BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P43235 (329 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 7PCK-A nrPDB 655 0.0 5JA7-A nrPDB 462 e-131 6BKI-A nrPDB 397 e-111 2C0Y-A nrPDB 359 1e-99 1CJL-A nrPDB 327 4e-90 3HWN-A nrPDB 286 7e-78 3OF9-A nrPDB 270 9e-73 3KFQ-A nrPDB 270 9e-73 2O6X-A nrPDB 270 9e-73 3QT4-A nrPDB 269 1e-72 4BS5-A nrPDB 264 4e-71 4P6E-A nrPDB 259 1e-69 3QJ3-A nrPDB 256 9e-69 2VHS-A nrPDB 254 4e-68 1ICF-A nrPDB 220 8e-58 6CZS-A nrPDB 219 1e-57 3F75-A nrPDB 209 1e-54 1CQD-A nrPDB 206 1e-53 1NB3-A nrPDB 205 2e-53 1IWD-A nrPDB 199 1e-51 5EF4-A nrPDB 199 2e-51 1S4V-A nrPDB 198 3e-51 5A24-A nrPDB 192 1e-49 2FO5-A nrPDB 190 8e-49 4YYR-A nrPDB 184 3e-47 3P5W-A nrPDB 184 6e-47 2PNS-A nrPDB 182 1e-46 1O0E-A nrPDB 182 2e-46 1PCI-A nrPDB 182 3e-46 4YYW-A nrPDB 181 4e-46 3BCN-A nrPDB 179 2e-45 1YAL-A nrPDB 178 2e-45 4QRX-A nrPDB 178 3e-45 4YYQ-A nrPDB 175 3e-44 1AEC-A nrPDB 174 4e-44 3U8E-A nrPDB 172 2e-43 2BDZ-A nrPDB 172 2e-43 2ACT-A nrPDB 171 4e-43 6EXO-A nrPDB 167 6e-42 2B1M-A nrPDB 165 3e-41 4PI3-A nrPDB 161 4e-40 6MIS-A nrPDB 159 1e-39 1PPO-A nrPDB 157 5e-39 2CIO-A nrPDB 157 7e-39 1GEC-E nrPDB 155 3e-38 3IOQ-A nrPDB 152 2e-37 3BPM-A nrPDB 150 7e-37 3BPF-A nrPDB 149 2e-36 5I4H-A nrPDB 146 2e-35 1M6D-A nrPDB 143 1e-34 5JT8-A nrPDB 129 1e-30 1XKG-A nrPDB 129 2e-30 5I4H-B nrPDB 126 2e-29 5VCN-A nrPDB 120 6e-28 5VPK-A nrPDB 119 2e-27 3PDF-A nrPDB 115 3e-26 1JQP-A nrPDB 111 3e-25 1CPJ-A nrPDB 92 4e-19 1MIR-A nrPDB 91 7e-19 3PBH-A nrPDB 87 1e-17 3CBK-A nrPDB 83 2e-16 1EF7-A nrPDB 82 4e-16 1DEU-A nrPDB 82 4e-16 4I05-A nrPDB 80 1e-15 5OGQ-A nrPDB 78 6e-15 4HWY-A nrPDB 77 8e-15 4I04-A nrPDB 77 1e-14 4OEL-A nrPDB 76 2e-14 4CDF-B nrPDB 73 2e-13 2DCB-A nrPDB 66 2e-11 1CSB-B nrPDB 62 5e-10 1SP4-B nrPDB 55 4e-08 4OEM-B nrPDB 52 3e-07 3CH2-X nrPDB 52 4e-07 5FPW-A nrPDB 50 2e-06 4D59-A nrPDB 46 3e-05 4CI7-A nrPDB 45 3e-05 2L95-A nrPDB 44 1e-04 3OIS-A nrPDB 37 0.013 5WDK-A nrPDB 35 0.054 4K7C-A nrPDB 33 0.18 2CB5-A nrPDB 32 0.47 1URT-A nrPDB 30 1.3 3SKS-A nrPDB 28 6.7 1A6R-A nrPDB 27 8.7 >7PCK-A nrPDB Length = 314 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/314 (100%), Positives = 314/314 (100%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM Sbjct: 1 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 60 Query: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ Sbjct: 61 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 120 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 195 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI Sbjct: 121 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 180 Query: 196 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTS 255 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTS Sbjct: 181 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTS 240 Query: 256 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 315 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN Sbjct: 241 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 300 Query: 316 NACGIANLASFPKM 329 NACGIANLASFPKM Sbjct: 301 NACGIANLASFPKM 314 >5JA7-A nrPDB Length = 223 Score = 462 bits (1190), Expect = e-131, Method: Compositional matrix adjust. Identities = 222/223 (99%), Positives = 222/223 (99%) Query: 107 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQN 166 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGS WAFSSVGALEGQLKKKTGKLLNLSPQN Sbjct: 1 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQN 60 Query: 167 LVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE 226 LVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE Sbjct: 61 LVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE 120 Query: 227 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ 286 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ Sbjct: 121 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ 180 Query: 287 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM Sbjct: 181 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >6BKI-A nrPDB Length = 215 Score = 397 bits (1021), Expect = e-111, Method: Compositional matrix adjust. Identities = 185/214 (86%), Positives = 199/214 (92%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 PDS+DYRKKGYVTPVKNQGQCGSCWAFSS GALEGQLKKKTGKLL LSPQNLVDCV+EN Sbjct: 2 PDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENY 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GCGGGYMT AFQYVQ+N GIDSEDAYPYVGQ+ESCMYN KAAKCRGYREIP GNEKAL Sbjct: 62 GCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGNEKAL 121 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 KRAVARVGP+SV+IDASL SFQFYS+GVYYDE+C+ DN+NHAVL VGYG QKG+KHWIIK Sbjct: 122 KRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIK 181 Query: 296 NSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 NSWGE+WGNKGY L+ARNKNNACGI N+ASFPKM Sbjct: 182 NSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >2C0Y-A nrPDB Length = 315 Score = 359 bits (921), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 177/317 (55%), Positives = 223/317 (70%), Gaps = 6/317 (1%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 L+ + LD HW LWKKT+ KQY K +E RRLIWEKNLK++ +HNLE S+G+H+Y+L M Sbjct: 2 LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGM 61 Query: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135 NHLGDMTSEEV+ M+ L+VP R + Y PDSVD+R+KG VT VK QG Sbjct: 62 NHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGS 119 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---NDGCGGGYMTNAFQYVQKN 192 CG+ WAFS+VGALE QLK KTGKL++LS QNLVDC +E N GC GG+MT AFQY+ N Sbjct: 120 CGAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 179 Query: 193 RGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDAS 252 +GIDS+ +YPY ++ C Y+ +AA C Y E+P G E LK AVA GPVSV +DA Sbjct: 180 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 239 Query: 253 LTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312 SF Y GVYY+ SC + N+NH VL VGYG G ++W++KNSWG N+G +GYI MAR Sbjct: 240 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 298 Query: 313 NKNNACGIANLASFPKM 329 NK N CGIA+ S+P++ Sbjct: 299 NKGNHCGIASFPSYPEI 315 >1CJL-A nrPDB Length = 312 Score = 327 bits (839), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 165/316 (52%), Positives = 214/316 (67%), Gaps = 15/316 (4%) Query: 22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81 L+ W WK H + Y +E RR +WEKN+K I +HN E G H++ +AMN GDM Sbjct: 4 LEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 62 Query: 82 TSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSC 139 TSEE Q M GL + P + L+ AP SVD+R+KGYVTPVKNQGQCGS Sbjct: 63 TSEEFRQVMNGLQNRKPRKGKVFQEPLFY-----EAPRSVDWREKGYVTPVKNQGQCGSS 117 Query: 140 WAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDS 197 WAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC GG M AFQYVQ N G+DS Sbjct: 118 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDS 177 Query: 198 EDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQ 257 E++YPY EESC YNP A G+ +IP+ EKAL +AVA VGP+SVAIDA SF Sbjct: 178 EESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFL 236 Query: 258 FYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKHWIIKNSWGENWGNKGYILMARN 313 FY +G+Y++ C+S++++H VL VGYG + GNK+W++KNSWGE WG GY+ MA++ Sbjct: 237 FYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKD 296 Query: 314 KNNACGIANLASFPKM 329 + N CGIA+ AS+P + Sbjct: 297 RRNHCGIASAASYPTV 312 >3HWN-A nrPDB Length = 258 Score = 286 bits (733), Expect = 7e-78, Method: Compositional matrix adjust. Identities = 144/264 (54%), Positives = 184/264 (69%), Gaps = 14/264 (5%) Query: 74 AMNHLGDMTSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVK 131 AMN GDMTSEE Q M G + P + L+ AP SVD+R+KGYVTPVK Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFY-----EAPRSVDWREKGYVTPVK 55 Query: 132 NQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYV 189 NQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC GG M AFQYV Sbjct: 56 NQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYV 115 Query: 190 QKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAI 249 Q N G+DSE++YPY EESC YNP A G+ +IP+ EKAL +AVA VGP+SVAI Sbjct: 116 QDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAI 174 Query: 250 DASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK----GNKHWIIKNSWGENWGNK 305 DA SF FY +G+Y++ C+S++++H VL VGYG + NK+W++KNSWGE WG Sbjct: 175 DAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMG 234 Query: 306 GYILMARNKNNACGIANLASFPKM 329 GY+ MA+++ N CGIA+ AS+P + Sbjct: 235 GYVKMAKDRRNHCGIASAASYPTV 258 >3OF9-A nrPDB Length = 221 Score = 270 bits (689), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 129/222 (58%), Positives = 166/222 (74%), Gaps = 7/222 (3%) Query: 114 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE 173 AP SVD+R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 174 --NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGN 231 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-Q 119 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK---- 287 EKAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + Sbjct: 120 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 179 Query: 288 GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 NK+W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 180 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >3KFQ-A nrPDB Length = 221 Score = 270 bits (689), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 127/220 (57%), Positives = 163/220 (74%), Gaps = 6/220 (2%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE-- 173 P SVD+RKKGYVTPVKNQ QCGSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC Sbjct: 2 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEK 233 N GC GG+M AFQYV++N G+DSE++YPYV +E C Y P A+ G+ + G EK Sbjct: 62 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGKEK 121 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN---- 289 AL +AVA VGP+SVA+DA +SFQFY G+Y++ C+S NL+H VL VGYG + N Sbjct: 122 ALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDNS 181 Query: 290 KHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 K+W++KNSWG WG+ GY+ +A++KNN CGIA AS+P + Sbjct: 182 KYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >2O6X-A nrPDB Length = 310 Score = 270 bits (689), Expect = 9e-73, Method: Compositional matrix adjust. Identities = 145/311 (46%), Positives = 188/311 (60%), Gaps = 14/311 (4%) Query: 23 DTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMT 82 D W WK+ + K+YN D+ RR IWEKN+K+I HNL LG+ TY L +N DMT Sbjct: 2 DDLWHQWKRMYNKEYNG-ADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 60 Query: 83 SEEVVQKMTGLKVPLSHSRSNDTLY--IP-EWEGRA-PDSVDYRKKGYVTPVKNQGQCGS 138 EE K SR++D L +P E RA PD +D+R+ GYVT VK+QG CGS Sbjct: 61 FEEFKAKYL-----TEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGS 115 Query: 139 CWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGID 196 WAFS+ G +EGQ K ++ S Q LVDC N+GCGGG M NA+QY+ K G++ Sbjct: 116 GWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYL-KQFGLE 174 Query: 197 SEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSF 256 +E +YPY E C YN AK G+ + G+E LK V GP +VA+D + F Sbjct: 175 TESSYPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVE-SDF 233 Query: 257 QFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNN 316 Y G+Y ++C+ +NHAVLAVGYG Q G +WI+KNSWG +WG +GYI M RN+ N Sbjct: 234 MMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGN 293 Query: 317 ACGIANLASFP 327 CGIA+LAS P Sbjct: 294 MCGIASLASLP 304 >3QT4-A nrPDB Length = 329 Score = 269 bits (688), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 138/316 (43%), Positives = 193/316 (61%), Gaps = 9/316 (2%) Query: 18 PEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNH 77 P+ + W +K TH+K Y++ ++EI R+LI++ N+ I+ HN + G TY AMN Sbjct: 19 PKSLFQEQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQ 78 Query: 78 LGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAP--DSVDYRKKGYVTPVKNQGQ 135 GDM+ EE + + K + + L +P + P SVD+R V+ VK+QGQ Sbjct: 79 FGDMSKEEFLAYVNRGKA--QKPKHPENLRMPYVSSKKPLAASVDWRSNA-VSEVKDQGQ 135 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNR 193 CGS W+FS+ GA+EGQL + G+L +LS QNL+DC S N GC GG+M +AF Y+ + Sbjct: 136 CGSSWSFSTTGAVEGQLALQRGRLTSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIH-DY 194 Query: 194 GIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASL 253 GI SE AYPY Q + C ++ + GY ++P G+E +L AV + GPV+VAIDA+ Sbjct: 195 GIMSESAYPYEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDAT- 253 Query: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313 QFYS G++YD++CN +LNH VL VGYG G +WI+KNSWG WG GY RN Sbjct: 254 DELQFYSGGLFYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGYWRQVRN 313 Query: 314 KNNACGIANLASFPKM 329 N CGIA AS+P + Sbjct: 314 YGNNCGIATAASYPAL 329 >4BS5-A nrPDB Length = 225 Score = 264 bits (674), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 130/218 (59%), Positives = 161/218 (73%), Gaps = 5/218 (2%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE-- 173 PD+VD+R+KG VT VK QG CG+CWAFS+VGALEGQLK KTGKL++LS QNLVDC +E Sbjct: 9 PDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEK 68 Query: 174 --NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGN 231 N GCGGGYMT AFQY+ N GI+++ +YPY +E C YN +AA C Y ++P G+ Sbjct: 69 YGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGD 128 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E ALK AVA GPVSV IDAS +SF FY GVY D SC + N+NH VL VGYG G + Sbjct: 129 EDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSC-TGNVNHGVLVVGYGTLDGKDY 187 Query: 292 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 W++KNSWG N+G++GYI MARN N CGIA+ S+P++ Sbjct: 188 WLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >4P6E-A nrPDB Length = 230 Score = 259 bits (662), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 126/217 (58%), Positives = 157/217 (72%), Gaps = 4/217 (1%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE-- 173 PDSVD+R+KG VT VK QG CG+CWAFS+VGALE QLK KTGKL++LS QNLVDC +E Sbjct: 8 PDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKY 67 Query: 174 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N GC GG+MT AFQY+ N+GIDS+ +YPY ++ C Y+ +AA C Y E+P G E Sbjct: 68 GNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE 127 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 LK AVA GPVSV +DA SF Y GVYY+ SC + N+NH VL VGYG G ++W Sbjct: 128 DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYW 186 Query: 293 IIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 ++KNSWG N+G +GYI MARNK N CGIA+ S+P++ Sbjct: 187 LVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >3QJ3-A nrPDB Length = 331 Score = 256 bits (654), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 138/319 (43%), Positives = 185/319 (57%), Gaps = 8/319 (2%) Query: 18 PEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNH 77 P + WE +K T+ + Y N +E R+ I++K L+ HN + G+ +Y L +N Sbjct: 14 PSTFVAEKWENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYTLGVNL 73 Query: 78 LGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEG-----RAPDSVDYRKKGYVTPVKN 132 DMT EE+ GL +P ++ + E G R P S D+R +G V+PVKN Sbjct: 74 FTDMTPEEMKAYTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGMVSPVKN 133 Query: 133 QGQCGSCWAFSSVGALEGQLKKKTGKLLN--LSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190 QG CGS WAFSS GA+E Q+K G + +S Q LVDCV GC GG+M +AF YV Sbjct: 134 QGSCGSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVPNALGCSGGWMNDAFTYVA 193 Query: 191 KNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAID 250 +N GIDSE AYPY + +C Y+P AA+ GY + +E L VA GPV+VA D Sbjct: 194 QNGGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKGPVAVAFD 253 Query: 251 ASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 A F YS GVYY+ +C ++ HAVL VGYG + G +W++KNSWG+ WG GY + Sbjct: 254 AD-DPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWGLDGYFKI 312 Query: 311 ARNKNNACGIANLASFPKM 329 ARN NN CGIA +AS P + Sbjct: 313 ARNANNHCGIAGVASVPTL 331 >2VHS-A nrPDB Length = 217 Score = 254 bits (649), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 128/218 (58%), Positives = 163/218 (74%), Gaps = 4/218 (1%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE- 173 AP SVD+R+KGYVTPVKNQGQCG+ +AFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 174 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPK-QE 119 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG-IQKGNKH 291 KAL +AVA VGP+SVAIDA SF FY +G+Y+ C+S +LNHA+L VGYG I K+ Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKY 179 Query: 292 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 180 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >1ICF-A nrPDB Length = 175 Score = 220 bits (560), Expect = 8e-58, Method: Compositional matrix adjust. Identities = 106/174 (60%), Positives = 133/174 (76%), Gaps = 3/174 (1%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE- 173 AP SVD+R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 174 -NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 119 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ 286 KAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFE 173 >6CZS-A nrPDB Length = 335 Score = 219 bits (558), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 136/333 (40%), Positives = 187/333 (56%), Gaps = 20/333 (6%) Query: 3 GLKVLLLPVVSFA-LYPEEILDTHWELWKKTHRKQYNNKVDEISRRL-IWEKNLKYISIH 60 G +L +PV A L + H++ W HRK Y+ +E RL + N + I+ H Sbjct: 11 GAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYS--TEEYHHRLQTFASNWRKINAH 68 Query: 61 NLEASLGVHTYELAMNHLGDMTSEEVVQK-MTGLKVPLSHSRSNDTLYIPEWEGRAPDSV 119 N G HT+++A+N DM+ E+ K + S ++SN Y+ G P SV Sbjct: 69 NN----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSN---YL-RGTGPYPPSV 120 Query: 120 DYRKKG-YVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDG 176 D+RKKG +V+PVKNQG CGS W FS+ GALE + TGK+L+L+ Q LVDC + N G Sbjct: 121 DWRKKGNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHG 180 Query: 177 CGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALK 236 C GG + AF+Y+ N+GI ED YPY G++ C + P + I +E+A+ Sbjct: 181 CQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMV 240 Query: 237 RAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNS--DNLNHAVLAVGYGIQKGNKHWII 294 AVA PVS A + + F Y G+Y SC+ D +NHAVLAVGYG + G +WI+ Sbjct: 241 EAVALYNPVSFAFEVT-QDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIV 299 Query: 295 KNSWGENWGNKGYILMARNKNNACGIANLASFP 327 KNSWG WG GY L+ R K N CG+A AS+P Sbjct: 300 KNSWGPQWGMNGYFLIERGK-NMCGLAACASYP 331 >3F75-A nrPDB Length = 224 Score = 209 bits (533), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 112/220 (50%), Positives = 143/220 (65%), Gaps = 9/220 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSE 173 P VD+R +G VTPVK+Q CGSCWAFS+ GALEG KTGKL++LS Q L+DC Sbjct: 8 PAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRAEG 67 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEK 233 N C GG M +AFQYV + GI SEDAYPY+ ++E C K K G++++P +E Sbjct: 68 NQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRRSEA 127 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNK--H 291 A+K A+A+ PVS+AI+A FQFY +GV +D SC +D L+H VL VGYG K +K Sbjct: 128 AMKAALAK-SPVSIAIEADQMPFQFYHEGV-FDASCGTD-LDHGVLLVGYGTDKESKKDF 184 Query: 292 WIIKNSWGENWGNKGYILMARNK--NNACGIANLASFPKM 329 WI+KNSWG WG GY+ MA +K CG+ ASFP M Sbjct: 185 WIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >1CQD-A nrPDB Length = 221 Score = 206 bits (524), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 105/215 (48%), Positives = 135/215 (62%), Gaps = 6/215 (2%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 PDS+D+R+ G V PVKNQG CGSCWAFS+V A+EG + TG L++LS Q LVDC + N Sbjct: 4 PDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTTANH 63 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GG+M AFQ++ N GI+SE+ YPY GQ+ C Y +P NE++L Sbjct: 64 GCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHNEQSL 123 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 ++AVA PVSV +DA+ FQ Y G++ SCN + NHA+ VGYG + WI+K Sbjct: 124 QKAVANQ-PVSVTMDAAGRDFQLYRSGIFTG-SCNI-SANHALTVVGYGTENDKDFWIVK 180 Query: 296 NSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 NSWG+NWG GYI RN N CGI AS+P Sbjct: 181 NSWGKNWGESGYIRAERNIENPDGKCGITRFASYP 215 >1NB3-A nrPDB Length = 220 Score = 205 bits (521), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 106/217 (48%), Positives = 138/217 (63%), Gaps = 7/217 (3%) Query: 116 PDSVDYRKKG-YVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS-- 172 P S+D+RKKG +V+PVKNQG CGSCW FS+ GALE + TGK+L+L+ Q LVDC Sbjct: 2 PPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNF 61 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N