BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P43155 (626 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1S5O-A nrPDB 1245 0.0 1T7N-A nrPDB 1160 0.0 2FY4-A nrPDB 521 e-148 1T1U-A nrPDB 498 e-141 1XMD-A nrPDB 316 2e-86 2FYO-A nrPDB 275 4e-74 3O75-A nrPDB 32 0.66 6HIV-A2 nrPDB 31 1.5 5LN3-Z nrPDB 30 2.8 5T0J-f nrPDB 30 3.1 5XL8-A nrPDB 30 4.5 4ZLK-A nrPDB 29 4.7 3QR1-A nrPDB 29 4.9 >1S5O-A nrPDB Length = 616 Score = 1245 bits (3222), Expect = 0.0, Method: Compositional matrix adjust. Identities = 594/605 (98%), Positives = 596/605 (98%) Query: 22 MKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE 81 M+ S H D LPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE Sbjct: 1 MRGSHHHHHHTDPLPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE 60 Query: 82 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 141 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK Sbjct: 61 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 120 Query: 142 LIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPT 201 LIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPT Sbjct: 121 LIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPT 180 Query: 202 HITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAK 261 HITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAK Sbjct: 181 HITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAK 240 Query: 262 AYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNR 321 AYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNR Sbjct: 241 AYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNR 300 Query: 322 WFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKL 381 WFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSP+VPLPMPKKL Sbjct: 301 WFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPMVPLPMPKKL 360 Query: 382 RFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAY 441 RFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAY Sbjct: 361 RFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAY 420 Query: 442 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQ 501 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQ Sbjct: 421 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQ 480 Query: 502 AHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTD 561 AHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVS PDIFMDTSYAIAMHFHLSTSQVPAKTD Sbjct: 481 AHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDTSYAIAMHFHLSTSQVPAKTD 540 Query: 562 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH 621 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH Sbjct: 541 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH 600 Query: 622 PRAKL 626 PRAKL Sbjct: 601 PRAKL 605 >1T7N-A nrPDB Length = 618 Score = 1160 bits (3002), Expect = 0.0, Method: Compositional matrix adjust. Identities = 543/597 (90%), Positives = 576/597 (96%) Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89 AHQDALPRLPVPPLQQSLD+YLKALQPIVSEEEWAHTKQLVDEFQ SGGVGERLQKGLER Sbjct: 22 AHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGERLQKGLER 81 Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149 RA+K ENWLSEWWLKTAYLQ+RQPVVIYSSPGV+LPKQDFVDLQGQLRFAAKLIEGVLDF Sbjct: 82 RAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKLIEGVLDF 141 Query: 150 KVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNY 209 K MIDNETLPVE+LGG+PLCMNQYYQILSSCRVPGPKQD+V NF K+K+PPTHITVVHNY Sbjct: 142 KSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTHITVVHNY 201 Query: 210 QFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKD 269 QFFELDVYHSDGTPLT+DQIFVQLEKIWNSSLQ+NKEPVGILTSNHRN+WAKAYN LIKD Sbjct: 202 QFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKAYNNLIKD 261 Query: 270 KVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQF 329 KVNR+SV SIQKSIFTVCLD +PRVS+DVYR+HVAGQMLHGGGS+ NSGNRWFDKTLQF Sbjct: 262 KVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRWFDKTLQF 321 Query: 330 IVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEI 389 IVAEDGSCG+VYEHAAAEGPPIV L+D+V+EYTKKPELVRSP+VPLPMPKKLRFNITPEI Sbjct: 322 IVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLRFNITPEI 381 Query: 390 KSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQAC 449 K+DIEKAKQNLSIMIQDLDI ++ FHHFGKDFPKSEKLSPDAFIQ+ALQLAYYRIYGQAC Sbjct: 382 KNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYYRIYGQAC 441 Query: 450 ATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDR 509 ATYESASLRMFHLGRTDTIRSAS+DSL FVK M DS+V E QKVELLRKAVQAHR YTDR Sbjct: 442 ATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQAHRAYTDR 501 Query: 510 AIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPV 569 AIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHF+LSTSQVPAKTDCV FFGPV Sbjct: 502 AIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDCVGFFGPV 561 Query: 570 VPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHPRAKL 626 VPDGYG+CYNPMEAHINFS+SAYNSCAETNAAR+AHYLEKALLDMR LLQ+HPRAKL Sbjct: 562 VPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHPRAKL 618 >2FY4-A nrPDB Length = 612 Score = 521 bits (1341), Expect = e-148, Method: Compositional matrix adjust. Identities = 264/602 (43%), Positives = 387/602 (64%), Gaps = 13/602 (2%) Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89 + + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67 Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149 R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL + Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127 Query: 150 KVMIDNETLPVEY----LGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204 K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+ Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187 Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKI--WNSSLQTNKEPVGILTSNHRNSWAKA 262 V QFF LDV + L+ +F QL KI S+ P+G+LTS+ R+ WA+A Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNAAARLPPIGLLTSDGRSEWAEA 246 Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322 L+KD NRDS+ I++ I VCLDA ++ +H A Q+LHGGG N NRW Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPG---GVELSDTHRALQLLHGGGYSKNGANRW 303 Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLR 382 +DK+LQF+V DG+CG+V EH+ +G +V ++++++ +PELVRSP+VPLP P++LR Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQPELVRSPMVPLPAPRRLR 363 Query: 383 FNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYY 442 + +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQLA+Y Sbjct: 364 WKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFY 423 Query: 443 RIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLRKAV 500 R++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D ++V +K+ LL+ A+ Sbjct: 424 RLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAI 483 Query: 501 QAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKT 560 +A YT AI G A D HLL L+ A ++P++FMD +Y ++ F LSTSQVP T Sbjct: 484 RAQTAYTVMAITGMAIDNHLLALRELARAMCAALPEMFMDETYLMSNRFVLSTSQVPTTT 543 Query: 561 DCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS 620 + +GPVVP+GYG CYNP I F +S+++SCA T++++ A +E++L+DMR L Sbjct: 544 EMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCAATSSSKFAKAVEESLIDMRDLCSL 603 Query: 621 HP 622 P Sbjct: 604 LP 605 >1T1U-A nrPDB Length = 639 Score = 498 bits (1283), Expect = e-141, Method: Compositional matrix adjust. Identities = 263/599 (43%), Positives = 377/599 (62%), Gaps = 16/599 (2%) Query: 35 LPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKT 94 LP+LPVPPLQQ+L YL+ +Q +V EE++ ++ +V F A GG+GE LQ+ L R KT Sbjct: 22 LPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKT 81 Query: 95 ENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMID 154 NW+SE+WL YL R + + SSP V+ +Q F D QLRFAA LI GVL +K ++D Sbjct: 82 ANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLD 141 Query: 155 NETLPVEY----LGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHITVVHNY 209 + +LP ++ L G+PLCM QYY++ SS R+PG QDT V+ S P H+ V Sbjct: 142 SHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCN 201 Query: 210 QFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKE--PVGILTSNHRNSWAKAYNTLI 267 QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WAKA L+ Sbjct: 202 QFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLL 260 Query: 268 KDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTL 327 KD NRDS+ I++ I VCLD P E + +H A Q+LHGGG LN NRW+DK+L Sbjct: 261 KDSTNRDSLDMIERCICLVCLDG--PGTGE-LSDTHRALQLLHGGGCSLNGANRWYDKSL 