BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P43166 (264 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6G4T-A nrPDB 548 e-156 4QK3-A nrPDB 304 2e-83 1FLJ-A nrPDB 300 6e-82 3D0N-A nrPDB 298 1e-81 4CNR-A nrPDB 298 2e-81 6FAF-A nrPDB 293 7e-80 1Z93-A nrPDB 283 4e-77 1URT-A nrPDB 271 3e-73 2W2J-A nrPDB 213 6e-56 1RJ5-A nrPDB 171 4e-43 5LL9-A nrPDB 167 4e-42 5DVX-A nrPDB 161 2e-40 3FE4-A nrPDB 157 6e-39 4LU3-A nrPDB 155 1e-38 4X5S-A nrPDB 147 4e-36 4ETQ-X nrPDB 141 4e-34 6B9J-X nrPDB 140 5e-34 5JN8-A nrPDB 136 1e-32 4COQ-A nrPDB 133 7e-32 4G7A-A nrPDB 130 9e-31 6EKI-A nrPDB 127 7e-30 3ZNC-A nrPDB 125 1e-29 5HPJ-A nrPDB 123 6e-29 1KOQ-A nrPDB 113 6e-26 4XZ5-A nrPDB 113 8e-26 4XIW-A nrPDB 102 1e-22 4TWL-A nrPDB 93 1e-19 5TT3-A nrPDB 79 1e-15 3B1B-A nrPDB 74 4e-14 3Q31-A nrPDB 74 8e-14 1Y7W-A nrPDB 69 2e-12 6HIV-DP nrPDB 28 4.8 4POR-A nrPDB 28 5.3 4MBZ-A nrPDB 28 5.9 >6G4T-A nrPDB Length = 274 Score = 548 bits (1411), Expect = e-156, Method: Compositional matrix adjust. Identities = 262/264 (99%), Positives = 262/264 (99%) Query: 1 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS 60 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS Sbjct: 3 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS 62 Query: 61 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 120 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL Sbjct: 63 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 122 Query: 121 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC Sbjct: 123 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 182 Query: 181 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 FNPK LLPASRHYWTYPGSLTTPPLSESVTWIVLREPI ISERQMGKFRSLLFTSEDDER Sbjct: 183 FNPKSLLPASRHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDER 242 Query: 241 IHMVNNFRPPQPLKGRVVKASFRA 264 IHMVNNFRPPQPLKGRVVKASFRA Sbjct: 243 IHMVNNFRPPQPLKGRVVKASFRA 266 >4QK3-A nrPDB Length = 249 Score = 304 bits (779), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 144/259 (55%), Positives = 182/259 (70%), Gaps = 12/259 (4%) Query: 5 HGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNN 64 H WGYG+ +GP HWHK +PIA+G+RQSP++I + A Y PSL+PL +SY+ SL I NN Sbjct: 3 HHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNN 62 Query: 65 GHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 124 GH+ V+F+DS D+ V+ GGPL+G YRL QFHFHWG GSEHTVD K + +ELHLVH Sbjct: 63 GHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVH 122 Query: 125 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPK 184 WN KY FG+A PDGLAV+G+FL+ G P + ++ D L ++ KG A F+ F+P+ Sbjct: 123 WNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPR 181 Query: 185 CLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMV 244 LLP S YWTYPGSLTTPPL E VTWIVL+EPI +S Q+ KFR L MV Sbjct: 182 GLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL-----------MV 230 Query: 245 NNFRPPQPLKGRVVKASFR 263 +N+RP QPLK R +KASF+ Sbjct: 231 DNWRPAQPLKNRQIKASFK 249 >1FLJ-A nrPDB Length = 260 Score = 300 bits (767), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 138/257 (53%), Positives = 183/257 (71%), Gaps = 1/257 (0%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66 WGY +GP HWH+LYPIA+GD QSPI + + + PSLQP +SY+ + +I NNG Sbjct: 5 WGYASHNGPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKTILNNGK 64 Query: 67 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 + +V F+D+ DR+++ GGPL GPYRL+QFH HWG D GSEHTVDG + +ELHLVHWN Sbjct: 65 TCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN 124 Query: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186 KY+TFGEA PDG+AVVG+FL+ G E L DAL ++ KG +A F+ F+P CL Sbjct: 125 P-KYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPSCL 183 Query: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246 PA R YWTY GS TTPP E + W++L+EP+ +S QM K RSL ++E++ + +V N Sbjct: 184 FPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLVGN 243 Query: 247 FRPPQPLKGRVVKASFR 263 +RPPQP+KGRVV+ASF+ Sbjct: 244 WRPPQPIKGRVVRASFK 260 >3D0N-A nrPDB Length = 264 Score = 298 bits (763), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 138/256 (53%), Positives = 186/256 (72%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66 WGY + +GP HW + +PIA GD+QSPI I + + Y SL+PL + Y+ + I+N+GH Sbjct: 8 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 67 Query: 67 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 S VDF+D+++++V+ GGPL G YRL+Q H HWG D GSEH VDG S+ +ELH+VHWN Sbjct: 68 SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 127 Query: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186 + KY +F EAA PDGLAV+GVFL+ G+ + + ++TD L ++ KG + +F+ F+ L Sbjct: 128 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 187 Query: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246 LP S YWTYPGSLT PPL ESVTWIVL++PI IS +Q+ KFRSLL T+E + +V+N Sbjct: 188 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 247 Query: 247 FRPPQPLKGRVVKASF 262 RPPQPLKGR V+ASF Sbjct: 248 HRPPQPLKGRKVRASF 263 >4CNR-A nrPDB Length = 262 Score = 298 bits (763), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 142/260 (54%), Positives = 178/260 (68%), Gaps = 1/260 (0%) Query: 1 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS 60 M H WGY + +GP HWHK +PIA G+RQSP++I + V P+L+PL L Y S Sbjct: 1 MGMSHHWGYDKHNGPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRR 60 Query: 61 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 120 + N+GHS V+++DS D+ V+ GPL G YRL QFHFHWG D GSEHTVD K + +EL Sbjct: 61 MVNDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAEL 120 Query: 121 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180 HLVHWN KY FG AA PDGLAVVGVFL+ GD +P++ ++ DAL ++ KG F Sbjct: 121 HLVHWNT-KYGDFGTAAQEPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPN 179 Query: 181 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 F+P LLP YWTYPGSLTTPPL ESVTWIVL+EPI +S +QM KFR+L F +E + Sbjct: 180 FDPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPE 239 Query: 241 IHMVNNFRPPQPLKGRVVKA 260 M+ N+RP QPLK R V+ Sbjct: 240 ELMLANWRPAQPLKNRQVRG 259 >6FAF-A nrPDB Length = 261 Score = 293 bits (749), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 132/256 (51%), Positives = 178/256 (69%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66 WGY +GP W KLYPIA G+ QSP++I +S+ + SL+P+ +SY + I N GH Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH 65 Query: 67 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 S V+F D+D+R+V+ GGP YRL QFHFHWG ++ GSEHTVDG + +ELH+ HWN Sbjct: 66 SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWN 125 Query: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186 + KYS+ EAAS DGLAV+GV ++ G+ +P + ++ DAL ++ KG +A F+ F+P L Sbjct: 126 SAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTL 185 Query: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246 LP+S +WTYPGSLT PPL ESVTWI+ +E I +S Q+ +FRSLL E D + M +N Sbjct: 186 LPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHN 245 Query: 247 FRPPQPLKGRVVKASF 262 RP QPLKGR V+ASF Sbjct: 246 NRPTQPLKGRTVRASF 261 >1Z93-A nrPDB Length = 266 Score = 283 bits (725), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 130/257 (50%), Positives = 180/257 (70%), Gaps = 1/257 (0%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66 WGY +GP HWH+L+P A+G+ QSPI + + + PSLQP +SY+ + +I NNG Sbjct: 5 WGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGK 64 Query: 67 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 + +V F+D+ DR+++ GGPL GPYRL+QFH HWG D GSEHTVDG + +ELHLVHWN Sbjct: 65 TCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWN 124 Query: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186 KY+TF EA DG+AV+G+FL+ G E+ DAL ++ KG +A F+ F+P L Sbjct: 125 P-KYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSSL 183 Query: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246 PASR YWTY GS TTPP E + W++L+EP+ +S QM K RSLL ++E++ + +V+N Sbjct: 184 FPASRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSN 243 Query: 247 FRPPQPLKGRVVKASFR 263 +RPPQP+ RVV+ASF+ Sbjct: 244 WRPPQPINNRVVRASFK 260 >1URT-A nrPDB Length = 248 Score = 271 bits (692), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 126/239 (52%), Positives = 168/239 (70%) Query: 25 AQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGG 84 A+G RQSPINI +VY P L PL +SY+A + N GH+ QV+F+DS + + ++GG Sbjct: 2 AEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISGG 61 Query: 85 PLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLA 144 PL YRLKQFHFHWG + GSEH VDG ++P+ELHLVHWN+ KY + +A+ +GLA Sbjct: 62 PLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLA 121 Query: 145 VVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPP 204 V+GVFL+ G H ++ +L D L VR K T+ F+P