BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P45470 (172 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1OI4-A nrPDB 347 1e-96 1G2I-A nrPDB 145 8e-36 3L18-A nrPDB 142 8e-35 2VRN-A nrPDB 119 5e-28 4OFW-A nrPDB 90 5e-19 4E08-A nrPDB 68 2e-12 1PDW-A nrPDB 49 1e-06 5SY4-A nrPDB 46 8e-06 3OT1-B nrPDB 45 2e-05 3MGK-A nrPDB 42 1e-04 4K2H-A nrPDB 38 0.003 2NV0-A nrPDB 37 0.005 1Q7R-A nrPDB 34 0.029 1OX5-A nrPDB 34 0.030 4WXY-B nrPDB 34 0.032 3NUL-A nrPDB 34 0.032 5EM0-A nrPDB 33 0.057 2ISS-D nrPDB 33 0.062 5NZC-A nrPDB 33 0.075 2YWB-A nrPDB 32 0.11 3FIJ-A nrPDB 32 0.13 4ESP-A nrPDB 32 0.16 5KXI-B nrPDB 32 0.20 3D54-D nrPDB 31 0.25 1G5U-A nrPDB 31 0.30 5FEF-A nrPDB 31 0.31 5FDS-A nrPDB 31 0.32 3KKL-A nrPDB 31 0.35 1KA9-H nrPDB 30 0.54 1K9V-F nrPDB 30 0.58 5EM1-A nrPDB 30 0.77 3CC1-A nrPDB 28 1.8 5W21-A nrPDB 28 1.9 2XHE-A nrPDB 28 2.0 3J2M-U nrPDB 28 2.3 4LRU-A nrPDB 28 2.7 3R75-A nrPDB 27 3.7 5ZRD-A nrPDB 27 6.4 3G7Q-A nrPDB 27 6.5 5VI4-B nrPDB 26 7.0 5JP0-A nrPDB 26 7.9 4NFY-A nrPDB 26 9.0 3KZ4-A nrPDB 26 9.2 6OJ5-A nrPDB 26 9.3 >1OI4-A nrPDB Length = 193 Score = 347 bits (891), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 171/172 (99%), Positives = 172/172 (100%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 +SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE Sbjct: 22 LSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 81 Query: 61 VTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRK 120 VTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRK Sbjct: 82 VTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRK 141 Query: 121 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 172 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA Sbjct: 142 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 193 >1G2I-A nrPDB Length = 166 Score = 145 bits (366), Expect = 8e-36, Method: Compositional matrix adjust. Identities = 79/167 (47%), Positives = 107/167 (64%), Gaps = 3/167 (1%) Query: 4 KIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTP 63 K+ L +EFED E P ++ GHEV + G T+ GK G SV +D + D+V P Sbjct: 2 KVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERG-TITGKHG-YSVKVDLTFDKVNP 59 Query: 64 AEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTA 123 EFDAL+LPGG +P+ +R + + V+ R + GKPV +ICHGPQ+LISA V+RGRK T+ Sbjct: 60 EEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTS 119 Query: 124 VKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 I D+ NAG E+ D EVVVD + V+SR P DL A+ RE ++LL Sbjct: 120 YPGIKDDMINAGVEWVDAEVVVDGN-WVSSRVPADLYAWMREFVKLL 165 >3L18-A nrPDB Length = 168 Score = 142 bits (358), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 81/169 (47%), Positives = 106/169 (62%), Gaps = 3/169 (1%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 S K+ L D FED E P ++ GHEV Q GK + GK G SV +D + +EV Sbjct: 2 SMKVLFLSADGFEDLELIYPLHRIKEEGHEVYVASFQRGK-ITGKHG-YSVNVDLTFEEV 59 Query: 62 TPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKL 121 P EFDAL+LPGG +P+ +R + + V TR KPV +ICHGPQ+LISA V++GR+ Sbjct: 60 DPDEFDALVLPGGKAPEIVRLNEKAVMITRRMFEDDKPVASICHGPQILISAKVLKGRRG 119 Query: 122 TAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 T+ I DV NAGAE+ D EVVVD + V+SR P DL A+ RE ++LL Sbjct: 120 TSTITIRDDVINAGAEWIDAEVVVDGN-WVSSRHPGDLYAWMREFVKLL 167 >2VRN-A nrPDB Length = 190 Score = 119 bits (299), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 68/167 (40%), Positives = 102/167 (61%), Gaps = 5/167 (2%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGH--EVITIEKQAGKTVKGK-KGEASVTIDKSID 59 KKIA+L D E+ E TSP AG E+I++E +++KG + + +D + Sbjct: 10 KKIAILAADGVEEIELTSPRAAIEAAGGTTELISLEPGEIQSMKGDIEPQEKYRVDHVVS 69 Query: 60 EVTPAEFDALLLPGGH-SPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRG 118 EV +++D LLLPGG +PD LR + + F RD ++GKP+ AICHGP L + +G Sbjct: 70 EVQVSDYDGLLLPGGTVNPDKLRLEEGAMKFVRDMYDAGKPIAAICHGPWSLSETGIAQG 129 Query: 119 RKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNRE 165 K+T+ + ++ AGA++ D+E V DK +VTSR PDDLPAFN++ Sbjct: 130 LKMTSWSSLKRELTLAGAQWVDEECVTDKG-VVTSRKPDDLPAFNKK 175 >4OFW-A nrPDB Length = 387 Score = 90.1 bits (222), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 56/188 (29%), Positives = 93/188 (49%), Gaps = 19/188 (10%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEV--ITIEKQAG-------------KTVKGK 46 +K+I L D ED E P + G +V + EK+AG +T K Sbjct: 195 NKRILFLCGDYMEDYEVKVPFQSLQALGCQVDAVCPEKKAGERCPTAIHDFEGDQTYSEK 254 Query: 47 KGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHG 106 G + + + D++ + +DAL++PGG +P+YL + + ++F+NS KPV +ICHG Sbjct: 255 PGH-TFALTTNFDDLVSSSYDALVIPGGRAPEYLALNEHVLNIVKEFMNSEKPVASICHG 313 Query: 107 PQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVV---VDKDQLVTSRTPDDLPAFN 163 Q+L +A V++GRK TA + ++V G + + + + LVT P F Sbjct: 314 QQILAAAGVLKGRKCTAYPAVKLNVVLGGGTWLEPDPIDRCFTDGNLVTGAAWPGHPEFV 373 Query: 164 REALRLLG 171 + + LLG Sbjct: 374 SQLMALLG 381 Score = 85.9 bits (211), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 57/189 (30%), Positives = 95/189 (50%), Gaps = 19/189 (10%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITI--EKQAG-------------KTVKGK 46 S+ + +L D ED E P + G V T+ K+AG +T Sbjct: 2 SRTVLILCGDYMEDYEVMVPFQALQAFGITVHTVCPGKKAGDSCPTAVHDFCGHQTYFES 61 Query: 47 KGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHG 106 +G + T++ + DEV +++D L++PGG +P+YL V ++F SGKP+ +ICHG Sbjct: 62 RGH-NFTLNATFDEVDLSKYDGLVIPGGRAPEYLALTASVVELVKEFSRSGKPIASICHG 120 Query: 107 PQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYD---QEVVVDKDQLVTSRTPDDLPAFN 163 +L +AD + GRK TA + + AGA++ + +V V L+T+ T + P F Sbjct: 121 QLILAAADTVNGRKCTAYATVGPSLVAAGAKWVEPITPDVCVVDGSLITAATYEGHPEFI 180 Query: 164 REALRLLGA 172 + ++ LG Sbjct: 181 QLFVKALGG 189 >4E08-A nrPDB Length = 190 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 9/160 (5%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 MSK V++ E+ EF AD R+AG +V G+ VK + + + D S+ + Sbjct: 4 MSKSALVILAPGAEEMEFIIAADVLRRAGIKVTVAGLNGGEAVKCSR-DVQILPDTSLAQ 62 Query: 61 VTPAEFDALLLPGGHSPDYLRGDNRFVT-FTRDFVNSGKPVFAICHGPQLLISADVIRGR 119 V +FD ++LPGG G++ V R + G + AIC P +L V G+ Sbjct: 63 VASDKFDVVVLPGGLGGSNAMGESSLVGDLLRSQESGGGLIAAICAAPTVLAKHGVASGK 122 Query: 120 