BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P42771 (156 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2A5E-A nrPDB 306 3e-84 1D9S-A nrPDB 209 3e-55 1BD8-A nrPDB 100 3e-22 1BLX-B nrPDB 99 8e-22 1G3N-B nrPDB 85 2e-17 5AQ9-A nrPDB 72 7e-14 5AQA-A nrPDB 68 2e-12 5CBO-A nrPDB 67 3e-12 5AQB-A nrPDB 67 5e-12 5MIO-C nrPDB 64 2e-11 5H76-A nrPDB 61 2e-10 5AQ7-A nrPDB 60 3e-10 5JHQ-A nrPDB 57 3e-09 5ET1-A nrPDB 54 4e-08 4Z68-A nrPDB 51 2e-07 6FES-A nrPDB 51 2e-07 6MWQ-A nrPDB 49 1e-06 5HKP-A nrPDB 44 4e-05 6BY9-A nrPDB 42 1e-04 5GP7-A nrPDB 42 1e-04 3T9K-A nrPDB 40 4e-04 3ZKJ-A nrPDB 39 0.001 3B7B-A nrPDB 37 0.004 4O1O-A nrPDB 37 0.005 2DWZ-A nrPDB 36 0.006 3EU9-A nrPDB 35 0.011 4NIK-A nrPDB 35 0.012 2KXP-C nrPDB 35 0.012 3LJN-A nrPDB 32 0.16 3EHQ-A nrPDB 31 0.21 4OT9-A nrPDB 31 0.26 4OAU-C nrPDB 30 0.45 5U0K-A nrPDB 30 0.61 3S6O-A nrPDB 29 0.72 3IHG-A nrPDB 29 0.81 5UQE-A nrPDB 28 1.1 5U0J-A nrPDB 28 1.6 5DND-A nrPDB 28 1.7 3BXY-A nrPDB 27 3.6 5K9T-A nrPDB 27 3.9 6AUN-A nrPDB 27 4.0 4UAD-A nrPDB 26 6.1 6E2G-A nrPDB 26 7.4 2YRI-A nrPDB 26 7.4 >2A5E-A nrPDB Length = 156 Score = 306 bits (783), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 156/156 (100%), Positives = 156/156 (100%) Query: 1 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA 60 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA Sbjct: 1 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA 60 Query: 61 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE Sbjct: 61 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 Query: 121 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD 156 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD Sbjct: 121 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD 156 >1D9S-A nrPDB Length = 136 Score = 209 bits (533), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 107/120 (89%), Positives = 111/120 (92%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADP 75 LATAAARG+VE VR LLEAGA PNA N +GRRPIQVMMMGSA+VAELLLLHGAEPNCADP Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCADP 75 Query: 76 ATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 ATLTRPVHDAAREGFLDTLVVLHRAGARLDV DAWGRLPVDLAEE GHRD+ARYL AA G Sbjct: 76 ATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAATG 135 >1BD8-A nrPDB Length = 156 Score = 100 bits (248), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 61/122 (50%), Positives = 76/122 (62%), Gaps = 2/122 (1%) Query: 12 SADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEP 70 + D L+ AAARG V+EVR LL + P+A N +G+ +QVMM GS +A LL GA P Sbjct: 2 AGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASP 61 Query: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 N D + T PVHDAAR GFLDTL VL GA ++V D G LP+ LA + GH V +L Sbjct: 62 NVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 120 Query: 131 RA 132 A Sbjct: 121 AA 122 >1BLX-B nrPDB Length = 166 Score = 99.0 bits (245), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 61/118 (51%), Positives = 74/118 (62%), Gaps = 2/118 (1%) Query: 14 DWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNC 72 D L+ AAARG V+EVR LL + P+A N +G+ +QVMM GS VA LL GA PN Sbjct: 10 DRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPNV 69 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 D A+ T PVHDAAR GFLDTL VL GA ++ D+ G LP+ LA GH V +L Sbjct: 70 QD-ASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL 126 >1G3N-B nrPDB Length = 168 Score = 84.7 bits (208), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAE 69 EP + LA+AAARG +E++ +LL+ NA N +GR +QVM +G+ +A LLL GA Sbjct: 3 EPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN 62 Query: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129 P+ D +HDAAR GFLDTL L A +++ D G LP+ LA + GH V + Sbjct: 63 PDLKDRTGFA-VIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 Query: 130 LRAAAGGTRGSNHARIDAA 148 L G + + D A Sbjct: 122 LVKHTASNVGHRNHKGDTA 140 >5AQ9-A nrPDB Length = 422 Score = 72.4 bits (176), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 44/120 (36%), Positives = 71/120 (59%), Gaps = 2/120 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + +G P+ + G + E+LL +GA+ N D Sbjct: 51 LHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD 110 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 +T P+H AA+ G+L+ + VL + GA ++ +D +G+ P DLA++ G+ DV L+ AA Sbjct: 111 SDGMT-PLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAA 169 Score = 48.5 bits (114), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Query: 45 GRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARL 104 GR+ ++ G +L+ +GA+ N AD T T P+H AA G L+ + VL + GA + Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADN-TGTTPLHLAAYSGHLEIVEVLLKHGADV 73 Query: 105 DVRDAWGRLPVDLAEELGHRDVARYL 130 D D +G P+ LA GH ++ L Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVL 99 Score = 27.3 bits (59), Expect = 2.5, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 27/53 (50%) Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 L R + +AAR G D + +L GA ++ D G P+ LA GH ++ L Sbjct: 14 LGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVL 66 >5AQA-A nrPDB Length = 418 Score = 67.8 bits (164), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 44/119 (36%), Positives = 70/119 (58%), Gaps = 2/119 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + +G P+ + G + E+LL +GA+ N D Sbjct: 51 LHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD 110 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 +T P+H AA+ G+ + + VL +AGA +D +D +G+ P+ LA + GH ++A L AA Sbjct: 111 SDGMT-PLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 48.1 bits (113), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Query: 45 GRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARL 104 GR+ ++ G +L+ +GA+ N AD T T P+H AA G L+ + VL + GA + Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADN-TGTTPLHLAAYSGHLEIVEVLLKHGADV 73 Query: 105 DVRDAWGRLPVDLAEELGHRDVARYL 130 D D +G P+ LA GH ++ L Sbjct: 74 DASDVFGYTPLHLAAYWGHLEIVEVL 99 Score = 27.3 bits (59), Expect = 2.7, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 27/53 (50%) Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 L R + +AAR G D + +L GA ++ D G P+ LA GH ++ L Sbjct: 14 LGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVL 66 >5CBO-A nrPDB Length = 176 Score = 67.0 bits (162), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 41/116 (35%), Positives = 69/116 (59%), Gaps = 2/116 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G+ +EVR L+ GA NA +++G P+ + G + E+LL +GA+ N +D Sbjct: 7 LLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVNASD 66 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 AT P+H AA+ G+L + VL + GA ++ +D +G+ D++ + G+ D+A L Sbjct: 67 -ATGDTPLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEIL 121 >5AQB-A nrPDB Length = 428 Score = 66.6 bits (161), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 45/116 (38%), Positives = 66/116 (56%), Gaps = 2/116 (1%) Query: 20 AARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCADPATL 78 AA G +E V LL+ GA NA + G P+ + G + E+LL +GA+ N D A Sbjct: 54 AAWGHLEIVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADDQAGF 113 Query: 79 TRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 T P+H AA G L+ + VL + GA ++ +D +G+ P DLA + G+ D+A L AA Sbjct: 114 T-PLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAA 168 >5MIO-C nrPDB Length = 573 Score = 63.9 bits (154), Expect = 2e-11, Method: Composition-based stats. Identities = 42/116 (36%), Positives = 63/116 (54%), Gaps = 2/116 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCAD 74 L AA G+ +EVR L+ GA NA ++ G P+ + G + E+LL HGA+ + +D Sbjct: 414 LLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVSASD 473 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 T P+H AA G L+ + VL + GA ++ D WG P+ LA +GH + L Sbjct: 474 LMGST-PLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEAL 528 Score = 40.4 bits (93), Expect = 3e-04, Method: Composition-based stats. Identities = 24/60 (40%), Positives = 36/60 (60%), Gaps = 1/60 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA NA +++G P+++ +MG ++ E LL HGA+ N D Sbjct: 480 LHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALLKHGADVNAQD 539 Score = 32.0 bits (71), Expect = 0.10, Method: Composition-based stats. Identities = 19/53 (35%), Positives = 28/53 (52%) Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 L + + +AAR G D + VL GA ++ DA G P+ LA GH ++ L Sbjct: 410 LGKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVL 462 Score = 26.6 bits (57), Expect = 5.2, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELL 63 L AA G ++ V ALL+ GA NA + +G+ + GS +AE+L Sbjct: 513 LRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEIL 561 >5H76-A nrPDB Length = 201 Score = 60.8 bits (146), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 39/116 (33%), Positives = 68/116 (58%), Gaps = 3/116 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + +G P+ + G + E+LL +GA+ N D Sbjct: 43 LHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD 102 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 +T P+H AA+ G+L+ + VL + GA ++ +D +G+ D++ + G+ D+A+ L Sbjct: 103 SDGMT-PLHLAAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLAQIL 156 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 1/86 (1%) Query: 45 GRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARL 104 GR+ ++ G +L+ +GA+ N AD T T P+H AA G L+ + VL + GA + Sbjct: 7 GRKLLEAARAGQDDEVRILMANGADVNAADN-TGTTPLHLAAYSGHLEIVEVLLKHGADV 65 Query: 105 DVRDAWGRLPVDLAEELGHRDVARYL 130 D D +G P+ LA GH ++ L Sbjct: 66 DASDVFGYTPLHLAAYWGHLEIVEVL 91 Score = 26.9 bits (58), Expect = 3.5, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 27/53 (50%) Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 L R + +AAR G D + +L GA ++ D G P+ LA GH ++ L Sbjct: 6 LGRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVL 58 >5AQ7-A nrPDB Length = 418 Score = 60.5 bits (145), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 44/119 (36%), Positives = 65/119 (54%), Gaps = 2/119 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G + V LL+ GA NA + G P+ + G + E+LL +GA N D Sbjct: 51 LHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATD 110 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 T P+H AA G+ + + VL +AGA +D +D +G+ P+ LA + GH ++A L AA Sbjct: 111 VIG-TAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 >5JHQ-A nrPDB Length = 482 Score = 57.0 bits (136), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 40/105 (38%), Positives = 58/105 (55%), Gaps = 2/105 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA GR + V LL+ GA +A + G P+ G A V LLL GA+PN D Sbjct: 53 LHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD 112 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE 119 T P+H+AA +G +D +VL + GA ++R+ G+ +DLA+ Sbjct: 113 NWNYT-PLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLAD 156 Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA RV V+ LL+ GA +A + G P+ G V ELLL HGA N D Sbjct: 206 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 265 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H+AA + ++ +L GA + + G+ VD+A Sbjct: 266 LWQFT-PLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 308 Score = 41.6 bits (96), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM---MGSARVAELLLLH 66 E D L AA G E++ ALL + N S GR+ + + R+ +LLL H Sbjct: 166 EYKKDELLEAARSGNEEKLMALLTPLNV-NCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 224 Query: 67 GAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPV 115 GA+ + D L P+H+A G + +L + GA ++ D W P+ Sbjct: 225 GADVHAKDKGGLV-PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPL 272 Score = 40.8 bits (94), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 58 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 +V ELLL GA N + +T P+H AA D + VLH+ GA+++ D G+ + Sbjct: 372 QVTELLLRKGANVNEKNKDFMT-PLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHR 430 Query: 118 AEELGHRDVARYL 130 A GH R L Sbjct: 431 AALAGHLQTCRLL 443 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 59/136 (43%), Gaps = 21/136 (15%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-------QVMMMGSARVAELL----- 63 L AA +G+++ LL+ GA PN N+ G+ + + ++ G + ELL Sbjct: 119 LHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARS 178 Query: 64 --------LLHGAEPNC-ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP 114 LL NC A + P+H AA + + +L + GA + +D G +P Sbjct: 179 GNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVP 238 Query: 115 VDLAEELGHRDVARYL 130 + A GH +V L Sbjct: 239 LHNACSYGHYEVTELL 254 Score = 35.8 bits (81), Expect = 0.008, Method: Compositional matrix adjust. Identities = 37/118 (31%), Positives = 52/118 (44%), Gaps = 5/118 (4%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRR--PIQVMM-MGSARVAELLLLHGAEPNC 72 L A G V V+ L++A + NA + GR+ P+ G V E LL GA + Sbjct: 19 LLEACRNGDVSRVKRLVDAANV-NAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHA 77 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 D L P+H+A G + + +L GA + RD W P+ A G DV L Sbjct: 78 RDDGGLI-PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVL 134 >5ET1-A nrPDB Length = 353 Score = 53.5 bits (127), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 35/77 (45%), Positives = 41/77 (53%), Gaps = 2/77 (2%) Query: 55 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP 114 G +V LLLHGAE + P+HDAA G L+ +L GA LDVRD G Sbjct: 252 GHTKVLSWLLLHGAE--ISQDLWGGTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTA 309 Query: 115 VDLAEELGHRDVARYLR 131 DLAE GH +RYLR Sbjct: 310 ADLAEFNGHTHCSRYLR 326 Score = 40.4 bits (93), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 40/124 (32%), Positives = 57/124 (45%), Gaps = 11/124 (8%) Query: 19 AAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPAT 77 AA RG ++ +R+L AG L P+ +S P+ +AR +L L A PA Sbjct: 10 AARRGDLDVLRSLHAAGLLGPSLRDSLDALPVH----HAARSGKLHCLRYLVEEVALPAV 65 Query: 78 L-----TRPVHDAAREGFLDTLV-VLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 P HDAA G+L L +L + G R+ +D G + LA GH DV ++L Sbjct: 66 SRARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLL 125 Query: 132 AAAG 135 G Sbjct: 126 YQGG 129 Score = 28.9 bits (63), Expect = 1.0, Method: Compositional matrix adjust. Identities = 33/117 (28%), Positives = 49/117 (41%), Gaps = 7/117 (5%) Query: 19 AAARGRVEEVRALLEAGA--LPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPA 76 AAA G + ++ LL G + NS G V + LL G + Sbjct: 78 AAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAITTD 137 Query: 77 TLTRPVHDAAREGFLDTLVVL---HRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 T P+H AA +G L +L +L + G + G P+ LA + GH +V +YL Sbjct: 138 TGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNN--GATPLYLACQEGHLEVTKYL 192 >4Z68-A nrPDB Length = 155 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 3/117 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA RV V LL+ GA +A + G P+ G VAELL+ HGA N AD Sbjct: 41 LHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD 100 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 T P+H+AA +G + +L + GA ++ G P+DL ++ G D+ LR Sbjct: 101 LWKFT-PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLR 155 Score = 42.7 bits (99), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 34/118 (28%), Positives = 53/118 (44%), Gaps = 5/118 (4%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM---MGSARVAELLLLHGAEPNC 72 L AA G VE V+ L ++ N + GR+ + V E LL HGA+ + Sbjct: 7 LLEAAKAGDVETVKKLCTVQSV-NCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHA 65 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 D L P+H+A G + +L + GA ++V D W P+ A G ++ + L Sbjct: 66 KDKGGLV-PLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLL 122 >6FES-A nrPDB Length = 367 Score = 50.8 bits (120), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 2/117 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM-MMGSARVAELLLLHGAEPNCAD 74 L AA G + V LL+ GA NA + G P+ + G + E+LL +GA N D Sbjct: 43 LHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATD 102 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 T P+H AA G + + VL + GA +D +G+ P DLA + G+ VAR R Sbjct: 103 VIG-TAPLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARLAR 158 >6MWQ-A nrPDB Length = 493 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Query: 45 GRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARL 104 G++ ++ G +L+ +GA+ N D LT P+H AA+ G L+ + VL + GA + Sbjct: 6 GKKLLEAARAGQDDEVRILMANGADVNALDRFGLT-PLHLAAQRGHLEIVEVLLKCGADV 64 Query: 105 DVRDAWGRLPVDLAEELGHRDVARYL 130 + D WG+ P+ LA GH ++ L Sbjct: 65 NAADLWGQTPLHLAATAGHLEIVEVL 90 Score = 29.6 bits (65), Expect = 0.63, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 29/53 (54%) Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 L + + +AAR G D + +L GA ++ D +G P+ LA + GH ++ L Sbjct: 5 LGKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVL 57 >5HKP-A nrPDB Length = 351 Score = 43.5 bits (101), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA RV V+ LL+ GA +A + G P+ G V ELLL HGA N D Sbjct: 62 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 