317 Query: 328 QFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEY--TKKPELVRSPLVP-LPMPKKLRFN 384 QF+V DG+CG+V EH+ +G +V ++++++ T +LVR+ V LP P++LR+ Sbjct: 318 QFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRWK 377 Query: 385 ITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRI 444 +PE + + + + L ++++LD V F ++GK F K +K SPD FIQ+ALQLAYYR+ Sbjct: 378 CSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRL 437 Query: 445 YGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDD--SSVTEHQKVELLRKAVQA 502 Y + TYESAS+R F GR D IRSA+ ++L FV+AM D +++ +K++LL+ A+QA Sbjct: 438 YQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQA 497 Query: 503 HRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDC 562 YT AI G A D HLL L+ A + P++FMD +Y ++ F LSTSQVP + Sbjct: 498 QTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEM 557 Query: 563 VMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH 621 +GPVVP+GYG CYNP I F +S+++SC ET++ A + +L+DMR L S Sbjct: 558 FCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSR 616 >1XMD-A nrPDB Length = 612 Score = 316 bits (809), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 208/612 (33%), Positives = 320/612 (52%), Gaps = 40/612 (6%) Query: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERR 90 +QD+LP LPVP L++SL YL++++P +E+E+ T+++V +FQ G G+RL + L R Sbjct: 16 YQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLER 73 Query: 91 ARKTENWLSEWWLKTAYLQYRQPV---VIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVL 147 AR NWL EWWL AYL R P V + P QL + ++ L Sbjct: 74 ARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNL 133 Query: 148 DFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKP---PTHIT 204 ++ ++ E LPV G PL MNQ+ + S+C+VPG +D++ N+ KT+ PTHI Sbjct: 134 NYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIA 193 Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVG----ILTSNHRNSWA 260 V+ + F DV H +G +T ++ QL I + + EPVG LTS R WA Sbjct: 194 VLCRGRAFVFDVLH-EGCLITPPELLRQLTYIHK---KCSNEPVGPSIAALTSEERTRWA 249 Query: 261 KAYNTLIK-DKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSG 319 KA LI D N + IQ S+F ++ + P + + Y +ML GG + Sbjct: 250 KAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQ--VFEMLLGGDPSV--- 304 Query: 320 NRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYT-------KKPELVRSPL 372 RW DK+ I +G G +HA + +V + YV E K E VR Sbjct: 305 -RWGDKSYNLISFANGIFGCCCDHAPYDAMVVVNIAHYVDERVLETEGRWKGSEKVRD-- 361 Query: 373 VPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAF 432 +P+P++L F + +I +D+ +AK DL I F FGK K E L PD F Sbjct: 362 --IPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTF 419 Query: 433 IQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQK 492 IQ+ALQLAYYR++G+ YE+A R F+ GRT+T+RS +++++ + ++M D S + ++ Sbjct: 420 IQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLER 479 Query: 493 VELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHF 549 + + +A H G+ FDRHLLGL L A E+ + +P++F D ++ + +F Sbjct: 480 QQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNF 539 Query: 550 HLSTSQVP-AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLE 608 LSTS V + V+ P+V +GYG Y+ + + S++ SC ET+A +L + Sbjct: 540 VLSTSLVGYLRVQGVVV--PMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIF 597 Query: 609 KALLDMRALLQS 620 A DM L+ + Sbjct: 598 HAFHDMIQLMNT 609 >2FYO-A nrPDB Length = 653 Score = 275 bits (703), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 195/631 (30%), Positives = 317/631 (50%), Gaps = 75/631 (11%) Query: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGL--E 88 +QD+LPRLP+P L+ ++ YL A +P++ + ++ T+ L F+ GVG+ L L + Sbjct: 40 YQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLAQ 97 Query: 89 RRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVML---PKQDFVD--------LQGQLR 137 + K +++S W YL R +V+ +P + PK ++ D +R Sbjct: 98 DKQNKHTSYISGPWFDM-YLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVR 156 Query: 138 FAAKLIEGVLD---------------FKVMIDNETLPVEYLGGK-----PLCMNQYYQIL 177 F L G+L+ FK +I + + G PL M+QY+++ Sbjct: 157 FLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLF 216 Query: 178 SSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIW 237 +S R+P P +D + F+ TK H+ V+ F+ DV DG + +I L+ I Sbjct: 217 NSTRIPRPNRDEL--FTDTKA--RHLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKYIL 272 Query: 238 NSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSE 297 + S + PV LTS +R+ WA+ LI D N ++++ + ++F +CLD P + + Sbjct: 273 SDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLD-DFP-MKD 329 Query: 298 DVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDY 357 ++ SH MLHG G+ NRWFDK+ IVAEDG+ + +EH+ +G ++ + Sbjct: 330 LIHLSHT---MLHGDGT-----NRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNE 381 Query: 358 VI-EYTKKPELVRSPLVPLPMP---------KKLRFNITPEIKSDIEKAKQNLSIMIQDL 407 V + T+ P + P P + L FN++ +K+ I AK+ ++ L Sbjct: 382 VFRDSTQTPAIT-----PQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTL 436 Query: 408 DITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTDT 467 I + F GK+F K ++LSPDA Q+A Q+A+ R YGQ ATYES S F GRT+T Sbjct: 437 SIDSIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTET 496 Query: 468 IRSASM----DSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGL 523 IR AS+ S FV+ SV E Q ++ + + H T A G+ FDRHL L Sbjct: 497 IRPASIFTKRCSEAFVRDPSKHSVGELQ--HMMAECSKYHGQLTKEAAMGQGFDRHLYAL 554 Query: 524 KLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPMEA 583 + A +++P++++D +Y H LSTS + + + F PVVPDG+G+ Y + Sbjct: 555 RYLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDD 614 Query: 584 HINFSLSAYNSCAETNAARLAHYLEKALLDM 614 I ++S+Y+ NA H ++K L D+ Sbjct: 615 WIGCNVSSYSG---RNAREFLHCVQKCLEDI 642 >3O75-A nrPDB Length = 272 Score = 32.3 bits (72), Expect = 0.66, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 44/81 (54%), Gaps = 5/81 (6%) Query: 467 TIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKL- 525 ++ S++ S+ + A + SV++ + +A+Q + G R +GEAF R G +L Sbjct: 114 SLLSSAPRSIALIGARPELSVSQA-RAGGFDEALQGYTGEV-RRYQGEAFSREC-GQRLM 170 Query: 526 -QAIEDLVSMPDIFMDTSYAI 545 Q I+DL +PD + TSY + Sbjct: 171 QQLIDDLGGLPDALVTTSYVL 191 >6HIV-A2 nrPDB Length = 471 Score = 31.2 bits (69), Expect = 1.5, Method: Compositional matrix adjust. Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 7/76 (9%) Query: 15 FLKPFSLMKA-SSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEF 73 LK +++K+ + HQ+ L +P P + +D ++ ++ +V E + T + V+ F Sbjct: 54 LLKERNMLKSMKEHYLRHQEELGAMPAPSRLKMIDESMRNIKRVVKERDEEATARAVEIF 113 Query: 74 QASGGVGERLQKGLER 89 + ERL++G+ R Sbjct: 114 K------ERLKRGIYR 123 >5LN3-Z nrPDB Length = 908 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 11/31 (35%), Positives = 20/31 (64%) Query: 288 LDATMPRVSEDVYRSHVAGQMLHGGGSRLNS 318 LD P+V +D+Y++H+ G GS+++S Sbjct: 337 LDIMEPKVPDDIYKTHLENNRFGGSGSQVDS 367 >5T0J-f nrPDB Length = 749 Score = 30.0 bits (66), Expect = 3.1, Method: Compositional matrix adjust. Identities = 11/31 (35%), Positives = 20/31 (64%) Query: 288 LDATMPRVSEDVYRSHVAGQMLHGGGSRLNS 318 LD P+V +D+Y++H+ G GS+++S Sbjct: 178 LDIMEPKVPDDIYKTHLENNRFGGSGSQVDS 208 >5XL8-A nrPDB Length = 503 Score = 29.6 bits (65), Expect = 4.5, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 19/41 (46%) Query: 343 HAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRF 383 HA A G + TL D +E ELV S +P P LR Sbjct: 14 HAVANGTMVKTLADDQVEVVTAQELVESQNLPELCPSPLRL 54 >4ZLK-A nrPDB Length = 839 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 12/51 (23%), Positives = 22/51 (43%) Query: 442 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQK 492 Y I+ Q CA+ + +M LG D+ ++ +DD+ H + Sbjct: 307 YHIFYQLCASAKLPEFKMLRLGNADSFHYTKQGGSPMIEGVDDAKEMAHTR 357 >3QR1-A nrPDB Length = 813 Score = 29.3 bits (64), Expect = 4.9, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 11/97 (11%) Query: 191 SNFSKTKKP--PTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPV 248 +NF + P +T+ H Y + +LD H L A+ V + W + + + Sbjct: 92 TNFGSSNIPLQDKCVTICHGYNYIDLDWIH-----LVAENSSVAAK--WAEEVFSYAYNL 144 Query: 249 GILTSNHRNSWAKAYN--TLIKDKVNRDSVRSIQKSI 283 L N W K Y T ++ + N+ V+SIQK + Sbjct: 145 LSLNKNQLGEWEKLYFRLTTVEMEKNKIPVKSIQKCL 181 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1S5O-A nrPDB 1008 0.0 1T7N-A nrPDB 989 0.0 2FY4-A nrPDB 885 0.0 1T1U-A nrPDB 864 0.0 1XMD-A nrPDB 774 0.0 2FYO-A nrPDB 708 0.0 Sequences not found previously or not previously below threshold: 4GL2-A nrPDB 34 