GC GG + AF+Y++ N+GI ED YPY GQ++ C + P A + I +E Sbjct: 62 NNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDE 121 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCN--SDNLNHAVLAVGYGIQKGNK 290 +A+ AVA PVS A + + F Y KG+Y SC+ D +NHAVLAVGYG + G Sbjct: 122 EAMVEAVALYNPVSFAFEVT-NDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIP 180 Query: 291 HWIIKNSWGENWGNKGYILMARNKNNACGIANLASFP 327 +WI+KNSWG WG GY L+ R K N CG+A AS+P Sbjct: 181 YWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYP 216 >1IWD-A nrPDB Length = 215 Score = 199 bits (507), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 103/215 (47%), Positives = 138/215 (64%), Gaps = 7/215 (3%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P VD+R KG V +KNQ QCGSCWAFS+V A+E K +TG+L++LS Q LVDC + + Sbjct: 2 PSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDTASH 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GG+M NAFQY+ N GID++ YPY + SC + G++ + NE AL Sbjct: 62 GCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCKPYRL-RVVSINGFQRVTRNNESAL 120 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 + AVA PVSV ++A+ FQ YS G++ C + NH V+ VGYG Q G +WI++ Sbjct: 121 QSAVASQ-PVSVTVEAAGAPFQHYSSGIFTGP-CGTAQ-NHGVVIVGYGTQSGKNYWIVR 177 Query: 296 NSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 NSWG+NWGN+GYI M RN ++ CGIA L S+P Sbjct: 178 NSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYP 212 >5EF4-A nrPDB Length = 385 Score = 199 bits (505), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 126/309 (40%), Positives = 170/309 (55%), Gaps = 20/309 (6%) Query: 34 RKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGL 93 R+Q+N ++ R +++ N++ I E++ Y+L +N DMT+ E V Sbjct: 43 REQHNIEMRSPERFNVFKYNVRRIH----ESNKMDKPYKLKVNEFADMTNLEFVNTYANS 98 Query: 94 KV----------PLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFS 143 K+ P S + +I + PD VD+R+K VT VK QG CGSCWAF+ Sbjct: 99 KISHFQALRGSAPGSIDTDPNKDFIYANVTKIPDKVDWREKNAVTDVKGQGGCGSCWAFA 158 Query: 144 SVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPY 203 +V ALEG +TGKL+ S Q LVDC N GC GG M AF YV K+ GI E +YPY Sbjct: 159 AVVALEGINAIRTGKLVKFSEQQLVDCDMTNAGCDGGLMEPAFTYVIKHGGIAPEASYPY 218 Query: 204 VGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGV 263 VG+ E+C K G + +P +E+AL++AVA PV+ I S QFYS+GV Sbjct: 219 VGKRETCDKAKIKDVLKIDGRQNVPGLDEEALRKAVAHQ-PVATGIQLSGHGLQFYSEGV 277 Query: 264 YYDESCNSDNLNHAVLAVGYGI-QKGNKHWIIKNSWGENWGNKGYILMAR--NKNNACGI 320 Y + C ++ NH V VGYG +KG K W +KNSWG WG KGYI + R K CG+ Sbjct: 278 YTGD-CGTEP-NHGVGIVGYGENEKGIKFWTVKNSWGPTWGEKGYIHLQRGARKEGLCGV 335 Query: 321 ANLASFPKM 329 A +SFP M Sbjct: 336 AMHSSFPIM 344 >1S4V-A nrPDB Length = 229 Score = 198 bits (503), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 110/218 (50%), Positives = 142/218 (65%), Gaps = 9/218 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC-VSEN 174 P SVD+RKKG VT VK+QGQCGSCWAFS++ A+EG + KT KL++LS Q LVDC +N Sbjct: 3 PASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQN 62 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKAAKCRGYREIPEGNEK 233 GC GG M AF+++++ GI +E YPY + +C + A G+ +PE +E Sbjct: 63 QGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPENDEN 122 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ-KGNKHW 292 AL +AVA PVSVAIDA + FQFYS+GV+ SC ++ L+H V VGYG G K+W Sbjct: 123 ALLKAVANQ-PVSVAIDAGGSDFQFYSEGVFTG-SCGTE-LDHGVAIVGYGTTIDGTKYW 179 Query: 293 IIKNSWGENWGNKGYILMAR---NKNNACGIANLASFP 327 +KNSWG WG KGYI M R +K CGIA AS+P Sbjct: 180 TVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYP 217 >5A24-A nrPDB Length = 222 Score = 192 bits (489), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 114/223 (51%), Positives = 142/223 (63%), Gaps = 13/223 (5%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC-VSEN 174 P +VD+R G VTPVKNQ QCG CWAFS+V A+EG + KTG L +LS + +VDC + N Sbjct: 2 PAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNGN 61 Query: 175 D-GCGGGYMTNAFQYVQKNRGIDSEDAYPYV---GQEESCMYNPTGKAAKCRGYREIPEG 230 D GC GG AFQYV N+GID+E YPY G +C + AA GY+++P Sbjct: 62 DKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPAN 121 Query: 231 NEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ--KG 288 NE+AL++A A P+SVAIDAS SFQ YS G+ Y CN+ NL+HAV VGYG G Sbjct: 122 NEQALQQAAATQ-PISVAIDASDPSFQSYSSGI-YSGPCNT-NLDHAVTVVGYGTDPNSG 178 Query: 289 NKHWIIKNSWGENWGNKGYILMARNKN---NACGIANLASFPK 328 N +WI+KNSWG +WG +GYI M N CGIA AS+P Sbjct: 179 NSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >2FO5-A nrPDB Length = 262 Score = 190 bits (482), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 101/221 (45%), Positives = 146/221 (66%), Gaps = 12/221 (5%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC-VSEN 174 P SVD+R+KG VT VK+QG+CGSCWAFS+V ++EG +TG L++LS Q L+DC ++N Sbjct: 5 PPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTADN 64 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGK----AAKCRGYREIPEG 230 DGC GG M NAF+Y++ N G+ +E AYPY +C + G++++P Sbjct: 65 DGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDVPAN 124 Query: 231 NEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI-QKGN 289 +E+ L RAVA PVSVA++AS +F FYS+GV+ E C ++ L+H V VGYG+ + G Sbjct: 125 SEEDLARAVANQ-PVSVAVEASGKAFMFYSEGVFTGE-CGTE-LDHGVAVVGYGVAEDGK 181 Query: 290 KHWIIKNSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 +W +KNSWG +WG +GYI + ++ + CGIA AS+P Sbjct: 182 AYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYP 222 >4YYR-A nrPDB Length = 222 Score = 184 bits (468), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 98/218 (44%), Positives = 137/218 (62%), Gaps = 9/218 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--E 173 P++VD+R +G V P++NQG+CGSCWAFS V +EG K T +L +LS Q LVDC + + Sbjct: 2 PETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATSYK 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGK-AAKCRGYREIPEGNE 232 N GC GG+MT A+ Y+ KN GI S+ YPY ++ C + + A Y +P NE Sbjct: 62 NLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRNNE 121 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 ALK AVA PVSV I+A +F+ Y GV+ SC + L+HAV+A+GYG + +W Sbjct: 122 NALKNAVAN-QPVSVTIEAGGRAFELYKSGVFVG-SCGT-KLDHAVVAIGYGSENDVDYW 178 Query: 293 IIKNSWGENWGNKGYILMARN---KNNACGIANLASFP 327 +++NSWG NWG +GYI + RN CGIA +++P Sbjct: 179 LVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYP 216 >3P5W-A nrPDB Length = 220 Score = 184 bits (466), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 100/217 (46%), Positives = 134/217 (61%), Gaps = 8/217 (3%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSE 173 PD VD+R G V +K+QGQCGSCWAFS++ A+EG K TG L++LS Q LVDC Sbjct: 2 PDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQN 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYREIPEGNE 232 GC GG+MT+ FQ++ N GI++E YPY +E C + K Y +P NE Sbjct: 62 TRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYNNE 121 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 AL+ AVA PVSVA++A+ +FQ YS G+ + C + ++HAV VGYG + G +W Sbjct: 122 WALQTAVAYQ-PVSVALEAAGYNFQHYSSGI-FTGPCGT-AVDHAVTIVGYGTEGGIDYW 178 Query: 293 IIKNSWGENWGNKGYILMARNKNNA--CGIANLASFP 327 I+KNSWG WG +GY+ + RN CGIA AS+P Sbjct: 179 IVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYP 215 >2PNS-A nrPDB Length = 208 Score = 182 bits (463), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 101/213 (47%), Positives = 129/213 (60%), Gaps = 10/213 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P+ +D+RKKG VTPVKNQG+CGSCWAFS+V +E + +TG L++LS Q LVDC +N Sbjct: 2 PEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNKKNH 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GG A+QY+ N GID+E YPY + C K + GY+ +P NE AL Sbjct: 62 GCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPC--RAAKKVVRIDGYKGVPHCNENAL 119 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 K+AVA P VAIDAS FQ Y G+ + C + LNH V+ VGY +WI++ Sbjct: 120 KKAVASQ-PSVVAIDASSKQFQHYKSGI-FSGPCGT-KLNHGVVIVGY----WKDYWIVR 172 Query: 296 NSWGENWGNKGYILMAR-NKNNACGIANLASFP 327 NSWG WG +GYI M R CGIA L +P Sbjct: 173 NSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYP 205 >1O0E-A nrPDB Length = 208 Score = 182 bits (462), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 103/213 (48%), Positives = 128/213 (60%), Gaps = 10/213 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P+ +D+RKKG VTPVKNQG CGSCWAFS+V +E + +TG L++LS Q LVDC +N Sbjct: 2 PEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCDKKNH 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GG A+QY+ N GID++ YPY + C K GY +P NE AL Sbjct: 62 GCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPC--QAASKVVSIDGYNGVPFCNEXAL 119 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 K+AVA V P +VAIDAS FQ YS G+ + C + LNH V VGY +WI++ Sbjct: 120 KQAVA-VQPSTVAIDASSAQFQQYSSGI-FSGPCGTK-LNHGVTIVGYQA----NYWIVR 172 Query: 296 NSWGENWGNKGYILMAR-NKNNACGIANLASFP 327 NSWG WG KGYI M R CGIA L +P Sbjct: 173 NSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYP 205 >1PCI-A nrPDB Length = 322 Score = 182 bits (461), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 119/309 (38%), Positives = 167/309 (54%), Gaps = 9/309 (2%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 L E L + W H K Y N +++ R I++ NL YI E + ++Y L + Sbjct: 12 LTSTERLIQLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYID----ETNKKNNSYWLGL 67 Query: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135 N D++++E +K G + + +S D +I E P++VD+RKKG VTPV++QG Sbjct: 68 NEFADLSNDEFNEKYVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKKGAVTPVRHQGS 127 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 195 CGSCWAFS+V +EG K +TGKL+ LS Q LVDC + GC GGY A +YV KN GI Sbjct: 128 CGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRSHGCKGGYPPYALEYVAKN-GI 186 Query: 196 DSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLT 254 YPY ++ +C G K G + NE L A+A+ PVSV +++ Sbjct: 187 HLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAK-QPVSVVVESKGR 245 Query: 255 SFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNK 314 FQ Y G++ E ++ AV AVGYG G + +IKNSWG WG KGYI + R Sbjct: 246 PFQLYKGGIF--EGPCGTKVDGAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAP 303 Query: 315 NNACGIANL 323 N+ G+ L Sbjct: 304 GNSPGVCGL 312 >4YYW-A nrPDB Length = 220 Score = 181 bits (459), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 96/218 (44%), Positives = 137/218 (62%), Gaps = 9/218 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--E 173 P++VD+R KG V P+++QG+CGSCW FS +EG +K T L +LS Q L+DC + Sbjct: 2 PETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCAPSYK 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKAAKCRGYREIPEGNE 232 + GC GG+M A+ Y+ K+RGI SE YPY ++ +C T A Y ++P NE Sbjct: 62 DLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPADNE 121 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 ALK+AVA PVSVAIDAS + + YS GV+ SC N +HAV+ VGYG + G +W Sbjct: 122 DALKKAVAN-QPVSVAIDASSAAVKEYSSGVFVG-SCGVAN-DHAVVVVGYGTESGVNYW 178 Query: 293 IIKNSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 +++NSWG WG +GY+ + R+ + CGIA +++P Sbjct: 179 LVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYP 216 >3BCN-A nrPDB Length = 209 Score = 179 bits (454), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 98/213 (46%), Positives = 126/213 (59%), Gaps = 10/213 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P+ VD+R KG V P+KNQG+CGSCWAFS+V +E + +TG L++LS Q LVDC +N Sbjct: 2 PEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKKNH 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GGY A+QY+ N GID+E YPY + C K + G + +P+ NE AL Sbjct: 62 GCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPC--RAAKKVVRIDGCKGVPQCNENAL 119 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 K AVA P VAIDAS FQ Y G++ LNH V+ VGY G +WI++ Sbjct: 120 KNAVASQ-PSVVAIDASSKQFQHYKGGIFTGPC--GTKLNHGVVIVGY----GKDYWIVR 172 Query: 296 NSWGENWGNKGYILMAR-NKNNACGIANLASFP 327 NSWG +WG +GY M R CGIA L +P Sbjct: 173 NSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYP 205 >1YAL-A nrPDB Length = 218 Score = 178 bits (452), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 98/216 (45%), Positives = 127/216 (58%), Gaps = 8/216 (3%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P S+D+R KG VTPVKNQG CGSCWAFS++ +EG K TG LL LS Q LVDC + Sbjct: 2 PQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCDKHSY 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKAAKCRGYREIPEGNEKA 234 GC GGY T + QYV N G+ + YPY ++ C + G K GY+ +P E + Sbjct: 62 GCKGGYQTTSLQYVA-NNGVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCETS 120 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 A+A P+SV ++A FQ Y GV +D C + L+HAV AVGYG G + II Sbjct: 121 FLGALANQ-PLSVLVEAGGKPFQLYKSGV-FDGPCGT-KLDHAVTAVGYGTSDGKNYIII 177 Query: 295 KNSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 KNSWG NWG KGY+ + R N+ CG+ + +P Sbjct: 178 KNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYP 213 >4QRX-A nrPDB Length = 363 Score = 178 bits (451), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 121/317 (38%), Positives = 168/317 (52%), Gaps = 28/317 (8%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 L E L +E W H K Y N ++I R I++ NLKYI E + ++Y L + Sbjct: 56 LTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYID----ETNKKNNSYWLGL 111 Query: 76 NHLGDMTSEEVVQKMTG------LKVPLSHSR--SNDTLYIPEWEGRAPDSVDYRKKGYV 127 N DM+++E +K TG LS+ ++ + IPE+ VD+R+KG V Sbjct: 112 NVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEY-------VDWRQKGAV 164 Query: 128 TPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQ 187 TPVKNQG CGS WAFS+V +E +K +TG L S Q L+DC + GC GGY +A Q Sbjct: 165 TPVKNQGSCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQ 224 Query: 188 YVQKNRGIDSEDAYPYVGQEESCMYNPTGK-AAKCRGYREIPEGNEKALKRAVARVGPVS 246 V + GI + YPY G + C G AAK G R++ NE AL ++A PVS Sbjct: 225 LVAQ-YGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQ-PVS 282 Query: 247 VAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKG 306 V ++A+ FQ Y G++ N ++HAV AVGYG + +I+NSWG WG G Sbjct: 283 VVLEAAGKDFQLYRGGIFVGPCGNK--VDHAVAAVGYGPN----YILIRNSWGTGWGENG 336 Query: 307 YILMARNKNNACGIANL 323 YI + R N+ G+ L Sbjct: 337 YIRIKRGTGNSYGVCGL 353 >4YYQ-A nrPDB Length = 217 Score = 175 bits (443), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 103/219 (47%), Positives = 142/219 (64%), Gaps = 13/219 (5%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--E 173 P++VD+R KG V P++NQGQCGSCWAFS+V A+E K TG+LL+LS Q L+DC + Sbjct: 2 PETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCAQSYK 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKA--AKCRGYREIPEGN 231 N GC GG++ AF+Y+ +NRGI S+ YPY G + C TG A A Y+ +P N Sbjct: 62 NLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCR---TGLASIATIDSYQYVPSNN 118 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E ALK AVA PVSVA++A+ +FQ Y GV + SC ++HAV+ +GYG G + Sbjct: 119 ENALKNAVANQ-PVSVAVEAAGRAFQLYKSGV-FTGSCGVA-IDHAVVLIGYGKYNGVDY 175 Query: 292 WIIKNSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 W+++NSWG NWG +GY+ + RN + CG+A L +P Sbjct: 176 WLLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYP 214 >1AEC-A nrPDB Length = 218 Score = 174 bits (442), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 93/217 (42%), Positives = 131/217 (60%), Gaps = 8/217 (3%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSE 173 P VD+R G V +K+QG+CG CWAFS++ +EG K TG L++LS Q L+DC Sbjct: 2 PSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQN 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYREIPEGNE 232 GC GGY+T+ FQ++ N GI++E+ YPY Q+ C + K Y +P NE Sbjct: 62 TRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNNE 121 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 AL+ AV PVSVA+DA+ +F+ YS G+ + C + ++HAV VGYG + G +W Sbjct: 122 WALQTAVTYQ-PVSVALDAAGDAFKQYSSGI-FTGPCGT-AIDHAVTIVGYGTEGGIDYW 178 Query: 293 IIKNSWGENWGNKGYILMARNKNNA--CGIANLASFP 327 I+KNSW WG +GY+ + RN A CGIA + S+P Sbjct: 179 IVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYP 215 >3U8E-A nrPDB Length = 222 Score = 172 bits (436), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 100/221 (45%), Positives = 131/221 (59%), Gaps = 10/221 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP S+D+RKKG VT VK+QG CG CWAF + GA+EG TG+L+++S Q +VDC + Sbjct: 1 APASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDTXX 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GG +AF++V N GI S+ YPY G + +C N AA+ GY +P + A Sbjct: 61 XXXXGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLNKP-IAARIDGYTNVPN-SSSA 118 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYS-KGVYYDESCNSD--NLNHAVLAVGYGIQKGN-K 290 L AVA+ PVSV I S TSFQ Y+ G++ SC+ D ++H VL VGYG N Sbjct: 119 LLDAVAKQ-PVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNAD 177 Query: 291 HWIIKNSWGENWGNKGYILMARNKN---NACGIANLASFPK 328 +WI+KNSWG WG GYIL+ RN N C I S+P Sbjct: 178 YWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYPT 218 >2BDZ-A nrPDB Length = 214 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 96/216 (44%), Positives = 128/216 (59%), Gaps = 12/216 (5%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P+S+D+R+KG VTPVKNQ CGSCWAFS+V +EG K TG+L++LS Q L+DC + Sbjct: 2 PESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCERRSH 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKAAKCRGYREIPEGNEKA 234 GC GGY T + QYV N G+ +E YPY ++ C + G GY+ +P +E + Sbjct: 62 GCDGGYQTTSLQYVVDN-GVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDEIS 120 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L +A+A PVSV D+ FQFY G+Y E N +HAV AVGY G + ++ Sbjct: 121 LIQAIANQ-PVSVVTDSRGRGFQFYKGGIY--EGPCGTNTDHAVTAVGY----GKTYLLL 173 Query: 295 KNSWGENWGNKGYILMAR---NKNNACGIANLASFP 327 KNSWG NWG KGYI + R CG+ + FP Sbjct: 174 KNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFP 209 >2ACT-A nrPDB Length = 220 Score = 171 bits (433), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 89/217 (41%), Positives = 132/217 (60%), Gaps = 8/217 (3%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSE 173 P VD+R G V +K+QG+CG CWAFS++ +EG K +G L++LS Q L+DC Sbjct: 2 PSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQN 61 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKAAKCRGYREIPEGNE 232 GC GGY+T+ FQ++ + GI++E+ YPY Q+ C + K Y +P NE Sbjct: 62 TRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYENVPYNNE 121 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 AL+ AV PVSVA+DA+ +F+ Y+ G+ + C + ++HA++ VGYG + G +W Sbjct: 122 WALQTAVTYQ-PVSVALDAAGDAFKQYASGI-FTGPCGT-AVDHAIVIVGYGTEGGVDYW 178 Query: 293 IIKNSWGENWGNKGYILMARNKNNA--CGIANLASFP 327 I+KNSW WG +GY+ + RN A CGIA + S+P Sbjct: 179 IVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYP 215 >6EXO-A nrPDB Length = 215 Score = 167 bits (423), Expect = 6e-42, Method: Compositional matrix adjust. Identities = 90/206 (43%), Positives = 128/206 (62%), Gaps = 10/206 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP +VD+R+KG VTPVK+QGQCGSCWAFS++G +EGQ + L++LS Q LV C + + Sbjct: 1 APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTID 60 Query: 175 DGCGGGYMTNAFQYVQKNRG--IDSEDAYPYV---GQEESCMYNPTGKAAKCRGYREIPE 229 GCGGG M NAF ++ + G + +E +YPYV G++ C N A + ++P+ Sbjct: 61 FGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQ 120 Query: 230 GNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN 289 +E A+ +A GP+++A+DA TSF Y+ G+ SC S+ L+H VL VGY Sbjct: 121 -DEDAIAAYLAENGPLAIAVDA--TSFMDYNGGIL--TSCTSEQLDHGVLLVGYNDASNP 175 Query: 290 KHWIIKNSWGENWGNKGYILMARNKN 315 +WIIKNSW WG GYI + + N Sbjct: 176 PYWIIKNSWSNMWGEDGYIRIEKGTN 201 >2B1M-A nrPDB Length = 246 Score = 165 bits (417), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 96/223 (43%), Positives = 129/223 (57%), Gaps = 12/223 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP+S D+ KKG +T VK QGQCGS WAFS+ GA+E TG L++LS Q L+DCV E+ Sbjct: 2 APESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDES 61 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGY------REIP 228 +GC G+ +F++V K+ GI SE YPY ++ C N Y E Sbjct: 62 EGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSNEST 121 Query: 229 EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSD-NLNHAVLAVGYGIQK 287 E ++ ++ P+SV+IDA F FYS G+Y +C+S +NH VL VGYG + Sbjct: 122 ESEAESSLQSFVLEQPISVSIDAK--DFHFYSGGIYDGGNCSSPYGINHFVLIVGYGSED 179 Query: 288 GNKHWIIKNSWGENWGNKGYILMARNKNN---ACGIANLASFP 327 G +WI KNSWGE+WG GYI + RN N CG+ AS+P Sbjct: 180 GVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYP 222 >4PI3-A nrPDB Length = 216 Score = 161 bits (408), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 93/206 (45%), Positives = 124/206 (60%), Gaps = 10/206 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP +VD+R +G VT VK+QGQCGSCWAFS++G +E Q L