BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P43588 (306 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5MPD-V nrPDB 635 0.0 4O8Y-B nrPDB 499 e-142 5L4K-V nrPDB 414 e-116 4D10-E nrPDB 130 5e-31 4F7O-A nrPDB 130 8e-31 6FJU-A nrPDB 87 7e-18 6FEC-5 nrPDB 63 2e-10 3J8B-H nrPDB 63 2e-10 5CW6-A nrPDB 62 4e-10 5CW3-A nrPDB 46 3e-05 5VFQ-Z nrPDB 42 3e-04 3JCO-U nrPDB 42 3e-04 6MSD-Z nrPDB 42 4e-04 6FVW-U nrPDB 41 5e-04 3J8B-F nrPDB 38 0.005 5A5T-F nrPDB 38 0.006 6B6X-A nrPDB 31 0.76 3BC1-A nrPDB 30 1.0 1H65-A nrPDB 29 2.5 5A29-A nrPDB 28 5.6 2D5W-A nrPDB 28 6.7 3J98-H nrPDB 27 8.5 3NVS-A nrPDB 27 9.1 >5MPD-V nrPDB Length = 306 Score = 635 bits (1638), Expect = 0.0, Method: Compositional matrix adjust. Identities = 306/306 (100%), Positives = 306/306 (100%) Query: 1 MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD 60 MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD Sbjct: 1 MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD 60 Query: 61 YTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSS 120 YTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSS Sbjct: 61 YTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSS 120 Query: 121 VDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLL 180 VDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLL Sbjct: 121 VDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLL 180 Query: 181 NKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAA 240 NKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAA Sbjct: 181 NKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAA 240 Query: 241 TKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGV 300 TKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGV Sbjct: 241 TKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGV 300 Query: 301 NSVAIK 306 NSVAIK Sbjct: 301 NSVAIK 306 >4O8Y-B nrPDB Length = 240 Score = 499 bits (1286), Expect = e-142, Method: Compositional matrix adjust. Identities = 238/238 (100%), Positives = 238/238 (100%) Query: 2 ERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDY 61 ERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDY Sbjct: 3 ERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDY 62 Query: 62 TVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSV 121 TVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSV Sbjct: 63 TVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSV 122 Query: 122 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLN 181 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLN Sbjct: 123 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLN 182 Query: 182 KANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLA 239 KANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLA Sbjct: 183 KANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLA 240 >5L4K-V nrPDB Length = 310 Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust. Identities = 196/290 (67%), Positives = 231/290 (79%) Query: 17 DTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT 76 D DT E VYISS+ALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGT Sbjct: 21 DAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGT 80 Query: 77 GVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRA 136 GVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWLS VD+NTQ+SFE L+ RA Sbjct: 81 GVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERA 140 Query: 137 VAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHY 196 VAVVVDPIQSVKGKVVIDAFRLI+ ++ EPRQTTSN G LNK +IQALIHGLNRHY Sbjct: 141 VAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHY 200 Query: 197 YSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIE 256 YS+ I+Y K E KML+NLHK+ W GL + DY E + N + K M+++A+ Y+K +E Sbjct: 201 YSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVE 260 Query: 257 EEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK 306 EE ++T E+L + VG+QDPK+HL E D + +NIV L A +++V K Sbjct: 261 EEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310 >4D10-E nrPDB Length = 334 Score = 130 bits (328), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 81/197 (41%), Positives = 119/197 (60%), Gaps = 11/197 (5%) Query: 29 ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT--GVSVEAVDDV 