0.18 5JCF-A nrPDB 31 1.2 5HAX-A nrPDB 31 1.3 4DJE-A nrPDB 30 2.8 3J9M-AO nrPDB 30 3.6 CONVERGED! >1S5O-A nrPDB Length = 616 Score = 1008 bits (2606), Expect = 0.0, Method: Composition-based stats. Identities = 594/605 (98%), Positives = 596/605 (98%) Query: 22 MKASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE 81 M+ S H D LPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE Sbjct: 1 MRGSHHHHHHTDPLPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGE 60 Query: 82 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 141 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK Sbjct: 61 RLQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAK 120 Query: 142 LIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPT 201 LIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPT Sbjct: 121 LIEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPT 180 Query: 202 HITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAK 261 HITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAK Sbjct: 181 HITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAK 240 Query: 262 AYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNR 321 AYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNR Sbjct: 241 AYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNR 300 Query: 322 WFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKL 381 WFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSP+VPLPMPKKL Sbjct: 301 WFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPMVPLPMPKKL 360 Query: 382 RFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAY 441 RFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAY Sbjct: 361 RFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAY 420 Query: 442 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQ 501 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQ Sbjct: 421 YRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQ 480 Query: 502 AHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTD 561 AHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVS PDIFMDTSYAIAMHFHLSTSQVPAKTD Sbjct: 481 AHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSTPDIFMDTSYAIAMHFHLSTSQVPAKTD 540 Query: 562 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH 621 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH Sbjct: 541 CVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSH 600 Query: 622 PRAKL 626 PRAKL Sbjct: 601 PRAKL 605 >1T7N-A nrPDB Length = 618 Score = 989 bits (2558), Expect = 0.0, Method: Composition-based stats. Identities = 544/604 (90%), Positives = 578/604 (95%), Gaps = 2/604 (0%) Query: 23 KASSRFKAHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGER 82 + S AHQDALPRLPVPPLQQSLD+YLKALQPIVSEEEWAHTKQLVDEFQ SGGVGER Sbjct: 17 RGSHM--AHQDALPRLPVPPLQQSLDYYLKALQPIVSEEEWAHTKQLVDEFQTSGGVGER 74 Query: 83 LQKGLERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKL 142 LQKGLERRA+K ENWLSEWWLKTAYLQ+RQPVVIYSSPGV+LPKQDFVDLQGQLRFAAKL Sbjct: 75 LQKGLERRAKKMENWLSEWWLKTAYLQFRQPVVIYSSPGVILPKQDFVDLQGQLRFAAKL 134 Query: 143 IEGVLDFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTH 202 IEGVLDFK MIDNETLPVE+LGG+PLCMNQYYQILSSCRVPGPKQD+V NF K+K+PPTH Sbjct: 135 IEGVLDFKSMIDNETLPVEFLGGQPLCMNQYYQILSSCRVPGPKQDSVVNFLKSKRPPTH 194 Query: 203 ITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVGILTSNHRNSWAKA 262 ITVVHNYQFFELDVYHSDGTPLT+DQIFVQLEKIWNSSLQ+NKEPVGILTSNHRN+WAKA Sbjct: 195 ITVVHNYQFFELDVYHSDGTPLTSDQIFVQLEKIWNSSLQSNKEPVGILTSNHRNTWAKA 254 Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322 YN LIKDKVNR+SV SIQKSIFTVCLD +PRVS+DVYR+HVAGQMLHGGGS+ NSGNRW Sbjct: 255 YNNLIKDKVNRESVNSIQKSIFTVCLDKQVPRVSDDVYRNHVAGQMLHGGGSKFNSGNRW 314 Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLR 382 FDKTLQFIVAEDGSCG+VYEHAAAEGPPIV L+D+V+EYTKKPELVRSP+VPLPMPKKLR Sbjct: 315 FDKTLQFIVAEDGSCGMVYEHAAAEGPPIVALVDHVMEYTKKPELVRSPMVPLPMPKKLR 374 Query: 383 FNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYY 442 FNITPEIK+DIEKAKQNLSIMIQDLDI ++ FHHFGKDFPKSEKLSPDAFIQ+ALQLAYY Sbjct: 375 FNITPEIKNDIEKAKQNLSIMIQDLDIMMLTFHHFGKDFPKSEKLSPDAFIQVALQLAYY 434 Query: 443 RIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQKVELLRKAVQA 502 RIYGQACATYESASLRMFHLGRTDTIRSAS+DSL