BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P45974 (858 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3IHP-A nrPDB 1690 0.0 2G45-A nrPDB 279 3e-75 2L80-A nrPDB 189 5e-48 2GFO-A nrPDB 84 3e-16 6CPM-C nrPDB 70 3e-12 2Y6E-A nrPDB 67 2e-11 4FIP-A nrPDB 67 2e-11 3MTN-A nrPDB 54 4e-07 6DGF-A nrPDB 52 1e-06 5L8W-A nrPDB 50 4e-06 5K1A-A nrPDB 48 2e-05 5L8H-A nrPDB 47 4e-05 5GJQ-x nrPDB 42 0.001 1WGN-A nrPDB 42 0.001 4AE4-A nrPDB 42 0.001 2AYN-A nrPDB 42 0.001 5CHV-A nrPDB 40 0.003 3JCR-V nrPDB 40 0.005 6H4H-A nrPDB 40 0.005 1OQY-A nrPDB 40 0.006 6HEH-A nrPDB 40 0.006 1VJV-A nrPDB 39 0.010 5MPC-8 nrPDB 39 0.010 5WCH-A nrPDB 38 0.015 5TXK-A nrPDB 37 0.027 5O71-A nrPDB 37 0.037 6H4J-A nrPDB 37 0.039 5G0F-A nrPDB 37 0.041 2F1Z-A nrPDB 37 0.043 5JTV-A nrPDB 37 0.045 5JTJ-A nrPDB 37 0.054 5J7T-A nrPDB 37 0.054 3C5K-A nrPDB 35 0.11 5GVI-A nrPDB 35 0.19 5OHK-A nrPDB 34 0.26 5OHN-A nrPDB 34 0.27 6HOZ-A nrPDB 31 2.5 5EZ1-A nrPDB 30 5.1 >3IHP-A nrPDB Length = 854 Score = 1690 bits (4376), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/858 (97%), Positives = 835/858 (97%), Gaps = 23/858 (2%) Query: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 60 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER Sbjct: 20 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 79 Query: 61 HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 120 HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV Sbjct: 80 HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 139 Query: 121 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 180 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA Sbjct: 140 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 199 Query: 181 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 240 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET Sbjct: 200 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 259 Query: 241 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 300 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM Sbjct: 260 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 319 Query: 301 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 360 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK Sbjct: 320 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 379 Query: 361 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 420 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL Sbjct: 380 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 439 Query: 421 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 480 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT Sbjct: 440 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 499 Query: 481 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 540 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE Sbjct: 500 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 559 Query: 541 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS Sbjct: 560 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 619 Query: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI 660 QLRGTGLQPGEEELPDIAPPLVTPDEPK +PMLDESVI Sbjct: 620 QLRGTGLQPGEEELPDIAPPLVTPDEPK-----------------------APMLDESVI 656 Query: 661 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 720 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA Sbjct: 657 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 716 Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 780 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA Sbjct: 717 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 776 Query: 781 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 840 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS Sbjct: 777 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 836 Query: 841 EKPPKDLGYIYFYQRVAS 858 EKPPKDLGYIYFYQRVAS Sbjct: 837 EKPPKDLGYIYFYQRVAS 854 >2G45-A nrPDB Length = 129 Score = 279 bits (714), Expect = 3e-75, Method: Compositional matrix adjust. Identities = 129/129 (100%), Positives = 129/129 (100%) Query: 163 KQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR 222 KQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR Sbjct: 1 KQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR 60 Query: 223 YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGID 282 YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGID Sbjct: 61 YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGID 120 Query: 283 MLKMQKTDK 291 MLKMQKTDK Sbjct: 121 MLKMQKTDK 129 >2L80-A nrPDB Length = 116 Score = 189 bits (479), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 84/115 (73%), Positives = 99/115 (86%) Query: 175 QVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAV 234 VSK+A +L QLDN RIPP GWKC++CD+RENLWLNLTDGS+LCG+ +FD SGGN HA+ Sbjct: 2 SVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHAL 61 Query: 235 EHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKT 289 EHYR+ GYPLAVKLGTITPDGADVYS+ E++ VLDP LA+HL+HFGIDML M T Sbjct: 62 EHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGT 116 >2GFO-A nrPDB Length = 396 Score = 83.6 bits (205), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 77/299 (25%), Positives = 137/299 (45%), Gaps = 38/299 (12%) Query: 317 LKPLFG---PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDF 373 L P+FG P TG+RNLGN+CY+NS++Q L + P Y ++ + QD Sbjct: 51 LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA-DYFNR----------NCYQDD 99 Query: 374 STQVAKLGH-GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNR 432 + LGH G ++ E+ + G+ I+P+ FK IGK + +F+ Sbjct: 100 INRSNLLGHKGEVAEEFGIIMKALWTGQ--------YRYISPKDFKITIGKINDQFAGYS 151 Query: 433 QQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEK-----IKCLATEKVKYTQRVDYIM 487 QQD+QE L L++ + + ++N R+ E K K+ Q + I+ Sbjct: 152 QQDSQELLLFLMDGLHEDLNKADNRK---RYKEENNDHLDDFKAAEHAWQKHKQLNESII 208 Query: 488 QLPVPMDAALNKEELLEYEEKKRQAEE-EKMALPELVRAQVPFSSCLEAYGAPEQVDD-- 544 + + + + L +K R E ++LP ++ CL + E++ D Sbjct: 209 -VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNN 267 Query: 545 -FWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQ 601 F+ + +A+ ++K P L++ +K+F++ W +KL S++ P E LD+SQ Sbjct: 268 RFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 325 >6CPM-C nrPDB Length = 349 Score = 70.5 bits (171), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 73/294 (24%), Positives = 129/294 (43%), Gaps = 37/294 (12%) Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYV-DKL-EKIFQNAPTDPTQDFSTQVAKL 380 PG G+ NLGN+C++NS +Q L + P ++ DK E++ + P + + A+L Sbjct: 17 PGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAEL 76 Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440 + SG++S + PR FK +G+ P+FS +QQD QE Sbjct: 77 IKQMWSGKFSY--------------------VTPRAFKTQVGRFAPQFSGYQQQDCQELL 116 Query: 441 LHLINMVERNC-RSSENPNEVFRFLVEEKIKCLATEKVK-YTQRVDYIMQLPVPMDAALN 498 L++ + + R + P + K +A E + + +R D I+ V + L Sbjct: 117 AFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSII---VDIFHGLF 173 Query: 499 KEELLEYEEKKRQAEEE-----KMALPELVRAQVPFSSCLEAYGAPEQV---DDFWSTAL 550 K L+ E K + + LP + V C+E + E++ D ++ Sbjct: 174 KSTLVCPECAKISVTFDPFCYLTLPLPMPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNC 233 Query: 551 QAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQLR 603 + A K S P LV+ +K+F++ ++ KLD ++ P +LD+S R Sbjct: 234 KEHQQATKKLDLWSLPPVLVVHLKRFSYS-RYMRDKLDTLVDFPINDLDMSGCR 286 >2Y6E-A nrPDB Length = 367 Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 71/310 (22%), Positives = 120/310 (38%), Gaps = 73/310 (23%) Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYV-DKLE-KIFQNAPTDPTQDFSTQVAKL 380 PG G+ NLGN+C++NS +Q L + ++ D+ E +I ++ P + + A+L Sbjct: 6 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 65 Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440 + SG + +APRMFK +G+ P+FS +QQD+QE Sbjct: 66 IKQMWSGRDAH--------------------VAPRMFKTQVGRFAPQFSGYQQQDSQELL 105 Query: 441 LHLINMVERNC-RSSENPN-------------------------------EVFRFLVEEK 468 L++ + + R + P + F L + Sbjct: 106 AFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKST 165 Query: 469 IKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPE-LVRAQV 527 + C KV T + LP+P+ KK + E M P+ + V Sbjct: 166 LVCPECAKVSVTFDPFCYLTLPLPL--------------KKDRVMEGPMLQPQKKKKTTV 211 Query: 528 PFSSCLEAYGAPEQV---DDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVP 584 C+E + E + D ++ + A K S P LV+ +K+F++ W Sbjct: 212 ALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYW-R 270 Query: 585 KKLDVSIEMP 594 KLD +E P Sbjct: 271 DKLDTVVEFP 280 >4FIP-A nrPDB Length = 476 Score = 67.4 bits (163), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 78/331 (23%), Positives = 128/331 (38%), Gaps = 63/331 (19%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPT-DPTQDFSTQVAKLGH 382 G +G+ N+GN+C+++S++Q L P F R + ++ N P + FS + K+ H Sbjct: 140 GLSGLINMGNTCFMSSILQCLIHNPYFIRHSMSQIHS--NNCKVRSPDKCFSCALDKIVH 197 Query: 383 GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLH 442 L +K S Q G + A K + + QQDA EF+ Sbjct: 198 ELYGALNTKQASSSSTSTN------RQTGFIYLLTCAW--KINQNLAGYSQQDAHEFWQF 249 Query: 443 LINMVER-------NCRSSENPNE---------VFRFLVEEKIKCLATEKVKYTQRVDYI 486 +IN + + N + N VF +E I C + T +D Sbjct: 250 IINQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT-TIDPF 308 Query: 487 MQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFW 546 + L L+ ++KK+ E CL+++ EQ+ DF Sbjct: 309 LDLS------------LDIKDKKKLYE------------------CLDSFHKKEQLKDFN 338 Query: 547 STALQAKSV--AVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRG 604 + S A+K P LV+Q+K+F L+ +KLD IE P L++ Sbjct: 339 YHCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCS 398 Query: 605 TGLQPGEEE---LPDIAPPLVTPDEPKGSLG 632 T + E +PDI L+ KG++ Sbjct: 399 TKEKDKHSENGKVPDIIYELIGIVSHKGTVN 429 >3MTN-A nrPDB Length = 373 Score = 53.5 bits (127), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 40/138 (28%), Positives = 58/138 (42%), Gaps = 40/138 (28%) Query: 317 LKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQ 376 L P G+ G+RNLGN+C+LN+V+Q L S T P +DF Sbjct: 14 LVPRGSSGHVGLRNLGNTCFLNAVLQCLSS--------------------TRPLRDFC-- 51 Query: 377 VAKLGHGLLSGEYSKPVPESGDGERVPE----------QKEVQDGIAPRMFKALIGKGHP 426 L ++ + VP G + + E + + + P F+A+ K P Sbjct: 52 --------LRRDFRQEVPGGGRAQELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVP 103 Query: 427 EFSTNRQQDAQEFFLHLI 444 FS QQDAQEF L+ Sbjct: 104 SFSGYSQQDAQEFLKLLM 121 Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust. Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 7/121 (5%) Query: 739 DQALKALRATNN-SLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDG 797 D+ + R+T +++R + H++ A I + D + + +G D Sbjct: 249 DRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG-SIKKSSVGVDFPLQRLSLGDFASDK 307 Query: 798 PGK--YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--CASEKPPKDLGYIYFY 853 G YQL+A +H G S GHY + + W +YND +V + + GY+ FY Sbjct: 308 AGSPVYQLYALCNHSG-SVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFY 366 Query: 854 Q 854 Q Sbjct: 367 Q 367 >6DGF-A nrPDB Length = 370 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 48/166 (28%), Positives = 73/166 (43%), Gaps = 27/166 (16%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 G G+RNLGN+C++NS++Q L + + R Y L++++ + L HG Sbjct: 30 GLAGLRNLGNTCFMNSILQCLSNTREL-RDYC--LQRLY--------------MRDLHHG 72 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 S ++ V E + D ++P FK I + P F QQDAQEF L Sbjct: 73 --SNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFL 130 Query: 444 I----NMVER-NCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484 + N V R R NP + +EK + + KY +R D Sbjct: 131 LDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWR---KYLERED 173 Score = 35.4 bits (80), Expect = 0.094, Method: Compositional matrix adjust. Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 801 YQLFAFISHMGTSTMCGHYV--CHIKKEGRWVIYNDQKVC--ASEKPPKDLGYIYFYQ 854 Y L+A +H GT TM GHY C G W +ND V +S + Y+ FY+ Sbjct: 306 YNLYAVSNHSGT-TMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 362 >5L8W-A nrPDB Length = 376 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 62/293 (21%), Positives = 106/293 (36%), Gaps = 42/293 (14%) Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384 Y G+ N GN+CY NSV+Q L+ F+ K + +++ P + T +A L H Sbjct: 44 YFGLVNFGNTCYCNSVLQALYFCRPFREKVL-----AYKSQPRKK-ESLLTCLADLFHS- 96 Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444 + QK+ I P+ F + K + F QQDA EF +L+ Sbjct: 97 -----------------IATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLL 139 Query: 445 NMVE---RNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 N + + R E N + +T + + L E Sbjct: 140 NTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEI---------FQGTLTNET 190 Query: 502 LLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD---FWSTALQAKSVAVK 558 E +E+ + L V + CL + E + ++ ++K A K Sbjct: 191 RCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHK 250 Query: 559 TTRFASFPDYLVIQIKKFTFGLDWVPK--KLDVSIEMPEELDISQLRGTGLQP 609 + P L + +K+F + +D + + KL + P EL + G P Sbjct: 251 RMKVKKLPMILALHLKRFKY-MDQLHRYTKLSYRVVFPLELRLFNTSGDATNP 302 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 14/68 (20%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--------------CASEKPPKD 846 Y L A + H G+ GHY+ +K W++++D V + + Sbjct: 306 YDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSE 365 Query: 847 LGYIYFYQ 854 GYI FYQ Sbjct: 366 SGYILFYQ 373 >5K1A-A nrPDB Length = 331 Score = 48.1 bits (113), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/291 (20%), Positives = 105/291 (36%), Gaps = 42/291 (14%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ N GN+CY NSV+Q L+ F+ K + +++ P + T +A L H Sbjct: 1 GLVNFGNTCYCNSVLQALYFCRPFREKVL-----AYKSQPRKK-ESLLTCLADLFHS--- 51 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINM 446 + QK+ I P+ F + K + F QQDA EF +L+N Sbjct: 52 ---------------IATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNT 96 Query: 447 VE---RNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL 503 + + R E N + +T + + L E Sbjct: 97 IADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEI---------FQGTLTNETRC 147 Query: 504 EYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDD---FWSTALQAKSVAVKTT 560 E +E+ + L V + CL + E + ++ ++K A K Sbjct: 148 LTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRM 207 Query: 561 RFASFPDYLVIQIKKFTFGLDWVPK--KLDVSIEMPEELDISQLRGTGLQP 609 + P L + +K+F + +D + + KL + P EL + G P Sbjct: 208 KVKKLPMILALHLKRFKY-MDQLHRYTKLSYRVVFPLELRLFNTSGDATNP 257 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 28/68 (41%), Gaps = 14/68 (20%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--------------CASEKPPKD 846 Y L A + H G+ GHY+ +K W++++D V + + Sbjct: 261 YDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSE 320 Query: 847 LGYIYFYQ 854 GYI FYQ Sbjct: 321 SGYILFYQ 328 >5L8H-A nrPDB Length = 359 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 24/123 (19%) Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384 Y G+ N GN+CY+NSV+Q L+ F R + + + + A ++ T +A L H Sbjct: 27 YFGLVNFGNTCYVNSVLQALY----FCRPFRENV--LAYKAQQKKKENLLTCLADLFHS- 79 Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444 + QK+ I P+ F + + K + F QQDA EF +L+ Sbjct: 80 -----------------IATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 122 Query: 445 NMV 447 N + Sbjct: 123 NTI 125 Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 14/68 (20%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--------------CASEKPPKD 846 Y L A + H G+ GHY+ +K G W++++D V + + Sbjct: 289 YDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSE 348 Query: 847 LGYIYFYQ 854 GYI FYQ Sbjct: 349 SGYILFYQ 356 >5GJQ-x nrPDB Length = 494 Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust. Identities = 55/299 (18%), Positives = 120/299 (40%), Gaps = 57/299 (19%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ NLGN+CY+N+ VQ + S+P+ + D + ++ + G + S Sbjct: 106 GLTNLGNTCYMNATVQCIRSVPELK----------------DALKRYAGALRASGE-MAS 148 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTN------RQQDAQEFF 440 +Y + + + I P + + P+F+ QQDA E + Sbjct: 149 AQYIT----AALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECW 204 Query: 441 LHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKE 500 + ++ ++++K++ + + VK T P + +++ Sbjct: 205 IQMMR------------------VLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQF 246 Query: 501 ELLEY----------EEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTAL 550 +E+ EE+ + +E ++ L + +V + E++ S L Sbjct: 247 FGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK-QSPTL 305 Query: 551 QAKSVAVKTTRFASFPDYLVIQIKKFTFG-LDWVPKKLDVSIEMPEELDISQLRGTGLQ 608 Q ++ +K+++ + P YL IQ+ +F + + V K+ ++ P LD+ +L LQ Sbjct: 306 QRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQ 364 Score = 38.9 bits (89), Expect = 0.010, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 799 GKYQLFAFISHMGTSTMCGHYVCHIK-KEGRWVIYNDQKV 837 G Y L A ++H G S+ GHYV +K K+ W+ ++D KV Sbjct: 416 GYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKV 455 >1WGN-A nrPDB Length = 63 Score = 42.4 bits (98), Expect = 0.001, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 28/42 (66%) Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSH 762 P CV T+V+MG+S + L+A++ ++E+ +D++F+H Sbjct: 16 SPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAH 57 >4AE4-A nrPDB Length = 118 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 37/62 (59%), Gaps = 7/62 (11%) Query: 722 PPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSH-------IDDLDAEAAMDI 774 P CV T+V+MG+S + L+A++A ++E+ +D++F+H D L E A+++ Sbjct: 6 PSERQCVETVVNMGYSYECVLRAMKAAGANIEQILDYLFAHGQLCEKGFDPLLVEEALEM 65 Query: 775 SE 776 + Sbjct: 66 HQ 67 >2AYN-A nrPDB Length = 404 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 55/299 (18%), Positives = 119/299 (39%), Gaps = 57/299 (19%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ NLGN+CY+N+ VQ + S+P+ + D + ++ + G + S Sbjct: 16 GLTNLGNTCYMNATVQCIRSVPELK----------------DALKRYAGALRASGE-MAS 58 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTN------RQQDAQEFF 440 +Y + + I P + + P+F+ QQDA E + Sbjct: 59 AQYITAALR----DLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECW 114 Query: 441 LHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKE 500 + ++ ++++K++ + + VK T P + +++ Sbjct: 115 IQMMR------------------VLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQF 156 Query: 501 ELLEY----------EEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTAL 550 +E+ EE+ + +E ++ L + +V + E++ S L Sbjct: 157 FGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK-QSPTL 215 Query: 551 QAKSVAVKTTRFASFPDYLVIQIKKFTFG-LDWVPKKLDVSIEMPEELDISQLRGTGLQ 608 Q ++ +K+++ + P YL IQ+ +F + + V K+ ++ P LD+ +L LQ Sbjct: 216 QRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQ 274 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%) Query: 799 GKYQLFAFISHMGTSTMCGHYVCHIK-KEGRWVIYNDQKV 837 G Y L A ++H G S+ GHYV +K K+ W+ ++D KV Sbjct: 326 GYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKV 365 >5CHV-A nrPDB Length = 323 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 26/40 (65%), Gaps = 3/40 (7%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIKK--EGRWVIYNDQKVC 838 Y+LFA I+H+G + GHY +I+ +G+W +ND VC Sbjct: 253 YELFAVIAHVGMADF-GHYCAYIRNPVDGKWFCFNDSHVC 291 Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust. Identities = 63/330 (19%), Positives = 111/330 (33%), Gaps = 71/330 (21%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 G G+ N+G +C LNS++QV DF ++ T P Sbjct: 5 GLVGLHNIGQTCCLNSLLQVFMMNMDF---------RMILKRITVPRS------------ 43 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAP-RMFKALIGKGHPEFSTNRQQDAQEFFLH 442 + E + VP Q Q + P + + L P F Q DA + +L Sbjct: 44 --AEERKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFV---QHDAAQLYLT 98 Query: 443 LINMVERNCRS---SENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNK 499 + N+ + +E +F +E + C+ Sbjct: 99 IWNLTKDQITDTDLTERLQGLFTIWTQESLICVGCTA----------------------- 135 Query: 500 EELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKT 559 E R+++ ++LP + P + +A Q + S+ + +S KT Sbjct: 136 -------ESSRRSKLLTLSLPLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKT 188 Query: 560 -----TRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGEEEL 614 + P L I + +F+ + +K+ S+ P+ LD SQ+ P EE+L Sbjct: 189 PWKQVLKLTHLPQTLTIHLMRFS-ARNSRTEKICHSVNFPQSLDFSQVL-----PTEEDL 242 Query: 615 PDIAPPLVTPDEPKGSLGFYGNEDEDSFCS 644 D E + G D +C+ Sbjct: 243 GDTKEQSEIHYELFAVIAHVGMADFGHYCA 272 >3JCR-V nrPDB Length = 565 Score = 40.0 bits (92), Expect = 0.005, Method: Compositional matrix adjust. Identities = 75/379 (19%), Positives = 152/379 (40%), Gaps = 71/379 (18%) Query: 215 GSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAE 274 ++CG+ YF G G +HA H + + + + L T+ Y ++ ++D SL E Sbjct: 135 ACLVCGK-YFQGRGLKSHAYIHSVQFSHHVFLNLHTL-----KFYCLPDNYEIIDSSL-E 187 Query: 275 HLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNS 334 +++ +LK T + + L+ + + S + PG G+ N+ + Sbjct: 188 DITY----VLKPTFTKQQIANLD----------KQAKLSRAYDGTTYLPGIVGLNNIKAN 233 Query: 335 CYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVP 394 Y N+V+Q L ++P + +++ E ++N P V + G + Sbjct: 234 DYANAVLQALSNVPPLRNYFLE--EDNYKNIKRPPGDIMFLLVQRFGELM---------- 281 Query: 395 ESGDGERVPEQKEVQDGIAPR-MFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRS 453 ++ + + ++P M +A++ F +Q D +F +N + Sbjct: 282 -----RKLWNPRNFKAHVSPHEMLQAVVLCSKKTFQITKQGDGVDFLSWFLNALHSALGG 336 Query: 454 SENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL---EYEEKKR 510 + ++K K + T+ + + R+ + +LP P A KE+LL EY+E Sbjct: 337 T-----------KKKKKTIVTDVFQGSMRI-FTKKLPHPDLPAEEKEQLLHNDEYQETMV 384 Query: 511 QAEEEKMAL------------PELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVK 558 ++ + L +L+ QVP + L + + + + T K +K Sbjct: 385 ESTFMYLTLDLPTAPLYKDEKEQLIIPQVPLFNILAKFNGITEKE--YKT---YKENFLK 439 Query: 559 TTRFASFPDYLVIQIKKFT 577 + P YL+ IK+FT Sbjct: 440 RFQLTKLPPYLIFCIKRFT 458 >6H4H-A nrPDB Length = 560 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 23/27 (85%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQR 352 G++N+GN+C+ ++V+Q LF +P+F+R Sbjct: 15 VGLKNVGNTCWFSAVIQSLFQLPEFRR 41 >1OQY-A nrPDB Length = 368 Score = 39.7 bits (91), Expect = 0.006, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 28/39 (71%) Query: 725 EDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHI 763 E +T I+SMG+ R++ + ALRA+ N+ RAV+++ + I Sbjct: 169 ETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGI 207 >6HEH-A nrPDB Length = 382 Score = 39.7 bits (91), Expect = 0.006, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 23/27 (85%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQR 352 G++N+GN+C+ ++V+Q LF +P+F+R Sbjct: 15 VGLKNVGNTCWFSAVIQSLFQLPEFRR 41 >1VJV-A nrPDB Length = 415 Score = 38.9 bits (89), Expect = 0.010, Method: Compositional matrix adjust. Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 39/135 (28%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLL 385 G +N+GN+CYLN+ +Q L+ + D + ++ +P+Q S G Sbjct: 25 VGFKNMGNTCYLNATLQALYRVNDLRDMILN----------YNPSQGVSNS------GAQ 68 Query: 386 SGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL--------IGKGHPEFSTN------ 431 E K + V E K + + + FK++ + K +P+F+ Sbjct: 69 DEEIHKQI--------VIEMKRCFENLQNKSFKSVLPVVLLNTLRKCYPQFAERDSQGGF 120 Query: 432 -RQQDAQEFFLHLIN 445 +QQDA+E F L + Sbjct: 121 YKQQDAEELFTQLFH 135 Score = 38.1 bits (87), Expect = 0.018, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIK---KEGRWVIYNDQKVCASEK 842 Y L I+H G ++ GHY I+ E +W +ND KV EK Sbjct: 346 YNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEK 390 >5MPC-8 nrPDB Length = 499 Score = 38.9 bits (89), Expect = 0.010, Method: Compositional matrix adjust. Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 39/135 (28%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLL 385 G +N+GN+CYLN+ +Q L+ + D + ++ +P+Q S G Sbjct: 109 VGFKNMGNTCYLNATLQALYRVNDLRDMILN----------YNPSQGVSNS------GAQ 152 Query: 386 SGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL--------IGKGHPEFSTN------ 431 E K + V E K + + + FK++ + K +P+F+ Sbjct: 153 DEEIHKQI--------VIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGF 204 Query: 432 -RQQDAQEFFLHLIN 445 +QQDA+E F L + Sbjct: 205 YKQQDAEELFTQLFH 219 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIK---KEGRWVIYNDQKVCASEK 842 Y L I+H G ++ GHY I+ E +W +ND KV EK Sbjct: 430 YNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEK 474 >5WCH-A nrPDB Length = 421 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 13/25 (52%), Positives = 20/25 (80%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIP 348 G+ G++N G +CY+NSV+Q L+ IP Sbjct: 6 GFVGLKNAGATCYMNSVIQQLYMIP 30 >5TXK-A nrPDB Length = 372 Score = 37.4 bits (85), Expect = 0.027, Method: Compositional matrix adjust. Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 30/125 (24%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 G G+ NLGN+ Y+NS++Q LF DF R V +L + + +Q T++ L G Sbjct: 17 GKIGLINLGNTSYVNSILQALFMASDF-RHCVLRLTE-------NNSQPLMTKLQWL-FG 67 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 L E+S+ + I+P F L P FS QQD E+ +L Sbjct: 68 FL--EHSQ-----------------RPAISPENF--LSASWTPWFSPGTQQDCSEYLKYL 106 Query: 444 INMVE 448 ++ + Sbjct: 107 LDRLH 111 >5O71-A nrPDB Length = 716 Score = 37.0 bits (84), Expect = 0.037, Method: Compositional matrix adjust. Identities = 11/27 (40%), Positives = 23/27 (85%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQR 352 G++N+GN+C+ ++V+Q LF++ +F+R Sbjct: 171 VGLKNVGNTCWFSAVIQSLFNLLEFRR 197 Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 3/42 (7%) Query: 801 YQLFAFISHMGTSTMCGHYVCHI--KKEGRWVIYNDQKVCAS 840 Y+L A + H G + GHY +I +E RW+ YND V S Sbjct: 593 YRLHAVLVHEGQAN-AGHYWAYIFDHRESRWMKYNDIAVTKS 633 >6H4J-A nrPDB Length = 552 Score = 37.0 bits (84), Expect = 0.039, Method: Compositional matrix adjust. Identities = 11/27 (40%), Positives = 23/27 (85%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQR 352 G++N+GN+C+ ++V+Q LF++ +F+R Sbjct: 15 VGLKNVGNTCWFSAVIQSLFNLLEFRR 41 Score = 33.9 bits (76), Expect = 0.35, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 3/42 (7%) Query: 801 YQLFAFISHMGTSTMCGHYVCHI--KKEGRWVIYNDQKVCAS 840 Y+L A + H G + GHY +I +E RW+ YND V S Sbjct: 437 YRLHAVLVHEGQAN-AGHYWAYIFDHRESRWMKYNDIAVTKS 477 >5G0F-A nrPDB Length = 110 Score = 37.0 bits (84), Expect = 0.041, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 6/82 (7%) Query: 199 CSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADV 258 C +C W+ L +LCGR N H V H +E+G+P+ + ++ Sbjct: 28 CEECGGEAENWICLFCYKVLCGRYV------NQHMVTHGQESGHPVVLSFADLSVWCYAC 81 Query: 259 YSYDEDDMVLDPSLAEHLSHFG 280 SY + ++ + A HL FG Sbjct: 82 ESYVHNKVLHEAKNAAHLVKFG 103 >2F1Z-A nrPDB Length = 522 Score = 36.6 bits (83), Expect = 0.043, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 8/55 (14%) Query: 314 GVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTD 368 GV GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 164 GVAWDSKKHTGYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE 210 >5JTV-A nrPDB Length = 594 Score = 36.6 bits (83), Expect = 0.045, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 8/45 (17%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTD 368 GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 21 GYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE 57 >5JTJ-A nrPDB Length = 387 Score = 36.6 bits (83), Expect = 0.054, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 8/45 (17%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTD 368 GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 21 GYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE 57 >5J7T-A nrPDB Length = 671 Score = 36.6 bits (83), Expect = 0.054, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 8/45 (17%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTD 368 GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 2 GYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE 38 >3C5K-A nrPDB Length = 109 Score = 35.4 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 6/85 (7%) Query: 199 CSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADV 258 C C + W+ L+ + CGR Y +G H ++H+ +G+PL + ++ Sbjct: 27 CGDCGTIQENWVCLSCYQVYCGR-YING-----HMLQHHGNSGHPLVLSYIDLSAWCYYC 80 Query: 259 YSYDEDDMVLDPSLAEHLSHFGIDM 283 +Y +LD H + FG DM Sbjct: 81 QAYVHHQALLDVKNIAHQNKFGEDM 105 >5GVI-A nrPDB Length = 444 Score = 34.7 bits (78), Expect = 0.19, Method: Compositional matrix adjust. Identities = 36/123 (29%), Positives = 58/123 (47%), Gaps = 18/123 (14%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ NLGN+ ++NS++Q L + P F R D QN+ + TQ+++ LL Sbjct: 8 GLLNLGNTAFMNSLLQGLAACPSFIRWLEDFTS---QNSADRERTERETQLSRSLMQLLK 64 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL-IGKGHPEFSTNRQQDAQEFFLHLIN 445 S VP + +V D A + +AL + + H S+ +QDA E F L + Sbjct: 65 ALSS----------HVPGEDDVLD--AGGLLEALRLYRWH--ISSFEEQDAHELFHVLTS 110 Query: 446 MVE 448 +E Sbjct: 111 SLE 113 >5OHK-A nrPDB Length = 336 Score = 34.3 bits (77), Expect = 0.26, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 20/26 (76%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQR 352 G+ NLGN+C++NS++Q L + P F R Sbjct: 8 GLVNLGNTCFMNSLLQGLSACPAFIR 33 >5OHN-A nrPDB Length = 370 Score = 33.9 bits (76), Expect = 0.27, Method: Compositional matrix adjust. Identities = 13/26 (50%), Positives = 20/26 (76%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQR 352 G+ NLGN+C++NS++Q L + P F R Sbjct: 8 GLVNLGNTCFMNSLLQGLSACPAFIR 33 >6HOZ-A nrPDB Length = 350 Score = 30.8 bits (68), Expect = 2.5, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 333 NSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYS-- 390 ++ +V+Q L + PDF VD ++ + +PT+ + V ++ LLS +YS Sbjct: 58 DTAMTRAVIQSLIAKPDFDE--VDMAKRFAEEYKKEPTRGYGAGVVQVFKKLLSPKYSDV 115 Query: 391 -KPVPESGDGE 400 +P E DG+ Sbjct: 116 FQPAREQFDGK 126 >5EZ1-A nrPDB Length = 277 Score = 30.0 bits (66), Expect = 5.1, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 464 LVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPE 521 L+++ I+ E T+++D + M+A + K+ L+E+ KK+ E +K+ +PE Sbjct: 51 LIDQAIRTALVENEAKTEKLDSTPEFKAMMEA-VKKQALVEFWAKKQAEEVKKVQIPE 107 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3IHP-A nrPDB 1458 0.0 2G45-A nrPDB 283 2e-76 6CPM-C nrPDB 275 6e-74 4FIP-A nrPDB 275 6e-74 2GFO-A nrPDB 268 6e-72 2Y6E-A nrPDB 255 5e-68 5L8W-A nrPDB 253 3e-67 5K1A-A nrPDB 250 3e-66 2L80-A nrPDB 245 5e-65 5L8H-A nrPDB 235 8e-62 5GJQ-x nrPDB 207 2e-53 2AYN-A nrPDB 206 3e-53 6DGF-A nrPDB 198 1e-50 3MTN-A nrPDB 168 1e-41 4AE4-A nrPDB 87 4e-17 1WGN-A nrPDB 74 2e-13 Sequences not found previously or not previously below threshold: 5OHN-A nrPDB 102 5e-22 5TXK-A nrPDB 102 6e-22 5GVI-A nrPDB 102 8e-22 5WCH-A nrPDB 99 8e-21 5OHK-A nrPDB 96 7e-20 5CHV-A nrPDB 87 3e-17 5MPC-8 nrPDB 82 8e-16 1VJV-A nrPDB 82 1e-15 3JCR-V nrPDB 80 4e-15 6H4H-A nrPDB 74 2e-13 5JTV-A nrPDB 72 7e-13 5JTJ-A nrPDB 72 8e-13 2F1Z-A nrPDB 72 9e-13 5J7T-A nrPDB 72 1e-12 5O71-A nrPDB 71 2e-12 6H4J-A nrPDB 70 4e-12 6HEH-A nrPDB 64 3e-10 3C5K-A nrPDB 41 0.002 5G0F-A nrPDB 37 0.029 4I6Z-A nrPDB 33 0.72 3G25-A nrPDB 32 0.85 1DBH-A nrPDB 32 1.1 1XDV-A nrPDB 32 1.4 6QPR-A nrPDB 32 1.4 4YIR-X nrPDB 31 1.9 5IEF-A nrPDB 30 4.4 2OLM-A nrPDB 29 7.9 >3IHP-A nrPDB Length = 854 Score = 1458 bits (3774), Expect = 0.0, Method: Composition-based