BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P42765 (397 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4C2K-A nrPDB 815 0.0 4E1L-A nrPDB 357 4e-99 4N44-A nrPDB 355 2e-98 3SS6-A nrPDB 351 3e-97 4DD5-A nrPDB 346 1e-95 4NZS-A nrPDB 343 1e-94 1NL7-A nrPDB 313 6e-86 4O9A-A nrPDB 308 2e-84 1ULQ-A nrPDB 306 1e-83 4WYS-A nrPDB 303 6e-83 1WL4-A nrPDB 298 2e-81 5LP7-H nrPDB 293 1e-79 5CBQ-A nrPDB 286 1e-77 6BN2-A nrPDB 268 3e-72 2IBU-A nrPDB 261 4e-70 3GOA-A nrPDB 256 2e-68 2WUA-A nrPDB 253 9e-68 6ARG-A nrPDB 250 7e-67 2C7Y-A nrPDB 249 2e-66 1WDK-C nrPDB 241 3e-64 5XYJ-B nrPDB 239 2e-63 2IIK-A nrPDB 234 7e-62 3SVK-A nrPDB 231 3e-61 6BJA-A nrPDB 229 2e-60 6BJB-A nrPDB 221 4e-58 4B3J-C nrPDB 219 1e-57 1PXT-A nrPDB 209 2e-54 5ZQZ-B nrPDB 201 4e-52 4UBW-A nrPDB 187 8e-48 6ESQ-A nrPDB 49 3e-06 6HRV-A nrPDB 45 6e-05 5M3K-C nrPDB 44 9e-05 4BI9-A nrPDB 43 3e-04 4YZO-A nrPDB 39 0.004 4QAV-A nrPDB 37 0.011 2IX4-A nrPDB 37 0.021 5LNQ-A nrPDB 36 0.036 2GP6-A nrPDB 34 0.094 5W2O-A nrPDB 33 0.15 1J3N-A nrPDB 33 0.23 3E60-A nrPDB 32 0.34 4R8E-A nrPDB 32 0.44 6QSP-A nrPDB 32 0.70 3O04-A nrPDB 31 0.73 6GC1-A nrPDB 31 0.87 1OXH-A nrPDB 31 1.00 4JPF-A nrPDB 30 2.1 2GQD-A nrPDB 30 2.2 1PWH-A nrPDB 29 2.8 4JRH-A nrPDB 29 3.0 3LM6-A nrPDB 29 3.4 5BY7-A nrPDB 29 4.1 2IWZ-A nrPDB 28 8.5 >4C2K-A nrPDB Length = 417 Score = 815 bits (2104), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/397 (100%), Positives = 397/397 (100%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL Sbjct: 21 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 80 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE Sbjct: 81 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 140 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD Sbjct: 141 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 200 Query: 181 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 240 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK Sbjct: 201 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 260 Query: 241 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 300 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI Sbjct: 261 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 320 Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 360 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR Sbjct: 321 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 380 Query: 361 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA 397 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA Sbjct: 381 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA 417 >4E1L-A nrPDB Length = 395 Score = 357 bits (917), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 179/391 (45%), Positives = 256/391 (65%), Gaps = 2/391 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 ++ V +V+A RTP G++GG+ K+ +A L A K A+S ++ +D VI+GNVLQ+ Sbjct: 4 MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQTG 63 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 +AR + + GIP P+ T+N+LCGSG +S+ Q I E +VV+ GGTE+MS Sbjct: 64 LGQ-NVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENMS 122 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 QAPY V RFG+K+G+ ++ L L D Q M +TAEN+A K + +RE DK A Sbjct: 123 QAPYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKLA 182 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGK-QTMQVDEHARPQTTLEQLQKLPPVFKKD 242 L+SQ + + A F +E+ P++V ++GK +T+ DE+ + T E L KL P FKKD Sbjct: 183 LESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPAFKKD 242 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 GTVTAGNASG+ DGA +I+ S+ + PLA+I Y +G +P +MG GP+PA Sbjct: 243 GTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPIPATRK 302 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 ALKKAGLS+ D+DL+E NEAFA Q LAV+ L +D SK NVNGGAIALGHP+G SG+RI Sbjct: 303 ALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGASGARIL 362 Query: 363 AHLVHELRRRGGKYAVGSACIGGGQGIAVII 393 L++E+++R + + + CIGGGQGI++++ Sbjct: 363 VTLIYEMQKRKVETGLATLCIGGGQGISMVV 393 >4N44-A nrPDB Length = 400 Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 180/395 (45%), Positives = 256/395 (64%), Gaps = 9/395 (2%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 ++ V + +A RT G+YG LKD A DL A K A+ + PE V+ VI+GNVLQ+ Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 AR + G+P E PA+TIN++CGSG +++ Q I +A+V++ GG E+MS Sbjct: 61 LGQ-NPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMS 119 Query: 124 QAPYCVRNVRFGTKLGS----DIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 +APY N R+G ++G+ D + D LW + D H M +TAEN+A + ISREE Sbjct: 120 RAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYH----MGITAENIAERWNISREEQ 175 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF 239 D++AL SQ++ + A +G F DE+ P+ +K +KG+ + DEH R +T+E L KL P F Sbjct: 176 DEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAF 235 Query: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 KKDGTVTAGNASG+ D A ++I S + K+ PLA+IV Y +G DP+IMG GP A Sbjct: 236 KKDGTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYA 295 Query: 300 ISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 A++KAG ++ ++DL+E NEAFA Q LAV + L D++K NVNGGAIALGHP+G SG+ Sbjct: 296 TKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGA 355 Query: 360 RITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 RI LVH +++R K + + CIGGGQG A++++ Sbjct: 356 RILVTLVHAMQKRDAKKGLATLCIGGGQGTAILLE 390 >3SS6-A nrPDB Length = 394 Score = 351 bits (901), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 175/392 (44%), Positives = 251/392 (64%), Gaps = 2/392 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 + V + AA R+P G +GG LK+ T +L+ + A+ G V P VD VI+G+ +Q + Sbjct: 4 MHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQRT 63 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 +A AR L G P TI R C SG Q+I++ +I + +EVV+ GG E+MS Sbjct: 64 DEA-NTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAMS 122 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 +PY ++ R+G +L ++ D++W L D + M TAENL +++I+REE D+ A Sbjct: 123 SSPYALKQHRWGQRLQHG-EIRDTVWEVLEDPIHHIMMGETAENLVEQYEITREEQDEVA 181 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 L+S A ++GYF+D++ PI +K ++ + DEH R T E+L L P F+KDG Sbjct: 182 LRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKDG 241 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 +VTAGNASG+ DG+ +++ SE+ K+ PLARIVGY V+G DP IMGIGP PAI Sbjct: 242 SVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRKG 301 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 L+K SL+D DL+E+NEAFA QYLAVE+ LDLD K NVNG + LGHP+G +G+RIT Sbjct: 302 LEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTGARITV 361 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQS 395 L+HEL+RRG + + S C+GGG G+A+ I++ Sbjct: 362 SLIHELKRRGLEKGIASLCVGGGIGVALFIEA 393 >4DD5-A nrPDB Length = 396 Score = 346 bits (888), Expect = 1e-95, Method: Compositional matrix adjust. Identities = 169/391 (43%), Positives = 257/391 (65%), Gaps = 1/391 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R V + +A RT G++GG K +A +L AAK A+ ++P+ +D ++G VL ++ Sbjct: 6 MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVL-TA 64 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 +AR + L GIP E PA+TIN +CGSG +S+ Q I + +A+++L GG E+MS Sbjct: 65 GLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMS 124 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 +PY V + R+G ++G ++ + L+D M +TAEN+A + I+REE D+ A Sbjct: 125 MSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELA 184 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 L SQ + + A G F++E+ P+ +K +KG + DE+ +P TT+E+L KL P FKKDG Sbjct: 185 LASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGTTMEKLAKLRPAFKKDG 244 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 TVTAGNASG+ DGA +++ +++ ++ PLA IV Y +G DP IMG GPVPA A Sbjct: 245 TVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVPATKKA 304 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 L+ A ++++D+DLVE NEAFA Q +AV R L++D++K NVNGGAIA+GHP+G SG+RI Sbjct: 305 LEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSGARILT 364 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 L++E++RR K + + CIGGG G +I++ Sbjct: 365 TLLYEMKRRDAKTGLATLCIGGGMGTTLIVK 395 >4NZS-A nrPDB Length = 399 Score = 343 bits (879), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 178/391 (45%), Positives = 248/391 (63%), Gaps = 2/391 (0%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 R V VV+ RT G +GG LKD +L + AL+ +VS + V V+ GNV+Q+ Sbjct: 8 REVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEP 67 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 +YL R + G+ PALT+NRLCGSG Q+IV+ Q I + + +V + GG ESMS+ Sbjct: 68 RDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSR 127 Query: 125 APYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 APY R+G ++G D L D + +L D ++ M +TAEN+A ++ ISR + D+ AL Sbjct: 128 APYLAPAARWGARMG-DAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQDEAAL 186 Query: 185 QSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF-KKDG 243 +S +R AA AGYF D++ P+ K +KG T DEH R T++ + KL PVF K++G Sbjct: 187 ESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMTKLRPVFVKENG 246 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 TVTAGNASG+ D A AV++ ++ PLAR+V Y +G DP MGIGPVPA A Sbjct: 247 TVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPATKIA 306 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 L++AGL + D+D++E NEAFA Q AV ++L LD +K N NG I+LGHP+G +G+ IT Sbjct: 307 LERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGALITV 366 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 +HEL R G+YA+ + CIGGGQGIA I + Sbjct: 367 KALHELNRVQGRYALVTMCIGGGQGIAAIFE 397 >1NL7-A nrPDB Length = 392 Score = 313 bits (803), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 166/390 (42%), Positives = 239/390 (61%), Gaps = 4/390 (1%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 + + +A RT G++ G + A +L A L V+ V+ VI+G VL + + Sbjct: 5 IVIASAARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVL-PAGEG 63 Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 AR ++ G+P+E A +N+LCGSG +++ G Q+I +A +++ GG ESMS AP Sbjct: 64 QNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAP 123 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 +C ++R G K+G D K+ D++ LTD M TAEN+A + ++SR+E D +A+ Sbjct: 124 HCA-HLRGGVKMG-DFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAVA 181 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTV 245 SQ + +AA G F DE+ P VK +KG T+ DE+ R TL+ + KL P F K+GTV Sbjct: 182 SQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKEGTV 241 Query: 246 TAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALK 305 TAGNASG+ DGA A ++ SE + PL RIV + G DP +MG GP+PA AL+ Sbjct: 242 TAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRKALE 301 Query: 306 KAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHL 365 +AG + D+DLVE NEAFA Q AV + L D S NVNGGAIA+GHP+G SG+RI L Sbjct: 302 RAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARILNTL 361 Query: 366 VHELRRRGGKYAVGSACIGGGQGIAVIIQS 395 + E++RRG + + + CIGGG G+A+ I+S Sbjct: 362 LFEMKRRGARKGLATLCIGGGMGVAMCIES 391 >4O9A-A nrPDB Length = 398 Score = 308 bits (790), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 172/390 (44%), Positives = 242/390 (62%), Gaps = 4/390 (1%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 V +V+A RT G +GG L A +L KAAL V PE V VIMG VL + S Sbjct: 9 VVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGSGQ 68 Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 AR ++ G+P PA+TIN++ GSG ++++ I +AE+V+ GG E+MS AP Sbjct: 69 -NPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAAP 127 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 + + R G ++G D KL D++ V L D + Q M +TAEN+A ++ I+RE D++A+ Sbjct: 128 HVLPGSRDGFRMG-DAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVG 186 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKTKKGKQT-MQVDEHARPQTTLEQLQKLPPVFKKDGT 244 SQ + +AA AG F++E+ P+ + +KG + DE R TL+ + L P F K GT Sbjct: 187 SQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAGT 246 Query: 245 VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGAL 304 VTA NASG+ DGA AV++ S K+ TPLA I Y +G DP +MG+GPVPA AL Sbjct: 247 VTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRAL 306 Query: 305 KKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAH 364 +A + +D+DL+E+NEAFA Q LAV + + D SK NVNGGAIA+GHP+G SG RI Sbjct: 307 SRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVT 366 Query: 365 LVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 L+HE++RR K + S CIGGG G+A+ ++ Sbjct: 367 LLHEMKRRDAKKGLASLCIGGGMGVALAVE 396 >1ULQ-A nrPDB Length = 401 Score = 306 bits (783), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 172/394 (43%), Positives = 231/394 (58%), Gaps = 7/394 (1%) Query: 8 FVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAI 67 ++V A RTP G +GG L DL A + V E V+ V G Q+ D Sbjct: 5 WIVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAGEDNR 64 Query: 68 YLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPY 127 +AR L G P E T+NRLCGSG +++ + I E +V + G ESMS+APY Sbjct: 65 NVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMSRAPY 124 Query: 128 CVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQL-----PMAMTAENLAVKHKISREECDKY 182 V G G+ + + +L + +Q M TAENLA + I REE D++ Sbjct: 125 AVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRREEQDRF 184 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 242 AL S Q+ A + G F DE+ P+ VK K + ++ DE R T+LE+L L PVF++ Sbjct: 185 ALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDTSLEKLAALRPVFREG 244 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 GTVTAGN+S + DGA AV++ S+D K H PLAR+ V+G P IMGIGPVPA Sbjct: 245 GTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGIGPVPATRK 304 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAV--ERSLDLDISKTNVNGGAIALGHPLGGSGSR 360 AL++AGLS D+ L+E+NEAFA Q LAV E SL ++ + N NGGAIALGHPLG SG+R Sbjct: 305 ALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGHPLGASGAR 364 Query: 361 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 I LVHE+RRR ++ + + CIG GQGIAV+++ Sbjct: 365 ILTTLVHEMRRRKVQFGLATMCIGVGQGIAVVVE 398 >4WYS-A nrPDB Length = 405 Score = 303 bits (777), Expect = 6e-83, Method: Compositional matrix adjust. Identities = 173/399 (43%), Positives = 238/399 (59%), Gaps = 10/399 (2%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 M ++ +V+A RT G++ G L +A DL KAA+ K+ + VD VIMGNVL Sbjct: 1 MGAMKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVL 60 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 Q+ AR L+ G+ + T+N++CGSG +S+ Q I +A+ ++ GG E Sbjct: 61 QAGLGQ-NPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGME 119 Query: 121 SMSQAPYCV-RNVRFGTKLGS----DIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKIS 175 +MS APY + R G +LG D+ L D L + H M +TAEN+A ++ I+ Sbjct: 120 NMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYH----MGITAENVAKEYGIT 175 Query: 176 REECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKL 235 RE D+ AL SQ++ AA ++G F E+ P+ V T+K DE + +T E L L Sbjct: 176 REMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGAL 235 Query: 236 PPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIG 295 P F K GTVTAGNASG+ DGA A++I E A TPLARI Y G P++MG+G Sbjct: 236 RPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMG 295 Query: 296 PVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLG 355 PVPA AL+ AGL L D+DL+E NEAFA Q+LAV ++L D K NVNGGAIALGHP+G Sbjct: 296 PVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIG 355 Query: 356 GSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 SG+RI L+H ++ R + + CIGGGQGIA++I+ Sbjct: 356 ASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIE 394 >1WL4-A nrPDB Length = 397 Score = 298 bits (763), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 168/391 (42%), Positives = 232/391 (59%), Gaps = 6/391 (1%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 V +V+A RT G++ G L DL K L V+PE V VI G+VL + Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQ 67 Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 R + GIP PA + +CGSG +++ Q I + ++ +V+ GG E+MS+AP Sbjct: 68 -NPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP 126 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 + + +R G K+G ++ L DS+ LTD M +TAEN+A K ++SRE+ DK A+ Sbjct: 127 H-LAYLRTGVKIG-EMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVL 184 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGT- 244 SQ R + A AG+F+ E+ P+ V T+KG ++ DE R + +E + KL P F DGT Sbjct: 185 SQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTG 244 Query: 245 -VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 VT NASG+ DGA AV++ + K TPLARIV + G +PSIMGIGP+PAI A Sbjct: 245 TVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQA 304 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 + KAG SL+D+D+ E+NEAFA A+ + L L+ K N+ GGAIALGHPLG SG RI Sbjct: 305 VTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILV 364 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 L+H L R G V + CIGGG GIA+ +Q Sbjct: 365 TLLHTLERMGRSRGVAALCIGGGMGIAMCVQ 395 >5LP7-H nrPDB Length = 393 Score = 293 bits (750), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 163/396 (41%), Positives = 236/396 (59%), Gaps = 10/396 (2%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R +V+A RTPFG +GG+LK+ A +L K AL VS + V+ +MG V+Q+ Sbjct: 1 MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAG 60 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 S I +R G+P P+ T+N++C SG +++ Q I ++A++++ GG ESMS Sbjct: 61 SGQIP-SRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMS 119 Query: 124 QAPYCVRNVRFGTKLGS----DIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 PY V R+G ++G D+ + D L + + H MA+ A ++ ISR E Sbjct: 120 NIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVH----MAVHGNTAAKEYAISRREQ 175 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGK-QTMQVDEHARPQTTLEQLQKLPPV 238 D++AL+S R A D G F DE+ P+ +KGK + DE R T+L+QL KL P+ Sbjct: 176 DEWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDTSLDQLAKLAPI 235 Query: 239 FKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 298 + DG++TAGNA GV DGAGA ++ SE+ + PLA I+G+ +G + P Sbjct: 236 YASDGSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGF 295 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 AI+ LKK GL+++D+DL EVNEAFA L E+ + D+ K NVNGGAIALGHP+G SG Sbjct: 296 AINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASG 355 Query: 359 SRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 +RI LV+EL+RRGG V + C G QG AV++Q Sbjct: 356 ARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQ 391 >5CBQ-A nrPDB Length = 413 Score = 286 bits (732), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 159/402 (39%), Positives = 233/402 (57%), Gaps = 13/402 (3%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R + RTP G YGG+ + TA DL A K L ++ + V+ VI+G+ + Sbjct: 9 MRDAVICEPVRTPIGRYGGMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCY-PN 67 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 S+A + R V L G+P P + ++R CGSG Q+++ C ++ + ++V+ GG ESMS Sbjct: 68 SEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESMS 127 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTD-----QHVQLPMAMTAENLAVKHKISREE 178 + ++R+G + +++ D L T V M TAENL ++ ISR E Sbjct: 128 NVAFYSTDMRWGGAR-TGVQIHDGLARGRTTAGGKFHPVPGGMLETAENLRREYHISRTE 186 Query: 179 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV 238 D+ A++S QR AA G +E+ P+ V+T+ G++T+ VDEH R TT+E L KL PV Sbjct: 187 QDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHPRADTTVEALAKLKPV 246 Query: 239 FKK---DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIG 295 K + TVTAGN+SG D A I+ + + + PL R+V + +G P +MGIG Sbjct: 247 LLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPDLMGIG 306 Query: 296 PVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSL---DLDISKTNVNGGAIALGH 352 PVPA AL KAGL+L D+DL+E+NEAFA Q LAV R + D +TNV G I+LGH Sbjct: 307 PVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSGISLGH 366 Query: 353 PLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 P+G +G R+ A L EL RR +Y + + CIGGGQG+A + + Sbjct: 367 PVGATGGRMLATLARELHRREARYGLETMCIGGGQGLAAVFE 408 >6BN2-A nrPDB Length = 401 Score = 268 bits (685), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 151/394 (38%), Positives = 228/394 (57%), Gaps = 5/394 (1%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 ++ VF+V+A RTP G++ G L AT L A K AL ++P + V MGNVLQ+ Sbjct: 9 MKEVFIVSAVRTPMGSFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDVYMGNVLQAG 68 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + A+ L G+P TP +N++C SG ++++ Q + + E ++ GG E+MS Sbjct: 69 -EGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMS 127 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKY 182 Q P+ + R G KLG DIKL+D L LTD + + M AE A ++ I+REE D + Sbjct: 128 QVPHYIDG-RNGVKLG-DIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNITREEQDAF 185 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKK- 241 A+QS +R A G F +E+ P+ + +KG+ + ++ +++ LP VF+K Sbjct: 186 AIQSYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNVKFDRIPTLPTVFQKE 245 Query: 242 DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAIS 301 +GTVTA NAS + DGA A+++ S++ ++ PLA+IV Y + P P A+ Sbjct: 246 NGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEWFTTAPAKALP 305 Query: 302 GALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRI 361 AL KA L++ D+D E NEAF+ LA + L LD +K NVNGGA+ALGHPLG SGSRI Sbjct: 306 IALAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALGHPLGSSGSRI 365 Query: 362 TAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQS 395 L++ L++ KY + C GGG A++I++ Sbjct: 366 IVTLINVLKQNNAKYGAAAICNGGGGASAIVIEN 399 >2IBU-A nrPDB Length = 395 Score = 261 bits (667), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 158/393 (40%), Positives = 224/393 (56%), Gaps = 8/393 (2%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 L+ V +V+A RTP G++ G L AT L A + A+ + E V MGNVLQ Sbjct: 7 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 66 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + R L G+P TP TIN++C SG ++I+ Q + +V++ GG ESMS Sbjct: 67 -EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 125 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVS-LTDQHVQLPMAMTAENLAVKHKISREECDKY 182 PY + R T G +KLED + LTD + ++ M AEN A K I+R E D Y Sbjct: 126 NVPYVMN--RGSTPYGG-VKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 182 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 242 A+ S R KAA +AG F +E+ P+ V K + ++ + ++ KL VF+K+ Sbjct: 183 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKE 242 Query: 243 -GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAIS 301 GTVTA NAS + DGA A+++ + DA K+ N TPLARIV + + +P I PV A S Sbjct: 243 NGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAAS 302 Query: 302 GALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRI 361 LK GL +D+ + EVNEAF+ LA + L++D K N+NGGA++LGHP+G SG+RI Sbjct: 303 MVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARI 362 Query: 362 TAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 HL H L++ G+Y + S C GGG A++IQ Sbjct: 363 VGHLTHALKQ--GEYGLASICNGGGGASAMLIQ 393 >3GOA-A nrPDB Length = 387 Score = 256 bits (653), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 157/395 (39%), Positives = 217/395 (54%), Gaps = 20/395 (5%) Query: 7 VFVVAAKRTPFG-AYGGLLKDFTATDLSEFAAKAALSAG-KVSPETVDSVIMGNVLQSSS 64 V +V A RTP G + GG ++ A DLS ++ L+ ++ T+D + G V Q+ Sbjct: 4 VVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQTLE 63 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 +AR+ L IP PA+T+NRLCGS Q++ + + I +A+V L GG E M Sbjct: 64 QGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEHMGH 123 Query: 125 APYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 P V F L ++ + M +TAE L+ H ISRE D++A Sbjct: 124 VPMS-HGVDFHPGLSRNVAKAAGM------------MGLTAEMLSRLHGISREMQDQFAA 170 Query: 185 QSQQRWKAANDAGYFNDEMAPIEVKTKKG-KQTMQVDEHARPQTTLEQLQKLPPVFKK-D 242 +S R AA +G F E+ P G + DE RP+TT+E L L P F Sbjct: 171 RSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFDPVS 230 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 GTVTAG +S ++DGA A+++ SE ++ P ARI V GCDPSIMG GPVPA Sbjct: 231 GTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKL 290 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD---ISKTNVNGGAIALGHPLGGSGS 359 ALKKAGLS D+D+ E+NEAFA Q L + L L K N+NGGAIALGHPLG SG+ Sbjct: 291 ALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGA 350 Query: 360 RITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 RI+ L++ + R+ ++ + + CIG GQGIA + + Sbjct: 351 RISTTLINLMERKDAQFGLATMCIGLGQGIATVFE 385 >2WUA-A nrPDB Length = 440 Score = 253 bits (646), Expect = 9e-68, Method: Compositional matrix adjust. Identities = 152/397 (38%), Positives = 220/397 (55%), Gaps = 20/397 (5%) Query: 7 VFVVAAKRTPF-GAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 V +VAA R+P A G LKD D+ KA + ++P V +++G+VL + S Sbjct: 35 VVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGSQ 94 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 R G P+ P T+NR C SG Q++ + I ++ + G ESM+ Sbjct: 95 RASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTAN 154 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 P K+ + + +D L LPM +T+EN+A K I+R+E D+ A+ Sbjct: 155 PMAWEG-SVNPKVKTMAQAQDCL----------LPMGITSENVAQKFSITRQEQDQAAVG 203 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKT---KKGKQ---TMQVDEHARPQTTLEQLQKLPPVF 239 S ++ AA AG F DE+ PI+ K K G + T+ VD+ RP T+L L KL PVF Sbjct: 204 SHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGIRPGTSLADLAKLKPVF 263 Query: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 +KDG+ TAG +S V+DGAGAV++ + L + G PSIMGIGP A Sbjct: 264 RKDGSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVGVPPSIMGIGPAVA 323 Query: 300 ISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 I A+K AGL + D+DL E+NEAFA Q++ ++ L++D K NVNGGA+A+GHPLG +G+ Sbjct: 324 IPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATGA 383 Query: 360 RITAHLVHELRRRG--GKYAVGSACIGGGQGIAVIIQ 394 R A L+HE++RRG ++ V S CIG G G A + + Sbjct: 384 RCVATLLHEMKRRGRDCRFGVVSMCIGTGMGAAAVFE 420 >6ARG-A nrPDB Length = 399 Score = 250 bits (639), Expect = 7e-67, Method: Compositional matrix adjust. Identities = 150/397 (37%), Positives = 229/397 (57%), Gaps = 4/397 (1%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALS-AGKVSPETVDSVIMGNV 59 M+ L V++V++ RTP G++ G L TA L A KAAL+ + P V V GNV Sbjct: 2 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNV 61 Query: 60 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 119 + S++ AR L G+ + T T+N++C SG ++I+ G Q I A+VV+ GGT Sbjct: 62 I-SANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGT 120 Query: 120 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 ESMS AP+ + N+R G K G ++ + LTD Q M + AE A H SRE+ Sbjct: 121 ESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQ 180 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQT-TLEQLQKLPPV 238 D+YA+++ ++ +AA AG F++E+API++ +GK + V + P+ E+L+ + P Sbjct: 181 DEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPA 240 Query: 239 F-KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPV 297 F GTVTA N+S + DGA AV++ SE +K+ N P+A+I+G+ + PS P Sbjct: 241 FIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPA 300 Query: 298 PAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGS 357 AI ALK AG+ +D E+NEAF+ LA + L + K N++GGA+A+GHP+G S Sbjct: 301 LAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGAS 360 Query: 358 GSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 G+RI L+ L+ + GK C GGG A++++ Sbjct: 361 GARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVE 397 >2C7Y-A nrPDB Length = 404 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 152/397 (38%), Positives = 215/397 (54%), Gaps = 20/397 (5%) Query: 7 VFVVAAKRTPF-GAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 V +VAA RTP + G KD DL +A + ++P V +++G VL S Sbjct: 15 VVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGSQ 74 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 R G P+ T+NR C SG Q++ + I ++ + G ESM+ Sbjct: 75 RASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTTN 134 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 P + + + ++ Q+ LPM +T+EN+A + +SR+E D+ A+ Sbjct: 135 P-----------MAWEGSVNPAVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAVD 183 Query: 186 SQQRWKAANDAGYFNDEMAPIEVK---TKKGKQ---TMQVDEHARPQTTLEQLQKLPPVF 239 S ++ AA AG F DE+ P++ K K G + T+ VD+ RP TTL L KL PVF Sbjct: 184 SHRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPVF 243 Query: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 KKDGT TAGN+S V+DGAGAV++ + L + G DP+IMGIGP A Sbjct: 244 KKDGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAVA 303 Query: 300 ISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 I A+K AGL L D+DL E+NEAFA Q++ L LD K NVNGGA+A+GHPLG +G+ Sbjct: 304 IPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATGA 363 Query: 360 RITAHLVHELRRRGG--KYAVGSACIGGGQGIAVIIQ 394 R A L+HE++RRG ++ V S CIG G G A + + Sbjct: 364 RCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVFE 400 >1WDK-C nrPDB Length = 390 Score = 241 bits (616), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 154/397 (38%), Positives = 210/397 (52%), Gaps = 20/397 (5%) Query: 5 RGVFVVAAKRTPFG-AYGGLLKDFTATDLS-EFAAKAALSAGKVSPETVDSVIMGNVLQS 62 R V +V RTP G + GG+ ++ A D+S +K KV P V+ VI G V Q+ Sbjct: 5 RDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQT 64 Query: 63 SSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM 122 +AR L IP + A T++RLCGS ++ Q I +V + GG E M Sbjct: 65 LEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHM 124 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKY 182 G D SL+ + M +TAE L H ISRE+ D + Sbjct: 125 GHVSMM---------HGVDPNPHMSLYAAKASGM----MGLTAEMLGKMHGISREQQDAF 171 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKG-KQTMQVDEHARPQTTLEQLQKLPPVFK- 240 A++S Q A G F DE+ P++ + G + DE RP TTLE L L P F Sbjct: 172 AVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNP 231 Query: 241 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 300 K GTVTAG +S + DGA +I+ S K PLA I V+G DP+IMG GPVPA Sbjct: 232 KGGTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPAT 291 Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERS---LDLDISKTNVNGGAIALGHPLGGS 357 ALK+AGL++ D+D +E+NEAFA Q L V + LD K N++GGAIALGHP G S Sbjct: 292 QKALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCS 351 Query: 358 GSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 G+RI+ L++ +++ GG + + + CIG GQGIA + + Sbjct: 352 GARISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFE 388 >5XYJ-B nrPDB Length = 408 Score = 239 bits (609), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 150/400 (37%), Positives = 226/400 (56%), Gaps = 10/400 (2%) Query: 2 ALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKV----SPETVDSVIMG 57 ++ + V++V+ RTP G++ G L TA +L A K AL+ KV + + D +I G Sbjct: 10 SMSQNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALA--KVPELDASKDFDEIIFG 67 Query: 58 NVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCG 117 NVL S++ AR V L G+ A T+N++ S ++I+ G Q I A+VV+ G Sbjct: 68 NVL-SANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAG 126 Query: 118 GTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISRE 177 G ESM+ APY + R G K G + ++ L D + L M + AE A I+RE Sbjct: 127 GCESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITRE 186 Query: 178 ECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARP-QTTLEQLQKLP 236 + D +A++S Q+ + + G F++E+ P+ +K +GK QV + P + +E+L+ Sbjct: 187 QQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSAR 246 Query: 237 PVFKKD-GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIG 295 VF+K+ GTVTA NAS + DGA AVI+ SE +K+ N PLA I G+ + P+ Sbjct: 247 TVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWA 306 Query: 296 PVPAISGALKKAGLS-LKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPL 354 P A+ ALK AG+ + +D E NEAF+ L + L LD SK NV GGA+ALGHPL Sbjct: 307 PSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPL 366 Query: 355 GGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 G SG+R+ L+ L++ GGK V + C GGG +++I+ Sbjct: 367 GCSGARVVVTLLSILQQEGGKIGVAAICNGGGGASSIVIE 406 >2IIK-A nrPDB Length = 418 Score = 234 bits (596), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 154/395 (38%), Positives = 210/395 (53%), Gaps = 19/395 (4%) Query: 7 VFVVAAKRTPFGAYG-GLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 V VV +RT G G KD T +L A L + PE + + +GNVLQ + Sbjct: 32 VVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAG 91 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 AI +AR IP+ P T+NR C SG Q++ + I ++ + G ESMS A Sbjct: 92 AI-MARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLA 150 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 G+ + L + +PM +T+EN+A + ISRE+ D +AL Sbjct: 151 -----------DRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQDTFALA 199 Query: 186 SQQRWKAANDAGYFNDEMAPIE--VKTKKGKQ---TMQVDEHARPQTTLEQLQKLPPVFK 240 SQQ+ A G F E+ P+ V KG + T+ DE RP TT+E L KL P FK Sbjct: 200 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 259 Query: 241 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 300 KDG+ TAGN+S V+DGA A+++A ++ L + Y V G P IMGIGP AI Sbjct: 260 KDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAI 319 Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 360 AL+KAGL++ D+D+ E+NEAFA Q L L K N GGA+ALGHPLG +G+R Sbjct: 320 PVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGAR 379 Query: 361 ITAHLVHELRRRGGK-YAVGSACIGGGQGIAVIIQ 394 L++EL+RRG + Y V S CIG G G A + + Sbjct: 380 QVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 414 >3SVK-A nrPDB Length = 407 Score = 231 bits (590), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 138/368 (37%), Positives = 194/368 (52%), Gaps = 41/368 (11%) Query: 51 VDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKE 110 + +I+G V +AR L G+P+ T + +NR C SG +++ Q++ Sbjct: 55 ISDMILGVVSPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGW 114 Query: 111 AEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQL---PMAMTAEN 167 ++VL GG ESMS+ P +GSD W + + + ++ P + A+ Sbjct: 115 DDLVLAGGVESMSRVP-----------MGSD----GGAWATDPETNYRIGFVPQGIGADL 159 Query: 168 LAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQT 227 +A SRE+ D YAL+SQQ+ AA GYF + P V+ + G + DEH RP T Sbjct: 160 IATLEGFSREDVDAYALRSQQKAAAAWSGGYFAKSVVP--VRDQNGLVILDHDEHMRPDT 217 Query: 228 TLEQLQKLPPVFKKDGTV---------------------TAGNASGVADGAGAVIIASED 266 T+E L KL F G + T GN+SG+ DGA V++ SE Sbjct: 218 TMEGLAKLKTAFDGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEK 277 Query: 267 AVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQ 326 A K TP ARIV SG DP IM GP PA L +AGL++ D+DL E+NEAFA Sbjct: 278 AGKSQGLTPRARIVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASV 337 Query: 327 YLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGG 386 L ++ L++ K NVNGGAIA+GHPLG +G+ IT +V EL RR + A+ + CIGGG Sbjct: 338 VLKFQKDLNIPDEKLNVNGGAIAMGHPLGATGAMITGTMVDELERRNARRALITLCIGGG 397 Query: 387 QGIAVIIQ 394 G+A II+ Sbjct: 398 MGVATIIE 405 >6BJA-A nrPDB Length = 397 Score = 229 bits (584), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 135/394 (34%), Positives = 216/394 (54%), Gaps = 11/394 (2%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 + V++++A RTP ++ L +A DL K A+ + ++ I+GNVL S+ Sbjct: 9 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVL-SAG 67 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 +AR + + IPK + +TIN++C S ++I+ G Q I V +V+ G+ESMS Sbjct: 68 LGQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSN 127 Query: 125 APYCVR--NVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKY 182 AP+ V + FG D D L S+ Q PM + AE + +RE+ D Y Sbjct: 128 APFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQ----PMGLCAEKTVKDYAFTREQLDAY 183 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 242 A++S ++ + A G FN E+ P+ V K+G + + ++ + E++ L P F KD Sbjct: 184 AIESYRKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIPEKVPALHPAFLKD 243 Query: 243 G--TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 300 G T+TA NAS + DGA A ++AS + V++ P+A+++ Y +G +P + P A+ Sbjct: 244 GSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAV 303 Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 360 L ++GL + + L E+NEAF+ LA + L LD + NV GGA+ALGHPLG SG+R Sbjct: 304 KQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGAR 363 Query: 361 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 I LVH L + + V + C GGG+ A++I+ Sbjct: 364 IVVTLVHAL--KSDELGVAAICNGGGEASAILIK 395 >6BJB-A nrPDB Length = 393 Score = 221 bits (563), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 140/367 (38%), Positives = 197/367 (53%), Gaps = 10/367 (2%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 V V A RTP G++ + T L A K AL V P V +G V+ S++ Sbjct: 10 VVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNAGQ 69 Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 AR V L G T +N++ SG ++I + + E+V+ GG ESMS P Sbjct: 70 -GPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCVP 128 Query: 127 YCVR--NVRFG-TKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 + + + FG TKL I + L D + + M A+ +A + I+REE DKYA Sbjct: 129 FYLPRGEIPFGGTKLIDGIPRD-----GLNDVYNDILMGACADKVAKQFAITREEQDKYA 183 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 + S +R AA G F E+ P+EV K T++ DE + + E++ KL P F +G Sbjct: 184 ILSYKRSAAAWKEGIFAKEIIPLEVTQGKKTITVEEDEEYK-KVNFEKIPKLKPAFTSEG 242 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 +VTA NAS + DGA V++ + D KKH PLAR++ Y + P GI P I Sbjct: 243 SVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKV 302 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 LK AGL +KD+DL E+NEAFA L ++L LD SK N++GGA++LGHP+G SG+RI Sbjct: 303 LKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVG 362 Query: 364 HLVHELR 370 HLVH L+ Sbjct: 363 HLVHTLK 369 >4B3J-C nrPDB Length = 403 Score = 219 bits (559), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 136/365 (37%), Positives = 188/365 (51%), Gaps = 35/365 (9%) Query: 51 VDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKE 110 + VI+G V +AR L G+P + + +NR C SG +++ Q++ Sbjct: 51 ISDVILGCVSPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGW 110 Query: 111 AEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAV 170 ++VL GG ESMS+ P G ++ D ++V P ++ A+ +A Sbjct: 111 DDLVLAGGVESMSRVPMGSDGGAMGLDPATNY---DVMFV---------PQSIGADLIAT 158 Query: 171 KHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLE 230 SRE+ D YAL+SQQ+ A GYF + P V+ + G + DEH RP TT E Sbjct: 159 IEGFSREDVDAYALRSQQKAAEAWSGGYFAKSVVP--VRDQNGLLILDHDEHMRPDTTKE 216 Query: 231 QLQKLPPVF---------------------KKDGTVTAGNASGVADGAGAVIIASEDAVK 269 L KL P F K + T GN+SG+ DGA V+I S A K Sbjct: 217 GLAKLKPAFEGLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGK 276 Query: 270 KHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLA 329 TP ARIV SG DP IM GP PA L +AGL++ D+DL E+NEAFA L Sbjct: 277 LQGLTPRARIVATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLK 336 Query: 330 VERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGI 389 ++ L++ K NVNGGAIA+GHPLG +G+ I +V EL RR + A+ + CIGGG G+ Sbjct: 337 FQKDLNIPDEKLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGV 396 Query: 390 AVIIQ 394 A II+ Sbjct: 397 ATIIE 401 >1PXT-A nrPDB Length = 390 Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 143/395 (36%), Positives = 203/395 (51%), Gaps = 24/395 (6%) Query: 7 VFVVAAKRTPFG-AYGGLLKDFTATD------LSEFAAKAALSAGKVSPETVDSVIMGNV 59 V +VAA R+ G + G KD TD L+EF + + ++ V GNV Sbjct: 9 VVIVAANRSAIGKGFKGAFKDVN-TDYLLYNFLNEFIGRFP-EPLRADLNLIEEVACGNV 66 Query: 60 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 119 L + A R L GIP TP + +NR C SG ++ + +I V + ++ L G Sbjct: 67 LNVGAGATE-HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 125 Query: 120 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 ESM+ N + LG + + L + + +PM +T EN+A KISR++ Sbjct: 126 ESMTN------NYKNVNPLG--MISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQ 177 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF 239 D++A S Q+ A + G F DE+ PI++ Q DE RP T E L + P F Sbjct: 178 DEFAANSYQKAYKAKNEGLFEDEILPIKLPDG---SICQSDEGPRPNVTAESLSSIRPAF 234 Query: 240 KKD-GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 298 KD GT TAGNAS V+DG V++A + N L R + + G P IMG+GP Sbjct: 235 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 294 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 AI L+ GL ++D+D+ E+NEAFA Q L L +D++K N GGAIALGHPLG +G Sbjct: 295 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 354 Query: 359 SRITAHLVHELRRRGGKYAVGSACIGGGQGIAVII 393 +R A ++ EL++ + V S CIG G G A I Sbjct: 355 ARQVATILRELKK--DQIGVVSMCIGTGMGAAAIF 387 >5ZQZ-B nrPDB Length = 474 Score = 201 bits (512), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 146/429 (34%), Positives = 214/429 (49%), Gaps = 45/429 (10%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R V VV RTPF G KD DL+ A L V E VD +I G V+Q Sbjct: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + +AR L G +TPA T+ C S Q++ G I + +V++ GG E MS Sbjct: 111 KTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSL--WVSLTDQH------VQLP----------MAMTA 165 P +R+ R KL D+ S+ +SL + +LP M +A Sbjct: 170 DVP--IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 Query: 166 ENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARP 225 + LA +SR E D+YAL+S K A D G +D + P +V GK T+ D RP Sbjct: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP---GKDTVTKDNGIRP 283 Query: 226 QTTLEQLQKLPPVF-KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFV 284 ++LEQ+ KL P F K GTVTA N+S + DGA A++I +E+ + P A + + Sbjct: 284 -SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMY 342 Query: 285 SGCDPS-IMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD------ 337 DP + +GP A L+KAGL++ D+D E +EAF+ Q LA +++D D Sbjct: 343 VSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENY 402 Query: 338 -----------ISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGG 386 + K N GG+++LGHP G +G R+ + LR+ GG+Y + +AC GG Sbjct: 403 MGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGG 462 Query: 387 QGIAVIIQS 395 QG A+I+++ Sbjct: 463 QGHAMIVEA 471 >4UBW-A nrPDB Length = 399 Score = 187 bits (475), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 133/399 (33%), Positives = 200/399 (50%), Gaps = 28/399 (7%) Query: 9 VVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPE----TVDSVIMGNVLQSSS 64 +V A R+P G G L AT+L KA + + V+ VI G V Q Sbjct: 14 IVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQFGE 73 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQS--IVNGCQEICVKEAEVVLCGGTESM 122 + ++R L G+P+ A T++ CGSG Q+ ++ G I +V + G E+M Sbjct: 74 QSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGL--IAAGAIDVGIACGIEAM 131 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAM-TAENLAVKHKISREECDK 181 S+ V G G D L + + LP AE +A + I+RE+ D Sbjct: 132 SR-------VGLGANAGPDRSL-----IRAQSWDIDLPNQFEAAERIAKRRGITREDVDV 179 Query: 182 YALQSQQRWKAANDAGYFNDEMAPI------EVKTKKGKQTMQVDEHARPQTTLEQLQKL 235 + L+SQ+R + A G F+ E++PI E G++ + + +TT+ L +L Sbjct: 180 FGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLRETTMAGLGEL 239 Query: 236 PPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIG 295 PV + G TAG +S ++DGA AV+ E + H TP ARIV + G +P G Sbjct: 240 KPVLEG-GIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDG 298 Query: 296 PVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLG 355 PV + + L+KAG+ + D+D+VE+NEAFA L+ R + D+ + NVNGGAIALGHP+G Sbjct: 299 PVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVG 358 Query: 356 GSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 +GSR+ +HEL R A+ + C GG II+ Sbjct: 359 CTGSRLITTALHELERTDQSLALITMCAGGALSTGTIIE 397 >6ESQ-A nrPDB Length = 392 Score = 48.9 bits (115), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 87/405 (21%), Positives = 145/405 (35%), Gaps = 87/405 (21%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNV---- 59 +R V ++ +T FG L + + DL A A+ V +D++ +GN+ Sbjct: 1 MRDVAIIGYGQTKFGE----LWEDSFRDLIVEAGVKAIKDANVDGGDIDAMYIGNMSGGL 56 Query: 60 -LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGG 118 + A +A H GL P + C SG ++ + + +VVL GG Sbjct: 57 FVGQEHIASLIADHAGLN-----PVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAGG 111 Query: 119 TESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREE 178 E M+ + + D W + AM A ++ ++ EE Sbjct: 112 VEKMTDVEDATAAIASAS---------DQEWEAFFGATFPSLYAMMARRYMYQYGLTIEE 162 Query: 179 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV 238 +++ + + K K + + TTLEQ+ PV Sbjct: 163 LSMWSVIAHEN-----------------ATKNKYAQFGFK--------TTLEQVMNASPV 197 Query: 239 FKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGC----------- 287 +T + S V+DGA A+I+ DA K F P I+ Y + Sbjct: 198 ADP---LTLMHCSPVSDGASALIVC--DADKAEEFAPKDEII-YIKASTQASDTIALHDR 251 Query: 288 -DPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDL---------- 336 D + + V A A K A ++ + +D+ EV++ FA L + L Sbjct: 252 EDMTTLNAAKV-ASEKAYKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVI 310 Query: 337 ----------DISKTNVNGGAIALGHPLGGSGSRITAHLVHELRR 371 D N +GG A GH LG +G R L +L++ Sbjct: 311 DEGKIRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQ 355 >6HRV-A nrPDB Length = 421 Score = 44.7 bits (104), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 83/414 (20%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS-- 64 VFV+ T F G +D D+++ A + AL+ + + +G V S+ Sbjct: 16 VFVIGVGMTKFEKPGA--RDIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVYGDSTCG 73 Query: 65 -DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 AIY +GL GIP + +N C +G ++ G Q I A+ VL G E M Sbjct: 74 QRAIY--HSLGLS-GIP----IINVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKME 126 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLP-----MAMTAENLAVKHKISREE 178 + + + + D+H+++ +A + RE Sbjct: 127 RGSLSSKYMDRTNPM---------------DKHMEVMINRYGLAAVPAAPQMFGNAGREH 171 Query: 179 CDKYALQSQQRWKAA--NDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLP 236 +KY + + K A N N+ + + DE+ +LEQ+ Sbjct: 172 MEKYGTKPEHFAKVAWKNHKHSTNNPYSQFQ------------DEY-----SLEQVIDSR 214 Query: 237 PVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLA-RIVG----------YFVS 285 VF+ +T +DGAGA ++ASE V+++ A IV + + Sbjct: 215 KVFE---FLTLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEEN 271 Query: 286 GCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD-------- 337 C + A AG+ D+D++E+++ F+ L +L L Sbjct: 272 SCMKMVGYDMTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGEL 331 Query: 338 ISK----------TNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSA 381 I + N +GG I+ GHPLG +G A L +LR G V A Sbjct: 332 IDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRAEAGPRQVPGA 385 >5M3K-C nrPDB Length = 398 Score = 44.3 bits (103), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 91/412 (22%), Positives = 149/412 (36%), Gaps = 96/412 (23%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 R V +V+A TP + + F + +A AL K+ P + +V G + S Sbjct: 4 RRVAIVSAAYTPKPGSSRVRQTFKEMIVE--SAYKALKDAKMHPREIQAVAYGYHGEGIS 61 Query: 65 DAIYLARHVGLRVGI-PKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + L + +GI P T T N C S S G Q + E ++VLCGG E M+ Sbjct: 62 EYGGLGPTISDALGISPAPTFMSTAN--CTSSSVSFQMGHQMVASGEYDIVLCGGFEKMT 119 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 + + +GS + E + L + H D +A Sbjct: 120 D------HFNYAEYIGSSTECEYDYF------------------LGISHT------DAFA 149 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 L + + ++ AG D +A G+Q M++ P T Q +P + Sbjct: 150 LATAEYFQKFGYAGREADVLATF------GRQ-MRIYAQNTPTAT-RYGQPIPSLEVLKN 201 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGC--------------DP 289 + G+ + +G I+ +E K+ P+ FV GC +P Sbjct: 202 SEACGSMLAWGEASGCAILVAEHLAHKYTDKPV------FVRGCAYTGVSHYFGTRFHNP 255 Query: 290 SIMGIGPVPAISG-------------ALKKAGLSLKDMDLVEVNEAFAPQYLAVER---- 332 ++ G +P G A KKAG++ KD+D+ +V + + +E Sbjct: 256 TLHHPG-LPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGAGLIQMESMGIC 314 Query: 333 --------------SLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELR 370 +LD + N +GG I GH G G L +LR Sbjct: 315 GKGQAGDFVLEGGIALDGQL-PLNTDGGNIGRGHASGCDGILHITELFRQLR 365 >4BI9-A nrPDB Length = 454 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 59/228 (25%), Positives = 95/228 (41%), Gaps = 42/228 (18%) Query: 188 QRWKAANDAGYFN--DEMAPIEVKTKKGKQTMQVDEHARPQTTLE---QLQKLPPVFKKD 242 +R KA +AG+F D G + HAR + TL+ Q P F + Sbjct: 201 RRMKAIQEAGHFTMEDAAYVAAKAYASGNRNPLAHMHAR-KVTLDFCTQASDKNPNFLGN 259 Query: 243 GT----VTAGNASGVADGAGAVIIASEDAVKKHNFTP----------LARIVG-YFVSGC 287 + + S V+DG AVI+ASE+ ++K +P LA G + Sbjct: 260 EIYKPFLRTTDCSQVSDGGAAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSP 319 Query: 288 DPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYL---------------AVER 332 D + M V A + AL AG+ + + + EV++ F L A+ R Sbjct: 320 DLTRMTTSMVAART-ALSMAGVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIR 378 Query: 333 S----LDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKY 376 S LD I N GG ++ GHP+G +G + + +++ + G+Y Sbjct: 379 SGATALDGRI-PVNTGGGLLSFGHPVGATGVKQVLEVYRQMKGQCGEY 425 >4YZO-A nrPDB Length = 373 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 71/326 (21%), Positives = 129/326 (39%), Gaps = 66/326 (20%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIK 143 P+L ++ GSG +I+ + KEA VL G E MS+ + R TK+ S + Sbjct: 68 PSLRVDNTSGSGGSAILVAKSLLESKEANTVLVVGVEKMSE-----KKTREVTKIISSL- 121 Query: 144 LEDSLWVSLTDQHVQLP--MAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFND 201 + ++ LP +++A K RE + A+++ ++N Sbjct: 122 ------LPFEERIASLPSLASISAIEYMRKFNAPRESIAQVAVKN-----------HYNG 164 Query: 202 EMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVI 261 + P H + + TLE++ P + + + + ++DGA AV+ Sbjct: 165 SLNPFA--------------HIQKRVTLEEVLNSPVISE---PLRLYEYTPISDGAAAVV 207 Query: 262 -IASEDAVKKHNFTPLARIVGY-----FVSGCDPSIMGIGPVPAISGALKKAGLSLKDM- 314 + +EDA+ + + +G +VS + + V A A KKA + D Sbjct: 208 MVRNEDALSYTSKPVYIKGIGSSNYTAYVSEKEDFVTLPAVVEASRKAFKKAKVERIDFA 267 Query: 315 ---DLVEVNEAFAPQYLAVER-------------SLDLDISKTNVNGGAIALGHPLGGSG 358 D+ + E + + + + SLD +I N +GG + GHP+G SG Sbjct: 268 ELHDMATILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEIP-INPSGGLNSKGHPIGASG 326 Query: 359 SRITAHLVHELRRRGGKYAVGSACIG 384 ++R G V +A +G Sbjct: 327 VAQAVEAFSQIRNEAGNRQVKNARVG 352 >4QAV-A nrPDB Length = 415 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 8/114 (7%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGI---GPVPAISGALKKAGL 309 + +GAG +++ + KK A IVG+ +S I GP A++ ALK AG+ Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGI 292 Query: 310 SLKDMDLVEVNEAFAP-----QYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 + +D+D V + P + A++R+ KT V+ GH LG +G Sbjct: 293 NPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAG 346 >2IX4-A nrPDB Length = 431 Score = 36.6 bits (83), Expect = 0.021, Method: Compositional matrix adjust. Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 12/119 (10%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +G+G +++ + K+ A + GY +SG P G G V A++ AL+++ Sbjct: 248 IGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPEDGKGAVLAMTRALRQS 307 Query: 308 GLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIAL-------GHPLGGSGS 359 GL +D V + P AVE + + G +A GH LG +G+ Sbjct: 308 GLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKGATGHLLGAAGA 366 >5LNQ-A nrPDB Length = 457 Score = 35.8 bits (81), Expect = 0.036, Method: Compositional matrix adjust. Identities = 32/150 (21%), Positives = 65/150 (43%), Gaps = 28/150 (18%) Query: 249 NASGVADGAGAVIIASEDAVKKHNFTPL-ARIVGYFVSGCDPSIMGIGP---------VP 298 + S V+DG V++A+E+ ++K +P +R+V C S + P Sbjct: 273 DCSQVSDGGAGVVLANEEGLRKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQ 332 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDL-------DISKT---------- 341 A AL A + D+++ EV++ F + + +L + D+ + Sbjct: 333 AAQKALSMANIKPSDLNVAEVHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIP 392 Query: 342 -NVNGGAIALGHPLGGSGSRITAHLVHELR 370 N GG ++ GHP+G +G + + +++ Sbjct: 393 VNTGGGLLSFGHPVGATGIKQIMEVYRQMK 422 >2GP6-A nrPDB Length = 434 Score = 34.3 bits (77), Expect = 0.094, Method: Compositional matrix adjust. Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 18/99 (18%) Query: 27 FTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPAL 86 F+ D+ KA VSP TV + ++ A+ L RH V P Sbjct: 140 FSYDDMRARGMKA------VSPLTVQKYMP----NGAAAAVGLERHAKAGVMTPVSA--- 186 Query: 87 TINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 C SG ++I Q+I + EA+ +CGG E+ +A Sbjct: 187 -----CASGAEAIARAWQQIVLGEADAAICGGVETRIEA 220 >5W2O-A nrPDB Length = 439 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 12/76 (15%) Query: 45 KVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQ 104 KVSP V +IM N A + +G R G+ +T C SG ++I + + Sbjct: 159 KVSPLAV-QMIMPN-----GAAAVIGLQLGARAGV------MTPVSACSSGSEAIAHAWR 206 Query: 105 EICVKEAEVVLCGGTE 120 +I + +A+V +CGG E Sbjct: 207 QIVMGDADVAVCGGVE 222 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 37/124 (29%), Positives = 57/124 (45%), Gaps = 12/124 (9%) Query: 257 AGAV-IIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKAGLS 310 AGA+ +I +E+ K PLAR++G ++ P+ G+ A++ +L+ AGLS Sbjct: 265 AGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLS 324 Query: 311 LKDMDLVEVNEAFAPQYLAVE----RSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLV 366 D+D V + P A E R D + V ALGH +G G+ + V Sbjct: 325 PADIDHVNAHGTATPIGDAAEANAIRVAGCD--QAAVYAPKSALGHSIGAVGALESVLTV 382 Query: 367 HELR 370 LR Sbjct: 383 LTLR 386 >1J3N-A nrPDB Length = 408 Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust. Identities = 32/134 (23%), Positives = 59/134 (44%), Gaps = 17/134 (12%) Query: 236 PPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPS 290 P +DG V + +GAG +++ + + KK A +VG+ S +P Sbjct: 219 PFTLSRDGFV-------MGEGAGVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPH 271 Query: 291 IMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAP-----QYLAVERSLDLDISKTNVNG 345 G G A++ ALK AG++ + + + + P + LA++R + V+ Sbjct: 272 PEGKGAALAMARALKDAGIAPEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSS 331 Query: 346 GAIALGHPLGGSGS 359 +GH LG +G+ Sbjct: 332 TKSMIGHLLGAAGA 345 Score = 32.7 bits (73), Expect = 0.28, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 H+ +R G P+ T+ C +G ++ + + I + EA++VL GGTE+ Sbjct: 143 HIAMRYGF--TGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTEA 190 >3E60-A nrPDB Length = 424 Score = 32.3 bits (72), Expect = 0.34, Method: Compositional matrix adjust. Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 9/109 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GA V++ + KK A I+GY +SG PS G G ++ ALK+A Sbjct: 243 MGEGAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRA 302 Query: 308 GLSLKDMDLVEVN----EAFAPQYLAVERSLDLDISKTNVNGGAIALGH 352 +++ ++D + + A + AVER L + +++ ++GH Sbjct: 303 QVNVSELDYINAHGTSTMADVIELAAVERVLGYYAPQVSMSSTKSSIGH 351 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 29/50 (58%), Gaps = 2/50 (4%) Query: 72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 +V ++ G+ P ++ C +G +I + + I + +A+V+L GGTES Sbjct: 156 YVSIKYGL--RGPNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTES 203 >4R8E-A nrPDB Length = 413 Score = 32.0 bits (71), Expect = 0.44, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 10/128 (7%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + DGAG +++ + KK A +VG+ +S P G G A+ AL+ A Sbjct: 232 LGDGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDA 291 Query: 308 GLSLKDMDLVEVNEAFAP-----QYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 G++ + + + P + AV+ D K V+ GH LG +G+ + Sbjct: 292 GITTSQIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGAVES 351 Query: 363 AHLVHELR 370 V LR Sbjct: 352 IFTVLALR 359 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 12/79 (15%) Query: 45 KVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQ 104 K+SP V S I+ + A +L GLR P+++I C SG +I + + Sbjct: 129 KISPFFVPSTIVNMI------AGHLTIMYGLR------GPSISIATACTSGVHNIGHAAR 176 Query: 105 EICVKEAEVVLCGGTESMS 123 I +A+V++ GG E S Sbjct: 177 IIAYNDADVMVAGGAEKAS 195 >6QSP-A nrPDB Length = 406 Score = 31.6 bits (70), Expect = 0.70, Method: Compositional matrix adjust. Identities = 16/59 (27%), Positives = 34/59 (57%), Gaps = 6/59 (10%) Query: 68 YLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 +LAR++ + E PA T++ C S ++I++G + I + + + GG +++S+ P Sbjct: 156 FLARYLAI------EGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMP 208 >3O04-A nrPDB Length = 413 Score = 31.2 bits (69), Expect = 0.73, Method: Compositional matrix adjust. Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 20/121 (16%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG VI+ + K A IVGY +G P+ G G A+ A+ A Sbjct: 231 IGEGAGIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDA 290 Query: 308 GLSLKDMDLVEV-------NEAFAPQYLAV---ERSLDLDISKTNVNGGAIALGHPLGGS 357 GL+ +D + N+ + Q + E + L IS T GH LG S Sbjct: 291 GLTPDKVDYINAHGTSTPYNDEYETQAIKTVFGEHAKKLAISSTKS-----MTGHTLGAS 345 Query: 358 G 358 G Sbjct: 346 G 346 >6GC1-A nrPDB Length = 579 Score = 31.2 bits (69), Expect = 0.87, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Query: 117 GGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISR 176 GG + Q +V FGT GS+++ D LW+++ H + + + L K+++++ Sbjct: 333 GGAKGEQQPISSPWDVVFGTS-GSEVQRGDILWIAMAGTHQIWALLLDSGKLPKKNELTK 391 Query: 177 EECDKYA 183 C ++A Sbjct: 392 GTCLRFA 398 >1OXH-A nrPDB Length = 430 Score = 30.8 bits (68), Expect = 1.00, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLK 312 + +G+G +++ S + +K T LA +VGY + CD M P P GA+K L+L+ Sbjct: 250 MGEGSGMLVLESLEHAEKRGATILAEVVGY-GNTCDAYHM-TSPHPEGQGAIKAIKLALE 307 Query: 313 DMDL 316 + ++ Sbjct: 308 EAEI 311 >4JPF-A nrPDB Length = 436 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 6/53 (11%) Query: 68 YLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 +L+ H+GL + P + C +G SI + I EA+V++ GG+E Sbjct: 168 FLSIHLGL------QGPNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSE 214 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 ++DG+GA+++ + + A +VG+ +SG P G G + AL+ A Sbjct: 254 LSDGSGALVLEELEHARARGARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDA 313 Query: 308 GLSLKDMDLVEVNEAFAP 325 GL + +D + + P Sbjct: 314 GLDPRQVDYINAHGTSTP 331 >2GQD-A nrPDB Length = 437 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 10/116 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG ++I S ++ + A IVGY +G P+ G G A+ A+ A Sbjct: 255 MGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDA 314 Query: 308 GLSLKDMDLVEVNEAFAP-----QYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 G+ KD+ + + P + A++ + V+ GH LG +G Sbjct: 315 GIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATG 370 >1PWH-A nrPDB Length = 327 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/30 (50%), Positives = 18/30 (60%), Gaps = 2/30 (6%) Query: 68 YLARHVGL--RVGIPKETPALTINRLCGSG 95 Y AR +GL + +P TPALTI RL G Sbjct: 74 YAARRLGLPATIVVPSTTPALTIERLKNEG 103 >4JRH-A nrPDB Length = 417 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 11/118 (9%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + DGAG +++ + K A +VG+ +SG PS G G A+ A++ A Sbjct: 235 LGDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDA 294 Query: 308 GLSLKDMDLVEVNEAFAP-----QYLAVERSL-DLDISKTNVNGGAIALGHPLGGSGS 359 G++ + + V + P + ++R+L + + V+ GH LG +GS Sbjct: 295 GVTGEQIGYVNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGS 352 >3LM6-A nrPDB Length = 346 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 16/68 (23%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Query: 32 LSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRL 91 L E A AL ++ + +D ++ G++L + A Y+ARH+ + P L + Sbjct: 58 LMEDAVNVALQKNNLTKDDIDLLLAGDLLNQNVTANYVARHLKI--------PFLCMFGA 109 Query: 92 CGSGFQSI 99 C + +++ Sbjct: 110 CSTSMETV 117 >5BY7-A nrPDB Length = 360 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 6/74 (8%) Query: 28 TATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIY--LARHVGLRVGIPKETPA 85 T DL+ A AL A V+PE VD V++G ++ D + A V R+GI PA Sbjct: 80 TLADLAHQAGSRALDAAGVTPEEVDLVVLGT---ATPDRLMPTTATVVADRLGI-DGVPA 135 Query: 86 LTINRLCGSGFQSI 99 + C Q++ Sbjct: 136 YQLQSGCSGAVQAL 149 >2IWZ-A nrPDB Length = 438 Score = 27.7 bits (60), Expect = 8.5, Method: Compositional matrix adjust. Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 17/130 (13%) Query: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGI 294 K+DG V + +GA +++ + + A ++GY +SG P G Sbjct: 249 KRDGFV-------MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGE 301 Query: 295 GPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAI-----A 349 G + ++ ALK AG+ +++ + + P A E + K + A+ A Sbjct: 302 GALRCMAAALKDAGVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKGA 361 Query: 350 LGHPLGGSGS 359 GH LG +G+ Sbjct: 362 TGHLLGAAGA 371 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4C2K-A nrPDB 519 e-148 4N44-A nrPDB 508 e-144 4E1L-A nrPDB 499 e-142 4DD5-A nrPDB 488 e-138 3SS6-A nrPDB 484 e-137 1NL7-A nrPDB 465 e-131 1ULQ-A nrPDB 463 e-131 6BN2-A nrPDB 461 e-130 1WL4-A nrPDB 461 e-130 4O9A-A nrPDB 456 e-129 4NZS-A nrPDB 455 e-128 6ARG-A nrPDB 444 e-125 5LP7-H nrPDB 443 e-125 4WYS-A nrPDB 443 e-125 2IBU-A nrPDB 440 e-124 5CBQ-A nrPDB 429 e-120 1WDK-C nrPDB 429 e-120 5XYJ-B nrPDB 427 e-120 3GOA-A nrPDB 424 e-119 2C7Y-A nrPDB 423 e-119 2IIK-A nrPDB 422 e-118 2WUA-A nrPDB 416 e-117 6BJA-A nrPDB 413 e-116 6BJB-A nrPDB 409 e-114 1PXT-A nrPDB 395 e-110 3SVK-A nrPDB 389 e-108 4B3J-C nrPDB 382 e-106 5ZQZ-B nrPDB 379 e-105 4UBW-A nrPDB 368 e-102 6HRV-A nrPDB 254 7e-68 6ESQ-A nrPDB 250 7e-67 5M3K-C nrPDB 224 7e-59 4BI9-A nrPDB 162 2e-40 Sequences not found previously or not previously below threshold: 5LNQ-A nrPDB 149 2e-36 4YZO-A nrPDB 113 2e-25 4U4E-A nrPDB 77 2e-14 5AB6-A nrPDB 52 4e-07 3O04-A nrPDB 51 8e-07 1J3N-A nrPDB 50 1e-06 4EWP-A nrPDB 49 3e-06 4QAV-A nrPDB 48 5e-06 4R8E-A nrPDB 48 5e-06 5W2O-A nrPDB 46 4e-05 4DFE-A nrPDB 46 4e-05 6QSP-A nrPDB 45 5e-05 4X0O-A nrPDB 44 9e-05 1OXH-A nrPDB 44 1e-04 2GP6-A nrPDB 44 1e-04 3E60-A nrPDB 44 1e-04 4YUC-A nrPDB 43 2e-04 4JRH-A nrPDB 43 2e-04 4JPF-A nrPDB 43 2e-04 3KZU-A nrPDB 43 3e-04 5BY7-A nrPDB 43 3e-04 4V2P-A nrPDB 42 4e-04 1MZJ-A nrPDB 42 4e-04 5BQS-A nrPDB 42 4e-04 4LS7-A nrPDB 42 4e-04 4DDO-A nrPDB 42 4e-04 4NHD-A nrPDB 42 6e-04 2EBD-A nrPDB 42 7e-04 2GQD-A nrPDB 41 8e-04 3IL7-A nrPDB 41 8e-04 2IX4-A nrPDB 40 0.003 6ESQ-I nrPDB 39 0.003 4JGA-A nrPDB 39 0.003 5ENY-A nrPDB 39 0.003 2AJ9-A nrPDB 38 0.006 3LM6-A nrPDB 38 0.007 3GWE-A nrPDB 38 0.007 5YO9-A nrPDB 38 0.008 2IWZ-A nrPDB 37 0.012 3IL4-A nrPDB 37 0.017 4RYB-A nrPDB 36 0.030 4EFI-A nrPDB 36 0.037 3HO9-A nrPDB 35 0.044 1UB7-A nrPDB 35 0.045 3H76-A nrPDB 35 0.068 1TQY-A nrPDB 35 0.083 4Z87-A nrPDB 33 0.17 1E5M-A nrPDB 33 0.18 6ET0-A nrPDB 33 0.19 4XOX-A nrPDB 33 0.19 4JD3-A nrPDB 33 0.19 4OQJ-A nrPDB 33 0.26 2BZ4-A nrPDB 33 0.30 4YLT-A nrPDB 32 0.37 6G2J-R nrPDB 32 0.48 5XTD-T nrPDB 32 0.66 5GW4-d nrPDB 31 0.81 4HA6-A nrPDB 31 0.95 5LBT-A nrPDB 31 0.97 1TQY-B nrPDB 31 1.2 3OYT-A nrPDB 31 1.2 5GUP-F nrPDB 30 1.5 2P1R-A nrPDB 30 1.5 5O31-R nrPDB 30 1.6 3IL3-A nrPDB 30 1.6 3OA3-A nrPDB 30 1.6 5BNS-A nrPDB 30 1.7 3VEW-A nrPDB 30 2.3 1PV9-A nrPDB 30 2.8 4ANI-C nrPDB 29 4.5 6ET3-B nrPDB 29 4.6 4ZEF-A nrPDB 29 4.7 4XTI-A nrPDB 29 4.8 1C5K-A nrPDB 28 4.9 5VXG-A nrPDB 28 5.6 3APY-A nrPDB 28 5.9 6EMK-G nrPDB 28 6.2 1W27-A nrPDB 28 6.4 3U0E-A nrPDB 28 6.6 2IVO-A nrPDB 28 8.0 2D0P-A nrPDB 28 8.0 3ZLH-A nrPDB 28 8.5 5MB9-A nrPDB 28 9.8 >4C2K-A nrPDB Length = 417 Score = 519 bits (1338), Expect = e-148, Method: Composition-based stats. Identities = 397/397 (100%), Positives = 397/397 (100%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL Sbjct: 21 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 80 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE Sbjct: 81 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 140 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD Sbjct: 141 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 200 Query: 181 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 240 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK Sbjct: 201 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 260 Query: 241 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 300 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI Sbjct: 261 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 320 Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 360 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR Sbjct: 321 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSR 380 Query: 361 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA 397 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA Sbjct: 381 ITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQSTA 417 >4N44-A nrPDB Length = 400 Score = 508 bits (1308), Expect = e-144, Method: Composition-based stats. Identities = 176/391 (45%), Positives = 254/391 (64%), Gaps = 1/391 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 ++ V + +A RT G+YG LKD A DL A K A+ + PE V+ VI+GNVLQ+ Sbjct: 1 MKEVVIASAVRTAIGSYGKSLKDVPAVDLGATAIKEAVKKAGIKPEDVNEVILGNVLQAG 60 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 AR + G+P E PA+TIN++CGSG +++ Q I +A+V++ GG E+MS Sbjct: 61 -LGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGMENMS 119 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 +APY N R+G ++G+ +++ + L D M +TAEN+A + ISREE D++A Sbjct: 120 RAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQDEFA 179 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 L SQ++ + A +G F DE+ P+ +K +KG+ + DEH R +T+E L KL P FKKDG Sbjct: 180 LASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFKKDG 239 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 TVTAGNASG+ D A ++I S + K+ PLA+IV Y +G DP+IMG GP A A Sbjct: 240 TVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYATKAA 299 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 ++KAG ++ ++DL+E NEAFA Q LAV + L D++K NVNGGAIALGHP+G SG+RI Sbjct: 300 IEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGARILV 359 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 LVH +++R K + + CIGGGQG A++++ Sbjct: 360 TLVHAMQKRDAKKGLATLCIGGGQGTAILLE 390 >4E1L-A nrPDB Length = 395 Score = 499 bits (1286), Expect = e-142, Method: Composition-based stats. Identities = 179/392 (45%), Positives = 256/392 (65%), Gaps = 2/392 (0%) Query: 3 LLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQS 62 ++ V +V+A RTP G++GG+ K+ +A L A K A+S ++ +D VI+GNVLQ+ Sbjct: 3 AMKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLNLSEIDEVIIGNVLQT 62 Query: 63 SSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM 122 +AR + + GIP P+ T+N+LCGSG +S+ Q I E +VV+ GGTE+M Sbjct: 63 G-LGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTENM 121 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKY 182 SQAPY V RFG+K+G+ ++ L L D Q M +TAEN+A K + +RE DK Sbjct: 122 SQAPYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQDKL 181 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGK-QTMQVDEHARPQTTLEQLQKLPPVFKK 241 AL+SQ + + A F +E+ P++V ++GK +T+ DE+ + T E L KL P FKK Sbjct: 182 ALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPAFKK 241 Query: 242 DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAIS 301 DGTVTAGNASG+ DGA +I+ S+ + PLA+I Y +G +P +MG GP+PA Sbjct: 242 DGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPIPATR 301 Query: 302 GALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRI 361 ALKKAGLS+ D+DL+E NEAFA Q LAV+ L +D SK NVNGGAIALGHP+G SG+RI Sbjct: 302 KALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGASGARI 361 Query: 362 TAHLVHELRRRGGKYAVGSACIGGGQGIAVII 393 L++E+++R + + + CIGGGQGI++++ Sbjct: 362 LVTLIYEMQKRKVETGLATLCIGGGQGISMVV 393 >4DD5-A nrPDB Length = 396 Score = 488 bits (1256), Expect = e-138, Method: Composition-based stats. Identities = 169/391 (43%), Positives = 256/391 (65%), Gaps = 1/391 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R V + +A RT G++GG K +A +L AAK A+ ++P+ +D ++G VL + Sbjct: 6 MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTAG 65 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 +AR + L GIP E PA+TIN +CGSG +S+ Q I + +A+++L GG E+MS Sbjct: 66 -LGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMS 124 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 +PY V + R+G ++G ++ + L+D M +TAEN+A + I+REE D+ A Sbjct: 125 MSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELA 184 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 L SQ + + A G F++E+ P+ +K +KG + DE+ +P TT+E+L KL P FKKDG Sbjct: 185 LASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGTTMEKLAKLRPAFKKDG 244 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 TVTAGNASG+ DGA +++ +++ ++ PLA IV Y +G DP IMG GPVPA A Sbjct: 245 TVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVPATKKA 304 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 L+ A ++++D+DLVE NEAFA Q +AV R L++D++K NVNGGAIA+GHP+G SG+RI Sbjct: 305 LEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSGARILT 364 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 L++E++RR K + + CIGGG G +I++ Sbjct: 365 TLLYEMKRRDAKTGLATLCIGGGMGTTLIVK 395 >3SS6-A nrPDB Length = 394 Score = 484 bits (1247), Expect = e-137, Method: Composition-based stats. Identities = 175/393 (44%), Positives = 251/393 (63%), Gaps = 2/393 (0%) Query: 3 LLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQS 62 + V + AA R+P G +GG LK+ T +L+ + A+ G V P VD VI+G+ +Q Sbjct: 3 AMHNVVITAAVRSPIGTFGGALKNVTPVELAVPVLQEAVKRGGVEPHEVDEVILGHCIQR 62 Query: 63 SSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM 122 + +A AR L G P TI R C SG Q+I++ +I + +EVV+ GG E+M Sbjct: 63 TDEA-NTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVEAM 121 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKY 182 S +PY ++ R+G +L ++ D++W L D + M TAENL +++I+REE D+ Sbjct: 122 SSSPYALKQHRWGQRLQHG-EIRDTVWEVLEDPIHHIMMGETAENLVEQYEITREEQDEV 180 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 242 AL+S A ++GYF+D++ PI +K ++ + DEH R T E+L L P F+KD Sbjct: 181 ALRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRKD 240 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 G+VTAGNASG+ DG+ +++ SE+ K+ PLARIVGY V+G DP IMGIGP PAI Sbjct: 241 GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAIRK 300 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 L+K SL+D DL+E+NEAFA QYLAVE+ LDLD K NVNG + LGHP+G +G+RIT Sbjct: 301 GLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTGARIT 360 Query: 363 AHLVHELRRRGGKYAVGSACIGGGQGIAVIIQS 395 L+HEL+RRG + + S C+GGG G+A+ I++ Sbjct: 361 VSLIHELKRRGLEKGIASLCVGGGIGVALFIEA 393 >1NL7-A nrPDB Length = 392 Score = 465 bits (1197), Expect = e-131, Method: Composition-based stats. Identities = 163/389 (41%), Positives = 236/389 (60%), Gaps = 2/389 (0%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 + + +A RT G++ G + A +L A L V+ V+ VI+G VL + + Sbjct: 5 IVIASAARTAVGSFNGAFANTPAHELGATVISAVLERAGVAAGEVNEVILGQVLPAG-EG 63 Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 AR ++ G+P+E A +N+LCGSG +++ G Q+I +A +++ GG ESMS AP Sbjct: 64 QNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESMSMAP 123 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQS 186 +C ++R G K+G ++ + LTD M TAEN+A + ++SR+E D +A+ S Sbjct: 124 HC-AHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFAVAS 182 Query: 187 QQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVT 246 Q + +AA G F DE+ P VK +KG T+ DE+ R TL+ + KL P F K+GTVT Sbjct: 183 QNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKEGTVT 242 Query: 247 AGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKK 306 AGNASG+ DGA A ++ SE + PL RIV + G DP +MG GP+PA AL++ Sbjct: 243 AGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRKALER 302 Query: 307 AGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLV 366 AG + D+DLVE NEAFA Q AV + L D S NVNGGAIA+GHP+G SG+RI L+ Sbjct: 303 AGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARILNTLL 362 Query: 367 HELRRRGGKYAVGSACIGGGQGIAVIIQS 395 E++RRG + + + CIGGG G+A+ I+S Sbjct: 363 FEMKRRGARKGLATLCIGGGMGVAMCIES 391 >1ULQ-A nrPDB Length = 401 Score = 463 bits (1191), Expect = e-131, Method: Composition-based stats. Identities = 171/398 (42%), Positives = 231/398 (58%), Gaps = 7/398 (1%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 + ++V A RTP G +GG L DL A + V E V+ V G Q+ Sbjct: 1 MPEAWIVEAVRTPIGKHGGALASVRPDDLLAHALSVLVDRSGVPKEEVEDVYAGCANQAG 60 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 D +AR L G P E T+NRLCGSG +++ + I E +V + G ESMS Sbjct: 61 EDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVESMS 120 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLP-----MAMTAENLAVKHKISREE 178 +APY V G G+ + + +L + +Q M TAENLA + I REE Sbjct: 121 RAPYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIRREE 180 Query: 179 CDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV 238 D++AL S Q+ A + G F DE+ P+ VK K + ++ DE R T+LE+L L PV Sbjct: 181 QDRFALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDTSLEKLAALRPV 240 Query: 239 FKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 298 F++ GTVTAGN+S + DGA AV++ S+D K H PLAR+ V+G P IMGIGPVP Sbjct: 241 FREGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGIGPVP 300 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERS--LDLDISKTNVNGGAIALGHPLGG 356 A AL++AGLS D+ L+E+NEAFA Q LAV R L ++ + N NGGAIALGHPLG Sbjct: 301 ATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGHPLGA 360 Query: 357 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 SG+RI LVHE+RRR ++ + + CIG GQGIAV+++ Sbjct: 361 SGARILTTLVHEMRRRKVQFGLATMCIGVGQGIAVVVE 398 >6BN2-A nrPDB Length = 401 Score = 461 bits (1187), Expect = e-130, Method: Composition-based stats. Identities = 146/393 (37%), Positives = 223/393 (56%), Gaps = 3/393 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 ++ VF+V+A RTP G++ G L AT L A K AL ++P + V MGNVLQ+ Sbjct: 9 MKEVFIVSAVRTPMGSFMGSLSGVPATQLGAVAIKGALDKINLNPAEIQDVYMGNVLQAG 68 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + A+ L G+P TP +N++C SG ++++ Q + + E ++ GG E+MS Sbjct: 69 -EGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGMENMS 127 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 Q P+ + R G KLG + L LTD + + M AE A ++ I+REE D +A Sbjct: 128 QVPHYIDG-RNGVKLGDIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNITREEQDAFA 186 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKK-D 242 +QS +R A G F +E+ P+ + +KG+ + ++ +++ LP VF+K + Sbjct: 187 IQSYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNVKFDRIPTLPTVFQKEN 246 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 GTVTA NAS + DGA A+++ S++ ++ PLA+IV Y + P P A+ Sbjct: 247 GTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEWFTTAPAKALPI 306 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 AL KA L++ D+D E NEAF+ LA + L LD +K NVNGGA+ALGHPLG SGSRI Sbjct: 307 ALAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALGHPLGSSGSRII 366 Query: 363 AHLVHELRRRGGKYAVGSACIGGGQGIAVIIQS 395 L++ L++ KY + C GGG A++I++ Sbjct: 367 VTLINVLKQNNAKYGAAAICNGGGGASAIVIEN 399 >1WL4-A nrPDB Length = 397 Score = 461 bits (1186), Expect = e-130, Method: Composition-based stats. Identities = 166/390 (42%), Positives = 228/390 (58%), Gaps = 4/390 (1%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 V +V+A RT G++ G L DL K L V+PE V VI G+VL + Sbjct: 8 VVIVSAARTIIGSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGC-G 66 Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 R + GIP PA + +CGSG +++ Q I + ++ +V+ GG E+MS+AP Sbjct: 67 QNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAP 126 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQS 186 + + +R G K+G + L LTD M +TAEN+A K ++SRE+ DK A+ S Sbjct: 127 H-LAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDKVAVLS 185 Query: 187 QQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGT-- 244 Q R + A AG+F+ E+ P+ V T+KG ++ DE R + +E + KL P F DGT Sbjct: 186 QNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGT 245 Query: 245 VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGAL 304 VT NASG+ DGA AV++ + K TPLARIV + G +PSIMGIGP+PAI A+ Sbjct: 246 VTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAV 305 Query: 305 KKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAH 364 KAG SL+D+D+ E+NEAFA A+ + L L+ K N+ GGAIALGHPLG SG RI Sbjct: 306 TKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVT 365 Query: 365 LVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 L+H L R G V + CIGGG GIA+ +Q Sbjct: 366 LLHTLERMGRSRGVAALCIGGGMGIAMCVQ 395 >4O9A-A nrPDB Length = 398 Score = 456 bits (1173), Expect = e-129, Method: Composition-based stats. Identities = 167/390 (42%), Positives = 238/390 (61%), Gaps = 2/390 (0%) Query: 6 GVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 V +V+A RT G +GG L A +L KAAL V PE V VIMG VL + S Sbjct: 8 DVVIVSAARTAVGKFGGSLAKIPAPELGAVVIKAALERAGVKPEQVSEVIMGQVLTAGS- 66 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 AR ++ G+P PA+TIN++ GSG ++++ I +AE+V+ GG E+MS A Sbjct: 67 GQNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQENMSAA 126 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 P+ + R G ++G ++ + L D + Q M +TAEN+A ++ I+RE D++A+ Sbjct: 127 PHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDEFAVG 186 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKTKKGKQT-MQVDEHARPQTTLEQLQKLPPVFKKDGT 244 SQ + +AA AG F++E+ P+ + +KG + DE R TL+ + L P F K GT Sbjct: 187 SQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAFDKAGT 246 Query: 245 VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGAL 304 VTA NASG+ DGA AV++ S K+ TPLA I Y +G DP +MG+GPVPA AL Sbjct: 247 VTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVPASKRAL 306 Query: 305 KKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAH 364 +A + +D+DL+E+NEAFA Q LAV + + D SK NVNGGAIA+GHP+G SG RI Sbjct: 307 SRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVT 366 Query: 365 LVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 L+HE++RR K + S CIGGG G+A+ ++ Sbjct: 367 LLHEMKRRDAKKGLASLCIGGGMGVALAVE 396 >4NZS-A nrPDB Length = 399 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 178/391 (45%), Positives = 247/391 (63%), Gaps = 2/391 (0%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 R V VV+ RT G +GG LKD +L + AL+ +VS + V V+ GNV+Q+ Sbjct: 8 REVVVVSGVRTAIGTFGGSLKDVAPAELGALVVREALARAQVSGDDVGHVVFGNVIQTEP 67 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 +YL R + G+ PALT+NRLCGSG Q+IV+ Q I + + +V + GG ESMS+ Sbjct: 68 RDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGAESMSR 127 Query: 125 APYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 APY R+G ++G D L D + +L D ++ M +TAEN+A ++ ISR + D+ AL Sbjct: 128 APYLAPAARWGARMG-DAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQDEAAL 186 Query: 185 QSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKK-DG 243 +S +R AA AGYF D++ P+ K +KG T DEH R T++ + KL PVF K +G Sbjct: 187 ESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMTKLRPVFVKENG 246 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGA 303 TVTAGNASG+ D A AV++ ++ PLAR+V Y +G DP MGIGPVPA A Sbjct: 247 TVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPATKIA 306 Query: 304 LKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITA 363 L++AGL + D+D++E NEAFA Q AV ++L LD +K N NG I+LGHP+G +G+ IT Sbjct: 307 LERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGALITV 366 Query: 364 HLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 +HEL R G+YA+ + CIGGGQGIA I + Sbjct: 367 KALHELNRVQGRYALVTMCIGGGQGIAAIFE 397 >6ARG-A nrPDB Length = 399 Score = 444 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 150/397 (37%), Positives = 228/397 (57%), Gaps = 4/397 (1%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAG-KVSPETVDSVIMGNV 59 M+ L V++V++ RTP G++ G L TA L A KAAL+ + P V V GNV Sbjct: 2 MSSLPAVYIVSSARTPVGSFLGSLSSLTAPQLGAHAIKAALAKVDGLKPSDVQEVFFGNV 61 Query: 60 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 119 + S++ AR L G+ + T T+N++C SG ++I+ G Q I A+VV+ GGT Sbjct: 62 I-SANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGT 120 Query: 120 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 ESMS AP+ + N+R G K G ++ + LTD Q M + AE A H SRE+ Sbjct: 121 ESMSNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQ 180 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARP-QTTLEQLQKLPPV 238 D+YA+++ ++ +AA AG F++E+API++ +GK + V + P E+L+ + P Sbjct: 181 DEYAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPA 240 Query: 239 FKK-DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPV 297 F GTVTA N+S + DGA AV++ SE +K+ N P+A+I+G+ + PS P Sbjct: 241 FIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPA 300 Query: 298 PAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGS 357 AI ALK AG+ +D E+NEAF+ LA + L + K N++GGA+A+GHP+G S Sbjct: 301 LAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGAS 360 Query: 358 GSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 G+RI L+ L+ + GK C GGG A++++ Sbjct: 361 GARILTTLLGVLKAKKGKLGCAGICNGGGGASALVVE 397 >5LP7-H nrPDB Length = 393 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 161/392 (41%), Positives = 235/392 (59%), Gaps = 2/392 (0%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R +V+A RTPFG +GG+LK+ A +L K AL VS + V+ +MG V+Q+ Sbjct: 1 MRKTVIVSAARTPFGKFGGVLKEVKAAELGGIVMKEALQQAGVSGDDVEGNVMGMVVQAG 60 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 S I +R G+P P+ T+N++C SG +++ Q I ++A++++ GG ESMS Sbjct: 61 SGQI-PSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMS 119 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 PY V R+G ++G + ++ LT ++ MA+ A ++ ISR E D++A Sbjct: 120 NIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEWA 179 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQ-TMQVDEHARPQTTLEQLQKLPPVFKKD 242 L+S R A D G F DE+ P+ +KGK + DE R T+L+QL KL P++ D Sbjct: 180 LRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDTSLDQLAKLAPIYASD 239 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 G++TAGNA GV DGAGA ++ SE+ + PLA I+G+ +G + P AI+ Sbjct: 240 GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGFAINK 299 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 LKK GL+++D+DL EVNEAFA L E+ + D+ K NVNGGAIALGHP+G SG+RI Sbjct: 300 LLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASGARIL 359 Query: 363 AHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 LV+EL+RRGG V + C G QG AV++Q Sbjct: 360 MTLVYELKRRGGGLGVAAICSGAAQGDAVLVQ 391 >4WYS-A nrPDB Length = 405 Score = 443 bits (1139), Expect = e-125, Method: Composition-based stats. Identities = 170/395 (43%), Positives = 234/395 (59%), Gaps = 2/395 (0%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 M ++ +V+A RT G++ G L +A DL KAA+ K+ + VD VIMGNVL Sbjct: 1 MGAMKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVL 60 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 Q+ AR L+ G+ + T+N++CGSG +S+ Q I +A+ ++ GG E Sbjct: 61 QAG-LGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGME 119 Query: 121 SMSQAPYCVRN-VRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 +MS APY + R G +LG + L L M +TAEN+A ++ I+RE Sbjct: 120 NMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQ 179 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF 239 D+ AL SQ++ AA ++G F E+ P+ V T+K DE + +T E L L P F Sbjct: 180 DELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAF 239 Query: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 K GTVTAGNASG+ DGA A++I E A TPLARI Y G P++MG+GPVPA Sbjct: 240 DKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPA 299 Query: 300 ISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 AL+ AGL L D+DL+E NEAFA Q+LAV ++L D K NVNGGAIALGHP+G SG+ Sbjct: 300 TQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGA 359 Query: 360 RITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 