KLT---AVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTP 156 LT ++KP +++ + D + VV L+TSR P Sbjct: 123 SLTSYPSMKPQLVN----NYSYVDDKTVVKDGNLITSRGP 158 >1PDW-A nrPDB Length = 197 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 5/158 (3%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 SK+ V++ E+ E P D R+AG +V T+ AGK + + D S+++ Sbjct: 3 SKRALVILAKGAEEMETVIPVDVMRRAGIKV-TVAGLAGKDPVQCSRDVVICPDASLEDA 61 Query: 62 TP-AEFDALLLPGGH-SPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGR 119 +D ++LPGG+ L ++ N + AIC GP L++ ++ G Sbjct: 62 KKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGS 121 Query: 120 KLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLV-TSRTP 156 K+T P+ D G + E V+KD L+ TSR P Sbjct: 122 KVT-THPLAKDKMMNGGHYTYSENRVEKDGLILTSRGP 158 >5SY4-A nrPDB Length = 199 Score = 46.2 bits (108), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 46/175 (26%), Positives = 77/175 (44%), Gaps = 8/175 (4%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVIT--IEKQAGKTVKGKKGEASVTIDKSI 58 MS V + E++E + D + G +V T + + +G + D + Sbjct: 4 MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLAITCSRG-VKLLADAPL 62 Query: 59 DEVTPAEFDALLLPGG-HSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGP-QLLISADVI 116 EV E+D ++LPGG + R V + F SG+ V AIC P +L+ D+ Sbjct: 63 VEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAAICAAPATVLVPHDIF 122 Query: 117 RGRKLTAVKPIIIDVKNAGAEFYDQEVVVD-KDQLVTSRTPDDLPAFNREALRLL 170 +T P + D K ++ D+ VV D + +L+TS+ P F + + LL Sbjct: 123 PIGNMTGF-PTLKD-KIPAEQWLDKRVVWDARVKLLTSQGPGTAIDFGLKIIDLL 175 >3OT1-B nrPDB Length = 208 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 2/113 (1%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 MSK+I V + E+ E D +AG +V V+G +G +T +++++ Sbjct: 8 MSKRILVPVAHGSEEMETVIIVDTLVRAGFQVTMAAVGDKLQVQGSRG-VWLTAEQTLEA 66 Query: 61 VTPAEFDALLLPGGHSPDYLRGDNR-FVTFTRDFVNSGKPVFAICHGPQLLIS 112 + FDAL LPGG D+ + F GK V AIC P L+ + Sbjct: 67 CSAEAFDALALPGGVGGAQAFADSTALLALIDAFSQQGKLVAAICATPALVFA 119 >3MGK-A nrPDB Length = 211 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 31/130 (23%), Positives = 59/130 (45%), Gaps = 12/130 (9%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEF--RKAGHEVITIEKQAGKTVKGKKGEASVTI---D 55 +S +I VL+ ++FE + P + F + E+ I G +K ++ D Sbjct: 3 LSYRIDVLLFNKFETLDVFGPVEIFGNLQDDFELNFISSDGGLVESSQKVRVETSLYTRD 62 Query: 56 KSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADV 115 ++I+++ L +PGG D+ F+ F + V K + ++C G LL A + Sbjct: 63 ENIEKI-------LFVPGGSGTREKVNDDNFINFIGNMVKESKYIISVCTGSALLSKAGI 115 Query: 116 IRGRKLTAVK 125 + G++ T K Sbjct: 116 LNGKRATTNK 125 >4K2H-A nrPDB Length = 188 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 31/120 (25%), Positives = 55/120 (45%), Gaps = 3/120 (2%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVT 62 KK+AVL+ FE++E D R+ +V T+ + V + + D ++ E Sbjct: 5 KKVAVLLAPGFEEAEAIVTLDILRRLHIDVETLACAESRAVVSYH-DIPMVADSTLSERQ 63 Query: 63 PAEFDALLLPGG-HSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISAD-VIRGRK 120 A FDA++LPGG L + + F +GK + I ++ A +++GR+ Sbjct: 64 QALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPIASAAARVLGAHGLLKGRR 123 >2NV0-A nrPDB Length = 196 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 4/56 (7%) Query: 65 EFDALLLPGGHSPDYLR--GDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRG 118 E D L+LPGG S R +F+ R+F GKP+F C G L+I A I G Sbjct: 38 EVDGLILPGGESTTMRRLIDTYQFMEPLREFAAQGKPMFGTCAG--LIILAKEIAG 91 >1Q7R-A nrPDB Length = 219 Score = 34.3 bits (77), Expect = 0.029, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 66 FDALLLPGGHSPDYLRGDNRFVTF--TRDFVNSGKPVFAICHGPQLL 110 D L+LPGG S R +R+ + F +GKP+F C G LL Sbjct: 61 LDGLVLPGGESTTMRRLIDRYGLMEPLKQFAAAGKPMFGTCAGLILL 107 >1OX5-A nrPDB Length = 555 Score = 34.3 bits (77), Expect = 0.030, Method: Compositional matrix adjust. Identities = 22/53 (41%), Positives = 28/53 (52%), Gaps = 9/53 (16%) Query: 69 LLLPG----GHSPDYL--RGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADV 115 L+LPG GH D L RG F R+++ SGKP+ IC G Q L + V Sbjct: 48 LILPGVGNYGHFVDNLFNRG---FEKPIREYIESGKPIMGICVGLQALFAGSV 97 >4WXY-B nrPDB Length = 228 Score = 33.9 bits (76), Expect = 0.032, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%) Query: 66 FDALLLPGGHSPDYLRGDNRFVTF--TRDFVNSGKPVFAICHGPQLL 110 D L+LPGG S R +R+ + F +GKP+F C G LL Sbjct: 70 LDGLVLPGGESTTMRRLIDRYGLMEPLKQFAAAGKPMFGTCAGLILL 116 >3NUL-A nrPDB Length = 130 Score = 33.9 bits (76), Expect = 0.032, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 9 ITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKS 57 I +FE+ F +P F G + + I+ + G ++GKKG VTI K+ Sbjct: 49 IKKDFEEPGFLAPTGLFL-GGEKYMVIQGEQGAVIRGKKGPGGVTIKKT 96 >5EM0-A nrPDB Length = 135 Score = 33.1 bits (74), Expect = 0.057, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 9 ITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDA 68 I EF ++ +P F G + + I+ +AG ++GKKG + I K+ + +D Sbjct: 54 IIKEFNEAGQLAPTGLFL-GGAKYMVIQGEAGAVIRGKKGAGGICIKKTGQAMVFGIYDE 112 Query: 69 LLLPG 73 + PG Sbjct: 113 PVAPG 117 >2ISS-D nrPDB Length = 208 Score = 33.1 bits (74), Expect = 0.062, Method: Compositional matrix adjust. Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 10/50 (20%) Query: 67 DALLLPGGHSPDYLR------GDNRFVTFTRDFVNSGKPVFAICHGPQLL 110 D L+LPGG S +R D + V + +N+G PVFA C G LL Sbjct: 59 DGLILPGGESTTMIRILKEMDMDEKLV----ERINNGLPVFATCAGVILL 104 >5NZC-A nrPDB Length = 132 Score = 32.7 bits (73), Expect = 0.075, Method: Compositional matrix adjust. Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 11/73 (15%) Query: 12 EFEDSEFTSPADEFRKAGH-----------EVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 +F+ E T +F + GH + + I+ +AG ++GKKG +TI K+ Sbjct: 42 QFKPQEITGIMKDFEEPGHLAPTGLHLGGIKYMVIQGEAGAVIRGKKGSGGITIKKTGQA 101 Query: 61 VTPAEFDALLLPG 73 + ++ + PG Sbjct: 102 LVFGIYEEPVTPG 114 >2YWB-A nrPDB Length = 503 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 28/60 (46%), Gaps = 11/60 (18%) Query: 55 DKSIDEVTPAEFDALLLPGG----HSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLL 110 D ++EV AL+L GG PD R D R + SG P+ IC+G QLL Sbjct: 32 DAPLEEVLKHRPQALILSGGPRSVFDPDAPRPDPRLFS-------SGLPLLGICYGMQLL 84 >3FIJ-A nrPDB Length = 254 Score = 32.0 bits (71), Expect = 0.13, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 83 DNRFVTFTRDFVNSGKPVFAICHGPQLL 110 D+ + R +++GKP+FAIC G QL+ Sbjct: 94 DSYEIALVRAALDAGKPIFAICRGMQLV 121 >4ESP-A nrPDB Length = 130 Score = 32.0 bits (71), Expect = 0.16, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 1/65 (1%) Query: 9 ITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDA 68 I ++F + +P + G + + I+ + G ++GKKG VTI K+ + +D Sbjct: 49 IMNDFAEPGSLAPTGLYL-GGTKYMVIQGEPGTVIRGKKGPGGVTIKKTNQALIIGIYDE 107 Query: 69 LLLPG 73 + PG Sbjct: 108 PMTPG 112 >5KXI-B nrPDB Length = 403 Score = 31.6 bits (70), Expect = 0.20, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 29/48 (60%), Gaps = 7/48 (14%) Query: 57 SIDEVTPA-EFDALLLPG--GHSPDYLRGDNRFVTFTRDFVNSGKPVF 101 S+D+ TP+ E+D + LPG +PD D+ +V T DF+ KP+F Sbjct: 168 SLDDFTPSGEWDIVALPGRRNENPD----DSTYVDITYDFIIRRKPLF 211 >3D54-D nrPDB Length = 213 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 11/78 (14%) Query: 50 ASVTIDKSIDEVTPAEFDALLLPGGHS-PDYLR-----GDNRFVTFTRDFVNSGKPVFAI 103 + V +D +D+ ++ ++LPGG S DYLR + GK + I Sbjct: 31 SYVGLDDKLDD-----YELIILPGGFSYGDYLRPGAVAAREKIAFEIAKAAERGKLIMGI 85 Query: 104 CHGPQLLISADVIRGRKL 121 C+G Q+LI +++G L Sbjct: 86 CNGFQILIEMGLLKGALL 103 >1G5U-A nrPDB Length = 131 Score = 30.8 bits (68), Expect = 0.30, Method: Compositional matrix adjust. Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 2/72 (2%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 S ++A ++ D F++ +P G + + I+ + G ++GKKG +T+ ++ + Sbjct: 44 SDEVAAVMKD-FDEPGSLAPTG-LHLGGTKYMVIQGEPGAVIRGKKGSGGITVKRTGQAL 101 Query: 62 TPAEFDALLLPG 73 +D L PG Sbjct: 102 IIGIYDEPLTPG 113 >5FEF-A nrPDB Length = 132 Score = 30.8 bits (68), Expect = 0.31, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVT 62 +++A +I D F++ +P F G + + I+ + G ++GKKG +TI K+ + Sbjct: 46 EEVAGMIKD-FDEPGTLAPTGLFV-GGTKYMVIQGEPGVVIRGKKGTGGITIKKTGMSLI 103 Query: 63 PAEFDALLLPG 73 +D + PG Sbjct: 104 IGIYDEPMTPG 114 >5FDS-A nrPDB Length = 131 Score = 30.8 bits (68), Expect = 0.32, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 S++I +++D F + +P + G + + I+ + G ++GKKG VT+ K+ + Sbjct: 44 SEEITGIMSD-FHEPGTLAPTGLYI-GGTKYMVIQGEPGAVIRGKKGPGGVTVKKTNQAL 101 Query: 62 TPAEFDALLLPG 73 +D + PG Sbjct: 102 IIGIYDEPMTPG 113 >3KKL-A nrPDB Length = 244 Score = 30.8 bits (68), Expect = 0.35, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 3/57 (5%) Query: 56 KSIDEVTPAEFDALLLPGGHSP--DYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLL 110 K+ +EV +++ GH DY + N ++ + N G + AICHGP L Sbjct: 89 KTANEVNASDYKVFFASAGHGALFDYPKAKNLQDIASKIYANGG-VIAAICHGPLLF 144 >1KA9-H nrPDB Length = 200 Score = 30.0 bits (66), Expect = 0.54, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 3/68 (4%) Query: 50 ASVTIDKSIDEVTPAEFDALLLPG-GHSPDYLRG--DNRFVTFTRDFVNSGKPVFAICHG 106 A ++ + D E D L+LPG GH +R ++ FV R + G P IC G Sbjct: 25 AGFSVAVAQDPKAHEEADLLVLPGQGHFGQVMRAFQESGFVERVRRHLERGLPFLGICVG 84 Query: 107 PQLLISAD 114 Q+L Sbjct: 85 MQVLYEGS 92 >1K9V-F nrPDB Length = 201 Score = 30.0 bits (66), Expect = 0.58, Method: Compositional matrix adjust. Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%) Query: 66 FDALLLPG-GHSPDYLRG--DNRFVTFTRDFVNSGKPVFAICHGPQLL 110 +D L +PG GH + +R +N + F R V + V +C G QLL Sbjct: 43 YDLLFIPGVGHFGEGMRRLRENDLIDFVRKHVEDERYVVGVCLGMQLL 90 >5EM1-A nrPDB Length = 135 Score = 29.6 bits (65), Expect = 0.77, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 1/65 (1%) Query: 9 ITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDA 68 I EF + +P F AG + + I+ + G ++GKKG + I K+ + ++ Sbjct: 54 IIKEFSEPGALAPTGLFL-AGAKYMVIQGEPGAVIRGKKGAGGICIKKTGQAMVFGIYEE 112 Query: 69 LLLPG 73 + PG Sbjct: 113 PVNPG 117 >3CC1-A nrPDB Length = 433 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 5/48 (10%) Query: 67 DALLLPGGH----SPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLL 110 D +LP GH S D GD R+ FT+D + ++AICH P + Sbjct: 271 DCGMLPLGHIGIRSVDGPGGD-RWTRFTKDEQLTMMNLWAICHSPLMF 317 >5W21-A nrPDB Length = 981 Score = 28.1 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 17/33 (51%), Gaps = 7/33 (21%) Query: 77 PDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQL 109 PD+ + +F+ T DF FA+C GP L Sbjct: 350 PDFTESEKKFIKGTADF-------FALCFGPTL 375 >2XHE-A nrPDB Length = 650 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 1/42 (2%) Query: 18 FTSPADEFRKAGHEVITIEKQAGKTVKGKKGE-ASVTIDKSI 58 F+S D KA ++T E+Q G V+ GE ASV +D+ + Sbjct: 358 FSSTIDSCTKAEQNIVTEEEQDGNKVRDFIGEVASVVVDRRV 399 >3J2M-U nrPDB Length = 659 Score = 27.7 bits (60), Expect = 2.3, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 2/52 (3%) Query: 95 NSGKPVFAICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVD 146 ++ K VF +GPQ +I R V+ +++ K G + YD + +D Sbjct: 263 STAKAVFG--YGPQTDSQYAIIVRRNDAIVQSVVLSTKRGGKDIYDSNIYID 312 >4LRU-A nrPDB Length = 239 Score = 27.7 bits (60), Expect = 2.7, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 37/87 (42%), Gaps = 14/87 (16%) Query: 56 KSIDEVTPAEFDALLLPGGHSP--DYLRGDN--RFVTFTRDFVNSGKPVFAICHGPQLLI 111 K ++ P ++D GH DY + + T D G V A+CHGP + Sbjct: 90 KKASDLDPNDYDIFFGSAGHGTLFDYPNAKDLQKIATTVYD---KGGVVSAVCHGPAIFE 146 Query: 112 SAD-------VIRGRKLTAVKPIIIDV 131 + + +I+G+K+T I D+ Sbjct: 147 NLNDPKTGEPLIKGKKITGFTDIGEDI 173 >3R75-A nrPDB Length = 645 Score = 27.3 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 3/55 (5%) Query: 59 DEVTPAEFDALLLPGGHSPDYLRGD---NRFVTFTRDFVNSGKPVFAICHGPQLL 110 D V A +D +++ G GD R + R ++ GKP A+C Q+L Sbjct: 480 DAVDLARYDVVVMGPGPGDPSDAGDPRIARLYAWLRHLIDEGKPFMAVCLSHQIL 534 >5ZRD-A nrPDB Length = 549 Score = 26.6 bits (57), Expect = 6.4, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 16/69 (23%) Query: 14 EDSEFTSPADEFRKAGHE------VITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFD 67 E T+P + F+KA E I IE+Q G T S+D+ TP Sbjct: 365 ESLNLTTPLNPFKKASGEAYTSEDCINIERQLGFTYG----------PGSLDDATPELKS 414 Query: 68 ALLLPGGHS 76 L +P G+S Sbjct: 415 LLAVPSGNS 423 >3G7Q-A nrPDB Length = 417 Score = 26.6 bits (57), Expect = 6.5, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 68 ALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICH--GPQ 108 A++L GG+ + F T D V SGK A+C+ GPQ Sbjct: 33 AIMLGGGNPAHIPAMQDYFQTLLTDMVESGKAADALCNYDGPQ 75 >5VI4-B nrPDB Length = 309 Score = 26.2 bits (56), Expect = 7.0, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 22/45 (48%) Query: 25 FRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDAL 69 F K H + + Q KTV G GEA + ++ +E + + D L Sbjct: 221 FGKGSHFLADVLWQINKTVVGNFGEARIQEEEGRNESSSNDMDCL 265 >5JP0-A nrPDB Length = 772 Score = 26.2 bits (56), Expect = 7.9, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 21/41 (51%) Query: 129 IDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRL 169 +DV N G + V++ LV S TPD++ N E + L Sbjct: 662 VDVTNTGKVAGKESVLLFSKDLVASSTPDNIRLRNFEKVSL 702 >4NFY-A nrPDB Length = 307 Score = 25.8 bits (55), Expect = 9.0, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 19/38 (50%) Query: 4 KIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGK 41 KI V+ F ++ + KAGHEV+ IEK K Sbjct: 2 KIVVITEKPFAENAVKGIREILEKAGHEVVMIEKYKKK 39 >3KZ4-A nrPDB Length = 880 Score = 25.8 bits (55), Expect = 9.2, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 111 ISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRT 155 + A +++ RK+ +KPI+ + + +FY +V + D + TS T Sbjct: 782 VFAQIVKLRKVDTLKPILYKINSDSNDFY---LVANYDWVPTSTT 823 >6OJ5-A nrPDB Length = 887 Score = 25.8 bits (55), Expect = 9.3, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 26/45 (57%), Gaps = 3/45 (6%) Query: 111 ISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRT 155 + A +++ RK+ +KPI+ + + +FY +V + D + TS T Sbjct: 789 VFAQIVKLRKVDTLKPILYKINSDSNDFY---LVANYDWVPTSTT 830 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1OI4-A nrPDB 240 2e-64 1G2I-A nrPDB 210 3e-55 3L18-A nrPDB 209 3e-55 4OFW-A nrPDB 185 8e-48 2VRN-A nrPDB 176 4e-45 4E08-A nrPDB 167 2e-42 5SY4-A nrPDB 161 1e-40 1PDW-A nrPDB 155 8e-39 3OT1-B nrPDB 134 3e-32 3MGK-A nrPDB 128 1e-30 Sequences not found previously or not previously below threshold: 4K2H-A nrPDB 90 6e-19 4GE0-A nrPDB 80 5e-16 3F5D-A nrPDB 55 2e-08 4D1Y-A nrPDB 49 1e-06 3CNE-A nrPDB 49 2e-06 1OY1-A nrPDB 42 1e-04 4LRU-A nrPDB 41 2e-04 1K9V-F nrPDB 41 3e-04 5JZM-A nrPDB 40 4e-04 2NV0-A nrPDB 39 9e-04 3KKL-A nrPDB 39 0.001 5XR3-A nrPDB 38 0.003 1Q7R-A nrPDB 37 0.003 4WXY-B nrPDB 37 0.003 3D54-D nrPDB 37 0.003 1QVW-A nrPDB 37 0.003 1N57-A nrPDB 37 0.004 1SY7-A nrPDB 37 0.006 1OX5-A nrPDB 36 0.009 1KA9-H nrPDB 35 0.020 1F4U-A nrPDB 32 0.098 4GUD-A nrPDB 32 0.11 3R75-A nrPDB 32 0.13 2ISS-D nrPDB 32 0.16 4BIM-A nrPDB 31 0.29 4NFY-A nrPDB 30 0.37 1UE8-A nrPDB 30 0.39 3FIJ-A nrPDB 30 0.53 4WEA-A nrPDB 30 0.71 6BKP-A nrPDB 29 1.0 6BKN-A nrPDB 29 1.2 2YWB-A nrPDB 29 1.2 6FQB-E nrPDB 29 1.6 3G7Q-A nrPDB 28 2.2 4Z6K-A nrPDB 28 2.6 4M4V-A nrPDB 27 3.2 5EM0-A nrPDB 27 3.5 4BI9-A nrPDB 27 3.8 5NZC-A nrPDB 27 4.9 >1OI4-A nrPDB Length = 193 Score = 240 bits (613), Expect = 2e-64, Method: Composition-based stats. Identities = 171/172 (99%), Positives = 172/172 (100%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 +SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE Sbjct: 22 LSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 81 Query: 61 VTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRK 120 VTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRK Sbjct: 82 VTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRK 141 Query: 121 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 172 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA Sbjct: 142 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 193 >1G2I-A nrPDB Length = 166 Score = 210 bits (534), Expect = 3e-55, Method: Composition-based stats. Identities = 79/168 (47%), Positives = 106/168 (63%), Gaps = 3/168 (1%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVT 62 K+ L +EFED E P ++ GHEV + G T+ GK G SV +D + D+V Sbjct: 1 MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERG-TITGKHG-YSVKVDLTFDKVN 58 Query: 63 PAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLT 122 P EFDAL+LPGG +P+ +R + + V+ R + GKPV +ICHGPQ+LISA V+RGRK T Sbjct: 59 PEEFDALVLPGGRAPERVRLNEKAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGT 118 Query: 123 AVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 + I D+ NAG E+ D EVVVD V+SR P DL A+ RE ++LL Sbjct: 119 SYPGIKDDMINAGVEWVDAEVVVD-GNWVSSRVPADLYAWMREFVKLL 165 >3L18-A nrPDB Length = 168 Score = 209 bits (533), Expect = 3e-55, Method: Composition-based stats. Identities = 81/169 (47%), Positives = 105/169 (62%), Gaps = 3/169 (1%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 S K+ L D FED E P ++ GHEV Q GK + GK G SV +D + +EV Sbjct: 2 SMKVLFLSADGFEDLELIYPLHRIKEEGHEVYVASFQRGK-ITGKHG-YSVNVDLTFEEV 59 Query: 62 TPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKL 121 P EFDAL+LPGG +P+ +R + + V TR KPV +ICHGPQ+LISA V++GR+ Sbjct: 60 DPDEFDALVLPGGKAPEIVRLNEKAVMITRRMFEDDKPVASICHGPQILISAKVLKGRRG 119 Query: 122 TAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 T+ I DV NAGAE+ D EVVVD V+SR P DL A+ RE ++LL Sbjct: 120 TSTITIRDDVINAGAEWIDAEVVVD-GNWVSSRHPGDLYAWMREFVKLL 167 >4OFW-A nrPDB Length = 387 Score = 185 bits (470), Expect = 8e-48, Method: Composition-based stats. Identities = 56/188 (29%), Positives = 93/188 (49%), Gaps = 19/188 (10%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEV--ITIEKQAG-------------KTVKGK 46 +K+I L D ED E P + G +V + EK+AG +T K Sbjct: 195 NKRILFLCGDYMEDYEVKVPFQSLQALGCQVDAVCPEKKAGERCPTAIHDFEGDQTYSEK 254 Query: 47 KGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHG 106 G + + + D++ + +DAL++PGG +P+YL + + ++F+NS KPV +ICHG Sbjct: 255 PGH-TFALTTNFDDLVSSSYDALVIPGGRAPEYLALNEHVLNIVKEFMNSEKPVASICHG 313 Query: 107 PQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVV---VDKDQLVTSRTPDDLPAFN 163 Q+L +A V++GRK TA + ++V G + + + + LVT P F Sbjct: 314 QQILAAAGVLKGRKCTAYPAVKLNVVLGGGTWLEPDPIDRCFTDGNLVTGAAWPGHPEFV 373 Query: 164 REALRLLG 171 + + LLG Sbjct: 374 SQLMALLG 381 Score = 146 bits (368), Expect = 5e-36, Method: Composition-based stats. Identities = 54/189 (28%), Positives = 91/189 (48%), Gaps = 19/189 (10%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQ---------------AGKTVKGK 46 S+ + +L D ED E P + G V T+ +T Sbjct: 2 SRTVLILCGDYMEDYEVMVPFQALQAFGITVHTVCPGKKAGDSCPTAVHDFCGHQTYFES 61 Query: 47 KGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHG 106 +G + T++ + DEV +++D L++PGG +P+YL V ++F