stats. Identities = 834/858 (97%), Positives = 835/858 (97%), Gaps = 23/858 (2%) Query: 1 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 60 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER Sbjct: 20 MAELSEEALLSVLPTIRVPKAGDRVHKDECAFSFDTPESEGGLYICMNTFLGFGKQYVER 79 Query: 61 HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 120 HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV Sbjct: 80 HFNKTGQRVYLHLRRTRRPKEEDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDEDV 139 Query: 121 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 180 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA Sbjct: 140 KIVILPDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQVSKHA 199 Query: 181 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 240 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET Sbjct: 200 FSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRET 259 Query: 241 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 300 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM Sbjct: 260 GYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKTDKTMTELEIDM 319 Query: 301 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 360 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK Sbjct: 320 NQRIGEWELIQESGVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEK 379 Query: 361 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 420 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL Sbjct: 380 IFQNAPTDPTQDFSTQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKAL 439 Query: 421 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 480 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT Sbjct: 440 IGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYT 499 Query: 481 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 540 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE Sbjct: 500 QRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPE 559 Query: 541 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS Sbjct: 560 QVDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 619 Query: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVI 660 QLRGTGLQPGEEELPDIAPPLVTPDEPK +PMLDESVI Sbjct: 620 QLRGTGLQPGEEELPDIAPPLVTPDEPK-----------------------APMLDESVI 656 Query: 661 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 720 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA Sbjct: 657 IQLVEMGFPMDACRKAVYYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAA 716 Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 780 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA Sbjct: 717 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSA 776 Query: 781 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 840 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS Sbjct: 777 ADSISESVPVGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKVCAS 836 Query: 841 EKPPKDLGYIYFYQRVAS 858 EKPPKDLGYIYFYQRVAS Sbjct: 837 EKPPKDLGYIYFYQRVAS 854 >2G45-A nrPDB Length = 129 Score = 283 bits (723), Expect = 2e-76, Method: Composition-based stats. Identities = 129/129 (100%), Positives = 129/129 (100%) Query: 163 KQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR 222 KQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR Sbjct: 1 KQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRR 60 Query: 223 YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGID 282 YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGID Sbjct: 61 YFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGID 120 Query: 283 MLKMQKTDK 291 MLKMQKTDK Sbjct: 121 MLKMQKTDK 129 >6CPM-C nrPDB Length = 349 Score = 275 bits (703), Expect = 6e-74, Method: Composition-based stats. Identities = 71/294 (24%), Positives = 128/294 (43%), Gaps = 37/294 (12%) Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDK--LEKIFQNAPTDPTQDFSTQVAKL 380 PG G+ NLGN+C++NS +Q L + P +++ E++ + P + + A+L Sbjct: 17 PGLCGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAEL 76 Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440 + SG++S + PR FK +G+ P+FS +QQD QE Sbjct: 77 IKQMWSGKFS--------------------YVTPRAFKTQVGRFAPQFSGYQQQDCQELL 116 Query: 441 LHLINMVERNC-RSSENPNEVFRFLVEEKIKCLATEKVK-YTQRVDYIMQLPVPMDAALN 498 L++ + + R + P + K +A E + + +R D I+ V + L Sbjct: 117 AFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSII---VDIFHGLF 173 Query: 499 KEELLEYEEKKRQAEEEK-----MALPELVRAQVPFSSCLEAYGAPEQV---DDFWSTAL 550 K L+ E K + + LP + V C+E + E++ D ++ Sbjct: 174 KSTLVCPECAKISVTFDPFCYLTLPLPMPKKPFVKLKDCIELFTTKEKLGAEDPWYCPNC 233 Query: 551 QAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQLR 603 + A K S P LV+ +K+F++ ++ KLD ++ P +LD+S R Sbjct: 234 KEHQQATKKLDLWSLPPVLVVHLKRFSYS-RYMRDKLDTLVDFPINDLDMSGCR 286 Score = 49.0 bits (115), Expect = 9e-06, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 42/121 (34%), Gaps = 15/121 (12%) Query: 741 ALKALRATNN-SLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPG 799 + +AT L + H+ M + + D + D G Sbjct: 233 CKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMR-DKLDTLVDFPINDL-------DMSG 284 Query: 800 -KYQLFAFISHMGTSTMCGHYVCHIKKE--GRWVIYNDQKV--CASEKPPKDLGYIYFYQ 854 +Y L A +H G HY K + G+W ++D V + ++ Y+ FYQ Sbjct: 285 CRYNLIAVSNHYGGMGGG-HYTAFAKNKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQ 343 Query: 855 R 855 R Sbjct: 344 R 344 >4FIP-A nrPDB Length = 476 Score = 275 bits (703), Expect = 6e-74, Method: Composition-based stats. Identities = 76/330 (23%), Positives = 126/330 (38%), Gaps = 61/330 (18%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 G +G+ N+GN+C+++S++Q L P F R + ++ P + FS + K+ H Sbjct: 140 GLSGLINMGNTCFMSSILQCLIHNPYFIRHSMSQIHS-NNCKVRSPDKCFSCALDKIVHE 198 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 L +K S Q G + A K + + QQDA EF+ + Sbjct: 199 LYGALNTKQASSSSTSTN------RQTGFIYLLTCAW--KINQNLAGYSQQDAHEFWQFI 250 Query: 444 INMVER-------NCRSSENPNE---------VFRFLVEEKIKCLATEKVKYTQRVDYIM 487 IN + + N + N VF +E I C + T +D + Sbjct: 251 INQIHQSYVLDLPNAKEVSRANNKQCECIVHTVFEGSLESSIVCPGCQNNSKT-TIDPFL 309 Query: 488 QLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWS 547 L L+ ++KK+ E CL+++ EQ+ DF Sbjct: 310 DLS------------LDIKDKKKLYE------------------CLDSFHKKEQLKDFNY 339 Query: 548 TALQAK--SVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGT 605 + A+K P LV+Q+K+F L+ +KLD IE P L++ T Sbjct: 340 HCGECNSTQDAIKQLGIHKLPSVLVLQLKRFEHLLNGSNRKLDDFIEFPTYLNMKNYCST 399 Query: 606 GLQPGEEE---LPDIAPPLVTPDEPKGSLG 632 + E +PDI L+ KG++ Sbjct: 400 KEKDKHSENGKVPDIIYELIGIVSHKGTVN 429 Score = 47.8 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 4/56 (7%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIKKEGR-WVIYNDQKV--CASEKPPKDLGYIYFY 853 Y+L +SH GT GHY+ K G W +ND V + E+ K+ Y+ FY Sbjct: 416 YELIGIVSHKGT-VNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYLLFY 470 >2GFO-A nrPDB Length = 396 Score = 268 bits (685), Expect = 6e-72, Method: Composition-based stats. Identities = 74/297 (24%), Positives = 134/297 (45%), Gaps = 32/297 (10%) Query: 317 LKPLFG---PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDF 373 L P+FG P TG+RNLGN+CY+NS++Q L + P + + QD Sbjct: 51 LNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYF-----------NRNCYQDD 99 Query: 374 STQVAKLGH-GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNR 432 + LGH G ++ E+ + G+ I+P+ FK IGK + +F+ Sbjct: 100 INRSNLLGHKGEVAEEFGIIMKALWTGQ--------YRYISPKDFKITIGKINDQFAGYS 151 Query: 433 QQDAQEFFLHLINMVERNCRSSENPNEVFRFLVE--EKIKCLATEKVKYTQRVDYIMQLP 490 QQD+QE L L++ + + ++N + + K K+ Q + I+ + Sbjct: 152 QQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII-VA 210 Query: 491 VPMDAALNKEELLEYEEKKRQAE-EEKMALPELVRAQVPFSSCLEAYGAPEQVDD---FW 546 + + + L +K R E ++LP ++ CL + E++ D F+ Sbjct: 211 LFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFY 270 Query: 547 STALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEE-LDISQL 602 + +A+ ++K P L++ +K+F++ W +KL S++ P E LD+SQ Sbjct: 271 CSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQY 326 >2Y6E-A nrPDB Length = 367 Score = 255 bits (652), Expect = 5e-68, Method: Composition-based stats. Identities = 77/350 (22%), Positives = 133/350 (38%), Gaps = 82/350 (23%) Query: 323 PGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYV-DKLE-KIFQNAPTDPTQDFSTQVAKL 380 PG G+ NLGN+C++NS +Q L + ++ D+ E +I ++ P + + A+L Sbjct: 6 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 65 Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440 + SG + +APRMFK +G+ P+FS +QQD+QE Sbjct: 66 IKQMWSGRDAH--------------------VAPRMFKTQVGRFAPQFSGYQQQDSQELL 105 Query: 441 LHLINMVERNC-RSSENPN-------------------------------EVFRFLVEEK 468 L++ + + R + P + F L + Sbjct: 106 AFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKST 165 Query: 469 IKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVR-AQV 527 + C KV T + LP+P+ KK + E M P+ + V Sbjct: 166 LVCPECAKVSVTFDPFCYLTLPLPL--------------KKDRVMEGPMLQPQKKKKTTV 211 Query: 528 PFSSCLEAYGAPEQV---DDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVP 584 C+E + E + D ++ + A K S P LV+ +K+F++ W Sbjct: 212 ALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYW-R 270 Query: 585 KKLDVSIEMPEE-LDISQL-RGTGLQPGEEELPDIAPPLVTPDEPKGSLG 632 KLD +E P L++S+ +P L+ G++G Sbjct: 271 DKLDTVVEFPIRGLNMSEFVCNLSARP-------YVYDLIAVSNHYGAMG 313 Score = 61.7 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 45/146 (30%), Gaps = 17/146 (11%) Query: 725 EDCVTTIVSMG--------FSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISE 776 DC+ +M + + L + H+ Sbjct: 214 RDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKL 273 Query: 777 GRSAADSISESVPVGPKV---RDGPGKYQLFAFISHMGTSTMCGHYVCHIKKE--GRWVI 831 + + + V P Y L A +H G + GHY + K + G+W Sbjct: 274 DTV-VEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYG-AMGVGHYTAYAKNKLNGKWYY 331 Query: 832 YNDQKV--CASEKPPKDLGYIYFYQR 855 ++D V + ++ Y+ FYQR Sbjct: 332 FDDSNVSLASEDQIVTKAAYVLFYQR 357 >5L8W-A nrPDB Length = 376 Score = 253 bits (645), Expect = 3e-67, Method: Composition-based stats. Identities = 66/314 (21%), Positives = 108/314 (34%), Gaps = 48/314 (15%) Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384 Y G+ N GN+CY NSV+Q L+ F+ K + + + T +A L H Sbjct: 44 YFGLVNFGNTCYCNSVLQALYFCRPFREKV------LAYKSQPRKKESLLTCLADLFHS- 96 Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444 + QK+ I P+ F + K + F QQDA EF +L+ Sbjct: 97 -----------------IATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLL 139 Query: 445 