BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P42773
(168 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
1G3N-B nrPDB 339 4e-94
1BLX-B nrPDB 135 8e-33
1BD8-A nrPDB 130 3e-31
2A5E-A nrPDB 93 5e-20
5AQ9-A nrPDB 92 9e-20
1D9S-A nrPDB 91 3e-19
5H76-A nrPDB 87 5e-18
5AQB-A nrPDB 87 5e-18
6FES-A nrPDB 78 1e-15
5AQ7-A nrPDB 78 2e-15
2DWZ-A nrPDB 75 1e-14
5AQA-A nrPDB 75 2e-14
4NIK-A nrPDB 74 3e-14
6MWQ-A nrPDB 72 8e-14
5MIO-C nrPDB 72 1e-13
5CBO-A nrPDB 71 2e-13
5GP7-A nrPDB 60 3e-10
5JHQ-A nrPDB 58 2e-09
5ET1-A nrPDB 57 4e-09
3B7B-A nrPDB 57 5e-09
6BY9-A nrPDB 56 7e-09
5HKP-A nrPDB 56 7e-09
4Z68-A nrPDB 54 4e-08
1WG0-A nrPDB 52 1e-07
3EU9-A nrPDB 52 2e-07
3UI2-A nrPDB 49 9e-07
3DEO-A nrPDB 48 2e-06
3EHQ-A nrPDB 47 3e-06
4O1O-A nrPDB 46 1e-05
6AUN-A nrPDB 45 1e-05
5DND-A nrPDB 43 5e-05
4OAU-C nrPDB 43 5e-05
5U0K-A nrPDB 42 9e-05
4OT9-A nrPDB 42 2e-04
5UQE-A nrPDB 42 2e-04
5U0J-A nrPDB 40 4e-04
6EMK-G nrPDB 40 4e-04
5D68-A nrPDB 39 0.001
3LJN-A nrPDB 35 0.012
2KXP-C nrPDB 35 0.017
3ZKJ-A nrPDB 34 0.032
4BSZ-B nrPDB 33 0.045
6BOA-A nrPDB 32 0.12
6GYM-3 nrPDB 32 0.19
6E2G-A nrPDB 31 0.24
2ISQ-A nrPDB 31 0.24
1DCQ-A nrPDB 31 0.25
4AEC-A nrPDB 31 0.29
3T9K-A nrPDB 31 0.30
2RFA-A nrPDB 31 0.32
4LMA-A nrPDB 30 0.42
3LVQ-E nrPDB 30 0.46
5WP0-A nrPDB 30 0.54
2B0O-E nrPDB 30 0.69
6DMR-A nrPDB 30 0.70
6CUD-A nrPDB 30 0.73
3Q4G-A nrPDB 29 0.81
1W5T-A nrPDB 29 0.81
6CV9-A nrPDB 29 0.88
1XLT-A nrPDB 28 1.5
4QJ1-A nrPDB 28 1.5
6DJS-A nrPDB 28 1.6
3T4P-A nrPDB 28 1.6
3FFS-A nrPDB 28 1.7
2NYJ-A nrPDB 28 1.8
5IRX-A nrPDB 28 1.9
4LMB-A nrPDB 28 2.0
4LG1-A nrPDB 27 3.1
6ED3-A nrPDB 27 4.6
6DVZ-A nrPDB 27 4.8
5XE7-A nrPDB 27 5.2
3AUJ-A nrPDB 26 7.0
4XD0-A nrPDB 26 7.7
2RON-A nrPDB 26 8.1
6BO5-A nrPDB 26 8.3
5HI9-A nrPDB 26 8.3
>1G3N-B nrPDB
Length = 168
Score = 339 bits (869), Expect = 4e-94, Method: Compositional matrix adjust.
Identities = 168/168 (100%), Positives = 168/168 (100%)
Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60
MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG
Sbjct: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE
Sbjct: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168
FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
Sbjct: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168
>1BLX-B nrPDB
Length = 166
Score = 135 bits (340), Expect = 8e-33, Method: Compositional matrix adjust.
Identities = 72/155 (46%), Positives = 106/155 (68%), Gaps = 3/155 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+P +A LL +GA+P+
Sbjct: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPN 68
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
++D +G + +HDAAR GFLDTL+ L+E ADVN D+ G+LP+HLA +EGH VV FL
Sbjct: 69 VQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAP 128
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
S++ HR+ G T +LAR G ++ ++Q +
Sbjct: 129 E--SDLHHRDASGLTPLELARQRGAQNLMDILQGH 161
>1BD8-A nrPDB
Length = 156
Score = 130 bits (327), Expect = 3e-31, Method: Compositional matrix adjust.
Identities = 71/155 (45%), Positives = 104/155 (67%), Gaps = 3/155 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+ IA LL +GA+P+
Sbjct: 3 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 62
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
++D +G + +HDAAR GFLDTL+ L+E ADVN+ D G LP+HLA +EGH VV FL
Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 122
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
S++ R+ +G T +LA G ++V ++Q +
Sbjct: 123 E--SDLHRRDARGLTPLELALQRGAQDLVDILQGH 155
>2A5E-A nrPDB
Length = 156
Score = 93.2 bits (230), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%)
Query: 3 EPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN 62
EP + LA+AAARG +E++ +LL+ NA N +GR +QVM +G+ +A LLL GA
Sbjct: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAE 69
Query: 63 PDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
P+ D +HDAAR GFLDTL L A +++ D G LP+ LA + GH V +
Sbjct: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129
Query: 122 LVKHTASNVGHRNHKGDTA 140
L G + + D A
Sbjct: 130 LRAAAGGTRGSNHARIDAA 148
>5AQ9-A nrPDB
Length = 422
Score = 92.4 bits (228), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 62/157 (39%), Positives = 90/157 (57%), Gaps = 2/157 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D
Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K
Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 134
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
H A +V ++ G T DLA G ++V +L+Q A
Sbjct: 135 HGA-DVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAA 170
>1D9S-A nrPDB
Length = 136
Score = 90.5 bits (223), Expect = 3e-19, Method: Compositional matrix adjust.
Identities = 50/115 (43%), Positives = 70/115 (60%), Gaps = 1/115 (0%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDR 68
LA+AAARG +E + LL+ + NA N FGR +QVM +G+ ++A LLL GA P+ D
Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCADP 75
Query: 69 TGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122
+HDAAR GFLDTL L A +++ D G LP+ LA ++GH + +L
Sbjct: 76 ATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYL 130
>5H76-A nrPDB
Length = 201
Score = 86.7 bits (213), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 57/152 (37%), Positives = 86/152 (56%), Gaps = 3/152 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D
Sbjct: 7 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 66
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K
Sbjct: 67 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 126
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
H A N ++ G TA D++ G ++ ++
Sbjct: 127 HGAVNA--QDKFGKTAFDISIDNGNEDLAQIL 156
Score = 66.2 bits (160), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 40/86 (46%), Positives = 52/86 (60%), Gaps = 1/86 (1%)
Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135
+AARAG D ++ L+ ADVN DN G PLHLAA GHL +VE L+KH A +V +
Sbjct: 12 EAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGA-DVDASDV 70
Query: 136 KGDTACDLARLYGRNEVVSLMQANGA 161
G T LA +G E+V ++ NGA
Sbjct: 71 FGYTPLHLAAYWGHLEIVEVLLKNGA 96
>5AQB-A nrPDB
Length = 428
Score = 86.7 bits (213), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 56/151 (37%), Positives = 85/151 (56%), Gaps = 1/151 (0%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65
G +L AA G ++ L+ N +VNA + G T L + G+ EI LL GA+ +
Sbjct: 15 GKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVNA 74
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
D G+ +H AA +G L+ ++ LL++ ADVN +D G PLHLAA GHL +VE L+K+
Sbjct: 75 ADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKN 134
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
A +V ++ G T DLA G ++ ++
Sbjct: 135 GA-DVNAQDKFGKTPRDLAIDNGNEDIAEVL 164
Score = 74.3 bits (181), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/125 (37%), Positives = 71/125 (56%), Gaps = 2/125 (1%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
G+ L+ + G + R L+ GA+ + D G+ +H AA G L+ ++ LL+ ADV
Sbjct: 14 LGKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADV 72
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
N D +G PLHLAA GHL +VE L+K+ A +V + G T LA ++G E+V ++
Sbjct: 73 NAADIDGYTPLHLAAFSGHLEIVEVLLKYGA-DVNADDQAGFTPLHLAAIFGHLEIVEVL 131
Query: 157 QANGA 161
NGA
Sbjct: 132 LKNGA 136
Score = 62.8 bits (151), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 48/130 (36%), Positives = 66/130 (50%), Gaps = 9/130 (6%)
Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTGF 71
AA G LE + LL+N +VNA + G T L + G+ EI LL GA+ + D+ GF
Sbjct: 54 AAWGHLEIVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGF 113
Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL--------V 123
+H AA G L+ ++ LL+ ADVN +D G P LA G+ + E L V
Sbjct: 114 TPLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKV 173
Query: 124 KHTASNVGHR 133
K A +G R
Sbjct: 174 KDAADQLGAR 183
>6FES-A nrPDB
Length = 367
Score = 78.2 bits (191), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 1/125 (0%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ ADV
Sbjct: 6 LGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 65
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
N D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V ++
Sbjct: 66 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-VNATDVIGTAPLHLAAMWGHEEIVEVL 124
Query: 157 QANGA 161
NGA
Sbjct: 125 LKNGA 129
Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 41/87 (47%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135
+AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V +
Sbjct: 12 EAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNANDE 70
Query: 136 KGDTACDLARLYGRNEVVSLMQANGAG 162
+G T LA G E+V ++ NGAG
Sbjct: 71 RGHTPLHLAAYTGHLEIVEVLLKNGAG 97
Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 47/144 (32%), Positives = 61/144 (42%), Gaps = 33/144 (22%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGF 71
AA G L + LL+N +VNA + G T L
Sbjct: 46 AAWEGHLGIVEVLLKNGADVNANDERGHTPL----------------------------- 76
Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131
H AA G L+ ++ LL+ A VN D G PLHLAA GH +VE L+K+ A +
Sbjct: 77 ---HLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGA-DAR 132
Query: 132 HRNHKGDTACDLARLYGRNEVVSL 155
++ G T DLAR G V L
Sbjct: 133 AQDKFGKTPEDLARDNGYESVARL 156
Score = 25.8 bits (55), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPE----IARRLLLRGANPDLKD 67
AA G E + LL+N + AQ+ FG+T + + E +AR+ ++R +LK+
Sbjct: 112 AAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARLARKEIIRAVVDELKE 171
>5AQ7-A nrPDB
Length = 418
Score = 77.8 bits (190), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 48/125 (38%), Positives = 68/125 (54%), Gaps = 1/125 (0%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ ADV
Sbjct: 14 LGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 73
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
N D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V ++
Sbjct: 74 NANDERGHTPLHLAAYTGHLEIVEVLLKNGA-GVNATDVIGTAPLHLAAMWGYKEIVEVL 132
Query: 157 QANGA 161
GA
Sbjct: 133 LKAGA 137
Score = 65.9 bits (159), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 41/87 (47%), Positives = 53/87 (60%), Gaps = 1/87 (1%)
Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135
+AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V +
Sbjct: 20 EAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNANDE 78
Query: 136 KGDTACDLARLYGRNEVVSLMQANGAG 162
+G T LA G E+V ++ NGAG
Sbjct: 79 RGHTPLHLAAYTGHLEIVEVLLKNGAG 105
Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 43/113 (38%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70
AA G L + LL+N +VNA + G T L + G+ EI LL GA + D G
Sbjct: 54 AAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIG 113
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
A +H AA G+ + ++ LL+ ADV+ +D G PL LAA +GH + LV
Sbjct: 114 TAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166
>2DWZ-A nrPDB
Length = 231
Score = 75.5 bits (184), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 51/118 (43%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDLKDRTG 70
AA+ G E + +LL +VNA N G T L N EIA LL GANPD KD
Sbjct: 80 AASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYD 139
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128
+H AA G L + LL ++A NI+D EGN PLHLA E + +FLV AS
Sbjct: 140 ATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGAS 197
Score = 34.7 bits (78), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 73 VIHDAARAGFLDTLQT-LLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131
+I + A +G LD L+ +L ++ D + LH A GH +VEFL++ V
Sbjct: 9 MICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ-LGVPVN 67
Query: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161
++ G + +A GR+E+V + GA
Sbjct: 68 DKDDAGWSPLHIAASAGRDEIVKALLVKGA 97
>5AQA-A nrPDB
Length = 418
Score = 74.7 bits (182), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 47/125 (37%), Positives = 69/125 (55%), Gaps = 1/125 (0%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ ADV
Sbjct: 14 LGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 73
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V ++
Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYKEIVEVL 132
Query: 157 QANGA 161
GA
Sbjct: 133 LKAGA 137
Score = 66.6 bits (161), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 42/113 (37%), Positives = 63/113 (55%), Gaps = 1/113 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70
AA G LE + LL++ +V+A + FG T L + G+ EI LL GA+ + D G
Sbjct: 54 AAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDG 113
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
+H AA+ G+ + ++ LL+ ADV+ +D G PL LAA +GH + LV
Sbjct: 114 MTPLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166
>4NIK-A nrPDB
Length = 230
Score = 73.9 bits (180), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 50/118 (42%), Positives = 60/118 (50%), Gaps = 1/118 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDLKDRTG 70
AA+ G E + +LL VNA N G T L N EIA LL GANPD KD
Sbjct: 84 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 143
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128
+H AA G L + LL ++A NI+D EGN PLHLA E + + LV AS
Sbjct: 144 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 201
Score = 33.5 bits (75), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 73 VIHDAARAGFLDTL-QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131
++ + A +G L+ L +++L ++ D + LH A GH +VEFL++ V
Sbjct: 13 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ-LGVPVN 71
Query: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161
++ G + +A GR+E+V + GA
Sbjct: 72 DKDDAGWSPLHIAASAGRDEIVKALLGKGA 101
>6MWQ-A nrPDB
Length = 493
Score = 72.4 bits (176), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 1/125 (0%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
G+ L+ + G + R L+ GA+ + DR G +H AA+ G L+ ++ LL+ ADV
Sbjct: 5 LGKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV 64
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
N D G PLHLAA GHL +VE L+K+ A +V + G T L + G E+V ++
Sbjct: 65 NAADLWGQTPLHLAATAGHLEIVEVLLKYGA-DVNALDLIGKTPLHLTAIDGHLEIVEVL 123
Query: 157 QANGA 161
+GA
Sbjct: 124 LKHGA 128
Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 1/123 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70
AA RG LE + LL+ +VNA + +G+T L + G+ EI LL GA+ + D G
Sbjct: 45 AAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIG 104
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
+H A G L+ ++ LL+ ADVN +D G ++ G+ + E L K S++
Sbjct: 105 KTPLHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDI 164
Query: 131 GHR 133
HR
Sbjct: 165 AHR 167
>5MIO-C nrPDB
Length = 573
Score = 72.0 bits (175), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 46/125 (36%), Positives = 70/125 (56%), Gaps = 1/125 (0%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
G+ L+ + G + R L+ GA+ + D +G +H AA G L+ ++ LL+ ADV
Sbjct: 410 LGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV 469
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+ D G+ PLHLAA GHL +VE L+KH A +V + GDT LA + G ++V +
Sbjct: 470 SASDLMGSTPLHLAALIGHLEIVEVLLKHGA-DVNAVDTWGDTPLRLAAVMGHLKIVEAL 528
Query: 157 QANGA 161
+GA
Sbjct: 529 LKHGA 533
Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 1/114 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70
AA G LE + LL++ +V+A + G T L + L G+ EI LL GA+ + D G
Sbjct: 450 AATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWG 509
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
+ AA G L ++ LL+ ADVN +D G + G + E L K
Sbjct: 510 DTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563
Score = 33.5 bits (75), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 3 EPWGN-ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTA 41
+ WG+ L AA G L+ + +LL++ +VNAQ+ FG+TA
Sbjct: 506 DTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTA 545
>5CBO-A nrPDB
Length = 176
Score = 71.2 bits (173), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 43/125 (34%), Positives = 69/125 (55%), Gaps = 1/125 (0%)
Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96
G+ L+ G + R L+ GA+ + D G +H AA G + ++ LL++ ADV
Sbjct: 3 LGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADV 62
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
N D G+ PLHLAAK G+L +VE L+K+ A +V ++ G TA D++ G ++ ++
Sbjct: 63 NASDATGDTPLHLAAKWGYLGIVEVLLKYGA-DVNAQDKFGKTAFDISIDNGNEDLAEIL 121
Query: 157 QANGA 161
N A
Sbjct: 122 CKNKA 126
Score = 65.5 bits (158), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 42/123 (34%), Positives = 66/123 (53%), Gaps = 1/123 (0%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + FG T L + G+ EI LL GA+ +
Sbjct: 4 GKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVN 63
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D TG +H AA+ G+L ++ LL++ ADVN +D G ++ G+ + E L K
Sbjct: 64 ASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCK 123
Query: 125 HTA 127
+ A
Sbjct: 124 NKA 126
>5GP7-A nrPDB
Length = 169
Score = 60.5 bits (145), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 44/138 (31%), Positives = 67/138 (48%), Gaps = 3/138 (2%)
Query: 9 LASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA +G L ++ L N+N G T L + N E+A LL GA+ + +
Sbjct: 13 LLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 72
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D+ G +H+AA G +D L+++ VN D PLH AA++G ++ L+ H
Sbjct: 73 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHG 132
Query: 127 ASNVGHRNHKGDTACDLA 144
A +N +G T DLA
Sbjct: 133 ADPT-MKNQEGQTPLDLA 149
Score = 43.1 bits (100), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLKDRTG 70
AA +LE LL++ +VNAQ+ G L G+ +IA L+ + D+
Sbjct: 50 AAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWA 109
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKE 113
F +H+AA+ G LL AD +++ EG PL LA +
Sbjct: 110 FTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD 152
>5JHQ-A nrPDB
Length = 482
Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 48/141 (34%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV---MKLGNPEIARRLLLRGANPD 64
EL A GD+ ++ L+ + NVNA++ GR + + G ++ LL GAN
Sbjct: 18 ELLEACRNGDVSRVKRLV-DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVH 76
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
+D G +H+A G + + LL AD N DN PLH AA +G + V L++
Sbjct: 77 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 136
Query: 125 HTA-SNVGHRNHKGDTACDLA 144
H A N+ RN G +A DLA
Sbjct: 137 HGADPNI--RNTDGKSALDLA 155
Score = 56.2 bits (134), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64
+EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+
Sbjct: 170 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 229
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+
Sbjct: 230 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 289
Query: 125 HTASNVGHRNHKGDTACDLA 144
H A H G +A D+A
Sbjct: 290 HGADPTLVNCH-GKSAVDMA 308
Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 4/124 (3%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV----MKLGNPEIARRLLLRGA 61
G+ L AA DL ++ L + Q TAL + ++ LL +GA
Sbjct: 323 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 382
Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
N + K++ +H AA D ++ L + A +N D G LH AA GHL+
Sbjct: 383 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 442
Query: 122 LVKH 125
L+ +
Sbjct: 443 LLSY 446
Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 32/88 (36%), Positives = 47/88 (53%), Gaps = 4/88 (4%)
Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEG--NLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
+A R G + ++ L++ A+VN +D G + PLH AA G VVE L++ +NV R
Sbjct: 21 EACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ-MGANVHAR 78
Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGA 161
+ G A +G EVVSL+ GA
Sbjct: 79 DDGGLIPLHNACSFGHAEVVSLLLCQGA 106
Score = 31.2 bits (69), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 30/180 (16%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRL--------LLRG 60
L AA++ +E + LL + + N G++A+ + PE+ RL LL+
Sbjct: 272 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAP--TPELRERLTYEFKGHSLLQA 329
Query: 61 AN----PDLKDRTGFAVI-------HDAARAGFLDTL--------QTLLEFQADVNIEDN 101
A +K +I H+ A + +L + LL A+VN ++
Sbjct: 330 AREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNK 389
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ PLH+AA+ H V+E L KH A + + G TA A L G + L+ + G+
Sbjct: 390 DFMTPLHVAAERAHNDVMEVLHKHGA-KMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 448
>5ET1-A nrPDB
Length = 353
Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 38/188 (20%)
Query: 12 AAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRG-ANPDLKDR 68
AAA G L L LL Q V ++ G T L + + G+P++ + LL +G AN +
Sbjct: 78 AAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTD 137
Query: 69 TGFAVIHDAARAGFLDTLQTLL-----------------------------------EFQ 93
TG IH AA G L +L+ L+ E
Sbjct: 138 TGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECS 197
Query: 94 ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVV 153
AD ++ +G PLH AA+ GH V+ +LV + ++H G TA A G +V+
Sbjct: 198 ADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVL 257
Query: 154 SLMQANGA 161
S + +GA
Sbjct: 258 SWLLLHGA 265
Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 37/177 (20%)
Query: 12 AAARGDLEQLTSLLQNNVN-VNAQNGFGRTALQV-MKLGNPEIARRLLLR-GANPDLKDR 68
AAA+GDL L L+ + VNAQ G T L + + G+ E+ + L+ A+P L+ +
Sbjct: 146 AAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQ 205
Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNI--EDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
G +H AA+ G L L+ F ADV+ +D++G +H AA GH +V+ +L+ H
Sbjct: 206 DGMTPLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHG 264
Query: 127 A-------------------------------SNVGHRNHKGDTACDLARLYGRNEV 152
A + + R+H G TA DLA G
Sbjct: 265 AEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHC 321
Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 2/122 (1%)
Query: 41 ALQVMKLGNPEIARRLLLRGA-NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
ALQ + G+ ++ R L G P L+D +H AAR+G L L+ L+E A +
Sbjct: 7 ALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVS 66
Query: 100 D-NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158
G P H AA G+L +++L+ V +++ G T LA +G +VV +
Sbjct: 67 RARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLY 126
Query: 159 NG 160
G
Sbjct: 127 QG 128
Score = 39.3 bits (90), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 2/117 (1%)
Query: 28 NVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTL 86
+V+ + Q+ G TA+ G+ ++ LLL GA +D G +HDAA G L+
Sbjct: 231 DVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS-QDLWGGTPLHDAAENGELECC 289
Query: 87 QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDL 143
Q L A +++ D++G LA GH +L ++ HR D + DL
Sbjct: 290 QILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQTLSLEHRVLSRDQSMDL 346
>3B7B-A nrPDB
Length = 237
Score = 56.6 bits (135), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 46/153 (30%), Positives = 83/153 (54%), Gaps = 7/153 (4%)
Query: 12 AAARGDLEQLTSLLQN-NVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDLKDRT 69
AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++D
Sbjct: 84 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 143
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLR-VVEFLVKHTAS 128
+H AA +G +D + LL + D++ + G+ PLH+AA+E VV FL + S
Sbjct: 144 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR--DS 201
Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+V +N +G+T A L ++V S +Q + A
Sbjct: 202 DVTLKNKEGETPLQCASL--NSQVWSALQMSKA 232
Score = 52.8 bits (125), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 35/114 (30%), Positives = 61/114 (53%)
Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107
G+ +I L+ GAN D + +AA L+ ++ L++ A V+ +D EG+ L
Sbjct: 22 GHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCL 81
Query: 108 HLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
HLAAK+GH VV++L+ + +V ++ G T A Y ++V L+ + G+
Sbjct: 82 HLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 135
Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%)
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
+H AA AG +D L++ A+++ + PL AA+ HL V++L+K + V +
Sbjct: 15 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIK-AGALVDPK 73
Query: 134 NHKGDTACDLARLYGRNEVVSLMQANG 160
+ +G T LA G EVV + +NG
Sbjct: 74 DAEGSTCLHLAAKKGHYEVVQYLLSNG 100
>6BY9-A nrPDB
Length = 328
Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 80/152 (52%), Gaps = 5/152 (3%)