SGKP+ +ICHG Sbjct: 62 RGH-NFTLNATFDEVDLSKYDGLVIPGGRAPEYLALTASVVELVKEFSRSGKPIASICHG 120 Query: 107 PQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYD---QEVVVDKDQLVTSRTPDDLPAFN 163 +L +AD + GRK TA + + AGA++ + +V V L+T+ T + P F Sbjct: 121 QLILAAADTVNGRKCTAYATVGPSLVAAGAKWVEPITPDVCVVDGSLITAATYEGHPEFI 180 Query: 164 REALRLLGA 172 + ++ LG Sbjct: 181 QLFVKALGG 189 >2VRN-A nrPDB Length = 190 Score = 176 bits (446), Expect = 4e-45, Method: Composition-based stats. Identities = 68/170 (40%), Positives = 103/170 (60%), Gaps = 5/170 (2%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGH--EVITIEKQAGKTVKGK-KGEASVTIDKSID 59 KKIA+L D E+ E TSP AG E+I++E +++KG + + +D + Sbjct: 10 KKIAILAADGVEEIELTSPRAAIEAAGGTTELISLEPGEIQSMKGDIEPQEKYRVDHVVS 69 Query: 60 EVTPAEFDALLLPGGH-SPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRG 118 EV +++D LLLPGG +PD LR + + F RD ++GKP+ AICHGP L + +G Sbjct: 70 EVQVSDYDGLLLPGGTVNPDKLRLEEGAMKFVRDMYDAGKPIAAICHGPWSLSETGIAQG 129 Query: 119 RKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALR 168 K+T+ + ++ AGA++ D+E V DK +VTSR PDDLPAFN++ + Sbjct: 130 LKMTSWSSLKRELTLAGAQWVDEECVTDKG-VVTSRKPDDLPAFNKKIVE 178 >4E08-A nrPDB Length = 190 Score = 167 bits (422), Expect = 2e-42, Method: Composition-based stats. Identities = 49/173 (28%), Positives = 76/173 (43%), Gaps = 3/173 (1%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 MSK V++ E+ EF AD R+AG +V G+ VK + + + D S+ + Sbjct: 4 MSKSALVILAPGAEEMEFIIAADVLRRAGIKVTVAGLNGGEAVKCSR-DVQILPDTSLAQ 62 Query: 61 VTPAEFDALLLPGGHSPDYLRGDNRFVT-FTRDFVNSGKPVFAICHGPQLLISADVIRGR 119 V +FD ++LPGG G++ V R + G + AIC P +L V G+ Sbjct: 63 VASDKFDVVVLPGGLGGSNAMGESSLVGDLLRSQESGGGLIAAICAAPTVLAKHGVASGK 122 Query: 120 KLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 172 LT+ + + N + D + VV L+TSR P F + L Sbjct: 123 SLTSYPSMKPQLVN-NYSYVDDKTVVKDGNLITSRGPGTAYEFALKIAEELAG 174 >5SY4-A nrPDB Length = 199 Score = 161 bits (408), Expect = 1e-40, Method: Composition-based stats. Identities = 44/177 (24%), Positives = 74/177 (41%), Gaps = 8/177 (4%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIE--KQAGKTVKGKKGEASVTIDKSI 58 MS V + E++E + D + G +V T + +G + D + Sbjct: 4 MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLAITCSRG-VKLLADAPL 62 Query: 59 DEVTPAEFDALLLPGG-HSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGP-QLLISADVI 116 EV E+D ++LPGG + R V + F SG+ V AIC P +L+ D+ Sbjct: 63 VEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAAICAAPATVLVPHDIF 122 Query: 117 RGRKLTAVKPIIIDVKNAGAEFYDQEVVVD-KDQLVTSRTPDDLPAFNREALRLLGA 172 +T + K ++ D+ VV D + +L+TS+ P F + + LL Sbjct: 123 PIGNMTGFPTLKD--KIPAEQWLDKRVVWDARVKLLTSQGPGTAIDFGLKIIDLLVG 177 >1PDW-A nrPDB Length = 197 Score = 155 bits (392), Expect = 8e-39, Method: Composition-based stats. Identities = 47/174 (27%), Positives = 76/174 (43%), Gaps = 5/174 (2%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 SK+ V++ E+ E P D R+AG +V T+ AGK + + D S+++ Sbjct: 3 SKRALVILAKGAEEMETVIPVDVMRRAGIKV-TVAGLAGKDPVQCSRDVVICPDASLEDA 61 Query: 62 TP-AEFDALLLPGGH-SPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGR 119 +D ++LPGG+ L ++ N + AIC GP L++ ++ G Sbjct: 62 KKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALLAHEIGFGS 121 Query: 120 KLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLV-TSRTPDDLPAFNREALRLLGA 172 K+T P+ D G + E V+KD L+ TSR P F + L Sbjct: 122 KVTT-HPLAKDKMMNGGHYTYSENRVEKDGLILTSRGPGTSFEFALAIVEALNG 174 >3OT1-B nrPDB Length = 208 Score = 134 bits (336), Expect = 3e-32, Method: Composition-based stats. Identities = 44/174 (25%), Positives = 69/174 (39%), Gaps = 4/174 (2%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 MSK+I V + E+ E D +AG +V V+G +G +T +++++ Sbjct: 8 MSKRILVPVAHGSEEMETVIIVDTLVRAGFQVTMAAVGDKLQVQGSRG-VWLTAEQTLEA 66 Query: 61 VTPAEFDALLLPGGHSPDYLRGDNR-FVTFTRDFVNSGKPVFAICHGPQLLIS-ADVIRG 118 + FDAL LPGG D+ + F GK V AIC P L+ + G Sbjct: 67 CSAEAFDALALPGGVGGAQAFADSTALLALIDAFSQQGKLVAAICATPALVFAKQQKFVG 126 Query: 119 RKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 172 ++T P D + + L+TS+ P F + LL Sbjct: 127 ARMTC-HPNFFDHIPSERLSRQRVCYYATQHLLTSQGPGTALEFALAMIALLAG 179 >3MGK-A nrPDB Length = 211 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 37/179 (20%), Positives = 71/179 (39%), Gaps = 15/179 (8%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEF--RKAGHEVITIEKQAGKTVKGKKGEASVTI---D 55 +S +I VL+ ++FE + P + F + E+ I G +K ++ D Sbjct: 3 LSYRIDVLLFNKFETLDVFGPVEIFGNLQDDFELNFISSDGGLVESSQKVRVETSLYTRD 62 Query: 56 KSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADV 115 ++I+++ L +PGG D+ F+ F + V K + ++C G LL A + Sbjct: 63 ENIEKI-------LFVPGGSGTREKVNDDNFINFIGNMVKESKYIISVCTGSALLSKAGI 115 Query: 116 IRGRKLTAVKPIIIDVKNAGAE--FYDQEVVVDKDQLVTSRTPDDLPAFNREAL-RLLG 171 + G++ T K V + + + V + TS + L+G Sbjct: 116 LNGKRATTNKRSFKWVTEQNEDVLWVKEARWVKDGNIYTSSGVSAGIDMTLGFIEDLIG 174 >4K2H-A nrPDB Length = 188 Score = 89.8 bits (221), Expect = 6e-19, Method: Composition-based stats. Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 7/172 (4%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVT 62 KK+AVL+ FE++E D R+ +V T+ + V + + D ++ E Sbjct: 5 KKVAVLLAPGFEEAEAIVTLDILRRLHIDVETLACAESRAVVSYH-DIPMVADSTLSERQ 63 Query: 63 PAEFDALLLPGG-HSPDYLRGDNRFVTFTRDFVNSGKPVFAIC-HGPQLLISADVIRGRK 120 A FDA++LPGG L + + F +GK + I ++L + +++GR+ Sbjct: 64 QALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPIASAAARVLGAHGLLKGRR 123 Query: 121 LTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREA-LRLLG 171 + V + D VV+ L++ + + F RLLG Sbjct: 124 YVCSGDLWKAV--PEGVYVDA-PVVEDGNLISGKGLGHVFDFALTLSARLLG 172 >4GE0-A nrPDB Length = 194 Score = 80.1 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 35/173 (20%), Positives = 75/173 (43%), Gaps = 10/173 (5%) Query: 4 KIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKT-VKGKKGEASVTIDKSIDEVT 62 K+ + + D ++ EF++P F++A + ++ K + + + ++S E+ Sbjct: 6 KVCLFVADGTDEIEFSAPWGIFKRAEIPIDSVYVGENKDRLVKMSRDVEMYANRSYKEIP 65 Query: 63 PAE-----FDALLLPGG-HSPDYLRGDNRFVTFTRDFVNS-GKPVFAICHGPQLLISADV 115 A+ +D ++PGG L ++F K + IC GP L Sbjct: 66 SADDFAKQYDIAIIPGGGLGAKTLSTTPFVQQVVKEFYKKPNKWIGMICAGP-LTAKTSG 124 Query: 116 IRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALR 168 + +++T + ++ G ++ DQ VV+++ L+TS+ P F + L Sbjct: 125 LPNKQITGHPSVRGQLEEGGYKYLDQPVVLEE-NLITSQGPGTAMLFGLKLLE 176 >3F5D-A nrPDB Length = 206 Score = 54.7 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 38/173 (21%), Positives = 65/173 (37%), Gaps = 13/173 (7%) Query: 3 KKIAVLITDEFEDSEFTSPADEF-RKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 KK LI D++ D E A ++ V T+ + G ++D I + Sbjct: 4 KKALFLILDQYADWEGVYLASALNQREDWSVHTVSLD---PIVSSIGGFKTSVDYIIG-L 59 Query: 62 TPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKL 121 PA F+ L++ GG S + + + F + P+ AIC L ++ Sbjct: 60 EPANFNLLVMIGGDSWSN--DNKKLLHFVKTAFQKNIPIAAICGAVDFLAKNGLLNNHSH 117 Query: 122 TA-VKPIIIDVKN--AGAEFYDQEVVVDKDQLVTSRT--PDDLPAFNREALRL 169 T + D K + F +++ V DK LVT+ P + E + Sbjct: 118 TGNFVYLWKDYKQYKPISSFVEKQAVRDK-NLVTANGTAPIEFTNLILEMIDF 169 >4D1Y-A nrPDB Length = 200 Score = 48.9 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 65/178 (36%), Gaps = 12/178 (6%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 M+KK+AVL + + F + G K +K G + +D I Sbjct: 26 MAKKVAVLAVNPVNGCGLFQYLEAFFENGISYKVFAVSDTKEIKTNSGMV-LIVDDVIAN 84 Query: 61 VT--PAEFDALLLPGGHSPDYLRG------DNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 + EFDAL+ G + + + + + F GK + C G + Sbjct: 85 LKGHEDEFDALVFSCGDAVPVFQQYANQPYNVDLMEVIKTFGEKGKMMIGHCAGAMMFDF 144 Query: 113 ADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 + +G+K+ AV P+ G D++ +D T++ + + + + L Sbjct: 145 TGITKGKKV-AVHPLAKPAIQNGIA-TDEKSEID-GNFFTAQDENTIWTMLPKVIEAL 199 >3CNE-A nrPDB Length = 175 Score = 48.5 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 34/178 (19%), Positives = 65/178 (36%), Gaps = 12/178 (6%) Query: 1 MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDE 60 M+KK+AVL + + F + G K +K G + +D I Sbjct: 1 MAKKVAVLAVNPVNGCGLFQYLEAFFENGISYKVFAVSDTKEIKTNSGMV-LIVDDVIAN 59 Query: 61 VT--PAEFDALLLPGGHSPDYLRG------DNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 + EFDAL+ G + + + + + F GK + C G + Sbjct: 60 LKGHEDEFDALVFSCGDAVPVFQQYANQPYNVDLMEVIKTFGEKGKMMIGHCAGAMMFDF 119 Query: 113 ADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNREALRLL 170 + +G+K+ AV P+ G D++ +D T++ + + + + L Sbjct: 120 TGITKGKKV-AVHPLAKPAIQNGIA-TDEKSEID-GNFFTAQDENTIWTMLPKVIEAL 174 >1OY1-A nrPDB Length = 228 Score = 42.4 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 45/142 (31%), Gaps = 32/142 (22%) Query: 3 KKIAVLIT-----DEFEDSEFTSPADEFRKAGHEVITIEKQA----------GKTVKGKK 47 KKI V+++ D E E ++G + + G+ + + Sbjct: 5 KKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQQVDVINHLTGEAMTETR 64 Query: 48 ------GEASVTIDKSIDEVTPAEFDALLLPGGHS-----------PDYLRGDNRFVTFT 90 + + + + AE DAL++PGG D Sbjct: 65 NVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLSNFASLGSECTVDRELKALA 124 Query: 91 RDFVNSGKPVFAICHGPQLLIS 112 + +GKP+ +C P +L Sbjct: 125 QAMHQAGKPLGFMCIAPAMLPK 146 >4LRU-A nrPDB Length = 239 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 32/193 (16%), Positives = 58/193 (30%), Gaps = 52/193 (26%) Query: 16 SEFTSPADEFRKAGHEVITIEKQA--------------------GKTVKGKKGEASVTID 55 E P + FRK G+E+ + + ++ Sbjct: 30 VEALHPFEVFRKKGYEIQLASETGTFGWDDHSVVPDFLNGEDKEIFDNVNSEFNVALKNL 89 Query: 56 KSIDEVTPAEFDALLLPGGHSPDYLRGDNR-FVTFTRDFVNSGKPVFAICHGPQLL---- 110 K ++ P ++D GH + + + + G V A+CHGP + Sbjct: 90 KKASDLDPNDYDIFFGSAGHGTLFDYPNAKDLQKIATTVYDKGGVVSAVCHGPAIFENLN 149 Query: 111 ---ISADVIRGRKLTAVKPIIIDVK-------------------NAGAEFYDQEVVVD-- 146 +I+G+K+T I D+ GA + + E D Sbjct: 150 DPKTGEPLIKGKKITGFTDIGEDILGVTDIMKKGNLLTIKQVAEKEGATYIEPEGPWDNF 209 Query: 147 ---KDQLVTSRTP 156 ++VT P Sbjct: 210 TVTDGRIVTGVNP 222 >1K9V-F nrPDB Length = 201 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 9/77 (11%) Query: 55 DKSIDEVTP---AEFDALLLPG----GHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGP 107 D SI+ V +D L +PG G LR ++ + F R V + V +C G Sbjct: 29 DVSIELVESPRNDLYDLLFIPGVGHFGEGMRRLREND-LIDFVRKHVEDERYVVGVCLGM 87 Query: 108 QLLI-SADVIRGRKLTA 123 QLL ++ G K + Sbjct: 88 QLLFEESEEAPGVKGLS 104 >5JZM-A nrPDB Length = 288 Score = 40.5 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 23/139 (16%), Positives = 42/139 (30%), Gaps = 25/139 (17%) Query: 12 EFEDSEFTSPADEFRKAGHEVITIEKQAG-------------KTVKG--KKGEASVTIDK 56 E P KAG + V G K ++S Sbjct: 76 GNHPVETLLPMYHLDKAGFSFDIATLSGNPVKFEWWAMPREDQEVNGLYSKYQSSFRQPL 135 Query: 57 SIDEV------TPAEFDALLLPGGHSP-DYLRGDNRFVTFTRDFVNSGKPVFAICHGPQL 109 + +V +++ + +PGGH L + + K + ++CHGP Sbjct: 136 KLSDVIETALGEDSDYIGVFIPGGHGALMGLPDSQEVKAVLQWAMKQNKFIISLCHGPAA 195 Query: 110 LISAD---VIRGRKLTAVK 125 ++ + G K+ A Sbjct: 196 FLAVGDDPLFAGYKIVAFP 214 >2NV0-A nrPDB Length = 196 Score = 39.3 bits (90), Expect = 9e-04, Method: Composition-based stats. Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%) Query: 65 EFDALLLPGGHSP--DYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 E D L+LPGG S L +F+ R+F GKP+F C G +L Sbjct: 38 EVDGLILPGGESTTMRRLIDTYQFMEPLREFAAQGKPMFGTCAGLIILAK 87 >3KKL-A nrPDB Length = 244 Score = 38.9 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 54/162 (33%), Gaps = 29/162 (17%) Query: 16 SEFTSPADEFRKAGHEVITIEKQAGK--------------------TVKGKKGEASVTID 55 E D F K G EV + + G K ++ Sbjct: 29 VEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARI 88 Query: 56 KSIDEVTPAEFDALLLPGGHSP--DYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISA 113 K+ +EV +++ GH DY + +G + AICHGP L+ Sbjct: 89 KTANEVNASDYKVFFASAGHGALFDYPKA-KNLQDIASKIYANGGVIAAICHGP--LLFD 145 Query: 114 DVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRT 155 +I + +P+I G + E+ + D ++ SR Sbjct: 146 GLIDIK---TTRPLIEGKAITGFP-LEGEIALGVDDILRSRK 183 >5XR3-A nrPDB Length = 300 Score = 37.8 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 24/172 (13%), Positives = 53/172 (30%), Gaps = 28/172 (16%) Query: 12 EFEDSEFTSPADEFRKAGHEVITIEKQAGKT--------------------VKGKKGEAS 51 E P +AG +V +K K + Sbjct: 76 GNHPVEMLLPLHHLMEAGFDVDVATLSGYPVKLELWAMPTEDEAVISTYNKLKEKLKQPK 135 Query: 52 VTIDKSIDEVTPA-EFDALLLPGGHSPDY-LRGDNRFVTFTRDFVNSGKPVFAICHGPQL 109 D +E+ P ++ ++ +PGGH+ + +++ + + + HGP Sbjct: 136 KLADVIKNELGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALDNDRFIVTLXHGPAA 195 Query: 110 LISADV------IRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRT 155 L+SA + + G + + + N + + L+T + Sbjct: 196 LLSAGLNREKSPLEGYSVCVFPDSLDEGANIEIGYLPGRLKWLVADLLTKQG 247 >1Q7R-A nrPDB Length = 219 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%) Query: 67 DALLLPGGHSP--DYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 D L+LPGG S L + + F +GKP+F C G LL Sbjct: 62 DGLVLPGGESTTMRRLIDRYGLMEPLKQFAAAGKPMFGTCAGLILLAK 109 >4WXY-B nrPDB Length = 228 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%) Query: 67 DALLLPGGHSP--DYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 D L+LPGG S L + + F +GKP+F C G LL Sbjct: 71 DGLVLPGGESTTMRRLIDRYGLMEPLKQFAAAGKPMFGTCAGLILLAK 118 >3D54-D nrPDB Length = 213 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 6/61 (9%) Query: 64 AEFDALLLPGGHS-PDYLR-----GDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIR 117 +++ ++LPGG S DYLR + GK + IC+G Q+LI +++ Sbjct: 40 DDYELIILPGGFSYGDYLRPGAVAAREKIAFEIAKAAERGKLIMGICNGFQILIEMGLLK 99 Query: 118 G 118 G Sbjct: 100 G 100 >1QVW-A nrPDB Length = 237 Score = 37.4 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 45/130 (34%), Gaps = 27/130 (20%) Query: 6 AVLITDEFED----SEFTSPADEFRKAGHEVITIEKQA---------------GKTVKGK 46 V +D + E P + FRK G EV + + G+ Sbjct: 15 DVFYSDGMKTGVFVVEALHPFNTFRKEGFEVDFVSETGKFGWDEHSLAKDFLNGQDETDF 74 Query: 47 KGEAS-----VTIDKSIDEVTPAEFDALLLPGGHSP--DYLRGDNRFVTFTRDFVNSGKP 99 K + S + K+ EV ++ + GH DY + + + +G Sbjct: 75 KNKDSDFNKTLAKIKTPKEVNADDYQIFMASAGHGTLFDYPKAKD-LQDIASEIYANGGV 133 Query: 100 VFAICHGPQL 109 V A+CHGP + Sbjct: 134 VAAVCHGPAM 143 >1N57-A nrPDB Length = 291 Score = 37.0 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 37/144 (25%), Gaps = 35/144 (24%) Query: 4 KIAVLITD--------------EFEDSEFTSPADEFRKAGHEVITIEKQAGKT------- 42 KI V+ D E P AG E T Sbjct: 50 KILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAM 109 Query: 43 -------------VKGKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDY-LRGDNRFVT 88 K D +E+ A+ +PGGH L Sbjct: 110 PHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAA 169 Query: 89 FTRDFVNSGKPVFAICHGPQLLIS 112 + + + + V ++CHGP ++ Sbjct: 170 ALQWAIKNDRFVISLCHGPAAFLA 193 >1SY7-A nrPDB Length = 715 Score = 36.6 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 42/113 (37%), Gaps = 3/113 (2%) Query: 2 SKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEV 61 S+++A++I D +++ + + + I + K ++ Sbjct: 534 SRRVAIIIADGYDNVAYDAAYAAISANQAIPLVIGPRRSKVTAANGSTVQ--PHHHLEGF 591 Query: 62 TPAEFDALLLPGG-HSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISA 113 DA+ +PGG + + L + R + + R+ K + A L+ A Sbjct: 592 RSTMVDAIFIPGGAKAAETLSKNGRALHWIREAFGHLKAIGATGEAVDLVAKA 644 >1OX5-A nrPDB Length = 555 Score = 35.8 bits (81), Expect = 0.009, Method: Composition-based stats. Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 7/90 (7%) Query: 32 VITIEKQAGKTVKG--KKGEASVTIDKSIDEVTPAEFDALLLPG----GHSPDYLRGDNR 85 VI +E +++ + V + KS + + L+LPG GH D L + Sbjct: 9 VIDVESGNLQSLTNAIEHLGYEVQLVKSPKDFNISGTSRLILPGVGNYGHFVDNLF-NRG 67 Query: 86 FVTFTRDFVNSGKPVFAICHGPQLLISADV 115 F R+++ SGKP+ IC G Q L + V Sbjct: 68 FEKPIREYIESGKPIMGICVGLQALFAGSV 97 >1KA9-H nrPDB Length = 200 Score = 34.7 bits (78), Expect = 0.020, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 4/76 (5%) Query: 64 AEFDALLLPG-GHSPDYLRG--DNRFVTFTRDFVNSGKPVFAICHGPQLLIS-ADVIRGR 119 E D L+LPG GH +R ++ FV R + G P IC G Q+L ++ G Sbjct: 39 EEADLLVLPGQGHFGQVMRAFQESGFVERVRRHLERGLPFLGICVGMQVLYEGSEEAPGV 98 Query: 120 KLTAVKPIIIDVKNAG 135 + + P + AG Sbjct: 99 RGLGLVPGEVRRFRAG 114 >1F4U-A nrPDB Length = 368 Score = 32.4 bits (72), Expect = 0.098, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 49/137 (35%), Gaps = 16/137 (11%) Query: 50 ASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTR-----DFVNSGKPVFAIC 104 S ++ ++ ++ + LLL G+ N + FTR + AI Sbjct: 186 VSRVVNSNLSDIEKLGYIILLLIAGNETTTNLISNSVIDFTRFNLWQRIREENLYLKAI- 244 Query: 105 HGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFY---------DQEVVVDKDQLVTSRT 155 L S V+R + T + + D E+ D+EV D ++ + R Sbjct: 245 -EEALRYSPPVMRTVRKTKERVKLGDQTIEEGEYVRVWIASANRDEEVFHDGEKFIPDRN 303 Query: 156 PDDLPAFNREALRLLGA 172 P+ +F LGA Sbjct: 304 PNPHLSFGSGIHLCLGA 320 >4GUD-A nrPDB Length = 211 Score = 32.4 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 30/97 (30%), Gaps = 12/97 (12%) Query: 67 DALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKP 126 D L LPG + + KP+ IC G QLL KL+ K Sbjct: 42 DKLFLPGVGTASEAMKNLTERDLIELVKRVEKPLLGICLGMQLL--------GKLSEEKG 93 Query: 127 IIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFN 163 D D EV + L T P +N Sbjct: 94 QKADEIVQCLGLVDGEVRL----LQTGDLPLPHMGWN 126 >3R75-A nrPDB Length = 645 Score = 32.0 bits (71), Expect = 0.13, Method: Composition-based stats. Identities = 27/115 (23%), Positives = 45/115 (39%), Gaps = 17/115 (14%) Query: 59 DEVTPAEFDALLLPGGHSPDYLRGD---NRFVTFTRDFVNSGKPVFAICHGPQLLISA-D 114 D V A +D +++ G GD R + R ++ GKP A+C Q+L + Sbjct: 480 DAVDLARYDVVVMGPGPGDPSDAGDPRIARLYAWLRHLIDEGKPFMAVCLSHQILNAILG 539 Query: 115 VIRGRKLTAVKPIIIDVKNAG------------AEFYDQEVVVDKDQLVT-SRTP 156 + R+ + I +++ G A+ E+ VD V SR P Sbjct: 540 IPLVRREVPNQGIQVEIDLFGQRERVGFYNTYVAQTVRDEMDVDGVGTVAISRDP 594 >2ISS-D nrPDB Length = 208 Score = 32.0 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 10/52 (19%) Query: 67 DALLLPGGHSPDYLR------GDNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 D L+LPGG S +R D + V N+G PVFA C G LL Sbjct: 59 DGLILPGGESTTMIRILKEMDMDEKLVERI----NNGLPVFATCAGVILLAK 106 >4BIM-A nrPDB Length = 746 Score = 30.8 bits (68), Expect = 0.29, Method: Composition-based stats. Identities = 17/103 (16%), Positives = 34/103 (33%), Gaps = 23/103 (22%) Query: 23 DEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRG 82 ++ K G +V I + + +D++ FDA+++ + + Sbjct: 617 EQLEKDGLKVTVIAE-----------YLASGVDQTYSAADATAFDAVVV--AEGAERVFS 663 Query: 83 DNRFVT----------FTRDFVNSGKPVFAICHGPQLLISADV 115 ++ D GKPV A+ + L S V Sbjct: 664 GKGAMSPLFPAGRPSQILTDGYRWGKPVAAVGSAKKALQSIGV 706 >4NFY-A nrPDB Length = 307 Score = 30.4 bits (67), Expect = 0.37, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 36/99 (36%), Gaps = 6/99 (6%) Query: 3 KKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVT 62 KI V+ F ++ + KAGHEV+ IEK K K+ D V Sbjct: 1 MKIVVITEKPFAENAVKGIREILEKAGHEVVMIEK-----YKKKEDVIERIKDADGVIVR 