CL+PA R YWTYPGSLTTPP Sbjct: 122 VIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRDYWTYPGSLTTPP 181 Query: 205 LSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFR 263 L+ESVTWIV + P+ +S Q+ FR+LLF+ +E MVNN+RP QPL+ R +++SFR Sbjct: 182 LAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR 240 >2W2J-A nrPDB Length = 291 Score = 213 bits (542), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 108/258 (41%), Positives = 159/258 (61%), Gaps = 14/258 (5%) Query: 17 HWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS--YEACMSLSITNNGHSVQVDFND 74 W ++P A G+ QSPIN+ S +A Y PSL + LS Y C +TN+GH++QV Sbjct: 37 EWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS 96 Query: 75 SDDRTVVTGGPL-EG-PYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYST 132 ++V++GGPL +G + L + FHWG+++ GSEHTV+ K+FP ELHL+HWN+ + + Sbjct: 97 ---KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGS 153 Query: 133 FGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLL--PAS 190 EA P G+A++ +F++ G EH + +T+ L +++KG CFNP LL P Sbjct: 154 IDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLL 213 Query: 191 RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIH-----MVN 245 R YW Y GSLT PP SE VTWI+ R P+ IS+ Q+ +FR L + E + + + Sbjct: 214 RDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGD 273 Query: 246 NFRPPQPLKGRVVKASFR 263 NFRP QPL RV++A+F+ Sbjct: 274 NFRPTQPLSDRVIRAAFQ 291 >1RJ5-A nrPDB Length = 261 Score = 171 bits (432), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 99/266 (37%), Positives = 144/266 (54%), Gaps = 11/266 (4%) Query: 3 GHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSL---QPLELSYEACMSL 59 G H W Y G HW YP GD QSPINI + ++ P L QP L Sbjct: 1 GGHHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPL 60 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV-GSEHTVDGKSFPS 118 + NNGH+VQ+ T+ GG L Y Q H HWG++ + GSEH ++ ++ + Sbjct: 61 DLHNNGHTVQLSL----PPTLHLGG-LPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAA 115 Query: 119 ELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD-EHPSMNRLTDALYMVRFKGTKAQ 177 ELH+VH++++ YS+ EAA P GLAV+G+ +E G+ E+P+ + + L+ +R+K K Sbjct: 116 ELHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTS 175 Query: 178 FSCFNPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSE 236 F+ + L P ++ Y GSLTTPP +SV W V IS Q+ K + L ++E Sbjct: 176 VPPFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTE 235 Query: 237 DDERIHMVNNFRPPQPLKGRVVKASF 262 +D +V N+R PQPL R + ASF Sbjct: 236 EDPSEPLVQNYRVPQPLNQRTIFASF 261 >5LL9-A nrPDB Length = 263 Score = 167 bits (424), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 103/263 (39%), Positives = 145/263 (55%), Gaps = 12/263 (4%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLEL---SYEACMSLSITN 63 W Y DG + W K YP G QSPI++ S Y SL PLE + A +TN Sbjct: 4 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 63 Query: 64 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV-GSEHTVDGKSFPSELHL 122 NGHSV+++ SD + G L+ Y Q H HWG +D GSEHTV G+ F +ELH+ Sbjct: 64 NGHSVKLNL-PSDMH--IQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 118 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFN 182 VH+N+ Y A++ +GLAV+ V +E G +PS +++ L V++KG +A FN Sbjct: 119 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 178 Query: 183 PKCLLPA-SRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS--EDDE 239 + LLP + Y+ Y GSLTTPP + +V W V R P+ IS+ Q+ + L+ + +D Sbjct: 179 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 238 Query: 240 RIHMVNNFRPPQPLKGRVVKASF 262 M+NNFR Q R+V SF Sbjct: 239 PREMINNFRQVQKFDERLVYTSF 261 >5DVX-A nrPDB Length = 260 Score = 161 bits (408), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 100/263 (38%), Positives = 141/263 (53%), Gaps = 16/263 (6%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS---YEACMSLSITN 63 W YG D W ++ P G QSP++I A +SP+L+PLELS L + N Sbjct: 2 WRYGGD---PPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLRN 58 Query: 64 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLV 123 NGHSVQ+ + + G YR Q H HWG GSEHTV+G FP+E+H+V Sbjct: 59 NGHSVQLTLPPGLEMKLGPGRE----YRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVV 114 Query: 124 HWNAKKYSTFGEAASAPDGLAVVGVFLETG-DEHPSMNRLTDALYMVRFKGTKAQFSCFN 182 H + KY+ EA P GLAV+ FLE G +E+ + +L L + +G++ Q + Sbjct: 115 HLST-KYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLD 173 Query: 183 PKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 LLP+ Y+ Y GSLTTPP ++ V W V + + +S +Q+ L+ D R+ Sbjct: 174 ISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLW-GPGDSRL 232 Query: 242 HMVNNFRPPQPLKGRVVKASFRA 264 + NFR QPL GRV++ASF A Sbjct: 233 QL--NFRATQPLNGRVIEASFPA 253 >3FE4-A nrPDB Length = 278 Score = 157 bits (396), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 95/254 (37%), Positives = 145/254 (57%), Gaps = 15/254 (5%) Query: 16 SHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS-YEA-CMSLSITNNGHSVQVDFN 73 +HW + YP G RQSPIN+ ++ Y+PSL+ L ++ YE + NNGH+VQ+ Sbjct: 14 AHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLP 73 Query: 74 DSDDRTVVTGGPLEGPYRLKQFHFHWG--KKHDVGSEHTVDGKSFPSELHLVHWNAKKYS 131 + TV G Y +Q HFHWG GSEHTVDG E+H+VH+N+K Y Sbjct: 74 STMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSK-YK 128 Query: 132 TFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPA 189 ++ A APDGLAV+ F+E + E+ + L +++ G + + + + +LP Sbjct: 129 SYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPR 188 Query: 190 S-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFR 248 + +HY+TY GSLTTPP +E+V W VL + + +S Q+ K + L ++ IH N++R Sbjct: 189 NLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-DHRNKTIH--NDYR 245 Query: 249 PPQPLKGRVVKASF 262 QPL RVV+++F Sbjct: 246 RTQPLNHRVVESNF 259 >4LU3-A nrPDB Length = 279 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 97/266 (36%), Positives = 138/266 (51%), Gaps = 11/266 (4%) Query: 3 GHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYS---PSLQPLELSYEACMSL 59 G W Y G HW YP + QSPI+I + + P+LQP L Sbjct: 3 GGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPL 62 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV-GSEHTVDGKSFPS 118 + NNGH+VQ+ T+ GG L Y Q H HWG+K GSEH ++ ++ + Sbjct: 63 DLHNNGHTVQLSL----PSTLYLGG-LPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFA 117 Query: 119 ELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD-EHPSMNRLTDALYMVRFKGTKAQ 177 ELH+VH+++ Y + EAA P GLAV+G+ +E G+ ++ + + L+ VR K K Sbjct: 118 ELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTS 177 Query: 178 FSCFNPKCLLPASR-HYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSE 236 FN + LLP Y+ Y GSLTTPP +SV W V IS Q+ K + LF++E Sbjct: 178 VPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTE 237 Query: 237 DDERIHMVNNFRPPQPLKGRVVKASF 262 ++ +V N+R QPL R+V ASF Sbjct: 238 EEPSKLLVQNYRALQPLNQRMVFASF 263 >4X5S-A nrPDB Length = 232 Score = 147 bits (372), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 95/266 (35%), Positives = 143/266 (53%), Gaps = 43/266 (16%) Query: 1 MTGHHGWGYGQDDGPSHWHKLYPI---AQGDRQSPINIISSQAVYSPSLQPLELSYEACM 57 M H W Y ++GP +W KL P QSP++I + V++ L+ L ++Y + Sbjct: 4 MAEVHHWSYEGENGPENWAKLNPEYFWCNLKNQSPVDISDNYKVHA-KLEKLHINYNKAV 62 Query: 58 SLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFP 117 + I NNGH++QV+ + D + + G Y LKQFHFH SEHTV+GK +P Sbjct: 63 NPEIVNNGHTIQVNVLE-DFKLNIKGKE----YHLKQFHFH------APSEHTVNGKYYP 111 Query: 118 SELHLVHWNAKKYSTFGEAASAPDG-LAVVGVFLETGDEHPSMNRL-TDALYMVRFKGTK 175 E+HLVH DG +AV+GVF + G +P ++++ +AL + +G+K Sbjct: 112 LEMHLVH-------------KDKDGNIAVIGVFFKEGKANPELDKVFKNAL---KEEGSK 155 Query: 176 AQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS 235 N LLP ++Y+TY GSLTTPP +E V WIVL++PI S++Q+ F+S++ Sbjct: 156 VFDGSININALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIM--- 212 Query: 236 EDDERIHMVNNFRPPQPLKGRVVKAS 261 NN RP QP+ R + S Sbjct: 213 -------KHNNNRPTQPINSRYILES 231 >4ETQ-X nrPDB Length = 269 Score = 141 bits (355), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 83/242 (34%), Positives = 127/242 (52%), Gaps = 17/242 (7%) Query: 31 SPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPY 90 SPINI + +A+ + L+PL++ Y +I N G V+++F ++GG L Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLPNEY 61 Query: 91 RLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFL 150 L H +WGK+ D GS H +D + E++LVHWN KKYS++ EA DGL ++ +FL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 151 ETGD-EHPSMNRLTDALYMVRFKGTKAQF-SCFNPKCLLPASRHYWTYPGSLTTPPLSES 208 + D ++ ++ + L +R T A F S F LLP+ Y+TY G TT S Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 209 VTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVN-NFRPPQPLK--------GRVVK 259 WI+ PI I Q+ KFR+LL S + + H + N+R P L G +++ Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLNDDTEVYYSGEIIR 239 Query: 260 AS 261 A+ Sbjct: 240 AA 241 >6B9J-X nrPDB Length = 241 Score = 140 bits (353), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 81/226 (35%), Positives = 121/226 (53%), Gaps = 9/226 (3%) Query: 31 SPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPY 90 SPINI + +A+ + L+PL++ Y +I N G V+++F ++GG L Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLPNEY 61 Query: 91 RLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFL 150 L H +WGK+ D GS H +D + E++LVHWN KKYS++ EA DGL ++ +FL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 151 ETGD-EHPSMNRLTDALYMVRFKGTKAQF-SCFNPKCLLPASRHYWTYPGSLTTPPLSES 208 + D ++ ++ + L +R T A F S F LLP+ Y+TY G TT S Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 209 VTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVN-NFRPPQPL 253 WI+ PI I Q+ KFR+LL S + + H + N+R P L Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKL 225 >5JN8-A nrPDB Length = 266 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 93/269 (34%), Positives = 134/269 (49%), Gaps = 21/269 (7%) Query: 7 WGYGQDDGPSHWHKLYPI-----AQGDRQSPINIISSQAVYSPSLQPLELS-YEACMSLS 60 W Y S++ L P+ Q DRQSPINI++++A L S Y+ + + Sbjct: 5 WCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWT 64 Query: 61 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 120 + NNGHSV + +++ ++GG L PY+ KQ H HW GSEH++DG+ F E+ Sbjct: 65 VQNNGHSVMMLL---ENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 121 Query: 121 HLVHWNAKKYS-TFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMV---RFKGTK 175 H+VH K S EA D +AV+ +E G + + L +AL + T Sbjct: 122 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTM 181 Query: 176 AQFSCFNPKCLLPAS---RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLL 232 A+ S + LLP RHY+ Y GSLTTP E V W V REPI + Q+ F L Sbjct: 182 AESSLLD---LLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKL 238 Query: 233 FTSEDDERIHMVNNFRPPQPLKGRVVKAS 261 + + ++ + M +N RP Q L R V S Sbjct: 239 YY-DKEQTVSMKDNVRPLQQLGQRTVIKS 266 >4COQ-A nrPDB Length = 247 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 93/257 (36%), Positives = 126/257 (49%), Gaps = 42/257 (16%) Query: 7 WGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSIT 62 WGY GP HW L P G QSPI+I S+ AV + L P+ + Y + + Sbjct: 26 WGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVKA-CLAPVSVYY-VSDAKYVV 83 Query: 63 NNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 NNGH+++V VV G + LKQFHFH SEHTV+GK +P E H Sbjct: 84 NNGHTIKVVMGGRG--YVVVDGKR---FYLKQFHFH------APSEHTVNGKHYPFEAHF 132 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC-F 181 VH + + V+GVF + G E+P + ++ M G K + Sbjct: 133 VHLDKN------------GNITVLGVFFKVGKENPELEKVWRV--MPEEPGQKRHLTARI 178 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 +P+ LLP +R Y+ Y GSLTTPP SE V WIV +EP+ +S Q+ KFR ++ Sbjct: 179 DPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVM--------- 229 Query: 242 HMVNNFRPPQPLKGRVV 258 +N RP QPL R V Sbjct: 230 -GFDNNRPVQPLNARKV 245 >4G7A-A nrPDB Length = 248 Score = 130 bits (326), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 90/263 (34%), Positives = 129/263 (49%), Gaps = 43/263 (16%) Query: 5 HGWGYGQDDGPSHWHKLYPI---AQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSI 61 H W Y + GP HW +L P + QSPINI V + +L L L Y+ + Sbjct: 24 HEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINIDKKYKVKA-NLPKLNLYYKTAKESEV 82 Query: 62 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELH 121 NNGH++Q++ + + T L Y+LKQFHFH SEHT++ KS+P E+H Sbjct: 83 VNNGHTIQINIKEDN-----TLNYLGEKYQLKQFHFH------TPSEHTIEKKSYPLEIH 131 Query: 122 LVHWNAKKYSTFGEAASAPDG-LAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180 VH DG + VVGV + G + ++++ + +G K Sbjct: 132 FVH-------------KTEDGKILVVGVMAKLGKTNKELDKILNV--APAEEGEKILDKN 176 Query: 181 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 N L+P + Y TY GSLTTPP +E V WIVL++PI IS++Q+ K +S+ Sbjct: 177 LNLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSV--------- 227 Query: 241 IHMVN-NFRPPQPLKGRVVKASF 262 MVN N RP Q + R + F Sbjct: 228 --MVNPNNRPVQEINSRWIIEGF 248 >6EKI-A nrPDB Length = 226 Score = 127 bits (318), Expect = 7e-30, Method: Compositional matrix adjust. Identities = 88/257 (34%), Positives = 129/257 (50%), Gaps = 45/257 (17%) Query: 7 WGYGQDDGPSHWHKL---YPIAQ-GDRQSPINIISSQAVYSPSLQPLELSYEACMSLSIT 62 W Y + GP HW L Y + + G QSP++I + L+ ++++Y + S SIT Sbjct: 6 WSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDI---SRIVEAELEKIKINYSSGGS-SIT 61 Query: 63 NNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 NNGH+++V + + +V G E LKQFHFH SEHT+ GKS+P E H Sbjct: 62 NNGHTIKVSY-EPGSYIIVDGIRFE----LKQFHFH------APSEHTIKGKSYPFEAHF 110 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFS-CF 181 VH A LAV+GV + G ++P + ++ + L G + + Sbjct: 111 VH------------ADKDGNLAVIGVIFKEGKKNPIIEKIWENLPEA---GKTIKLAHKI 155 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 N LLP + Y+ Y GSLTTPP SE V WIV+ E + +S+ Q+ KFR L+ + Sbjct: 156 NAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMGGDTN---- 211 Query: 242 HMVNNFRPPQPLKGRVV 258 RP QPL R++ Sbjct: 212 ------RPVQPLNARMI 222 >3ZNC-A nrPDB Length = 258 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 83/250 (33%), Positives = 128/250 (51%), Gaps = 17/250 (6%) Query: 14 GPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLEL-SYEACMSLSITNNGHSVQVDF 72 GP W + ++QSPINI++++ +P L P L Y+ I NN H+V++ Sbjct: 16 GPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQQWPIKNNQHTVEMTL 72 Query: 73 NDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYST 132 + GG L Y Q H HW +D GSEH++DG+ F E+H+VH KK ++ Sbjct: 73 GGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHIVH---KKLTS 126 Query: 133 FGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASR 191 E + D AV+ +E GD+ + L +AL + + + + + +LP S Sbjct: 127 SKE--DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTSTVRESSLQDMLPPST 184 Query: 192 H---YWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFR 248 Y+ Y GSLTTP E+V W V ++PI I + Q +F L+ E D++++M +N R Sbjct: 185 KMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLYYDE-DQKLNMKDNVR 243 Query: 249 PPQPLKGRVV 258 P QPL R V Sbjct: 244 PLQPLGKRQV 253 >5HPJ-A nrPDB Length = 217 Score = 123 bits (309), Expect = 6e-29, Method: Compositional matrix adjust. Identities = 90/255 (35%), Positives = 121/255 (47%), Gaps = 44/255 (17%) Query: 7 WGYGQDDGPSHWHKLYPI-AQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNG 65 W Y + G HW + A+G Q+PI+I + L PL L YE ++ + NNG Sbjct: 2 WSYTGEHGTEHWGDSFATCAEGVNQTPIDINQTTQA---ELAPLHLDYEGQVT-ELVNNG 57 Query: 66 HSVQVDFNDSDDRTVVTGGPLEGP-YRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 124 H++Q + + TV +G + LKQFHFH SE+ + GK +P E H VH Sbjct: 58 HTIQANLTGKNTLTV------DGKTFELKQFHFH------TPSENYLKGKQYPLEAHFVH 105 Query: 125 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQF-SCFNP 183 K GE LAVV V + G S N LT L + KG + NP Sbjct: 106 ATDK-----GE-------LAVVAVMFDFGPR--SNNELTTLLASIPSKGQTVELKEALNP 151 Query: 184 KCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHM 243 LLP R Y+ + GSLTTPP SE V W V++EP S+ Q K +++ M Sbjct: 152 ADLLPRDREYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQAV-----------M 200 Query: 244 VNNFRPPQPLKGRVV 258 NN RP QPL R++ Sbjct: 201 GNNARPLQPLNARLI 215 >1KOQ-A nrPDB Length = 223 Score = 113 bits (283), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 82/259 (31%), Positives = 120/259 (46%), Gaps = 42/259 (16%) Query: 4 HHGWGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSL 59 H WGY D P W L + G QSP+NI + S L ++++Y+ M + Sbjct: 1 HTHWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITET---VSGKLPAIKVNYKPSM-V 56 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSE 119 + NNGH++QV++ + + V G Y LKQFHFH V SE+ + G++FP E Sbjct: 57 DVENNGHTIQVNYPEGGNTLTVNGRT----YTLKQFHFH------VPSENQIKGRTFPME 106 Query: 120 LHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFS 179 H VH + K V+ V E G + ++ + + + M K Q Sbjct: 107 AHFVHLDENKQP------------LVLAVLYEAGKTNGRLSSIWNVMPMTAGKVKLNQ-- 152 Query: 180 CFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDE 239 F+ LLP Y+ + GSLTTPP +E V+W+VL+ I + Q KF + + Sbjct: 153 PFDASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSE---- 208 Query: 240 RIHMVNNFRPPQPLKGRVV 258 N RP QPL RVV Sbjct: 209 ------NNRPVQPLNARVV 221 >4XZ5-A nrPDB Length = 233 Score = 113 bits (283), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 76/231 (32%), Positives = 112/231 (48%), Gaps = 30/231 (12%) Query: 7 WGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSIT 62 WGY ++GP +W +L P G QSPIN+ AV + SL ++ Y +L + Sbjct: 4 WGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRET-ALKLI 