NMVE---RNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 N + + R E N + +T + + L E Sbjct: 140 NTIADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEI---------FQGTLTNET 190 Query: 502 LLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVD---DFWSTALQAKSVAVK 558 E +E+ + L V + CL + E + ++ ++K A K Sbjct: 191 RCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHK 250 Query: 559 TTRFASFPDYLVIQIKKFTFGLDWVPK--KLDVSIEMPEELDISQLRGTGLQPGEEELPD 616 + P L + +K+F + +D + + KL + P EL + G PD Sbjct: 251 RMKVKKLPMILALHLKRFKY-MDQLHRYTKLSYRVVFPLELRLFNTSGDATN------PD 303 Query: 617 IAPPLVTPDEPKGS 630 LV GS Sbjct: 304 RMYDLVAVVVHCGS 317 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 22/137 (16%), Positives = 44/137 (32%), Gaps = 19/137 (13%) Query: 736 FSRDQALKALRATNNSLERAVDWIFSHIDDLD-AEAAMDISEGRSAADSISESVPVGPKV 794 + + K +++ + H+ + ++ E + + Sbjct: 238 YCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTS 296 Query: 795 RDGPGK---YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV-------------- 837 D Y L A + H G+ GHY+ +K W++++D V Sbjct: 297 GDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGL 356 Query: 838 CASEKPPKDLGYIYFYQ 854 + + GYI FYQ Sbjct: 357 TSDISKNSESGYILFYQ 373 >5K1A-A nrPDB Length = 331 Score = 250 bits (637), Expect = 3e-66, Method: Composition-based stats. Identities = 65/312 (20%), Positives = 107/312 (34%), Gaps = 48/312 (15%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ N GN+CY NSV+Q L+ F+ K + + + T +A L H Sbjct: 1 GLVNFGNTCYCNSVLQALYFCRPFREKV------LAYKSQPRKKESLLTCLADLFHS--- 51 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINM 446 + QK+ I P+ F + K + F QQDA EF +L+N Sbjct: 52 ---------------IATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNT 96 Query: 447 VE---RNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL 503 + + R E N + +T + + L E Sbjct: 97 IADILQEERKQEKQNGRLPNGNIDNENNNSTPDPTWVHEI---------FQGTLTNETRC 147 Query: 504 EYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVD---DFWSTALQAKSVAVKTT 560 E +E+ + L V + CL + E + ++ ++K A K Sbjct: 148 LTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRM 207 Query: 561 RFASFPDYLVIQIKKFTFGLDWVPK--KLDVSIEMPEELDISQLRGTGLQPGEEELPDIA 618 + P L + +K+F + +D + + KL + P EL + G PD Sbjct: 208 KVKKLPMILALHLKRFKY-MDQLHRYTKLSYRVVFPLELRLFNTSGDATN------PDRM 260 Query: 619 PPLVTPDEPKGS 630 LV GS Sbjct: 261 YDLVAVVVHCGS 272 Score = 42.8 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 22/137 (16%), Positives = 44/137 (32%), Gaps = 19/137 (13%) Query: 736 FSRDQALKALRATNNSLERAVDWIFSHIDDLD-AEAAMDISEGRSAADSISESVPVGPKV 794 + + K +++ + H+ + ++ E + + Sbjct: 193 YCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTS 251 Query: 795 RDGPGK---YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV-------------- 837 D Y L A + H G+ GHY+ +K W++++D V Sbjct: 252 GDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGL 311 Query: 838 CASEKPPKDLGYIYFYQ 854 + + GYI FYQ Sbjct: 312 TSDISKNSESGYILFYQ 328 >2L80-A nrPDB Length = 116 Score = 245 bits (626), Expect = 5e-65, Method: Composition-based stats. Identities = 84/115 (73%), Positives = 99/115 (86%) Query: 175 QVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAV 234 VSK+A +L QLDN RIPP GWKC++CD+RENLWLNLTDGS+LCG+ +FD SGGN HA+ Sbjct: 2 SVSKYANNLTQLDNGVRIPPSGWKCARCDLRENLWLNLTDGSVLCGKWFFDSSGGNGHAL 61 Query: 235 EHYRETGYPLAVKLGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQKT 289 EHYR+ GYPLAVKLGTITPDGADVYS+ E++ VLDP LA+HL+HFGIDML M T Sbjct: 62 EHYRDMGYPLAVKLGTITPDGADVYSFQEEEPVLDPHLAKHLAHFGIDMLHMHGT 116 >5L8H-A nrPDB Length = 359 Score = 235 bits (598), Expect = 8e-62, Method: Composition-based stats. Identities = 62/314 (19%), Positives = 109/314 (34%), Gaps = 48/314 (15%) Query: 325 YTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGL 384 Y G+ N GN+CY+NSV+Q L+ F+ + A ++ T +A L H Sbjct: 27 YFGLVNFGNTCYVNSVLQALYFCRPFRENV------LAYKAQQKKKENLLTCLADLFHS- 79 Query: 385 LSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLI 444 + QK+ I P+ F + + K + F QQDA EF +L+ Sbjct: 80 -----------------IATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLL 122 Query: 445 NMVE---RNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 N + + + E N + + ++ + + L E Sbjct: 123 NTIADILQEEKKQEKQNGKLKNGNMNEPAENNKPELTWVHEI---------FQGTLTNET 173 Query: 502 LLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVD---DFWSTALQAKSVAVK 558 E +E+ + L V + CL + E + ++ +K A K Sbjct: 174 RCLNCETVSSKDEDFLDLSVDVEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 233 Query: 559 TTRFASFPDYLVIQIKKFTFGLDWVPK--KLDVSIEMPEELDISQLRGTGLQPGEEELPD 616 R P L + +K+F + ++ + + KL + P EL + + D Sbjct: 234 RMRVKKLPMILALHLKRFKY-MEQLRRYTKLSYRVVFPLELRLFNTSSDAVN------LD 286 Query: 617 IAPPLVTPDEPKGS 630 LV GS Sbjct: 287 RMYDLVAVVVHCGS 300 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 44/137 (32%), Gaps = 19/137 (13%) Query: 736 FSRDQALKALRATNNSLERAVDWIFSHIDDLD-AEAAMDISEGRSAADSISESVPVGPKV 794 + K +++ + H+ E ++ E + + Sbjct: 221 YCETCCSKQEAQKRMRVKKLPMILALHLKRFKYMEQLRRYTKLSYRVVFPLE-LRLFNTS 279 Query: 795 RDGPG---KYQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV-------------- 837 D Y L A + H G+ GHY+ +K G W++++D V Sbjct: 280 SDAVNLDRMYDLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGL 339 Query: 838 CASEKPPKDLGYIYFYQ 854 + + GYI FYQ Sbjct: 340 TSDISKNSESGYILFYQ 356 >5GJQ-x nrPDB Length = 494 Score = 207 bits (527), Expect = 2e-53, Method: Composition-based stats. Identities = 55/302 (18%), Positives = 120/302 (39%), Gaps = 57/302 (18%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLL 385 G+ NLGN+CY+N+ VQ + S+P+ + D + ++ + G + Sbjct: 105 CGLTNLGNTCYMNATVQCIRSVPELK----------------DALKRYAGALRASGE-MA 147 Query: 386 SGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFST------NRQQDAQEF 439 S +Y + + + I P + + P+F+ QQDA E Sbjct: 148 SAQYIT----AALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANEC 203 Query: 440 FLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNK 499 ++ ++ ++++K++ + + VK T P + +++ Sbjct: 204 WIQMMR------------------VLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQ 245 Query: 500 EELLEY----------EEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTA 549 +E+ EE+ + +E ++ L + +V + E++ S Sbjct: 246 FFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK-QSPT 304 Query: 550 LQAKSVAVKTTRFASFPDYLVIQIKKFTFG-LDWVPKKLDVSIEMPEELDISQLRGTGLQ 608 LQ ++ +K+++ + P YL IQ+ +F + + V K+ ++ P LD+ +L LQ Sbjct: 305 LQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQ 364 Query: 609 PG 610 Sbjct: 365 EK 366 Score = 39.7 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 7/84 (8%) Query: 761 SHIDDLDAEAAMDISEGRSAADSISESVPVGPKV------RDGPGKYQLFAFISHMGTST 814 S DL+ + S + V P + G Y L A ++H G S+ Sbjct: 372 SKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSS 431 Query: 815 MCGHYVCHI-KKEGRWVIYNDQKV 837 GHYV + +K+ W+ ++D KV Sbjct: 432 SSGHYVSWVKRKQDEWIKFDDDKV 455 >2AYN-A nrPDB Length = 404 Score = 206 bits (525), Expect = 3e-53, Method: Composition-based stats. Identities = 55/302 (18%), Positives = 120/302 (39%), Gaps = 57/302 (18%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLL 385 G+ NLGN+CY+N+ VQ + S+P+ + D + ++ + G + Sbjct: 15 CGLTNLGNTCYMNATVQCIRSVPELK----------------DALKRYAGALRASGE-MA 57 Query: 386 SGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFST------NRQQDAQEF 439 S +Y + + + I P + + P+F+ QQDA E Sbjct: 58 SAQYIT----AALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANEC 113 Query: 440 FLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNK 499 ++ ++ ++++K++ + + VK T P + +++ Sbjct: 114 WIQMMR------------------VLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQ 155 Query: 500 EELLEY----------EEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTA 549 +E+ EE+ + +E ++ L + +V + E++ S Sbjct: 156 FFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITK-QSPT 214 Query: 550 LQAKSVAVKTTRFASFPDYLVIQIKKFTFG-LDWVPKKLDVSIEMPEELDISQLRGTGLQ 608 LQ ++ +K+++ + P YL IQ+ +F + + V K+ ++ P LD+ +L LQ Sbjct: 215 LQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQ 274 Query: 609 PG 610 Sbjct: 275 EK 276 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 7/84 (8%) Query: 761 SHIDDLDAEAAMDISEGRSAADSISESVPVGPKV------RDGPGKYQLFAFISHMGTST 814 S DL+ + S + V P + G Y L A ++H G S+ Sbjct: 282 SKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSS 341 Query: 815 MCGHYVCHI-KKEGRWVIYNDQKV 837 GHYV + +K+ W+ ++D KV Sbjct: 342 SSGHYVSWVKRKQDEWIKFDDDKV 365 >6DGF-A nrPDB Length = 370 Score = 198 bits (502), Expect = 1e-50, Method: Composition-based stats. Identities = 63/326 (19%), Positives = 115/326 (35%), Gaps = 43/326 (13%) Query: 317 LKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQ 376 + G G+RNLGN+C++NS++Q L + + + + +L Sbjct: 23 MNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLY----------------- 65 Query: 377 VAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDA 436 + L HG S ++ V E + D ++P FK I + P F QQDA Sbjct: 66 MRDLHHG--SNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDA 123 Query: 437 QEFFLHLINMVERN-----CRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPV 491 QEF L++ + R NP + +EK + + KY +R D + + Sbjct: 124 QEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWR---KYLEREDSRIG-DL 179 Query: 492 PMDAALNKEELLEYEEKKRQAE-EEKMALPELVR--AQVPFSSCLEAYGAPEQVDDFWST 548 + + + + ++LP R +V C+ + + +D Sbjct: 180 FVGQLKSSLTCTDCGYCSTVFDPFWDLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKP 239 Query: 549 A---LQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPE-ELDISQLRG 604 + + +K FP LV+ +K+F+ KL + P +LD+ + Sbjct: 240 TCCRCRGRKRCIKKFSIQRFPKILVLHLKRFS-ESRIRTSKLTTFVNFPLRDLDLREFAS 298 Query: 605 TGLQPGEEELPDIAPPLVTPDEPKGS 630 L G+ Sbjct: 299 ENTNHA-------VYNLYAVSNHSGT 317 Score = 79.0 bits (193), Expect = 8e-15, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 44/113 (38%), Gaps = 8/113 (7%) Query: 748 TNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDGPGK--YQLFA 805 S++R + H+ + S+ + + + + + Y L+A Sbjct: 252 KKFSIQRFPKILVLHLKRFSESR-IRTSKLTTFVNFPLRDLDLREFASENTNHAVYNLYA 310 Query: 806 FISHMGTSTMCGHYVCHIKK--EGRWVIYNDQKV--CASEKPPKDLGYIYFYQ 854 +H GT TM GHY + + G W +ND V +S + Y+ FY+ Sbjct: 311 VSNHSGT-TMGGHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYE 362 >3MTN-A nrPDB Length = 373 Score = 168 bits (425), Expect = 1e-41, Method: Composition-based stats. Identities = 61/343 (17%), Positives = 112/343 (32%), Gaps = 55/343 (16%) Query: 317 LKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQ 376 L P G+ G+RNLGN+C+LN+V+Q L S R + + + + Q+ + Sbjct: 14 LVPRGSSGHVGLRNLGNTCFLNAVLQCLSSTRPL-RDFCLRRDFRQEVPGGGRAQELTEA 72 Query: 377 VAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDA 436 A + L + + + P F+A+ K P FS QQDA Sbjct: 73 FADVIGALW-------------------HPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDA 113 Query: 437 QEFFLHLINMVERNCRSSENP------NEVFRFLVEEKIKCLATE-----------KVKY 479 QEF L+ + N L +Y Sbjct: 114 QEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRY 173 Query: 480 TQRVDYIMQLPVPMDAALNKEELLEYEEKKRQAE-EEKMALPELVR----AQVPFSSCLE 534 +R D + + + + + + + E ++LP + +V C Sbjct: 174 LEREDSKI-VDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFN 232 Query: 535 AYGAPEQVDDFW---STALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSI 591 + E+++ + K+ + K FP LV+ + +F+ + KK V + Sbjct: 233 LFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSI-KKSSVGV 291 Query: 592 EMPEE-LDISQLRGTGLQPGEEELPDIAPPLVTPDEPKGSLGF 633 + P + L + L GS+ + Sbjct: 292 DFPLQRLSLGDFASDKAGSP-------VYQLYALCNHSGSVHY 327 Score = 164 bits (415), Expect = 2e-40, Method: Composition-based stats. Identities = 31/121 (25%), Positives = 53/121 (43%), Gaps = 7/121 (5%) Query: 739 DQALKALRATNN-SLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVGPKVRDG 797 D+ + R+T +++R + H++ A I + D + + +G D Sbjct: 249 DRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRG-SIKKSSVGVDFPLQRLSLGDFASDK 307 Query: 798 PGK--YQLFAFISHMGTSTMCGHYVCHIKKEGRWVIYNDQKV--CASEKPPKDLGYIYFY 853 G YQL+A +H G S GHY + + W +YND +V + + GY+ FY Sbjct: 308 AGSPVYQLYALCNHSG-SVHYGHYTALCRCQTGWHVYNDSRVSPVSENQVASSEGYVLFY 366 Query: 854 Q 854 Q Sbjct: 367 Q 367 >5OHN-A nrPDB Length = 370 Score = 102 bits (255), Expect = 5e-22, Method: Composition-based stats. Identities = 48/331 (14%), Positives = 105/331 (31%), Gaps = 48/331 (14%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ NLGN+C++NS++Q L + P F R ++F++Q ++ S Sbjct: 8 GLVNLGNTCFMNSLLQGLSACPAFIRW----------------LEEFTSQYSRDQKEPPS 51 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINM 446 +Y ++ + + ++ + S+ +QDA E F + + Sbjct: 52 HQYLSLTLLHLLKALSCQEVTDDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSS 111 Query: 447 VERNCRSSENPNEVF--RFLVEEKI---KCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 +E +F L ++ K + + P L Sbjct: 112 LEDERDRQPRVTHLFDVHSLEQQSEITPKQITCRTRGSPHPTSNHWKSQHPFHGRLTSNM 171 Query: 502 LLEYEEKKRQAEEEK---MALPELVRA---QVPFSSCLEAYGAPEQVDDFWSTALQA--- 552 + ++ E + + ++L + CL + + E V D Sbjct: 172 VCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEA 231 Query: 553 ------------KSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600 ++ VK + P L I +++ ++ P K ++ E+LD+ Sbjct: 232 KGTLNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEDLDMD 291 Query: 601 QLRGTGLQPGEEELPDIAPPLVTPDEPKGSL 631 + + L+ G + Sbjct: 292 EYKY------HSNASTYLFRLMAVVVHHGDM 316 >5TXK-A nrPDB Length = 372 Score = 102 bits (255), Expect = 6e-22, Method: Composition-based stats. Identities = 47/285 (16%), Positives = 94/285 (32%), Gaps = 47/285 (16%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 G G+ NLGN+ Y+NS++Q LF DF R V +L + Q + Sbjct: 17 GKIGLINLGNTSYVNSILQALFMASDF-RHCVLRLTENNSQPLMTKLQWLFGFL------ 69 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 + + I+P F + P FS QQD E+ +L Sbjct: 70 ---------------------EHSQRPAISPENFLS--ASWTPWFSPGTQQDCSEYLKYL 106 Query: 444 INMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL 503 ++ + ++ + +K+K ++ + + Sbjct: 107 LDRLHEEEKTGTR--------ICQKLKQSSSPSPPEEPPAPSSTSVEKMFGGKIVTRICC 158 Query: 504 EYEEKKRQAEEEKMALPEL-----VRAQVPFSSCLEAYGAPEQVD---DFWSTALQAKSV 555 EE L + + +PE++ ++ + + Sbjct: 159 LCCLNVSSREEAFTDLSLAFPPPGSEGSRSVLDLVNYFLSPEKLTAENRYYCESCASLQD 218 Query: 556 AVKTTRFASFPDYLVIQIKKFTFGLDWV-PKKLDVSIEMPEELDI 599 A K + P YL++ + +F+F L + +K+ + +P L + Sbjct: 219 AEKVVELSQGPCYLILTLLRFSFDLRTMRRRKILDDVSIPLLLRL 263 Score = 29.3 bits (64), Expect = 7.6, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 61/179 (34%), Gaps = 37/179 (20%) Query: 708 PGSSGPGSTSAAAD--PPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDD 765 PGS G S + PE T + + A L + ++ + Sbjct: 181 PGSEGSRSVLDLVNYFLSPEKL--TAENRYYCESCASLQDAEKVVELSQGPCYLILTLLR 238 Query: 766 LDAEAAMDISEGRSAADSISESVPVGPKVRDGPGKYQLFAFISHMGTST---MCGHYVCH 822 + + R D + S+P+ ++ G+ Q + S + S GHY C+ Sbjct: 239 FSFD--LRTMRRRKILDDV--SIPLLLRLPLAGGRGQAYDLCSVVVHSGVSSESGHYYCY 294 Query: 823 IKK-----------------EGRWVIYNDQKVCASEKP---------PKDLGYIYFYQR 855 ++ E +W ++ND +V S PKD Y+ FY++ Sbjct: 295 AREGAARPAASLGTADRPEPENQWYLFNDTRVSFSSFESVSNVTSFFPKDTAYVLFYRQ 353 >5GVI-A nrPDB Length = 444 Score = 102 bits (253), Expect = 8e-22, Method: Composition-based stats. Identities = 52/303 (17%), Positives = 99/303 (32%), Gaps = 42/303 (13%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ NLGN+ ++NS++Q L + P F R D QN+ + TQ+++ LL Sbjct: 8 GLLNLGNTAFMNSLLQGLAACPSFIRWLED---FTSQNSADRERTERETQLSRSLMQLLK 64 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINM 446 S D + + S+ +QDA E F L + Sbjct: 65 ALSSHV-------------PGEDDVLDAGGLLEALRLYRWHISSFEEQDAHELFHVLTSS 111 Query: 447 VERNCRSSENPNEVF-----RFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 +E +F VE K K ++ + + + P L Sbjct: 112 LEEEQERQPRVAHLFDMQTLEKSVESKEKNISCRSGGPLHPIPSLWRTRHPFHGRLTSYM 171 Query: 502 LLEYEEKKRQA---EEEKMALPELVRA---QVPFSSCLEAYGAPEQVDDFWSTALQAKS- 554 + E++ + ++L V CL+ + + E + + + Sbjct: 172 ACKRCEQQSPVHYDSFDSLSLSIPSIQWGRPVTLDQCLQHFISSETIKEVECENCTKQQA 231 Query: 555 --------------VAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDIS 600 VK + P L I +++ T+ + P K ++ E L + Sbjct: 232 GELVNGEVLESQRTTFVKQLKLGKLPQCLCIHLQRLTWSKEGSPIKRQEHVQFTEYLSLD 291 Query: 601 QLR 603 + + Sbjct: 292 RYK 294 Score = 30.5 bits (67), Expect = 3.4, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 28/68 (41%), Gaps = 13/68 (19%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIKK------------EGRWVIYNDQKVCASEKPPKDLG 848 ++L A + H G GH++ + + + WV + + + ++ Sbjct: 369 FRLTAVLVHHG-DMHSGHFITYRRCPAAPRGTSPFSSQWLWVSDDSVRKASLQEVLSSSA 427 Query: 849 YIYFYQRV 856 Y+ FY+R+ Sbjct: 428 YLLFYERM 435 >5WCH-A nrPDB Length = 421 Score = 99.1 bits (245), Expect = 8e-21, Method: Composition-based stats. Identities = 66/350 (18%), Positives = 102/350 (29%), Gaps = 75/350 (21%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQ-------------RKYVDKLEKIFQNAPTDPT 370 G+ G++N G +CY+NSV+Q L+ IP + + EK + DP Sbjct: 6 GFVGLKNAGATCYMNSVIQQLYMIPSIRNGILAIEGTGSDVDDDMSGDEKQDNESNVDPR 65 Query: 371 QDFSTQVA------KLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKG 424 D L Y+ V PR F Sbjct: 66 DDVFGYPQQFEDKPALSKTEDRAAYNIGVLRHLQVIFGHLAASRLQYYVPRGFWKQFRLW 125 Query: 425 HPEFSTNRQQDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVD 484 + Q DA EFF L++ ++ ++ +P Sbjct: 126 GEPVNLREQHDALEFFNSLVDSLDEALKALGHP--------------------------- 158 Query: 485 YIMQLPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGA---PEQ 541 L + + +++ + + + EE L +R LE Y E Sbjct: 159 --AMLSKVLGGSFADQKICQGCPHRYECEESFTTLNVDIRNHQNLLDSLEQYVKGDLLEG 216 Query: 542 VDDFWSTALQAKSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPK---KLDVSIEMPEELD 598 + + K VK P L IQ+K+F + DW + K + E P ELD Sbjct: 217 ANAYHCEKCNKKVDTVKRLLIKKLPPVLAIQLKRFDY--DWERECAIKFNDYFEFPRELD 274 Query: 599 I-------------------SQLRGTGLQPGEEELPDIAPPLVTPDEPKG 629 + SQL Q E LV G Sbjct: 275 MEPYTVAGVAKLEGDNVNPESQLIQQSEQSESETAGSTKYRLVGVLVHSG 324 >5OHK-A nrPDB Length = 336 Score = 95.6 bits (236), Expect = 7e-20, Method: Composition-based stats. Identities = 49/327 (14%), Positives = 98/327 (29%), Gaps = 74/327 (22%) Query: 327 GIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLS 386 G+ NLGN+C++NS++Q L + P F R ++F++Q ++ S Sbjct: 8 GLVNLGNTCFMNSLLQGLSACPAFIRW----------------LEEFTSQYSRDQKEPPS 51 Query: 387 GEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINM 446 +Y ++ + + ++ + S+ +QDA E F H+I Sbjct: 52 HQYLSLTLLHLLKALSCQEVTDDEVLDASCLLDVLRMYRWQISSFEEQDAHELF-HVITS 110 Query: 447 VERNCRSSE----NPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEEL 502 + R F + + C E PV D Sbjct: 111 SLEDERDGSGSHWKSQHPFHGRLTSNMVCKHCEHQS-----------PVRFD-------- 151 Query: 503 LEYEEKKRQAEEEKMALPELVRA---QVPFSSCLEAYGAPEQVDDFWSTALQA------- 552 + ++L + CL + + E V D Sbjct: 152 ----------TFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTL 201 Query: 553 --------KSVAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRG 604 ++ VK + P L I +++ ++ P K ++ E+L + + + Sbjct: 202 NGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEDLSMDEYKY 261 Query: 605 TGLQPGEEELPDIAPPLVTPDEPKGSL 631 L+ G + Sbjct: 262 ------HSNASTYLFRLMAVVVHHGDM 282 >5CHV-A nrPDB Length = 323 Score = 86.7 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 56/320 (17%), Positives = 106/320 (33%), Gaps = 67/320 (20%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 G G+ N+G +C LNS++QV DF + ++ Sbjct: 5 GLVGLHNIGQTCCLNSLLQVFM-----------------------MNMDFRMILKRITVP 41 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGH-PEFSTNRQQDAQEFFLH 442 + E + VP Q Q + P + K + P F Q DA + +L Sbjct: 42 RSAEERKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFV---QHDAAQLYLT 98 Query: 443 LINMVER---NCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNK 499 + N+ + + +E +F +E + C+ Sbjct: 99 IWNLTKDQITDTDLTERLQGLFTIWTQESLICVGC------------------------- 133 Query: 500 EELLEYEEKKRQAEEEKMALPEL---VRAQVPFSSCLEAYGAPEQV--DDFWSTALQAKS 554 E R+++ ++LP + L + P+++ D + K+ Sbjct: 134 -----TAESSRRSKLLTLSLPLFDKDAKPLKTLEDALRCFVQPKELASSDMCCESCGEKT 188 Query: 555 VAVKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMPEELDISQLRGTGLQPGE-EE 613 + + P L I + +F+ + +K+ S+ P+ LD SQ+ T G+ +E Sbjct: 189 PWKQVLKLTHLPQTLTIHLMRFS-ARNSRTEKICHSVNFPQSLDFSQVLPTEEDLGDTKE 247 Query: 614 LPDIAPPLVTPDEPKGSLGF 633 +I L G F Sbjct: 248 QSEIHYELFAVIAHVGMADF 267 Score = 45.9 bits (107), Expect = 8e-05, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 13/98 (13%) Query: 752 LERAVDWIFSHIDDLDAEAAMDISEGRSAADSI-----SESVP----VGPKVRDGPGKYQ 802 L + H+ A + + + S+ +P +G Y+ Sbjct: 196 LTHLPQTLTIHLMRFSA-RNSRTEKICHSVNFPQSLDFSQVLPTEEDLGDTKEQSEIHYE 254 Query: 803 LFAFISHMGTSTMCGHYVCHIKK--EGRWVIYNDQKVC 838 LFA I+H+G + GHY +I+ +G+W +ND VC Sbjct: 255 LFAVIAHVGMAD-FGHYCAYIRNPVDGKWFCFNDSHVC 291 >4AE4-A nrPDB Length = 118 Score = 86.7 bits (213), Expect = 4e-17, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 37/65 (56%), Gaps = 7/65 (10%) Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSH-------IDDLDAEAAMD 773 P CV T+V+MG+S + L+A++A ++E+ +D++F+H D L E A++ Sbjct: 5 SPSERQCVETVVNMGYSYECVLRAMKAAGANIEQILDYLFAHGQLCEKGFDPLLVEEALE 64 Query: 774 ISEGR 778 + + Sbjct: 65 MHQCS 69 >5MPC-8 nrPDB Length = 499 Score = 82.5 bits (202), Expect = 8e-16, Method: Composition-based stats. Identities = 53/299 (17%), Positives = 103/299 (34%), Gaps = 57/299 (19%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLL 385 G +N+GN+CYLN+ +Q L+ + D + ++ +P+Q S G Sbjct: 109 VGFKNMGNTCYLNATLQALYRVNDLRDMILN----------YNPSQGVSNS------GAQ 152 Query: 386 SGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFST-------NRQQDAQE 438 E K + Q + + P + + K +P+F+ +QQDA+E Sbjct: 153 DEEIHKQIVIEMKRCFENLQNKSFKSVLPIVLLNTLRKCYPQFAERDSQGGFYKQQDAEE 212 Query: 439 FFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALN 498 F L + + + + +E FR + IK A + + Sbjct: 213 LFTQLFHSM--SIVFGDKFSEDFRIQFKTTIKDTANDNDITVKEN--------------- 255 Query: 499 KEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVK 558 E L + F G E+++ S A S+ Sbjct: 256 ---------------ESDSKLQCHISGTTNFMRNGLLEGLNEKIEK-RSDLTGANSIYSV 299 Query: 559 TTRFASFPDYLVIQIKKFTFGLDWVPK-KLDVSIEMPEELDISQLRGTGLQPGEEELPD 616 + + P +L +Q +F + K K+ + P +LD++ + + ++ D Sbjct: 300 EKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRD 358 Score = 37.0 bits (84), Expect = 0.039, Method: Composition-based stats. Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIK---KEGRWVIYNDQKVCASEK 842 Y L I+H G ++ GHY I+ E +W +ND KV EK Sbjct: 430 YNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEK 474 >1VJV-A nrPDB Length = 415 Score = 82.1 bits (201), Expect = 1e-15, Method: Composition-based stats. Identities = 53/299 (17%), Positives = 103/299 (34%), Gaps = 57/299 (19%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLL 385 G +N+GN+CYLN+ +Q L+ + D + ++ +P+Q S G Sbjct: 25 VGFKNMGNTCYLNATLQALYRVNDLRDMILN----------YNPSQGVSNS------GAQ 68 Query: 386 SGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFST-------NRQQDAQE 438 E K + Q + + P + + K +P+F+ +QQDA+E Sbjct: 69 DEEIHKQIVIEMKRCFENLQNKSFKSVLPVVLLNTLRKCYPQFAERDSQGGFYKQQDAEE 128 Query: 439 FFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALN 498 F L + + + + +E FR + IK A + + Sbjct: 129 LFTQLFHSM--SIVFGDKFSEDFRIQFKTTIKDTANDNDITVKEN--------------- 171 Query: 499 KEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVK 558 E L + F G E+++ S A S+ Sbjct: 172 ---------------ESDSKLQCHISGTTNFMRNGLLEGLNEKIEK-RSDLTGANSIYSV 215 Query: 559 TTRFASFPDYLVIQIKKFTFGLDWVPK-KLDVSIEMPEELDISQLRGTGLQPGEEELPD 616 + + P +L +Q +F + K K+ + P +LD++ + + ++ D Sbjct: 216 EKKISRLPKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRD 274 Score = 37.0 bits (84), Expect = 0.037, Method: Composition-based stats. Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 801 YQLFAFISHMGTSTMCGHYVCHIK---KEGRWVIYNDQKVCASEK 842 Y L I+H G ++ GHY I+ E +W +ND KV EK Sbjct: 346 YNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEK 390 >3JCR-V nrPDB Length = 565 Score = 80.2 bits (196), Expect = 4e-15, Method: Composition-based stats. Identities = 71/434 (16%), Positives = 145/434 (33%), Gaps = 84/434 (19%) Query: 217 ILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTIT----PDGADVYSYDEDDM--VLDP 270 ++CG+ YF G G +HA H + + + + L T+ PD ++ +D+ VL P Sbjct: 137 LVCGK-YFQGRGLKSHAYIHSVQFSHHVFLNLHTLKFYCLPDNYEIIDSSLEDITYVLKP 195 Query: 271 SLAEHLSHFGIDMLKMQKTDKTMTELEIDMNQRIGEWELIQESGVPLKPLFGPGYTGIRN 330 + + K+ + T L PG G+ N Sbjct: 196 TFTKQQIANLDKQAKLSRAYDGTTYL--------------------------PGIVGLNN 229 Query: 331 LGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHGLLSGEYS 390 + + Y N+V+Q L ++P + ++ E+ P D LL + Sbjct: 230 IKANDYANAVLQALSNVPPLRNYFL---EEDNYKNIKRPPGDIMF--------LLVQRFG 278 Query: 391 KPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERN 450 + + + + + + + + F +Q D +F +N + Sbjct: 279 ELMRKLWNPRNFKAHVSPHEMLQAVVLCSK-----KTFQITKQGDGVDFLSWFLNALHSA 333 Query: 451 CRSSENPN-----EVFRFLVE--------EKIKCLATEKVKYTQRVDYIMQLPVPMDAAL 497 ++ +VF+ + + E++ + M M L Sbjct: 334 LGGTKKKKKTIVTDVFQGSMRIFTKKLPHPDLPAEEKEQLLHNDEYQETMVESTFMYLTL 393 Query: 498 NKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAY-GAPEQVDDFWSTALQAKSVA 556 + Y+++K Q L+ QVP + L + G E+ + K Sbjct: 394 DLPTAPLYKDEKEQ----------LIIPQVPLFNILAKFNGITEKEYKTY------KENF 437 Query: 557 VKTTRFASFPDYLVIQIKKFTFGLDWVPKKLDVSIEMP-EELDISQLRGTGLQPGEEELP 615 +K + P YL+ IK+FT ++ +K + P +D+ + +Q + Sbjct: 438 LKRFQLTKLPPYLIFCIKRFT-KNNFFVEKNPTIVNFPITNVDLREYLSEEVQAVHK--- 493 Query: 616 DIAPPLVTPDEPKG 629 + L+ G Sbjct: 494 NTTYDLIANIVHDG 507 >6H4H-A nrPDB Length = 560 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 99/534 (18%), Positives = 175/534 (32%), Gaps = 88/534 (16%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKL--EKIFQNAPTDPTQDFSTQVAKLGH- 382 G++N+GN+C+ ++V+Q LF +P+F+R + + + +N + + + +L + Sbjct: 15 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYL 74 Query: 383 -GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFL 441 L+ G K V S + + KG S +QQD EF Sbjct: 75 FALMMGSNRKFVDPSAALDLL--------------------KGAFRSSEEQQQDVSEFTH 114 Query: 442 HLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 L++ +E + + N N R E + + L + Sbjct: 115 KLLDWLEDAFQLAVNVNSP-RNKSENPMVQ-------------------LFYGTFLTEGV 154 Query: 502 LLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTR 561 E K E P V CLE V+ S + Sbjct: 155 R---EGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDH---SVKYGQERW 208 Query: 562 FASFPDYLVIQIKKFTFGLD-WVPKKLDVSIEMPE--ELDISQLRGTGLQPGEEELPDIA 618 F P L ++ +F F P+K+ +E P+ +D R L + E Sbjct: 209 FTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRYMYRSKELIRNKRECIRKL 268 Query: 619 PPLVTPDEPKGSLGFYGNEDEDSFCSPHFS------SPTSPMLDESVIIQLVEMGFPMDA 672 + + K F P + T P + M P+ + Sbjct: 269 KEEIKILQQKLERYVKYGSGPARFPLPDMLKYVIEFASTKPASESCPPESDTHMTLPLSS 328 Query: 673 CRKAV---YYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVT 729 +V ++ E++ V S P+ + P P +S S + P P Sbjct: 329 VHCSVSDQTSKESTSTESSSQDVESTFSSPEDSLPKSKPLTSSRSSMEMPSQPAPRTVTD 388 Query: 730 TIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVP 789 ++ L+ R+ +E+ + D+ ++ E + Sbjct: 389 EEINF---VKTCLQRWRS---EIEQDIQ---------------DLKTCIASTTQTIEQMY 427 Query: 790 VGPKVRDGPGKYQLFAFISHMGTSTMCGHYVCHIKKEGR--WVIYNDQKVCASE 841 P +R P Y+L A + H G + GHY +I + R W+ YND V S Sbjct: 428 CDPLLRQVP--YRLHAVLVHDGQA-NAGHYWAYIYNQPRQSWLKYNDISVTESS 478 >1WGN-A nrPDB Length = 63 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 28/45 (62%) Query: 721 DPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSHIDD 765 P CV T+V+MG+S + L+A++ ++E+ +D++F+H Sbjct: 16 SPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAHSGP 60 >5JTV-A nrPDB Length = 594 Score = 72.5 bits (176), Expect = 7e-13, Method: Composition-based stats. Identities = 51/282 (18%), Positives = 94/282 (33%), Gaps = 60/282 (21%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 21 GYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE--------------- 57 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 + SK VP + Q + ++ K+ G + Q D QE L Sbjct: 58 --GDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSF---GWETLDSFMQHDVQELCRVL 112 Query: 444 INMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL 503 ++ VE + K C+ +P + Sbjct: 113 LDNVE----------------NKMKGTCVE-------------GTIPKLFRGKMVSYIQC 143 Query: 504 EYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAK--SVAVKTTR 561 + + + E+ + ++ + Y A EQ+D A K + Sbjct: 144 KEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVK 203 Query: 562 FASFPDYLVIQIKKFTFGLDW-VPKKLDVSIEMPEELDISQL 602 F + P L +Q+ +F + K++ E PE+L + + Sbjct: 204 FLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 245 >5JTJ-A nrPDB Length = 387 Score = 72.5 bits (176), Expect = 8e-13, Method: Composition-based stats. Identities = 51/282 (18%), Positives = 94/282 (33%), Gaps = 60/282 (21%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 21 GYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE--------------- 57 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 + SK VP + Q + ++ K+ G + Q D QE L Sbjct: 58 --GDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSF---GWETLDSFMQHDVQELCRVL 112 Query: 444 INMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL 503 ++ VE + K C+ +P + Sbjct: 113 LDNVE----------------NKMKGTCVE-------------GTIPKLFRGKMVSYIQC 143 Query: 504 EYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAK--SVAVKTTR 561 + + + E+ + ++ + Y A EQ+D A K + Sbjct: 144 KEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVK 203 Query: 562 FASFPDYLVIQIKKFTFGLDW-VPKKLDVSIEMPEELDISQL 602 F + P L +Q+ +F + K++ E PE+L + + Sbjct: 204 FLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 245 >2F1Z-A nrPDB Length = 522 Score = 72.1 bits (175), Expect = 9e-13, Method: Composition-based stats. Identities = 53/292 (18%), Positives = 96/292 (32%), Gaps = 60/292 (20%) Query: 314 GVPLKPLFGPGYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDF 373 GV GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 164 GVAWDSKKHTGYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE----- 210 Query: 374 STQVAKLGHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQ 433 + SK VP + Q + ++ K+ G + Q Sbjct: 211 ------------GDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSF---GWETLDSFMQ 255 Query: 434 QDAQEFFLHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPM 493 D QE L++ VE + K C+ +P Sbjct: 256 HDVQELCRVLLDNVE----------------NKMKGTCVE-------------GTIPKLF 286 Query: 494 DAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAK 553 + + + + E+ + ++ + Y A EQ+D Sbjct: 287 RGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEH 346 Query: 554 --SVAVKTTRFASFPDYLVIQIKKFTFGLDW-VPKKLDVSIEMPEELDISQL 602 A K +F + P L +Q+ +F + K++ E PE+L + + Sbjct: 347 GLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 398 >5J7T-A nrPDB Length = 671 Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 51/282 (18%), Positives = 94/282 (33%), Gaps = 60/282 (21%) Query: 324 GYTGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKLEKIFQNAPTDPTQDFSTQVAKLGHG 383 GY G++N G +CY+NS++Q LF + ++L K PT+ Sbjct: 2 GYVGLKNQGATCYMNSLLQTLF--------FTNQLRKAVYMMPTE--------------- 38 Query: 384 LLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHL 443 + SK VP + Q + ++ K+ G + Q D QE L Sbjct: 39 --GDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSF---GWETLDSFMQHDVQELCRVL 93 Query: 444 INMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELL 503 ++ VE + K C+ +P + Sbjct: 94 