121 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H+AA + ++ +L GA + + G+ VD+A Sbjct: 122 LWQFT-PLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 164 Score = 42.7 bits (99), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 1/73 (1%) Query: 58 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 +VAELLL GA N + +T P+H AA D + VLH+ GA+++ D+ G+ + Sbjct: 228 QVAELLLRKGANVNEKNKDFMT-PLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHR 286 Query: 118 AEELGHRDVARYL 130 A GH R L Sbjct: 287 AALAGHLQTCRLL 299 Score = 41.6 bits (96), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 5/109 (4%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM---MGSARVAELLLLH 66 E D L AA G E++ ALL + N S GR+ + + R+ +LLL H Sbjct: 22 EYKKDELLEAARSGNEEKLMALLTPLNV-NCHASDGRKSTPLHLAAGYNRVRIVQLLLQH 80 Query: 67 GAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPV 115 GA+ + D L P+H+A G + +L + GA ++ D W P+ Sbjct: 81 GADVHAKDKGGLV-PLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPL 128 >6BY9-A nrPDB Length = 328 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 4/118 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSY--GRRPIQVMM-MGSARVAELLLLHGAEPNC 72 L +A +G +++V +L G PN + R P+ G + +L+ GA + Sbjct: 71 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 130 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 T P+ +AA L+ + L +AGA +D +DA G + LA + GH +V +YL Sbjct: 131 CSEDQRT-PLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 187 >5GP7-A nrPDB Length = 169 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 5/120 (4%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM---MGSARVAELLLLHGAEPNC 72 L AA +G + V+ L + N ++ GR + + + VAE LL HGA+ N Sbjct: 13 LLDAAKKGCLARVQKLCTPENI-NCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 71 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 D L P+H+AA G +D +L + ++ D W P+ A + G + L A Sbjct: 72 QDKGGLI-PLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLA 130 Score = 40.4 bits (93), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA +E LLE GA NA + G P+ G +A LL+ + N D Sbjct: 47 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 106 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H+AA++G +L GA +++ G+ P+DLA Sbjct: 107 KWAFT-PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149 >3T9K-A nrPDB Length = 390 Score = 40.0 bits (92), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 49 IQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRD 108 IQ S E LL +GA N AD A P+H A G + + GA L RD Sbjct: 240 IQATAANSLLACEFLLQNGANVNQADSAG-RGPLHHATILGHTGLACLFLKRGADLGARD 298 Query: 109 AWGRLPVDLAEELGHRDVARYLRAA 133 + GR P+ +A E + D+ LR A Sbjct: 299 SEGRDPLTIAMETANADIVTLLRLA 323 >3ZKJ-A nrPDB Length = 261 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 6/128 (4%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAELLLLHGAEPNCAD 74 L A G + V+ LL+ GA N + P+ + GS LLL HGA Sbjct: 40 LHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGAS---VQ 96 Query: 75 PAT-LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHR-DVARYLRA 132 P + L P+H+AAR G ++ + L G +D + + P+ LA E R V + L + Sbjct: 97 PESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLES 156 Query: 133 AAGGTRGS 140 A +G Sbjct: 157 GADVNQGK 164 Score = 32.7 bits (73), Expect = 0.060, Method: Compositional matrix adjust. Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 6/117 (5%) Query: 6 GSSMEPSADW---LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSAR-VAE 61 G+S++P +D + AA RG VE V +L+ G + S+ P+ + R + Sbjct: 92 GASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVK 151 Query: 62 LLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 LL GA+ N P+H AR + +L GA ++A G+ PV+L Sbjct: 152 KLLESGADVN--QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELV 206 >3B7B-A nrPDB Length = 237 Score = 36.6 bits (83), Expect = 0.004, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 39/76 (51%), Gaps = 1/76 (1%) Query: 55 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP 114 G + +L+ GA + T P+ +AA L+ + L +AGA +D +DA G Sbjct: 22 GHVDICHMLVQAGANIDTCSEDQRT-PLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTC 80 Query: 115 VDLAEELGHRDVARYL 130 + LA + GH +V +YL Sbjct: 81 LHLAAKKGHYEVVQYL 96 Score = 31.6 bits (70), Expect = 0.15, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 27/53 (50%) Query: 81 PVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 P+H AA G +D +L +AGA +D R P+ A E H + +YL A Sbjct: 14 PLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKA 66 >4O1O-A nrPDB Length = 717 Score = 36.6 bits (83), Expect = 0.005, Method: Composition-based stats. Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 8 SMEPSA--DWLATAAARGRVEEVRALLEAGALPN-APNSYGRRPIQ-VMMMGSARVAELL 63 +M+P++ + L A +E+VR LLE GA N +G P+ + M S + LL Sbjct: 2 AMDPASLEEMLTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALL 61 Query: 64 LLHGAEP 70 L HGA+P Sbjct: 62 LKHGADP 68 Score = 29.6 bits (65), Expect = 0.63, Method: Composition-based stats. Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 6/124 (4%) Query: 13 ADWLATAAARGRVEEVRALLEA-GALPNAPNSYGRRPIQVMMM----GSAR-VAELLLLH 66 A L AA +G V V LL A A +A ++ GR + ++ G A+ + LLL H Sbjct: 152 ATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDH 211 Query: 67 GAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDV 126 GA+ N + T + R+ ++L + ++ D G+ + LA EL ++ Sbjct: 212 GADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELRLEEI 271 Query: 127 ARYL 130 A+ L Sbjct: 272 AKLL 275 >2DWZ-A nrPDB Length = 231 Score = 36.2 bits (82), Expect = 0.006, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 2/105 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA++ R E LLE GA P+A + Y + G+ ++ +LL + A N D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQD 169 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE 119 T P+H A E ++ L GA + + + + P+ +A+ Sbjct: 170 TEGNT-PLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAK 213 >3EU9-A nrPDB Length = 240 Score = 35.4 bits (80), Expect = 0.011, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 54/128 (42%), Gaps = 2/128 (1%) Query: 7 SSMEPSADW-LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGS-ARVAELLL 64 + ++ + W + A G E R L+EAG P+ + + + + + + Sbjct: 3 THIDDYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYI 62 Query: 65 LHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHR 124 GA + + P+H A R+G L +V L + GA + D G + LA + GH Sbjct: 63 SKGAIVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHT 122 Query: 125 DVARYLRA 132 + YL A Sbjct: 123 SIVAYLIA 130 Score = 27.3 bits (59), Expect = 2.6, Method: Compositional matrix adjust. Identities = 26/104 (25%), Positives = 40/104 (38%), Gaps = 2/104 (1%) Query: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARV--AELLLLHGAEPNCADPA 76 AA G V L+ G + + G P+ + V LLL N D Sbjct: 116 AAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKY 175 Query: 77 TLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 +H A G + +L AGA +D ++ G +DLA++ Sbjct: 176 HKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQ 219 >4NIK-A nrPDB Length = 230 Score = 35.0 bits (79), Expect = 0.012, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 2/105 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA++ R E LLE GA P+A + Y + G+ ++ +LL + A N D Sbjct: 114 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 173 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE 119 T P+H A E ++ +L GA + + + + P+ +A+ Sbjct: 174 TEGNT-PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 217 >2KXP-C nrPDB Length = 118 Score = 35.0 bits (79), Expect = 0.012, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 2/90 (2%) Query: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPNCADPAT 77 A G ++EV+ + G N GR+P+ G + E LLL GA+ N D Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68 Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVR 107 +T P+ A EG + + +L GA V+ Sbjct: 69 IT-PLLSAVYEGHVSCVKLLLSKGADKTVK 97 >3LJN-A nrPDB Length = 364 Score = 31.6 bits (70), Expect = 0.16, Method: Compositional matrix adjust. Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 26/120 (21%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQV-MMMGSARVAELL--------LLH 66 + AA +G+ +EVR L+E G P N +G + + G A+ L L H Sbjct: 24 IHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEVHSLWH 83 Query: 67 GAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDV 126 G +P+H A D +V L GA+ G++P L E R+V Sbjct: 84 G-----------QKPIHLAVMANKTDLVVAL-VEGAK-----ERGQMPESLLNECDEREV 126 >3EHQ-A nrPDB Length = 222 Score = 31.2 bits (69), Expect = 0.21, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 3/105 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSAR-VAELLLLH-GAEPNCA 73 L AA RG + +R L+ N + G + G + + E+L E N Sbjct: 77 LHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPNIELNQQ 136 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 + T +H AA +G+ D + +L GAR D+R+ +L D+A Sbjct: 137 NKLGDT-ALHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMA 180 >4OT9-A nrPDB Length = 359 Score = 30.8 bits (68), Expect = 0.26, Method: Compositional matrix adjust. Identities = 41/139 (29%), Positives = 59/139 (42%), Gaps = 11/139 (7%) Query: 12 SADWLATAAARGRVEEVRALLEAGA-----LPNAPNSYGRRPIQVMMMG-SARVAELLLL 65 SA LA A G E +RALL++GA L + P+ G P+ + + S +LL+ Sbjct: 156 SAMHLALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVD 215 Query: 66 HGAEPNCADPATLTRPVHDAARE---GFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELG 122 GAE + +H A G + LV RA ++ R G P+ LA LG Sbjct: 216 SGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRAN--VNARTFAGNTPLHLAAGLG 273 Query: 123 HRDVARYLRAAAGGTRGSN 141 + + R L A N Sbjct: 274 YPTLTRLLLKAGADIHAEN 292 >4OAU-C nrPDB Length = 699 Score = 30.0 bits (66), Expect = 0.45, Method: Composition-based stats. Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 13/103 (12%) Query: 16 LATAAARGRVEEVRALLEAGALPN-APNSYGRRPIQ-VMMMGSARVAELLLLHGAEP--- 70 L A V+ V+ LLE GA N G P+ + M + ELLL HGA+P Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68 Query: 71 --NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWG 111 N A P L AA G + L + GA ++ D +G Sbjct: 69 KKNGATPFIL------AAIAGSVKLLKLFLSKGADVNECDFYG 105 >5U0K-A nrPDB Length = 141 Score = 29.6 bits (65), Expect = 0.61, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 3/52 (5%) Query: 82 VHDAAREGFLDTLVVLHRAGARLD--VRDAWGRLPVDLAEELGHRDVARYLR 131 +H AA EG ++ + L A +++ +D WG +P+D A + H +V + L+ Sbjct: 62 LHVAAAEGHIEVVKFLIEA-CKVNPFAKDRWGNIPLDDAVQFNHLEVVKLLQ 112 >3S6O-A nrPDB Length = 321 Score = 29.3 bits (64), Expect = 0.72, Method: Compositional matrix adjust. Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 14/64 (21%) Query: 38 PNAPNS---YGRRPIQVMMMGSARVAELLLLHGAE--PNCADPATLTRPVH-DAAREGFL 91 PN P YGR P+Q G ARVA +L+ E NC +H D A E FL Sbjct: 9 PNYPRDLIGYGRHPVQANWPGRARVAVQFVLNYEEGGENCV--------LHGDPASEQFL 60 Query: 92 DTLV 95 +V Sbjct: 61 SEIV 64 >3IHG-A nrPDB Length = 535 Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 25/49 (51%) Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELG 122 DPA + P+ + R GF V++ R G RL D +G LA ELG Sbjct: 408 DPARVENPLTPSGRPGFRGPHVLVSRHGERLSTVDLFGDGWTLLAGELG 456 >5UQE-A nrPDB Length = 520 Score = 28.5 bits (62), Expect = 1.1, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 3/52 (5%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDV--RDAWGRLPVDLAEELGHRDVARYLR 131 +H AA EG ++ + L A +++ +D W P+D A GH DV + L+ Sbjct: 454 LHVAAAEGHVEVVKFLLEA-CKVNPFPKDRWNNTPMDEALHFGHHDVFKILQ 504 >5U0J-A nrPDB Length = 140 Score = 28.1 bits (61), Expect = 1.6, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 1/51 (1%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDV-RDAWGRLPVDLAEELGHRDVARYLR 131 +H AA EG ++ + L A +D W P+D A GH DV + L+ Sbjct: 61 LHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQ 111 >5DND-A nrPDB Length = 588 Score = 28.1 bits (61), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/52 (36%), Positives = 27/52 (51%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 +H AAR G + +L G ++ RD G P+ LA + HR+ R LR A Sbjct: 459 LHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKA 510 >3BXY-A nrPDB Length = 285 Score = 26.9 bits (58), Expect = 3.6, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 7/81 (8%) Query: 17 ATAAARGRVEEVRALLEAGALPNAPNSYGR----RPIQVMMMGSARVAELLLLHGAEPNC 72 A R V +V ALL++GAL A G+ + ++ ++ S R+ + ++ GAE Sbjct: 34 ADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRY 93 Query: 73 ADPATLTRPVHDAAR---EGF 90 D + +D AR EGF Sbjct: 94 FDKVPMKFADYDEARFQKEGF 114 >5K9T-A nrPDB Length = 578 Score = 26.9 bits (58), Expect = 3.9, Method: Compositional matrix adjust. Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 16/86 (18%) Query: 7 SSMEPSADWLATAAARGRVEEVRALLEAGA-----LPNA--------PNSYGRRPIQVMM 53 ++MEP + L+ +G+ E RA L AGA +P A +G R V + Sbjct: 17 NAMEPEMEKLSDEELKGKTAEFRARLAAGAVLENLIPEAFAVVREASKRVFGMRHFDVQL 76 Query: 54 MGSARVAELLLLHGAEPNCADPATLT 79 +G + E + AE + TLT Sbjct: 77 LGGMVLNERCI---AEMRTGEGKTLT 99 >6AUN-A nrPDB Length = 752 Score = 26.9 bits (58), Expect = 4.0, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 6/88 (6%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADP 75 L A ++ +E ++AL+ GA + PN +G P + S ++ +L+ + A P Sbjct: 354 LHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMASKISKQLQDLMPISRAR----KP 409 Query: 76 ATLTRPVHDAAREGFLDTLVVLHRAGAR 103 A + + D R D L+ L G + Sbjct: 410 AFILSSMRDEKR--IHDHLLCLDGGGVK 435 >4UAD-A nrPDB Length = 479 Score = 26.2 bits (56), Expect = 6.1, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 19/31 (61%) Query: 8 SMEPSADWLATAAARGRVEEVRALLEAGALP 38 +++ A W T A G ++ + ++EAGA+P Sbjct: 83 TLQFEAAWALTNIASGTSQQTKIVIEAGAVP 113 >6E2G-A nrPDB Length = 727 Score = 25.8 bits (55), Expect = 7.4, Method: Composition-based stats. Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 14/73 (19%) Query: 16 LATAAARGRVEEVRALLEAGALPNA----------PNS---YGRRPIQ-VMMMGSARVAE 61 L A V VRALL GA +A P++ YG P+ +GS + Sbjct: 121 LHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVR 180 Query: 62 LLLLHGAEPNCAD 74 LL+ HGA+ D Sbjct: 181 LLIEHGADIRAQD 193 >2YRI-A nrPDB Length = 353 Score = 25.8 bits (55), Expect = 7.4, Method: Compositional matrix adjust. Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 2/31 (6%) Query: 46 RRPIQVMMMG--SARVAELLLLHGAEPNCAD 74 R P+ V++ G S RVAE+ LHG +P D Sbjct: 74 RGPVLVLVNGAFSQRVAEMAALHGLDPEVLD 104 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2A5E-A nrPDB 200 3e-52 5AQ9-A nrPDB 169 6e-43 5AQA-A nrPDB 162 4e-41 6FES-A nrPDB 161 1e-40 5MIO-C nrPDB 160 3e-40 5AQ7-A nrPDB 157 2e-39 5AQB-A nrPDB 156 4e-39 6MWQ-A nrPDB 150 2e-37 5CBO-A nrPDB 148 9e-37 5H76-A nrPDB 145 6e-36 1D9S-A nrPDB 144 2e-35 1G3N-B nrPDB 142 5e-35 4Z68-A nrPDB 136 4e-33 1BLX-B nrPDB 131 1e-31 3ZKJ-A nrPDB 130 3e-31 1BD8-A nrPDB 130 3e-31 5JHQ-A nrPDB 126 4e-30 5HKP-A nrPDB 124 2e-29 6BY9-A nrPDB 121 2e-28 5GP7-A nrPDB 120 3e-28 3T9K-A nrPDB 100 4e-22 5ET1-A nrPDB 97 2e-21 Sequences not found previously or not previously below threshold: 4NIK-A nrPDB 97 3e-21 3B7B-A nrPDB 97 4e-21 2DWZ-A nrPDB 96 5e-21 3EU9-A nrPDB 85 8e-18 4OAU-C nrPDB 80 3e-16 5DND-A nrPDB 78 1e-15 6AUN-A nrPDB 78 2e-15 4O1O-A nrPDB 77 4e-15 3EHQ-A nrPDB 75 1e-14 5D68-A nrPDB 74 3e-14 2KXP-C nrPDB 73 5e-14 1WG0-A nrPDB 71 2e-13 3UI2-A nrPDB 69 7e-13 3DEO-A nrPDB 69 8e-13 4OT9-A nrPDB 67 3e-12 6EMK-G nrPDB 63 4e-11 6CV9-A nrPDB 61 3e-10 6DMR-A nrPDB 60 3e-10 6E2G-A nrPDB 59 9e-10 5U0K-A nrPDB 58 1e-09 3LVQ-E nrPDB 57 3e-09 3LJN-A nrPDB 57 5e-09 2B0O-E nrPDB 55 1e-08 2RFA-A nrPDB 55 1e-08 5UQE-A nrPDB 54 2e-08 6CUD-A nrPDB 54 3e-08 6OO7-A nrPDB 54 3e-08 6DJS-A nrPDB 53 5e-08 6BOA-A nrPDB 53 5e-08 5U0J-A nrPDB 52 9e-08 4BSZ-B nrPDB 52 1e-07 5AN8-A nrPDB 52 1e-07 1DCQ-A nrPDB 50 3e-07 2F37-A nrPDB 48 2e-06 6BO5-A nrPDB 47 3e-06 5HI9-A nrPDB 47 3e-06 5UIL-A nrPDB 46 8e-06 2ETB-A nrPDB 45 1e-05 4XD0-A nrPDB 45 2e-05 4N5Q-A nrPDB 44 2e-05 6DVZ-A nrPDB 43 6e-05 5IRX-A nrPDB 40 5e-04 2NYJ-A nrPDB 39 0.001 6C8G-A nrPDB 39 0.001 6BBJ-A nrPDB 39 0.001 6MHW-A nrPDB 38 0.001 3W9G-A nrPDB 38 0.001 4DX2-A nrPDB 35 0.020 6ED3-A nrPDB 30 0.32 6G1K-A nrPDB 29 0.72 6EC3-A nrPDB 28 2.4 2H12-A nrPDB 26 6.1 5XE7-A nrPDB 26 6.2 3NA5-A nrPDB 26 7.6 3B8B-A nrPDB 26 9.3 >2A5E-A nrPDB Length = 156 Score = 200 bits (508), Expect = 3e-52, Method: Composition-based stats. Identities = 156/156 (100%), Positives = 156/156 (100%) Query: 1 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA 60 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA Sbjct: 1 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVA 60 Query: 61 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE Sbjct: 61 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 Query: 121 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD 156 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD Sbjct: 121 LGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD 156 >5AQ9-A nrPDB Length = 422 Score = 169 bits (427), Expect = 6e-43, Method: Composition-based stats. Identities = 44/124 (35%), Positives = 71/124 (57%), Gaps = 2/124 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + +G P+ G + E+LL +GA+ N D Sbjct: 51 LHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD 110 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 +T P+H AA+ G+L+ + VL + GA ++ +D +G+ P DLA++ G+ DV L+ AA Sbjct: 111 SDGMT-PLHLAAKWGYLEIVEVLLKHGADVNAQDKFGKTPFDLADDNGNDDVGTLLQVAA 169 Query: 135 GGTR 138 + Sbjct: 170 AADQ 173 Score = 150 bits (380), Expect = 2e-37, Method: Composition-based stats. Identities = 44/145 (30%), Positives = 72/145 (49%), Gaps = 6/145 (4%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPN 71 L AA G+ +EVR L+ GA NA ++ G P+ + G + E+LL HGA+ + Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 +D T P+H AA G L+ + VL + GA ++ D+ G P+ LA + G+ ++ L Sbjct: 75 ASDVFGYT-PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYLEIVEVLL 133 Query: 132 AAAGGTRGSNHARIDAAEGPSDIPD 156 +A+ + P D+ D Sbjct: 134 KHGADV----NAQDKFGKTPFDLAD 154 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Query: 43 SYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 GR+ ++ G +L+ +GA+ N AD T P+H AA G L+ + VL + GA Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTG-TTPLHLAAYSGHLEIVEVLLKHGA 71 Query: 103 RLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 +D D +G P+ LA GH ++ L Sbjct: 72 DVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA 104 >5AQA-A nrPDB Length = 418 Score = 162 bits (411), Expect = 4e-41, Method: Composition-based stats. Identities = 44/119 (36%), Positives = 69/119 (57%), Gaps = 2/119 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + +G P+ G + E+LL +GA+ N D Sbjct: 51 LHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD 110 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 +T P+H AA+ G+ + + VL +AGA +D +D +G+ P+ LA + GH ++A L AA Sbjct: 111 SDGMT-PLHLAAKWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 150 bits (378), Expect = 3e-37, Method: Composition-based stats. Identities = 41/124 (33%), Positives = 66/124 (53%), Gaps = 2/124 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPN 71 L AA G+ +EVR L+ GA NA ++ G P+ + G + E+LL HGA+ + Sbjct: 15 GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLLKHGADVD 74 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 +D T P+H AA G L+ + VL + GA ++ D+ G P+ LA + G++++ L Sbjct: 75 ASDVFGYT-PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYKEIVEVLL 133 Query: 132 AAAG 135 A Sbjct: 134 KAGA 137 Score = 104 bits (260), Expect = 1e-23, Method: Composition-based stats. Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 1/93 (1%) Query: 43 SYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 GR+ ++ G +L+ +GA+ N AD T P+H AA G L+ + VL + GA Sbjct: 13 DLGRKLLEAARAGQDDEVRILMANGADVNAADNTG-TTPLHLAAYSGHLEIVEVLLKHGA 71 Query: 103 RLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 +D D +G P+ LA GH ++ L Sbjct: 72 DVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGA 104 >6FES-A nrPDB Length = 367 Score = 161 bits (408), Expect = 1e-40, Method: Composition-based stats. Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 2/118 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCAD 74 L AA G + V LL+ GA NA + G P+ + G + E+LL +GA N D Sbjct: 43 LHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATD 102 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 T P+H AA G + + VL + GA +D +G+ P DLA + G+ VAR R Sbjct: 103 VIG-TAPLHLAAMWGHEEIVEVLLKNGADARAQDKFGKTPEDLARDNGYESVARLARK 159 Score = 145 bits (367), Expect = 5e-36, Method: Composition-based stats. Identities = 42/130 (32%), Positives = 61/130 (46%), Gaps = 2/130 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPN 71 L AA G+ +EVR LL GA N + G P+ + G + E+LL +GA+ N Sbjct: 7 GKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 66 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 D T P+H AA G L+ + VL + GA ++ D G P+ LA GH ++ L Sbjct: 67 ANDERGHT-PLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHEEIVEVLL 125 Query: 132 AAAGGTRGSN 141 R + Sbjct: 126 KNGADARAQD 135 >5MIO-C nrPDB Length = 573 Score = 160 bits (404), Expect = 3e-40, Method: Composition-based stats. Identities = 42/124 (33%), Positives = 63/124 (50%), Gaps = 2/124 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPN 71 L AA G+ +EVR L+ GA NA ++ G P+ + G + E+LL HGA+ + Sbjct: 411 GKKLLEAARAGQDDEVRVLMANGADVNATDASGLTPLHLAATYGHLEIVEVLLKHGADVS 470 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 +D T P+H AA G L+ + VL + GA ++ D WG P+ LA +GH + L Sbjct: 471 ASDLMGST-PLHLAALIGHLEIVEVLLKHGADVNAVDTWGDTPLRLAAVMGHLKIVEALL 529 Query: 132 AAAG 135 Sbjct: 530 KHGA 533 Score = 147 bits (372), Expect = 1e-36, Method: Composition-based stats. Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 2/118 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + G P+ + + G + E+LL HGA+ N D Sbjct: 447 LHLAATYGHLEIVEVLLKHGADVSASDLMGSTPLHLAALIGHLEIVEVLLKHGADVNAVD 506 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 T P+ AA G L + L + GA ++ +D +G+ D + + G D+A L+ Sbjct: 507 TWGDT-PLRLAAVMGHLKIVEALLKHGADVNAQDKFGKTAYDTSIDNGSEDLAEILQK 563 >5AQ7-A nrPDB Length = 418 Score = 157 bits (397), Expect = 2e-39, Method: Composition-based stats. Identities = 44/119 (36%), Positives = 65/119 (54%), Gaps = 2/119 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCAD 74 L AA G + V LL+ GA NA + G P+ + G + E+LL +GA N D Sbjct: 51 LHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAGVNATD 110 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 T P+H AA G+ + + VL +AGA +D +D +G+ P+ LA + GH ++A L AA Sbjct: 111 VIG-TAPLHLAAMWGYKEIVEVLLKAGADVDAQDKFGKRPLWLAADQGHAEIAAKLVAA 168 Score = 135 bits (340), Expect = 7e-33, Method: Composition-based stats. Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 2/124 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPN 71 L AA G+ +EVR LL GA N + G P+ + G + E+LL +GA+ N Sbjct: 15 GKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLHLAAWEGHLGIVEVLLKNGADVN 74 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 D T P+H AA G L+ + VL + GA ++ D G P+ LA G++++ L Sbjct: 75 ANDERGHT-PLHLAAYTGHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGYKEIVEVLL 133 Query: 132 AAAG 135 A Sbjct: 134 KAGA 137 Score = 102 bits (253), Expect = 1e-22, Method: Composition-based stats. Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 1/94 (1%) Query: 43 SYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 G++ ++ G +LL +GA+ N AD T P+H AA EG L + VL + GA Sbjct: 13 DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFT-PLHLAAWEGHLGIVEVLLKNGA 71 Query: 103 RLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136 ++ D G P+ LA GH ++ L G Sbjct: 72 DVNANDERGHTPLHLAAYTGHLEIVEVLLKNGAG 105 >5AQB-A nrPDB Length = 428 Score = 156 bits (394), Expect = 4e-39, Method: Composition-based stats. Identities = 46/120 (38%), Positives = 67/120 (55%), Gaps = 3/120 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA NA + G P+ + G + E+LL +GA+ N D Sbjct: 51 LHLAAW-GHLEIVECLLKNGADVNAADIDGYTPLHLAAFSGHLEIVEVLLKYGADVNADD 109 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 A T P+H AA G L+ + VL + GA ++ +D +G+ P DLA + G+ D+A L AA Sbjct: 110 QAGFT-PLHLAAIFGHLEIVEVLLKNGADVNAQDKFGKTPRDLAIDNGNEDIAEVLGKAA 168 Score = 149 bits (377), Expect = 4e-37, Method: Composition-based stats. Identities = 41/123 (33%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNC 72 L AA G+ +E R L+ GA NA + G P+ + G + E LL +GA+ N Sbjct: 15 GKKLLEAARAGQDDECRILMANGADVNALDEVGWTPLHLAAWGHLEIVECLLKNGADVNA 74 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 AD T P+H AA G L+ + VL + GA ++ D G P+ LA GH ++ L Sbjct: 75 ADIDGYT-PLHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLK 133 Query: 133 AAG 135 Sbjct: 134 NGA 136 Score = 97.0 bits (240), Expect = 3e-21, Method: Composition-based stats. Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 2/95 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA NA + G P+ + G + E+LL +GA+ N D Sbjct: 83 LHLAAFSGHLEIVEVLLKYGADVNADDQAGFTPLHLAAIFGHLEIVEVLLKNGADVNAQD 142 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDA 109 T P A G D VL +A + V+DA Sbjct: 143 KFGKT-PRDLAIDNGNEDIAEVLGKAATLVKVKDA 176 >6MWQ-A nrPDB Length = 493 Score = 150 bits (380), Expect = 2e-37, Method: Composition-based stats. Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 2/124 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPN 71 L AA G+ +EVR L+ GA NA + +G P+ + G + E+LL GA+ N Sbjct: 6 GKKLLEAARAGQDDEVRILMANGADVNALDRFGLTPLHLAAQRGHLEIVEVLLKCGADVN 65 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 AD T P+H AA G L+ + VL + GA ++ D G+ P+ L GH ++ L Sbjct: 66 AADLWGQT-PLHLAATAGHLEIVEVLLKYGADVNALDLIGKTPLHLTAIDGHLEIVEVLL 124 Query: 132 AAAG 135 Sbjct: 125 KHGA 128 Score = 149 bits (377), Expect = 3e-37, Method: Composition-based stats. Identities = 40/127 (31%), Positives = 67/127 (52%), Gaps = 2/127 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPNCAD 74 L AA RG +E V LL+ GA NA + +G+ P+ + G + E+LL +GA+ N D Sbjct: 42 LHLAAQRGHLEIVEVLLKCGADVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVNALD 101 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 T P+H A +G L+ + VL + GA ++ +D +G+ D++ + G+ D+A L+ Sbjct: 102 LIGKT-PLHLTAIDGHLEIVEVLLKHGADVNAQDKFGKTAFDISIDNGNEDLAEILQKLN 160 Query: 135 GGTRGSN 141 Sbjct: 161 LSDIAHR 167 Score = 110 bits (276), Expect = 2e-25, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Query: 43 SYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 G++ ++ G +L+ +GA+ N D LT P+H AA+ G L+ + VL + GA Sbjct: 4 DLGKKLLEAARAGQDDEVRILMANGADVNALDRFGLT-PLHLAAQRGHLEIVEVLLKCGA 62 Query: 103 RLDVRDAWGRLPVDLAEELGHRDVAR-YLRAAAGGT 137 ++ D WG+ P+ LA GH ++ L+ A Sbjct: 63 DVNAADLWGQTPLHLAATAGHLEIVEVLLKYGADVN 98 >5CBO-A nrPDB Length = 176 Score = 148 bits (374), Expect = 9e-37, Method: Composition-based stats. Identities = 40/119 (33%), Positives = 67/119 (56%), Gaps = 2/119 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPN 71 L AA G+ +EVR L+ GA NA +++G P+ G + E+LL +GA+ N Sbjct: 4 GKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVTPLHLAAYWGHFEIVEVLLKYGADVN 63 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 +D T P+H AA+ G+L + VL + GA ++ +D +G+ D++ + G+ D+A L Sbjct: 64 ASDATGDT-PLHLAAKWGYLGIVEVLLKYGADVNAQDKFGKTAFDISIDNGNEDLAEIL 121 Score = 100 bits (250), Expect = 2e-22, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 46/96 (47%), Gaps = 2/96 (2%) Query: 43 SYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 G++ ++ G +L+ +GA+ N D +T P+H AA G + + VL + GA Sbjct: 2 DLGKKLLEAAHAGQDDEVRILMANGADVNAMDNFGVT-PLHLAAYWGHFEIVEVLLKYGA 60 Query: 103 RLDVRDAWGRLPVDLAEELGHRDVAR-YLRAAAGGT 137 ++ DA G P+ LA + G+ + L+ A Sbjct: 61 DVNASDATGDTPLHLAAKWGYLGIVEVLLKYGADVN 96 >5H76-A nrPDB Length = 201 Score = 145 bits (367), Expect = 6e-36, Method: Composition-based stats. Identities = 39/116 (33%), Positives = 67/116 (57%), Gaps = 3/116 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA G +E V LL+ GA +A + +G P+ G + E+LL +GA+ N D Sbjct: 43 LHLAAYSGHLEIVEVLLKHGADVDASDVFGYTPLHLAAYWGHLEIVEVLLKNGADVNAMD 102 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 +T P+H AA+ G+L+ + VL + GA ++ +D +G+ D++ + G+ D+A+ L Sbjct: 103 SDGMT-PLHLAAKWGYLEIVEVLLKHGA-VNAQDKFGKTAFDISIDNGNEDLAQIL 156 Score = 145 bits (365), Expect = 1e-35, Method: Composition-based stats. Identities = 43/133 (32%), Positives = 68/133 (51%), Gaps = 3/133 (2%) Query: 6 GSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLL 64 GS M+ L AA G+ +EVR L+ GA NA ++ G P+ + G + E+LL Sbjct: 1 GSHMDL-GRKLLEAARAGQDDEVRILMANGADVNAADNTGTTPLHLAAYSGHLEIVEVLL 59 Query: 65 LHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHR 124 HGA+ + +D T P+H AA G L+ + VL + GA ++ D+ G P+ LA + G+ Sbjct: 60 KHGADVDASDVFGYT-PLHLAAYWGHLEIVEVLLKNGADVNAMDSDGMTPLHLAAKWGYL 118 Query: 125 DVARYLRAAAGGT 137 ++ L Sbjct: 119 EIVEVLLKHGAVN 131 >1D9S-A nrPDB Length = 136 Score = 144 bits (363), Expect = 2e-35, Method: Composition-based stats. Identities = 107/120 (89%), Positives = 111/120 (92%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADP 75 LATAAARG+VE VR LLEAGA PNA N +GRRPIQVMMMGSA+VAELLLLHGAEPNCADP Sbjct: 16 LATAAARGQVETVRQLLEAGADPNALNRFGRRPIQVMMMGSAQVAELLLLHGAEPNCADP 75 Query: 76 ATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 ATLTRPVHDAAREGFLDTLVVLHRAGARLDV DAWGRLPVDLAEE GHRD+ARYL AA G Sbjct: 76 ATLTRPVHDAAREGFLDTLVVLHRAGARLDVCDAWGRLPVDLAEEQGHRDIARYLHAATG 135 >1G3N-B nrPDB Length = 168 Score = 142 bits (359), Expect = 5e-35, Method: Composition-based stats. Identities = 55/139 (39%), Positives = 77/139 (55%), Gaps = 1/139 (0%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAE 69 EP + LA+AAARG +E++ +LL+ NA N +GR +QVM +G+ +A LLL GA Sbjct: 3 EPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGAN 62 Query: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129 P+ D +HDAAR GFLDTL L A +++ D G LP+ LA + GH V + Sbjct: 63 PDLKDRTGFAV-IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEF 121 Query: 130 LRAAAGGTRGSNHARIDAA 148 L G + + D A Sbjct: 122 LVKHTASNVGHRNHKGDTA 140 >4Z68-A nrPDB Length = 155 Score = 136 bits (343), Expect = 4e-33, Method: Composition-based stats. Identities = 42/117 (35%), Positives = 59/117 (50%), Gaps = 3/117 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA RV V LL+ GA +A + G P+ G VAELL+ HGA N AD Sbjct: 41 LHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVAD 100 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 T P+H+AA +G + +L + GA ++ G P+DL ++ G D+ LR Sbjct: 101 LWKFT-PLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLR 155 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 11/150 (7%) Query: 15 WLATAAARGRVEEVRALLEAGALPNAPNSYGR--RPIQ-VMMMGSARVAELLLLHGAEPN 71 L AA G VE V+ L + N + GR P+ V E LL HGA+ + Sbjct: 6 QLLEAAKAGDVETVKKLCTVQS-VNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVH 64 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 D L P+H+A G + +L + GA ++V D W P+ A G ++ + L Sbjct: 65 AKDKGGL-VPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLL 123 Query: 132 AAAGGTRGSNHARIDA-----AEGPSDIPD 156 G + + +G +DI D Sbjct: 124 QH-GADPTKKNRDGNTPLDLVKDGDTDIQD 152 >1BLX-B nrPDB Length = 166 Score = 131 bits (329), Expect = 1e-31, Method: Composition-based stats. Identities = 63/134 (47%), Positives = 76/134 (56%), Gaps = 4/134 (2%) Query: 13 ADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPN 71 D L+ AAARG V+EVR LL + P+A N +G+ +QVMM GS VA LL GA PN Sbjct: 9 GDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPN 68 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 D A+ T PVHDAAR GFLDTL VL GA ++ D+ G LP+ LA GH V +L Sbjct: 69 VQD-ASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFL- 126 Query: 132 AAAGGTRGSNHARI 145 A A Sbjct: 127 -APESDLHHRDASG 139 >3ZKJ-A nrPDB Length = 261 Score = 130 bits (326), Expect = 3e-31, Method: Composition-based stats. Identities = 37/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAELLLLHGAEPNCAD 74 L A G + V+ LL+ GA N + P+ + GS LLL HGA Sbjct: 40 LHEACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASV--QP 97 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHR-DVARYLRAA 133 + L P+H+AAR G ++ + L G +D + + P+ LA E R V + L + Sbjct: 98 ESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESG 157 Query: 134 AGGTRGS 140 A +G Sbjct: 158 ADVNQGK 164 Score = 75.1 bits (183), Expect = 1e-14, Method: Composition-based stats. Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 6/116 (5%) Query: 6 GSSMEPSAD---WLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSAR-VAE 61 G+S++P +D + AA RG VE V +L+ G + S+ P+ + R + Sbjct: 92 GASVQPESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVK 151 Query: 62 LLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 LL GA+ N P+H AR + +L GA ++A G+ PV+L Sbjct: 152 KLLESGADVN--QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 205 Score = 63.5 bits (153), Expect = 3e-11, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 43/131 (32%), Gaps = 4/131 (3%) Query: 12 SADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEP 70 L A G + V LL+ GA P S PI G L+ +G Sbjct: 69 WHTPLFNACVSGSWDCVNLLLQHGASVQ-PESDLASPIHEAARRGHVECVNSLIAYGGNI 127 Query: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 + + L P++ A + L +GA ++ + P+ ++A L Sbjct: 128 DHK-ISHLGTPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASEELACLL 185 Query: 131 RAAAGGTRGSN 141 T+ N Sbjct: 186 MDFGADTQAKN 196 Score = 60.8 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 20/93 (21%), Positives = 33/93 (35%), Gaps = 2/93 (2%) Query: 47 RPIQ-VMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLD 105 P+ + G L+ G N A P+H+A G L + +L + GA+++ Sbjct: 5 SPMHEAAIHGHQLSLRNLISQGWAVNII-TADHVSPLHEACLGGHLSCVKILLKHGAQVN 63 Query: 106 VRDAWGRLPVDLAEELGHRDVARYLRAAAGGTR 138 A P+ A G D L + Sbjct: 64 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ 96 Score = 45.4 bits (106), Expect = 9e-06, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 23/60 (38%) Query: 80 RPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRG 139 P+H+AA G +L L G +++ A P+ A GH + L G Sbjct: 5 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 64 >1BD8-A nrPDB Length = 156 Score = 130 bits (326), Expect = 3e-31, Method: Composition-based stats. Identities = 64/135 (47%), Positives = 80/135 (59%), Gaps = 4/135 (2%) Query: 12 SADWLATAAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEP 70 + D L+ AAARG V+EVR LL + P+A N +G+ +QVMM GS +A LL GA P Sbjct: 2 AGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASP 61 Query: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 N D + T PVHDAAR GFLDTL VL GA ++V D G LP+ LA + GH V +L Sbjct: 62 NVQDTSG-TSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFL 120 Query: 131 RAAAGGTRGSNHARI 145 A + R AR Sbjct: 121 AAESDLHR--RDARG 133 Score = 51.6 bits (122), Expect = 1e-07, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCAD 74 + AA G ++ ++ L+E GA N P+ G PI + + G V L ++ + D Sbjct: 72 VHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAE-SDLHRRD 130 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRA 100 LT P+ A + G D + +L Sbjct: 131 ARGLT-PLELALQRGAQDLVDILQGH 155 >5JHQ-A nrPDB Length = 482 Score = 126 bits (317), Expect = 4e-30, Method: Composition-based stats. Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 8/136 (5%) Query: 12 SADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEP 70 + L AA GR + V LL+ GA +A + G P+ G A V LLL GA+P Sbjct: 49 KSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADP 108 Query: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAE------ELGHR 124 N D T P+H+AA +G +D +VL + GA ++R+ G+ +DLA+ G Sbjct: 109 NARDNWNYT-PLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEY 167 Query: 125 DVARYLRAAAGGTRGS 140 L AA G Sbjct: 168 KKDELLEAARSGNEEK 183 Score = 123 bits (310), Expect = 2e-29, Method: Composition-based stats. Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA RV V+ LL+ GA +A + G P+ G V ELLL HGA N D Sbjct: 206 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 265 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H+AA + ++ +L GA + + G+ VD+A Sbjct: 266 LWQFT-PLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 308 Score = 111 bits (278), Expect = 1e-25, Method: Composition-based stats. Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 5/138 (3%) Query: 2 EPAAGSSM--EPSADWLATAAARGRVEEVRALLEA-GALPNAPNSYGRRPIQVMM-MGSA 57 +P+A + + E D L AA G E++ ALL +A + P+ + Sbjct: 156 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 215 Query: 58 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 R+ +LLL HGA+ + D L P+H+A G + +L + GA ++ D W P+ Sbjct: 216 RIVQLLLQHGADVHAKDKGGL-VPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHE 274 Query: 118 AEELGHRDVARYLRAAAG 135 A +V L + Sbjct: 275 AASKNRVEVCSLLLSHGA 292 Score = 100 bits (248), Expect = 3e-22, Method: Composition-based stats. Identities = 37/124 (29%), Positives = 49/124 (39%), Gaps = 5/124 (4%) Query: 15 WLATAAARGRVEEVRALLEAGALPNAPNSYGR--RPIQ-VMMMGSARVAELLLLHGAEPN 71 L A G V V+ L+ A NA + GR P+ G V E LL GA + Sbjct: 18 ELLEACRNGDVSRVKRLV-DAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVH 76 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 D L P+H+A G + + +L GA + RD W P+ A G DV L Sbjct: 77 ARDDGGLI-PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLL 135 Query: 132 AAAG 135 Sbjct: 136 QHGA 139 Score = 83.9 bits (206), Expect = 3e-17, Method: Composition-based stats. Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 5/131 (3%) Query: 8 SMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMG-SA---RVAELL 63 + E L AA + +V+ L + + + +V ELL Sbjct: 318 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVTELL 377 Query: 64 LLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGH 123 L GA N + +T P+H AA D + VLH+ GA+++ D G+ + A GH Sbjct: 378 LRKGANVNEKNKDFMT-PLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAGH 436 Query: 124 RDVARYLRAAA 134 R L + Sbjct: 437 LQTCRLLLSYG 447 Score = 76.2 bits (186), Expect = 6e-15, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 6/112 (5%) Query: 24 RVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCADPATLTRPV 82 R + LL GA N N P+ V V E+L HGA+ N D T + Sbjct: 370 RKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTA-L 428 Query: 83 HDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 H AA G L T +L G+ + G A ++G+ V + L + Sbjct: 429 HRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSEST 476 Score = 30.8 bits (68), Expect = 0.25, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 3/48 (6%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELL 63 L AA G ++ R LL G+ P+ + G MG+ V ++L Sbjct: 428 LHRAALAGHLQTCRLLLSYGSDPSIISLQGFT---AAQMGNEAVQQIL 472 >5HKP-A nrPDB Length = 351 Score = 124 bits (311), Expect = 2e-29, Method: Composition-based stats. Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA RV V+ LL+ GA +A + G P+ G V ELLL HGA N D Sbjct: 62 LHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMD 121 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H+AA + ++ +L GA + + G+ VD+A Sbjct: 122 LWQFT-PLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 164 Score = 112 bits (279), Expect = 9e-26, Method: Composition-based stats. Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 5/138 (3%) Query: 2 EPAAGSSM--EPSADWLATAAARGRVEEVRALLEA-GALPNAPNSYGRRPIQVMM-MGSA 57 +P+A + + E D L AA G E++ ALL +A + P+ + Sbjct: 12 DPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRV 71 Query: 58 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 R+ +LLL HGA+ + D L P+H+A G + +L + GA ++ D W P+ Sbjct: 72 RIVQLLLQHGADVHAKDKGGL-VPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHE 130 Query: 118 AEELGHRDVARYLRAAAG 135 A +V L + Sbjct: 131 AASKNRVEVCSLLLSHGA 148 Score = 85.5 bits (210), Expect = 9e-18, Method: Composition-based stats. Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 5/131 (3%) Query: 8 SMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMG-SA---RVAELL 63 + E L AA + +V+ L + + + +VAELL Sbjct: 174 TYEFKGHSLLQAAREADLAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQVAELL 233 Query: 64 LLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGH 123 L GA N + +T P+H AA D + VLH+ GA+++ D+ G+ + A GH Sbjct: 234 LRKGANVNEKNKDFMT-PLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHRAALAGH 292 Query: 124 RDVARYLRAAA 134 R L + Sbjct: 293 LQTCRLLLSYG 303 Score = 76.6 bits (187), Expect = 4e-15, Method: Composition-based stats. Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 6/112 (5%) Query: 24 RVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCADPATLTRPV 82 R + LL GA N N P+ V V E+L HGA+ N D T + Sbjct: 226 RKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTA-L 284 Query: 83 HDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 H AA G L T +L G+ + G A ++G+ V + L + Sbjct: 285 HRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEAVQQILSEST 332 Score = 30.8 bits (68), Expect = 0.24, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 3/48 (6%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELL 63 L AA G ++ R LL G+ P+ + G MG+ V ++L Sbjct: 284 LHRAALAGHLQTCRLLLSYGSDPSIISLQGFT---AAQMGNEAVQQIL 328 >6BY9-A nrPDB Length = 328 Score = 121 bits (303), Expect = 2e-28, Method: Composition-based stats. Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 4/123 (3%) Query: 15 WLATAAARGRVEEVRALLEAGALPNAPNSY--GRRPIQVMM-MGSARVAELLLLHGAEPN 71 L +A +G +++V +L G PN + R P+ G + +L+ GA + Sbjct: 70 QLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 129 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 T P+ +AA L+ + L +AGA +D +DA G + LA + GH +V +YL Sbjct: 130 TCSEDQRT-PLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLL 188 Query: 132 AAA 134 + Sbjct: 189 SNG 191 Score = 92.8 bits (229), Expect = 6e-20, Method: Composition-based stats. Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGA 68 E L AA +E V+ L++AGAL + ++ G + + G V + LL +G Sbjct: 133 EDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQ 192 Query: 69 -EPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVA 127 + NC D T P+ A +D + +L G+ +++RD + + A G D+A Sbjct: 193 MDVNCQDDGGWT-PMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA 251 Query: 128 RYLRAA 133 L AA Sbjct: 252 EILLAA 257 Score = 89.3 bits (220), Expect = 6e-19, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 56/136 (41%), Gaps = 3/136 (2%) Query: 1 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARV 59 ++P + L AA G V+ L++AGA + + R P+ + Sbjct: 91 IDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEA 150 Query: 60 AELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA-RLDVRDAWGRLPVDLA 118 + L+ GA + D T +H AA++G + + L G ++ +D G P+ A Sbjct: 151 VKYLIKAGALVDPKDAEGSTC-LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWA 209 Query: 119 EELGHRDVARYLRAAA 134 E H D+ + L + Sbjct: 210 TEYKHVDLVKLLLSKG 225 Score = 89.3 bits (220), Expect = 6e-19, Method: Composition-based stats. Identities = 35/149 (23%), Positives = 54/149 (36%), Gaps = 8/149 (5%) Query: 5 AGSSMEPSADW----LATAAARGRVEEVRALLEAG-ALPNAPNSYGRRP-IQVMMMGSAR 58 AG+ ++P L AA +G E V+ LL G N + G P I Sbjct: 157 AGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVD 216 Query: 59 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 + +LLL G++ N D +H AA G +D +L A L + G P+ +A Sbjct: 217 LVKLLLSKGSDINIRDNEENIC-LHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIA 275 Query: 119 EELGHRDVARYLRAAAGGTRGSNHARIDA 147 D L + + + Sbjct: 276 ARENRYDCV-VLFLSRDSDVTLKNKEGET 303 Score = 35.4 bits (80), Expect = 0.010, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 15/41 (36%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGS 56 L AA R + V L + N G P+Q + S Sbjct: 272 LHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNS 312 >5GP7-A nrPDB Length = 169 Score = 120 bits (301), Expect = 3e-28, Method: Composition-based stats. Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 5/140 (3%) Query: 6 GSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGR--RPIQVMM-MGSARVAEL 62 GS + L AA +G + V+ L N ++ GR P+ + + VAE Sbjct: 3 GSDLLRGDAALLDAAKKGCLARVQKLCTPE-NINCRDTQGRNSTPLHLAAGYNNLEVAEY 61 Query: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELG 122 LL HGA+ N D L P+H+AA G +D +L + ++ D W P+ A + G Sbjct: 62 LLEHGADVNAQDKGGLI-PLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG 120 Query: 123 HRDVARYLRAAAGGTRGSNH 142 + L A N Sbjct: 121 RTQLCALLLAHGADPTMKNQ 140 Score = 110 bits (276), Expect = 2e-25, Method: Composition-based stats. Identities = 33/104 (31%), Positives = 49/104 (47%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA +E LLE GA NA + G P+ G +A LL+ + N D Sbjct: 47 LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 106 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H+AA++G +L GA +++ G+ P+DLA Sbjct: 107 KWAFT-PLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA 149 >3T9K-A nrPDB Length = 390 Score = 99.7 bits (247), Expect = 4e-22, Method: Composition-based stats. Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 4/105 (3%) Query: 32 LEAGALPNAPNSY--GRRPI-QVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAARE 88 L GA N N P+ Q S E LL +GA N AD A P+H A Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAG-RGPLHHATIL 278 Query: 89 GFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 G + + GA L RD+ GR P+ +A E + D+ LR A Sbjct: 279 GHTGLACLFLKRGADLGARDSEGRDPLTIAMETANADIVTLLRLA 323 Score = 52.7 bits (125), Expect = 6e-08, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 2/83 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAELLLLHGAEPNCAD 74 L A A + LL+ GA N +S GR P+ ++G +A L L GA+ D Sbjct: 239 LIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILGHTGLACLFLKRGADLGARD 298 Query: 75 PATLTRPVHDAAREGFLDTLVVL 97 P+ A D + +L Sbjct: 299 SEG-RDPLTIAMETANADIVTLL 320 Score = 50.8 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 22/83 (26%), Positives = 33/83 (39%), Gaps = 2/83 (2%) Query: 64 LLHGAEPNCADPAT-LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELG 122 L HGA+ N + P+ A L L + GA ++ D+ GR P+ A LG Sbjct: 220 LAHGADVNWVNGGQDNATPLIQATAANSLLACEFLLQNGANVNQADSAGRGPLHHATILG 279 Query: 123 HRDVARYLRAAAGGTRGSNHARI 145 H +A G G+ + Sbjct: 280 HTGLACLFLKR-GADLGARDSEG 301 >5ET1-A nrPDB Length = 353 Score = 97.4 bits (241), Expect = 2e-21, Method: Composition-based stats. Identities = 45/129 (34%), Positives = 56/129 (43%), Gaps = 6/129 (4%) Query: 16 LATAAARGRVEEVRALLEAGALPNA--PNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNC 72 L AA G V L + A + + G + G +V LLLHGAE + Sbjct: 211 LHAAAQMGH-NPVLVWLVSFADVSFSEQDHDGATAMHFAASRGHTKVLSWLLLHGAEIS- 268 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 D T P+HDAA G L+ +L GA LDVRD G DLAE GH +RYLR Sbjct: 269 QDLWGGT-PLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYLRT 327 Query: 133 AAGGTRGSN 141 + Sbjct: 328 VQTLSLEHR 336 Score = 78.9 bits (193), Expect = 8e-16, Method: Composition-based stats. Identities = 36/122 (29%), Positives = 51/122 (41%), Gaps = 3/122 (2%) Query: 19 AAARGRVEEVRALLEAGAL-PNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCADPA 76 AA RG ++ +R+L AG L P+ +S P+ G L+ A P + Sbjct: 10 AARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVSRAR 69 Query: 77 TLTRPVHDAAREGFLDTLVVLHRAGAR-LDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 P HDAA G+L L L G + +D G + LA GH DV ++L G Sbjct: 70 NGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGG 129 Query: 136 GT 137 Sbjct: 130 AN 131 Score = 78.9 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 31/118 (26%), Positives = 52/118 (44%), Gaps = 3/118 (2%) Query: 17 ATAAARGRVEEVRALL-EAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPNCAD 74 AAA G + ++ LL + G ++ G + + G V + LL G + Sbjct: 76 HDAAATGYLSCLQWLLTQGGCRVQEKDNSGATVLHLAARFGHPDVVKWLLYQGGANSAIT 135 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRA-GARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 T P+H AA +G L +L +L ++ + G P+ LA + GH +V +YL Sbjct: 136 TDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNAQTNNGATPLYLACQEGHLEVTKYLV 193 Score = 71.6 bits (174), Expect = 1e-13, Method: Composition-based stats. Identities = 35/136 (25%), Positives = 52/136 (38%), Gaps = 3/136 (2%) Query: 16 LATAAARGRVEEVRALL-EAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCA 73 L AA G + V+ LL + GA G PI G +LL+ H E A Sbjct: 109 LHLAARFGHPDVVKWLLYQGGANSAITTDTGALPIHYAAAKGDLPSLKLLVGHYPEGVNA 168 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHR-AGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 P++ A +EG L+ L + A +R G P+ A ++GH V +L + Sbjct: 169 QTNNGATPLYLACQEGHLEVTKYLVQECSADPHLRAQDGMTPLHAAAQMGHNPVLVWLVS 228 Query: 133 AAGGTRGSNHARIDAA 148 A + A Sbjct: 229 FADVSFSEQDHDGATA 244 Score = 44.2 bits (103), Expect = 2e-05, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 29/101 (28%), Gaps = 1/101 (0%) Query: 48 PIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDV- 106 +Q G V L G + PVH AAR G L L L A V Sbjct: 7 ALQAARRGDLDVLRSLHAAGLLGPSLRDSLDALPVHHAARSGKLHCLRYLVEEVALPAVS 66 Query: 107 RDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDA 147 R G P A G+ ++L G Sbjct: 67 RARNGATPAHDAAATGYLSCLQWLLTQGGCRVQEKDNSGAT 107 Score = 35.0 bits (79), Expect = 0.012, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 17/52 (32%), Gaps = 1/52 (1%) Query: 13 ADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELL 63 L AA G +E + L GA + + G + G + L Sbjct: 274 GTPLHDAAENGELECCQILAVNGAGLDVRDHDGYTAADLAEFNGHTHCSRYL 325 >4NIK-A nrPDB Length = 230 Score = 96.6 bits (239), Expect = 3e-21, Method: Composition-based stats. Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA+ GR E V+ALL GA NA N G P+ +A +LL GA P+ D Sbjct: 81 LHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 140 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 T +H AA +G L + +L A +++D G P+ LA + + A+ L + Sbjct: 141 HYEATA-MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG 199 Query: 135 GG 136 Sbjct: 200 AS 201 Score = 93.9 bits (232), Expect = 2e-20, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 2/123 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L A + G E V LL+ G N + G P+ G + + LL GA+ N + Sbjct: 48 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVN 107 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 T P+H AA + + V+L GA D +D + + A G+ + L Sbjct: 108 QNGCT-PLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYK 166 Query: 135 GGT 137 T Sbjct: 167 AST 169 Score = 84.7 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 30/130 (23%), Positives = 50/130 (38%), Gaps = 3/130 (2%) Query: 20 AARGRVEEV-RALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCADPAT 77 A G++EE+ ++L +L + R + G + E LL G N D A Sbjct: 18 AYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 77 Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGT 137 P+H AA G + + L GA+++ + G P+ A ++A L Sbjct: 78 W-SPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 136 Query: 138 RGSNHARIDA 147 +H A Sbjct: 137 DAKDHYEATA 146 Score = 71.6 bits (174), Expect = 1e-13, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA++ R E LLE GA P+A + Y + G+ ++ +LL + A N D Sbjct: 114 LHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQD 173 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H A E ++ +L GA + + + + P+ +A Sbjct: 174 TEGNT-PLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 216 Score = 51.2 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 31/94 (32%), Gaps = 1/94 (1%) Query: 50 QVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDA 109 + G + +L +H A G + + L + G ++ +D Sbjct: 16 NLAYSGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDD 75 Query: 110 WGRLPVDLAEELGHRDVAR-YLRAAAGGTRGSNH 142 G P+ +A G ++ + L A + + Sbjct: 76 AGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQN 109 Score = 41.2 bits (95), Expect = 2e-04, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 31/76 (40%), Gaps = 2/76 (2%) Query: 11 PSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAE 69 A + AAA+G ++ + LL A N ++ G P+ A+LL+ GA Sbjct: 142 YEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGAS 201 Query: 70 PNCADPATLTRPVHDA 85 + T P+ A Sbjct: 202 IYIENKEEKT-PLQVA 216 Score = 29.6 bits (65), Expect = 0.62, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 18/40 (45%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMG 55 L A RVEE + L+ GA N + P+QV G Sbjct: 180 LHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVAKGG 219 >3B7B-A nrPDB Length = 237 Score = 96.6 bits (239), Expect = 4e-21, Method: Composition-based stats. Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 4/99 (4%) Query: 39 NAPNSY--GRRPIQVMM-MGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLV 95 N + R P+ G + +L+ GA + T P+ +AA L+ + Sbjct: 3 NFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRT-PLMEAAENNHLEAVK 61 Query: 96 VLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 L +AGA +D +DA G + LA + GH +V +YL + Sbjct: 62 YLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG 100 Score = 92.4 bits (228), Expect = 8e-20, Method: Composition-based stats. Identities = 35/126 (27%), Positives = 58/126 (46%), Gaps = 3/126 (2%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGA 68 E L AA +E V+ L++AGAL + ++ G + + G V + LL +G Sbjct: 42 EDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQ 101 Query: 69 -EPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVA 127 + NC D T P+ A +D + +L G+ +++RD + + A G D+A Sbjct: 102 MDVNCQDDGGWT-PMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIA 160 Query: 128 RYLRAA 133 L AA Sbjct: 161 EILLAA 166 Score = 88.9 bits (219), Expect = 8e-19, Method: Composition-based stats. Identities = 35/149 (23%), Positives = 54/149 (36%), Gaps = 8/149 (5%) Query: 5 AGSSMEPSADW----LATAAARGRVEEVRALLEAG-ALPNAPNSYGRRP-IQVMMMGSAR 58 AG+ ++P L AA +G E V+ LL G N + G P I Sbjct: 66 AGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVD 125 Query: 59 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 + +LLL G++ N D +H AA G +D +L A L + G P+ +A Sbjct: 126 LVKLLLSKGSDINIRDNEENIC-LHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIA 184 Query: 119 EELGHRDVARYLRAAAGGTRGSNHARIDA 147 D L + + + Sbjct: 185 ARENRYDCV-VLFLSRDSDVTLKNKEGET 212 Score = 88.5 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 3/125 (2%) Query: 12 SADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAELLLLHGAEP 70 L AA G V+ L++AGA + + R P+ + + L+ GA Sbjct: 11 KRSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALV 70 Query: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGA-RLDVRDAWGRLPVDLAEELGHRDVARY 129 + D T +H AA++G + + L G ++ +D G P+ A E H D+ + Sbjct: 71 DPKDAEGSTC-LHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKL 129 Query: 130 LRAAA 134 L + Sbjct: 130 LLSKG 134 Score = 57.7 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 19/57 (33%), Positives = 27/57 (47%) Query: 79 TRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAG 135 P+H AA G +D +L +AGA +D R P+ A E H + +YL A Sbjct: 12 RSPLHAAAEAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGA 68 Score = 35.4 bits (80), Expect = 0.011, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 15/41 (36%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGS 56 L AA R + V L + N G P+Q + S Sbjct: 181 LHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCASLNS 221 >2DWZ-A nrPDB Length = 231 Score = 96.2 bits (238), Expect = 5e-21, Method: Composition-based stats. Identities = 39/122 (31%), Positives = 57/122 (46%), Gaps = 2/122 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA+ GR E V+ALL GA NA N G P+ +A +LL GA P+ D Sbjct: 77 LHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKD 136 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 T +H AA +G L + +L A +++D G P+ LA + + A++L Sbjct: 137 HYDATA-MHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQG 195 Query: 135 GG 136 Sbjct: 196 AS 197 Score = 94.3 bits (233), Expect = 2e-20, Method: Composition-based stats. Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 2/123 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L A + G E V LL+ G N + G P+ G + + LL+ GA N + Sbjct: 44 LHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLVKGAHVNAVN 103 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAA 134 T P+H AA + + V+L GA D +D + + A G+ + L Sbjct: 104 QNGCT-PLHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYK 162 Query: 135 GGT 137 T Sbjct: 163 AST 165 Score = 84.7 bits (208), Expect = 2e-17, Method: Composition-based stats. Identities = 28/126 (22%), Positives = 47/126 (37%), Gaps = 3/126 (2%) Query: 20 AARGRVEEV-RALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCADPAT 77 A G+++E+ +L +L + R + G + E LL G N D A Sbjct: 14 AYSGKLDELKERILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAG 73 Query: 78 LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGT 137 P+H AA G + + L GA ++ + G P+ A ++A L Sbjct: 74 W-SPLHIAASAGRDEIVKALLVKGAHVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANP 132 Query: 138 RGSNHA 143 +H Sbjct: 133 DAKDHY 138 Score = 72.4 bits (176), Expect = 9e-14, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCAD 74 L AA++ R E LLE GA P+A + Y + G+ ++ +LL + A N D Sbjct: 110 LHYAASKNRHEIAVMLLEGGANPDAKDHYDATAMHRAAAKGNLKMVHILLFYKASTNIQD 169 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 T P+H A E ++ L GA + + + + P+ +A Sbjct: 170 TEGNT-PLHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVA 212 Score = 51.2 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 36/95 (37%), Gaps = 3/95 (3%) Query: 50 QVMMMGSA-RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRD 108 + G + E +L + D + T +H A G + + L + G ++ +D Sbjct: 12 NLAYSGKLDELKERILADKSLATRTDQDSRTA-LHWACSAGHTEIVEFLLQLGVPVNDKD 70 Query: 109 AWGRLPVDLAEELGHRDVAR-YLRAAAGGTRGSNH 142 G P+ +A G ++ + L A + + Sbjct: 71 DAGWSPLHIAASAGRDEIVKALLVKGAHVNAVNQN 105 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 11 PSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAE 69 A + AAA+G ++ V LL A N ++ G P+ A+ L+ GA Sbjct: 138 YDATAMHRAAAKGNLKMVHILLFYKASTNIQDTEGNTPLHLACDEERVEEAKFLVTQGAS 197 Query: 70 PNCADPATLTRPVHDA 85 + T P+ A Sbjct: 198 IYIENKEEKT-PLQVA 212 Score = 30.0 bits (66), Expect = 0.50, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 21/48 (43%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELL 63 L A RVEE + L+ GA N + P+QV G + + L Sbjct: 176 LHLACDEERVEEAKFLVTQGASIYIENKEEKTPLQVAKGGLGLILKRL 223 >3EU9-A nrPDB Length = 240 Score = 85.5 bits (210), Expect = 8e-18, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 53/136 (38%), Gaps = 5/136 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPNCAD 74 L A +G + V L++ GA P+ + G I + G + L+ G + + D Sbjct: 80 LHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVDMMD 139 Query: 75 PATLTRPVHDAAREGF-LDTLVVLHRAGARLDVRDA-WGRLPVDLAEELGHRDVARYLRA 132 +T P+ AA +D +L +++ D + A G+ V L Sbjct: 140 QNGMT-PLMWAAYRTHSVDPTRLLLTFNVSVNLGDKYHKNTALHWAVLAGNTTVISLL-L 197 Query: 133 AAGGTRGSNHARIDAA 148 AG + + + ++A Sbjct: 198 EAGANVDAQNIKGESA 213 Score = 79.3 bits (194), Expect = 6e-16, Method: Composition-based stats. Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 1/126 (0%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGS-ARVAELLLLHGA 68 + S + A G E R L+EAG P+ + + + + + + GA Sbjct: 7 DYSTWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGA 66 Query: 69 EPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVAR 128 + + P+H A R+G L +V L + GA + D G + LA + GH + Sbjct: 67 IVDQLGGDLNSTPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVA 126 Query: 129 YLRAAA 134 YL A Sbjct: 127 YLIAKG 132 Score = 73.5 bits (179), Expect = 4e-14, Method: Composition-based stats. Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 2/120 (1%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM--GSARVAELLLLHGAEPNCA 73 + AA G V L+ G + + G P+ S LLL N Sbjct: 113 IHLAAQFGHTSIVAYLIAKGQDVDMMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLG 172 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 D +H A G + +L AGA +D ++ G +DLA++ + + +L+ A Sbjct: 173 DKYHKNTALHWAVLAGNTTVISLLLEAGANVDAQNIKGESALDLAKQRKNVWMINHLQEA 232 Score = 51.6 bits (122), Expect = 1e-07, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 31/89 (34%), Gaps = 3/89 (3%) Query: 49 IQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRD 108 ++ G L+ G + D +T +H AA +D + GA +D Sbjct: 14 VKATQYGIYERCRELVEAGYDVRQPDKENVTL-LHWAAINNRIDLVKYYISKGAIVDQLG 72 Query: 109 AWGR-LPVDLAEELGHRD-VARYLRAAAG 135 P+ A GH V + ++ A Sbjct: 73 GDLNSTPLHWATRQGHLSMVVQLMKYGAD 101 >4OAU-C nrPDB Length = 699 Score = 80.4 bits (197), Expect = 3e-16, Method: Composition-based stats. Identities = 35/133 (26%), Positives = 49/133 (36%), Gaps = 3/133 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS-YGRRPIQ-VMMMGSARVAELLLLHGAEPNCA 73 L A V+ V+ LLE GA N G P+ + M + ELLL HGA+P Sbjct: 9 LIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLR 68 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAA 133 T P AA G + L + GA ++ D +G A G ++L Sbjct: 69 KKNGAT-PFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKR 127 Query: 134 AGGTRGSNHARID 146 + D Sbjct: 128 GANVNLRRKTKED 140 Score = 79.7 bits (195), Expect = 5e-16, Method: Composition-based stats. Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 8/129 (6%) Query: 16 LATAAARGRVEEVRALL-EAGALPNAPNSYGRRPIQVMMMGSAR-----VAELLLLHGAE 69 L AA +G VE ++ LL E GA NA ++ GR + ++ S + LLL HGA+ Sbjct: 152 LMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGAD 211 Query: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAG-ARLDVRDAWGRLPVDLAEELGHRDVAR 128 N T P+ A + L + L ++ D+ G+ + LA EL + +A Sbjct: 212 VNVRGERGKT-PLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAE 270 Query: 129 YLRAAAGGT 137 L T Sbjct: 271 LLCKRGAST 279 Score = 76.2 bits (186), Expect = 6e-15, Method: Composition-based stats. Identities = 31/146 (21%), Positives = 54/146 (36%), Gaps = 15/146 (10%) Query: 18 TAAARGRVEEVRALLEAGALPNAPNS----------YGRRPI-QVMMMGSARVAELLL-L 65 AA G+V+ ++ L + GA N G + G V ++LL Sbjct: 111 EAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDE 170 Query: 66 HGAEPNCADPATLTRPVH--DAAREGFLD-TLVVLHRAGARLDVRDAWGRLPVDLAEELG 122 GA+ N D +H ++ + ++ +L GA ++VR G+ P+ LA E Sbjct: 171 MGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKK 230 Query: 123 HRDVARYLRAAAGGTRGSNHARIDAA 148 H + + L + A Sbjct: 231 HLGLVQRLLEQEHIEINDTDSDGKTA 256 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 37/95 (38%), Gaps = 8/95 (8%) Query: 10 EPSADWLATAAARGRVEEVRALLEAG-ALPNAPNSYGRRPIQVMMMGSAR-VAELLLLHG 67 E L A + + V+ LLE N +S G+ + + + + +AELL G Sbjct: 217 ERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRG 276 Query: 68 AEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 A +C D V A R + VL GA Sbjct: 277 ASTDCGDL------VMTARRNYDHSLVKVLLSHGA 305 >5DND-A nrPDB Length = 588 Score = 78.1 bits (191), Expect = 1e-15, Method: Composition-based stats. Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 1/117 (0%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMG-SARVAELLLLHGAEPNCAD 74 L AA GR V LL G NA + G P+ + + G LL GA + D Sbjct: 459 LHVAARNGRDGVVTMLLHRGMDVNARDRDGLSPLLLAVQGRHRECIRLLRKAGACLSPQD 518 Query: 75 PATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 + A ++ L +AGA L GR + +AE G+++V LR Sbjct: 519 LKDAGTELCRLASRADMEGLQAWGQAGADLQQPGYDGRSALCVAEAAGNQEVLALLR 575 Score = 68.5 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 1/88 (1%) Query: 48 PIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVR 107 + + G + L+ G++ D T +H AAR G + +L G ++ R Sbjct: 426 ALALAHAGELEALQALMELGSDLRLKDSNGQTL-LHVAARNGRDGVVTMLLHRGMDVNAR 484 Query: 108 DAWGRLPVDLAEELGHRDVARYLRAAAG 135 D G P+ LA + HR+ R LR A Sbjct: 485 DRDGLSPLLLAVQGRHRECIRLLRKAGA 512 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 33/127 (25%), Positives = 55/127 (43%), Gaps = 5/127 (3%) Query: 16 LATA-AARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAEPNCA 73 LA A A G +E ++AL+E G+ +S G+ + V G V +LL G + N Sbjct: 425 LALALAHAGELEALQALMELGSDLRLKDSNGQTLLHVAARNGRDGVVTMLLHRGMDVNAR 484 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRD-AWGRLPV-DLAEELGHRDVARYLR 131 D L P+ A + + + +L +AGA L +D + LA + + + Sbjct: 485 DRDGL-SPLLLAVQGRHRECIRLLRKAGACLSPQDLKDAGTELCRLASRADMEGLQAWGQ 543 Query: 132 AAAGGTR 138 A A + Sbjct: 544 AGADLQQ 550 >6AUN-A nrPDB Length = 752 Score = 77.7 bits (190), Expect = 2e-15, Method: Composition-based stats. Identities = 27/129 (20%), Positives = 49/129 (37%), Gaps = 5/129 (3%) Query: 9 MEPSADWLATAAARGRVEEVRALLE-AGALPNAPN-SYGRRPIQVMMMGSARVAELLLLH 66 M PS + TA + ++ + ++ + YG P+ +A +A +LL Sbjct: 249 MGPSGFPIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAK--NAEMARMLLKR 306 Query: 67 GAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDV 126 G + + A T +H A D ++VL GA G P+ LA + ++ Sbjct: 307 GCDVDSTSAAGNTA-LHVAVMRNRFDCVMVLLTYGANAGTPGEHGNTPLHLAISKDNMEM 365 Query: 127 ARYLRAAAG 135 + L Sbjct: 366 IKALIVFGA 374 Score = 71.2 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 28/118 (23%), Positives = 48/118 (40%), Gaps = 5/118 (4%) Query: 7 SSMEPSADWLATAA---ARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAEL 62 SS S D A+ E R LL+ G ++ ++ G + V +M + Sbjct: 276 SSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDVDSTSAAGNTALHVAVMRNRFDCVMV 335 Query: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 LL +GA T P+H A + ++ + L GA +D + +G P +A + Sbjct: 336 LLTYGANAGTPGEHGNT-PLHLAISKDNMEMIKALIVFGAEVDTPNDFGETPAFMASK 392 Score = 62.7 bits (151), Expect = 7e-11, Method: Composition-based stats. Identities = 31/136 (22%), Positives = 56/136 (41%), Gaps = 5/136 (3%) Query: 16 LATAAARGRVEEVRALLEA-GALPNAPNSYGRRPIQVMMMG-SARVAELLLLHG-AEPNC 72 L A +G E + L++ A + ++ G + G +++V +LL + A N Sbjct: 156 LHLACRKGDSEILVELVQYCHAQMDVTDNKGETAFHYAVQGDNSQVLQLLGKNASAGLNQ 215 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 + LT P+H A + G + + VL AR +V G P+ A + + A + + Sbjct: 216 VNKQGLT-PLHLACQMGKQEMVRVLLLCNARCNVMGPSGF-PIHTAMKFSQKGCAEMIIS 273 Query: 133 AAGGTRGSNHARIDAA 148 S R A+ Sbjct: 274 MDSSQIHSKDPRYGAS 289 Score = 61.2 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 46/163 (28%), Gaps = 38/163 (23%) Query: 20 AARGRVEEVRALLEAGAL--PNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCADPA 76 A +G +V LL A N N G P+ MG + +LLL A N P+ Sbjct: 193 AVQGDNSQVLQLLGKNASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLCNARCNVMGPS 252 Query: 77 TLTRPVHDAAREGFLDTLVV--------------------------------LHRAGARL 104 P+H A + + L + G + Sbjct: 253 GF--PIHTAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCDV 310 Query: 105 DVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDA 147 D A G + +A D L G G+ + Sbjct: 311 DSTSAAGNTALHVAVMRNRFDCVMVLLTY-GANAGTPGEHGNT 352 Score = 55.0 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 13/117 (11%) Query: 42 NSYGRRPIQ-VMMMGSARVAELLLLH-GAEPNCADPATLTRPVHDAAREGFLDTLVVLHR 99 N G P+ G + + L+ + A+ + D T H A + L +L + Sbjct: 149 NEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETA-FHYAVQGDNSQVLQLLGK 207 Query: 100 AG-ARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIP 155 A L+ + G P+ LA ++G +++ R L +AR + GPS P Sbjct: 208 NASAGLNQVNKQGLTPLHLACQMGKQEMVRVLLLC--------NARCNVM-GPSGFP 255 Score = 31.9 bits (71), Expect = 0.13, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 34/118 (28%), Gaps = 3/118 (2%) Query: 32 LEAGALPNAPNSYGRRPIQVMMMGSARVAEL-LLLHGAEPNCADPATLTRPVHDAAREGF 90 LE+ A + S +V + +L H ++ + P+ H A G Sbjct: 74 LESEADALVNFQQFSSQLPPFYESSVQVLHVEVLQHLSDLIRSHPSWTVT--HLAVELGI 131 Query: 91 LDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAA 148 + + G P+ LA G ++ L + + A Sbjct: 132 RECFHHSRIISCANSTENEEGCTPLHLACRKGDSEILVELVQYCHAQMDVTDNKGETA 189 >4O1O-A nrPDB Length = 717 Score = 76.6 bits (187), Expect = 4e-15, Method: Composition-based stats. Identities = 39/148 (26%), Positives = 54/148 (36%), Gaps = 9/148 (6%) Query: 1 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSY-GRRPIQVMM-MGSAR 58 M+PA+ M L A +E+VR LLE GA N G P+ + M S Sbjct: 3 MDPASLEEM------LTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSED 56 Query: 59 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 118 + LLL HGA+P T P A G + L +L ++ D G A Sbjct: 57 LVALLLKHGADPCLRKRNGAT-PFIIAGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEA 115 Query: 119 EELGHRDVARYLRAAAGGTRGSNHARID 146 G + R+L + D Sbjct: 116 AVYGRVEALRFLYENGADVNMHRKTKQD 143 