BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P42773 (168 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1G3N-B nrPDB 339 4e-94 1BLX-B nrPDB 135 8e-33 1BD8-A nrPDB 130 3e-31 2A5E-A nrPDB 93 5e-20 5AQ9-A nrPDB 92 9e-20 1D9S-A nrPDB 91 3e-19 5H76-A nrPDB 87 5e-18 5AQB-A nrPDB 87 5e-18 6FES-A nrPDB 78 1e-15 5AQ7-A nrPDB 78 2e-15 2DWZ-A nrPDB 75 1e-14 5AQA-A nrPDB 75 2e-14 4NIK-A nrPDB 74 3e-14 6MWQ-A nrPDB 72 8e-14 5MIO-C nrPDB 72 1e-13 5CBO-A nrPDB 71 2e-13 5GP7-A nrPDB 60 3e-10 5JHQ-A nrPDB 58 2e-09 5ET1-A nrPDB 57 4e-09 3B7B-A nrPDB 57 5e-09 6BY9-A nrPDB 56 7e-09 5HKP-A nrPDB 56 7e-09 4Z68-A nrPDB 54 4e-08 1WG0-A nrPDB 52 1e-07 3EU9-A nrPDB 52 2e-07 3UI2-A nrPDB 49 9e-07 3DEO-A nrPDB 48 2e-06 3EHQ-A nrPDB 47 3e-06 4O1O-A nrPDB 46 1e-05 6AUN-A nrPDB 45 1e-05 5DND-A nrPDB 43 5e-05 4OAU-C nrPDB 43 5e-05 5U0K-A nrPDB 42 9e-05 4OT9-A nrPDB 42 2e-04 5UQE-A nrPDB 42 2e-04 5U0J-A nrPDB 40 4e-04 6EMK-G nrPDB 40 4e-04 5D68-A nrPDB 39 0.001 3LJN-A nrPDB 35 0.012 2KXP-C nrPDB 35 0.017 3ZKJ-A nrPDB 34 0.032 4BSZ-B nrPDB 33 0.045 6BOA-A nrPDB 32 0.12 6GYM-3 nrPDB 32 0.19 6E2G-A nrPDB 31 0.24 2ISQ-A nrPDB 31 0.24 1DCQ-A nrPDB 31 0.25 4AEC-A nrPDB 31 0.29 3T9K-A nrPDB 31 0.30 2RFA-A nrPDB 31 0.32 4LMA-A nrPDB 30 0.42 3LVQ-E nrPDB 30 0.46 5WP0-A nrPDB 30 0.54 2B0O-E nrPDB 30 0.69 6DMR-A nrPDB 30 0.70 6CUD-A nrPDB 30 0.73 3Q4G-A nrPDB 29 0.81 1W5T-A nrPDB 29 0.81 6CV9-A nrPDB 29 0.88 1XLT-A nrPDB 28 1.5 4QJ1-A nrPDB 28 1.5 6DJS-A nrPDB 28 1.6 3T4P-A nrPDB 28 1.6 3FFS-A nrPDB 28 1.7 2NYJ-A nrPDB 28 1.8 5IRX-A nrPDB 28 1.9 4LMB-A nrPDB 28 2.0 4LG1-A nrPDB 27 3.1 6ED3-A nrPDB 27 4.6 6DVZ-A nrPDB 27 4.8 5XE7-A nrPDB 27 5.2 3AUJ-A nrPDB 26 7.0 4XD0-A nrPDB 26 7.7 2RON-A nrPDB 26 8.1 6BO5-A nrPDB 26 8.3 5HI9-A nrPDB 26 8.3 >1G3N-B nrPDB Length = 168 Score = 339 bits (869), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 168/168 (100%), Positives = 168/168 (100%) Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG Sbjct: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60 Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE Sbjct: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ Sbjct: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 >1BLX-B nrPDB Length = 166 Score = 135 bits (340), Expect = 8e-33, Method: Compositional matrix adjust. Identities = 72/155 (46%), Positives = 106/155 (68%), Gaps = 3/155 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+P +A LL +GA+P+ Sbjct: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPN 68 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 ++D +G + +HDAAR GFLDTL+ L+E ADVN D+ G+LP+HLA +EGH VV FL Sbjct: 69 VQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAP 128 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 S++ HR+ G T +LAR G ++ ++Q + Sbjct: 129 E--SDLHHRDASGLTPLELARQRGAQNLMDILQGH 161 >1BD8-A nrPDB Length = 156 Score = 130 bits (327), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 71/155 (45%), Positives = 104/155 (67%), Gaps = 3/155 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+ IA LL +GA+P+ Sbjct: 3 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 62 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 ++D +G + +HDAAR GFLDTL+ L+E ADVN+ D G LP+HLA +EGH VV FL Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAA 122 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 S++ R+ +G T +LA G ++V ++Q + Sbjct: 123 E--SDLHRRDARGLTPLELALQRGAQDLVDILQGH 155 >2A5E-A nrPDB Length = 156 Score = 93.2 bits (230), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Query: 3 EPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN 62 EP + LA+AAARG +E++ +LL+ NA N +GR +QVM +G+ +A LLL GA Sbjct: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAE 69 Query: 63 PDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 P+ D +HDAAR GFLDTL L A +++ D G LP+ LA + GH V + Sbjct: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129 Query: 122 LVKHTASNVGHRNHKGDTA 140 L G + + D A Sbjct: 130 LRAAAGGTRGSNHARIDAA 148 >5AQ9-A nrPDB Length = 422 Score = 92.4 bits (228), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 62/157 (39%), Positives = 90/157 (57%), Gaps = 2/157 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 134 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 H A +V ++ G T DLA G ++V +L+Q A Sbjct: 135 HGA-DVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAA 170 >1D9S-A nrPDB Length = 136 Score = 90.5 bits (223), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 50/115 (43%), Positives = 70/115 (60%), Gaps = 1/115 (0%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDR 68 LA+AAARG +E + LL+ + NA N FGR +QVM +G+ ++A LLL GA P+ D Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCADP 75 Query: 69 TGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122 +HDAAR GFLDTL L A +++ D G LP+ LA ++GH + +L Sbjct: 76 ATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYL 130 >5H76-A nrPDB Length = 201 Score = 86.7 bits (213), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 57/152 (37%), Positives = 86/152 (56%), Gaps = 3/152 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D Sbjct: 7 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 66 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K Sbjct: 67 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 126 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 H A N ++ G TA D++ G ++ ++ Sbjct: 127 HGAVNA--QDKFGKTAFDISIDNGNEDLAQIL 156 Score = 66.2 bits (160), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 40/86 (46%), Positives = 52/86 (60%), Gaps = 1/86 (1%) Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135 +AARAG D ++ L+ ADVN DN G PLHLAA GHL +VE L+KH A +V + Sbjct: 12 EAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGA-DVDASDV 70 Query: 136 KGDTACDLARLYGRNEVVSLMQANGA 161 G T LA +G E+V ++ NGA Sbjct: 71 FGYTPLHLAAYWGHLEIVEVLLKNGA 96 >5AQB-A nrPDB Length = 428 Score = 86.7 bits (213), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 56/151 (37%), Positives = 85/151 (56%), Gaps = 1/151 (0%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65 G +L AA G ++ L+ N +VNA + G T L + G+ EI LL GA+ + Sbjct: 15 GKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVNA 74 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 D G+ +H AA +G L+ ++ LL++ ADVN +D G PLHLAA GHL +VE L+K+ Sbjct: 75 ADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKN 134 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 A +V ++ G T DLA G ++ ++ Sbjct: 135 GA-DVNAQDKFGKTPRDLAIDNGNEDIAEVL 164 Score = 74.3 bits (181), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 47/125 (37%), Positives = 71/125 (56%), Gaps = 2/125 (1%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 G+ L+ + G + R L+ GA+ + D G+ +H AA G L+ ++ LL+ ADV Sbjct: 14 LGKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGADV 72 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 N D +G PLHLAA GHL +VE L+K+ A +V + G T LA ++G E+V ++ Sbjct: 73 NAADIDGYTPLHLAAFSGHLEIVEVLLKYGA-DVNADDQAGFTPLHLAAIFGHLEIVEVL 131 Query: 157 QANGA 161 NGA Sbjct: 132 LKNGA 136 Score = 62.8 bits (151), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 48/130 (36%), Positives = 66/130 (50%), Gaps = 9/130 (6%) Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTGF 71 AA G LE + LL+N +VNA + G T L + G+ EI LL GA+ + D+ GF Sbjct: 54 AAWGHLEIVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGF 113 Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL--------V 123 +H AA G L+ ++ LL+ ADVN +D G P LA G+ + E L V Sbjct: 114 TPLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAATLVKV 173 Query: 124 KHTASNVGHR 133 K A +G R Sbjct: 174 KDAADQLGAR 183 >6FES-A nrPDB Length = 367 Score = 78.2 bits (191), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 49/125 (39%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ ADV Sbjct: 6 LGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 65 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 N D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V ++ Sbjct: 66 NANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-VNATDVIGTAPLHLAAMWGHEEIVEVL 124 Query: 157 QANGA 161 NGA Sbjct: 125 LKNGA 129 Score = 64.3 bits (155), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 41/87 (47%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135 +AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V + Sbjct: 12 EAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNANDE 70 Query: 136 KGDTACDLARLYGRNEVVSLMQANGAG 162 +G T LA G E+V ++ NGAG Sbjct: 71 RGHTPLHLAAYTGHLEIVEVLLKNGAG 97 Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 47/144 (32%), Positives = 61/144 (42%), Gaps = 33/144 (22%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGF 71 AA G L + LL+N +VNA + G T L Sbjct: 46 AAWEGHLGIVEVLLKNGADVNANDERGHTPL----------------------------- 76 Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 H AA G L+ ++ LL+ A VN D G PLHLAA GH +VE L+K+ A + Sbjct: 77 ---HLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLKNGA-DAR 132 Query: 132 HRNHKGDTACDLARLYGRNEVVSL 155 ++ G T DLAR G V L Sbjct: 133 AQDKFGKTPEDLARDNGYESVARL 156 Score = 25.8 bits (55), Expect = 9.6, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPE----IARRLLLRGANPDLKD 67 AA G E + LL+N + AQ+ FG+T + + E +AR+ ++R +LK+ Sbjct: 112 AAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARLARKEIIRAVVDELKE 171 >5AQ7-A nrPDB Length = 418 Score = 77.8 bits (190), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 48/125 (38%), Positives = 68/125 (54%), Gaps = 1/125 (0%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ ADV Sbjct: 14 LGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADV 73 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 N D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V ++ Sbjct: 74 NANDERGHTPLHLAAYTGHLEIVEVLLKNGA-GVNATDVIGTAPLHLAAMWGYKEIVEVL 132 Query: 157 QANGA 161 GA Sbjct: 133 LKAGA 137 Score = 65.9 bits (159), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 41/87 (47%), Positives = 53/87 (60%), Gaps = 1/87 (1%) Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135 +AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V + Sbjct: 20 EAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNANDE 78 Query: 136 KGDTACDLARLYGRNEVVSLMQANGAG 162 +G T LA G E+V ++ NGAG Sbjct: 79 RGHTPLHLAAYTGHLEIVEVLLKNGAG 105 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 43/113 (38%), Positives = 60/113 (53%), Gaps = 1/113 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70 AA G L + LL+N +VNA + G T L + G+ EI LL GA + D G Sbjct: 54 AAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIG 113 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 A +H AA G+ + ++ LL+ ADV+ +D G PL LAA +GH + LV Sbjct: 114 TAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166 >2DWZ-A nrPDB Length = 231 Score = 75.5 bits (184), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 51/118 (43%), Positives = 62/118 (52%), Gaps = 1/118 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDLKDRTG 70 AA+ G E + +LL +VNA N G T L N EIA LL GANPD KD Sbjct: 80 AASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYD 139 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128 +H AA G L + LL ++A NI+D EGN PLHLA E + +FLV AS Sbjct: 140 ATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGAS 197 Score = 34.7 bits (78), Expect = 0.020, Method: Compositional matrix adjust. Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 2/90 (2%) Query: 73 VIHDAARAGFLDTLQT-LLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 +I + A +G LD L+ +L ++ D + LH A GH +VEFL++ V Sbjct: 9 MICNLAYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ-LGVPVN 67 Query: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161 ++ G + +A GR+E+V + GA Sbjct: 68 DKDDAGWSPLHIAASAGRDEIVKALLVKGA 97 >5AQA-A nrPDB Length = 418 Score = 74.7 bits (182), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 47/125 (37%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ ADV Sbjct: 14 LGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADV 73 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 + D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V ++ Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYKEIVEVL 132 Query: 157 QANGA 161 GA Sbjct: 133 LKAGA 137 Score = 66.6 bits (161), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 42/113 (37%), Positives = 63/113 (55%), Gaps = 1/113 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70 AA G LE + LL++ +V+A + FG T L + G+ EI LL GA+ + D G Sbjct: 54 AAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDG 113 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 +H AA+ G+ + ++ LL+ ADV+ +D G PL LAA +GH + LV Sbjct: 114 MTPLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLV 166 >4NIK-A nrPDB Length = 230 Score = 73.9 bits (180), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 50/118 (42%), Positives = 60/118 (50%), Gaps = 1/118 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDLKDRTG 70 AA+ G E + +LL VNA N G T L N EIA LL GANPD KD Sbjct: 84 AASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYE 143 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128 +H AA G L + LL ++A NI+D EGN PLHLA E + + LV AS Sbjct: 144 ATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 201 Score = 33.5 bits (75), Expect = 0.050, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Query: 73 VIHDAARAGFLDTL-QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 ++ + A +G L+ L +++L ++ D + LH A GH +VEFL++ V Sbjct: 13 MVCNLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQ-LGVPVN 71 Query: 132 HRNHKGDTACDLARLYGRNEVVSLMQANGA 161 ++ G + +A GR+E+V + GA Sbjct: 72 DKDDAGWSPLHIAASAGRDEIVKALLGKGA 101 >6MWQ-A nrPDB Length = 493 Score = 72.4 bits (176), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 46/125 (36%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 G+ L+ + G + R L+ GA+ + DR G +H AA+ G L+ ++ LL+ ADV Sbjct: 5 LGKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADV 64 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 N D G PLHLAA GHL +VE L+K+ A +V + G T L + G E+V ++ Sbjct: 65 NAADLWGQTPLHLAATAGHLEIVEVLLKYGA-DVNALDLIGKTPLHLTAIDGHLEIVEVL 123 Query: 157 QANGA 161 +GA Sbjct: 124 LKHGA 128 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 42/123 (34%), Positives = 64/123 (52%), Gaps = 1/123 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70 AA RG LE + LL+ +VNA + +G+T L + G+ EI LL GA+ + D G Sbjct: 45 AAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIG 104 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 +H A G L+ ++ LL+ ADVN +D G ++ G+ + E L K S++ Sbjct: 105 KTPLHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLNLSDI 164 Query: 131 GHR 133 HR Sbjct: 165 AHR 167 >5MIO-C nrPDB Length = 573 Score = 72.0 bits (175), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 46/125 (36%), Positives = 70/125 (56%), Gaps = 1/125 (0%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 G+ L+ + G + R L+ GA+ + D +G +H AA G L+ ++ LL+ ADV Sbjct: 410 LGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADV 469 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 + D G+ PLHLAA GHL +VE L+KH A +V + GDT LA + G ++V + Sbjct: 470 SASDLMGSTPLHLAALIGHLEIVEVLLKHGA-DVNAVDTWGDTPLRLAAVMGHLKIVEAL 528 Query: 157 QANGA 161 +GA Sbjct: 529 LKHGA 533 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTG 70 AA G LE + LL++ +V+A + G T L + L G+ EI LL GA+ + D G Sbjct: 450 AATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWG 509 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 + AA G L ++ LL+ ADVN +D G + G + E L K Sbjct: 510 DTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563 Score = 33.5 bits (75), Expect = 0.051, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%) Query: 3 EPWGN-ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTA 41 + WG+ L AA G L+ + +LL++ +VNAQ+ FG+TA Sbjct: 506 DTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTA 545 >5CBO-A nrPDB Length = 176 Score = 71.2 bits (173), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 43/125 (34%), Positives = 69/125 (55%), Gaps = 1/125 (0%) Query: 37 FGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADV 96 G+ L+ G + R L+ GA+ + D G +H AA G + ++ LL++ ADV Sbjct: 3 LGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADV 62 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 N D G+ PLHLAAK G+L +VE L+K+ A +V ++ G TA D++ G ++ ++ Sbjct: 63 NASDATGDTPLHLAAKWGYLGIVEVLLKYGA-DVNAQDKFGKTAFDISIDNGNEDLAEIL 121 Query: 157 QANGA 161 N A Sbjct: 122 CKNKA 126 Score = 65.5 bits (158), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 42/123 (34%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + FG T L + G+ EI LL GA+ + Sbjct: 4 GKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVN 63 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D TG +H AA+ G+L ++ LL++ ADVN +D G ++ G+ + E L K Sbjct: 64 ASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCK 123 Query: 125 HTA 127 + A Sbjct: 124 NKA 126 >5GP7-A nrPDB Length = 169 Score = 60.5 bits (145), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 44/138 (31%), Positives = 67/138 (48%), Gaps = 3/138 (2%) Query: 9 LASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA +G L ++ L N+N G T L + N E+A LL GA+ + + Sbjct: 13 LLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 72 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D+ G +H+AA G +D L+++ VN D PLH AA++G ++ L+ H Sbjct: 73 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHG 132 Query: 127 ASNVGHRNHKGDTACDLA 144 A +N +G T DLA Sbjct: 133 ADPT-MKNQEGQTPLDLA 149 Score = 43.1 bits (100), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 1/103 (0%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLKDRTG 70 AA +LE LL++ +VNAQ+ G L G+ +IA L+ + D+ Sbjct: 50 AAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWA 109 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKE 113 F +H+AA+ G LL AD +++ EG PL LA + Sbjct: 110 FTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATAD 152 >5JHQ-A nrPDB Length = 482 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 48/141 (34%), Positives = 70/141 (49%), Gaps = 7/141 (4%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV---MKLGNPEIARRLLLRGANPD 64 EL A GD+ ++ L+ + NVNA++ GR + + G ++ LL GAN Sbjct: 18 ELLEACRNGDVSRVKRLV-DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVH 76 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 +D G +H+A G + + LL AD N DN PLH AA +G + V L++ Sbjct: 77 ARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQ 136 Query: 125 HTA-SNVGHRNHKGDTACDLA 144 H A N+ RN G +A DLA Sbjct: 137 HGADPNI--RNTDGKSALDLA 155 Score = 56.2 bits (134), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%) Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64 +EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+ Sbjct: 170 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 229 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+ Sbjct: 230 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 289 Query: 125 HTASNVGHRNHKGDTACDLA 144 H A H G +A D+A Sbjct: 290 HGADPTLVNCH-GKSAVDMA 308 Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 4/124 (3%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV----MKLGNPEIARRLLLRGA 61 G+ L AA DL ++ L + Q TAL + ++ LL +GA Sbjct: 323 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 382 Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 N + K++ +H AA D ++ L + A +N D G LH AA GHL+ Sbjct: 383 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 442 Query: 122 LVKH 125 L+ + Sbjct: 443 LLSY 446 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 32/88 (36%), Positives = 47/88 (53%), Gaps = 4/88 (4%) Query: 76 DAARAGFLDTLQTLLEFQADVNIEDNEG--NLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 +A R G + ++ L++ A+VN +D G + PLH AA G VVE L++ +NV R Sbjct: 21 EACRNGDVSRVKRLVD-AANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQ-MGANVHAR 78 Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGA 161 + G A +G EVVSL+ GA Sbjct: 79 DDGGLIPLHNACSFGHAEVVSLLLCQGA 106 Score = 31.2 bits (69), Expect = 0.21, Method: Compositional matrix adjust. Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 30/180 (16%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRL--------LLRG 60 L AA++ +E + LL + + N G++A+ + PE+ RL LL+ Sbjct: 272 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAP--TPELRERLTYEFKGHSLLQA 329 Query: 61 AN----PDLKDRTGFAVI-------HDAARAGFLDTL--------QTLLEFQADVNIEDN 101 A +K +I H+ A + +L + LL A+VN ++ Sbjct: 330 AREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNK 389 Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + PLH+AA+ H V+E L KH A + + G TA A L G + L+ + G+ Sbjct: 390 DFMTPLHVAAERAHNDVMEVLHKHGA-KMNALDTLGQTALHRAALAGHLQTCRLLLSYGS 448 >5ET1-A nrPDB Length = 353 Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 38/188 (20%) Query: 12 AAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRG-ANPDLKDR 68 AAA G L L LL Q V ++ G T L + + G+P++ + LL +G AN + Sbjct: 78 AAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTD 137 Query: 69 TGFAVIHDAARAGFLDTLQTLL-----------------------------------EFQ 93 TG IH AA G L +L+ L+ E Sbjct: 138 TGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECS 197 Query: 94 ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVV 153 AD ++ +G PLH AA+ GH V+ +LV + ++H G TA A G +V+ Sbjct: 198 ADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVL 257 Query: 154 SLMQANGA 161 S + +GA Sbjct: 258 SWLLLHGA 265 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 52/177 (29%), Positives = 79/177 (44%), Gaps = 37/177 (20%) Query: 12 AAARGDLEQLTSLLQNNVN-VNAQNGFGRTALQV-MKLGNPEIARRLLLR-GANPDLKDR 68 AAA+GDL L L+ + VNAQ G T L + + G+ E+ + L+ A+P L+ + Sbjct: 146 AAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQ 205 Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNI--EDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 G +H AA+ G L L+ F ADV+ +D++G +H AA GH +V+ +L+ H Sbjct: 206 DGMTPLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHG 264 Query: 127 A-------------------------------SNVGHRNHKGDTACDLARLYGRNEV 152 A + + R+H G TA DLA G Sbjct: 265 AEISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHC 321 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 37/122 (30%), Positives = 58/122 (47%), Gaps = 2/122 (1%) Query: 41 ALQVMKLGNPEIARRLLLRGA-NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 ALQ + G+ ++ R L G P L+D +H AAR+G L L+ L+E A + Sbjct: 7 ALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVS 66 Query: 100 D-NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158 G P H AA G+L +++L+ V +++ G T LA +G +VV + Sbjct: 67 RARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLY 126 Query: 159 NG 160 G Sbjct: 127 QG 128 Score = 39.3 bits (90), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 2/117 (1%) Query: 28 NVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTL 86 +V+ + Q+ G TA+ G+ ++ LLL GA +D G +HDAA G L+ Sbjct: 231 DVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS-QDLWGGTPLHDAAENGELECC 289 Query: 87 QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDL 143 Q L A +++ D++G LA GH +L ++ HR D + DL Sbjct: 290 QILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTVQTLSLEHRVLSRDQSMDL 346 >3B7B-A nrPDB Length = 237 Score = 56.6 bits (135), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 46/153 (30%), Positives = 83/153 (54%), Gaps = 7/153 (4%) Query: 12 AAARGDLEQLTSLLQN-NVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDLKDRT 69 AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++D Sbjct: 84 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 143 Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLR-VVEFLVKHTAS 128 +H AA +G +D + LL + D++ + G+ PLH+AA+E VV FL + S Sbjct: 144 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR--DS 201 Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 +V +N +G+T A L ++V S +Q + A Sbjct: 202 DVTLKNKEGETPLQCASL--NSQVWSALQMSKA 232 Score = 52.8 bits (125), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 35/114 (30%), Positives = 61/114 (53%) Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107 G+ +I L+ GAN D + +AA L+ ++ L++ A V+ +D EG+ L Sbjct: 22 GHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCL 81 Query: 108 HLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 HLAAK+GH VV++L+ + +V ++ G T A Y ++V L+ + G+ Sbjct: 82 HLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 135 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 1/87 (1%) Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 +H AA AG +D L++ A+++ + PL AA+ HL V++L+K + V + Sbjct: 15 LHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIK-AGALVDPK 73 Query: 134 NHKGDTACDLARLYGRNEVVSLMQANG 160 + +G T LA G EVV + +NG Sbjct: 74 DAEGSTCLHLAAKKGHYEVVQYLLSNG 100 >6BY9-A nrPDB Length = 328 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 43/152 (28%), Positives = 80/152 (52%), Gaps = 5/152 (3%) Query: 12 AAARGDLEQLTSLLQN-NVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDLKDRT 69 AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++D Sbjct: 175 AAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNE 234 Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129 +H AA +G +D + LL + D++ + G+ PLH+AA+E V + S+ Sbjct: 235 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRD-SD 293 Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 V +N +G+T A L ++V S +Q + A Sbjct: 294 VTLKNKEGETPLQCASL--NSQVWSALQMSKA 323 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 43/158 (27%), Positives = 84/158 (53%), Gaps = 3/158 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVN--AQNGFGRTALQVM-KLGNPEIARRLLLRGANP 63 +L +A +G+L+++ +L + ++ N ++ R+ L + G+ +I L+ GAN Sbjct: 69 KQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI 128 Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 D + +AA L+ ++ L++ A V+ +D EG+ LHLAAK+GH VV++L+ Sbjct: 129 DTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLL 188 Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + +V ++ G T A Y ++V L+ + G+ Sbjct: 189 SNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 226 >5HKP-A nrPDB Length = 351 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%) Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64 +EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+ Sbjct: 26 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 85 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+ Sbjct: 86 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 145 Query: 125 HTASNVGHRNHKGDTACDLA 144 H A H G +A D+A Sbjct: 146 HGADPTLVNCH-GKSAVDMA 164 Score = 41.6 bits (96), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 35/124 (28%), Positives = 55/124 (44%), Gaps = 4/124 (3%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV----MKLGNPEIARRLLLRGA 61 G+ L AA DL ++ L + Q TAL + ++A LL +GA Sbjct: 179 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGA 238 Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 N + K++ +H AA D ++ L + A +N D+ G LH AA GHL+ Sbjct: 239 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRL 298 Query: 122 LVKH 125 L+ + Sbjct: 299 LLSY 302 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 30/180 (16%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRL--------LLRG 60 L AA++ +E + LL + + N G++A+ + PE+ RL LL+ Sbjct: 128 LHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAP--TPELRERLTYEFKGHSLLQA 185 Query: 61 AN----PDLKDRTGFAVI-------HDAARAGFLDTL--------QTLLEFQADVNIEDN 101 A +K +I H+ A + +L + LL A+VN ++ Sbjct: 186 AREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNK 245 Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + PLH+AA+ H V+E L KH A + + G TA A L G + L+ + G+ Sbjct: 246 DFMTPLHVAAERAHNDVMEVLHKHGA-KMNALDSLGQTALHRAALAGHLQTCRLLLSYGS 304 >4Z68-A nrPDB Length = 155 Score = 53.5 bits (127), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 64/140 (45%), Gaps = 3/140 (2%) Query: 8 ELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDL 65 +L AA GD+E + L +VN G T L N + LL GA+ Sbjct: 6 QLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 KD+ G +H+A G + + L++ A VN+ D PLH AA +G + + L++H Sbjct: 66 KDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQH 125 Query: 126 TASNVGHRNHKGDTACDLAR 145 A +N G+T DL + Sbjct: 126 GADPTK-KNRDGNTPLDLVK 144 Score = 29.3 bits (64), Expect = 0.96, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 1/53 (1%) Query: 1 MAEPWG-NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEI 52 +A+ W L AAA+G E LLQ+ + +N G T L ++K G+ +I Sbjct: 98 VADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGDTDI 150 >1WG0-A nrPDB Length = 243 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 40/127 (31%), Positives = 61/127 (48%), Gaps = 7/127 (5%) Query: 20 QLTSLL---QNNVNVN-AQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLKDRT--GFA 72 ++TS L NVN++ + G T + +GN E+ + L R PDL T G Sbjct: 50 EITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVT 109 Query: 73 VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132 +H A + + Q L+E A V I+D +PLH AA G L+++E L S V Sbjct: 110 CLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNW 169 Query: 133 RNHKGDT 139 ++ +G T Sbjct: 170 QDKQGWT 176 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 6/138 (4%) Query: 12 AAARGDLEQLTSLLQNNV--NVNAQNGFGRTALQVMKLGNP--EIARRLLLRGANPDLKD 67 A + G+LE + SL + ++N G T L + +G E+++ L+ GA+ +KD Sbjct: 79 ACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLH-LAVGKKWFEVSQFLIENGASVRIKD 137 Query: 68 RTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 + +H AA G L ++ L ++ VN +D +G PL A EGH LV+ Sbjct: 138 KFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKY 197 Query: 127 ASNVGHRNHKGDTACDLA 144 + ++KG A D+A Sbjct: 198 GAEYDLVDNKGAKAEDVA 215 >3EU9-A nrPDB Length = 240 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 40/140 (28%), Positives = 70/140 (50%), Gaps = 4/140 (2%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDLKD 67 L A +G L + L++ + + +G G + + + + G+ I L+ +G + D+ D Sbjct: 80 LHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMD 139 Query: 68 RTGFAVIHDAA-RAGFLDTLQTLLEFQADVNIEDN-EGNLPLHLAAKEGHLRVVEFLVKH 125 + G + AA R +D + LL F VN+ D N LH A G+ V+ L++ Sbjct: 140 QNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLE- 198 Query: 126 TASNVGHRNHKGDTACDLAR 145 +NV +N KG++A DLA+ Sbjct: 199 AGANVDAQNIKGESALDLAK 218 Score = 49.7 bits (117), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 39/116 (33%), Positives = 57/116 (49%), Gaps = 3/116 (2%) Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107 G+ + +L+ GA+P L D G + IH AA+ G + L+ DV++ D G PL Sbjct: 87 GHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPL 146 Query: 108 HLAAKEGH-LRVVEFLVKHTAS-NVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 AA H + L+ S N+G + HK +TA A L G V+SL+ GA Sbjct: 147 MWAAYRTHSVDPTRLLLTFNVSVNLGDKYHK-NTALHWAVLAGNTTVISLLLEAGA 201 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD-L 65 ++ A G E+ L++ +V + T L + N ++ + + +GA D L Sbjct: 12 DIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQL 71 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 +H A R G L + L+++ AD ++ D EG +HLAA+ GH +V +L+ Sbjct: 72 GGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLI 129 Score = 36.2 bits (82), Expect = 0.006, Method: Compositional matrix adjust. Identities = 30/120 (25%), Positives = 59/120 (49%), Gaps = 2/120 (1%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN-IED 100 ++ + G E R L+ G + D+ ++H AA +D ++ + A V+ + Sbjct: 14 VKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGG 73 Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 + + PLH A ++GHL +V L+K+ A + + +G + LA +G +V+ + A G Sbjct: 74 DLNSTPLHWATRQGHLSMVVQLMKYGA-DPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKG 132 >3UI2-A nrPDB Length = 244 Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%) Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62 PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+ Sbjct: 48 PW----WTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102 Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 D +D R G +H AA + ++ L+E AD+ +ED G L LA Sbjct: 103 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151 >3DEO-A nrPDB Length = 183 Score = 48.1 bits (113), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%) Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62 PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+ Sbjct: 47 PWW----TAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101 Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 D +D R G +H AA + ++ L+E AD+ +ED G L LA Sbjct: 102 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150 >3EHQ-A nrPDB Length = 222 Score = 47.4 bits (111), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 30/88 (34%), Positives = 44/88 (50%) Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 +H+AA+ G L L+ L+ + VN D G+ L+ A GH +VE L + + Sbjct: 77 LHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQQ 136 Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGA 161 N GDTA A G ++V L+ A GA Sbjct: 137 NKLGDTALHAAAWKGYADIVQLLLAKGA 164 Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/111 (32%), Positives = 51/111 (45%), Gaps = 2/111 (1%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61 AE N L AA RG+L L L N V VN + G TAL G + +L Sbjct: 70 AESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQP 129 Query: 62 NPDL--KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 N +L +++ G +H AA G+ D +Q LL A ++ + E L +A Sbjct: 130 NIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA 180 >4O1O-A nrPDB Length = 717 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 2/120 (1%) Query: 43 QVMKLGNPEIARRLLLRGANPDLKDRT-GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101 Q ++ + E R+LL RGA+ + ++ G++ +H A + D + LL+ AD + Sbjct: 14 QAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKR 73 Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 G P +A G++R+++ L+ + +V + G TA A +YGR E + + NGA Sbjct: 74 NGATPFIIAGITGNVRLLQLLLPNV-EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGA 132 Score = 44.3 bits (103), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 2/132 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQ-VMKLGNPEIARRLLLRGANPDLK 66 L A D+EQ+ LL+ + N Q +G + L +++ + ++ LL GA+P L+ Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLR 71 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 R G A G + LQ LL DVN D G AA G + + FL ++ Sbjct: 72 KRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENG 131 Query: 127 ASNVGHRNHKGD 138 A HR K D Sbjct: 132 ADVNMHRKTKQD 143 >6AUN-A nrPDB Length = 752 Score = 45.1 bits (105), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 61/132 (46%), Gaps = 4/132 (3%) Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFA 72 + +G E + S+ + ++ + +G + L K N E+AR LL RG + D G Sbjct: 263 SQKGCAEMIISMDSSQIH-SKDPRYGASPLHWAK--NAEMARMLLKRGCDVDSTSAAGNT 319 Query: 73 VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132 +H A D + LL + A+ GN PLHLA + ++ +++ L+ A V Sbjct: 320 ALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIKALIVFGA-EVDT 378 Query: 133 RNHKGDTACDLA 144 N G+T +A Sbjct: 379 PNDFGETPAFMA 390 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 46/99 (46%) Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 ++ + V H A G + + E+ EG PLHLA ++G ++ LV+ Sbjct: 114 IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQ 173 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGG 163 + + + ++KG+TA A ++V+ L+ N + G Sbjct: 174 YCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAG 212 Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/88 (27%), Positives = 47/88 (53%), Gaps = 1/88 (1%) Query: 70 GFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128 G +H A R G + L L+++ A +++ DN+G H A + + +V++ L K+ ++ Sbjct: 152 GCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASA 211 Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLM 156 + N +G T LA G+ E+V ++ Sbjct: 212 GLNQVNKQGLTPLHLACQMGKQEMVRVL 239 >5DND-A nrPDB Length = 588 Score = 43.1 bits (100), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 9/164 (5%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRT-ALQVMKLGNPEIARRLLLRG 60 + P G+ L AR L SL + Q+ + AL + G E + L+ G Sbjct: 391 SSPPGSTLGQGVAR-----LFSLFGCQEEDSVQDAVMPSLALALAHAGELEALQALMELG 445 Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 ++ LKD G ++H AAR G + LL DVN D +G PL LA + H + Sbjct: 446 SDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIR 505 Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGA 164 L K A + ++ K D +L RL R ++ L QA G GA Sbjct: 506 LLRKAGAC-LSPQDLK-DAGTELCRLASRADMEGL-QAWGQAGA 546 >4OAU-C nrPDB Length = 699 Score = 43.1 bits (100), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 42/132 (31%), Positives = 60/132 (45%), Gaps = 2/132 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFG-RTALQ-VMKLGNPEIARRLLLRGANPDLK 66 L A D++ + LL+ NVN Q G T L +++ +I LL GA+P L+ Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 + G AA AG + L+ L ADVN D G AA G ++ ++FL K Sbjct: 69 KKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 128 Query: 127 ASNVGHRNHKGD 138 A+ R K D Sbjct: 129 ANVNLRRKTKED 140 >5U0K-A nrPDB Length = 141 Score = 42.4 bits (98), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 26/81 (32%), Positives = 42/81 (51%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 AA +G + L+ D+ +D + LH+AA EGH+ VV+FL++ N ++ Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRW 91 Query: 137 GDTACDLARLYGRNEVVSLMQ 157 G+ D A + EVV L+Q Sbjct: 92 GNIPLDDAVQFNHLEVVKLLQ 112 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 2/107 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLL-LRGANPDLK 66 L AA GD+ L + +++ ++ RTAL V G+ E+ + L+ NP K Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKE 113 DR G + DA + L+ ++ L ++Q + + + +KE Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDYQDSYTLSETQAEAAAEALSKE 135 >4OT9-A nrPDB Length = 359 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 40/120 (33%), Positives = 54/120 (45%), Gaps = 6/120 (5%) Query: 48 GNPEIARRLLLRGAN--PDL---KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE 102 G PE+ R LL GA P L D G +H A RA + L L++ A+V + + Sbjct: 167 GAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQ 226 Query: 103 G-NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 G LHLA + L +V LV +NV R G+T LA G + L+ GA Sbjct: 227 GGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGA 286 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 11/138 (7%) Query: 18 LEQLTSLLQNNVN---VNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLKDRTGFAV 73 +EQ+ ++ + + VN N +T L + + G + LL GA+P L DR G + Sbjct: 98 IEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSA 157 Query: 74 IHDAAR--AGFLDTLQTLLEFQAD-----VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 +H A R AG + L+ LL+ A +++ D EG P+HLA + ++ LV Sbjct: 158 MHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSG 217 Query: 127 ASNVGHRNHKGDTACDLA 144 A G TA LA Sbjct: 218 AEVEATERQGGRTALHLA 235 Score = 35.8 bits (81), Expect = 0.008, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVK--HTASNVG---HRNHKGDTACDLARLYGRN 150 + +D G+ PLHLA G V+E +V H A ++G NH T LA + G+ Sbjct: 75 LTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQT 134 Query: 151 EVVSLMQANGAGGA 164 VVS + GA A Sbjct: 135 SVVSFLLRVGADPA 148 >5UQE-A nrPDB Length = 520 Score = 41.6 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 41/81 (50%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++ Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483 Query: 137 GDTACDLARLYGRNEVVSLMQ 157 +T D A +G ++V ++Q Sbjct: 484 NNTPMDEALHFGHHDVFKILQ 504 Score = 30.0 bits (66), Expect = 0.57, Method: Composition-based stats. Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 2/95 (2%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLKDRT 69 AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP KDR Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483 Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104 + +A G D + L E+Q + + N Sbjct: 484 NNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 518 >5U0J-A nrPDB Length = 140 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 41/81 (50%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++ Sbjct: 31 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 90 Query: 137 GDTACDLARLYGRNEVVSLMQ 157 +T D A +G ++V ++Q Sbjct: 91 NNTPMDEALHFGHHDVFKILQ 111 Score = 30.4 bits (67), Expect = 0.39, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLL-LRGANPDLK 66 L AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP K Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104 DR + +A G D + L E+Q + + N Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDN 125 >6EMK-G nrPDB Length = 426 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 8/120 (6%) Query: 48 GNPEIARRLLLRGANPDL----KDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--IEDN 101 GN I +RLL R NPDL G++ +H A+ G L++ D + I+ Sbjct: 16 GNLLIVKRLLRR--NPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTF 73 Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 +GN +HLA +GH + + L++ + HR G +A + + +SL+ GA Sbjct: 74 KGNTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGA 133 Score = 33.1 bits (74), Expect = 0.055, Method: Compositional matrix adjust. Identities = 16/54 (29%), Positives = 27/54 (50%) Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 G A IH A + L L+ AD+ + D G+ PLH+ + G + ++ L+ Sbjct: 109 GRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLL 162 >5D68-A nrPDB Length = 486 Score = 38.5 bits (88), Expect = 0.001, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 50/98 (51%), Gaps = 1/98 (1%) Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLP 106 G+ E+ RLL + + D +A IH A G ++ + LLE + + N+ + + + P Sbjct: 49 GDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 108 Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLA 144 LH AA GH +V+ L+ H ++ + +G + ++ Sbjct: 109 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 146 Score = 35.8 bits (81), Expect = 0.010, Method: Compositional matrix adjust. Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 3/105 (2%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRG-ANPDLK 66 L +A GD E L+ LL +VN + + G E R LL +G NP+L Sbjct: 42 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 101 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLA 110 + + +H AA G + +Q LL + D +I D +G PL++ Sbjct: 102 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 146 >3LJN-A nrPDB Length = 364 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 18/63 (28%), Positives = 34/63 (53%) Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 D ++ G + +H A + D +E DVN+EDNE +PL+L+ + + + + L+ Sbjct: 205 DYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELL 264 Query: 124 KHT 126 + T Sbjct: 265 QKT 267 Score = 32.7 bits (73), Expect = 0.070, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107 G + RRL+ G +P +++R G +H A + G +DT + L ++ G P+ Sbjct: 31 GQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVHSLW--HGQKPI 88 Query: 108 HLAAKEGHLRVVEFLVK 124 HLA +V LV+ Sbjct: 89 HLAVMANKTDLVVALVE 105 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 18/49 (36%), Positives = 26/49 (53%) Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122 IH AAR G D ++ L+E I++ G LHLA K G + ++L Sbjct: 24 IHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYL 72 >2KXP-C nrPDB Length = 118 Score = 35.0 bits (79), Expect = 0.017, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 42/92 (45%) Query: 39 RTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI 98 + + +K G+ + + + +G + + G +H AA G L+ L+ LL AD+N Sbjct: 4 KEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINA 63 Query: 99 EDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 D PL A EGH+ V+ L+ A Sbjct: 64 PDKHHITPLLSAVYEGHVSCVKLLLSKGADKT 95 Score = 32.7 bits (73), Expect = 0.072, Method: Compositional matrix adjust. Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 1/98 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDL 65 E A GDL+++ + +VN GR L G EI LLL+GA+ + Sbjct: 4 KEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINA 63 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103 D+ + A G + ++ LL AD ++ +G Sbjct: 64 PDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDG 101 Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust. Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 5/87 (5%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS-NVGHRNH 135 A + G LD ++ + DVN G PLH AA G L ++EFL+ A N ++H Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68 Query: 136 KGDTACDLARLY-GRNEVVSLMQANGA 161 L+ +Y G V L+ + GA Sbjct: 69 ITPL---LSAVYEGHVSCVKLLLSKGA 92 >3ZKJ-A nrPDB Length = 261 Score = 33.9 bits (76), Expect = 0.032, Method: Compositional matrix adjust. Identities = 21/59 (35%), Positives = 32/59 (54%) Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127 + ++ +H+AA G +L+ L+ VNI + PLH A GHL V+ L+KH A Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGA 60 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 27/108 (25%), Positives = 45/108 (41%), Gaps = 1/108 (0%) Query: 5 WGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 W L +A G + + LLQ+ +V ++ + + G+ E L+ G N D Sbjct: 69 WHTPLFNACVSGSWDCVNLLLQHGASVQPESDLASPIHEAARRGHVECVNSLIAYGGNID 128 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAK 112 K ++ A ++ LLE ADVN + + PLH A+ Sbjct: 129 HKISHLGTPLYLACENQQRACVKKLLESGADVNQGKGQDS-PLHAVAR 175 Score = 30.0 bits (66), Expect = 0.53, Method: Compositional matrix adjust. Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 4/120 (3%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDL 65 + L A G L + LL++ VN T L G+ + LL GA+ + Sbjct: 38 SPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGAS--V 95 Query: 66 KDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 + + A IH+AAR G ++ + +L+ + +++ + + PL+LA + V+ L++ Sbjct: 96 QPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLE 155 >4BSZ-B nrPDB Length = 202 Score = 33.5 bits (75), Expect = 0.045, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 14/93 (15%) Query: 78 ARAGFLDTLQ----TLLEFQADVNIEDNEGN-LPLHLAAKEGHLRVVEFLVKHTA----- 127 ARAG LD+L+ TL+ + +++E + LH+AA GH+ V ++++ + Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81 Query: 128 ----SNVGHRNHKGDTACDLARLYGRNEVVSLM 156 + V N G+TA A L G+ +VV L+ Sbjct: 82 EDLKAFVNEVNKTGNTALHWASLNGKLDVVKLL 114 Score = 31.2 bits (69), Expect = 0.22, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 10/89 (11%) Query: 74 IHDAARAGFLDTLQTLLE----------FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 +H AA G ++T++ +LE +A VN + GN LH A+ G L VV+ L Sbjct: 56 LHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLC 115 Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEV 152 ++ RN G A A G+ EV Sbjct: 116 DEYEADPFIRNKFGHDAIFEAENSGKEEV 144 >6BOA-A nrPDB Length = 742 Score = 32.0 bits (71), Expect = 0.12, Method: Composition-based stats. Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158 PL LAAK+ ++ + L+K+ V R G+TA +A LY E + LM+A Sbjct: 48 PLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEA 101 >6GYM-3 nrPDB Length = 321 Score = 31.6 bits (70), Expect = 0.19, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 8/68 (11%) Query: 8 ELASAAARGDLEQLTSLLQN----NVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGA- 61 +L ++AR LE+L +L+N N NVN QN + A+ G+ E R L+G+ Sbjct: 217 KLKKSSARRKLEELNRVLKNNPYFNSNVNVQNSRLKDAVPFTPFNGDREAHPRFTLKGSV 276 Query: 62 --NPDLKD 67 +P +KD Sbjct: 277 YNDPFIKD 284 >6E2G-A nrPDB Length = 727 Score = 31.2 bits (69), Expect = 0.24, Method: Composition-based stats. Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158 PL LAAKE +++ + L+K V + G+TA +A LY E + LM+A Sbjct: 48 PLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEA 101 Score = 30.4 bits (67), Expect = 0.36, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 18/88 (20%) Query: 38 GRTALQVMKLG-NPEIARRLLLRGANPDLKDRTGFAVIHD---------------AARAG 81 G+TAL + + N + R LL RGA+ + R +V H AA G Sbjct: 117 GQTALHIAVINQNVNLVRALLARGAS--VSARATGSVFHYRPHNLIYYGEHPLSFAACVG 174 Query: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHL 109 + ++ L+E AD+ +D+ GN LH+ Sbjct: 175 SEEIVRLLIEHGADIRAQDSLGNTVLHI 202 Score = 26.9 bits (58), Expect = 4.2, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 10/88 (11%) Query: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIH----DAARAGFLDTLQTLLEFQADVNIE--- 99 +G+ EI R L+ GA+ +D G V+H + LL + +++ Sbjct: 173 VGSEEIVRLLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDGGDHLKSLE 232 Query: 100 ---DNEGNLPLHLAAKEGHLRVVEFLVK 124 +N+G P LA EG++ + + L++ Sbjct: 233 LVPNNQGLTPFKLAGVEGNIVMFQHLMQ 260 >2ISQ-A nrPDB Length = 320 Score = 31.2 bits (69), Expect = 0.24, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 7/59 (11%) Query: 52 IARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 +A +L + +KDR GF++I DA + G + +++L IE GN + LA Sbjct: 30 VAAKLEMMEPCSSVKDRIGFSMISDAEKKGLIKPGESVL-------IEPTSGNTGVGLA 81 >1DCQ-A nrPDB Length = 278 Score = 31.2 bits (69), Expect = 0.25, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Query: 15 RGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG-ANPDLKDRTGFAV 73 R L + L+QN+ N++ Q G G TAL L + +LLLRG A+ ++ + +G Sbjct: 182 RTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETP 241 Query: 74 IHDAAR 79 + A R Sbjct: 242 LDIAKR 247 >4AEC-A nrPDB Length = 430 Score = 30.8 bits (68), Expect = 0.29, Method: Compositional matrix adjust. Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 7/59 (11%) Query: 52 IARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 IA +L + +KDR G++++ DA + GF+ +++L +E GN + LA Sbjct: 140 IAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVL-------VEPTSGNTGIGLA 191 >3T9K-A nrPDB Length = 390 Score = 30.8 bits (68), Expect = 0.30, Method: Compositional matrix adjust. Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 3/108 (2%) Query: 18 LEQLTSLLQNNVNVNAQNGFGRTALQVMKL--GNPEIARRLLLR-GANPDLKDRTGFAVI 74 L + L + +VN NG A +++ N +A LL+ GAN + D G + Sbjct: 213 LPTMADALAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPL 272 Query: 75 HDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122 H A G L+ AD+ D+EG PL +A + + +V L Sbjct: 273 HHATILGHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLL 320 Score = 30.0 bits (66), Expect = 0.45, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 1/81 (1%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 A A L + LL+ A+VN D+ G PLH A GH + +K A ++G R+ + Sbjct: 242 ATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGA-DLGARDSE 300 Query: 137 GDTACDLARLYGRNEVVSLMQ 157 G +A ++V+L++ Sbjct: 301 GRDPLTIAMETANADIVTLLR 321 Score = 27.3 bits (59), Expect = 3.5, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 1/63 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDLKD 67 L A A L LLQN NVN + GR L LG+ +A L RGA+ +D Sbjct: 239 LIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARD 298 Query: 68 RTG 70 G Sbjct: 299 SEG 301 >2RFA-A nrPDB Length = 232 Score = 30.8 bits (68), Expect = 0.32, Method: Compositional matrix adjust. Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE-VVSLMQA 158 PL LAAKE ++ + L+K V R G+TA +A LY E + LM+A Sbjct: 6 PLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEA 59 Score = 27.7 bits (60), Expect = 2.7, Method: Compositional matrix adjust. Identities = 26/88 (29%), Positives = 41/88 (46%), Gaps = 18/88 (20%) Query: 38 GRTALQVMKLG-NPEIARRLLLRGANPDLKDRTGFAVIHD---------------AARAG 81 G+TAL + + N + R LL RGA+ + R +V H AA G Sbjct: 75 GQTALHIAVINQNVNLVRALLARGAS--VSARATGSVFHYRPHNLIYYGEHPLSFAACVG 132 Query: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHL 109 + ++ L+E AD+ +D+ GN LH+ Sbjct: 133 SEEIVRLLIEHGADIRAQDSLGNTVLHI 160 >4LMA-A nrPDB Length = 326 Score = 30.4 bits (67), Expect = 0.42, Method: Compositional matrix adjust. Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 23/91 (25%) Query: 22 TSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANP--DLKDRTGFAVIHDAAR 79 T L+Q N A+ GR VMKL G NP +KDR G +I+ A + Sbjct: 21 TPLVQLNRIPQAEGCLGRI---VMKL-----------EGMNPAASVKDRIGTHMINSAEK 66 Query: 80 AGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 AG ++ T+L +E GN + LA Sbjct: 67 AGLINPETTVL-------VEPTSGNTGIALA 90 >3LVQ-E nrPDB Length = 497 Score = 30.0 bits (66), Expect = 0.46, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 +GN LH AA ++ L+K A VG N G+TA D+AR E L++ A Sbjct: 206 DGNTALHYAALYNQPDCLKLLLKGRAL-VGTVNEAGETALDIARKKHHKECEELLEQAQA 264 Query: 162 G 162 G Sbjct: 265 G 265 >5WP0-A nrPDB Length = 279 Score = 30.0 bits (66), Expect = 0.54, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Query: 125 HTASNV-GHRNHKGDTACDLARLYGRNE 151 H+A N+ G GD ACDLA L+G N+ Sbjct: 171 HSAENITGFYTKFGDGACDLAPLFGLNK 198 >2B0O-E nrPDB Length = 301 Score = 29.6 bits (65), Expect = 0.69, Method: Compositional matrix adjust. Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 1/61 (1%) Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 +GN LH AA ++ L+K A VG N G+TA D+AR E L++ A Sbjct: 225 DGNTALHYAALYNQPDCLKLLLKGRAL-VGTVNEAGETALDIARKKHHKECEELLEQAQA 283 Query: 162 G 162 G Sbjct: 284 G 284 >6DMR-A nrPDB Length = 730 Score = 29.6 bits (65), Expect = 0.70, Method: Composition-based stats. Identities = 33/121 (27%), Positives = 53/121 (43%), Gaps = 21/121 (17%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGF-----GRTALQVMKLG-NPEIARRLLLRGAN 62 L AA +LE T L++ + + G+TAL + + N + R LL RGA+ Sbjct: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142 Query: 63 PDLKDRTGFAV--------------IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLH 108 + TG A + AA G + ++ L+E AD+ +D+ GN LH Sbjct: 143 VSAR-ATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLH 201 Query: 109 L 109 + Sbjct: 202 I 202 >6CUD-A nrPDB Length = 806 Score = 29.6 bits (65), Expect = 0.73, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 7/81 (8%) Query: 51 EIARRLLLRGANPDLKDRTGFAVIH-----DAARAGFLDTLQTLLEFQADVNIE--DNEG 103 E RR +RG DR DAA G + ++ +LE +N+ D G Sbjct: 3 EKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMG 62 Query: 104 NLPLHLAAKEGHLRVVEFLVK 124 L LA HL V E L+K Sbjct: 63 QNALQLAVGNEHLEVTELLLK 83 >3Q4G-A nrPDB Length = 279 Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%) Query: 125 HTASNV-GHRNHKGDTACDLARLYGRNE 151 H+A N+ G GD ACDLA L+G N+ Sbjct: 171 HSAENITGFYTKFGDGACDLAPLFGLNK 198 >1W5T-A nrPDB Length = 412 Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust. Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 12/98 (12%) Query: 19 EQLTSLLQNNVNVNAQNGFGRT----------ALQVMKLGNPEIARRLLLRGANPDLKDR 68 E L +LL+ + + +++G R AL M+ P++ ++ + P K R Sbjct: 159 EDLYTLLRVHEEIPSRDGVNRIGFLLVASDVRALSYMREKIPQVESQIGFKLHLPAYKSR 218 Query: 69 TGFAVIHDAARAGFLDTLQTL--LEFQADVNIEDNEGN 104 + ++ A G DT+ LE +DV ED G+ Sbjct: 219 ELYTILEQRAELGLRDTVWEPRHLELISDVYGEDKGGD 256 >6CV9-A nrPDB Length = 842 Score = 29.3 bits (64), Expect = 0.88, Method: Composition-based stats. Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 3/59 (5%) Query: 76 DAARAGFLDTLQTLLE--FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV-KHTASNVG 131 DAA G + ++ +LE +VN D G L LA HL + E L+ K S VG Sbjct: 15 DAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73 Score = 26.9 bits (58), Expect = 4.6, Method: Composition-based stats. Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 7/94 (7%) Query: 42 LQVMKLGNPEIARRLL--LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 L + GN + R++L N + D G + A L+ + LL+ + + Sbjct: 14 LDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 D L LA +G++R+VE ++ H A G R Sbjct: 74 D-----ALLLAISKGYVRIVEAILNHPAFAEGKR 102 >1XLT-A nrPDB Length = 384 Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 20/48 (41%), Gaps = 8/48 (16%) Query: 103 GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN 150 GN PL K +VKH VGH N A D + L+ +N Sbjct: 299 GNCPLSEPGK--------IVVKHGVKIVGHTNVPSRVAADASPLFAKN 338 >4QJ1-A nrPDB Length = 361 Score = 28.5 bits (62), Expect = 1.5, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 7/67 (10%) Query: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLP 106 +G EI R LL A D+ ++ D+A L+ ++TL E ++ +NI+ GN+ Sbjct: 102 IGVNEIERAKLLVEAGVDV-------IVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVV 154 Query: 107 LHLAAKE 113 A KE Sbjct: 155 TEEATKE 161 >6DJS-A nrPDB Length = 676 Score = 28.5 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 7/81 (8%) Query: 51 EIARRLLLRGANPDLKDRTGFAVIH-----DAARAGFLDTLQTLLEFQADVNIE--DNEG 103 E RR +RG DR DAA G + ++ +LE +N+ D G Sbjct: 20 EKGRRQAVRGPAFMFNDRGTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMG 79 Query: 104 NLPLHLAAKEGHLRVVEFLVK 124 L LA HL V E L+K Sbjct: 80 QNALQLAVGNEHLEVTELLLK 100 >3T4P-A nrPDB Length = 334 Score = 28.5 bits (62), Expect = 1.6, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 13/100 (13%) Query: 26 QNNVNVNAQNGFGRT-ALQVMKLGNPEIARRLLLRGANP--DLKDRTGFAVIHDAARAGF 82 NV + G+T AL + KL N + L + NP +KDR GFA+ A + G Sbjct: 8 SKNVAQSIDQLIGQTPALYLNKLNNTKAKVVLKMECENPMASVKDRLGFAIYDKAEKEGK 67 Query: 83 LDTLQTLLEFQADVNIEDNEGNLPL---HLAAKEGHLRVV 119 L ++++ +E + GN + HL A G+ ++ Sbjct: 68 LIPGKSIV-------VESSSGNTGVSLAHLGAIRGYKVII 100 >3FFS-A nrPDB Length = 400 Score = 28.1 bits (61), Expect = 1.7, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 7/67 (10%) Query: 47 LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLP 106 +G EI R LL A D+ ++ D+A L+ ++TL E ++ +NI+ GN+ Sbjct: 141 IGVNEIERAKLLVEAGVDV-------IVLDSAHGHSLNIIRTLKEIKSKMNIDVIVGNVV 193 Query: 107 LHLAAKE 113 A KE Sbjct: 194 TEEATKE 200 >2NYJ-A nrPDB Length = 273 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 25/39 (64%), Gaps = 2/39 (5%) Query: 103 GNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDT 139 G LPL LAA L +V+FL++++ +++ R+ G+T Sbjct: 148 GELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNT 186 >5IRX-A nrPDB Length = 636 Score = 28.1 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 25/39 (64%), Gaps = 2/39 (5%) Query: 103 GNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDT 139 G LPL LAA L +V+FL++++ +++ R+ G+T Sbjct: 143 GELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNT 181 >4LMB-A nrPDB Length = 322 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 9/55 (16%) Query: 58 LRGANP--DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 L NP +KDR G +++ DA AG + +T+L +E GN + LA Sbjct: 43 LESMNPAASVKDRIGVSMVEDAEAAGLIHPDKTIL-------VEPTSGNTGIALA 90 >4LG1-A nrPDB Length = 224 Score = 27.3 bits (59), Expect = 3.1, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 17 DLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN 49 DLE+L LL+ N+N+N G +V+K G Sbjct: 91 DLEELQDLLKMNINMNKHLVTGSVQAKVLKWGE 123 >6ED3-A nrPDB Length = 848 Score = 26.9 bits (58), Expect = 4.6, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 48 GNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLD---TLQTLLEFQADVNIEDNEGN 104 G+ ++A+ L GA+P R F + +AR + T Q L ++ D+ EG Sbjct: 118 GDSDVAKLLTGHGASPQAL-REAFVKVRGSARVTSPEPEATYQALQKYSTDLTARAREGK 176 Query: 105 LPLHLAAKEGHLRVVEFLVKHTASN 129 L + RVV+ L + T +N Sbjct: 177 LDPVIGRDNEIRRVVQVLSRRTKNN 201 >6DVZ-A nrPDB Length = 791 Score = 26.9 bits (58), Expect = 4.8, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 16/102 (15%) Query: 37 FGRTALQVMKLGN-PEIARRLLLRGANPDL--KDRTGFAVIHD--------AARAGFLDT 85 FG T L + N PEI + LL+ D+ +D G ++H + F+ Sbjct: 261 FGETPLALAACTNQPEIVQ-LLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKR 319 Query: 86 LQTLLEFQAD----VNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 + ++ ++ + +N+G PL LAAK G ++++++ Sbjct: 320 MYDMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYIL 361 >5XE7-A nrPDB Length = 312 Score = 26.6 bits (57), Expect = 5.2, Method: Compositional matrix adjust. Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNA-QNGFGRTALQVMKLGNPEIARRLL 57 L +A A GDL+ + SLL +V NG TA++ ++ G+ ++ R +L Sbjct: 184 LMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVR-GSDKVVRFIL 232 >3AUJ-A nrPDB Length = 554 Score = 26.2 bits (56), Expect = 7.0, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQ 93 K+R G V+ A+ GF D Q +L Q Sbjct: 466 KNRNGLEVVKALAQGGFTDVAQDMLNIQ 493 >4XD0-A nrPDB Length = 417 Score = 26.2 bits (56), Expect = 7.7, Method: Compositional matrix adjust. Identities = 26/121 (21%), Positives = 54/121 (44%), Gaps = 5/121 (4%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65 +E+ +A E ++ LL+ + +N G + + + GN ++ L+ +G N + Sbjct: 293 DEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNIND 352 Query: 66 KDRTGFAV---IHDAA-RAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 ++ G V D R+G L+ L+ D+ ++DNEG K ++ + F Sbjct: 353 RNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNF 412 Query: 122 L 122 + Sbjct: 413 M 413 >2RON-A nrPDB Length = 242 Score = 26.2 bits (56), Expect = 8.1, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 19/36 (52%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGF 37 AEP G+ +A DLE+LT L + +N+ F Sbjct: 45 AEPPGHGTNQTSAIEDLEELTDLYKQELNLRPDRPF 80 >6BO5-A nrPDB Length = 695 Score = 25.8 bits (55), Expect = 8.3, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 19/31 (61%) Query: 98 IEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128 I +++G PL LAAKEG + + +++ S Sbjct: 250 ISNHQGLTPLKLAAKEGKIEIFRHILQREFS 280 >5HI9-A nrPDB Length = 770 Score = 25.8 bits (55), Expect = 8.3, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 19/31 (61%) Query: 98 IEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128 I +++G PL LAAKEG + + +++ S Sbjct: 290 ISNHQGLTPLKLAAKEGKIEIFRHILQREFS 320 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1G3N-B nrPDB 204 2e-53 5AQB-A nrPDB 197 1e-51 5AQ9-A nrPDB 197 2e-51 5MIO-C nrPDB 187 3e-48 6MWQ-A nrPDB 183 3e-47 5AQA-A nrPDB 182 7e-47 6FES-A nrPDB 179 4e-46 5H76-A nrPDB 178 1e-45 5AQ7-A nrPDB 166 3e-42 1BLX-B nrPDB 158 1e-39 1BD8-A nrPDB 154 2e-38 6BY9-A nrPDB 153 3e-38 3B7B-A nrPDB 150 2e-37 4Z68-A nrPDB 150 3e-37 5CBO-A nrPDB 150 4e-37 4OAU-C nrPDB 145 7e-36 5JHQ-A nrPDB 142 6e-35 3EU9-A nrPDB 142 8e-35 5HKP-A nrPDB 141 1e-34 5GP7-A nrPDB 140 2e-34 4NIK-A nrPDB 139 6e-34 2DWZ-A nrPDB 138 7e-34 4O1O-A nrPDB 130 3e-31 6AUN-A nrPDB 130 3e-31 1WG0-A nrPDB 128 1e-30 2A5E-A nrPDB 126 3e-30 6EMK-G nrPDB 124 2e-29 5ET1-A nrPDB 122 7e-29 4OT9-A nrPDB 122 8e-29 5DND-A nrPDB 121 2e-28 1D9S-A nrPDB 117 3e-27 5D68-A nrPDB 111 1e-25 3EHQ-A nrPDB 106 6e-24 5UQE-A nrPDB 98 2e-21 3UI2-A nrPDB 96 7e-21 3DEO-A nrPDB 95 2e-20 5U0K-A nrPDB 93 4e-20 5U0J-A nrPDB 92 8e-20 Sequences not found previously or not previously below threshold: 3ZKJ-A nrPDB 98 2e-21 2KXP-C nrPDB 88 2e-18 6E2G-A nrPDB 84 2e-17 3LJN-A nrPDB 80 5e-16 6DMR-A nrPDB 76 6e-15 3T9K-A nrPDB 76 7e-15 2RFA-A nrPDB 76 9e-15 6BOA-A nrPDB 75 2e-14 4BSZ-B nrPDB 73 8e-14 3LVQ-E nrPDB 65 1e-11 6DVZ-A nrPDB 65 2e-11 4N5Q-A nrPDB 64 3e-11 2B0O-E nrPDB 63 7e-11 1DCQ-A nrPDB 62 1e-10 6CUD-A nrPDB 60 4e-10 5IRX-A nrPDB 60 4e-10 6CV9-A nrPDB 60 5e-10 6DJS-A nrPDB 60 6e-10 6OO7-A nrPDB 59 1e-09 2NYJ-A nrPDB 58 1e-09 5UIL-A nrPDB 58 1e-09 5AN8-A nrPDB 58 2e-09 6BO5-A nrPDB 56 7e-09 5HI9-A nrPDB 56 7e-09 6G1K-A nrPDB 53 4e-08 6C8G-A nrPDB 53 5e-08 6BBJ-A nrPDB 53 5e-08 2ETB-A nrPDB 53 6e-08 2F37-A nrPDB 52 1e-07 4XD0-A nrPDB 51 2e-07 3W9G-A nrPDB 51 2e-07 6MHW-A nrPDB 48 2e-06 4DX2-A nrPDB 48 2e-06 5Z96-A nrPDB 46 9e-06 4CJ9-A nrPDB 31 0.29 3LJQ-A nrPDB 31 0.36 4WVX-A nrPDB 29 1.3 2DI3-A nrPDB 28 2.2 1HXH-A nrPDB 28 2.2 5Z56-q nrPDB 27 3.4 4LG8-A nrPDB 27 3.4 5XE7-A nrPDB 27 3.7 1JI6-A nrPDB 26 5.6 1KKT-A nrPDB 26 5.7 >1G3N-B nrPDB Length = 168 Score = 204 bits (519), Expect = 2e-53, Method: Composition-based stats. Identities = 168/168 (100%), Positives = 168/168 (100%) Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG Sbjct: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60 Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE Sbjct: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ Sbjct: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 >5AQB-A nrPDB Length = 428 Score = 197 bits (502), Expect = 1e-51, Method: Composition-based stats. Identities = 56/155 (36%), Positives = 85/155 (54%), Gaps = 1/155 (0%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65 G +L AA G ++ L+ N +VNA + G T L + G+ EI LL GA+ + Sbjct: 15 GKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVNA 74 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 D G+ +H AA +G L+ ++ LL++ ADVN +D G PLHLAA GHL +VE L+K+ Sbjct: 75 ADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKN 134 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 A +V ++ G T DLA G ++ ++ Sbjct: 135 GA-DVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAA 168 Score = 148 bits (374), Expect = 9e-37, Method: Composition-based stats. Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 2/126 (1%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 G+ L+ + G + R L+ GA+ + D G+ +H AA G L+ ++ LL+ AD Sbjct: 13 DLGKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAW-GHLEIVECLLKNGAD 71 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 VN D +G PLHLAA GHL +VE L+K+ A +V + G T LA ++G E+V + Sbjct: 72 VNAADIDGYTPLHLAAFSGHLEIVEVLLKYGA-DVNADDQAGFTPLHLAAIFGHLEIVEV 130 Query: 156 MQANGA 161 + NGA Sbjct: 131 LLKNGA 136 Score = 90.8 bits (224), Expect = 3e-19, Method: Composition-based stats. Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 5/112 (4%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA G LE + LL+ +VNA + G T L + G+ EI LL GA+ + + Sbjct: 82 PLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQ 141 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRV 118 D+ G A G D + L + V ++D L A+ G++ + Sbjct: 142 DKFGKTPRDLAIDNGNEDIAEVLGKAATLVKVKDAADQ----LGARVGYIEL 189 >5AQ9-A nrPDB Length = 422 Score = 197 bits (501), Expect = 2e-51, Method: Composition-based stats. Identities = 62/158 (39%), Positives = 90/158 (56%), Gaps = 2/158 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 134 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 H A +V ++ G T DLA G ++V +L+Q A Sbjct: 135 HGA-DVNAQDKFGKTPFDLADDNGNDDVGTLLQVAAAA 171 Score = 158 bits (401), Expect = 7e-40, Method: Composition-based stats. Identities = 47/126 (37%), Positives = 70/126 (55%), Gaps = 1/126 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ AD Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 72 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 V+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V + Sbjct: 73 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYLEIVEV 131 Query: 156 MQANGA 161 + +GA Sbjct: 132 LLKHGA 137 Score = 137 bits (346), Expect = 2e-33, Method: Composition-based stats. Identities = 43/123 (34%), Positives = 64/123 (52%), Gaps = 1/123 (0%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDLK 66 L AA G LE + LL++ +V+A + FG T L + G+ EI LL GA+ + Sbjct: 50 PLHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAM 109 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D G +H AA+ G+L+ ++ LL+ ADVN +D G P LA G+ V L Sbjct: 110 DSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAA 169 Query: 127 ASN 129 A++ Sbjct: 170 AAD 172 Score = 84.2 bits (207), Expect = 3e-17, Method: Composition-based stats. Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 1/103 (0%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA G LE + LL+N +VNA + G T L + G EI LL GA+ + + Sbjct: 83 PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGADVNAQ 142 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHL 109 D+ G A G D L A + G + L L Sbjct: 143 DKFGKTPFDLADDNGNDDVGTLLQVAAAADQLGARVGYIELDL 185 >5MIO-C nrPDB Length = 573 Score = 187 bits (474), Expect = 3e-48, Method: Composition-based stats. Identities = 56/154 (36%), Positives = 83/154 (53%), Gaps = 2/154 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ Sbjct: 411 GKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVS 470 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G +H AA G L+ ++ LL+ ADVN D G+ PL LAA GHL++VE L+K Sbjct: 471 ASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLK 530 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158 H A +V ++ G TA D + G ++ ++Q Sbjct: 531 HGA-DVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563 Score = 162 bits (411), Expect = 6e-41, Method: Composition-based stats. Identities = 46/126 (36%), Positives = 70/126 (55%), Gaps = 1/126 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 G+ L+ + G + R L+ GA+ + D +G +H AA G L+ ++ LL+ AD Sbjct: 409 DLGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGAD 468 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 V+ D G+ PLHLAA GHL +VE L+KH A +V + GDT LA + G ++V Sbjct: 469 VSASDLMGSTPLHLAALIGHLEIVEVLLKHGA-DVNAVDTWGDTPLRLAAVMGHLKIVEA 527 Query: 156 MQANGA 161 + +GA Sbjct: 528 LLKHGA 533 Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA G LE + LL++ +VNA + +G T L++ +G+ +I LL GA+ + + Sbjct: 479 PLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQ 538 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQ 93 D+ G + G D + L + Sbjct: 539 DKFGKTAYDTSIDNGSEDLAEILQKLN 565 >6MWQ-A nrPDB Length = 493 Score = 183 bits (465), Expect = 3e-47, Method: Composition-based stats. Identities = 58/154 (37%), Positives = 88/154 (57%), Gaps = 2/154 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + FG T L + + G+ EI LL GA+ + Sbjct: 6 GKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVN 65 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G +H AA AG L+ ++ LL++ ADVN D G PLHL A +GHL +VE L+K Sbjct: 66 AADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLLK 125 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158 H A +V ++ G TA D++ G ++ ++Q Sbjct: 126 HGA-DVNAQDKFGKTAFDISIDNGNEDLAEILQK 158 Score = 157 bits (397), Expect = 2e-39, Method: Composition-based stats. Identities = 46/126 (36%), Positives = 69/126 (54%), Gaps = 1/126 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 G+ L+ + G + R L+ GA+ + DR G +H AA+ G L+ ++ LL+ AD Sbjct: 4 DLGKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGAD 63 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 VN D G PLHLAA GHL +VE L+K+ A +V + G T L + G E+V + Sbjct: 64 VNAADLWGQTPLHLAATAGHLEIVEVLLKYGA-DVNALDLIGKTPLHLTAIDGHLEIVEV 122 Query: 156 MQANGA 161 + +GA Sbjct: 123 LLKHGA 128 Score = 134 bits (338), Expect = 2e-32, Method: Composition-based stats. Identities = 43/127 (33%), Positives = 65/127 (51%), Gaps = 1/127 (0%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA RG LE + LL+ +VNA + +G+T L + G+ EI LL GA+ + Sbjct: 41 PLHLAAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNAL 100 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D G +H A G L+ ++ LL+ ADVN +D G ++ G+ + E L K Sbjct: 101 DLIGKTPLHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLN 160 Query: 127 ASNVGHR 133 S++ HR Sbjct: 161 LSDIAHR 167 >5AQA-A nrPDB Length = 418 Score = 182 bits (462), Expect = 7e-47, Method: Composition-based stats. Identities = 56/155 (36%), Positives = 83/155 (53%), Gaps = 2/155 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+ +VE L+K Sbjct: 75 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLLK 134 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 A +V ++ G LA G E+ + + A Sbjct: 135 AGA-DVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 157 bits (398), Expect = 2e-39, Method: Composition-based stats. Identities = 47/126 (37%), Positives = 69/126 (54%), Gaps = 1/126 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ AD Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 72 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 V+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V + Sbjct: 73 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYKEIVEV 131 Query: 156 MQANGA 161 + GA Sbjct: 132 LLKAGA 137 >6FES-A nrPDB Length = 367 Score = 179 bits (455), Expect = 4e-46, Method: Composition-based stats. Identities = 55/151 (36%), Positives = 76/151 (50%), Gaps = 2/151 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ LL N +VN + G T L + G+ I LL GA+ + Sbjct: 7 GKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 66 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G +H AA G L+ ++ LL+ A VN D G PLHLAA GH +VE L+K Sbjct: 67 ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLLK 126 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 + A + ++ G T DLAR G V L Sbjct: 127 NGA-DARAQDKFGKTPEDLARDNGYESVARL 156 Score = 161 bits (408), Expect = 1e-40, Method: Composition-based stats. Identities = 49/126 (38%), Positives = 69/126 (54%), Gaps = 1/126 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ AD Sbjct: 5 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 64 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 VN D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V + Sbjct: 65 VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-VNATDVIGTAPLHLAAMWGHEEIVEV 123 Query: 156 MQANGA 161 + NGA Sbjct: 124 LLKNGA 129 Score = 106 bits (266), Expect = 4e-24, Method: Composition-based stats. Identities = 41/89 (46%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 + +AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V Sbjct: 10 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNAN 68 Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGAG 162 + +G T LA G E+V ++ NGAG Sbjct: 69 DERGHTPLHLAAYTGHLEIVEVLLKNGAG 97 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 24/52 (46%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLR 59 L AA G E + LL+N + AQ+ FG+T + + E RL + Sbjct: 108 PLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARLARK 159 >5H76-A nrPDB Length = 201 Score = 178 bits (452), Expect = 1e-45, Method: Composition-based stats. Identities = 57/152 (37%), Positives = 86/152 (56%), Gaps = 3/152 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + G T L + G+ EI LL GA+ D Sbjct: 7 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 66 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G+ +H AA G L+ ++ LL+ ADVN D++G PLHLAAK G+L +VE L+K Sbjct: 67 ASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLK 126 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 H A V ++ G TA D++ G ++ ++ Sbjct: 127 HGA--VNAQDKFGKTAFDISIDNGNEDLAQIL 156 Score = 151 bits (382), Expect = 1e-37, Method: Composition-based stats. Identities = 48/131 (36%), Positives = 72/131 (54%), Gaps = 1/131 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 GR L+ + G + R L+ GA+ + D TG +H AA +G L+ ++ LL+ AD Sbjct: 5 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGAD 64 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 V+ D G PLHLAA GHL +VE L+K+ A +V + G T LA +G E+V + Sbjct: 65 VDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA-DVNAMDSDGMTPLHLAAKWGYLEIVEV 123 Query: 156 MQANGAGGATN 166 + +GA A + Sbjct: 124 LLKHGAVNAQD 134 Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 2/86 (2%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA G LE + LL+N +VNA + G T L + G EI LL GA + + Sbjct: 75 PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLLKHGA-VNAQ 133 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92 D+ G + G D Q L + Sbjct: 134 DKFGKTAFDISIDNGNEDLAQILAFY 159 >5AQ7-A nrPDB Length = 418 Score = 166 bits (421), Expect = 3e-42, Method: Composition-based stats. Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 2/155 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ LL N +VN + G T L + G+ I LL GA+ + Sbjct: 15 GKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 74 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D G +H AA G L+ ++ LL+ A VN D G PLHLAA G+ +VE L+K Sbjct: 75 ANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLLK 134 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 A +V ++ G LA G E+ + + A Sbjct: 135 AGA-DVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 152 bits (383), Expect = 8e-38, Method: Composition-based stats. Identities = 48/126 (38%), Positives = 68/126 (53%), Gaps = 1/126 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 G+ L+ + G + R LL GA+ + D TGF +H AA G L ++ LL+ AD Sbjct: 13 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGAD 72 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 VN D G+ PLHLAA GHL +VE L+K+ A V + G LA ++G E+V + Sbjct: 73 VNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG-VNATDVIGTAPLHLAAMWGYKEIVEV 131 Query: 156 MQANGA 161 + GA Sbjct: 132 LLKAGA 137 Score = 101 bits (253), Expect = 1e-22, Method: Composition-based stats. Identities = 41/89 (46%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 + +AARAG D ++ LL ADVN D G PLHLAA EGHL +VE L+K+ A +V Sbjct: 18 LLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGA-DVNAN 76 Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGAG 162 + +G T LA G E+V ++ NGAG Sbjct: 77 DERGHTPLHLAAYTGHLEIVEVLLKNGAG 105 >1BLX-B nrPDB Length = 166 Score = 158 bits (400), Expect = 1e-39, Method: Composition-based stats. Identities = 72/155 (46%), Positives = 106/155 (68%), Gaps = 3/155 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+P +A LL +GA+P+ Sbjct: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPN 68 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 ++D +G + +HDAAR GFLDTL+ L+E ADVN D+ G+LP+HLA +EGH VV FL Sbjct: 69 VQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL-- 126 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 S++ HR+ G T +LAR G ++ ++Q + Sbjct: 127 APESDLHHRDASGLTPLELARQRGAQNLMDILQGH 161 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 34/86 (39%), Gaps = 3/86 (3%) Query: 77 AARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135 AA G + ++ LL + + + G L + G V L+K AS ++ Sbjct: 15 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSPAVALELLKQGASP-NVQDA 72 Query: 136 KGDTACDLARLYGRNEVVSLMQANGA 161 G + A G + + ++ +GA Sbjct: 73 SGTSPVHDAARTGFLDTLKVLVEHGA 98 >1BD8-A nrPDB Length = 156 Score = 154 bits (390), Expect = 2e-38, Method: Composition-based stats. Identities = 71/155 (45%), Positives = 104/155 (67%), Gaps = 3/155 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 G+ L+ AAARGD++++ LL V+ +A N FG+TALQVM G+ IA LL +GA+P+ Sbjct: 3 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPN 62 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 ++D +G + +HDAAR GFLDTL+ L+E ADVN+ D G LP+HLA +EGH VV FL Sbjct: 63 VQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL-- 120 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 S++ R+ +G T +LA G ++V ++Q + Sbjct: 121 AAESDLHRRDARGLTPLELALQRGAQDLVDILQGH 155 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 34/86 (39%), Gaps = 3/86 (3%) Query: 77 AARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH 135 AA G + ++ LL + + + G L + G + L+K AS ++ Sbjct: 9 AAARGDVQEVRRLLHRELVHPDALNRFGKTALQV-MMFGSTAIALELLKQGASP-NVQDT 66 Query: 136 KGDTACDLARLYGRNEVVSLMQANGA 161 G + A G + + ++ +GA Sbjct: 67 SGTSPVHDAARTGFLDTLKVLVEHGA 92 >6BY9-A nrPDB Length = 328 Score = 153 bits (387), Expect = 3e-38, Method: Composition-based stats. Identities = 44/155 (28%), Positives = 81/155 (52%), Gaps = 5/155 (3%) Query: 9 LASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDLK 66 L AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++ Sbjct: 172 LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIR 231 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D +H AA +G +D + LL + D++ + G+ PLH+AA+E V + Sbjct: 232 DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR- 290 Query: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 S+V +N +G+T A L ++V S +Q + A Sbjct: 291 DSDVTLKNKEGETPLQCASL--NSQVWSALQMSKA 323 Score = 129 bits (324), Expect = 6e-31, Method: Composition-based stats. Identities = 43/158 (27%), Positives = 83/158 (52%), Gaps = 3/158 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQ--NGFGRTALQVMK-LGNPEIARRLLLRGANP 63 +L +A +G+L+++ +L + ++ N + + R+ L G+ +I L+ GAN Sbjct: 69 KQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANI 128 Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 D + +AA L+ ++ L++ A V+ +D EG+ LHLAAK+GH VV++L+ Sbjct: 129 DTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLL 188 Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + +V ++ G T A Y ++V L+ + G+ Sbjct: 189 SNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGS 226 Score = 33.4 bits (75), Expect = 0.048, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 18/44 (40%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN 49 + L AA + + L + +V +N G T LQ L + Sbjct: 269 DSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNS 312 >3B7B-A nrPDB Length = 237 Score = 150 bits (380), Expect = 2e-37, Method: Composition-based stats. Identities = 44/155 (28%), Positives = 81/155 (52%), Gaps = 5/155 (3%) Query: 9 LASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGANPDLK 66 L AA +G E + LL N ++VN Q+ G T + + + ++ + LL +G++ +++ Sbjct: 81 LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIR 140 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D +H AA +G +D + LL + D++ + G+ PLH+AA+E V + Sbjct: 141 DNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR- 199 Query: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 S+V +N +G+T A L ++V S +Q + A Sbjct: 200 DSDVTLKNKEGETPLQCASL--NSQVWSALQMSKA 232 Score = 116 bits (292), Expect = 3e-27, Method: Composition-based stats. Identities = 40/156 (25%), Positives = 75/156 (48%), Gaps = 3/156 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDL 65 + L +AA G ++ L+Q N++ + RT L + + + E + L+ GA D Sbjct: 13 SPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDP 72 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 KD G +H AA+ G + +Q LL DVN +D+ G P+ A + H+ +V+ L+ Sbjct: 73 KDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLS 132 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 S++ R+++ + A G ++ ++ A Sbjct: 133 KG-SDINIRDNEENICLHWAAFSGCVDIAEILLAAK 167 Score = 111 bits (278), Expect = 2e-25, Method: Composition-based stats. Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%) Query: 36 GFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA 94 R+ L G+ +I L+ GAN D + +AA L+ ++ L++ A Sbjct: 9 QNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGA 68 Query: 95 DVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVS 154 V+ +D EG+ LHLAAK+GH VV++L+ + +V ++ G T A Y ++V Sbjct: 69 LVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVK 128 Query: 155 LMQANGA 161 L+ + G+ Sbjct: 129 LLLSKGS 135 Score = 33.0 bits (74), Expect = 0.067, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 18/44 (40%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN 49 + L AA + + L + +V +N G T LQ L + Sbjct: 178 DSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNS 221 Score = 26.8 bits (58), Expect = 4.1, Method: Composition-based stats. Identities = 5/33 (15%), Positives = 11/33 (33%) Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 N + + A G ++ ++ GA Sbjct: 3 NFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGA 35 >4Z68-A nrPDB Length = 155 Score = 150 bits (379), Expect = 3e-37, Method: Composition-based stats. Identities = 44/153 (28%), Positives = 70/153 (45%), Gaps = 4/153 (2%) Query: 6 GNELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANP 63 +L AA GD+E + L +VN G T L N + LL GA+ Sbjct: 4 DRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63 Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 KD+ G +H+A G + + L++ A VN+ D PLH AA +G + + L+ Sbjct: 64 HAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLL 123 Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 +H A + +N G+T DL + G ++ L+ Sbjct: 124 QHGA-DPTKKNRDGNTPLDLVKD-GDTDIQDLL 154 Score = 108 bits (271), Expect = 1e-24, Method: Composition-based stats. Identities = 39/125 (31%), Positives = 59/125 (47%), Gaps = 4/125 (3%) Query: 39 RTALQVMKLGNPEIARRLLLRGANPDLKDRTG--FAVIHDAARAGFLDTLQTLLEFQADV 96 R L+ K G+ E ++L + + +D G +H AA + ++ LL+ ADV Sbjct: 5 RQLLEAAKAGDVETVKKLCTVQS-VNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADV 63 Query: 97 NIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 + +D G +PLH A GH V E LVKH A V + T A G+ E+ L+ Sbjct: 64 HAKDKGGLVPLHNACSYGHYEVAELLVKHGAV-VNVADLWKFTPLHEAAAKGKYEICKLL 122 Query: 157 QANGA 161 +GA Sbjct: 123 LQHGA 127 >5CBO-A nrPDB Length = 176 Score = 150 bits (378), Expect = 4e-37, Method: Composition-based stats. Identities = 44/129 (34%), Positives = 70/129 (54%), Gaps = 1/129 (0%) Query: 36 GFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD 95 G+ L+ G + R L+ GA+ + D G +H AA G + ++ LL++ AD Sbjct: 2 DLGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGAD 61 Query: 96 VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSL 155 VN D G+ PLHLAAK G+L +VE L+K+ A +V ++ G TA D++ G ++ + Sbjct: 62 VNASDATGDTPLHLAAKWGYLGIVEVLLKYGA-DVNAQDKFGKTAFDISIDNGNEDLAEI 120 Query: 156 MQANGAGGA 164 + N A A Sbjct: 121 LCKNKAQQA 129 Score = 135 bits (340), Expect = 9e-33, Method: Composition-based stats. Identities = 42/123 (34%), Positives = 66/123 (53%), Gaps = 1/123 (0%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPD 64 G +L AA G +++ L+ N +VNA + FG T L + G+ EI LL GA+ + Sbjct: 4 GKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVN 63 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 D TG +H AA+ G+L ++ LL++ ADVN +D G ++ G+ + E L K Sbjct: 64 ASDATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEILCK 123 Query: 125 HTA 127 + A Sbjct: 124 NKA 126 >4OAU-C nrPDB Length = 699 Score = 145 bits (367), Expect = 7e-36, Method: Composition-based stats. Identities = 48/160 (30%), Positives = 69/160 (43%), Gaps = 11/160 (6%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFG-RTALQ-VMKLGNPEIARRLLLRGANPDLK 66 L A D++ + LL+ NVN Q G T L +++ +I LL GA+P L+ Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 + G AA AG + L+ L ADVN D G AA G ++ ++FL K Sbjct: 69 KKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 128 Query: 127 ASNVGHRNHK---------GDTACDLARLYGRNEVVSLMQ 157 A+ R K G TA A G EV+ ++ Sbjct: 129 ANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILL 168 Score = 110 bits (276), Expect = 3e-25, Method: Composition-based stats. Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 2/121 (1%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTG-FAVIHDAARAGFLDTLQTLLEFQADVNIED 100 ++ ++ + ++ ++LL GAN + ++ G + +H+A + D ++ LL AD + Sbjct: 10 IKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRK 69 Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 G P LAA G +++++ + A +V + G TA A +YG+ + + + G Sbjct: 70 KNGATPFILAAIAGSVKLLKLFLSKGA-DVNECDFYGFTAFMEAAVYGKVKALKFLYKRG 128 Query: 161 A 161 A Sbjct: 129 A 129 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 37/169 (21%), Positives = 71/169 (42%), Gaps = 15/169 (8%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L +A + + LL++ + + G T + G+ ++ + L +GA+ + Sbjct: 42 PLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNEC 101 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNE----------GNLPLHLAAKEGHL 116 D GF +AA G + L+ L + A+VN+ G L AA++GH+ Sbjct: 102 DFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHV 161 Query: 117 RVVEFLVKHTASNVGHRNHKGDTACDLARL----YGRNEVVSLMQANGA 161 V++ L+ ++V ++ G A A L + L+ +GA Sbjct: 162 EVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGA 210 Score = 106 bits (265), Expect = 4e-24, Method: Composition-based stats. Identities = 47/200 (23%), Positives = 76/200 (38%), Gaps = 49/200 (24%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTA-LQVMKLGNPEIARRLLLRGANPDLKDRT- 69 AA G ++ L L +VN + +G TA ++ G + + L RGAN +L+ +T Sbjct: 79 AAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTK 138 Query: 70 ---------GFAVIHDAARAGFLDTLQ--------------------------------- 87 G + DAA G ++ L+ Sbjct: 139 EDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDV 198 Query: 88 -----TLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142 LL+ ADVN+ G PL LA ++ HL +V+ L++ + + G TA Sbjct: 199 EAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALL 258 Query: 143 LARLYGRNEVVSLMQANGAG 162 LA ++ L+ GA Sbjct: 259 LAVELKLKKIAELLCKRGAS 278 Score = 95.4 bits (236), Expect = 1e-20, Method: Composition-based stats. Identities = 44/160 (27%), Positives = 70/160 (43%), Gaps = 13/160 (8%) Query: 9 LASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTAL-QVMKLGNPEIAR----RLLLRGAN 62 L AA +G +E L LL +VNA + GR AL + + LL GA+ Sbjct: 152 LMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGAD 211 Query: 63 PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA-DVNIEDNEGNLPLHLAAKEGHLRVVEF 121 +++ G + A L +Q LLE + ++N D++G L LA + ++ E Sbjct: 212 VNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAEL 271 Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 L K AS GD R Y + +V ++ ++GA Sbjct: 272 LCKRGAST-----DCGDLVMTARRNYDHS-LVKVLLSHGA 305 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 24/55 (43%) Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 L A + + +V+ L++ A+ G T A R ++V L+ +GA Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGA 63 >5JHQ-A nrPDB Length = 482 Score = 142 bits (359), Expect = 6e-35, Method: Composition-based stats. Identities = 54/170 (31%), Positives = 79/170 (46%), Gaps = 11/170 (6%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGR--TALQ-VMKLGNPEIARRLLLRGANP 63 EL A GD+ ++ L+ + NVNA++ GR + L G ++ LL GAN Sbjct: 17 RELLEACRNGDVSRVKRLV-DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANV 75 Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 +D G +H+A G + + LL AD N DN PLH AA +G + V L+ Sbjct: 76 HARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 135 Query: 124 KHTASNVGHRNHKGDTACDL------ARLYGRNEVVSLMQANGAGGATNL 167 +H A + RN G +A DL A L G + L++A +G L Sbjct: 136 QHGA-DPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKL 184 Score = 141 bits (355), Expect = 1e-34, Method: Composition-based stats. Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%) Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64 +EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+ Sbjct: 170 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 229 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+ Sbjct: 230 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 289 Query: 125 HTASNVGHRNHKGDTACDLA 144 H A H G +A D+A Sbjct: 290 HGADPTLVNCH-GKSAVDMA 308 Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats. Identities = 53/216 (24%), Positives = 82/216 (37%), Gaps = 56/216 (25%) Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLR 59 MA + L AA G + + LLQ NV+A++ G L G+ E+ LL + Sbjct: 45 MAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQ 104 Query: 60 GANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ----------------ADV------- 96 GA+P+ +D + +H+AA G +D LL+ AD Sbjct: 105 GADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLT 164 Query: 97 -------------------------------NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 + D + PLHLAA +R+V+ L++H Sbjct: 165 GEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 224 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 A +V ++ G A YG EV L+ +GA Sbjct: 225 GA-DVHAKDKGGLVPLHNACSYGHYEVTELLLKHGA 259 Score = 120 bits (302), Expect = 2e-28, Method: Composition-based stats. Identities = 52/177 (29%), Positives = 75/177 (42%), Gaps = 25/177 (14%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL---------------------QVMK 46 L AA +G ++ LLQ+ + N +N G++AL + + Sbjct: 118 PLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAAR 177 Query: 47 LGNPEIARRLLLRGANPDLKDRTG--FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104 GN E LL N + G +H AA + +Q LL+ ADV+ +D G Sbjct: 178 SGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGL 236 Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 +PLH A GH V E L+KH A V + T A R EV SL+ ++GA Sbjct: 237 VPLHNACSYGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNRVEVCSLLLSHGA 292 Score = 98.5 bits (244), Expect = 1e-21, Method: Composition-based stats. Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 9/158 (5%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL----GNPEIARRLLLRGA 61 G+ L AA DL ++ L + Q TAL ++ LL +GA Sbjct: 323 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGA 382 Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 N + K++ +H AA D ++ L + A +N D G LH AA GHL+ Sbjct: 383 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRL 442 Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 L+ + S+ + +G T A G V ++ + Sbjct: 443 LLSYG-SDPSIISLQGFT----AAQMGNEAVQQILSES 475 Score = 91.2 bits (225), Expect = 2e-19, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 75/212 (35%), Gaps = 59/212 (27%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGAN---- 62 L +A + G E LL++ VNA + + T L N E+ LL GA+ Sbjct: 238 PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 297 Query: 63 -------------PDLKDR-------------------------------------TGFA 72 P+L++R + Sbjct: 298 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 357 Query: 73 VIHDAARAGFLD---TLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129 +H A + + LL A+VN ++ + PLH+AA+ H V+E L KH A Sbjct: 358 ALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK- 416 Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + + G TA A L G + L+ + G+ Sbjct: 417 MNALDTLGQTALHRAALAGHLQTCRLLLSYGS 448 >3EU9-A nrPDB Length = 240 Score = 142 bits (358), Expect = 8e-35, Method: Composition-based stats. Identities = 41/158 (25%), Positives = 74/158 (46%), Gaps = 4/158 (2%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQV-MKLGNPEIARRLLLRGANPDLK 66 L A +G L + L++ + + +G G + + + + G+ I L+ +G + D+ Sbjct: 79 PLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMM 138 Query: 67 DRTGFAVIHDAARAGF-LDTLQTLLEFQADVNIEDN-EGNLPLHLAAKEGHLRVVEFLVK 124 D+ G + AA +D + LL F VN+ D N LH A G+ V+ L++ Sbjct: 139 DQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLLLE 198 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 A NV +N KG++A DLA+ +++ +Q Sbjct: 199 AGA-NVDAQNIKGESALDLAKQRKNVWMINHLQEARQA 235 Score = 116 bits (290), Expect = 6e-27, Method: Composition-based stats. Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 3/156 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQN-GFGRTALQVM-KLGNPEIARRLLLRGANPDLK 66 L AA ++ + + V+ T L + G+ + +L+ GA+P L Sbjct: 46 LHWAAINNRIDLVKYYISKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLI 105 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGH-LRVVEFLVKH 125 D G + IH AA+ G + L+ DV++ D G PL AA H + L+ Sbjct: 106 DGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTF 165 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 S + +TA A L G V+SL+ GA Sbjct: 166 NVSVNLGDKYHKNTALHWAVLAGNTTVISLLLEAGA 201 Score = 107 bits (267), Expect = 3e-24, Method: Composition-based stats. Identities = 36/153 (23%), Positives = 66/153 (43%), Gaps = 4/153 (2%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD-L 65 ++ A G E+ L++ +V + T L + N ++ + + +GA D L Sbjct: 12 DIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQL 71 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 +H A R G L + L+++ AD ++ D EG +HLAA+ GH +V +L+ Sbjct: 72 GGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAK 131 Query: 126 TASNVGHRNHKGDTACDLARLYGRN-EVVSLMQ 157 +V + G T A + + L+ Sbjct: 132 G-QDVDMMDQNGMTPLMWAAYRTHSVDPTRLLL 163 Score = 84.2 bits (207), Expect = 2e-17, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 59/128 (46%), Gaps = 2/128 (1%) Query: 35 NGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQA 94 + ++ + G E R L+ G + D+ ++H AA +D ++ + A Sbjct: 7 DYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGA 66 Query: 95 DVNIEDNE-GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVV 153 V+ + + PLH A ++GHL +V L+K+ A + + +G + LA +G +V Sbjct: 67 IVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGA-DPSLIDGEGCSCIHLAAQFGHTSIV 125 Query: 154 SLMQANGA 161 + + A G Sbjct: 126 AYLIAKGQ 133 >5HKP-A nrPDB Length = 351 Score = 141 bits (356), Expect = 1e-34, Method: Composition-based stats. Identities = 48/140 (34%), Positives = 68/140 (48%), Gaps = 3/140 (2%) Query: 7 NELASAAARGDLEQLTSLLQN-NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64 +EL AA G+ E+L +LL NVN +A +G T L + N I + LL GA+ Sbjct: 26 DELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH 85 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 KD+ G +H+A G + + LL+ A VN D PLH AA + + V L+ Sbjct: 86 AKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLS 145 Query: 125 HTASNVGHRNHKGDTACDLA 144 H A H G +A D+A Sbjct: 146 HGADPTLVNCH-GKSAVDMA 164 Score = 105 bits (262), Expect = 9e-24, Method: Composition-based stats. Identities = 41/122 (33%), Positives = 56/122 (45%), Gaps = 4/122 (3%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTG--FAVIHDAARAGFLDTLQTLLEFQADVNIE 99 L+ + GN E LL N + G +H AA + +Q LL+ ADV+ + Sbjct: 29 LEAARSGNEEKLMALL-TPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAK 87 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 D G +PLH A GH V E L+KH A V + T A R EV SL+ ++ Sbjct: 88 DKGGLVPLHNACSYGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNRVEVCSLLLSH 146 Query: 160 GA 161 GA Sbjct: 147 GA 148 Score = 99.6 bits (247), Expect = 5e-22, Method: Composition-based stats. Identities = 41/158 (25%), Positives = 66/158 (41%), Gaps = 9/158 (5%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL----GNPEIARRLLLRGA 61 G+ L AA DL ++ L + Q TAL ++A LL +GA Sbjct: 179 GHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGA 238 Query: 62 NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 N + K++ +H AA D ++ L + A +N D+ G LH AA GHL+ Sbjct: 239 NVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGHLQTCRL 298 Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 L+ + S+ + +G T A G V ++ + Sbjct: 299 LLSYG-SDPSIISLQGFT----AAQMGNEAVQQILSES 331 Score = 90.4 bits (223), Expect = 3e-19, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 75/212 (35%), Gaps = 59/212 (27%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGAN---- 62 L +A + G E LL++ VNA + + T L N E+ LL GA+ Sbjct: 94 PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLV 153 Query: 63 -------------PDLKDR-------------------------------------TGFA 72 P+L++R + Sbjct: 154 NCHGKSAVDMAPTPELRERLTYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHET 213 Query: 73 VIHDAARAGFLD---TLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129 +H A + + LL A+VN ++ + PLH+AA+ H V+E L KH A Sbjct: 214 ALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK- 272 Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + + G TA A L G + L+ + G+ Sbjct: 273 MNALDSLGQTALHRAALAGHLQTCRLLLSYGS 304 Score = 77.3 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 29/89 (32%), Positives = 46/89 (51%), Gaps = 2/89 (2%) Query: 74 IHDAARAGFLDTLQTLLE-FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132 + +AAR+G + L LL + + D + PLHLAA +R+V+ L++H A +V Sbjct: 28 LLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGA-DVHA 86 Query: 133 RNHKGDTACDLARLYGRNEVVSLMQANGA 161 ++ G A YG EV L+ +GA Sbjct: 87 KDKGGLVPLHNACSYGHYEVTELLLKHGA 115 >5GP7-A nrPDB Length = 169 Score = 140 bits (354), Expect = 2e-34, Method: Composition-based stats. Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 3/138 (2%) Query: 9 LASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L AA +G L ++ L N+N G T L + N E+A LL GA+ + + Sbjct: 13 LLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQ 72 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D+ G +H+AA G +D L+++ VN D PLH AA++G ++ L+ H Sbjct: 73 DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHG 132 Query: 127 ASNVGHRNHKGDTACDLA 144 A + +N +G T DLA Sbjct: 133 A-DPTMKNQEGQTPLDLA 149 Score = 91.6 bits (226), Expect = 2e-19, Method: Composition-based stats. Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPDLK 66 L AA +LE LL++ +VNAQ+ G L G+ +IA L+ + Sbjct: 46 PLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNAT 105 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAK 112 D+ F +H+AA+ G LL AD +++ EG PL LA Sbjct: 106 DKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLATA 151 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 4/62 (6%) Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGD--TACDLARLYGRNEVVSLMQAN 159 G+ L AAK+G L V+ L N+ R+ +G T LA Y EV + + Sbjct: 8 RGDAALLDAAKKGCLARVQKLCT--PENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEH 65 Query: 160 GA 161 GA Sbjct: 66 GA 67 >4NIK-A nrPDB Length = 230 Score = 139 bits (350), Expect = 6e-34, Method: Composition-based stats. Identities = 45/155 (29%), Positives = 76/155 (49%), Gaps = 2/155 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKD 67 L A + G E + LLQ V VN ++ G + L + G EI + LL +GA + + Sbjct: 48 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 107 Query: 68 RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127 + G +H AA + LLE A+ + +D+ +H AA +G+L+++ L+ + A Sbjct: 108 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 167 Query: 128 SNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 S ++ +G+T LA R E L+ + GA Sbjct: 168 S-TNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 201 Score = 131 bits (329), Expect = 2e-31, Method: Composition-based stats. Identities = 54/140 (38%), Positives = 69/140 (49%), Gaps = 2/140 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDL 65 + L AA+ G E + +LL VNA N G T L N EIA LL GANPD Sbjct: 79 SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 138 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 KD +H AA G L + LL ++A NI+D EGN PLHLA E + + LV Sbjct: 139 KDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQ 198 Query: 126 TASNVGHRNHKGDTACDLAR 145 AS + N + T +A+ Sbjct: 199 GAS-IYIENKEEKTPLQVAK 217 Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats. Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 5/158 (3%) Query: 13 AARGDLEQLT-SLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTG 70 A G LE+L S+L + + RTAL G+ EI LL G + KD G Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 77 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 ++ +H AA AG + ++ LL A VN + G PLH AA + + L++ +N Sbjct: 78 WSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANP 136 Query: 131 GHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 ++H TA A G +++ ++ A +TN+Q Sbjct: 137 DAKDHYEATAMHRAAAKGNLKMIHILLYYKA--STNIQ 172 Score = 31.1 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 23/51 (45%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLL 58 L A +E+ L+ ++ +N +T LQV K G I +R++ Sbjct: 179 PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGGLGLILKRMVE 229 >2DWZ-A nrPDB Length = 231 Score = 138 bits (349), Expect = 7e-34, Method: Composition-based stats. Identities = 43/155 (27%), Positives = 75/155 (48%), Gaps = 2/155 (1%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKD 67 L A + G E + LLQ V VN ++ G + L + G EI + LL++GA+ + + Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVN 103 Query: 68 RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127 + G +H AA + LLE A+ + +D+ +H AA +G+L++V L+ Sbjct: 104 QNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILL-FYK 162 Query: 128 SNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 ++ ++ +G+T LA R E + GA Sbjct: 163 ASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGAS 197 Score = 135 bits (339), Expect = 1e-32, Method: Composition-based stats. Identities = 55/140 (39%), Positives = 71/140 (50%), Gaps = 2/140 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPDL 65 + L AA+ G E + +LL +VNA N G T L N EIA LL GANPD Sbjct: 75 SPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDA 134 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 KD +H AA G L + LL ++A NI+D EGN PLHLA E + +FLV Sbjct: 135 KDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQ 194 Query: 126 TASNVGHRNHKGDTACDLAR 145 AS + N + T +A+ Sbjct: 195 GAS-IYIENKEEKTPLQVAK 213 Score = 116 bits (291), Expect = 5e-27, Method: Composition-based stats. Identities = 46/158 (29%), Positives = 73/158 (46%), Gaps = 5/158 (3%) Query: 13 AARGDLEQLT-SLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTG 70 A G L++L +L + + RTAL G+ EI LL G + KD G Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 ++ +H AA AG + ++ LL A VN + G PLH AA + + L++ +N Sbjct: 74 WSPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANP 132 Query: 131 GHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 168 ++H TA A G ++V ++ A +TN+Q Sbjct: 133 DAKDHYDATAMHRAAAKGNLKMVHILLFYKA--STNIQ 168 Score = 31.5 bits (70), Expect = 0.16, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 22/51 (43%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLL 58 L A +E+ L+ ++ +N +T LQV K G I +RL Sbjct: 175 PLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRLAE 225 >4O1O-A nrPDB Length = 717 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 46/160 (28%), Positives = 67/160 (41%), Gaps = 11/160 (6%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVM-KLGNPEIARRLLLRGANPDLK 66 L A D+EQ+ LL+ + N Q +G + L ++ + ++ LL GA+P L+ Sbjct: 12 LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLR 71 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 R G A G + LQ LL DVN D G AA G + + FL ++ Sbjct: 72 KRNGATPFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENG 131 Query: 127 ASNVGHRNHK---------GDTACDLARLYGRNEVVSLMQ 157 A HR K G TA A G VV+++ Sbjct: 132 ADVNMHRKTKQDQERIRKGGATALMDAAEKGHVGVVTILL 171 Score = 114 bits (286), Expect = 2e-26, Method: Composition-based stats. Identities = 34/120 (28%), Positives = 62/120 (51%), Gaps = 2/120 (1%) Query: 43 QVMKLGNPEIARRLLLRGANPDLKDRT-GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101 Q ++ + E R+LL RGA+ + ++ G++ +H A + D + LL+ AD + Sbjct: 14 QAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKR 73 Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 G P +A G++R+++ L+ + +V + G TA A +YGR E + + NGA Sbjct: 74 NGATPFIIAGITGNVRLLQLLLPNV-EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGA 132 Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats. Identities = 48/175 (27%), Positives = 79/175 (45%), Gaps = 16/175 (9%) Query: 3 EPWG-NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRG 60 E WG + L SA + + LL++ + + G T + + GN + + LL Sbjct: 39 EEWGWSPLHSAVQMDSEDLVALLLKHGADPCLRKRNGATPFIIAGITGNVRLLQLLLPNV 98 Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI-----EDNE-----GNLPLHLA 110 + + D GF +AA G ++ L+ L E ADVN+ +D E G L A Sbjct: 99 EDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTKQDQERIRKGGATALMDA 158 Query: 111 AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLY---GRNE-VVSLMQANGA 161 A++GH+ VV L+ + V R++ G A A L G+ + + L+ +GA Sbjct: 159 AEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGA 213 Score = 99.6 bits (247), Expect = 5e-22, Method: Composition-based stats. Identities = 46/200 (23%), Positives = 73/200 (36%), Gaps = 49/200 (24%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTA-LQVMKLGNPEIARRLLLRGANPDL----- 65 A G++ L LL N +VN + G TA ++ G E R L GA+ ++ Sbjct: 82 AGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTK 141 Query: 66 KD-----RTGFAVIHDAARAGFLDTL---------------------------------- 86 +D + G + DAA G + + Sbjct: 142 QDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKA 201 Query: 87 ----QTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142 + LL+ ADVN+ PL LA + +L +V+ L++ V + +G TA Sbjct: 202 KAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALL 261 Query: 143 LARLYGRNEVVSLMQANGAG 162 LA E+ L+ GA Sbjct: 262 LAVELRLEEIAKLLCHRGAS 281 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 41/123 (33%), Gaps = 11/123 (8%) Query: 22 TSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLKDRTGFAVIHDAAR 79 LL + +VN + +T L + N ++ + LL + + DR G + A Sbjct: 206 RLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVE 265 Query: 80 AGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHL--RVVEFLVKHTASNVGHRNHKG 137 + + L A N D +A + +V+FL H A + Sbjct: 266 LRLEEIAKLLCHRGASTNCGDL-------VAIARRNYDSDLVKFLRLHKAGEDFRPPAEN 318 Query: 138 DTA 140 Sbjct: 319 WKP 321 >6AUN-A nrPDB Length = 752 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 7/145 (4%) Query: 4 PWGNELASA---AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60 P G + +A + +G E + S+ + ++ + +G + L K N E+AR LL RG Sbjct: 251 PSGFPIHTAMKFSQKGCAEMIISMDSSQIH-SKDPRYGASPLHWAK--NAEMARMLLKRG 307 Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 + D G +H A D + LL + A+ GN PLHLA + ++ +++ Sbjct: 308 CDVDSTSAAGNTALHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEMIK 367 Query: 121 FLVKHTASNVGHRNHKGDTACDLAR 145 L+ A V N G+T +A Sbjct: 368 ALIVFGA-EVDTPNDFGETPAFMAS 391 Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats. Identities = 39/157 (24%), Positives = 58/157 (36%), Gaps = 8/157 (5%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN-PDL 65 L A G E + LL N N G + MK A ++ ++ Sbjct: 223 PLHLACQMGKQEMVRVLLLCNARCNVMGPSGF-PIHTAMKFSQKGCAEMIISMDSSQIHS 281 Query: 66 KD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 KD R G + +H A + + LL+ DV+ GN LH+A V L+ Sbjct: 282 KDPRYGASPLHWA---KNAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMVLLT 338 Query: 125 HTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + A N G G+T LA E++ + GA Sbjct: 339 YGA-NAGTPGEHGNTPLHLAISKDNMEMIKALIVFGA 374 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 70/195 (35%), Gaps = 41/195 (21%) Query: 8 ELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN--PD 64 L A +GD E L L+Q + ++ + G TA G+ +LL + A+ + Sbjct: 155 PLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLN 214 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIED------------------------ 100 ++ G +H A + G + ++ LL A N+ Sbjct: 215 QVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCAEMIISM 274 Query: 101 ----------NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN 150 G PLH A + + L+K +V + G+TA +A + R Sbjct: 275 DSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRG-CDVDSTSAAGNTALHVAVMRNRF 330 Query: 151 EVVSLMQANGAGGAT 165 + V ++ GA T Sbjct: 331 DCVMVLLTYGANAGT 345 Score = 87.7 bits (216), Expect = 2e-18, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 49/96 (51%), Gaps = 1/96 (1%) Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 + G +H A R G + L L+++ A +++ DN+G H A + + +V++ L K+ Sbjct: 149 NEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKN 208 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 ++ + N +G T LA G+ E+V ++ A Sbjct: 209 ASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNA 244 Score = 80.4 bits (197), Expect = 3e-16, Method: Composition-based stats. Identities = 37/177 (20%), Positives = 58/177 (32%), Gaps = 46/177 (25%) Query: 35 NGFGRTALQVMK-LGNPEIARRLLLR-GANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF 92 N G T L + G+ EI L+ A D+ D G H A + LQ L + Sbjct: 149 NEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKN 208 Query: 93 Q-ADVNIEDNEGNLPLHLAAKEGHLRVVEFLV---------------------------- 123 A +N + +G PLHLA + G +V L+ Sbjct: 209 ASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPSGFPIHTAMKFSQKGCA 268 Query: 124 ----KHTASNVGHRN-HKGDTACDLARLYGRNEVVSLMQANG-------AGGATNLQ 168 +S + ++ G + A+ E+ ++ G A G T L Sbjct: 269 EMIISMDSSQIHSKDPRYGASPLHWAK---NAEMARMLLKRGCDVDSTSAAGNTALH 322 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 1/110 (0%) Query: 54 RRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKE 113 +L ++ ++ + V H A G + + E+ EG PLHLA ++ Sbjct: 104 VEVLQHLSDL-IRSHPSWTVTHLAVELGIRECFHHSRIISCANSTENEEGCTPLHLACRK 162 Query: 114 GHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGG 163 G ++ LV++ + + ++KG+TA A ++V+ L+ N + G Sbjct: 163 GDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAG 212 >1WG0-A nrPDB Length = 243 Score = 128 bits (322), Expect = 1e-30, Method: Composition-based stats. Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 6/158 (3%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVN---AQNGFGRTALQVMK-LGNPEIARRLLLRGANP 63 L + + E + LL NVN + G T + +GN E+ + L R P Sbjct: 39 PLHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKP 98 Query: 64 DLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 DL T G +H A + + Q L+E A V I+D +PLH AA G L+++E Sbjct: 99 DLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIEL 158 Query: 122 LVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 L S V ++ +G T A G + L+ Sbjct: 159 LCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEK 196 Score = 88.5 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 41/156 (26%), Positives = 65/156 (41%), Gaps = 7/156 (4%) Query: 8 ELASAAARGDLEQLTSLLQN--NVNVNAQNGFGRTALQVMKLGN-PEIARRLLLRGANPD 64 A + G+LE + SL ++N G T L + E+++ L+ GA+ Sbjct: 75 PFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVR 134 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-VNIEDNEGNLPLHLAAKEGHLRVVEFLV 123 +KD+ +H AA G L ++ L VN +D +G PL A EGH LV Sbjct: 135 IKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLV 194 Query: 124 KHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 + + ++KG A D+A +V N Sbjct: 195 EKYGAEYDLVDNKGAKAEDVAL---NEQVKKFFLNN 227 Score = 74.2 bits (181), Expect = 2e-14, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 6/128 (4%) Query: 41 ALQVMKLGNP--EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI 98 L + N ++ L + + KD+ G +H + + LL +VN+ Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 99 EDN---EGNLPLHLAAKEGHLRVVEFLVKHT-ASNVGHRNHKGDTACDLARLYGRNEVVS 154 +D G P H+A G+L VV+ L ++ ++G T LA EV Sbjct: 65 DDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQ 124 Query: 155 LMQANGAG 162 + NGA Sbjct: 125 FLIENGAS 132 Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 19/90 (21%), Positives = 35/90 (38%), Gaps = 3/90 (3%) Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNI-EDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129 +H A +Q LL + + + +D +G +PLH + + FL+ + Sbjct: 3 NYPLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENV 62 Query: 130 V--GHRNHKGDTACDLARLYGRNEVVSLMQ 157 + + G T +A G EVV + Sbjct: 63 NLDDYPDDSGWTPFHIACSVGNLEVVKSLY 92 >2A5E-A nrPDB Length = 156 Score = 126 bits (318), Expect = 3e-30, Method: Composition-based stats. Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Query: 3 EPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN 62 EP + LA+AAARG +E++ +LL+ NA N +GR +QVM +G+ +A LLL GA Sbjct: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAE 69 Query: 63 PDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 P+ D +HDAAR GFLDTL L A +++ D G LP+ LA + GH V + Sbjct: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129 Query: 122 LVKHTASNVGHRNHKGDTA 140 L G + + D A Sbjct: 130 LRAAAGGTRGSNHARIDAA 148 Score = 70.8 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 34/120 (28%), Positives = 47/120 (39%), Gaps = 3/120 (2%) Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103 G E R LL GA P+ + G I G + LL A+ N D Sbjct: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRPIQV-MMMGSARVAELLLLHGAEPNCADPAT 77 Query: 104 NL-PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 P+H AA+EG L + L + A + R+ G DLA G +V ++A G Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGAR-LDVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136 >6EMK-G nrPDB Length = 426 Score = 124 bits (311), Expect = 2e-29, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 4/118 (3%) Query: 48 GNPEIARRLLLRGANP--DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--IEDNEG 103 GN I +RLL R + ++ G++ +H A+ G L++ D + I+ +G Sbjct: 16 GNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKG 75 Query: 104 NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 N +HLA +GH + + L++ + HR G +A + + +SL+ GA Sbjct: 76 NTCVHLALMKGHEQTLHLLLQQFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGA 133 Score = 87.3 bits (215), Expect = 3e-18, Method: Composition-based stats. Identities = 33/169 (19%), Positives = 65/169 (38%), Gaps = 10/169 (5%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGF--GRTALQVMKLGNPEIARRLLLR 59 +E + L A+ G L+Q + + G T + + + E LLL+ Sbjct: 37 SENGWSSLHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQ 96 Query: 60 GAN--PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLR 117 + + G A IH A + L L+ AD+ + D G+ PLH+ + G + Sbjct: 97 QFPRFINHRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSIS 156 Query: 118 VVEFLVKHTASNV--GHRNHKGDTACDLA----RLYGRNEVVSLMQANG 160 ++ L+ ++ R+ D+A ++V+ ++ G Sbjct: 157 CMKMLLNEGEVSLDDNVRDKGNWKPIDVAQTFEVGNIYSKVLKEVKKKG 205 >5ET1-A nrPDB Length = 353 Score = 122 bits (306), Expect = 7e-29, Method: Composition-based stats. Identities = 48/196 (24%), Positives = 80/196 (40%), Gaps = 38/196 (19%) Query: 10 ASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVM-KLGNPEIARRLLLRGA------ 61 AAA G L L LL Q V ++ G T L + + G+P++ + LL +G Sbjct: 76 HDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAIT 135 Query: 62 -----------------------------NPDLKDRTGFAVIHDAARAGFLDTLQTLL-E 91 + + G ++ A + G L+ + L+ E Sbjct: 136 TDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQE 195 Query: 92 FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE 151 AD ++ +G PLH AA+ GH V+ +LV + ++H G TA A G + Sbjct: 196 CSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTK 255 Query: 152 VVSLMQANGAGGATNL 167 V+S + +GA + +L Sbjct: 256 VLSWLLLHGAEISQDL 271 Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats. Identities = 52/160 (32%), Positives = 79/160 (49%), Gaps = 8/160 (5%) Query: 8 ELASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLR-GANPD 64 + AAA+GDL L L+ VNAQ G T L + G+ E+ + L+ A+P Sbjct: 142 PIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLVQECSADPH 201 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN--IEDNEGNLPLHLAAKEGHLRVVEFL 122 L+ + G +H AA+ G L L+ F ADV+ +D++G +H AA GH +V+ +L Sbjct: 202 LRAQDGMTPLHAAAQMGHNPVLVWLVSF-ADVSFSEQDHDGATAMHFAASRGHTKVLSWL 260 Query: 123 VKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 + H A ++ G T A G E ++ NGAG Sbjct: 261 LLHGAEI--SQDLWGGTPLHDAAENGELECCQILAVNGAG 298 Score = 98.1 bits (243), Expect = 1e-21, Method: Composition-based stats. Identities = 41/154 (26%), Positives = 60/154 (38%), Gaps = 5/154 (3%) Query: 6 GNELASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 L A G LE L+ + + + + + G T L L+ A+ Sbjct: 174 ATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVSFADVS 233 Query: 65 L--KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122 +D G +H AA G L LL A+++ D G PLH AA+ G L + L Sbjct: 234 FSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEISQ-DLWGGTPLHDAAENGELECCQIL 292 Query: 123 VKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 + A + R+H G TA DLA G + Sbjct: 293 AVNGAG-LDVRDHDGYTAADLAEFNGHTHCSRYL 325 Score = 87.3 bits (215), Expect = 3e-18, Method: Composition-based stats. Identities = 45/157 (28%), Positives = 66/157 (42%), Gaps = 4/157 (2%) Query: 7 NELASAAARGDLEQLTSLLQNNV-NVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGANPD 64 + AA RGDL+ L SL + + ++ + + G R L+ A P Sbjct: 5 EQALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPA 64 Query: 65 L-KDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNIEDNEGNLPLHLAAKEGHLRVVEFL 122 + + R G HDAA G+L LQ LL V +DN G LHLAA+ GH VV++L Sbjct: 65 VSRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWL 124 Query: 123 VKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 + +N G A G + L+ + Sbjct: 125 LYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGH 161 Score = 84.6 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 37/126 (29%), Positives = 59/126 (46%), Gaps = 2/126 (1%) Query: 41 ALQVMKLGNPEIARRLLLRGA-NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNI- 98 ALQ + G+ ++ R L G P L+D +H AAR+G L L+ L+E A + Sbjct: 7 ALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVS 66 Query: 99 EDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158 G P H AA G+L +++L+ V +++ G T LA +G +VV + Sbjct: 67 RARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLY 126 Query: 159 NGAGGA 164 G + Sbjct: 127 QGGANS 132 Score = 80.4 bits (197), Expect = 4e-16, Method: Composition-based stats. Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 3/138 (2%) Query: 8 ELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65 L +AA G L L+ +V+ + Q+ G TA+ G+ ++ LLL GA Sbjct: 210 PLHAAAQMGHNPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEI-S 268 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 +D G +HDAA G L+ Q L A +++ D++G LA GH +L Sbjct: 269 QDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRTV 328 Query: 126 TASNVGHRNHKGDTACDL 143 ++ HR D + DL Sbjct: 329 QTLSLEHRVLSRDQSMDL 346 >4OT9-A nrPDB Length = 359 Score = 122 bits (306), Expect = 8e-29, Method: Composition-based stats. Identities = 45/163 (27%), Positives = 68/163 (41%), Gaps = 9/163 (5%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVM---KLGNPEIARRLLLRGAN-- 62 L A G ++ LL+ + + G +A+ + G PE+ R LL GA Sbjct: 124 PLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAV 183 Query: 63 ---PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG-NLPLHLAAKEGHLRV 118 + D G +H A RA + L L++ A+V + +G LHLA + L + Sbjct: 184 PQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGL 243 Query: 119 VEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 V LV +NV R G+T LA G + L+ GA Sbjct: 244 VTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGA 286 Score = 84.6 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 14/154 (9%) Query: 22 TSLLQNNVNV-NAQNGFGRTALQVM----KLGNPEIARRLLLRGAN---PDLKDRTGFAV 73 +LL ++ AQ+ G T L + + E ++ + +L + Sbjct: 65 RALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTP 124 Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA--AKEGHLRVVEFLVKHTASNV- 130 +H A G + LL AD + D G+ +HLA A G ++ L++ A V Sbjct: 125 LHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVP 184 Query: 131 ---GHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + +G LA E + L+ +GA Sbjct: 185 QLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGA 218 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 3/103 (2%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNG-FGRTALQVM-KLGNPEIARRLLLR-GANPD 64 + A E L L+ + V A GRTAL + ++ + L+ + AN + Sbjct: 197 PVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVN 256 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107 + G +H AA G+ + LL+ AD++ E+ E PL Sbjct: 257 ARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299 Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 5/86 (5%) Query: 84 DTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLV-----KHTASNVGHRNHKGD 138 D L + + +D G+ PLHLA G V+E +V V NH Sbjct: 63 DARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQ 122 Query: 139 TACDLARLYGRNEVVSLMQANGAGGA 164 T LA + G+ VVS + GA A Sbjct: 123 TPLHLAVITGQTSVVSFLLRVGADPA 148 >5DND-A nrPDB Length = 588 Score = 121 bits (303), Expect = 2e-28, Method: Composition-based stats. Identities = 50/164 (30%), Positives = 73/164 (44%), Gaps = 9/164 (5%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRT-ALQVMKLGNPEIARRLLLRG 60 + P G+ L AR L SL + Q+ + AL + G E + L+ G Sbjct: 391 SSPPGSTLGQGVAR-----LFSLFGCQEEDSVQDAVMPSLALALAHAGELEALQALMELG 445 Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 ++ LKD G ++H AAR G + LL DVN D +G PL LA + H + Sbjct: 446 SDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIR 505 Query: 121 FLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGA 164 L K A + ++ K D +L RL R ++ +QA G GA Sbjct: 506 LLRKAGAC-LSPQDLK-DAGTELCRLASRADMEG-LQAWGQAGA 546 Score = 29.2 bits (64), Expect = 0.96, Method: Composition-based stats. Identities = 17/56 (30%), Positives = 25/56 (44%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61 G EL A+R D+E L + Q ++ GR+AL V + + LL A Sbjct: 523 GTELCRLASRADMEGLQAWGQAGADLQQPGYDGRSALCVAEAAGNQEVLALLRNLA 578 >1D9S-A nrPDB Length = 136 Score = 117 bits (293), Expect = 3e-27, Method: Composition-based stats. Identities = 50/123 (40%), Positives = 71/123 (57%), Gaps = 1/123 (0%) Query: 1 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRG 60 + LA+AAARG +E + LL+ + NA N FGR +QVM +G+ ++A LLL G Sbjct: 8 LGGSSDAGLATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHG 67 Query: 61 ANPDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119 A P+ D +HDAAR GFLDTL L A +++ D G LP+ LA ++GH + Sbjct: 68 AEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIA 127 Query: 120 EFL 122 +L Sbjct: 128 RYL 130 Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 5/121 (4%) Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103 G E R+LL GA+P+ +R G I G + LL A+ N D Sbjct: 19 AAARGQVETVRQLLEAGADPNALNRFGRRPIQV-MMMGSAQVAELLLLHGAEPNCADPAT 77 Query: 104 NL-PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 P+H AA+EG L + L + A + + G DLA G ++ + + A Sbjct: 78 LTRPVHDAAREGFLDTLVVLHRAGAR-LDVCDAWGRLPVDLAEEQGHRDIARYL--HAAT 134 Query: 163 G 163 G Sbjct: 135 G 135 >5D68-A nrPDB Length = 486 Score = 111 bits (279), Expect = 1e-25, Method: Composition-based stats. Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 5/124 (4%) Query: 41 ALQ-VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ-ADVNI 98 L G+ E+ RLL + + D +A IH A G ++ + LLE + N+ Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100 Query: 99 EDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLA---RLYGRNEVVSL 155 + + + PLH AA GH +V+ L+ H ++ + +G + ++ + E L Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 160 Query: 156 MQAN 159 ++ Sbjct: 161 LKEA 164 Score = 83.9 bits (206), Expect = 3e-17, Method: Composition-based stats. Identities = 32/103 (31%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRG-ANPDL 65 L +A GD E L+ LL +VN + + G E R LL +G NP+L Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 100 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPL 107 + + +H AA G + +Q LL + D +I D +G PL Sbjct: 101 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 143 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 22/55 (40%), Gaps = 1/55 (1%) Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 PLH +A EG ++ L+ +V + A YG+ E ++ G Sbjct: 41 PLHRSACEGDSELLSRLLSE-RFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG 94 Score = 35.7 bits (81), Expect = 0.009, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 25/60 (41%), Gaps = 4/60 (6%) Query: 7 NELASAAARGDLEQLTSLL-QNNVNVNAQNGFGRTALQVMKL---GNPEIARRLLLRGAN 62 + L AA G E + LL + + + GR+ L + + N E A +LL N Sbjct: 107 SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAIN 166 >3EHQ-A nrPDB Length = 222 Score = 106 bits (264), Expect = 6e-24, Method: Composition-based stats. Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 5/130 (3%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61 AE N L AA RG+L L L N V VN + G TAL G + +L Sbjct: 70 AESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQP 129 Query: 62 NP--DLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119 N + +++ G +H AA G+ D +Q LL A ++ + E L +A + Sbjct: 130 NIELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMAT---NAACA 186 Query: 120 EFLVKHTASN 129 L K ++ Sbjct: 187 SLLKKKQGTD 196 Score = 105 bits (263), Expect = 8e-24, Method: Composition-based stats. Identities = 30/89 (33%), Positives = 44/89 (49%) Query: 73 VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGH 132 +H+AA+ G L L+ L+ + VN D G+ L+ A GH +VE L + Sbjct: 76 PLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQ 135 Query: 133 RNHKGDTACDLARLYGRNEVVSLMQANGA 161 +N GDTA A G ++V L+ A GA Sbjct: 136 QNKLGDTALHAAAWKGYADIVQLLLAKGA 164 >5UQE-A nrPDB Length = 520 Score = 98.1 bits (243), Expect = 2e-21, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 41/82 (50%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++ Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 483 Query: 137 GDTACDLARLYGRNEVVSLMQA 158 +T D A +G ++V ++Q Sbjct: 484 NNTPMDEALHFGHHDVFKILQE 505 Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 1/82 (1%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLE-FQADVNIED 100 L G+ RR L + + +D +H AA G ++ ++ LLE + + +D Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 481 Query: 101 NEGNLPLHLAAKEGHLRVVEFL 122 N P+ A GH V + L Sbjct: 482 RWNNTPMDEALHFGHHDVFKIL 503 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLK 66 L AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP K Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92 DR + +A G D + L E+ Sbjct: 481 DRWNNTPMDEALHFGHHDVFKILQEY 506 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 L AA G + + +A ++ R++ TA +A G EVV + Sbjct: 421 LLFAAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 472 >3ZKJ-A nrPDB Length = 261 Score = 97.7 bits (242), Expect = 2e-21, Method: Composition-based stats. Identities = 37/156 (23%), Positives = 63/156 (40%), Gaps = 3/156 (1%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65 + + AA G L +L+ VN + L L G+ + LL GA + Sbjct: 5 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 64 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 + +A +G D + LL+ A V +++ P+H AA+ GH+ V L+ + Sbjct: 65 VTADWHTPLFNACVSGSWDCVNLLLQHGASV-QPESDLASPIHEAARRGHVECVNSLIAY 123 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 + +H G T LA + V + +GA Sbjct: 124 GGNIDHKISHLG-TPLYLACENQQRACVKKLLESGA 158 Score = 93.9 bits (232), Expect = 3e-20, Method: Composition-based stats. Identities = 35/156 (22%), Positives = 66/156 (42%), Gaps = 4/156 (2%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGANPDL 65 + L A G L + LL++ VN T L G+ + LL GA+ Sbjct: 38 SPLHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP 97 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 + + IH+AAR G ++ + +L+ + +++ + + PL+LA + V+ L++ Sbjct: 98 ESDL-ASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLES 156 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGA 161 A +V + D+ E+ L+ GA Sbjct: 157 GA-DVN-QGKGQDSPLHAVARTASEELACLLMDFGA 190 Score = 89.2 bits (220), Expect = 8e-19, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 3/123 (2%) Query: 39 RTALQ-VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVN 97 + + G+ R L+ +G ++ + +H+A G L ++ LL+ A VN Sbjct: 4 WSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVN 63 Query: 98 IEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 + + PL A G V L++H AS + + A G E V+ + Sbjct: 64 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESDLA--SPIHEAARRGHVECVNSLI 121 Query: 158 ANG 160 A G Sbjct: 122 AYG 124 Score = 75.4 bits (184), Expect = 1e-14, Method: Composition-based stats. Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS 128 + ++ +H+AA G +L+ L+ VNI + PLH A GHL V+ L+KH A Sbjct: 2 SDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQ 61 Query: 129 NVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 V T A + G + V+L+ +GA Sbjct: 62 -VNGVTADWHTPLFNACVSGSWDCVNLLLQHGAS 94 Score = 27.2 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65 + L + A E L+ + A+N G+ ++++ +P +A+ L R P L Sbjct: 167 DSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESP-LAQLFLEREGPPSL 225 Query: 66 K 66 Sbjct: 226 M 226 >3UI2-A nrPDB Length = 244 Score = 95.8 bits (237), Expect = 7e-21, Method: Composition-based stats. Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%) Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62 PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+ Sbjct: 48 PW----WTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 102 Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 D +D R G +H AA + ++ L+E AD+ +ED G L LA Sbjct: 103 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 151 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 2/107 (1%) Query: 40 TALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 T E A LL + D D G + A G ++ L E AD++ Sbjct: 47 TPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHR 106 Query: 100 DNE-GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLAR 145 D G LH+AA VVE LV+ A ++ + +G TA +LAR Sbjct: 107 DMRGGLTALHMAAGYVRPEVVEALVELGA-DIEVEDERGLTALELAR 152 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%) Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 AAR L LLE + DV+ D G L A G + V L + A ++ Sbjct: 47 TPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGA-DLD 104 Query: 132 HRNHKG-DTACDLARLYGRNEVVSLMQANGA 161 HR+ +G TA +A Y R EVV + GA Sbjct: 105 HRDMRGGLTALHMAAGYVRPEVVEALVELGA 135 Score = 30.7 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 20/38 (52%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK 46 L AA E + +L++ ++ ++ G TAL++ + Sbjct: 115 LHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAR 152 >3DEO-A nrPDB Length = 183 Score = 95.0 bits (235), Expect = 2e-20, Method: Composition-based stats. Identities = 39/109 (35%), Positives = 59/109 (54%), Gaps = 7/109 (6%) Query: 4 PWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQ-VMKLGNPEIARRLLLRGAN 62 PW +AA + D + L+ LL++ +V+A + GRTAL V LG+ + R L GA+ Sbjct: 47 PW----WTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGAD 101 Query: 63 PDLKD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 D +D R G +H AA + ++ L+E AD+ +ED G L LA Sbjct: 102 LDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELA 150 Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 2/107 (1%) Query: 40 TALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 T E A LL + D D G + A G ++ L E AD++ Sbjct: 46 TPWWTAARKADEQALSQLLEDRDVDAVDENGRTALLFVAGLGSDKCVRLLAEAGADLDHR 105 Query: 100 DNE-GNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLAR 145 D G LH+AA VVE LV+ A ++ + +G TA +LAR Sbjct: 106 DMRGGLTALHMAAGYVRPEVVEALVELGA-DIEVEDERGLTALELAR 151 Score = 57.7 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 30/91 (32%), Positives = 40/91 (43%), Gaps = 3/91 (3%) Query: 72 AVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVG 131 AAR L LLE + DV+ D G L A G + V L + A ++ Sbjct: 46 TPWWTAARKADEQALSQLLEDR-DVDAVDENGRTALLFVAGLGSDKCVRLLAEAGA-DLD 103 Query: 132 HRNHKG-DTACDLARLYGRNEVVSLMQANGA 161 HR+ +G TA +A Y R EVV + GA Sbjct: 104 HRDMRGGLTALHMAAGYVRPEVVEALVELGA 134 Score = 30.3 bits (67), Expect = 0.38, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 20/38 (52%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK 46 L AA E + +L++ ++ ++ G TAL++ + Sbjct: 114 LHMAAGYVRPEVVEALVELGADIEVEDERGLTALELAR 151 >5U0K-A nrPDB Length = 141 Score = 93.5 bits (231), Expect = 4e-20, Method: Composition-based stats. Identities = 26/81 (32%), Positives = 42/81 (51%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 AA +G + L+ D+ +D + LH+AA EGH+ VV+FL++ N ++ Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKDRW 91 Query: 137 GDTACDLARLYGRNEVVSLMQ 157 G+ D A + EVV L+Q Sbjct: 92 GNIPLDDAVQFNHLEVVKLLQ 112 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 1/82 (1%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLE-FQADVNIED 100 L G+ RR L + + KD +H AA G ++ ++ L+E + + +D Sbjct: 30 LFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAKD 89 Query: 101 NEGNLPLHLAAKEGHLRVVEFL 122 GN+PL A + HL VV+ L Sbjct: 90 RWGNIPLDDAVQFNHLEVVKLL 111 Score = 60.7 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLK 66 L AA GD+ L + +++ ++ RTAL V G+ E+ + L+ NP K Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92 DR G + DA + L+ ++ L ++ Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQDY 114 >5U0J-A nrPDB Length = 140 Score = 92.3 bits (228), Expect = 8e-20, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 41/82 (50%) Query: 77 AARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHK 136 AA G + L+ D+ D + LH+AA EGH+ VV+FL++ N ++ Sbjct: 31 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRW 90 Query: 137 GDTACDLARLYGRNEVVSLMQA 158 +T D A +G ++V ++Q Sbjct: 91 NNTPMDEALHFGHHDVFKILQE 112 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 1/82 (1%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLE-FQADVNIED 100 L G+ RR L + + +D +H AA G ++ ++ LLE + + +D Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKD 88 Query: 101 NEGNLPLHLAAKEGHLRVVEFL 122 N P+ A GH V + L Sbjct: 89 RWNNTPMDEALHFGHHDVFKIL 110 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 2/86 (2%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLR-GANPDLK 66 L AA GD+ L + +++ ++ RTAL V G+ E+ + LL NP K Sbjct: 28 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 87 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEF 92 DR + +A G D + L E+ Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEY 113 Score = 33.8 bits (76), Expect = 0.035, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 1/53 (1%) Query: 107 LHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 L AA G + + +A ++ R++ TA +A G EVV + Sbjct: 28 LLFAAYTGDVSALRR-FALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEA 79 >2KXP-C nrPDB Length = 118 Score = 88.1 bits (217), Expect = 2e-18, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 1/103 (0%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPD 64 E A GDL+++ + +VN GR L G EI LLL+GA+ + Sbjct: 3 DKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADIN 62 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPL 107 D+ + A G + ++ LL AD ++ +G L Sbjct: 63 APDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105 Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 52/116 (44%), Gaps = 4/116 (3%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101 + +K G+ + + + +G + + G +H AA G L+ L+ LL AD+N D Sbjct: 7 MWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDK 66 Query: 102 EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 PL A EGH+ V+ L+ A + + G TA + + +L+Q Sbjct: 67 HHITPLLSAVYEGHVSCVKLLLSKGA-DKTVKGPDGLTALEAT---DNQAIKALLQ 118 Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 1/88 (1%) Query: 74 IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHR 133 A + G LD ++ + DVN G PLH AA G L ++EFL+ A ++ Sbjct: 6 FMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGA-DINAP 64 Query: 134 NHKGDTACDLARLYGRNEVVSLMQANGA 161 + T A G V L+ + GA Sbjct: 65 DKHHITPLLSAVYEGHVSCVKLLLSKGA 92 Score = 30.7 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 12/51 (23%), Positives = 20/51 (39%), Gaps = 3/51 (5%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLL 58 L SA G + + LL + + G TAL+ + + + LL Sbjct: 71 PLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEAT---DNQAIKALLQ 118 >6E2G-A nrPDB Length = 727 Score = 84.2 bits (207), Expect = 2e-17, Method: Composition-based stats. Identities = 38/177 (21%), Positives = 67/177 (37%), Gaps = 25/177 (14%) Query: 5 WGNELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGAN 62 W + L AA +++ L LL+ V+ + G TAL + N E A L+ Sbjct: 45 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPE 104 Query: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGN 104 + T G +H A ++ ++ LL A V+ G Sbjct: 105 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 164 Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN----EVVSLMQ 157 PL AA G +V L++H A ++ ++ G+T + L ++ +L+ Sbjct: 165 HPLSFAACVGSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220 Score = 69.6 bits (169), Expect = 5e-13, Method: Composition-based stats. Identities = 32/141 (22%), Positives = 51/141 (36%), Gaps = 19/141 (13%) Query: 40 TALQVMKLGN--PEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-- 95 + L + N + + L G K G +H AA L+ L+E + Sbjct: 47 SPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 96 ---VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA--------SNVGHRNHK----GDTA 140 + E EG LH+A ++ +V L+ A S +R H G+ Sbjct: 107 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 166 Query: 141 CDLARLYGRNEVVSLMQANGA 161 A G E+V L+ +GA Sbjct: 167 LSFAACVGSEEIVRLLIEHGA 187 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 34/146 (23%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54 L A ++ + +LL +V+A+ +G L +G+ EI R Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAARAGFLDTLQTLLEFQADVNIE------ 99 L+ GA+ +D G V+H A + L LL + +++ Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL-----LLSYDGGDHLKSLELVP 235 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKH 125 +N+G P LA EG++ + + L++ Sbjct: 236 NNQGLTPFKLAGVEGNIVMFQHLMQK 261 >3LJN-A nrPDB Length = 364 Score = 80.0 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 40/174 (22%), Positives = 67/174 (38%), Gaps = 27/174 (15%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDL 65 ++ AA +G +++ L++ V+ QN FG TAL + G + A+ L G Sbjct: 22 EKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG-EVHS 80 Query: 66 KDRTGFAVIHDAARAGFLDTLQTLLEFQAD--------VNIEDN-------------EGN 104 G IH A A D + L+E + +N D +G Sbjct: 81 LWH-GQKPIHLAVMANKTDLVVALVEGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQ 139 Query: 105 LPLHLAAKEG--HLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 LH G +L +++ LV+ AS ++ +T A + E + LM Sbjct: 140 TALHWCVGLGPEYLEMIKILVQLGASPT-AKDKADETPLMRAMEFRNREALDLM 192 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 32/141 (22%), Positives = 54/141 (38%), Gaps = 24/141 (17%) Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEG 103 + G + RRL+ G +P +++R G +H A + G +DT + L +V+ G Sbjct: 27 AARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG-EVHSL-WHG 84 Query: 104 NLPLHLAAKEGHLRVVEFLV-------KHTASNVGHRNH-------------KGDTACDL 143 P+HLA +V LV + S + + KG TA Sbjct: 85 QKPIHLAVMANKTDLVVALVEGAKERGQMPESLLNECDEREVNEIGSHVKHCKGQTALHW 144 Query: 144 ARLYG--RNEVVSLMQANGAG 162 G E++ ++ GA Sbjct: 145 CVGLGPEYLEMIKILVQLGAS 165 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 37/92 (40%), Gaps = 3/92 (3%) Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHT 126 D IH AAR G D ++ L+E I++ G LHLA K G + ++L Sbjct: 17 DDENMEKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG 76 Query: 127 ASNVGHRNHKGDTACDLARLYGRNEVVSLMQA 158 + G LA + + ++V + Sbjct: 77 EVHSLW---HGQKPIHLAVMANKTDLVVALVE 105 Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 30/186 (16%) Query: 9 LASAAARG--DLEQLTSLLQNNVNVNAQNGFGRTAL-QVMKLGNPEIARRLLLRGAN--- 62 L G LE + L+Q + A++ T L + M+ N E ++ + Sbjct: 142 LHWCVGLGPEYLEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSS 201 Query: 63 --PDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVE 120 D ++ G + +H A + D +E DVN+EDNE +PL+L+ + + + + Sbjct: 202 LRLDYANKQGNSHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTK 261 Query: 121 FLVKHTASNVGHRN--HKGDTAC----------DLARLYGRNEVVSLMQAN--------- 159 L++ T + H G T A + EV+ L+Q Sbjct: 262 ELLQKTDVFLIQACPYHNGTTVLPDRVVWLDFVPAAADPSKQEVLQLLQEKLDEVVRSLN 321 Query: 160 -GAGGA 164 GAGGA Sbjct: 322 TGAGGA 327 >6DMR-A nrPDB Length = 730 Score = 76.1 bits (186), Expect = 6e-15, Method: Composition-based stats. Identities = 42/176 (23%), Positives = 66/176 (37%), Gaps = 25/176 (14%) Query: 6 GNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 + L AA DL L LL N + + G TAL V L + A LL+ A Sbjct: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105 Query: 65 LKDRT------GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGNL 105 K+ G +H A L+ ++ LL A V+ G Sbjct: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEH 165 Query: 106 PLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN----EVVSLMQ 157 PL AA G +V L++H A ++ ++ G+T + L ++ +L+ Sbjct: 166 PLSFAACVGSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220 Score = 60.4 bits (145), Expect = 3e-10, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 56/151 (37%), Gaps = 43/151 (28%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54 L A +L + +LL +V+A+ +G L +G+ EI R Sbjct: 121 LHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAAR-----------AGFLDTLQTLLEFQA 94 L+ GA+ +D G V+H A + + L +L+ Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNLLLSYDEHSDHLQSLEL------ 234 Query: 95 DVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 + +++G P LA EG+ + + L++ Sbjct: 235 ---VPNHQGLTPFKLAGVEGNTVMFQHLMQK 262 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 40/182 (21%), Positives = 64/182 (35%), Gaps = 29/182 (15%) Query: 4 PWGN--ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGA 61 PW +L + G+ + ++ VN+ Q + L N ++LL Sbjct: 11 PWAQLQKLLISWPVGEQDWEQY--RDRVNMLQQERIRDSPLLQAAKENDLRLLKILLLNQ 68 Query: 62 NPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------NEGNLPLHLAAK 112 + D + R G +H AA L+ L+E A + G LH+A Sbjct: 69 SCDFQQRGAVGETALHVAALYDNLEAATLLME--AAPELAKEPALCEPFVGQTALHIAVM 126 Query: 113 EGHLRVVEFLVKHTASNVGHRNH-------------KGDTACDLARLYGRNEVVSLMQAN 159 +L +V L+ AS V R G+ A G E+V L+ + Sbjct: 127 NQNLNLVRALLARGAS-VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEH 185 Query: 160 GA 161 GA Sbjct: 186 GA 187 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 22/97 (22%), Positives = 34/97 (35%), Gaps = 5/97 (5%) Query: 71 FAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKH---- 125 + + AA+ L L+ LL D G LH+AA +L L++ Sbjct: 46 DSPLLQAAKENDLRLLKILLLNQSCDFQQRGAVGETALHVAALYDNLEAATLLMEAAPEL 105 Query: 126 TASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 G TA +A + +V + A GA Sbjct: 106 AKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142 >3T9K-A nrPDB Length = 390 Score = 76.1 bits (186), Expect = 7e-15, Method: Composition-based stats. Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 3/106 (2%) Query: 57 LLRGANPDLKD--RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEG 114 L GA+ + + + + A A L + LL+ A+VN D+ G PLH A G Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279 Query: 115 HLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 H + +K A ++G R+ +G +A ++V+L++ Sbjct: 280 HTGLACLFLKRGA-DLGARDSEGRDPLTIAMETANADIVTLLRLAK 324 Score = 74.2 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 4/118 (3%) Query: 25 LQNNVNVNAQNGF--GRTAL-QVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAG 81 L + +VN NG T L Q + LL GAN + D G +H A G Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279 Query: 82 FLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFL-VKHTASNVGHRNHKGD 138 L+ AD+ D+EG PL +A + + +V L + + GD Sbjct: 280 HTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLAKMREAEAAQGQAGD 337 Score = 56.5 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 26/88 (29%), Positives = 34/88 (38%), Gaps = 1/88 (1%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLK 66 L A A L LLQN NVN + GR L LG+ +A L RGA+ + Sbjct: 238 PLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGAR 297 Query: 67 DRTGFAVIHDAARAGFLDTLQTLLEFQA 94 D G + A D + L + Sbjct: 298 DSEGRDPLTIAMETANADIVTLLRLAKM 325 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 3/74 (4%) Query: 90 LEFQADVNIED--NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLY 147 L ADVN + + PL A L EFL+++ A NV + G A + Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGA-NVNQADSAGRGPLHHATIL 278 Query: 148 GRNEVVSLMQANGA 161 G + L GA Sbjct: 279 GHTGLACLFLKRGA 292 >2RFA-A nrPDB Length = 232 Score = 75.8 bits (185), Expect = 9e-15, Method: Composition-based stats. Identities = 38/167 (22%), Positives = 63/167 (37%), Gaps = 21/167 (12%) Query: 5 WGNELASAAARGDLEQLTSLLQ-NNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGAN 62 W + L AA D++ L+ LL+ V+ + G TAL + N E A L+ Sbjct: 3 WESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 62 Query: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGN 104 + T G +H A ++ ++ LL A V+ G Sbjct: 63 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 122 Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNE 151 PL AA G +V L++H A ++ ++ G+T + L Sbjct: 123 HPLSFAACVGSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKT 168 Score = 62.7 bits (151), Expect = 7e-11, Method: Composition-based stats. Identities = 32/141 (22%), Positives = 51/141 (36%), Gaps = 19/141 (13%) Query: 40 TALQVMKLGNPEIA--RRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-- 95 + L + N A + L G + G +H AA L+ L+E + Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64 Query: 96 ---VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA--------SNVGHRNHK----GDTA 140 + E EG LH+A ++ +V L+ A S +R H G+ Sbjct: 65 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHP 124 Query: 141 CDLARLYGRNEVVSLMQANGA 161 A G E+V L+ +GA Sbjct: 125 LSFAACVGSEEIVRLLIEHGA 145 Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 39/96 (40%), Gaps = 5/96 (5%) Query: 72 AVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 + + AA+ + L LL+F +V+ G LH+AA +L L++ V Sbjct: 5 SPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 64 Query: 131 GHRNH----KGDTACDLARLYGRNEVVSLMQANGAG 162 +G TA +A + +V + A GA Sbjct: 65 FEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 100 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 34/146 (23%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54 L A ++ + +LL +V+A+ +G L +G+ EI R Sbjct: 79 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 138 Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAARAGFLDTLQTLLEFQADVNIE------ 99 L+ GA+ +D G V+H A + L LL + +++ Sbjct: 139 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL-----LLSYDGGDHLKSLELVP 193 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKH 125 +N+G P LA EG++ + + L++ Sbjct: 194 NNQGLTPFKLAGVEGNIVMFQHLMQK 219 >6BOA-A nrPDB Length = 742 Score = 74.6 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 38/177 (21%), Positives = 67/177 (37%), Gaps = 25/177 (14%) Query: 5 WGNELASAAARGDLEQLTSLLQNN-VNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGAN 62 W + L AA D++ L LL+ V+ + G TAL + N E A L+ Sbjct: 45 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 104 Query: 63 PDLKDRT-----GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGN 104 + T G +H A ++ ++ LL +A V+ G Sbjct: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGE 164 Query: 105 LPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRN----EVVSLMQ 157 PL AA +V L++H A ++ ++ G+T + L ++ +L+ Sbjct: 165 HPLSFAACVNSEEIVRLLIEHGA-DIRAQDSLGNTVLHILILQPNKTFACQMYNLLL 220 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 29/141 (20%), Positives = 47/141 (33%), Gaps = 19/141 (13%) Query: 40 TALQVMKLGNPEIA--RRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQAD-- 95 + L + N A + L + G +H AA L+ L+E + Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 96 ---VNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN----------VGHRNH--KGDTA 140 + E EG LH+A ++ +V L+ AS N G+ Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHP 166 Query: 141 CDLARLYGRNEVVSLMQANGA 161 A E+V L+ +GA Sbjct: 167 LSFAACVNSEEIVRLLIEHGA 187 Score = 60.0 bits (144), Expect = 5e-10, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 37/96 (38%), Gaps = 5/96 (5%) Query: 72 AVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 + + AA+ + L LL++ V+ G LH+AA +L L++ V Sbjct: 47 SPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPELV 106 Query: 131 GHRNH----KGDTACDLARLYGRNEVVSLMQANGAG 162 +G TA +A + +V + A A Sbjct: 107 FEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 142 Score = 55.0 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 54/146 (36%), Gaps = 33/146 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG-------------FGRTALQ-VMKLGNPEIAR 54 L A ++ + +LL +V+A+ FG L + + EI R Sbjct: 121 LHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVR 180 Query: 55 RLLLRGANPDLKDRTGFAVIH---------DAARAGFLDTLQTLLEFQADVN------IE 99 L+ GA+ +D G V+H A + L L + + + Sbjct: 181 LLIEHGADIRAQDSLGNTVLHILILQPNKTFACQMYNL----LLSYDRHGDHLQPLDLVP 236 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKH 125 +++G P LA EG+ + + L++ Sbjct: 237 NHQGLTPFKLAGVEGNTVMFQHLMQK 262 >4BSZ-B nrPDB Length = 202 Score = 72.7 bits (177), Expect = 8e-14, Method: Composition-based stats. Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 15/130 (11%) Query: 45 MKLGNPEIARRLLLRGANPDL-----KDRTGFAVIHDAARAGFLDTLQTLLE-------- 91 + G+ + + + +P+L + + +H AA G ++T++ +LE Sbjct: 22 ARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETVSRANSA 81 Query: 92 --FQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGR 149 +A VN + GN LH A+ G L VV+ L ++ RN G A A G+ Sbjct: 82 EDLKAFVNEVNKTGNTALHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIFEAENSGK 141 Query: 150 NEVVSLMQAN 159 EV + Sbjct: 142 EEVETYFLKK 151 Score = 54.2 bits (129), Expect = 2e-08, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 12/103 (11%) Query: 2 AEPWGNELASAAARGDLEQLTSLLQ--NNVN--------VNAQNGFGRTALQVMKL-GNP 50 +E L AAA G +E + +L+ + N VN N G TAL L G Sbjct: 49 SESDSTALHMAAANGHIETVRYILETVSRANSAEDLKAFVNEVNKTGNTALHWASLNGKL 108 Query: 51 EIARRLL-LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF 92 ++ + L A+P ++++ G I +A +G + L+ Sbjct: 109 DVVKLLCDEYEADPFIRNKFGHDAIFEAENSGKEEVETYFLKK 151 >3LVQ-E nrPDB Length = 497 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 63 PDLKDRTGFAVIHDA---ARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119 PD + +H A A L + +++ ++ + +GN LH AA + Sbjct: 165 PDAQAPEELV-LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 223 Query: 120 EFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 + L+K + VG N G+TA D+AR E L++ AG Sbjct: 224 KLLLK-GRALVGTVNEAGETALDIARKKHHKECEELLEQAQAG 265 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 46/140 (32%), Gaps = 16/140 (11%) Query: 4 PWGNELASAAARGDLEQLTSLLQNNVN---------VNAQNGFGRTALQVMK----LGNP 50 P L +A DL + N + A L + + Sbjct: 131 PEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL---VLHLAVKVANQASL 187 Query: 51 EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 + ++ G + D K G +H AA D L+ LL+ +A V + G L +A Sbjct: 188 PLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIA 247 Query: 111 AKEGHLRVVEFLVKHTASNV 130 K+ H E L + A Sbjct: 248 RKKHHKECEELLEQAQAGTF 267 >6DVZ-A nrPDB Length = 791 Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 61/176 (34%), Gaps = 45/176 (25%) Query: 12 AAARGDLEQLTSLLQNNVNV-------NAQN---------GFGRTALQVMKLG----NPE 51 A + G +E+L LLQ+ ++ + + G+T L L E Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNINPNTKE 185 Query: 52 IARRLLLRGANPDLKDR-----------TGFAVIHDAARAGFLDTLQTLLEFQADVNIED 100 I R LL D+ DR G ++ A D L+ ADVN Sbjct: 186 IVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAHA 245 Query: 101 N--------------EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142 G PL LAA +V+ L+++ +++ ++ +G+ Sbjct: 246 KGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNILH 301 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 30/140 (21%) Query: 14 ARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIARRLLL 58 +GD+ + L+ +VNA FG T L + PEI + L+ Sbjct: 226 RQGDITAV--LIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME 283 Query: 59 R-GANPDLKDRTGFAVIH-DAARAGFLDTLQTLLEFQADV-----------NIEDNEGNL 105 + +D G ++H A T ++ D+ + +N+G Sbjct: 284 NEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLT 343 Query: 106 PLHLAAKEGHLRVVEFLVKH 125 PL LAAK G ++++++ Sbjct: 344 PLQLAAKMGKAEILKYILSR 363 >4N5Q-A nrPDB Length = 257 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 36/181 (19%), Positives = 63/181 (34%), Gaps = 45/181 (24%) Query: 7 NELASAAARGDLEQLTSLLQNNVNV-------NAQN---------GFGRTALQVMKLG-- 48 + +A + G +E+L LLQ+ ++ + + G+T L L Sbjct: 5 KRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDTGKTCLMKALLNIN 64 Query: 49 --NPEIARRLLLRGANPDLKDR-----------TGFAVIHDAARAGFLDTLQTLLEFQAD 95 EI R LL D+ DR G ++ A D L+ AD Sbjct: 65 PNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGAD 124 Query: 96 VNIEDN--------------EGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTAC 141 VN G PL LAA +V+ L+++ +++ ++ +G+ Sbjct: 125 VNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGNNIL 184 Query: 142 D 142 Sbjct: 185 H 185 Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 53/140 (37%), Gaps = 30/140 (21%) Query: 14 ARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIARRLLL 58 +GD+ + L+ +VNA FG T L + PEI + L+ Sbjct: 110 RQGDITAV--LIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLME 167 Query: 59 R-GANPDLKDRTGFAVIH-DAARAGFLDTLQTLLEFQADV-----------NIEDNEGNL 105 + +D G ++H A T ++ D+ + +N+G Sbjct: 168 NEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRNNDGLT 227 Query: 106 PLHLAAKEGHLRVVEFLVKH 125 PL LAAK G ++++++ Sbjct: 228 PLQLAAKMGKAEILKYILSR 247 >2B0O-E nrPDB Length = 301 Score = 62.7 bits (151), Expect = 7e-11, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 5/103 (4%) Query: 63 PDLKDRTGFAVIHDA---ARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVV 119 PD + +H A A L + +++ ++ + +GN LH AA + Sbjct: 184 PDAQAPEELV-LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCL 242 Query: 120 EFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 + L+K + VG N G+TA D+AR E L++ AG Sbjct: 243 KLLLK-GRALVGTVNEAGETALDIARKKHHKECEELLEQAQAG 284 Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 29/140 (20%), Positives = 46/140 (32%), Gaps = 16/140 (11%) Query: 4 PWGNELASAAARGDLEQLTSLLQNNVN---------VNAQNGFGRTALQVMK----LGNP 50 P L +A DL + N + A L + + Sbjct: 150 PEPQRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEEL---VLHLAVKVANQASL 206 Query: 51 EIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 110 + ++ G + D K G +H AA D L+ LL+ +A V + G L +A Sbjct: 207 PLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIA 266 Query: 111 AKEGHLRVVEFLVKHTASNV 130 K+ H E L + A Sbjct: 267 RKKHHKECEELLEQAQAGTF 286 >1DCQ-A nrPDB Length = 278 Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 56/153 (36%), Gaps = 12/153 (7%) Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFA 72 A + + L V ++ FG LQ G + L G PD Sbjct: 120 ARKKHADTAAKLHSLCEAVKTRDIFG--LLQAYADGVDLTEKIPLANGHEPD------ET 171 Query: 73 VIHDAARAGF---LDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129 +H A R+ L + L++ +++ + +G+ LH + ++ L+ ++ Sbjct: 172 ALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLL-RGKAS 230 Query: 130 VGHRNHKGDTACDLARLYGRNEVVSLMQANGAG 162 + N G+T D+A+ L+ +G Sbjct: 231 IEIANESGETPLDIAKRLKHEHCEELLTQALSG 263 Score = 59.6 bits (143), Expect = 7e-10, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 42/128 (32%), Gaps = 10/128 (7%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLG----NPEIARRLLLRGANPD 64 L A A G L N + TAL + + I L+ N D Sbjct: 146 LLQAYADGVDLTEKIPLANGHEPDE------TALHLAVRSVDRTSLHIVDFLVQNSGNLD 199 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVK 124 + G +H + L+ LL +A + I + G PL +A + H E L + Sbjct: 200 KQTGKGSTALHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQ 259 Query: 125 HTASNVGH 132 + Sbjct: 260 ALSGRFNS 267 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 46/123 (37%), Gaps = 15/123 (12%) Query: 44 VMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTL-LEFQADVNIEDNE 102 + + + A +L +D G A A +D + + L + + Sbjct: 119 YARKKHADTAAKLHSLCEAVKTRDIFGL----LQAYADGVDLTEKIPLANGHEPDE---- 170 Query: 103 GNLPLHLAAK---EGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQAN 159 LHLA + L +V+FLV++ + N+ + KG TA L E + L+ Sbjct: 171 --TALHLAVRSVDRTSLHIVDFLVQN-SGNLDKQTGKGSTALHYCCLTDNAECLKLLLRG 227 Query: 160 GAG 162 A Sbjct: 228 KAS 230 >6CUD-A nrPDB Length = 806 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 52/146 (35%), Gaps = 31/146 (21%) Query: 42 LQVMKLGNPEIARRLLLRG--ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 L + GN + R++L N + D G + A L+ + LL+ + I Sbjct: 32 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 91 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTA------------------SNVGHRNHKGD--- 138 D L LA +G++R+VE ++ H + + G Sbjct: 92 D-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFS 146 Query: 139 ---TACDLARLYGRNEVVSLMQANGA 161 T LA + EVV ++ GA Sbjct: 147 PDITPIILAAHCQKYEVVHMLLMKGA 172 Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 54/149 (36%), Gaps = 31/149 (20%) Query: 7 NELASAAARGDLEQLTSLLQNN--VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 AA G++ + +L+ + +NVN + G+ ALQ+ LLL+ N Sbjct: 29 ERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 88 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEF---QADVNIE----------------DNEGN- 104 R G A++ A G++ ++ +L A + D +G Sbjct: 89 ---RIGDALL-LAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTR 144 Query: 105 -----LPLHLAAKEGHLRVVEFLVKHTAS 128 P+ LAA VV L+ A Sbjct: 145 FSPDITPIILAAHCQKYEVVHMLLMKGAR 173 >5IRX-A nrPDB Length = 636 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 63/175 (36%), Gaps = 39/175 (22%) Query: 7 NELASAAARGDLEQLTSLL-------QNNVNVNAQN-GFGRTALQVMKL----GNPEIAR 54 + A A+ + ++L SLL + + ++ G+T L L G + Sbjct: 10 RSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTIA 69 Query: 55 RLLLRGANPDLKDRT-----------GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100 LL D + G +H A + + L+E ADV Sbjct: 70 LLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGD 129 Query: 101 -----------NEGNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142 G LPL LAA L +V+FL++++ +++ R+ G+T Sbjct: 130 FFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 184 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 35/168 (20%), Positives = 62/168 (36%), Gaps = 35/168 (20%) Query: 25 LQNNVNVNAQNGF--GRTALQVM-KLGNPEIARRLLLRGANPDLKDRT------------ 69 L+ VN + + + G+TAL + + N + L+ GA+ Sbjct: 81 LKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGF 140 Query: 70 --GFAVIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAKE-----GHLRVV 119 G + AA L ++ LL+ AD++ D+ GN LH + + + V Sbjct: 141 YFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFV 200 Query: 120 -----EFLVKHTASNVGHR-----NHKGDTACDLARLYGRNEVVSLMQ 157 E L+ + + N KG T LA G+ V++ + Sbjct: 201 TSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYIL 248 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 56/151 (37%), Gaps = 34/151 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53 L A R ++ +T L++N +V A FG L + I Sbjct: 100 LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIV 159 Query: 54 RRLLL---RGANPDLKDRTGFAVIH--DAARAGFLDTLQT-------LLEFQADVN---- 97 + LL + A+ +D G V+H +D + +L A ++ Sbjct: 160 KFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLK 219 Query: 98 ---IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I + +G PL LAA G + V+ ++++ Sbjct: 220 LEEITNRKGLTPLALAASSGKIGVLAYILQR 250 Score = 32.6 bits (73), Expect = 0.081, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 25/81 (30%), Gaps = 14/81 (17%) Query: 95 DVNIED-NEGNLPLHLA---AKEGHLRVVEFLVKHTASNVGHRNH----------KGDTA 140 D +D G L A G + L+ + KG TA Sbjct: 40 DSEFKDPETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTA 99 Query: 141 CDLARLYGRNEVVSLMQANGA 161 +A +V+L+ NGA Sbjct: 100 LHIAIERRNMTLVTLLVENGA 120 >6CV9-A nrPDB Length = 842 Score = 60.0 bits (144), Expect = 5e-10, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 51/146 (34%), Gaps = 31/146 (21%) Query: 42 LQVMKLGNPEIARRLLL--RGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 L + GN + R++L N + D G + A L+ + LL+ + + Sbjct: 14 LDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKKENLSRVG 73 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTA------------------SNVGHRNHKGD--- 138 D L LA +G++R+VE ++ H A + + G Sbjct: 74 D-----ALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGTRFS 128 Query: 139 ---TACDLARLYGRNEVVSLMQANGA 161 T LA E+V + GA Sbjct: 129 HDVTPIILAAHCQEYEIVHTLLRKGA 154 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 58/150 (38%), Gaps = 33/150 (22%) Query: 7 NELASAAARGDLEQLTSLLQ--NNVNVNAQNGFGRTALQVMKLG-NPEIARRLLLRGANP 63 AA G++ + +L+ +++NVN + G+ ALQ+ + EI LL + Sbjct: 11 ERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEITELLLKK---- 66 Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQA-------------------DVNIEDNEGN 104 + R G A++ A G++ ++ +L A D D +G Sbjct: 67 ENLSRVGDALL-LAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQDDFYAYDEDGT 125 Query: 105 ------LPLHLAAKEGHLRVVEFLVKHTAS 128 P+ LAA +V L++ A Sbjct: 126 RFSHDVTPIILAAHCQEYEIVHTLLRKGAR 155 >6DJS-A nrPDB Length = 676 Score = 59.6 bits (143), Expect = 6e-10, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 52/146 (35%), Gaps = 31/146 (21%) Query: 42 LQVMKLGNPEIARRLLLRG--ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 L + GN + R++L N + D G + A L+ + LL+ + I Sbjct: 49 LDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLARIG 108 Query: 100 DNEGNLPLHLAAKEGHLRVVEFLVKHTA------------------SNVGHRNHKGD--- 138 D L LA +G++R+VE ++ H + + G Sbjct: 109 D-----ALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTRFS 163 Query: 139 ---TACDLARLYGRNEVVSLMQANGA 161 T LA + EVV ++ GA Sbjct: 164 PDITPIILAAHCQKYEVVHMLLMKGA 189 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 54/149 (36%), Gaps = 31/149 (20%) Query: 7 NELASAAARGDLEQLTSLLQNN--VNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPD 64 AA G++ + +L+ + +NVN + G+ ALQ+ LLL+ N Sbjct: 46 ERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTELLLKKENLA 105 Query: 65 LKDRTGFAVIHDAARAGFLDTLQTLLEF---QADVNIE----------------DNEGN- 104 R G A++ A G++ ++ +L A + D +G Sbjct: 106 ---RIGDALL-LAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDDFYAYDEDGTR 161 Query: 105 -----LPLHLAAKEGHLRVVEFLVKHTAS 128 P+ LAA VV L+ A Sbjct: 162 FSPDITPIILAAHCQKYEVVHMLLMKGAR 190 >6OO7-A nrPDB Length = 786 Score = 58.8 bits (141), Expect = 1e-09, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 60/150 (40%), Gaps = 33/150 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNA----------QNG---FGRTALQVM-KLGNPEIAR 54 L A + L+ + L++N NV+A Q+ FG L + ++ Sbjct: 166 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 225 Query: 55 RLLL---RGANPDLKDRTGFAVIH------DAARAGFLDTLQT---LLEFQADVN----- 97 LL + A+ +D G V+H D + ++ LL+ A + Sbjct: 226 YLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDGLLQAGARLCPNVQL 285 Query: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I + EG PL LAAKEG + + + +++ Sbjct: 286 EGIPNLEGLTPLKLAAKEGKIEIFKHILQR 315 Score = 55.3 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 39/164 (23%), Positives = 60/164 (36%), Gaps = 35/164 (21%) Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDL----------KDR---TGFA 72 VN + + G +AL + + + + L+ GAN +D G Sbjct: 151 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 210 Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121 + AA D + LLE A + +D+ GN LH E VV Sbjct: 211 PLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYD 270 Query: 122 -LVKHTAS---NV---GHRNHKGDTACDLARLYGRNEVVS-LMQ 157 L++ A NV G N +G T LA G+ E+ ++Q Sbjct: 271 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQ 314 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 64/174 (36%), Gaps = 38/174 (21%) Query: 7 NELASAAARGDLEQLTSLLQNN-------VNVNAQNGF-GRTALQVM----KLGNPEIAR 54 + L + ARG+ E L LL+ + G G+T L + G + Sbjct: 76 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 135 Query: 55 RLLL----RG-----ANPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100 LL G N D G + +H A L ++ L+E A+V+ + Sbjct: 136 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 195 Query: 101 ----------NEGNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142 G LPL LAA VV +L+++ +++ ++ G+T Sbjct: 196 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLH 249 Score = 33.4 bits (75), Expect = 0.047, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 40/109 (36%), Gaps = 21/109 (19%) Query: 74 IHDAARAGFLDTLQTLLEF--QADVNIEDNE------GNLPLHLAA---KEGHLRVVEFL 122 + + G + L LLE+ + + D+E G L A ++G ++ L Sbjct: 78 LFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQPL 137 Query: 123 VK------HTASNVGHRNHK----GDTACDLARLYGRNEVVSLMQANGA 161 ++ + V + G +A +A + V L+ NGA Sbjct: 138 LEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGA 186 >2NYJ-A nrPDB Length = 273 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 63/175 (36%), Gaps = 39/175 (22%) Query: 7 NELASAAARGDLEQLTSLL-------QNNVNVNAQN-GFGRTALQVMKL----GNPEIAR 54 + A A+ + ++L SLL + + ++ G+T L L G + Sbjct: 15 RSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLNLHNGQNDTIA 74 Query: 55 RLLLRGANPDLKDRT-----------GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100 LL D + G +H A + + L+E ADV Sbjct: 75 LLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGD 134 Query: 101 -----------NEGNLPLHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142 G LPL LAA L +V+FL++++ +++ R+ G+T Sbjct: 135 FFKKTKGRPGFYFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLH 189 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 35/168 (20%), Positives = 62/168 (36%), Gaps = 35/168 (20%) Query: 25 LQNNVNVNAQNGF--GRTALQVM-KLGNPEIARRLLLRGANPDLKDRT------------ 69 L+ VN + + + G+TAL + + N + L+ GA+ Sbjct: 86 LKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGF 145 Query: 70 --GFAVIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAKE-----GHLRVV 119 G + AA L ++ LL+ AD++ D+ GN LH + + + V Sbjct: 146 YFGELPLSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFV 205 Query: 120 -----EFLVKHTASNVGHR-----NHKGDTACDLARLYGRNEVVSLMQ 157 E L+ + + N KG T LA G+ V++ + Sbjct: 206 TSMYNEILILGAKLHPTLKLEEITNRKGLTPLALAASSGKIGVLAYIL 253 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 56/151 (37%), Gaps = 34/151 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53 L A R ++ +T L++N +V A FG L + I Sbjct: 105 LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIV 164 Query: 54 RRLLL---RGANPDLKDRTGFAVIH--DAARAGFLDTLQT-------LLEFQADVN---- 97 + LL + A+ +D G V+H +D + +L A ++ Sbjct: 165 KFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNEILILGAKLHPTLK 224 Query: 98 ---IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I + +G PL LAA G + V+ ++++ Sbjct: 225 LEEITNRKGLTPLALAASSGKIGVLAYILQR 255 Score = 31.8 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 22/74 (29%), Gaps = 13/74 (17%) Query: 101 NEGNLPLHLA---AKEGHLRVVEFLVKHTASNVGHRNH----------KGDTACDLARLY 147 G L A G + L+ + KG TA +A Sbjct: 52 ETGKTCLLKAMLNLHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIER 111 Query: 148 GRNEVVSLMQANGA 161 +V+L+ NGA Sbjct: 112 RNMTLVTLLVENGA 125 >5UIL-A nrPDB Length = 405 Score = 58.4 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 23/124 (18%), Positives = 55/124 (44%), Gaps = 5/124 (4%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65 E+ A D + + L++ + +N +G + + V GN E+ + L+ +GAN + Sbjct: 280 KEILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANIND 339 Query: 66 KDRTGFAVIH----DAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 ++ G V ++G L+ L++ D+ + D + K G+ ++++ Sbjct: 340 RNYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQY 399 Query: 122 LVKH 125 ++ Sbjct: 400 MMAF 403 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 21/121 (17%), Positives = 51/121 (42%), Gaps = 5/121 (4%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101 L+ K + + +L+ + K+ G++ + AA G ++ ++ L+ A++N + Sbjct: 283 LEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANINDRNY 342 Query: 102 EGNL-PLHLA---AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQ 157 +G ++ K G ++ L+ ++ ++K T D G ++ M Sbjct: 343 KGTTVAMYFKDYMLKSGDYSGLKMLIDLG-LDLTLTDYKDYTVFDYLEKSGNKNLLQYMM 401 Query: 158 A 158 A Sbjct: 402 A 402 Score = 31.5 bits (70), Expect = 0.17, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 + + A K + + L+ S + +N G + +A +G E++ + + G Sbjct: 276 KDNFKEILEACKYSDSKYIAKLI-RAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKG 334 Query: 161 A 161 A Sbjct: 335 A 335 >5AN8-A nrPDB Length = 613 Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 57/150 (38%), Gaps = 33/150 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNA----------QNG---FGRTALQVM-KLGNPEIAR 54 L A + L+ + L++N NV+A Q+ FG L + ++ Sbjct: 91 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 150 Query: 55 RLLLRG---ANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADVN----- 97 LL A+ +D G V+H ++ LL+ A + Sbjct: 151 YLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDGLLQAGARLCPNVQL 210 Query: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I + EG PL LAAKEG + + + +++ Sbjct: 211 EGIPNLEGLTPLKLAAKEGKIEIFKHILQR 240 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 45/209 (21%), Positives = 74/209 (35%), Gaps = 47/209 (22%) Query: 7 NELASAAARGDLEQLTSLLQNN-------VNVNAQNGF-GRTALQVM----KLGNPEIAR 54 + L + ARG+ E L LL+ + G G+T L + G + Sbjct: 1 DRLFNVVARGNPEDLAGLLEYLRRTSKYLTDSEYTEGSTGKTCLMKAVLNLQDGVNACIQ 60 Query: 55 RLLL----RG-----ANPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED--- 100 LL G N D G + +H A L ++ L+E A+V+ + Sbjct: 61 PLLEIDRDSGNPQPLVNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGH 120 Query: 101 ----------NEGNLPLHLAAKEGHLRVVEFLV--KHTASNVGHRNHKGDTACD-LARLY 