BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P41921 (483 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2HQM-A nrPDB 963 0.0 6N7F-A nrPDB 442 e-124 2AAQ-A nrPDB 430 e-121 2R9Z-A nrPDB 426 e-120 5VDN-A nrPDB 423 e-118 5U1O-A nrPDB 422 e-118 5V36-A nrPDB 415 e-116 1GEU-A nrPDB 411 e-115 6B4O-A nrPDB 386 e-107 6DU7-A nrPDB 369 e-102 1ONF-A nrPDB 328 4e-90 1ZDL-A nrPDB 276 1e-74 3O0H-A nrPDB 276 1e-74 2X8H-A nrPDB 274 7e-74 4LA1-A nrPDB 261 5e-70 4B1B-A nrPDB 256 2e-68 2WOV-A nrPDB 254 7e-68 4DNA-A nrPDB 252 3e-67 2NVK-X nrPDB 251 4e-67 2YAU-A nrPDB 246 1e-65 2CFY-A nrPDB 244 4e-65 4KPR-E nrPDB 244 5e-65 4NEW-A nrPDB 243 1e-64 5W1J-A nrPDB 243 2e-64 1FEC-A nrPDB 234 9e-62 5X1Y-B nrPDB 206 2e-53 1EBD-A nrPDB 193 1e-49 5U8W-A nrPDB 184 1e-46 2EQ6-A nrPDB 182 4e-46 5TR3-A nrPDB 182 4e-46 3LAD-A nrPDB 180 2e-45 6BZ0-A nrPDB 171 5e-43 3URH-A nrPDB 167 8e-42 6CMZ-A nrPDB 167 9e-42 1DXL-A nrPDB 167 1e-41 1V59-A nrPDB 161 6e-40 2YQU-A nrPDB 160 2e-39 4JDR-A nrPDB 158 4e-39 5J5Z-A nrPDB 158 6e-39 6AON-A nrPDB 157 1e-38 4YWO-A nrPDB 150 9e-37 1LVL-A nrPDB 150 2e-36 2QAE-A nrPDB 149 3e-36 3II4-A nrPDB 134 8e-32 1ZK7-A nrPDB 126 2e-29 3L8K-A nrPDB 111 6e-25 3IC9-A nrPDB 108 3e-24 1XDI-A nrPDB 100 2e-21 1OJT-A nrPDB 100 3e-21 5U25-A nrPDB 98 1e-20 3Q6J-A nrPDB 92 7e-19 2BC1-A nrPDB 60 3e-09 3ICS-A nrPDB 54 1e-07 3IWA-A nrPDB 54 1e-07 2CDU-A nrPDB 53 2e-07 5ER0-A nrPDB 52 7e-07 4FX9-A nrPDB 47 1e-05 3NTA-A nrPDB 47 2e-05 1YQZ-A nrPDB 47 2e-05 3CGD-A nrPDB 47 3e-05 3OC4-A nrPDB 46 3e-05 2YVG-A nrPDB 44 1e-04 3AB1-A nrPDB 42 6e-04 1Q1R-A nrPDB 41 0.001 5JCN-A nrPDB 40 0.002 4YRY-B nrPDB 40 0.003 1NHQ-A nrPDB 39 0.004 1F6M-A nrPDB 39 0.007 3LXD-A nrPDB 37 0.013 1NAA-A nrPDB 37 0.015 4GCM-A nrPDB 37 0.018 3BHF-A nrPDB 37 0.024 5UWY-A nrPDB 37 0.028 3MJ4-A nrPDB 37 0.028 2V3B-A nrPDB 36 0.031 2ZBW-A nrPDB 36 0.046 5MJK-A nrPDB 35 0.058 1ZOV-A nrPDB 34 0.18 4YNU-A nrPDB 33 0.19 3FG2-P nrPDB 33 0.26 4ZN0-A nrPDB 33 0.27 5KVH-A nrPDB 33 0.28 4MO2-B nrPDB 33 0.32 2BXR-A nrPDB 33 0.33 6CR0-A nrPDB 33 0.36 4XRR-A nrPDB 33 0.37 5JFC-L nrPDB 33 0.40 3ATQ-A nrPDB 33 0.40 2VVL-G nrPDB 32 0.44 2VHY-A nrPDB 32 0.44 5HIW-A nrPDB 32 0.53 3NK2-X nrPDB 32 0.66 3IH9-A nrPDB 32 0.66 6ACQ-A nrPDB 32 0.67 5USX-A nrPDB 32 0.72 3Q9T-A nrPDB 32 0.79 5YGQ-A nrPDB 32 0.82 5VJ7-A nrPDB 32 0.86 4Y0E-A nrPDB 31 0.93 5MAC-A nrPDB 31 0.99 5BR7-A nrPDB 31 1.1 1O5W-A nrPDB 31 1.1 3F8P-A nrPDB 31 1.1 3ABT-A nrPDB 30 1.6 2Q7V-A nrPDB 30 1.9 5UTH-A nrPDB 30 2.1 4KUG-A nrPDB 30 2.2 5MOG-A nrPDB 30 2.3 1I8T-A nrPDB 30 2.6 5U63-A nrPDB 30 2.7 5NCC-A nrPDB 30 2.7 4A7P-A nrPDB 30 2.7 5L3D-A nrPDB 30 2.8 1AHW-A nrPDB 30 3.0 3CR3-A nrPDB 29 3.8 1E3W-A nrPDB 29 4.4 1XTY-A nrPDB 29 5.0 3BI4-A nrPDB 29 5.1 1REO-A nrPDB 28 6.3 3IHG-A nrPDB 28 6.4 3K30-A nrPDB 28 6.8 5EZ7-A nrPDB 28 7.1 3OZ2-A nrPDB 28 7.9 1F8S-A nrPDB 28 7.9 4C3X-A nrPDB 28 7.9 3LLV-A nrPDB 28 8.6 3KVE-A nrPDB 28 8.6 >2HQM-A nrPDB Length = 479 Score = 963 bits (2489), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/470 (99%), Positives = 468/470 (99%) Query: 14 IRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMW 73 + MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMW Sbjct: 2 VEFMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMW 61 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD Sbjct: 62 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 121 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL 193 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL Sbjct: 122 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL 181 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI Sbjct: 182 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 241 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH Sbjct: 242 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 301 Query: 314 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP 373 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP Sbjct: 302 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP 361 Query: 374 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 433 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE Sbjct: 362 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 421 Query: 434 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR Sbjct: 422 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 471 >6N7F-A nrPDB Length = 453 Score = 442 bits (1138), Expect = e-124, Method: Compositional matrix adjust. Identities = 225/462 (48%), Positives = 313/462 (67%), Gaps = 18/462 (3%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV- 82 YDY+VIGGGS G+ASA RAA +GAK LL E K +GGTCVN+GCVPKKVMWY + +A + Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILG 67 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 ++A +YG D + F++ + K R AY+ R++ Y++ E+ VD ++ +A F Sbjct: 68 TYAKDYGF------DFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFK 121 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVV 202 VE+ ++Y+A HIL+ATGG +FP+ I G + G SDGFF L+E PK+ V Sbjct: 122 DAHTVEI-----AGQLYTAPHILIATGGHPVFPD-IEGAQYGISSDGFFALDEVPKRTAV 175 Query: 203 VGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIV 262 VGAGYI +ELAGV H LGS+T L IR + LR FD+ I + + D G +H +++ Sbjct: 176 VGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVA 235 Query: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEY 321 KV KN + + L +++ D + ++ VD+LIW IGRK +L G + G+ LN I D Y Sbjct: 236 KVVKNTD-ESLTLYLKDGQEVE-VDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAY 293 Query: 322 QNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPE 381 +NT+V IY++GDV GK+ LTPVA+AAGR+LS RLF + ++KLDY+NV +VIFSHP Sbjct: 294 ENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKT--DEKLDYQNVATVIFSHPV 351 Query: 382 AGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIV 441 GS+G+SE+ A+++YG+E +K Y S+FT+M+ A+ + + P K+V G EK+VGLH + Sbjct: 352 IGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGI 411 Query: 442 GDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 G E++QGF VAIKMGATKADFDN VAIHPT +EE VTMR Sbjct: 412 GYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 453 >2AAQ-A nrPDB Length = 479 Score = 430 bits (1105), Expect = e-121, Method: Compositional matrix adjust. Identities = 240/473 (50%), Positives = 307/473 (64%), Gaps = 28/473 (5%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 YDYLVIGGGSGG+ASARRAA GA+ +VE+ LGGTCVNVGCVPKKVMW + + + Sbjct: 22 YDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMH 81 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 +YG FNW K+KRDAYV RLN IYQ NL K ++++ G A F Sbjct: 82 DHADYGFPSC------EGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTS 135 Query: 144 DG--NVEVQKRDNTTEVYSANHILVATGGKAIFP--ENIPGFELGTDSDGFFRLEEQPKK 199 D +EV + Y+A HIL+ATGG P IPG LG SDGFF+LEE P + Sbjct: 136 DPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGR 190 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V+VGAGYI +E+AG+ LGS+T L+IR + VLR FD I T+ G+ V K S Sbjct: 191 SVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFS 250 Query: 260 KIVKVEKNVETDKLKIHMNDS--------KSIDDVDELIWTIGRKSHLGMGSEN-VGIKL 310 ++ +V+K + L++ M + I DVD L+W IGR + S N +GI+ Sbjct: 251 QVKEVKKTL--SGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQT 308 Query: 311 NSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYE 370 + II DE+QNTNV IY++GDV GK LTPVAIAAGRKL++RLF E + KLDY Sbjct: 309 DDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLF--EYKEDSKLDYN 366 Query: 371 NVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAG 430 N+P+V+FSHP G++G++E EAI KYG EN+K Y++ FT MY+A+ K+ K+VCA Sbjct: 367 NIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCAN 426 Query: 431 PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 EKVVG+H+ G E+LQGF VA+KMGATKADFDN VAIHPTS+EELVT+R Sbjct: 427 KEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 479 >2R9Z-A nrPDB Length = 463 Score = 426 bits (1096), Expect = e-120, Method: Compositional matrix adjust. Identities = 214/464 (46%), Positives = 303/464 (65%), Gaps = 18/464 (3%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 80 T+H+D + IGGGSGG+A A +AA++G + L+E+KALGGTCVNVGCVPKKVMWYAS LA Sbjct: 2 TQHFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKALGGTCVNVGCVPKKVMWYASHLAE 61 Query: 81 RVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWAR 140 V A +G+ + T +WP RD Y+ +N + +E+ + V G AR Sbjct: 62 AVRDAPGFGVQAS------GGTLDWPRLVAGRDRYIGAINSFWDGYVERLGITRVDGHAR 115 Query: 141 FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKV 200 F +EV+ + SA+HI++ATGG+ I P +PG ELG SDGFF L++QPK+V Sbjct: 116 FVDAHTIEVEGQR-----LSADHIVIATGGRPIVP-RLPGAELGITSDGFFALQQQPKRV 169 Query: 201 VVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSK 260 ++GAGYIGIELAG+ GSE +V + +L +FD + T+ ++ +GI H Sbjct: 170 AIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHLEFA 229 Query: 261 IVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIAD 319 + +E++ + L D ++ D +IW +GR + +G E GI++ S+ + D Sbjct: 230 VAALERDAQGTTLV--AQDGTRLEGFDSVIWAVGRAPNTRDLGLEAAGIEVQSNGMVPTD 287 Query: 320 EYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSH 379 YQNTNVP +Y+LGD+ G+ +LTPVAIAAGR+L+ RLF + R KLDY+N+P+V+F+H Sbjct: 288 AYQNTNVPGVYALGDITGRDQLTPVAIAAGRRLAERLFDGQSER--KLDYDNIPTVVFAH 345 Query: 380 PEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLH 439 P +G+SE EA E+ G + + VY + FT M YA+ T K+VCAGP ++VVG+H Sbjct: 346 PPLSKVGLSEPEARERLG-DVLTVYETSFTPMRYALNEHGPKTAMKLVCAGPEQRVVGVH 404 Query: 440 IVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 ++GD + E+LQGF VA+KMGATKADFDN VAIHP SAEELVT++ Sbjct: 405 VIGDGADEMLQGFAVAVKMGATKADFDNTVAIHPGSAEELVTLK 448 >5VDN-A nrPDB Length = 463 Score = 423 bits (1087), Expect = e-118, Method: Compositional matrix adjust. Identities = 236/465 (50%), Positives = 303/465 (65%), Gaps = 18/465 (3%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 80 TKHYDYL IGGGSGG+AS RAA YG K L+EAK LGGTCVNVGCVPKKVMW+A+ +A Sbjct: 15 TKHYDYLAIGGGSGGIASINRAAMYGKKCALIEAKQLGGTCVNVGCVPKKVMWHAAQIAE 74 Query: 81 RVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA 139 + + +YG D F+W + R AY+ R++ Y++ L KVDV+ G+A Sbjct: 75 AIHLYGPDYGF------DTTVNHFDWKKLIANRTAYIDRIHQSYERGLGNNKVDVIQGFA 128 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKK 199 RF VEV E +A+HIL+ATGG+ P+ IPG E G DSDGFF L+E PK+ Sbjct: 129 RFVDAHTVEVNG-----ETITADHILIATGGRPSHPD-IPGAEYGIDSDGFFELDEMPKR 182 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V VVGAGYI +E+AGV +GLG+ETHL +R LR FD I T+ + EG +H S Sbjct: 183 VAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLHTES 242 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIA 318 V KN + L + + + + VD LIW IGR+ + G+K N I Sbjct: 243 VPKAVIKNAD-GSLTLQLENGTEVT-VDHLIWAIGREPATDNLNLSVTGVKTNDKGYIEV 300 Query: 319 DEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFS 378 D++QNTNV IY++GD G VELTPVA+AAGR+LS RLF + ++ LDY N+P+V+FS Sbjct: 301 DKFQNTNVKGIYAVGDNTGVVELTPVAVAAGRRLSERLFNNKP--DEHLDYSNIPTVVFS 358 Query: 379 HPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 HP G+IG++E +A EK+G + +KVY S FTAMY A+ + P R K+VC G EK+VG+ Sbjct: 359 HPPIGTIGLTEPQAREKFGDDQVKVYTSSFTAMYSAVTQHRQPCRMKLVCVGAEEKIVGI 418 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 H +G EILQGF VA+KMGATK DFDN VAIHPT+AEE VTMR Sbjct: 419 HGIGFGMDEILQGFAVAMKMGATKKDFDNTVAIHPTAAEEFVTMR 463 >5U1O-A nrPDB Length = 458 Score = 422 bits (1086), Expect = e-118, Method: Compositional matrix adjust. Identities = 238/472 (50%), Positives = 318/472 (67%), Gaps = 22/472 (4%) Query: 15 RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWY 74 + M+T H+DY+ IGGGSGG+ASA RAA YGAK L+EA+ LGGTCVNVGCVPKKVMW+ Sbjct: 6 KVMAT---HFDYICIGGGSGGIASANRAAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWH 62 Query: 75 ASDLATRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 + +A ++ +A +YG D + F+W + + R AY+ R++ Y + L KV+ Sbjct: 63 GAQIAEAMNLYAEDYGF------DVDVKGFDWSKLVESRQAYIGRIHQSYDRVLGNNKVN 116 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL 193 V+ G+A+F + VEV E Y+A+HIL+A GG+ P NIPG E G DS+GFF L Sbjct: 117 VIKGFAKFVDEKTVEVNG-----EHYTADHILIAVGGRPTIP-NIPGAEYGIDSNGFFDL 170 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 EQPK+V VVGAGYI +E+AGV H LG+ETHL +R E+ LR FD I +T+ + EG Sbjct: 171 AEQPKRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGP 230 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNS 312 +H S +V K + L +H+ + +S +VD+LIW IGR + + G+ N Sbjct: 231 TLHTHSVPKEVVKEAD-GSLTLHLENGES-QNVDQLIWAIGRHPATDAINLASTGVATNE 288 Query: 313 HDQIIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYEN 371 I DEYQ TNV IY +GD++ G +ELTPVA+ AGR+LS RLF + N K+DY+ Sbjct: 289 KGYIKVDEYQETNVKGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKP--NAKMDYDL 346 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 VP+V+FSHP G+IG++ +EA EKYGK+NIKVY S FTAMY A+ + P + K+VCAG Sbjct: 347 VPTVVFSHPPIGTIGLTTQEAEEKYGKDNIKVYTSGFTAMYTAVTKHRQPCKMKLVCAGE 406 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 E VVGLH +G + E++QGFGVA+KMGATKADFD+ VAIHPT +EE VTMR Sbjct: 407 EETVVGLHGIGFTVDEMIQGFGVAMKMGATKADFDSVVAIHPTGSEEFVTMR 458 >5V36-A nrPDB Length = 453 Score = 415 bits (1066), Expect = e-116, Method: Compositional matrix adjust. Identities = 233/465 (50%), Positives = 309/465 (66%), Gaps = 18/465 (3%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 80 TK YDY+VIGGGSGG+ASA RAA +GAK +L E K +GGTCVNVGCVPKKVMWY + +A Sbjct: 5 TKQYDYIVIGGGSGGIASANRAAMHGAKVILFEGKQVGGTCVNVGCVPKKVMWYGAQVAE 64 Query: 81 RVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA 139 ++ +A +YG D F++ KQ R AY+ R++ Y++ + V+ V+G+A Sbjct: 65 TINNYAADYGF------DVTTQAFHFDVLKQNRQAYIDRIHDSYERGFDSNGVERVYGYA 118 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKK 199 F VEV E Y+A HIL+ATGG A+ P+ IPG E G SDGFF L+ PK+ Sbjct: 119 TFVDAHTVEVAG-----EHYTAPHILIATGGHALLPD-IPGSEYGITSDGFFELDAIPKR 172 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 VVGAGYI +E++G+ H LGSETHL +R + LRKFD+ I T+ D K+G ++H S Sbjct: 173 TAVVGAGYIAVEISGILHALGSETHLFVRRDRPLRKFDKEIVGTLVDEMKKDGPHLHTFS 232 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIA 318 +V KN + I N + VD LIW IGR ++ G E G+ L+S I Sbjct: 233 VPKEVIKNTDNSLTLILENGEEYT--VDTLIWAIGRAANTKGFNLEVTGVTLDSRGFIAT 290 Query: 319 DEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFS 378 D ++NTNV +Y+LGDV GK+ELTPVA+ AGR+LS RLF + K+DY++V +VIFS Sbjct: 291 DAFENTNVEGLYALGDVNGKLELTPVAVKAGRQLSERLFNHKP--QAKMDYKDVATVIFS 348 Query: 379 HPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 HP GSIG+SE+ A+++YG+EN+ VY S FT+MY A+ S + + K+V G +EK+VGL Sbjct: 349 HPVIGSIGLSEEAALDQYGEENVTVYRSTFTSMYTAVTSHRQACKMKLVTVGEDEKIVGL 408 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 H +G E++QGF VAIKMGATKADFDN VAIHPT +EE VTMR Sbjct: 409 HGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 453 >1GEU-A nrPDB Length = 450 Score = 411 bits (1057), Expect = e-115, Method: Compositional matrix adjust. Identities = 230/465 (49%), Positives = 303/465 (65%), Gaps = 18/465 (3%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 80 TKHYDY+ IGGGSGG+AS RAA YG K L+EAK LGGTCVNVGCVPKKVMW+A+ + Sbjct: 2 TKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIRE 61 Query: 81 RVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA 139 + + +YG D FNW R AY+ R++ Y+ L K VDV+ G+A Sbjct: 62 AIHMYGPDYGF------DTTINKFNWETLIASRTAYIDRIHTSYENVLGKNNVDVIKGFA 115 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKK 199 RF +EV E +A+HIL+ATGG+ P+ IPG E G DSDGFF L P++ Sbjct: 116 RFVDAKTLEVNG-----ETITADHILIATGGRPSHPD-IPGVEYGIDSDGFFALPALPER 169 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V VVGAGYIG+EL GV +GLG++THL + L FD I T+ + EG +H + Sbjct: 170 VAVVGAGYIGVELGGVINGLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEGPQLHTNA 229 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRK-SHLGMGSENVGIKLNSHDQIIA 318 V KN + L + + D +S + VD LIW IGR+ ++ + E G+K N I+ Sbjct: 230 IPKAVVKNTD-GSLTLELEDGRS-ETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIVV 287 Query: 319 DEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFS 378 D+YQNTN+ IY++GD G VELTPVA+AAGR+LS RLF + ++ LDY N+P+V+FS Sbjct: 288 DKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKP--DEHLDYSNIPTVVFS 345 Query: 379 HPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 HP G++G++E +A E+YG + +KVY S FTAMY A+ + + P R K+VC G EK+VG+ Sbjct: 346 HPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGSEEKIVGI 405 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 H +G E+LQGF VA+KMGATK DFDN VAIHPT+AEE VTMR Sbjct: 406 HGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR 450 >6B4O-A nrPDB Length = 452 Score = 386 bits (991), Expect = e-107, Method: Compositional matrix adjust. Identities = 218/470 (46%), Positives = 300/470 (63%), Gaps = 22/470 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S K YDY+VIGGGSGG+ASA RA +GA LL+E +GGTCVNVGCVPKKVMW AS Sbjct: 1 SNAMKTYDYIVIGGGSGGIASANRAGMHGANVLLIEGNEIGGTCVNVGCVPKKVMWQASS 60 Query: 78 LATRVSHANE-YGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 + + YG D E F++ + + R+ Y+ L+G Y + L+ ++ + Sbjct: 61 MMEMMERDTAGYGF------DVEIKNFSFKQLVENREKYIDFLHGAYNRGLDSNNIERIH 114 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPEN--IPGFELGTDSDGFFRLE 194 G+A F + +EV N TE Y+A HIL+ATGG+ P+ IPG E DS+GFF LE Sbjct: 115 GYATFTGEQTIEV----NGTE-YTAPHILIATGGR---PKKLGIPGEEYALDSNGFFALE 166 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 E PK+VV VGAGYI ELAG HGLG+ETH R E LR FD+ + + + Y + G+ Sbjct: 167 EMPKRVVFVGAGYIAAELAGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMGMQ 226 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSH 313 +H + K+EK + + + I + +SI D +I+ GR+ + +G EN + L+ Sbjct: 227 IHPNATPAKIEKTAQNEYV-ITFENGESIT-TDAVIFGTGRQPNTDQLGLENTKVALDEK 284 Query: 314 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP 373 + D++QNT IY++GDV+GK++LTPVAIAAGR+LS RLF + + LDY VP Sbjct: 285 GYVKVDKFQNTTQNGIYAVGDVIGKIDLTPVAIAAGRRLSERLFNGQT--DLYLDYNLVP 342 Query: 374 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 433 +V+F+HP +IG++EK A+E+YG++ +K+Y S FT MY+A+ + K++C G E Sbjct: 343 TVVFTHPPVATIGLTEKAALEEYGEDQVKIYRSSFTPMYFALGEYRQKCDMKLICVGKEE 402 Query: 434 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 K+VGLH +G E+LQGF VAIKMGATKADFDN VAIHPT +EE VTMR Sbjct: 403 KIVGLHGIGIGVDEMLQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 452 >6DU7-A nrPDB Length = 448 Score = 369 bits (948), Expect = e-102, Method: Compositional matrix adjust. Identities = 199/445 (44%), Positives = 268/445 (60%), Gaps = 19/445 (4%) Query: 41 RAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHANE-YGLYQNLPLDKE 99 RA +GA+ ++E K LGGTCVNVGCVPKK+MWY + +A E YG Sbjct: 21 RAGEHGAQAAVIEEKKLGGTCVNVGCVPKKIMWYGAQIAETFHQFGEDYGFKTT------ 74 Query: 100 HLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVY 159 L F++ ++ R++Y+ R Y + ++ VD++ G A F V V E+ Sbjct: 75 DLNFDFATLRRNRESYIDRARSSYDGSFKRNGVDLIEGHAEFVDSHTVSVNG-----ELI 129 Query: 160 SANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL 219 A HI++ATG P NIPG ELG SD F EE P+ V ++GAGYI +ELAGV H Sbjct: 130 RAKHIVIATGAHPSIP-NIPGAELGGSSDDVFAWEELPESVAILGAGYIAVELAGVLHTF 188 Query: 220 GSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMND 279 G +T L +R + LR FD I + + + +H VK+EK TD + IH D Sbjct: 189 GVKTDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTHKVPVKLEKT--TDGITIHFED 246 Query: 280 SKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGK 338 S ++IW GR+ ++ G+ E G+ LN I DEYQNT V IY+LGDV G+ Sbjct: 247 GTS-HTASQVIWATGRRPNVKGLQLEKAGVTLNERGFIQVDEYQNTVVEGIYALGDVTGE 305 Query: 339 VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGK 398 ELTPVAI AGR LS RLF + K+DY +P+V+FSHP G++G++E++AI++YG+ Sbjct: 306 KELTPVAIKAGRTLSERLFNGKT--TAKMDYSTIPTVVFSHPAIGTVGLTEEQAIKEYGQ 363 Query: 399 ENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKM 458 + IKVY S F +MY A + +R+K++ AG EKVVGLH +G E++QGF VAIKM Sbjct: 364 DQIKVYKSSFASMYSACTRNRQESRFKLITAGSEEKVVGLHGIGYGVDEMIQGFAVAIKM 423 Query: 459 GATKADFDNCVAIHPTSAEELVTMR 483 GATKADFD VAIHPTS+EE VTMR Sbjct: 424 GATKADFDATVAIHPTSSEEFVTMR 448 >1ONF-A nrPDB Length = 500 Score = 328 bits (840), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 203/511 (39%), Positives = 302/511 (59%), Gaps = 68/511 (13%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 YD +VIGGGSGG+A+ARRAA + AK LVE LGGTCVNVGCVPKK+M+ A+ + + Sbjct: 3 YDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDILE 62 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 ++ YG +FN P ++RD Y+ RLN IY++NL K+KVD+ G A F Sbjct: 63 NSRHYGF-------DTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLS 115 Query: 144 DGNVEVQ-KRDNTT--------EVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLE 194 + + ++ +DN E+ +IL+A G K +FP + G E SD FF ++ Sbjct: 116 ENRILIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPP-VKGIENTISSDEFFNIK 174 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 E KK+ +VG+GYI +EL V LG ++++ RG +LRKFDE + N + + K IN Sbjct: 175 ES-KKIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNIN 233 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGI-KLN-- 311 + + +V+++K V L IH++D + + D +I+ +GR +EN+ + KLN Sbjct: 234 IVTFADVVEIKK-VSDKNLSIHLSDGRIYEHFDHVIYCVGRSP----DTENLKLEKLNVE 288 Query: 312 -SHDQIIADEYQNTNVPNIYSLGD----------------------------------VV 336 +++ I+ DE Q T+V NIY++GD + Sbjct: 289 TNNNYIVVDENQRTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIF 348 Query: 337 GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKY 396 V+LTPVAI AGR L++RLF + K +Y+ +P+VIFSHP G+IG+SE+ AI+ Y Sbjct: 349 YNVQLTPVAINAGRLLADRLFLK---KTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIY 405 Query: 397 GKENIKVYNSKFTAMYYAMLS----EKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGF 452 GKEN+K+Y SKFT +++++ K T K+VC G +E + GLHI+G ++ EI+QGF Sbjct: 406 GKENVKIYESKFTNLFFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGF 465 Query: 453 GVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 VA+KM ATK DFD + IHPT+AEE +T++ Sbjct: 466 AVALKMNATKKDFDETIPIHPTAAEEFLTLQ 496 >1ZDL-A nrPDB Length = 517 Score = 276 bits (707), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 169/480 (35%), Positives = 262/480 (54%), Gaps = 29/480 (6%) Query: 22 KHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVM 72 + +D LVIGGGSGG+A A+ AA G K + + LGGTCVNVGC+PKK+M Sbjct: 31 QSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLM 90 Query: 73 WYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 A+ L + A+ YG P+ NW + +V LN ++ L+ KV Sbjct: 91 HQAALLGGMIRDAHHYGWEVAQPVQH-----NWKTMAEAVQNHVKSLNWGHRVQLQDRKV 145 Query: 133 DVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFF 191 A F + V + + SA HI++ATGG+ +P + G E G SD F Sbjct: 146 KYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIF 205 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 L+E P K +VVGA Y+ +E AG G+G +T +++R LR FD+ + + +T+H Sbjct: 206 WLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMR-SIPLRGFDQQMSSLVTEHMESH 264 Query: 252 GINVHKLSKIVKVEKNVETDKLKI----HMNDSKSIDDVDELIWTIGRKSHL-GMGSENV 306 G K ++K + T++L++ H + + D ++W IGR + E Sbjct: 265 GTQFLKGCVPSHIKK-LPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKA 323 Query: 307 GIKLNSHDQ-IIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRN 364 GI N +Q II D + T+VP+IY++GDV G+ ELTP AI AG+ L+ RLFG + Sbjct: 324 GISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKS---S 380 Query: 365 DKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY 424 +DY NVP+ +F+ E G +G+SE+EA+ +G+E+++VY++ + + + + + Y Sbjct: 381 TLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCY 440 Query: 425 -KIVCAG-PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 K+VC P + V+GLH +G ++ E+ QGF + IK GA+ A V IHPT +EE+V + Sbjct: 441 IKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKL 500 >3O0H-A nrPDB Length = 484 Score = 276 bits (706), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 162/468 (34%), Positives = 259/468 (55%), Gaps = 22/468 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S + +D VIG GSGGV +AR A + G + + E +GGTCV GCVPKK+ +YAS Sbjct: 21 SMGSFDFDLFVIGSGSGGVRAARLAGALGKRVAIAEEYRIGGTCVIRGCVPKKLYFYASQ 80 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 A S + +G P+ FNW + ++ + RL G+Y++ L+ V + Sbjct: 81 YAQEFSKSIGFGWKYADPI------FNWEKLVAAKNKEISRLEGLYREGLQNSNVHIYES 134 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQP 197 A F + +E+ T E SA IL+ATG K + I G +L S+ F LE+ P Sbjct: 135 RAVFVDEHTLELSV---TGERISAEKILIATGAKIVSNSAIKGSDLCLTSNEIFDLEKLP 191 Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K +V+VG GYIG+E A +FHGLG +T L+ RG+ +LR FD ++ + D V +GI++ Sbjct: 192 KSIVIVGGGYIGVEFANIFHGLGVKTTLLHRGDLILRNFDYDLRQLLNDAMVAKGISIIY 251 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR-KSHLGMGSENVGIKLNSHDQI 316 + + +V+ + + + + ++I D ++ GR + G+G E G+K+N + Sbjct: 252 EATVSQVQST--ENCYNVVLTNGQTI-CADRVMLATGRVPNTTGLGLERAGVKVNEFGAV 308 Query: 317 IADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKL--DYENVPS 374 + DE TNV +I+++GDV G ++LTPVAI F F N DY+ + + Sbjct: 309 VVDEKMTTNVSHIWAVGDVTGHIQLTPVAIH-----DAMCFVKNAFENTSTTPDYDLITT 363 Query: 375 VIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEK 434 +FS PE G++G+SE++A+ +Y + +++Y + F M + K+V G + Sbjct: 364 AVFSQPEIGTVGLSEEDALHRY--KRVEIYRTVFRPMRNVLSGSPEKMFMKLVVDGESRI 421 Query: 435 VVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 VVG H++G+++ EI Q G+++K TK FD +A+HPT +EELVTM Sbjct: 422 VVGAHVLGENAGEIAQLIGISLKGKLTKDIFDKTMAVHPTMSEELVTM 469 >2X8H-A nrPDB Length = 598 Score = 274 bits (700), Expect = 7e-74, Method: Compositional matrix adjust. Identities = 178/483 (36%), Positives = 271/483 (56%), Gaps = 33/483 (6%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWY 74 YD +VIGGGSGG+A+ + AA YGAKT +++ LGGTCVNVGC+PKK+M Sbjct: 108 YDLIVIGGGSGGLAAGKEAAKYGAKTAVLDYVEPTPIGTTWGLGGTCVNVGCIPKKLMHQ 167 Query: 75 ASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134 A L SHA E + LD+ ++ NW + +++ LN Y+ L +V Sbjct: 168 AGLL----SHALEDAEHFGWSLDRSKISHNWSTMVEGVQSHIGSLNWGYKVALRDNQVTY 223 Query: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFFRL 193 + R V++ ++ + N I++ATG + +PE IPG E G SD F L Sbjct: 224 LNAKGRLISPHEVQITDKNQKVSTITGNKIILATGERPKYPE-IPGAVEYGITSDDLFSL 282 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 P K +V+GA Y+ +E AG LG + +++R +LR FD+ + + D+ G+ Sbjct: 283 PYFPGKTLVIGASYVALECAGFLASLGGDVTVMVR-SILLRGFDQQMAEKVGDYMENHGV 341 Query: 254 NVHKLS--------KIVKVEKNVETDKL-KIHMNDSKSI-DDVDELIWTIGRKSHLG-MG 302 KL K+V E N L K H D K ++ + +I+ +GR+ L + Sbjct: 342 KFAKLCVPDEIKQLKVVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKVL 401 Query: 303 SENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV-VGKVELTPVAIAAGRKLSNRLFGPEK 361 E VG+KL+ + +++ + + T V N+Y++GD+ GK +LTPVAI AGR L+ RLF Sbjct: 402 CETVGVKLDKNGRVVCTDDEQTTVSNVYAIGDINAGKPQLTPVAIQAGRYLARRLFAGA- 460 Query: 362 FRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP 421 + DY NV + +F+ E G+ G+SE++AIEKYG ++I+VY+S F + + + + Sbjct: 461 --TELTDYSNVATTVFTPLEYGACGLSEEDAIEKYGDKDIEVYHSNFKPLEWTVAHREDN 518 Query: 422 TRY-KIVC-AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 Y K+VC N +V+GLH++G ++ EI QG+ VAIKMGATKADFD + IHPT +E Sbjct: 519 VCYMKLVCRKSDNMRVLGLHVLGPNAGEITQGYAVAIKMGATKADFDRTIGIHPTCSETF 578 Query: 480 VTM 482 T+ Sbjct: 579 TTL 581 >4LA1-A nrPDB Length = 602 Score = 261 bits (667), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 162/468 (34%), Positives = 258/468 (55%), Gaps = 35/468 (7%) Query: 40 RRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL 90 + AA YGAK +++ LGGTCVNVGC+PKK+M A L+ + A +G Sbjct: 130 KEAAKYGAKIAVLDYVEPTPMGTTWGLGGTCVNVGCIPKKLMHQAGLLSHSLEDAQHFGW 189 Query: 91 YQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQ 150 LDK ++ +W + +++ LN Y+ +L V + V++ Sbjct: 190 ----SLDKSEISHDWSTMVEGVQSHIGSLNWGYKVSLRDNAVTYLNARGMLLSPHEVQIT 245 Query: 151 KRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFFRLEEQPKKVVVVGAGYIG 209 +++ + N I++ATG + +PE IPG E G SD F L P K +VVGA Y+ Sbjct: 246 EKNKKVSTITGNKIILATGERPKYPE-IPGAIEYGITSDDLFSLPYFPGKTLVVGASYVA 304 Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS---KIVKVEK 266 ++ AG LG + +++R +LR FD+ + + D+ G+ KL +I ++ K Sbjct: 305 LKCAGFLASLGGDVTVMVR-SILLRGFDQQMAEKVGDYMENHGVKFAKLCVPDEITQL-K 362 Query: 267 NVETDK-------LKIHMNDSKSI-DDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQII 317 V+T+ +K H D K ++ + +I+ +GR+ L + E VG+KL+ + +++ Sbjct: 363 PVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKLNCEAVGVKLDKNGRVV 422 Query: 318 ADEYQNTNVPNIYSLGDV-VGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 + + T V NIY++GD+ GK +LTPVAI AGR L+ RLF + DY NV + + Sbjct: 423 CSDDEQTTVSNIYAIGDINAGKPQLTPVAIHAGRYLARRLFAGA---TELTDYSNVATTV 479 Query: 377 FSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY-KIVC-AGPNEK 434 F+ E G+ G+SE++AIEKYG +I+VY+S F + + + + Y K+VC N + Sbjct: 480 FTPLEYGACGLSEEDAIEKYGDNDIEVYHSHFKPLEWTVAHREDNVCYMKLVCRISDNMR 539 Query: 435 VVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 V+GLH++G ++ EI QG+ VAIKMGATK DFD + IHPT +E T+ Sbjct: 540 VLGLHVLGPNAGEITQGYAVAIKMGATKEDFDRTIGIHPTCSETFTTL 587 >4B1B-A nrPDB Length = 542 Score = 256 bits (653), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 168/502 (33%), Positives = 268/502 (53%), Gaps = 59/502 (11%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKK 70 +T YDY+VIGGG GG+ASA+ AA++GA+ LL + +GGTCVNVGCVPKK Sbjct: 39 HTYDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKK 98 Query: 71 VMWYASDLATRVS-HANEYGL-YQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLE 128 +M YA + + + YG + NL D W + +++ LN Y L Sbjct: 99 LMHYAGHMGSIFKLDSKAYGWKFDNLKHD-------WKKLVTTVQSHIRSLNFSYMTGLR 151 Query: 129 KEKVDVVFGWARFNKDGNVEVQKRDNTT--EVYSANHILVATGGKAIFPENIPGF-ELGT 185 KV + G A+ V + + + E + +IL+ATG + P+++ G EL Sbjct: 152 SSKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSI 211 Query: 186 DSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTIT 245 SD F L++ P K +VVGA Y+ +E +G + LG + + +R VLR FD+ + Sbjct: 212 TSDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVR-SIVLRGFDQQCAVKVK 270 Query: 246 DHY------VKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 + K GI KL+K+ DK+ + +D K+ + D +++ IGRK + Sbjct: 271 LYMEEQGVMFKNGILPKKLTKM--------DDKILVEFSD-KTSELYDTVLYAIGRKGDI 321 Query: 300 -GMGSENVGIKLN-SHDQIIADEYQNTNVPNIYSLGDVVGKV-ELTPVAIAAGRKLSNRL 356 G+ E++ + +N S+++IIAD TN+P+I+++GDV V EL PVAI AG L+ RL Sbjct: 322 DGLNLESLNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRL 381 Query: 357 FGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAML 416 F K ++ +DY +P+ I++ E G+ G SE++A E YGK N++V+ +F + + + Sbjct: 382 F---KDSDEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAV 438 Query: 417 SEKSPTRY---------------KIVC-AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGA 460 + R K+VC + +V+G H VG ++ E+ QG +A+++ Sbjct: 439 HRQKHIRAQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKV 498 Query: 461 TKADFDNCVAIHPTSAEELVTM 482 K DFDNC+ IHPT AE + + Sbjct: 499 KKKDFDNCIGIHPTDAESFMNL 520 >2WOV-A nrPDB Length = 495 Score = 254 bits (648), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 169/489 (34%), Positives = 256/489 (52%), Gaps = 44/489 (8%) Query: 21 TKHYDYLVIGGGSGGVASARRAAS-YGAKTLLVEAK---------ALGGTCVNVGCVPKK 70 +K +D +VIG GSGG+ + AA+ YG + +V+ + ALGGTCVNVGCVPKK Sbjct: 5 SKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCVPKK 64 Query: 71 VMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL-EK 129 +M + + + +G D + NW + ++ V +N Y+ + Sbjct: 65 LMVTGAQYMDHLRESAGFGWE----FDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDT 120 Query: 130 EKVDVVFGWARFNKDGNVEVQK----RDNTTEVYSANHILVATGGKAIFPENIPGFELGT 185 E +D GW V V++ + E A+HIL+ATG P IPG E Sbjct: 121 EGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPA-IPGIEHCI 179 Query: 186 DSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL---GSETHLVIRGETVLRKFDECIQN 242 S+ F L E P++V+ VG G+I +E AG+F+ G + L R +LR FDE I+ Sbjct: 180 SSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIRE 239 Query: 243 TITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR---KSHL 299 +T GI + KV N + K + K++D VD ++ IGR + L Sbjct: 240 EVTKQLTANGIEIMTNENPAKVSLNTDGSK-HVTFESGKTLD-VDVVMMAIGRIPRTNDL 297 Query: 300 GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGP 359 +G NVG+KL + DE+ TNVPNIY++GD+ ++ LTPVAI G L + +FG Sbjct: 298 QLG--NVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFG- 354 Query: 360 EKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEK 419 K R K D+ V S +FS P G+ G+ E+ A +++ E + VY S FT + + + Sbjct: 355 NKPR--KTDHTRVASAVFSIPPIGTCGLIEEVAAKEF--EKVAVYMSSFTPLMHNI---- 406 Query: 420 SPTRYK-----IVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPT 474 S ++YK IV + V+G+H++GD + EI+Q GV +++ A +DF N + +HPT Sbjct: 407 SGSKYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPT 466 Query: 475 SAEELVTMR 483 SAEEL +MR Sbjct: 467 SAEELCSMR 475 >4DNA-A nrPDB Length = 463 Score = 252 bits (643), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 158/462 (34%), Positives = 248/462 (53%), Gaps = 21/462 (4%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 YD VIGGGSGGV S R AA+ G K + E GGTCV GCVPKK+ YAS A Sbjct: 6 YDLFVIGGGSGGVRSGRLAAALGKKVAIAEEFRYGGTCVIRGCVPKKLYVYASQFAEHFE 65 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 A +G F+W + ++ + RL G+Y+K L +++ A Sbjct: 66 DAAGFGWTVG------ESRFDWAKLVAAKEQEIARLEGLYRKGLANAGAEILDTRAELAG 119 Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVV 203 V++ T +A I++A GG + +PG EL S+ F L P+ +++ Sbjct: 120 PNTVKLLASGKTV---TAERIVIAVGGHPSPHDALPGHELCITSNEAFDLPALPESILIA 176 Query: 204 GAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVK 263 G GYI +E A +FHGLG +T L+ RG+ +L +FD+ ++ + ++GI + I Sbjct: 177 GGGYIAVEFANIFHGLGVKTTLIYRGKEILSRFDQDMRRGLHAAMEEKGIRILCEDIIQS 236 Query: 264 VEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEYQ 322 V + + ++ M + + D+++ +GR + G+G E G++ N II D + Sbjct: 237 VSADADGRRVATTMKHGEIV--ADQVMLALGRMPNTNGLGLEAAGVRTNELGAIIVDAFS 294 Query: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKL--DYENVPSVIFSHP 380 T+ P IY+LGDV +V+LTPVAI F +++N+ D++ + + +FS P Sbjct: 295 RTSTPGIYALGDVTDRVQLTPVAIH-----EAMCFIETEYKNNPTSPDHDLIATAVFSQP 349 Query: 381 EAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHI 440 E G++GI+E+EA K+ + I+VY ++F M + K T K+V + KVVG HI Sbjct: 350 EIGTVGITEEEAARKF--QEIEVYRAEFRPMKATLSGRKEKTIMKLVVNAADRKVVGAHI 407 Query: 441 VGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 +G + E+ Q G++++ G TK DFD +A+HPT+AEELVTM Sbjct: 408 LGHDAGEMAQLLGISLRAGCTKDDFDRTMAVHPTAAEELVTM 449 >2NVK-X nrPDB Length = 488 Score = 251 bits (642), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 163/479 (34%), Positives = 261/479 (54%), Gaps = 34/479 (7%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE----------AKALGGTCVNVGCVPKKVMW 73 YD +VIGGGS G+A A+ A GA+ ++ +GGTCVNVGC+PKK+M Sbjct: 10 YDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMH 69 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 AS L V A YG + + + +W + Q ++ +N + + +L +KV+ Sbjct: 70 QASLLGEAVHEAAAYGWNVD-----DKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVE 124 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFFR 192 + G F D + + K + +A ++A GG+ +P +IPG E G SD F Sbjct: 125 YINGLGSF-VDSHTLLAKLKSGERTITAQTFVIAVGGRPRYP-DIPGAVEYGITSDDLFS 182 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 L+ +P K +VVGAGYIG+E AG GLG E +++R VLR FD+ + + + G Sbjct: 183 LDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVR-SIVLRGFDQQMAELVAASMEERG 241 Query: 253 INVHKLSKIVKVEKNVETDKLKIHMN---DSKSIDDVDELIWTIGRKSHL-GMGSENVGI 308 I + + + VEK + L + N +S D D ++W IGRK + + N G+ Sbjct: 242 IPFLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDVYDTVLWAIGRKGLVDDLNLPNAGV 301 Query: 309 KLNSHDQIIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRNDKL 367 + D+I D + TNV NIY++GD++ GK ELTPVA+ AGR L+ RL+G ++ Sbjct: 302 TVQK-DKIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGS---TQRM 357 Query: 368 DYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIV 427 DY++V + +F+ E +G+SE++A++++G + I+V++ + + + +KS RY + Sbjct: 358 DYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEF-FIPQKS-VRYCYL 415 Query: 428 CAGP----NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 A +++V GLH +G + E++QGF A+K G T N V IHPT+AEE + Sbjct: 416 KAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRL 474 >2YAU-A nrPDB Length = 511 Score = 246 bits (629), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 159/485 (32%), Positives = 251/485 (51%), Gaps = 36/485 (7%) Query: 21 TKHYDYLVIGGGSGGVASARRAA-SYGAKTLLVEAKA---------LGGTCVNVGCVPKK 70 ++ YD +V+G GSGG+ + AA ++ K +V+ +A LGGTCVNVGCVPKK Sbjct: 22 SRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCVPKK 81 Query: 71 VMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL-EK 129 +M + + + +G +D+E L NW ++ V+ +N Y+ + Sbjct: 82 LMVTGAQYMDLIRESGGFGW----EMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADT 137 Query: 130 EKVDVVFGWARFNKDGNVEVQKRDN----TTEVYSANHILVATGGKAIFPEN--IPGFEL 183 E + G+ V V+K ++ E +IL+ATG +P +PG E Sbjct: 138 EGLSFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGS---WPTRLGVPGDEF 194 Query: 184 GTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHG---LGSETHLVIRGETVLRKFDECI 240 S+ F LE+ PK+++ VG GYI +E AG+F+G G L RG+ +LR FD + Sbjct: 195 CITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEV 254 Query: 241 QNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR-KSHL 299 + ++T GI V K+ KN E +H ND +D D+++ IGR Sbjct: 255 RKSLTKQLGANGIRVRTNLNPTKITKN-EDGSNHVHFNDGTE-EDYDQVMLAIGRVPRSQ 312 Query: 300 GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGP 359 + + G++ + + D Y T+V NIY++GDV +V LTPVAI G +FG Sbjct: 313 ALQLDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFGG 372 Query: 360 EKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEK 419 + D+ V +FS P G+ G++E+EA + Y E + VY S FT + + + K Sbjct: 373 ---KPRATDHTKVACAVFSIPPIGTCGMTEEEAAKNY--ETVAVYASSFTPLMHNISGSK 427 Query: 420 SPT-RYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEE 478 +I+ N +V+G+H++GDS+ EI+Q G+ +KMGA +DF + + +HPTSAEE Sbjct: 428 HKEFMIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAEE 487 Query: 479 LVTMR 483 L +MR Sbjct: 488 LCSMR 492 >2CFY-A nrPDB Length = 521 Score = 244 bits (624), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 160/465 (34%), Positives = 254/465 (54%), Gaps = 33/465 (7%) Query: 40 RRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL 90 + AA YG K ++++ LGGTCVNVGC+PKK+M A+ L + + YG Sbjct: 51 KEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGW 110 Query: 91 YQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQ 150 +E + +W + ++ LN Y+ L ++KV + +F ++ Sbjct: 111 KV-----EETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKAT 165 Query: 151 KRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFFRLEEQPKKVVVVGAGYIG 209 ++YSA L+ATG + + IPG E SD F L P K +VVGA Y+ Sbjct: 166 NNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVA 224 Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVE 269 +E AG G+G + +++R +LR FD+ + N I +H + GI + +KVE+ +E Sbjct: 225 LECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQ-IE 282 Query: 270 TD---KLKIHMNDSKSID----DVDELIWTIGRKSHL-GMGSENVGIKLNSHD-QIIADE 320 +L++ + S + + + ++ IGR + +G E VG+K+N +I + Sbjct: 283 AGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTD 342 Query: 321 YQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSH 379 + TNVP IY++GD++ KVELTPVAI AGR L+ RL+ K DYENVP+ +F+ Sbjct: 343 EEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTV---KCDYENVPTTVFTP 399 Query: 380 PEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY-KIVC-AGPNEKVVG 437 E G+ G+SE++A+EK+G+ENI+VY+S F + + + S + Y KI+C NE+VVG Sbjct: 400 LEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVG 459 Query: 438 LHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 H++G ++ E+ QGF A+K G TK D+ + IHP AE T+ Sbjct: 460 FHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTL 504 >4KPR-E nrPDB Length = 499 Score = 244 bits (624), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 156/440 (35%), Positives = 246/440 (55%), Gaps = 24/440 (5%) Query: 56 ALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAY 115 LGGTCVNVGC+PKK+M A+ L + + YG ++ + +W + + + Sbjct: 54 GLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKL-----EDTVKHDWEKMTESVQNH 108 Query: 116 VHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFP 175 + LN Y+ L ++KV + +F + +VYSA L+ATG + + Sbjct: 109 IGSLNWGYRVALREKKVVYENAYGKFIGPHKIMATNNKGKEKVYSAERFLIATGERPRY- 167 Query: 176 ENIPG-FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLR 234 IPG E SD F L P K +VVGA Y+ +E AG G+G + +++R +LR Sbjct: 168 LGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVR-SILLR 226 Query: 235 KFDECIQNTITDHYVKEGINVHKL---SKIVKVEKNVETDKLKI---HMNDSKSIDD-VD 287 FD+ + N I +H + GI + +KI ++E +LK+ N ++I+D + Sbjct: 227 GFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGT-PGRLKVTAKSTNSEETIEDEFN 285 Query: 288 ELIWTIGRKSHL-GMGSENVGIKLNSHD-QIIADEYQNTNVPNIYSLGDVV-GKVELTPV 344 ++ +GR S +G E VG+K+N +I + + TNVP IY++GD++ GK+ELTPV Sbjct: 286 TVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPV 345 Query: 345 AIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVY 404 AI AGR L+ RL+G K DY+NVP+ +F+ E G G+SE++A+EK+G+ENI+VY Sbjct: 346 AIQAGRLLAQRLYGGSTV---KCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVY 402 Query: 405 NSKFTAMYYAMLSEKSPTRY-KIVC-AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATK 462 +S F + + + S + Y K++C NE+VVG H++G ++ E+ QGF A+K G TK Sbjct: 403 HSFFWPLEWTVPSRDNNKCYAKVICNLKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTK 462 Query: 463 ADFDNCVAIHPTSAEELVTM 482 D+ + IHP AE T+ Sbjct: 463 QQLDSTIGIHPVCAEIFTTL 482 >4NEW-A nrPDB Length = 492 Score = 243 bits (620), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 161/482 (33%), Positives = 245/482 (50%), Gaps = 33/482 (6%) Query: 22 KHYDYLVIGGGSGGVASARRAAS-YGAKTLLVEAK---------ALGGTCVNVGCVPKKV 71 K +D +VIG GSGG+ +A AA+ Y + +++ + ALGGTCVNVGCVPKK+ Sbjct: 4 KIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVPKKL 63 Query: 72 MWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL-EKE 130 M + + + +G D+ L W +D V +N Y + + E Sbjct: 64 MVTGAQYMEHLRESAGFGW----EFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTE 119 Query: 131 KVDVVFGWARFNKDGNVEVQKRDNTT----EVYSANHILVATGGKAIFPENIPGFELGTD 186 ++ GW V V++ + E HIL+A+G P NIPG E Sbjct: 120 GLEFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMP-NIPGIEHCIS 178 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL---GSETHLVIRGETVLRKFDECIQNT 243 S+ F L E P++V+ VG G+I +E AG+F+ + L RGE +LR FD ++ Sbjct: 179 SNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLREE 238 Query: 244 ITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMG 302 +T GI + KVE N + K + K +D D ++ IGR + Sbjct: 239 LTKQLTANGIQILTKENPAKVELNADGSK-SVTFESGKKMD-FDLVMMAIGRSPRTKDLQ 296 Query: 303 SENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKF 362 +N G+ + + + DEY TNV NIY++GDV +V LTPVAI L + +FG Sbjct: 297 LQNAGVMIK-NGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGTTP- 354 Query: 363 RNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPT 422 K D+ V S +FS P G+ G+ E+ A ++Y E + VY S FT + + + K T Sbjct: 355 --RKTDHTRVASAVFSIPPIGTCGLIEEVASKRY--EVVAVYLSSFTPLMHKVSGSKYKT 410 Query: 423 RY-KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVT 481 KI+ + V+G+H++GD++ EI+QG G+ +K+ A +DF N + +HPTSAEEL + Sbjct: 411 FVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEELCS 470 Query: 482 MR 483 MR Sbjct: 471 MR 472 >5W1J-A nrPDB Length = 584 Score = 243 bits (619), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 159/484 (32%), Positives = 258/484 (53%), Gaps = 36/484 (7%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWY 74 YD ++IGGGSGG+A A+ +A GAK L++ LGGTCVNVGC+PKK+M Sbjct: 104 YDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNVGCIPKKLMHQ 163 Query: 75 ASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134 A+ L + A +G D + +W + + ++H LN Y+ ++ V Sbjct: 164 AALLNHYMEDAKSFGW------DVDKGPHDWVKMVEGIQDHIHALNFGYRSSMMNANVKY 217 Query: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGF-ELGTDSDGFFRL 193 + ++ + + + N I+VATG + +P IPG E G SD F L Sbjct: 218 LNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPP-IPGAKEYGITSDDLFTL 276 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 + P K + VGA Y+ +E AG +G + +++R LR FD+ + I+D+ K G+ Sbjct: 277 DHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVR-SIFLRGFDQQMAGLISDYIAKYGV 335 Query: 254 NVHKLSKIVKV----EKNVETDKLKI------HMNDSKSIDDVDELIWTIGR-KSHLGMG 302 + V E + E+ KL I H + + D + +++ +GR +G Sbjct: 336 KFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIG 395 Query: 303 SENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGK-VELTPVAIAAGRKLSNRLFGPEK 361 +NV +K ++ +++ D+ + TNVPNIY++GDV +LTP+AI AG+ L+ RL+ + Sbjct: 396 LQNVDVK-TTNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLARRLYTADD 454 Query: 362 FRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP 421 R D Y NVP+ +F+ E G IG+SE+ AI K+G++NI+V++S F + + + Sbjct: 455 CRTD---YTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPLEWTVPHRPDN 511 Query: 422 TRYK--IVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 T Y I+ + +VVG H+ G ++ E+ QG+ VA+ +GA K DFD + IHPT +E Sbjct: 512 TCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTIGIHPTCSETF 571 Query: 480 VTMR 483 T+R Sbjct: 572 TTLR 575 >1FEC-A nrPDB Length = 490 Score = 234 bits (596), Expect = 9e-62, Method: Compositional matrix adjust. Identities = 162/489 (33%), Positives = 250/489 (51%), Gaps = 44/489 (8%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLV----------EAKALGGTCVNVGCVPKK 70 ++ YD +VIG GSGG+ + AAS K + V ALGGTCVNVGCVPKK Sbjct: 1 SRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPKK 60 Query: 71 VMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL-EK 129 +M ++ + + +G LD+E + NW ++ V +N Y+ + Sbjct: 61 LMVTGANYMDTIRESAGFGW----ELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADT 116 Query: 130 EKVDVVFGWARFNKDGNVEVQKRDNTT----EVYSANHILVATGGKAIFPEN--IPGFEL 183 E + G+ + V V++ + E +IL+ATG +P++ I G +L Sbjct: 117 EGLTFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGS---WPQHLGIEGDDL 173 Query: 184 GTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL---GSETHLVIRGETVLRKFDECI 240 S+ F L+E PK+ + VG GYI IE AG+F+ G + L RG+ +LR FD + Sbjct: 174 CITSNEAFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSEL 233 Query: 241 QNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR-KSHL 299 + +T+ GINV KV KN + + + + +++ D D ++ IGR Sbjct: 234 RKQLTEQLRANGINVRTHENPAKVTKNADGTRHVVFESGAEA--DYDVVMLAIGRVPRSQ 291 Query: 300 GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGP 359 + E G+++ + I D Y TNV NIY++GDV +V LTPVAI G + +F Sbjct: 292 TLQLEKAGVEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFAN 351 Query: 360 EKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEK 419 + D+ V +FS P G G E++A +KY + + VY S FT + + + Sbjct: 352 ---KPRATDHTKVACAVFSIPPMGVCGYVEEDAAKKY--DQVAVYESSFTPLMHNI---- 402 Query: 420 SPTRYK-----IVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPT 474 S + YK IV + +V+G+H++GDSS EI+Q + +KMGA +DF N + +HPT Sbjct: 403 SGSTYKKFMVRIVTNHADGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPT 462 Query: 475 SAEELVTMR 483 SAEEL +MR Sbjct: 463 SAEELCSMR 471 >5X1Y-B nrPDB Length = 554 Score = 206 bits (523), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 136/464 (29%), Positives = 243/464 (52%), Gaps = 21/464 (4%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 N +YD L+IG G+ +SA +A YGAK ++E +GGTCVN+GCVP K + A ++ Sbjct: 81 NEDNYDLLIIGSGAAAFSSAIKAIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEI- 139 Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRL-NGIYQKNLEKEKVDVVFGW 138 +S N + + L + ++D V L N Y +++ D++ G Sbjct: 140 IHLSKDNPF-----IGLQTSAGEVDLASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGE 194 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG--TDSDGFFRLEEQ 196 A+F VEV SA L+ATG P+ I G E S L++ Sbjct: 195 AKFVDASTVEVNGAK-----LSAKRFLIATGASPSLPQ-ISGLEKMDYLTSTTLLELKKI 248 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 PK++ V+G+GYIG+EL +FH LGSE L+ R E +L+++D I ++ +++GIN+ Sbjct: 249 PKRLTVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLV 308 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQ 315 K + +VE++ E ++ + +N S+ + + D+L+ GRK + + G++ +++ Sbjct: 309 KGATFERVEQSGEIKRVYVTVNGSREVIESDQLLVATGRKPNTDSLNLSAAGVETGKNNE 368 Query: 316 IIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSV 375 I+ +++ T+ IY+ GDV + VA G +++ G N K+D VP+V Sbjct: 369 ILINDFGQTSNEKIYAAGDVTLGPQFVYVAAYEGGIITDNAIGG---LNKKIDLSVVPAV 425 Query: 376 IFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKV 435 F++P ++G++E++A EK ++K A+ A+++ ++ +K+V KV Sbjct: 426 TFTNPTVATVGLTEEQAKEK--GYDVKTSVLPLDAVPRAIVNRETTGVFKLVADAETLKV 483 Query: 436 VGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +G+HIV +++ +++ +A+K G T D +A + T AE L Sbjct: 484 LGVHIVSENAGDVIYAASLAVKFGLTVEDLTETLAPYLTMAEGL 527 >1EBD-A nrPDB Length = 455 Score = 193 bits (491), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 135/459 (29%), Positives = 228/459 (49%), Gaps = 24/459 (5%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSH 84 + LV+G G GG +A RAA G K +VE LGG C+NVGC+P K + AS + H Sbjct: 5 ETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALISASHRYEQAKH 64 Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKD 144 + E G + E++T ++ + ++ + + V +L G + L+ KV++V G A F Sbjct: 65 SEEMG------IKAENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFVDA 118 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGT---DSDGFFRLEEQPKKVV 201 V V D + + Y+ + ++ATG + P +P F+ DS G L E PK +V Sbjct: 119 NTVRVVNGD-SAQTYTFKNAIIATGSR---PIELPNFKFSNRILDSTGALNLGEVPKSLV 174 Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKI 261 V+G GYIGIEL + G++ ++ +L F++ + I K+G+ V + Sbjct: 175 VIGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNALA 234 Query: 262 VKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQIIADE 320 E+ + + N D D ++ T+GR+ + +G E +GIK+ + I D+ Sbjct: 235 KGAEEREDGVTVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQ 294 Query: 321 YQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHP 380 T+VPNI+++GD+V L A G+ + + G +DY +P+V+FS P Sbjct: 295 QCRTSVPNIFAIGDIVPGPALAHKASYEGKVAAEAIAG----HPSAVDYVAIPAVVFSDP 350 Query: 381 EAGSIGISEKEAIEKYGKENIKVYNSK--FTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 E S+G E++A + E I V +K F A A+ + K+V + ++G Sbjct: 351 ECASVGYFEQQAKD----EGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGA 406 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 I+G ++++++ G+AI+ G T D + HPT E Sbjct: 407 QIIGPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGE 445 >5U8W-A nrPDB Length = 481 Score = 184 bits (466), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 134/476 (28%), Positives = 235/476 (49%), Gaps = 30/476 (6%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-------KALGGTCVNVGCVPKK 70 S ++ +D +VIG G GG +A RAA G KT +E ALGGTC+NVGC+P K Sbjct: 2 SHMSQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSK 61 Query: 71 VMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKE 130 + D + + A E ++ ++ + +T + P ++ V L G + Sbjct: 62 ALL---DSSYKYHEAKEA--FKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKAN 116 Query: 131 KVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG----TD 186 V G + + VEV D T+V A ++++A+G + P IP L D Sbjct: 117 GVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSR---PVEIPPAPLTDDIIVD 173 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD 246 S G + PKK+ V+GAG IG+EL V+ LG+E ++ + L DE I Sbjct: 174 STGALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALK 233 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDS--KSIDDVDELIWTIGRKS-HLGMGS 303 K+G+N+ +++ E V+ ++ + D+ + + D+LI +GR+ + + Sbjct: 234 VLTKQGLNIRLGARVTASE--VKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLA 291 Query: 304 ENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFR 363 + G+ L+ I D++ T+VP ++++GDVV L A G ++ R+ G Sbjct: 292 ADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAG----H 347 Query: 364 NDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTR 423 +++Y+ +PSVI++HPE +G +E + ++ G E + V F A AM + + Sbjct: 348 KAQMNYDLIPSVIYTHPEIAWVGKTE-QTLKAEGVE-VNVGTFPFAASGRAMAANDTTGL 405 Query: 424 YKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 K++ ++V+G+H++G S+AE++Q + ++ G + D V HPT +E L Sbjct: 406 VKVIADAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEAL 461 >2EQ6-A nrPDB Length = 464 Score = 182 bits (461), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 147/471 (31%), Positives = 229/471 (48%), Gaps = 33/471 (7%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 T K YD +VIG G GG +A RAA G K L VEA +GG C+NVGC+P K + +A++ Sbjct: 2 TPMKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAET 61 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + A +GL LD + L W RD V +L G L+ V+++ G+ Sbjct: 62 LHHLKVAEGFGLKAKPELDLKKLG-GW------RDQVVKKLTGGVGTLLKGNGVELLRGF 114 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGT---DSDGFFRLEE 195 AR VEV E Y A +++ATG + P + GF G DS ++EE Sbjct: 115 ARLVGPKEVEV-----GGERYGAKSLILATGSE---PLELKGFPFGEDVWDSTRALKVEE 166 Query: 196 Q-PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 PK+++V+G G +G+EL V+ LG+E L+ +L + D + KEGI Sbjct: 167 GLPKRLLVIGGGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIR 226 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDS----KSIDDVDELIWTIGRKSHL-GMGSENVGIK 309 V +K V EK D L + + + VD+++ +GRK G+G E G+K Sbjct: 227 VRTKTKAVGYEKK--KDGLHVRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGLGLEKAGVK 284 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 ++ I + T+VP +Y++GD L A+ G + G ++ DY Sbjct: 285 VDERGFIRVNARMETSVPGVYAIGDAARPPLLAHKAMREGLIAAENAAG----KDSAFDY 340 Query: 370 ENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 + VPSV+++ PE +G++E+EA K +KV A A+ + K+V Sbjct: 341 Q-VPSVVYTSPEWAGVGLTEEEA--KRAGYKVKVGKFPLAASGRALTLGGAEGMVKVVGD 397 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELV 480 + ++G+ IVG + E++ +A++MGAT D V HPT +E L+ Sbjct: 398 EETDLLLGVFIVGPQAGELIAEAALALEMGATLTDLALTVHPHPTLSESLM 448 >5TR3-A nrPDB Length = 481 Score = 182 bits (461), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 131/471 (27%), Positives = 230/471 (48%), Gaps = 26/471 (5%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-------KALGGTCVNVGCVPKKVMW 73 T+ +D +VIG G GG +A +AA G KT +E ALGGTC+NVGC+P K + Sbjct: 5 TQKFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALL 64 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 D + + A E + + + + ++ V L G + V Sbjct: 65 ---DSSWKYKEAKES--FNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVT 119 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG----TDSDG 189 + G + VEV K D TTEV A ++++A+G + P +IP + DS G Sbjct: 120 SIQGHGKLLAGKKVEVTKADGTTEVIEAENVILASGSR---PIDIPPAPVDQNVIVDSTG 176 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 + PK++ V+GAG IG+EL V+ LG+E ++ +T L D + Sbjct: 177 ALEFQAVPKRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLT 236 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS-HLGMGSENVGI 308 K+G+++ +++ + N ++ + + D+LI +GR+ + + + G+ Sbjct: 237 KQGLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGV 296 Query: 309 KLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLD 368 ++ I D+Y T+VP +Y++GDVV + L A G + R+ G +++ Sbjct: 297 TIDERGYIFVDDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKG----HKAQMN 352 Query: 369 YENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVC 428 Y+ +PSVI++HPE +G +E +A++ G E + V F A AM + + K++ Sbjct: 353 YDLIPSVIYTHPEIAWVGKTE-QALKAEGVE-VNVGTFPFAASGRAMAANDTGGFVKVIA 410 Query: 429 AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G+H++G S+AE++Q +A++ G + D V HPT +E L Sbjct: 411 DAKTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEAL 461 >3LAD-A nrPDB Length = 476 Score = 180 bits (456), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 124/468 (26%), Positives = 228/468 (48%), Gaps = 20/468 (4%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-------KALGGTCVNVGCVPKKVMW 73 ++ +D +VIG G GG +A ++A G KT L+E ALGGTC+NVGC+P K + Sbjct: 1 SQKFDVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKTALGGTCLNVGCIPSKALL 60 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 D + + A+E ++ + + + P ++D V L G ++ V Sbjct: 61 ---DSSYKFHEAHES--FKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANGVT 115 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-FPENIPGFELGTDSDGFFR 192 + G + VEV D +++V ++++A+G K + P ++ DS G Sbjct: 116 LFEGHGKLLAGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQDVIVDSTGALD 175 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 + P K+ V+GAG IG+EL V+ LG+E ++ + L DE + K+G Sbjct: 176 FQNVPGKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQG 235 Query: 253 INVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS-HLGMGSENVGIKLN 311 + + +++ E + +K + + D+LI +GR+ + + + G+ L+ Sbjct: 236 LKILLGARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLD 295 Query: 312 SHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYEN 371 I D+Y T+VP +Y++GDVV L A G ++ R+ G +++Y+ Sbjct: 296 ERGFIYVDDYCATSVPGVYAIGDVVRGAMLAHKASEEGVVVAERIAG----HKAQMNYDL 351 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 +P+VI++HPE +G +E+ + N+ V+ F A AM + + K++ Sbjct: 352 IPAVIYTHPEIAGVGKTEQALKAEGVAINVGVF--PFAASGRAMAANDTAGFVKVIADAK 409 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G+H++G S+AE++Q +A++ G + D V HP +E L Sbjct: 410 TDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEAL 457 >6BZ0-A nrPDB Length = 480 Score = 171 bits (434), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 124/469 (26%), Positives = 231/469 (49%), Gaps = 27/469 (5%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK------ALGGTCVNVGCVPKKVMWY 74 ++ +D +VIGGG GG +A RAA G K +E + +LGGTC+NVGC+P K + Sbjct: 5 SQQFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLD 64 Query: 75 ASD-LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 +S V H ++G+ + F+ + ++D V +L G + L+ ++ Sbjct: 65 SSHRYEDTVHHLADHGITTG------EVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIE 118 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP----GFELGTDSDG 189 + G + VE + T++ ++++A+G P NIP ++ DS G Sbjct: 119 WLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGS---VPVNIPVAPVDQDIIVDSTG 175 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 E PK++ V+GAG IG+EL V+ LG+E + + L D+ + Sbjct: 176 ALNFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILT 235 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGI 308 K+G+++ +K+ E N +K D+LI +GRK++ G+ +E+ GI Sbjct: 236 KQGLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGI 295 Query: 309 KLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLD 368 KL + +++ T+V +Y++GD+V L A+ G R+ G +++ Sbjct: 296 KLTERGLVEVNDHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHG----HAAQVN 351 Query: 369 YENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVC 428 Y+ + S+I++HPEA +G++E++A EK G E +K F A+ + + K V Sbjct: 352 YDTIISIIYTHPEAAWVGLTEEQAKEK-GHE-VKTGQFGFAVNGRALAAGEGAGFVKFVA 409 Query: 429 AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 ++++G+H++G ++++I+ +A++ ++ D HPT +E Sbjct: 410 DAKTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSE 458 >3URH-A nrPDB Length = 491 Score = 167 bits (424), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 131/470 (27%), Positives = 229/470 (48%), Gaps = 32/470 (6%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKAL-GGTCVNVGCVPKKVMWYASDLATRV 82 YD +VIG G GG A +AA G K +VE ++ GGTC+NVGC+P K + +AS++ Sbjct: 26 YDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEM---- 81 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHR-LNGI---YQKNLEKEKVDVVFGW 138 H ++GL + L ++ + N + +DA V ++G+ ++KN K+D G Sbjct: 82 FHQAQHGL-EALGVEVANPKLNLQKMMAHKDATVKSNVDGVSFLFKKN----KIDGFQGT 136 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTD------SDGFFR 192 + G V V +V A ++++ATG IPG E+ D S G Sbjct: 137 GKVLGQGKVSVTNEKGEEQVLEAKNVVIATGSDV---AGIPGVEVAFDEKTIVSSTGALA 193 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 LE+ P ++VVG G IG+EL V+ LG++ +V +T+L D + + K+G Sbjct: 194 LEKVPASMIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILGGMDGEVAKQLQRMLTKQG 253 Query: 253 INVHKLSKIVKVEKNVETDKLK---IHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIK 309 I+ +K+ K+ + K+ + ++ ++D LI T + S G+G G+ Sbjct: 254 IDFKLGAKVTGAVKSGDGAKVTFEPVKGGEATTLDAEVVLIATGRKPSTDGLGLAKAGVV 313 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 L+S ++ D + T++ +Y++GDVV L A G ++ + G + ++Y Sbjct: 314 LDSRGRVEIDRHFQTSIAGVYAIGDVVRGPMLAHKAEDEGVAVAEIIAG----QAGHVNY 369 Query: 370 ENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 + +P V+++ PE S+G +E+E K K+ FTA A ++ KI+ Sbjct: 370 DVIPGVVYTQPEVASVGKTEEEL--KAAGVAYKIGKFPFTANGRARAMLQTDGFVKILAD 427 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G HI+G + E++ V ++ G + D HPT +E + Sbjct: 428 KETDRVLGGHIIGFGAGEMIHEIAVLMEFGGSSEDLGRTCHAHPTMSEAV 477 >6CMZ-A nrPDB Length = 466 Score = 167 bits (423), Expect = 9e-42, Method: Compositional matrix adjust. Identities = 134/470 (28%), Positives = 216/470 (45%), Gaps = 28/470 (5%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 + +H LVIGGG GG +A RA G T+LVE LGGTC+N+GC+P K + + +D Sbjct: 3 AMKNEHTTLLVIGGGPGGYVAAIRAGQLGIPTVLVERDRLGGTCLNIGCIPSKALIHVAD 62 Query: 78 -LATRVSHANE--YGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134 HA E G+ P + W +D V RL L+K V V Sbjct: 63 AFEQACGHAGEGALGIRVRAPEIDIAKSVAW------KDGIVDRLTRGVGALLKKSGVRV 116 Query: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG---TDSDGFF 191 + G AR VEV + + H+L+ATG + P +P G S Sbjct: 117 LHGEARVIDGKTVEVVSAGHAVRI-GCEHLLLATGSE---PVELPSMPFGGHVVSSTDAL 172 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 PK++VVVGAGYIG+EL V+ LG + +V E VL +D + + D + Sbjct: 173 SPATLPKRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERVLPAYDAELVRPVADSLARL 232 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMND-SKSIDDVDELIWTIGRKSHL-GMGSENVGIK 309 G+ + K++ ++K+ +++ D ++ D ++ +GR+ + G G E + + Sbjct: 233 GVRLWLGHKVLGLDKH---GAVRVQAADGAEQTLPADRVLVAVGRRPRVDGFGLETLMLD 289 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 N I D+ T++ N++++GDV G+ L A+A G ++ + G R + Sbjct: 290 RNGRALRI-DDTCRTSMRNVWAIGDVAGEPMLAHRAMAQGEMVAELIAG----RRRQFMP 344 Query: 370 ENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 +P+V F+ PE + G S +A G + + + F A AM + + ++V Sbjct: 345 AAIPAVCFTDPEIVTAGWSPDDA-HAAGVDCLSA-SFPFAANGRAMTLQATDGFVRVVAR 402 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 N +VG VG +E+ F +++MGA D + HPT E L Sbjct: 403 RDNHLIVGWQAVGRGVSELAAAFSQSLEMGARLEDIGGTIHAHPTLGEAL 452 >1DXL-A nrPDB Length = 470 Score = 167 bits (422), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 128/470 (27%), Positives = 232/470 (49%), Gaps = 22/470 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYAS 76 ++ + D ++IGGG GG +A +AA G KT +E + ALGGTC+NVGC+P K + ++S Sbjct: 1 ASGSDENDVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSS 60 Query: 77 DLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 + H+ + N + ++ + ++D V L + +K KV V Sbjct: 61 HMYHEAKHS-----FANHGVKVSNVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVK 115 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG----TDSDGFFR 192 G+ +F + V + V HI++ATG +++PG + S G Sbjct: 116 GYGKFVSPSEISVDTIEGENTVVKGKHIIIATGSDV---KSLPGVTIDEKKIVSSTGALA 172 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 L E PKK+VV+GAGYIG+E+ V+ +GSE +V ++ D I+ K+G Sbjct: 173 LSEIPKKLVVIGAGYIGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQG 232 Query: 253 INVHKLSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIK 309 + +K+V V+ + + KL + ++I + D ++ + GR G+ + +G++ Sbjct: 233 MKFKLKTKVVGVDTSGDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVE 292 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 + +I+ +E +TNV +Y++GDV+ L A G L G + +DY Sbjct: 293 TDKLGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEYLAG----KVGHVDY 348 Query: 370 ENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 + VP V++++PE S+G +E E +++ G E +V F A A + + KI+ Sbjct: 349 DKVPGVVYTNPEVASVGKTE-EQVKETGVE-YRVGKFPFMANSRAKAIDNAEGLVKIIAE 406 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +K++G+HI+ ++ E++ +A++ A+ D HPT +E + Sbjct: 407 KETDKILGVHIMAPNAGELIHEAAIALQYDASSEDIARVCHAHPTMSEAI 456 >1V59-A nrPDB Length = 478 Score = 161 bits (408), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 131/476 (27%), Positives = 236/476 (49%), Gaps = 31/476 (6%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASD 77 T K +D ++IGGG G +A +AA G T VE + LGGTC+NVGC+P K + S Sbjct: 1 TINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSH 60 Query: 78 LATRV-SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 L ++ + A + G+ N + N F++ +D V +L G + +K KV Sbjct: 61 LFHQMHTEAQKRGIDVN-----GDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYK 115 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHIL------VATGGKAIFPENIPGFELGTD---- 186 G F + + V D +HIL VATG + + P PG E+ + Sbjct: 116 GNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSE-VTP--FPGIEIDEEKIVS 172 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD 246 S G L+E PK++ ++G G IG+E+ V+ LGS+ +V + D + Sbjct: 173 STGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQK 232 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSID----DVDELIWTIGRKSHL-GM 301 K+G++ +K++ ++N + + ++I + D+K+ + + L+ +GR+ ++ G+ Sbjct: 233 FLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGL 292 Query: 302 GSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEK 361 G+E +G++++ +++ D+ N+ P+I +GDV L A G L K Sbjct: 293 GAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEML----K 348 Query: 362 FRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP 421 + ++Y N+PSV++SHPE +G +E++ K + K+ F A A ++ + Sbjct: 349 TGHGHVNYNNIPSVMYSHPEVAWVGKTEEQL--KEAGIDYKIGKFPFAANSRAKTNQDTE 406 Query: 422 TRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 KI+ E+++G HI+G ++ E++ G+A++ GA+ D HPT +E Sbjct: 407 GFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSE 462 >2YQU-A nrPDB Length = 455 Score = 160 bits (404), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 131/463 (28%), Positives = 222/463 (47%), Gaps = 30/463 (6%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRV 82 YD LVIG G GG +A RAA G K +VE KALGGTC+ VGC+P K + ++ R+ Sbjct: 2 YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTE---RI 58 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 A + GL L + + + P +D V + +K + G ARF Sbjct: 59 YEAKK-GL---LGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFL 114 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP-GFELGTDSDGFFRLEEQPKKVV 201 + V V++ T E A +IL+ATG + P +E S E PK+++ Sbjct: 115 SERKVLVEE---TGEELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKRLI 171 Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKI 261 VVG G IG+EL V+H LG+E ++ + +L D + + K+G+ + ++ Sbjct: 172 VVGGGVIGLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKKQGLTIRTGVRV 231 Query: 262 VKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADE 320 V + ++++ + + + D ++ +GR+ + G+ EN G+ + +I DE Sbjct: 232 TAVVPEAKGARVEL---EGGEVLEADRVLVAVGRRPYTEGLSLENAGLSTDERGRIPVDE 288 Query: 321 YQNTNVPNIYSLGDVVGKVELTPVA----IAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 + T VP+IY++GDVV L A IAA + R FG +DY+ +PSV+ Sbjct: 289 HLRTRVPHIYAIGDVVRGPMLAHKASEEGIAAVEHMV-RGFG-------HVDYQAIPSVV 340 Query: 377 FSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVV 436 ++HPE ++G +E+E K KV ++A A ++ K++ ++++ Sbjct: 341 YTHPEIAAVGYTEEEL--KAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRIL 398 Query: 437 GLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 G+H +G ++L +A+ A+ D HP+ +E L Sbjct: 399 GVHGIGARVGDVLAEAALALFFKASAEDLGRAPHAHPSLSEIL 441 >4JDR-A nrPDB Length = 474 Score = 158 bits (400), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 129/474 (27%), Positives = 229/474 (48%), Gaps = 33/474 (6%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYA 75 MST K +V+G G G ++A R A G +T++VE LGG C+NVGC+P K + + Sbjct: 1 MSTEIK-TQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHV 59 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV 135 + + E+G+ P W ++ +++L G + KV VV Sbjct: 60 AKVIEEAKALAEHGIVFGEPKTDIDKIRTW------KEKVINQLTGGLAGMAKGRKVKVV 113 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI----FPENIPGFELGTDSDGFF 191 G +F +EV+ + T V + ++ ++A G + I P P TD+ Sbjct: 114 NGLGKFTGANTLEVEGENGKT-VINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDA---L 169 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 L+E P++++V+G G IG+E+ V+H LGS+ +V + V+ D+ I T K+ Sbjct: 170 ELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKK 229 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDD---VDELIWTIGR-KSHLGMGSENVG 307 N+ +K+ VE + D + + M K+ + D ++ IGR + + + G Sbjct: 230 -FNLMLETKVTAVE--AKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAG 286 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKL 367 ++++ I D+ TNVP+I+++GD+VG+ L + G + + G + + + K+ Sbjct: 287 VEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKV 346 Query: 368 DYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKF--TAMYYAMLSEKSPTRYK 425 +PS+ ++ PE +G++EKEA EK I + F A A+ S+ + K Sbjct: 347 ----IPSIAYTEPEVAWVGLTEKEAKEK----GISYETATFPWAASGRAIASDCADGMTK 398 Query: 426 IVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++ + +V+G IVG + E+L G+AI+MG D + HPT E + Sbjct: 399 LIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESV 452 >5J5Z-A nrPDB Length = 496 Score = 158 bits (399), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 132/464 (28%), Positives = 217/464 (46%), Gaps = 25/464 (5%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVS 83 D VIG G GG +A +AA G KT+ +E + LGGTC+NVGC+P K + S ++ Sbjct: 30 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHY-YHMA 88 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 H ++ + ++ + N + +++ V L G ++ KV V G+ + Sbjct: 89 HGKDFA---SRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITG 145 Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTD----SDGFFRLEEQPKK 199 V K D T+V +IL+ATG + + P PG + D S G L++ P+K Sbjct: 146 KNQVTATKADGGTQVIDTKNILIATGSE-VTP--FPGITIDEDTIVSSTGALSLKKVPEK 202 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLV-----IRGETVLRKFDECIQNTITDHYVKEGIN 254 +VV+GAG IG+EL V+ LG++ V + G + + + Q + K +N Sbjct: 203 MVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLN 262 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSH 313 K + ++ ++ + D L+ IGR+ +G E +GI+L+ Sbjct: 263 TKVTGATKKSDGKIDVS-IEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPR 321 Query: 314 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP 373 +I + T +PNIY++GDVV L A G + G +DY VP Sbjct: 322 GRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAV----HIDYNCVP 377 Query: 374 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 433 SVI++HPE +G SE E +++ G E KV F A A + + KI+ + Sbjct: 378 SVIYTHPEVAWVGKSE-EQLKEEGIE-YKVGKFPFAANSRAKTNADTDGMVKILGQKSTD 435 Query: 434 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 +V+G HI+G + E++ +A++ GA+ HPT +E Sbjct: 436 RVLGAHILGPGAGEMVNEAALALEYGASCEVIARVCHAHPTLSE 479 >6AON-A nrPDB Length = 478 Score = 157 bits (396), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 130/486 (26%), Positives = 226/486 (46%), Gaps = 53/486 (10%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-------KALGGTCVNVGCVPKKVMW 73 +K +D +VIG G GG +A RAA G ++A A GGTC NVGC+P K + Sbjct: 5 SKQFDVVVIGAGPGGYIAAIRAAQLGMSVACIDAWQNGQGGPAPGGTCTNVGCIPSKALL 64 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQ---KRDAYVHRLNGIYQKN---- 126 +S+ + +H H + E K K D + R N + ++N Sbjct: 65 QSSEHYEQANH---------------HFAEHGIEVKGVSLKLDTLIGRKNTVVKQNNDGI 109 Query: 127 ---LEKEKVDVVFGWARF--NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGF 181 +K KV G F DG ++ T A H++VATG A +PG Sbjct: 110 LYLFKKNKVTYFHGKGAFAGQVDGGWSIKVTGTTDADLVAKHVIVATGSSA---RELPGL 166 Query: 182 ELG----TDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD 237 +DG + PKK+ V+GAG IG+E+ V+ LG+E ++ L D Sbjct: 167 PFDEKNILSNDGALNIGAVPKKLGVIGAGVIGLEMGSVWRRLGAEVTILEAMPEFLAAAD 226 Query: 238 ECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDD---VDELIWTIG 294 + + + K+G+++ KI +++ ++ + + D+K + VD+LI +IG Sbjct: 227 QQVAKEALKSFAKQGLDIQTGVKIGEIKAAAKS--ITVPYVDAKGAEQKLVVDKLIVSIG 284 Query: 295 RKSHL-GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLS 353 R + G+ +E VG+KL+ + DE TN+PN++++GDVV L A G ++ Sbjct: 285 RVPYTGGLNAEAVGLKLDERGFVAVDEDCKTNLPNVWAVGDVVRGPMLAHKAEEEGVAVA 344 Query: 354 NRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYY 413 R+ G ++ +++ VP VI++ PE +G +E++ ++ G+E K + F A Sbjct: 345 ERIAG----QHGHVNFATVPWVIYTSPEIAWVGKTEQQ-LKAEGRE-YKAGSFPFMANGR 398 Query: 414 AMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHP 473 A + K++ ++V+G+HI+G ++E++ ++ D HP Sbjct: 399 ARALGDTTGFAKVIADAKTDEVLGVHIIGPMASELISEAVTIMEFRGAAEDIARICHAHP 458 Query: 474 TSAEEL 479 T +E + Sbjct: 459 TLSEAV 464 >4YWO-A nrPDB Length = 462 Score = 150 bits (380), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 135/473 (28%), Positives = 222/473 (46%), Gaps = 69/473 (14%) Query: 28 VIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHANE 87 +IG G+ G A+ +A G K +L+ +GGTCVNVGCVP K M Y +++ + Sbjct: 20 IIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAREVTG 79 Query: 88 YGLYQNLPLDKEHLTFNWPEFK--QKRDAYVHRLNGI-YQKNLEKEKVDVVFGWARFNKD 144 +Y P F Q++D V + Y+ L V+++ G ARF Sbjct: 80 SEVY--------------PPFSSFQEKDGLVQEMRKTKYEDLLSYYDVELIQGEARFISP 125 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEE--QPKK--- 199 V+V +V A ++ATG + P IPG D GF+ E P + Sbjct: 126 HAVKVN-----GQVIEAEKFVIATGSSPLIP-RIPGL----DKVGFWTNREALSPDRRID 175 Query: 200 -VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE------- 251 + V+G + +E A ++ + E ++ R ++ ++ + ++ + E Sbjct: 176 SLAVIGGRALALEFAQMYSRMKVEVAILQRSPVLIPDWEP--EASVEARRIMENDGVAVV 233 Query: 252 -GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKL 310 G+NV ++ K K V TDK ++ + DE++ GRK ++ +G EN G++L Sbjct: 234 TGVNVKEVRK--GAGKIVITDKGEV---------EADEILLATGRKPNVDLGLENAGVRL 282 Query: 311 NSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLS----NRLFGPEKFRNDK 366 N I D+ T+ P+IY+ GDV+G L + AGR+ S N L G K + Sbjct: 283 NERGGIKVDDELRTDNPHIYAAGDVLGGKMLEAL---AGRQGSIATENALTGSHK----R 335 Query: 367 LDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKI 426 +D VP VIF+ P +G++E EA K G+ +V +++ A + K+ Sbjct: 336 VDENAVPQVIFTQPNLARVGLTEAEARAKEGEVEARVL--PMSSVAKAEIINSRLGFVKM 393 Query: 427 VCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 V N ++VG+H VG++ AE++ +AI+ GAT D + V + PT AE L Sbjct: 394 VTM--NGRIVGVHAVGENVAEMIGEAALAIRFGATVHDLIDTVHMFPTIAESL 444 >1LVL-A nrPDB Length = 458 Score = 150 bits (378), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 132/468 (28%), Positives = 216/468 (46%), Gaps = 37/468 (7%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD-- 77 T L+IGGG GG +A RA G T+LVE +ALGGTC+N+GC+P K + + ++ Sbjct: 2 QTIQTTLLIIGGGPGGYVAAIRAGQLGIPTVLVEGQALGGTCLNIGCIPSKALIHVAEQF 61 Query: 78 -LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 A+R + + G+ P + W +D V RL L+K V VV Sbjct: 62 HQASRFTEPSPLGISVASPRLDIGQSVAW------KDGIVDRLTTGVAALLKKHGVKVVH 115 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG---TDSDGFFRL 193 GWA+ VEV + E H+L+ATG ++ +P LG S Sbjct: 116 GWAKVLDGKQVEVDGQRIQCE-----HLLLATGSSSV---ELPMLPLGGPVISSTEALAP 167 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 + P+ +VVVG GYIG+EL + LG++ +V E +L +D + + + K GI Sbjct: 168 KALPQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERILPTYDSELTAPVAESLKKLGI 227 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSID---DVDELIWTIGRKSHL-GMGSENVGIK 309 +H + E + ND K + D ++ +GR+ G E + +K Sbjct: 228 ALHLGHSVEGYENGC------LLANDGKGGQLRLEADRVLVAVGRRPRTKGFNLECLDLK 281 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 +N I DE T++ N++++GDV G+ L A+A G ++ + G + + + Sbjct: 282 MNG-AAIAIDERCQTSMHNVWAIGDVAGEPMLAHRAMAQGEMVAEIIAG----KARRFEP 336 Query: 370 ENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 + +V F+ PE +G + ++A ++ G + I V F A AM E ++V Sbjct: 337 AAIAAVCFTDPEVVVVGKTPEQASQQ-GLDCI-VAQFPFAANGRAMSLESKSGFVRVVAR 394 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 N ++G VG + +E+ F +++MGA D + HPT E Sbjct: 395 RDNHLILGWQAVGVAVSELSTAFAQSLEMGACLEDVAGTIHAHPTLGE 442 >2QAE-A nrPDB Length = 468 Score = 149 bits (376), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 126/450 (28%), Positives = 212/450 (47%), Gaps = 26/450 (5%) Query: 41 RAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYASDLATRVSHAN--EYGLYQNLPLD 97 +AA G KT VE + ALGGTC+NVGC+P K + +A+ L +HAN YGL + Sbjct: 20 KAAQLGMKTACVEKRGALGGTCLNVGCIPSKALLHATHL-YHDAHANFARYGL-----MG 73 Query: 98 KEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTE 157 E +T + + +Q+++ V L G + +K KV G F ++ V D E Sbjct: 74 GEGVTMDSAKMQQQKERAVKGLTGGVEYLFKKNKVTYYKGEGSFETAHSIRVNGLDGKQE 133 Query: 158 VYSANHILVATGGKAIFPENIPGFELG----TDSDGFFRLEEQPKKVVVVGAGYIGIELA 213 + ++ATG + P +P S G L PK +VV+G G IG+EL Sbjct: 134 MLETKKTIIATGSE---PTELPFLPFDEKVVLSSTGALALPRVPKTMVVIGGGVIGLELG 190 Query: 214 GVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK-EGINVHKLSKIVKVEKNVETDK 272 V+ LG+E +V DE + N + K E + +K+V N ++ Sbjct: 191 SVWARLGAEVTVVEFAPRCAPTLDEDVTNALVGALAKNEKMKFMTSTKVVGGTNNGDSVS 250 Query: 273 LKIH-MNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEYQNTNVPNIY 330 L++ N + + L+ ++GR+ G+G + + + N + ++ T++P++Y Sbjct: 251 LEVEGKNGKRETVTCEALLVSVGRRPFTGGLGLDKINVAKNERGFVKIGDHFETSIPDVY 310 Query: 331 SLGDVVGK-VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISE 389 ++GDVV K L A G + L G + ++Y +P+VI++ PE S+G SE Sbjct: 311 AIGDVVDKGPMLAHKAEDEGVACAEILAG----KPGHVNYGVIPAVIYTMPEVASVGKSE 366 Query: 390 KEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEIL 449 E ++K G KV F A A K++ ++++G+HIV ++ E++ Sbjct: 367 DE-LKKEGVA-YKVGKFPFNANSRAKAVSTEDGFVKVLVDKATDRILGVHIVCTTAGELI 424 Query: 450 QGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +A++ GA+ D HPT +E L Sbjct: 425 GEACLAMEYGASSEDVGRTCHAHPTMSEAL 454 >3II4-A nrPDB Length = 466 Score = 134 bits (337), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 127/466 (27%), Positives = 205/466 (43%), Gaps = 27/466 (5%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA-TR 81 HYD +V+G G GG +A RAA G T +VE K GG C+NVGC+P K + ++L Sbjct: 5 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 64 Query: 82 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 A +G+ + D + + R A VH L ++K K+ + G+ F Sbjct: 65 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGYGTF 117 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQ----- 196 + V D TE + ++ ++ATG +PG L S EEQ Sbjct: 118 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRL---VPGTSL---SANVVTYEEQILSRE 171 Query: 197 -PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 255 PK +++ GAG IG+E V G + +V L D + I + K G+ + Sbjct: 172 LPKSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTI 231 Query: 256 HKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHD 314 +K+ + + + + ++++ IG ++ G G + G+ L Sbjct: 232 LTATKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRK 291 Query: 315 QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS 374 I D+Y TNV +IY++GDV G ++L VA A G + + G E D+ +P Sbjct: 292 AIGVDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLG--DHRMLPR 349 Query: 375 VIFSHPEAGSIGISEKEAI-EKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 433 F P S G++E++A E Y ++ V FTA A K+V + Sbjct: 350 ATFCQPNVASFGLTEQQARNEGY---DVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHG 406 Query: 434 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +++G H+VG AE+L +A + T ++ V HPT +E L Sbjct: 407 ELLGGHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 452 >1ZK7-A nrPDB Length = 467 Score = 126 bits (316), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 120/438 (27%), Positives = 205/438 (46%), Gaps = 28/438 (6%) Query: 28 VIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA-TRVSHAN 86 VIG G +A+A +A GA+ L+E +GGTCVNVGCVP K+M A+ +A R Sbjct: 9 VIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPF 68 Query: 87 EYGLYQNLP-LDKEHLTFNWPEFKQKRDAYVH-RLNGIYQKNLEKEKVDVVFGWARFNKD 144 + G+ +P +D+ L + + + D H + GI N + VV G ARF D Sbjct: 69 DGGIAATVPTIDRSKL---LAQQQARVDELRHAKYEGILGGN---PAITVVHGEARFKDD 122 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGT--DSDGFFRLEEQPKKVVV 202 ++ V+ + V + LVATG P IPG + S + P+++ V Sbjct: 123 QSLTVRLNEGGERVVMFDRCLVATGASPAVPP-IPGLKESPYWTSTEALASDTIPERLAV 181 Query: 203 VGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIV 262 +G+ + +ELA F LGS+ ++ R R+ D I +T + EGI V + ++ Sbjct: 182 IGSSVVALELAQAFARLGSKVTVLARNTLFFRE-DPAIGEAVTAAFRAEGIEVLEHTQAS 240 Query: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEY 321 +V L + ++ D+L+ GR + + + G+ +N+ I+ D+ Sbjct: 241 QVAHMDGEFVLTTTHGELRA----DKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQG 296 Query: 322 QNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPE 381 T+ PNIY+ GD + + VA AAG + + + G + LD +P+V+F+ P+ Sbjct: 297 MRTSNPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDA----ALDLTAMPAVVFTDPQ 352 Query: 382 AGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTR--YKIVCAGPNEKVVGLH 439 ++G SE EA + I+ + T TR K+V + +++G+ Sbjct: 353 VATVGYSEAEA----HHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSHRLIGVQ 408 Query: 440 IVGDSSAEILQGFGVAIK 457 V + E++Q +AI+ Sbjct: 409 AVAPEAGELIQTAALAIR 426 >3L8K-A nrPDB Length = 466 Score = 111 bits (278), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 116/466 (24%), Positives = 208/466 (44%), Gaps = 34/466 (7%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLATRV 82 YD +VIG G G A R A L+ + K LGG C+ GCVP K + A R+ Sbjct: 5 YDVVVIGAGGAGYHGAFRLAKAKYNVLMADPKGELGGNCLYSGCVPSKTVREVIQTAWRL 64 Query: 83 SH-ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLN-GIYQKNLEK-EKVDVVFGWA 139 ++ AN +PLD + Q R YV L +++N+ + E + G+ Sbjct: 65 TNIAN-----VKIPLDFSTV--------QDRKDYVQELRFKQHKRNMSQYETLTFYKGYV 111 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFF----RLEE 195 + KD + K D E+ + ++ G +PG E SD F + Sbjct: 112 KI-KDPTHVIVKTDEGKEIEAETRYMIIASGAETAKLRLPGVEYCLTSDDIFGYKTSFRK 170 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLV-IRGETVLRKFDECIQNTITDHYVKEGIN 254 P+ +V++GAGYIG+E+A +F +G +TH++ + ++ D+ I NT+ +K I Sbjct: 171 LPQDMVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLEDQDIVNTLLS-ILKLNIK 229 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHD 314 + VK K+ E + + + SK + ++ GR+ + G+ +G+ + S Sbjct: 230 FNSPVTEVKKIKDDEYEVIYSTKDGSKKSIFTNSVVLAAGRRPVIPEGAREIGLSI-SKT 288 Query: 315 QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS 374 I+ DE TN+PN+++ GD G A+ +N + D +D +++P Sbjct: 289 GIVVDETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNIMA-NGMPVDYVDVKSIPV 347 Query: 375 VIFSHPEAGSIGISEKEAIEKYGKENIKV-YNSK--FTAMYYAMLSEKSPTRYKIVCAGP 431 I++ P +GI +A K G E ++ YN + +A Y + K++ Sbjct: 348 TIYTIPSLSYVGILPSKA-RKMGIEIVEAEYNMEEDVSAQIYG----QKEGVLKLIFERG 402 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 + +++G ++G S ++ G+A+ G + HP++ E Sbjct: 403 SMRLIGAWMIGVHSQYLINELGLAVAYGLNAKQLASFAEQHPSTNE 448 >3IC9-A nrPDB Length = 492 Score = 108 bits (271), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 99/387 (25%), Positives = 181/387 (46%), Gaps = 22/387 (5%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSH 84 D +IG G+ G+ + R A + K +L+E A G TC VGC+P K++ A+D + S Sbjct: 10 DVAIIGTGTAGMGAYRAAKKHTDKVVLIEGGAYGTTCARVGCMPSKLLIAAADASYHASQ 69 Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEK-EKVDVVFGWARFNK 143 + +G + + ++ N ++ R G +++E ++ D + G+A+F Sbjct: 70 TDLFG------IQVDRISVNGKAVMKRIQTERDRFVGFVVESVESFDEQDKIRGFAKFLD 123 Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENI--PGFELGTDSDGFFRLEEQPKKVV 201 + ++V D+ ++V A I++ATG + +PE + G L T+ D F L + PK V Sbjct: 124 EHTLQV---DDHSQVI-AKRIVIATGSRPNYPEFLAAAGSRLLTN-DNLFELNDLPKSVA 178 Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKI 261 V G G IG+EL LG + R +V DE ++ + +E K I Sbjct: 179 VFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTFNEEFYFDAKARVI 238 Query: 262 VKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQIIADE 320 +EK + + + K+ + ++ GRK+++ +G EN I+L+ + + DE Sbjct: 239 STIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNSPLFDE 298 Query: 321 YQ-NTNVPNIYSLGDVVGKVELTPVAIAAGRKL-SNRLFGPEKFRNDKLDYENVP-SVIF 377 T+V +I+ GD + L A G+ +N P + + P SV+F Sbjct: 299 LTLQTSVDHIFVAGDANNTLTLLHEAADDGKVAGTNAGAYPVIAQGQR----RAPLSVVF 354 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVY 404 + P+ S+G+S ++ + Y ++ Y Sbjct: 355 TEPQVASVGLSLRQIEDLYADQDAANY 381 >1XDI-A nrPDB Length = 499 Score = 99.8 bits (247), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 108/463 (23%), Positives = 189/463 (40%), Gaps = 31/463 (6%) Query: 27 LVIGGGSGGVASARRAASYGAKTL---LVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 +++GGG G +A AA+ +T +++ +GG V CVP K ++ L T + Sbjct: 6 VILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRTELR 65 Query: 84 HANEYGLY-----QNLPLDKEHLTFNWPEFKQKRDAYVHRLN-GIYQKNLEKEKVDVVFG 137 A G + + L + H Q D L+ G+ E +D G Sbjct: 66 RAPHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELIDSTPG 125 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKA-IFPENIPGFELGTDSDGFFRLEEQ 196 AR ++ D +T + A+ +LVATG I P P E + L+ Sbjct: 126 LARHR----IKATAADGSTSEHEADVVLVATGASPRILPSAQPDGERILTWRQLYDLDAL 181 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 P ++VVG+G G E + LG +V + VL D + + + + G+ + Sbjct: 182 PDHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAERGVRLF 241 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQ 315 K ++ V + + + M D ++++ L+ TIG + G+G E VGI+L + Sbjct: 242 KNARAASVTRT--GAGVLVTMTDGRTVEGSHALM-TIGSVPNTSGLGLERVGIQLGRGNY 298 Query: 316 IIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFG----PEKFRNDKLDYEN 371 + D T IY+ GD G + L VA GR G P + R Sbjct: 299 LTVDRVSRTLATGIYAAGDCTGLLPLASVAAMQGRIAMYHALGEGVSPIRLR-------T 351 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 V + +F+ PE ++G+ +++ G + A +SE KI C Sbjct: 352 VAATVFTRPEIAAVGV--PQSVIDAGSVAARTIMLPLRTNARAKMSEMRHGFVKIFCRRS 409 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPT 474 V+G +V ++E++ VA++ T + +A++P+ Sbjct: 410 TGVVIGGVVVAPIASELILPIAVAVQNRITVNELAQTLAVYPS 452 >1OJT-A nrPDB Length = 482 Score = 99.8 bits (247), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 118/457 (25%), Positives = 200/457 (43%), Gaps = 27/457 (5%) Query: 37 ASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL-YQNL 94 ++A AA G K +VE K LGG C+NVGC+P K + + + + V H G+ Y Sbjct: 20 SAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPEP 79 Query: 95 PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEV----- 149 LD + L + +D V RL G + KVDV+ G +F ++EV Sbjct: 80 ELDIDML-------RAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAG 132 Query: 150 ---QKRDNTTE--VYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVG 204 ++ T E + + + ++A G + IP DS G L+E P K++++G Sbjct: 133 DAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIG 192 Query: 205 AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKV 264 G IG+E+ V+ LGS +V + +++ D + N+ +K V V Sbjct: 193 GGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAV 252 Query: 265 EKNVETDKLKIH-MNDSKSIDDVDELIWTIGRKSHLGM-GSENVGIKLNSHDQIIADEYQ 322 E + + N K D ++ GR + + +E G+ + I D+ Sbjct: 253 EPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQM 312 Query: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382 TNVP+IY++GD+VG+ L A+ G + G + + D +P V ++ PE Sbjct: 313 RTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAY----FDARVIPGVAYTSPEV 368 Query: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG 442 +G +E A K I N + A A+ + K++ +++G IVG Sbjct: 369 AWVGETELSA--KASARKITKANFPWAASGRAIANGCDKPFTKLIFDAETGRIIGGGIVG 426 Query: 443 DSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 + +++ +AI+MG AD + HPT E + Sbjct: 427 PNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESI 463 >5U25-A nrPDB Length = 602 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 118/457 (25%), Positives = 200/457 (43%), Gaps = 27/457 (5%) Query: 37 ASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL-YQNL 94 ++A AA G K +VE K LGG C+NVGC+P K + + + + V H G+ Y Sbjct: 139 SAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPEP 198 Query: 95 PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEV----- 149 LD + L + +D V RL G + KVDV+ G +F ++EV Sbjct: 199 ELDIDML-------RAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAG 251 Query: 150 ---QKRDNTTE--VYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVG 204 ++ T E + + + ++A G + IP DS G L+E P K++++G Sbjct: 252 DAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIG 311 Query: 205 AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKV 264 G IG+E+ V+ LGS +V + +++ D + N+ +K V V Sbjct: 312 GGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAV 371 Query: 265 EKNVETDKLKIH-MNDSKSIDDVDELIWTIGRKSHLGM-GSENVGIKLNSHDQIIADEYQ 322 E + + N K D ++ GR + + +E G+ + I D+ Sbjct: 372 EPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQM 431 Query: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382 TNVP+IY++GD+VG+ L A+ G + G + + D +P V ++ PE Sbjct: 432 RTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHKAY----FDARVIPGVAYTSPEV 487 Query: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG 442 +G +E A K I N + A A+ + K++ +++G IVG Sbjct: 488 AWVGETELSA--KASGRKITKANFPWAASGRAIANGCDNGFTKLIFDAETGRIIGGGIVG 545 Query: 443 DSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 + +++ +AI+MG AD + HPT E + Sbjct: 546 PNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESI 582 >3Q6J-A nrPDB Length = 523 Score = 91.7 bits (226), Expect = 7e-19, Method: Compositional matrix adjust. Identities = 114/502 (22%), Positives = 215/502 (42%), Gaps = 65/502 (12%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDL 78 + + YD + IGGG+ G + + G + L+V+ LGG+C + CVP + SD Sbjct: 40 DPREYDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPHHLF---SDC 96 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ-KNLE-KEKVDVVF 136 A + A + P E + K+ D + NG + N + KE++++ + Sbjct: 97 AAELMLARTFSGQYWFPDMTEKVV----GIKEVVDLFRAGRNGPHGIMNFQSKEQLNLEY 152 Query: 137 GWARFNKDGNVEVQKRDNTT-----EVYSANHILVATG-GKAIFPENIPGFELGTDSDGF 190 N + DN T +V+ A ++++A G G ++PG ++ G Sbjct: 153 IL-------NCPAKVIDNHTVEAAGKVFKAKNLILAVGAGPGTL--DVPG----VNAKGV 199 Query: 191 F-------RLEEQP-KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQN 242 F L+ +P VVVVG +E F+ G T +++R E + D + Sbjct: 200 FDHATLVEELDYEPGSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLIKDNETRA 259 Query: 243 TITDHYVKEGINVHKLSKIVKVEK--NVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 + D ++G+ + S + ++E+ N + + + + D + +G + Sbjct: 260 YVLDRMKEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMRIETDFVFLGLGEQPRSA 319 Query: 301 MGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPE 360 ++ +G+ L +++ +EY T+VPN+Y++GD++G P+ + RK + + Sbjct: 320 ELAKILGLDLGPKGEVLVNEYLQTSVPNVYAVGDLIGG----PMEMFKARK--SGCYAAR 373 Query: 361 KFRNDKLDY--ENVPSVIFSHPEAGSIGISEKEAIEKYGKE--------------NIKVY 404 +K+ Y +N P + +H E +G+ E+EA G E N+ + Sbjct: 374 NVMGEKISYTPKNYPDFLHTHYEVSFLGMGEEEA-RAAGHEIVTIKMPPDTENGLNVALP 432 Query: 405 NSKFTAMY-YAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKA 463 S T +Y + + KIV KV+G H VG + + Q V IK G T Sbjct: 433 ASDRTMLYAFGKGTAHMSGFQKIVIDAKTRKVLGAHHVGYGAKDAFQYLNVLIKQGLTVD 492 Query: 464 DFDNC--VAIHPTSAEELVTMR 483 + + + ++PT +L +R Sbjct: 493 ELGDMDELFLNPTHFIQLSRLR 514 >2BC1-A nrPDB Length = 490 Score = 59.7 bits (143), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 96/203 (47%), Gaps = 27/203 (13%) Query: 153 DNTTEVYSANHILVATGGKAIFP------------------ENIPGFELGTDS-DGFFRL 193 D V + + ++ ATG + I P EN+ +L +S D +L Sbjct: 130 DGKNHVETYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVIAKL 189 Query: 194 EEQP-KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRK-FDECIQNTITDHYVKE 251 E + K+V VVGAGYIG+ELA F G E L+ +T L +D + + + + + Sbjct: 190 ENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEH 249 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLN 311 GI + + +V N + +K+ N+ DVD +I +G + + +G N I L Sbjct: 250 GIQLAFGETVKEVAGNGKVEKIITDKNEY----DVDMVILAVGFRPNTTLG--NGKIDLF 303 Query: 312 SHDQIIADEYQNTNVPNIYSLGD 334 + + ++ Q T++P +Y++GD Sbjct: 304 RNGAFLVNKRQETSIPGVYAIGD 326 >3ICS-A nrPDB Length = 588 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 20/210 (9%) Query: 140 RFNKDGNVEVQKRDNTTEVYSANH--ILVATGGKAIFPENIPGFELG-----------TD 186 + NK+ K T E Y+ + ++++ G K I P +IPG E TD Sbjct: 118 KINKEEKTITIKNVTTNETYNEAYDVLILSPGAKPIVP-SIPGIEEAKALFTLRNVPDTD 176 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD 246 + E++P+ V+G G+IG+E+ G E LV V+ D + + + Sbjct: 177 RIKAYIDEKKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVMPPIDYEMAAYVHE 236 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENV 306 H + + + +E+N +LK S S+ D LI IG + + ++ Sbjct: 237 HMKNHDVELVFEDGVDALEENGAVVRLK-----SGSVIQTDMLILAIGVQPESSL-AKGA 290 Query: 307 GIKLNSHDQIIADEYQNTNVPNIYSLGDVV 336 G+ L I +E T+ P+IY++GD + Sbjct: 291 GLALGVRGTIKVNEKFQTSDPHIYAIGDAI 320 >3IWA-A nrPDB Length = 472 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 66/288 (22%), Positives = 126/288 (43%), Gaps = 23/288 (7%) Query: 199 KVVVVGAGYIGIELAGVFHGL-GSETHLVIRGETVLRKFDECIQNTITDHYV-KEGINVH 256 K V+VG G+IG+E+A + G +T +V + ++ F + + H + K + VH Sbjct: 161 KAVIVGGGFIGLEMAVSLADMWGIDTTVVELADQIMPGFTSKSLSQMLRHDLEKNDVVVH 220 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQI 316 K+V++E E K+ + D +++ D D +I G + + + + G++L+ I Sbjct: 221 TGEKVVRLEG--ENGKVARVITDKRTL-DADLVILAAGVSPNTQL-ARDAGLELDPRGAI 276 Query: 317 IADEYQNTNVPNIYSLGD-------VVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 I D T+ P+I++ GD V GK P+ A R+ R+ G D Sbjct: 277 IVDTRMRTSDPDIFAGGDCVTIPNLVTGKPGFFPLGSMANRQ--GRVIGTNLADGDATFP 334 Query: 370 ENVPS--VIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIV 427 V S V A G++ + A+ + G + + V+ +F ++ EK+ ++V Sbjct: 335 GAVGSWAVKLFEGSASGAGLTVEGAL-REGYDAVNVHVEQFDRAHF--YPEKTIMTLQLV 391 Query: 428 CAGPNEKVVGLH---IVGDSSAEILQGFGVAIKMGATKADFDNCVAIH 472 P +V+G+ +GD+ + + T D N ++ Sbjct: 392 VDRPTRRVLGIQGFSTLGDALTARINAVATMLASKPTVEDISNAEVVY 439 >2CDU-A nrPDB Length = 452 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 52/188 (27%), Positives = 85/188 (45%), Gaps = 17/188 (9%) Query: 156 TEVYSANHILVATGGKAIFPENIPGFELG--------TDSDGFFRLEEQPKKVVVVGAGY 207 TE Y + +++ TG K P IPG + D+ F + K + ++G+GY Sbjct: 103 TEAY--DKLIMTTGSKPTVPP-IPGIDSSRVYLCKNYNDAKKLFEEAPKAKTITIIGSGY 159 Query: 208 IGIELAGVFHGLGSETHLVIRGETVLRK-FDECIQNTITDHYVKEGINVHKLSKIVKVEK 266 IG ELA + +L+ E VL K FD+ + + Y G+N+ SK+ E+ Sbjct: 160 IGAELAEAYSNQNYNVNLIDGHERVLYKYFDKEFTDILAKDYEAHGVNLVLGSKVAAFEE 219 Query: 267 NVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNV 326 D++ D K I D I IG + + + V + N II DEY +++ Sbjct: 220 --VDDEIITKTLDGKEIKS-DIAILCIGFRPNTELLKGKVAMLDNG--AIITDEYMHSSN 274 Query: 327 PNIYSLGD 334 +I++ GD Sbjct: 275 RDIFAAGD 282 >5ER0-A nrPDB Length = 518 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 61/251 (24%), Positives = 107/251 (42%), Gaps = 38/251 (15%) Query: 97 DKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTT 156 D + L ++ PE QK A V + + + +++ V V ++ TT Sbjct: 104 DPQGLFYSSPEELQKLGANVQMNHNVLAIDPDQKTVTVE------------DLTNHAQTT 151 Query: 157 EVYSANHILVATGGKAIFPENIPGFELGTDSD------------GFFRLEEQPKKVVVVG 204 E Y + +++ +G I P+ IPG DSD ++ K++ V+G Sbjct: 152 ESY--DKLVMTSGSWPIVPK-IPGI----DSDRVKLCKNWAHAQALIEDAKEAKRITVIG 204 Query: 205 AGYIGIELAGVFHGLGSETHLVIRGETVLRK-FDECIQNTITDHYVKEGINVHKLSKIVK 263 AGYIG ELA + G + L+ V+ K FD + I Y G+ + L + V+ Sbjct: 205 AGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHGVQL-ALGETVE 263 Query: 264 VEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQN 323 + T + + K+ + D I IG + + + V + N II D+Y Sbjct: 264 SFTDSAT---GLTIKTDKNSYETDLAILCIGFRPNTDLLKGKVDMAPNG--AIITDDYMR 318 Query: 324 TNVPNIYSLGD 334 ++ P+I++ GD Sbjct: 319 SSNPDIFAAGD 329 >4FX9-A nrPDB Length = 453 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 77/323 (23%), Positives = 141/323 (43%), Gaps = 58/323 (17%) Query: 99 EHLTFNWPE-FKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTE 157 + L + PE F +KR +H L E ++V G+ R ++G + Sbjct: 61 DKLMYYPPEVFIKKRGIDLH---------LNAEVIEVDTGYVRVRENGG---------EK 102 Query: 158 VYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQP--------------KKVVVV 203 Y ++++ A G +P E G + G F + P + VV++ Sbjct: 103 SYEWDYLVFANGASP----QVPAIE-GVNLKGVFTADLPPDALAIREYMEKYKVENVVII 157 Query: 204 GAGYIGIELAGVFHGLGSETHLVIRGETVLRK-FDECIQNTITDHYVKEGINVHKLSKIV 262 G GYIGIE+A F G +++RGE VLR+ FD+ + + I + +K+ +N+ + Sbjct: 158 GGGYIGIEMAEAFAAQGKNVTMIVRGERVLRRSFDKEVTD-ILEEKLKKHVNLRLQEITM 216 Query: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQ 322 K+E +K+ + K+ + +I G K ++ + ++ +G+++ I +E Sbjct: 217 KIEGEERVEKVVTDAGEYKA----ELVILATGIKPNIEL-AKQLGVRIGETGAIWTNEKM 271 Query: 323 NTNVPNIYSLGDV-------VGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSV 375 T+V N+Y+ GDV G+ P+A AG K+ +L + V Sbjct: 272 QTSVENVYAAGDVAETRHVITGRRVWVPLA-PAGNKMG--YVAGSNIAGKELHFPGVLGT 328 Query: 376 I---FSHPEAGSIGISEKEAIEK 395 F E G G++E EA+++ Sbjct: 329 AVTKFMDVEIGKTGLTEMEALKE 351 >3NTA-A nrPDB Length = 574 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 45/186 (24%), Positives = 83/186 (44%), Gaps = 27/186 (14%) Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKI 261 VVG G+IG+E+ H LG +T L+ + V+ D + +G+++ + + Sbjct: 156 VVGGGFIGLEMMESLHHLGIKTTLLELADQVMTPVDREMAGFAHQAIRDQGVDLRLGTAL 215 Query: 262 VKVEKNVET-------------DKLKIHMNDSKS---IDDVDELIWTIGRKSHLGMGSEN 305 +V V+T +K H++ + S + + D LI IG + + + + Sbjct: 216 SEVSYQVQTHVASDAAGEDTAHQHIKGHLSLTLSNGELLETDLLIMAIGVRPETQL-ARD 274 Query: 306 VGIKLNSHDQIIADEYQNTNVPNIYSLGD-------VVGKVELTPVAIAA---GRKLSNR 355 G+ + I + T+ P IY++GD V G+ L P+A A GR ++ Sbjct: 275 AGLAIGELGGIKVNAMMQTSDPAIYAVGDAVEEQDFVTGQACLVPLAGPANRQGRMAADN 334 Query: 356 LFGPEK 361 +FG E+ Sbjct: 335 MFGREE 340 >1YQZ-A nrPDB Length = 438 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 8/151 (5%) Query: 185 TDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 TD+ F Q KV+VVGAGY+ +E+ + G L+ R + + + D + I Sbjct: 136 TDAIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPI 195 Query: 245 TDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSE 304 D K I +I + N T K S ++ D +I +G + E Sbjct: 196 LDELDKREIPYRLNEEINAINGNEITFK-------SGKVEHYDMIIEGVGTHPNSKF-IE 247 Query: 305 NVGIKLNSHDQIIADEYQNTNVPNIYSLGDV 335 + IKL+ I ++ TNVPNIY++GD+ Sbjct: 248 SSNIKLDRKGFIPVNDKFETNVPNIYAIGDI 278 >3CGD-A nrPDB Length = 480 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 85/191 (44%), Gaps = 26/191 (13%) Query: 159 YSANHILVATGGKAIFPE----NIPGFELGT---DSDGFFRLEEQPK--KVVVVGAGYIG 209 +S + +L+ATG + + PE ++ G L D++ + E K V ++G G IG Sbjct: 139 FSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIG 198 Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFD----ECIQNTITDHYVK--EGINVHKLSKIVK 263 +E+A F LG + ++ R + + +D E I H+++ NV + Sbjct: 199 LEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHIEILTNENVKAFKGNER 258 Query: 264 VEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQN 323 VE VETD K D ++ ++G K + E I+ N I + Y Sbjct: 259 VEA-VETD---------KGTYKADLVLVSVGVKPNTDF-LEGTNIRTNHKGAIEVNAYMQ 307 Query: 324 TNVPNIYSLGD 334 TNV ++Y+ GD Sbjct: 308 TNVQDVYAAGD 318 >3OC4-A nrPDB Length = 452 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 57/244 (23%), Positives = 102/244 (41%), Gaps = 25/244 (10%) Query: 116 VHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQ----KRDNTTEVYSANHILVATGGK 171 +H I ++ L ++K+ ++ D VE Q R + YS + +++ATG Sbjct: 57 LHEARYITEEELRRQKIQLLLNREVVAMD--VENQLIAWTRKEEQQWYSYDKLILATGAS 114 Query: 172 AIFPENIPG--------FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSET 223 F I G ++ + + L E + V V+GAG IG+E + Sbjct: 115 Q-FSTQIRGSQTEKLLKYKFLSGALAAVPLLENSQTVAVIGAGPIGMEAIDFLVKMKKTV 173 Query: 224 HLVIRGETVLRK-FDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS 282 H+ E +L K FD+ + + K+ + H ++ +E+ I + S+ Sbjct: 174 HVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETAN----GIVLETSEQ 229 Query: 283 IDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIA-DEYQNTNVPNIYSLGDVVGKVEL 341 D I+ + L + + L DQ IA D Y T+VPN++++GD + + Sbjct: 230 EISCDSGIFALNLHPQLAYLDKKIQRNL---DQTIAVDAYLQTSVPNVFAIGDCISVMN- 285 Query: 342 TPVA 345 PVA Sbjct: 286 EPVA 289 >2YVG-A nrPDB Length = 408 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 57/262 (21%), Positives = 96/262 (36%), Gaps = 50/262 (19%) Query: 91 YQNLPLDKEHLTFNWPE---FKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNV 147 Y PL K+ + E KR V L G+ ++ + + V Sbjct: 46 YDRPPLSKDFMAHGDAEKIRLDCKRAPEVEWLLGVTAQSFDPQAHTVALS---------- 95 Query: 148 EVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKV------- 200 D T Y +++ATG P +P + T R E +++ Sbjct: 96 -----DGRTLPY--GTLVLATGAA---PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQ 145 Query: 201 ---VVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD----HYVKEGI 253 ++VG G IG+ELA G LV ET R T+ D ++ +G+ Sbjct: 146 SRLLIVGGGVIGLELAATARTAGVHVSLV---ETQPRLMSRAAPATLADFVARYHAAQGV 202 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 ++ + E++V + + D + D ++ IG ++ + L Sbjct: 203 DL-------RFERSVTGSVDGVVLLDDGTRIAADMVVVGIGVLANDALAR---AAGLACD 252 Query: 314 DQIIADEYQNTNVPNIYSLGDV 335 D I D Y T P++Y+LGDV Sbjct: 253 DGIFVDAYGRTTCPDVYALGDV 274 >3AB1-A nrPDB Length = 360 Score = 42.0 bits (97), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 68/247 (27%), Positives = 115/247 (46%), Gaps = 42/247 (17%) Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG-----TDSDGFFRLEE--- 195 DG E R NT VY + +L+A G A P +P +LG T S ++ ++ Sbjct: 105 DGTFET--RTNTGNVYRSRAVLIAAGLGAFEPRKLP--QLGNIDHLTGSSVYYAVKSVED 160 Query: 196 -QPKKVVVVGAGYIGIELA-GVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG- 252 + K+VV+VG G ++ G+ S T LV RG E + T H V+ Sbjct: 161 FKGKRVVIVGGGDSALDWTVGLIKNAASVT-LVHRGH-------EFQGHGKTAHEVERAR 212 Query: 253 ----INVHKLSKIVKVEK-NVETDKLKIHMND-SKSIDDVDELIWTIGRKSHLG-MGSEN 305 I+V+ +++ +E+ N ++ + +D SK + D L+ IG KS+LG + + Sbjct: 213 ANGTIDVYLETEVASIEESNGVLTRVHLRSSDGSKWTVEADRLLILIGFKSNLGPLARWD 272 Query: 306 VGIKLNSHDQIIADEYQNTNVPNIYSLGDVV---GKVE-----LTPVAIAAGRKLSNRLF 357 + + N+ ++ D + T+V +Y+ GD+ GK++ L+ +A LS Sbjct: 273 LELYENA---LVVDSHMKTSVDGLYAAGDIAYYPGKLKIIQTGLSEATMAVRHSLSYIKP 329 Query: 358 GPEKFRN 364 G EK RN Sbjct: 330 G-EKIRN 335 >1Q1R-A nrPDB Length = 431 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 37/171 (21%), Positives = 78/171 (45%), Gaps = 14/171 (8%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE-GINVHK 257 ++VV+G GYIG+E+A L+ VL + + +H +E G+++ Sbjct: 151 RLVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRT 210 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII 317 +++ E + + K+ + + + D +I IG + + S G++++ + I+ Sbjct: 211 GTQVCGFEMSTDQQKVTAVLCEDGTRLPADLVIAGIGLIPNCELASA-AGLQVD--NGIV 267 Query: 318 ADEYQNTNVPNIYSLGDVVG----------KVELTPVAIAAGRKLSNRLFG 358 +E+ T+ P I ++GD ++E P A+ RK++ L G Sbjct: 268 INEHMQTSDPLIMAVGDCARFHSQLYDRWVRIESVPNALEQARKIAAILCG 318 >5JCN-A nrPDB Length = 451 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/138 (23%), Positives = 61/138 (44%), Gaps = 5/138 (3%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDHYVKEGINVHK 257 K V+VG GYIG+EL+ + +V + R F I +Y +G+ + K Sbjct: 182 KAVIVGGGYIGLELSAALKINDFDVTMVFPEPWCMPRLFTADIAAFYESYYTNKGVKIVK 241 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII 317 + V + + D +++ + S+ + D ++ +G + + V I Sbjct: 242 GTVAVGFDADANGDVTAVNLKNG-SVLEADIVVVGVGGRPLTTLFKGQVA---EEKGGIK 297 Query: 318 ADEYQNTNVPNIYSLGDV 335 D + T+VP +Y++GDV Sbjct: 298 TDAFFETSVPGVYAVGDV 315 >4YRY-B nrPDB Length = 468 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 56/221 (25%), Positives = 91/221 (41%), Gaps = 34/221 (15%) Query: 154 NTTEVYSANHIL--VATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIE 211 N VYSAN L V +FPE +G KKV V+GAG ++ Sbjct: 247 NLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVG-------------KKVAVIGAGNTAMD 293 Query: 212 LAGVFHGLGSETHLVIRGET-------------VLRKFDECIQNTITDHYVKEGINVHKL 258 A LG+E ++ T L + E + T+ Y+ + + Sbjct: 294 AARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEA 353 Query: 259 SKIVKVEKNVETD----KLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHD 314 + V++E E D + + S + +VD +I IG+ + + SE G++LN Sbjct: 354 MECVRMELK-EADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERG 412 Query: 315 QIIADEYQN-TNVPNIYSLGDVVGKVELTPVAIAAGRKLSN 354 I ADE T+V +++ GD+V A+ AG+K + Sbjct: 413 YIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQ 453 >1NHQ-A nrPDB Length = 447 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 41/183 (22%), Positives = 79/183 (43%), Gaps = 21/183 (11%) Query: 165 LVATGGKAIFPENIPGFELGTDSDGFFR------------LEEQPKKVVVVGAGYIGIEL 212 L+ + G F +IPG +L D+ R ++ + VVV+G+GYIGIE Sbjct: 107 LIISPGAVPFELDIPGKDL--DNIYLMRGRQWAIKLKQKTVDPEVNNVVVIGSGYIGIEA 164 Query: 213 AGVFHGLGSETHLV-IRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETD 271 A F G + ++ I + D+ + +T+ I + + + E + Sbjct: 165 AEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIATGETVERYEGDGRVQ 224 Query: 272 KLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYS 331 K+ N D D ++ +G + + ++L+ + I DEY T+ P++++ Sbjct: 225 KVVTDKNAY----DADLVVVAVGVRPNTAWLKGT--LELHPNGLIKTDEYMRTSEPDVFA 278 Query: 332 LGD 334 +GD Sbjct: 279 VGD 281 >1F6M-A nrPDB Length = 320 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 79/346 (22%), Positives = 128/346 (36%), Gaps = 84/346 (24%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 80 TKH L++G G G +A AA + +L+ GG V Sbjct: 3 TKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEV------------- 49 Query: 81 RVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWAR 140 +N P D LT P ++ ++ K + +++F Sbjct: 50 -----------ENWPGDPNDLT--GPLLMER-----------MHEHATKFETEIIFD--H 83 Query: 141 FNKDGNVEVQKR------DNTTEVYSANHILVATGGKAIFPENIP--------GFELGTD 186 NK V++Q R DN Y+ + +++ATG A + +P G Sbjct: 84 INK---VDLQNRPFRLNGDNGE--YTCDALIIATGASARYL-GLPSEEAFKGRGVSASAT 137 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLV-----IRGETVL--RKFDEC 239 DGFF + +KV V+G G +E A + SE HL+ R E +L R D+ Sbjct: 138 CDGFFY---RNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKV 194 Query: 240 IQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMN-DSKSIDDVDELIWTIGRKSH 298 I H + L ++ + V +L+ N D+ DV L IG + Sbjct: 195 ENGNIILHTNR------TLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPN 248 Query: 299 LGMGS-----ENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKV 339 + EN IK+ S I T++P +++ GDV+ + Sbjct: 249 TAIFEGQLELENGYIKVQSG---IHGNATQTSIPGVFAAGDVMDHI 291 >3LXD-A nrPDB Length = 415 Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 68/154 (44%), Gaps = 13/154 (8%) Query: 186 DSDGFF-RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 D+D L+ K VV+G GYIG+E A V G L+ E + R + Sbjct: 140 DADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLL---EALPRVLARVAGEAL 196 Query: 245 TDHYVKE----GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 ++ Y E G+++ + + +E + T + M D S+ D +I IG +G Sbjct: 197 SEFYQAEHRAHGVDLRTGAAMDCIEGD-GTKVTGVRMQDG-SVIPADIVIVGIGIVPCVG 254 Query: 301 MGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGD 334 + + + + DE+ T++ ++Y++GD Sbjct: 255 A---LISAGASGGNGVDVDEFCRTSLTDVYAIGD 285 >1NAA-A nrPDB Length = 541 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 19/44 (43%), Positives = 26/44 (59%), Gaps = 5/44 (11%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-----AKALGGTCV 62 YDY+++G G GG+ +A R + G K LL+E K GGT V Sbjct: 3 YDYIIVGAGPGGIIAADRLSEAGKKVLLLERGGPSTKQTGGTYV 46 >4GCM-A nrPDB Length = 312 Score = 37.0 bits (84), Expect = 0.018, Method: Compositional matrix adjust. Identities = 69/323 (21%), Positives = 122/323 (37%), Gaps = 61/323 (18%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVN---VGCVPKKVMWYASDLAT 80 +D +IG G G+ +A A+ KT+++E GG N V P M DL+T Sbjct: 7 FDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLST 66 Query: 81 RV-SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG-- 137 ++ HA ++G + + + K D +++ K L + V + G Sbjct: 67 KMFEHAKKFG-----------AVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAE 115 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQP 197 + + G E+ R ++ V G FF+ Sbjct: 116 YKKIGVPGEQELGGR-------GVSYCAVCDG-------------------AFFK----N 145 Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLV-----IRGETVLRKFDECIQNTITDHYVKEG 252 K++ V+G G +E + +V +R + +L+ D +N D Sbjct: 146 KRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQ--DRAFKNDKIDF----- 198 Query: 253 INVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNS 312 I H L I + + V + L + S+ + D + IG K L +++GI N Sbjct: 199 IWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKP-LTAPFKDLGI-TND 256 Query: 313 HDQIIADEYQNTNVPNIYSLGDV 335 I+ + T+VP I++ GDV Sbjct: 257 VGYIVTKDDMTTSVPGIFAAGDV 279 >3BHF-A nrPDB Length = 390 Score = 36.6 bits (83), Expect = 0.024, Method: Compositional matrix adjust. Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 3/38 (7%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 MST H+D +V+G GS G+A+ + A G KTLLV+A Sbjct: 1 MST---HFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDA 35 >5UWY-A nrPDB Length = 308 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 85/344 (24%), Positives = 142/344 (41%), Gaps = 76/344 (22%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 YD L+IG G G+ +A AA ++E A GG N + Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGGQMNNTFDI---------------- 48 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA-RFN 142 +N P +H++ PE K +Y+ LEK V+ ++G + Sbjct: 49 --------ENYP-GYDHIS--GPELAMK----------MYEP-LEKFNVENIYGIVQKIE 86 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTD--------SDG-FFRL 193 G+ + ++ + Y A +++ATG K +PG E T DG FFR Sbjct: 87 NFGDYKCVLTEDAS--YEAKTVIIATGAKYRVL-GVPGEEYYTSRGVSYCAVCDGAFFRD 143 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLV-----IRGETVL--RKFDECIQNTITD 246 ++ ++VVG G +E A + +V +R + +L R F + I D Sbjct: 144 QD----LLVVGGGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKILQDRAFANDKVDFIWD 199 Query: 247 HYVKE-GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSEN 305 VKE N K+S ++ +NV+T ++ H I +G GM ++ Sbjct: 200 SVVKEIQGNDIKVSNVLI--ENVKTGQVTDHAFGGVFI--------YVGMNPVTGM-VKD 248 Query: 306 VGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAG 349 + I +S II D++ T++P I+++GDV K +L + A G Sbjct: 249 LEIT-DSEGWIITDDHMRTSIPGIFAIGDVRQK-DLRQITTAVG 290 >3MJ4-A nrPDB Length = 397 Score = 36.6 bits (83), Expect = 0.028, Method: Compositional matrix adjust. Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 8/57 (14%) Query: 15 RTMSTNT-------KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVN 63 RT TNT K +DYL++G G G A R AS G + L+V+ + +GG + Sbjct: 14 RTEQTNTTNEQQESKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYD 70 >2V3B-A nrPDB Length = 384 Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust. Identities = 53/226 (23%), Positives = 94/226 (41%), Gaps = 28/226 (12%) Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKA---IFPENIPGFELGTDSDGFFRLEEQP---K 198 G EV+ RD + A I V G A ++P N D + + R + + Sbjct: 96 GEEEVRYRD-LVLAWGAEPIRVPVEGDAQDALYPIN--------DLEDYARFRQAAAGKR 146 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKF-DECIQNTITDHYVKEGINVHK 257 +V+++GAG IG E A G + +V E V+ + G+ H Sbjct: 147 RVLLLGAGLIGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFHL 206 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII 317 + ++K E L+ H++D + I D ++ +G + + + G+ +N I+ Sbjct: 207 GPVLASLKKAGE--GLEAHLSDGEVIP-CDLVVSAVGLRPRTEL-AFAAGLAVNRG--IV 260 Query: 318 ADEYQNTNVPNIYSLGDV-----VGKVELTPVAIAAGRKLSNRLFG 358 D T+ NIY+LGD + + + P+ +A R L+ L G Sbjct: 261 VDRSLRTSHANIYALGDCAEVDGLNLLYVMPL-MACARALAQTLAG 305 >2ZBW-A nrPDB Length = 335 Score = 35.8 bits (81), Expect = 0.046, Method: Compositional matrix adjust. Identities = 69/276 (25%), Positives = 118/276 (42%), Gaps = 43/276 (15%) Query: 94 LPLDKEHLTFNWPEFKQKRDAYVHRLNG---IYQKNLEKEKVDVVFGWARFNK----DGN 146 LP LT +PE Y++ + G +Y K+L K V+ V A FN Sbjct: 37 LPEPGGQLTALYPE------KYIYDVAGFPKVYAKDLVKGLVEQV---APFNPVYSLGER 87 Query: 147 VEVQKRDN-----TTE---VYSANHILVATGGKAIFPENI--PGFELGTDSDGFF----- 191 E +R+ TT Y+A +++A G A P I PG E + G + Sbjct: 88 AETLEREGDLFKVTTSQGNAYTAKAVIIAAGVGAFEPRRIGAPG-EREFEGRGVYYAVKS 146 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 + E Q K+V++VG G ++ A L+ R R + ++ + H +E Sbjct: 147 KAEFQGKRVLIVGGGDSAVDWALNLLDTARRITLIHR-RPQFRAHEASVKELMKAH--EE 203 Query: 252 G-INVHKLSKIVKVEKNVETDKLKIHMNDSKS--IDDVDELIWTIGRKSHLGMGSENVGI 308 G + V ++ +VE + + N ++ +VD ++ G + LG + N G+ Sbjct: 204 GRLEVLTPYELRRVEGDERVRWAVVFHNQTQEELALEVDAVLILAGYITKLGPLA-NWGL 262 Query: 309 KLNSHDQIIADEYQNTNVPNIYSLGDVV---GKVEL 341 L ++I D T++P +Y+ GD+V GK+ L Sbjct: 263 ALEK-NKIKVDTTMATSIPGVYACGDIVTYPGKLPL 297 >5MJK-A nrPDB Length = 327 Score = 35.4 bits (80), Expect = 0.058, Method: Compositional matrix adjust. Identities = 80/345 (23%), Positives = 126/345 (36%), Gaps = 87/345 (25%) Query: 15 RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWY 74 R K YD ++IG G G+ +A A KTLL+E GG N + Sbjct: 16 RGSHMTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGGQMNNTAEI------- 68 Query: 75 ASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134 +N P + T PE K + LE V+ Sbjct: 69 -----------------ENYP---GYETIMGPELSMK-----------MAEPLEGLGVEN 97 Query: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE---------LGT 185 +G+ +D + + +K + + I++ATG E IPG E Sbjct: 98 AYGFVTGIED-HGDYKKIITEDDEFITKSIIIATGANHRKLE-IPGEEEYGARGVSYCAV 155 Query: 186 DSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLV-----IRGETVL--RKFDE 238 FFR +E ++V+G G +E A G ++ +R + ++ R F E Sbjct: 156 CDGAFFRNQE----ILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLRAQEIIQQRAFKE 211 Query: 239 CIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLK--------IHMNDSKSIDDVDELI 290 N I D E K + V V KNV+T ++ I++ +D V E + Sbjct: 212 EKINFIWDSVPMEIKGDDKKIQSV-VYKNVKTGEVTEKAFGGIFIYVG----LDPVAEFV 266 Query: 291 WTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV 335 +G G II D++ TN+P I+++GDV Sbjct: 267 SDLGITDEAGW--------------IITDDHMRTNIPGIFAVGDV 297 >1ZOV-A nrPDB Length = 386 Score = 33.9 bits (76), Expect = 0.18, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 23/34 (67%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 + H+D +V+G GS G+A+ A G KTLLV++ Sbjct: 1 STHFDVIVVGAGSMGMAAGYYLAKQGVKTLLVDS 34 >4YNU-A nrPDB Length = 571 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 30/135 (22%) Query: 20 NTKHYDYLVIGGGSGGVASARR-AASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 NT YDY+V+GGG+ G+ A R + + LL+EA G + N Sbjct: 2 NTTTYDYIVVGGGTSGLVVANRLSENPDVSVLLLEA---GASVFN--------------- 43 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAY--------VHRLNGIYQKNLEKE 130 V++AN YGL +D ++ + N K+ +NG+ E Sbjct: 44 NPDVTNANGYGLAFGSAIDWQYQSINQSYAGGKQQVLRAGKALGGTSTINGMAYTRAEDV 103 Query: 131 KVDVVFGWARFNKDG 145 ++DV W + +G Sbjct: 104 QIDV---WQKLGNEG 115 >3FG2-P nrPDB Length = 404 Score = 33.1 bits (74), Expect = 0.26, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 8/139 (5%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDHYVKEGINVH 256 K VVV+GAG+IG+E A G E +V V+ R I + D + GI +H Sbjct: 143 KHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVTPEISSYFHDRHSGAGIRMH 202 Query: 257 KLSKIVKVEKNVETDKLK-IHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQ 315 + E E D++ + ++D ++ D ++ +G ++ + + Sbjct: 203 Y--GVRATEIAAEGDRVTGVVLSDGNTL-PCDLVVVGVGVIPNVEIAAAAGLPTAAG--- 256 Query: 316 IIADEYQNTNVPNIYSLGD 334 II D+ T+ P+I ++GD Sbjct: 257 IIVDQQLLTSDPHISAIGD 275 >4ZN0-A nrPDB Length = 311 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGG 59 YD ++IGGG G+ + A YG TL++E + G Sbjct: 8 YDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISG 43 >5KVH-A nrPDB Length = 543 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 81/376 (21%), Positives = 148/376 (39%), Gaps = 69/376 (18%) Query: 23 HYDYLVIGGGSGGVASAR--RAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD--- 77 H +L+IGGG+ A+AR RA GA+ L+V + K +W++ D Sbjct: 55 HVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDP---ELPYMRPPLSKELWFSDDPNV 111 Query: 78 ---LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134 L + ++ E +Y F P F H NG Sbjct: 112 TKTLRFKQANGKERSIY-----------FQPPSFYVSAQDLPHIENG------------- 147 Query: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHI-----LVATGG--KAIFPENIPGFELGTDS 187 G A V++ RDN ++ + I L+ATGG +++ + G E+ + + Sbjct: 148 --GVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRT 205 Query: 188 DGF-----FR----LEEQPKKVVVVGAGYIGIELAGVF----HGLGSET-HLVIRGETVL 233 F FR + + K + ++G G++G ELA LG+E L + Sbjct: 206 TLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMG 265 Query: 234 RKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTI 293 + E + N + +EG+ V + + V V + KL I + D + + + D ++ + Sbjct: 266 KILPEYLSNWTMEKVRREGVKVMPNAIVQSV--GVSSGKLLIKLKDGRKV-ETDHIVAAV 322 Query: 294 GRKSH--------LGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVA 345 G + + L + S+ G ++N+ Q ++ + + Y + +VE A Sbjct: 323 GLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHA 382 Query: 346 IAAGRKLSNRLFGPEK 361 + +GR + G K Sbjct: 383 VVSGRLAGENMTGAAK 398 >4MO2-B nrPDB Length = 368 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTC 61 YDYL++G G G A A G L+VE + +GG C Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNC 40 >2BXR-A nrPDB Length = 527 Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 22/32 (68%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 +D +VIGGG G+++A+ YG L++EA+ Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEAR 45 >6CR0-A nrPDB Length = 440 Score = 32.7 bits (73), Expect = 0.36, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 1/39 (2%) Query: 22 KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGG 59 K YD +V+G G G+ +AR ++ G L++EA+ LGG Sbjct: 7 KIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGG 45 >4XRR-A nrPDB Length = 456 Score = 32.7 bits (73), Expect = 0.37, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 18/29 (62%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSE 222 E P KVV+ GAGY+G LA G G+E Sbjct: 12 EPSPLKVVIAGAGYVGTCLAVTLAGRGAE 40 >5JFC-L nrPDB Length = 474 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 11/99 (11%) Query: 266 KNVETDKLKIHMNDSKS-----------IDDVDELIWTIGRKSHLGMGSENVGIKLNSHD 314 K +E +K+K+ D I + D I IG+ + G+K++ Sbjct: 365 KAIELEKMKLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQTPNKTFLETVPGLKVDEWG 424 Query: 315 QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLS 353 +I+ DE T++P +++ GD + +A+ GRK + Sbjct: 425 RIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAA 463 >3ATQ-A nrPDB Length = 453 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 22/32 (68%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 YD L+IGGG G ++A + + G K LLV++K Sbjct: 7 YDVLIIGGGFAGSSAAYQLSRRGLKILLVDSK 38 >2VVL-G nrPDB Length = 495 Score = 32.3 bits (72), Expect = 0.44, Method: Compositional matrix adjust. Identities = 15/32 (46%), Positives = 21/32 (65%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 +D +VIGGG G+ + R G KTLL+EA+ Sbjct: 40 WDVIVIGGGYCGLTATRDLTVAGFKTLLLEAR 71 >2VHY-A nrPDB Length = 377 Score = 32.3 bits (72), Expect = 0.44, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 14/77 (18%) Query: 161 ANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLG 220 A H++ GG+ + +PG E P VVV+GAG G A + +G+G Sbjct: 146 AYHLMRTQGGRGVLMGGVPGVE--------------PADVVVIGAGTAGYNAARIANGMG 191 Query: 221 SETHLVIRGETVLRKFD 237 + ++ LR+ D Sbjct: 192 ATVTVLDINIDKLRQLD 208 >5HIW-A nrPDB Length = 398 Score = 32.3 bits (72), Expect = 0.53, Method: Compositional matrix adjust. Identities = 16/61 (26%), Positives = 31/61 (50%) Query: 405 NSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKAD 464 +++ ++ A+LS + +RY+ P + V +V AE+ F +++ MG T A Sbjct: 80 HTRMRRLFNAVLSPRVISRYEEATVTPVARRVVERLVRKERAELFDDFAISMPMGVTSAL 139 Query: 465 F 465 F Sbjct: 140 F 140 >3NK2-X nrPDB Length = 431 Score = 32.0 bits (71), Expect = 0.66, Method: Compositional matrix adjust. Identities = 17/37 (45%), Positives = 24/37 (64%), Gaps = 1/37 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 YD +V+GGG G+ +AR + G K LL+E + LGG Sbjct: 2 YDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGG 38 >3IH9-A nrPDB Length = 456 Score = 32.0 bits (71), Expect = 0.66, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 401 IKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAE 447 + N TA Y +L+E P R+ I A P + LH GD+ E Sbjct: 16 LGAVNPGETAQYIPVLAEADPDRFGIALATPTGR---LHCAGDADVE 59 >6ACQ-A nrPDB Length = 302 Score = 32.0 bits (71), Expect = 0.67, Method: Compositional matrix adjust. Identities = 30/89 (33%), Positives = 41/89 (46%), Gaps = 18/89 (20%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV-- 255 KKV V+GAG +G +A F G E VLR I D +V G++ Sbjct: 22 KKVCVIGAGTMGSGIAQAFAAKGF--------EVVLRD--------IKDEFVDRGLDFIN 65 Query: 256 HKLSKIVKVEKNVETDKLKIHMNDSKSID 284 LSK+VK K E K++I S ++D Sbjct: 66 KNLSKLVKKGKIEEATKVEILTRISGTVD 94 >5USX-A nrPDB Length = 319 Score = 31.6 bits (70), Expect = 0.72, Method: Compositional matrix adjust. Identities = 59/267 (22%), Positives = 100/267 (37%), Gaps = 55/267 (20%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 ++ KH L++G G G +A AA +L+ GG V Sbjct: 2 SDMKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQGGQLTTTTEV----------- 50 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV-FG 137 +N P D E LT P + + R ++ + + ++ V F Sbjct: 51 -------------ENWPGDPEGLT--GPGLMDRMKEHAER----FETEIIFDHINEVDFS 91 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIF-----PENIPG--FELGTDSDGF 190 F V K D + YS + ++++TG A + E G DGF Sbjct: 92 TRPF-------VLKGDAAS--YSCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGF 142 Query: 191 FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 F + +KV VVG G +E A + +E HL+ R ++ + ++ + N + D Sbjct: 143 FY---RNQKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDSF--RAEKILINRLMDKVQN 197 Query: 251 EGINVHK---LSKIVKVEKNVETDKLK 274 I +H L +++ E V +LK Sbjct: 198 GNIVLHTDRVLDEVLGDEMGVTGVRLK 224 >3Q9T-A nrPDB Length = 577 Score = 31.6 bits (70), Expect = 0.79, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 24/41 (58%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALG 58 +T+ H+D++++GGG+ G A R A T+L+ +G Sbjct: 1 ATDGSHFDFVIVGGGTAGNTVAGRLAENPNVTVLIVEAGIG 41 >5YGQ-A nrPDB Length = 342 Score = 31.6 bits (70), Expect = 0.82, Method: Compositional matrix adjust. Identities = 72/336 (21%), Positives = 130/336 (38%), Gaps = 51/336 (15%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGGTCVNVGCVPKKVMWYASD 77 T T D L++G G G+ + K LV+ +GG C + P+K ++ Sbjct: 2 TETIKTDVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAEL--YPEKPIYDIPG 59 Query: 78 LATRVSHANEYGLYQNL-PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 + H L + + P + TF+ E + N+EK Sbjct: 60 IPMVTGHGLTEALMEQIKPFNP---TFHLSEMVE---------------NVEKI------ 95 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPEN--IPGFEL--GTDSDGFFR 192 G+ + N +V+ ++VA GG + P+ +PG E GT R Sbjct: 96 --------GDPGFRVTTNAGKVFECTVLVVAAGGGSFLPKRPPVPGVEAYEGTSVHYAVR 147 Query: 193 LEE--QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 E + K +++VG G ++ + + LV R + R ++ V Sbjct: 148 KMEDFRGKDILIVGGGDSALDWTLNLNPIAKSMTLVHRRDD-FRGAPHSVEQM--RQLVA 204 Query: 251 EGINVHKLSKIVKVE-KNVETDKLKIHMND-SKSIDDVDELIWTIGRKSHLGMGSENVGI 308 G K+ +I +++ N + + +ND + S D ++ G LG N G+ Sbjct: 205 SGKLDLKIGQITELQGDNGQLTGATVKLNDNTTSQIKCDAMLPFFGLTMKLG-PVANWGL 263 Query: 309 KLNSHDQIIADEYQNTNVPNIYSLGDV---VGKVEL 341 L ++ + TNVP I+++GD+ GK++L Sbjct: 264 DLENNLIPVDTGTFETNVPGIFAIGDINTYPGKLKL 299 >5VJ7-A nrPDB Length = 476 Score = 31.6 bits (70), Expect = 0.86, Method: Compositional matrix adjust. Identities = 22/97 (22%), Positives = 44/97 (45%) Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQI 316 K K+ +E+ K KI + D +I IG+ + + +K++ +I Sbjct: 368 KFEKMKPLEERDSRGKRKIVGTGEYITVEADTVIIAIGQTPNKVLWRATPELKVDEWGRI 427 Query: 317 IADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLS 353 + DE T++P +++ GD + +A+ GRK + Sbjct: 428 VVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAA 464 >4Y0E-A nrPDB Length = 338 Score = 31.2 bits (69), Expect = 0.93, Method: Compositional matrix adjust. Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 1/37 (2%) Query: 9 FRSLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASY 45 RSL +T+T YDY G SGGV++ RRAA Y Sbjct: 168 LRSLVDDLWATHTNLYDY-ASSGASGGVSAERRAAYY 203 >5MAC-A nrPDB Length = 474 Score = 31.2 bits (69), Expect = 0.99, Method: Compositional matrix adjust. Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 1/36 (2%) Query: 114 AYVHRLNG-IYQKNLEKEKVDVVFGWARFNKDGNVE 148 A+ +N +YQ +LE+E V + + W F++ GNV+ Sbjct: 71 AFSRTMNARVYQLDLERELVWIAYPWRLFDRGGNVQ 106 >5BR7-A nrPDB Length = 393 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 18/40 (45%), Positives = 25/40 (62%), Gaps = 2/40 (5%) Query: 24 YDYLVIGGGSGGVASARRAAS-YGAKTLLVEAKA-LGGTC 61 +D +V+G G G+ A RAAS G K L+VE ++ LGG Sbjct: 4 FDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNA 43 >1O5W-A nrPDB Length = 534 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 22/32 (68%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 +D +VIGGG G+A+A+ + Y L++EA+ Sbjct: 22 FDVVVIGGGISGLAAAKLLSEYKINVLVLEAR 53 >3F8P-A nrPDB Length = 323 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 37/142 (26%), Positives = 68/142 (47%), Gaps = 18/142 (12%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRK--FDECIQNT-----ITDHYVKEG 252 V V+G G +E A + ++ +L+ R +T + + E ++ + + VKE Sbjct: 157 VAVIGGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPIYVETVKKKPNVEFVLNSVVKE- 215 Query: 253 INVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNS 312 I K+ K V VE N++T ++K +N V+ + IG N GI+ ++ Sbjct: 216 IKGDKVVKQVVVE-NLKTGEIK-ELN-------VNGVFIEIGFDPPTDFAKSN-GIETDT 265 Query: 313 HDQIIADEYQNTNVPNIYSLGD 334 + I DE+ T+VP +++ GD Sbjct: 266 NGYIKVDEWMRTSVPGVFAAGD 287 >3ABT-A nrPDB Length = 662 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 20/29 (68%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEAK 55 ++IG G G+A+AR+ S+G L+EA+ Sbjct: 111 IIIGSGVSGLAAARQLQSFGMDVTLLEAR 139 >2Q7V-A nrPDB Length = 325 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 77/334 (23%), Positives = 126/334 (37%), Gaps = 64/334 (19%) Query: 17 MSTNTKH-YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYA 75 M+ T H YD ++IGGG G+ +A TL++E GG ++ W Sbjct: 1 MTAPTAHDYDVVIIGGGPAGLTAAIYTGRAQLSTLILEKGMPGG----------QIAWSE 50 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV 135 +N P +PE + R++ +K K ++D V Sbjct: 51 E--------------VENFP--------GFPEPIAGME-LAQRMHQQAEKFGAKVEMDEV 87 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGG---KAIFP--ENIPGFELGT--DSD 188 G R E Y A +++ATG K P +N G + T D Sbjct: 88 QGVQHDATSHPYPFTVRGYNGE-YRAKAVILATGADPRKLGIPGEDNFWGKGVSTCATCD 146 Query: 189 GFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV-------LRKFDECIQ 241 GFF + KKVVV+G G +E E ++ R +T+ R F Sbjct: 147 GFFY---KGKKVVVIGGGDAAVEEGMFLTKFADEVTVIHRRDTLRANKVAQARAFANPKM 203 Query: 242 NTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGM 301 I D V+E +S VK+ +N++T ++ D I IG + Sbjct: 204 KFIWDTAVEEIQGADSVSG-VKL-RNLKTGEVSELATDGVFI--------FIGHVPNTAF 253 Query: 302 GSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV 335 + V ++ + + + + Y TN+P +++ GDV Sbjct: 254 VKDTVSLRDDGYVDVRDEIY--TNIPMLFAAGDV 285 >5UTH-A nrPDB Length = 319 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 51/205 (24%), Positives = 78/205 (38%), Gaps = 50/205 (24%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYAS 76 MST+ +D ++IG G G +A AA K L+ E GG + V Sbjct: 9 MSTSQTVHDVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGGALMTTTEV--------- 59 Query: 77 DLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 +N P +E +T PE + R + +L E VD V Sbjct: 60 ---------------ENYPGFREGIT--GPELMDQMREQALR----FGADLRMEDVDAV- 97 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE----LGTDS----D 188 +G V+ + E + A +++A G A +PG E +G + D Sbjct: 98 -----QLEGPVKTVVVGD--ETHQARAVILAMGAAARHL-GVPGEEALTGMGVSTCATCD 149 Query: 189 GFFRLEEQPKKVVVVGAGYIGIELA 213 GFF + + +VVVG G +E A Sbjct: 150 GFFF---RDQDIVVVGGGDSAMEEA 171 >4KUG-A nrPDB Length = 290 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 18/89 (20%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN--V 255 KKV V+GAG +G + F G E I I + +V GI Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKGCEV----------------IVRDIKEEFVDRGIATIT 45 Query: 256 HKLSKIVKVEKNVETDKLKIHMNDSKSID 284 LSK+V EK E DK +I S + D Sbjct: 46 KSLSKLVAKEKITEADKEEILSRISGTTD 74 >5MOG-A nrPDB Length = 497 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%), Gaps = 1/47 (2%) Query: 14 IRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGG 59 R TK ++ G G G+++A+ A G K +L+EA+ LGG Sbjct: 8 FRNSEQPTKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGG 54 >1I8T-A nrPDB Length = 367 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 29/108 (26%), Positives = 41/108 (37%), Gaps = 28/108 (25%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGC--------------VP 68 YDY+++G G G A K L++E + +GG C Sbjct: 2 YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTN 61 Query: 69 KKVMW-YASDLATRVSHANEYGLYQNLPL----DKE-HLTFNWPEFKQ 110 K +W Y +DL E+ + N PL DK +L FN F Q Sbjct: 62 DKYIWDYVNDLV-------EFNRFTNSPLAIYKDKLFNLPFNMNTFHQ 102 >5U63-A nrPDB Length = 321 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 63/282 (22%), Positives = 102/282 (36%), Gaps = 86/282 (30%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 ++ KH L++G G G +A AA K +LV Sbjct: 5 SDIKHAKLLILGSGPAGYTAAIYAARANLKPVLVT------------------------- 39 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL---EKEKVDVV 135 GL Q L NWP D + +G+ Q+ L EK + ++V Sbjct: 40 ----------GLQQGGQLTTTDEIENWP-----GDFEMTTGSGLMQRMLQHAEKFETEIV 84 Query: 136 