Query: 12 AAARGDLEQLTSLLQN-NVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDLKDRT 69
AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++D
Sbjct: 175 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 234
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129
+H AA +G +D + LL + D++ + G+ PLH+AA+E V + S+
Sbjct: 235 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRD-SD 293
Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
V +N +G+T A L ++V S +Q + A
Sbjct: 294 VTLKNKEGETPLQCASL--NSQVWSALQMSKA 323
Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 43/158 (27%), Positives = 84/158 (53%), Gaps = 3/158 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVN--AQNGFGRTALQVM-KLGNPEIARRLLLRGANP 63
+L +A +G+L+++ +L + ++ N ++ R+ L + G+ +I L+ GAN
Sbjct: 69 KQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI 128
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
D + +AA L+ ++ L++ A V+ +D EG+ LHLAAK+GH VV++L+
Sbjct: 129 DTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLL 188
Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ +V ++ G T A Y ++V L+ + G+
Sbjct: 189 SNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 226
>5HKP-A nrPDB
Length = 351
Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64
+EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+
Sbjct: 26 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 85
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+
Sbjct: 86 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 145
Query: 125 HTASNVGHRNHKGDTACDLA 144
H A H G +A D+A
Sbjct: 146 HGADPTLVNCH-GKSAVDMA 164
Score = 41.6 bits (96), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 4/124 (3%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV----MKLGNPEIARRLLLRGA 61
G+ L AA DL ++ L + Q TAL + ++A LL +GA
Sbjct: 179 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGA 238
Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
N + K++ +H AA D ++ L + A +N D+ G LH AA GHL+
Sbjct: 239 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRL 298
Query: 122 LVKH 125
L+ +
Sbjct: 299 LLSY 302
Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 30/180 (16%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRL--------LLRG 60
L AA++ +E + LL + + N G++A+ + PE+ RL LL+
Sbjct: 128 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAP--TPELRERLTYEFKGHSLLQA 185
Query: 61 AN----PDLKDRTGFAVI-------HDAARAGFLDTL--------QTLLEFQADVNIEDN 101
A +K +I H+ A + +L + LL A+VN ++
Sbjct: 186 AREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNK 245
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ PLH+AA+ H V+E L KH A + + G TA A L G + L+ + G+
Sbjct: 246 DFMTPLHVAAERAHNDVMEVLHKHGA-KMNALDSLGQTALHRAALAGHLQTCRLLLSYGS 304
>4Z68-A nrPDB
Length = 155
Score = 53.5 bits (127), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 64/140 (45%), Gaps = 3/140 (2%)
Query: 8 ELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDL 65
+L AA GD+E + L +VN G T L N + LL GA+
Sbjct: 6 QLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
KD+ G +H+A G + + L++ A VN+ D PLH AA +G + + L++H
Sbjct: 66 KDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQH 125
Query: 126 TASNVGHRNHKGDTACDLAR 145
A +N G+T DL +
Sbjct: 126 GADPTK-KNRDGNTPLDLVK 144
Score = 29.3 bits (64), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Query: 1 MAEPWG-NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEI 52
+A+ W L AAA+G E LLQ+ + +N G T L ++K G+ +I
Sbjct: 98 VADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 150
>1WG0-A nrPDB
Length = 243
Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/127 (31%), Positives = 61/127 (48%), Gaps = 7/127 (5%)
Query: 20 QLTSLL---QNNVNVN-AQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLKDRT--GFA 72
++TS L NVN++ + G T + +GN E+ + L R PDL T G
Sbjct: 50 EITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVT 109
Query: 73 VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132
+H A + + Q L+E A V I+D +PLH AA G L+++E L S V
Sbjct: 110 CLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNW 169
Query: 133 RNHKGDT 139
++ +G T
Sbjct: 170 QDKQGWT 176
Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 6/138 (4%)
Query: 12 AAARGDLEQLTSLLQNNV--NVNAQNGFGRTALQVMKLGNP--EIARRLLLRGANPDLKD 67
A + G+LE + SL + ++N G T L + +G E+++ L+ GA+ +KD
Sbjct: 79 ACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLH-LAVGKKWFEVSQFLIENGASVRIKD 137
Query: 68 RTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
+ +H AA G L ++ L ++ VN +D +G PL A EGH LV+
Sbjct: 138 KFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKY 197
Query: 127 ASNVGHRNHKGDTACDLA 144
+ ++KG A D+A
Sbjct: 198 GAEYDLVDNKGAKAEDVA 215
>3EU9-A nrPDB
Length = 240
Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 4/140 (2%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDLKD 67
L A +G L + L++ + + +G G + + + + G+ I L+ +G + D+ D
Sbjct: 80 LHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMD 139
Query: 68 RTGFAVIHDAA-RAGFLDTLQTLLEFQADVNIEDN-EGNLPLHLAAKEGHLRVVEFLVKH 125
+ G + AA R +D + LL F VN+ D N LH A G+ V+ L++
Sbjct: 140 QNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLE- 198
Query: 126 TASNVGHRNHKGDTACDLAR 145
+NV +N KG++A DLA+
Sbjct: 199 AGANVDAQNIKGESALDLAK 218
Score = 49.7 bits (117), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 39/116 (33%), Positives = 57/116 (49%), Gaps = 3/116 (2%)
Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107
G+ + +L+ GA+P L D G + IH AA+ G + L+ DV++ D G PL
Sbjct: 87 GHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPL 146
Query: 108 HLAAKEGH-LRVVEFLVKHTAS-NVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
AA H + L+ S N+G + HK +TA A L G V+SL+ GA
Sbjct: 147 MWAAYRTHSVDPTRLLLTFNVSVNLGDKYHK-NTALHWAVLAGNTTVISLLLEAGA 201
Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 2/118 (1%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD-L 65
++ A G E+ L++ +V + T L + N ++ + + +GA D L
Sbjct: 12 DIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQL 71
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
+H A R G L + L+++ AD ++ D EG +HLAA+ GH +V +L+
Sbjct: 72 GGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLI 129
Score = 36.2 bits (82), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 2/120 (1%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN-IED 100
++ + G E R L+ G + D+ ++H AA +D ++ + A V+ +
Sbjct: 14 VKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGG 73
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
+ + PLH A ++GHL +V L+K+ A + + +G + LA +G +V+ + A G
Sbjct: 74 DLNSTPLHWATRQGHLSMVVQLMKYGA-DPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG 132
>3UI2-A nrPDB
Length = 244
Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62
PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+
Sbjct: 48 PW----WTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102
Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
D +D R G +H AA + ++ L+E AD+ +ED G L LA
Sbjct: 103 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151
>3DEO-A nrPDB
Length = 183
Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62
PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+
Sbjct: 47 PWW----TAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101
Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
D +D R G +H AA + ++ L+E AD+ +ED G L LA
Sbjct: 102 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
>3EHQ-A nrPDB
Length = 222
Score = 47.4 bits (111), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 30/88 (34%), Positives = 44/88 (50%)
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
+H+AA+ G L L+ L+ + VN D G+ L+ A GH +VE L + +
Sbjct: 77 LHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQQ 136
Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGA 161
N GDTA A G ++V L+ A GA
Sbjct: 137 NKLGDTALHAAAWKGYADIVQLLLAKGA 164
Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61
AE N L AA RG+L L L N V VN + G TAL G + +L
Sbjct: 70 AESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQP 129
Query: 62 NPDL--KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
N +L +++ G +H AA G+ D +Q LL A ++ + E L +A
Sbjct: 130 NIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA 180
>4O1O-A nrPDB
Length = 717
Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Query: 43 QVMKLGNPEIARRLLLRGANPDLKDRT-GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101
Q ++ + E R+LL RGA+ + ++ G++ +H A + D + LL+ AD +
Sbjct: 14 QAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKR 73
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
G P +A G++R+++ L+ + +V + G TA A +YGR E + + NGA
Sbjct: 74 NGATPFIIAGITGNVRLLQLLLPNV-EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGA 132
Score = 44.3 bits (103), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 2/132 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQ-VMKLGNPEIARRLLLRGANPDLK 66
L A D+EQ+ LL+ + N Q +G + L +++ + ++ LL GA+P L+
Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLR 71
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
R G A G + LQ LL DVN D G AA G + + FL ++
Sbjct: 72 KRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENG 131
Query: 127 ASNVGHRNHKGD 138
A HR K D
Sbjct: 132 ADVNMHRKTKQD 143
>6AUN-A nrPDB
Length = 752
Score = 45.1 bits (105), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 4/132 (3%)
Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFA 72
+ +G E + S+ + ++ + +G + L K N E+AR LL RG + D G
Sbjct: 263 SQKGCAEMIISMDSSQIH-SKDPRYGASPLHWAK--NAEMARMLLKRGCDVDSTSAAGNT 319
Query: 73 VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132
+H A D + LL + A+ GN PLHLA + ++ +++ L+ A V
Sbjct: 320 ALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGA-EVDT 378
Query: 133 RNHKGDTACDLA 144
N G+T +A
Sbjct: 379 PNDFGETPAFMA 390
Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/99 (24%), Positives = 46/99 (46%)
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
++ + V H A G + + E+ EG PLHLA ++G ++ LV+
Sbjct: 114 IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQ 173
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGG 163
+ + + ++KG+TA A ++V+ L+ N + G
Sbjct: 174 YCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAG 212
Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
Query: 70 GFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128
G +H A R G + L L+++ A +++ DN+G H A + + +V++ L K+ ++
Sbjct: 152 GCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASA 211
Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLM 156
+ N +G T LA G+ E+V ++
Sbjct: 212 GLNQVNKQGLTPLHLACQMGKQEMVRVL 239
>5DND-A nrPDB
Length = 588
Score = 43.1 bits (100), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRT-ALQVMKLGNPEIARRLLLRG 60
+ P G+ L AR L SL + Q+ + AL + G E + L+ G
Sbjct: 391 SSPPGSTLGQGVAR-----LFSLFGCQEEDSVQDAVMPSLALALAHAGELEALQALMELG 445
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
++ LKD G ++H AAR G + LL DVN D +G PL LA + H +
Sbjct: 446 SDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIR 505
Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGA 164
L K A + ++ K D +L RL R ++ L QA G GA
Sbjct: 506 LLRKAGAC-LSPQDLK-DAGTELCRLASRADMEGL-QAWGQAGA 546
>4OAU-C nrPDB
Length = 699
Score = 43.1 bits (100), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 42/132 (31%), Positives = 60/132 (45%), Gaps = 2/132 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFG-RTALQ-VMKLGNPEIARRLLLRGANPDLK 66
L A D++ + LL+ NVN Q G T L +++ +I LL GA+P L+
Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
+ G AA AG + L+ L ADVN D G AA G ++ ++FL K
Sbjct: 69 KKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 128
Query: 127 ASNVGHRNHKGD 138
A+ R K D
Sbjct: 129 ANVNLRRKTKED 140
>5U0K-A nrPDB
Length = 141
Score = 42.4 bits (98), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 26/81 (32%), Positives = 42/81 (51%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
AA +G + L+ D+ +D + LH+AA EGH+ VV+FL++ N ++
Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRW 91
Query: 137 GDTACDLARLYGRNEVVSLMQ 157
G+ D A + EVV L+Q
Sbjct: 92 GNIPLDDAVQFNHLEVVKLLQ 112
Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLL-LRGANPDLK 66
L AA GD+ L + +++ ++ RTAL V G+ E+ + L+ NP K
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKE 113
DR G + DA + L+ ++ L ++Q + + + +KE
Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTLSETQAEAAAEALSKE 135
>4OT9-A nrPDB
Length = 359
Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 40/120 (33%), Positives = 54/120 (45%), Gaps = 6/120 (5%)
Query: 48 GNPEIARRLLLRGAN--PDL---KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE 102
G PE+ R LL GA P L D G +H A RA + L L++ A+V + +
Sbjct: 167 GAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQ 226
Query: 103 G-NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
G LHLA + L +V LV +NV R G+T LA G + L+ GA
Sbjct: 227 GGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGA 286
Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 11/138 (7%)
Query: 18 LEQLTSLLQNNVN---VNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTGFAV 73
+EQ+ ++ + + VN N +T L + + G + LL GA+P L DR G +
Sbjct: 98 IEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSA 157
Query: 74 IHDAAR--AGFLDTLQTLLEFQAD-----VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
+H A R AG + L+ LL+ A +++ D EG P+HLA + ++ LV
Sbjct: 158 MHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSG 217
Query: 127 ASNVGHRNHKGDTACDLA 144
A G TA LA
Sbjct: 218 AEVEATERQGGRTALHLA 235
Score = 35.8 bits (81), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVK--HTASNVG---HRNHKGDTACDLARLYGRN 150
+ +D G+ PLHLA G V+E +V H A ++G NH T LA + G+
Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134
Query: 151 EVVSLMQANGAGGA 164
VVS + GA A
Sbjct: 135 SVVSFLLRVGADPA 148
>5UQE-A nrPDB
Length = 520
Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/81 (29%), Positives = 41/81 (50%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++
Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483
Query: 137 GDTACDLARLYGRNEVVSLMQ 157
+T D A +G ++V ++Q
Sbjct: 484 NNTPMDEALHFGHHDVFKILQ 504
Score = 30.0 bits (66), Expect = 0.57, Method: Composition-based stats.
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLKDRT 69
AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP KDR
Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104
+ +A G D + L E+Q + + N
Sbjct: 484 NNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 518
>5U0J-A nrPDB
Length = 140
Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 41/81 (50%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++
Sbjct: 31 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 90
Query: 137 GDTACDLARLYGRNEVVSLMQ 157
+T D A +G ++V ++Q
Sbjct: 91 NNTPMDEALHFGHHDVFKILQ 111
Score = 30.4 bits (67), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLL-LRGANPDLK 66
L AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP K
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104
DR + +A G D + L E+Q + + N
Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 125
>6EMK-G nrPDB
Length = 426
Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 8/120 (6%)
Query: 48 GNPEIARRLLLRGANPDL----KDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--IEDN 101
GN I +RLL R NPDL G++ +H A+ G L++ D + I+
Sbjct: 16 GNLLIVKRLLRR--NPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTF 73
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+GN +HLA +GH + + L++ + HR G +A + + +SL+ GA
Sbjct: 74 KGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGA 133
Score = 33.1 bits (74), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 16/54 (29%), Positives = 27/54 (50%)
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
G A IH A + L L+ AD+ + D G+ PLH+ + G + ++ L+
Sbjct: 109 GRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLL 162
>5D68-A nrPDB
Length = 486
Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 1/98 (1%)
Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLP 106
G+ E+ RLL + + D +A IH A G ++ + LLE + + N+ + + + P
Sbjct: 49 GDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 108
Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLA 144
LH AA GH +V+ L+ H ++ + +G + ++
Sbjct: 109 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 146
Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 3/105 (2%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRG-ANPDLK 66
L +A GD E L+ LL +VN + + G E R LL +G NP+L
Sbjct: 42 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 101
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLA 110
+ + +H AA G + +Q LL + D +I D +G PL++
Sbjct: 102 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 146
>3LJN-A nrPDB
Length = 364
Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 18/63 (28%), Positives = 34/63 (53%)
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
D ++ G + +H A + D +E DVN+EDNE +PL+L+ + + + + L+
Sbjct: 205 DYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELL 264
Query: 124 KHT 126
+ T
Sbjct: 265 QKT 267
Score = 32.7 bits (73), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107
G + RRL+ G +P +++R G +H A + G +DT + L ++ G P+
Sbjct: 31 GQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVHSLW--HGQKPI 88
Query: 108 HLAAKEGHLRVVEFLVK 124
HLA +V LV+
Sbjct: 89 HLAVMANKTDLVVALVE 105
Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122
IH AAR G D ++ L+E I++ G LHLA K G + ++L
Sbjct: 24 IHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYL 72
>2KXP-C nrPDB
Length = 118
Score = 35.0 bits (79), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 25/92 (27%), Positives = 42/92 (45%)
Query: 39 RTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI 98
+ + +K G+ + + + +G + + G +H AA G L+ L+ LL AD+N
Sbjct: 4 KEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINA 63
Query: 99 EDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
D PL A EGH+ V+ L+ A
Sbjct: 64 PDKHHITPLLSAVYEGHVSCVKLLLSKGADKT 95
Score = 32.7 bits (73), Expect = 0.072, Method: Compositional matrix adjust.
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 1/98 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDL 65
E A GDL+++ + +VN GR L G EI LLL+GA+ +
Sbjct: 4 KEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINA 63
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103
D+ + A G + ++ LL AD ++ +G
Sbjct: 64 PDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDG 101
Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS-NVGHRNH 135
A + G LD ++ + DVN G PLH AA G L ++EFL+ A N ++H
Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68
Query: 136 KGDTACDLARLY-GRNEVVSLMQANGA 161
L+ +Y G V L+ + GA
Sbjct: 69 ITPL---LSAVYEGHVSCVKLLLSKGA 92
>3ZKJ-A nrPDB
Length = 261
Score = 33.9 bits (76), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 21/59 (35%), Positives = 32/59 (54%)
Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127
+ ++ +H+AA G +L+ L+ VNI + PLH A GHL V+ L+KH A
Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGA 60
Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 1/108 (0%)
Query: 5 WGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
W L +A G + + LLQ+ +V ++ + + G+ E L+ G N D
Sbjct: 69 WHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNID 128
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAK 112
K ++ A ++ LLE ADVN + + PLH A+
Sbjct: 129 HKISHLGTPLYLACENQQRACVKKLLESGADVNQGKGQDS-PLHAVAR 175
Score = 30.0 bits (66), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 4/120 (3%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDL 65
+ L A G L + LL++ VN T L G+ + LL GA+ +
Sbjct: 38 SPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGAS--V 95
Query: 66 KDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
+ + A IH+AAR G ++ + +L+ + +++ + + PL+LA + V+ L++
Sbjct: 96 QPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLE 155
>4BSZ-B nrPDB
Length = 202
Score = 33.5 bits (75), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 14/93 (15%)
Query: 78 ARAGFLDTLQ----TLLEFQADVNIEDNEGN-LPLHLAAKEGHLRVVEFLVKHTA----- 127
ARAG LD+L+ TL+ + +++E + LH+AA GH+ V ++++ +
Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81
Query: 128 ----SNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+ V N G+TA A L G+ +VV L+
Sbjct: 82 EDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 114
Score = 31.2 bits (69), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 10/89 (11%)
Query: 74 IHDAARAGFLDTLQTLLE----------FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
+H AA G ++T++ +LE +A VN + GN LH A+ G L VV+ L
Sbjct: 56 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 115
Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEV 152
++ RN G A A G+ EV
Sbjct: 116 DEYEADPFIRNKFGHDAIFEAENSGKEEV 144
>6BOA-A nrPDB
Length = 742
Score = 32.0 bits (71), Expect = 0.12, Method: Composition-based stats.
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158
PL LAAK+ ++ + L+K+ V R G+TA +A LY E + LM+A
Sbjct: 48 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 101
>6GYM-3 nrPDB
Length = 321
Score = 31.6 bits (70), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 8 ELASAAARGDLEQLTSLLQN----NVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGA- 61
+L ++AR LE+L +L+N N NVN QN + A+ G+ E R L+G+
Sbjct: 217 KLKKSSARRKLEELNRVLKNNPYFNSNVNVQNSRLKDAVPFTPFNGDREAHPRFTLKGSV 276
Query: 62 --NPDLKD 67
+P +KD
Sbjct: 277 YNDPFIKD 284
>6E2G-A nrPDB
Length = 727
Score = 31.2 bits (69), Expect = 0.24, Method: Composition-based stats.
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158
PL LAAKE +++ + L+K V + G+TA +A LY E + LM+A
Sbjct: 48 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEA 101
Score = 30.4 bits (67), Expect = 0.36, Method: Composition-based stats.
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 18/88 (20%)
Query: 38 GRTALQVMKLG-NPEIARRLLLRGANPDLKDRTGFAVIHD---------------AARAG 81
G+TAL + + N + R LL RGA+ + R +V H AA G
Sbjct: 117 GQTALHIAVINQNVNLVRALLARGAS--VSARATGSVFHYRPHNLIYYGEHPLSFAACVG 174
Query: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHL 109
+ ++ L+E AD+ +D+ GN LH+
Sbjct: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHI 202
Score = 26.9 bits (58), Expect = 4.2, Method: Composition-based stats.
Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIH----DAARAGFLDTLQTLLEFQADVNIE--- 99
+G+ EI R L+ GA+ +D G V+H + LL + +++
Sbjct: 173 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLE 232
Query: 100 ---DNEGNLPLHLAAKEGHLRVVEFLVK 124
+N+G P LA EG++ + + L++
Sbjct: 233 LVPNNQGLTPFKLAGVEGNIVMFQHLMQ 260
>2ISQ-A nrPDB
Length = 320
Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 7/59 (11%)
Query: 52 IARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
+A +L + +KDR GF++I DA + G + +++L IE GN + LA
Sbjct: 30 VAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVL-------IEPTSGNTGVGLA 81
>1DCQ-A nrPDB
Length = 278
Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 15 RGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG-ANPDLKDRTGFAV 73
R L + L+QN+ N++ Q G G TAL L + +LLLRG A+ ++ + +G
Sbjct: 182 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP 241
Query: 74 IHDAAR 79
+ A R
Sbjct: 242 LDIAKR 247
>4AEC-A nrPDB
Length = 430
Score = 30.8 bits (68), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 52 IARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
IA +L + +KDR G++++ DA + GF+ +++L +E GN + LA
Sbjct: 140 IAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVL-------VEPTSGNTGIGLA 191
>3T9K-A nrPDB
Length = 390
Score = 30.8 bits (68), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%)
Query: 18 LEQLTSLLQNNVNVNAQNGFGRTALQVMKL--GNPEIARRLLLR-GANPDLKDRTGFAVI 74
L + L + +VN NG A +++ N +A LL+ GAN + D G +
Sbjct: 213 LPTMADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPL 272
Query: 75 HDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122
H A G L+ AD+ D+EG PL +A + + +V L
Sbjct: 273 HHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320
Score = 30.0 bits (66), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
A A L + LL+ A+VN D+ G PLH A GH + +K A ++G R+ +
Sbjct: 242 ATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGA-DLGARDSE 300
Query: 137 GDTACDLARLYGRNEVVSLMQ 157
G +A ++V+L++
Sbjct: 301 GRDPLTIAMETANADIVTLLR 321
Score = 27.3 bits (59), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDLKD 67
L A A L LLQN NVN + GR L LG+ +A L RGA+ +D
Sbjct: 239 LIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARD 298
Query: 68 RTG 70
G
Sbjct: 299 SEG 301
>2RFA-A nrPDB
Length = 232
Score = 30.8 bits (68), Expect = 0.32, Method: Compositional matrix adjust.