147 G LPL LAA VV +L+ H A+++ ++ G+T L + Sbjct: 121 FFQKNQDTCFYFGELPLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIA 180 Query: 148 GRN--------EVVSLMQANGAGGATNLQ 168 + + + GA N+Q Sbjct: 181 DNSPENSALVVRMYDGLLQAGARLCPNVQ 209 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 39/164 (23%), Positives = 60/164 (36%), Gaps = 35/164 (21%) Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDL----------KDR---TGFA 72 VN + + G +AL + + + + L+ GAN +D G Sbjct: 76 VNAQCTDEYYRGHSALHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGEL 135 Query: 73 VIHDAARAGFLDTLQTLLEF---QADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121 + AA D + LLE A + +D+ GN LH E VV Sbjct: 136 PLSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYD 195 Query: 122 -LVKHTAS---NV---GHRNHKGDTACDLARLYGRNEVVS-LMQ 157 L++ A NV G N +G T LA G+ E+ ++Q Sbjct: 196 GLLQAGARLCPNVQLEGIPNLEGLTPLKLAAKEGKIEIFKHILQ 239 >6BO5-A nrPDB Length = 695 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 35/164 (21%) Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDLKDRT-------------GFA 72 VN + F G +AL + + + + L+ GA+ L+ G Sbjct: 113 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 172 Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121 + AA D + LLE A + D+ GN LH E V+ Sbjct: 173 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 232 Query: 122 -LVKHTASNV------GHRNHKGDTACDLARLYGRNEVVS-LMQ 157 L++ A NH+G T LA G+ E+ ++Q Sbjct: 233 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 276 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 53/151 (35%), Gaps = 35/151 (23%) Query: 9 LASAAARGDLEQLTSLLQNNVNVN-------AQNGFGRTALQ--------VMKLGNPEIA 53 L A + L+ + L++N +V+ Q G T ++ Sbjct: 128 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQG-TCFYFGELPLSLAACTKQWDVV 186 Query: 54 RRLLL---RGANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADV----- 96 LL + A+ + D G V+H + LL+ A + Sbjct: 187 TYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 246 Query: 97 --NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I +++G PL LAAKEG + + +++ Sbjct: 247 LEEISNHQGLTPLKLAAKEGKIEIFRHILQR 277 Score = 31.8 bits (71), Expect = 0.13, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 13/72 (18%) Query: 103 GNLPLHLAA---KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGR 149 G L A ++G + L++ + V + G +A +A Sbjct: 77 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRS 136 Query: 150 NEVVSLMQANGA 161 + V L+ NGA Sbjct: 137 LQCVKLLVENGA 148 >5HI9-A nrPDB Length = 770 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 35/164 (21%) Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDLKDRT-------------GFA 72 VN + F G +AL + + + + L+ GA+ L+ G Sbjct: 153 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 212 Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121 + AA D + LLE A + D+ GN LH E V+ Sbjct: 213 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 272 Query: 122 -LVKHTASNV------GHRNHKGDTACDLARLYGRNEVVS-LMQ 157 L++ A NH+G T LA G+ E+ ++Q Sbjct: 273 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 316 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 53/151 (35%), Gaps = 35/151 (23%) Query: 9 LASAAARGDLEQLTSLLQNNVNVN-------AQNGFGRTALQ--------VMKLGNPEIA 53 L A + L+ + L++N +V+ Q G T ++ Sbjct: 168 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQG-TCFYFGELPLSLAACTKQWDVV 226 Query: 54 RRLLL---RGANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADV----- 96 LL + A+ + D G V+H + LL+ A + Sbjct: 227 TYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 286 Query: 97 --NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I +++G PL LAAKEG + + +++ Sbjct: 287 LEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 Score = 31.8 bits (71), Expect = 0.13, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 13/72 (18%) Query: 103 GNLPLHLAA---KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGR 149 G L A ++G + L++ + V + G +A +A Sbjct: 117 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRS 176 Query: 150 NEVVSLMQANGA 161 + V L+ NGA Sbjct: 177 LQCVKLLVENGA 188 >6G1K-A nrPDB Length = 921 Score = 53.4 bits (127), Expect = 4e-08, Method: Composition-based stats. Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 26/138 (18%) Query: 10 ASAAARGDLEQLTSLLQNN-----VNVNAQNGFGRTALQVMKLG-NPEIARRLLLRGANP 63 SA +GD + L+ +N+N + GRTAL + N EI LL N Sbjct: 37 LSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLS--FNV 94 Query: 64 DLKDRTGFAVIHDAARAGFLDTLQTLLEFQ------------ADVNIEDNEGN-LPLHLA 110 + G A++H A R + ++ LL + D D + P+ LA Sbjct: 95 YV----GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPIILA 149 Query: 111 AKEGHLRVVEFLVKHTAS 128 A + +++ LV+ S Sbjct: 150 AHTNNYEIIKMLVQKGVS 167 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 47/139 (33%), Gaps = 24/139 (17%) Query: 39 RTALQVMKLGNPEIARRLLLRGA-----NPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ 93 ++ L ++ G+ + L N + D G + A L+ ++ LL F Sbjct: 34 KSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFN 93 Query: 94 ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTAS-------NVGHRNHKGD-----TAC 141 V G+ LH A ++ + VE L+ H + D T Sbjct: 94 VYV------GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSDFTPDITPI 146 Query: 142 DLARLYGRNEVVSLMQANG 160 LA E++ ++ G Sbjct: 147 ILAAHTNNYEIIKMLVQKG 165 >6C8G-A nrPDB Length = 675 Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 38/98 (38%), Gaps = 17/98 (17%) Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115 G +H A ++ L+E ADV+ + G LPL LAA Sbjct: 103 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 162 Query: 116 LRVVEFLVK--HTASNVGHRNHKGDTACD-LARLYGRN 150 +V +L + H +++ ++ +G+T L + Sbjct: 163 PDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNT 200 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 51/151 (33%), Gaps = 33/151 (21%) Query: 37 FGRTALQVMKLGNPE-IARRLLLRGANPDLK---------DRTGF-----AVIHDAARAG 81 G+TAL + + L+ +GA+ + D G+ + AA Sbjct: 102 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 161 Query: 82 FLDTLQTLLEF---QADVNIEDNEGNLPLH--LAAKEGHLRVVEFLVKHTASNVGHR--- 133 D + L E +AD+ +D+ GN LH +A + +F+ K V Sbjct: 162 QPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKL 221 Query: 134 ----------NHKGDTACDLARLYGRNEVVS 154 N+ + +A G+ + Sbjct: 222 YPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQ 252 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 57/160 (35%), Gaps = 34/160 (21%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53 L A R + L++ +V+AQ FG L + P+I Sbjct: 107 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 166 Query: 54 RRLLLRG---ANPDLKDRTGFAVIH-DAARAGF-----------LDTLQT-LLEFQADVN 97 L A+ +D G V+H A A D L ++ D + Sbjct: 167 HYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSS 226 Query: 98 IE---DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRN 134 +E +N+ PL +AAK G + + + +++ + R+ Sbjct: 227 LEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARH 266 Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 25/74 (33%), Gaps = 15/74 (20%) Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146 G LH+A + VE LV+ A +V + G+ LA Sbjct: 101 YRGQTALHIAIERRCKHYVELLVEKGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 159 Query: 147 YGRNEVVSLMQANG 160 + ++V + N Sbjct: 160 TNQPDIVHYLTENA 173 >6BBJ-A nrPDB Length = 868 Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 38/98 (38%), Gaps = 17/98 (17%) Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115 G +H A ++ L+E ADV+ + G LPL LAA Sbjct: 234 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 293 Query: 116 LRVVEFLVK--HTASNVGHRNHKGDTACD-LARLYGRN 150 +V +L + H +++ ++ +G+T L + Sbjct: 294 PDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNT 331 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 51/151 (33%), Gaps = 33/151 (21%) Query: 37 FGRTALQVMKLGNPE-IARRLLLRGANPDLK---------DRTGF-----AVIHDAARAG 81 G+TAL + + L+ +GA+ + D G+ + AA Sbjct: 233 RGQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTN 292 Query: 82 FLDTLQTLLEF---QADVNIEDNEGNLPLH--LAAKEGHLRVVEFLVKHTASNVGHR--- 133 D + L E +AD+ +D+ GN LH +A + +F+ K V Sbjct: 293 QPDIVHYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKL 352 Query: 134 ----------NHKGDTACDLARLYGRNEVVS 154 N+ + +A G+ + Sbjct: 353 YPDSSLEAIFNNDSMSPLMMAAKLGKIGIFQ 383 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 57/160 (35%), Gaps = 34/160 (21%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53 L A R + L++ +V+AQ FG L + P+I Sbjct: 238 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 297 Query: 54 RRLLLRG---ANPDLKDRTGFAVIH-DAARAGF-----------LDTLQT-LLEFQADVN 97 L A+ +D G V+H A A D L ++ D + Sbjct: 298 HYLTENAHKKADIRRQDSRGNTVLHALVAIADNTRENTKFVTKVYDLLVIKCVKLYPDSS 357 Query: 98 IE---DNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRN 134 +E +N+ PL +AAK G + + + +++ + R+ Sbjct: 358 LEAIFNNDSMSPLMMAAKLGKIGIFQHIIRLEIKDEEARH 397 Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 25/74 (33%), Gaps = 15/74 (20%) Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146 G LH+A + VE LV+ A +V + G+ LA Sbjct: 232 YRGQTALHIAIERRCKHYVELLVEKGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 290 Query: 147 YGRNEVVSLMQANG 160 + ++V + N Sbjct: 291 TNQPDIVHYLTENA 304 >2ETB-A nrPDB Length = 256 Score = 53.0 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 36/164 (21%), Positives = 57/164 (34%), Gaps = 35/164 (21%) Query: 29 VNVNAQNGF--GRTALQVMKLG-NPEIARRLLLRGANPDLKDRT-------------GFA 72 VN + F G +AL + + + + L+ GA+ L+ G Sbjct: 79 VNAQCTDEFYQGHSALHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGEL 138 Query: 73 VIHDAARAGFLDTLQTLLEFQ---ADVNIEDNEGNLPLHLAAK------EGHLRVVEF-- 121 + AA D + LLE A + D+ GN LH E V+ Sbjct: 139 PLSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYD 198 Query: 122 -LVKHTASNV------GHRNHKGDTACDLARLYGRNEVVS-LMQ 157 L++ A NH+G T LA G+ E+ ++Q Sbjct: 199 GLLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQ 242 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 55/150 (36%), Gaps = 33/150 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQN-------------GFGRTALQVM-KLGNPEIAR 54 L A + L+ + L++N +V+ + FG L + ++ Sbjct: 94 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 153 Query: 55 RLLL---RGANPDLKDRTGFAVIHDAAR------AGFLDTLQT---LLEFQADV------ 96 LL + A+ + D G V+H + LL+ A + Sbjct: 154 YLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQL 213 Query: 97 -NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I +++G PL LAAKEG + + +++ Sbjct: 214 EEISNHQGLTPLKLAAKEGKIEIFRHILQR 243 Score = 30.7 bits (68), Expect = 0.35, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 25/72 (34%), Gaps = 13/72 (18%) Query: 103 GNLPLHLAA---KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGR 149 G L A ++G + L++ + V + G +A +A Sbjct: 43 GKTCLMKAVLNLQDGVNACIMPLLQIDKDSGNPKPLVNAQCTDEFYQGHSALHIAIEKRS 102 Query: 150 NEVVSLMQANGA 161 + V L+ NGA Sbjct: 103 LQCVKLLVENGA 114 >2F37-A nrPDB Length = 251 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 39/98 (39%), Gaps = 17/98 (17%) Query: 62 NPDLKDRT--GFAVIHDAARAGFLDTLQTLLEFQADVNIED-------------NEGNLP 106 N D G + +H A L ++ L+E A+V+ G LP Sbjct: 85 NAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELP 144 Query: 107 LHLAAKEGHLRVVEFLVKHT--ASNVGHRNHKGDTACD 142 L LAA VV +L+++ +++ + +G+T Sbjct: 145 LSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLH 182 Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 52/150 (34%), Gaps = 33/150 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQN-------------GFGRTALQVM-KLGNPEIAR 54 L A + L+ + L++N NV+A+ FG L + ++ Sbjct: 99 LHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVS 158 Query: 55 RLLL---RGANPDLKDRTGFAVIHDAARAGFLDTLQT---------LLEFQADVN----- 97 LL + A+ D G V+H LL+ A + Sbjct: 159 YLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQL 218 Query: 98 --IEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 I + + PL LAAKEG + + +++ Sbjct: 219 EDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 14/72 (19%) Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRN-------------HKGDTACDLARLY 147 G+ LH+A ++ L+ V+ LV++ A NV R + G+ LA Sbjct: 93 YRGHSALHIAIEKRSLQCVKLLVENGA-NVHARACGRFFQKGQGTCFYFGELPLSLAACT 151 Query: 148 GRNEVVSLMQAN 159 + +VVS + N Sbjct: 152 KQWDVVSYLLEN 163 Score = 30.3 bits (67), Expect = 0.40, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 44/122 (36%), Gaps = 24/122 (19%) Query: 61 ANPDLKDRTGFAVIHDAARAGFLDTLQTLLEF--QADVNIEDNE------GNLPLHLAA- 111 +P+ DR + +A G + L L E+ + + D+E G L A Sbjct: 1 PDPNRFDRDR---LFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVL 57 Query: 112 --KEGHLRVVEFLVK------HTASNVGHRNHK----GDTACDLARLYGRNEVVSLMQAN 159 K+G + L++ + V + G +A +A + V L+ N Sbjct: 58 NLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVEN 117 Query: 160 GA 161 GA Sbjct: 118 GA 119 >4XD0-A nrPDB Length = 417 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 47/104 (45%), Gaps = 5/104 (4%) Query: 7 NELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKL-GNPEIARRLLLRGANPDL 65 +E+ +A E ++ LL+ + +N G + + + GN ++ L+ +G N + Sbjct: 293 DEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNIND 352 Query: 66 KDRTGFAVIH----DAARAGFLDTLQTLLEFQADVNIEDNEGNL 105 ++ G V R+G L+ L+ D+ ++DNEG Sbjct: 353 RNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLS 396 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 52/119 (43%), Gaps = 5/119 (4%) Query: 42 LQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN 101 L + +PE +LL K+ G++ I AA G +D ++ L+ ++N + Sbjct: 296 LTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNINDRNY 355 Query: 102 EGNL-PLHLA---AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLM 156 +G ++ + G+ +E L+ ++ ++++G + D R E+ + M Sbjct: 356 KGTTVAMYFKDYMLRSGNYTGLENLINLG-LDLFLKDNEGLSVFDYMRKNKNIELFNFM 413 Score = 33.0 bits (74), Expect = 0.059, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 110 AAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANG 160 A ++ + L+K T + + +NH G + +A +G +V+ + + G Sbjct: 298 ACEDKSPEFISKLLK-TENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKG 347 >3W9G-A nrPDB Length = 260 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 38/98 (38%), Gaps = 17/98 (17%) Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115 G +H A ++ L+E ADV+ + G LPL LAA Sbjct: 93 GQTALHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 152 Query: 116 LRVVEFLVKHT--ASNVGHRNHKGDTACD-LARLYGRN 150 +V +L ++ +++ ++ +G+T L + Sbjct: 153 PHIVHYLTENGHKQADLRRQDSRGNTVLHALVAIADNT 190 Score = 43.0 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 32/151 (21%), Positives = 55/151 (36%), Gaps = 34/151 (22%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53 L A R + L++ +V+AQ FG L + P I Sbjct: 97 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIV 156 Query: 54 RRLLLRG---ANPDLKDRTGFAVIH--DAARAGFLDTLQ--------TLLEFQA---DVN 97 L G A+ +D G V+H A + + L++ D N Sbjct: 157 HYLTENGHKQADLRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDTN 216 Query: 98 IE---DNEGNLPLHLAAKEGHLRVVEFLVKH 125 +E +N+G PL +AAK G + + + +++ Sbjct: 217 LEALLNNDGLSPLMMAAKTGKIGIFQHIIRR 247 Score = 34.5 bits (78), Expect = 0.020, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 25/74 (33%), Gaps = 15/74 (20%) Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146 G LH+A + VE LV+ A +V + G+ LA Sbjct: 91 YRGQTALHIAIERRCKHYVELLVEKGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 149 Query: 147 YGRNEVVSLMQANG 160 + +V + NG Sbjct: 150 TNQPHIVHYLTENG 163 Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 29/105 (27%), Gaps = 21/105 (20%) Query: 78 ARAGFLDTLQTLLEF--QADVNIEDNE------GNLPLHLAA---KEGHLRVVEFLVKHT 126 G D L+ LL F + D E G L A G + L+ Sbjct: 13 VSRGSPDGLEGLLSFLLTHKKRLTDEEFREPSTGKTCLPKALLNLSAGRNDTIPILLDIA 72 Query: 127 ASNVGHRNH----------KGDTACDLARLYGRNEVVSLMQANGA 161 R +G TA +A V L+ GA Sbjct: 73 EKTGNMREFINSPFRDVYYRGQTALHIAIERRCKHYVELLVEKGA 117 >6MHW-A nrPDB Length = 826 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 23/103 (22%), Positives = 41/103 (39%), Gaps = 14/103 (13%) Query: 37 FGRTALQVM-KLGNPEIARRLLLR-GANPDLKDRTGFAVIH-DAARAGFLDTLQTLLEFQ 93 FG T L + PEI + L+ + +D G ++H A T ++ Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRM 321 Query: 94 ADV-----------NIEDNEGNLPLHLAAKEGHLRVVEFLVKH 125 D+ +N+G PL LAAK G ++++++ Sbjct: 322 YDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364 Score = 46.5 bits (109), Expect = 5e-06, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 41/101 (40%), Gaps = 12/101 (11%) Query: 69 TGFAVIHDAARAGFLDTLQTLLEF-QADVNIEDNEGNLPLH----LAAK-EGHLRVVE-- 120 G + AA + +Q L+E Q D+ D+ GN LH +A + V+ Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFKTQNDFVKRM 321 Query: 121 ---FLVKHTASNV-GHRNHKGDTACDLARLYGRNEVVSLMQ 157 L++ + RN+ G T LA G+ E++ + Sbjct: 322 YDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYIL 362 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 52/159 (32%), Gaps = 32/159 (20%) Query: 13 AARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLG----NPEIARRLLLRGANPDLKDR 68 R E + L + + + G+T L L EI R LL D+ R Sbjct: 147 CRRRHDEDVPDFLMHKLTAS---DTGKTCLMKALLNINPNTKEIVRILLAFAEENDILGR 203 Query: 69 -----------TGFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EG 103 G ++ A D L+ ADVN G Sbjct: 204 FINAEYTEEAYEGQTALNIAIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFG 263 Query: 104 NLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACD 142 PL LAA +V+ L++H +++ R+ +G+ Sbjct: 264 ETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILH 302 >4DX2-A nrPDB Length = 259 Score = 47.6 bits (112), Expect = 2e-06, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 37/98 (37%), Gaps = 17/98 (17%) Query: 70 GFAVIHDAARAGFLDTLQTLLEFQADVNIEDN--------------EGNLPLHLAAKEGH 115 G +H A ++ L+ ADV+ + G LPL LAA Sbjct: 91 GQTALHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQ 150 Query: 116 LRVVEFLVKHT--ASNVGHRNHKGDTACD-LARLYGRN 150 +V +L ++ +++ ++ +G+T L + Sbjct: 151 PHIVNYLTENPHKKADMRRQDSRGNTVLHALVAIADNT 188 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 29/156 (18%), Positives = 52/156 (33%), Gaps = 36/156 (23%) Query: 9 LASAAARGDLEQLTSLLQNNVNVNAQNG--------------FGRTALQVM-KLGNPEIA 53 L A R + L+ +V+AQ FG L + P I Sbjct: 95 LHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIV 154 Query: 54 RRLLLRG---ANPDLKDRTGFAVIH-DAARAGF----------------LDTLQTLLEFQ 93 L A+ +D G V+H A A L + + Sbjct: 155 NYLTENPHKKADMRRQDSRGNTVLHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDSN 214 Query: 94 ADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASN 129 + + +N+G PL +AAK G + + + +++ ++ Sbjct: 215 LEA-VLNNDGLSPLMMAAKTGKIGIFQHIIRREVTD 249 Score = 33.4 bits (75), Expect = 0.053, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 24/73 (32%), Gaps = 15/73 (20%) Query: 101 NEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNH--------------KGDTACDLARL 146 G LH+A + VE LV A +V + G+ LA Sbjct: 89 YRGQTALHIAIERRCKHYVELLVAQGA-DVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 147 Query: 147 YGRNEVVSLMQAN 159 + +V+ + N Sbjct: 148 TNQPHIVNYLTEN 160 Score = 27.6 bits (60), Expect = 2.8, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 20/72 (27%), Gaps = 13/72 (18%) Query: 103 GNLPLHLAA---KEGHLRVVEFLVKHTASNVGHRNH----------KGDTACDLARLYGR 149 G L A G + L+ R +G TA +A Sbjct: 44 GKTCLPKALLNLSNGRNDTIPVLLDIAERTGNMREFINSPFRDIYYRGQTALHIAIERRC 103 Query: 150 NEVVSLMQANGA 161 V L+ A GA Sbjct: 104 KHYVELLVAQGA 115 >5Z96-A nrPDB Length = 755 Score = 45.7 bits (107), Expect = 9e-06, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 55/144 (38%), Gaps = 24/144 (16%) Query: 3 EPWGNELASAAARGDLEQLTSLLQNN-----VNVNAQNGFGRTALQVMKLGNPEIARRLL 57 P +A +GD + L+ +N+N + GRTAL + LL Sbjct: 30 SPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELL 89 Query: 58 LRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQ-------ADVNIEDNEGN------ 104 L N + G A++H A R + ++ LL + + D + + Sbjct: 90 LS-FNVYV----GDALLH-AIRKEVVGAVELLLNHKKPSGEKQVPPILLDKQFSEFTPDI 143 Query: 105 LPLHLAAKEGHLRVVEFLVKHTAS 128 P+ LAA + +++ LV+ S Sbjct: 144 TPIILAAHTNNYEIIKLLVQKGVS 167 >4CJ9-A nrPDB Length = 794 Score = 30.7 bits (68), Expect = 0.29, Method: Composition-based stats. Identities = 25/162 (15%), Positives = 61/162 (37%), Gaps = 11/162 (6%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMK-LGNPEIARRLLLRGANPDLKDRTG 70 A G + L ++L++ +N + +++ G + + +L A D + + Sbjct: 586 AGNNGGAQALKAVLEHEATLNERGFSRADIVKIAGNGGGAQALKAVLEHEATLDERGFSR 645 Query: 71 FAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNV 130 ++ A G L+ +LE +N + +AA G + ++ +++H + Sbjct: 646 ADIVRIAGNGGGAQALKAVLEHGPTLNERGFNLTDIVEMAANSGGAQALKAVLEHGPTLR 705 Query: 131 GHRNHKGDTACDLA--RLYGRNEVVSLMQANG----AGGATN 166 +G + D+ G + + + G G +N Sbjct: 706 ----QRGLSLIDIVEIASNGGAQALKAVLKYGPVLMQAGRSN 743 >3LJQ-A nrPDB Length = 299 Score = 30.7 bits (68), Expect = 0.36, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 9/100 (9%) Query: 6 GNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDL 65 NE+ +A A G E++ + ++ V N GRT Q K I + + RG +L Sbjct: 198 DNEIGAATATGHGEEVIRTVGTHLVVELMNQ-GRTPQQACKEAVERIVKIVNRRGK--NL 254 Query: 66 KD-RTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104 KD + GF ++ G ++ + + D +GN Sbjct: 255 KDIQVGFIALNKKGEYG-----AYCIQDGFNFAVHDQKGN 289 >4WVX-A nrPDB Length = 326 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 12 AAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLG--NPEIARRLLLRGANP 63 A+++G + + + AQ G + + G PE A LL GA+P Sbjct: 147 ASSKGRITEYEKMFFRAA-ARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADP 199 >2DI3-A nrPDB Length = 239 Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 69 TGFAVIHDAARAGFLDTLQTLLEFQADVNIE 99 G+A +H +A G D + LLE D ++ Sbjct: 106 EGWAALHSSAERGDWDVAEALLEKMDDPSLP 136 >1HXH-A nrPDB Length = 253 Score = 28.0 bits (61), Expect = 2.2, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 28/83 (33%), Gaps = 8/83 (9%) Query: 45 MKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGN 104 E+ + LL GA D A AA G + DV+ E + Sbjct: 15 ASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGERSMFV-----RHDVSSEADWT- 68 Query: 105 LPLHLAAKEGHLRVVEFLVKHTA 127 L +AA + L + LV + Sbjct: 69 --LVMAAVQRRLGTLNVLVNNAG 89 >5Z56-q nrPDB Length = 504 Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 6/63 (9%) Query: 74 IHDAARAG------FLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127 +H A+ G +L AD N+ + + LA +GH + V +V H + Sbjct: 216 LHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 275 Query: 128 SNV 130 ++ Sbjct: 276 QDL 278 >4LG8-A nrPDB Length = 354 Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 6/63 (9%) Query: 74 IHDAARAG------FLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTA 127 +H A+ G +L AD N+ + + LA +GH + V +V H + Sbjct: 66 LHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPS 125 Query: 128 SNV 130 ++ Sbjct: 126 QDL 128 >5XE7-A nrPDB Length = 312 Score = 27.2 bits (59), Expect = 3.7, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 8 ELASAAARGDLEQLTSLLQNNVNVNAQ-NGFGRTALQV-MKLGNPEIARRLL 57 L +A A GDL+ + SLL +V + G+ V G+ ++ R +L Sbjct: 183 RLMAAMAAGDLDTVVSLLHP--DVTFTGDSNGKAPTAVRAVRGSDKVVRFIL 232 >1JI6-A nrPDB Length = 589 Score = 26.5 bits (57), Expect = 5.6, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 26/65 (40%), Gaps = 2/65 (3%) Query: 5 WGNELASAAARGDLEQLTSLLQNNVN-VNAQNGFGRTALQVMKLGNPEIARRLLLRGANP 63 ++ A L +L L N + VNA N + +T L + + + R L + A Sbjct: 55 IDKKIEEYAKSKALAELQGLQNNFEDYVNALNSWKKTPLSLRSKRSQDRIRELFSQ-AES 113 Query: 64 DLKDR 68 ++ Sbjct: 114 HFRNS 118 >1KKT-A nrPDB Length = 511 Score = 26.5 bits (57), Expect = 5.7, Method: Composition-based stats. Identities = 9/52 (17%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 27 NNVNVNAQNGFGRTALQV----MKLGNPEIARRLLLRGANPDLKDRTGFAVI 74 +N + +++NG+G +A+ + +G ++ +L A+ D + + Sbjct: 69 SNGHADSRNGWGASAVDALSTAVIMGKADVVNAILEHVADIDFSKTSDTVSL 120 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.144 0.381 Lambda K H 0.267 0.0444 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,122,898 Number of Sequences: 36641 Number of extensions: 222496 Number of successful extensions: 1755 Number of sequences better than 10.0: 85 Number of HSP's better than 10.0 without gapping: 138 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 577 Number of HSP's gapped (non-prelim): 483 length of query: 168 length of database: 10,336,785 effective HSP length: 90 effective length of query: 78 effective length of database: 7,039,095 effective search space: 549049410 effective search space used: 549049410 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 56 (26.1 bits)