LDNVE----------------NKMKGTCVE-------------GTIPKLFRGKMVSYIQC 124 Query: 504 EYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAK--SVAVKTTR 561 + + + E+ + ++ + Y A EQ+D A K + Sbjct: 125 KEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVK 184 Query: 562 FASFPDYLVIQIKKFTFGLDW-VPKKLDVSIEMPEELDISQL 602 F + P L +Q+ +F + K++ E PE+L + + Sbjct: 185 FLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEF 226 >5O71-A nrPDB Length = 716 Score = 70.9 bits (172), Expect = 2e-12, Method: Composition-based stats. Identities = 96/535 (17%), Positives = 175/535 (32%), Gaps = 90/535 (16%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVD-----KLEKIFQNAPTDPTQDFSTQVAKL 380 G++N+GN+C+ ++V+Q LF++ +F+R ++ + + +N F ++ L Sbjct: 171 VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYL 230 Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440 L+ + P K +QQD EF Sbjct: 231 FALLVGTKRKYVDPSRAVEILKDAFKSNDS---------------------QQQDVSEFT 269 Query: 441 LHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKE 500 L++ +E + EEK K + + L Sbjct: 270 HKLLDWLEDAFQMKAEEE-----TDEEKPKNP---------------MVELFYGRFLAVG 309 Query: 501 ELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTT 560 L E KK + E P V CLEA +++ S Sbjct: 310 VL---EGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSENSGKSGQEH--- 363 Query: 561 RFASFPDYLVIQIKKFTFGLD-WVPKKLDVSIEMP--EELDISQLRGTG-LQPGEEELPD 616 F P L ++ +F F P+K+ +E P LD R + EE+ Sbjct: 364 WFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEIKR 423 Query: 617 IAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKA 676 + L + + + S P++D V+ +E C Sbjct: 424 LKDYLTVL-----------QQRLERYLSYGSGPKRFPLVD--VLQYALEFASSKPVCTSP 470 Query: 677 V--YYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSM 734 V + + + + + + A LP S+ P S +A + +++ Sbjct: 471 VDDIDASSPPSGSIPSQTLPSTTEQQGALSSELP-STSPSSVAAISS-------RSVIHK 522 Query: 735 GFSRDQA---LKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVG 791 F++ + L A + E + + S + E D + + + I ++ + Sbjct: 523 PFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIEL- 581 Query: 792 PKVRDGPG---KYQLFAFISHMGTSTMCGHYVCHI--KKEGRWVIYNDQKVCASE 841 D Y+L A + H G + GHY +I +E RW+ YND V S Sbjct: 582 -MYSDKSMIQVPYRLHAVLVHEGQA-NAGHYWAYIFDHRESRWMKYNDIAVTKSS 634 >6H4J-A nrPDB Length = 552 Score = 70.2 bits (170), Expect = 4e-12, Method: Composition-based stats. Identities = 96/535 (17%), Positives = 175/535 (32%), Gaps = 90/535 (16%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVD-----KLEKIFQNAPTDPTQDFSTQVAKL 380 G++N+GN+C+ ++V+Q LF++ +F+R ++ + + +N F ++ L Sbjct: 15 VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNYKPPSNAQDLPRNQKEHRNLPFMRELRYL 74 Query: 381 GHGLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFF 440 L+ + P K +QQD EF Sbjct: 75 FALLVGTKRKYVDPSRAVEILKDAFKSNDS---------------------QQQDVSEFT 113 Query: 441 LHLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKE 500 L++ +E + EEK K + + L Sbjct: 114 HKLLDWLEDAFQMKAEEE-----TDEEKPKNP---------------MVELFYGRFLAVG 153 Query: 501 ELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTT 560 L E KK + E P V CLEA +++ S Sbjct: 154 VL---EGKKFENTEMFGQYPLQVNGFKDLHECLEAAMIEGEIESLHSENSGKSGQEH--- 207 Query: 561 RFASFPDYLVIQIKKFTFGLD-WVPKKLDVSIEMP--EELDISQLRGTG-LQPGEEELPD 616 F P L ++ +F F P+K+ +E P LD R + EE+ Sbjct: 208 WFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDRYMHRNREITRIKREEIKR 267 Query: 617 IAPPLVTPDEPKGSLGFYGNEDEDSFCSPHFSSPTSPMLDESVIIQLVEMGFPMDACRKA 676 + L + + + S P++D V+ +E C Sbjct: 268 LKDYLTVL-----------QQRLERYLSYGSGPKRFPLVD--VLQYALEFASSKPVCTSP 314 Query: 677 V--YYTGNSGAEAAMNWVMSHMDDPDFANPLILPGSSGPGSTSAAADPPPEDCVTTIVSM 734 V + + + + + + A LP S+ P S +A + +++ Sbjct: 315 VDDIDASSPPSGSIPSQTLPSTTEQQGALSSELP-STSPSSVAAISS-------RSVIHK 366 Query: 735 GFSRDQA---LKALRATNNSLERAVDWIFSHIDDLDAEAAMDISEGRSAADSISESVPVG 791 F++ + L A + E + + S + E D + + + I ++ + Sbjct: 367 PFTQSRIPPDLPMHPAPRHITEEELSVLESCLHRWRTEIENDTRDLQESISRIHRTIEL- 425 Query: 792 PKVRDGPG---KYQLFAFISHMGTSTMCGHYVCHI--KKEGRWVIYNDQKVCASE 841 D Y+L A + H G + GHY +I +E RW+ YND V S Sbjct: 426 -MYSDKSMIQVPYRLHAVLVHEGQA-NAGHYWAYIFDHRESRWMKYNDIAVTKSS 478 >6HEH-A nrPDB Length = 382 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 58/312 (18%), Positives = 105/312 (33%), Gaps = 55/312 (17%) Query: 326 TGIRNLGNSCYLNSVVQVLFSIPDFQRKYVDKL--EKIFQNAPTDPTQDFSTQVAKLGH- 382 G++N+GN+C+ ++V+Q LF +P+F+R + + + +N + + + +L + Sbjct: 15 VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNVLENCRSHTEKRNIMFMQELQYL 74 Query: 383 -GLLSGEYSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFL 441 L+ G K V S + + KG S +QQD EF Sbjct: 75 FALMMGSNRKFVDPSAALDLL--------------------KGAFRSSEEQQQDVSEFTH 114 Query: 442 HLINMVERNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEE 501 L++ +E + + N N R E + + L + Sbjct: 115 KLLDWLEDAFQLAVNVNSP-RNKSENPMVQ-------------------LFYGTFLTEGV 154 Query: 502 LLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKTTR 561 E K E P V CLE V+ S + Sbjct: 155 R---EGKPFCNNETFGQYPLQVNGYRNLDECLEGAMVEGDVELLPSDH---SVKYGQERW 208 Query: 562 FASFPDYLVIQIKKFTFGLD-WVPKKLDVSIEMPEELDISQLRGTGLQPGEEELPDIAPP 620 F P L ++ +F F P+K+ +E P+ + + + G G ++P Sbjct: 209 FTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMDRYM-YGSGSGSRQVP---YR 264 Query: 621 LVTPDEPKGSLG 632 L +G Sbjct: 265 LHAVLVHEGQAN 276 >3C5K-A nrPDB Length = 109 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 10/100 (10%) Query: 192 IPPCGWK----CSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVK 247 IP G C C + W+ L+ + CGR N H ++H+ +G+PL + Sbjct: 16 IPAAGLDVTQPCGDCGTIQENWVCLSCYQVYCGRYI------NGHMLQHHGNSGHPLVLS 69 Query: 248 LGTITPDGADVYSYDEDDMVLDPSLAEHLSHFGIDMLKMQ 287 ++ +Y +LD H + FG DM Sbjct: 70 YIDLSAWCYYCQAYVHHQALLDVKNIAHQNKFGEDMPHPH 109 >5G0F-A nrPDB Length = 110 Score = 37.4 bits (85), Expect = 0.029, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 6/82 (7%) Query: 199 CSKCDMRENLWLNLTDGSILCGRRYFDGSGGNNHAVEHYRETGYPLAVKLGTITPDGADV 258 C +C W+ L +LCGR N H V H +E+G+P+ + ++ Sbjct: 28 CEECGGEAENWICLFCYKVLCGRYV------NQHMVTHGQESGHPVVLSFADLSVWCYAC 81 Query: 259 YSYDEDDMVLDPSLAEHLSHFG 280 SY + ++ + A HL FG Sbjct: 82 ESYVHNKVLHEAKNAAHLVKFG 103 >4I6Z-A nrPDB Length = 202 Score = 32.8 bits (73), Expect = 0.72, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 66/177 (37%), Gaps = 20/177 (11%) Query: 389 YSKPVPESGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVE 448 + K + + + E+ V G+ FK + + + ++ +EF L+ Sbjct: 18 FGKKGYDRATTDEIAEKAGVAKGLIFHYFKNKEELYYQAYMSVTEKLQKEFENFLM---- 73 Query: 449 RNCRSSENPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQLPVPMDAALNKEELLEYEEK 508 +N N +E I+ + + D+++ L V +D L K LL+ E+ Sbjct: 74 ------KNRNRDIFDFMERWIEKKLEYSASHPEEADFLITL-VSVDEGLRKRILLDLEKS 126 Query: 509 KRQA------EEEKMALPELVRAQVPFSSCLEAYGAPEQVDDFWSTALQAKSVAVKT 559 +R + + + L E V ++ + + E+V + Q K +K Sbjct: 127 QRVFFDFVREKLKDLDLAEDVTEEIALKFLMWFFSGFEEV---YLRTYQGKPELLKR 180 >3G25-A nrPDB Length = 501 Score = 32.4 bits (72), Expect = 0.85, Method: Composition-based stats. Identities = 20/134 (14%), Positives = 45/134 (33%), Gaps = 6/134 (4%) Query: 396 SGDGERVPEQKEVQDGIAPRMFKALIGKGHPEFSTNRQQDAQEFFLHLINMVERNCRSSE 455 + + QK G+A R FK P+ S + DA E + ++ ++ ++ Sbjct: 16 TSSRAILFNQKGEIAGVAQREFKQ----YFPQ-SGWVEHDANEIWTSVLAVMTEVINEND 70 Query: 456 NPNEVFRFLVEEKIKCLATEKVKYTQRVDYIMQL-PVPMDAALNKEELLEYEEKKRQAEE 514 + + + K+T R Y + ++ E + E+ + + Sbjct: 71 VRADQIAGIGITNQRETTVVWDKHTGRPIYHAIVWQSRQTQSICSELKQQGYEQTFRDKT 130 Query: 515 EKMALPELVRAQVP 528 + P +V Sbjct: 131 GLLLDPYFAGTKVK 144 >1DBH-A nrPDB Length = 354 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 8/80 (10%) Query: 489 LPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAY--------GAPE 540 L P+ L+ ELL+ E+K + +E+K L + + A + S +E E Sbjct: 146 LLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSE 205 Query: 541 QVDDFWSTALQAKSVAVKTT 560 F+S ++ K +A+K Sbjct: 206 SACRFYSQQMKGKQLAIKKM 225 >1XDV-A nrPDB Length = 847 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 36/80 (45%), Gaps = 8/80 (10%) Query: 489 LPVPMDAALNKEELLEYEEKKRQAEEEKMALPELVRAQVPFSSCLEAY--------GAPE 540 L P+ L+ ELL+ E+K + +E+K L + + A + S +E E Sbjct: 146 LLAPVYHCLHYFELLKQLEEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSE 205 Query: 541 QVDDFWSTALQAKSVAVKTT 560 F+S ++ K +A+K Sbjct: 206 SACRFYSQQMKGKQLAIKKM 225 >6QPR-A nrPDB Length = 361 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 15/91 (16%) Query: 126 PDYLEIARDGLGGLPDIVRDRVTSAVEALLSADSASRKQEVQAWDGEVRQ-VSKHAFSLK 184 P+ ++R+G LP V + A+ A DS VQA DG +R S+ L Sbjct: 58 PEAPAMSRNG--PLPSDVETKYGMALNATSYPDSV-----VQAMDGGIRAATSQEINELT 110 Query: 185 -----QLDNPAR--IPPCGWKCSKCDMRENL 208 ++ R IP W C CD E+L Sbjct: 111 YYTTLSANSYCRTVIPGATWDCIHCDATEDL 141 >4YIR-X nrPDB Length = 171 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 712 GPGSTSAAADPPPEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFS-HID 764 G GS P + ++ + +GF RD ++ A + + E A + +FS H D Sbjct: 118 GEGSFQVDYTPEDDQAISRLCELGFERDLVIQVYFACDKNEEAAANILFSDHAD 171 >5IEF-A nrPDB Length = 913 Score = 30.1 bits (66), Expect = 4.4, Method: Composition-based stats. Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 6/57 (10%) Query: 63 NKTGQRVYLHLRRTRRPKE-EDPATGTGDPPRKKPTRLAIGVEGGFDLSEEKFELDE 118 N G + H R R P+E +DPA G G P P G + ++EK E DE Sbjct: 139 NARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATP-----GDGDKPEETQEKAEKDE 190 >2OLM-A nrPDB Length = 140 Score = 29.3 bits (64), Expect = 7.9, Method: Composition-based stats. Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 15/61 (24%) Query: 159 SASRKQEVQAWDGEVRQVSKHAFSLKQLDNPARIPPCGWKCSKCDMRENLWLNLTDGSIL 218 SA RKQE KH L+ + P KC CD R ++N+T GS + Sbjct: 3 SAKRKQE-----------EKHLKMLRDMTG----LPHNRKCFDCDQRGPTYVNMTVGSFV 47 Query: 219 C 219 C Sbjct: 48 C 48 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.127 0.357 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,095,764 Number of Sequences: 36641 Number of extensions: 1520751 Number of successful extensions: 4065 Number of sequences better than 10.0: 43 Number of HSP's better than 10.0 without gapping: 69 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 3840 Number of HSP's gapped (non-prelim): 145 length of query: 858 length of database: 10,336,785 effective HSP length: 105 effective length of query: 753 effective length of database: 6,489,480 effective search space: 4886578440 effective search space used: 4886578440 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (29.0 bits)