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158
PL LAAKE ++ + L+K V R G+TA +A LY E + LM+A
Sbjct: 6 PLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEA 59
Score = 27.7 bits (60), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 18/88 (20%)
Query: 38 GRTALQVMKLG-NPEIARRLLLRGANPDLKDRTGFAVIHD---------------AARAG 81
G+TAL + + N + R LL RGA+ + R +V H AA G
Sbjct: 75 GQTALHIAVINQNVNLVRALLARGAS--VSARATGSVFHYRPHNLIYYGEHPLSFAACVG 132
Query: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHL 109
+ ++ L+E AD+ +D+ GN LH+
Sbjct: 133 SEEIVRLLIEHGADIRAQDSLGNTVLHI 160
>4LMA-A nrPDB
Length = 326
Score = 30.4 bits (67), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 23/91 (25%)
Query: 22 TSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANP--DLKDRTGFAVIHDAAR 79
T L+Q N A+ GR VMKL G NP +KDR G +I+ A +
Sbjct: 21 TPLVQLNRIPQAEGCLGRI---VMKL-----------EGMNPAASVKDRIGTHMINSAEK 66
Query: 80 AGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
AG ++ T+L +E GN + LA
Sbjct: 67 AGLINPETTVL-------VEPTSGNTGIALA 90
>3LVQ-E nrPDB
Length = 497
Score = 30.0 bits (66), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+GN LH AA ++ L+K A VG N G+TA D+AR E L++ A
Sbjct: 206 DGNTALHYAALYNQPDCLKLLLKGRAL-VGTVNEAGETALDIARKKHHKECEELLEQAQA 264
Query: 162 G 162
G
Sbjct: 265 G 265
>5WP0-A nrPDB
Length = 279
Score = 30.0 bits (66), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 125 HTASNV-GHRNHKGDTACDLARLYGRNE 151
H+A N+ G GD ACDLA L+G N+
Sbjct: 171 HSAENITGFYTKFGDGACDLAPLFGLNK 198
>2B0O-E nrPDB
Length = 301
Score = 29.6 bits (65), Expect = 0.69, Method: Compositional matrix adjust.
Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%)
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+GN LH AA ++ L+K A VG N G+TA D+AR E L++ A
Sbjct: 225 DGNTALHYAALYNQPDCLKLLLKGRAL-VGTVNEAGETALDIARKKHHKECEELLEQAQA 283
Query: 162 G 162
G
Sbjct: 284 G 284
>6DMR-A nrPDB
Length = 730
Score = 29.6 bits (65), Expect = 0.70, Method: Composition-based stats.
Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 21/121 (17%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGF-----GRTALQVMKLG-NPEIARRLLLRGAN 62
L AA +LE T L++ + + G+TAL + + N + R LL RGA+
Sbjct: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
Query: 63 PDLKDRTGFAV--------------IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLH 108
+ TG A + AA G + ++ L+E AD+ +D+ GN LH
Sbjct: 143 VSAR-ATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201
Query: 109 L 109
+
Sbjct: 202 I 202
>6CUD-A nrPDB
Length = 806
Score = 29.6 bits (65), Expect = 0.73, Method: Composition-based stats.
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 51 EIARRLLLRGANPDLKDRTGFAVIH-----DAARAGFLDTLQTLLEFQADVNIE--DNEG 103
E RR +RG DR DAA G + ++ +LE +N+ D G
Sbjct: 3 EKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMG 62
Query: 104 NLPLHLAAKEGHLRVVEFLVK 124
L LA HL V E L+K
Sbjct: 63 QNALQLAVGNEHLEVTELLLK 83
>3Q4G-A nrPDB
Length = 279
Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 125 HTASNV-GHRNHKGDTACDLARLYGRNE 151
H+A N+ G GD ACDLA L+G N+
Sbjct: 171 HSAENITGFYTKFGDGACDLAPLFGLNK 198
>1W5T-A nrPDB
Length = 412
Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust.
Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 19 EQLTSLLQNNVNVNAQNGFGRT----------ALQVMKLGNPEIARRLLLRGANPDLKDR 68
E L +LL+ + + +++G R AL M+ P++ ++ + P K R
Sbjct: 159 EDLYTLLRVHEEIPSRDGVNRIGFLLVASDVRALSYMREKIPQVESQIGFKLHLPAYKSR 218
Query: 69 TGFAVIHDAARAGFLDTLQTL--LEFQADVNIEDNEGN 104
+ ++ A G DT+ LE +DV ED G+
Sbjct: 219 ELYTILEQRAELGLRDTVWEPRHLELISDVYGEDKGGD 256
>6CV9-A nrPDB
Length = 842
Score = 29.3 bits (64), Expect = 0.88, Method: Composition-based stats.
Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 3/59 (5%)
Query: 76 DAARAGFLDTLQTLLE--FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV-KHTASNVG 131
DAA G + ++ +LE +VN D G L LA HL + E L+ K S VG
Sbjct: 15 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73
Score = 26.9 bits (58), Expect = 4.6, Method: Composition-based stats.
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 7/94 (7%)
Query: 42 LQVMKLGNPEIARRLL--LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
L + GN + R++L N + D G + A L+ + LL+ + +
Sbjct: 14 LDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
D L LA +G++R+VE ++ H A G R
Sbjct: 74 D-----ALLLAISKGYVRIVEAILNHPAFAEGKR 102
>1XLT-A nrPDB
Length = 384
Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 16/48 (33%), Positives = 20/48 (41%), Gaps = 8/48 (16%)
Query: 103 GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN 150
GN PL K +VKH VGH N A D + L+ +N
Sbjct: 299 GNCPLSEPGK--------IVVKHGVKIVGHTNVPSRVAADASPLFAKN 338
>4QJ1-A nrPDB
Length = 361
Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
Query: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLP 106
+G EI R LL A D+ ++ D+A L+ ++TL E ++ +NI+ GN+
Sbjct: 102 IGVNEIERAKLLVEAGVDV-------IVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVV 154
Query: 107 LHLAAKE 113
A KE
Sbjct: 155 TEEATKE 161
>6DJS-A nrPDB
Length = 676
Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats.
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 51 EIARRLLLRGANPDLKDRTGFAVIH-----DAARAGFLDTLQTLLEFQADVNIE--DNEG 103
E RR +RG DR DAA G + ++ +LE +N+ D G
Sbjct: 20 EKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMG 79
Query: 104 NLPLHLAAKEGHLRVVEFLVK 124
L LA HL V E L+K
Sbjct: 80 QNALQLAVGNEHLEVTELLLK 100
>3T4P-A nrPDB
Length = 334
Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 13/100 (13%)
Query: 26 QNNVNVNAQNGFGRT-ALQVMKLGNPEIARRLLLRGANP--DLKDRTGFAVIHDAARAGF 82
NV + G+T AL + KL N + L + NP +KDR GFA+ A + G
Sbjct: 8 SKNVAQSIDQLIGQTPALYLNKLNNTKAKVVLKMECENPMASVKDRLGFAIYDKAEKEGK 67
Query: 83 LDTLQTLLEFQADVNIEDNEGNLPL---HLAAKEGHLRVV 119
L ++++ +E + GN + HL A G+ ++
Sbjct: 68 LIPGKSIV-------VESSSGNTGVSLAHLGAIRGYKVII 100
>3FFS-A nrPDB
Length = 400
Score = 28.1 bits (61), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
Query: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLP 106
+G EI R LL A D+ ++ D+A L+ ++TL E ++ +NI+ GN+
Sbjct: 141 IGVNEIERAKLLVEAGVDV-------IVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVV 193
Query: 107 LHLAAKE 113
A KE
Sbjct: 194 TEEATKE 200
>2NYJ-A nrPDB
Length = 273
Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 14/39 (35%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 103 GNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDT 139
G LPL LAA L +V+FL++++ +++ R+ G+T
Sbjct: 148 GELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNT 186
>5IRX-A nrPDB
Length = 636
Score = 28.1 bits (61), Expect = 1.9, Method: Composition-based stats.
Identities = 14/39 (35%), Positives = 25/39 (64%), Gaps = 2/39 (5%)
Query: 103 GNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDT 139
G LPL LAA L +V+FL++++ +++ R+ G+T
Sbjct: 143 GELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNT 181
>4LMB-A nrPDB
Length = 322
Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 9/55 (16%)
Query: 58 LRGANP--DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
L NP +KDR G +++ DA AG + +T+L +E GN + LA
Sbjct: 43 LESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTIL-------VEPTSGNTGIALA 90
>4LG1-A nrPDB
Length = 224
Score = 27.3 bits (59), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 17 DLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN 49
DLE+L LL+ N+N+N G +V+K G
Sbjct: 91 DLEELQDLLKMNINMNKHLVTGSVQAKVLKWGE 123
>6ED3-A nrPDB
Length = 848
Score = 26.9 bits (58), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 4/85 (4%)
Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLD---TLQTLLEFQADVNIEDNEGN 104
G+ ++A+ L GA+P R F + +AR + T Q L ++ D+ EG
Sbjct: 118 GDSDVAKLLTGHGASPQAL-REAFVKVRGSARVTSPEPEATYQALQKYSTDLTARAREGK 176
Query: 105 LPLHLAAKEGHLRVVEFLVKHTASN 129
L + RVV+ L + T +N
Sbjct: 177 LDPVIGRDNEIRRVVQVLSRRTKNN 201
>6DVZ-A nrPDB
Length = 791
Score = 26.9 bits (58), Expect = 4.8, Method: Composition-based stats.
Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 16/102 (15%)
Query: 37 FGRTALQVMKLGN-PEIARRLLLRGANPDL--KDRTGFAVIHD--------AARAGFLDT 85
FG T L + N PEI + LL+ D+ +D G ++H + F+
Sbjct: 261 FGETPLALAACTNQPEIVQ-LLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKR 319
Query: 86 LQTLLEFQAD----VNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
+ ++ ++ + +N+G PL LAAK G ++++++
Sbjct: 320 MYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYIL 361
>5XE7-A nrPDB
Length = 312
Score = 26.6 bits (57), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNA-QNGFGRTALQVMKLGNPEIARRLL 57
L +A A GDL+ + SLL +V NG TA++ ++ G+ ++ R +L
Sbjct: 184 LMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVR-GSDKVVRFIL 232
>3AUJ-A nrPDB
Length = 554
Score = 26.2 bits (56), Expect = 7.0, Method: Composition-based stats.
Identities = 11/28 (39%), Positives = 15/28 (53%)
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQ 93
K+R G V+ A+ GF D Q +L Q
Sbjct: 466 KNRNGLEVVKALAQGGFTDVAQDMLNIQ 493
>4XD0-A nrPDB
Length = 417
Score = 26.2 bits (56), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 54/121 (44%), Gaps = 5/121 (4%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65
+E+ +A E ++ LL+ + +N G + + + GN ++ L+ +G N +
Sbjct: 293 DEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNIND 352
Query: 66 KDRTGFAV---IHDAA-RAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
++ G V D R+G L+ L+ D+ ++DNEG K ++ + F
Sbjct: 353 RNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNF 412
Query: 122 L 122
+
Sbjct: 413 M 413
>2RON-A nrPDB
Length = 242
Score = 26.2 bits (56), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGF 37
AEP G+ +A DLE+LT L + +N+ F
Sbjct: 45 AEPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPF 80
>6BO5-A nrPDB
Length = 695
Score = 25.8 bits (55), Expect = 8.3, Method: Composition-based stats.
Identities = 11/31 (35%), Positives = 19/31 (61%)
Query: 98 IEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128
I +++G PL LAAKEG + + +++ S
Sbjct: 250 ISNHQGLTPLKLAAKEGKIEIFRHILQREFS 280
>5HI9-A nrPDB
Length = 770
Score = 25.8 bits (55), Expect = 8.3, Method: Composition-based stats.
Identities = 11/31 (35%), Positives = 19/31 (61%)
Query: 98 IEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128
I +++G PL LAAKEG + + +++ S
Sbjct: 290 ISNHQGLTPLKLAAKEGKIEIFRHILQREFS 320
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
1G3N-B nrPDB 204 2e-53
5AQB-A nrPDB 197 1e-51
5AQ9-A nrPDB 197 2e-51
5MIO-C nrPDB 187 3e-48
6MWQ-A nrPDB 183 3e-47
5AQA-A nrPDB 182 7e-47
6FES-A nrPDB 179 4e-46
5H76-A nrPDB 178 1e-45
5AQ7-A nrPDB 166 3e-42
1BLX-B nrPDB 158 1e-39
1BD8-A nrPDB 154 2e-38
6BY9-A nrPDB 153 3e-38
3B7B-A nrPDB 150 2e-37
4Z68-A nrPDB 150 3e-37
5CBO-A nrPDB 150 4e-37
4OAU-C nrPDB 145 7e-36
5JHQ-A nrPDB 142 6e-35
3EU9-A nrPDB 142 8e-35
5HKP-A nrPDB 141 1e-34
5GP7-A nrPDB 140 2e-34
4NIK-A nrPDB 139 6e-34
2DWZ-A nrPDB 138 7e-34
4O1O-A nrPDB 130 3e-31
6AUN-A nrPDB 130 3e-31
1WG0-A nrPDB 128 1e-30
2A5E-A nrPDB 126 3e-30
6EMK-G nrPDB 124 2e-29
5ET1-A nrPDB 122 7e-29
4OT9-A nrPDB 122 8e-29
5DND-A nrPDB 121 2e-28
1D9S-A nrPDB 117 3e-27
5D68-A nrPDB 111 1e-25
3EHQ-A nrPDB 106 6e-24
5UQE-A nrPDB 98 2e-21
3UI2-A nrPDB 96 7e-21
3DEO-A nrPDB 95 2e-20
5U0K-A nrPDB 93 4e-20
5U0J-A nrPDB 92 8e-20
Sequences not found previously or not previously below threshold:
3ZKJ-A nrPDB 98 2e-21
2KXP-C nrPDB 88 2e-18
6E2G-A nrPDB 84 2e-17
3LJN-A nrPDB 80 5e-16
6DMR-A nrPDB 76 6e-15
3T9K-A nrPDB 76 7e-15
2RFA-A nrPDB 76 9e-15
6BOA-A nrPDB 75 2e-14
4BSZ-B nrPDB 73 8e-14
3LVQ-E nrPDB 65 1e-11
6DVZ-A nrPDB 65 2e-11
4N5Q-A nrPDB 64 3e-11
2B0O-E nrPDB 63 7e-11
1DCQ-A nrPDB 62 1e-10
6CUD-A nrPDB 60 4e-10
5IRX-A nrPDB 60 4e-10
6CV9-A nrPDB 60 5e-10
6DJS-A nrPDB 60 6e-10
6OO7-A nrPDB 59 1e-09
2NYJ-A nrPDB 58 1e-09
5UIL-A nrPDB 58 1e-09
5AN8-A nrPDB 58 2e-09
6BO5-A nrPDB 56 7e-09
5HI9-A nrPDB 56 7e-09
6G1K-A nrPDB 53 4e-08
6C8G-A nrPDB 53 5e-08
6BBJ-A nrPDB 53 5e-08
2ETB-A nrPDB 53 6e-08
2F37-A nrPDB 52 1e-07
4XD0-A nrPDB 51 2e-07
3W9G-A nrPDB 51 2e-07
6MHW-A nrPDB 48 2e-06
4DX2-A nrPDB 48 2e-06
5Z96-A nrPDB 46 9e-06
4CJ9-A nrPDB 31 0.29
3LJQ-A nrPDB 31 0.36
4WVX-A nrPDB 29 1.3
2DI3-A nrPDB 28 2.2
1HXH-A nrPDB 28 2.2
5Z56-q nrPDB 27 3.4
4LG8-A nrPDB 27 3.4
5XE7-A nrPDB 27 3.7
1JI6-A nrPDB 26 5.6
1KKT-A nrPDB 26 5.7
>1G3N-B nrPDB
Length = 168
Score = 204 bits (519), Expect = 2e-53, Method: Composition-based stats.
Identities = 168/168 (100%), Positives = 168/168 (100%)
Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60
MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG
Sbjct: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE
Sbjct: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168
FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ
Sbjct: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168
>5AQB-A nrPDB
Length = 428
Score = 197 bits (502), Expect = 1e-51, Method: Composition-based stats.
Identities = 56/155 (36%), Positives = 85/155 (54%), Gaps = 1/155 (0%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65
G +L AA G ++ L+ N +VNA + G T L + G+ EI LL GA+ +
Sbjct: 15 GKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVNA 74
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
D G+ +H AA +G L+ ++ LL++ ADVN +D G PLHLAA GHL +VE L+K+
Sbjct: 75 ADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKN 134
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
A +V ++ G T DLA G ++ ++
Sbjct: 135 GA-DVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAA 168
Score = 148 bits (374), Expect = 9e-37, Method: Composition-based stats.
Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 2/126 (1%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
G+ L+ + G + R L+ GA+ + D G+ +H AA G L+ ++ LL+ AD
Sbjct: 13 DLGKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGAD 71
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
VN D +G PLHLAA GHL +VE L+K+ A +V + G T LA ++G E+V +
Sbjct: 72 VNAADIDGYTPLHLAAFSGHLEIVEVLLKYGA-DVNADDQAGFTPLHLAAIFGHLEIVEV 130
Query: 156 MQANGA 161
+ NGA
Sbjct: 131 LLKNGA 136
Score = 90.8 bits (224), Expect = 3e-19, Method: Composition-based stats.
Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 5/112 (4%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA G LE + LL+ +VNA + G T L + G+ EI LL GA+ + +
Sbjct: 82 PLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQ 141
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRV 118
D+ G A G D + L + V ++D L A+ G++ +
Sbjct: 142 DKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAADQ----LGARVGYIEL 189
>5AQ9-A nrPDB
Length = 422
Score = 197 bits (501), Expect = 2e-51, Method: Composition-based stats.
Identities = 62/158 (39%), Positives = 90/158 (56%), Gaps = 2/158 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D
Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K
Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 134
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
H A +V ++ G T DLA G ++V +L+Q A
Sbjct: 135 HGA-DVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAA 171
Score = 158 bits (401), Expect = 7e-40, Method: Composition-based stats.
Identities = 47/126 (37%), Positives = 70/126 (55%), Gaps = 1/126 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ AD
Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 72
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
V+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V +
Sbjct: 73 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYLEIVEV 131
Query: 156 MQANGA 161
+ +GA
Sbjct: 132 LLKHGA 137
Score = 137 bits (346), Expect = 2e-33, Method: Composition-based stats.
Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 1/123 (0%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLK 66
L AA G LE + LL++ +V+A + FG T L + G+ EI LL GA+ +
Sbjct: 50 PLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAM 109
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D G +H AA+ G+L+ ++ LL+ ADVN +D G P LA G+ V L
Sbjct: 110 DSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAA 169
Query: 127 ASN 129
A++
Sbjct: 170 AAD 172
Score = 84.2 bits (207), Expect = 3e-17, Method: Composition-based stats.
Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 1/103 (0%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA G LE + LL+N +VNA + G T L + G EI LL GA+ + +
Sbjct: 83 PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQ 142
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHL 109
D+ G A G D L A + G + L L
Sbjct: 143 DKFGKTPFDLADDNGNDDVGTLLQVAAAADQLGARVGYIELDL 185
>5MIO-C nrPDB
Length = 573
Score = 187 bits (474), Expect = 3e-48, Method: Composition-based stats.
Identities = 56/154 (36%), Positives = 83/154 (53%), Gaps = 2/154 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+
Sbjct: 411 GKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVS 470
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G +H AA G L+ ++ LL+ ADVN D G+ PL LAA GHL++VE L+K
Sbjct: 471 ASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLK 530
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158
H A +V ++ G TA D + G ++ ++Q
Sbjct: 531 HGA-DVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563
Score = 162 bits (411), Expect = 6e-41, Method: Composition-based stats.
Identities = 46/126 (36%), Positives = 70/126 (55%), Gaps = 1/126 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
G+ L+ + G + R L+ GA+ + D +G +H AA G L+ ++ LL+ AD
Sbjct: 409 DLGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGAD 468
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
V+ D G+ PLHLAA GHL +VE L+KH A +V + GDT LA + G ++V
Sbjct: 469 VSASDLMGSTPLHLAALIGHLEIVEVLLKHGA-DVNAVDTWGDTPLRLAAVMGHLKIVEA 527
Query: 156 MQANGA 161
+ +GA
Sbjct: 528 LLKHGA 533
Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats.
Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA G LE + LL++ +VNA + +G T L++ +G+ +I LL GA+ + +
Sbjct: 479 PLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQ 538
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQ 93
D+ G + G D + L +
Sbjct: 539 DKFGKTAYDTSIDNGSEDLAEILQKLN 565
>6MWQ-A nrPDB
Length = 493
Score = 183 bits (465), Expect = 3e-47, Method: Composition-based stats.
Identities = 58/154 (37%), Positives = 88/154 (57%), Gaps = 2/154 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + FG T L + + G+ EI LL GA+ +
Sbjct: 6 GKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVN 65
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G +H AA AG L+ ++ LL++ ADVN D G PLHL A +GHL +VE L+K
Sbjct: 66 AADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLK 125
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158
H A +V ++ G TA D++ G ++ ++Q
Sbjct: 126 HGA-DVNAQDKFGKTAFDISIDNGNEDLAEILQK 158
Score = 157 bits (397), Expect = 2e-39, Method: Composition-based stats.
Identities = 46/126 (36%), Positives = 69/126 (54%), Gaps = 1/126 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
G+ L+ + G + R L+ GA+ + DR G +H AA+ G L+ ++ LL+ AD
Sbjct: 4 DLGKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGAD 63
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
VN D G PLHLAA GHL +VE L+K+ A +V + G T L + G E+V +
Sbjct: 64 VNAADLWGQTPLHLAATAGHLEIVEVLLKYGA-DVNALDLIGKTPLHLTAIDGHLEIVEV 122
Query: 156 MQANGA 161
+ +GA
Sbjct: 123 LLKHGA 128
Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats.
Identities = 43/127 (33%), Positives = 65/127 (51%), Gaps = 1/127 (0%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA RG LE + LL+ +VNA + +G+T L + G+ EI LL GA+ +
Sbjct: 41 PLHLAAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNAL 100
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D G +H A G L+ ++ LL+ ADVN +D G ++ G+ + E L K
Sbjct: 101 DLIGKTPLHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLN 160
Query: 127 ASNVGHR 133
S++ HR
Sbjct: 161 LSDIAHR 167
>5AQA-A nrPDB
Length = 418
Score = 182 bits (462), Expect = 7e-47, Method: Composition-based stats.
Identities = 56/155 (36%), Positives = 83/155 (53%), Gaps = 2/155 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D
Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+ +VE L+K
Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLK 134
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
A +V ++ G LA G E+ + + A
Sbjct: 135 AGA-DVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168
Score = 157 bits (398), Expect = 2e-39, Method: Composition-based stats.
Identities = 47/126 (37%), Positives = 69/126 (54%), Gaps = 1/126 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ AD
Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 72
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
V+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V +
Sbjct: 73 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYKEIVEV 131
Query: 156 MQANGA 161
+ GA
Sbjct: 132 LLKAGA 137
>6FES-A nrPDB
Length = 367
Score = 179 bits (455), Expect = 4e-46, Method: Composition-based stats.
Identities = 55/151 (36%), Positives = 76/151 (50%), Gaps = 2/151 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ LL N +VN + G T L + G+ I LL GA+ +
Sbjct: 7 GKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 66
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G +H AA G L+ ++ LL+ A VN D G PLHLAA GH +VE L+K
Sbjct: 67 ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLK 126
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
+ A + ++ G T DLAR G V L
Sbjct: 127 NGA-DARAQDKFGKTPEDLARDNGYESVARL 156
Score = 161 bits (408), Expect = 1e-40, Method: Composition-based stats.
Identities = 49/126 (38%), Positives = 69/126 (54%), Gaps = 1/126 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ AD
Sbjct: 5 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 64
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
VN D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V +
Sbjct: 65 VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-VNATDVIGTAPLHLAAMWGHEEIVEV 123
Query: 156 MQANGA 161
+ NGA
Sbjct: 124 LLKNGA 129
Score = 106 bits (266), Expect = 4e-24, Method: Composition-based stats.
Identities = 41/89 (46%), Positives = 54/89 (60%), Gaps = 1/89 (1%)
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
+ +AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V
Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNAN 68
Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGAG 162
+ +G T LA G E+V ++ NGAG
Sbjct: 69 DERGHTPLHLAAYTGHLEIVEVLLKNGAG 97
Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats.