FVK M DS+V E QKVELLRKAVQA Sbjct: 435 RIYGQACATYESASLRMFHLGRTDTIRSASIDSLAFVKGMGDSTVPEQQKVELLRKAVQA 494 Query: 503 HRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDC 562 HR YTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHF+LSTSQVPAKTDC Sbjct: 495 HRAYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFNLSTSQVPAKTDC 554 Query: 563 VMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHP 622 V FFGPVVPDGYG+CYNPMEAHINFS+SAYNSCAETNAAR+AHYLEKALLDMR LLQ+HP Sbjct: 555 VGFFGPVVPDGYGICYNPMEAHINFSVSAYNSCAETNAARMAHYLEKALLDMRTLLQNHP 614 Query: 623 RAKL 626 RAKL Sbjct: 615 RAKL 618 >2FY4-A nrPDB Length = 612 Score = 885 bits (2288), Expect = 0.0, Method: Composition-based stats. Identities = 263/602 (43%), Positives = 385/602 (63%), Gaps = 13/602 (2%) Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLER 89 + + LP+LPVPPLQQ+L YL+ ++ +VSEE++ ++ +V +F A GG+GE LQ+ L Sbjct: 8 SEESGLPKLPVPPLQQTLATYLQCMRHLVSEEQFRKSQAIVQQFGAPGGLGETLQQKLLE 67 Query: 90 RARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDF 149 R KT NW+SE+WL YL R + + SSP V+ +Q F QLRFAA LI GVL + Sbjct: 68 RQEKTANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFPGTDDQLRFAASLISGVLSY 127 Query: 150 KVMIDNETLPVEY----LGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHIT 204 K ++D+ ++P + L G+PLCM QYY + SS R+PG QDT V+ S P H+ Sbjct: 128 KALLDSHSIPTDCAKGQLSGQPLCMKQYYGLFSSYRLPGHTQDTLVAQNSSIMPEPEHVI 187 Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQT--NKEPVGILTSNHRNSWAKA 262 V QFF LDV + L+ +F QL KI + P+G+LTS+ R+ WA+A Sbjct: 188 VACCNQFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNAAARLPPIGLLTSDGRSEWAEA 246 Query: 263 YNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRW 322 L+KD NRDS+ I++ I VCLDA ++ +H A Q+LHGGG N NRW Sbjct: 247 RTVLVKDSTNRDSLDMIERCICLVCLDAPG---GVELSDTHRALQLLHGGGYSKNGANRW 303 Query: 323 FDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLR 382 +DK+LQF+V DG+CG+V EH+ +G +V ++++++ +PELVRSP+VPLP P++LR Sbjct: 304 YDKSLQFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMTQPELVRSPMVPLPAPRRLR 363 Query: 383 FNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYY 442 + +PEI+ + + + L ++++LD V F ++GK F K +K SPDAFIQ+ALQLA+Y Sbjct: 364 WKCSPEIQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKCSPDAFIQVALQLAFY 423 Query: 443 RIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDS--SVTEHQKVELLRKAV 500 R++ + TYESAS+R F GR D IRSA+ ++L FV+A+ D +V +K+ LL+ A+ Sbjct: 424 RLHRRLVPTYESASIRRFQEGRVDNIRSATPEALAFVRAVTDHKAAVPASEKLLLLKDAI 483 Query: 501 QAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKT 560 +A YT AI G A D HLL L+ A ++P++FMD +Y ++ F LSTSQVP T Sbjct: 484 RAQTAYTVMAITGMAIDNHLLALRELARAMCAALPEMFMDETYLMSNRFVLSTSQVPTTT 543 Query: 561 DCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQS 620 + +GPVVP+GYG CYNP I F +S+++SCA T++++ A +E++L+DMR L Sbjct: 544 EMFCCYGPVVPNGYGACYNPQPETILFCISSFHSCAATSSSKFAKAVEESLIDMRDLCSL 603 Query: 621 HP 622 P Sbjct: 604 LP 605 >1T1U-A nrPDB Length = 639 Score = 864 bits (2233), Expect = 0.0, Method: Composition-based stats. Identities = 262/602 (43%), Positives = 376/602 (62%), Gaps = 16/602 (2%) Query: 35 LPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERRARKT 94 LP+LPVPPLQQ+L YL+ +Q +V EE++ ++ +V F A GG+GE LQ+ L R KT Sbjct: 22 LPKLPVPPLQQTLATYLQCMQHLVPEEQFRKSQAIVKRFGAPGGLGETLQEKLLERQEKT 81 Query: 95 ENWLSEWWLKTAYLQYRQPVVIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVLDFKVMID 154 NW+SE+WL YL R + + SSP V+ +Q F D QLRFAA LI GVL +K ++D Sbjct: 82 ANWVSEYWLNDMYLNNRLALPVNSSPAVIFARQHFQDTNDQLRFAACLISGVLSYKTLLD 141 Query: 155 NETLPVEY----LGGKPLCMNQYYQILSSCRVPGPKQDT-VSNFSKTKKPPTHITVVHNY 209 + +LP ++ L G+PLCM QYY++ SS R+PG QDT V+ S P H+ V Sbjct: 142 SHSLPTDWAKGQLSGQPLCMKQYYRLFSSYRLPGHTQDTLVAQKSSIMPEPEHVIVACCN 201 Query: 210 QFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNK--EPVGILTSNHRNSWAKAYNTLI 267 QFF LDV + L+ +F QL KI + ++ P+G+LTS+ R+ WAKA L+ Sbjct: 202 QFFVLDVV-INFRRLSEGDLFTQLRKIVKMASNEDERLPPIGLLTSDGRSEWAKARTVLL 260 Query: 268 KDKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSGNRWFDKTL 327 KD NRDS+ I++ I VCLD ++ +H A Q+LHGGG LN NRW+DK+L Sbjct: 261 KDSTNRDSLDMIERCICLVCLDGPGTG---ELSDTHRALQLLHGGGCSLNGANRWYDKSL 317 Query: 328 QFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEY--TKKPELVRSPLVP-LPMPKKLRFN 384 QF+V DG+CG+V EH+ +G +V ++++++ T +LVR+ V LP P++LR+ Sbjct: 318 QFVVGRDGTCGVVCEHSPFDGIVLVQCTEHLLKHMMTSNKKLVRADSVSELPAPRRLRWK 377 Query: 385 ITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRI 444 +PE + + + + L ++++LD V F ++GK F K +K SPD FIQ+ALQLAYYR+ Sbjct: 378 CSPETQGHLASSAEKLQRIVKNLDFIVYKFDNYGKTFIKKQKYSPDGFIQVALQLAYYRL 437 Query: 445 YGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDS--SVTEHQKVELLRKAVQA 502 Y + TYESAS+R F GR D IRSA+ ++L FV+AM D ++ +K++LL+ A+QA Sbjct: 438 YQRLVPTYESASIRRFQEGRVDNIRSATPEALAFVQAMTDHKAAMPASEKLQLLQTAMQA 497 Query: 503 HRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDC 562 YT AI G A D HLL L+ A + P++FMD +Y ++ F LSTSQVP + Sbjct: 498 QTEYTVMAITGMAIDNHLLALRELARDLCKEPPEMFMDETYLMSNRFVLSTSQVPTTMEM 557 Query: 563 VMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQSHP 622 +GPVVP+GYG CYNP I F +S+++SC ET++ A + +L+DMR L S Sbjct: 558 FCCYGPVVPNGYGACYNPQPEAITFCISSFHSCKETSSVEFAEAVGASLVDMRDLCSSRQ 617 Query: 623 RA 624 A Sbjct: 618 PA 619 >1XMD-A nrPDB Length = 612 Score = 774 bits (1999), Expect = 0.0, Method: Composition-based stats. Identities = 208/612 (33%), Positives = 320/612 (52%), Gaps = 40/612 (6%) Query: 31 HQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGLERR 90 +QD+LP LPVP L++SL YL++++P +E+E+ T+++V +FQ G G+RL + L R Sbjct: 16 YQDSLPSLPVPALEESLKKYLESVKPFANEDEYKKTEEIVQKFQE--GAGKRLHQKLLER 73 Query: 91 ARKTENWLSEWWLKTAYLQYRQPV---VIYSSPGVMLPKQDFVDLQGQLRFAAKLIEGVL 147 AR NWL EWWL AYL R P V + P QL + ++ L Sbjct: 74 ARGKRNWLEEWWLNVAYLDVRIPSQLNVNFVGPCPHFEHYWPAREGTQLERGSMMLWHNL 133 Query: 148 DFKVMIDNETLPVEYLGGKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKP---PTHIT 204 ++ ++ E LPV G PL MNQ+ + S+C+VPG +D++ N+ KT+ PTHI Sbjct: 134 NYWQLLRREKLPVHKSGNTPLDMNQFRMLFSTCKVPGITRDSIMNYFKTESEGHCPTHIA 193 Query: 205 VVHNYQFFELDVYHSDGTPLTADQIFVQLEKIWNSSLQTNKEPVG----ILTSNHRNSWA 260 V+ + F DV H +G +T ++ QL I + + EPVG LTS R WA Sbjct: 194 VLCRGRAFVFDVLH-EGCLITPPELLRQLTYIHK---KCSNEPVGPSIAALTSEERTRWA 249 Query: 261 KAYNTLIK-DKVNRDSVRSIQKSIFTVCLDATMPRVSEDVYRSHVAGQMLHGGGSRLNSG 319 KA LI D N + IQ S+F ++ + P + + Y +ML GG + Sbjct: 250 KAREYLISLDPENLTLLEKIQTSLFVYSIEDSSPHATPEEYSQ--VFEMLLGGDPSV--- 304 Query: 320 NRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLDYVIEYT-------KKPELVRSPL 372 RW DK+ I +G G +HA + +V + YV E K E VR Sbjct: 305 -RWGDKSYNLISFANGIFGCCCDHAPYDAMVVVNIAHYVDERVLETEGRWKGSEKVRD-- 361 Query: 373 VPLPMPKKLRFNITPEIKSDIEKAKQNLSIMIQDLDITVMVFHHFGKDFPKSEKLSPDAF 432 +P+P++L F + +I +D+ +AK DL I F FGK K E L PD F Sbjct: 362 --IPLPEELVFTVDEKILNDVSQAKAQHLKAASDLQIAASTFTSFGKKLTKEEALHPDTF 419 Query: 433 IQMALQLAYYRIYGQACATYESASLRMFHLGRTDTIRSASMDSLTFVKAMDDSSVTEHQK 492 IQ+ALQLAYYR++G+ YE+A R F+ GRT+T+RS +++++ + ++M D S + ++ Sbjct: 420 IQLALQLAYYRLHGRPGCCYETAMTRYFYHGRTETVRSCTVEAVRWCQSMQDPSASLLER 479 Query: 493 VELLRKAVQAHRGYTDRAIRGEAFDRHLLGLKLQAIEDLVSMPDIFMDTSYAIA---MHF 549 + + +A H G+ FDRHLLGL L A E+ + +P++F D ++ + +F Sbjct: 480 QQKMLEAFAKHNKMMKDCSHGKGFDRHLLGLLLIAKEEGLPVPELFEDPLFSRSGGGGNF 539 Query: 550 HLSTSQVP-AKTDCVMFFGPVVPDGYGVCYNPMEAHINFSLSAYNSCAETNAARLAHYLE 608 LSTS V + V+ P+V +GYG Y+ + + S++ SC ET+A +L + Sbjct: 540 VLSTSLVGYLRVQGVVV--PMVHNGYGFFYHIRDDRFVVACSSWRSCPETDAEKLVQMIF 597 Query: 609 KALLDMRALLQS 620 A DM L+ + Sbjct: 598 HAFHDMIQLMNT 609 >2FYO-A nrPDB Length = 653 Score = 708 bits (1828), Expect = 0.0, Method: Composition-based stats. Identities = 196/637 (30%), Positives = 319/637 (50%), Gaps = 75/637 (11%) Query: 30 AHQDALPRLPVPPLQQSLDHYLKALQPIVSEEEWAHTKQLVDEFQASGGVGERLQKGL-- 87 +QD+LPRLP+P L+ ++ YL A +P++ + ++ T+ L F+ GVG+ L L Sbjct: 39 HYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFET--GVGKELHAHLLA 96 Query: 88 ERRARKTENWLSEWWLKTAYLQYRQPVVIYSSPGVML---PKQDFVD--------LQGQL 136 + + K +++S W YL R +V+ +P + PK ++ D + Sbjct: 97 QDKQNKHTSYISGPWFD-MYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAV 155 Query: 137 RFAAKLIEGVLD---------------FKVMIDNETLPVEYLGGK-----PLCMNQYYQI 176 RF L G+L+ FK +I + + G PL M+QY+++ Sbjct: 156 RFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRL 215 Query: 177 LSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFELDVYHSDGTPLTADQIFVQLEKI 