NLS Q LV C + Sbjct: 2 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTD 61 Query: 175 DGCGGGYMTNAFQY-VQKNRG-IDSEDAYPYV---GQEESCMYNPTGKAAKCRGYREIPE 229 GC GG M NAF++ VQ+N G + +ED+YPY G C + A G+ E+P+ Sbjct: 62 SGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQ 121 Query: 230 GNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN 289 +E + +A GPV+VA+DAS S+ Y+ GV SC S+ L+H VL VGY Sbjct: 122 -DEAQIAAWLAVNGPVAVAVDAS--SWMTYTGGVM--TSCVSEQLDHGVLLVGYNDSAAV 176 Query: 290 KHWIIKNSWGENWGNKGYILMARNKN 315 +WIIKNSW WG +GYI +A+ N Sbjct: 177 PYWIIKNSWTTQWGEEGYIRIAKGSN 202 >6MIS-A nrPDB Length = 215 Score = 159 bits (403), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 85/213 (39%), Positives = 130/213 (61%), Gaps = 6/213 (2%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P S+D+R G VT VKNQG+CGSCWAF+S+ +E K K G L++LS Q ++DC + + Sbjct: 2 PQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDC-AVSY 60 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GG++ A+ ++ N+G+ S YPY + +C N +A Y + NE+ + Sbjct: 61 GCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNERNM 120 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI-QKGNKHWII 294 AV+ P++ A+DAS +FQ Y +GV + C + LNHA++ +GYG G K WI+ Sbjct: 121 MYAVSNQ-PIAAALDAS-GNFQHYKRGV-FTGPCGT-RLNHAIVIIGYGQDSSGKKFWIV 176 Query: 295 KNSWGENWGNKGYILMARNKNNACGIANLASFP 327 +NSWG WG GYI +AR+ +++ G+ +A P Sbjct: 177 RNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDP 209 >1PPO-A nrPDB Length = 216 Score = 157 bits (398), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 94/209 (44%), Positives = 123/209 (58%), Gaps = 5/209 (2%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P++VD+RKKG VTPV++QG CGSCWAFS+V +EG K +TGKL+ LS Q LVDC + Sbjct: 2 PENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRSH 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEKA 234 GC GGY A +YV KN GI YPY ++ +C G K G + NE Sbjct: 62 GCKGGYPPYALEYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGN 120 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L A+A+ PVSV +++ FQ Y G++ E ++HAV AVGYG G + +I Sbjct: 121 LLNAIAKQ-PVSVVVESKGRPFQLYKGGIF--EGPCGTKVDHAVTAVGYGKSGGKGYILI 177 Query: 295 KNSWGENWGNKGYILMARNKNNACGIANL 323 KNSWG WG KGYI + R N+ G+ L Sbjct: 178 KNSWGTAWGEKGYIRIKRAPGNSPGVCGL 206 >2CIO-A nrPDB Length = 212 Score = 157 bits (396), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 93/209 (44%), Positives = 122/209 (58%), Gaps = 9/209 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P+ VD+R+KG VTPVKNQG CGSCWAFS+V +EG +K +TG L S Q L+DC + Sbjct: 2 PEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRRSY 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGK-AAKCRGYREIPEGNEKA 234 GC GGY +A Q V + GI + YPY G + C G AAK G R++ NE A Sbjct: 62 GCNGGYPWSALQLVAQ-YGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGA 120 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L ++A PVSV ++A+ FQ Y G++ N ++HAV AVGY G + +I Sbjct: 121 LLYSIANQ-PVSVVLEAAGKDFQLYRGGIFVGPCGN--KVDHAVAAVGY----GPNYILI 173 Query: 295 KNSWGENWGNKGYILMARNKNNACGIANL 323 KNSWG WG GYI + R N+ G+ L Sbjct: 174 KNSWGTGWGENGYIRIKRGTGNSYGVCGL 202 >1GEC-E nrPDB Length = 216 Score = 155 bits (391), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 94/216 (43%), Positives = 130/216 (60%), Gaps = 8/216 (3%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P+SVD+R KG VTPVK+QG C SCWAFS+V +EG K KTG L+ LS Q LVDC ++ Sbjct: 2 PESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCDLQSY 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEKA 234 GC GY + + QYV +N GI YPY+ ++++C N G K G + NE + Sbjct: 62 GCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSNNEGS 120 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L A+A PVSV ++++ FQ Y G+ ++ SC + ++HAV AVGYG G + +I Sbjct: 121 LLNAIAHQ-PVSVVVESAGRDFQNYKGGI-FEGSCGTK-VDHAVTAVGYGKSGGKGYILI 177 Query: 295 KNSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 KNSWG WG GYI + R N+ CG+ + +P Sbjct: 178 KNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYP 213 >3IOQ-A nrPDB Length = 213 Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 97/216 (44%), Positives = 128/216 (59%), Gaps = 12/216 (5%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P S+D+R+KG VTPV+NQG CGSCW FSSV A+EG K TG+LL+LS Q L+DC + Sbjct: 2 PTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCERRSY 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEKA 234 GC GG+ A QYV N GI YPY G + C + G K G +P NE+A Sbjct: 62 GCRGGFPLYALQYV-ANSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRNNEQA 120 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L + +A + PVS+ ++A +FQ Y G++ S ++HAV AVGY GN + +I Sbjct: 121 LIQRIA-IQPVSIVVEAKGRAFQNYRGGIFAGPCGTS--IDHAVAAVGY----GNDYILI 173 Query: 295 KNSWGENWGNKGYILMARNKNN---ACGIANLASFP 327 KNSWG WG GYI + R N ACG+ + + FP Sbjct: 174 KNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFP 209 >3BPM-A nrPDB Length = 243 Score = 150 bits (379), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 91/226 (40%), Positives = 126/226 (55%), Gaps = 20/226 (8%) Query: 118 SVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGC 177 + D+R G VTPVK+Q CGSCWAFSSVG++E Q + L S Q LVDC +N+GC Sbjct: 23 AYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVKNNGC 82 Query: 178 GGGYMTNAFQYVQKNRGIDSEDAYPYVGQ-EESCMYNPTGKAAKCRGYREIPEGNEKALK 236 GGY+TNAF + G+ S+D YPYV E+C + + Y IP + K Sbjct: 83 YGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIP---DDKFK 139 Query: 237 RAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ---------- 286 A+ +GP+S++I AS F FY +G +YD C + NHAV+ VGYG++ Sbjct: 140 EALRYLGPISISIAAS-DDFAFY-RGGFYDGECGA-APNHAVILVGYGMKDIYNEDTGRM 196 Query: 287 KGNKHWIIKNSWGENWGNKGYILMARNKN---NACGIANLASFPKM 329 + ++IIKNSWG +WG GYI + ++N C I A P + Sbjct: 197 EKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL 242 >3BPF-A nrPDB Length = 241 Score = 149 bits (375), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 87/222 (39%), Positives = 128/222 (57%), Gaps = 20/222 (9%) Query: 120 DYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGG 179 D+R VTPVK+Q CGSCWAFSS+G++E Q + KL+ LS Q LVDC +N GC G Sbjct: 23 DWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYGCNG 82 Query: 180 GYMTNAFQYVQKNRGIDSEDAYPYVGQEES-CMYNPTGKAAKCRGYREIPEGNEKALKRA 238 G + NAF+ + + GI + YPYV + C + + + Y +P + LK A Sbjct: 83 GLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVP---DNKLKEA 139 Query: 239 VARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI--------QKGNK 290 + +GP+S+++ S F FY +G+ +D C D LNHAV+ VG+G+ +KG K Sbjct: 140 LRFLGPISISVAVS-DDFAFYKEGI-FDGEC-GDQLNHAVMLVGFGMKEIVNPLTKKGEK 196 Query: 291 H--WIIKNSWGENWGNKGYILMARNKN---NACGIANLASFP 327 H +IIKNSWG+ WG +G+I + +++ CG+ A P Sbjct: 197 HYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIP 238 >5I4H-A nrPDB Length = 106 Score = 146 bits (368), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 70/103 (67%), Positives = 82/103 (79%), Gaps = 2/103 (1%) Query: 114 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE 173 AP SVD+R+KGYVTPVKNQGQCGS WAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 174 --NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP 103 >1M6D-A nrPDB Length = 214 Score = 143 bits (360), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 89/213 (41%), Positives = 123/213 (57%), Gaps = 6/213 (2%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP D+R KG VT VK+QG CGSCWAFS G +EGQ G LL+LS Q L+DC + Sbjct: 1 APPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMD 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 C GG +NA+ ++ G+++ED Y Y G +SC ++ + E+ + NE+ Sbjct: 61 KACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQ-NEQK 119 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVY--YDESCNSDNLNHAVLAVGYGIQKGNKHW 292 L +A+ GP+SVAI+A QFY G+ C+ ++HAVL VGYG + W Sbjct: 120 LAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPFW 177 Query: 293 IIKNSWGENWGNKGYILMARNKNNACGIANLAS 325 IKNSWG +WG KGY + R + ACG+ +AS Sbjct: 178 AIKNSWGTDWGEKGYYYLHRG-SGACGVNTMAS 209 >5JT8-A nrPDB Length = 333 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 94/313 (30%), Positives = 159/313 (50%), Gaps = 16/313 (5%) Query: 26 WELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEE 85 +E +KK K Y N +E R +++ LK++ HN G+ E A+N DM+ +E Sbjct: 28 FEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHN-----GIDGVEYAINEYSDMSEQE 82 Query: 86 VVQKMTGLKVPLSHSRSNDTLY-IPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSS 144 ++G + ++ + + G P + D+R+K +T ++ QG CGSCWAF++ Sbjct: 83 FSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARLTRIRQQGSCGSCWAFAA 142 Query: 145 VGALEGQLKKKTGKLLNLSPQNLVDCVS-------ENDGCGGGYMTNAFQYVQKNRGIDS 197 G E + + + LS Q LVDC + +GCG GY T AF+Y+ + G+ Sbjct: 143 AGVAESLYSIQKQQSIELSEQELVDCTYNRYDPSYQCNGCGSGYSTEAFKYMIRT-GLVE 201 Query: 198 EDAYPYVGQEESCMYNPTGKAAKCRGYREIP-EGNEKALKRAVARVGPVSVAIDASLTSF 256 E YPY + + C + G+ GY+++ +++ + + + GPV + + S F Sbjct: 202 ERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYHSSDEDVMYTIQQHGPVVIYMHGSNNYF 261 Query: 257 QFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNN 316 + GV + N +HAV+ VG+G +G +WII+NSWG WGN GY + R +N Sbjct: 262 RNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGNGGYGYVERG-HN 320 Query: 317 ACGIANLASFPKM 329 + GI N ++ + Sbjct: 321 SLGINNYVTYATL 333 >1XKG-A nrPDB Length = 312 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 91/294 (30%), Positives = 139/294 (47%), Gaps = 20/294 (6%) Query: 26 WELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEE 85 +E +KK K Y DE + R + +++KY+ +++ G A+NHL D++ +E Sbjct: 8 FEEYKKAFNKSYATFEDEEAARKNFLESVKYV-----QSNGG------AINHLSDLSLDE 56 Query: 86 VVQKMTGLKVPLSHSRSNDTLYIP----EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWA 141 + H ++ L G AP +D R+ VTP++ QG CGS WA Sbjct: 57 FKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSAWA 116 Query: 142 FSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAY 201 FS V A E + L+L+ Q LVDC S++ GC G + +Y+Q N G+ E Y Sbjct: 117 FSGVAATESAYLAYRDQSLDLAEQELVDCASQH-GCHGDTIPRGIEYIQHN-GVVQESYY 174 Query: 202 PYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARV-GPVSVAID-ASLTSFQFY 259 YV +E+SC P + Y +I N ++ A+A+ ++V I L +F+ Y Sbjct: 175 RYVAREQSCR-RPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDLDAFRHY 233 Query: 260 SKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313 HAV VGY +G +WI++NSW NWG+ GY A N Sbjct: 234 DGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAAN 287 >5I4H-B nrPDB Length = 112 Score = 126 bits (316), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 57/111 (51%), Positives = 82/111 (73%), Gaps = 5/111 (4%) Query: 223 GYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVG 282 G+ +IP+ EKAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VG Sbjct: 3 GFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVG 61 Query: 283 YGIQK----GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 YG + NK+W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 62 YGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >5VCN-A nrPDB Length = 222 Score = 120 bits (302), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 73/203 (35%), Positives = 103/203 (50%), Gaps = 5/203 (2%) Query: 113 GRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS 172 G AP +D R+ VTP++ QG CGSCWAFS V A E + L+L+ Q LVDC S Sbjct: 8 GNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCAS 67 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 ++ GC G + +Y+Q N G+ E Y YV +E+SC P + Y +I N Sbjct: 68 QH-GCHGDTIPRGIEYIQHN-GVVQESYYRYVAREQSCR-RPNAQRFGISNYCQIYPPNA 124 Query: 233 KALKRAVARV-GPVSVAIDA-SLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNK 290 ++ A+A+ ++V I L +F+ Y HAV VGY +G Sbjct: 125 NKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVD 184 Query: 291 HWIIKNSWGENWGNKGYILMARN 313 +WI++NSW NWG+ GY A N Sbjct: 185 YWIVRNSWDTNWGDNGYGYFAAN 207 >5VPK-A nrPDB Length = 223 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 69/195 (35%), Positives = 96/195 (49%), Gaps = 5/195 (2%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P +D R VTP++ QG CGSCWAFS V A E L+LS Q LVDC S++ Sbjct: 11 VPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDCASQH 70 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC G + +Y+Q+N G+ E +YPYV +E+ C P + Y +I + K Sbjct: 71 -GCHGDTIPRGIEYIQQN-GVVEERSYPYVAREQQCR-RPNSQHYGISNYCQIYPPDVKQ 127 Query: 235 LKRAVARVGPVSVAIDA--SLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 ++ A+ + I L +FQ Y HAV VGYG +G +W Sbjct: 128 IREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQGVDYW 187 Query: 293 IIKNSWGENWGNKGY 307 I++NSW WG+ GY Sbjct: 188 IVRNSWDTTWGDSGY 202 >3PDF-A nrPDB Length = 441 Score = 115 bits (287), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 94/313 (30%), Positives = 147/313 (46%), Gaps = 34/313 (10%) Query: 31 KTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTY-ELAMNHLGDMT--SEEVV 87 K +++Y+N++ + + +I+ ++ S TY E LGDM S Sbjct: 133 KNSQEKYSNRLYKYDHNFV-------KAINAIQKSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 88 QKMTGLK-VPLSHSRSNDTLYIP-EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSV 145 +K+ K PL+ L++P W+ R +++ V+PV+NQ CGSC++F+S+ Sbjct: 186 RKIPRPKPAPLTAEIQQKILFLPTSWDWRNVHGINF-----VSPVRNQASCGSCYSFASM 240 Query: 146 GALEGQLKKKT--GKLLNLSPQNLVDCVSENDGCGGGY-MTNAFQYVQKNRGIDSEDAYP 202 G LE +++ T + LSPQ +V C GC GG+ A +Y Q + G+ E +P Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQ-DFGLVEEACFP 299 Query: 203 YVGQEESCMYNPTGKAAKCRGYREI----PEGNEKALKRAVARVGPVSVAIDASLTSFQF 258 Y G + C Y + NE +K + GP++VA + F Sbjct: 300 YTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLH 358 Query: 259 YSKGVYY-----DESCNSDNLNHAVLAVGYGIQ--KGNKHWIIKNSWGENWGNKGYILMA 311 Y KG+Y+ D + NHAVL VGYG G +WI+KNSWG WG GY + Sbjct: 359 YKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIR 418 Query: 312 RNKNNACGIANLA 324 R + C I ++A Sbjct: 419 RGTDE-CAIESIA 430 >1JQP-A nrPDB Length = 438 Score = 111 bits (278), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 77/247 (31%), Positives = 116/247 (46%), Gaps = 29/247 (11%) Query: 96 PLSHSRSNDTLYIPE-WEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154 P++ L +PE W+ R + R +V+PV+NQ CGSC++F+S+G LE +++ Sbjct: 194 PITDEIQQQILSLPESWDWR-----NVRGINFVSPVRNQESCGSCYSFASLGMLEARIRI 248 Query: 155 KT--GKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMY 212 T + LSPQ +V C GC GG+ ++ G+ E+ +PY + C Sbjct: 249 LTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPC-- 306 Query: 213 NPTGKAAKCRGYRE--------IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVY 264 K R Y NE +K + + GP++VA + F Y G+Y Sbjct: 307 --KPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVH-DDFLHYHSGIY 363 Query: 265 Y-----DESCNSDNLNHAVLAVGYGIQ--KGNKHWIIKNSWGENWGNKGYILMARNKNNA 317 + D + NHAVL VGYG G +WI+KNSWG WG GY + R + Sbjct: 364 HHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRG-TDE 422 Query: 318 CGIANLA 324 C I ++A Sbjct: 423 CAIESIA 429 >1CPJ-A nrPDB Length = 260 Score = 91.7 bits (226), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 120/258 (46%), Gaps = 52/258 (20%) Query: 116 PDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNL--SPQNLVD 169 P+S D R++ P +++QG CGSCWAF +V A+ ++ T +N+ S ++L+ Sbjct: 8 PESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLT 67 Query: 170 C--VSENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQEESCMYNPTGKAAK 220 C + DGC GGY + A+ + + +G+ S Y PY C ++ G Sbjct: 68 CCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYT--IPPCEHHVNGARPP 124 Query: 221 CRGYREIPEGN---------------------------EKALKRAVARVGPVSVAIDASL 253 C G + P+ N EK + + + GPV A Sbjct: 125 CTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEGAFTV-F 183 Query: 254 TSFQFYSKGVYYDESCNSDNLN-HAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312 + F Y GVY E+ D + HA+ +G+GI+ G +W++ NSW +WG+ G+ + R Sbjct: 184 SDFLTYKSGVYKHEA--GDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGFFKILR 241 Query: 313 NKNNACGIAN--LASFPK 328 +N+ CGI + +A P+ Sbjct: 242 GENH-CGIESEIVAGIPR 258 >1MIR-A nrPDB Length = 322 Score = 90.9 bits (224), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 83/331 (25%), Positives = 144/331 (43%), Gaps = 62/331 (18%) Query: 42 DEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSR 101 D+ S + + + YI+ N G + Y + +++L + + G K+P Sbjct: 2 DKPSFHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG----TVLGGPKLPERVGF 57 Query: 102 SNDTLYIPEWEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTG 157 S D P+S D R++ P +++QG CGS WAF +V A+ ++ T Sbjct: 58 SEDI--------NLPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTN 109 Query: 158 KLLNL--SPQNLVDC--VSENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQ 206 +N+ S ++L+ C + DGC GGY + A+ + + +G+ S Y PY Sbjct: 110 GRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYT-- 166 Query: 207 EESCMYNPTGKAAKCRGYREIPEGN---------------------------EKALKRAV 239 C ++ G C G + P+ N EK + + Sbjct: 167 IPPCEHHVNGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEI 226 Query: 240 ARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWG 299 + GPV A + F Y GVY E+ + HA+ +G+GI+ G +W++ NSW Sbjct: 227 YKNGPVEGAFTV-FSDFLTYKSGVYKHEAGDVMG-GHAIRILGWGIENGVPYWLVANSWN 284 Query: 300 ENWGNKGYILMARNKNNACGIAN--LASFPK 328 +WG+ G+ + R +N+ CGI + +A P+ Sbjct: 285 ADWGDNGFFKILRGENH-CGIESEIVAGIPR 314 >3PBH-A nrPDB Length = 317 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 71/258 (27%), Positives = 118/258 (45%), Gaps = 48/258 (18%) Query: 114 RAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LSPQNL 167 + P S D R++ P +++QG CGSCWAF +V A+ ++ T ++ +S ++L Sbjct: 63 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 122 Query: 168 VDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYV---------GQEES 209 + C DGC GGY A+ + + +G+ S Y PY G Sbjct: 123 LTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 181 Query: 210 CM---------------YNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPVSVAIDASL 253 C Y+PT K K GY N EK + + + GPV A Sbjct: 182 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 240 Query: 254 TSFQFYSKGVYYDESCNSDNL-NHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312 + F Y GVY + + + HA+ +G+G++ G +W++ NSW +WG+ G+ + R Sbjct: 241 SDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 298 Query: 313 NKNNACGIAN--LASFPK 328 +++ CGI + +A P+ Sbjct: 299 GQDH-CGIESEVVAGIPR 315 >3CBK-A nrPDB Length = 266 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 70/258 (27%), Positives = 117/258 (45%), Gaps = 48/258 (18%) Query: 114 RAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LSPQNL 167 + P S D R++ P +++QG CGS WAF +V A+ ++ T ++ +S ++L Sbjct: 6 KLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSAEDL 65 Query: 168 VDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYV---------GQEES 209 + C DGC GGY A+ + + +G+ S Y PY G Sbjct: 66 LTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEAHVNGARPP 124 Query: 210 CM---------------YNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPVSVAIDASL 253 C Y+PT K K GY N EK + + + GPV A Sbjct: 125 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 183 Query: 254 TSFQFYSKGVYYDESCNSDNL-NHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312 + F Y GVY + + + HA+ +G+G++ G +W++ NSW +WG+ G+ + R Sbjct: 184 SDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILR 241 Query: 313 NKNNACGIAN--LASFPK 328 +++ CGI + +A P+ Sbjct: 242 GQDH-CGIESEVVAGIPR 258 >1EF7-A nrPDB Length = 242 Score = 82.0 bits (201), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 66/220 (30%), Positives = 105/220 (47%), Gaps = 30/220 (13%) Query: 111 WEGRAPDSVDYRKKGYVTPVKNQ---GQCGSCWAFSSVGALEGQLK-KKTGKLLN--LSP 164 W+ R D V+Y + +NQ CGSCWA +S A+ ++ K+ G + LS Sbjct: 5 WDWRNVDGVNY-----ASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 59 Query: 165 QNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKA---AK 220 QN++DC + C GG + + Y ++ GI E Y +++ C +N G + Sbjct: 60 QNVIDCGNAGS-CEGGNDLSVWDYAHQH-GIPDETCNNYQAKDQECDKFNQCGTCNEFKE 117 Query: 221 CRGYREIP----------EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCN 270 C R G EK + A GP+S I A+ Y+ G+Y E + Sbjct: 118 CHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMAT-ERLANYTGGIY-AEYQD 174 Query: 271 SDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 + +NH V G+GI G ++WI++NSWGE WG +G++ + Sbjct: 175 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 214 >1DEU-A nrPDB Length = 277 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 66/220 (30%), Positives = 105/220 (47%), Gaps = 30/220 (13%) Query: 111 WEGRAPDSVDYRKKGYVTPVKNQ---GQCGSCWAFSSVGALEGQLK-KKTGKLLN--LSP 164 W+ R D V+Y + +NQ CGSCWA +S A+ ++ K+ G + LS Sbjct: 40 WDWRNVDGVNY-----ASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 