62 Query: 63 NNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 NNGH++QV+ + G Y L Q+HFH SEH DG ++P E+HL Sbjct: 63 NNGHTLQVNI-PLGSYIKINGHR----YELLQYHFH------TPSEHQRDGFNYPMEMHL 111 Query: 123 VHWNAKKYSTFGEAASAPDG-LAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCF 181 VH + DG LAV+ + + G+E+ ++ +L L K + Sbjct: 112 VHKDG-------------DGNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKI 158 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLL 232 +P PA + ++ Y GSLTTPP SE V W+V ++PI S Q+ K L Sbjct: 159 HPAKFFPADKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYL 209 >4XIW-A nrPDB Length = 239 Score = 102 bits (255), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 84/264 (31%), Positives = 121/264 (45%), Gaps = 40/264 (15%) Query: 6 GWGYGQDDGPSHWHKLYPIAQGDRQSPINII--SSQAVYSPSLQPLELSYEACMSLSITN 63 W YG+ GP W + A G RQSPINI +S + + +Y + + N Sbjct: 3 AWNYGEVAGPPTWKGV--CATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFEKCDVLN 60 Query: 64 NGH-SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 GH ++QV+F + + G +E L QFHFH SEH +DG+ + E HL Sbjct: 61 TGHGTMQVNFPAGNLAFI---GNME--LELLQFHFH------APSEHAMDGRRYAMEAHL 109 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQFSC 180 VH N + LAV+G+ LE G ++P+++ + V K Sbjct: 110 VHKN-----------KSTGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPL-AKKPSPKG 157 Query: 181 FNPKCLLP-----ASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS 235 NP LLP +R + YPGSLTTPP SE V W V +PI + + Q+ F + Sbjct: 158 INPVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFV--- 214 Query: 236 EDDERIHMVNNFRPPQPLKGRVVK 259 D + + N RP Q L R+V+ Sbjct: 215 -GDNKTYATNT-RPLQLLNSRLVE 236 >4TWL-A nrPDB Length = 246 Score = 93.2 bits (230), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/256 (28%), Positives = 113/256 (44%), Gaps = 39/256 (15%) Query: 10 GQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNG 65 G +GP +W L P +G QSPI + ++ ++ +L L +Y A + + N+G Sbjct: 10 GNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYRA-VDARLRNSG 68 Query: 66 HSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHW 125 H V VDF + + Y+LK+ HFH SEH ++G+ F E LVH Sbjct: 69 HDVLVDFKGNAGSLSIN----RVEYQLKRIHFH------SPSEHEMNGERFDLEAQLVH- 117 Query: 126 NAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQ---FSCFN 182 S AVV + G P ++ L D ++ +F ++ + Sbjct: 118 -----------ESQDQKRAVVSILFRFGRADPFLSDLED--FIKQFSNSQKNEINAGVVD 164 Query: 183 PKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIH 242 P L Y+ Y GS T PP +E ++W V+R+ +S RQ+ LL +E + Sbjct: 165 PNQLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQV-----LLLKQAVNE--N 217 Query: 243 MVNNFRPPQPLKGRVV 258 +NN RP QP R V Sbjct: 218 AINNARPLQPTNFRSV 233 >5TT3-A nrPDB Length = 234 Score = 79.3 bits (194), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 66/260 (25%), Positives = 107/260 (41%), Gaps = 45/260 (17%) Query: 7 WGY-GQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSI 61 W Y +++GP W KL+ G QSPINI ++ L+ Y A ++ Sbjct: 10 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINI--EHYYHTQDKADLQFKYAASKPKAV 67 Query: 62 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELH 121 H+++ F ++ Y L HFH E ++ K+ P H Sbjct: 68 FFTHHTLKASFEPTNHINYRGHD-----YVLDNVHFH------APMEFLINNKTRPLSAH 116 Query: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCF 181 VH +AK L V+ + E G E+P+++ + + + K F Sbjct: 117 FVHKDAK------------GRLLVLAIGFEEGKENPNLDPILEGI------QKKQNFKEV 158 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 LP S +Y+ + GSLT PP +E V W V+ EP+ +S +Q+ + + +R+ Sbjct: 159 ALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIK---------KRM 209 Query: 242 HMVNNFRPPQPLKGRVVKAS 261 N RP QP V+ S Sbjct: 210 KNSPNQRPVQPDYNTVIIKS 229 >3B1B-A nrPDB Length = 377 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 76/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%) Query: 27 GDRQSPINIISSQAV------YSPSLQPLELSYEACMS----LSITNNGHSVQVDF---- 72 G +QSPIN+ Q + + LQ + SY MS + + NNGH++QV + Sbjct: 64 GRKQSPINVPQYQVLDGKGSKIANGLQ-TQWSYPDLMSNGTSVQVINNGHTIQVQWTYNY 122 Query: 73 --------------------------NDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVG 106 ND+ DR VT P QFHFH Sbjct: 123 AGHATIAIPAMHNQTNRIVDVLEMRPNDAADR--VTAVP-------TQFHFH------ST 167 Query: 107 SEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDAL 166 SEH + GK +P ELH+VH +K A +V G+ + D P N L + + Sbjct: 168 SEHLLAGKIYPLELHIVHQVTEKLE-----ACKGGCFSVTGILFQL-DNGPD-NELLEPI 220 Query: 167 Y--MVRFKGTKAQF---SCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICIS 221 + M +GT + + LLP+ R Y TY GSLTTPP SE + W V+ +P IS Sbjct: 221 FANMPSREGTFSNLPAGTTIKLGELLPSDRDYVTYEGSLTTPPCSEGLLWHVMTQPQRIS 280 Query: 222 ERQMGKFR 229 Q ++R Sbjct: 281 FGQWNRYR 288 >3Q31-A nrPDB Length = 244 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 69/231 (29%), Positives = 98/231 (42%), Gaps = 40/231 (17%) Query: 14 GPSHWHKL----YPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQ 69 GP +W+ L A+G QSPI +I S A+ + L+L + N G +Q Sbjct: 18 GPLNWYGLDEANEACAKGKHQSPI-VIDSAAIDYAASGSLKLDLPLADGSKLENLGFGLQ 76 Query: 70 VDFNDSDDRTVVTGGPLEG---PYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 V +T G L Y L QFHFH +H V EH FP E+H V Sbjct: 77 V---------TLTNGSLTANSKTYTLAQFHFHTPSEHHVNEEH------FPMEVHFVFQT 121 Query: 127 AKKYSTFGEAASAPDGLAVVGVFL---ETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNP 183 A K + AVVG F E GD P + + + + GT + Sbjct: 122 AAKET------------AVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGTSTTTGQLDF 169 Query: 184 KCLLP-ASRH-YWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLL 232 LL +RH + Y GSLTTPP +E V W + EP+ ++ + K + ++ Sbjct: 170 GGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKII 220 >1Y7W-A nrPDB Length = 291 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 78/261 (29%), Positives = 108/261 (41%), Gaps = 41/261 (15%) Query: 22 YPIAQGDRQSPINIISSQ--------AVYSPSLQPLELSYEACMSLSITN------NGHS 67 YP G QSPI+I ++Q + SL L + +++TN G Sbjct: 43 YPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLTNAKVDLEQGMK 102 Query: 68 VQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNA 127 V D ++ T+ GG + + QFHFH H + SEHT++G +P ELH+V Sbjct: 103 VTFDQPAANLPTIEIGGTTK-SFVPIQFHFH----HFL-SEHTINGIHYPLELHIVMQEQ 156 Query: 128 KKYSTFGEAASAPDGLAVVGV---FLETGDEHPSMNRLTDALY------MVRFKGTKAQF 178 A A LAV+G+ + E GD +N L + + T Sbjct: 157 DP------ADVATAQLAVIGIMYKYSENGDAF--LNSLQTQIEGKIGDGTASYGDTGVSI 208 Query: 179 SCFNPKC-LLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSED 237 N K LLP+S Y Y GSLTTP E V W V P ++ QM F + + Sbjct: 209 DNINVKTQLLPSSLKYAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKLFVDVTMGAHA 268 Query: 238 DERIHMVNNFRPPQPLKGRVV 258 + VNN R Q L R V Sbjct: 269 GADV--VNN-RMIQDLGDREV 286 >6HIV-DP nrPDB Length = 274 Score = 27.7 bits (60), Expect = 4.8, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 1/92 (1%) Query: 101 KKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETG-DEHPSM 159 KK + + +DG P E +++ W+ K +S G PD L +E D ++ Sbjct: 73 KKRHMLRKERLDGPETPLEKYVLEWHKKFHSFQGTERPTPDDLHTALDLVERPLDLSYAL 132 Query: 160 NRLTDALYMVRFKGTKAQFSCFNPKCLLPASR 191 L + + K F F CL R Sbjct: 133 QLLGQCRNLNNIRFAKETFLVFLEACLRVGRR 164 >4POR-A nrPDB Length = 278 Score = 27.7 bits (60), Expect = 5.3, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 7/41 (17%) Query: 190 SRHYWTYPGSLTTPPL---SESVTWIVLRE----PICISER 223 +R+Y ++ G TTPP+ + SVT ++L E P+C ++ Sbjct: 196 TRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDK 236 >4MBZ-A nrPDB Length = 278 Score = 27.7 bits (60), Expect = 5.9, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 25/41 (60%), Gaps = 7/41 (17%) Query: 190 SRHYWTYPGSLTTPPL---SESVTWIVLRE----PICISER 223 +R+Y ++ G TTPP+ + SVT ++L E P+C ++ Sbjct: 196 TRYYGSFTGGATTPPVMQFTNSVTTVLLDENGVGPLCKGDK 236 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6G4T-A nrPDB 407 e-114 4CNR-A nrPDB 376 e-105 1FLJ-A nrPDB 375 e-104 1Z93-A nrPDB 375 e-104 4QK3-A nrPDB 372 e-103 3D0N-A nrPDB 364 e-101 6FAF-A nrPDB 363 e-101 1URT-A nrPDB 337 3e-93 1RJ5-A nrPDB 307 3e-84 4LU3-A nrPDB 306 5e-84 2W2J-A nrPDB 303 5e-83 5LL9-A nrPDB 286 4e-78 5DVX-A nrPDB 283 5e-77 4COQ-A nrPDB 278 2e-75 5JN8-A nrPDB 277 3e-75 3ZNC-A nrPDB 272 9e-74 4X5S-A nrPDB 271 3e-73 3FE4-A nrPDB 270 5e-73 6EKI-A nrPDB 258 1e-69 4G7A-A nrPDB 256 7e-69 1KOQ-A nrPDB 248 3e-66 4XZ5-A nrPDB 247 4e-66 5HPJ-A nrPDB 242 1e-64 4ETQ-X nrPDB 239 9e-64 4XIW-A nrPDB 237 4e-63 6B9J-X nrPDB 236 7e-63 4TWL-A nrPDB 225 2e-59 5TT3-A nrPDB 209 1e-54 1Y7W-A nrPDB 201 3e-52 3Q31-A nrPDB 192 1e-49 3B1B-A nrPDB 179 1e-45 Sequences not found previously or not previously below threshold: 5KST-A nrPDB 30 0.83 1S7T-A nrPDB 30 0.87 5TTH-B nrPDB 30 1.5 