RI L+H ++ R + + CIGGGQGIA++I+ Sbjct: 360 RILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIE 394 >2IBU-A nrPDB Length = 395 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 154/392 (39%), Positives = 220/392 (56%), Gaps = 6/392 (1%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 L+ V +V+A RTP G++ G L AT L A + A+ + E V MGNVLQ Sbjct: 7 LKEVVIVSATRTPIGSFLGSLSLLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGG 66 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + R L G+P TP TIN++C SG ++I+ Q + +V++ GG ESMS Sbjct: 67 -EGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMS 125 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 PY + R T G + + LTD + ++ M AEN A K I+R E D YA Sbjct: 126 NVPYVMN--RGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYA 183 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKK-D 242 + S R KAA +AG F +E+ P+ V K + ++ + ++ KL VF+K + Sbjct: 184 INSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTVFQKEN 243 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 GTVTA NAS + DGA A+++ + DA K+ N TPLARIV + + +P I PV A S Sbjct: 244 GTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASM 303 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 LK GL +D+ + EVNEAF+ LA + L++D K N+NGGA++LGHP+G SG+RI Sbjct: 304 VLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIV 363 Query: 363 AHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 HL H L++ G+Y + S C GGG A++IQ Sbjct: 364 GHLTHALKQ--GEYGLASICNGGGGASAMLIQ 393 >5CBQ-A nrPDB Length = 413 Score = 429 bits (1103), Expect = e-120, Method: Composition-based stats. Identities = 157/403 (38%), Positives = 231/403 (57%), Gaps = 13/403 (3%) Query: 3 LLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQS 62 +R + RTP G YGG+ + TA DL A K L ++ + V+ VI+G+ Sbjct: 8 SMRDAVICEPVRTPIGRYGGMFRSLTAVDLGVTALKGLLERTGIAADQVEDVILGHCY-P 66 Query: 63 SSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM 122 +S+A + R V L G+P P + ++R CGSG Q+++ C ++ + ++V+ GG ESM Sbjct: 67 NSEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAESM 126 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLP-----MAMTAENLAVKHKISRE 177 S + ++R+G + +++ D L T + M TAENL ++ ISR Sbjct: 127 SNVAFYSTDMRWGGAR-TGVQIHDGLARGRTTAGGKFHPVPGGMLETAENLRREYHISRT 185 Query: 178 ECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPP 237 E D+ A++S QR AA G +E+ P+ V+T+ G++T+ VDEH R TT+E L KL P Sbjct: 186 EQDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHPRADTTVEALAKLKP 245 Query: 238 VF---KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGI 294 V + TVTAGN+SG D A I+ + + + PL R+V + +G P +MGI Sbjct: 246 VLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPDLMGI 305 Query: 295 GPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDL---DISKTNVNGGAIALG 351 GPVPA AL KAGL+L D+DL+E+NEAFA Q LAV R D +TNV G I+LG Sbjct: 306 GPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSGISLG 365 Query: 352 HPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 HP+G +G R+ A L EL RR +Y + + CIGGGQG+A + + Sbjct: 366 HPVGATGGRMLATLARELHRREARYGLETMCIGGGQGLAAVFE 408 >1WDK-C nrPDB Length = 390 Score = 429 bits (1103), Expect = e-120, Method: Composition-based stats. Identities = 154/397 (38%), Positives = 209/397 (52%), Gaps = 20/397 (5%) Query: 5 RGVFVVAAKRTPFG-AYGGLLKDFTATDLSEFAAKAALSA-GKVSPETVDSVIMGNVLQS 62 R V +V RTP G + GG+ ++ A D+S L KV P V+ VI G V Q+ Sbjct: 5 RDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNSKVDPGEVEDVIWGCVNQT 64 Query: 63 SSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM 122 +AR L IP + A T++RLCGS ++ Q I +V + GG E M Sbjct: 65 LEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGGVEHM 124 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKY 182 G D SL+ + M +TAE L H ISRE+ D + Sbjct: 125 GHVSMM---------HGVDPNPHMSLYAAKASG----MMGLTAEMLGKMHGISREQQDAF 171 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKG-KQTMQVDEHARPQTTLEQLQKLPPVFK- 240 A++S Q A G F DE+ P++ + G + DE RP TTLE L L P F Sbjct: 172 AVRSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNP 231 Query: 241 KDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAI 300 K GTVTAG +S + DGA +I+ S K PLA I V+G DP+IMG GPVPA Sbjct: 232 KGGTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPAT 291 Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERS---LDLDISKTNVNGGAIALGHPLGGS 357 ALK+AGL++ D+D +E+NEAFA Q L V + LD K N++GGAIALGHP G S Sbjct: 292 QKALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCS 351 Query: 358 GSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 G+RI+ L++ +++ GG + + + CIG GQGIA + + Sbjct: 352 GARISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFE 388 >5XYJ-B nrPDB Length = 408 Score = 427 bits (1098), Expect = e-120, Method: Composition-based stats. Identities = 148/398 (37%), Positives = 224/398 (56%), Gaps = 6/398 (1%) Query: 2 ALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKV--SPETVDSVIMGNV 59 ++ + V++V+ RTP G++ G L TA +L A K AL+ + + D +I GNV Sbjct: 10 SMSQNVYIVSTARTPIGSFQGSLSSKTAVELGAVALKGALAKVPELDASKDFDEIIFGNV 69 Query: 60 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 119 L S++ AR V L G+ A T+N++ S ++I+ G Q I A+VV+ GG Sbjct: 70 L-SANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGC 128 Query: 120 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 ESM+ APY + R G K G + ++ L D + L M + AE A I+RE+ Sbjct: 129 ESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQ 188 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARP-QTTLEQLQKLPPV 238 D +A++S Q+ + + G F++E+ P+ +K +GK QV + P + +E+L+ V Sbjct: 189 DNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHVEKLRSARTV 248 Query: 239 FKK-DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPV 297 F+K +GTVTA NAS + DGA AVI+ SE +K+ N PLA I G+ + P+ P Sbjct: 249 FQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAPS 308 Query: 298 PAISGALKKAGLS-LKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGG 356 A+ ALK AG+ + +D E NEAF+ L + L LD SK NV GGA+ALGHPLG Sbjct: 309 LAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGC 368 Query: 357 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 SG+R+ L+ L++ GGK V + C GGG +++I+ Sbjct: 369 SGARVVVTLLSILQQEGGKIGVAAICNGGGGASSIVIE 406 >3GOA-A nrPDB Length = 387 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 157/398 (39%), Positives = 218/398 (54%), Gaps = 20/398 (5%) Query: 4 LRGVFVVAAKRTPFG-AYGGLLKDFTATDLSEFAAKAALSAG-KVSPETVDSVIMGNVLQ 61 + V +V A RTP G + GG ++ A DLS ++ L+ ++ T+D + G V Q Sbjct: 1 MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQ 60 Query: 62 SSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 + +AR+ L IP PA+T+NRLCGS Q++ + + I +A+V L GG E Sbjct: 61 TLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVEH 120 Query: 122 MSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDK 181 M P V F L ++ + M +TAE L+ H ISRE D+ Sbjct: 121 MGHVPM-SHGVDFHPGLSRNVAKAAGM------------MGLTAEMLSRLHGISREMQDQ 167 Query: 182 YALQSQQRWKAANDAGYFNDEMAPIEVKTKKG-KQTMQVDEHARPQTTLEQLQKLPPVFK 240 +A +S R AA +G F E+ P G + DE RP+TT+E L L P F Sbjct: 168 FAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFD 227 Query: 241 K-DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 GTVTAG +S ++DGA A+++ SE ++ P ARI V GCDPSIMG GPVPA Sbjct: 228 PVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPA 287 Query: 300 ISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD---ISKTNVNGGAIALGHPLGG 356 ALKKAGLS D+D+ E+NEAFA Q L + L L K N+NGGAIALGHPLG Sbjct: 288 SKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGC 347 Query: 357 SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 SG+RI+ L++ + R+ ++ + + CIG GQGIA + + Sbjct: 348 SGARISTTLINLMERKDAQFGLATMCIGLGQGIATVFE 385 >2C7Y-A nrPDB Length = 404 Score = 423 bits (1087), Expect = e-119, Method: Composition-based stats. Identities = 150/398 (37%), Positives = 213/398 (53%), Gaps = 20/398 (5%) Query: 6 GVFVVAAKRTPFG-AYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 V +VAA RTP + G KD DL +A + ++P V +++G VL S Sbjct: 14 DVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEKTNLNPSEVGDIVVGTVLAPGS 73 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 R G P+ T+NR C SG Q++ + I ++ + G ESM+ Sbjct: 74 QRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTT 133 Query: 125 APYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 P + + + ++ Q+ LPM +T+EN+A + +SR+E D+ A+ Sbjct: 134 NP-----------MAWEGSVNPAVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAAV 182 Query: 185 QSQQRWKAANDAGYFNDEMAPIEVK------TKKGKQTMQVDEHARPQTTLEQLQKLPPV 238 S ++ AA AG F DE+ P++ K + T+ VD+ RP TTL L KL PV Sbjct: 183 DSHRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKPV 242 Query: 239 FKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 298 FKKDGT TAGN+S V+DGAGAV++ + L + G DP+IMGIGP Sbjct: 243 FKKDGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGPAV 302 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 AI A+K AGL L D+DL E+NEAFA Q++ L LD K NVNGGA+A+GHPLG +G Sbjct: 303 AIPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGATG 362 Query: 359 SRITAHLVHELRRRG--GKYAVGSACIGGGQGIAVIIQ 394 +R A L+HE++RRG ++ V S CIG G G A + + Sbjct: 363 ARCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVFE 400 >2IIK-A nrPDB Length = 418 Score = 422 bits (1085), Expect = e-118, Method: Composition-based stats. Identities = 154/400 (38%), Positives = 209/400 (52%), Gaps = 19/400 (4%) Query: 2 ALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 A V VV +RT G G KD T +L A L + PE + + +GNVL Sbjct: 27 ASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVL 86 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 Q + AI +AR IP+ P T+NR C SG Q++ + I ++ + G E Sbjct: 87 QPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVE 145 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 SMS A G+ + L + +PM +T+EN+A + ISRE+ D Sbjct: 146 SMSLA-----------DRGNPGNITSRLMEKEKARDCLIPMGITSENVAERFGISREKQD 194 Query: 181 KYALQSQQRWKAANDAGYFNDEMAPIEV-----KTKKGKQTMQVDEHARPQTTLEQLQKL 235 +AL SQQ+ A G F E+ P+ K K T+ DE RP TT+E L KL Sbjct: 195 TFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKL 254 Query: 236 PPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIG 295 P FKKDG+ TAGN+S V+DGA A+++A ++ L + Y V G P IMGIG Sbjct: 255 KPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIG 314 Query: 296 PVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLG 355 P AI AL+KAGL++ D+D+ E+NEAFA Q L L K N GGA+ALGHPLG Sbjct: 315 PAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLG 374 Query: 356 GSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGIAVIIQ 394 +G+R L++EL+RRG + Y V S CIG G G A + + Sbjct: 375 CTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 414 >2WUA-A nrPDB Length = 440 Score = 416 bits (1070), Expect = e-117, Method: Composition-based stats. Identities = 147/398 (36%), Positives = 215/398 (54%), Gaps = 20/398 (5%) Query: 6 GVFVVAAKRTPFGA-YGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 V +VAA R+P G LKD D+ KA + ++P V +++G+VL + S Sbjct: 34 DVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEKTNINPAEVGDIVVGSVLGAGS 93 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 R G P+ P T+NR C SG Q++ + I ++ + G ESM+ Sbjct: 94 QRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGLESMTA 153 Query: 125 APYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 P + + + + Q LPM +T+EN+A K I+R+E D+ A+ Sbjct: 154 NP-----------MAWEGSVNPKVKTMAQAQDCLLPMGITSENVAQKFSITRQEQDQAAV 202 Query: 185 QSQQRWKAANDAGYFNDEMAPIEVK------TKKGKQTMQVDEHARPQTTLEQLQKLPPV 238 S ++ AA AG F DE+ PI+ K + T+ VD+ RP T+L L KL PV Sbjct: 203 GSHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGIRPGTSLADLAKLKPV 262 Query: 239 FKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 298 F+KDG+ TAG +S V+DGAGAV++ + L + G PSIMGIGP Sbjct: 263 FRKDGSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRTFAAVGVPPSIMGIGPAV 322 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 AI A+K AGL + D+DL E+NEAFA Q++ ++ L++D K NVNGGA+A+GHPLG +G Sbjct: 323 AIPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDPQKINVNGGAMAIGHPLGATG 382 Query: 359 SRITAHLVHELRRRG--GKYAVGSACIGGGQGIAVIIQ 394 +R A L+HE++RRG ++ V S CIG G G A + + Sbjct: 383 ARCVATLLHEMKRRGRDCRFGVVSMCIGTGMGAAAVFE 420 >6BJA-A nrPDB Length = 397 Score = 413 bits (1062), Expect = e-116, Method: Composition-based stats. Identities = 131/392 (33%), Positives = 212/392 (54%), Gaps = 7/392 (1%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 + V++++A RTP ++ L +A DL K A+ + ++ I+GNVL + Sbjct: 9 KDVYILSAVRTPIASFRSTLTSLSAVDLGIVVTKEAIKRSLLPSSAIEETIVGNVLSAG- 67 Query: 65 DAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 +AR + + IPK + +TIN++C S ++I+ G Q I V +V+ G+ESMS Sbjct: 68 LGQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSESMSN 127 Query: 125 APYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 AP+ V R G ++ L D PM + AE + +RE+ D YA+ Sbjct: 128 APFYVP--RGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAYAI 185 Query: 185 QSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG- 243 +S ++ + A G FN E+ P+ V K+G + + ++ + E++ L P F KDG Sbjct: 186 ESYRKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIPEKVPALHPAFLKDGS 245 Query: 244 -TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISG 302 T+TA NAS + DGA A ++AS + V++ P+A+++ Y +G +P + P A+ Sbjct: 246 GTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAVKQ 305 Query: 303 ALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRIT 362 L ++GL + + L E+NEAF+ LA + L LD + NV GGA+ALGHPLG SG+RI Sbjct: 306 LLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGARIV 365 Query: 363 AHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 LVH L+ + V + C GGG+ A++I+ Sbjct: 366 VTLVHALK--SDELGVAAICNGGGEASAILIK 395 >6BJB-A nrPDB Length = 393 Score = 409 bits (1050), Expect = e-114, Method: Composition-based stats. Identities = 143/389 (36%), Positives = 203/389 (52%), Gaps = 6/389 (1%) Query: 6 GVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 V V A RTP G++ + T L A K AL V P V +G V+ S++ Sbjct: 9 DVVFVGAARTPIGSFRSAFNNVPVTVLGREALKGALKNANVKPSLVQEAFIGVVVPSNA- 67 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 AR V L G T +N++ SG ++I + + E+V+ GG ESMS Sbjct: 68 GQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGMESMSCV 127 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 P+ + R G ++ L D + + M A+ +A + I+REE DKYA+ Sbjct: 128 PFYLP--RGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDKYAIL 185 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTV 245 S +R AA G F E+ P+EV K T++ DE + E++ KL P F +G+V Sbjct: 186 SYKRSAAAWKEGIFAKEIIPLEVTQGKKTITVEEDEE-YKKVNFEKIPKLKPAFTSEGSV 244 Query: 246 TAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALK 305 TA NAS + DGA V++ + D KKH PLAR++ Y + P GI P I LK Sbjct: 245 TAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIPKVLK 304 Query: 306 KAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHL 365 AGL +KD+DL E+NEAFA L ++L LD SK N++GGA++LGHP+G SG+RI HL Sbjct: 305 LAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARIVGHL 364 Query: 366 VHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 VH L+ G+ + C GGG +II+ Sbjct: 365 VHTLK--PGQKGCAAICNGGGGAGGMIIE 391 >1PXT-A nrPDB Length = 390 Score = 395 bits (1014), Expect = e-110, Method: Composition-based stats. Identities = 139/394 (35%), Positives = 198/394 (50%), Gaps = 20/394 (5%) Query: 6 GVFVVAAKRTPFGA-YGGLLKDFTATDLSEFAAKAAL----SAGKVSPETVDSVIMGNVL 60 V +VAA R+ G + G KD L + + ++ V GNVL Sbjct: 8 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 67 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 + A R L GIP TP + +NR C SG ++ + +I V + ++ L G E Sbjct: 68 NVGAGATE-HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 126 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 SM+ N + LG + + L + + +PM +T EN+A KISR++ D Sbjct: 127 SMTN------NYKNVNPLG--MISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQD 178 Query: 181 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 240 ++A S Q+ A + G F DE+ PI++ Q DE RP T E L + P F Sbjct: 179 EFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIRPAFI 235 Query: 241 KD-GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 KD GT TAGNAS V+DG V++A + N L R + + G P IMG+GP A Sbjct: 236 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 295 Query: 300 ISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 I L+ GL ++D+D+ E+NEAFA Q L L +D++K N GGAIALGHPLG +G+ Sbjct: 296 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 355 Query: 360 RITAHLVHELRRRGGKYAVGSACIGGGQGIAVII 393 R A ++ EL++ + V S CIG G G A I Sbjct: 356 RQVATILRELKK--DQIGVVSMCIGTGMGAAAIF 387 >3SVK-A nrPDB Length = 407 Score = 389 bits (1000), Expect = e-108, Method: Composition-based stats. Identities = 143/416 (34%), Positives = 205/416 (49%), Gaps = 37/416 (8%) Query: 2 ALLRGVFVVAAKRTPFGA-YGGLLKDFTATDLSEFAAKAALSA-GKVSPETVDSVIMGNV 59 ++ F+ A RTP G G L + +L + + +I+G V Sbjct: 4 SMSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPDLDETLISDMILGVV 63 Query: 60 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 119 +AR L G+P+ T + +NR C SG +++ Q++ ++VL GG Sbjct: 64 SPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGV 123 Query: 120 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 ESMS+ P + T ++ ++ +P + A+ +A SRE+ Sbjct: 124 ESMSRVPMGSDGGAWATDPETNYRIG------------FVPQGIGADLIATLEGFSREDV 171 Query: 180 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF 239 D YAL+SQQ+ AA GYF + P+ + + G + DEH RP TT+E L KL F Sbjct: 172 DAYALRSQQKAAAAWSGGYFAKSVVPV--RDQNGLVILDHDEHMRPDTTMEGLAKLKTAF 229 Query: 240 KKDG---------------------TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLAR 278 G T GN+SG+ DGA V++ SE A K TP AR Sbjct: 230 DGVGEMGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRAR 289 Query: 279 IVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDI 338 IV SG DP IM GP PA L +AGL++ D+DL E+NEAFA L ++ L++ Sbjct: 290 IVATATSGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPD 349 Query: 339 SKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 K NVNGGAIA+GHPLG +G+ IT +V EL RR + A+ + CIGGG G+A II+ Sbjct: 350 EKLNVNGGAIAMGHPLGATGAMITGTMVDELERRNARRALITLCIGGGMGVATIIE 405 >4B3J-C nrPDB Length = 403 Score = 382 bits (982), Expect = e-106, Method: Composition-based stats. Identities = 143/415 (34%), Positives = 200/415 (48%), Gaps = 37/415 (8%) Query: 3 LLRGVFVVAAKRTPFGA-YGGLLKDFTATDLSEFAAKAALSA-GKVSPETVDSVIMGNVL 60 + F+ A RTP G G L + L + + VI+G V Sbjct: 1 MSEEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPDLDENLISDVILGCVS 60 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 +AR L G+P + + +NR C SG +++ Q++ ++VL GG E Sbjct: 61 PVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGVE 120 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 SMS+ P G +G D + +P ++ A+ +A SRE+ D Sbjct: 121 SMSRVPMGSD----GGAMGLDPATNYDVMF--------VPQSIGADLIATIEGFSREDVD 168 Query: 181 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 240 YAL+SQQ+ A GYF + P+ + + G + DEH RP TT E L KL P F+ Sbjct: 169 AYALRSQQKAAEAWSGGYFAKSVVPV--RDQNGLLILDHDEHMRPDTTKEGLAKLKPAFE 226 Query: 241 K---------------------DGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARI 279 + T GN+SG+ DGA V+I S A K TP ARI Sbjct: 227 GLAALGGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARI 286 Query: 280 VGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDIS 339 V SG DP IM GP PA L +AGL++ D+DL E+NEAFA L ++ L++ Sbjct: 287 VATATSGADPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDE 346 Query: 340 KTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 K NVNGGAIA+GHPLG +G+ I +V EL RR + A+ + CIGGG G+A II+ Sbjct: 347 KLNVNGGAIAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIE 401 >5ZQZ-B nrPDB Length = 474 Score = 379 bits (973), Expect = e-105, Method: Composition-based stats. Identities = 143/429 (33%), Positives = 210/429 (48%), Gaps = 45/429 (10%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R V VV RTPF G KD DL+ A L V E VD +I G V+Q Sbjct: 51 IRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEV 110 Query: 64 SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + +AR L G +TPA T+ C S Q++ G I + +V++ GG E MS Sbjct: 111 KTS-NVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMS 169 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLT------------------DQHVQLPMAMTA 165 P +R+ R KL D+ S+ L+ + M +A Sbjct: 170 DVP--IRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSA 227 Query: 166 ENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARP 225 + LA +SR E D+YAL+S K A D G +D + P +V GK T+ D RP Sbjct: 228 DRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVP---GKDTVTKDNGIRP 283 Query: 226 QTTLEQLQKLPPVF-KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFV 284 ++LEQ+ KL P F K GTVTA N+S + DGA A++I +E+ + P A + + Sbjct: 284 -SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMY 342 Query: 285 SGCDPSI-MGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLD------ 337 DP + +GP A L+KAGL++ D+D E +EAF+ Q LA +++D D Sbjct: 343 VSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENY 402 Query: 338 -----------ISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGG 386 + K N GG+++LGHP G +G R+ + LR+ GG+Y + +AC GG Sbjct: 403 MGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGG 462 Query: 387 QGIAVIIQS 395 QG A+I+++ Sbjct: 463 QGHAMIVEA 471 >4UBW-A nrPDB Length = 399 Score = 368 bits (944), Expect = e-102, Method: Composition-based stats. Identities = 130/404 (32%), Positives = 197/404 (48%), Gaps = 24/404 (5%) Query: 2 ALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKV----SPETVDSVIMG 57 + +V A R+P G G L AT+L KA + + V+ VI G Sbjct: 7 GSMGYPVIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGG 66 Query: 58 NVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCG 117 V Q + ++R L G+P+ A T++ CGSG Q+ I +V + Sbjct: 67 CVTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIAC 126 Query: 118 GTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAM-TAENLAVKHKISR 176 G E+MS+ G G D L + + LP AE +A + I+R Sbjct: 127 GIEAMSRV-------GLGANAGPDRSL-----IRAQSWDIDLPNQFEAAERIAKRRGITR 174 Query: 177 EECDKYALQSQQRWKAANDAGYFNDEMAPIEVK------TKKGKQTMQVDEHARPQTTLE 230 E+ D + L+SQ+R + A G F+ E++PI+ G++ + + +TT+ Sbjct: 175 EDVDVFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLRETTMA 234 Query: 231 QLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPS 290 L +L PV + G TAG +S ++DGA AV+ E + H TP ARIV + G +P Sbjct: 235 GLGELKPVLEG-GIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPY 293 Query: 291 IMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIAL 350 GPV + + L+KAG+ + D+D+VE+NEAFA L+ R + D+ + NVNGGAIAL Sbjct: 294 YHLDGPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIAL 353 Query: 351 GHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394 GHP+G +GSR+ +HEL R A+ + C GG II+ Sbjct: 354 GHPVGCTGSRLITTALHELERTDQSLALITMCAGGALSTGTIIE 397 >6HRV-A nrPDB Length = 421 Score = 254 bits (648), Expect = 7e-68, Method: Composition-based stats. Identities = 90/423 (21%), Positives = 153/423 (36%), Gaps = 71/423 (16%) Query: 6 GVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 VFV+ T F G +D D+++ A + AL+ + + +G V S+ Sbjct: 15 RVFVIGVGMTKFEKPGA--RDIDYPDMAKEAGQRALADAGIKYSAIQQACVGYVYGDSTC 72 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 H GIP + +N C +G ++ G Q I A+ VL G E M + Sbjct: 73 GQRAIYHSLGLSGIPI----INVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEKMERG 128 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 + + + +++ + +A + RE +KY + Sbjct: 129 SLSSKYMDRTNPMDKHMEV----------MINRYGLAAVPAAPQMFGNAGREHMEKYGTK 178 Query: 186 SQQRWKAANDAGY--FNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 + K A N+ + + DE+ +LEQ+ VF+ Sbjct: 179 PEHFAKVAWKNHKHSTNNPYSQFQ------------DEY-----SLEQVIDSRKVFE--- 218 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLA-RIVG----------YFVSGCDPSIM 292 +T +DGAGA ++ASE V+++ A IV + + C + Sbjct: 219 FLTLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEENSCMKMVG 278 Query: 293 GIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISK------------ 340 A AG+ D+D++E+++ F+ L +L L Sbjct: 279 YDMTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGELIDRGDNT 338 Query: 341 ------TNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGG----GQGIA 390 N +GG I+ GHPLG +G A L +LR G V A + G G A Sbjct: 339 YGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRAEAGPRQVPGAKLALQHNIGLGGA 398 Query: 391 VII 393 V++ Sbjct: 399 VVV 401 >6ESQ-A nrPDB Length = 392 Score = 250 bits (639), Expect = 7e-67, Method: Composition-based stats. Identities = 83/420 (19%), Positives = 146/420 (34%), Gaps = 80/420 (19%) Query: 4 LRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS 63 +R V ++ +T FG L + + DL A A+ V +D++ +GN+ Sbjct: 1 MRDVAIIGYGQTKFGE----LWEDSFRDLIVEAGVKAIKDANVDGGDIDAMYIGNMSGGL 56 Query: 64 -SDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM 122 ++A + G+ P + C SG ++ + + +VVL GG E M Sbjct: 57 FVGQEHIASLIADHAGL-NPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAGGVEKM 115 Query: 123 SQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKY 182 + + + D W + AM A ++ ++ EE + Sbjct: 116 TDVEDATAAIASAS---------DQEWEAFFGATFPSLYAMMARRYMYQYGLTIEELSMW 166 Query: 183 ALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKD 242 ++ + + +TTLEQ+ PV Sbjct: 167 SVIAHENATK-------------------------NKYAQFGFKTTLEQVMNASPVADP- 200 Query: 243 GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGC------------DPS 290 +T + S V+DGA A+I+ D ++ F P I+ Y + D + Sbjct: 201 --LTLMHCSPVSDGASALIVCDADKAEE--FAPKDEII-YIKASTQASDTIALHDREDMT 255 Query: 291 IMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDL-------------- 336 + V A A K A ++ + +D+ EV++ FA L + L Sbjct: 256 TLNAAKV-ASEKAYKLAKIAPEKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVIDEGK 314 Query: 337 ------DISKTNVNGGAIALGHPLGGSGSRITAHLVHELRR-RGGKYAVGSACIGGGQGI 389 D N +GG A GH LG +G R L +L++ + K + G G Sbjct: 315 IRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQDKECKDRQATIKNGYGIAA 374 >5M3K-C nrPDB Length = 398 Score = 224 bits (570), Expect = 7e-59, Method: Composition-based stats. Identities = 88/423 (20%), Positives = 151/423 (35%), Gaps = 85/423 (20%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS 64 R V +V+A TP + + F ++ +A AL K+ P + +V G + S Sbjct: 4 RRVAIVSAAYTPKPGSSRVRQTFK--EMIVESAYKALKDAKMHPREIQAVAYGYHGEGIS 61 Query: 65 DAIYLARHVGLRVGI-PKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 + L + +GI P T T N C S S G Q + E ++VLCGG E M+ Sbjct: 62 EYGGLGPTISDALGISPAPTFMSTAN--CTSSSVSFQMGHQMVASGEYDIVLCGGFEKMT 119 Query: 124 QAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYA 183 + + +GS + E ++ ++ D +A Sbjct: 120 D------HFNYAEYIGSSTECEYDYFLGIS------------------------HTDAFA 149 Query: 184 LQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDG 243 L + + ++ AG D +A + M++ P T Q +P + Sbjct: 150 LATAEYFQKFGYAGREADVLATFG-------RQMRIYAQNTPTAT-RYGQPIPSLEVLKN 201 Query: 244 TVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGC---------DPSIMGI 294 + G+ + +G I+ +E K+ P+ + G +G +P++ Sbjct: 202 SEACGSMLAWGEASGCAILVAEHLAHKYTDKPV-FVRGCAYTGVSHYFGTRFHNPTLHHP 260 Query: 295 G------------PVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVER---------- 332 G + A KKAG++ KD+D+ +V + + +E Sbjct: 261 GLPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGAGLIQMESMGICGKGQAG 320 Query: 333 --------SLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIG 384 +LD + N +GG I GH G G L +LR V A IG Sbjct: 321 DFVLEGGIALDGQL-PLNTDGGNIGRGHASGCDGILHITELFRQLRGESDN-QVKGARIG 378 Query: 385 GGQ 387 Q Sbjct: 379 VSQ 381 >4BI9-A nrPDB Length = 454 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 86/434 (19%), Positives = 152/434 (35%), Gaps = 94/434 (21%) Query: 5 RGVFVVAAKRTPFGAYGGLL------------KDFTATDLSEFAAKAALSAGKVS---PE 49 + VFVV T F G L ++ T +L + AL + Sbjct: 28 KRVFVVGGHITTFVGKGSPLFIDKKHPDFGKKENKTLEELLAESINGALQNTGLHDGRAA 87 Query: 50 TVDSVIMGNVLQSS-SDAIYLARHVGLRVGIPKET-----PALTINRLCGSGFQSIVNGC 103 VD +++GN L S +L + + PA+ + C SG ++ + Sbjct: 88 LVDKLVVGNFLGELFSSQGHLGPAAVGSLSGSNSSAFLNKPAVRVEGACASGGLAVQSAW 147 Query: 104 QEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAM 163 + + +++ L G E + ++G D Sbjct: 148 EALLAGTSQIALAVGVEVQTTVS---------ARVGGDYLAR------------------ 180 Query: 164 TAENLAVKHKISREECD-KYALQSQQRWKAANDAGYFN--DEMAPIEVKTKKGKQTMQVD 220 A +K R+ D + +R KA +AG+F D G + Sbjct: 181 -----AAHYKRQRQLDDFTFPCLFARRMKAIQEAGHFTMEDAAYVAAKAYASGNRNPLAH 235 Query: 221 EHARPQTTLE---QLQKLPPVFKKDGT----VTAGNASGVADGAGAVIIASEDAVKKHNF 273 HAR + TL+ Q P F + + + S V+DG AVI+ASE+ ++K Sbjct: 236 MHAR-KVTLDFCTQASDKNPNFLGNEIYKPFLRTTDCSQVSDGGAAVILASEEGLQKLGL 294 Query: 274 TP----LARIVGYFVS-------GCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEA 322 +P L I + D + M V A AL AG+ + + + EV++ Sbjct: 295 SPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMV-AARTALSMAGVKPEQLQVAEVHDC 353 Query: 323 FAPQYLAVERSLDLDI------------------SKTNVNGGAIALGHPLGGSGSRITAH 364 F L + +L + N GG ++ GHP+G +G + Sbjct: 354 FTIAELLMYEALGIAEYGGAGALIRSGATALDGRIPVNTGGGLLSFGHPVGATGVKQVLE 413 Query: 365 LVHELRRRGGKYAV 378 + +++ + G+Y + Sbjct: 414 VYRQMKGQCGEYQM 427 >5LNQ-A nrPDB Length = 457 Score = 149 bits (376), Expect = 2e-36, Method: Composition-based stats. Identities = 83/458 (18%), Positives = 156/458 (34%), Gaps = 99/458 (21%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLL------------KDFTATDLSEFAAKAALSAGKVSP 48 + VF+V TPF G L K+ T ++ + + +S Sbjct: 25 LQAASRVFIVGGHITPFVGKGSPLFIDKKHPDFGKKKNMTLEEILATTVQGTMEHSGLSG 84 Query: 49 ET--VDSVIMGNVLQ---SSSDAIYLARHVGLRVGIPKET------PALTINRLCGSGFQ 97 VD V++GN L SS + A L G PA+ + SG Sbjct: 85 REGIVDQVVVGNFLGELFSSQGHLGPAAIGSLTYGQAGSKNPLMYKPAMRVEGAAASGGL 144 Query: 98 SIVNGCQEICVKEAEVVLCGGTESMSQAPYCV--RNVRFGTKLGSDIKLEDSLWVSLTDQ 155 ++++ + A++ L G E + A V + +L+D + L + Sbjct: 145 AVISAMNALKSGSADITLAVGVEVQTTASARVGGDYLARAADYQRQRQLDDFTFPCLFAK 204 Query: 156 HVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQ 215 ++ +A + + E+ + A ++ G + Sbjct: 205 RMKY--------IAEHNHFTMEDTARVAAKAY-----------------------ANGNK 233 Query: 216 TMQVDEHARPQTTLEQLQKLPPV---FKKDGT----VTAGNASGVADGAGAVIIASEDAV 268 H R + T EQ P F + T + + S V+DG V++A+E+ + Sbjct: 234 NPLAHMHTR-KLTFEQCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANEEGL 292 Query: 269 KKHNFTPLA-RIVGYFVSGCDPSIMGIGP---------VPAISGALKKAGLSLKDMDLVE 318 +K +P R+V C S + P A AL A + D+++ E Sbjct: 293 RKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLNVAE 352 Query: 319 VNEAFAPQYLAVERSLDLDI------------------SKTNVNGGAIALGHPLGGSGSR 360 V++ F + + +L + N GG ++ GHP+G +G + Sbjct: 353 VHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPVGATGIK 412 Query: 361 ITAHLVHELRRRGGKYAV-------GSACIGGGQGIAV 391 + +++ + Y + + +GG AV Sbjct: 413 QIMEVYRQMKGQCEAYQMKKIPALGATLNMGGDDKTAV 450 >4YZO-A nrPDB Length = 373 Score = 113 bits (282), Expect = 2e-25, Method: Composition-based stats. Identities = 81/410 (19%), Positives = 144/410 (35%), Gaps = 79/410 (19%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSS-SD 65 V +V T FG + DL + + L +D VI+ N + Sbjct: 2 VAIVDVGITKFGK-----RKENIFDLVKEVTEKLLK------YDIDYVIVSNSYSGEFNQ 50 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 L+ + + + P+L ++ GSG +I+ + KEA VL G E MS+ Sbjct: 51 TSGLSSLITTYLNLDY-VPSLRVDNTSGSGGSAILVAKSLLESKEANTVLVVGVEKMSE- 108 Query: 126 PYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQ 185 + R TK+ S + + SL +++A K RE + A++ Sbjct: 109 ----KKTREVTKIISSLLPFEERIASL-----PSLASISAIEYMRKFNAPRESIAQVAVK 159 Query: 186 SQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTV 245 + +N + P H + + TLE++ P + + + Sbjct: 160 NH-----------YNGSLNPFA--------------HIQKRVTLEEVLNSPVISEP---L 191 Query: 246 TAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGP--VP 298 + ++DGA AV++ + + P+ I G S + P V Sbjct: 192 RLYEYTPISDGAAAVVMVRNEDALSYTSKPV-YIKGIGSSNYTAYVSEKEDFVTLPAVVE 250 Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDL-----------------DIS-K 340 A A KKA ++ +D E+++ + + L D Sbjct: 251 ASRKAFKKA--KVERIDFAELHDMATILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEIP 308 Query: 341 TNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIA 390 N +GG + GHP+G SG ++R G V +A +G +A Sbjct: 309 INPSGGLNSKGHPIGASGVAQAVEAFSQIRNEAGNRQVKNARVGLSLSMA 358 >4U4E-A nrPDB Length = 383 Score = 76.6 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 69/386 (17%), Positives = 119/386 (30%), Gaps = 80/386 (20%) Query: 22 GLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGI-P 80 G + D A L AA AL ++ VD ++ + +GI P Sbjct: 20 GKVPDKPAIALHAEAALNALEEAGLTLRDVDGLLTAGISPLELGE---------YLGIEP 70 Query: 81 KETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGS 140 T + S + + I V L ES R + Sbjct: 71 SYTDGTAVGG--SSFVIHLAHAAAAIVTGRCSVALITHGES----------GRSRVGMPP 118 Query: 141 DIKLEDSLWVSLTDQH-VQLPMAMTAENLAV---KHKISREECDKYALQSQQRWKAANDA 196 + DSL D + + P+ A + ++ ++E+ + A+ + ++W N Sbjct: 119 RVPAPDSLRGQFEDPYGLPTPVGAYALACSRHMAEYGTTKEQLAEIAVAT-RKWAMLNPK 177 Query: 197 GYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADG 256 Y D + T+E + P+ + + V D Sbjct: 178 AYMRDPI------------------------TIEDVLNSRPIVWPFNLL---DCCLVTDA 210 Query: 257 AGAVIIASEDAVKKHNFTPLARIVGYFVS------GCDPSIMGIGPVPAISGALKKAGLS 310 GA ++ S + + P+A I+G S PS+ + A K AG++ Sbjct: 211 GGACVVTSIERARDLRQHPVA-ILGVGESHDHSIISQMPSLTSFAARRSGQAAFKMAGVT 269 Query: 311 LKDMDLVEVNEAFAPQYLAVERSLDLDIS------------------KTNVNGGAIALGH 352 D+DL + ++F L L N NGG ++ H Sbjct: 270 HDDIDLAMIYDSFTYTVLLSLEDLGFCAKGEGGAFVSGQRTAPGGDFPMNTNGGGLSYTH 329 Query: 353 PLGGSGSRITAHLVHELRRRGGKYAV 378 P G G V +LR + Sbjct: 330 P-GMYGMFAIIEAVRQLRHDYADQGI 354 >5AB6-A nrPDB Length = 425 Score = 51.9 bits (123), Expect = 4e-07, Method: Composition-based stats. Identities = 56/423 (13%), Positives = 110/423 (26%), Gaps = 98/423 (23%) Query: 7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA 66 V +V RT G +L+ A K AL + + ++I V +S Sbjct: 22 VRIVGVGRTGIGKLHKS-----VDELAASALKCALVDANMKQCDLQALIA--VPSLASPQ 74 Query: 67 IYLARHVGLRVGIPKETP---ALTINRLCGSGFQSIVNGCQEICVKEAE---VVLCGGTE 120 A H+ G+ T++ ++ + + AE V+ Sbjct: 75 FMQAHHIATVAGLFPTKGKFIVRTVDTGGAGPITALGMAVDLVRTRCAETVAVIAADAVL 134 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 SM + R+ + G + ++ ++ + RE+ Sbjct: 135 SMGSGAFAERSNASLRRSGLPEPCIPHGYDRYAQWYMS------------RYGLKREQLA 182 Query: 181 KYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFK 240 + + + +A + TL+++ V Sbjct: 183 MVPVLMSKMAERHPEAMC-------------------------QKAYTLDEVLHSRCVAP 217 Query: 241 KDGTVTAGNASGVADGAGAVIIASEDAVKKH------------NFTPLARIVGYFVSGCD 288 + + DGA A+I++ E +H P+ V Sbjct: 218 VTNLLECARRA---DGAVALIVSGEAHYAEHFAQGKQEQRHLGGSKPIIASVAEASGPLF 274 Query: 289 PSIMGIGPVP-------AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDIS-- 339 P VP A A A L++ D+ + + F + ++ L Sbjct: 275 PPGSSDDIVPDIFSCRHAARDAFLSANLNVGDIHFFGLYDCFPICLIQAVEAVGLCPEGK 334 Query: 340 ------------------------KTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK 375 N +GG G P + +L G Sbjct: 335 GGEFMETAYNEMLNNGGVLDPSKFPINTHGGLQCFGAPWEVPAMYNITEAIAQLSEEAGD 394 Query: 376 YAV 378 + Sbjct: 395 RQL 397 >3O04-A nrPDB Length = 413 Score = 51.2 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 14/118 (11%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG VI+ + K A IVGY +G P+ G G A+ A+ A Sbjct: 231 IGEGAGIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDA 290 Query: 308 GLSLKDMDLVEV-------NEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 GL+ +D + N+ + Q + K ++ GH LG SG Sbjct: 291 GLTPDKVDYINAHGTSTPYNDEYETQAIKTV--FGEHAKKLAISSTKSMTGHTLGASG 346 >1J3N-A nrPDB Length = 408 Score = 50.4 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 30/171 (17%), Positives = 58/171 (33%), Gaps = 32/171 (18%) Query: 24 LKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAI-------------YLA 70 + + AA+ AL + PE +D +G ++ + + Sbjct: 66 RRLDRFVQYALIAAQLALEDAGLKPEDLDPERVGTLVGTGIGGMETWEAQSRVFLERGPN 125 Query: 71 R----------------HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVV 114 R H+ +R G P+ T+ C +G ++ + + I + EA++V Sbjct: 126 RISPFFIPMMIANMASAHIAMRYGF--TGPSSTVVTACATGADALGSALRMIQLGEADLV 183 Query: 115 LCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTA 165 L GGTE+ + P + L + + + T M A Sbjct: 184 LAGGTEA-AITPMAIGAFAVMRALSTRNEEPEKASRPFTLSRDGFVMGEGA 233 Score = 48.1 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 10/117 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG +++ + + KK A +VG+ S +P G G A++ ALK A Sbjct: 229 MGEGAGVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPHPEGKGAALAMARALKDA 288 Query: 308 GLSLKDMDLVEVNEAFA-----PQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 G++ + + + + + LA++R + V+ +GH LG +G+ Sbjct: 289 GIAPEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGA 345 >4EWP-A nrPDB Length = 350 Score = 49.2 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 22/112 (19%), Positives = 36/112 (32%), Gaps = 2/112 (1%) Query: 14 RTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHV 73 RT + T ++ AA+ AL + +D+VI+ V + A Sbjct: 47 RTGIVTRQRATAEETVPVMAVGAAREALERAGLQGSDLDAVIVSTVTFPHATPSAAALVA 106 Query: 74 GLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 P PA ++ C + + A VL G E +S Sbjct: 107 HEIGATPA--PAYDVSAACAGYCYGVAQADALVRSGTARHVLVVGVERLSDV 156 >4QAV-A nrPDB Length = 415 Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 8/114 (7%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGI---GPVPAISGALKKAGL 309 + +GAG +++ + KK A IVG+ +S I GP A++ ALK AG+ Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGI 292 Query: 310 SLKDMDLVEVNEAFAPQYLAVE-----RSLDLDISKTNVNGGAIALGHPLGGSG 358 + +D+D V + P A E R+ KT V+ GH LG +G Sbjct: 293 NPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAG 346 Score = 35.8 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 10/37 (27%), Positives = 20/37 (54%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 P+ + C +G +I N + I +A++++ GG E Sbjct: 157 PSYGMVSACTTGAHAIGNSARLIKYGDADIMVAGGAE 193 >4R8E-A nrPDB Length = 413 Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 48/117 (41%), Gaps = 10/117 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + DGAG +++ + KK A +VG+ +S P G G A+ AL+ A Sbjct: 232 LGDGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDA 291 Query: 308 GLSLKDMDLVEVNEAFA-----PQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 G++ + + + + AV+ D K V+ GH LG +G+ Sbjct: 292 GITTSQIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGA 348 Score = 36.5 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 23/40 (57%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 P+++I C SG +I + + I +A+V++ GG E S Sbjct: 156 PSISIATACTSGVHNIGHAARIIAYNDADVMVAGGAEKAS 195 >5W2O-A nrPDB Length = 439 Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 23/132 (17%) Query: 254 ADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKAG 308 + ++I +E+ K PLAR++G ++ P+ G+ A++ +L+ AG Sbjct: 263 GEAGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAG 322 Query: 309 LSLKDMDLVEVN----------EAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 LS D+D V + EA A + +++ ALGH +G G Sbjct: 323 LSPADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKS--------ALGHSIGAVG 374 Query: 359 SRITAHLVHELR 370 + + V LR Sbjct: 375 ALESVLTVLTLR 386 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 25/48 (52%) Query: 73 VGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 + + + +T C SG ++I + ++I + +A+V +CGG E Sbjct: 175 AVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE 222 >4DFE-A nrPDB Length = 333 Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 27/122 (22%), Positives = 52/122 (42%), Gaps = 7/122 (5%) Query: 6 GVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 ++V RT A D T +DL+ A++ A+ A + P+++D +I V S+ D Sbjct: 44 DEWIV--ARTGIHARYFAEPDVTTSDLAFIASQRAIEAADIDPQSIDLII---VATSTPD 98 Query: 66 AIYLARHVGL--RVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 ++ + L ++GI A + +C ++ I + L G E+ S Sbjct: 99 FVFPSTACLLQNKLGIRNHGAAFDVQAVCSGFAYAVATADSFIRSGQHRTALVIGAETFS 158 Query: 124 QA 125 + Sbjct: 159 RI 160 >6QSP-A nrPDB Length = 406 Score = 45.4 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 14/113 (12%) Query: 67 IYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 +R + + I E PA T++ C S ++I++G + I + + + GG +++S+ P Sbjct: 151 GDPSRFLARYLAI--EGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMP 208 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 179 + +SL +L + Q +T + ++RE Sbjct: 209 I------------NGFDSLESLSPTLCEPFCQDRQGITIGEASTLLLLTREPQ 249 >4X0O-A nrPDB Length = 362 Score = 44.2 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 41/110 (37%), Gaps = 4/110 (3%) Query: 14 RTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHV 73 RT + + DL+ AA+ A++ VS E +D +I+ S +A V Sbjct: 39 RTGIEQRRISHVNTS--DLATVAAQHAIACAGVSVEEIDLIIVATCSPDSLI-PNIASRV 95 Query: 74 GLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 +GIP A +N C + + + L G E +S Sbjct: 96 QQNLGIP-SAAAFDLNAACTGFLYGLETATRLMQASHYRHALVIGAERLS 144 >1OXH-A nrPDB Length = 430 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 21/130 (16%) Query: 197 GYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADG 256 G + P + + + E + F KD N + +G Sbjct: 208 GGTEASITPFAIAGFQALTALSTTEDPTRASIP---------FDKDR-----NGFVMGEG 253 Query: 257 AGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIM------GIGPVPAISGALKKAGLS 310 +G +++ S + +K T LA +VGY + CD M G G + AI AL++A +S Sbjct: 254 SGMLVLESLEHAEKRGATILAEVVGYGNT-CDAYHMTSPHPEGQGAIKAIKLALEEAEIS 312 Query: 311 LKDMDLVEVN 320 + + V + Sbjct: 313 PEQVAYVNAH 322 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 46/212 (21%), Positives = 70/212 (33%), Gaps = 27/212 (12%) Query: 85 ALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKL 144 +IN C S +I + + I +V+L GGTE+ S P+ + + T L + Sbjct: 176 CKSINTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEA-SITPFAIAGFQALTALSTTEDP 234 Query: 145 EDSLWVSLTDQHVQLPMAMTAENL-------AVKHKISR--------EECDKYALQSQ-- 187 + D+ M + L A K + CD Y + S Sbjct: 235 TRASIPFDKDR-NGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHP 293 Query: 188 --QRWKAANDAGYFNDEMAPIEVKTKKGKQTMQ-VDEHARPQTTLEQLQKLPPVFKKDGT 244 Q A E++P +V T +E + L K PV Sbjct: 294 EGQGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF 353 Query: 245 VTAGNASGVADGAGAVIIASEDAVKKHNFTPL 276 G+ G AGAV +HNF P+ Sbjct: 354 T--GHLLG---AAGAVEAIVTIEAMRHNFVPM 380 >2GP6-A nrPDB Length = 434 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 12/116 (10%) Query: 254 ADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKAG 308 +G ++I +E+ K LARI+G ++ P G AI+ A++ AG Sbjct: 257 GEGGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAG 316 Query: 309 LSLKDMDLVEVNEAFA-----PQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 L+ D+D V + + A+ +L ++ V ALGH +G G+ Sbjct: 317 LAPGDIDHVNAHATGTQVGDLAEGRAINNALGG--NRPAVYAPKSALGHSVGAVGA 370 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 23/48 (47%) Query: 73 VGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 + + + +T C SG ++I Q+I + EA+ +CGG E Sbjct: 168 AAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVE 215 >3E60-A nrPDB Length = 424 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 27/58 (46%), Gaps = 5/58 (8%) Query: 69 LARHVGLRVGIPKET-----PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 R + L G P ++ C +G +I + + I + +A+V+L GGTES Sbjct: 146 PGRLINLASGYVSIKYGLRGPNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTES 203 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 9/109 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GA V++ + KK A I+GY +SG PS G G ++ ALK+A Sbjct: 243 MGEGAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRA 302 Query: 308 GLSLKDMDLVEVNE----AFAPQYLAVERSLDLDISKTNVNGGAIALGH 352 +++ ++D + + A + AVER L + +++ ++GH Sbjct: 303 QVNVSELDYINAHGTSTMADVIELAAVERVLGYYAPQVSMSSTKSSIGH 351 >4YUC-A nrPDB Length = 335 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 6/87 (6%) Query: 21 GGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVI--MGNVLQSS-SDAIYLARHVGLRV 77 +KD TA+ + AAK A+ + E +D +I G+ Q+ + R +GL Sbjct: 50 RRWVKDETASFMGAEAAKEAVRDAGLKLEDIDLIINASGSPEQAVPDGGPLVQRELGLGR 109 Query: 78 GIPKETPALTINRLCGSGFQSIVNGCQ 104 P++T+N C S F ++ Sbjct: 110 ---SGVPSITVNASCLSFFVALDVAAN 133 >4JRH-A nrPDB Length = 417 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 38/132 (28%), Gaps = 27/132 (20%) Query: 19 AYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDA---IYLARHVGL 75 + K A AL + ++ +G + S I + Sbjct: 67 SKKDARKMDLFIQYGIAAGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQALI 126 Query: 76 RVG----IPKETPALTINRL--------------------CGSGFQSIVNGCQEICVKEA 111 G P P+ +N + C +G +I + + I +A Sbjct: 127 EKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAARMIAYGDA 186 Query: 112 EVVLCGGTESMS 123 + ++ GG E S Sbjct: 187 DAMVAGGAEKAS 198 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 5/73 (6%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + DGAG +++ + K A +VG+ +SG PS G G A+ A++ A Sbjct: 235 LGDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDA 294 Query: 308 GLSLKDMDLVEVN 320 G++ + + V + Sbjct: 295 GVTGEQIGYVNAH 307 >4JPF-A nrPDB Length = 436 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 26/117 (22%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 ++DG+GA+++ + + A +VG+ +SG P G G + AL+ A Sbjct: 254 LSDGSGALVLEELEHARARGARIYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDA 313 Query: 308 GLSLKDMDLVEVN----EAFAPQYLAVERSLDLDISKTNVNGGAIAL-GHPLGGSGS 359 GL + +D + + A +A +S+ + + ++ GH LG +G+ Sbjct: 314 GLDPRQVDYINAHGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGA 370 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 P + C +G SI + I EA+V++ GG+E Sbjct: 178 PNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSE 214 Score = 30.7 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 31/101 (30%), Gaps = 12/101 (11%) Query: 17 FGAYGGLLKDFTATDLSEFA---AKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHV 73 FG G + A K AL + P VD + N +S+ A +A Sbjct: 283 FGMSGDAFHMTAPPEDGAGAARCMKNALRDAGLDPRQVDYI---NAHGTSTPAGDIAEIA 339 Query: 74 GLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVV 114 ++ + L S +S + G E + Sbjct: 340 AVK-----SVFGEHAHALSMSSTKS-MTGHLLGAAGAVEAI 374 >3KZU-A nrPDB Length = 428 Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 50/109 (45%), Gaps = 9/109 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG V++ + A ++GY +SG P+ G G + ALK+A Sbjct: 247 MGEGAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHITAPTESGEGAQRCMVAALKRA 306 Query: 308 GLSLKDMDLVEVNE----AFAPQYLAVERSLDLDISKTNVNGGAIALGH 352 G+ ++D + + A + AVER + +K +++ ++GH Sbjct: 307 GIVPDEIDYINAHGTSTMADTIELGAVERVVGEAAAKISMSSTKSSIGH 355 Score = 41.9 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 22/38 (57%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 P ++ C +G +I + + I +A+V++ GGTES Sbjct: 170 PNHSVVTACATGTHAIGDAARLIAFGDADVMVAGGTES 207 >5BY7-A nrPDB Length = 360 Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 34/88 (38%), Gaps = 2/88 (2%) Query: 31 DLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINR 90 DL+ A AL A V+PE VD V++G A V R+GI PA + Sbjct: 83 DLAHQAGSRALDAAGVTPEEVDLVVLGTATPD-RLMPTTATVVADRLGI-DGVPAYQLQS 140 Query: 91 LCGSGFQSIVNGCQEICVKEAEVVLCGG 118 C Q++ + A L G Sbjct: 141 GCSGAVQALAVTRSLLLGGTARTALVLG 168 >4V2P-A nrPDB Length = 351 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 36/87 (41%), Gaps = 6/87 (6%) Query: 21 GGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVI--MGNVLQSS-SDAIYLARHVGLRV 77 +K TA + AAK A+ + +D +I G+ Q+ + R +GL Sbjct: 66 RRWVKGETAAFMGAEAAKEAVRDAGLQLSDIDLIISASGSPQQAVPDGGPLVQRELGLGR 125 Query: 78 GIPKETPALTINRLCGSGFQSIVNGCQ 104 TPA+T+N C S F ++ Sbjct: 126 ---SGTPAITVNASCLSFFVALEVASN 149 >1MZJ-A nrPDB Length = 339 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 19/116 (16%), Positives = 38/116 (32%), Gaps = 8/116 (6%) Query: 13 KRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD---AIYL 69 RT + D T + A++ AL V P +D V++ + ++ + Sbjct: 44 TRTGIRSRRIAEPDETIQVMGVAASRRALEHAGVDPAEIDLVVVSTMTNFVHTPPLSVAI 103 Query: 70 ARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 A +G ++ C ++ + + VL TE M+ Sbjct: 104 AHELG-----ADNAGGFDLSAACAGFCHALSIAADAVESGGSRHVLVVATERMTDV 154 Score = 27.7 bits (60), Expect = 9.9, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 279 IVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLV 317 I ++ D +I +G V A AL+ AG+ ++DLV Sbjct: 48 IRSRRIAEPDETIQVMG-VAASRRALEHAGVDPAEIDLV 85 >5BQS-A nrPDB Length = 323 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 41/102 (40%), Gaps = 4/102 (3%) Query: 25 KDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLAR-HVGLRVGIPKET 83 + + +DL+ AK ++ ++ + +D +I+ + S AR + + Sbjct: 46 RTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGA---NKA 102 Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 A + C ++ + I + L G+E++S+A Sbjct: 103 FAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKA 144 >4LS7-A nrPDB Length = 426 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 34/73 (46%), Gaps = 5/73 (6%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG +++ + IVGY +G P+ G G A+ A+K A Sbjct: 244 MGEGAGIIVLEELEHALARGAKIYGEIVGYGSTGDAYHITAPAQDGEGGARAMQEAIKDA 303 Query: 308 GLSLKDMDLVEVN 320 G++ +++D + + Sbjct: 304 GIAPEEIDYINAH 316 Score = 36.5 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 39/95 (41%), Gaps = 6/95 (6%) Query: 72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES-MSQAPYCVR 130 + + +G K + T+ C +G SI + + I +A+V++ GGTE+ +++ + Sbjct: 159 QISIALG-AKGVNSCTVT-ACATGTNSIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGF 216 Query: 131 NVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTA 165 + D K + D V M A Sbjct: 217 SANKALSTNPDPKTASRPFDKNRDGFV---MGEGA 248 Score = 28.4 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 5/22 (22%), Positives = 11/22 (50%) Query: 33 SEFAAKAALSAGKVSPETVDSV 54 A + A+ ++PE +D + Sbjct: 292 GARAMQEAIKDAGIAPEEIDYI 313 >4DDO-A nrPDB Length = 451 Score = 41.9 bits (97), Expect = 4e-04, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 17/120 (14%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGP------VPAISGALKK 306 + +GA V++ S D P+A I+GY + D M GP + A+ AL+ Sbjct: 262 MGEGAAMVVVESLDHALARGARPIAEIIGYGTTA-DAYHMTAGPDDGSGAMRAMKLALRM 320 Query: 307 AGLSLKDMDLVEVN-------EAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 ++ + +D V + +A + L + + ++ A GH LG +G+ Sbjct: 321 GDVAPEQVDYVNAHATSTPVGDAGEIEALKTVFGVGAGPA---ISSTKSATGHLLGAAGA 377 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 18/31 (58%) Query: 91 LCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 C + Q+I + + I EA+VVL GG E+ Sbjct: 192 ACAASVQAIGDAMRMIRTGEADVVLAGGAEA 222 >4NHD-A nrPDB Length = 319 Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 26/124 (20%), Positives = 50/124 (40%), Gaps = 4/124 (3%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 M ++V RT + T D++ FAA+ A++ + +D +I+ Sbjct: 28 MVETSDEWIV--ARTGIRERRIAADNETVADMAFFAAQNAINMAGIDKHDIDMIIVAT-T 84 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 +S A V ++GI K PA + C ++ Q + + VL G + Sbjct: 85 SASHTFPSAACQVQGKLGI-KGCPAFDLAAACSGFMYALSIADQHVKSGMCKHVLVIGAD 143 Query: 121 SMSQ 124 ++S+ Sbjct: 144 ALSK 147 >2EBD-A nrPDB Length = 309 Score = 41.5 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 38/210 (18%), Positives = 76/210 (36%), Gaps = 15/210 (7%) Query: 13 KRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARH 72 RT K+ T T ++ AAK AL +SPE +D +I+ + + + Sbjct: 35 TRTGIKERRIA-KEETITYMATQAAKEALREANLSPEELDLIILATLTP---QKRFPSTA 90 Query: 73 VGLRVGIPKE-TPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPY---- 127 ++ + + A I+ C ++ I +A+ VL G E +S+A Sbjct: 91 CLVQAQLKAKGVYAFDISAACSGFIYALDIADSFIKSGKAKNVLVIGAEKLSEAVDWEDR 150 Query: 128 ---CVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYAL 184 + G + + + + + + L + A+N RE K A+ Sbjct: 151 STCVLFGDGAGAVVVTRSEDKSDILATRMYAEGSLEELLHADNCGYIRMKGRE-LFKVAV 209 Query: 185 QSQQRW--KAANDAGYFNDEMAPIEVKTKK 212 +S + + AG +E++ + Sbjct: 210 RSMEEVCREVLEKAGVKPEEVSLVIPHQAN 239 Score = 29.2 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 22/44 (50%) Query: 301 SGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVN 344 L+KAG+ +++ LV ++A A+ L++ K VN Sbjct: 217 REVLEKAGVKPEEVSLVIPHQANVRIINALAEKLNIPKEKVFVN 260 >2GQD-A nrPDB Length = 437 Score = 41.1 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 10/116 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG ++I S ++ + A IVGY +G P+ G G A+ A+ A Sbjct: 255 MGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDA 314 Query: 308 GLSLKDMDLVEVNEAFAPQY-----LAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 G+ KD+ + + P A++ + V+ GH LG +G Sbjct: 315 GIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATG 370 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 43/126 (34%), Gaps = 27/126 (21%) Query: 23 LLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIY---LARHVGLRVG- 78 + T + AA+ A+ ++ + +G + S + +A + G Sbjct: 92 ARRMDRFTQYAIVAAREAVKDAQLDINENTADRIGVWIGSGIGGMETFEIAHKQLMDKGP 151 Query: 79 -------IPKETPALTINRL----------------CGSGFQSIVNGCQEICVKEAEVVL 115 +P P + ++ C +G SI + + +A+ ++ Sbjct: 152 RRVSPFFVPMLIPDMATGQVSIDLGAKGPNGATVTACATGTNSIGEAFKIVQRGDADAMI 211 Query: 116 CGGTES 121 GGTE+ Sbjct: 212 TGGTEA 217 >3IL7-A nrPDB Length = 313 Score = 41.1 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 40/129 (31%), Gaps = 26/129 (20%) Query: 14 RTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVI------------MGNVLQ 61 T D +DL+ A+ A++ + PE +D +I + N+LQ Sbjct: 36 MTGIKERHWADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQ 95 Query: 62 SSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 +A L C S++ Q + + +L G + Sbjct: 96 ERLGTGKVASMDQLAA--------------CSGFMYSMITAKQYVQSGDYHNILVVGADK 141 Query: 122 MSQAPYCVR 130 +S+ Sbjct: 142 LSKITDLTD 150 Score = 28.4 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 22/46 (47%) Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVN 344 A + ++KA L+ D+DL ++A + L + K +V+ Sbjct: 217 ASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVS 262 Score = 27.7 bits (60), Expect = 9.7, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 16/38 (42%), Gaps = 3/38 (7%) Query: 280 VGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLV 317 + D S + A A+ AG+ +D+D++ Sbjct: 42 RHWADDDQDTSDLAY---EASVKAIADAGIQPEDIDMI 76 >2IX4-A nrPDB Length = 431 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 19/31 (61%) Query: 91 LCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 C +G SI + + I +A+V++ GGTES Sbjct: 178 ACATGAHSIGDATRMIQFGDADVMVAGGTES 208 >6ESQ-I nrPDB Length = 349 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 37/107 (34%), Gaps = 6/107 (5%) Query: 25 KDFTATD-----LSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGI 79 K + D ++ AA+ A+ ++ E + +V +G+ + A Sbjct: 43 KSVPSPDEDTATIAVEAARNAVKRAGINAEKIGAVYVGSESHPYAVKPTSATVAEAIGAT 102 Query: 80 PKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAP 126 P T A + C +G I + E + G ++ AP Sbjct: 103 PDLTAA-DLEFACKAGTAGIQMCMGLVGSGLIEYGMAIGADTAQGAP 148 >4JGA-A nrPDB Length = 437 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTES 121 P T C +G +I + + I A+V++ GG E+ Sbjct: 177 PNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAEA 214 Score = 37.7 bits (86), Expect = 0.008, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 48/117 (41%), Gaps = 10/117 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GAG V++ + ++GY +G P G G A+ A+ A Sbjct: 254 MGEGAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAMLDA 313 Query: 308 GLSLKDMDLVEVNEAFA----PQYLAVERSLDLDIS-KTNVNGGAIALGHPLGGSGS 359 ++ +D + + LA + L L+ + K ++ ++GH LG +GS Sbjct: 314 TITPDMIDYINAHGTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGHLLGAAGS 370 >5ENY-A nrPDB Length = 764 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 29/213 (13%), Positives = 58/213 (27%), Gaps = 27/213 (12%) Query: 37 AKAALSAGKVSPETVDS----VI-------MGNVLQSSSDAIYLARHVGLRVG-IPK--- 81 A + T++ V G +L S A + IP Sbjct: 271 GYKAFEDAGYNARTLNEKKCGVYLGIMSNEYGVMLNRQSRANATGNSFAIAAARIPYFLN 330 Query: 82 -ETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGS 140 + PA+ I+ C S Q + KE ++ L GG + + + + Sbjct: 331 LKGPAIPIDTACSSSLVGTHLARQALINKEIDMALVGGV------SLYLTPESYMSMCEA 384 Query: 141 DIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFN 200 + D + + A L + + D A + + Sbjct: 385 GMLSPDGQCKAFDNGANGFVPGEGAGAL-----VLKRLKDAEADRDHIYGIIIGSGINQD 439 Query: 201 DEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQ 233 + I + K + ++ D + E + Sbjct: 440 GKTNGITAPSAKSQMDLERDIYETYGIHPESIS 472 >2AJ9-A nrPDB Length = 356 Score = 38.5 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 38/112 (33%), Gaps = 2/112 (1%) Query: 12 AKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLAR 71 RT D +A ++ A + ALS +S +D VI+ A Sbjct: 65 YTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIV-TTNTHFLQTPPAAP 123 Query: 72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 V +G K ++ C ++ I A +L GTE +S Sbjct: 124 MVAASLG-AKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLS 174 Score = 31.5 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 33/168 (19%), Positives = 55/168 (32%), Gaps = 28/168 (16%) Query: 247 AGNASGVADGAGAVII------------ASEDAVKKHNFTPLARIVGYFV--SGCDPSIM 292 AGN ADGA AV++ A D + + + SG P + Sbjct: 182 AGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVR 241 Query: 293 GIGPVP----------AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTN 342 GP A+ AG+ +D+ ++A + + ++L L Sbjct: 242 LEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVV 301 Query: 343 VNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIA 390 N + H S + I + L K + IG G G++ Sbjct: 302 AN----DIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLS 345 >3LM6-A nrPDB Length = 346 Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 23/115 (20%), Positives = 46/115 (40%), Gaps = 11/115 (9%) Query: 25 KDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETP 84 + L E A AL ++ + +D ++ G++L + A Y+ARH+ + P Sbjct: 51 WEMAERQLMEDAVNVALQKNNLTKDDIDLLLAGDLLNQNVTANYVARHL--------KIP 102 Query: 85 ALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLG 139 L + C + +++ + A+ L + S R R+ T+ G Sbjct: 103 FLCMFGACSTSMETVAVASALVDGGFAKRALAA---TSSHNATAERQFRYPTEYG 154 >3GWE-A nrPDB Length = 365 Score = 38.1 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 58/166 (34%), Gaps = 4/166 (2%) Query: 28 TATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALT 87 TA DL+ AA+ + G V + VD VI+ A + R+GIP AL Sbjct: 79 TAADLAYEAARKLFAQGAVGADQVDFVIL-CTQAPDYVLPTSACMLQHRLGIPTHAGALD 137 Query: 88 INRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVR---FGTKLGSDIKL 144 +N C + + A VL ++ S+ + + FG + + Sbjct: 138 VNLGCSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDKSVRTLFGDGASATAVI 197 Query: 145 EDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRW 190 + + V A NL VK + RE + + + Sbjct: 198 AEHGELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDA 243 >5YO9-A nrPDB Length = 371 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 32/86 (37%), Gaps = 3/86 (3%) Query: 31 DLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINR 90 + AAK A+ V+ E +D VI+ S+ Y A + ++ + + A +N Sbjct: 100 EWGVIAAKQAMENAGVTAEDIDVVILAC---SNMQRAYPAVAIEIQSALGIQGYAYDMNV 156 Query: 91 LCGSGFQSIVNGCQEICVKEAEVVLC 116 + + I V+L Sbjct: 157 AASAATFGLKQAADAIRSGARRVLLV 182 Score = 32.3 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 29/71 (40%), Gaps = 7/71 (9%) Query: 297 VPAISGALKKAGLSLKDMDLV-----EVNEAFAPQYLAVERSLDLD--ISKTNVNGGAIA 349 V A A++ AG++ +D+D+V + A+ + ++ +L + NV A Sbjct: 103 VIAAKQAMENAGVTAEDIDVVILACSNMQRAYPAVAIEIQSALGIQGYAYDMNVAASAAT 162 Query: 350 LGHPLGGSGSR 360 G R Sbjct: 163 FGLKQAADAIR 173 >2IWZ-A nrPDB Length = 438 Score = 37.3 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 32/209 (15%), Positives = 62/209 (29%), Gaps = 45/209 (21%) Query: 12 AKRTPFGAYGGLLKD------------FTATDLSEFAAKAALSAGKVSP-ETVDSVIMGN 58 A P G+ G + + T ++ AA+ A+ P D V G Sbjct: 68 AAYVPRGSDEGQFNEQNFVSKSDIKSMSSPTIMAIGAAELAMKDSGWHPQSEADQVATGV 127 Query: 59 VLQSSSDAIYLARHVGLRVGI-------PKETPALTINRL-------------------- 91 + + + L P P + +N Sbjct: 128 AIGMGMIPLEVVSETALNFQTKGYNKVSPFFVPKILVNMAAGQVSIRYKLKGPNHAVSTA 187 Query: 92 CGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVS 151 C +G ++ + + I +A+V++ GGT+S +P + L ++ + Sbjct: 188 CTTGAHAVGDSFRFIAHGDADVMVAGGTDS-CISPLSLAGFSRARALSTNSDPK-LACRP 245 Query: 152 LTDQHVQLPMAMTAENLA---VKHKISRE 177 + M A L +H + R Sbjct: 246 FHPKRDGFVMGEGAAVLVLEEYEHAVQRR 274 Score = 35.8 bits (81), Expect = 0.031, Method: Composition-based stats. Identities = 23/120 (19%), Positives = 53/120 (44%), Gaps = 16/120 (13%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + +GA +++ + + A ++GY +SG P G G + ++ ALK A Sbjct: 255 MGEGAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDA 314 Query: 308 GLSLKDMDLVEVN-------EAFAPQYLA-VERSLDLDISKTNVNGGAIALGHPLGGSGS 359 G+ +++ + + +A + + + + ++ ++ G A GH LG +G+ Sbjct: 315 GVQPEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKG---ATGHLLGAAGA 371 >3IL4-A nrPDB Length = 320 Score = 36.9 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 40/111 (36%), Gaps = 3/111 (2%) Query: 14 RTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHV 73 RT + ++ T+ DL AK L +D +++ V + +A V Sbjct: 37 RTGISERRIVTQENTS-DLCHQVAKQLLEKSGKQASEIDFILVATVTPDFNM-PSVACQV 94 Query: 74 GLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQ 124 +G E A I+ C ++ + + + L G E+ S+ Sbjct: 95 QGAIG-ATEAFAFDISAACSGFVYALSMAEKLVLSGRYQTGLVIGGETFSK 144 >4RYB-A nrPDB Length = 320 Score = 35.8 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 28/81 (34%), Gaps = 1/81 (1%) Query: 45 KVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQ 104 + +D +I+ A V ++GI PA + +C ++ Sbjct: 68 GLDSGEIDLIIVATATPD-MQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANA 126 Query: 105 EICVKEAEVVLCGGTESMSQA 125 I A+ L G E+ S+ Sbjct: 127 YIKSGMAKNALVIGAETFSRI 147 >4EFI-A nrPDB Length = 354 Score = 35.8 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 46/121 (38%), Gaps = 12/121 (9%) Query: 2 ALLRGVF-VVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 + +R V ++ R +A DL A + L+ +++D++I + Sbjct: 43 SAVRDVVKMIGVNR-----RRWADAQTSAGDLCRKAGEKLLAGLGWQADSIDALIF---V 94 Query: 61 QSSSDAIYLARHVGLRVGI--PKETPALTINRLCGSGFQSIVNGCQEICVKEAE-VVLCG 117 + + A L+ + P AL IN C Q++ G I A+ V+L Sbjct: 95 SQTPNYRLPATAFVLQAELDLPASCLALDINLGCSGYPQALWLGMNLIQTGAAKRVLLAV 154 Query: 118 G 118 G Sbjct: 155 G 155 >3HO9-A nrPDB Length = 427 Score = 35.4 bits (80), Expect = 0.044, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 22/40 (55%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMS 123 P+++I SG +I + + I +A+V++ GG E S Sbjct: 170 PSISIATAATSGVHNIGHAARIIAYGDADVMVAGGAEKAS 209 Score = 35.0 bits (79), Expect = 0.067, Method: Composition-based stats. Identities = 28/117 (23%), Positives = 48/117 (41%), Gaps = 10/117 (8%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSG-----CDPSIMGIGPVPAISGALKKA 307 + DGAG +++ + KK A +VG+ +S P G G A++ AL+ A Sbjct: 246 LGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPENGAGAALAMANALRDA 305 Query: 308 GLSLKDMDLVEVNEAFA-----PQYLAVERSLDLDISKTNVNGGAIALGHPLGGSGS 359 G+ + V + + AV+ S+ V+ GH LG +G+ Sbjct: 306 GIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSSTKSMTGHLLGAAGA 362 >1UB7-A nrPDB Length = 322 Score = 35.4 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 24/120 (20%), Positives = 47/120 (39%), Gaps = 5/120 (4%) Query: 6 GVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSD 65 ++V RT +D +DL+ A + L + E VD+VI V ++ D Sbjct: 29 DEWIV--TRTGIKERRVAAEDEYTSDLAFKAVEDLLRRHPGALEGVDAVI---VATNTPD 83 Query: 66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQA 125 A++ ++ + A + C ++ + A+ VL G E++S+ Sbjct: 84 ALFPDTAALVQARFGLKAFAYDLLAGCPGWIYALAQAHALVEAGLAQKVLAVGAEALSKI 143 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%) Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVN 344 A A++KAGL+ +D+ L ++A A L L + VN Sbjct: 225 ATLEAIEKAGLTPEDIRLFVPHQANLRIIDAARERLGLPWERVAVN 270 >3H76-A nrPDB Length = 359 Score = 34.6 bits (78), Expect = 0.068, Method: Composition-based stats. Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 4/111 (3%) Query: 32 LSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRL 91 L AA+ A+ A + PE +D +++ N L A + +G+ + P L I Sbjct: 77 LMVPAARQAIEAAGLLPEDIDLLLV-NTLSPDHHDPSQACLIQPLLGL-RHIPVLDIRAQ 134 Query: 92 CGSGFQSIVNGCQEICVKEAE-VVLCGGTESMSQAPYCVRNVRFGTKLGSD 141 C + +I A V++ G E +S+ C R + L D Sbjct: 135 CSGLLYGLQMARGQILAGLARHVLVVCG-EVLSKRMDCSDRGRNLSILLGD 184 Score = 32.7 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 296 PVPAISGALKKAGLSLKDMDLVEVN 320 VPA A++ AGL +D+DL+ VN Sbjct: 78 MVPAARQAIEAAGLLPEDIDLLLVN 102 >1TQY-A nrPDB Length = 424 Score = 34.6 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 12/129 (9%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIM------GIGPVPAISGALKK 306 +A+GA ++ D+ A I GY C+ M G I AL + Sbjct: 237 LAEGAAMFVLEDYDSALARGARIHAEISGYATR-CNAYHMTGLKADGREMAETIRVALDE 295 Query: 307 AGLSLKDMDLVEVNEAFAPQ-----YLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRI 361 + D+D + + + Q A +R+L +T V+ +GH LG GS Sbjct: 296 SRTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLE 355 Query: 362 TAHLVHELR 370 A V L Sbjct: 356 IAACVLALE 364 Score = 32.7 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCG 117 P ++ C SG S+ N + I A+V+ G Sbjct: 161 PVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAG 194 >4Z87-A nrPDB Length = 525 Score = 33.4 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 54/325 (16%), Positives = 99/325 (30%), Gaps = 63/325 (19%) Query: 133 RFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKA 192 R K+ + S ++T+ + + MA+ + H + EE + + ++ Sbjct: 63 RLTKKITLNAPFVSSPMDTVTEADMAIHMALLGGIGIIHHNCTAEEQAEMVRRVKKYENG 122 Query: 193 ANDA----GYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPV-FKKDGTV-- 245 +A G +K + G V + +P L+ + + F +D T+ Sbjct: 123 FINAPVVVGPDATVADVRRMKNEFGFAGFPVTDDGKPTGKLQGIITSRDIQFVEDETLLV 182 Query: 246 --------------------------TAGNASGVADGAGAVIIA-SEDAVKKHNFTPLAR 278 T + D AG ++ S + K+ PLA Sbjct: 183 SEIMTKDVITGKQGINLEEANQILKNTKKGKLPIVDEAGCLVSMLSRTDLMKNQSYPLAS 242 Query: 279 IVGYFVSGCDPSIMGIGPVPAISGALKK---AGLSLKDMDLVEVNEAFAPQYLAVERSLD 335 + IG + A L AGL + +D + N F + + Sbjct: 243 --KSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKETF 300 Query: 336 LDIS----KTNVNGGAIALGHPLGGSGSRI-------------------TAHLVHELRRR 372 D+ A +L H G G RI V+ + + Sbjct: 301 PDLQVIAGNVVTREQAASLIHA-GADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQF 359 Query: 373 GGKYAVGSACIGGGQGIAVIIQSTA 397 ++ V GG Q I I ++ A Sbjct: 360 ANQFGVPCIADGGVQNIGHITKAIA 384 >1E5M-A nrPDB Length = 416 Score = 33.4 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 54/146 (36%), Gaps = 42/146 (28%) Query: 18 GAYGGLLKDFTATDL---------------SEFAAKAALSAGKVSPETVDSVIMGNVLQS 62 +GG +KDF AT + A++ A++ K+ +++ +G ++ + Sbjct: 51 CRFGGEVKDFDATQFLDRKEAKRMDRFCHFAVCASQQAINDAKLVINELNADEIGVLIGT 110 Query: 63 SSDAIYL---ARHVGLRVG----IPKETPALTINRL--------------------CGSG 95 + + + + L G P P + N C +G Sbjct: 111 GIGGLKVLEDQQTILLDKGPSRCSPFMIPMMIANMASGLTAINLGAKGPNNCTVTACAAG 170 Query: 96 FQSIVNGCQEICVKEAEVVLCGGTES 121 +I + + + A+ ++CGGTE+ Sbjct: 171 SNAIGDAFRLVQNGYAKAMICGGTEA 196 Score = 31.9 bits (71), Expect = 0.51, Method: Composition-based stats. Identities = 29/118 (24%), Positives = 51/118 (43%), Gaps = 14/118 (11%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP-------AISGALK 305 + +G+G +I+ ++ +VGY ++ CD + PVP AI+ ALK Sbjct: 235 MGEGSGILILEELESALARGAKIYGEMVGYAMT-CD-AYHITAPVPDGRGATRAIAWALK 292 Query: 306 KAGLSLKDMDLVEVNEAFAPQ-----YLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 +GL + + + + P A++++L V+ GH LGGSG Sbjct: 293 DSGLKPEMVSYINAHGTSTPANDVTETRAIKQALGNHAYNIAVSSTKSMTGHLLGGSG 350 >6ET0-A nrPDB Length = 365 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 32/97 (32%), Gaps = 10/97 (10%) Query: 274 TPLARIVGYFVSGCDPSIMGIGPVP-AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVER 332 P + + VP A+ AL+KAGL D+D ++ A Sbjct: 239 KPRLYFSLFSDGQNKMASFVPTNVPIAMRRALEKAGLGSDDIDYFVFHQPAPFLVKAWAE 298 Query: 333 SLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHEL 369 + + + +G +G I+ + + L Sbjct: 299 GIGARPEQYQLT---------MGDTGVMISVSIPYTL 326 >4XOX-A nrPDB Length = 404 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 29/170 (17%), Positives = 55/170 (32%), Gaps = 29/170 (17%) Query: 36 AAKAALSAGKVSPETVDSVIMGNVLQSSS-------DAIYLARHVGLRVGIPKETPAL-- 86 + + A++ ++PE V + G V S A+ R G++ P P Sbjct: 78 SLEQAIADAGLTPEQVSNDRTGIVAGSGGASSENQVIAVDTQREKGVKRVGPYMVPRTMS 137 Query: 87 ------------------TINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESM--SQAP 126 +I+ C + I N + I + + ++V GG E + SQ Sbjct: 138 STVSACLATPFKIRGVNYSISSACATSAHCIGNAVELIQLGKQDIVFAGGGEELYWSQTM 197 Query: 127 YCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISR 176 TK + + + D V ++H ++R Sbjct: 198 MFDAMGALSTKYNETPEKASRTYDADRDGFVISGGGGMVVVEELEHALAR 247 >4JD3-A nrPDB Length = 353 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 18/47 (38%), Gaps = 1/47 (2%) Query: 28 TATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVG 74 A DL A AL + P +D + V + ++ AR G Sbjct: 75 KAVDLGVEALLGALDDANLRPSDIDMIATATVTGVAVPSLD-ARIAG 120 >4OQJ-A nrPDB Length = 845 Score = 32.7 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 6/34 (17%), Positives = 15/34 (44%) Query: 84 PALTINRLCGSGFQSIVNGCQEICVKEAEVVLCG 117 P+++ N C + ++ C + + + L G Sbjct: 185 PSVSTNTACSTSLVAVHLACLSLLSGDCTMALAG 218 >2BZ4-A nrPDB Length = 418 Score = 32.7 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 19/49 (38%) Query: 72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 L +I+ C + I N ++I + + ++V GG E Sbjct: 155 SACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGE 203 >4YLT-A nrPDB Length = 316 Score = 32.3 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 61/185 (32%), Gaps = 9/185 (4%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 M ++V RT D T + AA+ AL + + + +I+ Sbjct: 25 MVDTSDEWIV--TRTGIRERRIAGLDETVATMGFQAAEKALEMAGIDKDDIGLIIVAT-T 81 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 SS A V +GI K+ + + C ++ Q + + + G++ Sbjct: 82 SSSHAFPSSACQVQRMLGI-KDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSD 140 Query: 121 SMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPM---AMTAENLAVKHKISRE 177 +S+A R L D L S + + E LA+ + ++ Sbjct: 141 VLSRA--LDPEDRGTIILFGDGAGAVVLGASEQPGIMSTHLHADGRYGELLALPYPDRQQ 198 Query: 178 ECDKY 182 + Y Sbjct: 199 DQPAY 203 Score = 31.9 bits (71), Expect = 0.50, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 29/63 (46%), Gaps = 6/63 (9%) Query: 279 IVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEV-----NEAFAPQYLAVERS 333 I ++G D ++ +G A AL+ AG+ D+ L+ V + AF V+R Sbjct: 39 IRERRIAGLDETVATMG-FQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRM 97 Query: 334 LDL 336 L + Sbjct: 98 LGI 100 >6G2J-R nrPDB Length = 116 Score = 31.9 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 318 EVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHP 353 EVNE FA +A + +++ +GG ALGHP Sbjct: 54 EVNENFAIDLIAQQPVNEVEHRIIACDGGGGALGHP 89 >5XTD-T nrPDB Length = 95 Score = 31.5 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 318 EVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHP 353 EVNE FA +A + +++ +GG ALGHP Sbjct: 34 EVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHP 69 >5GW4-d nrPDB Length = 528 Score = 31.1 bits (69), Expect = 0.81, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 10/85 (11%) Query: 208 VKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVI------ 261 +KT +G+ + D H T L+Q+ L PV + V+A S DG +V+ Sbjct: 48 IKTSRGEIIISNDGH----TILKQMAILHPVARMLVEVSAAQDSEAGDGTTSVVILTGAL 103 Query: 262 IASEDAVKKHNFTPLARIVGYFVSG 286 + + + + P + + Sbjct: 104 LGAAERLLNKGIHPTIIADSFQSAA 128 >4HA6-A nrPDB Length = 508 Score = 31.1 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 17/111 (15%), Positives = 32/111 (28%), Gaps = 9/111 (8%) Query: 33 SEFAAKAALSAGKVSPETV-DSVIMGNVLQSSSDAIYLARHVGLRVG----IPKETPALT 87 + A L + P V D+ +G ++ L H+ L G K P Sbjct: 252 GALESPALLMRSGIGPHDVLDAAGVGCLIDMPDIGRNLQDHL-LGAGNLYAARKPVPPSR 310 Query: 88 INRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKL 138 + S + + + E+V+ G + + L Sbjct: 311 LQH---SESMAYMRADSFTAAGQPEIVVGCGVAPIVSESFPAPAAGSAYSL 358 >5LBT-A nrPDB Length = 237 Score = 31.1 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 29/86 (33%), Gaps = 9/86 (10%) Query: 5 RGVFVVAAKRTPFGAYGGLLKDFTATDL---SEFAAKAALSAGKVSPETVDSVIMGN--- 58 + V +V A + P ++ G LK+ +L + L A + P D I G Sbjct: 4 KKVLIVYAHQEPK-SFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSN 62 Query: 59 --VLQSSSDAIYLARHVGLRVGIPKE 82 V + + L I E Sbjct: 63 PEVFNYGVETHEAYKQRSLASDITDE 88 >1TQY-B nrPDB Length = 415 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 5/78 (6%) Query: 36 AAKAALSAGKVSPETVDSVI---MGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRL- 91 A + AL+ PE VD V G +++A + R G R G+P P T RL Sbjct: 284 AIRLALNDAGTGPEDVDVVFADGAGVPELDAAEARAIGRVFG-REGVPVTVPKTTTGRLY 342 Query: 92 CGSGFQSIVNGCQEICVK 109 G G +V + Sbjct: 343 SGGGPLDVVTALMSLREG 360 >3OYT-A nrPDB Length = 410 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 19/49 (38%) Query: 72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 L + +I+ C + I + + I + + ++V GG E Sbjct: 147 SACLATPFKIKGVNYSISSACATSAHCIGHALELIQLGKQDIVFAGGGE 195 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 43/126 (34%), Gaps = 16/126 (12%) Query: 240 KKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPA 299 +DG V AG G G V++ + A IVGY + D + M Sbjct: 229 DRDGFVIAG-------GGGMVVVEELEHALARGAHIYAEIVGYGATS-DGADMVAPSGEG 280 Query: 300 ISGALKKAGLSLKD-MDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIA-----LGHP 353 ++ A + +D + V+ + + L N AI+ GH Sbjct: 281 AVRCMQMAMAGVDTPIDYMNVHG--TSTPVGDVKELGAIREVFGNNTPAISSTKAMTGHS 338 Query: 354 LGGSGS 359 LG +G Sbjct: 339 LGAAGV 344 >5GUP-F nrPDB Length = 123 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 20/36 (55%) Query: 318 EVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHP 353 EVNE FA +A + ++ + +GG ALGHP Sbjct: 61 EVNENFAIDLIAEQPVSEVGSRVISCDGGGGALGHP 96 >2P1R-A nrPDB Length = 299 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 31/83 (37%), Gaps = 13/83 (15%) Query: 245 VTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGAL 304 + G + + + A+I + PL + S P A+ AL Sbjct: 62 IAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPE--------ALDKAL 113 Query: 305 KK--AGLSLKDMDLVEVNE--AF 323 K AG +++ +D+ VN+ F Sbjct: 114 KLAIAGNAME-IDMAMVNDKTCF 135 >5O31-R nrPDB Length = 96 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 19/36 (52%) Query: 318 EVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHP 353 EVNE FA +A + + + +GG ALGHP Sbjct: 34 EVNENFAIDLIAEQPVSQVGSRVISCDGGGGALGHP 69 >3IL3-A nrPDB Length = 323 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 46/124 (37%), Gaps = 4/124 (3%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 M ++V R+ +D T + AAK A+ A +++P+ ++ +I+ Sbjct: 32 MVDTSDEWIV--TRSGIRERRIAAEDETVATMGFEAAKNAIEAAQINPQDIELIIVATTS 89 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 S A V + I + + C ++ Q I + + L G++ Sbjct: 90 HS-HAYPSAACQVQGLLNIDDAI-SFDLAAACTGFVYALSVADQFIRAGKVKKALVIGSD 147 Query: 121 SMSQ 124 S+ Sbjct: 148 LNSR 151 >3OA3-A nrPDB Length = 288 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 38/114 (33%), Gaps = 16/114 (14%) Query: 19 AYGGLLKDFTATDLSE--FAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLR 76 Y + +D A L+ K L +++ D +I G VL S + A Y+ G Sbjct: 156 RYTDVFQDIRAVRLAAKDAILKVILETSQLTA---DEIIAGCVLSSLAGADYVKTSTGFN 212 Query: 77 VGIPKETPALTINRLCGS-----------GFQSIVNGCQEICVKEAEVVLCGGT 119 ++ +C S G ++I + + + + G Sbjct: 213 GPGASIENVSLMSAVCDSLQSETRVKASGGIRTIEDCVKMVRAGAERLGASAGV 266 >5BNS-A nrPDB Length = 317 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 39/118 (33%), Gaps = 4/118 (3%) Query: 1 MALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVL 60 M ++V RT + T + + AA A+ + + + +++ Sbjct: 25 MVDTSDEWIV--TRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVAT-T 81 Query: 61 QSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGG 118 ++ A + +GI K PA + C ++ Q + + L G Sbjct: 82 SATHAFPSAACQIQSMLGI-KGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVG 138 >3VEW-A nrPDB Length = 576 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 20/41 (48%), Gaps = 4/41 (9%) Query: 293 GIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERS 333 PV A + L +AGL++ D+D V AF A+ R Sbjct: 49 NTAPVQAAAFCLAQAGLTVDDLDAV----AFGWDLPAMYRE 85 >1PV9-A nrPDB Length = 348 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 21/129 (16%), Positives = 42/129 (32%), Gaps = 13/129 (10%) Query: 88 INRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE---SMSQAP------YCVRNVRFGTKL 138 I + C ++++ +EI + E + E M+ A R Sbjct: 133 IEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPH 192 Query: 139 GSD----IKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAAN 194 G I+ D + + L + +T + + E + L++Q+R A Sbjct: 193 GVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAA 252 Query: 195 DAGYFNDEM 203 G E+ Sbjct: 253 KPGMTAKEL 261 >4ANI-C nrPDB Length = 509 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 32/77 (41%), Gaps = 8/77 (10%) Query: 282 YFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMD---LVEVNEAFAPQYLAVERSLDLDI 338 + +GPV AL+ AGL+ D+D LV + A++R L + Sbjct: 274 FEELSAHLVERTMGPV---RQALQDAGLTPADIDKVILVGGSTRIPAVQEAIKRELGKEP 330 Query: 339 SK-TNVNGGAIALGHPL 354 K N + +A+G + Sbjct: 331 HKGVNPD-EVVAIGAAI 346 >6ET3-B nrPDB Length = 283 Score = 28.8 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 12/58 (20%) Query: 297 VPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPL 354 +PA+ AL +A + +++DL+ LA L D N + A +GHPL Sbjct: 39 LPAVREALDEAAVKPEEIDLI--------VGLA----LSPDHLIENRDIMAPKIGHPL 84 >4ZEF-A nrPDB Length = 251 Score = 28.8 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 31/94 (32%), Gaps = 16/94 (17%) Query: 99 IVNGCQEICVKEAEVVLCGGTESMS-----------QAPYCVRNVRFGTKLGSD-IKLED 146 + Q + +A+ ++ G M+ PY ++ K G+D IK D Sbjct: 76 FSSAVQAVESGQADGMVAG----MTITDDRKKAFDFSVPYFDSGIQIAVKKGNDKIKSYD 131 Query: 147 SLWVSLTDQHVQLPMAMTAENLAVKHKISREECD 180 L + A E K+ S + D Sbjct: 132 DLKGKKVGVKIGTESADFLEKNKKKYDYSIKYLD 165 >4XTI-A nrPDB Length = 413 Score = 28.8 bits (63), Expect = 4.8, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 41/130 (31%), Gaps = 27/130 (20%) Query: 294 IGPVPAISGALKK---AGLSLKDMDLVEVNEAFAPQYLAVERSLDLDIS----KTNVNGG 346 IG + A L AGL + +D + N F + + D+ Sbjct: 144 IGTIDADRQRLAMLVEAGLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQ 203 Query: 347 AIALGHPLGGSGSRI-------------------TAHLVHELRRRGGKYAVGSACIGGGQ 387 A +L H G G RI V+ + + ++ V GG Q Sbjct: 204 AASLIHA-GADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQ 262 Query: 388 GIAVIIQSTA 397 I I ++ A Sbjct: 263 NIGHITKAIA 272 >1C5K-A nrPDB Length = 439 Score = 28.4 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 9/44 (20%), Positives = 19/44 (43%), Gaps = 3/44 (6%) Query: 51 VDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALT---INRL 91 +D+V++G V + + +A + G P A +N+ Sbjct: 97 IDAVVVGQVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQ 140 >5VXG-A nrPDB Length = 358 Score = 28.4 bits (62), Expect = 5.6, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 35/93 (37%), Gaps = 6/93 (6%) Query: 299 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 358 A L G +++++D +++ P A +S +D +K G +G + Sbjct: 267 AAKQVL---GWAVEELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGN---IGPAS 320 Query: 359 SRITAHLVHELRRRGGKYAVGSACIGGGQGIAV 391 I + EL R + IG G ++ Sbjct: 321 VPIVLSKLKELGRLKKGDRIALLGIGSGLNCSM 353 >3APY-A nrPDB Length = 310 Score = 28.4 bits (62), Expect = 5.9, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 48/130 (36%), Gaps = 13/130 (10%) Query: 228 TLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARI-VGYFVSG 286 TLE+L+ P F ++T G + + +A ++ PLA + V Sbjct: 34 TLEELKAFRPAFV---SITYGAMGSTRERS----VAWAQRIQSLGLNPLAHLTVAGQSRK 86 Query: 287 CDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVN-EAF--APQYLAVERSLDLDISKTNV 343 ++ + L G + + + E F A + +A+ R D + +V Sbjct: 87 EVAEVLHRFVESGVENLLALRGDPPRGERVFRPHPEGFRYAAELVALIRERYGD--RVSV 144 Query: 344 NGGAIALGHP 353 G A GHP Sbjct: 145 GGAAYPEGHP 154 >6EMK-G nrPDB Length = 426 Score = 28.4 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 22/66 (33%), Gaps = 6/66 (9%) Query: 256 GAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMD 315 G GA + + + TPL + Y C ++ G V K +D Sbjct: 130 GVGADLWV----MDTNGDTPLHVCLEYGSISCMKMLLNEGEVSLDDNVRDKGNWKP--ID 183 Query: 316 LVEVNE 321 + + E Sbjct: 184 VAQTFE 189 >1W27-A nrPDB Length = 716 Score = 28.1 bits (61), Expect = 6.4, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 34/94 (36%), Gaps = 3/94 (3%) Query: 93 GSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSL 152 GSG S+V I AEV+ E M P ++ K ++ + Sbjct: 265 GSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHI 324 Query: 153 TDQHVQLPMAMTAENLAVKHKISREECDKYALQS 186 D A+ L + + + D+YAL++ Sbjct: 325 LD---GSAYVKAAQKLHEMDPLQKPKQDRYALRT 355 >3U0E-A nrPDB Length = 428 Score = 28.1 bits (61), Expect = 6.6, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 33/117 (28%), Gaps = 33/117 (28%) Query: 34 EFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGI----------PKET 83 A A++ ++ E V + G ++ S R + I P Sbjct: 97 HIAMDQAIADAGLTEEEVSNERTGIIMGSG---GPSTRTIVDSADITREKGPKRVGPFAV 153 Query: 84 PA--------------------LTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTE 120 P +I+ C + I N + I + + + GG E Sbjct: 154 PKAMSSTASATLATFFKIKGINYSISSACATSNHCIGNAYEMIQYGKQDRMFAGGCE 210 >2IVO-A nrPDB Length = 330 Score = 28.1 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 4/63 (6%) Query: 262 IASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNE 321 I SED V + F L G P + AL +AG+SL D+D++ Sbjct: 17 IVSEDKVLANVFDTLTTEKGGIHPKEAAEHHARLMKPLLRKALSEAGVSLDDIDVI---- 72 Query: 322 AFA 324 AF+ Sbjct: 73 AFS 75 >2D0P-A nrPDB Length = 610 Score = 28.1 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 32/70 (45%), Gaps = 2/70 (2%) Query: 253 VADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLK 312 + + + V +A+ D T A + G ++ GI A+ + AG+++ Sbjct: 9 IGNSSTEVALATLDEAGALTITHSALAETTGIKGTLRNVFGIQEALALVA--RGAGIAVS 66 Query: 313 DMDLVEVNEA 322 D+ L+ +NEA Sbjct: 67 DISLIRINEA 76 >3ZLH-A nrPDB Length = 455 Score = 27.7 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 21/48 (43%), Gaps = 5/48 (10%) Query: 353 PLGG----SGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQST 396 P+G G R A + H L++ + + +A +G G A + T Sbjct: 189 PVGAPTFKEGLRWGAEVFHALKKILKERGLVTA-VGDEGGFAPKFEGT 235 >5MB9-A nrPDB Length = 590 Score = 27.7 bits (60), Expect = 9.8, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 30/98 (30%), Gaps = 24/98 (24%) Query: 13 KRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARH 72 RT F + L++ A+ + P VD VIM S R Sbjct: 332 ARTVFEGFNRLVES-------------AVKKAGLDPLDVDEVIM------SGGTSNTPRI 372 Query: 73 VG-LRVGIPKET----PALTINRLCGSGFQSIVNGCQE 105 R P+ T P+ + L S Q+ Q Sbjct: 373 AANFRYIFPESTRILAPSTDPSALNPSELQARGAALQA 410 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.139 0.379 Lambda K H 0.267 0.0426 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,311,911 Number of Sequences: 36641 Number of extensions: 625473 Number of successful extensions: 2379 Number of sequences better than 10.0: 130 Number of HSP's better than 10.0 without gapping: 134 Number of HSP's successfully gapped in prelim test: 60 Number of HSP's that attempted gapping in prelim test: 1863 Number of HSP's gapped (non-prelim): 312 length of query: 397 length of database: 10,336,785 effective HSP length: 99 effective length of query: 298 effective length of database: 6,709,326 effective search space: 1999379148 effective search space used: 1999379148 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.7 bits)