BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P42574 (277 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4PRY-A nrPDB 580 e-166 6BGQ-A nrPDB 358 1e-99 5JFT-A nrPDB 314 3e-86 2XZT-A nrPDB 307 3e-84 4FDL-A nrPDB 289 9e-79 3H1P-A nrPDB 282 1e-76 1SHL-A nrPDB 281 2e-76 1RHJ-B nrPDB 221 3e-58 4HVA-A nrPDB 209 7e-55 6DEU-A nrPDB 207 5e-54 3SIR-A nrPDB 199 8e-52 1M72-A nrPDB 191 4e-49 2NN3-C nrPDB 187 4e-48 2AR9-A nrPDB 169 1e-42 4JJ7-A nrPDB 162 1e-40 4ZVU-A nrPDB 156 1e-38 4JB8-A nrPDB 155 1e-38 1I51-A nrPDB 152 1e-37 4M9R-A nrPDB 143 8e-35 4JB8-B nrPDB 137 5e-33 3KJN-A nrPDB 119 1e-27 3QNW-A nrPDB 118 3e-27 3P45-A nrPDB 117 4e-27 3SIP-B nrPDB 109 1e-24 3P4U-B nrPDB 101 3e-22 3SIP-A nrPDB 100 8e-22 3RJM-A nrPDB 91 4e-19 3J9K-B nrPDB 87 8e-18 2FP3-A nrPDB 84 5e-17 3E4C-A nrPDB 77 6e-15 3H13-A nrPDB 69 3e-12 6F6R-A nrPDB 59 2e-09 3KJN-B nrPDB 55 5e-08 3R7N-B nrPDB 49 2e-06 5MMV-B nrPDB 37 0.013 3GSE-A nrPDB 30 0.80 5XTU-A nrPDB 29 2.7 6A96-A nrPDB 28 4.8 6GXV-A nrPDB 27 8.9 >4PRY-A nrPDB Length = 285 Score = 580 bits (1494), Expect = e-166, Method: Compositional matrix adjust. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG Sbjct: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 Query: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS Sbjct: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 Query: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD 180 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD Sbjct: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD 180 Query: 181 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN 240 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN Sbjct: 181 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN 240 Query: 241 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 277 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH Sbjct: 241 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 277 >6BGQ-A nrPDB Length = 175 Score = 358 bits (920), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 174/175 (99%), Positives = 174/175 (99%) Query: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG Sbjct: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 Query: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS Sbjct: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 Query: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETD 175 HGEEGIIFGTNGPVDLKKITNFFRGDRCR LTGKPKLFIIQACRGTELDCGIETD Sbjct: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRDLTGKPKLFIIQACRGTELDCGIETD 175 >5JFT-A nrPDB Length = 249 Score = 314 bits (804), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 149/241 (61%), Positives = 181/241 (75%), Gaps = 2/241 (0%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y ++YP +G CIIINNKNF + TGM R+GTDVDA N+ FR L Y V+ ND T +I Sbjct: 5 YSLNYPNIGHCIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYNDQTVAQI 64 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 ++++ V+ +DHS+ +S VCVLLSHG+EG+ FGT+ VDLK +T+ FRGDRC SL GKPK Sbjct: 65 MQVLTTVAHDDHSRCASLVCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPSLVGKPK 124 Query: 157 LFIIQACRGTELDCGIETDSGVDDDM--ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSW 214 LF IQACRGTELD G+ETD D+ +IPVEADFLYAYST PGYYSWRN+ GSW Sbjct: 125 LFFIQACRGTELDPGVETDHTDHPDIPDGRERIPVEADFLYAYSTVPGYYSWRNTMTGSW 184 Query: 215 FIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELY 274 FIQSLC M+ +Y +LE + I+TRVN KVA +FES S F AKKQIPCIVSMLTKE+Y Sbjct: 185 FIQSLCEMMTKYGSELELLQIMTRVNHKVALDFESTSNMPGFDAKKQIPCIVSMLTKEMY 244 Query: 275 F 275 F Sbjct: 245 F 245 >2XZT-A nrPDB Length = 149 Score = 307 bits (787), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 148/149 (99%), Positives = 148/149 (99%) Query: 27 MDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVR 86 M SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVR Sbjct: 1 MSSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVR 60 Query: 87 NKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGD 146 NKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGD Sbjct: 61 NKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGD 120 Query: 147 RCRSLTGKPKLFIIQACRGTELDCGIETD 175 RCRSLTGKPKLFIIQACRGTELDCGIETD Sbjct: 121 RCRSLTGKPKLFIIQACRGTELDCGIETD 149 >4FDL-A nrPDB Length = 305 Score = 289 bits (739), Expect = 9e-79, Method: Compositional matrix adjust. Identities = 138/242 (57%), Positives = 178/242 (73%), Gaps = 3/242 (1%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + ++ Sbjct: 62 YNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKM 121 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDRC++L KPK Sbjct: 122 QDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPK 181 Query: 157 LFIIQACRGTELDCGIETDSGVDDDMAC---HKIPVEADFLYAYSTAPGYYSWRNSKDGS 213 LF IQACRGTELD GI+ DSG +D +KIPVEADFL+AYST PGYYSWR+ GS Sbjct: 182 LFFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGS 241 Query: 214 WFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKEL 273 WF+Q+LC++L+++ LE M ILTRVN +VA FES S D FH KKQIPC+VSMLTKEL Sbjct: 242 WFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKEL 301 Query: 274 YF 275 YF Sbjct: 302 YF 303 >3H1P-A nrPDB Length = 260 Score = 282 bits (721), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 136/243 (55%), Positives = 176/243 (72%), Gaps = 3/243 (1%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + + Sbjct: 10 QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAK 69 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 + +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDR ++L KP Sbjct: 70 MQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRSKTLLEKP 129 Query: 156 KLFIIQACRGTELDCGIETDSGVDDDMAC---HKIPVEADFLYAYSTAPGYYSWRNSKDG 212 KLF IQACRGTELD GI+ DSG +D +K PVEADFL+AYST PGYYSWR+ G Sbjct: 130 KLFFIQACRGTELDDGIQADSGPINDTDANPRYKAPVEADFLFAYSTVPGYYSWRSPGRG 189 Query: 213 SWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKE 272 SWF+Q+LC++L+++ LE M ILTRVN +VA FES S D FH KKQIPC+VSMLTKE Sbjct: 190 SWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKE 249 Query: 273 LYF 275 LYF Sbjct: 250 LYF 252 >1SHL-A nrPDB Length = 245 Score = 281 bits (719), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 135/240 (56%), Positives = 174/240 (72%), Gaps = 7/240 (2%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + + Sbjct: 3 QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAK 62 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 + +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDRC++L KP Sbjct: 63 MQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKP 122 Query: 156 KLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWF 215 KLF IQACRGTEL GI+ DS +KIPVEADFL+AYST PGYYSWR+ GSWF Sbjct: 123 KLFFIQACRGTELADGIQADSR-------YKIPVEADFLFAYSTVPGYYSWRSPGRGSWF 175 Query: 216 IQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 +Q+LC++L+++ LE M ILTRVN +VA FES S D FH KKQIPC+VSMLTKELYF Sbjct: 176 VQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 235 >1RHJ-B nrPDB Length = 110 Score = 221 bits (562), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 102/102 (100%), Positives = 102/102 (100%) Query: 176 SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI 235 SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI Sbjct: 1 SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI 60 Query: 236 LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 277 LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH Sbjct: 61 LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 102 >4HVA-A nrPDB Length = 265 Score = 209 bits (533), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 105/240 (43%), Positives = 145/240 (60%), Gaps = 1/240 (0%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL EE+ Sbjct: 14 YKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEEL 73 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL GKPK Sbjct: 74 LLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPK 133 Query: 157 LFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFI 216 +FIIQACRG + D + V D + + +P ADFL YS A GYYS R + +GSW+I Sbjct: 134 IFIIQACRGNQHDVPV-IPLDVVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYI 192 Query: 217 QSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 276 Q LC ML +Y LEF +LT VNRKV+ F D + KKQ+PC SMLTK+L+F+ Sbjct: 193 QDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFF 252 >6DEU-A nrPDB Length = 302 Score = 207 bits (526), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 106/253 (41%), Positives = 146/253 (57%), Gaps = 13/253 (5%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL EE+ Sbjct: 38 YKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEEL 97 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL GKPK Sbjct: 98 LLKIHEVSTVSHTDADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPK 157 Query: 157 LFIIQACRGTELDCGIETDSGVD-------------DDMACHKIPVEADFLYAYSTAPGY 203 +FIIQACRG + D + VD D + + +P ADFL YS A GY Sbjct: 158 IFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSVAEGY 217 Query: 204 YSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIP 263 YS R + +GSW+IQ LC ML +Y LEF +LT VNRKV+ F D + KKQ+P Sbjct: 218 YSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVP 277 Query: 264 CIVSMLTKELYFY 276 C SMLTK+L+F+ Sbjct: 278 CFASMLTKKLHFF 290 >3SIR-A nrPDB Length = 259 Score = 199 bits (507), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 104/245 (42%), Positives = 149/245 (60%), Gaps = 8/245 (3%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M + G+ +I N+++F T + SR+GT+VD NL + L +EV D ++I Sbjct: 13 YNMRHKNRGMALIFNHEHFEVPT-LKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDI 71 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + + ++HS + +LSHGE G I+ + L I +FF + C SL GKPK Sbjct: 72 LRTIEYSASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPK 131 Query: 157 LFIIQACRGTELDCGI-----ETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKD 211 LF IQAC+G LD G+ +T++ D M+ +KIPV ADFL AYST PG+YSWRN+ Sbjct: 132 LFFIQACQGDRLDGGVTMQRSQTETDGDSSMS-YKIPVHADFLIAYSTVPGFYSWRNTTR 190 Query: 212 GSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDAT-FHAKKQIPCIVSMLT 270 GSWF+QSLCA L +L+ + +LT V ++VA +FES + D H +KQIPCI +MLT Sbjct: 191 GSWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLT 250 Query: 271 KELYF 275 + L F Sbjct: 251 RILRF 255 >1M72-A nrPDB Length = 272 Score = 191 bits (484), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 99/245 (40%), Positives = 150/245 (61%), Gaps = 10/245 (4%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M++ G+ II N+++F + + SR+GT+VD+ NL + + L ++V +L EEI Sbjct: 25 YNMNHKHRGMAIIFNHEHFDIHS-LKSRTGTNVDSDNLSKVLKTLGFKVTVFPNLKSEEI 83 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + ++ ++ DHS + +L+HGE G+++ + + +F D+C +L GKPK Sbjct: 84 NKFIQQTAEMDHSDADCLLVAVLTHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 143 Query: 157 LFIIQACRGTELDCGI-----ETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKD 211 LF IQAC+G LD GI ETD ++IPV ADFL A+ST PGY+SWRN+ Sbjct: 144 LFFIQACQGDRLDGGITLSRTETDGSPS---TSYRIPVHADFLIAFSTVPGYFSWRNTTR 200 Query: 212 GSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFD-ATFHAKKQIPCIVSMLT 270 GSWF+Q+LC L+ + + + +LT V +KVA +FES + D A H +KQ+PCI SMLT Sbjct: 201 GSWFMQALCEELRYAGTERDILTLLTFVCQKVALDFESNAPDSAMMHQQKQVPCITSMLT 260 Query: 271 KELYF 275 + L F Sbjct: 261 RLLVF 265 >2NN3-C nrPDB Length = 310 Score = 187 bits (475), Expect = 4e-48, Method: Compositional matrix adjust. Identities = 98/245 (40%), Positives = 149/245 (60%), Gaps = 10/245 (4%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M++ G+ II N+++F + + SR+GT+VD+ NL + + L ++V +L EEI Sbjct: 53 YNMNHKHRGMAIIFNHEHFDIHS-LKSRTGTNVDSDNLSKVLKTLGFKVTVFPNLKSEEI 111 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + ++ ++ DHS + +L+ GE G+++ + + +F D+C +L GKPK Sbjct: 112 NKFIQQTAEMDHSDADCLLVAVLTAGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 171 Query: 157 LFIIQACRGTELDCGI-----ETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKD 211 LF IQAC+G LD GI ETD ++IPV ADFL A+ST PGY+SWRN+ Sbjct: 172 LFFIQACQGDRLDGGITLSRTETDGSPS---TSYRIPVHADFLIAFSTVPGYFSWRNTTR 228 Query: 212 GSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFD-ATFHAKKQIPCIVSMLT 270 GSWF+Q+LC L+ + + + +LT V +KVA +FES + D A H +KQ+PCI SMLT Sbjct: 229 GSWFMQALCEELRYAGTERDILTLLTFVCQKVALDFESNAPDSAMMHQQKQVPCITSMLT 288 Query: 271 KELYF 275 + L F Sbjct: 289 RLLVF 293 >2AR9-A nrPDB Length = 278 Score = 169 bits (429), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/274 (34%), Positives = 145/274 (52%), Gaps = 42/274 (15%) Query: 34 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTR 93 D +Y + G C+IINN NF + +G+ +R+G+++D LR F +L + V K DLT Sbjct: 12 DLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTA 71 Query: 94 EEIVELMRDVSKEDHSKRSSFVCVLLSHGEE-------GIIFGTNG-PVDLKKITNFFRG 145 +++V + +++++DH V V+LSHG + G ++GT+G PV ++KI N F G Sbjct: 72 KKMVLALLELARQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNG 131 Query: 146 DRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDM----------------------- 182 C SL GKPKLF IQA G + D G E S +D Sbjct: 132 TSCPSLGGKPKLFFIQASGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQL 191 Query: 183 -ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNR 241 A +P +D +YST PG+ SWR+ K GSW++++L + +Q+A + +L RV Sbjct: 192 DAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVAN 251 Query: 242 KVATEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 V+ + KQ+PCIVSML K+L+F Sbjct: 252 AVSVK----------GIYKQMPCIVSMLRKKLFF 275 >4JJ7-A nrPDB Length = 275 Score = 162 bits (410), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 100/267 (37%), Positives = 149/267 (55%), Gaps = 24/267 (8%) Query: 27 MDSGISLDNSYKMDYPEMGLCIIINNKNFHKST-------GMTSRSGTDVDAANLRETFR 79 M +LD Y+M G C+IINN NF K+ + R+GT +DA L TF Sbjct: 1 MSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFE 60 Query: 80 NLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGP-VDLKK 138 L +E++ +D T E+I E+++ DHS F+C +LSHG++GII+GT+G + + Sbjct: 61 ELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYE 120 Query: 139 ITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGI--ETDSG----VDDDMACHK---IPV 189 +T+ F G +C SL GKPK+F IQAC+G GI ETDS ++ D++ + IP Sbjct: 121 LTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPD 180 Query: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL-EFMHILTRVNRKVATEFE 248 EADFL +T S+RN +G+W+IQSLC L++ + + + ILT VN +V+ + Sbjct: 181 EADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNK-- 238 Query: 249 SFSFDATFHAKKQIPCIVSMLTKELYF 275 D + KQ+P L K+L F Sbjct: 239 ----DDKKNMGKQMPQPTFTLRKKLVF 261 >4ZVU-A nrPDB Length = 198 Score = 156 bits (394), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 73/140 (52%), Positives = 100/140 (71%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + + Sbjct: 59 QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAK 118 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 + +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDRC++L KP Sbjct: 119 MQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKP 178 Query: 156 KLFIIQACRGTELDCGIETD 175 KLF IQACRGTELD GI+ D Sbjct: 179 KLFFIQACRGTELDDGIQAD 198 >4JB8-A nrPDB Length = 175 Score = 155 bits (393), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 73/140 (52%), Positives = 100/140 (71%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + + Sbjct: 36 QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAK 95 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 + +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDRC++L KP Sbjct: 96 MQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKP 155 Query: 156 KLFIIQACRGTELDCGIETD 175 KLF IQACRGTELD GI+ D Sbjct: 156 KLFFIQACRGTELDDGIQAD 175 >1I51-A nrPDB Length = 148 Score = 152 bits (385), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 72/140 (51%), Positives = 99/140 (70%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + + Sbjct: 9 QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAK 