BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P43246 (934 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3THY-A nrPDB 1931 0.0 1EWR-A nrPDB 281 8e-76 1NNE-A nrPDB 281 1e-75 5AKB-A nrPDB 276 4e-74 3THX-B nrPDB 247 2e-65 5X9W-A nrPDB 214 1e-55 5TXT-B nrPDB 32 0.96 5CA0-F nrPDB 32 1.1 3JCR-F nrPDB 32 1.6 3HBA-A nrPDB 31 2.4 5J70-A nrPDB 30 4.0 4NHO-A nrPDB 30 4.8 2UVP-A nrPDB 30 4.8 4A2Q-A nrPDB 30 5.5 4A2W-A nrPDB 30 5.6 3E70-C nrPDB 30 6.0 4A36-A nrPDB 29 8.6 3A4L-A nrPDB 29 9.8 >3THY-A nrPDB Length = 934 Score = 1931 bits (5002), Expect = 0.0, Method: Compositional matrix adjust. Identities = 934/934 (100%), Positives = 934/934 (100%) Query: 1 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT 60 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT Sbjct: 1 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT 60 Query: 61 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA 120 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA Sbjct: 61 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA 120 Query: 121 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD 180 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD Sbjct: 121 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD 180 Query: 181 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD 240 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD Sbjct: 181 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD 240 Query: 241 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM 300 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM Sbjct: 241 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM 300 Query: 301 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL 360 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL Sbjct: 301 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL 360 Query: 361 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA 420 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA Sbjct: 361 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA 420 Query: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE Sbjct: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480 Query: 481 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS 540 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS Sbjct: 481 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS 540 Query: 541 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA 600 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA Sbjct: 541 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA 600 Query: 601 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD 660 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD Sbjct: 601 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD 660 Query: 661 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK 720 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK Sbjct: 661 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK 720 Query: 721 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF 780 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF Sbjct: 721 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF 780 Query: 781 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV 840 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV Sbjct: 781 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV 840 Query: 841 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS 900 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS Sbjct: 841 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS 900 Query: 901 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT 934 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT Sbjct: 901 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT 934 >1EWR-A nrPDB Length = 649 Score = 281 bits (720), Expect = 8e-76, Method: Compositional matrix adjust. Identities = 189/596 (31%), Positives = 301/596 (50%), Gaps = 57/596 (9%) Query: 259 PEMENQVAVS-SLSAVIKFLELLSDDSNFGQFELTTFDF---SQYMKLDIAAVRALNLFQ 314 PE E +A+ + A++ + + + G L F F +M+L A +RAL +F Sbjct: 93 PEGEGPLALRRARGALLAY----AQRTQGGALSLQPFRFYDPGAFMRLPEATLRALEVF- 147 Query: 315 GSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQ 374 E G +L ++L++ +T G+RL+ W++ PL+D+ +E RL+ VE FV + LR+ Sbjct: 148 ---EPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARLDRVEGFVREGALRE 204 Query: 375 TLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLA 434 ++ LL R DL RLA + + A+ +D L + + LP + L + G Sbjct: 205 GVRR-LLYRLADLERLATRLELGRASPKDLGALRRSLQILPELRALLGEEVGL------- 256 Query: 435 VFVTPLTDLRSDFSKFQEMIETTL--DMDQVENHEFLVKPSFDPNLSELREIMNDLEKKM 492 D S +E +E L D + L++ +DP+L LR + Sbjct: 257 ----------PDLSPLKEELEAALVEDPPLKVSEGGLIREGYDPDLDALRAAHREGVAYF 306 Query: 493 QSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFT 552 G+ +K+ +A FGYY VT + R K + V K+ ++T Sbjct: 307 LELEERERERTGI---PTLKVGYNAVFGYYLEVTRPYYE--RVPKEYRPVQTLKDRQRYT 361 Query: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612 ++ E + + ++ + E+ + E ++ +LA+LD + A V+ Sbjct: 362 LPEMKEKEREVYRLEALIRRREEEVFLEVRERAKRQAEALREAARILAELDVYAALAEVA 421 Query: 613 NGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFH---IITG 669 YVRP + R+ ++A RH VE + E F+PND+ +M H +ITG Sbjct: 422 --VRYGYVRP----RFGDRLQIRAGRHPVVERRTE--FVPNDL------EMAHELVLITG 467 Query: 670 PNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEM 729 PNM GKST++RQT +I L+AQ+G FVP E A + + D I R+GA D G STFM EM Sbjct: 468 PNMAGKSTFLRQTALIALLAQVGSFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEM 527 Query: 730 LETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTA 789 E A IL+ AT++SL+++DE+GRGTS+ DG +A A++E + + A+ +FATH+ ELTA Sbjct: 528 EEVALILKEATENSLVLLDEVGRGTSSLDGVAIATAVAEALHER-RAYTLFATHYFELTA 586 Query: 790 LANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAK 845 L +P + NLHV A L +QV G +S+G+ VA +A PK V+ A+ Sbjct: 587 LG--LPRLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARAR 640 >1NNE-A nrPDB Length = 765 Score = 281 bits (719), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 189/596 (31%), Positives = 301/596 (50%), Gaps = 57/596 (9%) Query: 259 PEMENQVAVS-SLSAVIKFLELLSDDSNFGQFELTTFDF---SQYMKLDIAAVRALNLFQ 314 PE E +A+ + A++ + + + G L F F +M+L A +RAL +F Sbjct: 209 PEGEGPLALRRARGALLAY----AQRTQGGALSLQPFRFYDPGAFMRLPEATLRALEVF- 263 Query: 315 GSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQ 374 E G +L ++L++ +T G+RL+ W++ PL+D+ +E RL+ VE FV + LR+ Sbjct: 264 ---EPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARLDRVEGFVREGALRE 320 Query: 375 TLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLA 434 ++ LL R DL RLA + + A+ +D L + + LP + L + G Sbjct: 321 GVRR-LLYRLADLERLATRLELGRASPKDLGALRRSLQILPELRALLGEEVGL------- 372 Query: 435 VFVTPLTDLRSDFSKFQEMIETTL--DMDQVENHEFLVKPSFDPNLSELREIMNDLEKKM 492 D S +E +E L D + L++ +DP+L LR + Sbjct: 373 ----------PDLSPLKEELEAALVEDPPLKVSEGGLIREGYDPDLDALRAAHREGVAYF 422 Query: 493 QSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFT 552 G+ +K+ +A FGYY VT + R K + V K+ ++T Sbjct: 423 LELEERERERTGI---PTLKVGYNAVFGYYLEVTRPYYE--RVPKEYRPVQTLKDRQRYT 477 Query: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612 ++ E + + ++ + E+ + E ++ +LA+LD + A V+ Sbjct: 478 LPEMKEKEREVYRLEALIRRREEEVFLEVRERAKRQAEALREAARILAELDVYAALAEVA 537 Query: 613 NGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFH---IITG 669 YVRP + R+ ++A RH VE + E F+PND+ +M H +ITG Sbjct: 538 --VRYGYVRP----RFGDRLQIRAGRHPVVERRTE--FVPNDL------EMAHELVLITG 583 Query: 670 PNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEM 729 PNM GKST++RQT +I L+AQ+G FVP E A + + D I R+GA D G STFM EM Sbjct: 584 PNMAGKSTFLRQTALIALLAQVGSFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEM 643 Query: 730 LETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTA 789 E A IL+ AT++SL+++DE+GRGTS+ DG +A A++E + + A+ +FATH+ ELTA Sbjct: 644 EEVALILKEATENSLVLLDEVGRGTSSLDGVAIATAVAEALHER-RAYTLFATHYFELTA 702 Query: 790 LANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAK 845 L +P + NLHV A L +QV G +S+G+ VA +A PK V+ A+ Sbjct: 703 LG--LPRLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARAR 756 >5AKB-A nrPDB Length = 800 Score = 276 bits (705), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 183/560 (32%), Positives = 285/560 (50%), Gaps = 40/560 (7%) Query: 302 LDIAAVRALNLFQ---GSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEE 358 +D A R L + Q G E+T LA++L+ TP G R++ +W+ P+ D + E Sbjct: 269 MDAATRRNLEITQNLAGGAENT-----LASVLDSTVTPMGSRMLKRWLHMPVRDTRVLLE 323 Query: 359 RLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVI 418 R + A + LQ +LR+ DL R+ + + A +D R+ QLP + Sbjct: 324 RQQTIGAL---QDFTAGLQP-VLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELR 379 Query: 419 QALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVK------P 472 LE V P+ LR +F E+ L+ ++ LV+ Sbjct: 380 AQLE-----------TVDSAPVQALREKMGEFAEL-RDLLERAIIDTPPVLVRDGGVIAS 427 Query: 473 SFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKV 532 ++ L E R + + ++ + GLD +K+ +A GYY +++ + + Sbjct: 428 GYNEELDEWRALADGATDYLERLEVRERERTGLD---TLKVGFNAVHGYYIQISRGQSHL 484 Query: 533 LRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPM 592 N+ KN ++ +L ++ +K + + + +E+ ++ ++E + Sbjct: 485 --APINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEAL 542 Query: 593 QTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIP 652 Q LA+LD +V+ A + Y P ++K RI RH VE FI Sbjct: 543 QQSASALAELDVLVNLAE--RAYTLNYTSPTFIDKPGIRI--TEGRHPVVEQVLNEPFIA 598 Query: 653 NDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARV 712 N + ++M IITGPNMGGKSTY+RQT +I LMA IG +VP + E+ +D I RV Sbjct: 599 NPLNLSPQRRML-IITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRV 657 Query: 713 GAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIAT 772 GA D G STFM EM ETA+IL +AT+ SL+++DE+GRGTSTYDG LAWA++E +A Sbjct: 658 GAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWAVAENLAN 717 Query: 773 KIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAE 832 KI A +FATH+ ELT L ++ V N+H+ AL +T+ ++ V+ G +S+G+ VA Sbjct: 718 KIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAA 777 Query: 833 LANFPKHVIECAKQKALELE 852 LA PK VI+ A+QK ELE Sbjct: 778 LAGVPKEVIKRARQKLRELE 797 >3THX-B nrPDB Length = 918 Score = 247 bits (630), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 211/754 (27%), Positives = 350/754 (46%), Gaps = 93/754 (12%) Query: 145 IGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGG 204 IG+VGV Q G DS F D+ S LE + + P E +LP Sbjct: 172 IGIVGV-------QPATGEVVFDS---------FQDSASRSELETRMSSLQPVELLLPSA 215 Query: 205 ---ETAGDMGKLRQI-IQRGGILITERKKADFSTKDIYQDLNRLLKGK----KGEQMNSA 256 +T + + + +Q I + F +Q + KG Q+ S Sbjct: 216 LSEQTEALIHRATSVSVQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISG 275 Query: 257 VLPEMENQVAVSSLSAVIKFLE------LLSDDSNFGQFELTTFDFSQYMKLDIAAVRAL 310 ++ +E V + SL+A+IK+L+ +LS NF Q ++M ++ +R L Sbjct: 276 IV-NLEKPV-ICSLAAIIKYLKEFNLEKMLSKPENFKQLSSKM----EFMTINGTTLRNL 329 Query: 311 NLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDA 370 + Q D SL +L+ KT G+R + +W+ QPL+ I RL+ V + Sbjct: 330 EILQNQT-DMKTKGSLLWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSE 388 Query: 371 ELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKH-Q 429 E+ LR+ PD+ R + + Q+ + + + + L + QA+ H Q Sbjct: 389 SSVFGQIENHLRKLPDIERGLCSIYHKKCSTQEFFLIVKTLYHLKSEFQAIIPAVNSHIQ 448 Query: 430 KLLLAVFVTPLTDLRSDFSKFQEMI--ETTLDMDQVENHEFLVK-PSFDPNLSELREIMN 486 LL + + +L S + +++ + D+ E + L P E++ +++ Sbjct: 449 SDLLRTVILEIPELLSPVEHYLKILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVID 508 Query: 487 DLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQK 546 ++ +Q ++I + SAQ+ VT ++ + KN + I Sbjct: 509 EIRMHLQEI-------------RKILKNPSAQY-----VTVSGQEFMIEIKNSAVSCIPT 550 Query: 547 NGVKFTNSKLTS------LNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDV-- 598 + VK ++K S + E Y E+ E ++ + E +L Sbjct: 551 DWVKVGSTKAVSRFHSPFIVENYRHLNQLREQLVLDCSAEWLDFLEKFSEHYHSLCKAVH 610 Query: 599 -LAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEV----QDEIAFIPN 653 LA +D + S A V+ Y RP + E + +I++K RH ++V QD+ ++PN Sbjct: 611 HLATVDCIFSLAKVAKQGD--YCRPTVQE--ERKIVIKNGRHPVIDVLLGEQDQ--YVPN 664 Query: 654 DVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVG 713 + +D + IITGPNMGGKS+YI+Q +I +MAQIG +VP E A + IVD I R+G Sbjct: 665 NTDLSEDSERVMIITGPNMGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMG 724 Query: 714 AGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATK 773 A D+ KG STFM E+ +TA I+R AT SL+I+DELGRGTST+DG +A+A EY Sbjct: 725 AADNIYKGRSTFMEELTDTAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRD 784 Query: 774 IGAFCMFATHFHELTAL-ANQIPTVNNLHVTALTTEET--------------LTMLYQVK 818 + + +F TH+ + L N V N H+ L +E+ +T LYQ+ Sbjct: 785 VKSLTLFVTHYPPVCELEKNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQIT 844 Query: 819 KGVCDQSFGIHVAELANFPKHVIECAKQKALELE 852 +G+ +S+G++VA+LA+ P +++ A K+ ELE Sbjct: 845 RGIAARSYGLNVAKLADVPGEILKKAAHKSKELE 878 >5X9W-A nrPDB Length = 816 Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 183/615 (29%), Positives = 287/615 (46%), Gaps = 73/615 (11%) Query: 262 ENQVAVSSLSAVIKFLELLSD--DSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVED 319 E+ V++ + A++ ++ L + + L T SQY+ +D A R L + Q Sbjct: 227 EHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETD--SQYIGMDAATRRNLEITQTLSGK 284 Query: 320 TTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQED 379 T +L ++L+ C T G RL+ W+ PL ++ I R V A E Q Sbjct: 285 KT--PTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEAVTALESQYEPLQCH--- 339 Query: 380 LLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTP 439 L+ D+ R+A + A +D L + +L + L + L AVF P Sbjct: 340 -LKSIADIERIAARIAVGNARPRDLASLRDSLFELAQI--DLSATGSSLLETLKAVF--P 394 Query: 440 LTDLRSDFSKFQEMIETTLDMD--QVENHEFLVKPSFDPNLSELREIMN-------DLE- 489 T ++ K M E ++ + V NH F P L ELR I N DLE Sbjct: 395 ETLPVAETLKAAVMPEPSVWLKDGNVINH------GFHPELDELRRIQNHGDEFLLDLEA 448 Query: 490 KKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVT----------CKEEKVLRNNKNF 539 K+ + T +S +K++ + G+Y ++ + + L+N + F Sbjct: 449 KERERTGLST-----------LKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERF 497 Query: 540 STVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNI--SSGYVEPMQTLND 597 T +++ F + LT+ ++ K + D ++K + D Sbjct: 498 ITPELKA----FEDKVLTAQDQALALEKQLF----DGVLKNLRTALPQLQKAAKAAAALD 549 Query: 598 VLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYF 657 VL+ A+ A N +VRP + + ++ RH VE Q F N Sbjct: 550 VLSTFSAL---AKERN-----FVRPEFADYPV--VHIENGRHPVVEQQVR-HFTANHTDL 598 Query: 658 EKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDS 717 + K ++TGPNMGGKSTY+RQ +IVL+A GCFVP ++A + VD I R+GA D Sbjct: 599 DH-KHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRIGASDD 657 Query: 718 QLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAF 777 STFM EM ETA IL AT+ S++++DE+GRGTST+DG LA AI+E++ K +F Sbjct: 658 LASNRSTFMVEMSETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSF 717 Query: 778 CMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFP 837 +FATH+ ELT L N+H++AL + L+Q++ G +S+GI VA+LA P Sbjct: 718 SLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLP 777 Query: 838 KHVIECAKQKALELE 852 ++ A++ LE Sbjct: 778 VRALKAAQKHLNGLE 792 >5TXT-B nrPDB Length = 491 Score = 32.3 bits (72), Expect = 0.96, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 6/61 (9%) Query: 369 DAELRQTLQEDLLRRFPDLNRLAKKF-----QRQAANLQ-DCYRLYQGINQLPNVIQALE 422 D+EL++ + R F ++NRLAK+F QR+A + C Y +++ P V+ A+ Sbjct: 21 DSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCSNDYLALSKHPEVLDAMH 80 Query: 423 K 423 K Sbjct: 81 K 81 >5CA0-F nrPDB Length = 384 Score = 32.3 bits (72), Expect = 1.1, Method: Compositional matrix adjust. Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 7/107 (6%) Query: 479 SELREIMNDLEKKMQSTLISA--ARDLGLDPG-KQIKLDSSAQFGYYFRVTCKEEKVLR- 534 SE E+++ ++++ Q +I + L L+PG ++ + S + + + E VLR Sbjct: 164 SEASELLDFIDEQGQVHVIQKYLEKPLLLEPGHRKFDIRSWVLVDHLYNIYLYREGVLRT 223 Query: 535 NNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEI 581 +++ +++ + Q TN + +EY+KN YEE + +E Sbjct: 224 SSEPYNSANFQDKTCHLTNH---CIQKEYSKNYGRYEEGNEMFFEEF 267 >3JCR-F nrPDB Length = 820 Score = 31.6 bits (70), Expect = 1.6, Method: Compositional matrix adjust. Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 22/109 (20%) Query: 734 SILRSATKDSLIIIDELGRGTSTYD-----GFGLAWAISEYIATKIGAFCMFATHFHELT 788 S L++ KD L+ D GRG D + +A I +YI +IG T Sbjct: 708 SNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIH-RIGR-----------T 755 Query: 789 ALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFP 837 A + + + +T LT E++ + Y++K+ + + ELAN P Sbjct: 756 GRAGK----SGVAITFLTKEDS-AVFYELKQAILESPVSSCPPELANHP 799 >3HBA-A nrPDB Length = 334 Score = 31.2 bits (69), Expect = 2.4, Method: Compositional matrix adjust. Identities = 25/79 (31%), Positives = 37/79 (46%), Gaps = 16/79 (20%) Query: 759 GFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVK 818 G G +A+S+ IA K+ C A H A + LH E+ L++L Sbjct: 211 GRGFGYAVSKEIALKLKEVC--AIH-------AEAFSSAEFLHGPVTLVEKKLSIL---- 257 Query: 819 KGVC--DQSFGIHVAELAN 835 VC D+S+G HV ++AN Sbjct: 258 -DVCIRDESYGSHVEQIAN 275 >5J70-A nrPDB Length = 271 Score = 30.4 bits (67), Expect = 4.0, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 9/91 (9%) Query: 830 VAELANFPKHVIECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLS 889 + + N + + E L ++ F+ GE+ YD M AAK C E E+ K I E L Sbjct: 19 ILKFGNLKEILDELIADGTLPVKSFEKYGET--YDEMMEAAKDCVHEEEKNRKEILEKLE 76 Query: 890 KVKQMPFTEMSEENITIKLKQLKAEVIAKNN 920 K + +K ++KAE K+N Sbjct: 77 K-------HATAYRAKLKSGEIKAENQPKDN 100 >4NHO-A nrPDB Length = 488 Score = 30.0 bits (66), Expect = 4.8, Method: Compositional matrix adjust. Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 22/109 (20%) Query: 734 SILRSATKDSLIIIDELGRGTSTYD-----GFGLAWAISEYIATKIGAFCMFATHFHELT 788 S L++ KD L+ D GRG D + +A I +YI +IG T Sbjct: 376 SNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIH-RIGR-----------T 423 Query: 789 ALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFP 837 A + + + +T LT E++ + Y++K+ + + ELAN P Sbjct: 424 GRAGK----SGVAITFLTKEDS-AVFYELKQAILESPVSSCPPELANHP 467 >2UVP-A nrPDB Length = 186 Score = 30.0 bits (66), Expect = 4.8, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%) Query: 26 MPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMN- 84 + E+P +V F+ FY + + LA E+ + ++G + L++++LSK+ Sbjct: 80 LKERPLLSVIDFNASSFYPKNDANLSLATIEMTYQNPMFWHVGKIENEGLKTILLSKIPS 139 Query: 85 ----FESFVKDLLLVRQY 98 FE +D LL++++ Sbjct: 140 FLWLFEELKEDCLLLKEH 157 >4A2Q-A nrPDB Length = 797 Score = 30.0 bits (66), Expect = 5.5, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 884 IQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNE 925 + EF + VK P+TE+ E+++T K ++ + E+IA + NE Sbjct: 571 LTEFFTNVKNGPYTEL-EQHLTAKFQEKEPELIALSKDETNE 611 >4A2W-A nrPDB Length = 936 Score = 29.6 bits (65), Expect = 5.6, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 884 IQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNE 925 + EF + VK P+TE+ E+++T K ++ + E+IA + NE Sbjct: 571 LTEFFTNVKNGPYTEL-EQHLTAKFQEKEPELIALSKDETNE 611 >3E70-C nrPDB Length = 328 Score = 29.6 bits (65), Expect = 6.0, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 18/27 (66%) Query: 856 YIGESQGYDIMEPAAKKCYLEREQGEK 882 ++G QGYD + P K+ +LER GE+ Sbjct: 300 FVGVGQGYDDLRPFEKEWFLERIFGEE 326 >4A36-A nrPDB Length = 556 Score = 29.3 bits (64), Expect = 8.6, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 884 IQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNE 925 + EF + VK P+TE+ E+++T K ++ + E+IA + NE Sbjct: 330 LTEFFTNVKNGPYTEL-EQHLTAKFQEKEPELIALSKDETNE 370 >3A4L-A nrPDB Length = 260 Score = 28.9 bits (63), Expect = 9.8, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 34/52 (65%), Gaps = 1/52 (1%) Query: 337 QGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQED-LLRRFPDL 387 + +++V+++IK +DK++I+E + L + F++ + + + D +L+ F DL Sbjct: 197 ETRKIVSEYIKSKKLDKDKIKEVVELRKEFLKKIKKMEEVDADRVLKEFKDL 248 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3THY-A nrPDB 1484 0.0 3THX-B nrPDB 803 0.0 5AKB-A nrPDB 663 0.0 5X9W-A nrPDB 663 0.0 1NNE-A nrPDB 639 0.0 1EWR-A nrPDB 638 0.0 Sequences not found previously or not previously below threshold: 1XDV-A nrPDB 36 0.080 5OVF-A nrPDB 36 0.082 3QB5-K nrPDB 36 0.12 4B0S-A nrPDB 34 0.27 4A2W-A nrPDB 33 0.57 4A2Q-A nrPDB 33 0.57 4A36-A nrPDB 33 0.59 4P9F-A nrPDB 32 1.1 2UVP-A nrPDB 31 2.0 4N4N-A nrPDB 31 3.9 2V3C-C nrPDB 30 4.0 6CON-A nrPDB 30 6.0 4FIN-A nrPDB 30 6.4 4B3J-A nrPDB 29 8.3 CONVERGED! >3THY-A nrPDB Length = 934 Score = 1484 bits (3841), Expect = 0.0, Method: Composition-based stats. Identities = 934/934 (100%), Positives = 934/934 (100%) Query: 1 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT 60 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT Sbjct: 1 MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKT 60 Query: 61 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA 120 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA Sbjct: 61 QGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLA 120 Query: 121 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD 180 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD Sbjct: 121 YKASPGNLSQFEDILFGNNDMSASIGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPD 180 Query: 181 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD 240 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD Sbjct: 181 NDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQD 240 Query: 241 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM 300 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM Sbjct: 241 LNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYM 300 Query: 301 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL 360 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL Sbjct: 301 KLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERL 360 Query: 