86 IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V+ +A Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 Query: 87 FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 146 + A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP ++ Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 Query: 147 VK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQAL-IHGLNRHYYSLNIDYH 204 + GKV + AFR G + P + T LNK I+ +H + YY+L + Y Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNK--IEDFGVHC--KQYYALEVSYF 229 Query: 205 KTAKETKMLMNLHKEQW 221 K++ + K+L L + W Sbjct: 230 KSSLDRKLLELLWNKYW 246 >4F7O-A nrPDB Length = 257 Score = 130 bits (327), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 81/197 (41%), Positives = 119/197 (60%), Gaps = 11/197 (5%) Query: 29 ISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT--GVSVEAVDDV 86 IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V+ +A Sbjct: 57 ISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAYE 115 Query: 87 FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 146 + A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP ++ Sbjct: 116 YMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRT 175 Query: 147 VK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQAL-IHGLNRHYYSLNIDYH 204 + GKV + AFR G + P + T LNK I+ +H + YY+L + Y Sbjct: 176 ISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNK--IEDFGVH--CKQYYALEVSYF 229 Query: 205 KTAKETKMLMNLHKEQW 221 K++ + K+L L + W Sbjct: 230 KSSLDRKLLELLWNKYW 246 >6FJU-A nrPDB Length = 228 Score = 87.4 bits (215), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 45/124 (36%), Positives = 76/124 (61%), Gaps = 2/124 (1%) Query: 27 VYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDV 86 V I +AL K++KH + + EV GL++G+ + + D Q GT V+ +D++ Sbjct: 29 VRIYPLALAKVVKHAASSLQREVAGLLVGKSAGK-VLEIWDAVTGEQYGTPAYVQ-LDEM 86 Query: 87 FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQS 146 AK+ + L ++ ++ +VGWYHSHPG +LS D++TQK ++ + S+AVA+VVDP+ Sbjct: 87 VMAKVAEELSKSDKNLYIVGWYHSHPGLDVFLSPTDIDTQKRYQAMFSKAVALVVDPVDY 146 Query: 147 VKGK 150 K + Sbjct: 147 AKTR 150 >6FEC-5 nrPDB Length = 352 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 48/168 (28%), Positives = 89/168 (52%), Gaps = 11/168 (6%) Query: 21 DDTKETVYISSIALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVNVVDVFAMPQSGTGV 78 D + V I + +LK++KH + G EV+ G++LG V+D + + + F PQ Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQHTEDD 91 Query: 79 SVEAVDDV-FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAV 137 + D+V +Q +MM L+ D + VGWY S +G +++ +++Q S++ +V Sbjct: 92 A--DFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESV 148 Query: 138 AVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANI 185 ++ DPI++ +G + + A+RL T L+ + + + L KANI Sbjct: 149 VLIYDPIKTAQGSLSLKAYRL--TPKLMEVCKEKDFSPEA--LKKANI 192 >3J8B-H nrPDB Length = 343 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 48/168 (28%), Positives = 89/168 (52%), Gaps = 11/168 (6%) Query: 21 DDTKETVYISSIALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVNVVDVFAMPQSGTGV 78 D + V I + +LK++KH + G EV+ G++LG V+D + + + F PQ Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED-RLEITNCFPFPQHTEDD 91 Query: 79 SVEAVDDV-FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAV 137 + D+V +Q +MM L+ D + VGWY S +G +++ +++Q S++ +V Sbjct: 92 A--DFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESV 148 Query: 138 AVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANI 185 ++ DPI++ +G + + A+RL T L+ + + + L KANI Sbjct: 149 VLIYDPIKTAQGSLSLKAYRL--TPKLMEVCKEKDFSPEA--LKKANI 192 >5CW6-A nrPDB Length = 262 Score = 61.6 bits (148), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 26/148 (17%) Query: 27 VYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAM-------------PQ 73 V++ S A L + H + EVMGL +GE + V++ V + P+ Sbjct: 8 VHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVEISPE 67 Query: 74 SGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLN 133 + S EA ++ +M TGR VVGWYHSHP W S VDV TQ ++ ++ Sbjct: 68 QLSAASTEA------ERLAEM---TGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMD 118 Query: 134 SRAVAVV----VDPIQSVKGKVVIDAFR 157 V ++ ++ + G+V+ F+ Sbjct: 119 QGFVGLIFSCFIEDKNTKTGRVLYTCFQ 146 >5CW3-A nrPDB Length = 255 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 3/123 (2%) Query: 21 DDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYT--VNVVDVFAMPQSGTGV 78 D + + V + + + L+H + EVMGL++G F V+ + + + V Sbjct: 5 DSSLQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRV 64 Query: 79 SVEAVDDVFQAKMMDMLK-QTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAV 137 + + + A + L + R V+GWYHSHP S VDV TQ +++ ++ V Sbjct: 65 EISSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFV 124 Query: 138 AVV 140 ++ Sbjct: 125 GLI 127 >5VFQ-Z nrPDB Length = 286 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 59/124 (47%), Gaps = 11/124 (8%) Query: 25 ETVYISSIALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMP--QSGTGV 78 + V + + LL ++ H G+ G V+G++LG + ++V + FA+P + Sbjct: 3 QKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSW-QKKVLDVSNSFAVPFDEDDKDD 61 Query: 79 SVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVA 138 SV +D + M M K+ + +VGWYH+ P L D+ + ++ +V Sbjct: 62 SVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVL 117 Query: 139 VVVD 142 V++D Sbjct: 118 VIID 121 >3JCO-U nrPDB Length = 338 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 6/93 (6%) Query: 25 ETVYISSIALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVNVVDVFAMP--QSGTGVS 79 E V I+ + LL L H E +G++LG+ + T+ V + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 80 VEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHP 112 V +D + M +M K+ + ++GWYHS P Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGP 97 >6MSD-Z nrPDB Length = 324 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 31/124 (25%), Positives = 59/124 (47%), Gaps = 11/124 (8%) Query: 25 ETVYISSIALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMP--QSGTGV 78 + V + + LL ++ H G+ G V+G++LG + ++V + FA+P + Sbjct: 7 QKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSW-QKKVLDVSNSFAVPFDEDDKDD 65 Query: 79 SVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVA 138 SV +D + M M K+ + +VGWYH+ P L D+ + ++ +V Sbjct: 66 SVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNSVL 121 Query: 139 VVVD 142 V++D Sbjct: 122 VIID 125 >6FVW-U nrPDB Length = 304 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 45/93 (48%), Gaps = 6/93 (6%) Query: 25 ETVYISSIALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVNVVDVFAMP--QSGTGVS 79 E V I+ + LL L H E +G++LG+ + T+ V + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 80 VEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHP 112 V +D + M +M K+ + ++GWYHS P Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGP 97 >3J8B-F nrPDB Length = 327 Score = 38.1 bits (87), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 2/60 (3%) Query: 49 VMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWY 108 V+G +LG VD ++V V + F++P + + V AVD F M ++ K+ +++++GWY Sbjct: 116 VIGTLLGT-VDKHSVEVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGWY 173 >5A5T-F nrPDB Length = 364 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 2/60 (3%) Query: 49 VMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWY 108 V+G +LG VD ++V V + F++P + + V AVD F M ++ K+ +++++GWY Sbjct: 123 VIGTLLGT-VDKHSVEVTNCFSVPHNESEDEV-AVDMEFAKNMYELHKKVSPNELILGWY 180 >6B6X-A nrPDB Length = 637 Score = 30.8 bits (68), Expect = 0.76, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 17/30 (56%) Query: 164 LINNLEPRQTTSNTGLLNKANIQALIHGLN 193 L PRQ+T N G+L K + L+HG N Sbjct: 246 LFGTPRPRQSTVNLGVLRKDAVNILVHGHN 275 >3BC1-A nrPDB Length = 195 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 39/81 (48%), Gaps = 10/81 (12%) Query: 191 GLNRHYYSLNIDYHKTAKETKMLMNLHKEQ-------WQSGLKMYDYEEKEESNLAATKS 243 GL R + SL + + A +L +L EQ W S L+M+ Y E + L KS Sbjct: 79 GLER-FRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYSENPDIVLCGNKS 137 Query: 244 MVKIAEQYSKRIEEEKELTEE 264 + +Q + + EE +EL E+ Sbjct: 138 --DLEDQRAVKEEEARELAEK 156 >1H65-A nrPDB Length = 270 Score = 29.3 bits (64), Expect = 2.5, Method: Compositional matrix adjust. Identities = 19/96 (19%), Positives = 41/96 (42%), Gaps = 11/96 (11%) Query: 37 MLKHGRAGVPMEVM---GLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMD 93 