68 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 + +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRG RC++L KP Sbjct: 69 MQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGARCKTLLEKP 128 Query: 156 KLFIIQACRGTELDCGIETD 175 KLF IQACRGTELD GI+ D Sbjct: 129 KLFFIQACRGTELDDGIQAD 148 >4M9R-A nrPDB Length = 306 Score = 143 bits (361), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 88/260 (33%), Positives = 131/260 (50%), Gaps = 35/260 (13%) Query: 45 GLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVS 104 G+C+IINN++F + M +R+GT D NL FR + Y V K++LT ++ +RD + Sbjct: 46 GMCLIINNEHFEQ---MPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGMLLTIRDFA 102 Query: 105 KEDHSKRSSFVCVLLSHGEEGIIFGTNG-PVDLKKITNFFRGDRCRSLTGKPKLFIIQAC 163 K + S S + V+LSHGEE +I G + P+ +I + L KPK+ +QA Sbjct: 103 KHE-SHGDSAILVILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKPKIVFVQAS 161 Query: 164 RGTELDCGIETDSGVD------------------DDMAC---------HKIPVEADFLYA 196 RG D G VD + + C K P +AD L A Sbjct: 162 RGERRDNGFPVLDSVDGVPAFLRRGWDNRDGPLFNFLGCVRPQVQQVWRKKPSQADILIA 221 Query: 197 YSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATF 256 Y+T Y SWRNS GSWFIQ++C + +A ++ + +LT VN+KVA F++ Sbjct: 222 YATTAQYVSWRNSARGSWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQTSQGSNIL 281 Query: 257 HAKKQIPCIVSMLTKELYFY 276 KQ+P + S L K+ YF+ Sbjct: 282 ---KQMPEMTSRLLKKFYFW 298 >4JB8-B nrPDB Length = 105 Score = 137 bits (345), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 62/91 (68%), Positives = 74/91 (81%) Query: 185 HKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVA 244 +KIPVEADFL+AYST PGYYSWR+ GSWF+Q+LC++L+++ LE M ILTRVN +VA Sbjct: 5 YKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVA 64 Query: 245 TEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 FES S D FH KKQIPC+VSMLTKELYF Sbjct: 65 RHFESQSDDPHFHEKKQIPCVVSMLTKELYF 95 >3KJN-A nrPDB Length = 164 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 64/154 (41%), Positives = 92/154 (59%), Gaps = 10/154 (6%) Query: 32 SLDNSYKMDYPEMGLCIIINNKNFHKST-------GMTSRSGTDVDAANLRETFRNLKYE 84 +LD Y+M G C+IINN NF K+ + R+GT +DA L TF L +E Sbjct: 11 TLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFE 70 Query: 85 VRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGP-VDLKKITNFF 143 ++ +D T E+I E+++ DHS F+C +LSHG++GII+GT+G + ++T+ F Sbjct: 71 IKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQF 130 Query: 144 RGDRCRSLTGKPKLFIIQACRGTELDCGI--ETD 175 G +C SL GKPK+F IQAC+G GI ETD Sbjct: 131 TGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETD 164 >3QNW-A nrPDB Length = 156 Score = 118 bits (296), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 56/136 (41%), Positives = 82/136 (60%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL EE+ Sbjct: 14 YKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEEL 73 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL GKPK Sbjct: 74 LLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPK 133 Query: 157 LFIIQACRGTELDCGI 172 +FIIQACRG + D + Sbjct: 134 IFIIQACRGNQHDVPV 149 >3P45-A nrPDB Length = 179 Score = 117 bits (294), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 56/136 (41%), Positives = 82/136 (60%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL EE+ Sbjct: 37 YKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLKAEEL 96 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL GKPK Sbjct: 97 LLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLVGKPK 156 Query: 157 LFIIQACRGTELDCGI 172 +FIIQACRG + D + Sbjct: 157 IFIIQACRGNQHDVPV 172 >3SIP-B nrPDB Length = 109 Score = 109 bits (272), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 52/97 (53%), Positives = 67/97 (69%), Gaps = 1/97 (1%) Query: 180 DDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRV 239 D +KIPV ADFL AYST PG+YSWRN+ GSWF+QSLCA L +L+ + +LT V Sbjct: 2 DSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFV 61 Query: 240 NRKVATEFESFSFDAT-FHAKKQIPCIVSMLTKELYF 275 ++VA +FES + D H +KQIPCI +MLT+ L F Sbjct: 62 CQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRILRF 98 >3P4U-B nrPDB Length = 108 Score = 101 bits (252), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 48/97 (49%), Positives = 62/97 (63%) Query: 180 DDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRV 239 D + + +P ADFL YS A GYYS R + +GSW+IQ LC ML +Y LEF +LT V Sbjct: 1 DAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLV 60 Query: 240 NRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 276 NRKV+ F D + KKQ+PC SMLTK+L+F+ Sbjct: 61 NRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFF 97 >3SIP-A nrPDB Length = 157 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 50/136 (36%), Positives = 76/136 (55%), Gaps = 1/136 (0%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M + G+ +I N+++F T + SR+GT+VD NL + L +EV D ++I Sbjct: 13 YNMRHKNRGMALIFNHEHFEVPT-LKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDI 71 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + + ++HS + +LSHGE G I+ + L I +FF + C SL GKPK Sbjct: 72 LRTIEYAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPK 131 Query: 157 LFIIQACRGTELDCGI 172 LF IQAC+G LD G+ Sbjct: 132 LFFIQACQGDRLDGGV 147 >3RJM-A nrPDB Length = 169 Score = 91.3 bits (225), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 50/140 (35%), Positives = 79/140 (56%), Gaps = 2/140 (1%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 +Y++ GL ++++N +F + RSG DVD + L F+ L Y+V D T +E Sbjct: 27 AYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQE 86 Query: 96 IVELMRDVSK-EDHSKRSSFVCVLLSHGEEGIIFGTNGPV-DLKKITNFFRGDRCRSLTG 153 + E +++ ++ H S + LLSHG EG I+G +G + L+++ F C SL Sbjct: 87 MQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQN 146 Query: 154 KPKLFIIQACRGTELDCGIE 173 KPK+F IQACRG E D G++ Sbjct: 147 KPKMFFIQACRGDETDRGVD 166 >3J9K-B nrPDB Length = 450 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 67/265 (25%), Positives = 118/265 (44%), Gaps = 35/265 (13%) Query: 8 VDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYP-EMGLCIIINNKNFHKSTGMTSRSG 66 VD +K + K IHG +S G +YKM G+ +++N ++ R G Sbjct: 165 VDGPEVK--KSKKIHGGDSAILG-----TYKMQSRFNRGVLLMVNIMDYPDQN--RRRIG 215 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSS-FVCVLLSHG--- 122 + D+ +L F+ L + + ++ +++ +L+ V+ + + + FV VL++HG Sbjct: 216 AEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSV 275 Query: 123 --EEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG--- 177 +E + F VD++KI + F+ +C L KPK+ + CRG E D G + G Sbjct: 276 EGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLM 335 Query: 178 -----------VDDDM-----ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCA 221 D +P AD L Y+ PGY + R+ GSW+IQ C Sbjct: 336 EPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQ 395 Query: 222 MLKQYADKLEFMHILTRVNRKVATE 246 ++ +A + IL + + V + Sbjct: 396 VMADHAHDTDLEDILKKTSEAVGNK 420 >2FP3-A nrPDB Length = 316 Score = 84.3 bits (207), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 66/265 (24%), Positives = 117/265 (44%), Gaps = 35/265 (13%) Query: 8 VDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYP-EMGLCIIINNKNFHKSTGMTSRSG 66 VD +K + K IHG +S G +YKM G+ +++N ++ R G Sbjct: 31 VDGPEVK--KSKKIHGGDSAILG-----TYKMQSRFNRGVLLMVNIMDYPDQN--RRRIG 81 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSS-FVCVLLSHG--- 122 + D+ +L F+ L + + ++ +++ +L+ V+ + + + FV VL++HG Sbjct: 82 AEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSV 141 Query: 123 --EEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG--- 177 +E + F VD++KI + F+ +C L KPK+ + RG E D G + G Sbjct: 142 EGKEKVEFRDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFARGDEYDLGHPKNQGNLM 201 Query: 178 -----------VDDDM-----ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCA 221 D +P AD L Y+ PGY + R+ GSW+IQ C Sbjct: 202 EPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQ 261 Query: 222 MLKQYADKLEFMHILTRVNRKVATE 246 ++ +A + IL + + V + Sbjct: 262 VMADHAHDTDLEDILKKTSEAVGNK 286 >3E4C-A nrPDB Length = 302 