94 Query: 165 QNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKA---AK 220 QN++DC + C GG + + Y ++ GI E Y +++ C +N G + Sbjct: 95 QNVIDCGNAGS-CEGGNDLSVWDYAHQH-GIPDETCNNYQAKDQECDKFNQCGTCNEFKE 152 Query: 221 CRGYREIP----------EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCN 270 C R G EK + A GP+S I A+ Y+ G+Y E + Sbjct: 153 CHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMAT-ERLANYTGGIY-AEYQD 209 Query: 271 SDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 + +NH V G+GI G ++WI++NSWGE WG +G++ + Sbjct: 210 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 249 >4I05-A nrPDB Length = 285 Score = 80.1 bits (196), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 69/251 (27%), Positives = 109/251 (43%), Gaps = 44/251 (17%) Query: 110 EWEGRAPDSVDYRKK----GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LS 163 +W P S D RKK + +++Q +CGSCWAF +V A+ + ++G N LS Sbjct: 29 DWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELS 88 Query: 164 PQNLVDCV-SENDGCGGGYMTNAFQYVQKN---RGIDSE-----DAYPYVGQEESCM--Y 212 +L+ C S GC GG + A+ Y K G E + YP+ E Y Sbjct: 89 AVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKY 148 Query: 213 NPTGKA--------AKCRGYREIP--------------EGNEKALKRAVARVGPVSVAID 250 P G C+ + P + +EKA+++ + + GPV Sbjct: 149 PPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFT 208 Query: 251 ASLTSFQFYSKGVYYDESCNSDNLN-HAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYIL 309 F Y G+Y + + L HA+ +G+G++ +W+I NSW E+WG GY Sbjct: 209 V-YEDFLNYKSGIY--KHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFR 265 Query: 310 MARNKNNACGI 320 + R ++ C I Sbjct: 266 IVRGRDE-CSI 275 >5OGQ-A nrPDB Length = 254 Score = 77.8 bits (190), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 105/242 (43%), Gaps = 43/242 (17%) Query: 116 PDSVDYRKK----GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LSPQNLVD 169 P S D RKK + +++Q +CGSCWAF +V A+ + ++G N LS +L+ Sbjct: 4 PSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVDLLS 63 Query: 170 CV-SENDGCGGGYMTNAFQYVQKN---RGIDSE-----DAYPYVGQEESCM--YNPTGKA 218 C S GC GG + A+ Y K G E + YP+ E Y P G Sbjct: 64 CCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCGSK 123 Query: 219 --------AKCRGYREIP--------------EGNEKALKRAVARVGPVSVAIDASLTSF 256 C+ + P + +EKA+++ + + GPV F Sbjct: 124 IYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV-YEDF 182 Query: 257 QFYSKGVYYDESCNSDNLN-HAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 315 Y G+Y + + L HA+ +G+G++ +W+I NSW E+WG GY + R ++ Sbjct: 183 LNYKSGIY--KHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGRD 240 Query: 316 NA 317 Sbjct: 241 EC 242 >4HWY-A nrPDB Length = 340 Score = 77.4 bits (189), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 72/247 (29%), Positives = 101/247 (40%), Gaps = 34/247 (13%) Query: 110 EWEGRAP-----DSVDYRKKGYVTP-VKNQGQCGSCWAFSSVGALEGQLKKKTG-KLLNL 162 E E RAP DS + P + +Q CGSCWA ++ A+ + G + +++ Sbjct: 87 EEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHI 146 Query: 163 SPQNLVDCVSE-NDGCGGGYMTNAFQYVQKNRGID----------------SEDAYPYVG 205 S +L+ C S+ DGC GG A+ Y + S++ YP Sbjct: 147 SAGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCS 206 Query: 206 Q----EESCMY---NPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258 Q C Y +PT R + E R + GP VA D F Sbjct: 207 QFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDV-YEDFIA 265 Query: 259 YSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318 Y+ GVY+ S HAV VG+G G +W I NSW WG GY L+ R ++ C Sbjct: 266 YNSGVYHHVSGQYLG-GHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLI-RRGSSEC 323 Query: 319 GIANLAS 325 GI + S Sbjct: 324 GIEDGGS 330 >4I04-A nrPDB Length = 323 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 68/251 (27%), Positives = 108/251 (43%), Gaps = 44/251 (17%) Query: 110 EWEGRAPDSVDYRKK----GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLN--LS 163 +W P S D RKK + +++Q +CGS WAF +V A+ + ++G N LS Sbjct: 67 DWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQNVELS 126 Query: 164 PQNLVDCV-SENDGCGGGYMTNAFQYVQKN---RGIDSE-----DAYPYVGQEESCM--Y 212 +L+ C S GC GG + A+ Y K G E + YP+ E Y Sbjct: 127 AVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKY 186 Query: 213 NPTGKA--------AKCRGYREIP--------------EGNEKALKRAVARVGPVSVAID 250 P G C+ + P + +EKA+++ + + GPV Sbjct: 187 PPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFT 246 Query: 251 ASLTSFQFYSKGVYYDESCNSDNLN-HAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYIL 309 F Y G+Y + + L HA+ +G+G++ +W+I NSW E+WG GY Sbjct: 247 V-YEDFLNYKSGIY--KHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFR 303 Query: 310 MARNKNNACGI 320 + R ++ C I Sbjct: 304 IVRGRDE-CSI 313 >4OEL-A nrPDB Length = 370 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 53/178 (29%), Positives = 85/178 (47%), Gaps = 15/178 (8%) Query: 96 PLSHSRSNDTLYIP-EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154 PL+ L++P W+ R +++ V+PV+NQ CGSC++F+S+G LE +++ Sbjct: 195 PLTAEIQQKILHLPTSWDWRNVHGINF-----VSPVRNQASCGSCYSFASMGMLEARIRI 249 Query: 155 KT--GKLLNLSPQNLVDCVSENDGCGGGY-MTNAFQYVQKNRGIDSEDAYPYVGQEESCM 211 T + LSPQ +V C GC GG+ A +Y Q + G+ E +PY G + C Sbjct: 250 LTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQ-DFGLVEEACFPYTGTDSPCK 308 Query: 212 YNPTGKAAKCRGYREI----PEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYY 265 Y + NE +K + GP++VA + F Y KG+Y+ Sbjct: 309 MKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYH 365 >4CDF-B nrPDB Length = 166 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 51/160 (31%), Positives = 78/160 (48%), Gaps = 12/160 (7%) Query: 116 PDSVDYRKK---GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKT--GKLLNLSPQNLVDC 170 P S D+R +V+PV+NQ CGSC++F+S+G LE +++ T + LSPQ +V C Sbjct: 4 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 63 Query: 171 VSENDGCGGGY-MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREI-- 227 GC GG+ A +Y Q + G+ E +PY G + C Y + Sbjct: 64 SQYAQGCEGGFPYLIAGKYAQ-DFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGG 122 Query: 228 --PEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYY 265 NE +K + GP++VA + F Y KG+Y+ Sbjct: 123 FYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYH 161 >2DCB-A nrPDB Length = 256 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/245 (25%), Positives = 109/245 (44%), Gaps = 44/245 (17%) Query: 116 PDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNL--SPQNLVD 169 P+S D R++ P +++QG CGSCWAF +V A+ ++ + +N+ S ++++ Sbjct: 2 PESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDMLT 61 Query: 170 CVSENDGCGGG--YMTNAFQYVQKNRGIDSEDAY-PYVGQEE----SCMYNPTGKAAKCR 222 C G G + + A+ + K +G+ S Y +VG C ++ G C Sbjct: 62 CCGGECGDGCNGGFPSGAWNFWTK-KGLVSGGLYNSHVGCRPYSIPPCEHHVNGSRPPCT 120 Query: 223 GYREIPE---------------------------GNEKALKRAVARVGPVSVAIDASLTS 255 G + P+ NEK + + + GPV A + Sbjct: 121 GEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSV-YSD 179 Query: 256 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 315 F Y GVY S HA+ +G+G++ G +W++ NSW +WG+ G+ + R ++ Sbjct: 180 FLLYKSGVYQHVS-GEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQD 238 Query: 316 NACGI 320 + CGI Sbjct: 239 H-CGI 242 >1CSB-B nrPDB Length = 205 Score = 61.6 bits (148), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 54/206 (26%), Positives = 90/206 (43%), Gaps = 42/206 (20%) Query: 160 LNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYV------ 204 + +S ++L+ C DGC GGY A+ + + +G+ S Y PY Sbjct: 3 VEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPYSIPPCEH 61 Query: 205 ---GQEESCM---------------YNPTGKAAKCRGYREIPEGN-EKALKRAVARVGPV 245 G C Y+PT K K GY N EK + + + GPV Sbjct: 62 HVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPV 121 Query: 246 SVAIDASLTSFQFYSKGVYYDESCNSDNL-NHAVLAVGYGIQKGNKHWIIKNSWGENWGN 304 A + F Y GVY + + + HA+ +G+G++ G +W++ NSW +WG+ Sbjct: 122 EGAFSV-YSDFLLYKSGVY--QHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 178 Query: 305 KGYILMARNKNNACGIAN--LASFPK 328 G+ + R +++ CGI + +A P+ Sbjct: 179 NGFFKILRGQDH-CGIESEVVAGIPR 203 >1SP4-B nrPDB Length = 205 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 29/90 (32%), Positives = 48/90 (53%), Gaps = 3/90 (3%) Query: 231 NEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNK 290 NEK + + + GPV A + F Y GVY S HA+ +G+G++ G Sbjct: 108 NEKEIMAEIYKNGPVEGAFSV-YSDFLLYKSGVYQHVS-GEIMGGHAIRILGWGVENGTP 165 Query: 291 HWIIKNSWGENWGNKGYILMARNKNNACGI 320 +W++ NSW +WG+ G+ + R +++ CGI Sbjct: 166 YWLVGNSWNTDWGDNGFFKILRGQDH-CGI 194 >4OEM-B nrPDB Length = 70 Score = 52.0 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 25/52 (48%), Positives = 31/52 (59%), Gaps = 3/52 (5%) Query: 275 NHAVLAVGYGIQK--GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLA 324 NHAVL VGYG G +WI+KNSWG WG GY + R + C I ++A Sbjct: 10 NHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRG-TDECAIESIA 60 >3CH2-X nrPDB Length = 265 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 59/215 (27%), Positives = 90/215 (41%), Gaps = 38/215 (17%) Query: 130 VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV--SENDGCGGGYMTNAFQ 187 V++QG C + W F+S LE K + +S + +C D C G F Sbjct: 24 VEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEFL 83 Query: 188 YVQKNRG-IDSEDAYPY--VGQEESC----------------MYNPT------GK---AA 219 + ++ G + +E YPY V E C ++N GK A Sbjct: 84 QIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTAY 143 Query: 220 KCRGYREIPEGNEKALKRAVARVGPVSVAIDA-SLTSFQFYSKGVYYDESCNSDNLNHAV 278 + + + + K +K V G V I A ++ ++F K V C D +HAV Sbjct: 144 ESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEFSGKKV--QNLCGDDTADHAV 201 Query: 279 LAVGYGI---QKGNK--HWIIKNSWGENWGNKGYI 308 VGYG +G K +WI++NSWG WG++GY Sbjct: 202 NIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYF 236 >5FPW-A nrPDB Length = 321 Score = 49.7 bits (117), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLN-HAVLAVGYGIQKGNK 290 E+ KR + GP VA+ T Y GVY + D L AV VG+G G Sbjct: 221 EEDYKRELYFNGPF-VAVFYVYTDLFAYKSGVY--RHVDGDFLGGTAVKVVGWGKLNGTP 277 Query: 291 HWIIKNSWGENWGNKGYILMARNKNNACGIANL 323 +W + N+W +WG GY+L+ R NN C I +L Sbjct: 278 YWKVANTWDTDWGMDGYLLILRG-NNECNIEHL 309 >4D59-A nrPDB Length = 406 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 54/215 (25%), Positives = 83/215 (38%), Gaps = 35/215 (16%) Query: 125 GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN------DGCG 178 G TP KNQG + W+FS + LE LK K +LS ++L + D Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 70 Query: 179 GGYMTNAFQYVQKNRGIDSEDAYPY-VGQEESCMYNPTGKAAKCRGYREIP----EGNEK 233 G A Y+ G E PY + E P+ + +++ Sbjct: 71 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKE 130 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESC-NSDN----LNHAVLAVGYGIQ-- 286 +K A+ + G V+ + + YS DE+ N N LNHAV VG+ Sbjct: 131 TVKNAIMQYGSVT-------SGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYS 183 Query: 287 ----------KGNKHWIIKNSWGENWGNKGYILMA 311 + N W++K+SWGE KG+ ++ Sbjct: 184 KDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWIS 218 >4CI7-A nrPDB Length = 470 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 69/284 (24%), Positives = 109/284 (38%), Gaps = 51/284 (17%) Query: 67 GVHTYELA---MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRK 123 GV T E + + +L D+ + + K G+ +P H TL +GR+ Y+ Sbjct: 11 GVETAEYSESYLQYLEDVKNGDTA-KYNGV-IPFPHEMEGTTL---RNKGRSSLPSAYKS 65 Query: 124 K--------GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN- 174 G TP KNQG + W+FS + LE LK K +LS ++L + Sbjct: 66 SVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGK 125 Query: 175 -----DGCGGGYMTNAFQYVQKNRGIDSEDAYPY-VGQEESCMYNPTGKAAKCRGYREIP 228 D G A Y+ G E PY + E P+ + Sbjct: 126 YGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTD 185 Query: 229 ----EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESC-NSDN----LNHAVL 279 +++ +K A+ + G V+ + + YS DE+ N N LNHAV Sbjct: 186 VVRLNKDKETVKNAIMQYGSVT-------SGYAHYSTYFNKDETAYNCTNKRAPLNHAVA 238 Query: 280 AVGYGIQ------------KGNKHWIIKNSWGENWGNKGYILMA 311 VG+ + N W++K+SWGE KG+ ++ Sbjct: 239 IVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWIS 282 >2L95-A nrPDB Length = 80 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Query: 21 ILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGD 80 + D W +K K Y + D + RR I+ ++ I HN + G T+++ +NHL D Sbjct: 5 VSDEEWVEYKSKFDKNYEAEED-LMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLAD 63 Query: 81 MTSEEVVQKMTGLKVP 96 +T EE Q+ +G KVP Sbjct: 64 LTPEEFAQR-SGKKVP 78 >3OIS-A nrPDB Length = 291 Score = 37.0 bits (84), Expect = 0.013, Method: Compositional matrix adjust. Identities = 18/35 (51%), Positives = 22/35 (62%), Gaps = 2/35 (5%) Query: 276 HAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 HAVL VGY + +H+ I+NSWG N G GY M Sbjct: 237 HAVLCVGYDDEI--RHFRIRNSWGNNVGEDGYFWM 269 >5WDK-A nrPDB Length = 401 Score = 34.7 bits (78), Expect = 0.054, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 20/30 (66%) Query: 123 KKGYVTPVKNQGQCGSCWAFSSVGALEGQL 152 K+ +T VKNQ + G+CW +SS LE +L Sbjct: 36 KENPITSVKNQNRAGTCWCYSSYSFLESEL 65 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 12/22 (54%), Positives = 18/22 (81%), Gaps = 3/22 (13%) Query: 283 YGI---QKGNKHWIIKNSWGEN 301 YGI Q+GN+++++KNSWG N Sbjct: 341 YGIAKDQEGNEYYMVKNSWGTN 362 >4K7C-A nrPDB Length = 446 Score = 33.1 bits (74), Expect = 0.18, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 21/37 (56%), Gaps = 1/37 (2%) Query: 274 LNHAVLAVGYGIQKGN-KHWIIKNSWGENWGNKGYIL 309 + HA++ G + G W ++NSWGE G KGY + Sbjct: 362 MTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYFV 398 >2CB5-A nrPDB Length = 453 Score = 31.6 bits (70), Expect = 0.47, Method: Compositional matrix adjust. Identities = 11/20 (55%), Positives = 16/20 (80%) Query: 292 WIIKNSWGENWGNKGYILMA 311 W ++NSWGE+ G+KGY+ M Sbjct: 391 WRVENSWGEDHGHKGYLCMT 410 >1URT-A nrPDB Length = 248 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 16/74 (21%), Positives = 35/74 (47%), Gaps = 3/74 (4%) Query: 241 RVGPVSVAIDASLTSFQF---YSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNS 297 ++ P+ V+ DA+ + + ++ V +D+SC ++ L Y +++ + HW + Sbjct: 22 QLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISGGPLGNHYRLKQFHFHWGATDE 81 Query: 298 WGENWGNKGYILMA 311 WG G+ A Sbjct: 82 WGSEHAVDGHTYPA 95 >3SKS-A nrPDB Length = 567 Score = 27.7 bits (60), Expect = 6.7, Method: Compositional matrix adjust. Identities = 38/187 (20%), Positives = 73/187 (39%), Gaps = 26/187 (13%) Query: 121 YRKKGYVTPVKNQGQCGSC-WAFSSVGALEGQLKKKTGKLLNLSPQN-LVDCVSENDGCG 178 Y + + P N G W + + +L +T + N N L+D V++ G Sbjct: 269 YYDENFEFPTGNPTPKGDADWIVNHGKTMYKELSAETDEFFNFMLDNDLLDLVAKKGKAG 328 Query: 179 GGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYR--EIPEGNEKALK 236 GGY T Y++ + + + + + G A + R EIPE N Sbjct: 329 GGYCT----YIENYKAPFIFSNFNGTSGDIDVLTHEAGHAFQVYESRKFEIPEYN----- 379 Query: 237 RAVARVGPVSVAIDASLTSFQFYS---KGVYYDESCNSDNLNH---AVLAVGYGIQKGN- 289 P A + S +F++ ++++E + +H A+L + YG+ Sbjct: 380 ------WPTYEACEIHSMSMEFFTWPWMKLFFEEDADKYYFSHLSSALLFLPYGVSVDEY 433 Query: 290 KHWIIKN 296 +H++ +N Sbjct: 434 QHYVYEN 440 >1A6R-A nrPDB Length = 471 Score = 27.3 bits (59), Expect = 8.7, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 7/53 (13%) Query: 263 VYYDESCNSDNLNHAVLAVGYGIQKGNK---HWIIKNSWGENWGNKGYILMAR 312 + Y ES + HA+L G + + +K + ++NSWG++ G G +M + Sbjct: 377 IRYHESL----MTHAMLITGCHVDETSKLPLRYRVENSWGKDSGKDGLYVMTQ 425 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 7PCK-A nrPDB 468 e-132 2C0Y-A nrPDB 409 e-115 1CJL-A nrPDB 393 e-110 3QJ3-A nrPDB 382 e-106 3QT4-A nrPDB 367 e-102 6CZS-A nrPDB 363 e-101 1PCI-A nrPDB 359 1e-99 2O6X-A nrPDB 355 1e-98 4QRX-A nrPDB 349 8e-97 5JA7-A nrPDB 345 1e-95 3HWN-A nrPDB 344 3e-95 5EF4-A nrPDB 341 2e-94 6BKI-A nrPDB 323 7e-89 3OF9-A nrPDB 319 1e-87 3KFQ-A nrPDB 316 9e-87 4P6E-A nrPDB 315 3e-86 4BS5-A nrPDB 309 1e-84 2VHS-A nrPDB 301 2e-82 1S4V-A nrPDB 299 8e-82 1CQD-A nrPDB 299 9e-82 2PNS-A nrPDB 291 3e-79 2FO5-A nrPDB 291 3e-79 3BCN-A nrPDB 290 5e-79 1IWD-A nrPDB 289 7e-79 3P5W-A nrPDB 289 1e-78 4YYR-A nrPDB 286 8e-78 1XKG-A nrPDB 286 9e-78 1O0E-A nrPDB 286 1e-77 5JT8-A nrPDB 285 2e-77 1NB3-A nrPDB 284 3e-77 3F75-A nrPDB 284 5e-77 1AEC-A nrPDB 281 3e-76 4YYW-A nrPDB 278 3e-75 3PDF-A nrPDB 278 3e-75 1YAL-A nrPDB 275 2e-74 2ACT-A nrPDB 274 3e-74 2BDZ-A nrPDB 272 1e-73 1PPO-A nrPDB 269 2e-72 6MIS-A nrPDB 264 4e-71 2CIO-A nrPDB 262 1e-70 5A24-A nrPDB 262 2e-70 1MIR-A nrPDB 260 7e-70 4YYQ-A nrPDB 259 8e-70 1ICF-A nrPDB 258 2e-69 3U8E-A nrPDB 257 5e-69 2B1M-A nrPDB 256 1e-68 1GEC-E nrPDB 256 1e-68 3PBH-A nrPDB 251 4e-67 1JQP-A nrPDB 249 1e-66 6EXO-A nrPDB 247 3e-66 3IOQ-A nrPDB 246 2e-65 3BPF-A nrPDB 241 4e-64 4PI3-A nrPDB 238 2e-63 5VPK-A nrPDB 234 3e-62 3BPM-A nrPDB 234 5e-62 5VCN-A nrPDB 233 8e-62 1CPJ-A nrPDB 223 9e-59 1M6D-A nrPDB 222 1e-58 3CBK-A nrPDB 214 4e-56 4OEL-A nrPDB 203 7e-53 4I04-A nrPDB 202 1e-52 4I05-A nrPDB 202 2e-52 4HWY-A nrPDB 198 2e-51 5OGQ-A nrPDB 194 5e-50 2DCB-A nrPDB 189 2e-48 4CI7-A nrPDB 170 1e-42 4CDF-B nrPDB 169 2e-42 1DEU-A nrPDB 168 3e-42 5I4H-A nrPDB 166 1e-41 1EF7-A nrPDB 164 7e-41 1CSB-B nrPDB 156 2e-38 4D59-A nrPDB 152 1e-37 5I4H-B nrPDB 150 5e-37 3CH2-X nrPDB 145 3e-35 5FPW-A nrPDB 143 1e-34 1SP4-B nrPDB 128 2e-30 4OEM-B nrPDB 85 5e-17 2L95-A nrPDB 78 6e-15 Sequences not found previously or not previously below threshold: 3OIS-A nrPDB 57 1e-08 5WDK-A nrPDB 44 7e-05 4K7C-A nrPDB 44 1e-04 2CB5-A nrPDB 34 0.11 2QGM-A nrPDB 33 0.12 1A6R-A nrPDB 32 0.49 1X9Y-A nrPDB 32 0.54 1G0D-A nrPDB 32 0.54 2V0O-A nrPDB 30 1.3 1L9N-A nrPDB 30 1.5 2Z51-A nrPDB 30 2.0 3EUP-A nrPDB 29 2.5 5ZRD-A nrPDB 28 4.0 2WQK-A nrPDB 28 4.5 4WFK-A nrPDB 28 5.6 5DMY-A nrPDB 28 6.7 4Z04-A nrPDB 28 7.4 1H33-A nrPDB 28 8.0 2JNV-A nrPDB 27 9.4 4CTH-A nrPDB 27 9.6 >7PCK-A nrPDB Length = 314 Score = 468 bits (1204), Expect = e-132, Method: Composition-based stats. Identities = 314/314 (100%), Positives = 314/314 (100%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM Sbjct: 1 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 60 Query: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ Sbjct: 61 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 120 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 195 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI Sbjct: 121 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 180 Query: 196 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTS 255 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTS Sbjct: 181 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTS 240 Query: 256 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 315 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN Sbjct: 241 FQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 300 Query: 316 NACGIANLASFPKM 329 NACGIANLASFPKM Sbjct: 301 NACGIANLASFPKM 314 >2C0Y-A nrPDB Length = 315 Score = 409 bits (1052), Expect = e-115, Method: Composition-based stats. Identities = 176/317 (55%), Positives = 222/317 (70%), Gaps = 6/317 (1%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 L+ + LD HW LWKKT+ KQY K +E RRLIWEKNLK++ +HNLE S+G+H+Y+L M Sbjct: 2 LHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGM 61 Query: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135 NHLGDMTSEEV+ M+ L+VP R + Y PDSVD+R+KG VT VK QG Sbjct: 62 NHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGS 119 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS---ENDGCGGGYMTNAFQYVQKN 192 CG+ WAFS+VGALE QLK KTGKL++LS QNLVDC + N GC GG+MT AFQY+ N Sbjct: 120 CGAAWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDN 179 Query: 193 RGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDAS 252 +GIDS+ +YPY ++ C Y+ +AA C Y E+P G E LK AVA GPVSV +DA Sbjct: 180 KGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDAR 239 Query: 253 LTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312 SF Y GVYY+ SC + N+NH VL VGYG G ++W++KNSWG N+G +GYI MAR Sbjct: 240 HPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMAR 298 Query: 313 NKNNACGIANLASFPKM 329 NK N CGIA+ S+P++ Sbjct: 299 NKGNHCGIASFPSYPEI 315 >1CJL-A nrPDB Length = 312 Score = 393 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 165/316 (52%), Positives = 214/316 (67%), Gaps = 15/316 (4%) Query: 22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81 L+ W WK H + Y +E RR +WEKN+K I +HN E G H++ +AMN GDM Sbjct: 4 LEAQWTKWKAMHNRLYGMN-EEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDM 62 Query: 82 TSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSC 139 TSEE Q M GL + P + L+ AP SVD+R+KGYVTPVKNQGQCGS Sbjct: 63 TSEEFRQVMNGLQNRKPRKGKVFQEPLFY-----EAPRSVDWREKGYVTPVKNQGQCGSS 117 Query: 140 WAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENDGCGGGYMTNAFQYVQKNRGIDS 