: 22 PCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL 70 Score = 28.9 bits (63), Expect = 3.1, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 25/53 (47%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 R +Y + +L F+ G I ++ E W +G+ G+IP YV+ L Sbjct: 18 RAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL 70 >1UGV-A nrPDB Length = 72 Score = 31.2 bits (69), Expect = 0.60, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 23/54 (42%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 + LY +L F G + + +E W +G+ G+IP YVE L Sbjct: 13 AKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL 66 >5JMQ-A nrPDB Length = 446 Score = 30.8 bits (68), Expect = 0.67, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 180 E+V + D+ D L F +GE ++I+ + WW + G G IP ++ K Sbjct: 47 EFV-AIADYTATDETQLSFLRGEKILILRQTTADWWWG-ERAGCCGYIPANHLGK 99 >1UHF-A nrPDB Length = 69 Score = 30.8 bits (68), Expect = 0.69, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 3/54 (5%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 EY+ LY + + DL F +GE +++ +K + +WW+ D R G+ P YV+ Sbjct: 10 EYI-ALYPYSSVEPGDLTFTEGEEILVTQK-DGEWWTGSIGD-RSGIFPSNYVK 60 >2EQI-A nrPDB Length = 69 Score = 30.8 bits (68), Expect = 0.78, Method: Compositional matrix adjust. Identities = 14/54 (25%), Positives = 24/54 (44%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 V+ LYD+ +++L F +G ++ + K WW P YVE + Sbjct: 10 VKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDI 63 >2DMO-A nrPDB Length = 68 Score = 30.8 bits (68), Expect = 0.85, Method: Compositional matrix adjust. Identities = 14/51 (27%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 R L+ F E+L G I+ +++K + W + +G+ G++P Y+E Sbjct: 11 RVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVM-FNGQKGLVPCNYLE 60 >4IIO-A nrPDB Length = 66 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 1/32 (3%) Query: 262 DIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 DI+ V N W GEV+G +G FP ++VKI Sbjct: 31 DIITVLEQQEN-WWFGEVHGGRGWFPKSYVKI 61 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 2/59 (3%) Query: 121 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 A+ L + L + L F K +I+ ++E+ +E WW GR G P YV+ Sbjct: 4 AQGALLKAQALCSWTAKKDNHLNFSKHDIITVLEQ-QENWWFGEVHGGR-GWFPKSYVK 60 >4WSI-A nrPDB Length = 394 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 29/52 (55%), Gaps = 7/52 (13%) Query: 119 PTAEDNLEYVRTLYDF-PGND------AEDLPFKKGEILVIIEKPEEQWWSA 163 P A++ + +V+ +D+ P +D L F+KG+IL +I + + WW A Sbjct: 110 PPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQA 161 >2GGS-A nrPDB Length = 273 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 24/43 (55%) Query: 26 TRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 +RL +RH + V +SS G Y L +++ R+ +II P+ Sbjct: 17 SRLLSERHEVIKVYNSSEIQGGYKLDLTDFPRLEDFIIKKRPD 59 >2CT4-A nrPDB Length = 70 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPE-EQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 +Y F G+ + +GE L ++E+ + + W R K+G G +P Y+ V S P Sbjct: 13 IYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYLR--VTSGP 67 >2BBU-A nrPDB Length = 164 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 22/45 (48%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENS 56 S +Y V+ EA L + G FL+RDSS + LSV S Sbjct: 23 SGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQS 67 >1RM6-B nrPDB Length = 324 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 19/37 (51%) Query: 134 FPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRV 170 F + AE L +KGE+L IE P WSA R+ Sbjct: 191 FRESGAEHLTLEKGELLAAIEVPPTGAWSAAYSKVRI 227 >2HMH-A nrPDB Length = 152 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 22/45 (48%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENS 56 S +Y V+ EA L + G FL+RDSS + LSV S Sbjct: 34 SGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQS 78 >6C5X-D nrPDB Length = 164 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 22/43 (51%) Query: 10 DRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSV 52 D +Y GP+ A +L+ + G FL+RDS + +SV Sbjct: 28 DTCGFYWGPMDVNVAHDKLKSEPIGTFLIRDSKQKNCFFAISV 70 >2CUC-A nrPDB Length = 70 Score = 28.5 bits (62), Expect = 3.3, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 26/49 (53%), Gaps = 1/49 (2%) Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPVPYV 178 L+ + + E+L +KGE + ++ K ++ W + GR G+ P YV Sbjct: 13 LHTYSAHRPEELDLQKGEGIRVLGKYQDGWLKGLSLLTGRTGIFPSDYV 61 >1XA6-A nrPDB Length = 466 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 17/71 (23%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 15 YMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIG 74 + G +SR++A L G G +++R+S PG Y L++ ++ +Y + + + +G Sbjct: 58 FHGIISREQADELLGGVE-GAYILRESQRQPGCYTLALRFGNQTLNYRL--FHDGKHFVG 114 Query: 75 DQEFDHLPALL 85 ++ F+ + L+ Sbjct: 115 EKRFESIHDLV 125 >2CUD-A nrPDB Length = 79 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 118 LPTAED-NLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPV 175 LP E + +++ L D+P D F++GE L +I E WW A + GR IP Sbjct: 9 LPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISD-EGGWWKAISLSTGRESYIPG 67 Query: 176 PYVEKL 181 V ++ Sbjct: 68 ICVARV 73 >1J3T-A nrPDB Length = 74 Score = 28.5 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 15/32 (46%), Positives = 20/32 (62%), Gaps = 1/32 (3%) Query: 262 DIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 DI+ V N W GEV+G +G FP ++VKI Sbjct: 33 DIITVLEQQEN-WWFGEVHGGRGWFPKSYVKI 63 Score = 27.3 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 3/47 (6%) Query: 142 LPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHG 188 L F K +I+ ++E+ +E WW GR G P YV K++ S G Sbjct: 27 LNFSKHDIITVLEQ-QENWWFGEVHGGR-GWFPKSYV-KIIPGSESG 70 >4GL9-E nrPDB Length = 143 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 22/45 (48%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENS 56 S +Y V+ EA L + G FL+RDSS + LSV S Sbjct: 28 SGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQS 72 >6AT4-A nrPDB Length = 546 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 32/162 (19%), Positives = 54/162 (33%), Gaps = 37/162 (22%) Query: 174 PVPYVEKLVRSSPHGKHGNR----NSNSYGIPEPAHAYAQPQT----------------- 212 P+ +++ +V+ H + ++++G+ P QT Sbjct: 337 PIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTER 396 Query: 213 --TTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKR------VPCAYDKTALALEVGDIV 264 T P P S GAA L TQ V K +Q V ++ T + + D Sbjct: 397 GITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTR 456 Query: 265 KVTRMNINGQWEGEVNGRKGLF--------PFTHVKIFDPQN 298 + +NG + +F P KI DP+N Sbjct: 457 AIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRN 498 >3ORG-A nrPDB Length = 632 Score = 27.7 bits (60), Expect = 6.5, Method: Compositional matrix adjust. Identities = 12/45 (26%), Positives = 22/45 (48%) Query: 178 VEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGS 222 +E LV +P G+H ++ + + EP + P +P+ S S Sbjct: 541 IEGLVDETPSGEHSSKGKRTATVLEPTSSLVVPCDVSPIVVTSYS 585 >1BB9-A nrPDB Length = 115 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVII--EKPEEQ 159 V+ +D+ D ++L K G+++++I + PEEQ Sbjct: 47 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQ 80 >1MV3-A nrPDB Length = 213 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 11/34 (32%), Positives = 22/34 (64%), Gaps = 2/34 (5%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVII--EKPEEQ 159 V+ +D+ D ++L K G+++++I + PEEQ Sbjct: 145 VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQ 178 >3CXL-A nrPDB Length = 463 Score = 27.3 bits (59), Expect = 9.0, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 15 YMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIG 74 + G +SR EA +L G +L+R+S PG Y L++ S+ ++ + + F +G Sbjct: 54 FHGMISR-EAADQLLIVAEGSYLIRESQRQPGTYTLALRFGSQTRNFRL-YYDGKHF-VG 110 Query: 75 DQEFDHLPALL 85 ++ F+ + L+ Sbjct: 111 EKRFESIHDLV 121 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2LQW-A nrPDB 439 e-124 2EYZ-A nrPDB 337 5e-93 3QWY-A nrPDB 257 4e-69 1GRI-A nrPDB 184 4e-47 4FL3-A nrPDB 142 2e-34 4XEY-B nrPDB 138 3e-33 1A81-A nrPDB 135 2e-32 2FO0-A nrPDB 135 3e-32 2XKX-A nrPDB 134 5e-32 6AMW-A nrPDB 127 5e-30 3T04-A nrPDB 125 3e-29 2ABL-A nrPDB 117 8e-27 1K9A-A nrPDB 110 1e-24 2LCT-A nrPDB 109 1e-24 4XZ1-A nrPDB 109 2e-24 2OZO-A nrPDB 108 2e-24 2KBT-A nrPDB 108 4e-24 2CRH-A nrPDB 106 2e-23 6F3F-A nrPDB 106 2e-23 2AUG-A nrPDB 104 4e-23 2H8H-A nrPDB 104 6e-23 1AD5-A nrPDB 103 9e-23 5U06-A nrPDB 99 1e-21 6CMQ-A nrPDB 99 2e-21 4H1O-A nrPDB 99 2e-21 2KK6-A nrPDB 99 3e-21 4XI2-A nrPDB 97 9e-21 2CS0-A nrPDB 96 1e-20 1NRV-A nrPDB 96 2e-20 2HDV-A nrPDB 94 5e-20 1MIL-A nrPDB 93 1e-19 2B3O-A nrPDB 93 2e-19 3PS5-A nrPDB 91 4e-19 3GF9-A nrPDB 88 4e-18 5M6U-B nrPDB 87 1e-17 3JV3-A nrPDB 86 2e-17 5VEI-A nrPDB 86 2e-17 2V1R-A nrPDB 86 2e-17 1GCQ-A nrPDB 86 2e-17 1N5Z-A nrPDB 86 2e-17 4BNE-A nrPDB 85 3e-17 4JGH-A nrPDB 84 5e-17 2YUP-A nrPDB 84 6e-17 6F55-A nrPDB 84 7e-17 4N78-F nrPDB 83 1e-16 3HAJ-A nrPDB 83 2e-16 2ED1-A nrPDB 82 3e-16 2X3W-D nrPDB 81 6e-16 2ED0-A nrPDB 79 2e-15 2YDL-A nrPDB 78 7e-15 2K6D-A nrPDB 78 7e-15 1NM7-A nrPDB 77 1e-14 2K9G-A nrPDB 77 1e-14 2RQT-A nrPDB 76 1e-14 1K4U-S nrPDB 68 7e-12 Sequences not found previously or not previously below threshold: 1RPY-A nrPDB 84 5e-17 4M4Z-A nrPDB 82 2e-16 2PLE-A nrPDB 78 4e-15 2EOB-A nrPDB 76 2e-14 4E93-A nrPDB 74 5e-14 3EHQ-A nrPDB 74 1e-13 2EKX-A nrPDB 72 3e-13 2DA9-A nrPDB 71 5e-13 3CXL-A nrPDB 71 6e-13 1XA6-A nrPDB 70 1e-12 1GBQ-A nrPDB 70 1e-12 2PZ1-A nrPDB 68 4e-12 6C5X-D nrPDB 68 6e-12 6C7Y-B nrPDB 68 8e-12 2VIF-A nrPDB 67 8e-12 2NWM-A nrPDB 67 1e-11 2DYB-A nrPDB 66 1e-11 2DLM-A nrPDB 65 3e-11 5NXJ-A nrPDB 64 6e-11 3ULR-B nrPDB 64 6e-11 4MT6-A nrPDB 63 1e-10 4GL9-E nrPDB 63 1e-10 2BBU-A nrPDB 63 2e-10 2EQI-A nrPDB 63 2e-10 1X69-A nrPDB 62 2e-10 2O2O-A nrPDB 62 2e-10 5XHZ-A nrPDB 62 3e-10 1Z9Q-A nrPDB 62 3e-10 1WI7-A nrPDB 62 3e-10 2HMH-A nrPDB 62 3e-10 1M27-A nrPDB 62 3e-10 1KA6-A nrPDB 62 3e-10 2HSP-A nrPDB 62 4e-10 1YWO-A nrPDB 62 4e-10 1W6X-A nrPDB 61 9e-10 1UEC-A nrPDB 59 2e-09 1OV3-A nrPDB 59 2e-09 2DJQ-A nrPDB 57 9e-09 5O2M-A nrPDB 57 1e-08 5JMQ-A nrPDB 57 1e-08 2IZV-A nrPDB 57 1e-08 5O2Q-A nrPDB 56 2e-08 5O2P-A nrPDB 56 2e-08 5NP2-A nrPDB 56 3e-08 4WSI-A nrPDB 55 3e-08 2M0Y-A nrPDB 54 8e-08 2V1Q-A nrPDB 52 2e-07 1I07-A nrPDB 52 2e-07 1WXU-A nrPDB 52 2e-07 2CUC-A nrPDB 52 2e-07 1UHF-A nrPDB 52 3e-07 1UGV-A nrPDB 52 4e-07 4IIO-A nrPDB 51 5e-07 2MIO-A nrPDB 51 6e-07 2JT4-A nrPDB 51 6e-07 1UE9-A nrPDB 51 8e-07 1UUS-A nrPDB 50 1e-06 2VKN-A nrPDB 49 2e-06 1J3T-A nrPDB 49 2e-06 2ENM-A nrPDB 49 3e-06 3PJP-A nrPDB 47 9e-06 2DMO-A nrPDB 47 1e-05 2KYM-A nrPDB 45 4e-05 5VKO-A nrPDB 45 4e-05 1BB9-A nrPDB 45 5e-05 3A98-A nrPDB 44 7e-05 1MV3-A nrPDB 44 1e-04 1VYT-A nrPDB 43 2e-04 1MV0-B nrPDB 43 2e-04 2EL8-A nrPDB 43 2e-04 4DEX-A nrPDB 42 3e-04 2RQR-A nrPDB 41 5e-04 2RQW-A nrPDB 41 7e-04 3GXW-A nrPDB 41 8e-04 2CT4-A nrPDB 40 0.001 2CR4-A nrPDB 40 0.001 2GTJ-A nrPDB 39 0.002 1VYV-A nrPDB 39 0.002 1SPK-A nrPDB 39 0.002 1GCP-A nrPDB 39 0.002 1Y1U-A nrPDB 39 0.003 3RNJ-A nrPDB 38 0.004 1K1Z-A nrPDB 38 0.004 2KXC-A nrPDB 38 0.004 4ZW2-A nrPDB 38 0.005 3MAZ-A nrPDB 37 0.011 4Y5W-A nrPDB 37 0.013 1T0J-A nrPDB 37 0.013 1U3O-A nrPDB 36 0.027 2DE0-X nrPDB 36 0.027 2CUD-A nrPDB 36 0.027 5F3Y-A nrPDB 36 0.028 4HZS-A nrPDB 35 0.039 5GJW-B nrPDB 34 0.072 3TSW-A nrPDB 34 0.11 3LH5-A nrPDB 33 0.18 3SHW-A nrPDB 32 0.24 4E68-A nrPDB 32 0.32 1E5Q-A nrPDB 32 0.35 1BF5-A nrPDB 31 0.47 3HZG-A nrPDB 31 0.56 6GME-A nrPDB 31 0.79 1YVL-A nrPDB 30 1.3 2DIA-A nrPDB 30 1.4 6DLH-A nrPDB 30 1.4 6DNS-A nrPDB 30 1.4 4FK8-A nrPDB 30 1.6 1J9A-A nrPDB 29 1.8 5JU6-A nrPDB 29 2.4 2AAN-A nrPDB 27 8.6 >2LQW-A nrPDB Length = 303 Score = 439 bits (1130), Expect = e-124, Method: Composition-based stats. Identities = 303/303 (100%), Positives = 303/303 (100%) Query: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH Sbjct: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 Query: 61 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT 120 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT Sbjct: 61 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT 120 Query: 121 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 180 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK Sbjct: 121 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 180 Query: 181 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA 240 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA Sbjct: 181 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA 240 Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD Sbjct: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 Query: 301 ENE 303 ENE Sbjct: 301 ENE 303 >2EYZ-A nrPDB Length = 304 Score = 337 bits (863), Expect = 5e-93, Method: Composition-based stats. Identities = 181/323 (56%), Positives = 216/323 (66%), Gaps = 45/323 (13%) Query: 3 SARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYI 62 + FDS +RS+WY G +SRQEA LQGQRHG+FLVRDSST PGDYVLSVSENSRVSHYI Sbjct: 2 AGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYI 61 Query: 63 IN-----------------SLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRY 105 IN + R +IGDQEFD LPALLEFYKIHYLDTTTLIEP R Sbjct: 62 INSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSR- 120 Query: 106 PSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN 165 S + ++ EYVR L+DF GND EDLPFKKG+IL I +KPEEQWW+A + Sbjct: 121 ------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAED 174 Query: 166 KDGRVGMIPVPYVEKL------VRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAV 219 +G+ GMIPVPYVEK V + G + G PEP YAQP TPLP + Sbjct: 175 SEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPG-PYAQPSVNTPLPNL 233 Query: 220 SGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEV 279 QNGP++A+ IQKRVP AYDKTALALEVG++VKVT++N++GQWEGE Sbjct: 234 --------------QNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEGEC 279 Query: 280 NGRKGLFPFTHVKIFDPQNPDEN 302 NG++G FPFTHV++ D QNP+E+ Sbjct: 280 NGKRGHFPFTHVRLLDQQNPEED 302 >3QWY-A nrPDB Length = 308 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 90/305 (29%), Positives = 135/305 (44%), Gaps = 43/305 (14%) Query: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQ--RHGMFLVRDSSTCPGDYVLSVSE---N 55 M++ FD + ++Y +SR+EA L G FL+RDSS PG+Y L+V E Sbjct: 30 MTTNGFDPFEWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDSSR-PGEYSLTVREADEG 88 Query: 56 SRVSHYIINS-------LPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSP 108 + V HY+I KI +Q F +PALL +K+ L +L+ Y P Sbjct: 89 NAVCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTEASLLAA---YKKP 145 Query: 109 PMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDG 168 +E V + F G DLPF++GE L I+ K + WW ARN G Sbjct: 146 I---------------IEVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNALG 190 Query: 169 RVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAIT 228 G++P YV+ + H +R S + + + A + S + Sbjct: 191 TTGLVPANYVQIQMEF-----HNDRTSKGASQSSIGSSGGGAERFS--SASTSSDNIELQ 243 Query: 229 PLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPF 288 P P AK RVP AYD T L ++ G V VT+ NG ++ E++G+ G P Sbjct: 244 P-----RLPAKAKVTFDRVPNAYDPTQLRVKKGQTVLVTQKMSNGMYKAELDGQIGSVPH 298 Query: 289 THVKI 293 T+++ Sbjct: 299 TYLRF 303 >1GRI-A nrPDB Length = 217 Score = 184 bits (467), Expect = 4e-47, Method: Composition-based stats. Identities = 45/174 (25%), Positives = 85/174 (48%), Gaps = 16/174 (9%) Query: 12 SAWYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRR 70 W+ G + R +A+ L QR G FL+R+S + PGD+ LSV + V H+ + + Sbjct: 58 HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGK 117 Query: 71 FKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRT 130 + + +F+ L L+++++ +T + + + V P PT YV+ Sbjct: 118 YFLWVVKFNSLNELVDYHR------STSVSRNQQIFLRDIEQV--PQQPT------YVQA 163 Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 L+DF + +L F++G+ + +++ + WW G+ GM P YV + R+ Sbjct: 164 LFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH-GQTGMFPRNYVTPVNRN 216 Score = 91.4 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 38/211 (18%), Positives = 67/211 (31%), Gaps = 50/211 (23%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKP-EEQWWSARNKDGRVGMIPVPYVE------- 179 YDF ++L FK+G+IL ++ + ++ W+ A +G+ G IP Y+E Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAE-LNGKDGFIPKNYIEMKPHPWF 61 Query: 180 -------KLVRSSPHGKHGN------RNSNSYGIPEPAHAYAQPQTTTPL---------- 216 K +H S Q L Sbjct: 62 FGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLW 121 Query: 217 ----------------PAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEV 260 +VS + + + P + +A+ P + L Sbjct: 122 VVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDP--QEDGELGFRR 179 Query: 261 GDIVKVTRMNINGQWEGEVNGRKGLFPFTHV 291 GD + V + W+G +G+ G+FP +V Sbjct: 180 GDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 210 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNIN-GQWEGEVNGRKGLFPFTHVKIFD 295 +AI K A L+ + GDI+KV + ++ E+NG+ G P ++++ Sbjct: 2 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKP 57 >4FL3-A nrPDB Length = 635 Score = 142 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 5/144 (3%) Query: 2 SSARFDSSDRSAWYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVS 59 SS DS++ ++ G ++R+EA+ L G G++L+R S G + LSV+ + Sbjct: 3 SSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAH 62 Query: 60 HYIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLP 119 HY I N + I PA L Y D + P + P Sbjct: 63 HYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKP-FNRPQGVQPKTGPFE 121 Query: 120 TAEDNL--EYVRTLYDFPGNDAED 141 ++NL EYV+ ++ G E Sbjct: 122 DLKENLIREYVKQTWNLQGQALEQ 145 Score = 89.5 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 5/118 (4%) Query: 8 SSDRSAWYMGPVSRQEAQT--RLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + ++ W+ G +SR+E++ + + +G FL+R G Y L + +V HY I+ Sbjct: 162 AHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDK 220 Query: 66 LPNRRFKI-GDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAE 122 + I ++FD L L+E Y + D + P G+V+ P Sbjct: 221 DKTGKLSIPEGKKFDTLWQLVEHY-SYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLP 277 >4XEY-B nrPDB Length = 408 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 43/130 (33%), Positives = 63/130 (48%), Gaps = 9/130 (6%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYII 63 A +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY I Sbjct: 2 ASVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRI 61 Query: 64 NSLPNRRFKIGDQ-EFDHLPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVSAPNLPT 120 N+ + + + + F+ L L+ + D TTL PAP+ P + VS Sbjct: 62 NTASDGKLYVSSESRFNTLAELV-HHHSTVADGLITTLHYPAPKRNKPTVYGVS-----P 115 Query: 121 AEDNLEYVRT 130 D E RT Sbjct: 116 NYDKWEMERT 125 >1A81-A nrPDB Length = 254 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 39/198 (19%), Positives = 73/198 (36%), Gaps = 15/198 (7%) Query: 8 SSDRSAWYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 S++ ++ G ++R+EA+ L G G++L+R S G + LSV+ + HY I Sbjct: 1 SANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIER 60 Query: 66 LPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNL 125 N + I PA L Y D + P + P ++NL Sbjct: 61 ELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKP-FNRPQGVQPKTGPFEDLKENL 119 Query: 126 --EYVRTLYDFPGNDAEDLPFKKGEILVII----EKPEEQWWSA---RNKDGRVGMIPVP 176 EYV+ ++ G E + L + + W+ R + ++ +I Sbjct: 120 IREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQIVLIGS- 178 Query: 177 YVEKLVRSSPHGKHGNRN 194 + + + N + Sbjct: 179 --KTNGKFLIRARDNNGS 194 Score = 88.3 bits (217), Expect = 4e-18, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 4/84 (4%) Query: 8 SSDRSAWYMGPVSRQEAQT--RLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + ++ W+ G +SR+E++ + + +G FL+R G Y L + +V HY I+ Sbjct: 154 AHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNN-GSYALCLLHEGKVLHYRIDK 212 Query: 66 LPNRRFKI-GDQEFDHLPALLEFY 88 + I ++FD L L+E Y Sbjct: 213 DKTGKLSIPEGKKFDTLWQLVEHY 236 >2FO0-A nrPDB Length = 495 Score = 135 bits (339), Expect = 3e-32, Method: Composition-based stats. Identities = 42/128 (32%), Positives = 62/128 (48%), Gaps = 9/128 (7%) Query: 6 FDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 96 VNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 155 Query: 66 LPNRRFKIGDQ-EFDHLPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVSAPNLPTAE 122 + + + + F+ L L+ + D TTL PAP+ P + VS Sbjct: 156 ASDGKLYVSSESRFNTLAELV-HHHSTVADGLITTLHYPAPKRNKPTVYGVS-----PNY 209 Query: 123 DNLEYVRT 130 D E RT Sbjct: 210 DKWEMERT 217 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 2/109 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIE-KPEEQWWSARNKDGRVGMIPVPYV 178 +E++ LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ Sbjct: 35 PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYI 93 Query: 179 EKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAI 227 + H + S + + + G ++ Sbjct: 94 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISL 142 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 32/89 (35%), Gaps = 6/89 (6%) Query: 204 AHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDI 263 +PQ + + P ++N P + A L++ G+ Sbjct: 10 GDQRREPQGLSEAARWNSKENLLAGP---SENDPNL--FVALYDFVASGDNTLSITKGEK 64 Query: 264 VKVTRMNINGQW-EGEVNGRKGLFPFTHV 291 ++V N NG+W E + +G P ++ Sbjct: 65 LRVLGYNHNGEWCEAQTKNGQGWVPSNYI 93 >2XKX-A nrPDB Length = 721 Score = 134 bits (337), Expect = 5e-32, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 61/149 (40%), Gaps = 14/149 (9%) Query: 112 SVSAPNLPTAEDNLEYVRTLYDFP-----GNDAEDLPFKKGEILVIIEKPEEQWWSAR-- 164 +L + Y+R L+D+ G ++ L F+ G++L +I+ +E+WW AR Sbjct: 414 GSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRV 473 Query: 165 ---NKDGRVGMIPVPY-VEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVS 220 ++ +G IP VE+ S K +S S G + +Y +T T + Sbjct: 474 HSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSY---ETVTQMEVHY 530 Query: 221 GSPGAAITPLPSTQNGPVFAKAIQKRVPC 249 P + P N + ++ K C Sbjct: 531 ARPIIILGPTKDRANDDLLSEFPDKFGSC 559 >6AMW-A nrPDB Length = 255 Score = 127 bits (319), Expect = 5e-30, Method: Composition-based stats. Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 9/124 (7%) Query: 6 FDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 138 VNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 197 Query: 66 LPNRRFKIGDQ-EFDHLPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVSAPNLPTAE 122 + + + + F+ L L+ + D TTL PAP+ P + VS Sbjct: 198 ASDGKLYVSSESRFNTLAELV-HHHSTVADGLITTLHYPAPKRNKPTVYGVS-----PNY 251 Query: 123 DNLE 126 D E Sbjct: 252 DKWE 255 Score = 51.7 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 2/109 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIE-KPEEQWWSARNKDGRVGMIPVPYV 178 +E++ LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ Sbjct: 77 PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWAEAQTKNGQ-GWVPSNYI 135 Query: 179 EKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAI 227 + H + S + + + G ++ Sbjct: 136 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISL 184 Score = 40.9 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 6/113 (5%) Query: 180 KLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVF 239 K S G H N + P + +PQ + + P ++N P Sbjct: 28 KRESSRHGGPHCNVFVEHEALQRPVASDFEPQGLSEAARWNSKENLLAGP---SENDPNL 84 Query: 240 AKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHV 291 + A L++ G+ ++V N NG+W E + +G P ++ Sbjct: 85 --FVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWAEAQTKNGQGWVPSNYI 135 >3T04-A nrPDB Length = 123 Score = 125 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 4/112 (3%) Query: 6 FDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 10 VNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 69 Query: 66 LPNRRFKIGDQ-EFDHLPALLEFYKIHYLDT--TTLIEPAPRYPSPPMGSVS 114 + + + + F+ L L+ + D TTL PAP+ P + VS Sbjct: 70 ASDGKLYVSSESRFNTLAELV-HHHSTVADGLITTLHYPAPKRNKPTVYGVS 120 >2ABL-A nrPDB Length = 163 Score = 117 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 35/101 (34%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Query: 6 FDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 +S ++ +WY GPVSR A+ L +G FLVR+S + PG +S+ RV HY IN+ Sbjct: 64 VNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINT 123 Query: 66 LPNRRFKIGDQ-EFDHLPALLEFYKIHYLDT--TTLIEPAP 103 + + + + F+ L L+ + D TTL PAP Sbjct: 124 ASDGKLYVSSESRFNTLAELV-HHHSTVADGLITTLHYPAP 163 Score = 55.6 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 39/109 (35%), Gaps = 2/109 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIE-KPEEQWWSARNKDGRVGMIPVPYV 178 +E++ LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ Sbjct: 3 PSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYI 61 Query: 179 EKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAI 227 + H + S + + + G ++ Sbjct: 62 TPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISL 110 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 26/60 (43%), Gaps = 3/60 (5%) Query: 233 TQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHV 291 ++N P + A L++ G+ ++V N NG+W E + +G P ++ Sbjct: 4 SENDPNL--FVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYI 61 >1K9A-A nrPDB Length = 450 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 27/77 (35%), Positives = 43/77 (55%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRF 71 W+ G ++R++A+ L G+FLVR+S+ PGDY L VS +V HY I ++ Sbjct: 80 MPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLS 139 Query: 72 KIGDQEFDHLPALLEFY 88 + F++L L+E Y Sbjct: 140 IDEEVYFENLMQLVEHY 156 Score = 76.7 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 24/61 (39%), Positives = 34/61 (55%), Gaps = 1/61 (1%) Query: 130 TLYDFPGNDAEDLPFKKGEILVIIEKP-EEQWWSARNKDGRVGMIPVPYVEKLVRSSPHG 188 Y+F G +DLPF KG++L I+ + W+ A+NK GR G+IP YV+K Sbjct: 16 AKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGT 75 Query: 189 K 189 K Sbjct: 76 K 76 >2LCT-A nrPDB Length = 107 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 43/104 (41%), Gaps = 1/104 (0%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYII 63 WY GP+ R A++ L + G FLVR ++ +S+ N V H I Sbjct: 1 GHMQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI 60 Query: 64 NSLPNRRFKIGDQEFDHLPALLEFYKIHYL-DTTTLIEPAPRYP 106 + + F L L+EFY+ + L D ++ ++P Sbjct: 61 MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 104 >4XZ1-A nrPDB Length = 262 Score = 109 bits (272), Expect = 2e-24, Method: Composition-based stats. Identities = 36/140 (25%), Positives = 53/140 (37%), Gaps = 7/140 (5%) Query: 7 DSSDRSAWYMGPVSRQEAQT--RLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 D + ++ G +SR EA+ +L G G+FL+R G YVLS+ + R H+ I Sbjct: 6 DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIE 65 Query: 65 SLPNRRFKIGDQEFDHLP-ALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAED 123 N + I + P L EFY D P P + D Sbjct: 66 RQLNGTYAIAGGKAHCGPAELCEFY-SRDPDGLPCNLRKPC-NRPSGLEPQPGVFDSLRD 123 Query: 124 NL--EYVRTLYDFPGNDAED 141 + +YVR + G E Sbjct: 124 AMVRDYVRQTWKLEGEALEQ 143 Score = 84.4 bits (207), Expect = 6e-17, Method: Composition-based stats. Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQG--QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + +R WY ++R+EA+ +L Q G FL+R G Y LS+ V HY+I+ Sbjct: 160 AHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPR-KEQGTYALSLIYGKTVYHYLISQ 218 Query: 66 LPNRRFKI-GDQEFDHLPALLEFYKI 90 ++ I +FD L L+E+ K+ Sbjct: 219 DKAGKYCIPEGTKFDTLWQLVEYLKL 244 >2OZO-A nrPDB Length = 613 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 7/140 (5%) Query: 7 DSSDRSAWYMGPVSRQEAQT--RLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 D + ++ G +SR EA+ +L G G+FL+R G YVLS+ + R H+ I Sbjct: 3 DPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIE 62 Query: 65 SLPNRRFKIGDQEFDHLP-ALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAED 123 N + I + P L EFY D P P D Sbjct: 63 RQLNGTYAIAGGKAHCGPAELCEFY-SRDPDGLPCNLRKPC-NRPSGLEPQPGVFDCLRD 120 Query: 124 NL--EYVRTLYDFPGNDAED 141 + +YVR + G E Sbjct: 121 AMVRDYVRQTWKLEGEALEQ 140 Score = 86.8 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 35/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQG--QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + +R WY ++R+EA+ +L Q G FL+R G Y LS+ V HY+I+ Sbjct: 157 AHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPR-KEQGTYALSLIYGKTVYHYLISQ 215 Query: 66 LPNRRFKI-GDQEFDHLPALLEFYKIHYLDTTTLI-EPAPRYPSPPMGSVSAPNLPTAED 123 ++ I +FD L L+E+ K+ + E P + +AP LP Sbjct: 216 DKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTLPAHPS 275 Query: 124 NLEYVRTLYD 133 L + + D Sbjct: 276 TLTHPQRRID 285 >2KBT-A nrPDB Length = 142 Score = 108 bits (269), Expect = 4e-24, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 1/95 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK-LVRSSP 186 + YDF D +L K+G+I+ I+ K +Q W GR+G P YVE+ P Sbjct: 8 AKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVEEDYSEYLP 67 Query: 187 HGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSG 221 G+ +S +Y + TT + A + Sbjct: 68 ETGGGSGSSMTYKLILNGKTLKGETTTEAVDAATA 102 Score = 78.7 bits (192), Expect = 3e-15, Method: Composition-based stats. Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 238 VFAKAIQKRVPCAYDKTALALEVGDIVKVTRMN-INGQWEGEVNGRKGLFPFTHVK 292 F A + CA D++ L+L+ GDI+K+ G W GE+ GR G FP +V+ Sbjct: 4 TFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRIGWFPSNYVE 59 >2CRH-A nrPDB Length = 138 Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 44/106 (41%), Gaps = 1/106 (0%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRF 71 WY GP+ R A++ L + G FLVR ++ +S+ N V H I + Sbjct: 26 HLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYR 85 Query: 72 KIGDQEFDHLPALLEFYKIHYL-DTTTLIEPAPRYPSPPMGSVSAP 116 + F L L+EFY+ + L D ++ ++P + Sbjct: 86 ITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTIS 131 >6F3F-A nrPDB Length = 455 Score = 106 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 13/111 (11%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRH--GMFLVRDSSTCPGDYVLSVSE-----NSRVS 59 DS WY G ++R+E++ L + G FLVR+S T G Y LSVS+ V Sbjct: 63 DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 122 Query: 60 HYIINSLPNRRFKIGD-QEFDHLPALLEFYKIH-----YLDTTTLIEPAPR 104 HY I L + F I +F+ L L+ +Y H + TT P+ Sbjct: 123 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQ 173 Score = 75.6 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPVPYVEK 180 LYD+ DL FKKGE L I+ E WW A + G+ G IP YV Sbjct: 9 VALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAP 61 Score = 35.5 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 10/66 (15%), Positives = 23/66 (34%), Gaps = 2/66 (3%) Query: 238 VFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGE--VNGRKGLFPFTHVKIFD 295 + + + +T L+ + G+ +++ W G+ G P +V D Sbjct: 4 MVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSD 63 Query: 296 PQNPDE 301 +E Sbjct: 64 SIQAEE 69 >2AUG-A nrPDB Length = 126 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 7/90 (7%) Query: 9 SDRSAWYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSL 66 W+ +SR EAQ + QG G+FLVRDS + P +VLS+S ++ H+ I + Sbjct: 23 HRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIPV 82 Query: 67 PN-----RRFKIGDQEFDHLPALLEFYKIH 91 + G F L L+EFY+++ Sbjct: 83 EDDGEMFHTLDDGHTRFTDLIQLVEFYQLN 112 >2H8H-A nrPDB Length = 535 Score = 104 bits (258), Expect = 6e-23, Method: Composition-based stats. Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 13/111 (11%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQGQRH--GMFLVRDSSTCPGDYVLSVSE-----NSRVS 59 DS WY G ++R+E++ L + G FLVR+S T G Y LSVS+ V Sbjct: 143 DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVK 202 Query: 60 HYIINSLPNRRFKIGD-QEFDHLPALLEFYKIH-----YLDTTTLIEPAPR 104 HY I L + F I +F+ L L+ +Y H + TT P+ Sbjct: 203 HYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQ 253 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 2/77 (2%) Query: 105 YPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSAR 164 + S + P A +V LYD+ DL FKKGE L I+ E WW A Sbjct: 66 FNSSDTVTSPQRAGPLAGGVTTFV-ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAH 124 Query: 165 N-KDGRVGMIPVPYVEK 180 + G+ G IP YV Sbjct: 125 SLSTGQTGYIPSNYVAP 141 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 41/126 (32%), Gaps = 11/126 (8%) Query: 187 HGKHGNR--NSNSYGIPEPAHAYAQPQTTTPL----PAVSGSPGAAITPLPSTQNGPVFA 240 HG G S + P A + P P + G ++ T + GP+ Sbjct: 24 HGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAG 83 Query: 241 ---KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGE--VNGRKGLFPFTHVKIFD 295 + + +T L+ + G+ +++ W G+ G P +V D Sbjct: 84 GVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSD 143 Query: 296 PQNPDE 301 +E Sbjct: 144 SIQAEE 149 >1AD5-A nrPDB Length = 438 Score = 103 bits (257), Expect = 9e-23, Method: Composition-based stats. Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 8/94 (8%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQ--GQRHGMFLVRDSSTCPGDYVLSV-----SENS 56 AR DS + W+ +SR++A+ +L G G F++RDS T G Y LSV + Sbjct: 56 ARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGD 115 Query: 57 RVSHYIINSLPNRRFKIGDQE-FDHLPALLEFYK 89 V HY I +L N F I + F L L++ YK Sbjct: 116 TVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYK 149 Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 2/55 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRV-GMIPVPYVEKL 181 V LYD+ EDL F+KG+ +V++E+ E WW AR+ R G IP YV ++ Sbjct: 5 VVALYDYEAIHHEDLSFQKGDQMVVLEESGE-WWKARSLATRKEGYIPSNYVARV 58 >5U06-A nrPDB Length = 120 Score = 99.5 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 30/85 (35%), Positives = 46/85 (54%), Gaps = 7/85 (8%) Query: 14 WYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN-SLPNRR 70 W+ G +SR+E+Q + QG G+FLVR+S P +VLS+ +V HY+I S R Sbjct: 19 WFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGR 78 Query: 71 FKI----GDQEFDHLPALLEFYKIH 91 G F L L+EF++++ Sbjct: 79 LYFSMDDGQTRFTDLLQLVEFHQLN 103 >6CMQ-A nrPDB Length = 427 Score = 99.1 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 11/89 (12%) Query: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSEN----------SRVSHYI 62 W+ G +S +EA+ L + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 10 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 69 Query: 63 INSLPNRRFKIGDQEFDHLPALLEFYKIH 91 I + G + FD L L+E YK + Sbjct: 70 IRCQELKYDVGGGERFDSLTDLVEHYKKN 98 >4H1O-A nrPDB Length = 560 Score = 99.1 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 11/89 (12%) Query: 14 WYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSEN----------SRVSHYI 62 W+ G +S +EA+ L + +HG FLVR+S + PGD+VLSV S+V+H + Sbjct: 133 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 192 Query: 63 INSLPNRRFKIGDQEFDHLPALLEFYKIH 91 I + G + FD L L+E YK + Sbjct: 193 IRCQELKYDVGGGERFDSLTDLVEHYKKN 221 Score = 89.1 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Query: 6 FDSSDRSAWYMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 F W+ ++ EA+ L G FL R S + PGD+ LSV N V+H I Sbjct: 19 FQGMTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQ 78 Query: 65 SLPNRRFKIGDQEFDHLPALLEFYKIHY 92 + G ++F L L+++Y H+ Sbjct: 79 NTGGYYDLYGGEKFATLAELVQYYMEHH 106 >2KK6-A nrPDB Length = 116 Score = 98.7 bits (244), Expect = 3e-21, Method: Composition-based stats. Identities = 33/105 (31%), Positives = 50/105 (47%), Gaps = 8/105 (7%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLP 67 WY G + R EAQ L+ Q G FLVR+S PG+YVLSV + + H+II + Sbjct: 13 PLAEQDWYHGAIPRIEAQELLKKQ--GDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVD 70 Query: 68 NRRFKIGDQEFDHLPALLEFY-----KIHYLDTTTLIEPAPRYPS 107 N ++ F ++P L++ + I L+ P P+ Sbjct: 71 N-MYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPKDKK 114 >4XI2-A nrPDB Length = 446 Score = 97.2 bits (240), Expect = 9e-21, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 60/136 (44%), Gaps = 12/136 (8%) Query: 7 DSSDRSAWYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSENSR------VS 59 DS + WY ++R +A+ L Q + G F+VRDSS G Y +SV S + Sbjct: 61 DSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSK-AGKYTVSVFAKSTGEPQGVIR 119 Query: 60 HYIINSLPNRRFKIGDQE-FDHLPALLEFYKIHY---LDTTTLIEPAPRYPSPPMGSVSA 115 HY++ S P ++ + ++ F +P L+ +++ + + +P + Sbjct: 120 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAGLISRLKYPVSKQNKNAPSTAGLGY 179 Query: 116 PNLPTAEDNLEYVRTL 131 + +L +++ L Sbjct: 180 GSWEIDPKDLTFLKEL 195 Score = 84.1 bits (206), Expect = 6e-17, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 38/88 (43%), Gaps = 1/88 (1%) Query: 124 NLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVR 183 L+ V LYD+ +A DL +KGE I+E+ WW AR+K+G+ G IP Y+ + Sbjct: 2 ELKKVVALYDYMPMNANDLQLRKGEEYFILEESNLPWWRARDKNGQEGYIPSNYITEAED 61 Query: 184 SSPHGKHGNRNSNSYGIPEPAHAYAQPQ 211 S + E + Sbjct: 62 S-IEMYEWYSKHMTRSQAEQLLKQEGKE 88 >2CS0-A nrPDB Length = 119 Score = 96.4 bits (238), Expect = 1e-20, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 3/104 (2%) Query: 13 AWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 W+ G +SR++A+ L+ Q G FL+R S + G Y LS S H+++ L + F Sbjct: 17 EWFHGAISREDAENLLESQPLGSFLIRVSHSHVG-YTLSYKAQSSCCHFMVKLLDDGTFM 75 Query: 73 IGDQEF--DHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVS 114 I ++ L AL+ F++ ++ + P S Sbjct: 76 IPGEKVAHTSLDALVTFHQQKPIEPRRELLTQPCRQKDSGPSSG 119 >1NRV-A nrPDB Length = 105 Score = 95.6 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Query: 9 SDRSAWYMGPVSRQEAQTRL--QGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN-S 65 W+ G +SR+E+ + QG G+FL+RDS + P +VL++ + ++ ++ I Sbjct: 2 HRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPC 61 Query: 66 LPNRRFKI----GDQEFDHLPALLEFYKIH 91 + + G+ +F L L++FY+++ Sbjct: 62 EDDGQTFFSLDDGNTKFSDLIQLVDFYQLN 91 >2HDV-A nrPDB Length = 111 Score = 94.5 bits (233), Expect = 5e-20, Method: Composition-based stats. Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 3/91 (3%) Query: 4 ARFDSSDRSAWYMGPVSR-QEAQTRLQGQ--RHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 W+ G +SR + AQ L+G HG+FLVR S T G+ VL+ + + H Sbjct: 1 GSDQPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTFNFQGKAKH 60 Query: 61 YIINSLPNRRFKIGDQEFDHLPALLEFYKIH 91 ++ + ++ F + +LE +++H Sbjct: 61 LRLSLNAAGQCRVQHLHFQSIFDMLEHFRVH 91 >1MIL-A nrPDB Length = 104 Score = 93.3 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 26/82 (31%), Positives = 47/82 (57%), Gaps = 3/82 (3%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRF 71 W+ G +SR+EA+ LQ +G FLVR+S+T PG YVL+ ++ + H ++ P Sbjct: 7 EPWFHGKLSRREAEALLQ--LNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLV-DPEGVV 63 Query: 72 KIGDQEFDHLPALLEFYKIHYL 93 + D F+ + L+ ++ ++L Sbjct: 64 RTKDHRFESVSHLISYHMDNHL 85 >2B3O-A nrPDB Length = 532 Score = 92.5 bits (228), Expect = 2e-19, Method: Composition-based stats. Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 13/123 (10%) Query: 14 WYMGPVSRQEAQTRLQGQRH-GMFLVRDSSTCPGDYVLSVSENS---------RVSHYII 63 WY G +S +A+T LQ + FLVR+S + PGD+VLSV + RV+H + Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKV 169 Query: 64 NSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAED 123 R G + FD L L+E +K ++ + A Y P + Sbjct: 170 MCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASG---AFVYLRQPYYATRVNAADIENR 226 Query: 124 NLE 126 LE Sbjct: 227 VLE 229 Score = 84.1 bits (206), Expect = 8e-17, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 6/96 (6%) Query: 14 WYMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 W+ +S +A+T L+G HG FL R S GD+ LSV +V+H I + + Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63 Query: 73 IGDQEFDHLPALLEFYKIHY-----LDTTTLIEPAP 103 G ++F L L+E+Y D T + P Sbjct: 64 YGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYP 99 >3PS5-A nrPDB Length = 595 Score = 91.4 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 13/123 (10%) Query: 14 WYMGPVSRQEAQTRLQGQRH-GMFLVRDSSTCPGDYVLSVSENS---------RVSHYII 63 WY G +S +A+T LQ + FLVR+S + PGD+VLSV + RV+H + Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKV 169 Query: 64 NSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAED 123 R G + FD L L+E +K ++ + A Y P + Sbjct: 170 MCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEASG---AFVYLRQPYYATRVNAADIENR 226 Query: 124 NLE 126 LE Sbjct: 227 VLE 229 Score = 82.9 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 6/96 (6%) Query: 14 WYMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK 72 W+ +S +A+T L+G HG FL R S GD+ LSV +V+H I + + Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYDL 63 Query: 73 IGDQEFDHLPALLEFYKIHY-----LDTTTLIEPAP 103 G ++F L L+E+Y D T + P Sbjct: 64 YGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYP 99 >3GF9-A nrPDB Length = 295 Score = 87.9 bits (216), Expect = 4e-18, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 1/59 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 V +YD+ N+ ++L F KG+++ ++ K + WW +G G+ P YV+ S P Sbjct: 21 VIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGE-INGVTGLFPSNYVKMTTDSDP 78 Score = 60.2 bits (144), Expect = 9e-10, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 30/61 (49%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 + I A ++ L+ G ++ V + W+GE+NG GLFP +VK+ +P Sbjct: 20 QVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTDSDPS 79 Query: 301 E 301 + Sbjct: 80 Q 80 >5M6U-B nrPDB Length = 724 Score = 86.8 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 6/102 (5%) Query: 9 SDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 D W +G +R +A+ L+G+R G FLVR+SS G Y SV + V H +IN Sbjct: 619 HDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVINKTAT 677 Query: 69 RR-FKIGDQEFDHLPALLEFYK----IHYLDTTTLIEPAPRY 105 F + L L+ Y+ + + D+ + P Y Sbjct: 678 GYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVY 719 Score = 79.8 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 