4GF1-A nrPDB 29 1.8 1PQ3-A nrPDB 29 2.1 4OKD-A nrPDB 28 5.0 CONVERGED! >6G4T-A nrPDB Length = 274 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 262/264 (99%), Positives = 262/264 (99%) Query: 1 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS 60 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS Sbjct: 3 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS 62 Query: 61 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 120 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL Sbjct: 63 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 122 Query: 121 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC Sbjct: 123 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 182 Query: 181 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 FNPK LLPASRHYWTYPGSLTTPPLSESVTWIVLREPI ISERQMGKFRSLLFTSEDDER Sbjct: 183 FNPKSLLPASRHYWTYPGSLTTPPLSESVTWIVLREPISISERQMGKFRSLLFTSEDDER 242 Query: 241 IHMVNNFRPPQPLKGRVVKASFRA 264 IHMVNNFRPPQPLKGRVVKASFRA Sbjct: 243 IHMVNNFRPPQPLKGRVVKASFRA 266 >4CNR-A nrPDB Length = 262 Score = 376 bits (965), Expect = e-105, Method: Composition-based stats. Identities = 142/259 (54%), Positives = 178/259 (68%), Gaps = 1/259 (0%) Query: 1 MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS 60 M H WGY + +GP HWHK +PIA G+RQSP++I + V P+L+PL L Y S Sbjct: 1 MGMSHHWGYDKHNGPEHWHKDFPIANGERQSPVDIDTDAVVQDPALKPLALDYGEATSRR 60 Query: 61 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL 120 + N+GHS V+++DS D+ V+ GPL G YRL QFHFHWG D GSEHTVD K + +EL Sbjct: 61 MVNDGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAEL 120 Query: 121 HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180 HLVHWN KY FG AA PDGLAVVGVFL+ GD +P++ ++ DAL ++ KG F Sbjct: 121 HLVHWNT-KYGDFGTAAQEPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPN 179 Query: 181 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 F+P LLP YWTYPGSLTTPPL ESVTWIVL+EPI +S +QM KFR+L F +E + Sbjct: 180 FDPGSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPE 239 Query: 241 IHMVNNFRPPQPLKGRVVK 259 M+ N+RP QPLK R V+ Sbjct: 240 ELMLANWRPAQPLKNRQVR 258 >1FLJ-A nrPDB Length = 260 Score = 375 bits (963), Expect = e-104, Method: Composition-based stats. Identities = 138/258 (53%), Positives = 183/258 (70%), Gaps = 1/258 (0%) Query: 6 GWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNG 65 WGY +GP HWH+LYPIA+GD QSPI + + + PSLQP +SY+ + +I NNG Sbjct: 4 EWGYASHNGPEHWHELYPIAKGDNQSPIELHTKDIRHDPSLQPWSVSYDPGSAKTILNNG 63 Query: 66 HSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHW 125 + +V F+D+ DR+++ GGPL GPYRL+QFH HWG D GSEHTVDG + +ELHLVHW Sbjct: 64 KTCRVVFDDTFDRSMLRGGPLSGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHW 123 Query: 126 NAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKC 185 N KY+TFGEA PDG+AVVG+FL+ G E L DAL ++ KG +A F+ F+P C Sbjct: 124 NP-KYNTFGEALKQPDGIAVVGIFLKIGREKGEFQILLDALDKIKTKGKEAPFNHFDPSC 182 Query: 186 LLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVN 245 L PA R YWTY GS TTPP E + W++L+EP+ +S QM K RSL ++E++ + +V Sbjct: 183 LFPACRDYWTYHGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLFASAENEPPVPLVG 242 Query: 246 NFRPPQPLKGRVVKASFR 263 N+RPPQP+KGRVV+ASF+ Sbjct: 243 NWRPPQPIKGRVVRASFK 260 >1Z93-A nrPDB Length = 266 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 130/261 (49%), Positives = 180/261 (68%), Gaps = 1/261 (0%) Query: 3 GHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSIT 62 WGY +GP HWH+L+P A+G+ QSPI + + + PSLQP +SY+ + +I Sbjct: 1 MAKEWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTIL 60 Query: 63 NNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 NNG + +V F+D+ DR+++ GGPL GPYRL+QFH HWG D GSEHTVDG + +ELHL Sbjct: 61 NNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFN 182 VHWN KY+TF EA DG+AV+G+FL+ G E+ DAL ++ KG +A F+ F+ Sbjct: 121 VHWNP-KYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFD 179 Query: 183 PKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIH 242 P L PASR YWTY GS TTPP E + W++L+EP+ +S QM K RSLL ++E++ + Sbjct: 180 PSSLFPASRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVP 239 Query: 243 MVNNFRPPQPLKGRVVKASFR 263 +V+N+RPPQP+ RVV+ASF+ Sbjct: 240 LVSNWRPPQPINNRVVRASFK 260 >4QK3-A nrPDB Length = 249 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 144/261 (55%), Positives = 182/261 (69%), Gaps = 12/261 (4%) Query: 3 GHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSIT 62 H WGYG+ +GP HWHK +PIA+G+RQSP++I + A Y PSL+PL +SY+ SL I Sbjct: 1 MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL 60 Query: 63 NNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 NNGH+ V+F+DS D+ V+ GGPL+G YRL QFHFHWG GSEHTVD K + +ELHL Sbjct: 61 NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFN 182 VHWN KY FG+A PDGLAV+G+FL+ G P + ++ D L ++ KG A F+ F+ Sbjct: 121 VHWNT-KYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179 Query: 183 PKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIH 242 P+ LLP S YWTYPGSLTTPPL E VTWIVL+EPI +S Q+ KFR L Sbjct: 180 PRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKL----------- 228 Query: 243 MVNNFRPPQPLKGRVVKASFR 263 MV+N+RP QPLK R +KASF+ Sbjct: 229 MVDNWRPAQPLKNRQIKASFK 249 >3D0N-A nrPDB Length = 264 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 138/256 (53%), Positives = 186/256 (72%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66 WGY + +GP HW + +PIA GD+QSPI I + + Y SL+PL + Y+ + I+N+GH Sbjct: 8 WGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGH 67 Query: 67 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 S VDF+D+++++V+ GGPL G YRL+Q H HWG D GSEH VDG S+ +ELH+VHWN Sbjct: 68 SFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWN 127 Query: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186 + KY +F EAA PDGLAV+GVFL+ G+ + + ++TD L ++ KG + +F+ F+ L Sbjct: 128 SDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSL 187 Query: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246 LP S YWTYPGSLT PPL ESVTWIVL++PI IS +Q+ KFRSLL T+E + +V+N Sbjct: 188 LPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSN 247 Query: 247 FRPPQPLKGRVVKASF 262 RPPQPLKGR V+ASF Sbjct: 248 HRPPQPLKGRKVRASF 263 >6FAF-A nrPDB Length = 261 Score = 363 bits (931), Expect = e-101, Method: Composition-based stats. Identities = 132/256 (51%), Positives = 178/256 (69%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGH 66 WGY +GP W KLYPIA G+ QSP++I +S+ + SL+P+ +SY + I N GH Sbjct: 6 WGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGH 65 Query: 67 SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWN 126 S V+F D+D+R+V+ GGP YRL QFHFHWG ++ GSEHTVDG + +ELH+ HWN Sbjct: 66 SFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWN 125 Query: 127 AKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186 + KYS+ EAAS DGLAV+GV ++ G+ +P + ++ DAL ++ KG +A F+ F+P L Sbjct: 126 SAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTL 185 Query: 187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNN 246 LP+S +WTYPGSLT PPL ESVTWI+ +E I +S Q+ +FRSLL E D + M +N Sbjct: 186 LPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHN 245 Query: 247 FRPPQPLKGRVVKASF 262 RP QPLKGR V+ASF Sbjct: 246 NRPTQPLKGRTVRASF 261 >1URT-A nrPDB Length = 248 Score = 337 bits (864), Expect = 3e-93, Method: Composition-based stats. Identities = 126/239 (52%), Positives = 168/239 (70%) Query: 25 AQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGG 84 A+G RQSPINI +VY P L PL +SY+A + N GH+ QV+F+DS + + ++GG Sbjct: 2 AEGTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGHAFQVEFDDSCEDSGISGG 61 Query: 85 PLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLA 144 PL YRLKQFHFHWG + GSEH VDG ++P+ELHLVHWN+ KY + +A+ +GLA Sbjct: 62 PLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWNSTKYENYKKASVGENGLA 121 Query: 145 VVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPP 204 V+GVFL+ G H ++ +L D L VR K T+ F+P CL+PA R YWTYPGSLTTPP Sbjct: 122 VIGVFLKLGAHHQALQKLVDVLPEVRHKDTQVAMGDFDPSCLMPACRDYWTYPGSLTTPP 181 Query: 205 LSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFR 263 L+ESVTWIV + P+ +S Q+ FR+LLF+ +E MVNN+RP QPL+ R +++SFR Sbjct: 182 LAESVTWIVQKTPVEVSPSQLSMFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR 240 >1RJ5-A nrPDB Length = 261 Score = 307 bits (787), Expect = 3e-84, Method: Composition-based stats. Identities = 97/266 (36%), Positives = 142/266 (53%), Gaps = 11/266 (4%) Query: 3 GHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSL---QPLELSYEACMSL 59 G H W Y G HW YP GD QSPINI + ++ P L QP L Sbjct: 1 GGHHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGYDQLGTEPL 60 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDV-GSEHTVDGKSFPS 118 + NNGH+VQ+ + G L Y Q H HWG++ + GSEH ++ ++ + Sbjct: 61 