M+ RAG + ++ GL+ G +++D +N++ F + ++ +D + +D Sbjct: 79 MVSRSRAGFTLNIIDTPGLIEGGYINDMALNIIKSFLLDKT--------IDVLLYVDRLD 130 Query: 94 MLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSF 129 + D++V G G W ++ T F Sbjct: 131 AYRVDNLDKLVAKAITDSFGKGIWNKAIVALTHAQF 166 >5A29-A nrPDB Length = 570 Score = 28.1 bits (61), Expect = 5.6, Method: Compositional matrix adjust. Identities = 13/39 (33%), Positives = 18/39 (46%), Gaps = 4/39 (10%) Query: 189 IHGLNRHY----YSLNIDYHKTAKETKMLMNLHKEQWQS 223 +H L HY + ++D H T + K H E WQS Sbjct: 152 VHELKNHYPYYPFLYHVDPHATERYIKAFWQAHVEDWQS 190 >2D5W-A nrPDB Length = 603 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 165 INNLEPRQTTSNTGLLNKANIQALIHGLNRH 195 IN E Q + GL +K QA++H LNR Sbjct: 308 INKFENCQVVKDLGLNDKRTRQAILHALNRE 338 >3J98-H nrPDB Length = 297 Score = 27.3 bits (59), Expect = 8.5, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 6/34 (17%) Query: 229 DYEEKEESNLAATKSMVKIA------EQYSKRIE 256 DY + EESN +A K ++K+A EQY K I+ Sbjct: 152 DYYKGEESNSSANKCLLKVAGYAAQLEQYQKAID 185 >3NVS-A nrPDB Length = 450 Score = 27.3 bits (59), Expect = 9.1, Method: Compositional matrix adjust. Identities = 23/92 (25%), Positives = 48/92 (52%), Gaps = 5/92 (5%) Query: 119 SSVDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTG 178 S VD+ T+ + Q N+ ++ + PI+ + G+V + + + AL+ TT T Sbjct: 9 SGVDLGTENLYFQSNAME-SLTLQPIELISGEVNLPGSKSVSNRALLLAALASGTTRLTN 67 Query: 179 LLNKANIQALIHGLNRHYYSLNIDYHKTAKET 210 LL+ +I+ +++ L + L ++Y +A +T Sbjct: 68 LLDSDDIRHMLNALTK----LGVNYRLSADKT 95 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5MPD-V nrPDB 449 e-127 5L4K-V nrPDB 433 e-122 4O8Y-B nrPDB 353 5e-98 4F7O-A nrPDB 220 5e-58 4D10-E nrPDB 220 8e-58 3J8B-H nrPDB 155 2e-38 6FEC-5 nrPDB 154 4e-38 5CW6-A nrPDB 147 5e-36 6FJU-A nrPDB 147 5e-36 5CW3-A nrPDB 144 5e-35 6MSD-Z nrPDB 128 2e-30 5VFQ-Z nrPDB 128 3e-30 6FVW-U nrPDB 112 3e-25 3JCO-U nrPDB 110 6e-25 Sequences not found previously or not previously below threshold: 3J8B-F nrPDB 69 3e-12 5A5T-F nrPDB 68 5e-12 4KIT-C nrPDB 37 0.013 2P87-A nrPDB 34 0.11 4DVY-P nrPDB 32 0.28 4DVZ-A nrPDB 32 0.41 3JAX-A nrPDB 30 1.5 4RM9-A nrPDB 30 1.7 6HIX-AK nrPDB 29 2.2 6ID1-L nrPDB 29 2.4 6DGB-A nrPDB 29 2.8 4MCR-A nrPDB 27 7.7 1MQS-A nrPDB 27 7.9 >5MPD-V nrPDB Length = 306 Score = 449 bits (1155), Expect = e-127, Method: Composition-based stats. Identities = 306/306 (100%), Positives = 306/306 (100%) Query: 1 MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD 60 MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD Sbjct: 1 MERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD 60 Query: 61 YTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSS 120 YTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSS Sbjct: 61 YTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSS 120 Query: 121 VDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLL 180 VDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLL Sbjct: 121 VDVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLL 180 Query: 181 NKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAA 240 NKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAA Sbjct: 181 NKANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAA 240 Query: 241 TKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGV 300 TKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGV Sbjct: 241 TKSMVKIAEQYSKRIEEEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGV 300 Query: 301 NSVAIK 306 NSVAIK Sbjct: 301 NSVAIK 306 >5L4K-V nrPDB Length = 310 Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats. Identities = 196/290 (67%), Positives = 231/290 (79%) Query: 17 DTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT 76 D DT E VYISS+ALLKMLKHGRAGVPMEVMGLMLGEFVDDYTV V+DVFAMPQSGT Sbjct: 21 DAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGT 80 Query: 77 GVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRA 136 GVSVEAVD VFQAKM+DMLKQTGR +MVVGWYHSHPGFGCWLS VD+NTQ+SFE L+ RA Sbjct: 81 GVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERA 140 Query: 137 VAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQALIHGLNRHY 196 VAVVVDPIQSVKGKVVIDAFRLI+ ++ EPRQTTSN G LNK +IQALIHGLNRHY Sbjct: 141 VAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHY 200 Query: 197 YSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIE 256 YS+ I+Y K E KML+NLHK+ W GL + DY E + N + K M+++A+ Y+K +E Sbjct: 201 YSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVE 260 Query: 257 EEKELTEEELKTRYVGRQDPKKHLSETADETLENNIVSVLTAGVNSVAIK 306 EE ++T E+L + VG+QDPK+HL E D + +NIV L A +++V K Sbjct: 261 EEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK 310 >4O8Y-B nrPDB Length = 240 Score = 353 bits (906), Expect = 5e-98, Method: Composition-based stats. Identities = 238/238 (100%), Positives = 238/238 (100%) Query: 2 ERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDY 61 ERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDY Sbjct: 3 ERLQRLMMNSKVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDY 62 Query: 62 TVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSV 121 TVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSV Sbjct: 63 TVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSV 122 Query: 122 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLN 181 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLN Sbjct: 123 DVNTQKSFEQLNSRAVAVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLN 182 Query: 182 KANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLA 239 KANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLA Sbjct: 183 KANIQALIHGLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLA 240 >4F7O-A nrPDB Length = 257 Score = 220 bits (561), Expect = 5e-58, Method: Composition-based stats. Identities = 82/203 (40%), Positives = 121/203 (59%), Gaps = 11/203 (5%) Query: 28 YISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT--GVSVEAVDD 85 IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V+ +A Sbjct: 56 KISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAY 114 Query: 86 VFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQ 145 + A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP + Sbjct: 115 EYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTR 174 Query: 146 SVK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQAL-IHGLNRHYYSLNIDY 203 ++ GKV + AFR G + P + T LNK I+ +H + YY+L + Y Sbjct: 175 TISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNK--IEDFGVHC--KQYYALEVSY 228 Query: 204 HKTAKETKMLMNLHKEQWQSGLK 226 K++ + K+L L + W + L Sbjct: 229 FKSSLDRKLLELLWNKYWVNTLS 251 >4D10-E nrPDB Length = 334 Score = 220 bits (559), Expect = 8e-58, Method: Composition-based stats. Identities = 92/262 (35%), Positives = 140/262 (53%), Gaps = 28/262 (10%) Query: 28 YISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGT--GVSVEAVDD 85 IS++ALLKM+ H R+G +EVMGLMLG+ VD T+ ++D FA+P GT V+ +A Sbjct: 56 KISALALLKMVMHARSGGNLEVMGLMLGK-VDGETMIIMDSFALPVEGTETRVNAQAAAY 114 Query: 86 VFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQ 145 + A ++ KQ GR + +GWYHSHPG+GCWLS +DV+TQ +Q VAVV+DP + Sbjct: 115 EYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTR 174 Query: 146 SVK-GKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANIQAL-IHGLNRHYYSLNIDY 203 ++ GKV + AFR G + P + T LNK I+ +H + YY+L + Y Sbjct: 175 TISAGKVNLGAFRTYPKGYKPPDEGPSEY--QTIPLNK--IEDFGVHC--KQYYALEVSY 228 Query: 204 HKTAKETKMLMNLHKEQWQSGLK--------------MYDYEEKEESNLAATKS---MVK 246 K++ + K+L L + W + L ++D EK E + A M+ Sbjct: 229 FKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLG 288 Query: 247 IAEQYSKRIEEEKELTEEELKT 268 + K ++ + T + KT Sbjct: 289 LETHDRKSEDKLAKATRDSCKT 310 >3J8B-H nrPDB Length = 343 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 48/168 (28%), Positives = 89/168 (52%), Gaps = 11/168 (6%) Query: 21 DDTKETVYISSIALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVNVVDVFAMPQSGTGV 78 D + V I + +LK++KH + G EV+ G++LG V+D + + + F PQ Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDR-LEITNCFPFPQHTEDD 91 Query: 79 SVEAVDDV-FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAV 137 + D+V +Q +MM L+ D + VGWY S +G +++ +++Q S++ +V Sbjct: 92 A--DFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESV 148 Query: 138 AVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANI 185 ++ DPI++ +G + + A+RL T L+ + + + L KANI Sbjct: 149 VLIYDPIKTAQGSLSLKAYRL--TPKLMEVCKEKDFSPEA--LKKANI 192 >6FEC-5 nrPDB