55 Query: 63 PAEFDALLLPGGHSPD-YLRGDNRFVTFTRDFVNSGKPV 100 + D ++ G +R + + N GK V Sbjct: 56 SDKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIV 94 >1UE8-A nrPDB Length = 367 Score = 30.4 bits (67), Expect = 0.39, Method: Composition-based stats. Identities = 37/157 (23%), Positives = 60/157 (38%), Gaps = 17/157 (10%) Query: 31 EVITIEKQAGKTVKGKKGEASV--TIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVT 88 E+I+ K+ + KGK+ + ++ E+ + LL+ G+ N Sbjct: 166 ELISFSKKELDSRKGKEIVDLTGKIANSNLSELEKEGYFILLMIAGNETTTNLIGNAIED 225 Query: 89 FTR----DFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAE----FY- 139 FT D+V + A+ L S V+R ++T K I D E + Sbjct: 226 FTLYNSWDYVREKGALKAV--EEALRFSPPVMRTIRVTKEKVKIRDQVIDEGELVRVWIA 283 Query: 140 ----DQEVVVDKDQLVTSRTPDDLPAFNREALRLLGA 172 D+EV D D + RTP+ +F LGA Sbjct: 284 SANRDEEVFKDPDSFIPDRTPNPHLSFGSGIHLCLGA 320 >3FIJ-A nrPDB Length = 254 Score = 30.1 bits (66), Expect = 0.53, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 19/28 (67%) Query: 83 DNRFVTFTRDFVNSGKPVFAICHGPQLL 110 D+ + R +++GKP+FAIC G QL+ Sbjct: 94 DSYEIALVRAALDAGKPIFAICRGMQLV 121 >4WEA-A nrPDB Length = 515 Score = 29.7 bits (65), Expect = 0.71, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 38/95 (40%), Gaps = 6/95 (6%) Query: 70 LLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIII 129 +P G + D VT + V + + IC P ++ G T + ++ Sbjct: 24 AVPNGTIVKTITNDQIEVTNATELVQNSS-IGEICDSP-----HQILDGENCTLIDALLG 77 Query: 130 DVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNR 164 D + G + ++ V++ + ++ P D+P + Sbjct: 78 DPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYAS 112 >6BKP-A nrPDB Length = 323 Score = 28.9 bits (63), Expect = 1.0, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 38/95 (40%), Gaps = 6/95 (6%) Query: 70 LLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIII 129 +P G + D VT + V + + IC P ++ G T + ++ Sbjct: 13 AVPNGTIVKTITNDRIEVTNATELVQNSS-IGEICDSP-----HQILDGENCTLIDALLG 66 Query: 130 DVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNR 164 D + G + ++ V++ + ++ P D+P + Sbjct: 67 DPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYAS 101 >6BKN-A nrPDB Length = 323 Score = 28.9 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 37/95 (38%), Gaps = 6/95 (6%) Query: 70 LLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIII 129 +P G + D VT + V S IC P ++ G T + ++ Sbjct: 13 AVPNGTIVKTITNDQIEVTNATELVQSSS-TGGICDSP-----HQILDGENCTLIDALLG 66 Query: 130 DVKNAGAEFYDQEVVVDKDQLVTSRTPDDLPAFNR 164 D + G + ++ V++ + ++ P D+P + Sbjct: 67 DPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYAS 101 >2YWB-A nrPDB Length = 503 Score = 28.9 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 3/58 (5%) Query: 55 DKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLIS 112 D ++EV AL+L GG P + + R +SG P+ IC+G QLL Sbjct: 32 DAPLEEVLKHRPQALILSGG--PRSVFDPDAPRPDPR-LFSSGLPLLGICYGMQLLAQ 86 >6FQB-E nrPDB Length = 260 Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 28/77 (36%), Gaps = 4/77 (5%) Query: 49 EASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRF---VTFTRDFVNSGKPVFAICH 105 +V I D+ +D GG + + +++ + V AIC Sbjct: 49 HVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGVVLAICG 108 Query: 106 GPQLLISADV-IRGRKL 121 G QLL V G+++ Sbjct: 109 GFQLLGQYYVEASGKRI 125 >3G7Q-A nrPDB Length = 417 Score = 28.1 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 16/43 (37%), Positives = 22/43 (51%), Gaps = 2/43 (4%) Query: 68 ALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFAICH--GPQ 108 A++L GG+ + F T D V SGK A+C+ GPQ Sbjct: 33 AIMLGGGNPAHIPAMQDYFQTLLTDMVESGKAADALCNYDGPQ 75 >4Z6K-A nrPDB Length = 346 Score = 27.7 bits (60), Expect = 2.6, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 23/53 (43%), Gaps = 6/53 (11%) Query: 74 GHSPDYLRGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKP 126 G +Y+ + +V + V+S + +C G V +G K+T KP Sbjct: 118 GSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVT------VYKGLKMTDTKP 164 >4M4V-A nrPDB Length = 422 Score = 27.4 bits (59), Expect = 3.2, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 14/35 (40%) Query: 117 RGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLV 151 G + +P+ V + + + VVD D + Sbjct: 117 NGASPSDWEPLREVVGSGAGTWGNPTPVVDDDNTI 151 >5EM0-A nrPDB Length = 135 Score = 27.4 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Query: 11 DEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALL 70 EF ++ +P F G + + I+ +AG ++GKKG + I K+ + +D + Sbjct: 56 KEFNEAGQLAPTGLFL-GGAKYMVIQGEAGAVIRGKKGAGGICIKKTGQAMVFGIYDEPV 114 Query: 71 LPG 73 PG Sbjct: 115 APG 117 >4BI9-A nrPDB Length = 454 Score = 27.4 bits (59), Expect = 3.8, Method: Composition-based stats. Identities = 18/112 (16%), Positives = 36/112 (32%), Gaps = 10/112 (8%) Query: 15 DSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPGG 74 S S F GH + K + + K + +K+++E+ + L G Sbjct: 21 TSSTFSAKRVFVVGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEELLAESINGALQNTG 80 Query: 75 HSPDYLRGDNRFV--TFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAV 124 ++ V F + +S + GP + + G +A Sbjct: 81 LHDGRAALVDKLVVGNFLGELFSSQGHL-----GPAAV---GSLSGSNSSAF 124 >5NZC-A nrPDB Length = 132 Score = 27.0 bits (58), Expect = 4.9, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 25/46 (54%) Query: 28 AGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPG 73 G + + I+ +AG ++GKKG +TI K+ + ++ + PG Sbjct: 69 GGIKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPG 114 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.132 0.319 Lambda K H 0.267 0.0407 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,733,095 Number of Sequences: 36641 Number of extensions: 202415 Number of successful extensions: 764 Number of sequences better than 10.0: 50 Number of HSP's better than 10.0 without gapping: 54 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 659 Number of HSP's gapped (non-prelim): 104 length of query: 172 length of database: 10,336,785 effective HSP length: 90 effective length of query: 82 effective length of database: 7,039,095 effective search space: 577205790 effective search space used: 577205790 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 55 (25.8 bits)