Score = 75.4 bits (184), Expect = 9e-15, Method: Composition-based stats. Identities = 35/129 (27%), Positives = 55/129 (42%), Gaps = 8/129 (6%) Query: 16 LATAAARGRVEEVRALLEA-GALPNAPNSYGRRPIQVMMMGSAR-----VAELLLLHGAE 69 L AA +G V V LL A A +A ++ GR + ++ + LLL HGA+ Sbjct: 155 LMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKAKAITRLLLDHGAD 214 Query: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRA-GARLDVRDAWGRLPVDLAEELGHRDVAR 128 N + T P+ A LD + +L ++ D G+ + LA EL ++A+ Sbjct: 215 VNVRGEGSKT-PLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELRLEEIAK 273 Query: 129 YLRAAAGGT 137 L T Sbjct: 274 LLCHRGAST 282 Score = 67.3 bits (163), Expect = 2e-12, Method: Composition-based stats. Identities = 29/178 (16%), Positives = 49/178 (27%), Gaps = 48/178 (26%) Query: 19 AAARGRVEEVRALLEAGALPNAPNSYGRRP-IQVMMMGSARVAELLLLHGAEPNC----- 72 A G V ++ LL N + G ++ + G L +GA+ N Sbjct: 82 AGITGNVRLLQLLLPNVEDVNECDVNGFTAFMEAAVYGRVEALRFLYENGADVNMHRKTK 141 Query: 73 ADPA----TLTRPVHDAAREGFLDTL---------------------------------- 94 D + DAA +G + + Sbjct: 142 QDQERIRKGGATALMDAAEKGHVGVVTILLHAMKAEVDARDNMGRNALVYALLNPDDGKA 201 Query: 95 ----VVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAA 148 +L GA ++VR + P+ LA E + D+ + L A Sbjct: 202 KAITRLLLDHGADVNVRGEGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTA 259 Score = 42.7 bits (99), Expect = 7e-05, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVR-DAWGRLPVDLAEELGHRDVARYL 130 DPA+L + A +E ++ + L GA + + + WG P+ A ++ D+ L Sbjct: 2 AMDPASLEEMLTQAVQEADIEQVRQLLERGADANFQEEEWGWSPLHSAVQMDSEDLVALL 61 Query: 131 RAAAG 135 Sbjct: 62 LKHGA 66 Score = 37.7 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 10/101 (9%) Query: 10 EPSADWLATAAARGRVEEVRALLEAG-ALPNAPNSYGRRPIQVMMMGSAR-VAELLLLHG 67 E S L A R ++ V+ LLE N + G+ + + + +A+LL G Sbjct: 220 EGSKTPLILAVERKNLDLVQMLLEQEQIEVNDTDREGKTALLLAVELRLEEIAKLLCHRG 279 Query: 68 AEPNCADPATLTRPVHDAAREGF-LDTLVVLHRAGARLDVR 107 A NC D + AR + D + L A D R Sbjct: 280 ASTNCGDLVAI-------ARRNYDSDLVKFLRLHKAGEDFR 313 >3EHQ-A nrPDB Length = 222 Score = 75.1 bits (183), Expect = 1e-14, Method: Composition-based stats. Identities = 33/130 (25%), Positives = 53/130 (40%), Gaps = 6/130 (4%) Query: 10 EPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLH-G 67 E + L AA RG + +R L+ N + G + G + E+L Sbjct: 71 ESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLFTQPN 130 Query: 68 AEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVA 127 E N + T +H AA +G+ D + +L GAR D+R+ +L D+A + A Sbjct: 131 IELNQQNKLGDTA-LHAAAWKGYADIVQLLLAKGARTDLRNIEKKLAFDMAT---NAACA 186 Query: 128 RYLRAAAGGT 137 L+ G Sbjct: 187 SLLKKKQGTD 196 Score = 53.1 bits (126), Expect = 5e-08, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 27/77 (35%) Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 ++ P+H+AA+ G L L ++ D G + A GH+D+ L Sbjct: 67 AEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEMLF 126 Query: 132 AAAGGTRGSNHARIDAA 148 + D A Sbjct: 127 TQPNIELNQQNKLGDTA 143 >5D68-A nrPDB Length = 486 Score = 73.9 bits (180), Expect = 3e-14, Method: Composition-based stats. Identities = 32/124 (25%), Positives = 48/124 (38%), Gaps = 7/124 (5%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHG-AEPNCA 73 L +A G E + LL N +S PI G +LL G PN Sbjct: 42 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 101 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRA-GARLDVRDAWGRLPVDLAEELGH---RDVARY 129 L+ P+H AA G + + +L + D GR P+++ EE + A+ Sbjct: 102 -NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 160 Query: 130 LRAA 133 L+ A Sbjct: 161 LKEA 164 Score = 55.4 bits (132), Expect = 1e-08, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 32/93 (34%), Gaps = 3/93 (3%) Query: 48 PIQ-VMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGAR-LD 105 P+ G + + LL N D P+H A G ++ +L G + Sbjct: 41 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWA-PIHYACWYGKVEATRILLEKGKCNPN 99 Query: 106 VRDAWGRLPVDLAEELGHRDVARYLRAAAGGTR 138 + + P+ A GH ++ + L R Sbjct: 100 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDR 132 >2KXP-C nrPDB Length = 118 Score = 73.1 bits (178), Expect = 5e-14, Method: Composition-based stats. Identities = 28/102 (27%), Positives = 43/102 (42%), Gaps = 2/102 (1%) Query: 15 WLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNCA 73 A G ++EV+ + G N GR+P+ G + E LLL GA+ N Sbjct: 5 EFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAP 64 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPV 115 D +T P+ A EG + + +L GA V+ G + Sbjct: 65 DKHHIT-PLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAL 105 Score = 60.0 bits (144), Expect = 4e-10, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 31/85 (36%), Gaps = 1/85 (1%) Query: 51 VMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAW 110 + G + + G + N +P+H AA G L+ L L GA ++ D Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRT-LEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKH 67 Query: 111 GRLPVDLAEELGHRDVARYLRAAAG 135 P+ A GH + L + Sbjct: 68 HITPLLSAVYEGHVSCVKLLLSKGA 92 Score = 55.8 bits (133), Expect = 8e-09, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 8 SMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLH 66 ++E L AA G++E + LL GA NAP+ + P+ + G +LLL Sbjct: 31 TLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSK 90 Query: 67 GAEPNCADPATLTR 80 GA+ P LT Sbjct: 91 GADKTVKGPDGLTA 104 Score = 38.1 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%), Gaps = 1/60 (1%) Query: 85 AAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVAR-YLRAAAGGTRGSNHA 143 A + G LD + G ++ GR P+ A + G ++ L A H Sbjct: 9 ALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHH 68 Score = 32.3 bits (72), Expect = 0.086, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 14/37 (37%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVM 52 L +A G V V+ LL GA G ++ Sbjct: 72 LLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEAT 108 >1WG0-A nrPDB Length = 243 Score = 71.2 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 5/137 (3%) Query: 17 ATAAARGRVEEVRALLEAGA--LPNAPNSYGRRPIQVMMMGSA-RVAELLLLHGAEPNCA 73 A + G +E V++L + N + G + + + V++ L+ +GA Sbjct: 77 HIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASVRIK 136 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAG-ARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 D P+H AA G L + +L G + ++ +D G P+ A GH D A L Sbjct: 137 DKFNQI-PLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVE 195 Query: 133 AAGGTRGSNHARIDAAE 149 G + AE Sbjct: 196 KYGAEYDLVDNKGAKAE 212 Score = 56.2 bits (134), Expect = 6e-09, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 44/121 (36%), Gaps = 7/121 (5%) Query: 16 LATAAARGRVEEVRALLEAGALPNA---PNSYGRRPIQ-VMMMGSARVAELLLLH--GAE 69 L + + E LL N P+ G P +G+ V + L + Sbjct: 40 LHWSVSFQAHEITSFLLSKMENVNLDDYPDDSGWTPFHIACSVGNLEVVKSLYDRPLKPD 99 Query: 70 PNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129 N +T +H A + + + L GA + ++D + ++P+ A +G + Sbjct: 100 LNKITNQGVTC-LHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIEL 158 Query: 130 L 130 L Sbjct: 159 L 159 Score = 39.2 bits (90), Expect = 7e-04, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 27/87 (31%), Gaps = 4/87 (4%) Query: 48 PIQ-VMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDV 106 P+ M + LL P+H + + L +++ Sbjct: 5 PLHQACMENEFFKVQELLHSKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNL 64 Query: 107 ---RDAWGRLPVDLAEELGHRDVARYL 130 D G P +A +G+ +V + L Sbjct: 65 DDYPDDSGWTPFHIACSVGNLEVVKSL 91 >3UI2-A nrPDB Length = 244 Score = 69.3 bits (168), Expect = 7e-13, Method: Composition-based stats. Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 3/118 (2%) Query: 4 AAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAEL 62 AA E W TAA + + + LLE +A + GR + V +GS + L Sbjct: 38 AADVVSEYETPW-WTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRL 95 Query: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 L GA+ + D +H AA + + L GA ++V D G ++LA E Sbjct: 96 LAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELARE 153 Score = 32.3 bits (72), Expect = 0.097, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 21/66 (31%), Gaps = 2/66 (3%) Query: 80 RPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRG 139 P AAR+ L L +D D GR + LG R L A AG Sbjct: 47 TPWWTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRLL-AEAGADLD 104 Query: 140 SNHARI 145 R Sbjct: 105 HRDMRG 110 >3DEO-A nrPDB Length = 183 Score = 68.9 bits (167), Expect = 8e-13, Method: Composition-based stats. Identities = 33/118 (27%), Positives = 50/118 (42%), Gaps = 3/118 (2%) Query: 4 AAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAEL 62 AA E W TAA + + + LLE +A + GR + V +GS + L Sbjct: 37 AADVVSEYETPW-WTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRL 94 Query: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEE 120 L GA+ + D +H AA + + L GA ++V D G ++LA E Sbjct: 95 LAEAGADLDHRDMRGGLTALHMAAGYVRPEVVEALVELGADIEVEDERGLTALELARE 152 Score = 32.3 bits (72), Expect = 0.100, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 21/66 (31%), Gaps = 2/66 (3%) Query: 80 RPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGTRG 139 P AAR+ L L +D D GR + LG R L A AG Sbjct: 46 TPWWTAARKADEQALSQLLED-RDVDAVDENGRTALLFVAGLGSDKCVRLL-AEAGADLD 103 Query: 140 SNHARI 145 R Sbjct: 104 HRDMRG 109 >4OT9-A nrPDB Length = 359 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 7/127 (5%) Query: 16 LATAAARGRVEEVRALLEAGA-----LPNAPNSYGRRPIQVMM-MGSARVAELLLLHGAE 69 LA A G E +RALL++GA L + P+ G P+ + + S +LL+ GAE Sbjct: 160 LALRAGAGAPELLRALLQSGAPAVPQLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAE 219 Query: 70 PNCADPATLTRPVHDAAREGFLDTLVVLH-RAGARLDVRDAWGRLPVDLAEELGHRDVAR 128 + +H A L + L + A ++ R G P+ LA LG+ + R Sbjct: 220 VEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNARTFAGNTPLHLAAGLGYPTLTR 279 Query: 129 YLRAAAG 135 L A Sbjct: 280 LLLKAGA 286 Score = 64.7 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 51/140 (36%), Gaps = 8/140 (5%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMM---MGSARVAELLLLHGA---- 68 L A G+ V LL GA P + +G + + + G+ + LL GA Sbjct: 125 LHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAPELLRALLQSGAPAVP 184 Query: 69 EPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAW-GRLPVDLAEELGHRDVA 127 + PVH A R + L +L +GA ++ + GR + LA E+ + Sbjct: 185 QLLHMPDFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLV 244 Query: 128 RYLRAAAGGTRGSNHARIDA 147 +L + + Sbjct: 245 THLVTKLRANVNARTFAGNT 264 Score = 50.4 bits (119), Expect = 3e-07, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 40/103 (38%), Gaps = 4/103 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS-YGRRPIQVM--MMGSARVAELLLLHGAEPNC 72 + A E + L+++GA A GR + + M V L+ A N Sbjct: 198 VHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHLVTKLRANVNA 257 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPV 115 A T P+H AA G+ +L +AGA + + P+ Sbjct: 258 RTFAGNT-PLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPL 299 Score = 48.9 bits (115), Expect = 8e-07, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 32/89 (35%), Gaps = 6/89 (6%) Query: 40 APNSYGRRPIQVMM-MGSARVAE---LLLLHGAEPNCADPATL--TRPVHDAAREGFLDT 93 A + G P+ + + G V E ++ H + + P+H A G Sbjct: 77 AQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLTNHLHQTPLHLAVITGQTSV 136 Query: 94 LVVLHRAGARLDVRDAWGRLPVDLAEELG 122 + L R GA + D G + LA G Sbjct: 137 VSFLLRVGADPALLDRHGDSAMHLALRAG 165 Score = 37.3 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 20/102 (19%), Positives = 30/102 (29%), Gaps = 9/102 (8%) Query: 54 MGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLV---VLHRAGAR---LDVR 107 G A LL A P+H A G + + +++ Sbjct: 58 YGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQDLGVVNLT 117 Query: 108 DAWGRLPVDLAEELGHRDVAR-YLRAAAGGTRGSNHARIDAA 148 + + P+ LA G V LR A H D+A Sbjct: 118 NHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRH--GDSA 157 Score = 31.1 bits (69), Expect = 0.23, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 16/35 (45%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ 50 L AA G R LL+AGA +A N P+ Sbjct: 266 LHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLP 300 >6EMK-G nrPDB Length = 426 Score = 63.1 bits (152), Expect = 4e-11, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 43/129 (33%), Gaps = 3/129 (2%) Query: 16 LATAAARGRVEEVRALLEAGALPN--APNSYGRRPIQVMMM-GSARVAELLLLHGAEPNC 72 L A+ GR L++ G + G + + +M G + LLL Sbjct: 44 LHYASYHGRYLICVYLIQLGHDKHELIKTFKGNTCVHLALMKGHEQTLHLLLQQFPRFIN 103 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRA 132 P+H A + L +L GA L V D G P+ + E G + L Sbjct: 104 HRGENGRAPIHIACMNDYYQCLSLLIGVGADLWVMDTNGDTPLHVCLEYGSISCMKMLLN 163 Query: 133 AAGGTRGSN 141 + N Sbjct: 164 EGEVSLDDN 172 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 20/108 (18%), Positives = 32/108 (29%), Gaps = 6/108 (5%) Query: 50 QVMMMGSARVAELLLLHGAEP-NCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRD 108 + ++ G+ + + LL + D +H A+ G V L + G Sbjct: 11 EAIIEGNLLIVKRLLRRNPDLLTNIDSENGWSSLHYASYHGRYLICVYLIQLGHDKHELI 70 Query: 109 AW--GRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDI 154 G V LA GH L + R + P I Sbjct: 71 KTFKGNTCVHLALMKGHEQTLHLLLQQFPRFI---NHRGENGRAPIHI 115 >6CV9-A nrPDB Length = 842 Score = 60.8 bits (146), Expect = 3e-10, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 53/168 (31%), Gaps = 35/168 (20%) Query: 4 AAGSSMEPSADWLATAAARGRVEEVRALLE--AGALPNAPNSYGRRPIQVMMMG-SARVA 60 A GS + + AA G + VR +LE N + G+ +Q+ + + Sbjct: 1 AMGSMLSIEEERFLDAAEYGNIPVVRKMLEECHSLNVNCVDYMGQNALQLAVANEHLEIT 60 Query: 61 ELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA------------------ 102 ELLL + + + + A +G++ + + A Sbjct: 61 ELLLKK------ENLSRVGDALLLAISKGYVRIVEAILNHPAFAEGKRLATSPSQSELQQ 114 Query: 103 -RLDVRDAWGR------LPVDLAEELGHRDVA-RYLRAAAGGTRGSNH 142 D G P+ LA ++ LR A R ++ Sbjct: 115 DDFYAYDEDGTRFSHDVTPIILAAHCQEYEIVHTLLRKGARIERPHDY 162 >6DMR-A nrPDB Length = 730 Score = 60.4 bits (145), Expect = 3e-10, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 41/120 (34%), Gaps = 18/120 (15%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSY-----GRRPIQVMMMG-SARVAELLLLHGAE 69 L AA +E L+EA + G+ + + +M + + LL GA Sbjct: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142 Query: 70 PNCADPAT------------LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 + P+ AA G + + +L GA + +D+ G + + Sbjct: 143 VSARATGAAFRRSPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202 Score = 53.9 bits (128), Expect = 3e-08, Method: Composition-based stats. Identities = 35/162 (21%), Positives = 54/162 (33%), Gaps = 33/162 (20%) Query: 1 MEPAAGSSMEPSADW-------LATAAARGRVEEVRALLEAGALPNAPN---SYGRRPIQ 50 ME A + EP+ L A + VRALL GA +A ++ R P Sbjct: 99 MEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGASVSARATGAAFRRSPHN 158 Query: 51 VMMMG-----------SARVAELLLLHGAEPNCADPATLTRPVH-DAAREGFLDTLV--- 95 ++ G S + LL+ HGA+ D T +H + Sbjct: 159 LIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTV-LHILILQPNKTFACQMYN 217 Query: 96 VLHRAGARLDV-------RDAWGRLPVDLAEELGHRDVARYL 130 +L D + G P LA G+ + ++L Sbjct: 218 LLLSYDEHSDHLQSLELVPNHQGLTPFKLAGVEGNTVMFQHL 259 Score = 34.6 bits (78), Expect = 0.020, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 5/60 (8%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDAW-----GRLPVDLAEELGHRDVARYLRAAAGG 136 +H AA L+ +L A L A G+ + +A + ++ R L A Sbjct: 83 LHVAALYDNLEAATLLMEAAPELAKEPALCEPFVGQTALHIAVMNQNLNLVRALLARGAS 142 >6E2G-A nrPDB Length = 727 Score = 58.9 bits (141), Expect = 9e-10, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 42/120 (35%), Gaps = 18/120 (15%) Query: 16 LATAAARGRVEEVRALLE--AGALPNAPNSY---GRRPIQVMMMG-SARVAELLLLHGAE 69 L AA +E L+E + S G+ + + ++ + + LL GA Sbjct: 83 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 142 Query: 70 PNCADPAT------------LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 + + P+ AA G + + +L GA + +D+ G + + Sbjct: 143 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 202 Score = 40.8 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 33/99 (33%), Gaps = 8/99 (8%) Query: 45 GRRPIQVMMM-GSARVAELLLL-HGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA 102 P+ + + + LL G E + T +H AA L+ +VL A Sbjct: 45 WESPLLLAAKENNVQALIKLLKFEGCEVHQKGAMGETA-LHIAALYDNLEAAMVLMEAAP 103 Query: 103 RL-----DVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136 L G+ + +A + ++ R L A Sbjct: 104 ELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 142 >5U0K-A nrPDB Length = 141 Score = 58.5 bits (140), Expect = 1e-09, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 29/88 (32%), Gaps = 3/88 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLH-GAEPNCA 73 L AA G V +R + + R + V G V + L+ P Sbjct: 29 LLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVNPFAK 88 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAG 101 D P+ DA + L+ + +L Sbjct: 89 DRWGNI-PLDDAVQFNHLEVVKLLQDYQ 115 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 49 IQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHR-AGARLDVR 107 + G L + D + T +H AA EG ++ + L + Sbjct: 30 LFAAYSGDVSALRRFALSAMDMEQKDYDSRTA-LHVAAAEGHIEVVKFLIEACKVNPFAK 88 Query: 108 DAWGRLPVDLAEELGHRDVARYLR 131 D WG +P+D A + H +V + L+ Sbjct: 89 DRWGNIPLDDAVQFNHLEVVKLLQ 112 Score = 37.3 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 22/53 (41%) Query: 85 AAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGT 137 AA G + L + ++ +D R + +A GH +V ++L A Sbjct: 32 AAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIEACKVN 84 >3LVQ-E nrPDB Length = 497 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 1/92 (1%) Query: 46 RRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLD 105 ++V S + + ++ +G + T +H AA D L +L + A + Sbjct: 176 HLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTA-LHYAALYNQPDCLKLLLKGRALVG 234 Query: 106 VRDAWGRLPVDLAEELGHRDVARYLRAAAGGT 137 + G +D+A + H++ L A GT Sbjct: 235 TVNEAGETALDIARKKHHKECEELLEQAQAGT 266 Score = 45.4 bits (106), Expect = 9e-06, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 34/92 (36%), Gaps = 5/92 (5%) Query: 16 LATA---AARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPN 71 L A A + + V +++ G +A + G + + +LLL A Sbjct: 175 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 234 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGAR 103 + A T + A ++ + +L +A A Sbjct: 235 TVNEAGETA-LDIARKKHHKECEELLEQAQAG 265 Score = 43.5 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 25/68 (36%), Gaps = 6/68 (8%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADP 75 L AA + + ++ LL+ AL N G + + + E LL A Sbjct: 211 LHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQ------AQA 264 Query: 76 ATLTRPVH 83 T P+H Sbjct: 265 GTFAFPLH 272 >3LJN-A nrPDB Length = 364 Score = 56.6 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 4/87 (4%) Query: 14 DWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPNC 72 + + AA +G+ +EVR L+E G P N +G + G A+ L G Sbjct: 22 EKIHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVG---EV 78 Query: 73 ADPATLTRPVHDAAREGFLDTLVVLHR 99 +P+H A D +V L Sbjct: 79 HSLWHGQKPIHLAVMANKTDLVVALVE 105 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 27/55 (49%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136 +H AAR+G D + L G +++ +G + LA + G D A+YL + Sbjct: 24 IHVAARKGQTDEVRRLIETGVSPTIQNRFGCTALHLACKFGCVDTAKYLASVGEV 78 Score = 40.4 bits (93), Expect = 3e-04, Method: Composition-based stats. Identities = 17/117 (14%), Positives = 41/117 (35%), Gaps = 5/117 (4%) Query: 25 VEEVRALLEAGALPNAPNSYGRRPI-QVMMMGSARVAELLLLHGAEPNCADPA----TLT 79 +E ++ L++ GA P A + P+ + M + +L++ + Sbjct: 153 LEMIKILVQLGASPTAKDKADETPLMRAMEFRNREALDLMMDTVPSKSSLRLDYANKQGN 212 Query: 80 RPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136 +H A + D + G +++ D +P+ L+ + + L Sbjct: 213 SHLHWAILINWEDVAMRFVEMGIDVNMEDNEHTVPLYLSVRAAMVLLTKELLQKTDV 269 >2B0O-E nrPDB Length = 301 Score = 55.0 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 1/92 (1%) Query: 46 RRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLD 105 ++V S + + ++ +G + T +H AA D L +L + A + Sbjct: 195 HLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTA-LHYAALYNQPDCLKLLLKGRALVG 253 Query: 106 VRDAWGRLPVDLAEELGHRDVARYLRAAAGGT 137 + G +D+A + H++ L A GT Sbjct: 254 TVNEAGETALDIARKKHHKECEELLEQAQAGT 285 Score = 43.5 bits (101), Expect = 4e-05, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 34/92 (36%), Gaps = 5/92 (5%) Query: 16 LATA---AARGRVEEVRALLEAGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGAEPN 71 L A A + + V +++ G +A + G + + +LLL A Sbjct: 194 LHLAVKVANQASLPLVDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLKGRALVG 253 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGAR 103 + A T + A ++ + +L +A A Sbjct: 254 TVNEAGETA-LDIARKKHHKECEELLEQAQAG 284 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 25/68 (36%), Gaps = 6/68 (8%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADP 75 L AA + + ++ LL+ AL N G + + + E LL A Sbjct: 230 LHYAALYNQPDCLKLLLKGRALVGTVNEAGETALDIARKKHHKECEELLEQ------AQA 283 Query: 76 ATLTRPVH 83 T P+H Sbjct: 284 GTFAFPLH 291 >2RFA-A nrPDB Length = 232 Score = 55.0 bits (131), Expect = 1e-08, Method: Composition-based stats. Identities = 25/149 (16%), Positives = 48/149 (32%), Gaps = 19/149 (12%) Query: 12 SADWLATAAARGRVEEVRALLE-AGALPNAPNSYGRRPIQ-VMMMGSARVAELLLLHGA- 68 L AA V+ + LL+ G + + G + + + A +L+ Sbjct: 3 WESPLLLAAKENDVQALSKLLKFEGCEVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 62 Query: 69 ---EPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDA-------------WGR 112 EP ++ +H A ++ + L GA + R +G Sbjct: 63 LVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGASVSARATGSVFHYRPHNLIYYGE 122 Query: 113 LPVDLAEELGHRDVARYLRAAAGGTRGSN 141 P+ A +G ++ R L R + Sbjct: 123 HPLSFAACVGSEEIVRLLIEHGADIRAQD 151 Score = 54.3 bits (129), Expect = 2e-08, Method: Composition-based stats. Identities = 21/120 (17%), Positives = 42/120 (35%), Gaps = 18/120 (15%) Query: 16 LATAAARGRVEEVRALLEAGALP-----NAPNSYGRRPIQVMMMG-SARVAELLLLHGAE 69 L AA +E L+EA + G+ + + ++ + + LL GA Sbjct: 41 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVINQNVNLVRALLARGAS 100 Query: 70 PNCADPAT------------LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 + + P+ AA G + + +L GA + +D+ G + + Sbjct: 101 VSARATGSVFHYRPHNLIYYGEHPLSFAACVGSEEIVRLLIEHGADIRAQDSLGNTVLHI 160 >5UQE-A nrPDB Length = 520 Score = 54.3 bits (129), Expect = 2e-08, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 31/84 (36%), Gaps = 2/84 (2%) Query: 49 IQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHR-AGARLDVR 107 + G L + D + T +H AA EG ++ + L + Sbjct: 422 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTA-LHVAAAEGHVEVVKFLLEACKVNPFPK 480 Query: 108 DAWGRLPVDLAEELGHRDVARYLR 131 D W P+D A GH DV + L+ Sbjct: 481 DRWNNTPMDEALHFGHHDVFKILQ 504 Score = 54.3 bits (129), Expect = 2e-08, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 30/94 (31%), Gaps = 3/94 (3%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLH-GAEPNCA 73 L AA G V +R + + R + V G V + LL P Sbjct: 421 LLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPK 480 Query: 74 DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVR 107 D T P+ +A G D +L + + Sbjct: 481 DRWNNT-PMDEALHFGHHDVFKILQEYQVQYTPQ 513 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 22/53 (41%) Query: 85 AAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLRAAAGGT 137 AA G + L + ++ RD R + +A GH +V ++L A Sbjct: 424 AAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVN 476 >6CUD-A nrPDB Length = 806 Score = 53.9 bits (128), Expect = 3e-08, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 47/158 (29%), Gaps = 34/158 (21%) Query: 6 GSSMEPSADWLATAAARGRVEEVRALLEAG--ALPNAPNSYGRRPIQVMMMG-SARVAEL 62 G+S+ + AA G + VR +LE N + G+ +Q+ + V EL Sbjct: 21 GTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTEL 80 Query: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA-------------------R 103 LL + A + + A +G++ + + Sbjct: 81 LLKK------ENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDD 134 Query: 104 LDVRDAWGR------LPVDLAEELGHRDVARYLRAAAG 135 D G P+ LA +V L Sbjct: 135 FYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGA 172 >6OO7-A nrPDB Length = 786 Score = 53.9 bits (128), Expect = 3e-08, Method: Composition-based stats. Identities = 31/144 (21%), Positives = 53/144 (36%), Gaps = 34/144 (23%) Query: 16 LATAAARGRVEEVRALLEAGALPNAP----------NS---YGRRPIQVMM-MGSARVAE 61 L A + ++ V+ L+E GA +A ++ +G P+ + V Sbjct: 166 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 225 Query: 62 LLLLH---GAEPNCADPATLTRPVH-------DAAREGFLDTLVV--LHRAGARL----- 104 LL + A D T +H D+A L + L +AGARL Sbjct: 226 YLLENPHQPASLQAQDSLGNTV-LHALVMIADDSAENSALVVRMYDGLLQAGARLCPNVQ 284 Query: 105 --DVRDAWGRLPVDLAEELGHRDV 126 + + G P+ LA + G ++ Sbjct: 285 LEGIPNLEGLTPLKLAAKEGKIEI 308 Score = 43.1 bits (100), Expect = 5e-05, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 21/105 (20%) Query: 16 LATAAARGRVEEVRALLEAGALP---NAPNSYGRRPIQVMMM-------GSARVAEL--- 62 L+ AA + + V LLE P A +S G + ++M SA V + Sbjct: 212 LSLAACTKQWDVVNYLLENPHQPASLQAQDSLGNTVLHALVMIADDSAENSALVVRMYDG 271 Query: 63 LLLHGA--EPNCA-----DPATLTRPVHDAAREGFLDTLVVLHRA 100 LL GA PN + LT P+ AA+EG ++ + + Sbjct: 272 LLQAGARLCPNVQLEGIPNLEGLT-PLKLAAKEGKIEIFKHILQR 315 Score = 37.3 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 23/62 (37%), Gaps = 13/62 (20%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDA-------------WGRLPVDLAEELGHRDVAR 128 +H A + L + +L GA + + +G LP+ LA DV Sbjct: 166 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 225 Query: 129 YL 130 YL Sbjct: 226 YL 227 >6DJS-A nrPDB Length = 676 Score = 53.1 bits (126), Expect = 5e-08, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 47/158 (29%), Gaps = 34/158 (21%) Query: 6 GSSMEPSADWLATAAARGRVEEVRALLEAG--ALPNAPNSYGRRPIQVMMMG-SARVAEL 62 G+S+ + AA G + VR +LE N + G+ +Q+ + V EL Sbjct: 38 GTSLTAEEERFLDAAEYGNIPVVRKMLEESKTLNVNCVDYMGQNALQLAVGNEHLEVTEL 97 Query: 63 LLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGA-------------------R 103 LL + A + + A +G++ + + Sbjct: 98 LLKK------ENLARIGDALLLAISKGYVRIVEAILNHPGFAASKRLTLSPCEQELQDDD 151 Query: 104 LDVRDAWGR------LPVDLAEELGHRDVARYLRAAAG 135 D G P+ LA +V L Sbjct: 152 FYAYDEDGTRFSPDITPIILAAHCQKYEVVHMLLMKGA 189 >6BOA-A nrPDB Length = 742 Score = 53.1 bits (126), Expect = 5e-08, Method: Composition-based stats. Identities = 20/120 (16%), Positives = 40/120 (33%), Gaps = 18/120 (15%) Query: 16 LATAAARGRVEEVRALLE--AGALPNAPNSY---GRRPIQVMMMG-SARVAELLLLHGAE 69 L AA +E L+E + S G+ + + ++ + + LL A Sbjct: 83 LHIAALYDNLEAAMVLMEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 142 Query: 70 PNCADPAT------------LTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL 117 + T P+ AA + + +L GA + +D+ G + + Sbjct: 143 VSARATGTAFRRSPCNLIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTVLHI 202 Score = 51.6 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 37/162 (22%), Positives = 53/162 (32%), Gaps = 33/162 (20%) Query: 1 MEPAAGSSMEPSADWL-------ATAAARGRVEEVRALLEAGALPNAP---NSYGRRPIQ 50 ME A EP L A + VRALL A +A ++ R P Sbjct: 99 MEAAPELVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRASVSARATGTAFRRSPCN 158 Query: 51 VMMMG-----------SARVAELLLLHGAEPNCADPATLTRPVH-DAAREGFLDTLV--- 95 ++ G S + LL+ HGA+ D T +H + Sbjct: 159 LIYFGEHPLSFAACVNSEEIVRLLIEHGADIRAQDSLGNTV-LHILILQPNKTFACQMYN 217 Query: 96 VLH---RAGARLDVRD----AWGRLPVDLAEELGHRDVARYL 130 +L R G L D G P LA G+ + ++L Sbjct: 218 LLLSYDRHGDHLQPLDLVPNHQGLTPFKLAGVEGNTVMFQHL 259 Score = 36.9 bits (84), Expect = 0.004, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 30/98 (30%), Gaps = 6/98 (6%) Query: 45 GRRPIQVMMM-GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGAR 103 P+ + + LL + A +H AA L+ +VL A Sbjct: 45 WESPLLLAAKDNDVQALNKLLKYEDCKVHQRGAMGETALHIAALYDNLEAAMVLMEAAPE 104 Query: 104 L-----DVRDAWGRLPVDLAEELGHRDVARYLRAAAGG 136 L G+ + +A + ++ R L A Sbjct: 105 LVFEPMTSELYEGQTALHIAVVNQNMNLVRALLARRAS 142 >5U0J-A nrPDB Length = 140 Score = 52.3 bits (124), Expect = 9e-08, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 34/104 (32%), Gaps = 3/104 (2%) Query: 6 GSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLL 64 GS M S L AA G V +R + + R + V G V + LL Sbjct: 18 GSHMVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLL 77 Query: 65 LH-GAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVR 107 P D T P+ +A G D +L + + Sbjct: 78 EACKVNPFPKDRWNNT-PMDEALHFGHHDVFKILQEYQVQYTPQ 120 Score = 51.2 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 33/102 (32%), Gaps = 9/102 (8%) Query: 49 IQVMMMGSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHR-AGARLDVR 107 + G L + D + T +H AA EG ++ + L + Sbjct: 29 LFAAYTGDVSALRRFALSAMDMEQRDYDSRTA-LHVAAAEGHVEVVKFLLEACKVNPFPK 87 Query: 108 DAWGRLPVDLAEELGHRDVARYLRA-------AAGGTRGSNH 142 D W P+D A GH DV + L+ G + Sbjct: 88 DRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKEN 129 >4BSZ-B nrPDB Length = 202 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 25/136 (18%), Positives = 45/136 (33%), Gaps = 18/136 (13%) Query: 14 DWLATAAARGRVEEVR----ALLEAGALPNAPN-SYGRRPIQVMMM-GSARVAELLLL-- 65 D + A G ++ ++ L+ L + + G +L Sbjct: 16 DTIILDARAGDLDSLKDIFTTLVSPELLSTCKESESDSTALHMAAANGHIETVRYILETV 75 Query: 66 ---HGAE-----PNCADPATLTRPVHDAAREGFLDTLVVLH-RAGARLDVRDAWGRLPVD 116 + AE N + T +H A+ G LD + +L A +R+ +G + Sbjct: 76 SRANSAEDLKAFVNEVNKTGNTA-LHWASLNGKLDVVKLLCDEYEADPFIRNKFGHDAIF 134 Query: 117 LAEELGHRDVARYLRA 132 AE G +V Y Sbjct: 135 EAENSGKEEVETYFLK 150 >5AN8-A nrPDB Length = 613 Score = 51.6 bits (122), Expect = 1e-07, Method: Composition-based stats. Identities = 30/144 (20%), Positives = 53/144 (36%), Gaps = 34/144 (23%) Query: 16 LATAAARGRVEEVRALLEAGALPNAP----------NS---YGRRPIQVMM-MGSARVAE 61 L A + ++ V+ L+E GA +A ++ +G P+ + V Sbjct: 91 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 150 Query: 62 LLLLH---GAEPNCADPATLTRPVH------DAAREGFLDTLVV---LHRAGARL----- 104 LL + A D T +H D + E + + L +AGARL Sbjct: 151 YLLENPHPAASLQAQDSLGNTV-LHALVMIADNSPENSALVVRMYDGLLQAGARLCPNVQ 209 Query: 105 --DVRDAWGRLPVDLAEELGHRDV 126 + + G P+ LA + G ++ Sbjct: 210 LEGIPNLEGLTPLKLAAKEGKIEI 233 Score = 43.1 bits (100), Expect = 5e-05, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 43/105 (40%), Gaps = 21/105 (20%) Query: 16 LATAAARGRVEEVRALLEA---GALPNAPNSYGRRPIQVMMM-------GSARVAEL--- 62 L+ AA + + V LLE A A +S G + ++M SA V + Sbjct: 137 LSLAACTKQWDVVNYLLENPHPAASLQAQDSLGNTVLHALVMIADNSPENSALVVRMYDG 196 Query: 63 LLLHGA--EPNCA-----DPATLTRPVHDAAREGFLDTLVVLHRA 100 LL GA PN + LT P+ AA+EG ++ + + Sbjct: 197 LLQAGARLCPNVQLEGIPNLEGLT-PLKLAAKEGKIEIFKHILQR 240 Score = 37.3 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 23/62 (37%), Gaps = 13/62 (20%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDA-------------WGRLPVDLAEELGHRDVAR 128 +H A + L + +L GA + + +G LP+ LA DV Sbjct: 91 LHIAIEKRSLQCVKLLVENGANVHAKACGHFFQKNQDTCFYFGELPLSLAACTKQWDVVN 150 Query: 129 YL 130 YL Sbjct: 151 YL 152 >1DCQ-A nrPDB Length = 278 Score = 50.4 bits (119), Expect = 3e-07, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 46/132 (34%), Gaps = 11/132 (8%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMG----SARVAELLLLHGAEPN 71 L A A G + L G P+ + + + S + + L+ + + Sbjct: 146 LLQAYADGVDLTEKIPLANGHEPD------ETALHLAVRSVDRTSLHIVDFLVQNSGNLD 199 Query: 72 CADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYLR 131 T +H + L +L R A +++ + G P+D+A+ L H L Sbjct: 200 KQTGKGSTA-LHYCCLTDNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLT 258 Query: 132 AAAGGTRGSNHA 143 A G S+ Sbjct: 259 QALSGRFNSHVH 270 >2F37-A nrPDB Length = 251 Score = 47.7 bits (112), Expect = 2e-06, Method: Composition-based stats. Identities = 33/146 (22%), Positives = 54/146 (36%), Gaps = 34/146 (23%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS-------------YGRRPIQVMM-MGSARVAE 61 L A + ++ V+ L+E GA +A +G P+ + V Sbjct: 99 LHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVS 158 Query: 62 LLLLH---GAEPNCADPATLTRPVH-------DAAREGFLDTLVV--LHRAGARL----- 104 LL + A D T +H ++A L T + L +AGARL Sbjct: 159 YLLENPHQPASLQATDSQGNTV-LHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQ 217 Query: 105 --DVRDAWGRLPVDLAEELGHRDVAR 128 D+R+ P+ LA + G ++ R Sbjct: 218 LEDIRNLQDLTPLKLAAKEGKIEIFR 243 Score = 37.7 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 25/77 (32%), Gaps = 16/77 (20%) Query: 70 PNCA---DPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDA-------------WGRL 113 N D +H A + L + +L GA + R +G L Sbjct: 84 VNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGEL 143 Query: 114 PVDLAEELGHRDVARYL 130 P+ LA DV YL Sbjct: 144 PLSLAACTKQWDVVSYL 160 Score = 35.8 bits (81), Expect = 0.007, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 39/104 (37%), Gaps = 19/104 (18%) Query: 16 LATAAARGRVEEVRALLEAGALP---NAPNSYGRRPIQVMMMGSARVAEL---------- 62 L+ AA + + V LLE P A +S G + ++M S AE Sbjct: 145 LSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDG 204 Query: 63 LLLHGA----EPNCADPATLT--RPVHDAAREGFLDTLVVLHRA 100 LL GA D L P+ AA+EG ++ + + Sbjct: 205 LLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQR 248 >6BO5-A nrPDB Length = 695 Score = 46.9 bits (110), Expect = 3e-06, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 50/146 (34%), Gaps = 34/146 (23%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS-------------YGRRPIQVMM-MGSARVAE 61 L A + ++ V+ L+E GA + +G P+ + V Sbjct: 128 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 187 Query: 62 LLLLH---GAEPNCADPATLTRPVH-------DAAREGFLDTLVV--LHRAGARL----- 104 LL + A D T +H ++ L + L + GARL Sbjct: 188 YLLENPHQPASLEATDSLGNTV-LHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 246 Query: 105 --DVRDAWGRLPVDLAEELGHRDVAR 128 ++ + G P+ LA + G ++ R Sbjct: 247 LEEISNHQGLTPLKLAAKEGKIEIFR 272 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 19/104 (18%) Query: 16 LATAAARGRVEEVRALLEAGALP---NAPNSYGRRPIQVMMM-------GSARVAEL--- 62 L+ AA + + V LLE P A +S G + ++M SA V + Sbjct: 174 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 233 Query: 63 LLLHGA--EPNCA----DPATLTRPVHDAAREGFLDTLVVLHRA 100 LL GA P P+ AA+EG ++ + + Sbjct: 234 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 