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLR 59
L AA G E + LL+N + AQ+ FG+T + + E RL +
Sbjct: 108 PLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARLARK 159
>5H76-A nrPDB
Length = 201
Score = 178 bits (452), Expect = 1e-45, Method: Composition-based stats.
Identities = 57/152 (37%), Positives = 86/152 (56%), Gaps = 3/152 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D
Sbjct: 7 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 66
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K
Sbjct: 67 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 126
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
H A V ++ G TA D++ G ++ ++
Sbjct: 127 HGA--VNAQDKFGKTAFDISIDNGNEDLAQIL 156
Score = 151 bits (382), Expect = 1e-37, Method: Composition-based stats.
Identities = 48/131 (36%), Positives = 72/131 (54%), Gaps = 1/131 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ AD
Sbjct: 5 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 64
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
V+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V +
Sbjct: 65 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYLEIVEV 123
Query: 156 MQANGAGGATN 166
+ +GA A +
Sbjct: 124 LLKHGAVNAQD 134
Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats.
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 2/86 (2%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA G LE + LL+N +VNA + G T L + G EI LL GA + +
Sbjct: 75 PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VNAQ 133
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92
D+ G + G D Q L +
Sbjct: 134 DKFGKTAFDISIDNGNEDLAQILAFY 159
>5AQ7-A nrPDB
Length = 418
Score = 166 bits (421), Expect = 3e-42, Method: Composition-based stats.
Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 2/155 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ LL N +VN + G T L + G+ I LL GA+ +
Sbjct: 15 GKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 74
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D G +H AA G L+ ++ LL+ A VN D G PLHLAA G+ +VE L+K
Sbjct: 75 ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLK 134
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
A +V ++ G LA G E+ + + A
Sbjct: 135 AGA-DVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168
Score = 152 bits (383), Expect = 8e-38, Method: Composition-based stats.
Identities = 48/126 (38%), Positives = 68/126 (53%), Gaps = 1/126 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ AD
Sbjct: 13 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 72
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
VN D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V +
Sbjct: 73 VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-VNATDVIGTAPLHLAAMWGYKEIVEV 131
Query: 156 MQANGA 161
+ GA
Sbjct: 132 LLKAGA 137
Score = 101 bits (253), Expect = 1e-22, Method: Composition-based stats.
Identities = 41/89 (46%), Positives = 54/89 (60%), Gaps = 1/89 (1%)
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
+ +AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V
Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNAN 76
Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGAG 162
+ +G T LA G E+V ++ NGAG
Sbjct: 77 DERGHTPLHLAAYTGHLEIVEVLLKNGAG 105
>1BLX-B nrPDB
Length = 166
Score = 158 bits (400), Expect = 1e-39, Method: Composition-based stats.
Identities = 72/155 (46%), Positives = 106/155 (68%), Gaps = 3/155 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+P +A LL +GA+P+
Sbjct: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPN 68
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
++D +G + +HDAAR GFLDTL+ L+E ADVN D+ G+LP+HLA +EGH VV FL
Sbjct: 69 VQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL-- 126
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
S++ HR+ G T +LAR G ++ ++Q +
Sbjct: 127 APESDLHHRDASGLTPLELARQRGAQNLMDILQGH 161
Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats.
Identities = 18/86 (20%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 77 AARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135
AA G + ++ LL + + + G L + G V L+K AS ++
Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALELLKQGASP-NVQDA 72
Query: 136 KGDTACDLARLYGRNEVVSLMQANGA 161
G + A G + + ++ +GA
Sbjct: 73 SGTSPVHDAARTGFLDTLKVLVEHGA 98
>1BD8-A nrPDB
Length = 156
Score = 154 bits (390), Expect = 2e-38, Method: Composition-based stats.
Identities = 71/155 (45%), Positives = 104/155 (67%), Gaps = 3/155 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+ IA LL +GA+P+
Sbjct: 3 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 62
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
++D +G + +HDAAR GFLDTL+ L+E ADVN+ D G LP+HLA +EGH VV FL
Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL-- 120
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
S++ R+ +G T +LA G ++V ++Q +
Sbjct: 121 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGH 155
Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats.
Identities = 17/86 (19%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 77 AARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135
AA G + ++ LL + + + G L + G + L+K AS ++
Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASP-NVQDT 66
Query: 136 KGDTACDLARLYGRNEVVSLMQANGA 161
G + A G + + ++ +GA
Sbjct: 67 SGTSPVHDAARTGFLDTLKVLVEHGA 92
>6BY9-A nrPDB
Length = 328
Score = 153 bits (387), Expect = 3e-38, Method: Composition-based stats.
Identities = 44/155 (28%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 9 LASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDLK 66
L AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++
Sbjct: 172 LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIR 231
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D +H AA +G +D + LL + D++ + G+ PLH+AA+E V +
Sbjct: 232 DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR- 290
Query: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
S+V +N +G+T A L ++V S +Q + A
Sbjct: 291 DSDVTLKNKEGETPLQCASL--NSQVWSALQMSKA 323
Score = 129 bits (324), Expect = 6e-31, Method: Composition-based stats.
Identities = 43/158 (27%), Positives = 83/158 (52%), Gaps = 3/158 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQ--NGFGRTALQVMK-LGNPEIARRLLLRGANP 63
+L +A +G+L+++ +L + ++ N + + R+ L G+ +I L+ GAN
Sbjct: 69 KQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI 128
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
D + +AA L+ ++ L++ A V+ +D EG+ LHLAAK+GH VV++L+
Sbjct: 129 DTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLL 188
Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ +V ++ G T A Y ++V L+ + G+
Sbjct: 189 SNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 226
Score = 33.4 bits (75), Expect = 0.048, Method: Composition-based stats.
Identities = 11/44 (25%), Positives = 18/44 (40%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN 49
+ L AA + + L + +V +N G T LQ L +
Sbjct: 269 DSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNS 312
>3B7B-A nrPDB
Length = 237
Score = 150 bits (380), Expect = 2e-37, Method: Composition-based stats.
Identities = 44/155 (28%), Positives = 81/155 (52%), Gaps = 5/155 (3%)
Query: 9 LASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDLK 66
L AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++
Sbjct: 81 LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIR 140
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D +H AA +G +D + LL + D++ + G+ PLH+AA+E V +
Sbjct: 141 DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR- 199
Query: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
S+V +N +G+T A L ++V S +Q + A
Sbjct: 200 DSDVTLKNKEGETPLQCASL--NSQVWSALQMSKA 232
Score = 116 bits (292), Expect = 3e-27, Method: Composition-based stats.
Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 3/156 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDL 65
+ L +AA G ++ L+Q N++ + RT L + + + E + L+ GA D
Sbjct: 13 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 72
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
KD G +H AA+ G + +Q LL DVN +D+ G P+ A + H+ +V+ L+
Sbjct: 73 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 132
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
S++ R+++ + A G ++ ++ A
Sbjct: 133 KG-SDINIRDNEENICLHWAAFSGCVDIAEILLAAK 167
Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats.
Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 36 GFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA 94
R+ L G+ +I L+ GAN D + +AA L+ ++ L++ A
Sbjct: 9 QNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGA 68
Query: 95 DVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVS 154
V+ +D EG+ LHLAAK+GH VV++L+ + +V ++ G T A Y ++V
Sbjct: 69 LVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVK 128
Query: 155 LMQANGA 161
L+ + G+
Sbjct: 129 LLLSKGS 135
Score = 33.0 bits (74), Expect = 0.067, Method: Composition-based stats.
Identities = 11/44 (25%), Positives = 18/44 (40%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN 49
+ L AA + + L + +V +N G T LQ L +
Sbjct: 178 DSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNS 221
Score = 26.8 bits (58), Expect = 4.1, Method: Composition-based stats.
Identities = 5/33 (15%), Positives = 11/33 (33%)
Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
N + + A G ++ ++ GA
Sbjct: 3 NFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGA 35
>4Z68-A nrPDB
Length = 155
Score = 150 bits (379), Expect = 3e-37, Method: Composition-based stats.
Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 6 GNELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANP 63
+L AA GD+E + L +VN G T L N + LL GA+
Sbjct: 4 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
KD+ G +H+A G + + L++ A VN+ D PLH AA +G + + L+
Sbjct: 64 HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLL 123
Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+H A + +N G+T DL + G ++ L+
Sbjct: 124 QHGA-DPTKKNRDGNTPLDLVKD-GDTDIQDLL 154
Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats.
Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 4/125 (3%)
Query: 39 RTALQVMKLGNPEIARRLLLRGANPDLKDRTG--FAVIHDAARAGFLDTLQTLLEFQADV 96
R L+ K G+ E ++L + + +D G +H AA + ++ LL+ ADV
Sbjct: 5 RQLLEAAKAGDVETVKKLCTVQS-VNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63
Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+ +D G +PLH A GH V E LVKH A V + T A G+ E+ L+
Sbjct: 64 HAKDKGGLVPLHNACSYGHYEVAELLVKHGAV-VNVADLWKFTPLHEAAAKGKYEICKLL 122
Query: 157 QANGA 161
+GA
Sbjct: 123 LQHGA 127
>5CBO-A nrPDB
Length = 176
Score = 150 bits (378), Expect = 4e-37, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 70/129 (54%), Gaps = 1/129 (0%)
Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95
G+ L+ G + R L+ GA+ + D G +H AA G + ++ LL++ AD
Sbjct: 2 DLGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61
Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155
VN D G+ PLHLAAK G+L +VE L+K+ A +V ++ G TA D++ G ++ +
Sbjct: 62 VNASDATGDTPLHLAAKWGYLGIVEVLLKYGA-DVNAQDKFGKTAFDISIDNGNEDLAEI 120
Query: 156 MQANGAGGA 164
+ N A A
Sbjct: 121 LCKNKAQQA 129
Score = 135 bits (340), Expect = 9e-33, Method: Composition-based stats.
Identities = 42/123 (34%), Positives = 66/123 (53%), Gaps = 1/123 (0%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64
G +L AA G +++ L+ N +VNA + FG T L + G+ EI LL GA+ +
Sbjct: 4 GKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVN 63
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
D TG +H AA+ G+L ++ LL++ ADVN +D G ++ G+ + E L K
Sbjct: 64 ASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCK 123
Query: 125 HTA 127
+ A
Sbjct: 124 NKA 126
>4OAU-C nrPDB
Length = 699
Score = 145 bits (367), Expect = 7e-36, Method: Composition-based stats.
Identities = 48/160 (30%), Positives = 69/160 (43%), Gaps = 11/160 (6%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFG-RTALQ-VMKLGNPEIARRLLLRGANPDLK 66
L A D++ + LL+ NVN Q G T L +++ +I LL GA+P L+
Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
+ G AA AG + L+ L ADVN D G AA G ++ ++FL K
Sbjct: 69 KKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 128
Query: 127 ASNVGHRNHK---------GDTACDLARLYGRNEVVSLMQ 157
A+ R K G TA A G EV+ ++
Sbjct: 129 ANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 168
Score = 110 bits (276), Expect = 3e-25, Method: Composition-based stats.
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTG-FAVIHDAARAGFLDTLQTLLEFQADVNIED 100
++ ++ + ++ ++LL GAN + ++ G + +H+A + D ++ LL AD +
Sbjct: 10 IKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRK 69
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
G P LAA G +++++ + A +V + G TA A +YG+ + + + G
Sbjct: 70 KNGATPFILAAIAGSVKLLKLFLSKGA-DVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 128
Query: 161 A 161
A
Sbjct: 129 A 129
Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats.
Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 15/169 (8%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L +A + + LL++ + + G T + G+ ++ + L +GA+ +
Sbjct: 42 PLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNEC 101
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE----------GNLPLHLAAKEGHL 116
D GF +AA G + L+ L + A+VN+ G L AA++GH+
Sbjct: 102 DFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHV 161
Query: 117 RVVEFLVKHTASNVGHRNHKGDTACDLARL----YGRNEVVSLMQANGA 161
V++ L+ ++V ++ G A A L + L+ +GA
Sbjct: 162 EVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGA 210
Score = 106 bits (265), Expect = 4e-24, Method: Composition-based stats.
Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 49/200 (24%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTA-LQVMKLGNPEIARRLLLRGANPDLKDRT- 69
AA G ++ L L +VN + +G TA ++ G + + L RGAN +L+ +T
Sbjct: 79 AAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTK 138
Query: 70 ---------GFAVIHDAARAGFLDTLQ--------------------------------- 87
G + DAA G ++ L+
Sbjct: 139 EDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDV 198
Query: 88 -----TLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142
LL+ ADVN+ G PL LA ++ HL +V+ L++ + + G TA
Sbjct: 199 EAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALL 258
Query: 143 LARLYGRNEVVSLMQANGAG 162
LA ++ L+ GA
Sbjct: 259 LAVELKLKKIAELLCKRGAS 278
Score = 95.4 bits (236), Expect = 1e-20, Method: Composition-based stats.
Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 13/160 (8%)
Query: 9 LASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTAL-QVMKLGNPEIAR----RLLLRGAN 62
L AA +G +E L LL +VNA + GR AL + + LL GA+
Sbjct: 152 LMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGAD 211
Query: 63 PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA-DVNIEDNEGNLPLHLAAKEGHLRVVEF 121
+++ G + A L +Q LLE + ++N D++G L LA + ++ E
Sbjct: 212 VNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAEL 271
Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
L K AS GD R Y + +V ++ ++GA
Sbjct: 272 LCKRGAST-----DCGDLVMTARRNYDHS-LVKVLLSHGA 305
Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats.
Identities = 13/55 (23%), Positives = 24/55 (43%)
Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
L A + + +V+ L++ A+ G T A R ++V L+ +GA
Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGA 63
>5JHQ-A nrPDB
Length = 482
Score = 142 bits (359), Expect = 6e-35, Method: Composition-based stats.
Identities = 54/170 (31%), Positives = 79/170 (46%), Gaps = 11/170 (6%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGR--TALQ-VMKLGNPEIARRLLLRGANP 63
EL A GD+ ++ L+ + NVNA++ GR + L G ++ LL GAN
Sbjct: 17 RELLEACRNGDVSRVKRLV-DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV 75
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
+D G +H+A G + + LL AD N DN PLH AA +G + V L+
Sbjct: 76 HARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 135
Query: 124 KHTASNVGHRNHKGDTACDL------ARLYGRNEVVSLMQANGAGGATNL 167
+H A + RN G +A DL A L G + L++A +G L
Sbjct: 136 QHGA-DPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKL 184
Score = 141 bits (355), Expect = 1e-34, Method: Composition-based stats.
Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64
+EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+
Sbjct: 170 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 229
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+
Sbjct: 230 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 289
Query: 125 HTASNVGHRNHKGDTACDLA 144
H A H G +A D+A
Sbjct: 290 HGADPTLVNCH-GKSAVDMA 308
Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats.
Identities = 53/216 (24%), Positives = 82/216 (37%), Gaps = 56/216 (25%)
Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLR 59
MA + L AA G + + LLQ NV+A++ G L G+ E+ LL +
Sbjct: 45 MAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQ 104
Query: 60 GANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ----------------ADV------- 96
GA+P+ +D + +H+AA G +D LL+ AD
Sbjct: 105 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLT 164
Query: 97 -------------------------------NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+ D + PLHLAA +R+V+ L++H
Sbjct: 165 GEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 224
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
A +V ++ G A YG EV L+ +GA
Sbjct: 225 GA-DVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA 259
Score = 120 bits (302), Expect = 2e-28, Method: Composition-based stats.
Identities = 52/177 (29%), Positives = 75/177 (42%), Gaps = 25/177 (14%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL---------------------QVMK 46
L AA +G ++ LLQ+ + N +N G++AL + +
Sbjct: 118 PLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAAR 177
Query: 47 LGNPEIARRLLLRGANPDLKDRTG--FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104
GN E LL N + G +H AA + +Q LL+ ADV+ +D G
Sbjct: 178 SGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGL 236
Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+PLH A GH V E L+KH A V + T A R EV SL+ ++GA
Sbjct: 237 VPLHNACSYGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGA 292
Score = 98.5 bits (244), Expect = 1e-21, Method: Composition-based stats.
Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 9/158 (5%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL----GNPEIARRLLLRGA 61
G+ L AA DL ++ L + Q TAL ++ LL +GA
Sbjct: 323 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 382
Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
N + K++ +H AA D ++ L + A +N D G LH AA GHL+
Sbjct: 383 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 442
Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
L+ + S+ + +G T A G V ++ +
Sbjct: 443 LLSYG-SDPSIISLQGFT----AAQMGNEAVQQILSES 475
Score = 91.2 bits (225), Expect = 2e-19, Method: Composition-based stats.
Identities = 47/212 (22%), Positives = 75/212 (35%), Gaps = 59/212 (27%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGAN---- 62
L +A + G E LL++ VNA + + T L N E+ LL GA+
Sbjct: 238 PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 297
Query: 63 -------------PDLKDR-------------------------------------TGFA 72
P+L++R +
Sbjct: 298 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 357
Query: 73 VIHDAARAGFLD---TLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129
+H A + + LL A+VN ++ + PLH+AA+ H V+E L KH A
Sbjct: 358 ALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK- 416
Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ + G TA A L G + L+ + G+
Sbjct: 417 MNALDTLGQTALHRAALAGHLQTCRLLLSYGS 448
>3EU9-A nrPDB
Length = 240
Score = 142 bits (358), Expect = 8e-35, Method: Composition-based stats.
Identities = 41/158 (25%), Positives = 74/158 (46%), Gaps = 4/158 (2%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLK 66
L A +G L + L++ + + +G G + + + + G+ I L+ +G + D+
Sbjct: 79 PLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMM 138
Query: 67 DRTGFAVIHDAARAGF-LDTLQTLLEFQADVNIEDN-EGNLPLHLAAKEGHLRVVEFLVK 124
D+ G + AA +D + LL F VN+ D N LH A G+ V+ L++
Sbjct: 139 DQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLE 198
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
A NV +N KG++A DLA+ +++ +Q
Sbjct: 199 AGA-NVDAQNIKGESALDLAKQRKNVWMINHLQEARQA 235
Score = 116 bits (290), Expect = 6e-27, Method: Composition-based stats.
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 3/156 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQN-GFGRTALQVM-KLGNPEIARRLLLRGANPDLK 66
L AA ++ + + V+ T L + G+ + +L+ GA+P L
Sbjct: 46 LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLI 105
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGH-LRVVEFLVKH 125
D G + IH AA+ G + L+ DV++ D G PL AA H + L+
Sbjct: 106 DGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTF 165
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
S + +TA A L G V+SL+ GA
Sbjct: 166 NVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGA 201
Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats.
Identities = 36/153 (23%), Positives = 66/153 (43%), Gaps = 4/153 (2%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD-L 65
++ A G E+ L++ +V + T L + N ++ + + +GA D L
Sbjct: 12 DIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQL 71
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+H A R G L + L+++ AD ++ D EG +HLAA+ GH +V +L+
Sbjct: 72 GGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK 131
Query: 126 TASNVGHRNHKGDTACDLARLYGRN-EVVSLMQ 157
+V + G T A + + L+
Sbjct: 132 G-QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 163
Score = 84.2 bits (207), Expect = 2e-17, Method: Composition-based stats.
Identities = 30/128 (23%), Positives = 59/128 (46%), Gaps = 2/128 (1%)
Query: 35 NGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA 94
+ ++ + G E R L+ G + D+ ++H AA +D ++ + A
Sbjct: 7 DYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGA 66
Query: 95 DVNIEDNE-GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVV 153
V+ + + PLH A ++GHL +V L+K+ A + + +G + LA +G +V
Sbjct: 67 IVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGA-DPSLIDGEGCSCIHLAAQFGHTSIV 125
Query: 154 SLMQANGA 161
+ + A G
Sbjct: 126 AYLIAKGQ 133
>5HKP-A nrPDB
Length = 351
Score = 141 bits (356), Expect = 1e-34, Method: Composition-based stats.
Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%)
Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64
+EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+
Sbjct: 26 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 85
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+
Sbjct: 86 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 145
Query: 125 HTASNVGHRNHKGDTACDLA 144
H A H G +A D+A
Sbjct: 146 HGADPTLVNCH-GKSAVDMA 164
Score = 105 bits (262), Expect = 9e-24, Method: Composition-based stats.
Identities = 41/122 (33%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTG--FAVIHDAARAGFLDTLQTLLEFQADVNIE 99
L+ + GN E LL N + G +H AA + +Q LL+ ADV+ +
Sbjct: 29 LEAARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 87
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
D G +PLH A GH V E L+KH A V + T A R EV SL+ ++
Sbjct: 88 DKGGLVPLHNACSYGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNRVEVCSLLLSH 146
Query: 160 GA 161
GA
Sbjct: 147 GA 148
Score = 99.6 bits (247), Expect = 5e-22, Method: Composition-based stats.
Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 9/158 (5%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL----GNPEIARRLLLRGA 61
G+ L AA DL ++ L + Q TAL ++A LL +GA
Sbjct: 179 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGA 238
Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
N + K++ +H AA D ++ L + A +N D+ G LH AA GHL+
Sbjct: 239 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRL 298
Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
L+ + S+ + +G T A G V ++ +
Sbjct: 299 LLSYG-SDPSIISLQGFT----AAQMGNEAVQQILSES 331
Score = 90.4 bits (223), Expect = 3e-19, Method: Composition-based stats.
Identities = 47/212 (22%), Positives = 75/212 (35%), Gaps = 59/212 (27%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGAN---- 62
L +A + G E LL++ VNA + + T L N E+ LL GA+
Sbjct: 94 PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 153
Query: 63 -------------PDLKDR-------------------------------------TGFA 72
P+L++R +
Sbjct: 154 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 213
Query: 73 VIHDAARAGFLD---TLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129
+H A + + LL A+VN ++ + PLH+AA+ H V+E L KH A
Sbjct: 214 ALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK- 272
Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ + G TA A L G + L+ + G+
Sbjct: 273 MNALDSLGQTALHRAALAGHLQTCRLLLSYGS 304
Score = 77.3 bits (189), Expect = 3e-15, Method: Composition-based stats.
Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 2/89 (2%)
Query: 74 IHDAARAGFLDTLQTLLE-FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132
+ +AAR+G + L LL + + D + PLHLAA +R+V+ L++H A +V
Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGA-DVHA 86
Query: 133 RNHKGDTACDLARLYGRNEVVSLMQANGA 161
++ G A YG EV L+ +GA
Sbjct: 87 KDKGGLVPLHNACSYGHYEVTELLLKHGA 115
>5GP7-A nrPDB
Length = 169
Score = 140 bits (354), Expect = 2e-34, Method: Composition-based stats.
Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 3/138 (2%)
Query: 9 LASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L AA +G L ++ L N+N G T L + N E+A LL GA+ + +
Sbjct: 13 LLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 72
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D+ G +H+AA G +D L+++ VN D PLH AA++G ++ L+ H
Sbjct: 73 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHG 132
Query: 127 ASNVGHRNHKGDTACDLA 144
A + +N +G T DLA
Sbjct: 133 A-DPTMKNQEGQTPLDLA 149
Score = 91.6 bits (226), Expect = 2e-19, Method: Composition-based stats.
Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 1/106 (0%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLK 66
L AA +LE LL++ +VNAQ+ G L G+ +IA L+ +
Sbjct: 46 PLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNAT 105
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAK 112
D+ F +H+AA+ G LL AD +++ EG PL LA
Sbjct: 106 DKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATA 151
Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats.
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 4/62 (6%)
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGD--TACDLARLYGRNEVVSLMQAN 159
G+ L AAK+G L V+ L N+ R+ +G T LA Y EV + +
Sbjct: 8 RGDAALLDAAKKGCLARVQKLCT--PENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEH 65
Query: 160 GA 161
GA
Sbjct: 66 GA 67
>4NIK-A nrPDB
Length = 230
Score = 139 bits (350), Expect = 6e-34, Method: Composition-based stats.