361 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA 420 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA Sbjct: 361 NLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQA 420 Query: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE Sbjct: 421 LEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSE 480 Query: 481 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS 540 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS Sbjct: 481 LREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFS 540 Query: 541 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA 600 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA Sbjct: 541 TVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLA 600 Query: 601 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD 660 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD Sbjct: 601 QLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKD 660 Query: 661 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK 720 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK Sbjct: 661 KQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLK 720 Query: 721 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF 780 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF Sbjct: 721 GVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMF 780 Query: 781 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV 840 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV Sbjct: 781 ATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHV 840 Query: 841 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS 900 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS Sbjct: 841 IECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMS 900 Query: 901 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT 934 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT Sbjct: 901 EENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT 934 >3THX-B nrPDB Length = 918 Score = 803 bits (2074), Expect = 0.0, Method: Composition-based stats. Identities = 209/752 (27%), Positives = 348/752 (46%), Gaps = 89/752 (11%) Query: 145 IGVVGVKMSAVDGQRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGG 204 IG+VGV Q G DS F D+ S LE + + P E +LP Sbjct: 172 IGIVGV-------QPATGEVVFDS---------FQDSASRSELETRMSSLQPVELLLPSA 215 Query: 205 ---ETAGDMGKLRQI-IQRGGILITERKKADFSTKDIYQDLNRLLKGK----KGEQMNSA 256 +T + + + +Q I + F +Q + KG Q+ S Sbjct: 216 LSEQTEALIHRATSVSVQDDRIRVERMDNIYFEYSHAFQAVTEFYAKDTVDIKGSQIISG 275 Query: 257 VLPEMENQVAVSSLSAVIKFL------ELLSDDSNFGQFELTTFDFSQYMKLDIAAVRAL 310 ++ +E V + SL+A+IK+L ++LS NF Q ++M ++ +R L Sbjct: 276 IV-NLEKPV-ICSLAAIIKYLKEFNLEKMLSKPENFKQLSSKM----EFMTINGTTLRNL 329 Query: 311 NLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDA 370 + Q D SL +L+ KT G+R + +W+ QPL+ I RL+ V + Sbjct: 330 EILQNQT-DMKTKGSLLWVLDHTKTSFGRRKLKKWVTQPLLKLREINARLDAVSEVLHSE 388 Query: 371 ELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKH-Q 429 E+ LR+ PD+ R + + Q+ + + + + L + QA+ H Q Sbjct: 389 SSVFGQIENHLRKLPDIERGLCSIYHKKCSTQEFFLIVKTLYHLKSEFQAIIPAVNSHIQ 448 Query: 430 KLLLAVFVTPLTDLRSDFSKFQEMI--ETTLDMDQVENHEFLVK-PSFDPNLSELREIMN 486 LL + + +L S + +++ + D+ E + L P E++ +++ Sbjct: 449 SDLLRTVILEIPELLSPVEHYLKILNEQAAKVGDKTELFKDLSDFPLIKKRKDEIQGVID 508 Query: 487 DLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQK 546 ++ +Q ++I + SAQ+ VT ++ + KN + I Sbjct: 509 EIRMHLQEI-------------RKILKNPSAQY-----VTVSGQEFMIEIKNSAVSCIPT 550 Query: 547 NGVKFTNSKLTS------LNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDV-- 598 + VK ++K S + E Y E+ E ++ + E +L Sbjct: 551 DWVKVGSTKAVSRFHSPFIVENYRHLNQLREQLVLDCSAEWLDFLEKFSEHYHSLCKAVH 610 Query: 599 -LAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQD--EIAFIPNDV 655 LA +D + S A V+ Y RP + E + +I++K RH ++V + ++PN+ Sbjct: 611 HLATVDCIFSLAKVAKQGD--YCRPTVQE--ERKIVIKNGRHPVIDVLLGEQDQYVPNNT 666 Query: 656 YFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAG 715 +D + IITGPNMGGKS+YI+Q +I +MAQIG +VP E A + IVD I R+GA Sbjct: 667 DLSEDSERVMIITGPNMGGKSSYIKQVALITIMAQIGSYVPAEEATIGIVDGIFTRMGAA 726 Query: 716 DSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIG 775 D+ KG STFM E+ +TA I+R AT SL+I+DELGRGTST+DG +A+A EY + Sbjct: 727 DNIYKGRSTFMEELTDTAEIIRKATSQSLVILDELGRGTSTHDGIAIAYATLEYFIRDVK 786 Query: 776 AFCMFATHFHELTAL-ANQIPTVNNLHVTALTTEET--------------LTMLYQVKKG 820 + +F TH+ + L N V N H+ L +E+ +T LYQ+ +G Sbjct: 787 SLTLFVTHYPPVCELEKNYSHQVGNYHMGFLVSEDESKLDPGAAEQVPDFVTFLYQITRG 846 Query: 821 VCDQSFGIHVAELANFPKHVIECAKQKALELE 852 + +S+G++VA+LA+ P +++ A K+ ELE Sbjct: 847 IAARSYGLNVAKLADVPGEILKKAAHKSKELE 878 >5AKB-A nrPDB Length = 800 Score = 663 bits (1711), Expect = 0.0, Method: Composition-based stats. Identities = 183/595 (30%), Positives = 295/595 (49%), Gaps = 34/595 (5%) Query: 264 QVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGS 323 +S+ A++++ + + +T + +D A R L + Q Sbjct: 231 PRGLSAAGALLQYAKCTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAG--GAE 288 Query: 324 QSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRR 383 +LA++L+ TP G R++ +W+ P+ D + ER + A + LQ +LR+ Sbjct: 289 NTLASVLDSTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGAL---QDFTAGLQP-VLRQ 344 Query: 384 FPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDL 443 DL R+ + + A +D R+ QLP + LE V P+ L Sbjct: 345 VGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLE-----------TVDSAPVQAL 393 Query: 444 RSDFSKFQEMIETTLDMDQVENHEFLVK------PSFDPNLSELREIMNDLEKKMQSTLI 