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 72/252 (28%), Positives = 106/252 (42%), Gaps = 35/252 (13%) Query: 46 LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIV-ELMRDVS 104 L +II N+ F + R+G +VD + +NL Y V K +LT ++ EL Sbjct: 62 LALIICNEEFD---SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAH 118 Query: 105 KEDHSKRSSFVCVLLSHG-EEGIIFGTNGP-----VDLKKITNFFRGDRCRSLTGKPKLF 158 + +H S V +SHG EGI + + L I N C SL KPK+ Sbjct: 119 RPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVI 178 Query: 159 IIQACRG-------------TELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYS 205 IIQA RG + + T +DD A K +E DF+ S+ P S Sbjct: 179 IIQAARGDSPGVVWFKDSVGVSGNLSLPTTEEFEDD-AIKKAHIEKDFIAFCSSTPDNVS 237 Query: 206 WRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCI 265 WR+ GS FI L +++YA + I +V FSF+ + Q+P Sbjct: 238 WRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVR---------FSFEQP-DGRAQMPTT 287 Query: 266 VSM-LTKELYFY 276 + LT+ Y + Sbjct: 288 ERVTLTRCFYLF 299 >3H13-A nrPDB Length = 272 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 63/224 (28%), Positives = 98/224 (43%), Gaps = 33/224 (14%) Query: 19 KIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETF 78 K I SE+ + YKM +G+C+II+ G + + LR+TF Sbjct: 18 KSIQESEAFLPQSIPEERYKMKSKPLGICLIIDC------------IGNETEL--LRDTF 63 Query: 79 RNLKYEVRNKNDLTREEIVELMRDVS-KEDHSKRSSFVCVLLSHGEEGIIFG---TNGPV 134 +L YEV+ L+ I +++ + +H SFVCVL+S G ++G T+ + Sbjct: 64 TSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSGL 123 Query: 135 DLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHK-------- 186 L I F GD C L GKPK+F IQ +E +E S ++ D K Sbjct: 124 PLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ--LENSSLLEVDGPAMKNVEFKAQK 181 Query: 187 -----IPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQ 225 + EADF ++ TA ++ S ++Q L L+Q Sbjct: 182 RGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQ 225 >6F6R-A nrPDB Length = 180 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 43/127 (33%), Positives = 59/127 (46%), Gaps = 10/127 (7%) Query: 46 LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIV-ELMRDVS 104 L +II N+ F + R+G +VD + +NL Y V K +LT ++ EL Sbjct: 47 LALIICNEEFD---SIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAH 103 Query: 105 KEDHSKRSSFVCVLLSHG-EEGIIFGTNGP-----VDLKKITNFFRGDRCRSLTGKPKLF 158 + +H S V +SHG EGI + + L I N C SL KPK+ Sbjct: 104 RPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVI 163 Query: 159 IIQACRG 165 IIQACRG Sbjct: 164 IIQACRG 170 >3KJN-B nrPDB Length = 95 Score = 54.7 bits (130), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 7/90 (7%) Query: 187 IPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL-EFMHILTRVNRKVAT 245 IP EADFL +T S+RN +G+W+IQSLC L++ + + + ILT VN +V+ Sbjct: 9 IPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSN 68 Query: 246 EFESFSFDATFHAKKQIPCIVSMLTKELYF 275 + D + KQ+P L K+L F Sbjct: 69 K------DDKKNMGKQMPQPTFTLRKKLVF 92 >3R7N-B nrPDB Length = 112 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 1/91 (1%) Query: 186 KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVAT 245 ++P +D + Y+ G + RN+K GSW+I++L + + A + +L +VN + Sbjct: 9 RLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVN-ALIK 67 Query: 246 EFESFSFDATFHAKKQIPCIVSMLTKELYFY 276 + E ++ FH K++ S L + LY + Sbjct: 68 DREGYAPGTEFHRCKEMSEYCSTLCRHLYLF 98 >5MMV-B nrPDB Length = 89 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 182 MACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNR 241 MA K +E DF+ S+ P SWR+ GS FI L +++YA + I R Sbjct: 1 MAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIF----R 56 Query: 242 KVATEFES 249 KV FE Sbjct: 57 KVRFSFEQ 64 >3GSE-A nrPDB Length = 458 Score = 30.4 bits (67), Expect = 0.80, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 11/65 (16%) Query: 155 PKLFIIQACRGTELDCGIETDSGVDDD-----------MACHKIPVEADFLYAYSTAPGY 203 P+L I++ + T L + +++ + D MA +PV + S PGY Sbjct: 131 PRLEILRRGKKTSLTLNLSSETSLQKDALQAITFIDQLMAARALPVLNARIQHSSHTPGY 190 Query: 204 YSWRN 208 WRN Sbjct: 191 PQWRN 195 >5XTU-A nrPDB Length = 360 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 4/43 (9%) Query: 58 STGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELM 100 + G T++SG DV L T + +K + NK T E+V M Sbjct: 151 ANGFTAKSGLDV----LTNTGQQIKLRIANKGQFTGNELVSYM 189 >6A96-A nrPDB Length = 392 Score = 28.1 bits (61), Expect = 4.8, Method: Compositional matrix adjust. Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 26/113 (23%) Query: 179 DDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTR 238 D M H P++ YAY + Y W N S + + L QY H++ Sbjct: 179 DFPMDAHACPLKFG-SYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQY-------HLM-- 228 Query: 239 VNRKVATEFESFS------FDATFHAKKQI---------PCIVSMLTKELYFY 276 + V TE S S A FH K++I PCI++++ ++ F+ Sbjct: 229 -GQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFW 280 >6GXV-A nrPDB Length = 484 Score = 26.9 bits (58), Expect = 8.9, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 148 CRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWR 207 +S TGK LF + T L ++ + M+ +P+ +F A + GYY R Sbjct: 251 VKSTTGKSNLFAVGEYWNTSLGALENYENKTNWSMSLFDVPLHMNFQ-AAANGGGYYDMR 309 Query: 208 N 208 N Sbjct: 310 N 310 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4PRY-A nrPDB 416 e-117 4FDL-A nrPDB 347 3e-96 3H1P-A nrPDB 343 4e-95 5JFT-A nrPDB 340 5e-94 1SHL-A nrPDB 336 7e-93 4HVA-A nrPDB 327 5e-90 3SIR-A nrPDB 323 7e-89 6DEU-A nrPDB 321 2e-88 1M72-A nrPDB 312 9e-86 2NN3-C nrPDB 308 2e-84 4JJ7-A nrPDB 301 1e-82 2AR9-A nrPDB 276 8e-75 4M9R-A nrPDB 268 2e-72 6BGQ-A nrPDB 266 1e-71 3J9K-B nrPDB 251 2e-67 2FP3-A nrPDB 245 1e-65 3E4C-A nrPDB 227 3e-60 2XZT-A nrPDB 224 4e-59 3H13-A nrPDB 207 3e-54 4JB8-A nrPDB 203 5e-53 1I51-A nrPDB 202 9e-53 4ZVU-A nrPDB 202 1e-52 3KJN-A nrPDB 202 2e-52 3P45-A nrPDB 201 4e-52 3QNW-A nrPDB 200 5e-52 3SIP-A nrPDB 197 6e-51 3RJM-A nrPDB 178 2e-45 1RHJ-B nrPDB 152 1e-37 4JB8-B nrPDB 149 1e-36 6F6R-A nrPDB 141 3e-34 3SIP-B nrPDB 140 8e-34 3P4U-B nrPDB 133 7e-32 3R7N-B nrPDB 115 2e-26 3KJN-B nrPDB 106 9e-24 Sequences not found previously or not previously below threshold: 5MMV-B nrPDB 94 5e-20 3V4O-A nrPDB 39 0.002 3V4L-A nrPDB 35 0.028 1WNH-A nrPDB 28 3.1 5FM1-B nrPDB 28 3.4 6FAK-A nrPDB 27 7.1 2F31-A nrPDB 27 7.6 2BAP-B nrPDB 27 8.5 1Z2C-B nrPDB 27 9.1 >4PRY-A nrPDB Length = 285 Score = 416 bits (1069), Expect = e-117, Method: Composition-based stats. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG Sbjct: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 Query: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS Sbjct: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 Query: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD 180 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD Sbjct: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD 180 Query: 181 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN 240 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN Sbjct: 181 DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN 240 Query: 241 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 277 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH Sbjct: 241 RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 277 >4FDL-A nrPDB Length = 305 Score = 347 bits (891), Expect = 3e-96, Method: Composition-based stats. Identities = 144/272 (52%), Positives = 188/272 (69%), Gaps = 7/272 (2%) Query: 7 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG 66 S+ SK KN+ + I + Y M++ ++G CIIINNKNF K TGM R+G Sbjct: 36 SLFSKKKKNVTMRSIKTTRD----RVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG 91 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI 126 TD DA L + FR+L ++V ND + ++ +L++ S+EDH+ + F C+LLSHGEE + Sbjct: 92 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV 151 Query: 127 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDM---A 183 I+G +G +K +T FRGDRC++L KPKLF IQACRGTELD GI+ DSG +D Sbjct: 152 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADSGPINDTDANP 211 Query: 184 CHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKV 243 +KIPVEADFL+AYST PGYYSWR+ GSWF+Q+LC++L+++ LE M ILTRVN +V Sbjct: 212 RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRV 271 Query: 244 ATEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 A FES S D FH KKQIPC+VSMLTKELYF Sbjct: 272 ARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 303 >3H1P-A nrPDB Length = 260 Score = 343 bits (880), Expect = 4e-95, Method: Composition-based stats. Identities = 136/247 (55%), Positives = 176/247 (71%), Gaps = 3/247 (1%) Query: 32 SLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDL 91 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND Sbjct: 6 VPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDC 65 Query: 92 TREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSL 151 + ++ +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDR ++L Sbjct: 66 SCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRSKTL 125 Query: 152 TGKPKLFIIQACRGTELDCGIETDSGVDDDM---ACHKIPVEADFLYAYSTAPGYYSWRN 208 KPKLF IQACRGTELD GI+ DSG +D +K PVEADFL+AYST PGYYSWR+ Sbjct: 126 LEKPKLFFIQACRGTELDDGIQADSGPINDTDANPRYKAPVEADFLFAYSTVPGYYSWRS 185 Query: 209 SKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSM 268 GSWF+Q+LC++L+++ LE M ILTRVN +VA FES S D FH KKQIPC+VSM Sbjct: 186 PGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSM 245 Query: 269 LTKELYF 275 LTKELYF Sbjct: 246 LTKELYF 252 >5JFT-A nrPDB Length = 249 Score = 340 bits (871), Expect = 5e-94, Method: Composition-based stats. Identities = 149/242 (61%), Positives = 181/242 (74%), Gaps = 2/242 (0%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y ++YP +G CIIINNKNF + TGM R+GTDVDA N+ FR L Y V+ ND T + Sbjct: 4 RYSLNYPNIGHCIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYIVKVYNDQTVAQ 63 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 I++++ V+ +DHS+ +S VCVLLSHG+EG+ FGT+ VDLK +T+ FRGDRC SL GKP Sbjct: 64 IMQVLTTVAHDDHSRCASLVCVLLSHGDEGVFFGTDTSVDLKSLTSLFRGDRCPSLVGKP 123 Query: 156 KLFIIQACRGTELDCGIETDSGVDDDMA--CHKIPVEADFLYAYSTAPGYYSWRNSKDGS 213 KLF IQACRGTELD G+ETD D+ +IPVEADFLYAYST PGYYSWRN+ GS Sbjct: 124 KLFFIQACRGTELDPGVETDHTDHPDIPDGRERIPVEADFLYAYSTVPGYYSWRNTMTGS 183 Query: 214 WFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKEL 273 WFIQSLC M+ +Y +LE + I+TRVN KVA +FES S F AKKQIPCIVSMLTKE+ Sbjct: 184 WFIQSLCEMMTKYGSELELLQIMTRVNHKVALDFESTSNMPGFDAKKQIPCIVSMLTKEM 243 Query: 274 YF 275 YF Sbjct: 244 YF 245 >1SHL-A nrPDB Length = 245 Score = 336 bits (861), Expect = 7e-93, Method: Composition-based stats. Identities = 135/240 (56%), Positives = 174/240 (72%), Gaps = 7/240 (2%) Query: 36 SYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREE 95 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND + + Sbjct: 3 QYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAK 62 Query: 96 IVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKP 155 + +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRGDRC++L KP Sbjct: 63 MQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKP 122 Query: 156 KLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWF 215 KLF IQACRGTEL GI+ DS +KIPVEADFL+AYST PGYYSWR+ GSWF Sbjct: 123 KLFFIQACRGTELADGIQADS-------RYKIPVEADFLFAYSTVPGYYSWRSPGRGSWF 175 Query: 216 IQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 +Q+LC++L+++ LE M ILTRVN +VA FES S D FH KKQIPC+VSMLTKELYF Sbjct: 176 VQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 235 >4HVA-A nrPDB Length = 265 Score = 327 bits (837), Expect = 5e-90, Method: Composition-based stats. Identities = 105/244 (43%), Positives = 145/244 (59%), Gaps = 1/244 (0%) Query: 33 LDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLT 92 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL Sbjct: 10 PAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLK 69 Query: 93 REEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLT 152 EE++ + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL Sbjct: 70 AEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLV 129 Query: 153 GKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDG 212 GKPK+FIIQACRG + D + V D + + +P ADFL YS A GYYS R + +G Sbjct: 130 GKPKIFIIQACRGNQHDVPV-IPLDVVDAASVYTLPAGADFLMCYSVAEGYYSHRETVNG 188 Query: 213 SWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKE 272 SW+IQ LC ML +Y LEF +LT VNRKV+ F D + KKQ+PC SMLTK+ Sbjct: 189 SWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKK 248 Query: 273 LYFY 276 L+F+ Sbjct: 249 LHFF 252 >3SIR-A nrPDB Length = 259 Score = 323 bits (827), Expect = 7e-89, Method: Composition-based stats. Identities = 102/244 (41%), Positives = 143/244 (58%), Gaps = 6/244 (2%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M + G+ +I N+++F T + SR+GT+VD NL + L +EV D ++I Sbjct: 13 YNMRHKNRGMALIFNHEHFEVPT-LKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDI 71 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + + ++HS + +LSHGE G I+ + L I +FF + C SL GKPK Sbjct: 72 LRTIEYSASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPK 131 Query: 157 LFIIQACRGTELDCGI----ETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDG 212 LF IQAC+G LD G+ D +KIPV ADFL AYST PG+YSWRN+ G Sbjct: 132 LFFIQACQGDRLDGGVTMQRSQTETDGDSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRG 191 Query: 213 SWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDAT-FHAKKQIPCIVSMLTK 271 SWF+QSLCA L +L+ + +LT V ++VA +FES + D H +KQIPCI +MLT+ Sbjct: 192 SWFMQSLCAELAANGKRLDILTLLTFVCQRVAVDFESCTPDTPEMHQQKQIPCITTMLTR 251 Query: 272 ELYF 275 L F Sbjct: 252 ILRF 255 >6DEU-A nrPDB Length = 302 Score = 321 bits (823), Expect = 2e-88, Method: Composition-based stats. Identities = 105/257 (40%), Positives = 147/257 (57%), Gaps = 13/257 (5%) Query: 33 LDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLT 92 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL Sbjct: 34 PAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLK 93 Query: 93 REEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLT 152 EE++ + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL Sbjct: 94 AEELLLKIHEVSTVSHTDADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLV 153 Query: 153 GKPKLFIIQACRGTELDCGI-------------ETDSGVDDDMACHKIPVEADFLYAYST 199 GKPK+FIIQACRG + D + +T+ D + + +P ADFL YS Sbjct: 154 GKPKIFIIQACRGNQHDVPVIPLDVVDNQTEKLDTNITEVDAASVYTLPAGADFLMCYSV 213 Query: 200 APGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAK 259 A GYYS R + +GSW+IQ LC ML +Y LEF +LT VNRKV+ F D + K Sbjct: 214 AEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLVNRKVSQRRVDFCKDPSAIGK 273 Query: 260 KQIPCIVSMLTKELYFY 276 KQ+PC SMLTK+L+F+ Sbjct: 274 KQVPCFASMLTKKLHFF 290 >1M72-A nrPDB Length = 272 Score = 312 bits (800), Expect = 9e-86, Method: Composition-based stats. Identities = 99/243 (40%), Positives = 151/243 (62%), Gaps = 6/243 (2%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M++ G+ II N+++F + SR+GT+VD+ NL + + L ++V +L EEI Sbjct: 25 YNMNHKHRGMAIIFNHEHFDIH-SLKSRTGTNVDSDNLSKVLKTLGFKVTVFPNLKSEEI 83 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + ++ ++ DHS + +L+HGE G+++ + + +F D+C +L GKPK Sbjct: 84 NKFIQQTAEMDHSDADCLLVAVLTHGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 143 Query: 157 LFIIQACRGTELDCGIETDSGVDDDMA---CHKIPVEADFLYAYSTAPGYYSWRNSKDGS 213 LF IQAC+G LD GI T S + D + ++IPV ADFL A+ST PGY+SWRN+ GS Sbjct: 144 LFFIQACQGDRLDGGI-TLSRTETDGSPSTSYRIPVHADFLIAFSTVPGYFSWRNTTRGS 202 Query: 214 WFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFD-ATFHAKKQIPCIVSMLTKE 272 WF+Q+LC L+ + + + +LT V +KVA +FES + D A H +KQ+PCI SMLT+ Sbjct: 203 WFMQALCEELRYAGTERDILTLLTFVCQKVALDFESNAPDSAMMHQQKQVPCITSMLTRL 262 Query: 273 LYF 275 L F Sbjct: 263 LVF 265 >2NN3-C nrPDB Length = 310 Score = 308 bits (789), Expect = 2e-84, Method: Composition-based stats. Identities = 98/243 (40%), Positives = 150/243 (61%), Gaps = 6/243 (2%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M++ G+ II N+++F + SR+GT+VD+ NL + + L ++V +L EEI Sbjct: 53 YNMNHKHRGMAIIFNHEHFDIH-SLKSRTGTNVDSDNLSKVLKTLGFKVTVFPNLKSEEI 