Identities = 45/155 (29%), Positives = 76/155 (49%), Gaps = 2/155 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKD 67
L A + G E + LLQ V VN ++ G + L + G EI + LL +GA + +
Sbjct: 48 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 107
Query: 68 RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127
+ G +H AA + LLE A+ + +D+ +H AA +G+L+++ L+ + A
Sbjct: 108 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 167
Query: 128 SNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
S ++ +G+T LA R E L+ + GA
Sbjct: 168 S-TNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 201
Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats.
Identities = 54/140 (38%), Positives = 69/140 (49%), Gaps = 2/140 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDL 65
+ L AA+ G E + +LL VNA N G T L N EIA LL GANPD
Sbjct: 79 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 138
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
KD +H AA G L + LL ++A NI+D EGN PLHLA E + + LV
Sbjct: 139 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 198
Query: 126 TASNVGHRNHKGDTACDLAR 145
AS + N + T +A+
Sbjct: 199 GAS-IYIENKEEKTPLQVAK 217
Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats.
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 5/158 (3%)
Query: 13 AARGDLEQLT-SLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTG 70
A G LE+L S+L + + RTAL G+ EI LL G + KD G
Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 77
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
++ +H AA AG + ++ LL A VN + G PLH AA + + L++ +N
Sbjct: 78 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANP 136
Query: 131 GHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168
++H TA A G +++ ++ A +TN+Q
Sbjct: 137 DAKDHYEATAMHRAAAKGNLKMIHILLYYKA--STNIQ 172
Score = 31.1 bits (69), Expect = 0.25, Method: Composition-based stats.
Identities = 13/51 (25%), Positives = 23/51 (45%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLL 58
L A +E+ L+ ++ +N +T LQV K G I +R++
Sbjct: 179 PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVE 229
>2DWZ-A nrPDB
Length = 231
Score = 138 bits (349), Expect = 7e-34, Method: Composition-based stats.
Identities = 43/155 (27%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKD 67
L A + G E + LLQ V VN ++ G + L + G EI + LL++GA+ + +
Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVN 103
Query: 68 RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127
+ G +H AA + LLE A+ + +D+ +H AA +G+L++V L+
Sbjct: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILL-FYK 162
Query: 128 SNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
++ ++ +G+T LA R E + GA
Sbjct: 163 ASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGAS 197
Score = 135 bits (339), Expect = 1e-32, Method: Composition-based stats.
Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 2/140 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDL 65
+ L AA+ G E + +LL +VNA N G T L N EIA LL GANPD
Sbjct: 75 SPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
KD +H AA G L + LL ++A NI+D EGN PLHLA E + +FLV
Sbjct: 135 KDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQ 194
Query: 126 TASNVGHRNHKGDTACDLAR 145
AS + N + T +A+
Sbjct: 195 GAS-IYIENKEEKTPLQVAK 213
Score = 116 bits (291), Expect = 5e-27, Method: Composition-based stats.
Identities = 46/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%)
Query: 13 AARGDLEQLT-SLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTG 70
A G L++L +L + + RTAL G+ EI LL G + KD G
Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
++ +H AA AG + ++ LL A VN + G PLH AA + + L++ +N
Sbjct: 74 WSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANP 132
Query: 131 GHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168
++H TA A G ++V ++ A +TN+Q
Sbjct: 133 DAKDHYDATAMHRAAAKGNLKMVHILLFYKA--STNIQ 168
Score = 31.5 bits (70), Expect = 0.16, Method: Composition-based stats.
Identities = 14/51 (27%), Positives = 22/51 (43%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLL 58
L A +E+ L+ ++ +N +T LQV K G I +RL
Sbjct: 175 PLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAE 225
>4O1O-A nrPDB
Length = 717
Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats.
Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 11/160 (6%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVM-KLGNPEIARRLLLRGANPDLK 66
L A D+EQ+ LL+ + N Q +G + L ++ + ++ LL GA+P L+
Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLR 71
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
R G A G + LQ LL DVN D G AA G + + FL ++
Sbjct: 72 KRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENG 131
Query: 127 ASNVGHRNHK---------GDTACDLARLYGRNEVVSLMQ 157
A HR K G TA A G VV+++
Sbjct: 132 ADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILL 171
Score = 114 bits (286), Expect = 2e-26, Method: Composition-based stats.
Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Query: 43 QVMKLGNPEIARRLLLRGANPDLKDRT-GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101
Q ++ + E R+LL RGA+ + ++ G++ +H A + D + LL+ AD +
Sbjct: 14 QAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKR 73
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
G P +A G++R+++ L+ + +V + G TA A +YGR E + + NGA
Sbjct: 74 NGATPFIIAGITGNVRLLQLLLPNV-EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGA 132
Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats.
Identities = 48/175 (27%), Positives = 79/175 (45%), Gaps = 16/175 (9%)
Query: 3 EPWG-NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRG 60
E WG + L SA + + LL++ + + G T + + GN + + LL
Sbjct: 39 EEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKRNGATPFIIAGITGNVRLLQLLLPNV 98
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI-----EDNE-----GNLPLHLA 110
+ + D GF +AA G ++ L+ L E ADVN+ +D E G L A
Sbjct: 99 EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDA 158
Query: 111 AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLY---GRNE-VVSLMQANGA 161
A++GH+ VV L+ + V R++ G A A L G+ + + L+ +GA
Sbjct: 159 AEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGA 213
Score = 99.6 bits (247), Expect = 5e-22, Method: Composition-based stats.
Identities = 46/200 (23%), Positives = 73/200 (36%), Gaps = 49/200 (24%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTA-LQVMKLGNPEIARRLLLRGANPDL----- 65
A G++ L LL N +VN + G TA ++ G E R L GA+ ++
Sbjct: 82 AGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTK 141
Query: 66 KD-----RTGFAVIHDAARAGFLDTL---------------------------------- 86
+D + G + DAA G + +
Sbjct: 142 QDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKA 201
Query: 87 ----QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142
+ LL+ ADVN+ PL LA + +L +V+ L++ V + +G TA
Sbjct: 202 KAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALL 261
Query: 143 LARLYGRNEVVSLMQANGAG 162
LA E+ L+ GA
Sbjct: 262 LAVELRLEEIAKLLCHRGAS 281
Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats.
Identities = 23/123 (18%), Positives = 41/123 (33%), Gaps = 11/123 (8%)
Query: 22 TSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLKDRTGFAVIHDAAR 79
LL + +VN + +T L + N ++ + LL + + DR G + A
Sbjct: 206 RLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVE 265
Query: 80 AGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHL--RVVEFLVKHTASNVGHRNHKG 137
+ + L A N D +A + +V+FL H A +
Sbjct: 266 LRLEEIAKLLCHRGASTNCGDL-------VAIARRNYDSDLVKFLRLHKAGEDFRPPAEN 318
Query: 138 DTA 140
Sbjct: 319 WKP 321
>6AUN-A nrPDB
Length = 752
Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats.
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 7/145 (4%)
Query: 4 PWGNELASA---AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60
P G + +A + +G E + S+ + ++ + +G + L K N E+AR LL RG
Sbjct: 251 PSGFPIHTAMKFSQKGCAEMIISMDSSQIH-SKDPRYGASPLHWAK--NAEMARMLLKRG 307
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
+ D G +H A D + LL + A+ GN PLHLA + ++ +++
Sbjct: 308 CDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIK 367
Query: 121 FLVKHTASNVGHRNHKGDTACDLAR 145
L+ A V N G+T +A
Sbjct: 368 ALIVFGA-EVDTPNDFGETPAFMAS 391
Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats.
Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 8/157 (5%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN-PDL 65
L A G E + LL N N G + MK A ++ ++
Sbjct: 223 PLHLACQMGKQEMVRVLLLCNARCNVMGPSGF-PIHTAMKFSQKGCAEMIISMDSSQIHS 281
Query: 66 KD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
KD R G + +H A + + LL+ DV+ GN LH+A V L+
Sbjct: 282 KDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLT 338
Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ A N G G+T LA E++ + GA
Sbjct: 339 YGA-NAGTPGEHGNTPLHLAISKDNMEMIKALIVFGA 374
Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats.
Identities = 40/195 (20%), Positives = 70/195 (35%), Gaps = 41/195 (21%)
Query: 8 ELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN--PD 64
L A +GD E L L+Q + ++ + G TA G+ +LL + A+ +
Sbjct: 155 PLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLN 214
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIED------------------------ 100
++ G +H A + G + ++ LL A N+
Sbjct: 215 QVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAEMIISM 274
Query: 101 ----------NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN 150
G PLH A + + L+K +V + G+TA +A + R
Sbjct: 275 DSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRG-CDVDSTSAAGNTALHVAVMRNRF 330
Query: 151 EVVSLMQANGAGGAT 165
+ V ++ GA T
Sbjct: 331 DCVMVLLTYGANAGT 345
Score = 87.7 bits (216), Expect = 2e-18, Method: Composition-based stats.
Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 1/96 (1%)
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+ G +H A R G + L L+++ A +++ DN+G H A + + +V++ L K+
Sbjct: 149 NEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKN 208
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
++ + N +G T LA G+ E+V ++ A
Sbjct: 209 ASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNA 244
Score = 80.4 bits (197), Expect = 3e-16, Method: Composition-based stats.
Identities = 37/177 (20%), Positives = 58/177 (32%), Gaps = 46/177 (25%)
Query: 35 NGFGRTALQVMK-LGNPEIARRLLLR-GANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF 92
N G T L + G+ EI L+ A D+ D G H A + LQ L +
Sbjct: 149 NEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKN 208
Query: 93 Q-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLV---------------------------- 123
A +N + +G PLHLA + G +V L+
Sbjct: 209 ASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCA 268
Query: 124 ----KHTASNVGHRN-HKGDTACDLARLYGRNEVVSLMQANG-------AGGATNLQ 168
+S + ++ G + A+ E+ ++ G A G T L
Sbjct: 269 EMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCDVDSTSAAGNTALH 322
Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats.
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 1/110 (0%)
Query: 54 RRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKE 113
+L ++ ++ + V H A G + + E+ EG PLHLA ++
Sbjct: 104 VEVLQHLSDL-IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRK 162
Query: 114 GHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGG 163
G ++ LV++ + + ++KG+TA A ++V+ L+ N + G
Sbjct: 163 GDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAG 212
>1WG0-A nrPDB
Length = 243
Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats.
Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 6/158 (3%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVN---AQNGFGRTALQVMK-LGNPEIARRLLLRGANP 63
L + + E + LL NVN + G T + +GN E+ + L R P
Sbjct: 39 PLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKP 98
Query: 64 DLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
DL T G +H A + + Q L+E A V I+D +PLH AA G L+++E
Sbjct: 99 DLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIEL 158
Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
L S V ++ +G T A G + L+
Sbjct: 159 LCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEK 196
Score = 88.5 bits (218), Expect = 1e-18, Method: Composition-based stats.
Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 7/156 (4%)
Query: 8 ELASAAARGDLEQLTSLLQN--NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64
A + G+LE + SL ++N G T L + E+++ L+ GA+
Sbjct: 75 PFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVR 134
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-VNIEDNEGNLPLHLAAKEGHLRVVEFLV 123
+KD+ +H AA G L ++ L VN +D +G PL A EGH LV
Sbjct: 135 IKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLV 194
Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
+ + ++KG A D+A +V N
Sbjct: 195 EKYGAEYDLVDNKGAKAEDVAL---NEQVKKFFLNN 227
Score = 74.2 bits (181), Expect = 2e-14, Method: Composition-based stats.
Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 6/128 (4%)
Query: 41 ALQVMKLGNP--EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI 98
L + N ++ L + + KD+ G +H + + LL +VN+
Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64
Query: 99 EDN---EGNLPLHLAAKEGHLRVVEFLVKHT-ASNVGHRNHKGDTACDLARLYGRNEVVS 154
+D G P H+A G+L VV+ L ++ ++G T LA EV
Sbjct: 65 DDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQ 124
Query: 155 LMQANGAG 162
+ NGA
Sbjct: 125 FLIENGAS 132
Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats.
Identities = 19/90 (21%), Positives = 35/90 (38%), Gaps = 3/90 (3%)
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNI-EDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129
+H A +Q LL + + + +D +G +PLH + + FL+ +
Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENV 62
Query: 130 V--GHRNHKGDTACDLARLYGRNEVVSLMQ 157
+ + G T +A G EVV +
Sbjct: 63 NLDDYPDDSGWTPFHIACSVGNLEVVKSLY 92
>2A5E-A nrPDB
Length = 156
Score = 126 bits (318), Expect = 3e-30, Method: Composition-based stats.
Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%)
Query: 3 EPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN 62
EP + LA+AAARG +E++ +LL+ NA N +GR +QVM +G+ +A LLL GA
Sbjct: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAE 69
Query: 63 PDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
P+ D +HDAAR GFLDTL L A +++ D G LP+ LA + GH V +
Sbjct: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129
Query: 122 LVKHTASNVGHRNHKGDTA 140
L G + + D A
Sbjct: 130 LRAAAGGTRGSNHARIDAA 148
Score = 70.8 bits (172), Expect = 3e-13, Method: Composition-based stats.
Identities = 34/120 (28%), Positives = 47/120 (39%), Gaps = 3/120 (2%)
Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103
G E R LL GA P+ + G I G + LL A+ N D
Sbjct: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRPIQV-MMMGSARVAELLLLHGAEPNCADPAT 77
Query: 104 NL-PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
P+H AA+EG L + L + A + R+ G DLA G +V ++A G
Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGAR-LDVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136
>6EMK-G nrPDB
Length = 426
Score = 124 bits (311), Expect = 2e-29, Method: Composition-based stats.
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 4/118 (3%)
Query: 48 GNPEIARRLLLRGANP--DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--IEDNEG 103
GN I +RLL R + ++ G++ +H A+ G L++ D + I+ +G
Sbjct: 16 GNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKG 75
Query: 104 NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
N +HLA +GH + + L++ + HR G +A + + +SL+ GA
Sbjct: 76 NTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGA 133
Score = 87.3 bits (215), Expect = 3e-18, Method: Composition-based stats.
Identities = 33/169 (19%), Positives = 65/169 (38%), Gaps = 10/169 (5%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGF--GRTALQVMKLGNPEIARRLLLR 59
+E + L A+ G L+Q + + G T + + + E LLL+
Sbjct: 37 SENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQ 96
Query: 60 GAN--PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLR 117
+ + G A IH A + L L+ AD+ + D G+ PLH+ + G +
Sbjct: 97 QFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSIS 156
Query: 118 VVEFLVKHTASNV--GHRNHKGDTACDLA----RLYGRNEVVSLMQANG 160
++ L+ ++ R+ D+A ++V+ ++ G
Sbjct: 157 CMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKKKG 205
>5ET1-A nrPDB
Length = 353
Score = 122 bits (306), Expect = 7e-29, Method: Composition-based stats.
Identities = 48/196 (24%), Positives = 80/196 (40%), Gaps = 38/196 (19%)
Query: 10 ASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGA------ 61
AAA G L L LL Q V ++ G T L + + G+P++ + LL +G
Sbjct: 76 HDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAIT 135
Query: 62 -----------------------------NPDLKDRTGFAVIHDAARAGFLDTLQTLL-E 91
+ + G ++ A + G L+ + L+ E
Sbjct: 136 TDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQE 195
Query: 92 FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE 151
AD ++ +G PLH AA+ GH V+ +LV + ++H G TA A G +
Sbjct: 196 CSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTK 255
Query: 152 VVSLMQANGAGGATNL 167
V+S + +GA + +L
Sbjct: 256 VLSWLLLHGAEISQDL 271
Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats.
Identities = 52/160 (32%), Positives = 79/160 (49%), Gaps = 8/160 (5%)
Query: 8 ELASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLR-GANPD 64
+ AAA+GDL L L+ VNAQ G T L + G+ E+ + L+ A+P
Sbjct: 142 PIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPH 201
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--IEDNEGNLPLHLAAKEGHLRVVEFL 122
L+ + G +H AA+ G L L+ F ADV+ +D++G +H AA GH +V+ +L
Sbjct: 202 LRAQDGMTPLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGHTKVLSWL 260
Query: 123 VKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
+ H A ++ G T A G E ++ NGAG
Sbjct: 261 LLHGAEI--SQDLWGGTPLHDAAENGELECCQILAVNGAG 298
Score = 98.1 bits (243), Expect = 1e-21, Method: Composition-based stats.
Identities = 41/154 (26%), Positives = 60/154 (38%), Gaps = 5/154 (3%)
Query: 6 GNELASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
L A G LE L+ + + + + + G T L L+ A+
Sbjct: 174 ATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVS 233
Query: 65 L--KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122
+D G +H AA G L LL A+++ D G PLH AA+ G L + L
Sbjct: 234 FSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQ-DLWGGTPLHDAAENGELECCQIL 292
Query: 123 VKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+ A + R+H G TA DLA G +
Sbjct: 293 AVNGAG-LDVRDHDGYTAADLAEFNGHTHCSRYL 325
Score = 87.3 bits (215), Expect = 3e-18, Method: Composition-based stats.
Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 4/157 (2%)
Query: 7 NELASAAARGDLEQLTSLLQNNV-NVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPD 64
+ AA RGDL+ L SL + + ++ + + G R L+ A P
Sbjct: 5 EQALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPA 64
Query: 65 L-KDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122
+ + R G HDAA G+L LQ LL V +DN G LHLAA+ GH VV++L
Sbjct: 65 VSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWL 124
Query: 123 VKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
+ +N G A G + L+ +
Sbjct: 125 LYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGH 161
Score = 84.6 bits (208), Expect = 2e-17, Method: Composition-based stats.
Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Query: 41 ALQVMKLGNPEIARRLLLRGA-NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI- 98
ALQ + G+ ++ R L G P L+D +H AAR+G L L+ L+E A +
Sbjct: 7 ALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVS 66
Query: 99 EDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158
G P H AA G+L +++L+ V +++ G T LA +G +VV +
Sbjct: 67 RARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLY 126
Query: 159 NGAGGA 164
G +
Sbjct: 127 QGGANS 132
Score = 80.4 bits (197), Expect = 4e-16, Method: Composition-based stats.
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
Query: 8 ELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65
L +AA G L L+ +V+ + Q+ G TA+ G+ ++ LLL GA
Sbjct: 210 PLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEI-S 268
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+D G +HDAA G L+ Q L A +++ D++G LA GH +L
Sbjct: 269 QDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTV 328
Query: 126 TASNVGHRNHKGDTACDL 143
++ HR D + DL
Sbjct: 329 QTLSLEHRVLSRDQSMDL 346
>4OT9-A nrPDB
Length = 359
Score = 122 bits (306), Expect = 8e-29, Method: Composition-based stats.
Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 9/163 (5%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM---KLGNPEIARRLLLRGAN-- 62
L A G ++ LL+ + + G +A+ + G PE+ R LL GA
Sbjct: 124 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAV 183
Query: 63 ---PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG-NLPLHLAAKEGHLRV 118
+ D G +H A RA + L L++ A+V + +G LHLA + L +
Sbjct: 184 PQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGL 243
Query: 119 VEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
V LV +NV R G+T LA G + L+ GA
Sbjct: 244 VTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGA 286
Score = 84.6 bits (208), Expect = 2e-17, Method: Composition-based stats.
Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 14/154 (9%)
Query: 22 TSLLQNNVNV-NAQNGFGRTALQVM----KLGNPEIARRLLLRGAN---PDLKDRTGFAV 73
+LL ++ AQ+ G T L + + E ++ + +L +
Sbjct: 65 RALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTP 124
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA--AKEGHLRVVEFLVKHTASNV- 130
+H A G + LL AD + D G+ +HLA A G ++ L++ A V
Sbjct: 125 LHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVP 184
Query: 131 ---GHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ +G LA E + L+ +GA
Sbjct: 185 QLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGA 218
Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 3/103 (2%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVM-KLGNPEIARRLLLR-GANPD 64
+ A E L L+ + V A GRTAL + ++ + L+ + AN +
Sbjct: 197 PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVN 256
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107
+ G +H AA G+ + LL+ AD++ E+ E PL
Sbjct: 257 ARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299
Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats.
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 5/86 (5%)
Query: 84 DTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV-----KHTASNVGHRNHKGD 138
D L + + +D G+ PLHLA G V+E +V V NH
Sbjct: 63 DARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQ 122
Query: 139 TACDLARLYGRNEVVSLMQANGAGGA 164
T LA + G+ VVS + GA A
Sbjct: 123 TPLHLAVITGQTSVVSFLLRVGADPA 148
>5DND-A nrPDB
Length = 588
Score = 121 bits (303), Expect = 2e-28, Method: Composition-based stats.
Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 9/164 (5%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRT-ALQVMKLGNPEIARRLLLRG 60
+ P G+ L AR L SL + Q+ + AL + G E + L+ G
Sbjct: 391 SSPPGSTLGQGVAR-----LFSLFGCQEEDSVQDAVMPSLALALAHAGELEALQALMELG 445
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
++ LKD G ++H AAR G + LL DVN D +G PL LA + H +
Sbjct: 446 SDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIR 505
Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGA 164
L K A + ++ K D +L RL R ++ +QA G GA
Sbjct: 506 LLRKAGAC-LSPQDLK-DAGTELCRLASRADMEG-LQAWGQAGA 546
Score = 29.2 bits (64), Expect = 0.96, Method: Composition-based stats.
Identities = 17/56 (30%), Positives = 25/56 (44%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61
G EL A+R D+E L + Q ++ GR+AL V + + LL A
Sbjct: 523 GTELCRLASRADMEGLQAWGQAGADLQQPGYDGRSALCVAEAAGNQEVLALLRNLA 578
>1D9S-A nrPDB
Length = 136
Score = 117 bits (293), Expect = 3e-27, Method: Composition-based stats.
Identities = 50/123 (40%), Positives = 71/123 (57%), Gaps = 1/123 (0%)
Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60
+ LA+AAARG +E + LL+ + NA N FGR +QVM +G+ ++A LLL G
Sbjct: 8 LGGSSDAGLATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHG 67
Query: 61 ANPDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119
A P+ D +HDAAR GFLDTL L A +++ D G LP+ LA ++GH +
Sbjct: 68 AEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIA 127
Query: 120 EFL 122
+L
Sbjct: 128 RYL 130
Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats.
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 5/121 (4%)
Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103
G E R+LL GA+P+ +R G I G + LL A+ N D
Sbjct: 19 AAARGQVETVRQLLEAGADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAEPNCADPAT 77
Query: 104 NL-PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
P+H AA+EG L + L + A + + G DLA G ++ + + A
Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGAR-LDVCDAWGRLPVDLAEEQGHRDIARYL--HAAT 134
Query: 163 G 163
G
Sbjct: 135 G 135
>5D68-A nrPDB
Length = 486
Score = 111 bits (279), Expect = 1e-25, Method: Composition-based stats.
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 41 ALQ-VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNI 98
L G+ E+ RLL + + D +A IH A G ++ + LLE + N+
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 99 EDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLA---RLYGRNEVVSL 155
+ + + PLH AA GH +V+ L+ H ++ + +G + ++ + E L
Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 160
Query: 156 MQAN 159
++
Sbjct: 161 LKEA 164
Score = 83.9 bits (206), Expect = 3e-17, Method: Composition-based stats.
Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRG-ANPDL 65
L +A GD E L+ LL +VN + + G E R LL +G NP+L
Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPL 107
+ + +H AA G + +Q LL + D +I D +G PL
Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 143
Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats.
Identities = 13/55 (23%), Positives = 22/55 (40%), Gaps = 1/55 (1%)
Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
PLH +A EG ++ L+ +V + A YG+ E ++ G
Sbjct: 41 PLHRSACEGDSELLSRLLSE-RFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG 94
Score = 35.7 bits (81), Expect = 0.009, Method: Composition-based stats.
Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
Query: 7 NELASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMKL---GNPEIARRLLLRGAN 62
+ L AA G E + LL + + + GR+ L + + N E A +LL N
Sbjct: 107 SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAIN 166
>3EHQ-A nrPDB
Length = 222
Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats.
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 5/130 (3%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61
AE N L AA RG+L L L N V VN + G TAL G + +L
Sbjct: 70 AESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQP 129
Query: 62 NP--DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119
N + +++ G +H AA G+ D +Q LL A ++ + E L +A +
Sbjct: 130 NIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMAT---NAACA 186
Query: 120 EFLVKHTASN 129
L K ++
Sbjct: 187 SLLKKKQGTD 196
Score = 105 bits (263), Expect = 8e-24, Method: Composition-based stats.
Identities = 30/89 (33%), Positives = 44/89 (49%)
Query: 73 VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132
+H+AA+ G L L+ L+ + VN D G+ L+ A GH +VE L +
Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQ 135
Query: 133 RNHKGDTACDLARLYGRNEVVSLMQANGA 161
+N GDTA A G ++V L+ A GA
Sbjct: 136 QNKLGDTALHAAAWKGYADIVQLLLAKGA 164
>5UQE-A nrPDB
Length = 520
Score = 98.1 bits (243), Expect = 2e-21, Method: Composition-based stats.
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++
Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483
Query: 137 GDTACDLARLYGRNEVVSLMQA 158
+T D A +G ++V ++Q
Sbjct: 484 NNTPMDEALHFGHHDVFKILQE 505
Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats.
Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLE-FQADVNIED 100
L G+ RR L + + +D +H AA G ++ ++ LLE + + +D
Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 481
Query: 101 NEGNLPLHLAAKEGHLRVVEFL 122
N P+ A GH V + L
Sbjct: 482 RWNNTPMDEALHFGHHDVFKIL 503
Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats.
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLK 66
L AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP K
Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92
DR + +A G D + L E+
Sbjct: 481 DRWNNTPMDEALHFGHHDVFKILQEY 506
Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats.
Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 1/53 (1%)
Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
L AA G + + +A ++ R++ TA +A G EVV +
Sbjct: 421 LLFAAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 472
>3ZKJ-A nrPDB
Length = 261
Score = 97.7 bits (242), Expect = 2e-21, Method: Composition-based stats.
Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 3/156 (1%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65
+ + AA G L +L+ VN + L L G+ + LL GA +
Sbjct: 5 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 64
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+ +A +G D + LL+ A V +++ P+H AA+ GH+ V L+ +
Sbjct: 65 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAY 123
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
+ +H G T LA + V + +GA
Sbjct: 124 GGNIDHKISHLG-TPLYLACENQQRACVKKLLESGA 158
Score = 93.9 bits (232), Expect = 3e-20, Method: Composition-based stats.
Identities = 35/156 (22%), Positives = 66/156 (42%), Gaps = 4/156 (2%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDL 65
+ L A G L + LL++ VN T L G+ + LL GA+
Sbjct: 38 SPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP 97
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+ + IH+AAR G ++ + +L+ + +++ + + PL+LA + V+ L++
Sbjct: 98 ESDL-ASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLES 156
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161
A +V + D+ E+ L+ GA
Sbjct: 157 GA-DVN-QGKGQDSPLHAVARTASEELACLLMDFGA 190
Score = 89.2 bits (220), Expect = 8e-19, Method: Composition-based stats.
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 3/123 (2%)
Query: 39 RTALQ-VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN 97
+ + G+ R L+ +G ++ + +H+A G L ++ LL+ A VN
Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVN 63
Query: 98 IEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157
+ + PL A G V L++H AS + + A G E V+ +
Sbjct: 64 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA--SPIHEAARRGHVECVNSLI 121
Query: 158 ANG 160
A G
Sbjct: 122 AYG 124
Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats.
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128
+ ++ +H+AA G +L+ L+ VNI + PLH A GHL V+ L+KH A
Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQ 61
Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
V T A + G + V+L+ +GA
Sbjct: 62 -VNGVTADWHTPLFNACVSGSWDCVNLLLQHGAS 94
Score = 27.2 bits (59), Expect = 3.5, Method: Composition-based stats.
Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65
+ L + A E L+ + A+N G+ ++++ +P +A+ L R P L
Sbjct: 167 DSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESP-LAQLFLEREGPPSL 225
Query: 66 K 66
Sbjct: 226 M 226
>3UI2-A nrPDB
Length = 244
Score = 95.8 bits (237), Expect = 7e-21, Method: Composition-based stats.
Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62
PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+
Sbjct: 48 PW----WTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102
Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
D +D R G +H AA + ++ L+E AD+ +ED G L LA
Sbjct: 103 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151
Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats.
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 2/107 (1%)
Query: 40 TALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
T E A LL + D D G + A G ++ L E AD++
Sbjct: 47 TPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHR 106
Query: 100 DNE-GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLAR 145
D G LH+AA VVE LV+ A ++ + +G TA +LAR
Sbjct: 107 DMRGGLTALHMAAGYVRPEVVEALVELGA-DIEVEDERGLTALELAR 152
Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats.
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131
AAR L LLE + DV+ D G L A G + V L + A ++
Sbjct: 47 TPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGA-DLD 104
Query: 132 HRNHKG-DTACDLARLYGRNEVVSLMQANGA 161
HR+ +G TA +A Y R EVV + GA
Sbjct: 105 HRDMRGGLTALHMAAGYVRPEVVEALVELGA 135
Score = 30.7 bits (68), Expect = 0.32, Method: Composition-based stats.
Identities = 9/38 (23%), Positives = 20/38 (52%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK 46
L AA E + +L++ ++ ++ G TAL++ +
Sbjct: 115 LHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAR 152
>3DEO-A nrPDB
Length = 183
Score = 95.0 bits (235), Expect = 2e-20, Method: Composition-based stats.
Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62
PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+
Sbjct: 47 PW----WTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101
Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
D +D R G +H AA + ++ L+E AD+ +ED G L LA
Sbjct: 102 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150
Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats.
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 2/107 (1%)
Query: 40 TALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
T E A LL + D D G + A G ++ L E AD++
Sbjct: 46 TPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHR 105
Query: 100 DNE-GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLAR 145
D G LH+AA VVE LV+ A ++ + +G TA +LAR
Sbjct: 106 DMRGGLTALHMAAGYVRPEVVEALVELGA-DIEVEDERGLTALELAR 151
Score = 57.7 bits (138), Expect = 2e-09, Method: Composition-based stats.
Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131
AAR L LLE + DV+ D G L A G + V L + A ++
Sbjct: 46 TPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGA-DLD 103
Query: 132 HRNHKG-DTACDLARLYGRNEVVSLMQANGA 161
HR+ +G TA +A Y R EVV + GA
Sbjct: 104 HRDMRGGLTALHMAAGYVRPEVVEALVELGA 134
Score = 30.3 bits (67), Expect = 0.38, Method: Composition-based stats.
Identities = 9/38 (23%), Positives = 20/38 (52%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK 46
L AA E + +L++ ++ ++ G TAL++ +
Sbjct: 114 LHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAR 151
>5U0K-A nrPDB
Length = 141
Score = 93.5 bits (231), Expect = 4e-20, Method: Composition-based stats.
Identities = 26/81 (32%), Positives = 42/81 (51%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
AA +G + L+ D+ +D + LH+AA EGH+ VV+FL++ N ++
Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRW 91
Query: 137 GDTACDLARLYGRNEVVSLMQ 157
G+ D A + EVV L+Q
Sbjct: 92 GNIPLDDAVQFNHLEVVKLLQ 112
Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats.
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLE-FQADVNIED 100
L G+ RR L + + KD +H AA G ++ ++ L+E + + +D
Sbjct: 30 LFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKD 89
Query: 101 NEGNLPLHLAAKEGHLRVVEFL 122
GN+PL A + HL VV+ L
Sbjct: 90 RWGNIPLDDAVQFNHLEVVKLL 111
Score = 60.7 bits (146), Expect = 3e-10, Method: Composition-based stats.
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLK 66
L AA GD+ L + +++ ++ RTAL V G+ E+ + L+ NP K
Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92
DR G + DA + L+ ++ L ++
Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDY 114
>5U0J-A nrPDB
Length = 140
Score = 92.3 bits (228), Expect = 8e-20, Method: Composition-based stats.
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136
AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++
Sbjct: 31 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 90
Query: 137 GDTACDLARLYGRNEVVSLMQA 158
+T D A +G ++V ++Q
Sbjct: 91 NNTPMDEALHFGHHDVFKILQE 112
Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats.
Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLE-FQADVNIED 100
L G+ RR L + + +D +H AA G ++ ++ LLE + + +D
Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 88
Query: 101 NEGNLPLHLAAKEGHLRVVEFL 122
N P+ A GH V + L
Sbjct: 89 RWNNTPMDEALHFGHHDVFKIL 110
Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats.
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLK 66
L AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP K
Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92
DR + +A G D + L E+
Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEY 113
Score = 33.8 bits (76), Expect = 0.035, Method: Composition-based stats.
Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 1/53 (1%)
Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
L AA G + + +A ++ R++ TA +A G EVV +
Sbjct: 28 LLFAAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 79
>2KXP-C nrPDB
Length = 118
Score = 88.1 bits (217), Expect = 2e-18, Method: Composition-based stats.
Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 1/103 (0%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPD 64
E A GDL+++ + +VN GR L G EI LLL+GA+ +
Sbjct: 3 DKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADIN 62
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107
D+ + A G + ++ LL AD ++ +G L
Sbjct: 63 APDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105
Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats.
Identities = 30/116 (25%), Positives = 52/116 (44%), Gaps = 4/116 (3%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101
+ +K G+ + + + +G + + G +H AA G L+ L+ LL AD+N D
Sbjct: 7 MWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDK 66
Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157
PL A EGH+ V+ L+ A + + G TA + + +L+Q
Sbjct: 67 HHITPLLSAVYEGHVSCVKLLLSKGA-DKTVKGPDGLTALEAT---DNQAIKALLQ 118
Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats.
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%)
Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133
A + G LD ++ + DVN G PLH AA G L ++EFL+ A ++
Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGA-DINAP 64
Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGA 161
+ T A G V L+ + GA
Sbjct: 65 DKHHITPLLSAVYEGHVSCVKLLLSKGA 92
Score = 30.7 bits (68), Expect = 0.36, Method: Composition-based stats.
Identities = 12/51 (23%), Positives = 20/51 (39%), Gaps = 3/51 (5%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLL 58
L SA G + + LL + + G TAL+ + + + LL
Sbjct: 71 PLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEAT---DNQAIKALLQ 118
>6E2G-A nrPDB
Length = 727
Score = 84.2 bits (207), Expect = 2e-17, Method: Composition-based stats.
Identities = 38/177 (21%), Positives = 67/177 (37%), Gaps = 25/177 (14%)
Query: 5 WGNELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGAN 62
W + L AA +++ L LL+ V+ + G TAL + N E A L+
Sbjct: 45 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 104
Query: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGN 104
+ T G +H A ++ ++ LL A V+ G
Sbjct: 105 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 164
Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN----EVVSLMQ 157
PL AA G +V L++H A ++ ++ G+T + L ++ +L+
Sbjct: 165 HPLSFAACVGSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
Score = 69.6 bits (169), Expect = 5e-13, Method: Composition-based stats.
Identities = 32/141 (22%), Positives = 51/141 (36%), Gaps = 19/141 (13%)
Query: 40 TALQVMKLGN--PEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-- 95
+ L + N + + L G K G +H AA L+ L+E +
Sbjct: 47 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 96 ---VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA--------SNVGHRNHK----GDTA 140
+ E EG LH+A ++ +V L+ A S +R H G+
Sbjct: 107 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 166
Query: 141 CDLARLYGRNEVVSLMQANGA 161
A G E+V L+ +GA
Sbjct: 167 LSFAACVGSEEIVRLLIEHGA 187
Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 34/146 (23%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54
L A ++ + +LL +V+A+ +G L +G+ EI R
Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAARAGFLDTLQTLLEFQADVNIE------ 99
L+ GA+ +D G V+H A + L LL + +++
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL-----LLSYDGGDHLKSLELVP 235
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKH 125
+N+G P LA EG++ + + L++
Sbjct: 236 NNQGLTPFKLAGVEGNIVMFQHLMQK 261
>3LJN-A nrPDB
Length = 364
Score = 80.0 bits (196), Expect = 5e-16, Method: Composition-based stats.
Identities = 40/174 (22%), Positives = 67/174 (38%), Gaps = 27/174 (15%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDL 65
++ AA +G +++ L++ V+ QN FG TAL + G + A+ L G
Sbjct: 22 EKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG-EVHS 80
Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQAD--------VNIEDN-------------EGN 104
G IH A A D + L+E + +N D +G
Sbjct: 81 LWH-GQKPIHLAVMANKTDLVVALVEGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQ 139
Query: 105 LPLHLAAKEG--HLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
LH G +L +++ LV+ AS ++ +T A + E + LM
Sbjct: 140 TALHWCVGLGPEYLEMIKILVQLGASPT-AKDKADETPLMRAMEFRNREALDLM 192
Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats.
Identities = 32/141 (22%), Positives = 54/141 (38%), Gaps = 24/141 (17%)
Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103
+ G + RRL+ G +P +++R G +H A + G +DT + L +V+ G
Sbjct: 27 AARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG-EVHSL-WHG 84
Query: 104 NLPLHLAAKEGHLRVVEFLV-------KHTASNVGHRNH-------------KGDTACDL 143
P+HLA +V LV + S + + KG TA
Sbjct: 85 QKPIHLAVMANKTDLVVALVEGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHW 144
Query: 144 ARLYG--RNEVVSLMQANGAG 162
G E++ ++ GA
Sbjct: 145 CVGLGPEYLEMIKILVQLGAS 165
Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats.
Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126
D IH AAR G D ++ L+E I++ G LHLA K G + ++L
Sbjct: 17 DDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG 76
Query: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158
+ G LA + + ++V +
Sbjct: 77 EVHSLW---HGQKPIHLAVMANKTDLVVALVE 105
Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats.
Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 30/186 (16%)
Query: 9 LASAAARG--DLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGAN--- 62
L G LE + L+Q + A++ T L + M+ N E ++ +
Sbjct: 142 LHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSS 201
Query: 63 --PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120
D ++ G + +H A + D +E DVN+EDNE +PL+L+ + + + +
Sbjct: 202 LRLDYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTK 261
Query: 121 FLVKHTASNVGHRN--HKGDTAC----------DLARLYGRNEVVSLMQAN--------- 159
L++ T + H G T A + EV+ L+Q
Sbjct: 262 ELLQKTDVFLIQACPYHNGTTVLPDRVVWLDFVPAAADPSKQEVLQLLQEKLDEVVRSLN 321
Query: 160 -GAGGA 164
GAGGA
Sbjct: 322 TGAGGA 327
>6DMR-A nrPDB
Length = 730
Score = 76.1 bits (186), Expect = 6e-15, Method: Composition-based stats.
Identities = 42/176 (23%), Positives = 66/176 (37%), Gaps = 25/176 (14%)
Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
+ L AA DL L LL N + + G TAL V L + A LL+ A
Sbjct: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
Query: 65 LKDRT------GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGNL 105
K+ G +H A L+ ++ LL A V+ G
Sbjct: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165
Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN----EVVSLMQ 157
PL AA G +V L++H A ++ ++ G+T + L ++ +L+
Sbjct: 166 PLSFAACVGSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
Score = 60.4 bits (145), Expect = 3e-10, Method: Composition-based stats.
Identities = 30/151 (19%), Positives = 56/151 (37%), Gaps = 43/151 (28%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54
L A +L + +LL +V+A+ +G L +G+ EI R
Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180
Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAAR-----------AGFLDTLQTLLEFQA 94
L+ GA+ +D G V+H A + + L +L+
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLEL------ 234
Query: 95 DVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
+ +++G P LA EG+ + + L++
Sbjct: 235 ---VPNHQGLTPFKLAGVEGNTVMFQHLMQK 262
Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats.
Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 29/182 (15%)
Query: 4 PWGN--ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61
PW +L + G+ + ++ VN+ Q + L N ++LL
Sbjct: 11 PWAQLQKLLISWPVGEQDWEQY--RDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQ 68
Query: 62 NPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------NEGNLPLHLAAK 112
+ D + R G +H AA L+ L+E A + G LH+A
Sbjct: 69 SCDFQQRGAVGETALHVAALYDNLEAATLLME--AAPELAKEPALCEPFVGQTALHIAVM 126
Query: 113 EGHLRVVEFLVKHTASNVGHRNH-------------KGDTACDLARLYGRNEVVSLMQAN 159
+L +V L+ AS V R G+ A G E+V L+ +
Sbjct: 127 NQNLNLVRALLARGAS-VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH 185
Query: 160 GA 161
GA
Sbjct: 186 GA 187
Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats.
Identities = 22/97 (22%), Positives = 34/97 (35%), Gaps = 5/97 (5%)
Query: 71 FAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH---- 125
+ + AA+ L L+ LL D G LH+AA +L L++
Sbjct: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105
Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
G TA +A + +V + A GA
Sbjct: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142
>3T9K-A nrPDB
Length = 390
Score = 76.1 bits (186), Expect = 7e-15, Method: Composition-based stats.
Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 3/106 (2%)
Query: 57 LLRGANPDLKD--RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEG 114
L GA+ + + + + A A L + LL+ A+VN D+ G PLH A G
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 115 HLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
H + +K A ++G R+ +G +A ++V+L++
Sbjct: 280 HTGLACLFLKRGA-DLGARDSEGRDPLTIAMETANADIVTLLRLAK 324
Score = 74.2 bits (181), Expect = 3e-14, Method: Composition-based stats.
Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 4/118 (3%)
Query: 25 LQNNVNVNAQNGF--GRTAL-QVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAG 81
L + +VN NG T L Q + LL GAN + D G +H A G
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279
Query: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL-VKHTASNVGHRNHKGD 138
L+ AD+ D+EG PL +A + + +V L + + GD
Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGD 337
Score = 56.5 bits (135), Expect = 5e-09, Method: Composition-based stats.
Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 1/88 (1%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66
L A A L LLQN NVN + GR L LG+ +A L RGA+ +
Sbjct: 238 PLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGAR 297
Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQA 94
D G + A D + L +
Sbjct: 298 DSEGRDPLTIAMETANADIVTLLRLAKM 325
Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats.
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 3/74 (4%)
Query: 90 LEFQADVNIED--NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLY 147
L ADVN + + PL A L EFL+++ A NV + G A +
Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGA-NVNQADSAGRGPLHHATIL 278
Query: 148 GRNEVVSLMQANGA 161
G + L GA
Sbjct: 279 GHTGLACLFLKRGA 292
>2RFA-A nrPDB
Length = 232
Score = 75.8 bits (185), Expect = 9e-15, Method: Composition-based stats.
Identities = 38/167 (22%), Positives = 63/167 (37%), Gaps = 21/167 (12%)
Query: 5 WGNELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGAN 62
W + L AA D++ L+ LL+ V+ + G TAL + N E A L+
Sbjct: 3 WESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 62
Query: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGN 104
+ T G +H A ++ ++ LL A V+ G
Sbjct: 63 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 122
Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE 151
PL AA G +V L++H A ++ ++ G+T + L
Sbjct: 123 HPLSFAACVGSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKT 168
Score = 62.7 bits (151), Expect = 7e-11, Method: Composition-based stats.
Identities = 32/141 (22%), Positives = 51/141 (36%), Gaps = 19/141 (13%)
Query: 40 TALQVMKLGNPEIA--RRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-- 95
+ L + N A + L G + G +H AA L+ L+E +
Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64
Query: 96 ---VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA--------SNVGHRNHK----GDTA 140
+ E EG LH+A ++ +V L+ A S +R H G+
Sbjct: 65 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 124
Query: 141 CDLARLYGRNEVVSLMQANGA 161
A G E+V L+ +GA
Sbjct: 125 LSFAACVGSEEIVRLLIEHGA 145
Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats.
Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 5/96 (5%)
Query: 72 AVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
+ + AA+ + L LL+F +V+ G LH+AA +L L++ V
Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64
Query: 131 GHRNH----KGDTACDLARLYGRNEVVSLMQANGAG 162
+G TA +A + +V + A GA
Sbjct: 65 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 100
Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 34/146 (23%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54
L A ++ + +LL +V+A+ +G L +G+ EI R
Sbjct: 79 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 138
Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAARAGFLDTLQTLLEFQADVNIE------ 99
L+ GA+ +D G V+H A + L LL + +++
Sbjct: 139 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL-----LLSYDGGDHLKSLELVP 193
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKH 125
+N+G P LA EG++ + + L++
Sbjct: 194 NNQGLTPFKLAGVEGNIVMFQHLMQK 219
>6BOA-A nrPDB
Length = 742
Score = 74.6 bits (182), Expect = 2e-14, Method: Composition-based stats.
Identities = 38/177 (21%), Positives = 67/177 (37%), Gaps = 25/177 (14%)
Query: 5 WGNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGAN 62
W + L AA D++ L LL+ V+ + G TAL + N E A L+
Sbjct: 45 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 104
Query: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGN 104
+ T G +H A ++ ++ LL +A V+ G
Sbjct: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164
Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN----EVVSLMQ 157
PL AA +V L++H A ++ ++ G+T + L ++ +L+
Sbjct: 165 HPLSFAACVNSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220
Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats.
Identities = 29/141 (20%), Positives = 47/141 (33%), Gaps = 19/141 (13%)
Query: 40 TALQVMKLGNPEIA--RRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-- 95
+ L + N A + L + G +H AA L+ L+E +
Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 96 ---VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN----------VGHRNH--KGDTA 140
+ E EG LH+A ++ +V L+ AS N G+
Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166
Query: 141 CDLARLYGRNEVVSLMQANGA 161
A E+V L+ +GA
Sbjct: 167 LSFAACVNSEEIVRLLIEHGA 187
Score = 60.0 bits (144), Expect = 5e-10, Method: Composition-based stats.
Identities = 21/96 (21%), Positives = 37/96 (38%), Gaps = 5/96 (5%)
Query: 72 AVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
+ + AA+ + L LL++ V+ G LH+AA +L L++ V
Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106
Query: 131 GHRNH----KGDTACDLARLYGRNEVVSLMQANGAG 162
+G TA +A + +V + A A
Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 142
Score = 55.0 bits (131), Expect = 1e-08, Method: Composition-based stats.
Identities = 29/146 (19%), Positives = 54/146 (36%), Gaps = 33/146 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54
L A ++ + +LL +V+A+ FG L + + EI R
Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180
Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAARAGFLDTLQTLLEFQADVN------IE 99
L+ GA+ +D G V+H A + L L + + +
Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL----LLSYDRHGDHLQPLDLVP 236
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKH 125
+++G P LA EG+ + + L++
Sbjct: 237 NHQGLTPFKLAGVEGNTVMFQHLMQK 262
>4BSZ-B nrPDB
Length = 202
Score = 72.7 bits (177), Expect = 8e-14, Method: Composition-based stats.
Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 15/130 (11%)
Query: 45 MKLGNPEIARRLLLRGANPDL-----KDRTGFAVIHDAARAGFLDTLQTLLE-------- 91
+ G+ + + + +P+L + + +H AA G ++T++ +LE
Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81
Query: 92 --FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGR 149
+A VN + GN LH A+ G L VV+ L ++ RN G A A G+
Sbjct: 82 EDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGK 141
Query: 150 NEVVSLMQAN 159
EV +
Sbjct: 142 EEVETYFLKK 151
Score = 54.2 bits (129), Expect = 2e-08, Method: Composition-based stats.