197 WAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC GG M AFQYVQ N G+DS Sbjct: 118 WAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPEGNEGCNGGLMDYAFQYVQDNGGLDS 177 Query: 198 EDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQ 257 E++YPY EESC YNP A G+ +IP+ EKAL +AVA VGP+SVAIDA SF Sbjct: 178 EESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFL 236 Query: 258 FYSKGVYYDESCNSDNLNHAVLAVGYGIQ----KGNKHWIIKNSWGENWGNKGYILMARN 313 FY +G+Y++ C+S++++H VL VGYG + GNK+W++KNSWGE WG GY+ MA++ Sbjct: 237 FYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDGNKYWLVKNSWGEEWGMGGYVKMAKD 296 Query: 314 KNNACGIANLASFPKM 329 + N CGIA+ AS+P + Sbjct: 297 RRNHCGIASAASYPTV 312 >3QJ3-A nrPDB Length = 331 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 140/324 (43%), Positives = 187/324 (57%), Gaps = 9/324 (2%) Query: 13 SFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYE 72 AL P + WE +K T+ + Y N +E R+ I++K L+ HN + G+ +Y Sbjct: 10 GSAL-PSTFVAEKWENFKTTYARSYVNAKEETFRKQIFQKKLETFEEHNEKYRQGLVSYT 68 Query: 73 LAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEG-----RAPDSVDYRKKGYV 127 L +N DMT EE+ GL +P ++ + E G R P S D+R +G V Sbjct: 69 LGVNLFTDMTPEEMKAYTHGLIMPADLHKNGIPIKTREDLGLNASVRYPASFDWRDQGMV 128 Query: 128 TPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLL--NLSPQNLVDCVSENDGCGGGYMTNA 185 +PVKNQG CGS WAFSS GA+E Q+K G ++S Q LVDCV GC GG+M +A Sbjct: 129 SPVKNQGSCGSSWAFSSTGAIESQMKIANGAGYDSSVSEQQLVDCVPNALGCSGGWMNDA 188 Query: 186 FQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPV 245 F YV +N GIDSE AYPY + +C Y+P AA+ GY + +E L VA GPV Sbjct: 189 FTYVAQNGGIDSEGAYPYEMADGNCHYDPNQVAARLSGYVYLSGPDENMLADMVATKGPV 248 Query: 246 SVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNK 305 +VA DA F YS GVYY+ +C ++ HAVL VGYG + G +W++KNSWG+ WG Sbjct: 249 AVAFDAD-DPFGSYSGGVYYNPTCETNKFTHAVLIVGYGNENGQDYWLVKNSWGDGWGLD 307 Query: 306 GYILMARNKNNACGIANLASFPKM 329 GY +ARN NN CGIA +AS P + Sbjct: 308 GYFKIARNANNHCGIAGVASVPTL 331 >3QT4-A nrPDB Length = 329 Score = 367 bits (941), Expect = e-102, Method: Composition-based stats. Identities = 138/316 (43%), Positives = 193/316 (61%), Gaps = 9/316 (2%) Query: 18 PEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNH 77 P+ + W +K TH+K Y++ ++EI R+LI++ N+ I+ HN + G TY AMN Sbjct: 19 PKSLFQEQWSQFKLTHKKSYSSPIEEIRRQLIFKDNVAKIAEHNAKFEKGEVTYSKAMNQ 78 Query: 78 LGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAP--DSVDYRKKGYVTPVKNQGQ 135 GDM+ EE + + K + + L +P + P SVD+R V+ VK+QGQ Sbjct: 79 FGDMSKEEFLAYVNRGKA--QKPKHPENLRMPYVSSKKPLAASVDWRSN-AVSEVKDQGQ 135 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENDGCGGGYMTNAFQYVQKNR 193 CGS W+FS+ GA+EGQL + G+L +LS QNL+DC S N GC GG+M +AF Y+ + Sbjct: 136 CGSSWSFSTTGAVEGQLALQRGRLTSLSEQNLIDCSSSYGNAGCDGGWMDSAFSYIH-DY 194 Query: 194 GIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASL 253 GI SE AYPY Q + C ++ + GY ++P G+E +L AV + GPV+VAIDA+ Sbjct: 195 GIMSESAYPYEAQGDYCRFDSSQSVTTLSGYYDLPSGDENSLADAVGQAGPVAVAIDAT- 253 Query: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313 QFYS G++YD++CN +LNH VL VGYG G +WI+KNSWG WG GY RN Sbjct: 254 DELQFYSGGLFYDQTCNQSDLNHGVLVVGYGSDNGQDYWILKNSWGSGWGESGYWRQVRN 313 Query: 314 KNNACGIANLASFPKM 329 N CGIA AS+P + Sbjct: 314 YGNNCGIATAASYPAL 329 >6CZS-A nrPDB Length = 335 Score = 363 bits (931), Expect = e-101, Method: Composition-based stats. Identities = 132/333 (39%), Positives = 181/333 (54%), Gaps = 18/333 (5%) Query: 3 GLKVLLLPVVSFA-LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHN 61 G +L +PV A L + H++ W HRK Y+ + R + N + I+ HN Sbjct: 11 GAWLLGVPVCGAAELCVNSLEKFHFKSWMSKHRKTYSTEEYH-HRLQTFASNWRKINAHN 69 Query: 62 LEASLGVHTYELAMNHLGDMTSEEVVQKM-TGLKVPLSHSRSNDTLYIPEWEGRAPDSVD 120 G HT+++A+N DM+ E+ K S ++S G P SVD Sbjct: 70 N----GNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKS----NYLRGTGPYPPSVD 121 Query: 121 YRKKG-YVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGC 177 +RKKG +V+PVKNQG CGS W FS+ GALE + TGK+L+L+ Q LVDC + N GC Sbjct: 122 WRKKGNFVSPVKNQGACGSSWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGC 181 Query: 178 GGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKR 237 GG + AF+Y+ N+GI ED YPY G++ C + P + I +E+A+ Sbjct: 182 QGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVE 241 Query: 238 AVARVGPVSVAIDASLTSFQFYSKGVYYDESCN--SDNLNHAVLAVGYGIQKGNKHWIIK 295 AVA PVS A + + F Y G+Y SC+ D +NHAVLAVGYG + G +WI+K Sbjct: 242 AVALYNPVSFAFEVT-QDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVK 300 Query: 296 NSWGENWGNKGYILMARNKNNACGIANLASFPK 328 NSWG WG GY L+ R K N CG+A AS+P Sbjct: 301 NSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 332 >1PCI-A nrPDB Length = 322 Score = 359 bits (921), Expect = 1e-99, Method: Composition-based stats. Identities = 119/317 (37%), Positives = 168/317 (52%), Gaps = 12/317 (3%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 L E L + W H K Y N +++ R I++ NL YI N ++Y L + Sbjct: 12 LTSTERLIQLFNSWMLNHNKFYENVDEKLYRFEIFKDNLNYIDETN----KKNNSYWLGL 67 Query: 76 NHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQ 135 N D++++E +K G + + +S D +I E P++VD+RKKG VTPV++QG Sbjct: 68 NEFADLSNDEFNEKYVGSLIDATIEQSYDEEFINEDIVNLPENVDWRKKGAVTPVRHQGS 127 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 195 CGSCWAFS+V +EG K +TGKL+ LS Q LVDC + GC GGY A +YV KN GI Sbjct: 128 CGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRSHGCKGGYPPYALEYVAKN-GI 186 Query: 196 DSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLT 254 YPY ++ +C G K G + NE L A+A+ PVSV +++ Sbjct: 187 HLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEGNLLNAIAKQ-PVSVVVESKGR 245 Query: 255 SFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNK 314 FQ Y G++ ++ AV AVGYG G + +IKNSWG WG KGYI + R Sbjct: 246 PFQLYKGGIFEGPC--GTKVDGAVTAVGYGKSGGKGYILIKNSWGTAWGEKGYIRIKRAP 303 Query: 315 NNA---CGIANLASFPK 328 N+ CG+ + +P Sbjct: 304 GNSPGVCGLYKSSYYPT 320 >2O6X-A nrPDB Length = 310 Score = 355 bits (912), Expect = 1e-98, Method: Composition-based stats. Identities = 139/309 (44%), Positives = 183/309 (59%), Gaps = 6/309 (1%) Query: 23 DTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMT 82 D W WK+ + K+YN D+ RR IWEKN+K+I HNL LG+ TY L +N DMT Sbjct: 2 DDLWHQWKRMYNKEYNGADDQ-HRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMT 60 Query: 83 SEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAF 142 EE K S S+ Y PD +D+R+ GYVT VK+QG CGS WAF Sbjct: 61 FEEFKAKYLTEMSRASDILSHGVPY-EANNRAVPDKIDWRESGYVTEVKDQGNCGSGWAF 119 Query: 143 SSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENDGCGGGYMTNAFQYVQKNRGIDSEDA 200 S+ G +EGQ K ++ S Q LVDC N+GCGGG M NA+QY+++ G+++E + Sbjct: 120 STTGTMEGQYMKNERTSISFSEQQLVDCSRPWGNNGCGGGLMENAYQYLKQ-FGLETESS 178 Query: 201 YPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYS 260 YPY E C YN AK G+ + G+E LK V GP +VA+D + F Y Sbjct: 179 YPYTAVEGQCRYNKQLGVAKVTGFYTVHSGSEVELKNLVGAEGPAAVAVDVE-SDFMMYR 237 Query: 261 KGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGI 320 G+Y ++C+ +NHAVLAVGYG Q G +WI+KNSWG +WG +GYI M RN+ N CGI Sbjct: 238 SGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGLSWGERGYIRMVRNRGNMCGI 297 Query: 321 ANLASFPKM 329 A+LAS P + Sbjct: 298 ASLASLPMV 306 >4QRX-A nrPDB Length = 363 Score = 349 bits (896), Expect = 8e-97, Method: Composition-based stats. Identities = 118/318 (37%), Positives = 168/318 (52%), Gaps = 17/318 (5%) Query: 16 LYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAM 75 L E L +E W H K Y N ++I R I++ NLKYI N ++Y L + Sbjct: 56 LTSTERLIQLFESWMLKHNKIYKNIDEKIYRFEIFKDNLKYIDETN----KKNNSYWLGL 111 Query: 76 NHLGDMTSEEVVQKMTGLKV-PLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134 N DM+++E +K TG + + + + + + P+ VD+R+KG VTPVKNQG Sbjct: 112 NVFADMSNDEFKEKYTGSIAGNYTTTELSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQG 171 Query: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194 CGS WAFS+V +E +K +TG L S Q L+DC + GC GGY +A Q V + G Sbjct: 172 SCGSAWAFSAVSTIESIIKIRTGNLNEYSEQELLDCDRRSYGCNGGYPWSALQLVAQ-YG 230 Query: 195 IDSEDAYPYVGQEESCMYNPTGK-AAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASL 253 I + YPY G + C G AAK G R++ NE AL ++A PVSV ++A+ Sbjct: 231 IHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEGALLYSIANQ-PVSVVLEAAG 289 Query: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313 FQ Y G++ N ++HAV AVGYG + +I+NSWG WG GYI + R Sbjct: 290 KDFQLYRGGIFVGPCGN--KVDHAVAAVGYG----PNYILIRNSWGTGWGENGYIRIKRG 343 Query: 314 KNNA---CGIANLASFPK 328 N+ CG+ + +P Sbjct: 344 TGNSYGVCGLYTSSFYPV 361 >5JA7-A nrPDB Length = 223 Score = 345 bits (885), Expect = 1e-95, Method: Composition-based stats. Identities = 222/223 (99%), Positives = 222/223 (99%) Query: 107 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQN 166 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGS WAFSSVGALEGQLKKKTGKLLNLSPQN Sbjct: 1 YIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSSWAFSSVGALEGQLKKKTGKLLNLSPQN 60 Query: 167 LVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE 226 LVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE Sbjct: 61 LVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE 120 Query: 227 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ 286 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ Sbjct: 121 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ 180 Query: 287 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM Sbjct: 181 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 223 >3HWN-A nrPDB Length = 258 Score = 344 bits (883), Expect = 3e-95, Method: Composition-based stats. Identities = 144/264 (54%), Positives = 184/264 (69%), Gaps = 14/264 (5%) Query: 74 AMNHLGDMTSEEVVQKMTGL--KVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVK 131 AMN GDMTSEE Q M G + P + L+ AP SVD+R+KGYVTPVK Sbjct: 1 AMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFY-----EAPRSVDWREKGYVTPVK 55 Query: 132 NQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV--SENDGCGGGYMTNAFQYV 189 NQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC N+GC GG M AFQYV Sbjct: 56 NQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYV 115 Query: 190 QKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAI 249 Q N G+DSE++YPY EESC YNP A G+ +IP+ EKAL +AVA VGP+SVAI Sbjct: 116 QDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPK-QEKALMKAVATVGPISVAI 174 Query: 250 DASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ----KGNKHWIIKNSWGENWGNK 305 DA SF FY +G+Y++ C+S++++H VL VGYG + NK+W++KNSWGE WG Sbjct: 175 DAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMG 234 Query: 306 GYILMARNKNNACGIANLASFPKM 329 GY+ MA+++ N CGIA+ AS+P + Sbjct: 235 GYVKMAKDRRNHCGIASAASYPTV 258 >5EF4-A nrPDB Length = 385 Score = 341 bits (875), Expect = 2e-94, Method: Composition-based stats. Identities = 131/338 (38%), Positives = 176/338 (52%), Gaps = 23/338 (6%) Query: 8 LLPVVSFALYPEEILDTHWELWKKTH---RKQYNNKVDEISRRLIWEKNLKYISIHNLEA 64 L+P S + E E + + R+Q+N ++ R +++ N++ I N Sbjct: 14 LVPRGSHMFHYHERELESEEGFMGMYDRWREQHNIEMRSPERFNVFKYNVRRIHESN--- 70 Query: 65 SLGVHTYELAMNHLGDMTSEEVVQKMTGLKV----------PLSHSRSNDTLYIPEWEGR 114 Y+L +N DMT+ E V K+ P S + +I + Sbjct: 71 -KMDKPYKLKVNEFADMTNLEFVNTYANSKISHFQALRGSAPGSIDTDPNKDFIYANVTK 129 Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 PD VD+R+K VT VK QG CGSCWAF++V ALEG +TGKL+ S Q LVDC N Sbjct: 130 IPDKVDWREKNAVTDVKGQGGCGSCWAFAAVVALEGINAIRTGKLVKFSEQQLVDCDMTN 189 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC GG M AF YV K+ GI E +YPYVG+ E+C K G + +P +E+A Sbjct: 190 AGCDGGLMEPAFTYVIKHGGIAPEASYPYVGKRETCDKAKIKDVLKIDGRQNVPGLDEEA 249 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG-IQKGNKHWI 293 L++AVA PV+ I S QFYS+GVY C ++ NH V VGYG +KG K W Sbjct: 250 LRKAVAHQ-PVATGIQLSGHGLQFYSEGVYTG-DCGTEP-NHGVGIVGYGENEKGIKFWT 306 Query: 294 IKNSWGENWGNKGYILMARN--KNNACGIANLASFPKM 329 +KNSWG WG KGYI + R K CG+A +SFP M Sbjct: 307 VKNSWGPTWGEKGYIHLQRGARKEGLCGVAMHSSFPIM 344 >6BKI-A nrPDB Length = 215 Score = 323 bits (828), Expect = 7e-89, Method: Composition-based stats. Identities = 185/214 (86%), Positives = 199/214 (92%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 PDS+DYRKKGYVTPVKNQGQCGSCWAFSS GALEGQLKKKTGKLL LSPQNLVDCV+EN Sbjct: 2 PDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENY 61 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GCGGGYMT AFQYVQ+N GIDSEDAYPYVGQ+ESCMYN KAAKCRGYREIP GNEKAL Sbjct: 62 GCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNAAAKAAKCRGYREIPVGNEKAL 121 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIK 295 KRAVARVGP+SV+IDASL SFQFYS+GVYYDE+C+ DN+NHAVL VGYG QKG+KHWIIK Sbjct: 122 KRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIK 181 Query: 296 NSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 NSWGE+WGNKGY L+ARNKNNACGI N+ASFPKM Sbjct: 182 NSWGESWGNKGYALLARNKNNACGITNMASFPKM 215 >3OF9-A nrPDB Length = 221 Score = 319 bits (818), Expect = 1e-87, Method: Composition-based stats. Identities = 129/222 (58%), Positives = 166/222 (74%), Gaps = 7/222 (3%) Query: 114 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV-- 171 AP SVD+R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 172 SENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGN 231 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-Q 119 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ----K 287 EKAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + Sbjct: 120 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 179 Query: 288 GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 NK+W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 180 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 221 >3KFQ-A nrPDB Length = 221 Score = 316 bits (809), Expect = 9e-87, Method: Composition-based stats. Identities = 127/221 (57%), Positives = 163/221 (73%), Gaps = 6/221 (2%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV--S 172 P SVD+RKKGYVTPVKNQ QCGSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC Sbjct: 1 LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N GC GG+M AFQYV++N G+DSE++YPYV +E C Y P A+ G+ + G E Sbjct: 61 GNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVAQDTGFTVVAPGKE 120 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN--- 289 KAL +AVA VGP+SVA+DA +SFQFY G+Y++ C+S NL+H VL VGYG + N Sbjct: 121 KALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSDN 180 Query: 290 -KHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 K+W++KNSWG WG+ GY+ +A++KNN CGIA AS+P + Sbjct: 181 SKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 221 >4P6E-A nrPDB Length = 230 Score = 315 bits (806), Expect = 3e-86, Method: Composition-based stats. Identities = 125/223 (56%), Positives = 156/223 (69%), Gaps = 4/223 (1%) Query: 110 EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVD 169 PDSVD+R+KG VT VK QG CG+CWAFS+VGALE QLK KTGKL++LS QNLVD Sbjct: 2 NPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVD 61 Query: 170 CVS---ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYRE 226 C + N GC GG+MT AFQY+ N+GIDS+ +YPY ++ C Y+ +AA C Y E Sbjct: 62 CSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTE 121 Query: 227 IPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ 286 +P G E LK AVA GPVSV +DA SF Y GVYY+ SC + N+NH VL VGYG Sbjct: 122 LPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYGDL 180 Query: 287 KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 G ++W++KNSWG N+G +GYI MARNK N CGIA+ S+P++ Sbjct: 181 NGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 223 >4BS5-A nrPDB Length = 225 Score = 309 bits (791), Expect = 1e-84, Method: Composition-based stats. Identities = 129/222 (58%), Positives = 159/222 (71%), Gaps = 5/222 (2%) Query: 112 EGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV 171 PD+VD+R+KG VT VK QG CG+CWAFS+VGALEGQLK KTGKL++LS QNLVDC Sbjct: 5 NRTLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCS 64 Query: 172 S----ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREI 227 + N GCGGGYMT AFQY+ N GI+++ +YPY +E C YN +AA C Y ++ Sbjct: 65 NEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQL 124 Query: 228 PEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK 287 P G+E ALK AVA GPVSV IDAS +SF FY GVY D SC N+NH VL VGYG Sbjct: 125 PFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTG-NVNHGVLVVGYGTLD 183 Query: 288 GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 G +W++KNSWG N+G++GYI MARN N CGIA+ S+P++ Sbjct: 184 GKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 225 >2VHS-A nrPDB Length = 217 Score = 301 bits (772), Expect = 2e-82, Method: Composition-based stats. Identities = 128/218 (58%), Positives = 163/218 (74%), Gaps = 4/218 (1%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV--S 172 AP SVD+R+KGYVTPVKNQGQCG+ +AFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGASYAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDVGFVDIPK-QE 119 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG-IQKGNKH 291 KAL +AVA VGP+SVAIDA SF FY +G+Y+ C+S +LNHA+L VGYG I K+ Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFSSDCSSSSLNHAMLVVGYGFISNNQKY 179 Query: 292 WIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 180 WLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 217 >1S4V-A nrPDB Length = 229 Score = 299 bits (767), Expect = 8e-82, Method: Composition-based stats. Identities = 110/219 (50%), Positives = 141/219 (64%), Gaps = 9/219 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS-EN 174 P SVD+RKKG VT VK+QGQCGSCWAFS++ A+EG + KT KL++LS Q LVDC + +N Sbjct: 3 PASVDWRKKGAVTSVKDQGQCGSCWAFSTIVAVEGINQIKTNKLVSLSEQELVDCDTDQN 62 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCM-YNPTGKAAKCRGYREIPEGNEK 233 GC GG M AF+++++ GI +E YPY + +C A G+ +PE +E Sbjct: 63 QGCNGGLMDYAFEFIKQRGGITTEANYPYEAYDGTCDVSKENAPAVSIDGHENVPENDEN 122 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ-KGNKHW 292 AL +AVA PVSVAIDA + FQFYS+GV+ SC ++ L+H V VGYG G K+W Sbjct: 123 ALLKAVANQ-PVSVAIDAGGSDFQFYSEGVFTG-SCGTE-LDHGVAIVGYGTTIDGTKYW 179 Query: 293 IIKNSWGENWGNKGYILMARN---KNNACGIANLASFPK 328 +KNSWG WG KGYI M R K CGIA AS+P Sbjct: 180 TVKNSWGPEWGEKGYIRMERGISDKEGLCGIAMEASYPI 218 >1CQD-A nrPDB Length = 221 Score = 299 bits (766), Expect = 9e-82, Method: Composition-based stats. Identities = 102/217 (47%), Positives = 132/217 (60%), Gaps = 6/217 (2%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 PDS+D+R+ G V PVKNQG CGSCWAFS+V A+EG + TG L++LS Q LVDC + N Sbjct: 3 LPDSIDWRENGAVVPVKNQGGCGSCWAFSTVAAVEGINQIVTGDLISLSEQQLVDCTTAN 62 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC GG+M AFQ++ N GI+SE+ YPY GQ+ C Y +P NE++ Sbjct: 63 HGCRGGWMNPAFQFIVNNGGINSEETYPYRGQDGICNSTVNAPVVSIDSYENVPSHNEQS 122 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L++AVA PVSV +DA+ FQ Y G++ + NHA+ VGYG + WI+ Sbjct: 123 LQKAVANQ-PVSVTMDAAGRDFQLYRSGIFTGSCN--ISANHALTVVGYGTENDKDFWIV 179 Query: 295 KNSWGENWGNKGYILMARNKNNA---CGIANLASFPK 328 KNSWG+NWG GYI RN N CGI AS+P Sbjct: 180 KNSWGKNWGESGYIRAERNIENPDGKCGITRFASYPV 216 >2PNS-A nrPDB Length = 208 Score = 291 bits (745), Expect = 3e-79, Method: Composition-based stats. Identities = 100/215 (46%), Positives = 127/215 (59%), Gaps = 10/215 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P+ +D+RKKG VTPVKNQG+CGSCWAFS+V +E + +TG L++LS Q LVDC +N Sbjct: 1 LPEQIDWRKKGAVTPVKNQGKCGSCWAFSTVSTVESINQIRTGNLISLSEQQLVDCNKKN 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC GG A+QY+ N GID+E YPY + C K + GY+ +P NE A Sbjct: 61 HGCKGGAFVYAYQYIIDNGGIDTEANYPYKAVQGPCRA--AKKVVRIDGYKGVPHCNENA 118 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 LK+AVA P VAIDAS FQ Y G++ LNH V+ VGY +WI+ Sbjct: 119 LKKAVASQ-PSVVAIDASSKQFQHYKSGIFSGPC--GTKLNHGVVIVGY----WKDYWIV 171 Query: 295 KNSWGENWGNKGYILMAR-NKNNACGIANLASFPK 328 +NSWG WG +GYI M R CGIA L +P Sbjct: 172 RNSWGRYWGEQGYIRMKRVGGCGLCGIARLPYYPT 206 >2FO5-A nrPDB Length = 262 Score = 291 bits (745), Expect = 3e-79, Method: Composition-based stats. Identities = 101/223 (45%), Positives = 145/223 (65%), Gaps = 12/223 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS-E 173 P SVD+R+KG VT VK+QG+CGSCWAFS+V ++EG +TG L++LS Q L+DC + + Sbjct: 4 LPPSVDWRQKGAVTGVKDQGKCGSCWAFSTVVSVEGINAIRTGSLVSLSEQELIDCDTAD 63 Query: 174 NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGK----AAKCRGYREIPE 229 NDGC GG M NAF+Y++ N G+ +E AYPY +C + G++++P Sbjct: 64 NDGCQGGLMDNAFEYIKNNGGLITEAAYPYRAARGTCNVARAAQNSPVVVHIDGHQDVPA 123 Query: 230 GNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI-QKG 288 +E+ L RAVA PVSVA++AS +F FYS+GV+ E C ++ L+H V VGYG+ + G Sbjct: 124 NSEEDLARAVANQ-PVSVAVEASGKAFMFYSEGVFTGE-CGTE-LDHGVAVVGYGVAEDG 180 Query: 289 NKHWIIKNSWGENWGNKGYILMARN---KNNACGIANLASFPK 328 +W +KNSWG +WG +GYI + ++ CGIA AS+P Sbjct: 181 