111 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + ++ ++ DHS + +L+ GE G+++ + + +F D+C +L GKPK Sbjct: 112 NKFIQQTAEMDHSDADCLLVAVLTAGELGMLYAKDTHYKPDNLWYYFTADKCPTLAGKPK 171 Query: 157 LFIIQACRGTELDCGIETDSGVDDDMA---CHKIPVEADFLYAYSTAPGYYSWRNSKDGS 213 LF IQAC+G LD GI T S + D + ++IPV ADFL A+ST PGY+SWRN+ GS Sbjct: 172 LFFIQACQGDRLDGGI-TLSRTETDGSPSTSYRIPVHADFLIAFSTVPGYFSWRNTTRGS 230 Query: 214 WFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFD-ATFHAKKQIPCIVSMLTKE 272 WF+Q+LC L+ + + + +LT V +KVA +FES + D A H +KQ+PCI SMLT+ Sbjct: 231 WFMQALCEELRYAGTERDILTLLTFVCQKVALDFESNAPDSAMMHQQKQVPCITSMLTRL 290 Query: 273 LYF 275 L F Sbjct: 291 LVF 293 >4JJ7-A nrPDB Length = 275 Score = 301 bits (772), Expect = 1e-82, Method: Composition-based stats. Identities = 96/267 (35%), Positives = 147/267 (55%), Gaps = 24/267 (8%) Query: 27 MDSGISLDNSYKMDYPEMGLCIIINNKNFHKST-------GMTSRSGTDVDAANLRETFR 79 M +LD Y+M G C+IINN NF K+ + R+GT +DA L TF Sbjct: 1 MSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFE 60 Query: 80 NLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGP-VDLKK 138 L +E++ +D T E+I E+++ DHS F+C +LSHG++GII+GT+G + + Sbjct: 61 ELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYE 120 Query: 139 ITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG------VDDDMACHK---IPV 189 +T+ F G +C SL GKPK+F IQAC+G GI ++ ++ D++ + IP Sbjct: 121 LTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPD 180 Query: 190 EADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL-EFMHILTRVNRKVATEFE 248 EADFL +T S+RN +G+W+IQSLC L++ + + + ILT VN +V+ + Sbjct: 181 EADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNK-- 238 Query: 249 SFSFDATFHAKKQIPCIVSMLTKELYF 275 D + KQ+P L K+L F Sbjct: 239 ----DDKKNMGKQMPQPTFTLRKKLVF 261 >2AR9-A nrPDB Length = 278 Score = 276 bits (705), Expect = 8e-75, Method: Composition-based stats. Identities = 95/274 (34%), Positives = 145/274 (52%), Gaps = 42/274 (15%) Query: 34 DNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTR 93 D +Y + G C+IINN NF + +G+ +R+G+++D LR F +L + V K DLT Sbjct: 12 DLAYILSMEPCGHCLIINNVNFCRESGLRTRTGSNIDCEKLRRRFSSLHFMVEVKGDLTA 71 Query: 94 EEIVELMRDVSKEDHSKRSSFVCVLLSHGEE-------GIIFGTNG-PVDLKKITNFFRG 145 +++V + +++++DH V V+LSHG + G ++GT+G PV ++KI N F G Sbjct: 72 KKMVLALLELARQDHGALDCCVVVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVNIFNG 131 Query: 146 DRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDM----------------------- 182 C SL GKPKLF IQA G + D G E S +D Sbjct: 132 TSCPSLGGKPKLFFIQASGGEQKDHGFEVASTSPEDESPGSNPEPDATPFQEGLRTFDQL 191 Query: 183 -ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNR 241 A +P +D +YST PG+ SWR+ K GSW++++L + +Q+A + +L RV Sbjct: 192 DAISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLDDIFEQWAHSEDLQSLLLRVAN 251 Query: 242 KVATEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 V+ + KQ+PCIVSML K+L+F Sbjct: 252 AVSVK----------GIYKQMPCIVSMLRKKLFF 275 >4M9R-A nrPDB Length = 306 Score = 268 bits (685), Expect = 2e-72, Method: Composition-based stats. Identities = 89/268 (33%), Positives = 131/268 (48%), Gaps = 35/268 (13%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y+ G+C+IINN++F + M +R+GT D NL FR + Y V K++LT + Sbjct: 38 YRNFSSPRGMCLIINNEHFEQ---MPTRNGTKADKDNLTNLFRCMGYTVICKDNLTGRGM 94 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNG-PVDLKKITNFFRGDRCRSLTGKP 155 + +RD +K + S S + V+LSHGEE +I G + P+ +I + L KP Sbjct: 95 LLTIRDFAKHE-SHGDSAILVILSHGEENVIIGVDDIPISTHEIYDLLNAANAPRLANKP 153 Query: 156 KLFIIQACRGTELDCGIETDSGVD------------DDMAC---------------HKIP 188 K+ +QA RG D G VD D K P Sbjct: 154 KIVFVQASRGERRDNGFPVLDSVDGVPAFLRRGWDNRDGPLFNFLGCVRPQVQQVWRKKP 213 Query: 189 VEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFE 248 +AD L AY+T Y SWRNS GSWFIQ++C + +A ++ + +LT VN+KVA F+ Sbjct: 214 SQADILIAYATTAQYVSWRNSARGSWFIQAVCEVFSTHAKDMDVVELLTEVNKKVACGFQ 273 Query: 249 SFSFDATFHAKKQIPCIVSMLTKELYFY 276 + KQ+P + S L K+ YF+ Sbjct: 274 TSQGSNIL---KQMPEMTSRLLKKFYFW 298 >6BGQ-A nrPDB Length = 175 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 174/175 (99%), Positives = 174/175 (99%) Query: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG Sbjct: 1 MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG 60 Query: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS Sbjct: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS 120 Query: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETD 175 HGEEGIIFGTNGPVDLKKITNFFRGDRCR LTGKPKLFIIQACRGTELDCGIETD Sbjct: 121 HGEEGIIFGTNGPVDLKKITNFFRGDRCRDLTGKPKLFIIQACRGTELDCGIETD 175 >3J9K-B nrPDB Length = 450 Score = 251 bits (642), Expect = 2e-67, Method: Composition-based stats. Identities = 67/266 (25%), Positives = 118/266 (44%), Gaps = 35/266 (13%) Query: 8 VDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYP-EMGLCIIINNKNFHKSTGMTSRSG 66 VD +K + K IHG +S G +YKM G+ +++N ++ R G Sbjct: 165 VDGPEVK--KSKKIHGGDSAILG-----TYKMQSRFNRGVLLMVNIMDYPDQN--RRRIG 215 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRS-SFVCVLLSHG--- 122 + D+ +L F+ L + + ++ +++ +L+ V+ + + + FV VL++HG Sbjct: 216 AEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSV 275 Query: 123 --EEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG--- 177 +E + F VD++KI + F+ +C L KPK+ + CRG E D G + G Sbjct: 276 EGKEKVEFCDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFCRGDEYDLGHPKNQGNLM 335 Query: 178 -----------VDDDM-----ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCA 221 D +P AD L Y+ PGY + R+ GSW+IQ C Sbjct: 336 EPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQ 395 Query: 222 MLKQYADKLEFMHILTRVNRKVATEF 247 ++ +A + IL + + V + Sbjct: 396 VMADHAHDTDLEDILKKTSEAVGNKR 421 >2FP3-A nrPDB Length = 316 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 66/266 (24%), Positives = 117/266 (43%), Gaps = 35/266 (13%) Query: 8 VDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYP-EMGLCIIINNKNFHKSTGMTSRSG 66 VD +K + K IHG +S G +YKM G+ +++N ++ R G Sbjct: 31 VDGPEVK--KSKKIHGGDSAILG-----TYKMQSRFNRGVLLMVNIMDYPDQN--RRRIG 81 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRS-SFVCVLLSHG--- 122 + D+ +L F+ L + + ++ +++ +L+ V+ + + + FV VL++HG Sbjct: 82 AEKDSKSLIHLFQELNFTIFPYGNVNQDQFFKLLTMVTSSSYVQNTECFVMVLMTHGNSV 141 Query: 123 --EEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG--- 177 +E + F VD++KI + F+ +C L KPK+ + RG E D G + G Sbjct: 142 EGKEKVEFRDGSVVDMQKIKDHFQTAKCPYLVNKPKVLMFPFARGDEYDLGHPKNQGNLM 201 Query: 178 -----------VDDDM-----ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCA 221 D +P AD L Y+ PGY + R+ GSW+IQ C Sbjct: 202 EPVYTAQEEKWPDTQTEGIPSPSTNVPSLADTLVCYANTPGYVTHRDLDTGSWYIQKFCQ 261 Query: 222 MLKQYADKLEFMHILTRVNRKVATEF 247 ++ +A + IL + + V + Sbjct: 262 VMADHAHDTDLEDILKKTSEAVGNKR 287 >3E4C-A nrPDB Length = 302 Score = 227 bits (579), Expect = 3e-60, Method: Composition-based stats. Identities = 79/297 (26%), Positives = 120/297 (40%), Gaps = 36/297 (12%) Query: 2 ENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMG-LCIIINNKNFHKSTG 60 +N S S N++ + ++ + S + MD L +II N+ F Sbjct: 17 DNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFD---S 73 Query: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIV-ELMRDVSKEDHSKRSSFVCVLL 119 + R+G +VD + +NL Y V K +LT ++ EL + +H S V + Sbjct: 74 IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFM 133 Query: 120 SHG-EEGIIFGTNGP-----VDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTE------ 167 SHG EGI + + L I N C SL KPK+ IIQA RG Sbjct: 134 SHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQAARGDSPGVVWF 193 Query: 168 -------LDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLC 220 + + T +DD A K +E DF+ S+ P SWR+ GS FI L Sbjct: 194 KDSVGVSGNLSLPTTEEFEDD-AIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLI 252 Query: 221 AMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVS-MLTKELYFY 276 +++YA + I +V FSF+ + Q+P LT+ Y + Sbjct: 253 EHMQEYACSCDVEEIFRKVR---------FSFEQP-DGRAQMPTTERVTLTRCFYLF 299 >2XZT-A nrPDB Length = 149 Score = 224 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 