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 12/103 (11%)
Query: 2 AEPWGNELASAAARGDLEQLTSLLQ--NNVN--------VNAQNGFGRTALQVMKL-GNP 50
+E L AAA G +E + +L+ + N VN N G TAL L G
Sbjct: 49 SESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKL 108
Query: 51 EIARRLL-LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF 92
++ + L A+P ++++ G I +A +G + L+
Sbjct: 109 DVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 151
>3LVQ-E nrPDB
Length = 497
Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 63 PDLKDRTGFAVIHDA---ARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119
PD + +H A A L + +++ ++ + +GN LH AA +
Sbjct: 165 PDAQAPEELV-LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 223
Query: 120 EFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
+ L+K + VG N G+TA D+AR E L++ AG
Sbjct: 224 KLLLK-GRALVGTVNEAGETALDIARKKHHKECEELLEQAQAG 265
Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats.
Identities = 29/140 (20%), Positives = 46/140 (32%), Gaps = 16/140 (11%)
Query: 4 PWGNELASAAARGDLEQLTSLLQNNVN---------VNAQNGFGRTALQVMK----LGNP 50
P L +A DL + N + A L + +
Sbjct: 131 PEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL---VLHLAVKVANQASL 187
Query: 51 EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
+ ++ G + D K G +H AA D L+ LL+ +A V + G L +A
Sbjct: 188 PLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIA 247
Query: 111 AKEGHLRVVEFLVKHTASNV 130
K+ H E L + A
Sbjct: 248 RKKHHKECEELLEQAQAGTF 267
>6DVZ-A nrPDB
Length = 791
Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats.
Identities = 36/176 (20%), Positives = 61/176 (34%), Gaps = 45/176 (25%)
Query: 12 AAARGDLEQLTSLLQNNVNV-------NAQN---------GFGRTALQVMKLG----NPE 51
A + G +E+L LLQ+ ++ + + G+T L L E
Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 185
Query: 52 IARRLLLRGANPDLKDR-----------TGFAVIHDAARAGFLDTLQTLLEFQADVNIED 100
I R LL D+ DR G ++ A D L+ ADVN
Sbjct: 186 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHA 245
Query: 101 N--------------EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142
G PL LAA +V+ L+++ +++ ++ +G+
Sbjct: 246 KGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 301
Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats.
Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 30/140 (21%)
Query: 14 ARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIARRLLL 58
+GD+ + L+ +VNA FG T L + PEI + L+
Sbjct: 226 RQGDITAV--LIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME 283
Query: 59 R-GANPDLKDRTGFAVIH-DAARAGFLDTLQTLLEFQADV-----------NIEDNEGNL 105
+ +D G ++H A T ++ D+ + +N+G
Sbjct: 284 NEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLT 343
Query: 106 PLHLAAKEGHLRVVEFLVKH 125
PL LAAK G ++++++
Sbjct: 344 PLQLAAKMGKAEILKYILSR 363
>4N5Q-A nrPDB
Length = 257
Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats.
Identities = 36/181 (19%), Positives = 63/181 (34%), Gaps = 45/181 (24%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNV-------NAQN---------GFGRTALQVMKLG-- 48
+ +A + G +E+L LLQ+ ++ + + G+T L L
Sbjct: 5 KRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNIN 64
Query: 49 --NPEIARRLLLRGANPDLKDR-----------TGFAVIHDAARAGFLDTLQTLLEFQAD 95
EI R LL D+ DR G ++ A D L+ AD
Sbjct: 65 PNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGAD 124
Query: 96 VNIEDN--------------EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTAC 141
VN G PL LAA +V+ L+++ +++ ++ +G+
Sbjct: 125 VNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNIL 184
Query: 142 D 142
Sbjct: 185 H 185
Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats.
Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 30/140 (21%)
Query: 14 ARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIARRLLL 58
+GD+ + L+ +VNA FG T L + PEI + L+
Sbjct: 110 RQGDITAV--LIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME 167
Query: 59 R-GANPDLKDRTGFAVIH-DAARAGFLDTLQTLLEFQADV-----------NIEDNEGNL 105
+ +D G ++H A T ++ D+ + +N+G
Sbjct: 168 NEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLT 227
Query: 106 PLHLAAKEGHLRVVEFLVKH 125
PL LAAK G ++++++
Sbjct: 228 PLQLAAKMGKAEILKYILSR 247
>2B0O-E nrPDB
Length = 301
Score = 62.7 bits (151), Expect = 7e-11, Method: Composition-based stats.
Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 63 PDLKDRTGFAVIHDA---ARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119
PD + +H A A L + +++ ++ + +GN LH AA +
Sbjct: 184 PDAQAPEELV-LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 242
Query: 120 EFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
+ L+K + VG N G+TA D+AR E L++ AG
Sbjct: 243 KLLLK-GRALVGTVNEAGETALDIARKKHHKECEELLEQAQAG 284
Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats.
Identities = 29/140 (20%), Positives = 46/140 (32%), Gaps = 16/140 (11%)
Query: 4 PWGNELASAAARGDLEQLTSLLQNNVN---------VNAQNGFGRTALQVMK----LGNP 50
P L +A DL + N + A L + +
Sbjct: 150 PEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL---VLHLAVKVANQASL 206
Query: 51 EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110
+ ++ G + D K G +H AA D L+ LL+ +A V + G L +A
Sbjct: 207 PLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIA 266
Query: 111 AKEGHLRVVEFLVKHTASNV 130
K+ H E L + A
Sbjct: 267 RKKHHKECEELLEQAQAGTF 286
>1DCQ-A nrPDB
Length = 278
Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats.
Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 12/153 (7%)
Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFA 72
A + + L V ++ FG LQ G + L G PD
Sbjct: 120 ARKKHADTAAKLHSLCEAVKTRDIFG--LLQAYADGVDLTEKIPLANGHEPD------ET 171
Query: 73 VIHDAARAGF---LDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129
+H A R+ L + L++ +++ + +G+ LH + ++ L+ ++
Sbjct: 172 ALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLL-RGKAS 230
Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162
+ N G+T D+A+ L+ +G
Sbjct: 231 IEIANESGETPLDIAKRLKHEHCEELLTQALSG 263
Score = 59.6 bits (143), Expect = 7e-10, Method: Composition-based stats.
Identities = 27/128 (21%), Positives = 42/128 (32%), Gaps = 10/128 (7%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLG----NPEIARRLLLRGANPD 64
L A A G L N + TAL + + I L+ N D
Sbjct: 146 LLQAYADGVDLTEKIPLANGHEPDE------TALHLAVRSVDRTSLHIVDFLVQNSGNLD 199
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124
+ G +H + L+ LL +A + I + G PL +A + H E L +
Sbjct: 200 KQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQ 259
Query: 125 HTASNVGH 132
+
Sbjct: 260 ALSGRFNS 267
Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats.
Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 15/123 (12%)
Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTL-LEFQADVNIEDNE 102
+ + + A +L +D G A A +D + + L + +
Sbjct: 119 YARKKHADTAAKLHSLCEAVKTRDIFGL----LQAYADGVDLTEKIPLANGHEPDE---- 170
Query: 103 GNLPLHLAAK---EGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159
LHLA + L +V+FLV++ + N+ + KG TA L E + L+
Sbjct: 171 --TALHLAVRSVDRTSLHIVDFLVQN-SGNLDKQTGKGSTALHYCCLTDNAECLKLLLRG 227
Query: 160 GAG 162
A
Sbjct: 228 KAS 230
>6CUD-A nrPDB
Length = 806
Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 52/146 (35%), Gaps = 31/146 (21%)
Query: 42 LQVMKLGNPEIARRLLLRG--ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
L + GN + R++L N + D G + A L+ + LL+ + I
Sbjct: 32 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 91
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTA------------------SNVGHRNHKGD--- 138
D L LA +G++R+VE ++ H + + G
Sbjct: 92 D-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFS 146
Query: 139 ---TACDLARLYGRNEVVSLMQANGA 161
T LA + EVV ++ GA
Sbjct: 147 PDITPIILAAHCQKYEVVHMLLMKGA 172
Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats.
Identities = 32/149 (21%), Positives = 54/149 (36%), Gaps = 31/149 (20%)
Query: 7 NELASAAARGDLEQLTSLLQNN--VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
AA G++ + +L+ + +NVN + G+ ALQ+ LLL+ N
Sbjct: 29 ERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 88
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEF---QADVNIE----------------DNEGN- 104
R G A++ A G++ ++ +L A + D +G
Sbjct: 89 ---RIGDALL-LAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTR 144
Query: 105 -----LPLHLAAKEGHLRVVEFLVKHTAS 128
P+ LAA VV L+ A
Sbjct: 145 FSPDITPIILAAHCQKYEVVHMLLMKGAR 173
>5IRX-A nrPDB
Length = 636
Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats.
Identities = 36/175 (20%), Positives = 63/175 (36%), Gaps = 39/175 (22%)
Query: 7 NELASAAARGDLEQLTSLL-------QNNVNVNAQN-GFGRTALQVMKL----GNPEIAR 54
+ A A+ + ++L SLL + + ++ G+T L L G +
Sbjct: 10 RSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTIA 69
Query: 55 RLLLRGANPDLKDRT-----------GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100
LL D + G +H A + + L+E ADV
Sbjct: 70 LLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGD 129
Query: 101 -----------NEGNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142
G LPL LAA L +V+FL++++ +++ R+ G+T
Sbjct: 130 FFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 184
Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats.
Identities = 35/168 (20%), Positives = 62/168 (36%), Gaps = 35/168 (20%)
Query: 25 LQNNVNVNAQNGF--GRTALQVM-KLGNPEIARRLLLRGANPDLKDRT------------ 69
L+ VN + + + G+TAL + + N + L+ GA+
Sbjct: 81 LKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGF 140
Query: 70 --GFAVIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAKE-----GHLRVV 119
G + AA L ++ LL+ AD++ D+ GN LH + + + V
Sbjct: 141 YFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFV 200
Query: 120 -----EFLVKHTASNVGHR-----NHKGDTACDLARLYGRNEVVSLMQ 157
E L+ + + N KG T LA G+ V++ +
Sbjct: 201 TSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYIL 248
Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats.
Identities = 31/151 (20%), Positives = 56/151 (37%), Gaps = 34/151 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53
L A R ++ +T L++N +V A FG L + I
Sbjct: 100 LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIV 159
Query: 54 RRLLL---RGANPDLKDRTGFAVIH--DAARAGFLDTLQT-------LLEFQADVN---- 97
+ LL + A+ +D G V+H +D + +L A ++
Sbjct: 160 KFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLK 219
Query: 98 ---IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I + +G PL LAA G + V+ ++++
Sbjct: 220 LEEITNRKGLTPLALAASSGKIGVLAYILQR 250
Score = 32.6 bits (73), Expect = 0.081, Method: Composition-based stats.
Identities = 17/81 (20%), Positives = 25/81 (30%), Gaps = 14/81 (17%)
Query: 95 DVNIED-NEGNLPLHLA---AKEGHLRVVEFLVKHTASNVGHRNH----------KGDTA 140
D +D G L A G + L+ + KG TA
Sbjct: 40 DSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTA 99
Query: 141 CDLARLYGRNEVVSLMQANGA 161
+A +V+L+ NGA
Sbjct: 100 LHIAIERRNMTLVTLLVENGA 120
>6CV9-A nrPDB
Length = 842
Score = 60.0 bits (144), Expect = 5e-10, Method: Composition-based stats.
Identities = 30/146 (20%), Positives = 51/146 (34%), Gaps = 31/146 (21%)
Query: 42 LQVMKLGNPEIARRLLL--RGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
L + GN + R++L N + D G + A L+ + LL+ + +
Sbjct: 14 LDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTA------------------SNVGHRNHKGD--- 138
D L LA +G++R+VE ++ H A + + G
Sbjct: 74 D-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFS 128
Query: 139 ---TACDLARLYGRNEVVSLMQANGA 161
T LA E+V + GA
Sbjct: 129 HDVTPIILAAHCQEYEIVHTLLRKGA 154
Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats.
Identities = 32/150 (21%), Positives = 58/150 (38%), Gaps = 33/150 (22%)
Query: 7 NELASAAARGDLEQLTSLLQ--NNVNVNAQNGFGRTALQVMKLG-NPEIARRLLLRGANP 63
AA G++ + +L+ +++NVN + G+ ALQ+ + EI LL +
Sbjct: 11 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK---- 66
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQA-------------------DVNIEDNEGN 104
+ R G A++ A G++ ++ +L A D D +G
Sbjct: 67 ENLSRVGDALL-LAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 125
Query: 105 ------LPLHLAAKEGHLRVVEFLVKHTAS 128
P+ LAA +V L++ A
Sbjct: 126 RFSHDVTPIILAAHCQEYEIVHTLLRKGAR 155
>6DJS-A nrPDB
Length = 676
Score = 59.6 bits (143), Expect = 6e-10, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 52/146 (35%), Gaps = 31/146 (21%)
Query: 42 LQVMKLGNPEIARRLLLRG--ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
L + GN + R++L N + D G + A L+ + LL+ + I
Sbjct: 49 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 108
Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTA------------------SNVGHRNHKGD--- 138
D L LA +G++R+VE ++ H + + G
Sbjct: 109 D-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFS 163
Query: 139 ---TACDLARLYGRNEVVSLMQANGA 161
T LA + EVV ++ GA
Sbjct: 164 PDITPIILAAHCQKYEVVHMLLMKGA 189
Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats.
Identities = 32/149 (21%), Positives = 54/149 (36%), Gaps = 31/149 (20%)
Query: 7 NELASAAARGDLEQLTSLLQNN--VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64
AA G++ + +L+ + +NVN + G+ ALQ+ LLL+ N
Sbjct: 46 ERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 105
Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEF---QADVNIE----------------DNEGN- 104
R G A++ A G++ ++ +L A + D +G
Sbjct: 106 ---RIGDALL-LAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTR 161
Query: 105 -----LPLHLAAKEGHLRVVEFLVKHTAS 128
P+ LAA VV L+ A
Sbjct: 162 FSPDITPIILAAHCQKYEVVHMLLMKGAR 190
>6OO7-A nrPDB
Length = 786
Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats.
Identities = 34/150 (22%), Positives = 60/150 (40%), Gaps = 33/150 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNA----------QNG---FGRTALQVM-KLGNPEIAR 54
L A + L+ + L++N NV+A Q+ FG L + ++
Sbjct: 166 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 225
Query: 55 RLLL---RGANPDLKDRTGFAVIH------DAARAGFLDTLQT---LLEFQADVN----- 97
LL + A+ +D G V+H D + ++ LL+ A +
Sbjct: 226 YLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARLCPNVQL 285
Query: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I + EG PL LAAKEG + + + +++
Sbjct: 286 EGIPNLEGLTPLKLAAKEGKIEIFKHILQR 315
Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats.
Identities = 39/164 (23%), Positives = 60/164 (36%), Gaps = 35/164 (21%)
Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDL----------KDR---TGFA 72
VN + + G +AL + + + + L+ GAN +D G
Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210
Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121
+ AA D + LLE A + +D+ GN LH E VV
Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270
Query: 122 -LVKHTAS---NV---GHRNHKGDTACDLARLYGRNEVVS-LMQ 157
L++ A NV G N +G T LA G+ E+ ++Q
Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQ 314
Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats.
Identities = 38/174 (21%), Positives = 64/174 (36%), Gaps = 38/174 (21%)
Query: 7 NELASAAARGDLEQLTSLLQNN-------VNVNAQNGF-GRTALQVM----KLGNPEIAR 54
+ L + ARG+ E L LL+ + G G+T L + G +
Sbjct: 76 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 135
Query: 55 RLLL----RG-----ANPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100
LL G N D G + +H A L ++ L+E A+V+ +
Sbjct: 136 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 195
Query: 101 ----------NEGNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142
G LPL LAA VV +L+++ +++ ++ G+T
Sbjct: 196 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLH 249
Score = 33.4 bits (75), Expect = 0.047, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 40/109 (36%), Gaps = 21/109 (19%)
Query: 74 IHDAARAGFLDTLQTLLEF--QADVNIEDNE------GNLPLHLAA---KEGHLRVVEFL 122
+ + G + L LLE+ + + D+E G L A ++G ++ L
Sbjct: 78 LFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPL 137
Query: 123 VK------HTASNVGHRNHK----GDTACDLARLYGRNEVVSLMQANGA 161
++ + V + G +A +A + V L+ NGA
Sbjct: 138 LEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGA 186
>2NYJ-A nrPDB
Length = 273
Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats.
Identities = 36/175 (20%), Positives = 63/175 (36%), Gaps = 39/175 (22%)
Query: 7 NELASAAARGDLEQLTSLL-------QNNVNVNAQN-GFGRTALQVMKL----GNPEIAR 54
+ A A+ + ++L SLL + + ++ G+T L L G +
Sbjct: 15 RSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTIA 74
Query: 55 RLLLRGANPDLKDRT-----------GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100
LL D + G +H A + + L+E ADV
Sbjct: 75 LLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGD 134
Query: 101 -----------NEGNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142
G LPL LAA L +V+FL++++ +++ R+ G+T
Sbjct: 135 FFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 189
Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats.
Identities = 35/168 (20%), Positives = 62/168 (36%), Gaps = 35/168 (20%)
Query: 25 LQNNVNVNAQNGF--GRTALQVM-KLGNPEIARRLLLRGANPDLKDRT------------ 69
L+ VN + + + G+TAL + + N + L+ GA+
Sbjct: 86 LKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGF 145
Query: 70 --GFAVIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAKE-----GHLRVV 119
G + AA L ++ LL+ AD++ D+ GN LH + + + V
Sbjct: 146 YFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFV 205
Query: 120 -----EFLVKHTASNVGHR-----NHKGDTACDLARLYGRNEVVSLMQ 157
E L+ + + N KG T LA G+ V++ +
Sbjct: 206 TSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYIL 253
Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats.
Identities = 31/151 (20%), Positives = 56/151 (37%), Gaps = 34/151 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53
L A R ++ +T L++N +V A FG L + I
Sbjct: 105 LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIV 164
Query: 54 RRLLL---RGANPDLKDRTGFAVIH--DAARAGFLDTLQT-------LLEFQADVN---- 97
+ LL + A+ +D G V+H +D + +L A ++
Sbjct: 165 KFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLK 224
Query: 98 ---IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I + +G PL LAA G + V+ ++++
Sbjct: 225 LEEITNRKGLTPLALAASSGKIGVLAYILQR 255
Score = 31.8 bits (71), Expect = 0.15, Method: Composition-based stats.
Identities = 15/74 (20%), Positives = 22/74 (29%), Gaps = 13/74 (17%)
Query: 101 NEGNLPLHLA---AKEGHLRVVEFLVKHTASNVGHRNH----------KGDTACDLARLY 147
G L A G + L+ + KG TA +A
Sbjct: 52 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 111
Query: 148 GRNEVVSLMQANGA 161
+V+L+ NGA
Sbjct: 112 RNMTLVTLLVENGA 125
>5UIL-A nrPDB
Length = 405
Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats.
Identities = 23/124 (18%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65
E+ A D + + L++ + +N +G + + V GN E+ + L+ +GAN +
Sbjct: 280 KEILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANIND 339
Query: 66 KDRTGFAVIH----DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121
++ G V ++G L+ L++ D+ + D + K G+ ++++
Sbjct: 340 RNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQY 399
Query: 122 LVKH 125
++
Sbjct: 400 MMAF 403
Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats.
Identities = 21/121 (17%), Positives = 51/121 (42%), Gaps = 5/121 (4%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101
L+ K + + +L+ + K+ G++ + AA G ++ ++ L+ A++N +
Sbjct: 283 LEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANINDRNY 342
Query: 102 EGNL-PLHLA---AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157
+G ++ K G ++ L+ ++ ++K T D G ++ M
Sbjct: 343 KGTTVAMYFKDYMLKSGDYSGLKMLIDLG-LDLTLTDYKDYTVFDYLEKSGNKNLLQYMM 401
Query: 158 A 158
A
Sbjct: 402 A 402
Score = 31.5 bits (70), Expect = 0.17, Method: Composition-based stats.
Identities = 11/61 (18%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
+ + A K + + L+ S + +N G + +A +G E++ + + G
Sbjct: 276 KDNFKEILEACKYSDSKYIAKLI-RAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKG 334
Query: 161 A 161
A
Sbjct: 335 A 335
>5AN8-A nrPDB
Length = 613
Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats.
Identities = 33/150 (22%), Positives = 57/150 (38%), Gaps = 33/150 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNA----------QNG---FGRTALQVM-KLGNPEIAR 54
L A + L+ + L++N NV+A Q+ FG L + ++
Sbjct: 91 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 150
Query: 55 RLLLRG---ANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADVN----- 97
LL A+ +D G V+H ++ LL+ A +
Sbjct: 151 YLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLLQAGARLCPNVQL 210
Query: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I + EG PL LAAKEG + + + +++
Sbjct: 211 EGIPNLEGLTPLKLAAKEGKIEIFKHILQR 240
Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats.
Identities = 45/209 (21%), Positives = 74/209 (35%), Gaps = 47/209 (22%)
Query: 7 NELASAAARGDLEQLTSLLQNN-------VNVNAQNGF-GRTALQVM----KLGNPEIAR 54
+ L + ARG+ E L LL+ + G G+T L + G +
Sbjct: 1 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 60
Query: 55 RLLL----RG-----ANPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100
LL G N D G + +H A L ++ L+E A+V+ +
Sbjct: 61 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 120
Query: 101 ----------NEGNLPLHLAAKEGHLRVVEFLV--KHTASNVGHRNHKGDTACD-LARLY 147
G LPL LAA VV +L+ H A+++ ++ G+T L +
Sbjct: 121 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIA 180
Query: 148 GRN--------EVVSLMQANGAGGATNLQ 168
+ + + GA N+Q
Sbjct: 181 DNSPENSALVVRMYDGLLQAGARLCPNVQ 209
Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats.
Identities = 39/164 (23%), Positives = 60/164 (36%), Gaps = 35/164 (21%)
Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDL----------KDR---TGFA 72
VN + + G +AL + + + + L+ GAN +D G
Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135
Query: 73 VIHDAARAGFLDTLQTLLEF---QADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121
+ AA D + LLE A + +D+ GN LH E VV
Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195
Query: 122 -LVKHTAS---NV---GHRNHKGDTACDLARLYGRNEVVS-LMQ 157
L++ A NV G N +G T LA G+ E+ ++Q
Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQ 239
>6BO5-A nrPDB
Length = 695
Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats.
Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 35/164 (21%)
Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDLKDRT-------------GFA 72
VN + F G +AL + + + + L+ GA+ L+ G
Sbjct: 113 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 172
Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121
+ AA D + LLE A + D+ GN LH E V+
Sbjct: 173 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 232
Query: 122 -LVKHTASNV------GHRNHKGDTACDLARLYGRNEVVS-LMQ 157
L++ A NH+G T LA G+ E+ ++Q
Sbjct: 233 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 276
Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats.
Identities = 29/151 (19%), Positives = 53/151 (35%), Gaps = 35/151 (23%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVN-------AQNGFGRTALQ--------VMKLGNPEIA 53
L A + L+ + L++N +V+ Q G T ++
Sbjct: 128 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQG-TCFYFGELPLSLAACTKQWDVV 186
Query: 54 RRLLL---RGANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADV----- 96
LL + A+ + D G V+H + LL+ A +
Sbjct: 187 TYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 246
Query: 97 --NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I +++G PL LAAKEG + + +++
Sbjct: 247 LEEISNHQGLTPLKLAAKEGKIEIFRHILQR 277
Score = 31.8 bits (71), Expect = 0.13, Method: Composition-based stats.
Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 13/72 (18%)
Query: 103 GNLPLHLAA---KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGR 149
G L A ++G + L++ + V + G +A +A
Sbjct: 77 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRS 136
Query: 150 NEVVSLMQANGA 161
+ V L+ NGA
Sbjct: 137 LQCVKLLVENGA 148
>5HI9-A nrPDB
Length = 770
Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats.
Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 35/164 (21%)
Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDLKDRT-------------GFA 72
VN + F G +AL + + + + L+ GA+ L+ G
Sbjct: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212
Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121
+ AA D + LLE A + D+ GN LH E V+
Sbjct: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272
Query: 122 -LVKHTASNV------GHRNHKGDTACDLARLYGRNEVVS-LMQ 157
L++ A NH+G T LA G+ E+ ++Q
Sbjct: 273 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316
Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats.
Identities = 29/151 (19%), Positives = 53/151 (35%), Gaps = 35/151 (23%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVN-------AQNGFGRTALQ--------VMKLGNPEIA 53
L A + L+ + L++N +V+ Q G T ++
Sbjct: 168 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQG-TCFYFGELPLSLAACTKQWDVV 226
Query: 54 RRLLL---RGANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADV----- 96
LL + A+ + D G V+H + LL+ A +
Sbjct: 227 TYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 286
Query: 97 --NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I +++G PL LAAKEG + + +++
Sbjct: 287 LEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317
Score = 31.8 bits (71), Expect = 0.13, Method: Composition-based stats.
Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 13/72 (18%)
Query: 103 GNLPLHLAA---KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGR 149
G L A ++G + L++ + V + G +A +A
Sbjct: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRS 176
Query: 150 NEVVSLMQANGA 161
+ V L+ NGA
Sbjct: 177 LQCVKLLVENGA 188
>6G1K-A nrPDB
Length = 921
Score = 53.4 bits (127), Expect = 4e-08, Method: Composition-based stats.
Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 26/138 (18%)
Query: 10 ASAAARGDLEQLTSLLQNN-----VNVNAQNGFGRTALQVMKLG-NPEIARRLLLRGANP 63
SA +GD + L+ +N+N + GRTAL + N EI LL N
Sbjct: 37 LSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLS--FNV 94
Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQ------------ADVNIEDNEGN-LPLHLA 110
+ G A++H A R + ++ LL + D D + P+ LA
Sbjct: 95 YV----GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILA 149
Query: 111 AKEGHLRVVEFLVKHTAS 128
A + +++ LV+ S
Sbjct: 150 AHTNNYEIIKMLVQKGVS 167
Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats.
Identities = 26/139 (18%), Positives = 47/139 (33%), Gaps = 24/139 (17%)
Query: 39 RTALQVMKLGNPEIARRLLLRGA-----NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ 93
++ L ++ G+ + L N + D G + A L+ ++ LL F
Sbjct: 34 KSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFN 93
Query: 94 ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS-------NVGHRNHKGD-----TAC 141
V G+ LH A ++ + VE L+ H + D T
Sbjct: 94 VYV------GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPI 146
Query: 142 DLARLYGRNEVVSLMQANG 160
LA E++ ++ G
Sbjct: 147 ILAAHTNNYEIIKMLVQKG 165
>6C8G-A nrPDB
Length = 675
Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats.
Identities = 21/98 (21%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115
G +H A ++ L+E ADV+ + G LPL LAA
Sbjct: 103 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 162
Query: 116 LRVVEFLVK--HTASNVGHRNHKGDTACD-LARLYGRN 150
+V +L + H +++ ++ +G+T L +
Sbjct: 163 PDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNT 200
Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats.
Identities = 28/151 (18%), Positives = 51/151 (33%), Gaps = 33/151 (21%)
Query: 37 FGRTALQVMKLGNPE-IARRLLLRGANPDLK---------DRTGF-----AVIHDAARAG 81
G+TAL + + L+ +GA+ + D G+ + AA
Sbjct: 102 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 161
Query: 82 FLDTLQTLLEF---QADVNIEDNEGNLPLH--LAAKEGHLRVVEFLVKHTASNVGHR--- 133
D + L E +AD+ +D+ GN LH +A + +F+ K V
Sbjct: 162 QPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKL 221
Query: 134 ----------NHKGDTACDLARLYGRNEVVS 154
N+ + +A G+ +
Sbjct: 222 YPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQ 252
Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats.
Identities = 32/160 (20%), Positives = 57/160 (35%), Gaps = 34/160 (21%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53
L A R + L++ +V+AQ FG L + P+I
Sbjct: 107 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 166
Query: 54 RRLLLRG---ANPDLKDRTGFAVIH-DAARAGF-----------LDTLQT-LLEFQADVN 97
L A+ +D G V+H A A D L ++ D +
Sbjct: 167 HYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSS 226
Query: 98 IE---DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRN 134
+E +N+ PL +AAK G + + + +++ + R+
Sbjct: 227 LEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARH 266
Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats.
Identities = 15/74 (20%), Positives = 25/74 (33%), Gaps = 15/74 (20%)
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146
G LH+A + VE LV+ A +V + G+ LA
Sbjct: 101 YRGQTALHIAIERRCKHYVELLVEKGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 159
Query: 147 YGRNEVVSLMQANG 160
+ ++V + N
Sbjct: 160 TNQPDIVHYLTENA 173
>6BBJ-A nrPDB
Length = 868
Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats.
Identities = 21/98 (21%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115
G +H A ++ L+E ADV+ + G LPL LAA
Sbjct: 234 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 293
Query: 116 LRVVEFLVK--HTASNVGHRNHKGDTACD-LARLYGRN 150
+V +L + H +++ ++ +G+T L +
Sbjct: 294 PDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNT 331
Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats.
Identities = 28/151 (18%), Positives = 51/151 (33%), Gaps = 33/151 (21%)
Query: 37 FGRTALQVMKLGNPE-IARRLLLRGANPDLK---------DRTGF-----AVIHDAARAG 81
G+TAL + + L+ +GA+ + D G+ + AA
Sbjct: 233 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 292
Query: 82 FLDTLQTLLEF---QADVNIEDNEGNLPLH--LAAKEGHLRVVEFLVKHTASNVGHR--- 133
D + L E +AD+ +D+ GN LH +A + +F+ K V
Sbjct: 293 QPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKL 352
Query: 134 ----------NHKGDTACDLARLYGRNEVVS 154
N+ + +A G+ +
Sbjct: 353 YPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQ 383
Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats.
Identities = 32/160 (20%), Positives = 57/160 (35%), Gaps = 34/160 (21%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53
L A R + L++ +V+AQ FG L + P+I
Sbjct: 238 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 297
Query: 54 RRLLLRG---ANPDLKDRTGFAVIH-DAARAGF-----------LDTLQT-LLEFQADVN 97
L A+ +D G V+H A A D L ++ D +
Sbjct: 298 HYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSS 357
Query: 98 IE---DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRN 134
+E +N+ PL +AAK G + + + +++ + R+
Sbjct: 358 LEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARH 397
Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats.
Identities = 15/74 (20%), Positives = 25/74 (33%), Gaps = 15/74 (20%)
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146
G LH+A + VE LV+ A +V + G+ LA
Sbjct: 232 YRGQTALHIAIERRCKHYVELLVEKGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 290
Query: 147 YGRNEVVSLMQANG 160
+ ++V + N
Sbjct: 291 TNQPDIVHYLTENA 304
>2ETB-A nrPDB
Length = 256
Score = 53.0 bits (126), Expect = 6e-08, Method: Composition-based stats.
Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 35/164 (21%)
Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDLKDRT-------------GFA 72
VN + F G +AL + + + + L+ GA+ L+ G
Sbjct: 79 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 138
Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121
+ AA D + LLE A + D+ GN LH E V+
Sbjct: 139 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 198
Query: 122 -LVKHTASNV------GHRNHKGDTACDLARLYGRNEVVS-LMQ 157
L++ A NH+G T LA G+ E+ ++Q
Sbjct: 199 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 242
Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats.
Identities = 29/150 (19%), Positives = 55/150 (36%), Gaps = 33/150 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQN-------------GFGRTALQVM-KLGNPEIAR 54
L A + L+ + L++N +V+ + FG L + ++
Sbjct: 94 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 153
Query: 55 RLLL---RGANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADV------ 96
LL + A+ + D G V+H + LL+ A +
Sbjct: 154 YLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQL 213
Query: 97 -NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I +++G PL LAAKEG + + +++
Sbjct: 214 EEISNHQGLTPLKLAAKEGKIEIFRHILQR 243
Score = 30.7 bits (68), Expect = 0.35, Method: Composition-based stats.
Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 13/72 (18%)
Query: 103 GNLPLHLAA---KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGR 149
G L A ++G + L++ + V + G +A +A
Sbjct: 43 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRS 102
Query: 150 NEVVSLMQANGA 161
+ V L+ NGA
Sbjct: 103 LQCVKLLVENGA 114
>2F37-A nrPDB
Length = 251
Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats.
Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 17/98 (17%)
Query: 62 NPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGNLP 106
N D G + +H A L ++ L+E A+V+ G LP
Sbjct: 85 NAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELP 144
Query: 107 LHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142
L LAA VV +L+++ +++ + +G+T
Sbjct: 145 LSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLH 182
Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats.
Identities = 30/150 (20%), Positives = 52/150 (34%), Gaps = 33/150 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQN-------------GFGRTALQVM-KLGNPEIAR 54
L A + L+ + L++N NV+A+ FG L + ++
Sbjct: 99 LHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVS 158
Query: 55 RLLL---RGANPDLKDRTGFAVIHDAARAGFLDTLQT---------LLEFQADVN----- 97
LL + A+ D G V+H LL+ A +
Sbjct: 159 YLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQL 218
Query: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
I + + PL LAAKEG + + +++
Sbjct: 219 EDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248
Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats.
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 14/72 (19%)
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRN-------------HKGDTACDLARLY 147
G+ LH+A ++ L+ V+ LV++ A NV R + G+ LA
Sbjct: 93 YRGHSALHIAIEKRSLQCVKLLVENGA-NVHARACGRFFQKGQGTCFYFGELPLSLAACT 151
Query: 148 GRNEVVSLMQAN 159
+ +VVS + N
Sbjct: 152 KQWDVVSYLLEN 163
Score = 30.3 bits (67), Expect = 0.40, Method: Composition-based stats.
Identities = 25/122 (20%), Positives = 44/122 (36%), Gaps = 24/122 (19%)
Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF--QADVNIEDNE------GNLPLHLAA- 111
+P+ DR + +A G + L L E+ + + D+E G L A
Sbjct: 1 PDPNRFDRDR---LFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVL 57
Query: 112 --KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGRNEVVSLMQAN 159
K+G + L++ + V + G +A +A + V L+ N
Sbjct: 58 NLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVEN 117
Query: 160 GA 161
GA
Sbjct: 118 GA 119
>4XD0-A nrPDB
Length = 417
Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65
+E+ +A E ++ LL+ + +N G + + + GN ++ L+ +G N +
Sbjct: 293 DEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNIND 352
Query: 66 KDRTGFAVIH----DAARAGFLDTLQTLLEFQADVNIEDNEGNL 105
++ G V R+G L+ L+ D+ ++DNEG
Sbjct: 353 RNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLS 396
Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats.
Identities = 23/119 (19%), Positives = 52/119 (43%), Gaps = 5/119 (4%)
Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101
L + +PE +LL K+ G++ I AA G +D ++ L+ ++N +
Sbjct: 296 LTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNY 355
Query: 102 EGNL-PLHLA---AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156
+G ++ + G+ +E L+ ++ ++++G + D R E+ + M
Sbjct: 356 KGTTVAMYFKDYMLRSGNYTGLENLINLG-LDLFLKDNEGLSVFDYMRKNKNIELFNFM 413
Score = 33.0 bits (74), Expect = 0.059, Method: Composition-based stats.
Identities = 11/51 (21%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
Query: 110 AAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160
A ++ + L+K T + + +NH G + +A +G +V+ + + G
Sbjct: 298 ACEDKSPEFISKLLK-TENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKG 347
>3W9G-A nrPDB
Length = 260
Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats.
Identities = 20/98 (20%), Positives = 38/98 (38%), Gaps = 17/98 (17%)
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115
G +H A ++ L+E ADV+ + G LPL LAA
Sbjct: 93 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 152
Query: 116 LRVVEFLVKHT--ASNVGHRNHKGDTACD-LARLYGRN 150
+V +L ++ +++ ++ +G+T L +
Sbjct: 153 PHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNT 190
Score = 43.0 bits (100), Expect = 7e-05, Method: Composition-based stats.
Identities = 32/151 (21%), Positives = 55/151 (36%), Gaps = 34/151 (22%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53
L A R + L++ +V+AQ FG L + P I
Sbjct: 97 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIV 156
Query: 54 RRLLLRG---ANPDLKDRTGFAVIH--DAARAGFLDTLQ--------TLLEFQA---DVN 97
L G A+ +D G V+H A + + L++ D N
Sbjct: 157 HYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTN 216
Query: 98 IE---DNEGNLPLHLAAKEGHLRVVEFLVKH 125
+E +N+G PL +AAK G + + + +++
Sbjct: 217 LEALLNNDGLSPLMMAAKTGKIGIFQHIIRR 247
Score = 34.5 bits (78), Expect = 0.020, Method: Composition-based stats.
Identities = 16/74 (21%), Positives = 25/74 (33%), Gaps = 15/74 (20%)
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146
G LH+A + VE LV+ A +V + G+ LA
Sbjct: 91 YRGQTALHIAIERRCKHYVELLVEKGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 149
Query: 147 YGRNEVVSLMQANG 160
+ +V + NG
Sbjct: 150 TNQPHIVHYLTENG 163
Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats.
Identities = 22/105 (20%), Positives = 29/105 (27%), Gaps = 21/105 (20%)
Query: 78 ARAGFLDTLQTLLEF--QADVNIEDNE------GNLPLHLAA---KEGHLRVVEFLVKHT 126
G D L+ LL F + D E G L A G + L+
Sbjct: 13 VSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRNDTIPILLDIA 72
Query: 127 ASNVGHRNH----------KGDTACDLARLYGRNEVVSLMQANGA 161
R +G TA +A V L+ GA
Sbjct: 73 EKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGA 117
>6MHW-A nrPDB
Length = 826
Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 14/103 (13%)
Query: 37 FGRTALQVM-KLGNPEIARRLLLR-GANPDLKDRTGFAVIH-DAARAGFLDTLQTLLEFQ 93
FG T L + PEI + L+ + +D G ++H A T ++
Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRM 321
Query: 94 ADV-----------NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125
D+ +N+G PL LAAK G ++++++
Sbjct: 322 YDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364
Score = 46.5 bits (109), Expect = 5e-06, Method: Composition-based stats.
Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 12/101 (11%)
Query: 69 TGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLH----LAAK-EGHLRVVE-- 120
G + AA + +Q L+E Q D+ D+ GN LH +A + V+
Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRM 321
Query: 121 ---FLVKHTASNV-GHRNHKGDTACDLARLYGRNEVVSLMQ 157
L++ + RN+ G T LA G+ E++ +
Sbjct: 322 YDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYIL 362
Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats.
Identities = 33/159 (20%), Positives = 52/159 (32%), Gaps = 32/159 (20%)
Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLG----NPEIARRLLLRGANPDLKDR 68
R E + L + + + G+T L L EI R LL D+ R
Sbjct: 147 CRRRHDEDVPDFLMHKLTAS---DTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGR 203
Query: 69 -----------TGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EG 103
G ++ A D L+ ADVN G
Sbjct: 204 FINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFG 263
Query: 104 NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142
PL LAA +V+ L++H +++ R+ +G+
Sbjct: 264 ETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILH 302
>4DX2-A nrPDB
Length = 259
Score = 47.6 bits (112), Expect = 2e-06, Method: Composition-based stats.
Identities = 19/98 (19%), Positives = 37/98 (37%), Gaps = 17/98 (17%)
Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115
G +H A ++ L+ ADV+ + G LPL LAA
Sbjct: 91 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 150
Query: 116 LRVVEFLVKHT--ASNVGHRNHKGDTACD-LARLYGRN 150
+V +L ++ +++ ++ +G+T L +
Sbjct: 151 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNT 188
Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats.
Identities = 29/156 (18%), Positives = 52/156 (33%), Gaps = 36/156 (23%)
Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53
L A R + L+ +V+AQ FG L + P I
Sbjct: 95 LHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIV 154
Query: 54 RRLLLRG---ANPDLKDRTGFAVIH-DAARAGF----------------LDTLQTLLEFQ 93
L A+ +D G V+H A A L + +
Sbjct: 155 NYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSN 214
Query: 94 ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129
+ + +N+G PL +AAK G + + + +++ ++
Sbjct: 215 LEA-VLNNDGLSPLMMAAKTGKIGIFQHIIRREVTD 249
Score = 33.4 bits (75), Expect = 0.053, Method: Composition-based stats.
Identities = 15/73 (20%), Positives = 24/73 (32%), Gaps = 15/73 (20%)
Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146
G LH+A + VE LV A +V + G+ LA
Sbjct: 89 YRGQTALHIAIERRCKHYVELLVAQGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 147
Query: 147 YGRNEVVSLMQAN 159
+ +V+ + N
Sbjct: 148 TNQPHIVNYLTEN 160
Score = 27.6 bits (60), Expect = 2.8, Method: Composition-based stats.
Identities = 15/72 (20%), Positives = 20/72 (27%), Gaps = 13/72 (18%)
Query: 103 GNLPLHLAA---KEGHLRVVEFLVKHTASNVGHRNH----------KGDTACDLARLYGR 149
G L A G + L+ R +G TA +A
Sbjct: 44 GKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRC 103
Query: 150 NEVVSLMQANGA 161
V L+ A GA
Sbjct: 104 KHYVELLVAQGA 115
>5Z96-A nrPDB
Length = 755
Score = 45.7 bits (107), Expect = 9e-06, Method: Composition-based stats.
Identities = 31/144 (21%), Positives = 55/144 (38%), Gaps = 24/144 (16%)
Query: 3 EPWGNELASAAARGDLEQLTSLLQNN-----VNVNAQNGFGRTALQVMKLGNPEIARRLL 57
P +A +GD + L+ +N+N + GRTAL + LL
Sbjct: 30 SPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELL 89
Query: 58 LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ-------ADVNIEDNEGN------ 104
L N + G A++H A R + ++ LL + + D + +
Sbjct: 90 LS-FNVYV----GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDI 143
Query: 105 LPLHLAAKEGHLRVVEFLVKHTAS 128
P+ LAA + +++ LV+ S
Sbjct: 144 TPIILAAHTNNYEIIKLLVQKGVS 167
>4CJ9-A nrPDB
Length = 794
Score = 30.7 bits (68), Expect = 0.29, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 61/162 (37%), Gaps = 11/162 (6%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTG 70
A G + L ++L++ +N + +++ G + + +L A D + +
Sbjct: 586 AGNNGGAQALKAVLEHEATLNERGFSRADIVKIAGNGGGAQALKAVLEHEATLDERGFSR 645
Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130
++ A G L+ +LE +N + +AA G + ++ +++H +
Sbjct: 646 ADIVRIAGNGGGAQALKAVLEHGPTLNERGFNLTDIVEMAANSGGAQALKAVLEHGPTLR 705
Query: 131 GHRNHKGDTACDLA--RLYGRNEVVSLMQANG----AGGATN 166
+G + D+ G + + + G G +N
Sbjct: 706 ----QRGLSLIDIVEIASNGGAQALKAVLKYGPVLMQAGRSN 743
>3LJQ-A nrPDB
Length = 299
Score = 30.7 bits (68), Expect = 0.36, Method: Composition-based stats.
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 9/100 (9%)
Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65
NE+ +A A G E++ + ++ V N GRT Q K I + + RG +L
Sbjct: 198 DNEIGAATATGHGEEVIRTVGTHLVVELMNQ-GRTPQQACKEAVERIVKIVNRRGK--NL 254
Query: 66 KD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104
KD + GF ++ G ++ + + D +GN
Sbjct: 255 KDIQVGFIALNKKGEYG-----AYCIQDGFNFAVHDQKGN 289
>4WVX-A nrPDB
Length = 326
Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats.
Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 3/54 (5%)
Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLG--NPEIARRLLLRGANP 63
A+++G + + + AQ G + + G PE A LL GA+P
Sbjct: 147 ASSKGRITEYEKMFFRAA-ARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADP 199
>2DI3-A nrPDB
Length = 239
Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats.
Identities = 10/31 (32%), Positives = 16/31 (51%)
Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99
G+A +H +A G D + LLE D ++
Sbjct: 106 EGWAALHSSAERGDWDVAEALLEKMDDPSLP 136
>1HXH-A nrPDB
Length = 253
Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats.
Identities = 19/83 (22%), Positives = 28/83 (33%), Gaps = 8/83 (9%)
Query: 45 MKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104
E+ + LL GA D A AA G + DV+ E +
Sbjct: 15 ASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFV-----RHDVSSEADWT- 68
Query: 105 LPLHLAAKEGHLRVVEFLVKHTA 127
L +AA + L + LV +
Sbjct: 69 --LVMAAVQRRLGTLNVLVNNAG 89
>5Z56-q nrPDB
Length = 504
Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats.
Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 74 IHDAARAG------FLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127
+H A+ G +L AD N+ + + LA +GH + V +V H +
Sbjct: 216 LHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 275
Query: 128 SNV 130
++
Sbjct: 276 QDL 278
>4LG8-A nrPDB
Length = 354
Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats.
Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 74 IHDAARAG------FLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127
+H A+ G +L AD N+ + + LA +GH + V +V H +
Sbjct: 66 LHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 125
Query: 128 SNV 130
++
Sbjct: 126 QDL 128
>5XE7-A nrPDB
Length = 312
Score = 27.2 bits (59), Expect = 3.7, Method: Composition-based stats.
Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQ-NGFGRTALQV-MKLGNPEIARRLL 57
L +A A GDL+ + SLL +V + G+ V G+ ++ R +L
Sbjct: 183 RLMAAMAAGDLDTVVSLLHP--DVTFTGDSNGKAPTAVRAVRGSDKVVRFIL 232
>1JI6-A nrPDB
Length = 589
Score = 26.5 bits (57), Expect = 5.6, Method: Composition-based stats.
Identities = 14/65 (21%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query: 5 WGNELASAAARGDLEQLTSLLQNNVN-VNAQNGFGRTALQVMKLGNPEIARRLLLRGANP 63
++ A L +L L N + VNA N + +T L + + + R L + A
Sbjct: 55 IDKKIEEYAKSKALAELQGLQNNFEDYVNALNSWKKTPLSLRSKRSQDRIRELFSQ-AES 113
Query: 64 DLKDR 68
++
Sbjct: 114 HFRNS 118
>1KKT-A nrPDB
Length = 511
Score = 26.5 bits (57), Expect = 5.7, Method: Composition-based stats.
Identities = 9/52 (17%), Positives = 25/52 (48%), Gaps = 4/52 (7%)
Query: 27 NNVNVNAQNGFGRTALQV----MKLGNPEIARRLLLRGANPDLKDRTGFAVI 74
+N + +++NG+G +A+ + +G ++ +L A+ D + +
Sbjct: 69 SNGHADSRNGWGASAVDALSTAVIMGKADVVNAILEHVADIDFSKTSDTVSL 120
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.310 0.144 0.381
Lambda K H
0.267 0.0444 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,122,898
Number of Sequences: 36641
Number of extensions: 222496
Number of successful extensions: 1755
Number of sequences better than 10.0: 85
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 577
Number of HSP's gapped (non-prelim): 483
length of query: 168
length of database: 10,336,785
effective HSP length: 90
effective length of query: 78
effective length of database: 7,039,095
effective search space: 549049410
effective search space used: 549049410
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 56 (26.1 bits)