DLHNNGHTVQLSLPPTLHL-----GGLPRKYTAAQLHLHWGQRGSLEGSEHHINSEATAA 115 Query: 119 ELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD-EHPSMNRLTDALYMVRFKGTKAQ 177 ELH+VH++++ YS+ EAA P GLAV+G+ +E G+ E+P+ + + L+ +R+K K Sbjct: 116 ELHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGETENPAYDHILSRLHEIRYKDQKTS 175 Query: 178 FSCFNPKCLLPASRH-YWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSE 236 F+ + L P ++ Y GSLTTPP +SV W V IS Q+ K + L ++E Sbjct: 176 VPPFSVRELFPQQLEQFFRYNGSLTTPPCYQSVLWTVFNRRAQISMGQLEKLQETLSSTE 235 Query: 237 DDERIHMVNNFRPPQPLKGRVVKASF 262 +D +V N+R PQPL R + ASF Sbjct: 236 EDPSEPLVQNYRVPQPLNQRTIFASF 261 >4LU3-A nrPDB Length = 279 Score = 306 bits (785), Expect = 5e-84, Method: Composition-based stats. Identities = 95/266 (35%), Positives = 137/266 (51%), Gaps = 11/266 (4%) Query: 3 GHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSP---SLQPLELSYEACMSL 59 G W Y G HW YP + QSPI+I + + P +LQP L Sbjct: 3 GGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPL 62 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVG-SEHTVDGKSFPS 118 + NNGH+VQ+ + + G L Y Q H HWG+K G SEH ++ ++ + Sbjct: 63 DLHNNGHTVQLSLP-----STLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFA 117 Query: 119 ELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD-EHPSMNRLTDALYMVRFKGTKAQ 177 ELH+VH+++ Y + EAA P GLAV+G+ +E G+ ++ + + L+ VR K K Sbjct: 118 ELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTS 177 Query: 178 FSCFNPKCLLPASR-HYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSE 236 FN + LLP Y+ Y GSLTTPP +SV W V IS Q+ K + LF++E Sbjct: 178 VPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTE 237 Query: 237 DDERIHMVNNFRPPQPLKGRVVKASF 262 ++ +V N+R QPL R+V ASF Sbjct: 238 EEPSKLLVQNYRALQPLNQRMVFASF 263 >2W2J-A nrPDB Length = 291 Score = 303 bits (776), Expect = 5e-83, Method: Composition-based stats. Identities = 106/258 (41%), Positives = 157/258 (60%), Gaps = 14/258 (5%) Query: 17 HWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLEL--SYEACMSLSITNNGHSVQVDFND 74 W ++P A G+ QSPIN+ S +A Y PSL + L +Y C +TN+GH++QV Sbjct: 37 EWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS 96 Query: 75 SDDRTVVTGGPLEG--PYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYST 132 ++V++GGPL + L + FHWG+++ GSEHTV+ K+FP ELHL+HWN+ + + Sbjct: 97 ---KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGS 153 Query: 133 FGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPA--S 190 EA P G+A++ +F++ G EH + +T+ L +++KG CFNP LLP Sbjct: 154 IDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLL 213 Query: 191 RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIH-----MVN 245 R YW Y GSLT PP SE VTWI+ R P+ IS+ Q+ +FR L + E + + + Sbjct: 214 RDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGD 273 Query: 246 NFRPPQPLKGRVVKASFR 263 NFRP QPL RV++A+F+ Sbjct: 274 NFRPTQPLSDRVIRAAFQ 291 >5LL9-A nrPDB Length = 263 Score = 286 bits (733), Expect = 4e-78, Method: Composition-based stats. Identities = 100/263 (38%), Positives = 140/263 (53%), Gaps = 12/263 (4%) Query: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLEL---SYEACMSLSITN 63 W Y DG + W K YP G QSPI++ S Y SL PLE + A +TN Sbjct: 4 WTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFLLTN 63 Query: 64 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHD-VGSEHTVDGKSFPSELHL 122 NGHSV+++ L+ Y Q H HWG +D GSEHTV G+ F +ELH+ Sbjct: 64 NGHSVKLNLPSDMHIQ-----GLQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHI 118 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFN 182 VH+N+ Y A++ +GLAV+ V +E G +PS +++ L V++KG +A FN Sbjct: 119 VHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPGFN 178 Query: 183 PKCLLP-ASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDD--E 239 + LLP + Y+ Y GSLTTPP + +V W V R P+ IS+ Q+ + L+ + D Sbjct: 179 IEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQEQLLALETALYCTHMDDPS 238 Query: 240 RIHMVNNFRPPQPLKGRVVKASF 262 M+NNFR Q R+V SF Sbjct: 239 PREMINNFRQVQKFDERLVYTSF 261 >5DVX-A nrPDB Length = 260 Score = 283 bits (724), Expect = 5e-77, Method: Composition-based stats. Identities = 100/264 (37%), Positives = 141/264 (53%), Gaps = 16/264 (6%) Query: 6 GWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS---YEACMSLSIT 62 W YG D W ++ P G QSP++I A +SP+L+PLELS L + Sbjct: 1 HWRYGGD---PPWPRVSPACAGRFQSPVDIRPQLAAFSPALRPLELSGFQLPPLPELRLR 57 Query: 63 NNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 NNGHSVQ+ + + G YR Q H HWG GSEHTV+G FP+E+H+ Sbjct: 58 NNGHSVQLTLPPGLEMKLGPG----REYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHV 113 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETG-DEHPSMNRLTDALYMVRFKGTKAQFSCF 181 VH + KY+ EA P GLAV+ FLE G +E+ + +L L + +G++ Q Sbjct: 114 VHL-STKYARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGL 172 Query: 182 NPKCLLPAS-RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 + LLP+ Y+ Y GSLTTPP ++ V W V + + +S +Q+ L+ D R Sbjct: 173 DISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVSLSAKQLHTLSDTLWG-PGDSR 231 Query: 241 IHMVNNFRPPQPLKGRVVKASFRA 264 + + NFR QPL GRV++ASF A Sbjct: 232 LQL--NFRATQPLNGRVIEASFPA 253 >4COQ-A nrPDB Length = 247 Score = 278 bits (711), Expect = 2e-75, Method: Composition-based stats. Identities = 92/260 (35%), Positives = 125/260 (48%), Gaps = 42/260 (16%) Query: 6 GWGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSI 61 WGY GP HW L P G QSPI+I S+ AV L P+ + Y + + Sbjct: 25 HWGYSGSIGPEHWGDLSPEYLMCKIGKNQSPIDINSADAVK-ACLAPVSVYY-VSDAKYV 82 Query: 62 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELH 121 NNGH+++V VV G + LKQFHFH SEHTV+GK +P E H Sbjct: 83 VNNGHTIKVVMGGRG-YVVVDG----KRFYLKQFHFH------APSEHTVNGKHYPFEAH 131 Query: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC- 180 VH + + V+GVF + G E+P + ++ + G K + Sbjct: 132 FVHLDKN------------GNITVLGVFFKVGKENPELEKVWRVMPE--EPGQKRHLTAR 177 Query: 181 FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240 +P+ LLP +R Y+ Y GSLTTPP SE V WIV +EP+ +S Q+ KFR ++ Sbjct: 178 IDPEKLLPENRDYYRYSGSLTTPPCSEGVRWIVFKEPVEMSREQLEKFRKVMG------- 230 Query: 241 IHMVNNFRPPQPLKGRVVKA 260 +N RP QPL R V Sbjct: 231 ---FDNNRPVQPLNARKVMK 247 >5JN8-A nrPDB Length = 266 Score = 277 bits (709), Expect = 3e-75, Method: Composition-based stats. Identities = 90/267 (33%), Positives = 130/267 (48%), Gaps = 15/267 (5%) Query: 6 GWGYGQDDGPSHWHKLYPI-----AQGDRQSPINIISSQAVYSPSLQPLELS-YEACMSL 59 W Y S++ L P+ Q DRQSPINI++++A L S Y+ + Sbjct: 4 HWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTW 63 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSE 119 ++ NNGHSV + ++ ++GG L PY+ KQ H HW GSEH++DG+ F E Sbjct: 64 TVQNNGHSVMMLLE---NKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAME 120 Query: 120 LHLVHWNAKKYS-TFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMVRFKGTKAQ 177 +H+VH K S EA D +AV+ +E G + + L +AL + Sbjct: 121 MHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTT 180 Query: 178 FSCFNPKCLLPAS---RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFT 234 + + LLP RHY+ Y GSLTTP E V W V REPI + Q+ F L+ Sbjct: 181 MAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYY 240 Query: 235 SEDDERIHMVNNFRPPQPLKGRVVKAS 261 + ++ + M +N RP Q L R V S Sbjct: 241 DK-EQTVSMKDNVRPLQQLGQRTVIKS 266 >3ZNC-A nrPDB Length = 258 Score = 272 bits (696), Expect = 9e-74, Method: Composition-based stats. Identities = 85/268 (31%), Positives = 131/268 (48%), Gaps = 25/268 (9%) Query: 7 WGYGQDD--------GPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLE-LSYEACM 57 W Y GP W + ++QSPINI++++ +P L P + Y+ Sbjct: 1 WCYEIQTEDPRSSCLGPEKWPG---ACKENQQSPINIVTARTKVNPRLTPFILVGYDQKQ 57 Query: 58 SLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFP 117 I NN H+V++ + GG L Y Q H HW +D GSEH++DG+ F Sbjct: 58 QWPIKNNQHTVEMTLGGG---ACIIGGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFA 114 Query: 118 SELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALYMVRFKGTKA 176 E+H+VH KK ++ E + D AV+ +E GD+ + L +AL + + + Sbjct: 115 MEMHIVH---KKLTSSKE--DSKDKFAVLAFMIEVGDKVNKGFQPLVEALPSISKPHSTS 169 Query: 177 QFSCFNPKCLLPASRH---YWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLF 233 + + +LP S Y+ Y GSLTTP E+V W V ++PI I + Q +F L+ Sbjct: 170 TVRESSLQDMLPPSTKMYTYFRYNGSLTTPNCDETVIWTVYKQPIKIHKNQFLEFSKNLY 229 Query: 234 TSEDDERIHMVNNFRPPQPLKGRVVKAS 261 E D++++M +N RP QPL R V S Sbjct: 230 YDE-DQKLNMKDNVRPLQPLGKRQVFKS 256 >4X5S-A nrPDB Length = 232 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 91/264 (34%), Positives = 139/264 (52%), Gaps = 39/264 (14%) Query: 1 MTGHHGWGYGQDDGPSHWHKLYPI---AQGDRQSPINIISSQAVYSPSLQPLELSYEACM 57 M H W Y ++GP +W KL P QSP++I + V+ L+ L ++Y + Sbjct: 4 MAEVHHWSYEGENGPENWAKLNPEYFWCNLKNQSPVDISDNYKVH-AKLEKLHINYNKAV 62 Query: 58 SLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFP 117 + I NNGH++QV+ + D + + G Y LKQFHFH SEHTV+GK +P Sbjct: 63 NPEIVNNGHTIQVNVLE-DFKLNIKG----KEYHLKQFHFH------APSEHTVNGKYYP 111 Query: 118 SELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQ 177 E+HLVH + +AV+GVF + G +P ++++ ++ +G+K Sbjct: 112 LEMHLVHKD------------KDGNIAVIGVFFKEGKANPELDKVFKN--ALKEEGSKVF 157 Query: 178 FSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSED 237 N LLP ++Y+TY GSLTTPP +E V WIVL++PI S++Q+ F+S++ Sbjct: 158 DGSININALLPPVKNYYTYSGSLTTPPCTEGVLWIVLKQPITASKQQIELFKSIMKH--- 214 Query: 238 DERIHMVNNFRPPQPLKGRVVKAS 261 NN RP QP+ R + S Sbjct: 215 -------NNNRPTQPINSRYILES 231 >3FE4-A nrPDB Length = 278 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 97/265 (36%), Positives = 146/265 (55%), Gaps = 16/265 (6%) Query: 7 WGY-GQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS-YE-ACMSLSITN 63 W Y +HW + YP G RQSPIN+ ++ Y+PSL+ L ++ YE + N Sbjct: 4 WTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVN 63 Query: 64 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWG--KKHDVGSEHTVDGKSFPSELH 121 NGH+VQ+ + TV G Y +Q HFHWG GSEHTVDG E+H Sbjct: 64 NGHTVQISLPSTMRMTVADGTV----YIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 119 Query: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQFS 179 +VH+N+ KY ++ A APDGLAV+ F+E + E+ + L +++ G + + Sbjct: 120 IVHYNS-KYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 178 Query: 180 CFNPKCLLPASR-HYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDD 238 + + +LP + HY+TY GSLTTPP +E+V W VL + + +S Q+ K + L + Sbjct: 179 GLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLL-DHRN 237 Query: 239 ERIHMVNNFRPPQPLKGRVVKASFR 263 + IH N++R QPL RVV+++F Sbjct: 238 KTIH--NDYRRTQPLNHRVVESNFP 260 >6EKI-A nrPDB Length = 226 Score = 258 bits (660), Expect = 1e-69, Method: Composition-based stats. Identities = 87/264 (32%), Positives = 128/264 (48%), Gaps = 45/264 (17%) Query: 2 TGHHGWGYGQDDGPSHWHKL---YPIAQ-GDRQSPINIISSQAVYSPSLQPLELSYEACM 57 G W Y + GP HW L Y + + G QSP++I + L+ ++++Y + Sbjct: 1 GGVGHWSYHGETGPQHWGDLKNEYIMCKIGKNQSPVDI---SRIVEAELEKIKINY-SSG 56 Query: 58 SLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFP 117 SITNNGH+++V + +V G + LKQFHFH SEHT+ GKS+P Sbjct: 57 GSSITNNGHTIKVSYEPG-SYIIVDG----IRFELKQFHFH------APSEHTIKGKSYP 105 Query: 118 SELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQ 177 E H VH A LAV+GV + G ++P + ++ + L G + Sbjct: 106 FEAHFVH------------ADKDGNLAVIGVIFKEGKKNPIIEKIWENLPE---AGKTIK 150 Query: 178 FS-CFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSE 236 + N LLP + Y+ Y GSLTTPP SE V WIV+ E + +S+ Q+ KFR L+ Sbjct: 151 LAHKINAYDLLPKKKKYYRYSGSLTTPPCSEGVRWIVMEEEMELSKEQIEKFRKLMGG-- 208 Query: 237 DDERIHMVNNFRPPQPLKGRVVKA 260 + RP QPL R++ Sbjct: 209 --------DTNRPVQPLNARMIME 224 >4G7A-A nrPDB Length = 248 Score = 256 bits (654), Expect = 7e-69, Method: Composition-based stats. Identities = 83/261 (31%), Positives = 123/261 (47%), Gaps = 39/261 (14%) Query: 5 HGWGYGQDDGPSHWHKLYPI---AQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSI 61 H W Y + GP HW +L P + QSPINI + +L L L Y+ + Sbjct: 24 HEWSYEGEKGPEHWAQLKPEFFWCKLKNQSPINI-DKKYKVKANLPKLNLYYKTAKESEV 82 Query: 62 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELH 121 NNGH++Q++ + + L Y+LKQFHFH SEHT++ KS+P E+H Sbjct: 83 VNNGHTIQINIKEDNTLNY-----LGEKYQLKQFHFH------TPSEHTIEKKSYPLEIH 131 Query: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCF 181 VH + VVGV + G + ++++ + +G K Sbjct: 132 FVHKTED------------GKILVVGVMAKLGKTNKELDKILNVAP--AEEGEKILDKNL 177 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 N L+P + Y TY GSLTTPP +E V WIVL++PI IS++Q+ K +S++ Sbjct: 178 NLNNLIPKDKRYMTYSGSLTTPPCTEGVRWIVLKKPISISKQQLEKLKSVMVN------- 230 Query: 242 HMVNNFRPPQPLKGRVVKASF 262 N RP Q + R + F Sbjct: 231 ---PNNRPVQEINSRWIIEGF 248 >1KOQ-A nrPDB Length = 223 Score = 248 bits (632), Expect = 3e-66, Method: Composition-based stats. Identities = 82/261 (31%), Positives = 120/261 (45%), Gaps = 42/261 (16%) Query: 4 HHGWGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSL 59 H WGY D P W L + G QSP+NI + S L ++++Y+ M + Sbjct: 1 HTHWGYTGHDSPESWGNLSEEFRLCSTGKNQSPVNITET---VSGKLPAIKVNYKPSM-V 56 Query: 60 SITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSE 119 + NNGH++QV++ + + V G Y LKQFHFH V SE+ + G++FP E Sbjct: 57 DVENNGHTIQVNYPEGGNTLTVNG----RTYTLKQFHFH------VPSENQIKGRTFPME 106 Query: 120 LHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFS 179 H VH + K V+ V E G + ++ + + + M K Q Sbjct: 107 AHFVHLDENKQP------------LVLAVLYEAGKTNGRLSSIWNVMPMTAGKVKLNQ-- 152 Query: 180 CFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDE 239 F+ LLP Y+ + GSLTTPP +E V+W+VL+ I + Q KF + + Sbjct: 153 PFDASTLLPKRLKYYRFAGSLTTPPCTEGVSWLVLKTYDHIDQAQAEKFTRAVGSE---- 208 Query: 240 RIHMVNNFRPPQPLKGRVVKA 260 N RP QPL RVV Sbjct: 209 ------NNRPVQPLNARVVIE 223 >4XZ5-A nrPDB Length = 233 Score = 247 bits (630), Expect = 4e-66, Method: Composition-based stats. Identities = 80/262 (30%), Positives = 119/262 (45%), Gaps = 39/262 (14%) Query: 6 GWGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSI 61 WGY ++GP +W +L P G QSPIN+ AV + SL ++ Y +L + Sbjct: 3 HWGYFGEEGPQYWGELAPEFSTCKTGKNQSPINLKPQTAVGTTSLPGFDVYYRET-ALKL 61 Query: 62 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELH 121 NNGH++QV+ + G Y L Q+HFH SEH DG ++P E+H Sbjct: 62 INNGHTLQVNIP-LGSYIKINGH----RYELLQYHFH------TPSEHQRDGFNYPMEMH 110 Query: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCF 181 LVH + LAV+ + + G+E+ ++ +L L K + Sbjct: 111 LVHKDGD------------GNLAVIAILFQEGEENETLAKLMSFLPQTLKKQEIHESVKI 158 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 +P PA + ++ Y GSLTTPP SE V W+V ++PI S Q+ K L + Sbjct: 159 HPAKFFPADKKFYKYSGSLTTPPCSEGVYWMVFKQPIQASVTQLEKMHEYLGS------- 211 Query: 242 HMVNNFRPPQPLKGRVVKASFR 263 N RP Q R + S+ Sbjct: 212 ----NARPVQRQNARTLLKSWP 229 >5HPJ-A nrPDB Length = 217 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 87/257 (33%), Positives = 117/257 (45%), Gaps = 42/257 (16%) Query: 6 GWGYGQDDGPSHWHKLYP-IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNN 64 W Y + G HW + A+G Q+PI+I + L PL L YE ++ + NN Sbjct: 1 EWSYTGEHGTEHWGDSFATCAEGVNQTPIDINQTTQ---AELAPLHLDYEGQVT-ELVNN 56 Query: 65 GHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVH 124 GH++Q + + TV + LKQFHFH SE+ + GK +P E H VH Sbjct: 57 GHTIQANLTGKNTLTV-----DGKTFELKQFHFH------TPSENYLKGKQYPLEAHFVH 105 Query: 125 WNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC-FNP 183 K LAVV V + G S N LT L + KG + NP Sbjct: 106 ATDK------------GELAVVAVMFDFGPR--SNNELTTLLASIPSKGQTVELKEALNP 151 Query: 184 KCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHM 243 LLP R Y+ + GSLTTPP SE V W V++EP S+ Q K +++ M Sbjct: 152 ADLLPRDREYYRFNGSLTTPPCSEGVRWFVMQEPQTSSKAQTEKLQAV-----------M 200 Query: 244 VNNFRPPQPLKGRVVKA 260 NN RP QPL R++ Sbjct: 201 GNNARPLQPLNARLILE 217 >4ETQ-X nrPDB Length = 269 Score = 239 bits (610), Expect = 9e-64, Method: Composition-based stats. Identities = 81/228 (35%), Positives = 121/228 (53%), Gaps = 9/228 (3%) Query: 31 SPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPY 90 SPINI + +A+ + L+PL++ Y +I N G V+++F ++GG L Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLPNEY 61 Query: 91 RLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFL 150 L H +WGK+ D GS H +D + E++LVHWN KKYS++ EA DGL ++ +FL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 151 ETGD-EHPSMNRLTDALYMVRFKGTKAQF-SCFNPKCLLPASRHYWTYPGSLTTPPLSES 208 + D ++ ++ + L +R T A F S F LLP+ Y+TY G TT S Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 209 VTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVN-NFRPPQPLKG 255 WI+ PI I Q+ KFR+LL S + + H + N+R P L Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >4XIW-A nrPDB Length = 239 Score = 237 bits (604), Expect = 4e-63, Method: Composition-based stats. Identities = 81/264 (30%), Positives = 116/264 (43%), Gaps = 40/264 (15%) Query: 6 GWGYGQDDGPSHWHKLYPIAQGDRQSPINI--ISSQAVYSPSLQPLELSYEACMSLSITN 63 W YG+ GP W + A G RQSPINI +S + + +Y + + N Sbjct: 3 AWNYGEVAGPPTWKGV--CATGKRQSPINIPLNTSAPKVDAEMGEFDFAYGSFEKCDVLN 60 Query: 64 NGH-SVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122 GH ++QV+F + + L QFHFH SEH +DG+ + E HL Sbjct: 61 TGHGTMQVNFPAGNLAFIGN-----MELELLQFHFH------APSEHAMDGRRYAMEAHL 109 Query: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGD--EHPSMNRLTDALYMVRFKGTKAQFSC 180 VH N + LAV+G+ LE G ++P+++ + V K Sbjct: 110 VHKN-----------KSTGNLAVLGIMLEPGGLIKNPALSTALEVAPEVPLA-KKPSPKG 157 Query: 181 FNPKCLLPAS-----RHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTS 235 NP LLP R + YPGSLTTPP SE V W V +PI + + Q+ F + + Sbjct: 158 INPVMLLPKKSKAGTRPFVHYPGSLTTPPCSEGVDWFVFMQPIKVPDSQILDFMRFVGDN 