277 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 24/62 (38%), Gaps = 13/62 (20%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDA-------------WGRLPVDLAEELGHRDVAR 128 +H A + L + +L GA + +R +G LP+ LA DV Sbjct: 128 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 187 Query: 129 YL 130 YL Sbjct: 188 YL 189 >5HI9-A nrPDB Length = 770 Score = 46.9 bits (110), Expect = 3e-06, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 50/146 (34%), Gaps = 34/146 (23%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS-------------YGRRPIQVMM-MGSARVAE 61 L A + ++ V+ L+E GA + +G P+ + V Sbjct: 168 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 227 Query: 62 LLLLH---GAEPNCADPATLTRPVH-------DAAREGFLDTLVV--LHRAGARL----- 104 LL + A D T +H ++ L + L + GARL Sbjct: 228 YLLENPHQPASLEATDSLGNTV-LHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 286 Query: 105 --DVRDAWGRLPVDLAEELGHRDVAR 128 ++ + G P+ LA + G ++ R Sbjct: 287 LEEISNHQGLTPLKLAAKEGKIEIFR 312 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 39/104 (37%), Gaps = 19/104 (18%) Query: 16 LATAAARGRVEEVRALLEAGALP---NAPNSYGRRPIQVMMM-------GSARVAEL--- 62 L+ AA + + V LLE P A +S G + ++M SA V + Sbjct: 214 LSLAACTKQWDVVTYLLENPHQPASLEATDSLGNTVLHALVMIADNSPENSALVIHMYDG 273 Query: 63 LLLHGA--EPNCA----DPATLTRPVHDAAREGFLDTLVVLHRA 100 LL GA P P+ AA+EG ++ + + Sbjct: 274 LLQMGARLCPTVQLEEISNHQGLTPLKLAAKEGKIEIFRHILQR 317 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 24/62 (38%), Gaps = 13/62 (20%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDA-------------WGRLPVDLAEELGHRDVAR 128 +H A + L + +L GA + +R +G LP+ LA DV Sbjct: 168 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 227 Query: 129 YL 130 YL Sbjct: 228 YL 229 >5UIL-A nrPDB Length = 405 Score = 45.8 bits (107), Expect = 8e-06, Method: Composition-based stats. Identities = 25/122 (20%), Positives = 49/122 (40%), Gaps = 4/122 (3%) Query: 15 WLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNCA 73 + A + + L+ A ++ N YG P+ V G+ + + L+ GA N Sbjct: 281 EILEACKYSDSKYIAKLIRAKSILFEKNIYGWSPVIVAAYHGNIELIKWLVSKGANINDR 340 Query: 74 DPATLTRPVHDA---AREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 + T ++ + G L +L G L + D D E+ G++++ +Y+ Sbjct: 341 NYKGTTVAMYFKDYMLKSGDYSGLKMLIDLGLDLTLTDYKDYTVFDYLEKSGNKNLLQYM 400 Query: 131 RA 132 A Sbjct: 401 MA 402 >2ETB-A nrPDB Length = 256 Score = 45.4 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 50/146 (34%), Gaps = 34/146 (23%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS-------------YGRRPIQVMM-MGSARVAE 61 L A + ++ V+ L+E GA + +G P+ + V Sbjct: 94 LHIAIEKRSLQCVKLLVENGADVHLRACGRFFQKHQGTCFYFGELPLSLAACTKQWDVVT 153 Query: 62 LLLLH---GAEPNCADPATLTRPVH-------DAAREGFLDTLVV--LHRAGARL----- 104 LL + A D T +H ++ L + L + GARL Sbjct: 154 YLLENPHQPASLEATDSLGNTV-LHALVMIADNSPENSALVIHMYDGLLQMGARLCPTVQ 212 Query: 105 --DVRDAWGRLPVDLAEELGHRDVAR 128 ++ + G P+ LA + G ++ R Sbjct: 213 LEEISNHQGLTPLKLAAKEGKIEIFR 238 >4XD0-A nrPDB Length = 417 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 44/121 (36%), Gaps = 4/121 (3%) Query: 14 DWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM-GSARVAELLLLHGAEPNC 72 D + TA E + LL+ + N G PI + G+ V E L+ G N Sbjct: 293 DEILTACEDKSPEFISKLLKTENILFEKNHLGWSPIIIAAYHGNMDVIEWLVSKGVNIND 352 Query: 73 ADPATLTRPVHDA---AREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARY 129 + T ++ R G L L G L ++D G D + + ++ + Sbjct: 353 RNYKGTTVAMYFKDYMLRSGNYTGLENLINLGLDLFLKDNEGLSVFDYMRKNKNIELFNF 412 Query: 130 L 130 + Sbjct: 413 M 413 >4N5Q-A nrPDB Length = 257 Score = 44.2 bits (103), Expect = 2e-05, Method: Composition-based stats. Identities = 29/179 (16%), Positives = 54/179 (30%), Gaps = 46/179 (25%) Query: 13 ADWLATAAARGRVEEVRALLEA---------GALP--------NAPNSYGRRPIQVMMMG 55 + A + G VEE+R LL+ G A ++ G+ + ++ Sbjct: 4 KKRIFAAVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDT-GKTCLMKALLN 62 Query: 56 ----SARVAELLLLHGAEPNCADPA----------TLTRPVHDAAREGFLDTLVVLHRAG 101 + + +LL E + D ++ A D VL AG Sbjct: 63 INPNTKEIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAG 122 Query: 102 ARLDVRDA--------------WGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARID 146 A ++ +G P+ LA ++ + L S +R + Sbjct: 123 ADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGN 181 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 54/144 (37%), Gaps = 27/144 (18%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R + + L+ AGA NA +G P+ + + Sbjct: 103 LNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIV 162 Query: 61 ELLLLHGAEPNCADPATLTRPVHD--------AAREGFLDTL--VVLHRAG--ARLDVRD 108 +LL+ + + + +H + F+ + ++L R+G +R+ Sbjct: 163 QLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRN 222 Query: 109 AWGRLPVDLAEELGHRDVARYLRA 132 G P+ LA ++G ++ +Y+ + Sbjct: 223 NDGLTPLQLAAKMGKAEILKYILS 246 >6DVZ-A nrPDB Length = 791 Score = 42.7 bits (99), Expect = 6e-05, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 53/173 (30%), Gaps = 46/173 (26%) Query: 19 AAARGRVEEVRALLEA---------GALP--------NAPNSYGRRPIQVMMMG----SA 57 A + G VEE+R LL+ G A ++ G+ + ++ + Sbjct: 126 AVSEGCVEELRELLQDLQDLCRRRRGLDVPDFLMHKLTASDT-GKTCLMKALLNINPNTK 184 Query: 58 RVAELLLLHGAEPNCADPA----------TLTRPVHDAAREGFLDTLVVLHRAGARLDVR 107 + +LL E + D ++ A D VL AGA ++ Sbjct: 185 EIVRILLAFAEENDILDRFINAEYTEEAYEGQTALNIAIERRQGDITAVLIAAGADVNAH 244 Query: 108 DA--------------WGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARID 146 +G P+ LA ++ + L S +R + Sbjct: 245 AKGVFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMENEQTDITSQDSRGN 297 Score = 41.5 bits (96), Expect = 1e-04, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 54/144 (37%), Gaps = 27/144 (18%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R + + L+ AGA NA +G P+ + + Sbjct: 219 LNIAIERRQGDITAVLIAAGADVNAHAKGVFFNPKYQHEGFYFGETPLALAACTNQPEIV 278 Query: 61 ELLLLHGAEPNCADPATLTRPVHD--------AAREGFLDTL--VVLHRAG--ARLDVRD 108 +LL+ + + + +H + F+ + ++L R+G +R+ Sbjct: 279 QLLMENEQTDITSQDSRGNNILHALVTVAEDFKTQNDFVKRMYDMILLRSGNWELETMRN 338 Query: 109 AWGRLPVDLAEELGHRDVARYLRA 132 G P+ LA ++G ++ +Y+ + Sbjct: 339 NDGLTPLQLAAKMGKAEILKYILS 362 Score = 37.7 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 35/102 (34%), Gaps = 21/102 (20%) Query: 16 LATAAARGRVEEVRALLEAG-ALPNAPNSYGRRPIQVMMMGSARVAE------------- 61 LA AA + E V+ L+E + +S G + ++ VAE Sbjct: 266 LALAACTNQPEIVQLLMENEQTDITSQDSRGNNILHALVT----VAEDFKTQNDFVKRMY 321 Query: 62 --LLLLHGA-EPNCADPATLTRPVHDAAREGFLDTLVVLHRA 100 +LL G E P+ AA+ G + L + Sbjct: 322 DMILLRSGNWELETMRNNDGLTPLQLAAKMGKAEILKYILSR 363 >5IRX-A nrPDB Length = 636 Score = 39.6 bits (91), Expect = 5e-04, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 52/153 (33%), Gaps = 43/153 (28%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R + V L+E GA A + +G P+ + + Sbjct: 100 LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIV 159 Query: 61 ELLLLHG---AEPNCADPATLTRPVH---DAAREG----------FLDTLVVLHRAGARL 104 + LL + A+ + D T +H + A + + L++ GA+L Sbjct: 160 KFLLQNSWQPADISARDSVGNTV-LHALVEVADNTVDNTKFVTSMYNEILIL----GAKL 214 Query: 105 -------DVRDAWGRLPVDLAEELGHRDVARYL 130 ++ + G P+ LA G V Y+ Sbjct: 215 HPTLKLEEITNRKGLTPLALAASSGKIGVLAYI 247 Score = 37.7 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 40/105 (38%), Gaps = 21/105 (20%) Query: 16 LATAAARGRVEEVRALLEAG---ALPNAPNSYGRRPIQVMMMGSARVA----------EL 62 L+ AA ++ V+ LL+ A +A +S G + ++ + Sbjct: 147 LSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNE 206 Query: 63 LLLHGAEPN-------CADPATLTRPVHDAAREGFLDTLVVLHRA 100 +L+ GA+ + + LT P+ AA G + L + + Sbjct: 207 ILILGAKLHPTLKLEEITNRKGLT-PLALAASSGKIGVLAYILQR 250 Score = 34.2 bits (77), Expect = 0.022, Method: Composition-based stats. Identities = 26/163 (15%), Positives = 50/163 (30%), Gaps = 37/163 (22%) Query: 4 AAGSSMEPSADWLATAAARGRVEEVRALL-------EAGALPNAPN-SYGRRPIQVMMMG 55 A GS + + A A+ +E+ +LL + + G+ + M+ Sbjct: 1 AMGSRL-YDRRSIFDAVAQSNCQELESLLPFLQRSKKRLTDSEFKDPETGKTCLLKAMLN 59 Query: 56 -----SARVAELL--------LLHGAEPNCADPA-TLTRPVHDAAREGFLDTLVVLHRAG 101 + +A LL L + D +H A + + +L G Sbjct: 60 LHNGQNDTIALLLDVARKTDSLKQFVNASYTDSYYKGQTALHIAIERRNMTLVTLLVENG 119 Query: 102 ARLDVRDA--------------WGRLPVDLAEELGHRDVARYL 130 A + +G LP+ LA + ++L Sbjct: 120 ADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIVKFL 162 >2NYJ-A nrPDB Length = 273 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 29/153 (18%), Positives = 52/153 (33%), Gaps = 43/153 (28%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R + V L+E GA A + +G P+ + + Sbjct: 105 LHIAIERRNMTLVTLLVENGADVQAAANGDFFKKTKGRPGFYFGELPLSLAACTNQLAIV 164 Query: 61 ELLLLHG---AEPNCADPATLTRPVH---DAAREG----------FLDTLVVLHRAGARL 104 + LL + A+ + D T +H + A + + L++ GA+L Sbjct: 165 KFLLQNSWQPADISARDSVGNTV-LHALVEVADNTVDNTKFVTSMYNEILIL----GAKL 219 Query: 105 -------DVRDAWGRLPVDLAEELGHRDVARYL 130 ++ + G P+ LA G V Y+ Sbjct: 220 HPTLKLEEITNRKGLTPLALAASSGKIGVLAYI 252 Score = 37.3 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 40/105 (38%), Gaps = 21/105 (20%) Query: 16 LATAAARGRVEEVRALLEAG---ALPNAPNSYGRRPIQVMMMGSARVA----------EL 62 L+ AA ++ V+ LL+ A +A +S G + ++ + Sbjct: 152 LSLAACTNQLAIVKFLLQNSWQPADISARDSVGNTVLHALVEVADNTVDNTKFVTSMYNE 211 Query: 63 LLLHGAEPN-------CADPATLTRPVHDAAREGFLDTLVVLHRA 100 +L+ GA+ + + LT P+ AA G + L + + Sbjct: 212 ILILGAKLHPTLKLEEITNRKGLT-PLALAASSGKIGVLAYILQR 255 >6C8G-A nrPDB Length = 675 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 27/92 (29%), Gaps = 21/92 (22%) Query: 44 YGRRPIQVM---MMGSARVAELLLLHGAEPNCA---------DPAT----LTRPVHDAAR 87 G+ + + ELL+ GA+ + D P+ AA Sbjct: 102 RGQTALHIAIERRCKHY--VELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 159 Query: 88 EGFLDTLVVLHRAG---ARLDVRDAWGRLPVD 116 D + L A + +D+ G + Sbjct: 160 TNQPDIVHYLTENAHKKADIRRQDSRGNTVLH 191 Score = 36.9 bits (84), Expect = 0.003, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 25/86 (29%), Gaps = 19/86 (22%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R V L+E GA +A +G P+ + + Sbjct: 107 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 166 Query: 61 ELLLLHG---AEPNCADPATLTRPVH 83 L + A+ D T +H Sbjct: 167 HYLTENAHKKADIRRQDSRGNTV-LH 191 Score = 33.1 bits (74), Expect = 0.047, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 25/82 (30%), Gaps = 16/82 (19%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDA--------------WGRLPVDLAEELGHRDVA 127 +H A + +L GA + + +G LP+ LA D+ Sbjct: 107 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 166 Query: 128 RYLR--AAAGGTRGSNHARIDA 147 YL A +R + Sbjct: 167 HYLTENAHKKADIRRQDSRGNT 188 >6BBJ-A nrPDB Length = 868 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 15/92 (16%), Positives = 27/92 (29%), Gaps = 21/92 (22%) Query: 44 YGRRPIQVM---MMGSARVAELLLLHGAEPNCA---------DPAT----LTRPVHDAAR 87 G+ + + ELL+ GA+ + D P+ AA Sbjct: 233 RGQTALHIAIERRCKHY--VELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAAC 290 Query: 88 EGFLDTLVVLHRAG---ARLDVRDAWGRLPVD 116 D + L A + +D+ G + Sbjct: 291 TNQPDIVHYLTENAHKKADIRRQDSRGNTVLH 322 Score = 36.9 bits (84), Expect = 0.003, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 25/86 (29%), Gaps = 19/86 (22%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R V L+E GA +A +G P+ + + Sbjct: 238 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 297 Query: 61 ELLLLHG---AEPNCADPATLTRPVH 83 L + A+ D T +H Sbjct: 298 HYLTENAHKKADIRRQDSRGNTV-LH 322 Score = 33.1 bits (74), Expect = 0.047, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 25/82 (30%), Gaps = 16/82 (19%) Query: 82 VHDAAREGFLDTLVVLHRAGARLDVRDA--------------WGRLPVDLAEELGHRDVA 127 +H A + +L GA + + +G LP+ LA D+ Sbjct: 238 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPDIV 297 Query: 128 RYLR--AAAGGTRGSNHARIDA 147 YL A +R + Sbjct: 298 HYLTENAHKKADIRRQDSRGNT 319 >6MHW-A nrPDB Length = 826 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 35/102 (34%), Gaps = 21/102 (20%) Query: 16 LATAAARGRVEEVRALLEAG-ALPNAPNSYGRRPIQVMMMGSARVAE------------- 61 LA AA + E V+ L+E + +S G + ++ VAE Sbjct: 267 LALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVT----VAEDFKTQNDFVKRMY 322 Query: 62 --LLLLHGA-EPNCADPATLTRPVHDAAREGFLDTLVVLHRA 100 +LL G E P+ AA+ G + L + Sbjct: 323 DMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSR 364 Score = 29.6 bits (65), Expect = 0.61, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 14/37 (37%) Query: 110 WGRLPVDLAEELGHRDVARYLRAAAGGTRGSNHARID 146 +G P+ LA ++ + L S +R + Sbjct: 262 FGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGN 298 >3W9G-A nrPDB Length = 260 Score = 38.5 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 25/141 (17%), Positives = 42/141 (29%), Gaps = 35/141 (24%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R V L+E GA +A +G P+ + + Sbjct: 97 LHIAIERRCKHYVELLVEKGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIV 156 Query: 61 ELLLLHG---AEPNCADPATLTRPVH------DAAREGFLDTLV----VLHRAGA---RL 104 L +G A+ D T +H D RE +L + Sbjct: 157 HYLTENGHKQADLRRQDSRGNTV-LHALVAIADNTRENTKFVTKMYDLLLIKCAKLFPDT 215 Query: 105 DVR---DAWGRLPVDLAEELG 122 ++ + G P+ +A + G Sbjct: 216 NLEALLNNDGLSPLMMAAKTG 236 >4DX2-A nrPDB Length = 259 Score = 34.6 bits (78), Expect = 0.020, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 40/141 (28%), Gaps = 35/141 (24%) Query: 16 LATAAARGRVEEVRALLEAGALPNAPNS--------------YGRRPIQVMM-MGSARVA 60 L A R V L+ GA +A +G P+ + + Sbjct: 95 LHIAIERRCKHYVELLVAQGADVHAQARGRFFQPKDEGGYFYFGELPLSLAACTNQPHIV 154 Query: 61 ELLLLH---GAEPNCADPATLTRPVH------DAAREGFLDTLV----VLHRAG---ARL 104 L + A+ D T +H D RE +L + Sbjct: 155 NYLTENPHKKADMRRQDSRGNTV-LHALVAIADNTRENTKFVTKMYDLLLLKCARLFPDS 213 Query: 105 DVR---DAWGRLPVDLAEELG 122 ++ + G P+ +A + G Sbjct: 214 NLEAVLNNDGLSPLMMAAKTG 234 >6ED3-A nrPDB Length = 848 Score = 30.4 bits (67), Expect = 0.32, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 45/142 (31%), Gaps = 22/142 (15%) Query: 4 AAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELL 63 A G+S +P + AA + + L + + G + VA+LL Sbjct: 74 ATGASTQPQLSRESLAA----ITTAQQLATELDDEYVSTEHVMVGL---ATGDSDVAKLL 126 Query: 64 LLHGAEPNC--------ADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPV 115 HGA P A +T P +A T L + L R G+L Sbjct: 127 TGHGASPQALREAFVKVRGSARVTSPEPEA-------TYQALQKYSTDLTARAREGKLDP 179 Query: 116 DLAEELGHRDVARYLRAAAGGT 137 + + R V + L Sbjct: 180 VIGRDNEIRRVVQVLSRRTKNN 201 >6G1K-A nrPDB Length = 921 Score = 29.2 bits (64), Expect = 0.72, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 31/94 (32%), Gaps = 20/94 (21%) Query: 11 PSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMMGSARVAELLLLHGAEP 70 D L A + V V LL ++P G +V +LL + Sbjct: 95 YVGDALLHAIRKEVVGAVELLLNH-----------KKP-----SGEKQVPPILL----DK 134 Query: 71 NCADPATLTRPVHDAAREGFLDTLVVLHRAGARL 104 +D P+ AA + + +L + G + Sbjct: 135 QFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSV 168 >6EC3-A nrPDB Length = 471 Score = 27.7 bits (60), Expect = 2.4, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 28/66 (42%), Gaps = 4/66 (6%) Query: 23 GRVEEV--RALLEAGAL-PNAPNSYGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLT 79 G +E V LL P + R P+ +G V ++ L+HG+ PN +D T Sbjct: 396 GCLEGVPGSHLLPDDIDVPEIRDGGPRVPVP-SKVGDVIVHDVRLVHGSGPNPSDQWRRT 454 Query: 80 RPVHDA 85 + A Sbjct: 455 IVIEFA 460 >2H12-A nrPDB Length = 436 Score = 26.1 bits (56), Expect = 6.1, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 15/39 (38%) Query: 44 YGRRPIQVMMMGSARVAELLLLHGAEPNCADPATLTRPV 82 G Q+ S LLL+G PN A T T + Sbjct: 77 RGYPIAQLAENASYEEVIYLLLNGELPNKAQYDTFTNTL 115 >5XE7-A nrPDB Length = 312 Score = 26.1 bits (56), Expect = 6.2, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 2/51 (3%) Query: 15 WLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQV-MMMGSARVAELLL 64 L A A G ++ V +LL +S G+ P V + GS +V +L Sbjct: 183 RLMAAMAAGDLDTVVSLLHPDVTFTG-DSNGKAPTAVRAVRGSDKVVRFIL 232 >3NA5-A nrPDB Length = 570 Score = 25.7 bits (55), Expect = 7.6, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 14/32 (43%) Query: 83 HDAAREGFLDTLVVLHRAGARLDVRDAWGRLP 114 H + F+ L VL G + V++ G P Sbjct: 112 HALSEPAFISVLEVLAANGVDVIVQENNGFTP 143 >3B8B-A nrPDB Length = 292 Score = 25.7 bits (55), Expect = 9.3, Method: Composition-based stats. Identities = 8/47 (17%), Positives = 17/47 (36%) Query: 84 DAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLAEELGHRDVARYL 130 DAA + L + + ++ P+ +A+ H + L Sbjct: 29 DAALKAGEKILSIYEDPKSDFEIERKADNSPLTIADRKAHEAIVAIL 75 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.139 0.374 Lambda K H 0.267 0.0424 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 5,957,248 Number of Sequences: 36641 Number of extensions: 217403 Number of successful extensions: 1354 Number of sequences better than 10.0: 82 Number of HSP's better than 10.0 without gapping: 108 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 557 Number of HSP's gapped (non-prelim): 352 length of query: 156 length of database: 10,336,785 effective HSP length: 89 effective length of query: 67 effective length of database: 7,075,736 effective search space: 474074312 effective search space used: 474074312 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 55 (25.7 bits)