Length = 352 Score = 154 bits (390), Expect = 4e-38, Method: Composition-based stats. Identities = 48/168 (28%), Positives = 89/168 (52%), Gaps = 11/168 (6%) Query: 21 DDTKETVYISSIALLKMLKHGRA-GVPMEVM-GLMLGEFVDDYTVNVVDVFAMPQSGTGV 78 D + V I + +LK++KH + G EV+ G++LG V+D + + + F PQ Sbjct: 33 DSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDR-LEITNCFPFPQHTEDD 91 Query: 79 SVEAVDDV-FQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAV 137 + D+V +Q +MM L+ D + VGWY S +G +++ +++Q S++ +V Sbjct: 92 A--DFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRALLDSQFSYQHAIEESV 148 Query: 138 AVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTSNTGLLNKANI 185 ++ DPI++ +G + + A+RL T L+ + + + L KANI Sbjct: 149 VLIYDPIKTAQGSLSLKAYRL--TPKLMEVCKEKDFSPEA--LKKANI 192 >5CW6-A nrPDB Length = 262 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 39/149 (26%), Positives = 66/149 (44%), Gaps = 8/149 (5%) Query: 23 TKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAM---PQSGTGVS 79 V++ S A L + H + EVMGL +GE + V++ V + + V Sbjct: 4 AVNAVHLESDAFLVCMNHALSTEKEEVMGLCIGEVDTNRIVHIHSVIILRRSDKRKDRVE 63 Query: 80 VEAVDDVFQAKMMDMLKQ-TGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVA 138 + + + L + TGR VVGWYHSHP W S VDV TQ ++ ++ V Sbjct: 64 ISPEQLSAASTEAERLAEMTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVG 123 Query: 139 VV----VDPIQSVKGKVVIDAFRLIDTGA 163 ++ ++ + G+V+ F+ + Sbjct: 124 LIFSCFIEDKNTKTGRVLYTCFQSVQAQK 152 >6FJU-A nrPDB Length = 228 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 47/144 (32%), Positives = 83/144 (57%), Gaps = 6/144 (4%) Query: 26 TVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVDD 85 V I +AL K++KH + + EV GL++G+ + + D Q GT V+ +D+ Sbjct: 28 RVRIYPLALAKVVKHAASSLQREVAGLLVGKSA-GKVLEIWDAVTGEQYGTPAYVQ-LDE 85 Query: 86 VFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPIQ 145 + AK+ + L ++ ++ +VGWYHSHPG +LS D++TQK ++ + S+AVA+VVDP+ Sbjct: 86 MVMAKVAEELSKSDKNLYIVGWYHSHPGLDVFLSPTDIDTQKRYQAMFSKAVALVVDPVD 145 Query: 146 SVKGK----VVIDAFRLIDTGALI 165 K + + F++ G ++ Sbjct: 146 YAKTRRISSLKFKVFQISKEGRVV 169 >5CW3-A nrPDB Length = 255 Score = 144 bits (363), Expect = 5e-35, Method: Composition-based stats. Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 7/144 (4%) Query: 21 DDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDD--YTVNVVDVFAMPQSGTGV 78 D + + V + + + L+H + EVMGL++G F V+ + + + V Sbjct: 5 DSSLQKVELQTDVYMVCLQHALSTENFEVMGLLIGNFACGIAKISAVIILRRLDKKKDRV 64 Query: 79 SVEAVDDVFQAKMMDMLK-QTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAV 137 + + + A + L + R V+GWYHSHP S VDV TQ +++ ++ V Sbjct: 65 EISSEQLLKAAAEAERLTVELNRPMRVLGWYHSHPHITVCPSHVDVRTQATYQTMDHSFV 124 Query: 138 AVVV----DPIQSVKGKVVIDAFR 157 ++ + +S + ++ ++ F+ Sbjct: 125 GLIFSVFSEGKESKEHEIFLNCFQ 148 >6MSD-Z nrPDB Length = 324 Score = 128 bits (322), Expect = 2e-30, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 11/126 (8%) Query: 23 TKETVYISSIALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMP--QSGT 76 + V + + LL ++ H G+ G V+G++LG + ++V + FA+P + Sbjct: 5 AVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSW-QKKVLDVSNSFAVPFDEDDK 63 Query: 77 GVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRA 136 SV +D + M M K+ + +VGWYH+ P L D+ + ++ + Sbjct: 64 DDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNS 119 Query: 137 VAVVVD 142 V V++D Sbjct: 120 VLVIID 125 >5VFQ-Z nrPDB Length = 286 Score = 128 bits (321), Expect = 3e-30, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 59/126 (46%), Gaps = 11/126 (8%) Query: 23 TKETVYISSIALLKMLKH----GRAGVPMEVMGLMLGEFVDDYTVNVVDVFAMP--QSGT 76 + V + + LL ++ H G+ G V+G++LG + ++V + FA+P + Sbjct: 1 AVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSW-QKKVLDVSNSFAVPFDEDDK 59 Query: 77 GVSVEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRA 136 SV +D + M M K+ + +VGWYH+ P L D+ + ++ + Sbjct: 60 DDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPK----LHKNDIAINELMKRYCPNS 115 Query: 137 VAVVVD 142 V V++D Sbjct: 116 VLVIID 121 >6FVW-U nrPDB Length = 304 Score = 112 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 10/137 (7%) Query: 25 ETVYISSIALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVNVVDVFAMP--QSGTGVS 79 E V I+ + LL L H E +G++LG+ + T+ V + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 80 VEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAV 139 V +D + M +M K+ + ++GWYHS P L + D+ + F++ + Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQNNPLL 120 Query: 140 VVDPIQSVKGKVVIDAF 156 ++ ++ + DA+ Sbjct: 121 LIVDVKQQGVGLPTDAY 137 >3JCO-U nrPDB Length = 338 Score = 110 bits (275), Expect = 6e-25, Method: Composition-based stats. Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 10/137 (7%) Query: 25 ETVYISSIALLKMLKHGRAGVPME---VMGLMLGEFVDDYTVNVVDVFAMP--QSGTGVS 79 E V I+ + LL L H E +G++LG+ + T+ V + FA+P + Sbjct: 6 EKVTIAPLVLLSALDHYERTQTKENKRCVGVILGD-ANSSTIRVTNSFALPFEEDEKNSD 64 Query: 80 VEAVDDVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAV 139 V +D + M +M K+ + ++GWYHS P L + D+ + F++ + Sbjct: 65 VWFLDHNYIENMNEMCKKINAKEKLIGWYHSGPK----LRASDLKINELFKKYTQNNPLL 120 Query: 140 VVDPIQSVKGKVVIDAF 156 ++ ++ + DA+ Sbjct: 121 LIVDVKQQGVGLPTDAY 137 >3J8B-F nrPDB Length = 327 Score = 68.6 bits (166), Expect = 3e-12, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 9/132 (6%) Query: 27 VYISSIALLKMLKHGRAGVP--MEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVD 84 V + + L ++ V+G +LG VD ++V V + F++P + + V AVD Sbjct: 92 VRLHPVILASIVDSYERRNEGAARVIGTLLG-TVDKHSVEVTNCFSVPHNESEDEV-AVD 149 Query: 85 DVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPI 144 F M ++ K+ +++++GWY + G SV + + + + + + VD Sbjct: 150 MEFAKNMYELHKKVSPNELILGWYAT--GHDITEHSVLI--HEYYSREAPNPIHLTVD-T 204 Query: 145 QSVKGKVVIDAF 156 G++ I A+ Sbjct: 205 SLQNGRMSIKAY 216 >5A5T-F nrPDB Length = 364 Score = 67.9 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 61/132 (46%), Gaps = 9/132 (6%) Query: 27 VYISSIALLKMLKHGRAGVP--MEVMGLMLGEFVDDYTVNVVDVFAMPQSGTGVSVEAVD 84 V + + L ++ V+G +LG VD ++V V + F++P + + V AVD Sbjct: 99 VRLHPVILASIVDSYERRNEGAARVIGTLLG-TVDKHSVEVTNCFSVPHNESEDEV-AVD 156 Query: 85 DVFQAKMMDMLKQTGRDQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVAVVVDPI 144 F M ++ K+ +++++GWY + G SV + + + + + + VD Sbjct: 157 MEFAKNMYELHKKVSPNELILGWYAT--GHDITEHSVLI--HEYYSREAPNPIHLTVD-T 211 Query: 145 QSVKGKVVIDAF 156 G++ I A+ Sbjct: 212 SLQNGRMSIKAY 223 >4KIT-C nrPDB Length = 278 Score = 36.7 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 22/125 (17%), Positives = 45/125 (36%), Gaps = 11/125 (8%) Query: 43 AGVPMEVMGLMLGEF--VDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGR 100 + + ++ G + G + + + +PQ GT +V + Q + + + Sbjct: 61 SDLRAQIAGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYL-------K 113 Query: 101 DQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLNSRAVA--VVVDPIQSVKGKVVIDAFRL 158 + +GW H+ P LS DV T N ++ G + A++L Sbjct: 114 EMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIIITCSFTPGSCTLTAYKL 173 Query: 159 IDTGA 163 +G Sbjct: 174 TPSGY 178 >2P87-A nrPDB Length = 273 Score = 33.6 bits (75), Expect = 0.11, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 47/128 (36%), Gaps = 17/128 (13%) Query: 43 AGVPMEVMGLMLGEF--VDDYTVNVVDVFAMPQSGTGVSVEAVDDVFQAKMMDMLKQTGR 100 + + ++ G M G + + + +PQ+G+ V + +++ R Sbjct: 55 SDLRTQIAGFMYGVSPPDNPQVKEIRCIVLVPQTGSHQQVNLPTQLPDHELL-------R 107 Query: 101 DQMVVGWYHSHPGFGCWLSSVDVNTQKSFEQLN-----SRAVAVVVDPIQSVKGKVVIDA 155 D +GW H+ P LS DV T N + V + G V + A Sbjct: 108 DFEPLGWMHTQPNELPQLSPQDVTTHAKLLTDNISWDGEKTVMITC---SFTPGSVSLTA 164 Query: 156 FRLIDTGA 163 ++L +G Sbjct: 165 YKLTPSGY 172 >4DVY-P nrPDB Length = 876 Score = 32.4 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 215 NLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKEL---TEEELKTRYV 271 NL + GL + + + + L++ K + A ++K + E K E + + + Sbjct: 560 NLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDL 619 Query: 272 GRQDPKK-HLSETADETLEN 290 + K+ HL + ++ LE+ Sbjct: 620 EKSLRKREHLEKEVEKKLES 639 >4DVZ-A nrPDB Length = 569 Score = 31.7 bits (70), Expect = 0.41, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 36/80 (45%), Gaps = 4/80 (5%) Query: 215 NLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKEL---TEEELKTRYV 271 NL + GL + + + + L++ K + A ++K + E K E + + + Sbjct: 300 NLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDL 359 Query: 272 GRQDPKK-HLSETADETLEN 290 + K+ HL + ++ LE+ Sbjct: 360 EKSLRKREHLEKEVEKKLES 