217 Query: 236 EDDERIHMVNNFRPPQPLKGRVVK 259 + N RP Q L R+V+ Sbjct: 218 K-----TYATNTRPLQLLNSRLVE 236 >6B9J-X nrPDB Length = 241 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 81/228 (35%), Positives = 121/228 (53%), Gaps = 9/228 (3%) Query: 31 SPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPY 90 SPINI + +A+ + L+PL++ Y +I N G V+++F ++GG L Y Sbjct: 6 SPINIETKKAISNARLKPLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLPNEY 61 Query: 91 RLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFL 150 L H +WGK+ D GS H +D + E++LVHWN KKYS++ EA DGL ++ +FL Sbjct: 62 VLSSLHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGLIIISIFL 121 Query: 151 ETGD-EHPSMNRLTDALYMVRFKGTKAQF-SCFNPKCLLPASRHYWTYPGSLTTPPLSES 208 + D ++ ++ + L +R T A F S F LLP+ Y+TY G TT S Sbjct: 122 QVLDHKNVYFQKIVNQLDSIRSANTSAPFDSVFYLDNLLPSKLDYFTYLG--TTINHSAD 179 Query: 209 VTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVN-NFRPPQPLKG 255 WI+ PI I Q+ KFR+LL S + + H + N+R P L Sbjct: 180 AVWIIFPTPINIHSDQLSKFRTLLSLSNHEGKPHYITENYRNPYKLND 227 >4TWL-A nrPDB Length = 246 Score = 225 bits (573), Expect = 2e-59, Method: Composition-based stats. Identities = 68/255 (26%), Positives = 106/255 (41%), Gaps = 35/255 (13%) Query: 10 GQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNG 65 G +GP +W L P +G QSPI + ++ ++ +L L +Y + + N+G Sbjct: 10 GNPNGPENWGNLKPEWETCGKGMEQSPIQLRDNRVIFDQTLGKLRRNYR-AVDARLRNSG 68 Query: 66 HSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHW 125 H V VDF + + Y+LK+ HFH SEH ++G+ F E LVH Sbjct: 69 HDVLVDFKGNAGSLSIN----RVEYQLKRIHFH------SPSEHEMNGERFDLEAQLVH- 117 Query: 126 NAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGT-KAQFSCFNPK 184 S AVV + G P ++ L D + + +P Sbjct: 118 -----------ESQDQKRAVVSILFRFGRADPFLSDLEDFIKQFSNSQKNEINAGVVDPN 166 Query: 185 CLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMV 244 L Y+ Y GS T PP +E ++W V+R+ +S RQ+ + + + + Sbjct: 167 QLQIDDSAYYRYMGSFTAPPCTEGISWTVMRKVATVSPRQVLLLKQAV-------NENAI 219 Query: 245 NNFRPPQPLKGRVVK 259 NN RP QP R V Sbjct: 220 NNARPLQPTNFRSVF 234 >5TT3-A nrPDB Length = 234 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 66/260 (25%), Positives = 106/260 (40%), Gaps = 45/260 (17%) Query: 7 WGY-GQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSI 61 W Y +++GP W KL+ G QSPINI ++ L+ Y A ++ Sbjct: 10 WDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIE--HYYHTQDKADLQFKYAASKPKAV 67 Query: 62 TNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELH 121 H+++ F ++ Y L HFH E ++ K+ P H Sbjct: 68 FFTHHTLKASFEPTNHINYRGHD-----YVLDNVHFH------APMEFLINNKTRPLSAH 116 Query: 122 LVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCF 181 VH +AK L V+ + E G E+P+++ + + + K F Sbjct: 117 FVHKDAK------------GRLLVLAIGFEEGKENPNLDPILEGIQ------KKQNFKEV 158 Query: 182 NPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERI 241 LP S +Y+ + GSLT PP +E V W V+ EP+ +S +Q+ + + R+ Sbjct: 159 ALDAFLPKSINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKK---------RM 209 Query: 242 HMVNNFRPPQPLKGRVVKAS 261 N RP QP V+ S Sbjct: 210 KNSPNQRPVQPDYNTVIIKS 229 >1Y7W-A nrPDB Length = 291 Score = 201 bits (510), Expect = 3e-52, Method: Composition-based stats. Identities = 74/272 (27%), Positives = 104/272 (38%), Gaps = 44/272 (16%) Query: 18 WHKL-------YPIAQGDRQSPINIISSQ--------AVYSPSLQPLELSYEACMSLSIT 62 W L YP G QSPI+I ++Q + SL L + +++T Sbjct: 32 WPGLQEGGTTKYPACSGSNQSPIDINTNQLMEPSSRSGTSAVSLNGLNVDGAQADGITLT 91 Query: 63 N------NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSF 116 N G V D ++ T+ GG + + QFHFH SEHT++G + Sbjct: 92 NAKVDLEQGMKVTFDQPAANLPTIEIGGTTK-SFVPIQFHFH-----HFLSEHTINGIHY 145 Query: 117 PSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDE-HPSMNRLTDALY------MV 169 P ELH+V A A LAV+G+ + + +N L + Sbjct: 146 PLELHIVMQEQDP------ADVATAQLAVIGIMYKYSENGDAFLNSLQTQIEGKIGDGTA 199 Query: 170 RFKGTKAQFSCFNPKC-LLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKF 228 + T N K LLP+S Y Y GSLTTP E V W V P ++ QM F Sbjct: 200 SYGDTGVSIDNINVKTQLLPSSLKYAGYDGSLTTPGCDERVKWHVFTTPREVTREQMKLF 259 Query: 229 RSLLFTSEDDERIHMVNNFRPPQPLKGRVVKA 260 + + + N R Q L R V Sbjct: 260 VDVTMGAHAGADVV---NNRMIQDLGDREVYK 288 >3Q31-A nrPDB Length = 244 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 67/249 (26%), Positives = 101/249 (40%), Gaps = 34/249 (13%) Query: 8 GYGQDDGPSHWHKL----YPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITN 63 Y GP +W+ L A+G QSPI +I S A+ + L+L + N Sbjct: 12 NYTGLGGPLNWYGLDEANEACAKGKHQSPI-VIDSAAIDYAASGSLKLDLPLADGSKLEN 70 Query: 64 NGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLV 123 G +QV + Y L QFHFH SEH V+ + FP E+H V Sbjct: 71 LGFGLQVTLTNGSLTAN------SKTYTLAQFHFH------TPSEHHVNEEHFPMEVHFV 118 Query: 124 HWNAKKYSTFGEAASAPDGLAVVGVFL---ETGDEHPSMNRLTDALYMVRFKGTKAQFSC 180 A K + AVVG F E GD P + + + + GT Sbjct: 119 FQTAAKET------------AVVGFFFQLSEVGDSVPLFDSVFAPIDNIPDAGTSTTTGQ 166 Query: 181 FNPKCLLP-ASRH-YWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDD 238 + LL +RH + Y GSLTTPP +E V W + EP+ ++ + K + ++ + Sbjct: 167 LDFGGLLDHFNRHGVYQYTGSLTTPPCTEEVMWNLSTEPLPLTVQGYNKVKKIIKYNARY 226 Query: 239 ERIHMVNNF 247 + + + Sbjct: 227 TQNALGQDN 235 >3B1B-A nrPDB Length = 377 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 72/284 (25%), Positives = 109/284 (38%), Gaps = 58/284 (20%) Query: 4 HHGWGYGQDDGPSHW------HKLYPIAQGDRQSPINIISSQA------VYSPSLQPLEL 51 W +G +W + G +QSPIN+ Q + LQ + Sbjct: 37 GDHWD-HGLNG-ENWEGKDGAGNAWVCKTGRKQSPINVPQYQVLDGKGSKIANGLQ-TQW 93 Query: 52 SYEACMS----LSITNNGHSVQVDF------------NDSDDRTVVTGGPLE-------- 87 SY MS + + NNGH++QV + ++T LE Sbjct: 94 SYPDLMSNGTSVQVINNGHTIQVQWTYNYAGHATIAIPAMHNQTNRIVDVLEMRPNDAAD 153 Query: 88 -GPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVV 146 QFHFH SEH + GK +P ELH+VH +K A +V Sbjct: 154 RVTAVPTQFHFH------STSEHLLAGKIYPLELHIVHQVTEKLE-----ACKGGCFSVT 202 Query: 147 GVFLET--GDEHPSMNRLTDALYMVRFKGTKAQFSC---FNPKCLLPASRHYWTYPGSLT 201 G+ + G ++ + + + +GT + LLP+ R Y TY GSLT Sbjct: 203 GILFQLDNGPDNELLEPIFANMPS--REGTFSNLPAGTTIKLGELLPSDRDYVTYEGSLT 260 Query: 202 TPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVN 245 TPP SE + W V+ +P IS Q ++R + E + + Sbjct: 261 TPPCSEGLLWHVMTQPQRISFGQWNRYRLAVGLKECNSTETAAD 304 >5KST-A nrPDB Length = 270 Score = 30.4 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 15/46 (32%) Query: 61 ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVG 106 + N GH V V D D L+ P R KQ H Sbjct: 23 LRNAGHEVMVVAPDRDRSGASNSLTLDTPIRAKQIDMHTYSVAGTP 68 >1S7T-A nrPDB Length = 348 Score = 30.4 bits (67), Expect = 0.87, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 24/60 (40%), Gaps = 15/60 (25%) Query: 11 QDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQV 70 + +GP +W + A+G+ QS + L+ L Y S H++QV Sbjct: 53 EQEGPEYWERETQKAKGNEQS----------FRVDLRTLLGYYNQSKGGS-----HTIQV 97 >5TTH-B nrPDB Length = 672 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 21/50 (42%), Gaps = 4/50 (8%) Query: 210 TWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVK 259 W + EP ISE Q +F + + D R + +R PL R + Sbjct: 247 LW--MMEPKDISEWQHEEFYRYVAQAYDKPRYTLH--YRADAPLNIRSIF 292 >4GF1-A nrPDB Length = 460 Score = 29.3 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 18/45 (40%), Gaps = 1/45 (2%) Query: 112 DGKSFPSELHLVHWNAKKYSTFGE-AASAPDGLAVVGVFLETGDE 155 +GKSFP H V K + A L+ V V+ E G Sbjct: 56 EGKSFPLREHFVFAKGGKEPSLIIHAEDYASHLSSVEVYYELGKA 100 >1PQ3-A nrPDB Length = 306 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 20/48 (41%), Gaps = 9/48 (18%) Query: 27 GDRQSPINIISSQAVYSPSLQPL-------ELSYEACM--SLSITNNG 65 G RQ PI++ + P+L P L+Y M + I N G Sbjct: 217 GKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTG 264 >4OKD-A nrPDB Length = 840 Score = 27.7 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 18/54 (33%), Gaps = 2/54 (3%) Query: 159 MNRLTDALYMVRFKGTKAQFSCFN--PKCLLPASRHYWTYPGSLTTPPLSESVT 210 ++ + + +G F + +L Y+ Y G T ++ V Sbjct: 341 LDVVFNHTAEGNERGPTISFRGLDNRVYYMLAPGGEYYNYSGCGNTLNCNQPVV 394 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.134 0.435 Lambda K H 0.267 0.0416 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,741,629 Number of Sequences: 36641 Number of extensions: 458384 Number of successful extensions: 1296 Number of sequences better than 10.0: 38 Number of HSP's better than 10.0 without gapping: 64 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 992 Number of HSP's gapped (non-prelim): 83 length of query: 264 length of database: 10,336,785 effective HSP length: 95 effective length of query: 169 effective length of database: 6,855,890 effective search space: 1158645410 effective search space used: 1158645410 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (26.9 bits)