148/149 (99%), Positives = 148/149 (99%) Query: 27 MDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVR 86 M SGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVR Sbjct: 1 MSSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVR 60 Query: 87 NKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGD 146 NKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGD Sbjct: 61 NKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGD 120 Query: 147 RCRSLTGKPKLFIIQACRGTELDCGIETD 175 RCRSLTGKPKLFIIQACRGTELDCGIETD Sbjct: 121 RCRSLTGKPKLFIIQACRGTELDCGIETD 149 >3H13-A nrPDB Length = 272 Score = 207 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 69/271 (25%), Positives = 113/271 (41%), Gaps = 39/271 (14%) Query: 19 KIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETF 78 K I SE+ + YKM +G+C+II+ G + + LR+TF Sbjct: 18 KSIQESEAFLPQSIPEERYKMKSKPLGICLIIDC------------IGNETEL--LRDTF 63 Query: 79 RNLKYEVRNKNDLTREEIVELMRDVS-KEDHSKRSSFVCVLLSHGEEGIIFG---TNGPV 134 +L YEV+ L+ I +++ + +H SFVCVL+S G ++G T+ + Sbjct: 64 TSLGYEVQKFLHLSMHGISQILGQFACMPEHRDYDSFVCVLVSRGGSQSVYGVDQTHSGL 123 Query: 135 DLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHK-------- 186 L I F GD C L GKPK+F IQ +E +E S ++ D K Sbjct: 124 PLHHIRRMFMGDSCPYLAGKPKMFFIQNYVVSEGQ--LENSSLLEVDGPAMKNVEFKAQK 181 Query: 187 -----IPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADK------LEFMHI 235 + EADF ++ TA ++ S ++Q L L+Q + +E Sbjct: 182 RGLCTVHREADFFWSLCTADMSLLEQSHSSPSLYLQCLSQKLRQERKRPLLDLHIELNGY 241 Query: 236 LTRVNRKVATEFESFSFDATFHAKKQIPCIV 266 + N +V+ + + + + KK I Sbjct: 242 MYDWNSRVSAKEKYYVWLQHTLRKKLILSYT 272 >4JB8-A nrPDB Length = 175 Score = 203 bits (517), Expect = 5e-53, Method: Composition-based stats. Identities = 79/169 (46%), Positives = 110/169 (65%), Gaps = 4/169 (2%) Query: 7 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG 66 S+ SK KN+ + I + Y M++ ++G CIIINNKNF K TGM R+G Sbjct: 11 SLFSKKKKNVTMRSIKTTRD----RVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG 66 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI 126 TD DA L + FR+L ++V ND + ++ +L++ S+EDH+ + F C+LLSHGEE + Sbjct: 67 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV 126 Query: 127 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETD 175 I+G +G +K +T FRGDRC++L KPKLF IQACRGTELD GI+ D Sbjct: 127 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQAD 175 >1I51-A nrPDB Length = 148 Score = 202 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 72/144 (50%), Positives = 99/144 (68%) Query: 32 SLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDL 91 Y M++ ++G CIIINNKNF K TGM R+GTD DA L + FR+L ++V ND Sbjct: 5 VPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDC 64 Query: 92 TREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSL 151 + ++ +L++ S+EDH+ + F C+LLSHGEE +I+G +G +K +T FRG RC++L Sbjct: 65 SCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGARCKTL 124 Query: 152 TGKPKLFIIQACRGTELDCGIETD 175 KPKLF IQACRGTELD GI+ D Sbjct: 125 LEKPKLFFIQACRGTELDDGIQAD 148 >4ZVU-A nrPDB Length = 198 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 79/169 (46%), Positives = 110/169 (65%), Gaps = 4/169 (2%) Query: 7 SVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSG 66 S+ SK KN+ + I + Y M++ ++G CIIINNKNF K TGM R+G Sbjct: 34 SLFSKKKKNVTMRSIKTTRD----RVPTYQYNMNFEKLGKCIIINNKNFDKVTGMGVRNG 89 Query: 67 TDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGI 126 TD DA L + FR+L ++V ND + ++ +L++ S+EDH+ + F C+LLSHGEE + Sbjct: 90 TDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENV 149 Query: 127 IFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETD 175 I+G +G +K +T FRGDRC++L KPKLF IQACRGTELD GI+ D Sbjct: 150 IYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQAD 198 >3KJN-A nrPDB Length = 164 Score = 202 bits (513), Expect = 2e-52, Method: Composition-based stats. Identities = 62/161 (38%), Positives = 92/161 (57%), Gaps = 8/161 (4%) Query: 25 ESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKST-------GMTSRSGTDVDAANLRET 77 E +LD Y+M G C+IINN NF K+ + R+GT +DA L T Sbjct: 4 EQDSESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTT 63 Query: 78 FRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGP-VDL 136 F L +E++ +D T E+I E+++ DHS F+C +LSHG++GII+GT+G + Sbjct: 64 FEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPI 123 Query: 137 KKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSG 177 ++T+ F G +C SL GKPK+F IQAC+G GI ++ Sbjct: 124 YELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVETD 164 >3P45-A nrPDB Length = 179 Score = 201 bits (510), Expect = 4e-52, Method: Composition-based stats. Identities = 56/140 (40%), Positives = 82/140 (58%) Query: 33 LDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLT 92 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL Sbjct: 33 PAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLK 92 Query: 93 REEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLT 152 EE++ + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL Sbjct: 93 AEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLV 152 Query: 153 GKPKLFIIQACRGTELDCGI 172 GKPK+FIIQACRG + D + Sbjct: 153 GKPKIFIIQACRGNQHDVPV 172 >3QNW-A nrPDB Length = 156 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 56/140 (40%), Positives = 82/140 (58%) Query: 33 LDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLT 92 YKMD+ G+ +I N++ F + R GT D NL F +L +EV+ NDL Sbjct: 10 PAEKYKMDHRRRGIALIFNHERFFWHLTLPERRGTCADRDNLTRRFSDLGFEVKCFNDLK 69 Query: 93 REEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLT 152 EE++ + +VS H+ FVCV LSHGE I+ + ++++ +T F+GD+C SL Sbjct: 70 AEELLLKIHEVSTVSHADADCFVCVFLSHGEGNHIYAYDAKIEIQTLTGLFKGDKCHSLV 129 Query: 153 GKPKLFIIQACRGTELDCGI 172 GKPK+FIIQACRG + D + Sbjct: 130 GKPKIFIIQACRGNQHDVPV 149 >3SIP-A nrPDB Length = 157 Score = 197 bits (500), Expect = 6e-51, Method: Composition-based stats. Identities = 50/136 (36%), Positives = 76/136 (55%), Gaps = 1/136 (0%) Query: 37 YKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEI 96 Y M + G+ +I N+++F T + SR+GT+VD NL + L +EV D ++I Sbjct: 13 YNMRHKNRGMALIFNHEHFEVPT-LKSRAGTNVDCENLTRVLKQLDFEVTVYKDCRYKDI 71 Query: 97 VELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPK 156 + + + ++HS + +LSHGE G I+ + L I +FF + C SL GKPK Sbjct: 72 LRTIEYAASQNHSDSDCILVAILSHGEMGYIYAKDTQYKLDNIWSFFTANHCPSLAGKPK 131 Query: 157 LFIIQACRGTELDCGI 172 LF IQAC+G LD G+ Sbjct: 132 LFFIQACQGDRLDGGV 147 >3RJM-A nrPDB Length = 169 Score = 178 bits (452), Expect = 2e-45, Method: Composition-based stats. Identities = 50/146 (34%), Positives = 79/146 (54%), Gaps = 2/146 (1%) Query: 30 GISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKN 89 +Y++ GL ++++N +F + RSG DVD + L F+ L Y+V Sbjct: 21 QTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLC 80 Query: 90 DLTREEIVELMRDVSK-EDHSKRSSFVCVLLSHGEEGIIFGTNGP-VDLKKITNFFRGDR 147 D T +E+ E +++ ++ H S + LLSHG EG I+G +G + L+++ F Sbjct: 81 DQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNAN 140 Query: 148 CRSLTGKPKLFIIQACRGTELDCGIE 173 C SL KPK+F IQACRG E D G++ Sbjct: 141 CPSLQNKPKMFFIQACRGDETDRGVD 166 >1RHJ-B nrPDB Length = 110 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 102/102 (100%), Positives = 102/102 (100%) Query: 176 SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI 235 SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI Sbjct: 1 SGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI 60 Query: 236 LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 277 LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH Sbjct: 61 LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH 102 >4JB8-B nrPDB Length = 105 Score = 149 bits (376), Expect = 1e-36, Method: Composition-based stats. Identities = 62/93 (66%), Positives = 74/93 (79%) Query: 183 ACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRK 242 +KIPVEADFL+AYST PGYYSWR+ GSWF+Q+LC++L+++ LE M ILTRVN + Sbjct: 3 PRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDR 62 Query: 243 