497 R +F E + L+ ++ LV+ ++ L E R + + ++ + Sbjct: 394 REKMGEFAE-LRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEV 452 Query: 498 SAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLT 557 GLD +K+ +A GYY +++ + + N+ KN ++ +L Sbjct: 453 RERERTGLD---TLKVGFNAVHGYYIQISRGQSHL--APINYMRRQTLKNAERYIIPELK 507 Query: 558 SLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPV 617 ++ +K + + + +E+ ++ ++E +Q LA+LD +V+ A + Sbjct: 508 EYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAE--RAYTL 565 Query: 618 PYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKST 677 Y P ++K RI RH VE FI N + ++M IITGPNMGGKST Sbjct: 566 NYTSPTFIDKPGIRI--TEGRHPVVEQVLNEPFIANPLNLSPQRRML-IITGPNMGGKST 622 Query: 678 YIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILR 737 Y+RQT +I LMA IG +VP + E+ +D I RVGA D G STFM EM ETA+IL Sbjct: 623 YMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH 682 Query: 738 SATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTV 797 +AT+ SL+++DE+GRGTSTYDG LAWA++E +A KI A +FATH+ ELT L ++ V Sbjct: 683 NATEYSLVLMDEIGRGTSTYDGLSLAWAVAENLANKIKALTLFATHYFELTQLPEKMEGV 742 Query: 798 NNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELE 852 N+H+ AL +T+ ++ V+ G +S+G+ VA LA PK VI+ A+QK ELE Sbjct: 743 ANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELE 797 >5X9W-A nrPDB Length = 816 Score = 663 bits (1711), Expect = 0.0, Method: Composition-based stats. Identities = 184/676 (27%), Positives = 298/676 (44%), Gaps = 54/676 (7%) Query: 186 NLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLL 245 L L ++ E +LP + A + + T F+ + L Sbjct: 162 KLNDELARLQAAEILLPDSKNAPQLQTASGV--------TRLNAWQFAADAGEKLLTEYF 213 Query: 246 KGKKGEQMNSAV-LPEMENQVAVSSLSAVIKFLELLSD--DSNFGQFELTTFDFSQYMKL 302 G Q L E+ V++ + A++ ++ L + + L T SQY+ + Sbjct: 214 ----GCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETD--SQYIGM 267 Query: 303 DIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNL 362 D A R L + Q T +L ++L+ C T G RL+ W+ PL ++ I R Sbjct: 268 DAATRRNLEITQTLSGKKT--PTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEA 325 Query: 363 VEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALE 422 V A E Q L+ D+ R+A + A +D L + +L + L Sbjct: 326 VTALESQYEPLQC----HLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQI--DLS 379 Query: 423 KHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELR 482 + L AVF P T ++ K M E ++ + ++ F P L ELR Sbjct: 380 ATGSSLLETLKAVF--PETLPVAETLKAAVMPEPSVWLKD----GNVINHGFHPELDELR 433 Query: 483 EIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTV 542 I N ++ + GL +K++ + G+Y ++ + + + ++ Sbjct: 434 RIQNHGDEFLLDLEAKERERTGLS---TLKVEFNRVHGFYIELSKTQAE--QAPADYQRR 488 Query: 543 DIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQ----DAIVKEIVNIS--SGYVEPMQTLN 596 KN +F +L + ++ + + + D ++K + Sbjct: 489 QTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAAL 548 Query: 597 DVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVY 656 DVL+ A A N +VRP + + ++ RH VE Q F N Sbjct: 549 DVLSTFSA---LAKERN-----FVRPEFADYPV--VHIENGRHPVVEQQVR-HFTANHTD 597 Query: 657 FEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGD 716 + K ++TGPNMGGKSTY+RQ +IVL+A GCFVP ++A + VD I R+GA D Sbjct: 598 LDH-KHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRIGASD 656 Query: 717 SQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGA 776 STFM EM ETA IL AT+ S++++DE+GRGTST+DG LA AI+E++ K + Sbjct: 657 DLASNRSTFMVEMSETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKS 716 Query: 777 FCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANF 836 F +FATH+ ELT L N+H++AL + L+Q++ G +S+GI VA+LA Sbjct: 717 FSLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGL 776 Query: 837 PKHVIECAKQKALELE 852 P ++ A++ LE Sbjct: 777 PVRALKAAQKHLNGLE 792 >1NNE-A nrPDB Length = 765 Score = 639 bits (1647), Expect = 0.0, Method: Composition-based stats. Identities = 187/593 (31%), Positives = 299/593 (50%), Gaps = 51/593 (8%) Query: 259 PEMENQVAVS-SLSAVIKFLELLSDDSNFGQFELTTFDF---SQYMKLDIAAVRALNLFQ 314 PE E +A+ + A++ + + + G L F F +M+L A +RAL +F Sbjct: 209 PEGEGPLALRRARGALLAY----AQRTQGGALSLQPFRFYDPGAFMRLPEATLRALEVF- 263 Query: 315 GSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQ 374 E G +L ++L++ +T G+RL+ W++ PL+D+ +E RL+ VE FV + LR+ Sbjct: 264 ---EPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARLDRVEGFVREGALRE 320 Query: 375 TLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLA 434 ++ LL R DL RLA + + A+ +D L + + LP + L + G Sbjct: 321 GVRR-LLYRLADLERLATRLELGRASPKDLGALRRSLQILPELRALLGEEVG-------- 371 Query: 435 VFVTPLTDLRSDFSKFQEMIETTL--DMDQVENHEFLVKPSFDPNLSELREIMNDLEKKM 492 D S +E +E L D + L++ +DP+L LR + Sbjct: 372 ---------LPDLSPLKEELEAALVEDPPLKVSEGGLIREGYDPDLDALRAAHREGVAYF 422 Query: 493 QSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFT 552 G+ +K+ +A FGYY VT + R K + V K+ ++T Sbjct: 423 LELEERERERTGI---PTLKVGYNAVFGYYLEVTRPYYE--RVPKEYRPVQTLKDRQRYT 477 Query: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612 ++ E + + ++ + E+ + E ++ +LA+LD + A V+ Sbjct: 478 LPEMKEKEREVYRLEALIRRREEEVFLEVRERAKRQAEALREAARILAELDVYAALAEVA 537 Query: 613 NGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNM 672 YVRP + R+ ++A RH VE + E F+PND+ + +ITGPNM Sbjct: 538 --VRYGYVRP----RFGDRLQIRAGRHPVVERRTE--FVPNDLEMAHE---LVLITGPNM 586 Query: 673 GGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLET 732 GKST++RQT +I L+AQ+G FVP E A + + D I R+GA D G STFM EM E Sbjct: 587 AGKSTFLRQTALIALLAQVGSFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEMEEV 646 Query: 733 ASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALAN 792 A IL+ AT++SL+++DE+GRGTS+ DG +A A++E + + A+ +FATH+ ELTAL Sbjct: 647 ALILKEATENSLVLLDEVGRGTSSLDGVAIATAVAEALHER-RAYTLFATHYFELTALG- 704 Query: 793 QIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAK 845 +P + NLHV A L +QV G +S+G+ VA +A PK V+ A+ Sbjct: 705 -LPRLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARAR 756 >1EWR-A nrPDB Length = 649 Score = 638 bits (1645), Expect = 0.0, Method: Composition-based stats. Identities = 187/593 (31%), Positives = 299/593 (50%), Gaps = 51/593 (8%) Query: 259 PEMENQVAVS-SLSAVIKFLELLSDDSNFGQFELTTFDF---SQYMKLDIAAVRALNLFQ 314 PE E +A+ + A++ + + + G L F F +M+L A +RAL +F Sbjct: 93 PEGEGPLALRRARGALLAY----AQRTQGGALSLQPFRFYDPGAFMRLPEATLRALEVF- 147 Query: 315 GSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQ 374 E G +L ++L++ +T G+RL+ W++ PL+D+ +E RL+ VE FV + LR+ Sbjct: 148 ---EPLRGQDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPLEARLDRVEGFVREGALRE 204 Query: 375 TLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLA 434 ++ LL R DL RLA + + A+ +D L + + LP + L + G Sbjct: 205 GVRR-LLYRLADLERLATRLELGRASPKDLGALRRSLQILPELRALLGEEVG-------- 255 Query: 435 VFVTPLTDLRSDFSKFQEMIETTL--DMDQVENHEFLVKPSFDPNLSELREIMNDLEKKM 492 D S +E +E L D + L++ +DP+L LR + Sbjct: 256 ---------LPDLSPLKEELEAALVEDPPLKVSEGGLIREGYDPDLDALRAAHREGVAYF 306 Query: 493 QSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFT 552 G+ +K+ +A FGYY VT + R K + V K+ ++T Sbjct: 307 LELEERERERTGI---PTLKVGYNAVFGYYLEVTRPYYE--RVPKEYRPVQTLKDRQRYT 361 Query: 553 NSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVS 612 ++ E + + ++ + E+ + E ++ +LA+LD + A V+ Sbjct: 362 LPEMKEKEREVYRLEALIRRREEEVFLEVRERAKRQAEALREAARILAELDVYAALAEVA 421 Query: 613 NGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNM 672 YVRP + R+ ++A RH VE + E F+PND+ + +ITGPNM Sbjct: 422 --VRYGYVRP----RFGDRLQIRAGRHPVVERRTE--FVPNDLEMAHE---LVLITGPNM 470 Query: 673 GGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLET 732 GKST++RQT +I L+AQ+G FVP E A + + D I R+GA D G STFM EM E Sbjct: 471 AGKSTFLRQTALIALLAQVGSFVPAEEAHLPLFDGIYTRIGASDDLAGGKSTFMVEMEEV 530 Query: 733 ASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALAN 792 A IL+ AT++SL+++DE+GRGTS+ DG +A A++E + + A+ +FATH+ ELTAL Sbjct: 531 ALILKEATENSLVLLDEVGRGTSSLDGVAIATAVAEALHER-RAYTLFATHYFELTALG- 588 Query: 793 QIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAK 845 +P + NLHV A L +QV G +S+G+ VA +A PK V+ A+ Sbjct: 589 -LPRLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAMAGLPKEVVARAR 640 >1XDV-A nrPDB Length = 847 Score = 35.9 bits (81), Expect = 0.080, Method: Composition-based stats. Identities = 25/197 (12%), Positives = 68/197 (34%), Gaps = 23/197 (11%) Query: 284 SNFGQFELTTFDFSQYMKLDIAAV-RALNLFQ------GSVEDTTGSQSLAALLNKCKTP 336 F L + ++ + L + + RA+ + + S +L ++ Sbjct: 575 ETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTN- 633 Query: 337 QGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQR 396 + W ++ +++ +EER+ +V +E + + + N + + Sbjct: 634 -----LTLWFEKCIVETENLEERVAVVSRIIE--------ILQVFQELNNFNGVLEVVSA 680 Query: 397 QAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIET 456 ++ YRL Q+P+ + + + + + ++ L + F + T Sbjct: 681 MNSSP--VYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLT 738 Query: 457 TLDMDQVENHEFLVKPS 473 + + N E L + Sbjct: 739 NILKTEEGNPEVLKRHG 755 >5OVF-A nrPDB Length = 490 Score = 35.9 bits (81), Expect = 0.082, Method: Composition-based stats. Identities = 25/197 (12%), Positives = 68/197 (34%), Gaps = 23/197 (11%) Query: 284 SNFGQFELTTFDFSQYMKLDIAAV-RALNLFQ------GSVEDTTGSQSLAALLNKCKTP 336 F L + ++ + L + + RA+ + + S +L ++ Sbjct: 213 ETFDLLTLHPIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTN- 271 Query: 337 QGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQR 396 + W ++ +++ +EER+ +V +E + + + N + + Sbjct: 272 -----LTLWFEKCIVETENLEERVAVVSRIIE--------ILQVFQELNNFNGVLEVVSA 318 Query: 397 QAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIET 456 ++ YRL Q+P+ + + + + + ++ L + F + T Sbjct: 319 MNSSP--VYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLT 376 Query: 457 TLDMDQVENHEFLVKPS 473 + + N E L + Sbjct: 377 NILKTEEGNPEVLKRHG 393 >3QB5-K nrPDB Length = 290 Score = 35.5 bits (80), Expect = 0.12, Method: Composition-based stats. Identities = 31/149 (20%), Positives = 52/149 (34%), Gaps = 3/149 (2%) Query: 158 QRQVGVGYVDSIQRKLGLCEFPDN-DQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQI 216 QR+ G S L F D + L+++ ++ + T + ++ Sbjct: 22 QRREGKDVNSSSPVMLAFKSFQQELDARHDKYERLVKLS-RDITVESKRTIFLLHRITSA 80 Query: 217 IQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKF 276 IL K D + I+Q L G+ Q + A+ ++ V S IK Sbjct: 81 PDMEDILTESEIKLDGVRQKIFQVAQEL-SGEDMHQFHRAITTGLQEYVEAVSFQHFIKT 139 Query: 277 LELLSDDSNFGQFELTTFDFSQYMKLDIA 305 L+S D Q TT D + K + Sbjct: 140 RSLISMDEINKQLIFTTEDNGKENKTPSS 168 >4B0S-A nrPDB Length = 506 Score = 34.4 bits (77), Expect = 0.27, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 54/139 (38%), Gaps = 14/139 (10%) Query: 562 EYTKNKTEYEEAQDAIVKE-IVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAP---V 617 + KN T+ + A + ++N S+ + + ++ L V GA Sbjct: 139 QLYKNNTDNKGASYGCHENYLMNRSTPFADIVRHLIPFFVTRQVFCGAGRVGIGADGRGE 198 Query: 618 PYVRPAILEKGQGRIILKAS-RHACVEVQDEIAFIPNDVYFEKDKQMFHIITG-PNMGGK 675 + + + + L+ + + + +DE P + + H+I G NM Sbjct: 199 GFQLSQRADFFEVEVGLETTLKRPIINTRDEPHADP------EKYRRLHVIIGDANMSEI 