KAYWTVKNSWGPSWGEQGYIRVEKDSGASGGLCGIAMEASYPV 223 >3BCN-A nrPDB Length = 209 Score = 290 bits (743), Expect = 5e-79, Method: Composition-based stats. Identities = 98/215 (45%), Positives = 126/215 (58%), Gaps = 10/215 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P+ VD+R KG V P+KNQG+CGSCWAFS+V +E + +TG L++LS Q LVDC +N Sbjct: 1 LPEHVDWRAKGAVIPLKNQGKCGSCWAFSTVTTVESINQIRTGNLISLSEQQLVDCSKKN 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC GGY A+QY+ N GID+E YPY + C K + G + +P+ NE A Sbjct: 61 HGCKGGYFDRAYQYIIANGGIDTEANYPYKAFQGPCRA--AKKVVRIDGCKGVPQCNENA 118 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 LK AVA P VAIDAS FQ Y G++ LNH V+ VGYG +WI+ Sbjct: 119 LKNAVASQ-PSVVAIDASSKQFQHYKGGIFTGPC--GTKLNHGVVIVGYG----KDYWIV 171 Query: 295 KNSWGENWGNKGYILMAR-NKNNACGIANLASFPK 328 +NSWG +WG +GY M R CGIA L +P Sbjct: 172 RNSWGRHWGEQGYTRMKRVGGCGLCGIARLPFYPT 206 >1IWD-A nrPDB Length = 215 Score = 289 bits (741), Expect = 7e-79, Method: Composition-based stats. Identities = 103/217 (47%), Positives = 136/217 (62%), Gaps = 7/217 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P VD+R KG V +KNQ QCGSCWAFS+V A+E K +TG+L++LS Q LVDC + + Sbjct: 1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCDTAS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC GG+M NAFQY+ N GID++ YPY + SC + G++ + NE A Sbjct: 61 HGCNGGWMNNAFQYIITNGGIDTQQNYPYSAVQGSCKPYRL-RVVSINGFQRVTRNNESA 119 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 L+ AVA PVSV ++A+ FQ YS G++ C + NH V+ VGYG Q G +WI+ Sbjct: 120 LQSAVASQ-PVSVTVEAAGAPFQHYSSGIFTGP-CGTAQ-NHGVVIVGYGTQSGKNYWIV 176 Query: 295 KNSWGENWGNKGYILMARN---KNNACGIANLASFPK 328 +NSWG+NWGN+GYI M RN CGIA L S+P Sbjct: 177 RNSWGQNWGNQGYIWMERNVASSAGLCGIAQLPSYPT 213 >3P5W-A nrPDB Length = 220 Score = 289 bits (740), Expect = 1e-78, Method: Composition-based stats. Identities = 99/219 (45%), Positives = 132/219 (60%), Gaps = 8/219 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VS 172 PD VD+R G V +K+QGQCGSCWAFS++ A+EG K TG L++LS Q LVDC Sbjct: 1 LPDYVDWRSSGAVVDIKDQGQCGSCWAFSTIAAVEGINKIATGDLISLSEQELVDCGRTQ 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYREIPEGN 231 GC GG+MT+ FQ++ N GI++E YPY +E C + K Y +P N Sbjct: 61 NTRGCDGGFMTDGFQFIINNGGINTEANYPYTAEEGQCNLDLQQEKYVSIDTYENVPYNN 120 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E AL+ AVA PVSVA++A+ +FQ YS G++ ++HAV VGYG + G + Sbjct: 121 EWALQTAVAYQ-PVSVALEAAGYNFQHYSSGIFTGPC--GTAVDHAVTIVGYGTEGGIDY 177 Query: 292 WIIKNSWGENWGNKGYILMARNKN--NACGIANLASFPK 328 WI+KNSWG WG +GY+ + RN CGIA AS+P Sbjct: 178 WIVKNSWGTTWGEEGYMRIQRNVGGVGQCGIAKKASYPV 216 >4YYR-A nrPDB Length = 222 Score = 286 bits (732), Expect = 8e-78, Method: Composition-based stats. Identities = 98/220 (44%), Positives = 137/220 (62%), Gaps = 9/220 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS-- 172 P++VD+R +G V P++NQG+CGSCWAFS V +EG K T +L +LS Q LVDC + Sbjct: 1 LPETVDWRIQGAVNPIRNQGRCGSCWAFSVVVVVEGITKIVTDELPSLSEQQLVDCATSY 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYREIPEGN 231 +N GC GG+MT A+ Y+ KN GI S+ YPY ++ C + + A Y +P N Sbjct: 61 KNLGCSGGWMTKAYDYIIKNGGITSQSNYPYTAKKGECNKDLASQIVATIDSYEHVPRNN 120 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E ALK AVA PVSV I+A +F+ Y GV+ SC + L+HAV+A+GYG + + Sbjct: 121 ENALKNAVANQ-PVSVTIEAGGRAFELYKSGVFVG-SCGT-KLDHAVVAIGYGSENDVDY 177 Query: 292 WIIKNSWGENWGNKGYILMARN---KNNACGIANLASFPK 328 W+++NSWG NWG +GYI + RN CGIA +++P Sbjct: 178 WLVRNSWGTNWGERGYIKLQRNVAEPTGKCGIAMQSTYPV 217 >1XKG-A nrPDB Length = 312 Score = 286 bits (732), Expect = 9e-78, Method: Composition-based stats. Identities = 90/302 (29%), Positives = 136/302 (45%), Gaps = 20/302 (6%) Query: 20 EILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLG 79 +E +KK K Y DE + R + +++KY+ +++ G A+NHL Sbjct: 2 PSSIKTFEEYKKAFNKSYATFEDEEAARKNFLESVKYV-----QSNGG------AINHLS 50 Query: 80 DMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEW----EGRAPDSVDYRKKGYVTPVKNQGQ 135 D++ +E + H ++ L G AP +D R+ VTP++ QG Sbjct: 51 DLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTVTPIRMQGG 110 Query: 136 CGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGI 195 CGS WAFS V A E + L+L+ Q LVDC S+ GC G + +Y+Q N G+ Sbjct: 111 CGSAWAFSGVAATESAYLAYRDQSLDLAEQELVDCASQ-HGCHGDTIPRGIEYIQHN-GV 168 Query: 196 DSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDA--SL 253 E Y YV +E+SC P + Y +I N ++ A+A+ I L Sbjct: 169 VQESYYRYVAREQSCR-RPNAQRFGISNYCQIYPPNANKIREALAQTHSAIAVIIGIKDL 227 Query: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313 +F+ Y HAV VGY +G +WI++NSW NWG+ GY A N Sbjct: 228 DAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYGYFAAN 287 Query: 314 KN 315 + Sbjct: 288 ID 289 >1O0E-A nrPDB Length = 208 Score = 286 bits (731), Expect = 1e-77, Method: Composition-based stats. Identities = 101/215 (46%), Positives = 125/215 (58%), Gaps = 10/215 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P+ +D+RKKG VTPVKNQG CGSCWAFS+V +E + +TG L++LS Q LVDC +N Sbjct: 1 LPEQIDWRKKGAVTPVKNQGSCGSCWAFSTVSTVESINQIRTGNLISLSEQELVDCDKKN 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GC GG A+QY+ N GID++ YPY + C K GY +P NE A Sbjct: 61 HGCLGGAFVFAYQYIINNGGIDTQANYPYKAVQGPCQA--ASKVVSIDGYNGVPFCNEXA 118 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWII 294 LK+AVA P +VAIDAS FQ YS G++ LNH V VGY +WI+ Sbjct: 119 LKQAVAVQ-PSTVAIDASSAQFQQYSSGIFSGPC--GTKLNHGVTIVGYQAN----YWIV 171 Query: 295 KNSWGENWGNKGYILMAR-NKNNACGIANLASFPK 328 +NSWG WG KGYI M R CGIA L +P Sbjct: 172 RNSWGRYWGEKGYIRMLRVGGCGLCGIARLPYYPT 206 >5JT8-A nrPDB Length = 333 Score = 285 bits (730), Expect = 2e-77, Method: Composition-based stats. Identities = 95/321 (29%), Positives = 160/321 (49%), Gaps = 16/321 (4%) Query: 18 PEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNH 77 P +E +KK K Y N +E R +++ LK++ HN G+ E A+N Sbjct: 20 PTREEIKTFEQFKKVFGKVYRNAEEEARREHHFKEQLKWVEEHN-----GIDGVEYAINE 74 Query: 78 LGDMTSEEVVQKMTGLKVPLSHSRSNDTLY-IPEWEGRAPDSVDYRKKGYVTPVKNQGQC 136 DM+ +E ++G + ++ + + G P + D+R+K +T ++ QG C Sbjct: 75 YSDMSEQEFSFHLSGGGLNFTYMKMEAAKEPLINTYGSLPQNFDWRQKARLTRIRQQGSC 134 Query: 137 GSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC-------VSENDGCGGGYMTNAFQYV 189 GSCWAF++ G E + + + LS Q LVDC + +GCG GY T AF+Y+ Sbjct: 135 GSCWAFAAAGVAESLYSIQKQQSIELSEQELVDCTYNRYDPSYQCNGCGSGYSTEAFKYM 194 Query: 190 QKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREI-PEGNEKALKRAVARVGPVSVA 248 + G+ E YPY + + C + G+ GY+++ +++ + + + GPV + Sbjct: 195 IRT-GLVEERNYPYNMRTQWCDPDVEGQRYHVSGYQQLRYHSSDEDVMYTIQQHGPVVIY 253 Query: 249 IDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYI 308 + S F+ GV + N +HAV+ VG+G +G +WII+NSWG WGN GY Sbjct: 254 MHGSNNYFRNLGNGVLRGVAYNDAYTDHAVILVGWGTVQGVDYWIIRNSWGTGWGNGGYG 313 Query: 309 LMARNKNNACGIANLASFPKM 329 + R +N+ GI N ++ + Sbjct: 314 YVERG-HNSLGINNYVTYATL 333 >1NB3-A nrPDB Length = 220 Score = 284 bits (727), Expect = 3e-77, Method: Composition-based stats. Identities = 106/219 (48%), Positives = 138/219 (63%), Gaps = 7/219 (3%) Query: 115 APDSVDYRKKG-YVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE 173 P S+D+RKKG +V+PVKNQG CGSCW FS+ GALE + TGK+L+L+ Q LVDC Sbjct: 1 YPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQN 60 Query: 174 --NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGN 231 N GC GG + AF+Y++ N+GI ED YPY GQ++ C + P A + I + Sbjct: 61 FNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMND 120 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCN--SDNLNHAVLAVGYGIQKGN 289 E+A+ AVA PVS A + + F Y KG+Y SC+ D +NHAVLAVGYG + G Sbjct: 121 EEAMVEAVALYNPVSFAFEVT-NDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGI 179 Query: 290 KHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPK 328 +WI+KNSWG WG GY L+ R K N CG+A AS+P Sbjct: 180 PYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAACASYPI 217 >3F75-A nrPDB Length = 224 Score = 284 bits (726), Expect = 5e-77, Method: Composition-based stats. Identities = 109/222 (49%), Positives = 141/222 (63%), Gaps = 9/222 (4%) Query: 114 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS- 172 P VD+R +G VTPVK+Q CGSCWAFS+ GALEG KTGKL++LS Q L+DC Sbjct: 6 ELPAGVDWRSRGCVTPVKDQRDCGSCWAFSTTGALEGAHCAKTGKLVSLSEQELMDCSRA 65 Query: 173 -ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGN 231 N C GG M +AFQYV + GI SEDAYPY+ ++E C K K G++++P + Sbjct: 66 EGNQSCSGGEMNDAFQYVLDSGGICSEDAYPYLARDEECRAQSCEKVVKILGFKDVPRRS 125 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI--QKGN 289 E A+K A+A+ PVS+AI+A FQFY +GV+ D SC +D L+H VL VGYG + Sbjct: 126 EAAMKAALAK-SPVSIAIEADQMPFQFYHEGVF-DASCGTD-LDHGVLLVGYGTDKESKK 182 Query: 290 KHWIIKNSWGENWGNKGYILMA--RNKNNACGIANLASFPKM 329 WI+KNSWG WG GY+ MA + + CG+ ASFP M Sbjct: 183 DFWIMKNSWGTGWGRDGYMYMAMHKGEEGQCGLLLDASFPVM 224 >1AEC-A nrPDB Length = 218 Score = 281 bits (718), Expect = 3e-76, Method: Composition-based stats. Identities = 92/219 (42%), Positives = 129/219 (58%), Gaps = 8/219 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VS 172 P VD+R G V +K+QG+CG CWAFS++ +EG K TG L++LS Q L+DC Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQ 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYREIPEGN 231 GC GGY+T+ FQ++ N GI++E+ YPY Q+ C + K Y +P N Sbjct: 61 NTRGCNGGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNN 120 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E AL+ AV PVSVA+DA+ +F+ YS G++ ++HAV VGYG + G + Sbjct: 121 EWALQTAVTYQ-PVSVALDAAGDAFKQYSSGIFTGPC--GTAIDHAVTIVGYGTEGGIDY 177 Query: 292 WIIKNSWGENWGNKGYILMARNKNNA--CGIANLASFPK 328 WI+KNSW WG +GY+ + RN A CGIA + S+P Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >4YYW-A nrPDB Length = 220 Score = 278 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 96/220 (43%), Positives = 137/220 (62%), Gaps = 9/220 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS-- 172 P++VD+R KG V P+++QG+CGSCW FS +EG +K T L +LS Q L+DC Sbjct: 1 LPETVDWRSKGAVDPIRDQGKCGSCWVFSVTVVVEGIVKIVTDTLPSLSEQELLDCAPSY 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP-TGKAAKCRGYREIPEGN 231 ++ GC GG+M A+ Y+ K+RGI SE YPY ++ +C T A Y ++P N Sbjct: 61 KDLGCKGGWMDKAYDYIIKDRGITSESDYPYTARKGACDSRKATEVVATISSYEDVPADN 120 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E ALK+AVA PVSVAIDAS + + YS GV+ SC N +HAV+ VGYG + G + Sbjct: 121 EDALKKAVANQ-PVSVAIDASSAAVKEYSSGVFVG-SCGVAN-DHAVVVVGYGTESGVNY 177 Query: 292 WIIKNSWGENWGNKGYILMARNKNNA---CGIANLASFPK 328 W+++NSWG WG +GY+ + R+ + CGIA +++P Sbjct: 178 WLVRNSWGTKWGEEGYMKLERDTAHPAGKCGIAMESTYPV 217 >3PDF-A nrPDB Length = 441 Score = 278 bits (710), Expect = 3e-75, Method: Composition-based stats. Identities = 91/312 (29%), Positives = 144/312 (46%), Gaps = 32/312 (10%) Query: 31 KTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTY-ELAMNHLGDMT--SEEVV 87 K +++Y+N++ + + +I+ ++ S TY E LGDM S Sbjct: 133 KNSQEKYSNRLYKYDHNFV-------KAINAIQKSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 88 QKMTGLK-VPLSHSRSNDTLYIP-EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSV 145 +K+ K PL+ L++P W+ R ++ +V+PV+NQ CGSC++F+S+ Sbjct: 186 RKIPRPKPAPLTAEIQQKILFLPTSWDWRNVHGIN-----FVSPVRNQASCGSCYSFASM 240 Query: 146 GALEGQLKKKTG--KLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPY 203 G LE +++ T + LSPQ +V C GC GG+ ++ G+ E +PY Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY 300 Query: 204 VGQEESCMYNPTGKAAKCRGYREI----PEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259 G + C Y + NE +K + GP++VA + F Y Sbjct: 301 TGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHY 359 Query: 260 SKGVYY-----DESCNSDNLNHAVLAVGYGIQ--KGNKHWIIKNSWGENWGNKGYILMAR 312 KG+Y+ D + NHAVL VGYG G +WI+KNSWG WG GY + R Sbjct: 360 KKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRR 419 Query: 313 NKNNACGIANLA 324 + C I ++A Sbjct: 420 GTD-ECAIESIA 430 >1YAL-A nrPDB Length = 218 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 98/217 (45%), Positives = 127/217 (58%), Gaps = 8/217 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P S+D+R KG VTPVKNQG CGSCWAFS++ +EG K TG LL LS Q LVDC + Sbjct: 1 YPQSIDWRAKGAVTPVKNQGACGSCWAFSTIATVEGINKIVTGNLLELSEQELVDCDKHS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCM-YNPTGKAAKCRGYREIPEGNEK 233 GC GGY T + QYV N G+ + YPY ++ C + G K GY+ +P E Sbjct: 61 YGCKGGYQTTSLQYVANN-GVHTSKVYPYQAKQYKCRATDKPGPKVKITGYKRVPSNCET 119 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWI 293 + A+A P+SV ++A FQ Y GV+ D C + L+HAV AVGYG G + I Sbjct: 120 SFLGALANQ-PLSVLVEAGGKPFQLYKSGVF-DGPCGT-KLDHAVTAVGYGTSDGKNYII 176 Query: 294 IKNSWGENWGNKGYILMARNKNNA---CGIANLASFP 327 IKNSWG NWG KGY+ + R N+ CG+ + +P Sbjct: 177 IKNSWGPNWGEKGYMRLKRQSGNSQGTCGVYKSSYYP 213 >2ACT-A nrPDB Length = 220 Score = 274 bits (701), Expect = 3e-74, Method: Composition-based stats. Identities = 88/219 (40%), Positives = 129/219 (58%), Gaps = 8/219 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VS 172 P VD+R G V +K+QG+CG CWAFS++ +EG K +G L++LS Q L+DC Sbjct: 1 LPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKITSGSLISLSEQELIDCGRTQ 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYREIPEGN 231 GC GGY+T+ FQ++ + GI++E+ YPY Q+ C K Y +P N Sbjct: 61 NTRGCDGGYITDGFQFIINDGGINTEENYPYTAQDGDCDVALQDQKYVTIDTYENVPYNN 120 Query: 232 EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKH 291 E AL+ AV PVSVA+DA+ +F+ Y+ G++ ++HA++ VGYG + G + Sbjct: 121 EWALQTAVTYQ-PVSVALDAAGDAFKQYASGIFTGPC--GTAVDHAIVIVGYGTEGGVDY 177 Query: 292 WIIKNSWGENWGNKGYILMARNKNNA--CGIANLASFPK 328 WI+KNSW WG +GY+ + RN A CGIA + S+P Sbjct: 178 WIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPV 216 >2BDZ-A nrPDB Length = 214 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 95/218 (43%), Positives = 127/218 (58%), Gaps = 12/218 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P+S+D+R+KG VTPVKNQ CGSCWAFS+V +EG K TG+L++LS Q L+DC + Sbjct: 1 YPESIDWREKGAVTPVKNQNPCGSCWAFSTVATIEGINKIITGQLISLSEQELLDCERRS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMY-NPTGKAAKCRGYREIPEGNEK 233 GC GGY T + QYV N G+ +E YPY ++ C + G GY+ +P +E Sbjct: 61 HGCDGGYQTTSLQYVVDN-GVHTEREYPYEKKQGRCRAKDKKGPKVYITGYKYVPANDEI 119 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWI 293 +L +A+A PVSV D+ FQFY G+Y N +HAV AVGYG + + Sbjct: 120 SLIQAIANQ-PVSVVTDSRGRGFQFYKGGIYEGPC--GTNTDHAVTAVGYGKT----YLL 172 Query: 294 IKNSWGENWGNKGYILMARNKN---NACGIANLASFPK 328 +KNSWG NWG KGYI + R CG+ + FP Sbjct: 173 LKNSWGPNWGEKGYIRIKRASGRSKGTCGVYTSSFFPI 210 >1PPO-A nrPDB Length = 216 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 94/218 (43%), Positives = 125/218 (57%), Gaps = 8/218 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P++VD+RKKG VTPV++QG CGSCWAFS+V +EG K +TGKL+ LS Q LVDC + Sbjct: 1 LPENVDWRKKGAVTPVRHQGSCGSCWAFSAVATVEGINKIRTGKLVELSEQELVDCERRS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEK 233 GC GGY A +YV KN GI YPY ++ +C G K G + NE Sbjct: 61 HGCKGGYPPYALEYVAKN-GIHLRSKYPYKAKQGTCRAKQVGGPIVKTSGVGRVQPNNEG 119 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWI 293 L A+A+ PVSV +++ FQ Y G++ ++HAV AVGYG G + + Sbjct: 120 NLLNAIAKQ-PVSVVVESKGRPFQLYKGGIFEGPC--GTKVDHAVTAVGYGKSGGKGYIL 176 Query: 294 IKNSWGENWGNKGYILMARNKNNA---CGIANLASFPK 328 IKNSWG WG KGYI + R N+ CG+ + +P Sbjct: 177 IKNSWGTAWGEKGYIRIKRAPGNSPGVCGLYKSSYYPT 214 >6MIS-A nrPDB Length = 215 Score = 264 bits (675), Expect = 4e-71, Method: Composition-based stats. Identities = 86/218 (39%), Positives = 126/218 (57%), Gaps = 9/218 (4%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P S+D+R G VT VKNQG+CGSCWAF+S+ +E K K G L++LS Q ++DC + Sbjct: 2 PQSIDWRDSGAVTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVSLSEQQVLDCAV-SY 60 Query: 176 GCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKAL 235 GC GG++ A+ ++ N+G+ S YPY + +C N +A Y + NE+ + Sbjct: 61 GCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYVQRNNERNM 120 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG-IQKGNKHWII 294 AV+ P++ A+DAS FQ Y +GV+ LNHA++ +GYG G K WI+ Sbjct: 121 MYAVSNQ-PIAAALDASGN-FQHYKRGVFTGPC--GTRLNHAIVIIGYGQDSSGKKFWIV 176 Query: 295 KNSWGENWGNKGYILMARNKN---NACGIANLASFPKM 329 +NSWG WG GYI +AR+ + CGIA +P + Sbjct: 177 RNSWGAGWGEGGYIRLARDVSSSFGLCGIAMDPLYPTL 214 >2CIO-A nrPDB Length = 212 Score = 262 bits (670), Expect = 1e-70, Method: Composition-based stats. Identities = 94/218 (43%), Positives = 125/218 (57%), Gaps = 12/218 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P+ VD+R+KG VTPVKNQG CGSCWAFS+V +EG +K +TG L S Q L+DC + Sbjct: 1 IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSEQELLDCDRRS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGK-AAKCRGYREIPEGNEK 233 GC GGY +A Q V + GI + YPY G + C G AAK G R++ NE Sbjct: 61 YGCNGGYPWSALQLVAQ-YGIHYRNTYPYEGVQRYCRSREKGPYAAKTDGVRQVQPYNEG 119 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWI 293 AL ++A PVSV ++A+ FQ Y G++ N ++HAV AVGYG + + Sbjct: 120 ALLYSIANQ-PVSVVLEAAGKDFQLYRGGIFVGPCGN--KVDHAVAAVGYG----PNYIL 172 Query: 294 IKNSWGENWGNKGYILMARNKNNA---CGIANLASFPK 328 IKNSWG WG GYI + R N+ CG+ + +P Sbjct: 173 IKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPV 210 >5A24-A nrPDB Length = 222 Score = 262 bits (669), Expect = 2e-70, Method: Composition-based stats. Identities = 110/223 (49%), Positives = 138/223 (61%), Gaps = 13/223 (5%) Query: 116 PDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND 175 P +VD+R G VTPVKNQ QCG CWAFS+V A+EG + KTG L +LS + +VDC + + Sbjct: 2 PAAVDWRTAGAVTPVKNQQQCGCCWAFSAVAAIEGATQIKTGTLTSLSEEQIVDCDTNGN 61 Query: 176 --GCGGGYMTNAFQYVQKNRGIDSEDAYPYV---GQEESCMYNPTGKAAKCRGYREIPEG 230 GC GG AFQYV N+GID+E YPY G +C + AA GY+++P Sbjct: 62 DKGCNGGTPDGAFQYVVNNQGIDTESDYPYTAGGGSPGTCSASSYQPAASITGYQDVPAN 121 Query: 231 NEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGI--QKG 288 NE+AL++A A P+SVAIDAS SFQ YS G+Y NL+HAV VGYG G Sbjct: 122 NEQALQQA-AATQPISVAIDASDPSFQSYSSGIYSGPCN--TNLDHAVTVVGYGTDPNSG 178 Query: 289 NKHWIIKNSWGENWGNKGYILMARNKN---NACGIANLASFPK 328 N +WI+KNSWG +WG +GYI M N CGIA AS+P Sbjct: 179 NSYWIVKNSWGTSWGQEGYIWMQMGLNAPYGVCGIAMQASYPT 221 >1MIR-A nrPDB Length = 322 Score = 260 bits (664), Expect = 7e-70, Method: Composition-based stats. Identities = 83/331 (25%), Positives = 141/331 (42%), Gaps = 62/331 (18%) Query: 42 DEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSR 101 D+ S + + + YI+ N G + Y + +++L + + G K+P Sbjct: 2 DKPSFHPLSDDMINYINKQNTTWQAGRNFYNVDISYLKKLCG----TVLGGPKLPERVGF 57 Query: 102 SNDTLYIPEWEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTG 157 S D P+S D R++ P +++QG CGS WAF +V A+ ++ T Sbjct: 58 SEDI--------NLPESFDAREQWSNCPTIAQIRDQGSCGSSWAFGAVEAMSDRICIHTN 109 Query: 158 KLLNL--SPQNLVDCV--SENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQ 206 +N+ S ++L+ C DGC GGY + A+ + + +G+ S Y PY Sbjct: 110 GRVNVEVSAEDLLTCCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYT-- 166 Query: 207 EESCMYNPTGKAAKCRGYREIPEGN---------------------------EKALKRAV 239 C ++ G C G + P+ N EK + + Sbjct: 167 IPPCEHHVNGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEI 226 Query: 240 ARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWG 299 + GPV A + F Y GVY E+ HA+ +G+GI+ G +W++ NSW Sbjct: 227 YKNGPVEGAFTV-FSDFLTYKSGVYKHEA-GDVMGGHAIRILGWGIENGVPYWLVANSWN 284 Query: 300 ENWGNKGYILMARNKNNACGIAN--LASFPK 328 +WG+ G+ + R + N CGI + +A P+ Sbjct: 285 ADWGDNGFFKILRGE-NHCGIESEIVAGIPR 314 >4YYQ-A nrPDB Length = 217 Score = 259 bits (663), Expect = 8e-70, Method: Composition-based stats. Identities = 100/219 (45%), Positives = 138/219 (63%), Gaps = 9/219 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS-- 172 P++VD+R KG V P++NQGQCGSCWAFS+V A+E K TG+LL+LS Q L+DC Sbjct: 1 LPETVDWRSKGAVNPIRNQGQCGSCWAFSAVAAVESINKIVTGQLLSLSEQQLLDCAQSY 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 +N GC GG++ AF+Y+ +NRGI S+ YPY G + C A Y+ +P NE Sbjct: 61 KNLGCQGGWVNKAFEYIIQNRGITSQSNYPYTGHKGQCRT-GLASIATIDSYQYVPSNNE 119 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHW 292 ALK AVA PVSVA++A+ +FQ Y GV+ SC ++HAV+ +GYG G +W Sbjct: 120 NALKNAVANQ-PVSVAVEAAGRAFQLYKSGVFTG-SCGVA-IDHAVVLIGYGKYNGVDYW 176 Query: 293 IIKNSWGENWGNKGYILMARN---KNNACGIANLASFPK 328 +++NSWG NWG +GY+ + RN CG+A L +P Sbjct: 177 LLRNSWGTNWGEQGYMKLQRNVAQSAGKCGVARLCLYPV 215 >1ICF-A nrPDB Length = 175 Score = 258 bits (660), Expect = 2e-69, Method: Composition-based stats. Identities = 106/175 (60%), Positives = 133/175 (76%), Gaps = 3/175 (1%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV--S 172 AP SVD+R+KGYVTPVKNQGQCGSCWAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQ 60 Query: 173 ENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNE 232 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP A G+ +IP+ E Sbjct: 61 GNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QE 119 Query: 233 KALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK 287 KAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VGYG + Sbjct: 120 KALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFES 174 >3U8E-A nrPDB Length = 222 Score = 257 bits (657), Expect = 5e-69, Method: Composition-based stats. Identities = 100/221 (45%), Positives = 131/221 (59%), Gaps = 10/221 (4%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP S+D+RKKG VT VK+QG CG CWAF + GA+EG TG+L+++S Q +VDC + Sbjct: 1 APASIDWRKKGAVTSVKDQGACGMCWAFGATGAIEGIDAITTGRLISVSEQQIVDCDTXX 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 GG +AF++V N GI S+ YPY G + +C N AA+ GY +P + A Sbjct: 61 XXXXGGDADDAFRWVITNGGIASDANYPYTGVDGTCDLNK-PIAARIDGYTNVP-NSSSA 118 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSK-GVYYDESCNSDN--LNHAVLAVGYGIQKGN-K 290 L AVA+ PVSV I S TSFQ Y+ G++ SC+ D ++H VL VGYG N Sbjct: 119 LLDAVAKQ-PVSVNIYTSSTSFQLYTGPGIFAGSSCSDDPATVDHTVLIVGYGSNGTNAD 177 Query: 291 HWIIKNSWGENWGNKGYILMARNKN---NACGIANLASFPK 328 +WI+KNSWG WG GYIL+ RN N C I S+P Sbjct: 178 YWIVKNSWGTEWGIDGYILIRRNTNRPDGVCAIDAWGSYPT 218 >2B1M-A nrPDB Length = 246 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 96/225 (42%), Positives = 130/225 (57%), Gaps = 12/225 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP+S D+ KKG +T VK QGQCGS WAFS+ GA+E TG L++LS Q L+DCV E+ Sbjct: 2 APESWDWSKKGVITKVKFQGQCGSGWAFSATGAIEAAHAIATGNLVSLSEQELIDCVDES 61 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYR------EIP 228 +GC G+ +F++V K+ GI SE YPY ++ C N Y E Sbjct: 62 EGCYNGWHYQSFEWVVKHGGIASEADYPYKARDGKCKANEIQDKVTIDNYGVQILSNEST 121 Query: 229 EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN-LNHAVLAVGYGIQK 287 E ++ ++ P+SV+IDA F FYS G+Y +C+S +NH VL VGYG + Sbjct: 122 ESEAESSLQSFVLEQPISVSIDA--KDFHFYSGGIYDGGNCSSPYGINHFVLIVGYGSED 179 Query: 288 GNKHWIIKNSWGENWGNKGYILMARNKNN---ACGIANLASFPKM 329 G +WI KNSWGE+WG GYI + RN N CG+ AS+P + Sbjct: 180 GVDYWIAKNSWGEDWGIDGYIRIQRNTGNLLGVCGMNYFASYPII 224 >1GEC-E nrPDB Length = 216 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 94/218 (43%), Positives = 130/218 (59%), Gaps = 8/218 (3%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P+SVD+R KG VTPVK+QG C SCWAFS+V +EG K KTG L+ LS Q LVDC ++ Sbjct: 1 LPESVDWRAKGAVTPVKHQGYCESCWAFSTVATVEGINKIKTGNLVELSEQELVDCDLQS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPT-GKAAKCRGYREIPEGNEK 233 GC GY + + QYV +N GI YPY+ ++++C N G K G + NE Sbjct: 61 YGCNRGYQSTSLQYVAQN-GIHLRAKYPYIAKQQTCRANQVGGPKVKTNGVGRVQSNNEG 119 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWI 293 +L A+A PVSV ++++ FQ Y G++ + SC + ++HAV AVGYG G + + Sbjct: 120 SLLNAIAHQ-PVSVVVESAGRDFQNYKGGIF-EGSCGT-KVDHAVTAVGYGKSGGKGYIL 176 Query: 294 IKNSWGENWGNKGYILMARNKNNA---CGIANLASFPK 328 IKNSWG WG GYI + R N+ CG+ + +P Sbjct: 177 IKNSWGPGWGENGYIRIRRASGNSPGVCGVYRSSYYPI 214 >3PBH-A nrPDB Length = 317 Score = 251 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 77/330 (23%), Positives = 138/330 (41%), Gaps = 62/330 (18%) Query: 43 EISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRS 102 S + ++ + Y++ N G + Y + M++L + + G K P + Sbjct: 4 RPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG----TFLGGPKPPQRVMFT 59 Query: 103 NDTLYIPEWEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGK 158 D + P S D R++ P +++QG CGSCWAF +V A+ ++ T Sbjct: 60 EDL--------KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNA 111 Query: 159 LLNL--SPQNLVDCVS--ENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQE 207 +++ S ++L+ C DGC GGY A+ + + +G+ S Y PY Sbjct: 112 HVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPY--SI 168 Query: 208 ESCMYNPTGKAAKCRGYREIPEGN---------------------------EKALKRAVA 240 C ++ G C G + P+ + EK + + Sbjct: 169 PPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIY 228 Query: 241 RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE 300 + GPV A + F Y GVY + HA+ +G+G++ G +W++ NSW Sbjct: 229 KNGPVEGAFSV-YSDFLLYKSGVYQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNT 286 Query: 301 NWGNKGYILMARNKNNACGIAN--LASFPK 328 +WG+ G+ + R ++ CGI + +A P+ Sbjct: 287 DWGDNGFFKILRGQD-HCGIESEVVAGIPR 315 >1JQP-A nrPDB Length = 438 Score = 249 bits (636), Expect = 1e-66, Method: Composition-based stats. Identities = 80/308 (25%), Positives = 136/308 (44%), Gaps = 31/308 (10%) Query: 34 RKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYE-LAMNHLGDMTS-EEVVQKMT 91 +++Y+ ++ + +I++++ S TY + D+ ++ Sbjct: 136 QEKYSERLYSHHHNFV-------KAINSVQKSWTATTYRRYEKLSIRDLIRRSGHSGRIL 188 Query: 92 GLK-VPLSHSRSNDTLYIPE-WEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALE 149 K P++ L +PE W+ R ++ +V+PV+NQ CGSC++F+S+G LE Sbjct: 189 RPKPAPITDEIQQQILSLPESWDWRNVRGIN-----FVSPVRNQESCGSCYSFASLGMLE 243 Query: 150 GQLKKKTG--KLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQE 207 +++ T + LSPQ +V C GC GG+ ++ G+ E+ +PY + Sbjct: 244 ARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATD 303 Query: 208 ESCMYNPTGKAAKCRG----YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGV 263 C NE +K + + GP++VA + F Y G+ Sbjct: 304 APCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVAFEV-HDDFLHYHSGI 362 Query: 264 YY-----DESCNSDNLNHAVLAVGYGIQ--KGNKHWIIKNSWGENWGNKGYILMARNKNN 316 Y+ D + NHAVL VGYG G +WI+KNSWG WG GY + R + Sbjct: 363 YHHTGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTD- 421 Query: 317 ACGIANLA 324 C I ++A Sbjct: 422 ECAIESIA 429 >6EXO-A nrPDB Length = 215 Score = 247 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 91/216 (42%), Positives = 131/216 (60%), Gaps = 11/216 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP +VD+R+KG VTPVK+QGQCGSCWAFS++G +EGQ + L++LS Q LV C + + Sbjct: 1 APAAVDWREKGAVTPVKDQGQCGSCWAFSTIGNIEGQWQVAGNPLVSLSEQMLVSCDTID 60 Query: 175 DGCGGGYMTNAFQYVQKNRG--IDSEDAYPYV---GQEESCMYNPTGKAAKCRGYREIPE 229 GCGGG M NAF ++ + G + +E +YPYV G++ C N A + ++P+ Sbjct: 61 FGCGGGLMDNAFNWIVNSNGGNVFTEASYPYVSGNGEQPQCQMNGHEIGAAITDHVDLPQ 120 Query: 230 GNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN 289 +E A+ +A GP+++A+DA+ SF Y+ G+ SC S+ L+H VL VGY Sbjct: 121 -DEDAIAAYLAENGPLAIAVDAT--SFMDYNGGIL--TSCTSEQLDHGVLLVGYNDASNP 175 Query: 290 KHWIIKNSWGENWGNKGYILMARNKNNACGIANLAS 325 +WIIKNSW WG GYI + + N C + S Sbjct: 176 PYWIIKNSWSNMWGEDGYIRIEKGT-NQCLMNQAVS 210 >3IOQ-A nrPDB Length = 213 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 96/218 (44%), Positives = 127/218 (58%), Gaps = 12/218 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 P S+D+R+KG VTPV+NQG CGSCW FSSV A+EG K TG+LL+LS Q L+DC + Sbjct: 1 IPTSIDWRQKGAVTPVRNQGGCGSCWTFSSVAAVEGINKIVTGQLLSLSEQELLDCERRS 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP-TGKAAKCRGYREIPEGNEK 233 GC GG+ A QYV N GI YPY G + C + G K G +P NE+ Sbjct: 61 YGCRGGFPLYALQYVA-NSGIHLRQYYPYEGVQRQCRASQAKGPKVKTDGVGRVPRNNEQ 119 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWI 293 AL + +A PVS+ ++A +FQ Y G++ +++HAV AVGYG N + + Sbjct: 120 ALIQRIAIQ-PVSIVVEAKGRAFQNYRGGIFAGPC--GTSIDHAVAAVGYG----NDYIL 172 Query: 294 IKNSWGENWGNKGYILMARNKNN---ACGIANLASFPK 328 IKNSWG WG GYI + R N ACG+ + + FP Sbjct: 173 IKNSWGTGWGEGGYIRIKRGSGNPQGACGVLSDSVFPT 210 >3BPF-A nrPDB Length = 241 Score = 241 bits (614), Expect = 4e-64, Method: Composition-based stats. Identities = 82/227 (36%), Positives = 127/227 (55%), Gaps = 20/227 (8%) Query: 117 DSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDG 176 + D+R VTPVK+Q CGSCWAFSS+G++E Q + KL+ LS Q LVDC +N G Sbjct: 20 AAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYG 79 Query: 177 CGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEES-CMYNPTGKAAKCRGYREIPEGNEKAL 235 C GG + NAF+ + + GI + YPYV + C + + + Y +P + L Sbjct: 80 CNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVP---DNKL 136 Query: 236 KRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNK----- 290 K A+ +GP+S+++ S F FY +G++ E D LNHAV+ VG+G+++ Sbjct: 137 KEALRFLGPISISVAVS-DDFAFYKEGIFDGEC--GDQLNHAVMLVGFGMKEIVNPLTKK 193 Query: 291 -----HWIIKNSWGENWGNKGYILMARNKNN---ACGIANLASFPKM 329 ++IIKNSWG+ WG +G+I + +++ CG+ A P + Sbjct: 194 GEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLI 240 >4PI3-A nrPDB Length = 216 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 93/216 (43%), Positives = 127/216 (58%), Gaps = 11/216 (5%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP +VD+R +G VT VK+QGQCGSCWAFS++G +E Q L NLS Q LV C + Sbjct: 2 APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTD 61 Query: 175 DGCGGGYMTNAFQYVQK--NRGIDSEDAYPY---VGQEESCMYNPTGKAAKCRGYREIPE 229 GC GG M NAF+++ + N + +ED+YPY G C + A G+ E+P+ Sbjct: 62 SGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQ 121 Query: 230 GNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN 289 +E + +A GPV+VA+DAS S+ Y+ GV SC S+ L+H VL VGY Sbjct: 122 -DEAQIAAWLAVNGPVAVAVDAS--SWMTYTGGVM--TSCVSEQLDHGVLLVGYNDSAAV 176 Query: 290 KHWIIKNSWGENWGNKGYILMARNKNNACGIANLAS 325 +WIIKNSW WG +GYI +A+ +N C + AS Sbjct: 177 PYWIIKNSWTTQWGEEGYIRIAKG-SNQCLVKEEAS 211 >5VPK-A nrPDB Length = 223 Score = 234 bits (598), Expect = 3e-62, Method: Composition-based stats. Identities = 70/207 (33%), Positives = 96/207 (46%), Gaps = 5/207 (2%) Query: 111 WEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC 170 P +D R VTP++ QG CGSCWAFS V A E L+LS Q LVDC Sbjct: 7 NSVNVPSELDLRSLRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNTSLDLSEQELVDC 66 Query: 171 VSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEG 230 S+ GC G + +Y+Q+N G+ E +YPYV +E+ C P + Y +I Sbjct: 67 ASQ-HGCHGDTIPRGIEYIQQN-GVVEERSYPYVAREQQCR-RPNSQHYGISNYCQIYPP 123 Query: 231 NEKALKRAVARVGPVSVAIDA--SLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKG 288 + K ++ A+ + I L +FQ Y HAV VGYG +G Sbjct: 124 DVKQIREALTQTHTAIAVIIGIKDLRAFQHYDGRTIIQHDNGYQPNYHAVNIVGYGSTQG 183 Query: 289 NKHWIIKNSWGENWGNKGYILMARNKN 315 +WI++NSW WG+ GY N Sbjct: 184 VDYWIVRNSWDTTWGDSGYGYFQAGNN 210 >3BPM-A nrPDB Length = 243 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 91/226 (40%), Positives = 123/226 (54%), Gaps = 20/226 (8%) Query: 118 SVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGC 177 + D+R G VTPVK+Q CGSCWAFSSVG++E Q + L S Q LVDC +N+GC Sbjct: 23 AYDWRLHGGVTPVKDQALCGSCWAFSSVGSVESQYAIRKKALFLFSEQELVDCSVKNNGC 82 Query: 178 GGGYMTNAFQYVQKNRGIDSEDAYPYVGQ-EESCMYNPTGKAAKCRGYREIPEGNEKALK 236 GGY+TNAF + G+ S+D YPYV E+C + + Y IP + K Sbjct: 83 YGGYITNAFDDMIDLGGLCSQDDYPYVSNLPETCNLKRCNERYTIKSYVSIP---DDKFK 139 Query: 237 RAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK--------- 287 A+ +GP+S++I AS F FY G Y D C + NHAV+ VGYG++ Sbjct: 140 EALRYLGPISISIAAS-DDFAFYRGGFY-DGECGAAP-NHAVILVGYGMKDIYNEDTGRM 196 Query: 288 -GNKHWIIKNSWGENWGNKGYILMARNKNN---ACGIANLASFPKM 329 ++IIKNSWG +WG GYI + ++N C I A P + Sbjct: 197 EKFYYYIIKNSWGSDWGEGGYINLETDENGYKKTCSIGTEAYVPLL 242 >5VCN-A nrPDB Length = 222 Score = 233 bits (595), Expect = 8e-62, Method: Composition-based stats. Identities = 72/208 (34%), Positives = 100/208 (48%), Gaps = 5/208 (2%) Query: 110 EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVD 169 G AP +D R+ VTP++ QG CGSCWAFS V A E + L+L+ Q LVD Sbjct: 5 SINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVD 64 Query: 170 CVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPE 229 C S+ GC G + +Y+Q N G+ E Y YV +E+SC P + Y +I Sbjct: 65 CASQ-HGCHGDTIPRGIEYIQHN-GVVQESYYRYVAREQSCR-RPNAQRFGISNYCQIYP 121 Query: 230 GNEKALKRAVARVGPVSVAIDA--SLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQK 287 N ++ A+A+ I L +F+ Y HAV VGY + Sbjct: 122 PNANKIREALAQTHSAIAVIIGIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQ 181 Query: 288 GNKHWIIKNSWGENWGNKGYILMARNKN 315 G +WI++NSW NWG+ GY A N + Sbjct: 182 GVDYWIVRNSWDTNWGDNGYGYFAANID 209 >1CPJ-A nrPDB Length = 260 Score = 223 bits (568), Expect = 9e-59, Method: Composition-based stats. Identities = 71/263 (26%), Positives = 117/263 (44%), Gaps = 50/263 (19%) Query: 110 EWEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNL--S 163 + P+S D R++ P +++QG CGSCWAF +V A+ ++ T +N+ S Sbjct: 2 SEDINLPESFDAREQWSNCPTIAQIRDQGSCGSCWAFGAVEAMSDRICIHTNGRVNVEVS 61 Query: 164 PQNLVDCV--SENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQEESCMYNP 214 ++L+ C DGC GGY + A+ + + +G+ S Y PY C ++ Sbjct: 62 AEDLLTCCGIQCGDGCNGGYPSGAWNFWTR-KGLVSGGVYNSHIGCLPYT--IPPCEHHV 118 Query: 215 TGKAAKCRGYREIPEGN---------------------------EKALKRAVARVGPVSV 247 G C G + P+ N EK + + + GPV Sbjct: 119 NGARPPCTGEGDTPKCNKMCEAGYSTSYKEDKHYGYTSYSVSDSEKEIMAEIYKNGPVEG 178 Query: 248 AIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGY 307 A + F Y GVY E+ HA+ +G+GI+ G +W++ NSW +WG+ G+ Sbjct: 179 AFTV-FSDFLTYKSGVYKHEA-GDVMGGHAIRILGWGIENGVPYWLVANSWNADWGDNGF 236 Query: 308 ILMARNKNNACGIAN--LASFPK 328 + R + N CGI + +A P+ Sbjct: 237 FKILRGE-NHCGIESEIVAGIPR 258 >1M6D-A nrPDB Length = 214 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 89/213 (41%), Positives = 123/213 (57%), Gaps = 6/213 (2%) Query: 115 APDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN 174 AP D+R KG VT VK+QG CGSCWAFS G +EGQ G LL+LS Q L+DC + Sbjct: 1 APPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMD 60 Query: 175 DGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKA 234 C GG +NA+ ++ G+++ED Y Y G +SC ++ + E+ + NE+ Sbjct: 61 KACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCQFSAEKAKVYIQDSVELSQ-NEQK 119 Query: 235 LKRAVARVGPVSVAIDASLTSFQFYSKGVYY--DESCNSDNLNHAVLAVGYGIQKGNKHW 292 L +A+ GP+SVAI+A QFY G+ C+ ++HAVL VGYG + W Sbjct: 120 LAAWLAKRGPISVAINA--FGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGQRSDVPFW 177 Query: 293 IIKNSWGENWGNKGYILMARNKNNACGIANLAS 325 IKNSWG +WG KGY + R + ACG+ +AS Sbjct: 178 AIKNSWGTDWGEKGYYYLHRG-SGACGVNTMAS 209 >3CBK-A nrPDB Length = 266 Score = 214 bits (546), Expect = 4e-56, Method: Composition-based stats. Identities = 65/262 (24%), Positives = 113/262 (43%), Gaps = 50/262 (19%) Query: 111 WEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNL--SP 164 + + P S D R++ P +++QG CGS WAF +V A+ ++ T +++ S Sbjct: 3 EDLKLPASFDAREQWPQCPTIKEIRDQGSCGSAWAFGAVEAISDRICIHTNAHVSVEVSA 62 Query: 165 QNLVDCVS--ENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQEESCMYNPT 215 ++L+ C DGC GGY A+ + + +G+ S Y PY C + Sbjct: 63 EDLLTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPY--SIPPCEAHVN 119 Query: 216 GKAAKCRGYREIPEGN---------------------------EKALKRAVARVGPVSVA 248 G C G + P+ + EK + + + GPV A Sbjct: 120 GARPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGA 179 Query: 249 IDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYI 308 + F Y GVY + HA+ +G+G++ G +W++ NSW +WG+ G+ Sbjct: 180 FSV-YSDFLLYKSGVYQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFF 237 Query: 309 LMARNKNNACGIAN--LASFPK 328 + R ++ CGI + +A P+ Sbjct: 238 KILRGQD-HCGIESEVVAGIPR 258 >4OEL-A nrPDB Length = 370 Score = 203 bits (517), Expect = 7e-53, Method: Composition-based stats. Identities = 65/248 (26%), Positives = 111/248 (44%), Gaps = 24/248 (9%) Query: 31 KTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTY-ELAMNHLGDMT--SEEVV 87 K +++Y+N++ + + +I+ ++ S TY E LGDM S Sbjct: 133 KNSQEKYSNRLYKYDHNFV-------KAINAIQKSWTATTYMEYETLTLGDMIRRSGGHS 185 Query: 88 QKMTGLK-VPLSHSRSNDTLYIP-EWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSV 145 +K+ K PL+ L++P W+ R ++ +V+PV+NQ CGSC++F+S+ Sbjct: 186 RKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGIN-----FVSPVRNQASCGSCYSFASM 240 Query: 146 GALEGQLKKKTG--KLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPY 203 G LE +++ T + LSPQ +V C GC GG+ ++ G+ E +PY Sbjct: 241 GMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPY 300 Query: 204 VGQEESCMYNPTGKAAKCRGYREI----PEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259 G + C Y + NE +K + GP++VA + F Y Sbjct: 301 TGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHY 359 Query: 260 SKGVYYDE 267 KG+Y+ Sbjct: 360 KKGIYHHT 367 >4I04-A nrPDB Length = 323 Score = 202 bits (515), Expect = 1e-52, Method: Composition-based stats. Identities = 72/319 (22%), Positives = 124/319 (38%), Gaps = 48/319 (15%) Query: 46 RRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDT 105 + + + YI+ H + N + + + L +R Sbjct: 9 FEPLSDDIISYINEHPNAGWRAEKS-----NRFHSLDDARIQMGARREEPDLRRTRRPTV 63 Query: 106 LYIPEWEGRAPDSVDYRKKGY----VTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKL-- 159 + +W P S D RKK + +++Q +CGS WAF +V A+ + ++G Sbjct: 64 DH-NDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSSWAFGAVEAMSDRSCIQSGGKQN 122 Query: 160 LNLSPQNLVDCV-SENDGCGGGYMTNAFQYVQKNR---GIDSED-----AYPYVGQEES- 209 + LS +L+ C S GC GG + A+ Y K G E+ YP+ E Sbjct: 123 VELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHT 182 Query: 210 -CMYNPTGKA--------AKCRGYREIP--------------EGNEKALKRAVARVGPVS 246 Y P G C+ + P + +EKA+++ + + GPV Sbjct: 183 KGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVE 242 Query: 247 VAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKG 306 F Y G+Y + HA+ +G+G++ +W+I NSW E+WG G Sbjct: 243 AGFTV-YEDFLNYKSGIYKHIT-GETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENG 300 Query: 307 YILMARNKNNACGIANLAS 325 Y + R ++ C I + + Sbjct: 301 YFRIVRGRD-ECSIESEVT 318 >4I05-A nrPDB Length = 285 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 67/256 (26%), Positives = 109/256 (42%), Gaps = 42/256 (16%) Query: 109 PEWEGRAPDSVDYRKKGY----VTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKL--LNL 162 +W P S D RKK + +++Q +CGSCWAF +V A+ + ++G + L Sbjct: 28 NDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVEL 87 Query: 163 SPQNLVDCV-SENDGCGGGYMTNAFQYVQKNR---GIDSED-----AYPYVGQEES--CM 211 S +L+ C S GC GG + A+ Y K G E+ YP+ E Sbjct: 88 SAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGK 147 Query: 212 YNPTGKA--------AKCRGYREIP--------------EGNEKALKRAVARVGPVSVAI 249 Y P G C+ + P + +EKA+++ + + GPV Sbjct: 148 YPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGF 207 Query: 250 DASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYIL 309 F Y G+Y + HA+ +G+G++ +W+I NSW E+WG GY Sbjct: 208 TV-YEDFLNYKSGIYKHIT-GETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFR 265 Query: 310 MARNKNNACGIANLAS 325 + R ++ C I + + Sbjct: 266 IVRGRD-ECSIESEVT 280 >4HWY-A nrPDB Length = 340 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 69/246 (28%), Positives = 96/246 (39%), Gaps = 32/246 (13%) Query: 109 PEWEGRAPDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTG-KLLNLS 163 E P S D + P + +Q CGSCWA ++ A+ + G + +++S Sbjct: 88 EEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHIS 147 Query: 164 PQNLVDCVS-ENDGCGGGYMTNAFQYVQKNRGID----------------SEDAYPYVGQ 206 +L+ C S DGC GG A+ Y + S++ YP Q Sbjct: 148 AGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQ 207 Query: 207 ----EESCMY---NPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259 C Y +PT R + E R + GP VA D F Y Sbjct: 208 FNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDV-YEDFIAY 266 Query: 260 SKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACG 319 + GVY+ S HAV VG+G G +W I NSW WG GY L+ R + CG Sbjct: 267 NSGVYHHVSGQYLG-GHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSS-ECG 324 Query: 320 IANLAS 325 I + S Sbjct: 325 IEDGGS 330 >5OGQ-A nrPDB Length = 254 Score = 194 bits (493), Expect = 5e-50, Method: Composition-based stats. Identities = 66/251 (26%), Positives = 107/251 (42%), Gaps = 42/251 (16%) Query: 114 RAPDSVDYRKKGY----VTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKL--LNLSPQNL 167 P S D RKK + +++Q +CGSCWAF +V A+ + ++G + LS +L Sbjct: 2 EIPSSFDSRKKWPRCKSIATIRDQSRCGSCWAFGAVEAMSDRSCIQSGGKQNVELSAVDL 61 Query: 168 VDCV-SENDGCGGGYMTNAFQYVQKNR---GIDSED-----AYPYVGQEES--CMYNPTG 216 + C S GC GG + A+ Y K G E+ YP+ E Y P G Sbjct: 62 LSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCG 121 Query: 217 KA--------AKCRGYREIP--------------EGNEKALKRAVARVGPVSVAIDASLT 254 C+ + P + +EKA+++ + + GPV Sbjct: 122 SKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTV-YE 180 Query: 255 SFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNK 314 F Y G+Y + HA+ +G+G++ +W+I NSW E+WG GY + R + Sbjct: 181 DFLNYKSGIYKHIT-GETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGR 239 Query: 315 NNACGIANLAS 325 + C I + + Sbjct: 240 D-ECSIESEVT 249 >2DCB-A nrPDB Length = 256 Score = 189 bits (479), Expect = 2e-48, Method: Composition-based stats. Identities = 62/251 (24%), Positives = 108/251 (43%), Gaps = 48/251 (19%) Query: 115 APDSVDYRKKGYVTP----VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNL--SPQNLV 168 P+S D R++ P +++QG CGSCWAF +V A+ ++ + +N+ S ++++ Sbjct: 1 LPESFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSNGRVNVEVSAEDML 60 Query: 169 DCVSENDGCGGG--YMTNAFQYVQKNRGIDSEDAY-------PYVGQEESCMYNPTGKAA 219 C G G + + A+ + K +G+ S Y PY C ++ G Sbjct: 61 TCCGGECGDGCNGGFPSGAWNFWTK-KGLVSGGLYNSHVGCRPY--SIPPCEHHVNGSRP 117 Query: 220 KCRGYREIPEG---------------------------NEKALKRAVARVGPVSVAIDAS 252 C G + P+ NEK + + + GPV A Sbjct: 118 PCTGEGDTPKCSKTCEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSV- 