VATEFESFSFDATFHAKKQIPCIVSMLTKELYF 275 VA FES S D FH KKQIPC+VSMLTKELYF Sbjct: 63 VARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 95 >6F6R-A nrPDB Length = 180 Score = 141 bits (356), Expect = 3e-34, Method: Composition-based stats. Identities = 50/174 (28%), Positives = 74/174 (42%), Gaps = 11/174 (6%) Query: 2 ENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMG-LCIIINNKNFHKSTG 60 +N S S N++ + ++ + S + MD L +II N+ F Sbjct: 2 DNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFD---S 58 Query: 61 MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIV-ELMRDVSKEDHSKRSSFVCVLL 119 + R+G +VD + +NL Y V K +LT ++ EL + +H S V + Sbjct: 59 IPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFM 118 Query: 120 SHG-EEGIIFGTNGP-----VDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTE 167 SHG EGI + + L I N C SL KPK+ IIQACRG Sbjct: 119 SHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDS 172 >3SIP-B nrPDB Length = 109 Score = 140 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 52/97 (53%), Positives = 67/97 (69%), Gaps = 1/97 (1%) Query: 180 DDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRV 239 D +KIPV ADFL AYST PG+YSWRN+ GSWF+QSLCA L +L+ + +LT V Sbjct: 2 DSSMSYKIPVHADFLIAYSTVPGFYSWRNTTRGSWFMQSLCAELAANGKRLDILTLLTFV 61 Query: 240 NRKVATEFESFSFDAT-FHAKKQIPCIVSMLTKELYF 275 ++VA +FES + D H +KQIPCI +MLT+ L F Sbjct: 62 CQRVAVDFESCTPDTPEMHQQKQIPCITTMLTRILRF 98 >3P4U-B nrPDB Length = 108 Score = 133 bits (335), Expect = 7e-32, Method: Composition-based stats. Identities = 48/97 (49%), Positives = 62/97 (63%) Query: 180 DDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRV 239 D + + +P ADFL YS A GYYS R + +GSW+IQ LC ML +Y LEF +LT V Sbjct: 1 DAASVYTLPAGADFLMCYSVAEGYYSHRETVNGSWYIQDLCEMLGKYGSSLEFTELLTLV 60 Query: 240 NRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 276 NRKV+ F D + KKQ+PC SMLTK+L+F+ Sbjct: 61 NRKVSQRRVDFCKDPSAIGKKQVPCFASMLTKKLHFF 97 >3R7N-B nrPDB Length = 112 Score = 115 bits (288), Expect = 2e-26, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 1/97 (1%) Query: 180 DDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRV 239 + + ++P +D + Y+ G + RN+K GSW+I++L + + A + +L +V Sbjct: 3 EKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKV 62 Query: 240 NRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY 276 N + + E ++ FH K++ S L + LY + Sbjct: 63 N-ALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLF 98 >3KJN-B nrPDB Length = 95 Score = 106 bits (265), Expect = 9e-24, Method: Composition-based stats. Identities = 33/90 (36%), Positives = 49/90 (54%), Gaps = 7/90 (7%) Query: 187 IPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKL-EFMHILTRVNRKVAT 245 IP EADFL +T S+RN +G+W+IQSLC L++ + + + ILT VN +V+ Sbjct: 9 IPDEADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSN 68 Query: 246 EFESFSFDATFHAKKQIPCIVSMLTKELYF 275 + D + KQ+P L K+L F Sbjct: 69 K------DDKKNMGKQMPQPTFTLRKKLVF 92 >5MMV-B nrPDB Length = 89 Score = 94.4 bits (233), Expect = 5e-20, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 11/96 (11%) Query: 182 MACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNR 241 MA K +E DF+ S+ P SWR+ GS FI L +++YA + I +V Sbjct: 1 MAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVR- 59 Query: 242 KVATEFESFSFDATFHAKKQIPCIVS-MLTKELYFY 276 FSF+ + Q+P LT+ Y + Sbjct: 60 --------FSFEQP-DGRAQMPTTERVTLTRCFYLF 86 >3V4O-A nrPDB Length = 245 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 48/244 (19%), Positives = 85/244 (34%), Gaps = 47/244 (19%) Query: 46 LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSK 105 + ++I N N+ + + + VD L R L ++V + DLT E+ + + Sbjct: 20 VALLIGNMNYREHPKLKAPL---VDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLL 76 Query: 106 EDHSKRSSFVCVLL---SHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKL----- 157 V LL HG E FG + V + N +R + C + KL Sbjct: 77 L----LDKGVYGLLYYAGHGYEN--FGNSFMVPVDA-PNPYRSENCLCVQNILKLMQEKE 129 Query: 158 -----FIIQACRG-TELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKD 211 F++ CR + D I + V A+ ++ Y+T G ++ Sbjct: 130 TGLNVFLLDMCRKRNDYDDTIPILDA---------LKVTANIVFGYATCQGAEAFEIQHS 180 Query: 212 G---SWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSM 268 G F++ L L + + +L V + KQ I S Sbjct: 181 GLANGIFMKFLKDRLLE---DKKITVLLDEVAEDMGK--------CHLTKGKQALEIRSS 229 Query: 269 LTKE 272 L+++ Sbjct: 230 LSEK 233 >3V4L-A nrPDB Length = 396 Score = 35.4 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 36/171 (21%), Positives = 63/171 (36%), Gaps = 33/171 (19%) Query: 46 LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSK 105 + ++I N ++ + + + VD L R L ++V + DLT E+ + + Sbjct: 19 VALLIGNMSYWEHPKLKAPL---VDVYELTNLLRQLDFKVVSLLDLTEYEMCNAVDEFLL 75 Query: 106 EDHSKRSSFVCVLL---SHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKL----- 157 V LL HG E FG + V + N +R + C + KL Sbjct: 76 L----LDKGVYGLLYYAGHGYEN--FGNSFMVPVDA-PNPYRSENCLCVQNILKLMQEKE 128 Query: 158 -----FIIQACRG-TELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPG 202 F++ CR + D I + V A+ ++ Y+T G Sbjct: 129 TGLNVFLLDMCRKRNDYDDTIPILDA---------LKVTANIVFGYATCQG 170 >1WNH-A nrPDB Length = 225 Score = 28.5 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 24/69 (34%), Gaps = 2/69 (2%) Query: 167 ELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQY 226 L +E D+ L + GY W+NS + +W+ +KQ Sbjct: 115 SLKRPLEAQDIPDNFGNVSPQMKPVQHLAWVAC--GYVMWQNSTEDTWYKMLKIQTVKQV 172 Query: 227 ADKLEFMHI 235 +F+ + Sbjct: 173 QRNDDFIEL 181 >5FM1-B nrPDB Length = 846 Score = 28.5 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 21/46 (45%) Query: 77 TFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHG 122 +++L Y+V L + + + E+ ++FV L+S G Sbjct: 230 LYQSLGYKVEKFRMLNISPMKKALIIEISEELQNYTAFVNNLVSSG 275 >6FAK-A nrPDB Length = 586 Score = 27.3 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 10/73 (13%) Query: 40 DYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLR--------ETFRNLKYEV-RNKND 90 PE G CII +NK+ + ++ R G D+ N+ F +E R D Sbjct: 285 KIPERGQCIINSNKD-DRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSRRHPD 343 Query: 91 LTREEIVELMRDV 103 L+ E++ +++ Sbjct: 344 LSIPELLRIVQIY 356 >2F31-A nrPDB Length = 233 Score = 27.3 bits (59), Expect = 7.6, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 29/66 (43%) Query: 59 TGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVL 118 T + + G L L + V +++L R + ++++++ + ++ +CV Sbjct: 163 TSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENEDMKVQLCVF 222 Query: 119 LSHGEE 124 G+E Sbjct: 223 DEQGDE 228 >2BAP-B nrPDB Length = 317 Score = 27.0 bits (58), Expect = 8.5, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 29/66 (43%) Query: 59 TGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVL 118 T + + G L L + V +++L R + ++++++ + ++ +CV Sbjct: 163 TSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENEDMKVQLCVF 222 Query: 119 LSHGEE 124 G+E Sbjct: 223 DEQGDE 228 >1Z2C-B nrPDB Length = 383 Score = 27.0 bits (58), Expect = 9.1, Method: Composition-based stats. Identities = 11/66 (16%), Positives = 29/66 (43%) Query: 59 TGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVL 118 T + + G L L + V +++L R + ++++++ + ++ +CV Sbjct: 229 TSIALKVGCLQLINALITPAEELDFRVHIRSELMRLGLHQVLQELREIENEDMKVQLCVF 288 Query: 119 LSHGEE 124 G+E Sbjct: 289 DEQGDE 294 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.134 0.357 Lambda K H 0.267 0.0409 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,838,364 Number of Sequences: 36641 Number of extensions: 371439 Number of successful extensions: 1131 Number of sequences better than 10.0: 46 Number of HSP's better than 10.0 without gapping: 83 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 950 Number of HSP's gapped (non-prelim): 101 length of query: 277 length of database: 10,336,785 effective HSP length: 96 effective length of query: 181 effective length of database: 6,819,249 effective search space: 1234284069 effective search space used: 1234284069 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.0 bits)