252 Query: 676 STYIR--QTGVIVLMAQIG 692 +TY++ T +++ M + G Sbjct: 253 ATYLKLGTTALVLAMIEDG 271 >4A2W-A nrPDB Length = 936 Score = 33.2 bits (74), Expect = 0.57, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 884 IQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNE 925 + EF + VK P+TE+ E+++T K ++ + E+IA + NE Sbjct: 571 LTEFFTNVKNGPYTEL-EQHLTAKFQEKEPELIALSKDETNE 611 >4A2Q-A nrPDB Length = 797 Score = 33.2 bits (74), Expect = 0.57, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 884 IQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNE 925 + EF + VK P+TE+ E+++T K ++ + E+IA + NE Sbjct: 571 LTEFFTNVKNGPYTEL-EQHLTAKFQEKEPELIALSKDETNE 611 >4A36-A nrPDB Length = 556 Score = 33.2 bits (74), Expect = 0.59, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 884 IQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNE 925 + EF + VK P+TE+ E+++T K ++ + E+IA + NE Sbjct: 330 LTEFFTNVKNGPYTEL-EQHLTAKFQEKEPELIALSKDETNE 370 >4P9F-A nrPDB Length = 215 Score = 32.1 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 29/177 (16%), Positives = 60/177 (33%), Gaps = 25/177 (14%) Query: 337 QGQRLVNQWIKQPL-MDKNRIEE---RLNLVEAFVEDAELRQTLQEDLLRRFPDLNRL-- 390 G RL+ + + + L M + E RL V A T+ E R+ ++NR+ Sbjct: 25 PGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRY 84 Query: 391 -----AKKFQRQAANLQDCYRLYQGINQL--PNVIQALEKHEGKHQKLLLAVFVTPLTDL 443 A + QD L + + +L +E+ ++ LA++ + Sbjct: 85 ELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPI 144 Query: 444 RSDFSK------------FQEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMNDL 488 + + E I + +EN+ L+ + R + ++ Sbjct: 145 LCEMIEQLWVRMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEI 201 >2UVP-A nrPDB Length = 186 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 5/78 (6%) Query: 26 MPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMN- 84 + E+P +V F+ FY + + LA E+ + ++G + L++++LSK+ Sbjct: 80 LKERPLLSVIDFNASSFYPKNDANLSLATIEMTYQNPMFWHVGKIENEGLKTILLSKIPS 139 Query: 85 ----FESFVKDLLLVRQY 98 FE +D LL++++ Sbjct: 140 FLWLFEELKEDCLLLKEH 157 >4N4N-A nrPDB Length = 546 Score = 30.5 bits (67), Expect = 3.9, Method: Composition-based stats. Identities = 19/140 (13%), Positives = 43/140 (30%), Gaps = 8/140 (5%) Query: 381 LRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPL 440 + PD A K R A ++ Y + P + + +++++ P Sbjct: 2 ISTVPDETYDALKLDRGKATPKETYEALVKRYKDPAHGAGKGTMGDYWEPIAISIYMDPN 61 Query: 441 TDLRSDFSKFQEMIETTLDMDQVENHEFLVKP---SFDPNLSELREIMNDLEKK-----M 492 T + S + + V+ S NL ++R + +D + Sbjct: 62 TFYKPPVSPKEVAERKDCVECHSDETPVWVRAWKRSTHANLDKIRNLKSDDPLYYKKGKL 121 Query: 493 QSTLISAARDLGLDPGKQIK 512 + + L + +K Sbjct: 122 EEVENNLRSMGKLGEKETLK 141 >2V3C-C nrPDB Length = 432 Score = 30.1 bits (66), Expect = 4.0, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 54/121 (44%), Gaps = 17/121 (14%) Query: 818 KKGVCDQSFGIHVAELANFPKHVIECAKQKALELEE-------FQYIGESQGYDIMEPAA 870 + G+ ++F V E+ + ++ + + L ++IG +G D +EP Sbjct: 225 QAGIQAKAFKEAVGEIGSIIVTKLDGSAKGGGALSAVAETKAPIKFIGIGEGIDDLEPFD 284 Query: 871 KKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNEIISRI 930 K ++ R G ++ L K + M E +EE+I + I + +NE+++++ Sbjct: 285 PKKFISRLLGMGDLESLLEKAEDM-VDEKTEESI---------DAIMRGKFTLNELMTQL 334 Query: 931 K 931 + Sbjct: 335 E 335 >6CON-A nrPDB Length = 305 Score = 29.8 bits (65), Expect = 6.0, Method: Composition-based stats. Identities = 15/127 (11%), Positives = 35/127 (27%), Gaps = 11/127 (8%) Query: 399 ANLQDCYRLYQGINQLPN------VIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQE 452 A D L G+ + L + L +P + Sbjct: 110 AREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIA 169 Query: 453 MIETTLD-----MDQVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDP 507 M LD ++ ++H DP +L + + +++ + P Sbjct: 170 MPALRLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVP 229 Query: 508 GKQIKLD 514 + + ++ Sbjct: 230 PQALLVN 236 >4FIN-A nrPDB Length = 555 Score = 29.8 bits (65), Expect = 6.4, Method: Composition-based stats. Identities = 24/136 (17%), Positives = 45/136 (33%), Gaps = 5/136 (3%) Query: 548 GVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVS 607 +S L ++ + ++ + +I KE+ + G LA+ + + S Sbjct: 240 WEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWVRQGTKGRQSKGKARLARFEELNS 299 Query: 608 FAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHII 667 + P G + + R + + + +D+ F K I Sbjct: 300 TEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYGDR-----LLIDDLSFSIPKGAIVGI 354 Query: 668 TGPNMGGKSTYIRQTG 683 GPN GKST R Sbjct: 355 IGPNGAGKSTLFRMIS 370 >4B3J-A nrPDB Length = 736 Score = 29.4 bits (64), Expect = 8.3, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 19/32 (59%) Query: 681 QTGVIVLMAQIGCFVPCESAEVSIVDCILARV 712 Q + ++AQ F P ++ E+ +VD ++A V Sbjct: 179 QNAFVSVLAQGTRFKPAKAKEIGLVDELVATV 210 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.124 0.307 Lambda K H 0.267 0.0382 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,833,457 Number of Sequences: 36641 Number of extensions: 1137071 Number of successful extensions: 3709 Number of sequences better than 10.0: 23 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 3604 Number of HSP's gapped (non-prelim): 64 length of query: 934 length of database: 10,336,785 effective HSP length: 106 effective length of query: 828 effective length of database: 6,452,839 effective search space: 5342950692 effective search space used: 5342950692 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 64 (29.4 bits)