236 +S R+P P +D + F+ TK H+ V+ F+ DV DG + +I L+ I Sbjct: 216 FNSTRIPRPNRDEL--FTDTKA--RHLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKYI 271 Query: 237 WNSSLQTNKEPVGILTSNHRNSWAKAYNTLIKDKVNRDSVRSIQKSIFTVCLDATMPRVS 296 + S + PV LTS +R+ WA+ LI D N ++++ + ++F +CLD P + Sbjct: 272 LSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDG-NEETLKKVDSAVFCLCLD-DFP-MK 328 Query: 297 EDVYRSHVAGQMLHGGGSRLNSGNRWFDKTLQFIVAEDGSCGLVYEHAAAEGPPIVTLLD 356 + ++ SH MLHG G+ NRWFDK+ IVAEDG+ + +EH+ +G ++ + Sbjct: 329 DLIHLSHT---MLHGDGT-----NRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFN 380 Query: 357 YVI-EYTKKPELVRSPLVPLPMP---------KKLRFNITPEIKSDIEKAKQNLSIMIQD 406 V + T+ P + P P + L FN++ +K+ I AK+ ++ Sbjct: 381 EVFRDSTQTPAIT-----PQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKT 435 Query: 407 LDITVMVFHHFGKDFPKSEKLSPDAFIQMALQLAYYRIYGQACATYESASLRMFHLGRTD 466 L I + F GK+F K ++LSPDA Q+A Q+A+ R YGQ ATYES S F GRT+ Sbjct: 436 LSIDSIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTE 495 Query: 467 TIRSASM----DSLTFVKAMDDSSVTEHQKVELLRKAVQAHRGYTDRAIRGEAFDRHLLG 522 TIR AS+ S FV+ SV E Q ++ + + H T A G+ FDRHL Sbjct: 496 TIRPASIFTKRCSEAFVRDPSKHSVGELQ--HMMAECSKYHGQLTKEAAMGQGFDRHLYA 553 Query: 523 LKLQAIEDLVSMPDIFMDTSYAIAMHFHLSTSQVPAKTDCVMFFGPVVPDGYGVCYNPME 582 L+ A +++P++++D +Y H LSTS + + + F PVVPDG+G+ Y + Sbjct: 554 LRYLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHD 613 Query: 583 AHINFSLSAYNSCAETNAARLAHYLEKALLDMRALLQ 619 I ++S+Y+ NA H ++K L D+ L+ Sbjct: 614 DWIGCNVSSYSG---RNAREFLHCVQKCLEDIFDALE 647 >4GL2-A nrPDB Length = 699 Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 36/91 (39%), Gaps = 2/91 (2%) Query: 341 YEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEIKSDIEKAK--Q 398 H E + Y+++ K L + +P+P+ L +P + ++AK + Sbjct: 145 CHHTNKEAVYNNIMRHYLMQKLKNNRLKKENKPVIPLPQILGLTASPGVGGATKQAKAEE 204 Query: 399 NLSIMIQDLDITVMVFHHFGKDFPKSEKLSP 429 ++ + +LD + D K++ P Sbjct: 205 HILKLCANLDAFTIKTVKENLDQLKNQIQEP 235 >5JCF-A nrPDB Length = 701 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 28/70 (40%), Gaps = 2/70 (2%) Query: 341 YEHAAAEGPPIVTLLDYVIEYTKKPELVRSPLVPLPMPKKLRFNITPEIKS--DIEKAKQ 398 H EG + Y+ E K + + +P P+ L +P + KA++ Sbjct: 144 CHHTQKEGVYNNIMRRYLKEKIKNRKQAKENKPLIPQPQILGLTASPGVGGARSNSKAEE 203 Query: 399 NLSIMIQDLD 408 ++ + +LD Sbjct: 204 HILKICANLD 213 >5HAX-A nrPDB Length = 742 Score = 31.2 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 30/85 (35%), Gaps = 4/85 (4%) Query: 158 LPVEYLG---GKPLCMNQYYQILSSCRVPGPKQDTVSNFSKTKKPPTHITVVHNYQFFEL 214 PV + L ++ Y L S PG D S + P H+ HN Sbjct: 4 PPVAKAAQVVNQTLQLDDSYPDLDSYCRPGASSDYEMQSSDSSWAPFHVVRHHNIPDKVF 63 Query: 215 DVYHSDGTPLTADQIFVQLEKIWNS 239 + ++ G T +F ++ W S Sbjct: 64 EHLNA-GEVFTKLGLFAEIGYAWAS 87 >4DJE-A nrPDB Length = 262 Score = 30.1 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 18/76 (23%), Positives = 30/76 (39%), Gaps = 8/76 (10%) Query: 480 KAMDDSSVTEHQKVELLRKAVQAHRG------YTDRAIRGEAFDRHLLGLKLQAIED--L 531 +AM +S+ E +KVE L H I ++ R ++L A D Sbjct: 92 RAMINSTNAEREKVEKLFPLAVEHGAALIGLTMNKTGIPKDSDTRLAFAMELVAAADEFG 151 Query: 532 VSMPDIFMDTSYAIAM 547 + M D+++D A Sbjct: 152 LPMEDLYIDPLILPAN 167 >3J9M-AO nrPDB Length = 258 Score = 29.7 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 14/66 (21%) Query: 1 MLAFAARTVVKPLGFLKPFSLMKASSRFK-----------AHQDALPRLPVPPLQQSLDH 49 M A TV++ L L SL + S R + + +D+L +P+ P + Sbjct: 1 MAASVLNTVLRRLPML---SLFRGSHRVQVPLQTLCTKAPSEEDSLSSVPISPYKDEPWK 57 Query: 50 YLKALQ 55 YL++ + Sbjct: 58 YLESEE 63 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.130 0.344 Lambda K H 0.267 0.0397 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 22,391,222 Number of Sequences: 36641 Number of extensions: 875635 Number of successful extensions: 6501 Number of sequences better than 10.0: 55 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 6377 Number of HSP's gapped (non-prelim): 79 length of query: 626 length of database: 10,336,785 effective HSP length: 103 effective length of query: 523 effective length of database: 6,562,762 effective search space: 3432324526 effective search space used: 3432324526 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 62 (28.5 bits)