32/142 (22%), Positives = 52/142 (36%), Gaps = 9/142 (6%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRD-SSTCPGDYVLSVSENSRVSHYIINSL 66 S + WY G +SR+E +L+ G FLVRD S+ GDY L++ + I Sbjct: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 386 Query: 67 PNRRFKIGDQEFDHLPALLEFYKIHYLDTT------TLIEPAPRYPSPPMGSVSAPNLPT 120 + F + L+ Y+ L L+ P +Y + V N+ Sbjct: 387 DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV--VKEDNIEA 444 Query: 121 AEDNLEYVRTLYDFPGNDAEDL 142 L T + + + L Sbjct: 445 VGKKLHEYNTQFQEKSREYDRL 466 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 36/122 (29%), Gaps = 18/122 (14%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVI-------IEKPEEQ--------WWSARNK-DGRVGM 172 R LYD+ ED+ G+IL + + + Q W + N+ G G Sbjct: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 Query: 173 IPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPS 232 P YVE + R P + + A++ A P Sbjct: 69 FPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQ--ALTLPDLAEQFAPPD 126 Query: 233 TQ 234 Sbjct: 127 IA 128 >3JV3-A nrPDB Length = 283 Score = 86.4 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 1/59 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 V +YD+ + ++L F KG+I+ ++ K + WW G+VG+ P YV+ P Sbjct: 5 VIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGE-VSGQVGLFPSNYVKLTTDMDP 62 Score = 62.9 bits (151), Expect = 1e-10, Method: Composition-based stats. Identities = 19/61 (31%), Positives = 29/61 (47%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 + I A + LA G I+ V W+GEV+G+ GLFP +VK+ +P Sbjct: 4 QVIGMYDYTAQNDDELAFSKGQIINVLNKEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPS 63 Query: 301 E 301 + Sbjct: 64 Q 64 >5VEI-A nrPDB Length = 110 Score = 86.4 bits (212), Expect = 2e-17, Method: Composition-based stats. Identities = 26/81 (32%), Positives = 42/81 (51%), Gaps = 1/81 (1%) Query: 111 GSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRV 170 A A+ L + +YDF +++L FKKG+ + I+ K ++ W+ GRV Sbjct: 20 FQGGAAQPAMAQGALLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGE-HHGRV 78 Query: 171 GMIPVPYVEKLVRSSPHGKHG 191 G+ P+ YVEKL S+ + G Sbjct: 79 GIFPISYVEKLTGSAAALRTG 99 Score = 51.3 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 25/53 (47%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 A A L+ + GD V + R +EGE +GR G+FP ++V+ Sbjct: 37 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKL 89 >2V1R-A nrPDB Length = 80 Score = 86.0 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 6/74 (8%) Query: 116 PNLPTAEDNLEYVRTLYDF-PGNDAEDLPFKKGEILVIIEKPEE-----QWWSARNKDGR 169 + P LE+ R LYDF P N ++ KKG+++ I+ K + WW R K+G Sbjct: 5 GSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGN 64 Query: 170 VGMIPVPYVEKLVR 183 +G IP Y+E + R Sbjct: 65 IGYIPYNYIEIIKR 78 Score = 34.8 bits (78), Expect = 0.043, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKV-TRMNING----QWEGEV-NGRKGLFPFTHVK 292 FA+A+ VP + +AL+ GD++ + ++ + G W+ NG G P+ +++ Sbjct: 16 FARALYDFVP-ENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIE 74 Query: 293 IF 294 I Sbjct: 75 II 76 >1GCQ-A nrPDB Length = 61 Score = 85.6 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 YV+ L+DF + +L F++G+ + +++ + WW G+ GM P YV + R+ Sbjct: 4 YVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACH-GQTGMFPRNYVTPVNRN 60 Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%), Gaps = 2/56 (3%) Query: 236 GPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHV 291 G + +A+ P + L GD + V + W+G +G+ G+FP +V Sbjct: 1 GSTYVQALFDFDP--QEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYV 54 >1N5Z-A nrPDB Length = 92 Score = 85.6 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 6/74 (8%) Query: 116 PNLPTAEDNLEYVRTLYDF-PGNDAEDLPFKKGEILVIIEKPEE-----QWWSARNKDGR 169 + P LE+ R LYDF P N ++ KKG+++ I+ K + WW R K+G Sbjct: 5 GSEPIDPSKLEFARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGN 64 Query: 170 VGMIPVPYVEKLVR 183 +G IP Y+E + R Sbjct: 65 IGYIPYNYIEIIKR 78 Score = 34.8 bits (78), Expect = 0.051, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKV-TRMNING----QWEGEV-NGRKGLFPFTHVK 292 FA+A+ VP + +AL+ GD++ + ++ + G W+ NG G P+ +++ Sbjct: 16 FARALYDFVP-ENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIE 74 Query: 293 IF 294 I Sbjct: 75 II 76 >4BNE-A nrPDB Length = 457 Score = 85.2 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 15/108 (13%) Query: 89 KIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLE--------------YVRTLYDF 134 + + + + E YP+ S + + + VR LYD+ Sbjct: 349 QPNKHSSVSSYEKNQSYPTDWSDEESNNPFSSTDAKGDTNPFDEDTSPVMEVRVRALYDY 408 Query: 135 PGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 G + ++L FK G+ L +E +EQ W R +G+VG+ P YVE + Sbjct: 409 EGQEQDELSFKAGDELTKMENEDEQGWCKGRLDNGQVGLYPANYVEPI 456 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 41/106 (38%), Gaps = 5/106 (4%) Query: 189 KHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRVP 248 KH + +S P ++ ++ P + P + + + Sbjct: 352 KHSSVSSYEKNQSYP-TDWSDEESNNPFSSTDAKGDT--NPFDEDTSPVMEVRVRALYDY 408 Query: 249 CAYDKTALALEVGD-IVKVTRMNINGQWEGEV-NGRKGLFPFTHVK 292 ++ L+ + GD + K+ + G +G + NG+ GL+P +V+ Sbjct: 409 EGQEQDELSFKAGDELTKMENEDEQGWCKGRLDNGQVGLYPANYVE 454 >1RPY-A nrPDB Length = 114 Score = 84.4 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 12 SAWYMGPVSR-QEAQTRLQGQR--HGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 W+ G +SR + AQ L G HG+F++R S T PG+ VL+ + + H ++ + Sbjct: 11 YPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGH 70 Query: 69 RRFKIGDQEFDHLPALLEFYKIH 91 + + F + +L + H Sbjct: 71 GQCHVQHLWFQSVFDMLRHFHTH 93 >4JGH-A nrPDB Length = 173 Score = 84.4 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 22/123 (17%) Query: 11 RSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVS-------ENSRVSH--- 60 ++ WY G ++ EA+ +L+ G FL+RDSS DY+L++S N R+ + Sbjct: 20 QTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSS--HSDYLLTISVKTSAGPTNLRIEYQDG 77 Query: 61 -YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPR------YPSPPMGSV 113 + ++S+ + K+ ++FD + L+++Y D T E APR Y + P+ + Sbjct: 78 KFRLDSIICVKSKL--KQFDSVVHLIDYYVQMCKDKRTGPE-APRNGTVHLYLTKPLYTS 134 Query: 114 SAP 116 + Sbjct: 135 APS 137 >2YUP-A nrPDB Length = 90 Score = 84.4 bits (207), Expect = 6e-17, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 3/90 (3%) Query: 111 GSVSAPNLPTAEDNLEYVRTL--YDFPGNDAEDLPFKKGEILVIIEKPEEQWWSAR-NKD 167 GS + P LEY + Y F G+ +L F+KGE + +I K E W+ R Sbjct: 1 GSSGSSGKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGT 60 Query: 168 GRVGMIPVPYVEKLVRSSPHGKHGNRNSNS 197 GR G+ P YV+ + S+ Sbjct: 61 GRQGIFPASYVQVSREPRLRLCDDSGPSSG 90 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEV--NGRKGLFPFTHVKI 293 + +A+ + + L+ G+ + + R +EG + GR+G+FP ++V++ Sbjct: 17 YGEAVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQV 73 >6F55-A nrPDB Length = 67 Score = 84.1 bits (206), Expect = 7e-17, Method: Composition-based stats. Identities = 26/56 (46%), Positives = 35/56 (62%), Gaps = 1/56 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 VR LYD+ G +A++L FK GE L+ I + +EQ W R G VG+ P YVEK+ Sbjct: 7 RVRALYDYTGQEADELSFKAGEELMKISEEDEQGWCKGRLLTGHVGLYPANYVEKV 62 >4N78-F nrPDB Length = 514 Score = 83.3 bits (204), Expect = 1e-16, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 109 PMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDG 168 + P LE V +YD+ + ++L F++G I+ +I+K ++ W+ +G Sbjct: 439 DPYAEEDPPWAPR-SYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGV-MNG 496 Query: 169 RVGMIPVPYVEKLVRSS 185 G+ P YVE ++ S Sbjct: 497 VTGLFPGNYVESIMHYS 513 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 27/54 (50%) Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 K + + L+ + G I+ V + N +G +EG +NG GLFP +V+ Sbjct: 454 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 507 >3HAJ-A nrPDB Length = 486 Score = 82.5 bits (202), Expect = 2e-16, Method: Composition-based stats. Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 1/56 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 VR LYD+ G + ++L FK G+ L +E +EQ W R +G+VG+ P YVE + Sbjct: 430 RVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 28/78 (35%), Gaps = 2/78 (2%) Query: 217 PAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGD-IVKVTRMNINGQW 275 P S P + + L+ + GD + K+ + G Sbjct: 406 PFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWC 465 Query: 276 EGEV-NGRKGLFPFTHVK 292 +G + NG+ GL+P +V+ Sbjct: 466 KGRLDNGQVGLYPANYVE 483 >4M4Z-A nrPDB Length = 170 Score = 82.1 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 29/85 (34%), Positives = 41/85 (48%), Gaps = 8/85 (9%) Query: 12 SAWYMGPVSRQEAQTRLQ--GQRHGMFLVRDSSTCPGDYVLSVSENS-----RVSHYIIN 64 W +SR++A+ L G G FL+R+S T G Y LSV + R+ HY I+ Sbjct: 69 HGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIH 128 Query: 65 SLPNRRFKIGDQ-EFDHLPALLEFY 88 L N I + F L AL++ Y Sbjct: 129 CLDNGWLYISPRLTFPSLQALVDHY 153 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNK-DGRVGMIPVPYVEKLVR 183 L FP +L + GE L I+ + + WW+ ++ GR IP +V K+ Sbjct: 14 AVALGSFPAGGPAELSLRLGEPLTIVSE-DGDWWTVLSEVSGREYNIPSVHVAKVSH 69 >2ED1-A nrPDB Length = 76 Score = 82.1 bits (201), Expect = 3e-16, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 2/72 (2%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA--RNKDGRVGMIPVPY 177 ++ + + V+T+YD ++ ++L F +GE++++ + +++WW + R G+ PV + Sbjct: 5 SSGNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSF 64 Query: 178 VEKLVRSSPHGK 189 V L S P Sbjct: 65 VHILSDSGPSSG 76 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 27/71 (38%), Gaps = 3/71 (4%) Query: 232 STQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNG---RKGLFPF 288 S +G + A + L G+++ VT W G + G RKG+FP Sbjct: 3 SGSSGNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPV 62 Query: 289 THVKIFDPQNP 299 + V I P Sbjct: 63 SFVHILSDSGP 73 >2X3W-D nrPDB Length = 60 Score = 81.0 bits (198), Expect = 6e-16, Method: Composition-based stats. Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 1/56 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ-WWSARNKDGRVGMIPVPYVEKL 181 VR LYD+ G + ++L FK G+ L + + +EQ W R G++G+ P YVE + Sbjct: 5 RVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 60 >2ED0-A nrPDB Length = 78 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 3/75 (4%) Query: 111 GSVSAPNLPT--AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDG 168 GS + P LE V +YD+ + ++L F++G I+ +I+K ++ W+ +G Sbjct: 1 GSSGSSGDPPWAPRSYLEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGV-MNG 59 Query: 169 RVGMIPVPYVEKLVR 183 G+ P YVE + Sbjct: 60 VTGLFPGNYVESISG 74 Score = 47.5 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 16/54 (29%), Positives = 27/54 (50%) Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 K + + L+ + G I+ V + N +G +EG +NG GLFP +V+ Sbjct: 17 LEKVVAIYDYTKDKEDELSFQEGAIIYVIKKNDDGWYEGVMNGVTGLFPGNYVE 70 >2PLE-A nrPDB Length = 105 Score = 78.3 bits (191), Expect = 4e-15, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 9 SDRSAWYMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLP 67 + WY ++R +A+ L R G FLVR P Y +S ++ H + Sbjct: 6 HESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR-NEPNSYAISFRAEGKIKHCRVQ-QE 63 Query: 68 NRRFKIGDQEFDHLPALLEFYKIHYL 93 + +G+ EFD L L+ +Y+ H L Sbjct: 64 GQTVMLGNSEFDSLVDLISYYEKHPL 89 >2YDL-A nrPDB Length = 69 Score = 77.5 bits (189), Expect = 7e-15, Method: Composition-based stats. Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIFDP 296 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ P Sbjct: 13 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPP 61 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKP--EEQWWSARNKDGRVGMIPVPYVEKL 181 +Y + ++ + + ++L K+G+I+ +I K + WW +GR G+ P +V+ L Sbjct: 3 DYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGE-LNGRRGVFPDNFVKLL 59 >2K6D-A nrPDB Length = 62 Score = 77.5 bits (189), Expect = 7e-15, Method: Composition-based stats. Identities = 20/49 (40%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIFDP 296 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ P Sbjct: 14 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPP 62 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKP--EEQWWSARNKDGRVGMIPVPYVEKL 181 +Y + ++ + + ++L K+G+I+ +I K + WW +GR G+ P +V+ L Sbjct: 4 DYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGE-LNGRRGVFPDNFVKLL 60 >1NM7-A nrPDB Length = 69 Score = 76.7 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 6/61 (9%) Query: 127 YVRTLYDF-PGNDAEDLPFKKGEILVIIEKPEE-----QWWSARNKDGRVGMIPVPYVEK 180 + R LYDF P N ++ KKG+++ I+ K + WW R K+G +G IP Y+E Sbjct: 9 FARALYDFVPENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIEI 68 Query: 181 L 181 + Sbjct: 69 I 69 Score = 35.9 bits (81), Expect = 0.020, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 32/62 (51%), Gaps = 7/62 (11%) Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKV-TRMNING----QWEGEV-NGRKGLFPFTHVK 292 FA+A+ VP + +AL+ GD++ + ++ + G W+ NG G P+ +++ Sbjct: 9 FARALYDFVP-ENPEMEVALKKGDLMAILSKKDPLGRDSDWWKVRTKNGNIGYIPYNYIE 67 Query: 293 IF 294 I Sbjct: 68 II 69 >2K9G-A nrPDB Length = 73 Score = 76.7 bits (187), Expect = 1e-14, Method: Composition-based stats. Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIFDPQNPDE 301 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ P E Sbjct: 20 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKE 73 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 32/58 (55%), Gaps = 3/58 (5%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKP--EEQWWSARNKDGRVGMIPVPYVEKL 181 +Y + ++ + + ++L K+G+I+ +I K + WW +GR G+ P +V+ L Sbjct: 10 DYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGE-LNGRRGVFPDNFVKLL 66 >2RQT-A nrPDB Length = 61 Score = 76.4 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA--RNKDGRVGMIPVPYVEKLV 182 + V+T+YD ++ ++L F +GE++++ + +++WW + R G+ PV +V L Sbjct: 1 VRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHILS 60 Query: 183 R 183 Sbjct: 61 D 61 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 3/57 (5%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNG---RKGLFPFTHVKIF 294 + A + L G+++ VT W G + G RKG+FP + V I Sbjct: 3 RVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHIL 59 >2EOB-A nrPDB Length = 124 Score = 76.4 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 35/88 (39%), Gaps = 2/88 (2%) Query: 7 DSSDRSAWYMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINS 65 + + WY +SR EA+ L R G FL+R Y ++ +V H IN Sbjct: 14 NPHESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGT-DSYAITFRARGKVKHCRINR 72 Query: 66 LPNRRFKIGDQEFDHLPALLEFYKIHYL 93 F+ L L+ +Y+ H L Sbjct: 73 DGRHFVLGTSAYFESLVELVSYYEKHAL 100 >4E93-A nrPDB Length = 377 Score = 74.4 bits (181), Expect = 5e-14, Method: Composition-based stats. Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 4/80 (5%) Query: 8 SSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLP 67 WY G + R E L G FLVR+S +YVLSV + H+II SL Sbjct: 9 PLHEQLWYHGAIPRAEVAELLVHS--GDFLVRESQGKQ-EYVLSVLWDGLPRHFIIQSLD 65 Query: 68 NRRFKIGDQEFDHLPALLEF 87 N +++ + F +P L++ Sbjct: 66 NL-YRLEGEGFPSIPLLIDH 84 >3EHQ-A nrPDB Length = 222 Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 1/76 (1%) Query: 124 NLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVR 183 ++ R LY F ++L ++G+I+ I + + WW +K GR G+IP YV + Sbjct: 13 QVKVFRALYTFEPRTPDELYIEEGDIIYITDMSDTNWWKGTSK-GRTGLIPSNYVAEQAE 71 Query: 184 SSPHGKHGNRNSNSYG 199 S + H + Sbjct: 72 SIDNPLHEAAKRGNLS 87 Score = 49.8 bits (117), Expect = 1e-06, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 21/50 (42%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHV 291 L +E GDI+ +T M+ W+G GR GL P +V Sbjct: 17 FRALYTFEPRTPDELYIEEGDIIYITDMSDTNWWKGTSKGRTGLIPSNYV 66 >2EKX-A nrPDB Length = 110 Score = 71.7 bits (174), Expect = 3e-13, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 46/109 (42%), Gaps = 10/109 (9%) Query: 3 SARFDSSDRSAWYMGPVSRQEAQTRL-QGQRHGMFLVRDSSTCPGDYVLSVSEN------ 55 S+ D W+ G +SR +++ L Q + G F+VR+S + G Y +S+ Sbjct: 2 SSGSSGLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNS-SQVGMYTVSLFSKAVNDKK 60 Query: 56 SRVSHYIINSLPNRRFKIGDQE-FDHLPALLEFYKIHYLDTTTLIEPAP 103 V HY +++ + + + FD +P L+ Y H P Sbjct: 61 GTVKHYHVHTNAENKLYLAENYCFDSIPKLI-HYHQHNSAGMITRLRHP 108 >2DA9-A nrPDB Length = 70 Score = 71.4 bits (173), Expect = 5e-13, Method: Composition-based stats. Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 2/47 (4%) Query: 250 AYDKTALALEVGDIVKVTRMNI--NGQWEGEVNGRKGLFPFTHVKIF 294 A + L ++ GDIV + + G WEGE+NGR+G+FP VK+ Sbjct: 18 AQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLL 64 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 35/66 (53%), Gaps = 3/66 (4%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKP--EEQWWSARNKDGRVGMIPVPY 177 ++ + +Y + ++ + + ++L K+G+I+ +I K + WW +GR G+ P + Sbjct: 2 SSGSSGDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGE-LNGRRGVFPDNF 60 Query: 178 VEKLVR 183 V+ L Sbjct: 61 VKLLSG 66 >3CXL-A nrPDB Length = 463 Score = 71.0 bits (172), Expect = 6e-13, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 15 YMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIG 74 + G +SR+ A L G +L+R+S PG Y L++ S+ ++ + + + +G Sbjct: 54 FHGMISREAADQLLI-VAEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYY--DGKHFVG 110 Query: 75 DQEFDHLPALL 85 ++ F+ + L+ Sbjct: 111 EKRFESIHDLV 121 >1XA6-A nrPDB Length = 466 Score = 69.8 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 46/98 (46%), Gaps = 3/98 (3%) Query: 15 YMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIG 74 + G +SR++A L G G +++R+S PG Y L++ ++ +Y + + + +G Sbjct: 58 FHGIISREQADELL-GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRLFH--DGKHFVG 114 Query: 75 DQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGS 112 ++ F+ + L+ I T E + + P+ Sbjct: 115 EKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIYE 152 >1GBQ-A nrPDB Length = 74 Score = 69.8 bits (169), Expect = 1e-12, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKP-EEQWWSARNKDGRVGMIPVPYVEK 180 YDF ++L FK+G+IL ++ + ++ W+ A +G+ G IP Y+E Sbjct: 12 AIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAE-LNGKDGFIPKNYIEM 64 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNIN-GQWEGEVNGRKGLFPFTHVKIFD 295 +AI K A L+ + GDI+KV + ++ E+NG+ G P ++++ Sbjct: 11 EAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKP 66 >2PZ1-A nrPDB Length = 466 Score = 68.3 bits (165), Expect = 4e-12, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 1/77 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187 L+D D ++L FK G+++ +++ +WW R DG G P +V V Sbjct: 33 AEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADG-EGWFPASFVRLRVNQDEP 91 Query: 188 GKHGNRNSNSYGIPEPA 204 + + G + Sbjct: 92 ADDDAPLAGNSGAEDGG 108 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 25/53 (47%), Gaps = 1/53 (1%) Query: 252 DKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI-FDPQNPDENE 303 D L + GD+++V W G V +G FP + V++ + P +++ Sbjct: 43 DDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDD 95 >6C5X-D nrPDB Length = 164 Score = 67.9 bits (164), Expect = 6e-12, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 34/97 (35%), Gaps = 1/97 (1%) Query: 9 SDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 D +Y GP+ A +L+ + G FL+RDS + +SV I Sbjct: 27 LDTCGFYWGPMDVNVAHDKLKSEPIGTFLIRDSKQKNCFFAISVKTARETVSIRIKFHAG 86 Query: 69 RRFKIGDQE-FDHLPALLEFYKIHYLDTTTLIEPAPR 104 + G +E F L L+E Y R Sbjct: 87 KFSLDGSKELFSCLFQLVEHYMTSPKKMLVSPLRKVR 123 >1K4U-S nrPDB Length = 62 Score = 67.5 bits (163), Expect = 7e-12, Method: Composition-based stats. Identities = 18/52 (34%), Positives = 32/52 (61%), Gaps = 1/52 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 V L+ + EDL F++G+I++++ K E+W +K G+VG+ P +VE Sbjct: 8 VEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGESK-GKVGIFPKVFVE 58 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 21/53 (39%) Query: 240 AKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 ++ A L + GDI+ V EGE G+ G+FP V+ Sbjct: 6 SQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGESKGKVGIFPKVFVE 58 >6C7Y-B nrPDB Length = 117 Score = 67.5 bits (163), Expect = 8e-12, Method: Composition-based stats. Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 1/81 (1%) Query: 9 SDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 D +Y GP++ A +L+ + G FL+RDS+ + +SV + + IN Sbjct: 23 LDACGFYWGPLTVSAAHEKLKSEPEGTFLIRDSTQKNCFFAISVKTATGPTSIRINFQTG 82 Query: 69 RRFKIGDQE-FDHLPALLEFY 88 R G +E FD L LLE Y Sbjct: 83 RFSLDGSKETFDCLFKLLEHY 103 >2VIF-A nrPDB Length = 141 Score = 67.1 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 9 SDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 + WY GP++R EA+ +L G FLVRDSS LS + + H I N Sbjct: 21 LAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIE-HSN 79 Query: 69 RRFKIGD----QEFDHLPALLEF 87 RF + + + L+E Sbjct: 80 GRFSFYEQPDVEGHTSIVDLIEH 102 >2NWM-A nrPDB Length = 65 Score = 66.7 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 31/57 (54%), Gaps = 1/57 (1%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 ++ R +DF ++L +KG+I+ I ++ ++ W GR+G+ P YVE L Sbjct: 1 MKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-HHGRLGIFPANYVEVL 56 Score = 55.6 bits (132), Expect = 2e-08, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 25/51 (49%) Query: 245 KRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFD 295 K A L L+ GDIV + + EGE +GR G+FP +V++ Sbjct: 7 KFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVLP 57 >2DYB-A nrPDB Length = 341 Score = 66.3 bits (160), Expect = 1e-11, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 41/101 (40%), Gaps = 5/101 (4%) Query: 87 FYKIHYLDTTTLIEPAPRYPSP---PMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLP 143 F+ D+ + + A R P + SVS L+DF GN +L Sbjct: 134 FFYQSPYDSEQVPQ-ALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELN 192 Query: 144 FKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 FK G+++ ++ + + W G G+ P+ +V+ L Sbjct: 193 FKAGDVIFLLSRINKDWLEG-TVRGATGIFPLSFVKILKDF 232 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 39/103 (37%), Gaps = 7/103 (6%) Query: 207 YAQPQTTTPLPAV------SGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEV 260 Y P + +P +++P ++ + +A K L + Sbjct: 136 YQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKA 195 Query: 261 GDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE 303 GD++ + EG V G G+FP + VKI P+E++ Sbjct: 196 GDVIFLLSRINKDWLEGTVRGATGIFPLSFVKIL-KDFPEEDD 237 >2DLM-A nrPDB Length = 68 Score = 65.2 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 ++ + + R +DF ++L +KG+I+ I ++ ++ W GR+G+ P YVE Sbjct: 2 SSGSSGKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGE-HHGRLGIFPANYVE 60 Query: 180 KLVR 183 L Sbjct: 61 VLSG 64 Score = 51.7 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 25/50 (50%) Query: 245 KRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 K A L L+ GDIV + + EGE +GR G+FP +V++ Sbjct: 13 KFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVL 62 >5NXJ-A nrPDB Length = 60 Score = 64.4 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 LYD+ +++ F +I+ IE ++ WW K GR G+ P YVE Sbjct: 7 AIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVE 57 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 24/53 (45%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 AI A ++ + DI+ M +G W G GR GLFP +V++ Sbjct: 6 TAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 58 >3ULR-B nrPDB Length = 65 Score = 64.4 bits (155), Expect = 6e-11, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 LYD+ +++ F +I+ IE ++ WW K GR G+ P YVE Sbjct: 12 AIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVE 62 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 24/53 (45%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKI 293 AI A ++ + DI+ M +G W G GR GLFP +V++ Sbjct: 11 TAIALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVEL 63 >4MT6-A nrPDB Length = 456 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 27/66 (40%), Gaps = 1/66 (1%) Query: 113 VSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGM 172 + D++ ++D +L FK G+++ +++ + WW + D G Sbjct: 5 RGGSGMLITGDSIVSAEAVWDHVTMANRELAFKAGDVIKVLDASNKDWWWGQ-IDDEEGW 63 Query: 173 IPVPYV 178 P +V Sbjct: 64 FPASFV 69 Score = 45.9 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 25/43 (58%) Query: 255 ALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQ 297 LA + GD++KV + W G+++ +G FP + V+++ Q Sbjct: 33 ELAFKAGDVIKVLDASNKDWWWGQIDDEEGWFPASFVRLWVNQ 75 >4GL9-E nrPDB Length = 143 Score = 63.3 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 32/94 (34%), Gaps = 9/94 (9%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYII 63 S +Y V+ EA L + G FL+RDSS + LSV S + I Sbjct: 20 NAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRI 79 Query: 64 NSLPNRRFKIGDQ--------EFDHLPALLEFYK 89 F + FD + L+ Y Sbjct: 80 QC-EGGSFSLQSDPRSTQPVPRFDCVLKLVHHYM 112 >2BBU-A nrPDB Length = 164 Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 42/131 (32%), Gaps = 18/131 (13%) Query: 1 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH 60 + S +Y V+ EA L + G FL+RDSS + LSV S + Sbjct: 12 LVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKN 71 Query: 61 YIINSLPNRRFKIGDQ--------EFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMG- 111 I F + FD + L+ Y P + PP Sbjct: 72 LRIQC-EGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMP--------PPGTPSFSLPPTEP 122 Query: 112 SVSAPNLPTAE 122 S P P A+ Sbjct: 123 SSEVPEQPPAQ 133 >2EQI-A nrPDB Length = 69 Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 27/64 (42%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 ++ + V+ LYD+ +++L F +G ++ + K WW P YVE Sbjct: 2 SSGSSGRTVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVE 61 Query: 180 KLVR 183 + Sbjct: 62 DISG 65 Score = 34.0 bits (76), Expect = 0.076, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 16/53 (30%), Gaps = 1/53 (1%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRK-GLFPFTHVK 292 A L G ++ G W+G+ R FP +V+ Sbjct: 9 TVKALYDYKAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVE 61 >1X69-A nrPDB Length = 79 Score = 62.5 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 2/62 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187 LYD+ +++ F +I+ IE ++ WW K GR G+ P YVE L +S P Sbjct: 20 AVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCK-GRYGLFPANYVE-LRQSGPS 77 Query: 188 GK 189 Sbjct: 78 SG 79 Score = 47.9 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%) Query: 230 LPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFT 289 + A+ A ++ + DI+ M +G W G GR GLFP Sbjct: 8 TYDEYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPAN 67 Query: 290 HVKI 293 +V++ Sbjct: 68 YVEL 71 >2O2O-A nrPDB Length = 92 Score = 62.5 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 132 YDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGK 189 + + + ++L K G+I+ ++ + EE WW +G+ GM P ++++L S Sbjct: 25 FSYLPQNDDELELKVGDIIEVVGEVEEGWWEGV-LNGKTGMFPSNFIKELSGESDELG 81 Score = 53.6 bits (127), Expect = 1e-07, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 28/50 (56%) Query: 251 YDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 + L L+VGDI++V G WEG +NG+ G+FP +K ++ + Sbjct: 30 QNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDE 79 >5XHZ-A nrPDB Length = 66 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVR 183 + + + + ++L K G+I+ ++ + EE WW +G+ GM P ++++L Sbjct: 10 RRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGV-LNGKTGMFPSNFIKELSG 66 Score = 53.2 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 25/44 (56%) Query: 251 YDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 + L L+VGDI++V G WEG +NG+ G+FP +K Sbjct: 21 QNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKEL 64 >1Z9Q-A nrPDB Length = 79 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 L+DF GN +L FK G+++ ++ + + W G G+ P+ +V+ L Sbjct: 20 