176 Query: 253 LTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMAR 312 + F Y GVY S HA+ +G+G++ G +W++ NSW +WG+ G+ + R Sbjct: 177 YSDFLLYKSGVYQHVS-GEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILR 235 Query: 313 NKNNACGIANL 323 ++ CGI + Sbjct: 236 GQD-HCGIESE 245 >4CI7-A nrPDB Length = 470 Score = 170 bits (430), Expect = 1e-42, Method: Composition-based stats. Identities = 67/284 (23%), Positives = 107/284 (37%), Gaps = 51/284 (17%) Query: 67 GVHTYELA---MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRK 123 GV T E + + +L D+ + + K G+ +P H TL +GR+ Y+ Sbjct: 11 GVETAEYSESYLQYLEDVKNGDTA-KYNGV-IPFPHEMEGTTL---RNKGRSSLPSAYKS 65 Query: 124 K--------GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN- 174 G TP KNQG + W+FS + LE LK K +LS ++L + Sbjct: 66 SVAYNPMDLGLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGK 125 Query: 175 -----DGCGGGYMTNAFQYVQKNRGIDSEDAYPY-VGQEESCMYNPTGKAAKCRGYREIP 228 D G A Y+ G E PY + E P+ + Sbjct: 126 YGWNLDDMSGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTD 185 Query: 229 ----EGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDE-----SCNSDNLNHAVL 279 +++ +K A+ + G V+ + + YS DE + LNHAV Sbjct: 186 VVRLNKDKETVKNAIMQYGSVT-------SGYAHYSTYFNKDETAYNCTNKRAPLNHAVA 238 Query: 280 AVGYGIQ------------KGNKHWIIKNSWGENWGNKGYILMA 311 VG+ + N W++K+SWGE KG+ ++ Sbjct: 239 IVGWDDNYSKDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWIS 282 >4CDF-B nrPDB Length = 166 Score = 169 bits (427), Expect = 2e-42, Method: Composition-based stats. Identities = 48/162 (29%), Positives = 75/162 (46%), Gaps = 10/162 (6%) Query: 115 APDSVDYRK---KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTG--KLLNLSPQNLVD 169 P S D+R +V+PV+NQ CGSC++F+S+G LE +++ T + LSPQ +V Sbjct: 3 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 62 Query: 170 CVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREI-- 227 C GC GG+ ++ G+ E +PY G + C Y + Sbjct: 63 CSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGG 122 Query: 228 --PEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDE 267 NE +K + GP++VA + F Y KG+Y+ Sbjct: 123 FYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHT 163 >1DEU-A nrPDB Length = 277 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 65/240 (27%), Positives = 108/240 (45%), Gaps = 28/240 (11%) Query: 90 MTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQ---GQCGSCWAFSSVG 146 + P H + W+ R D V+Y + +NQ CGSCWA +S Sbjct: 19 LGRTTYPRPHEYLSPADLPKSWDWRNVDGVNY-----ASITRNQHIPQYCGSCWAHASTS 73 Query: 147 ALEGQLKKK-TGKLLN--LSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPY 203 A+ ++ K G + LS QN++DC + C GG + + Y ++ GI E Y Sbjct: 74 AMADRINIKRKGAWPSTLLSVQNVIDCGNAGS-CEGGNDLSVWDYAHQH-GIPDETCNNY 131 Query: 204 VGQEESC-MYNPTGKAAK------CRGYREIPEGN------EKALKRAVARVGPVSVAID 250 +++ C +N G + R Y G+ + + + GP+S I Sbjct: 132 QAKDQECDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIM 191 Query: 251 ASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 A+ Y+ G+Y E ++ +NH V G+GI G ++WI++NSWGE WG +G++ + Sbjct: 192 ATER-LANYTGGIY-AEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 249 >5I4H-A nrPDB Length = 106 Score = 166 bits (421), Expect = 1e-41, Method: Composition-based stats. Identities = 70/106 (66%), Positives = 82/106 (77%), Gaps = 2/106 (1%) Query: 114 RAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV-- 171 AP SVD+R+KGYVTPVKNQGQCGS WAFS+ GALEGQ+ +KTG+L++LS QNLVDC Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 60 Query: 172 SENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGK 217 N+GC GG M AFQYVQ N G+DSE++YPY EESC YNP Sbjct: 61 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYS 106 >1EF7-A nrPDB Length = 242 Score = 164 bits (414), Expect = 7e-41, Method: Composition-based stats. Identities = 63/218 (28%), Positives = 103/218 (47%), Gaps = 26/218 (11%) Query: 115 APDSVDYRKKGYV---TPVKNQ---GQCGSCWAFSSVGALEGQLKKK-TGKLLN--LSPQ 165 P S D+R V + +NQ CGSCWA +S A+ ++ K G + LS Q Sbjct: 1 LPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQ 60 Query: 166 NLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESC-MYNPTGKAAK---- 220 N++DC + C GG + + Y ++ GI E Y +++ C +N G + Sbjct: 61 NVIDCGNAGS-CEGGNDLSVWDYAHQH-GIPDETCNNYQAKDQECDKFNQCGTCNEFKEC 118 Query: 221 --CRGYREIPEGN------EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSD 272 R Y G+ + + + GP+S I A+ Y+ G+Y E ++ Sbjct: 119 HAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATER-LANYTGGIY-AEYQDTT 176 Query: 273 NLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 +NH V G+GI G ++WI++NSWGE WG +G++ + Sbjct: 177 YINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 214 >1CSB-B nrPDB Length = 205 Score = 156 bits (394), Expect = 2e-38, Method: Composition-based stats. Identities = 49/208 (23%), Positives = 86/208 (41%), Gaps = 44/208 (21%) Query: 159 LLNLSPQNLVDCVS--ENDGCGGGYMTNAFQYVQKNRGIDSEDAY-------PYVGQEES 209 + +S ++L+ C DGC GGY A+ + + +G+ S Y PY Sbjct: 2 SVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTR-KGLVSGGLYESHVGCRPY--SIPP 58 Query: 210 CMYNPTGKAAKCRGYREIPEGN---------------------------EKALKRAVARV 242 C ++ G C G + P+ + EK + + + Sbjct: 59 CEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKN 118 Query: 243 GPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENW 302 GPV A + F Y GVY + HA+ +G+G++ G +W++ NSW +W Sbjct: 119 GPVEGAFSV-YSDFLLYKSGVYQHVT-GEMMGGHAIRILGWGVENGTPYWLVANSWNTDW 176 Query: 303 GNKGYILMARNKNNACGIAN--LASFPK 328 G+ G+ + R ++ CGI + +A P+ Sbjct: 177 GDNGFFKILRGQD-HCGIESEVVAGIPR 203 >4D59-A nrPDB Length = 406 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 52/215 (24%), Positives = 81/215 (37%), Gaps = 35/215 (16%) Query: 125 GYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEN------DGCG 178 G TP KNQG + W+FS + LE LK K +LS ++L + D Sbjct: 11 GLTTPAKNQGSLNTAWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDMS 70 Query: 179 GGYMTNAFQYVQKNRGIDSEDAYPY-VGQEESCMYNPTGKAAKCRGYREIP----EGNEK 233 G A Y+ G E PY + E P+ + +++ Sbjct: 71 GSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNKDKE 130 Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDE-----SCNSDNLNHAVLAVGYGIQ-- 286 +K A+ + G V+ + + YS DE + LNHAV VG+ Sbjct: 131 TVKNAIMQYGSVT-------SGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYS 183 Query: 287 ----------KGNKHWIIKNSWGENWGNKGYILMA 311 + N W++K+SWGE KG+ ++ Sbjct: 184 KDNFASDVKPESNGAWLVKSSWGEFNSMKGFFWIS 218 >5I4H-B nrPDB Length = 112 Score = 150 bits (380), Expect = 5e-37, Method: Composition-based stats. Identities = 57/111 (51%), Positives = 82/111 (73%), Gaps = 5/111 (4%) Query: 223 GYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVG 282 G+ +IP+ EKAL +AVA VGP+SVAIDA SF FY +G+Y++ C+S++++H VL VG Sbjct: 3 GFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVG 61 Query: 283 YGIQ----KGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM 329 YG + NK+W++KNSWGE WG GY+ MA+++ N CGIA+ AS+P + Sbjct: 62 YGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 112 >3CH2-X nrPDB Length = 265 Score = 145 bits (366), Expect = 3e-35, Method: Composition-based stats. Identities = 56/225 (24%), Positives = 88/225 (39%), Gaps = 38/225 (16%) Query: 130 VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVS--ENDGCGGGYMTNAFQ 187 V++QG C + W F+S LE K + +S + +C D C G F Sbjct: 24 VEDQGNCDTSWIFASKYHLETIRCMKGYEPTKISALYVANCYKGEHKDRCDEGSSPMEFL 83 Query: 188 YVQKNRG-IDSEDAYP--YVGQEESC----------------MYNPTGK---------AA 219 + ++ G + +E YP YV E C ++N A Sbjct: 84 QIIEDYGFLPAESNYPYNYVKVGEQCPKVEDHWMNLWDNGKILHNKNEPNSLDGKGYTAY 143 Query: 220 KCRGYREIPEGNEKALKRAVARVGPVSVAIDA-SLTSFQFYSKGVYYDESCNSDNLNHAV 278 + + + + K +K V G V I A ++ ++F K V C D +HAV Sbjct: 144 ESERFHDNMDAFVKIIKTEVMNKGSVIAYIKAENVMGYEFSGKKV--QNLCGDDTADHAV 201 Query: 279 LAVGYGIQ-----KGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318 VGYG + +WI++NSWG WG++GY + C Sbjct: 202 NIVGYGNYVNSEGEKKSYWIVRNSWGPYWGDEGYFKVDMYGPTHC 246 >5FPW-A nrPDB Length = 321 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 66/281 (23%), Positives = 104/281 (37%), Gaps = 40/281 (14%) Query: 79 GDMTSEEVVQ--KMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTP----VKN 132 G M + + ++TG + + S + P+S D +K P + + Sbjct: 37 GKMQNITFAEAKRLTGAWIQKTSSLPPVRFTEEQLRTELPESFDSAEKWPNCPTIREIAD 96 Query: 133 QGQCGSCWAFSSVGALEGQLKKKTG-KLLNLSPQNLVDCVSENDGCGGG-YMTNAFQYVQ 190 Q C + WA S+ + + G + L +S +L+ C + G G + A++Y Sbjct: 97 QSACRASWAVSTASVISDRYCTVGGVQQLRISAAHLLSCCKQCGGGCKGGFPGFAWRYYV 156 Query: 191 KNRGIDSEDAYPYVGQEESCMYN-PTGKAAKCRGYR-EIPEGN----------------- 231 + GI S PY C + G C Y + P+ Sbjct: 157 E-YGIASSYCQPYPF--PHCEHRGAQGNKTPCSKYNFDTPKCQATCTDKSIPLVKYRGSA 213 Query: 232 -------EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYG 284 E+ KR + GP VA+ T Y GVY AV VG+G Sbjct: 214 TYLLLHGEEDYKRELYFNGPF-VAVFYVYTDLFAYKSGVYRHVD-GDFLGGTAVKVVGWG 271 Query: 285 IQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLAS 325 G +W + N+W +WG GY+L+ R NN C I +L Sbjct: 272 KLNGTPYWKVANTWDTDWGMDGYLLILRG-NNECNIEHLGF 311 >1SP4-B nrPDB Length = 205 Score = 128 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 41/177 (23%), Positives = 70/177 (39%), Gaps = 40/177 (22%) Query: 181 YMTNAFQYVQKNRGIDSEDAY-------PYVGQEESCMYNPTGKAAKCRGYREIPEGN-- 231 + + A+ + K +G+ S Y PY C ++ G C G + P+ N Sbjct: 27 FPSGAWNFWTK-KGLVSGGLYNSHVGCRPY--SIPPCEHHVNGSRPPCTGEGDTPKCNKT 83 Query: 232 -------------------------EKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYD 266 EK + + + GPV A + F Y GVY Sbjct: 84 CEPGYSPSYKEDKHFGCSSYSVANNEKEIMAEIYKNGPVEGAFSV-YSDFLLYKSGVYQH 142 Query: 267 ESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANL 323 S HA+ +G+G++ G +W++ NSW +WG+ G+ + R ++ CGI + Sbjct: 143 VS-GEIMGGHAIRILGWGVENGTPYWLVGNSWNTDWGDNGFFKILRGQD-HCGIESE 197 >4OEM-B nrPDB Length = 70 Score = 84.7 bits (208), Expect = 5e-17, Method: Composition-based stats. Identities = 26/61 (42%), Positives = 33/61 (54%), Gaps = 3/61 (4%) Query: 266 DESCNSDNLNHAVLAVGYGIQK--GNKHWIIKNSWGENWGNKGYILMARNKNNACGIANL 323 D + NHAVL VGYG G +WI+KNSWG WG GY + R + C I ++ Sbjct: 1 DPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTD-ECAIESI 59 Query: 324 A 324 A Sbjct: 60 A 60 >2L95-A nrPDB Length = 80 Score = 77.7 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 2/76 (2%) Query: 21 ILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGD 80 + D W +K K Y +++ RR I+ ++ I HN + G T+++ +NHL D Sbjct: 5 VSDEEWVEYKSKFDKNYE-AEEDLMRRRIYAESKARIEEHNRKFEKGEVTWKMGINHLAD 63 Query: 81 MTSEEVVQKMTGLKVP 96 +T EE Q+ +G KVP Sbjct: 64 LTPEEFAQR-SGKKVP 78 >3OIS-A nrPDB Length = 291 Score = 56.9 bits (136), Expect = 1e-08, Method: Composition-based stats. Identities = 47/227 (20%), Positives = 78/227 (34%), Gaps = 45/227 (19%) Query: 115 APDSVDYRKKGYVTP---VKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCV 171 P VD +TP V +QG+ GSC A + A++ + + P L + Sbjct: 57 LPPKVD------LTPPFQVYDQGRIGSCTANALAAAIQ-FERIHDKQSPEFIPSRLF--I 107 Query: 172 SENDGCGGGYMTNAFQYVQKNR-------GIDSEDAYPY-------------------VG 205 N+ G++ + ++ G+ E +PY Sbjct: 108 YYNERKIEGHVNYDSGAMIRDGIKVLHKLGVCPEKEWPYGDTPADPRTEEFPPGAPASKK 167 Query: 206 QEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYS--KGV 263 + C + K Y + + + LK +A P + S + Sbjct: 168 PSDQCYKDAQN--YKITEYSRVAQ-DIDHLKACLAVGSPFVFGFSVYNSWVGNNSLPVRI 224 Query: 264 YYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILM 310 ++ HAVL VGY + +H+ I+NSWG N G GY M Sbjct: 225 PLPTKNDTLEGGHAVLCVGYDDE--IRHFRIRNSWGNNVGEDGYFWM 269 >5WDK-A nrPDB Length = 401 Score = 44.2 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 13/89 (14%) Query: 123 KKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSP--------QNLVDCVSEN 174 K+ +T VKNQ + G+CW +SS LE +L + +LS + D Sbjct: 36 KENPITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEMFTVYNTYLDRADAAVRT 95 Query: 175 DGC----GGGYMTNAFQYVQKNRGIDSED 199 G GG +A Y + G+ E+ Sbjct: 96 HGDVSFSQGGSFYDAL-YGMETFGLVPEE 123 Score = 35.7 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 275 NHAVLAVGYGI-QKGNKHWIIKNSWGENWGNKGYILMAR 312 +H + G Q+GN+++++KNSWG N G ++ Sbjct: 335 DHGMQIYGIAKDQEGNEYYMVKNSWGTNSKYNGIWYASK 373 >4K7C-A nrPDB Length = 446 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 268 SCNSDNLNHAVLAVGYGIQKGNKH-WIIKNSWGENWGNKGYI 308 + HA++ G + G W ++NSWGE G KGY Sbjct: 356 DYGESLMTHAMVLTGVDLVDGKPTKWKVENSWGEKVGEKGYF 397 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 16/30 (53%), Gaps = 4/30 (13%) Query: 130 VKNQGQCGSCWAFSSVGAL----EGQLKKK 155 V NQ Q G CW F+++ + + Q K K Sbjct: 61 VSNQKQSGRCWMFAALNTMRHGIQAQFKIK 90 >2CB5-A nrPDB Length = 453 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 4/45 (8%) Query: 270 NSDNLNHAVLAVGYGIQKGNK----HWIIKNSWGENWGNKGYILM 310 + HA+ + W ++NSWGE+ G+KGY+ M Sbjct: 365 GESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCM 409 >2QGM-A nrPDB Length = 445 Score = 33.4 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 27/75 (36%), Gaps = 10/75 (13%) Query: 140 WAFSSVGALEGQLKKKTGKL----LNLSPQNLVD---CVSENDGCGGGYMTNAFQYVQKN 192 WA ++ A+E + L Q L D E G G M A + Sbjct: 255 WAKATASAIEKFTTMLLPNDYPSIIKLHEQYLADHAMWAQETFG--GKTMVWAHN-IHIA 311 Query: 193 RGIDSEDAYPYVGQE 207 +GI E YPYV + Sbjct: 312 KGIIDEKLYPYVAGQ 326 >1A6R-A nrPDB Length = 471 Score = 31.5 bits (70), Expect = 0.49, Method: Composition-based stats. Identities = 33/179 (18%), Positives = 61/179 (34%), Gaps = 46/179 (25%) Query: 186 FQYVQKNRGIDSEDAYP------YVGQEESCMY-------NPTGKAAKCRGYREIPEGNE 232 ++YV K++ I + + P Y + S +P GK K + G+ Sbjct: 254 WEYVDKDKKIHTIKSTPLEFASKYAKLDPSTPVSLINDPRHPYGKLIKIDRLGNVLGGDA 313 Query: 233 --------KALKRAVAR--VGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLN------- 275 + L + V + +V + F GV E N + Sbjct: 314 VIYLNVDNETLSKLVVKRLQNNKAVFFGSHTPKFMDKKTGVMDIELWNYPAIGYNLPQQK 373 Query: 276 ------------HAVLAVGYGIQKGNKH---WIIKNSWGENWGNKG-YILMARNKNNAC 318 HA+L G + + +K + ++NSWG++ G G Y++ + C Sbjct: 374 ASRIRYHESLMTHAMLITGCHVDETSKLPLRYRVENSWGKDSGKDGLYVMTQKYFEEYC 432 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 17/40 (42%), Gaps = 9/40 (22%) Query: 128 TPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNL 167 TPV NQ G W F++ L +L LS NL Sbjct: 79 TPVTNQKSSGRAWLFAATNQL---------RLNVLSELNL 109 >1X9Y-A nrPDB Length = 367 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 35/233 (15%), Positives = 58/233 (24%), Gaps = 57/233 (24%) Query: 78 LGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCG 137 L + E+ K ++ + + E E D V Y ++ Q Sbjct: 147 LANNIKEKESAKTVSPQLKQELKTTVTPTKVEENEAIQEDQVQYENTLKNFKIREQQFDN 206 Query: 138 S-CWAFSSVGALEGQLKKKTGKL--------LNLSPQNLVDCVSENDGCGGGYMTNAFQY 188 S C FS L T +S Q+L +C + + +Y Sbjct: 207 SWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSEQDLPNCAT--------FPNQMIEY 258 Query: 189 VQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVA 248 G Y ++ + N + A VS Sbjct: 259 -----GKSQGRDIHYQ-----------EGVPSYNQVDQLTKDNVGIMILA----QSVS-- 296 Query: 249 IDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGEN 301 ++ N +L HA+ VG + I N W Sbjct: 297 ------------------QNPNDPHLGHALAVVGNAKINDQEKLIYWNPWDTE 331 >1G0D-A nrPDB Length = 695 Score = 31.5 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 14/38 (36%), Positives = 17/38 (44%), Gaps = 5/38 (13%) Query: 109 PEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVG 146 W G P + K G V PVK G CW F++V Sbjct: 247 YRWTGSVPILQQWSKAG-VRPVKY----GQCWVFAAVA 279 >2V0O-A nrPDB Length = 276 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 31/88 (35%), Gaps = 1/88 (1%) Query: 32 THRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMT 91 ++ YN K E R + I +++ TY+L + + + QKMT Sbjct: 140 KSKENYNAKCVEQERLKKEGATQREIEKAAVKSKKATDTYKLYVEKYA-LAKADFEQKMT 198 Query: 92 GLKVPLSHSRSNDTLYIPEWEGRAPDSV 119 ++I E G +++ Sbjct: 199 ETAQKFQDIEETHLIHIKEIIGSLSNAI 226 >1L9N-A nrPDB Length = 692 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 18/41 (43%), Gaps = 13/41 (31%) Query: 113 GRAPDSVD--------YRKKGYVTPVKNQGQCGSCWAFSSV 145 GR P S D ++K G +PV+ G CW F+ Sbjct: 243 GRDPRSWDGSVEILKNWKKSGL-SPVRY----GQCWVFAGT 278 >2Z51-A nrPDB Length = 154 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 10/15 (66%), Positives = 10/15 (66%) Query: 125 GYVTPVKNQGQCGSC 139 G V VK QG CGSC Sbjct: 34 GNVVRVKLQGACGSC 48 >3EUP-A nrPDB Length = 204 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 26/160 (16%), Positives = 48/160 (30%), Gaps = 17/160 (10%) Query: 10 PVVSFALYPEEILDTHWELWKKTHRKQYNNKVD-EISRRLIWEKNLKYISIHNLEASLGV 68 PV + L E T Y N + E ++ N ++ Sbjct: 22 PVFNVKGLAGTSLTDLTEATNLTKGSIYGNFENKEAVAIAAFDYNWGHVKSVLTAKVQAC 81 Query: 69 HTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVT 128 +TY+ + M ++ PL ++ +A +++ KK VT Sbjct: 82 NTYKEMLLVYSSMYNDADGSLFPVGGCPLLNTTIEADDTHDALRKKAGEAILSWKKNLVT 141 Query: 129 PVKNQGQCG------------SCWAFSSVGALEGQLKKKT 156 +K G + AFS + +EG + Sbjct: 142 IIKK----GIQAKEFRPDTDVTKIAFSMIALVEGAILIHR 177 >5ZRD-A nrPDB Length = 549 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 5/61 (8%) Query: 179 GGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRA 238 GGY FQY + + +D YPY G C + G +R E+AL+ Sbjct: 54 GGYHGEPFQYRKPVDALPQDDIYPYWG--GYCNH---GNVLFPTWHRMYVYKLEEALQSI 108 Query: 239 V 239 V Sbjct: 109 V 109 >2WQK-A nrPDB Length = 251 Score = 28.4 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 8/50 (16%), Positives = 17/50 (34%), Gaps = 1/50 (2%) Query: 248 AIDASLTSFQFYSKGVYYDESCNSDNLNH-AVLAVGYGIQKGNKHWIIKN 296 I + + Y + V+ A G+ ++G +W + N Sbjct: 174 GIKVTRQGKRAYKERVFKYIDPYGKPFYWIAAEEFGWHAEEGTDYWAVLN 223 >4WFK-A nrPDB Length = 273 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 11/94 (11%) Query: 224 YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF-YSKGVYYDESCNSDNLNHAVLAV- 281 Y P+ E +++ A GP SVA + ++SF + G Y + AV Sbjct: 15 YERGPDPTEDSIE---AIRGPFSVATE-RVSSFASGFGGGTIYYPRETDEGTFGAVAVAP 70 Query: 282 GYGIQKGNKHWIIKNSWGENWGNKGYILMARNKN 315 G+ +G+ W +GE ++G+I+ + N Sbjct: 71 GFTASQGSMSW-----YGERVASQGFIVFTIDTN 99 >5DMY-A nrPDB Length = 904 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 36/145 (24%), Gaps = 19/145 (13%) Query: 170 CVSENDGCGGGYMTNAFQY--VQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREI 227 G G + + Y + G + Y Y Q + Sbjct: 609 WNGTGSGAVGSWPSPKNSYFGIVDTAGFPKDTYYFYQSQ----------WNDDVHTLHIL 658 Query: 228 PEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQ- 286 P NE + + PV V DA+ F KG + A GY Q Sbjct: 659 PAWNENVVAKGSGNKVPVVVYTDAAKVKLYFTPKGSTEKRLIGEKSFTKKTTAAGYTYQV 718 Query: 287 ---KGNKHWIIKN---SWGENWGNK 305 KN +W W Sbjct: 719 YEGTDKDSTAHKNMYLTWNVPWAEG 743 >4Z04-A nrPDB Length = 131 Score = 27.7 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 16/37 (43%), Gaps = 3/37 (8%) Query: 260 SKGVYYDESCNSDNLNHAVLA---VGYGIQKGNKHWI 293 +YD + + + HA+ VGYG + WI Sbjct: 22 KSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWI 58 >1H33-A nrPDB Length = 261 Score = 27.7 bits (60), Expect = 8.0, Method: Composition-based stats. Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 11/74 (14%) Query: 234 ALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDE---------SCNSDNLNHAVLA--VG 282 AL +V+R PVSVAID S + +YY SC+ +H + A + Sbjct: 136 ALIASVSRGMPVSVAIDGPAQSTWEKGREIYYTRYGQLDLSCASCHEQYFDHYIRADHLS 195 Query: 283 YGIQKGNKHWIIKN 296 G G + +KN Sbjct: 196 QGQINGFPSYRLKN 209 >2JNV-A nrPDB Length = 91 Score = 27.3 bits (59), Expect = 9.4, Method: Composition-based stats. Identities = 9/15 (60%), Positives = 10/15 (66%) Query: 125 GYVTPVKNQGQCGSC 139 G V +K QG CGSC Sbjct: 35 GNVVRLKLQGACGSC 49 >4CTH-A nrPDB Length = 709 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 34/113 (30%), Gaps = 26/113 (23%) Query: 90 MTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQC------GSCWAFS 143 G+ + + H ++ + D VD+ + + K Q QC W + Sbjct: 534 YGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLA 593 Query: 144 SVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGY--MTNAFQ-YVQKNR 193 L G EN GG A+Q Y++KN Sbjct: 594 GGQHLNGINTL-----------------GENIADNGGLGQAYRAYQNYIKKNG 629 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.140 0.447 Lambda K H 0.267 0.0426 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,156,116 Number of Sequences: 36641 Number of extensions: 600628 Number of successful extensions: 2181 Number of sequences better than 10.0: 103 Number of HSP's better than 10.0 without gapping: 170 Number of HSP's successfully gapped in prelim test: 20 Number of HSP's that attempted gapping in prelim test: 1446 Number of HSP's gapped (non-prelim): 217 length of query: 329 length of database: 10,336,785 effective HSP length: 97 effective length of query: 232 effective length of database: 6,782,608 effective search space: 1573565056 effective search space used: 1573565056 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)