379 >3JAX-A nrPDB Length = 974 Score = 29.7 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 36/90 (40%), Gaps = 7/90 (7%) Query: 204 HKTAKETKMLMNLHKEQ------WQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEE 257 + E KM+ L ++ + D EE+ + + + ++ ++R+E+ Sbjct: 880 RRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLED 939 Query: 258 EKELTEEELKTRYVGRQDPKKHLSETADET 287 E+E+ E L + +D L D+ Sbjct: 940 EEEMNAE-LTAKKRKLEDECSELKRDIDDL 968 >4RM9-A nrPDB Length = 587 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 31/137 (22%), Positives = 52/137 (37%), Gaps = 18/137 (13%) Query: 140 VVDPIQSVKGKVVIDAFRLIDTGALINNLEP------RQTTSNTGLLNKANIQALIHGLN 193 V+ PI V A RL ++ R+ +T + + QA Sbjct: 257 VIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAR---EE 313 Query: 194 RHYYSLNIDYHKTAKETKMLMNLHKEQWQSG-----LKMYDYEEKEESNLAATKSMVKIA 248 +H L +T K+ + + KEQ L++ DYEEK + ++ A Sbjct: 314 KHQKQLERQQLETEKKRRETVEREKEQMMREKEELMLRLQDYEEKTKKAERELSEQIQRA 373 Query: 249 EQYSKRIEEEKELTEEE 265 Q +EEE++ +EE Sbjct: 374 LQ----LEEERKRAQEE 386 >6HIX-AK nrPDB Length = 342 Score = 29.4 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 50/140 (35%), Gaps = 11/140 (7%) Query: 155 AFRLIDTGALIN--NLEPRQTTSNTGLLNKANIQALIHGLNRHYYSLNIDYHKTAKETKM 212 F +DT ++ +Q T + +++ R L Sbjct: 190 CFIGVDTPYSSPVKDMTEQQYTEECERYRRIHMEQYTTLRQRE---LEEAPLIERLHRPN 246 Query: 213 LMNLHKEQWQSGLK---MYDYEEKEESNLAATKSMV---KIAEQYSKRIEEEKELTEEEL 266 + L EQ + GL+ + D + L+ + ++A +Y K++T EE+ Sbjct: 247 MSPLTDEQIEEGLRDPCLLDTLWRASHPLSPYHRDLRERELARRYLNARGWVKDMTPEEM 306 Query: 267 KTRYVGRQDPKKHLSETADE 286 + ++ + P+ + DE Sbjct: 307 RIVFMNYRLPEGEKRKQMDE 326 >6ID1-L nrPDB Length = 802 Score = 29.0 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 211 KMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVK-IAEQYSKRIEEEKEL 261 K L +L + Q+ L++ +EE ++ +A ++ + E ++ E EKEL Sbjct: 733 KQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLKEDVQRQQEREKEL 784 >6DGB-A nrPDB Length = 143 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 32/107 (29%), Gaps = 7/107 (6%) Query: 12 KVGSADTGRDDTKETVYISSIALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVVDVFAM 71 +VGS G+ + A + +++H V L + V D Sbjct: 41 EVGSGLNGKRPKLRRILSDPDARVIVVEHRDRLARFGVEHLEAALSAQGRRIVVAD---- 96 Query: 72 PQSGTGVSVEAVDDVFQ---AKMMDMLKQTGRDQMVVGWYHSHPGFG 115 P T V + +V A++ R V PG G Sbjct: 97 PGETTDDLVCDMIEVLTGMCARLYGRRGARNRAMRAVTEAKREPGAG 143 >4MCR-A nrPDB Length = 757 Score = 27.4 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 27/61 (44%) Query: 210 TKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQYSKRIEEEKELTEEELKTR 269 K ++ + +M Y +S +A K+ +IA ++S+R+++ + L+ Sbjct: 612 RKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASKFSERLQDFDKSNPIVLRMM 671 Query: 270 Y 270 Sbjct: 672 N 672 >1MQS-A nrPDB Length = 671 Score = 27.4 bits (59), Expect = 7.9, Method: Composition-based stats. Identities = 26/152 (17%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 138 AVVVDPIQSVKGKVVIDAFRLIDTGALINNLEPRQTTS-------NTGLLNKANIQALIH 190 +++D + V+ L+ G +++L + + K NI +++ Sbjct: 60 VLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVN 119 Query: 191 GLNRHYYSLNIDYHKTAKETKMLMNLHKEQWQSGLKMYDYEEKEESNLAATKSMVKIAEQ 250 L YS ++ +L +L ++ +G + + ++ +Q Sbjct: 120 DLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITG---------------KSDKIKQVYDQ 164 Query: 251 YSKRIEEEKELTEEELKTRYVGRQDPKKHLSE 282 Y I E EL E+ Y+ DPK E Sbjct: 165 YLDFIVTEPELFSLEISNAYLTLNDPKTTEEE 196 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.126 0.314 Lambda K H 0.267 0.0379 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,723,278 Number of Sequences: 36641 Number of extensions: 341823 Number of successful extensions: 1106 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 44 Number of HSP's successfully gapped in prelim test: 31 Number of HSP's that attempted gapping in prelim test: 1018 Number of HSP's gapped (non-prelim): 76 length of query: 306 length of database: 10,336,785 effective HSP length: 97 effective length of query: 209 effective length of database: 6,782,608 effective search space: 1417565072 effective search space used: 1417565072 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 59 (27.4 bits)