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEG-TVRGATGIFPLSFVKILKDF 76 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 300 +A K L + GD++ + EG V G G+FP + VKI P+ Sbjct: 20 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKIL-KDFPE 78 Query: 301 E 301 E Sbjct: 79 E 79 >1WI7-A nrPDB Length = 68 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 33/64 (51%), Gaps = 1/64 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 ++ + + + + + ++L K G+I+ ++ + EE WW +G+ GM P +++ Sbjct: 2 SSGSSGRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGV-LNGKTGMFPSNFIK 60 Query: 180 KLVR 183 +L Sbjct: 61 ELSG 64 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 25/44 (56%) Query: 251 YDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 + L L+VGDI++V G WEG +NG+ G+FP +K Sbjct: 19 QNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKEL 62 >2HMH-A nrPDB Length = 152 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 32/94 (34%), Gaps = 9/94 (9%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYII 63 S +Y V+ EA L + G FL+RDSS + LSV S + I Sbjct: 26 NAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRI 85 Query: 64 NSLPNRRFKIGDQ--------EFDHLPALLEFYK 89 F + FD + L+ Y Sbjct: 86 QC-EGGSFSLQSDPRSTQPVPRFDCVLKLVHHYM 118 >1M27-A nrPDB Length = 104 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 15 YMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK- 72 Y G +SR+ + L G +L+RDS + PG Y L V + + Y ++ + Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66 Query: 73 -----IGDQEFDHLPALLEFYK 89 + + F + L+ ++ Sbjct: 67 ETAPGVHKRYFRKIKNLISAFQ 88 >1KA6-A nrPDB Length = 128 Score = 61.7 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 7/82 (8%) Query: 15 YMGPVSRQEAQTRLQG-QRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFK- 72 Y G +SR+ + L G +L+RDS + PG Y L V + + Y ++ + Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66 Query: 73 -----IGDQEFDHLPALLEFYK 89 + + F + L+ ++ Sbjct: 67 ETAPGVHKRYFRKIKNLISAFQ 88 >2HSP-A nrPDB Length = 71 Score = 61.7 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 2/65 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187 V+ L+D+ ++L F K I+ +EK E WW + P YVE++V P Sbjct: 9 VKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVN--PE 66 Query: 188 GKHGN 192 G H + Sbjct: 67 GIHRD 71 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 3/60 (5%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKG-LFPFTHVKIFDPQNPD 300 A + L I++ G W G+ G+K FP +V+ + NP+ Sbjct: 9 VKALFDYKAQREDELTFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVE--EMVNPE 66 >1YWO-A nrPDB Length = 64 Score = 61.7 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 26/54 (48%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 V+ L+D+ ++L F K I+ +EK + WW + P YVE++ Sbjct: 9 VKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVEEM 62 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 21/58 (36%), Gaps = 2/58 (3%) Query: 237 PVF-AKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKG-LFPFTHVK 292 P F + A + L I++ G W G+ G+K FP +V+ Sbjct: 3 PTFKSAVKALFDYKAQREDELTFTKSAIIQNVEKQDGGWWRGDYGGKKQLWFPSNYVE 60 >1W6X-A nrPDB Length = 60 Score = 60.6 bits (145), Expect = 9e-10, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 28/56 (50%), Gaps = 1/56 (1%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLV 182 L+DF GN +L FK G+++ ++ + + W G G+ P+ +V+ L Sbjct: 6 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEG-TVRGATGIFPLSFVKILK 60 Score = 40.5 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 22/54 (40%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 +A K L + GD++ + EG V G G+FP + VKI Sbjct: 6 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKIL 59 >1UEC-A nrPDB Length = 193 Score = 59.4 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 61/174 (35%), Gaps = 44/174 (25%) Query: 119 PTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYV 178 T L+ R + D+ ++ G+++ ++EK E WW + K R G IP ++ Sbjct: 5 ITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-GWIPASFL 63 Query: 179 EKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPV 238 E L +T P P +G P AI Sbjct: 64 EPLDSPD-------------------------ETEDPEPNYAGEPYVAI----------- 87 Query: 239 FAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 + A + ++L G+ V+V ++G W + G FP +++ Sbjct: 88 -------KAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 134 Score = 47.1 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 254 TALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE 303 + +AL GD+V+V + +G W ++ ++G P + ++ D +PDE E Sbjct: 26 SEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLD--SPDETE 73 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 31/78 (39%), Gaps = 1/78 (1%) Query: 103 PRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWS 162 P P+ S P E + + + +++ +GE + +I K + WW Sbjct: 59 PASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWV 118 Query: 163 ARNKDGRVGMIPVPYVEK 180 R KD G P Y++K Sbjct: 119 IR-KDDVTGYFPSMYLQK 135 >1OV3-A nrPDB Length = 138 Score = 59.0 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 60/168 (35%), Gaps = 44/168 (26%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRS 184 L+ R + D+ ++ G+++ ++EK E WW + K R G IP ++E L Sbjct: 11 LQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKR-GWIPASFLEPLDSP 69 Query: 185 SPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQ 244 +T P P +G P AI Sbjct: 70 D-------------------------ETEDPEPNYAGEPYVAI----------------- 87 Query: 245 KRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 + A + ++L G+ V+V ++G W + G FP +++ Sbjct: 88 -KAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQ 134 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 254 TALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPDENE 303 + +AL GD+V+V + +G W ++ ++G P + ++ D +PDE E Sbjct: 26 SEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLD--SPDETE 73 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 31/78 (39%), Gaps = 1/78 (1%) Query: 103 PRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWS 162 P P+ S P E + + + +++ +GE + +I K + WW Sbjct: 59 PASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWV 118 Query: 163 ARNKDGRVGMIPVPYVEK 180 R KD G P Y++K Sbjct: 119 IR-KDDVTGYFPSMYLQK 135 >2DJQ-A nrPDB Length = 68 Score = 57.1 bits (136), Expect = 9e-09, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 ++ + + L ++ G + DL F KG+++++ + +E W+ +G G+ P VE Sbjct: 2 SSGSSGPRAKALCNYRGKNPGDLKFNKGDVILLRRQLDENWYQGE-INGVSGIFPASSVE 60 Query: 180 KLVR 183 + Sbjct: 61 VISG 64 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 23/44 (52%) Query: 251 YDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIF 294 + L GD++ + R ++GE+NG G+FP + V++ Sbjct: 19 KNPGDLKFNKGDVILLRRQLDENWYQGEINGVSGIFPASSVEVI 62 >5O2M-A nrPDB Length = 81 Score = 57.1 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEE--QWWSARNKDGRVGMIPVPYVEKLVR 183 + LYD ++L F+KG+I+ ++E+ + W + GR G++P ++ LV Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVG 67 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNI---NGQWEGEVNGRKGLFPFTHVKIF 294 A A L+ GDI+ V + +G W ++GR+G+ P +KI Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKIL 65 >5JMQ-A nrPDB Length = 446 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 28/63 (44%), Gaps = 2/63 (3%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYV-EKLVRS 184 E + D+ D L F +GE ++I+ + WW + G G IP ++ ++L Sbjct: 46 EEFVAIADYTATDETQLSFLRGEKILILRQTTADWWWGE-RAGCCGYIPANHLGKQLEEY 104 Query: 185 SPH 187 P Sbjct: 105 DPE 107 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 39/113 (34%), Gaps = 8/113 (7%) Query: 199 GIPEPAHAYAQPQTTTPL----PAVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKT 254 G+ P P+ P G + Q + + A D+T Sbjct: 1 GMEAPGEGPCSESQVIPVLEEDPVDYGCEMQLLQDGAQLQLQLQPEEFVAIADYTATDET 60 Query: 255 ALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTH----VKIFDPQNPDENE 303 L+ G+ + + R W GE G G P H ++ +DP++ ++E Sbjct: 61 QLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHLGKQLEEYDPEDTWQDE 113 >2IZV-A nrPDB Length = 187 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 42/108 (38%), Gaps = 8/108 (7%) Query: 9 SDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPN 68 + + Y G + + A+ L+G+ G FL+RDS+ + +S SR H I + Sbjct: 31 INNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYSRSLHARIEQWNH 90 Query: 69 RRFKIGDQ----EFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGS 112 + LLE YK D + + P +P + + Sbjct: 91 NFSFDAHDPCVFHSPDITGLLEHYK----DPSACMFFEPLLSTPLIRT 134 >5O2Q-A nrPDB Length = 99 Score = 56.3 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEE--QWWSARNKDGRVGMIPVPYVEKLVR 183 + LYD ++L F+KG+I+ ++E+ + W + GR G++P ++ LV Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVG 67 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNI---NGQWEGEVNGRKGLFPFTHVKIF 294 A A L+ GDI+ V + +G W ++GR+G+ P +KI Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKIL 65 >5O2P-A nrPDB Length = 100 Score = 55.9 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 31/58 (53%), Gaps = 2/58 (3%) Query: 128 VRTLYDFPGNDAEDLPFKKGEILVIIEKPEE--QWWSARNKDGRVGMIPVPYVEKLVR 183 + LYD ++L F+KG+I+ ++E+ + W + GR G++P ++ LV Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKILVG 67 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNI---NGQWEGEVNGRKGLFPFTHVKIF 294 A A L+ GDI+ V + +G W ++GR+G+ P +KI Sbjct: 10 AKALYDNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQGIVPGNRLKIL 65 >5NP2-A nrPDB Length = 61 Score = 55.6 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 28/62 (45%), Gaps = 2/62 (3%) Query: 122 EDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIE-KPEEQWWSARNKDGRVGMIPVPYVEK 180 ++ LYDF + L KGE L ++ +W A+ K+G+ G +P Y+ Sbjct: 1 GSHMNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQ-GWVPSNYITP 59 Query: 181 LV 182 + Sbjct: 60 VN 61 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNINGQW-EGEVNGRKGLFPFTHV 291 + A L++ G+ ++V N NG+W E + +G P ++ Sbjct: 7 FVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYI 57 >4WSI-A nrPDB Length = 394 Score = 55.2 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 28/167 (16%), Positives = 54/167 (32%), Gaps = 47/167 (28%) Query: 80 HLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGND- 138 + + + + T ++ P+ + PP A++ + +V+ +D+ +D Sbjct: 82 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPP-----------AKETVIHVKAHFDYDPSDD 130 Query: 139 ------AEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKHGN 192 L F+KG+IL +I + + WW A + G+ Sbjct: 131 PYVPCRELGLSFQKGDILHVISQEDPNWWQA------------------------YREGD 166 Query: 193 RNSNSYGIPEPAH----AYAQPQTTTPLPAVSGSPGAAITPLPSTQN 235 ++ P Y + PA P I P QN Sbjct: 167 EDNQPLAGLVPGKEEILTYEEMSLYHQ-PANRKRPIILIGPQNCGQN 212 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 33/117 (28%), Gaps = 13/117 (11%) Query: 178 VEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVS---GSPGAAITPLPSTQ 234 + ++V+ K G + + +S G+ + P + Sbjct: 49 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIK 108 Query: 235 NGPVFAKAIQKRVPCAYDKTA----------LALEVGDIVKVTRMNINGQWEGEVNG 281 P I + YD + L+ + GDI+ V W+ G Sbjct: 109 PPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREG 165 >2M0Y-A nrPDB Length = 74 Score = 54.0 bits (128), Expect = 8e-08, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN--KDGRVGMIPVPY 177 + +Y Y++ A++L + G+ + I+ + E W+ K + G+ P Y Sbjct: 6 PTKREEKYGVAFYNYDARGADELSLQIGDTVHIL-ETYEGWYRGYTLRKKSKKGIFPASY 64 Query: 178 VE 179 + Sbjct: 65 IH 66 >2V1Q-A nrPDB Length = 60 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 30/59 (50%), Gaps = 2/59 (3%) Query: 125 LEYVRTLYDFPGNDAEDLPFKKGEILVII-EKPEEQWWSARN-KDGRVGMIPVPYVEKL 181 +E YDF ++L K G+ + I+ +K + WW + G+ G++P ++E + Sbjct: 2 MERGIVQYDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVDSGKSGLVPAQFIEPV 60 >1I07-A nrPDB Length = 60 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVP 176 +Y ++ YDF ++ +L K ++L I++ QWW RN G G +P Sbjct: 2 KYAKSKYDFVARNSSELSVMKDDVLEILDDR-RQWWKVRNASGDSGFVPNN 51 >1WXU-A nrPDB Length = 93 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 5/90 (5%) Query: 112 SVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ----WWSARNKD 167 S N + ED+ R YDF E++ F+ G++L + K ++ W A Sbjct: 4 GSSGTNWASGEDDHVVARAEYDFVAVSDEEISFRAGDMLNLALKEQQPKVRGWLLASLDG 63 Query: 168 GRVGMIPVPYVEKL-VRSSPHGKHGNRNSN 196 G+IP YV+ L R +S Sbjct: 64 QTTGLIPANYVKILGKRRGRKTIESGPSSG 93 >2CUC-A nrPDB Length = 70 Score = 52.5 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPVPYV 178 ++ + L+ + + E+L +KGE + ++ K ++ W + GR G+ P YV Sbjct: 2 SSGSSGNMFVALHTYSAHRPEELDLQKGEGIRVLGKYQDGWLKGLSLLTGRTGIFPSDYV 61 Query: 179 EKLVR 183 + Sbjct: 62 IPVSG 66 Score = 35.5 bits (80), Expect = 0.030, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 24/52 (46%), Gaps = 2/52 (3%) Query: 242 AIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEG--EVNGRKGLFPFTHV 291 + A+ L L+ G+ ++V +G +G + GR G+FP +V Sbjct: 10 FVALHTYSAHRPEELDLQKGEGIRVLGKYQDGWLKGLSLLTGRTGIFPSDYV 61 >1UHF-A nrPDB Length = 69 Score = 52.1 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSS 185 E LY + + DL F +GE +++ +K + +WW+ + R G+ P YV+ S Sbjct: 9 EEYIALYPYSSVEPGDLTFTEGEEILVTQK-DGEWWTG-SIGDRSGIFPSNYVKP-KDSG 65 Query: 186 PHGK 189 P Sbjct: 66 PSSG 69 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 23/52 (44%), Gaps = 1/52 (1%) Query: 241 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 + I + + L G+ + VT+ + W G + R G+FP +VK Sbjct: 10 EYIALYPYSSVEPGDLTFTEGEEILVTQKDGE-WWTGSIGDRSGIFPSNYVK 60 >1UGV-A nrPDB Length = 72 Score = 51.7 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 ++ + LY +L F G + + +E W +G+ G+IP YVE Sbjct: 5 SSGTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVE 64 Query: 180 KLVR 183 L Sbjct: 65 FLSG 68 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 232 STQNGPVFAKAIQKRVPCAYDKTALALEVGDIV-KVTRMNINGQWEGEVNGRKGLFPFTH 290 S +G F KA A + L+ G + V G EG +NG+ GL P + Sbjct: 3 SGSSGTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENY 62 Query: 291 VKIF 294 V+ Sbjct: 63 VEFL 66 >4IIO-A nrPDB Length = 66 Score = 51.3 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 2/61 (3%) Query: 121 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 180 A+ L + L + L F K +I+ ++E+ E WW GR G P YV+ Sbjct: 4 AQGALLKAQALCSWTAKKDNHLNFSKHDIITVLEQQ-ENWWFGEVHGGR-GWFPKSYVKI 61 Query: 181 L 181 + Sbjct: 62 I 62 Score = 45.5 bits (106), Expect = 3e-05, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 250 AYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFD 295 A L DI+ V N W GEV+G +G FP ++VKI Sbjct: 19 AKKDNHLNFSKHDIITVLEQQEN-WWFGEVHGGRGWFPKSYVKIIP 63 >2MIO-A nrPDB Length = 70 Score = 50.9 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 25/56 (44%) Query: 126 EYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 R +Y + +L F+ G I ++ E W +G+ G+IP YV+ L Sbjct: 15 RKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL 70 Score = 41.7 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Query: 248 PC-AYDKTALALEVGDIVKVTRMNIN-GQWEGEVNGRKGLFPFTHVKIF 294 PC A + L+ E+G I + + + G EG +NG++GL P +VK+ Sbjct: 22 PCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRGLIPQNYVKLL 70 >2JT4-A nrPDB Length = 71 Score = 50.9 bits (120), Expect = 6e-07, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 132 YDFPGNDAEDLPFKKGEILVII-EKPEEQWWSARN-KDGRVGMIPVPYVEKLVR 183 YDF ++L K G+ + I+ +K + WW + G+ G++P ++E + Sbjct: 13 YDFMAESQDELTIKSGDKVYILDDKKSKDWWMCQLVDSGKSGLVPAQFIEPVRD 66 >1UE9-A nrPDB Length = 80 Score = 50.6 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 5/54 (9%) Query: 250 AYDKTALALEVGDIVKVTRMNINGQWEGEVNGR-----KGLFPFTHVKIFDPQN 298 A L+L G ++ + + N +G W+GE+ R KG FP +HVK+ P + Sbjct: 18 ASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSS 71 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 4/78 (5%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA----RNKDGRVGMIPV 175 ++ + E + + + +E L G++++I++K WW R K + G P Sbjct: 2 SSGSSGEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPA 61 Query: 176 PYVEKLVRSSPHGKHGNR 193 +V+ L SS + Sbjct: 62 SHVKLLGPSSERASGPSS 79 >1UUS-A nrPDB Length = 473 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 9/96 (9%) Query: 16 MGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLS---VSENSRVSHYIINSLPNRRFK 72 G + RQE LQ Q G F++R S PG + ++ V +R+ HY++ Sbjct: 355 YGYMGRQEVNDALQNQDPGTFIIRFSERNPGQFGIAYIGVEMPARIKHYLVQPND---TA 411 Query: 73 IGDQEFDHLPALLEFYK-IHYLDTTTLIEPAPRYPS 107 + F L E + ++ L T APR+ Sbjct: 412 AAKKTFPDF--LSEHSQFVNLLQWTKDTNGAPRFLK 445 >2VKN-A nrPDB Length = 70 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 1/41 (2%) Query: 141 DLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKL 181 ++ F++ EIL + E +WW AR +G G+IP YV+ + Sbjct: 23 EISFEQNEILQV-SDIEGRWWKARRANGETGIIPSNYVQLI 62 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Query: 255 ALALEVGDIVKVTRMNINGQWEGE-VNGRKGLFPFTHVKIFDPQNPDE 301 ++ E +I++V+ + W+ NG G+ P +V++ D P+E Sbjct: 23 EISFEQNEILQVSDIEGR-WWKARRANGETGIIPSNYVQLID--GPEE 67 >1J3T-A nrPDB Length = 74 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSP 186 + L + L F K +I+ ++E+ E WW GR G P YV+ + S Sbjct: 12 KAQALCSWTAKKDNHLNFSKHDIITVLEQQ-ENWWFGEVHGGR-GWFPKSYVKIIPGSES 69 Query: 187 HGKHG 191 G Sbjct: 70 GPSSG 74 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 250 AYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFD 295 A L DI+ V N W GEV+G +G FP ++VKI Sbjct: 21 AKKDNHLNFSKHDIITVLEQQEN-WWFGEVHGGRGWFPKSYVKIIP 65 >2ENM-A nrPDB Length = 77 Score = 48.6 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 127 YVRTLYDFPGND-AEDLPFKKGEILVIIE-KPEEQWWSARNKDGRVGMIPVPYVEKL 181 R +YDF +L +GEI+ + W +N G G++P YVE L Sbjct: 11 KARVMYDFAAEPGNNELTVTEGEIITVTNPNVGGGWLEGKNNKGEQGLVPTDYVEIL 67 Score = 40.9 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 2/49 (4%) Query: 254 TALALEVGDIVKVTRMNINGQW-EGEVN-GRKGLFPFTHVKIFDPQNPD 300 L + G+I+ VT N+ G W EG+ N G +GL P +V+I D Sbjct: 25 NELTVTEGEIITVTNPNVGGGWLEGKNNKGEQGLVPTDYVEILPNDGKD 73 >3PJP-A nrPDB Length = 199 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 23/175 (13%), Positives = 56/175 (32%), Gaps = 17/175 (9%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSR-VSHYIINSLP--- 67 +Y P + ++A+ L+ + G F++R SS ++ + H I L Sbjct: 10 HPYYF-PFNGKQAEDYLRSKERGDFVIRQSSRGDDHLAITWKLDKDLFQHVDIQELEKEN 68 Query: 68 ----NRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAED 123 + + Q + L ++ Y + + + ++ Sbjct: 69 PLALGKVLVVEGQRYHDLDQIIVEYLQNKIRLLNELTSNEKF--KAGTKKEVVKFIEDYS 126 Query: 124 NLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQW-WSARNKDGRVGMIPVPY 177 + +++Y F N F ++ + + + W+ + G V Y Sbjct: 127 KVNPKKSVYYFSLNYENPGWFY---LIFKLNAESKLYIWNVKLTH--TGFFLVNY 176 >2DMO-A nrPDB Length = 68 Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 120 TAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVE 179 ++ + E R L+ F E+L G I+ +++K + W + +G+ G++P Y+E Sbjct: 2 SSGSSGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNW-ATVMFNGQKGLVPCNYLE 60 Query: 180 KLVR 183 + Sbjct: 61 PVSG 64 Score = 34.0 bits (76), Expect = 0.091, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 20/47 (42%) Query: 246 RVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVK 292 K L + G+IV V + + NG+KGL P +++ Sbjct: 14 FGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 60 >2KYM-A nrPDB Length = 120 Score = 45.2 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKD--GRVGMIPVPYVEKLVRS 184 + TLY+F ++L GE L I + +W+ A+ + G G++PV YV + Sbjct: 5 FAVTLYEFKAERDDELDVSPGENLSICAHYDYEWFIAKPINRLGGPGLVPVSYVRIIDLM 64 Query: 185 SPH 187 P Sbjct: 65 DPA 67 >5VKO-A nrPDB Length = 211 Score = 44.8 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 62/181 (34%), Gaps = 29/181 (16%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSR-VSHYIINSLP--- 67 +Y P + ++A+ L+ + G F++R SS V++ + H I L Sbjct: 16 HPYYF-PFNGRQAEDYLRSKERGEFVIRQSSRGDDHLVITWKLDKDLFQHIDIQELEKEN 74 Query: 68 ----NRRFKIGDQEFDHLPALLEFY---KIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT 120 + + +Q+++ L ++ Y K+ L+ T E + Sbjct: 75 PLALGKVLIVDNQKYNDLDQIIVEYLQNKVRLLNEMTSSEKFKSGTKKDVVK-----FIE 129 Query: 121 AEDNLEYVRTLYDFPGNDAED----LPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVP 176 + +++Y F N L FK I + W+ + + G V Sbjct: 130 DYSRVNPNKSVYYFSLNHDNPGWFYLMFK------INANSKLYTWNVKLTN--TGYFLVN 181 Query: 177 Y 177 Y Sbjct: 182 Y 182 >1BB9-A nrPDB Length = 115 Score = 44.8 bits (104), Expect = 5e-05, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 38/85 (44%), Gaps = 14/85 (16%) Query: 111 GSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVII-----EKPEEQW----- 160 GS + L + V+ +D+ D ++L K G+++++I E+ +E W Sbjct: 30 GSTTTGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 89 Query: 161 ---WSARNKDGR-VGMIPVPYVEKL 181 W+ + + G+ P + E++ Sbjct: 90 ESDWNQHKELEKCRGVFPENFTERV 114 >3A98-A nrPDB Length = 184 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 41/108 (37%), Gaps = 11/108 (10%) Query: 111 GSVSAPNLPT--AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDG 168 GS + + D + +Y+F G+ A L + G+++ I ++ W+ Sbjct: 1 GSSGSSGMAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRI-QETCGDWYRGYLIKH 59 Query: 169 R--VGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTT 214 + G+ P ++ + + + N IP AQ TTT Sbjct: 60 KMLQGIFPKSFIH-IKEVTVEKRRNTENIIPAEIP-----LAQEVTTT 101 >1MV3-A nrPDB Length = 213 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 37/85 (43%), Gaps = 14/85 (16%) Query: 111 GSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVII-----EKPEEQW----- 160 G A L + V+ +D+ D ++L K G+++++I E+ +E W Sbjct: 128 GGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVK 187 Query: 161 ---WSARNKDGR-VGMIPVPYVEKL 181 W+ K + G+ P + E++ Sbjct: 188 ESDWNQHKKLEKCRGVFPENFTERV 212 Score = 34.4 bits (77), Expect = 0.069, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 42/148 (28%), Gaps = 24/148 (16%) Query: 172 MIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPA-------VSGSPG 224 +P V + + + + G EP A ++ LPA + + Sbjct: 66 FVPEISVTTPSQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGT 125 Query: 225 AAITPLPSTQNGP--VFAKAIQKRVPCAYDKTALALEVGDIVKVT-----RMNINGQWEG 277 + P K + A D L L+ GD+V V G G Sbjct: 126 VEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMG 185 Query: 278 ----------EVNGRKGLFPFTHVKIFD 295 ++ +G+FP + Sbjct: 186 VKESDWNQHKKLEKCRGVFPENFTERVP 213 >1VYT-A nrPDB Length = 351 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 59/186 (31%), Gaps = 27/186 (14%) Query: 92 YLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDN--LEYVRTLYDFPGNDAEDLP------ 143 LD+ +E + S + L A+ VRT + G E+ P Sbjct: 11 SLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGV 70 Query: 144 -FKKGEILVIIEKPEEQWWSARN--KDGRVGMIPVPYVEKLVRSSPHGKHGNRNSN-SYG 199 F+ + L I EK WW R + G + IP P ++L + R S Sbjct: 71 NFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSP--QRLESIRLKQEQKARRSGNPSS 128 Query: 200 IPEPA-----------HAYAQPQTTTPLPAVSG-SPGAAITP-LPSTQNGPVFAKAIQKR 246 + + Q + P V P + P L + + KA+ Sbjct: 129 LSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDF 188 Query: 247 VPCAYD 252 + +D Sbjct: 189 LKHRFD 194 >1MV0-B nrPDB Length = 81 Score = 43.2 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 33/69 (47%), Gaps = 14/69 (20%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVII-----EKPEEQW--------WSARNKDGR-VGM 172 V+ +D+ D ++L K G+++++I E+ +E W W+ K + G+ Sbjct: 12 KVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKKLEKCRGV 71 Query: 173 IPVPYVEKL 181 P + E++ Sbjct: 72 FPENFTERV 80 >2EL8-A nrPDB Length = 118 Score = 42.8 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 7/81 (8%) Query: 18 PVSRQEAQTRLQGQRH-GMFLVRDSSTCPGDYVLSVS--ENSR--VSHYIINSLPNRRFK 72 VSR EAQ L+ G L+R S ++ N V HY + + Sbjct: 27 KVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVI 86 Query: 73 IGDQEFD--HLPALLEFYKIH 91 +Q F L A++ ++ H Sbjct: 87 DVEQPFSCTSLDAVVNYFVSH 107 >4DEX-A nrPDB Length = 339 Score = 42.1 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 43/130 (33%), Gaps = 13/130 (10%) Query: 128 VRTLYDFPGNDAEDL-------PFKKGEILVIIEKPEEQWWSARNKDG--RVGMIPVPYV 178 VRT + +D+ F+ + L + EK WW R +G IP P Sbjct: 43 VRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPV- 101 Query: 179 EKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSG-SPGAAITP-LPSTQNG 236 KL + + + + + + + T P V P + P L + Sbjct: 102 -KLENMRLQHEQRAKEFKLHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVT 160 Query: 237 PVFAKAIQKR 246 + KA+ Sbjct: 161 DMMQKALFDF 170 >2RQR-A nrPDB Length = 119 Score = 41.3 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 26/60 (43%), Gaps = 3/60 (5%) Query: 123 DNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGR--VGMIPVPYVEK 180 D + +Y+F G+ A L + G+++ I ++ W+ + G+ P ++ Sbjct: 57 DKERHGVAIYNFQGSGAPQLSLQIGDVVRI-QETCGDWYRGYLIKHKMLQGIFPKSFIHI 115 >2RQW-A nrPDB Length = 105 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 2/68 (2%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSAR--NKDGRVGMIPVPYVEKLVRS 184 Y LYDF A++L GE L I +W+ A+ + G G++PV +V + + Sbjct: 4 YAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIA 63 Query: 185 SPHGKHGN 192 + + + Sbjct: 64 TGYATGND 71 >3GXW-A nrPDB Length = 103 Score = 40.5 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 33/88 (37%), Gaps = 9/88 (10%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSR-VSHYIINSLP--- 67 +Y P + ++A+ L+ + G F++R SS ++ + H I + Sbjct: 10 HPYYF-PFNGKQAEDYLRSKERGDFVIRQSSRGDDHLAITWKLDKDLFQHVDIQEMEKEN 68 Query: 68 ----NRRFKIGDQEFDHLPALLEFYKIH 91 + + Q + L ++ Y + Sbjct: 69 PLAMGKVLVVEGQRYHDLDQIIVEYLQN 96 >2CT4-A nrPDB Length = 70 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%), Gaps = 1/56 (1%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWW-SARNKDGRVGMIPVPYVEKLVR 183 +Y F G+ + +GE L ++E+ + W R K+G G +P Y+ Sbjct: 11 VAIYHFEGSSEGTISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYLRVTSG 66 >2CR4-A nrPDB Length = 126 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 10/98 (10%) Query: 4 ARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSV--SENSRVSHY 61 +S + + R E Q G++ +R+SST G VL V +++V +Y Sbjct: 22 NTTESCEVERLFKATSPRGEPQ-------DGLYCIRNSSTKSGK-VLVVWDETSNKVRNY 73 Query: 62 IINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLI 99 I ++ + G+ F + +++E Y H L + + Sbjct: 74 RIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSL 111 >2GTJ-A nrPDB Length = 96 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 21/53 (39%), Gaps = 2/53 (3%) Query: 140 EDLPFKKGEILVIIEKPE--EQWWSARNKDGRVGMIPVPYVEKLVRSSPHGKH 190 +L FK+GE + II + E W R G G I VE S K Sbjct: 42 NELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKD 94 >1VYV-A nrPDB Length = 359 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 33/102 (32%), Gaps = 11/102 (10%) Query: 86 EFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDN--LEYVRTLYDFPGNDAEDL- 142 + Y D+ +E +A L A+ V+T + G ED+ Sbjct: 4 DSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVP 63 Query: 143 ------PFKKGEILVIIEKPEEQWWSARNKDG--RVGMIPVP 176 F + L I EK WW R +G IP P Sbjct: 64 VPSSAVSFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSP 105 >1SPK-A nrPDB Length = 72 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 32/67 (47%), Gaps = 3/67 (4%) Query: 120 TAEDNLEYVRTLYDFP-GNDAEDLPFKKGEILVII-EKPEEQWWSARNKDGR-VGMIPVP 176 ++ + + V+T++ GN+ L F +G++L ++ + ++ W + + G P Sbjct: 2 SSGSSGQKVKTIFPHTAGNNKTLLSFAQGDVLTLLIPEEKDGWLYGEHDTTKARGWFPSS 61 Query: 177 YVEKLVR 183 Y + L Sbjct: 62 YTKLLSG 68 Score = 32.1 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 252 DKTALALEVGDIVKV-TRMNINGQWEGEVNGR--KGLFPFTHVKIF 294 +KT L+ GD++ + +G GE + +G FP ++ K+ Sbjct: 21 NKTLLSFAQGDVLTLLIPEEKDGWLYGEHDTTKARGWFPSSYTKLL 66 >1GCP-A nrPDB Length = 70 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 142 LPFKKGEILVIIEKPEE-QWWSARN-KDGRVGMIPVPYVEKLVR 183 L G+I+ + + E WW RN VG P V V Sbjct: 27 LRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVH 70 >1Y1U-A nrPDB Length = 585 Score = 39.0 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 22/47 (46%), Gaps = 4/47 (8%) Query: 14 WYMGPV----SRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENS 56 W G + ++Q+A L + G FL+R S + G ++ +S Sbjct: 462 WNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDS 508 >3RNJ-A nrPDB Length = 67 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 127 YVRTLYDFP-GNDAEDLPFKKGEILVIIEKPEEQWWS-ARNKDGR-VGMIPVPY 177 V+ ++ G+++ L FK+G+++ ++ W ++ + G P Y Sbjct: 9 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSY 62 Score = 37.8 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 23/47 (48%), Gaps = 3/47 (6%) Query: 252 DKTALALEVGDIVKVTRMNINGQW---EGEVNGRKGLFPFTHVKIFD 295 + T L+ + GD++ + W E E +G FPF++ ++ D Sbjct: 21 NSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLD 67 >1K1Z-A nrPDB Length = 78 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 142 LPFKKGEILVIIEKPEE-QWWSARN-KDGRVGMIPVPYVEKLVR 183 L G+I+ + + E WW RN VG P V V Sbjct: 35 LRLNPGDIVELTKAEAEHNWWEGRNTATNEVGWFPCNRVHPYVH 78 >2KXC-A nrPDB Length = 67 Score = 38.2 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 29/63 (46%), Gaps = 3/63 (4%) Query: 124 NLEYVRTLYDFP-GNDAEDLPFKKGEILVII-EKPEEQWWSARNKDGR-VGMIPVPYVEK 180 + V+T++ G++ L F +G+++ ++ + ++ W + + G P Y + Sbjct: 5 KKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKL 64 Query: 181 LVR 183 L Sbjct: 65 LEE 67 Score = 34.8 bits (78), Expect = 0.048, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 252 DKTALALEVGDIVKV-TRMNINGQWEGE--VNGRKGLFPFTHVKIFDP 296 +KT L+ GD++ + +G GE V+ +G FP ++ K+ + Sbjct: 20 NKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEE 67 >4ZW2-A nrPDB Length = 333 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 50/139 (35%), Gaps = 17/139 (12%) Query: 128 VRTLYDFPGNDAEDLP-------FKKGEILVIIEKPEEQWWSARNKDG--RVGMIPVPYV 178 VRT + + +++P F+ + L I EK WW R VG IP P V Sbjct: 42 VRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSP-V 100 Query: 179 EKLVRSSPH---GKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSG-SPGAAITP-LPST 233 + + +S+ +G P + + + P V P + P L Sbjct: 101 KLDSLRLLQEQTLRQNRLSSSKHGKRIPF--FKKTEHVPPYDVVPSMRPIILVGPSLKGY 158 Query: 234 QNGPVFAKAIQKRVPCAYD 252 + + KA+ + +D Sbjct: 159 EVTDMMQKALFDFLKHRFD 177 >3MAZ-A nrPDB Length = 125 Score = 37.1 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 39/90 (43%), Gaps = 9/90 (10%) Query: 6 FDSSDRSAWYMGPVSRQEAQTRLQGQR-HGMFLVRDSSTCPGDYVLSVSENS---RVSHY 61 D + VSR+EA LQ G ++R S +Y +++ + R+ HY Sbjct: 9 VDVLNPMPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSR-NYSITIRQEIDIPRIKHY 67 Query: 62 IINSLPNRRFKIGDQEFDHLPAL---LEFY 88 + S+ + I ++ LP L ++++ Sbjct: 68 KVMSVGQN-YTIELEKPVTLPNLFSVIDYF 96 >4Y5W-A nrPDB Length = 549 Score = 36.7 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 37/132 (28%), Gaps = 19/132 (14%) Query: 17 GPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENS-----RVSHYIINSLPNRRF 71 G +S+Q + L + G FL+R S + G ++ ++ + S + Sbjct: 431 GFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSI 490 Query: 72 KIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTL 131 + L L Y P+ P +D YV Sbjct: 491 RSLGDRIRDLAQLKNLY--------------PKKPKDEAFRSHYKPEQMGKDGRGYVPAT 536 Query: 132 YDFPGNDAEDLP 143 + LP Sbjct: 537 IKMTVERDQPLP 548 >1T0J-A nrPDB Length = 132 Score = 36.7 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 32/102 (31%), Gaps = 11/102 (10%) Query: 86 EFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDN--LEYVRTLYDFPGNDAEDL- 142 + Y D+ +E + L A+ VRT + +D+ Sbjct: 7 DSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVP 66 Query: 143 ------PFKKGEILVIIEKPEEQWWSARNKDG--RVGMIPVP 176 F+ + L + EK WW R +G IP P Sbjct: 67 VPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSP 108 >1U3O-A nrPDB Length = 82 Score = 35.5 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 30/73 (41%), Gaps = 6/73 (8%) Query: 109 PMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEE--QWWSARN- 165 P+GS P + E L DF + +L + G+ + ++E+P E W R Sbjct: 2 PLGSPGIPGSTLSGG-CELTVVLQDFSAAHSSELSIQVGQTVELLERPSERPGWCLVRTT 60 Query: 166 --KDGRVGMIPVP 176 + G++P Sbjct: 61 ERSPPQEGLVPSS 73 >2DE0-X nrPDB Length = 526 Score = 35.5 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 122 EDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KDGRVGMIPV 175 N +Y A+++P + G+I+ + + + N K GR G+ P Sbjct: 439 GQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPS 493 >2CUD-A nrPDB Length = 79 Score = 35.5 bits (80), Expect = 0.027, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Query: 111 GSVSAPNLPTAEDNLE--YVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARN-KD 167 GS + + L+ ++ L D+P D F++GE L +I WW A + Sbjct: 1 GSSGSSGPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEG-GWWKAISLST 59 Query: 168 GRVGMIPVPYVEKLVR 183 GR IP V ++ Sbjct: 60 GRESYIPGICVARVSG 75 >5F3Y-A nrPDB Length = 621 Score = 35.5 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 6/54 (11%) Query: 127 YVRTLYDFPGNDA-EDLPFKKGEILVIIEKPE----EQWWSARNK-DGRVGMIP 174 + L D D LPFKKG++L++ +K E W +N G+ G++P Sbjct: 545 FAMALQDRRATDDITLLPFKKGDLLILTKKQGLLASENWALGQNDRTGKTGLVP 598 >4HZS-A nrPDB Length = 341 Score = 35.1 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 25/56 (44%), Gaps = 6/56 (10%) Query: 129 RTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRV---GMIPVPYVEKL 181 R L DF + + L + +++ +IE E +W R ++ R G P V + Sbjct: 282 RALQDFE--EPDKLHIQMNDVITVIEGRAENYWW-RGQNTRTLCVGPFPRNVVTSV 334 >5GJW-B nrPDB Length = 106 Score = 34.4 bits (77), Expect = 0.072, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 9/58 (15%) Query: 128 VRTLYDFPGNDAEDLP-------FKKGEILVIIEKPEEQWWSARNKDG--RVGMIPVP 176 VRT + + +++P F+ + L I EK WW R VG IP P Sbjct: 37 VRTNVGYNPSPGDEVPVEGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSP 94 >3TSW-A nrPDB Length = 391 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 46/150 (30%), Gaps = 30/150 (20%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEK----PEEQWWSAR----NKDGRVGMIP-VPY 177 Y+RT +++ L F KGE+ +++ W + R +K+ G+IP Sbjct: 108 YIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNR 167 Query: 178 VEKLVR---SSPHGKHGN----------RNSNSYGIPEPAHAYAQP--------QTTTPL 216 E+L + P G+ R+S AQP + Sbjct: 168 AEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLR 227 Query: 217 PAVSGSPGAAITPLPSTQNGPVFAKAIQKR 246 A P P+ + + Sbjct: 228 EAGFLRPVTIFGPIADVAREKLAREEPDIY 257 >3LH5-A nrPDB Length = 251 Score = 32.8 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 19/128 (14%), Positives = 37/128 (28%), Gaps = 23/128 (17%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEK----PEEQWWSAR----NKDGRVGMIPVPYV 178 Y+RT +++ L F KGE+ +++ W + R +K+ G+IP Sbjct: 5 YIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNK-- 62 Query: 179 EKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPV 238 NR + + + A P P+ + Sbjct: 63 -------------NRAEQLASVQYVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKL 109 Query: 239 FAKAIQKR 246 + Sbjct: 110 AREEPDIY 117 >3SHW-A nrPDB Length = 468 Score = 32.4 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 26/150 (17%), Positives = 46/150 (30%), Gaps = 30/150 (20%) Query: 127 YVRTLYDFPGNDAEDLPFKKGEILVIIEK----PEEQWWSAR----NKDGRVGMIP-VPY 177 Y+RT +++ L F KGE+ +++ W + R +K+ G+IP Sbjct: 100 YIRTHFEYEKESPYGLSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGIIPNKNR 159 Query: 178 VEKLVR---SSPHGKHGN----------RNSNSYGIPEPAHAYAQP--------QTTTPL 216 E+L + P G+ R+S AQP + Sbjct: 160 AEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAYERVVLR 219 Query: 217 PAVSGSPGAAITPLPSTQNGPVFAKAIQKR 246 A P P+ + + Sbjct: 220 EAGFLRPVTIFGPIADVAREKLAREEPDIY 249 >4E68-A nrPDB Length = 596 Score = 32.1 bits (71), Expect = 0.32, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 50/150 (33%), Gaps = 11/150 (7%) Query: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCP-GDYVLSVSENSRVSHYIINSLPNRR 70 + MG +S++ + L + G FL+R S + G + E I S+ Sbjct: 456 EGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGSTQIQSVEP-- 513 Query: 71 FKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRT 130 + ++ YKI D T ++ Y P + A ++ E+ Sbjct: 514 YTKQQLNNMSFAEIIMGYKIM--DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEA 571 Query: 131 LYDFPGNDAEDLPFKKGEILVIIEKPEEQW 160 + P+ K + + + + W Sbjct: 572 ------DPGSAAPYLKTKFICVTPFIDAVW 595 >1E5Q-A nrPDB Length = 450 Score = 32.1 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 18/141 (12%), Positives = 42/141 (29%), Gaps = 12/141 (8%) Query: 107 SPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNK 166 + + + + + L E + F++GE +++ + + + NK Sbjct: 313 KRIVAGLKWLGIFSDKKITPRGNALDTLCATLEEKMQFEEGERDLVMLQHK---FEIENK 369 Query: 167 DGRVGMIPVPYVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAA 226 DG L G ++ + A + + S Sbjct: 370 DGSR----ETRTSSLCEYGAPIGSGGYSAMA---KLVGVPCAVAVKF--VLDGTISDRGV 420 Query: 227 ITPLPSTQNGPVFAKAIQKRV 247 + P+ S N P+ + +K Sbjct: 421 LAPMNSKINDPLMKELKEKYG 441 >1BF5-A nrPDB Length = 575 Score = 31.3 bits (69), Expect = 0.47, Method: Composition-based stats. Identities = 22/136 (16%), Positives = 44/136 (32%), Gaps = 22/136 (16%) Query: 17 GPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNRRFKIGDQ 76 G +S++ + L+ Q+ G FL+R S + ++ + N G+ Sbjct: 445 GFISKERERALLKDQQPGTFLLRFSESSR---------EGAITFTWVERSQNG----GEP 491 Query: 77 EFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDF-- 134 +F +E Y L T + Y ++ L N++ + Sbjct: 492 DFHA----VEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYS 547 Query: 135 ---PGNDAEDLPFKKG 147 + +L KG Sbjct: 548 RPKEAPEPMELDGPKG 563 >3HZG-A nrPDB Length = 258 Score = 31.3 bits (69), Expect = 0.56, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 22/84 (26%), Gaps = 2/84 (2%) Query: 52 VSENSRVSHYIINSLPNRRFKIGDQEFDHLPALL--EFYKIHYLDTTTLIEPAPRYPSPP 109 + V H+ + + F I L+ + L + E R PP Sbjct: 61 LRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPP 120 Query: 110 MGSVSAPNLPTAEDNLEYVRTLYD 133 A + + R Y Sbjct: 121 GMEDDADLRHILTEAADAARATYS 144 >6GME-A nrPDB Length = 201 Score = 30.9 bits (68), Expect = 0.79, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 31/82 (37%), Gaps = 12/82 (14%) Query: 19 VSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSV---SENSRVSHYIINSLP-------N 68 ++ ++A+ ++ G ++R SS G+ L+V + H + Sbjct: 19 INFKQAEKMMETMDQGDVIIRPSSK--GENHLTVTWKVSDGIYQHVDVREEGKENAFSLG 76 Query: 69 RRFKIGDQEFDHLPALLEFYKI 90 I +EF+ L ++ Y Sbjct: 77 ATLWINSEEFEDLDEIVARYVQ 98 >1YVL-A nrPDB Length = 683 Score = 30.1 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 17/28 (60%) Query: 17 GPVSRQEAQTRLQGQRHGMFLVRDSSTC 44 G +S++ + L+ Q+ G FL+R S + Sbjct: 580 GFISKERERALLKDQQPGTFLLRFSESS 607 >2DIA-A nrPDB Length = 113 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 18/44 (40%), Gaps = 1/44 (2%) Query: 20 SRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSR-VSHYI 62 S +A+ +Q + G + V G Y L++ V H+ Sbjct: 52 SGTKAEVSIQNNKDGTYAVTYVPLTAGMYTLTMKYGGELVPHFP 95 >6DLH-A nrPDB Length = 734 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 21/61 (34%), Gaps = 11/61 (18%) Query: 100 EPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ 159 + P + S PM A L L+ YDF +G++L I + Sbjct: 527 DGTPVWFSNPMVLAKATALKDYGSLLKLGVDFYDF-----------EGDVLTITKTSGPD 575 Query: 160 W 160 W Sbjct: 576 W 576 >6DNS-A nrPDB Length = 623 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 21/61 (34%), Gaps = 11/61 (18%) Query: 100 EPAPRYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQ 159 + P + S PM A L L+ YDF +G++L I + Sbjct: 527 DGTPVWFSNPMVLAKATALKDYGSLLKLGVDFYDF-----------EGDVLTITKTSGPD 575 Query: 160 W 160 W Sbjct: 576 W 576 >4FK8-A nrPDB Length = 271 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 40/127 (31%), Gaps = 14/127 (11%) Query: 130 TLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPHGK 189 TL+ F + L F GE ++ + + + ++ Y E L S + Sbjct: 33 TLFSFTCTRDQALRFNNGEFTMVGLEVD-----GKPLTRAYSIVSPNYEEHLEFFSIKVQ 87 Query: 190 HGNRNS--NSYGIPEPAHAYAQPQTTTPLPAVSG-------SPGAAITPLPSTQNGPVFA 240 +G S + +P +P T + S G + P S P Sbjct: 88 NGPLTSRLQHLKVGDPVLIGKKPTGTLVADNLLPGKTLWMLSTGTGLAPFMSIIRDPDIY 147 Query: 241 KAIQKRV 247 + K V Sbjct: 148 ERFDKVV 154 >1J9A-A nrPDB Length = 184 Score = 29.4 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 68 NRRFKIGDQEF--DHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPTAEDNL 125 D+ F ++P L +++ +LD +TL E A R+ + N A D++ Sbjct: 107 CGNSIAQDKRFLVKYMPDLADYFHYRHLDVSTLKELAARWKPEILEGFKKENTHLALDDI 166 Query: 126 E 126 Sbjct: 167 R 167 >5JU6-A nrPDB Length = 857 Score = 29.0 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%), Gaps = 1/61 (1%) Query: 188 GKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFAKAIQKRV 247 + + S+G P A P +P + P T L ++ N P + +K V Sbjct: 670 ASGFTKAAQSFGQPSNASDNLYPSDIERVP-LYIYPWLNSTDLKASANDPDYGLPTEKYV 728 Query: 248 P 248 P Sbjct: 729 P 729 >2AAN-A nrPDB Length = 139 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 16/37 (43%) Query: 237 PVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNING 273 PV + K A+DKT L + G V + N + Sbjct: 18 PVTIEIGSKGEELAFDKTELTVSAGQTVTIRFKNNSA 54 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.125 0.326 Lambda K H 0.267 0.0378 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,152,755 Number of Sequences: 36641 Number of extensions: 437270 Number of successful extensions: 1489 Number of sequences better than 10.0: 167 Number of HSP's better than 10.0 without gapping: 242 Number of HSP's successfully gapped in prelim test: 57 Number of HSP's that attempted gapping in prelim test: 859 Number of HSP's gapped (non-prelim): 458 length of query: 303 length of database: 10,336,785 effective HSP length: 97 effective length of query: 206 effective length of database: 6,782,608 effective search space: 1397217248 effective search space used: 1397217248 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 58 (27.1 bits)