FGWARFNKDGNVEVQKRD----NTTEVYSANHILVATGGKAIF-----PENIPG--FELG 184 F + V++ R + ++ + +++ATG A + EN G Sbjct: 85 F-----DHINRVDLSSRPFKLFGDVQNFTCDALIIATGASARYIGLPSEENYKGRGVSAC 139 Query: 185 TDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 DGFF + K V V+G G +E A + S HL+ R Sbjct: 140 ATCDGFFY---RNKPVGVIGGGNTAVEEALYLANIASTVHLIHR---------------- 180 Query: 245 TDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDV 286 D + E I + +L K KVE+ KI ++ +++D+V Sbjct: 181 RDSFRAEKILIDRLYK--KVEEG------KIVLHTDRTLDEV 214 >5NCC-A nrPDB Length = 594 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 27/50 (54%) Query: 3 SATKQTFRSLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLV 52 SA + + L + + YDY+++GGG+ A R ++ G+K +LV Sbjct: 3 SAVEDIRKVLSDSSSPVAGQKYDYILVGGGTAACVLANRLSADGSKRVLV 52 >4A7P-A nrPDB Length = 446 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 23/104 (22%), Positives = 45/104 (43%), Gaps = 12/104 (11%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 ++ ++G GY+G+ F G H V+ + RK + QN + + + G++ Sbjct: 10 RIAMIGTGYVGLVSGACFSDFG---HEVVCVDKDARKIELLHQNVMPIY--EPGLDAL-- 62 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMG 302 V NV+ +L + ++ + D D + +G S G G Sbjct: 63 -----VASNVKAGRLSFTTDLAEGVKDADAVFIAVGTPSRRGDG 101 >5L3D-A nrPDB Length = 852 Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Query: 13 QIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 +I+ + T K ++IG G G+A+AR+ S+G L+EA+ Sbjct: 269 RIKPLPTK-KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEAR 310 >1AHW-A nrPDB Length = 214 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 402 KVYNSKFTAMYYAM-LSEKSPTRYKIVCAGPNEKVVGLHIVGDSSA--------EILQGF 452 K + S T +YYA L++ P+R+ +G + + + D +A E F Sbjct: 39 KPWKSPKTLIYYATSLADGVPSRFSGSGSGQDYSLTISSLESDDTATYYCLQHGESPYTF 98 Query: 453 GVAIKMGATKADFDNCVAIHPTSAEELVT 481 G K+ +AD V+I P S+E+L + Sbjct: 99 GGGTKLEINRADAAPTVSIFPPSSEQLTS 127 >3CR3-A nrPDB Length = 192 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 14/98 (14%) Query: 96 LDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNT 155 LD L + E QKR G Q EK VD+ W+ F D + +DN Sbjct: 98 LDTSELIYAGLEAIQKR--------GKAQVG-EKTMVDI---WSAFLNDLQTDSASKDNL 145 Query: 156 TEVYSANHILVATGGKAIF--PENIPGFELGTDSDGFF 191 +V A+ L+AT G+A + +I + GT S + Sbjct: 146 EKVVKASAGLLATKGRASYLGERSIGHIDPGTQSSAYL 183 >1E3W-A nrPDB Length = 261 Score = 29.3 bits (64), Expect = 4.4, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 28/53 (52%), Gaps = 10/53 (18%) Query: 20 NTKHYDYLVIGGGSG-GVASARRAASYGAKTLLV---------EAKALGGTCV 62 + K ++ GG SG G+++A+R GA +L+ EAK LGG C+ Sbjct: 7 SVKGLVAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCI 59 >1XTY-A nrPDB Length = 120 Score = 28.9 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 282 SIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII--ADEYQNTNVPNIYSLGDVVGKV 339 SI + + L W L G + +K+NS D+II A + + N+P +S+ + GK Sbjct: 33 SIINSNNLRWKEWLNEWLHQGQPKIIVKVNSLDEIISRAKKAETMNLP--FSIIEDAGKT 90 Query: 340 ELTPVAI 346 +L P I Sbjct: 91 QLEPGTI 97 >3BI4-A nrPDB Length = 516 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRG 229 KKV+++GAG G++ A H G + LV+ Sbjct: 9 KKVIIIGAGIAGLKAASTLHQNGIQDCLVLEA 40 >1REO-A nrPDB Length = 486 Score = 28.5 bits (62), Expect = 6.3, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLV 226 PK VVVVGAG G+ A V G G + ++ Sbjct: 33 PKHVVVVGAGMSGLSAAYVLSGAGHQVTVL 62 >3IHG-A nrPDB Length = 535 Score = 28.5 bits (62), Expect = 6.4, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 N D LV+G G GG+++A A G + L+VE + Sbjct: 2 NDHEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 >3K30-A nrPDB Length = 690 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 4/69 (5%) Query: 6 KQTFRSLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNV 64 ++ + +IR ++ + LV+G G G+ +AR G +L EA + LGG Sbjct: 377 RRGWHPERIRAKESDAR---VLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRVTQE 433 Query: 65 GCVPKKVMW 73 +P W Sbjct: 434 SALPGLSAW 442 >5EZ7-A nrPDB Length = 392 Score = 28.5 bits (62), Expect = 7.1, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKALGG 59 D L++GGG G+ R G T+LVE+ +LGG Sbjct: 9 DILIVGGGIAGLWLNARLRRAGYATVLVESASLGG 43 >3OZ2-A nrPDB Length = 397 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 32/80 (40%), Positives = 43/80 (53%), Gaps = 7/80 (8%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVG-CVPKKVMWYASDLATRV 82 YD LV+GGG GG +AR AA YG KTL++E + G+ V G + K ++ A A R Sbjct: 5 YDVLVVGGGPGGSTAARYAAKYGLKTLMIEKRPEIGSPVRCGEGLSKGILNEADIKADRS 64 Query: 83 SHANE------YGLYQNLPL 96 ANE YG + P+ Sbjct: 65 FIANEVKGARIYGPSEKRPI 84 >1F8S-A nrPDB Length = 498 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 18/30 (60%) Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLV 226 PK VV+VGAG G+ A V G G + ++ Sbjct: 33 PKHVVIVGAGMAGLSAAYVLAGAGHQVTVL 62 >4C3X-A nrPDB Length = 530 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 15/105 (14%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGGTCVNVGC---VPKKVM 72 M T D LV+G G G + A AA+ G T+++E GGT G +P + Sbjct: 21 MQDWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSGASIWLPGTQV 80 Query: 73 WYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVH 117 + L +A Y + L D E +++DAYV Sbjct: 81 QERAGLPDSTENARTY--LRALLGDAE---------SERQDAYVE 114 >3LLV-A nrPDB Length = 141 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE 53 T Y+Y+VIG + GV R + G K L V+ Sbjct: 2 TENGRYEYIVIGSEAAGVGLVRELTAAGKKVLAVD 36 >3KVE-A nrPDB Length = 486 Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust. Identities = 14/24 (58%), Positives = 15/24 (62%) Query: 197 PKKVVVVGAGYIGIELAGVFHGLG 220 PK VVVVGAG G+ A V G G Sbjct: 33 PKHVVVVGAGMSGLSAAYVLAGAG 56 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2HQM-A nrPDB 661 0.0 1GEU-A nrPDB 549 e-156 6N7F-A nrPDB 548 e-156 5VDN-A nrPDB 546 e-156 2R9Z-A nrPDB 532 e-152 5U1O-A nrPDB 529 e-150 2AAQ-A nrPDB 526 e-150 5V36-A nrPDB 523 e-149 6B4O-A nrPDB 520 e-148 1ZDL-A nrPDB 518 e-147 6DU7-A nrPDB 515 e-146 2X8H-A nrPDB 515 e-146 4LA1-A nrPDB 509 e-145 2WOV-A nrPDB 507 e-144 2YAU-A nrPDB 498 e-141 4KPR-E nrPDB 497 e-141 5U8W-A nrPDB 497 e-141 4NEW-A nrPDB 496 e-141 2CFY-A nrPDB 495 e-140 5TR3-A nrPDB 492 e-139 1FEC-A nrPDB 490 e-139 5W1J-A nrPDB 490 e-139 5J5Z-A nrPDB 484 e-137 2NVK-X nrPDB 483 e-137 3O0H-A nrPDB 482 e-136 3LAD-A nrPDB 481 e-136 3URH-A nrPDB 479 e-136 4B1B-A nrPDB 476 e-135 1DXL-A nrPDB 472 e-133 1EBD-A nrPDB 471 e-133 1ONF-A nrPDB 468 e-132 6BZ0-A nrPDB 467 e-132 1V59-A nrPDB 466 e-131 2YQU-A nrPDB 465 e-131 4DNA-A nrPDB 455 e-128 2QAE-A nrPDB 450 e-127 6AON-A nrPDB 450 e-127 2EQ6-A nrPDB 449 e-126 4JDR-A nrPDB 443 e-125 5X1Y-B nrPDB 440 e-124 6CMZ-A nrPDB 431 e-121 1LVL-A nrPDB 415 e-116 3II4-A nrPDB 409 e-114 4YWO-A nrPDB 385 e-107 1OJT-A nrPDB 380 e-106 5U25-A nrPDB 375 e-104 1ZK7-A nrPDB 352 2e-97 3IC9-A nrPDB 316 1e-86 1XDI-A nrPDB 311 6e-85 3L8K-A nrPDB 308 3e-84 3Q6J-A nrPDB 306 2e-83 3ICS-A nrPDB 197 8e-51 3IWA-A nrPDB 196 2e-50 2BC1-A nrPDB 187 1e-47 3CGD-A nrPDB 185 3e-47 5ER0-A nrPDB 185 5e-47 3NTA-A nrPDB 179 3e-45 3OC4-A nrPDB 175 5e-44 4FX9-A nrPDB 171 5e-43 1YQZ-A nrPDB 165 3e-41 2CDU-A nrPDB 161 8e-40 1Q1R-A nrPDB 147 9e-36 2YVG-A nrPDB 133 2e-31 3AB1-A nrPDB 128 7e-30 Sequences not found previously or not previously below threshold: 1NHQ-A nrPDB 164 9e-41 4GCM-A nrPDB 119 3e-27 5UWY-A nrPDB 119 3e-27 3LXD-A nrPDB 117 1e-26 3FG2-P nrPDB 117 1e-26 5MJK-A nrPDB 114 9e-26 5JCN-A nrPDB 111 5e-25 5UTH-A nrPDB 110 1e-24 2A87-A nrPDB 109 2e-24 1XHC-A nrPDB 108 5e-24 4ZN0-A nrPDB 108 5e-24 2Q7V-A nrPDB 107 1e-23 3F8P-A nrPDB 105 3e-23 2V3B-A nrPDB 104 1e-22 6BWT-A nrPDB 104 1e-22 5U63-A nrPDB 102 3e-22 5JFC-L nrPDB 102 4e-22 1F6M-A nrPDB 102 4e-22 4YRY-B nrPDB 99 2e-21 2ZBW-A nrPDB 98 6e-21 5VJ7-A nrPDB 98 7e-21 5USX-A nrPDB 97 2e-20 4EMJ-A nrPDB 95 5e-20 3LZX-A nrPDB 91 1e-18 5W4C-A nrPDB 91 1e-18 4CBQ-A nrPDB 90 3e-18 5YGQ-A nrPDB 88 7e-18 5KVH-A nrPDB 86 2e-17 3ISH-A nrPDB 86 4e-17 4YKF-A nrPDB 84 2e-16 6GAS-A nrPDB 84 2e-16 5XHU-A nrPDB 83 3e-16 3R9U-A nrPDB 83 3e-16 6BPY-A nrPDB 82 4e-16 3D8X-A nrPDB 81 1e-15 1FL2-A nrPDB 80 2e-15 6GAR-A nrPDB 80 3e-15 5MIU-A nrPDB 79 4e-15 2VDC-G nrPDB 79 5e-15 3KLJ-A nrPDB 78 6e-15 4JNQ-A nrPDB 74 1e-13 1VDC-A nrPDB 74 2e-13 5TWC-A nrPDB 70 2e-12 5M5J-A nrPDB 67 2e-11 4G74-A nrPDB 66 3e-11 5JWC-A nrPDB 65 7e-11 4NTC-A nrPDB 62 4e-10 5NA1-A nrPDB 62 5e-10 2CVJ-A nrPDB 60 2e-09 2WHD-A nrPDB 60 3e-09 4FK1-A nrPDB 59 4e-09 1Y56-A nrPDB 56 5e-08 5NMX-A nrPDB 55 9e-08 4OVI-A nrPDB 54 2e-07 3UP5-A nrPDB 52 5e-07 1NAA-A nrPDB 51 2e-06 3H8L-A nrPDB 50 3e-06 4USR-A nrPDB 49 4e-06 4C5O-A nrPDB 49 4e-06 1PS9-A nrPDB 49 5e-06 6ER9-A nrPDB 47 2e-05 2TMD-A nrPDB 47 2e-05 4TLZ-A nrPDB 46 3e-05 2VOU-A nrPDB 46 4e-05 6A37-A nrPDB 46 4e-05 4B68-A nrPDB 46 5e-05 4RG3-A nrPDB 45 6e-05 6JDK-A nrPDB 45 6e-05 3KVE-A nrPDB 45 8e-05 3NIX-A nrPDB 45 8e-05 5BR7-A nrPDB 45 8e-05 6CR0-A nrPDB 44 9e-05 1REO-A nrPDB 44 9e-05 1F8S-A nrPDB 44 1e-04 5J7X-A nrPDB 44 1e-04 3BHF-A nrPDB 44 1e-04 3K30-A nrPDB 44 2e-04 1ZOV-A nrPDB 44 2e-04 3RHA-A nrPDB 43 2e-04 2BXR-A nrPDB 43 3e-04 3MJ4-A nrPDB 43 4e-04 1O5W-A nrPDB 43 4e-04 3T14-A nrPDB 41 0.001 2ZXH-A nrPDB 41 0.001 1I8T-A nrPDB 41 0.001 4Y4M-A nrPDB 41 0.002 4TXK-A nrPDB 41 0.002 2BRY-A nrPDB 41 0.002 5EQD-A nrPDB 40 0.002 2GMH-A nrPDB 40 0.002 5AYV-A nrPDB 40 0.002 1QO8-A nrPDB 40 0.003 4AP1-A nrPDB 40 0.003 4A7P-A nrPDB 39 0.003 3ATQ-A nrPDB 39 0.003 2JB2-A nrPDB 39 0.004 3NK2-X nrPDB 39 0.004 4Z2R-A nrPDB 39 0.004 2VHY-A nrPDB 39 0.005 3HYW-A nrPDB 39 0.006 3HDH-A nrPDB 39 0.006 4Y4N-A nrPDB 38 0.007 3ABT-A nrPDB 38 0.007 5KXJ-A nrPDB 38 0.007 5L3D-A nrPDB 38 0.008 6C6P-A nrPDB 38 0.010 2UZZ-A nrPDB 38 0.010 1C0L-A nrPDB 38 0.010 1F14-A nrPDB 38 0.011 6BRD-A nrPDB 38 0.011 4A6N-B nrPDB 38 0.011 3GG2-A nrPDB 38 0.013 4C3X-A nrPDB 38 0.014 6HRD-A nrPDB 37 0.016 2YFH-A nrPDB 37 0.017 3IHG-A nrPDB 37 0.018 3WE0-A nrPDB 37 0.019 2VVL-G nrPDB 37 0.024 3HWR-A nrPDB 36 0.025 1KNR-A nrPDB 36 0.027 6ACQ-A nrPDB 36 0.036 4MO2-B nrPDB 36 0.050 2GAG-B nrPDB 36 0.050 1SEZ-A nrPDB 36 0.050 4MOP-A nrPDB 36 0.053 4DGK-A nrPDB 35 0.061 4YNU-A nrPDB 35 0.063 5L46-A nrPDB 35 0.068 5EB4-A nrPDB 35 0.076 3KYB-A nrPDB 35 0.077 6H3G-A nrPDB 35 0.082 5XGV-A nrPDB 35 0.082 3Q9T-A nrPDB 35 0.090 3UKH-A nrPDB 35 0.090 5EZ7-A nrPDB 34 0.097 4FHN-X nrPDB 34 0.097 4P9S-A nrPDB 34 0.11 6DLL-A nrPDB 34 0.12 2E5V-A nrPDB 34 0.12 3CP8-A nrPDB 34 0.13 4K2X-A nrPDB 34 0.14 1X14-A nrPDB 34 0.14 4H7U-A nrPDB 34 0.16 5I68-A nrPDB 34 0.16 3S61-A nrPDB 34 0.16 2Y0D-A nrPDB 34 0.19 4RPJ-A nrPDB 34 0.19 3COX-A nrPDB 34 0.19 4B4O-A nrPDB 34 0.20 5MOG-A nrPDB 33 0.21 3HN2-A nrPDB 33 0.22 4IIN-A nrPDB 33 0.23 1FOH-A nrPDB 33 0.24 5KOX-A nrPDB 33 0.24 3G5Q-A nrPDB 33 0.28 1DOD-A nrPDB 33 0.29 4XRR-A nrPDB 33 0.30 5PGZ-A nrPDB 33 0.31 4N9X-A nrPDB 33 0.36 2XVH-A nrPDB 33 0.36 1E3J-A nrPDB 33 0.40 3WSV-A nrPDB 33 0.43 4KUG-A nrPDB 33 0.44 4CPD-A nrPDB 32 0.46 1GPE-A nrPDB 32 0.47 4UDQ-A nrPDB 32 0.48 4U2L-A nrPDB 32 0.48 4L68-A nrPDB 32 0.53 6J0Z-C nrPDB 32 0.56 5NCC-A nrPDB 32 0.57 3BI4-A nrPDB 32 0.57 5XMJ-A nrPDB 32 0.58 2Y08-A nrPDB 32 0.59 1LQU-A nrPDB 32 0.60 3LLV-A nrPDB 32 0.61 3GDN-A nrPDB 32 0.64 5TUF-A nrPDB 32 0.65 3V8E-A nrPDB 32 0.65 4IV9-A nrPDB 32 0.74 3P7M-A nrPDB 32 0.78 1RP0-A nrPDB 31 0.79 3RED-A nrPDB 31 0.82 3IHM-A nrPDB 31 0.85 5WIT-1k nrPDB 31 0.85 2CDC-A nrPDB 31 0.93 2GAG-A nrPDB 31 0.97 4NEG-A nrPDB 31 0.98 3RIM-A nrPDB 31 1.1 3G05-A nrPDB 31 1.1 2EEZ-A nrPDB 31 1.1 4R16-A nrPDB 31 1.2 3F3S-A nrPDB 31 1.2 3CP2-A nrPDB 31 1.2 3DWF-A nrPDB 31 1.2 3OJO-A nrPDB 31 1.4 2IVE-A nrPDB 31 1.4 4V8P-BH nrPDB 31 1.4 3OZ2-A nrPDB 31 1.5 2QA2-A nrPDB 31 1.5 3K6J-A nrPDB 31 1.5 4G65-A nrPDB 31 1.6 2BS2-A nrPDB 31 1.6 6MO6-A nrPDB 31 1.7 3HG7-A nrPDB 31 1.7 2WTB-A nrPDB 31 1.7 4PRK-A nrPDB 30 1.8 4K22-A nrPDB 30 1.9 4D3F-A nrPDB 30 2.2 3KKJ-A nrPDB 30 2.2 1B04-A nrPDB 30 2.2 1VM7-A nrPDB 30 2.2 6D9T-A nrPDB 30 2.5 4ZCC-A nrPDB 30 2.5 3SM8-A nrPDB 30 2.7 3RP7-A nrPDB 30 2.8 3I83-A nrPDB 30 2.8 4Z8X-A nrPDB 30 2.9 3L6D-A nrPDB 30 3.0 3FPZ-A nrPDB 29 3.1 5TUM-A nrPDB 29 3.1 1MV8-A nrPDB 29 3.2 4HA6-A nrPDB 29 3.2 1VRQ-A nrPDB 29 3.2 3LOV-A nrPDB 29 3.3 4Z44-A nrPDB 29 3.3 1H5Y-A nrPDB 29 3.3 4JA9-A nrPDB 29 3.4 1QU3-A nrPDB 29 3.6 2DI4-A nrPDB 29 3.9 6F73-A nrPDB 29 3.9 1A17-A nrPDB 29 3.9 3TR4-A nrPDB 29 4.0 4Y0E-A nrPDB 29 4.3 4X4J-A nrPDB 29 4.4 4GL2-A nrPDB 29 4.4 3B6E-A nrPDB 29 4.4 1PJ5-A nrPDB 29 4.4 3CUK-A nrPDB 29 4.4 1VE9-A nrPDB 29 4.4 1XFD-A nrPDB 29 4.5 3K8D-A nrPDB 29 5.0 3X2F-A nrPDB 29 5.5 2EW2-A nrPDB 29 5.6 5Y77-A nrPDB 29 5.7 6OKK-C nrPDB 29 5.9 3JBO-C nrPDB 29 5.9 1UIR-A nrPDB 29 6.1 4EIQ-A nrPDB 29 6.2 5ZYN-B nrPDB 29 6.5 2B76-A nrPDB 28 6.7 3F52-A nrPDB 28 7.2 3MOG-A nrPDB 28 7.2 4M1Q-A nrPDB 28 7.3 2RGJ-A nrPDB 28 7.4 2A9F-A nrPDB 28 7.6 2ZJ1-A nrPDB 28 7.7 2YQ5-A nrPDB 28 7.8 3JSK-A nrPDB 28 7.8 3I6D-A nrPDB 28 7.9 2QK4-A nrPDB 28 8.6 1QP8-A nrPDB 28 8.9 5Z23-C nrPDB 28 9.0 2CUL-A nrPDB 28 9.0 >2HQM-A nrPDB Length = 479 Score = 661 bits (1707), Expect = 0.0, Method: Composition-based stats. Identities = 467/470 (99%), Positives = 468/470 (99%) Query: 14 IRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMW 73 + MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMW Sbjct: 2 VEFMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMW 61 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD Sbjct: 62 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 121 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL 193 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL Sbjct: 122 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL 181 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI Sbjct: 182 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 241 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH Sbjct: 242 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 301 Query: 314 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP 373 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP Sbjct: 302 DQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVP 361 Query: 374 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 433 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE Sbjct: 362 SVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 421 Query: 434 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR Sbjct: 422 KVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 471 >1GEU-A nrPDB Length = 450 Score = 549 bits (1415), Expect = e-156, Method: Composition-based stats. Identities = 230/466 (49%), Positives = 302/466 (64%), Gaps = 18/466 (3%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 TKHYDY+ IGGGSGG+AS RAA YG K L+EAK LGGTCVNVGCVPKKVMW+A+ + Sbjct: 1 MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIR 60 Query: 80 TRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + + +YG D FNW R AY+ R++ Y+ L K VDV+ G+ Sbjct: 61 EAIHMYGPDYGF------DTTINKFNWETLIASRTAYIDRIHTSYENVLGKNNVDVIKGF 114 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK 198 ARF +EV E +A+HIL+ATGG+ P +IPG E G DSDGFF L P+ Sbjct: 115 ARFVDAKTLEVNG-----ETITADHILIATGGRPSHP-DIPGVEYGIDSDGFFALPALPE 168 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 +V VVGAGYIG+EL GV +GLG++THL + L FD I T+ + EG +H Sbjct: 169 RVAVVGAGYIGVELGGVINGLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEGPQLHTN 228 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS-HLGMGSENVGIKLNSHDQII 317 + V KN + L + + D +S + VD LIW IGR+ + + E G+K N I+ Sbjct: 229 AIPKAVVKNTDGS-LTLELEDGRS-ETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIV 286 Query: 318 ADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 D+YQNTN+ IY++GD G VELTPVA+AAGR+LS RLF + ++ LDY N+P+V+F Sbjct: 287 VDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKP--DEHLDYSNIPTVVF 344 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVG 437 SHP G++G++E +A E+YG + +KVY S FTAMY A+ + + P R K+VC G EK+VG Sbjct: 345 SHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGSEEKIVG 404 Query: 438 LHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 +H +G E+LQGF VA+KMGATK DFDN VAIHPT+AEE VTMR Sbjct: 405 IHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR 450 >6N7F-A nrPDB Length = 453 Score = 548 bits (1413), Expect = e-156, Method: Composition-based stats. Identities = 225/462 (48%), Positives = 313/462 (67%), Gaps = 18/462 (3%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV- 82 YDY+VIGGGS G+ASA RAA +GAK LL E K +GGTCVN+GCVPKKVMWY + +A + Sbjct: 8 YDYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILG 67 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 ++A +YG D + F++ + K R AY+ R++ Y++ E+ VD ++ +A F Sbjct: 68 TYAKDYGF------DFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFK 121 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVV 202 VE+ ++Y+A HIL+ATGG +FP +I G + G SDGFF L+E PK+ V Sbjct: 122 DAHTVEIAG-----QLYTAPHILIATGGHPVFP-DIEGAQYGISSDGFFALDEVPKRTAV 175 Query: 203 VGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIV 262 VGAGYI +ELAGV H LGS+T L IR + LR FD+ I + + D G +H +++ Sbjct: 176 VGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVA 235 Query: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEY 321 KV KN + + L +++ D + + +VD+LIW IGRK +L G + G+ LN I D Y Sbjct: 236 KVVKNTD-ESLTLYLKDGQEV-EVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIETDAY 293 Query: 322 QNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPE 381 +NT+V IY++GDV GK+ LTPVA+AAGR+LS RLF + ++KLDY+NV +VIFSHP Sbjct: 294 ENTSVKGIYAVGDVNGKLALTPVAVAAGRRLSERLFNGKT--DEKLDYQNVATVIFSHPV 351 Query: 382 AGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIV 441 GS+G+SE+ A+++YG+E +K Y S+FT+M+ A+ + + P K+V G EK+VGLH + Sbjct: 352 IGSVGLSEEAAVKQYGQEAVKTYQSRFTSMFTAITNHRQPCLMKLVTVGDTEKIVGLHGI 411 Query: 442 GDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 G E++QGF VAIKMGATKADFDN VAIHPT +EE VTMR Sbjct: 412 GYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 453 >5VDN-A nrPDB Length = 463 Score = 546 bits (1408), Expect = e-156, Method: Composition-based stats. Identities = 236/466 (50%), Positives = 303/466 (65%), Gaps = 18/466 (3%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 TKHYDYL IGGGSGG+AS RAA YG K L+EAK LGGTCVNVGCVPKKVMW+A+ +A Sbjct: 14 MTKHYDYLAIGGGSGGIASINRAAMYGKKCALIEAKQLGGTCVNVGCVPKKVMWHAAQIA 73 Query: 80 TRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + + +YG D F+W + R AY+ R++ Y++ L KVDV+ G+ Sbjct: 74 EAIHLYGPDYGF------DTTVNHFDWKKLIANRTAYIDRIHQSYERGLGNNKVDVIQGF 127 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK 198 ARF VEV E +A+HIL+ATGG+ P +IPG E G DSDGFF L+E PK Sbjct: 128 ARFVDAHTVEVNG-----ETITADHILIATGGRPSHP-DIPGAEYGIDSDGFFELDEMPK 181 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 +V VVGAGYI +E+AGV +GLG+ETHL +R LR FD I T+ + EG +H Sbjct: 182 RVAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLHTE 241 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQII 317 S V KN + L + + + + VD LIW IGR+ + G+K N I Sbjct: 242 SVPKAVIKNADGS-LTLQLENGTEV-TVDHLIWAIGREPATDNLNLSVTGVKTNDKGYIE 299 Query: 318 ADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 D++QNTNV IY++GD G VELTPVA+AAGR+LS RLF + ++ LDY N+P+V+F Sbjct: 300 VDKFQNTNVKGIYAVGDNTGVVELTPVAVAAGRRLSERLFNNKP--DEHLDYSNIPTVVF 357 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVG 437 SHP G+IG++E +A EK+G + +KVY S FTAMY A+ + P R K+VC G EK+VG Sbjct: 358 SHPPIGTIGLTEPQAREKFGDDQVKVYTSSFTAMYSAVTQHRQPCRMKLVCVGAEEKIVG 417 Query: 438 LHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 +H +G EILQGF VA+KMGATK DFDN VAIHPT+AEE VTMR Sbjct: 418 IHGIGFGMDEILQGFAVAMKMGATKKDFDNTVAIHPTAAEEFVTMR 463 >2R9Z-A nrPDB Length = 463 Score = 532 bits (1372), Expect = e-152, Method: Composition-based stats. Identities = 213/465 (45%), Positives = 302/465 (64%), Gaps = 18/465 (3%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 T+H+D + IGGGSGG+A A +AA++G + L+E+KALGGTCVNVGCVPKKVMWYAS LA Sbjct: 1 MTQHFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKALGGTCVNVGCVPKKVMWYASHLA 60 Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA 139 V A +G+ T +WP RD Y+ +N + +E+ + V G A Sbjct: 61 EAVRDAPGFGVQA------SGGTLDWPRLVAGRDRYIGAINSFWDGYVERLGITRVDGHA 114 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKK 199 RF +EV+ + SA+HI++ATGG+ I P +PG ELG SDGFF L++QPK+ Sbjct: 115 RFVDAHTIEVEG-----QRLSADHIVIATGGRPIVP-RLPGAELGITSDGFFALQQQPKR 168 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V ++GAGYIGIELAG+ GSE +V + +L +FD + T+ ++ +GI H Sbjct: 169 VAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHLEF 228 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIA 318 + +E++ + + D ++ D +IW +GR + +G E GI++ S+ + Sbjct: 229 AVAALERDAQGT--TLVAQDGTRLEGFDSVIWAVGRAPNTRDLGLEAAGIEVQSNGMVPT 286 Query: 319 DEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFS 378 D YQNTNVP +Y+LGD+ G+ +LTPVAIAAGR+L+ RLF + R KLDY+N+P+V+F+ Sbjct: 287 DAYQNTNVPGVYALGDITGRDQLTPVAIAAGRRLAERLFDGQSER--KLDYDNIPTVVFA 344 Query: 379 HPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 HP +G+SE EA E+ G + + VY + FT M YA+ T K+VCAGP ++VVG+ Sbjct: 345 HPPLSKVGLSEPEARERLG-DVLTVYETSFTPMRYALNEHGPKTAMKLVCAGPEQRVVGV 403 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 H++GD + E+LQGF VA+KMGATKADFDN VAIHP SAEELVT++ Sbjct: 404 HVIGDGADEMLQGFAVAVKMGATKADFDNTVAIHPGSAEELVTLK 448 >5U1O-A nrPDB Length = 458 Score = 529 bits (1362), Expect = e-150, Method: Composition-based stats. Identities = 238/472 (50%), Positives = 318/472 (67%), Gaps = 22/472 (4%) Query: 15 RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWY 74 + M+T H+DY+ IGGGSGG+ASA RAA YGAK L+EA+ LGGTCVNVGCVPKKVMW+ Sbjct: 6 KVMAT---HFDYICIGGGSGGIASANRAAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWH 62 Query: 75 ASDLATRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 + +A ++ +A +YG D + F+W + + R AY+ R++ Y + L KV+ Sbjct: 63 GAQIAEAMNLYAEDYGF------DVDVKGFDWSKLVESRQAYIGRIHQSYDRVLGNNKVN 116 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRL 193 V+ G+A+F + VEV E Y+A+HIL+A GG+ P NIPG E G DS+GFF L Sbjct: 117 VIKGFAKFVDEKTVEVNG-----EHYTADHILIAVGGRPTIP-NIPGAEYGIDSNGFFDL 170 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 EQPK+V VVGAGYI +E+AGV H LG+ETHL +R E+ LR FD I +T+ + EG Sbjct: 171 AEQPKRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGP 230 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNS 312 +H S +V K + L +H+ + +S +VD+LIW IGR + + G+ N Sbjct: 231 TLHTHSVPKEVVKEADGS-LTLHLENGES-QNVDQLIWAIGRHPATDAINLASTGVATNE 288 Query: 313 HDQIIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYEN 371 I DEYQ TNV IY +GD++ G +ELTPVA+ AGR+LS RLF + N K+DY+ Sbjct: 289 KGYIKVDEYQETNVKGIYCVGDIMEGGIELTPVAVKAGRQLSERLFNNKP--NAKMDYDL 346 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 VP+V+FSHP G+IG++ +EA EKYGK+NIKVY S FTAMY A+ + P + K+VCAG Sbjct: 347 VPTVVFSHPPIGTIGLTTQEAEEKYGKDNIKVYTSGFTAMYTAVTKHRQPCKMKLVCAGE 406 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 E VVGLH +G + E++QGFGVA+KMGATKADFD+ VAIHPT +EE VTMR Sbjct: 407 EETVVGLHGIGFTVDEMIQGFGVAMKMGATKADFDSVVAIHPTGSEEFVTMR 458 >2AAQ-A nrPDB Length = 479 Score = 526 bits (1356), Expect = e-150, Method: Composition-based stats. Identities = 236/472 (50%), Positives = 305/472 (64%), Gaps = 24/472 (5%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82 YDYLVIGGGSGG+ASARRAA GA+ +VE+ LGGTCVNVGCVPKKVMW + + + Sbjct: 21 SYDYLVIGGGSGGLASARRAAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFM 80 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 +YG FNW K+KRDAYV RLN IYQ NL K ++++ G A F Sbjct: 81 HDHADYGFPSCEG------KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFT 134 Query: 143 KDG--NVEVQKRDNTTEVYSANHILVATGGKAIFP--ENIPGFELGTDSDGFFRLEEQPK 198 D +EV + Y+A HIL+ATGG P IPG LG SDGFF+LEE P Sbjct: 135 SDPKPTIEVSGKK-----YTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPG 189 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 + V+VGAGYI +E+AG+ LGS+T L+IR + VLR FD I T+ G+ V K Sbjct: 190 RSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKF 249 Query: 259 SKIVKVEKNVETDKLK-IHMNDSK-----SIDDVDELIWTIGRKSHL-GMGSENVGIKLN 311 S++ +V+K + ++ + + I DVD L+W IGR + + +GI+ + Sbjct: 250 SQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTD 309 Query: 312 SHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYEN 371 II DE+QNTNV IY++GDV GK LTPVAIAAGRKL++RLF E + KLDY N Sbjct: 310 DKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLF--EYKEDSKLDYNN 367 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 +P+V+FSHP G++G++E EAI KYG EN+K Y++ FT MY+A+ K+ K+VCA Sbjct: 368 IPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANK 427 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 EKVVG+H+ G E+LQGF VA+KMGATKADFDN VAIHPTS+EELVT+R Sbjct: 428 EEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 479 >5V36-A nrPDB Length = 453 Score = 523 bits (1347), Expect = e-149, Method: Composition-based stats. Identities = 233/466 (50%), Positives = 309/466 (66%), Gaps = 18/466 (3%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 TK YDY+VIGGGSGG+ASA RAA +GAK +L E K +GGTCVNVGCVPKKVMWY + +A Sbjct: 4 MTKQYDYIVIGGGSGGIASANRAAMHGAKVILFEGKQVGGTCVNVGCVPKKVMWYGAQVA 63 Query: 80 TRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 ++ +A +YG D F++ KQ R AY+ R++ Y++ + V+ V+G+ Sbjct: 64 ETINNYAADYGF------DVTTQAFHFDVLKQNRQAYIDRIHDSYERGFDSNGVERVYGY 117 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK 198 A F VEV E Y+A HIL+ATGG A+ P +IPG E G SDGFF L+ PK Sbjct: 118 ATFVDAHTVEVAG-----EHYTAPHILIATGGHALLP-DIPGSEYGITSDGFFELDAIPK 171 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 + VVGAGYI +E++G+ H LGSETHL +R + LRKFD+ I T+ D K+G ++H Sbjct: 172 RTAVVGAGYIAVEISGILHALGSETHLFVRRDRPLRKFDKEIVGTLVDEMKKDGPHLHTF 231 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQII 317 S +V KN + I N + VD LIW IGR ++ G E G+ L+S I Sbjct: 232 SVPKEVIKNTDNSLTLILENGEE--YTVDTLIWAIGRAANTKGFNLEVTGVTLDSRGFIA 289 Query: 318 ADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 D ++NTNV +Y+LGDV GK+ELTPVA+ AGR+LS RLF + K+DY++V +VIF Sbjct: 290 TDAFENTNVEGLYALGDVNGKLELTPVAVKAGRQLSERLFNHKP--QAKMDYKDVATVIF 347 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVG 437 SHP GSIG+SE+ A+++YG+EN+ VY S FT+MY A+ S + + K+V G +EK+VG Sbjct: 348 SHPVIGSIGLSEEAALDQYGEENVTVYRSTFTSMYTAVTSHRQACKMKLVTVGEDEKIVG 407 Query: 438 LHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 LH +G E++QGF VAIKMGATKADFDN VAIHPT +EE VTMR Sbjct: 408 LHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 453 >6B4O-A nrPDB Length = 452 Score = 520 bits (1339), Expect = e-148, Method: Composition-based stats. Identities = 213/468 (45%), Positives = 295/468 (63%), Gaps = 18/468 (3%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S K YDY+VIGGGSGG+ASA RA +GA LL+E +GGTCVNVGCVPKKVMW AS Sbjct: 1 SNAMKTYDYIVIGGGSGGIASANRAGMHGANVLLIEGNEIGGTCVNVGCVPKKVMWQASS 60 Query: 78 LATRV-SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 + + YG D E F++ + + R+ Y+ L+G Y + L+ ++ + Sbjct: 61 MMEMMERDTAGYGF------DVEIKNFSFKQLVENREKYIDFLHGAYNRGLDSNNIERIH 114 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQ 196 G+A F + +EV + Y+A HIL+ATGG+ IPG E DS+GFF LEE Sbjct: 115 GYATFTGEQTIEVNGTE-----YTAPHILIATGGRPK-KLGIPGEEYALDSNGFFALEEM 168 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 PK+VV VGAGYI ELAG HGLG+ETH R E LR FD+ + + + Y + G+ +H Sbjct: 169 PKRVVFVGAGYIAAELAGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMGMQIH 228 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQ 315 + K+EK + + + I + +S D +I+ GR+ + +G EN + L+ Sbjct: 229 PNATPAKIEKTAQNEYV-ITFENGES-ITTDAVIFGTGRQPNTDQLGLENTKVALDEKGY 286 Query: 316 IIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSV 375 + D++QNT IY++GDV+GK++LTPVAIAAGR+LS RLF + + LDY VP+V Sbjct: 287 VKVDKFQNTTQNGIYAVGDVIGKIDLTPVAIAAGRRLSERLFNGQT--DLYLDYNLVPTV 344 Query: 376 IFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKV 435 +F+HP +IG++EK A+E+YG++ +K+Y S FT MY+A+ + K++C G EK+ Sbjct: 345 VFTHPPVATIGLTEKAALEEYGEDQVKIYRSSFTPMYFALGEYRQKCDMKLICVGKEEKI 404 Query: 436 VGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTMR 483 VGLH +G E+LQGF VAIKMGATKADFDN VAIHPT +EE VTMR Sbjct: 405 VGLHGIGIGVDEMLQGFAVAIKMGATKADFDNTVAIHPTGSEEFVTMR 452 >1ZDL-A nrPDB Length = 517 Score = 518 bits (1335), Expect = e-147, Method: Composition-based stats. Identities = 166/483 (34%), Positives = 255/483 (52%), Gaps = 27/483 (5%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVP 68 + + +D LVIGGGSGG+A A+ AA G K + + LGGTCVNVGC+P Sbjct: 27 AGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIP 86 Query: 69 KKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLE 128 KK+M A+ L + A+ YG P + NW + +V LN ++ L+ Sbjct: 87 KKLMHQAALLGGMIRDAHHYGWEVAQP-----VQHNWKTMAEAVQNHVKSLNWGHRVQLQ 141 Query: 129 KEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDS 187 KV A F + V + + SA HI++ATGG+ +P + G E G S Sbjct: 142 DRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITS 201 Query: 188 DGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDH 247 D F L+E P K +VVGA Y+ +E AG G+G +T +++R LR FD+ + + +T+H Sbjct: 202 DDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMR-SIPLRGFDQQMSSLVTEH 260 Query: 248 YVKEGINVHKLSKIVKVEK---NVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGS 303 G K ++K N + H + + D ++W IGR + Sbjct: 261 MESHGTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNL 320 Query: 304 ENVGIKLNSHDQ-IIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEK 361 E GI N +Q II D + T+VP+IY++GDV G+ ELTP AI AG+ L+ RLFG Sbjct: 321 EKAGISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSS 380 Query: 362 FRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP 421 +DY NVP+ +F+ E G +G+SE+EA+ +G+E+++VY++ + + + + + Sbjct: 381 TL---MDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDAS 437 Query: 422 -TRYKIVCAGP-NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 K+VC + V+GLH +G ++ E+ QGF + IK GA+ A V IHPT +EE+ Sbjct: 438 QCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEV 497 Query: 480 VTM 482 V + Sbjct: 498 VKL 500 >6DU7-A nrPDB Length = 448 Score = 515 bits (1328), Expect = e-146, Method: Composition-based stats. Identities = 193/446 (43%), Positives = 266/446 (59%), Gaps = 17/446 (3%) Query: 39 ARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDK 98 RA +GA+ ++E K LGGTCVNVGCVPKK+MWY + +A ++ Sbjct: 19 MNRAGEHGAQAAVIEEKKLGGTCVNVGCVPKKIMWYGAQIAETFHQ-----FGEDYGFKT 73 Query: 99 EHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEV 158 L F++ ++ R++Y+ R Y + ++ VD++ G A F V V E+ Sbjct: 74 TDLNFDFATLRRNRESYIDRARSSYDGSFKRNGVDLIEGHAEFVDSHTVSVNG-----EL 128 Query: 159 YSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHG 218 A HI++ATG P NIPG ELG SD F EE P+ V ++GAGYI +ELAGV H Sbjct: 129 IRAKHIVIATGAHPSIP-NIPGAELGGSSDDVFAWEELPESVAILGAGYIAVELAGVLHT 187 Query: 219 LGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMN 278 G +T L +R + LR FD I + + + +H VK+EK + + IH Sbjct: 188 FGVKTDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTHKVPVKLEKTTDG--ITIHFE 245 Query: 279 DSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVG 337 D + ++IW GR+ ++ G+ E G+ LN I DEYQNT V IY+LGDV G Sbjct: 246 DG-TSHTASQVIWATGRRPNVKGLQLEKAGVTLNERGFIQVDEYQNTVVEGIYALGDVTG 304 Query: 338 KVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYG 397 + ELTPVAI AGR LS RLF + K+DY +P+V+FSHP G++G++E++AI++YG Sbjct: 305 EKELTPVAIKAGRTLSERLFNGKT--TAKMDYSTIPTVVFSHPAIGTVGLTEEQAIKEYG 362 Query: 398 KENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIK 457 ++ IKVY S F +MY A + +R+K++ AG EKVVGLH +G E++QGF VAIK Sbjct: 363 QDQIKVYKSSFASMYSACTRNRQESRFKLITAGSEEKVVGLHGIGYGVDEMIQGFAVAIK 422 Query: 458 MGATKADFDNCVAIHPTSAEELVTMR 483 MGATKADFD VAIHPTS+EE VTMR Sbjct: 423 MGATKADFDATVAIHPTSSEEFVTMR 448 >2X8H-A nrPDB Length = 598 Score = 515 bits (1327), Expect = e-146, Method: Composition-based stats. Identities = 170/485 (35%), Positives = 269/485 (55%), Gaps = 33/485 (6%) Query: 22 KHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVM 72 YD +VIGGGSGG+A+ + AA YGAKT +++ LGGTCVNVGC+PKK+M Sbjct: 106 YDYDLIVIGGGSGGLAAGKEAAKYGAKTAVLDYVEPTPIGTTWGLGGTCVNVGCIPKKLM 165 Query: 73 WYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 A L+ + A +G LD+ ++ NW + +++ LN Y+ L +V Sbjct: 166 HQAGLLSHALEDAEHFGW----SLDRSKISHNWSTMVEGVQSHIGSLNWGYKVALRDNQV 221 Query: 133 DVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFF 191 + R V++ ++ + N I++ATG + +P IPG E G SD F Sbjct: 222 TYLNAKGRLISPHEVQITDKNQKVSTITGNKIILATGERPKYP-EIPGAVEYGITSDDLF 280 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 L P K +V+GA Y+ +E AG LG + +++R +LR FD+ + + D+ Sbjct: 281 SLPYFPGKTLVIGASYVALECAGFLASLGGDVTVMVR-SILLRGFDQQMAEKVGDYMENH 339 Query: 252 GINVHKLSKIVKVEKNVETDK---------LKIHMNDSKS-IDDVDELIWTIGRKSHLG- 300 G+ KL ++++ D +K H D K ++ + +I+ +GR+ L Sbjct: 340 GVKFAKLCVPDEIKQLKVVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSK 399 Query: 301 MGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV-VGKVELTPVAIAAGRKLSNRLFGP 359 + E VG+KL+ + +++ + + T V N+Y++GD+ GK +LTPVAI AGR L+ RLF Sbjct: 400 VLCETVGVKLDKNGRVVCTDDEQTTVSNVYAIGDINAGKPQLTPVAIQAGRYLARRLFAG 459 Query: 360 EKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEK 419 + DY NV + +F+ E G+ G+SE++AIEKYG ++I+VY+S F + + + + Sbjct: 460 A---TELTDYSNVATTVFTPLEYGACGLSEEDAIEKYGDKDIEVYHSNFKPLEWTVAHRE 516 Query: 420 SP-TRYKIVCAG-PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 K+VC N +V+GLH++G ++ EI QG+ VAIKMGATKADFD + IHPT +E Sbjct: 517 DNVCYMKLVCRKSDNMRVLGLHVLGPNAGEITQGYAVAIKMGATKADFDRTIGIHPTCSE 576 Query: 478 ELVTM 482 T+ Sbjct: 577 TFTTL 581 >4LA1-A nrPDB Length = 602 Score = 509 bits (1312), Expect = e-145, Method: Composition-based stats. Identities = 159/467 (34%), Positives = 254/467 (54%), Gaps = 33/467 (7%) Query: 40 RRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL 90 + AA YGAK +++ LGGTCVNVGC+PKK+M A L+ + A +G Sbjct: 130 KEAAKYGAKIAVLDYVEPTPMGTTWGLGGTCVNVGCIPKKLMHQAGLLSHSLEDAQHFGW 189 Query: 91 YQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQ 150 LDK ++ +W + +++ LN Y+ +L V + V++ Sbjct: 190 ----SLDKSEISHDWSTMVEGVQSHIGSLNWGYKVSLRDNAVTYLNARGMLLSPHEVQIT 245 Query: 151 KRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFFRLEEQPKKVVVVGAGYIG 209 +++ + N I++ATG + +P IPG E G SD F L P K +VVGA Y+ Sbjct: 246 EKNKKVSTITGNKIILATGERPKYP-EIPGAIEYGITSDDLFSLPYFPGKTLVVGASYVA 304 Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVE--KN 267 ++ AG LG + +++R +LR FD+ + + D+ G+ KL ++ K Sbjct: 305 LKCAGFLASLGGDVTVMVR-SILLRGFDQQMAEKVGDYMENHGVKFAKLCVPDEITQLKP 363 Query: 268 VETDK-------LKIHMNDSKS-IDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQIIA 318 V+T+ +K H D K ++ + +I+ +GR+ L + E VG+KL+ + +++ Sbjct: 364 VDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKLNCEAVGVKLDKNGRVVC 423 Query: 319 DEYQNTNVPNIYSLGDV-VGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 + + T V NIY++GD+ GK +LTPVAI AGR L+ RLF + DY NV + +F Sbjct: 424 SDDEQTTVSNIYAIGDINAGKPQLTPVAIHAGRYLARRLFAGA---TELTDYSNVATTVF 480 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP-TRYKIVCA-GPNEKV 435 + E G+ G+SE++AIEKYG +I+VY+S F + + + + K+VC N +V Sbjct: 481 TPLEYGACGLSEEDAIEKYGDNDIEVYHSHFKPLEWTVAHREDNVCYMKLVCRISDNMRV 540 Query: 436 VGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 +GLH++G ++ EI QG+ VAIKMGATK DFD + IHPT +E T+ Sbjct: 541 LGLHVLGPNAGEITQGYAVAIKMGATKEDFDRTIGIHPTCSETFTTL 587 >2WOV-A nrPDB Length = 495 Score = 507 bits (1305), Expect = e-144, Method: Composition-based stats. Identities = 165/486 (33%), Positives = 250/486 (51%), Gaps = 32/486 (6%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAAS-YGAKTLLVEAK---------ALGGTCVNVGCV 67 S +K +D +VIG GSGG+ + AA+ YG + +V+ + ALGGTCVNVGCV Sbjct: 2 SHMSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCVNVGCV 61 Query: 68 PKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL 127 PKK+M + + + +G D + NW + ++ V +N Y+ Sbjct: 62 PKKLMVTGAQYMDHLRESAGFGW----EFDGSSVKANWKKLIAAKNEAVLDINKSYEGMF 117 Query: 128 -EKEKVDVVFGWARFNKDGNVEVQKRDNTT----EVYSANHILVATGGKAIFPENIPGFE 182 + E +D GW V V++ + E A+HIL+ATG P IPG E Sbjct: 118 NDTEGLDFFLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMP-AIPGIE 176 Query: 183 LGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL---GSETHLVIRGETVLRKFDEC 239 S+ F L E P++V+ VG G+I +E AG+F+ G + L R +LR FDE Sbjct: 177 HCISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDET 236 Query: 240 IQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 I+ +T GI + KV N + K + K++ DVD ++ IGR Sbjct: 237 IREEVTKQLTANGIEIMTNENPAKVSLNTDGSK-HVTFESGKTL-DVDVVMMAIGRIPRT 294 Query: 300 -GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFG 358 + NVG+KL + DE+ TNVPNIY++GD+ ++ LTPVAI G L + +FG Sbjct: 295 NDLQLGNVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITDRLMLTPVAINEGAALVDTVFG 354 Query: 359 PEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSE 418 + K D+ V S +FS P G+ G+ E+ A +++ E + VY S FT + + + Sbjct: 355 N---KPRKTDHTRVASAVFSIPPIGTCGLIEEVAAKEF--EKVAVYMSSFTPLMHNISGS 409 Query: 419 KSPTRY-KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 K KIV + V+G+H++GD + EI+Q GV +++ A +DF N + +HPTSAE Sbjct: 410 KYKKFVAKIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLRLNAKISDFYNTIGVHPTSAE 469 Query: 478 ELVTMR 483 EL +MR Sbjct: 470 ELCSMR 475 >2YAU-A nrPDB Length = 511 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 158/486 (32%), Positives = 251/486 (51%), Gaps = 32/486 (6%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAA-SYGAKTLLVEAKA---------LGGTCVNVGCV 67 S ++ YD +V+G GSGG+ + AA ++ K +V+ +A LGGTCVNVGCV Sbjct: 19 SHMSRAYDLVVLGAGSGGLEAGWNAAVTHKKKVAVVDVQATHGPPLFAALGGTCVNVGCV 78 Query: 68 PKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL 127 PKK+M + + + +G +D+E L NW ++ V+ +N Y+ Sbjct: 79 PKKLMVTGAQYMDLIRESGGFGW----EMDRESLCPNWKTLIAAKNKVVNSINESYKSMF 134 Query: 128 -EKEKVDVVFGWARFNKDGNVEVQKRDNTT----EVYSANHILVATGGKAIFPENIPGFE 182 + E + G+ V V+K ++ E +IL+ATG +PG E Sbjct: 135 ADTEGLSFHMGFGALQDAHTVVVRKSEDPHSDVLETLDTEYILIATGSWPTR-LGVPGDE 193 Query: 183 LGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL---GSETHLVIRGETVLRKFDEC 239 S+ F LE+ PK+++ VG GYI +E AG+F+G G L RG+ +LR FD Sbjct: 194 FCITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTE 253 Query: 240 IQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 ++ ++T GI V K+ KN + +H ND + +D D+++ IGR Sbjct: 254 VRKSLTKQLGANGIRVRTNLNPTKITKNEDGSN-HVHFNDG-TEEDYDQVMLAIGRVPRS 311 Query: 300 -GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFG 358 + + G++ + + D Y T+V NIY++GDV +V LTPVAI G +FG Sbjct: 312 QALQLDKAGVRTGKNGAVQVDAYSKTSVDNIYAIGDVTNRVMLTPVAINEGAAFVETVFG 371 Query: 359 PEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSE 418 + D+ V +FS P G+ G++E+EA + Y E + VY S FT + + + Sbjct: 372 G---KPRATDHTKVACAVFSIPPIGTCGMTEEEAAKNY--ETVAVYASSFTPLMHNISGS 426 Query: 419 KSPTRY-KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 K +I+ N +V+G+H++GDS+ EI+Q G+ +KMGA +DF + + +HPTSAE Sbjct: 427 KHKEFMIRIITNESNGEVLGVHMLGDSAPEIIQSVGICMKMGAKISDFHSTIGVHPTSAE 486 Query: 478 ELVTMR 483 EL +MR Sbjct: 487 ELCSMR 492 >4KPR-E nrPDB Length = 499 Score = 497 bits (1280), Expect = e-141, Method: Composition-based stats. Identities = 155/464 (33%), Positives = 248/464 (53%), Gaps = 31/464 (6%) Query: 40 RRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL 90 + AA + K ++++ LGGTCVNVGC+PKK+M A+ L + + YG Sbjct: 29 KEAAKFDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGW 88 Query: 91 YQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQ 150 + + +W + + ++ LN Y+ L ++KV + +F + Sbjct: 89 KLE-----DTVKHDWEKMTESVQNHIGSLNWGYRVALREKKVVYENAYGKFIGPHKIMAT 143 Query: 151 KRDNTTEVYSANHILVATGGKAIFPENIPGF-ELGTDSDGFFRLEEQPKKVVVVGAGYIG 209 +VYSA L+ATG + + IPG E SD F L P K +VVGA Y+ Sbjct: 144 NNKGKEKVYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVA 202 Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVE 269 +E AG G+G + +++R +LR FD+ + N I +H + GI + K+E+ Sbjct: 203 LECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEA 261 Query: 270 TD----KLKIHMNDSKSID--DVDELIWTIGRKSHL-GMGSENVGIKLNSH-DQIIADEY 321 K+ +S+ + + ++ +GR S +G E VG+K+N +I + Sbjct: 262 GTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDE 321 Query: 322 QNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHP 380 + TNVP IY++GD++ GK+ELTPVAI AGR L+ RL+G K DY+NVP+ +F+ Sbjct: 322 EQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTV---KCDYDNVPTTVFTPL 378 Query: 381 EAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY-KIVCA-GPNEKVVGL 438 E G G+SE++A+EK+G+ENI+VY+S F + + + S + Y K++C NE+VVG Sbjct: 379 EYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKVICNLKDNERVVGF 438 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 H++G ++ E+ QGF A+K G TK D+ + IHP AE T+ Sbjct: 439 HVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTL 482 >5U8W-A nrPDB Length = 481 Score = 497 bits (1279), Expect = e-141, Method: Composition-based stats. Identities = 128/471 (27%), Positives = 230/471 (48%), Gaps = 20/471 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-------ALGGTCVNVGCVPKK 70 S ++ +D +VIG G GG +A RAA G KT +E ALGGTC+NVGC+P K Sbjct: 2 SHMSQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSK 61 Query: 71 VMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKE 130 + +S A ++ ++ + +T + P ++ V L G + Sbjct: 62 ALLDSSYKYHEAKEA-----FKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKAN 116 Query: 131 KVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-FPENIPGFELGTDSDG 189 V G + + VEV D T+V A ++++A+G + + P ++ DS G Sbjct: 117 GVTSFEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLTDDIIVDSTG 176 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 + PKK+ V+GAG IG+EL V+ LG+E ++ + L DE I Sbjct: 177 ALEFQAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLT 236 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS-HLGMGSENVGI 308 K+G+N+ +++ E + + + + + D+LI +GR+ + + + G+ Sbjct: 237 KQGLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGV 296 Query: 309 KLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLD 368 L+ I D++ T+VP ++++GDVV L A G ++ R+ G + +++ Sbjct: 297 TLDERGFIYVDDHCKTSVPGVFAIGDVVRGAMLAHKASEEGVMVAERIAGHK----AQMN 352 Query: 369 YENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVC 428 Y+ +PSVI++HPE +G +E + ++ G E + V F A AM + + K++ Sbjct: 353 YDLIPSVIYTHPEIAWVGKTE-QTLKAEGVE-VNVGTFPFAASGRAMAANDTTGLVKVIA 410 Query: 429 AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G+H++G S+AE++Q + ++ G + D V HPT +E L Sbjct: 411 DAKTDRVLGVHVIGPSAAELVQQGAIGMEFGTSAEDLGMMVFSHPTLSEAL 461 >4NEW-A nrPDB Length = 492 Score = 496 bits (1278), Expect = e-141, Method: Composition-based stats. Identities = 161/485 (33%), Positives = 244/485 (50%), Gaps = 33/485 (6%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAAS-YGAKTLLVEAK---------ALGGTCVNVGCVP 68 K +D +VIG GSGG+ +A AA+ Y + +++ + ALGGTCVNVGCVP Sbjct: 1 MMPKIFDLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCVNVGCVP 60 Query: 69 KKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLE 128 KK+M + + + +G D+ L W +D V +N Y + Sbjct: 61 KKLMVTGAQYMEHLRESAGFGW----EFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFR 116 Query: 129 K-EKVDVVFGWARFNKDGNVEVQKRDNT----TEVYSANHILVATGGKAIFPENIPGFEL 183 E ++ GW V V++ + E HIL+A+G P NIPG E Sbjct: 117 DTEGLEFFLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMP-NIPGIEH 175 Query: 184 GTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLG---SETHLVIRGETVLRKFDECI 240 S+ F L E P++V+ VG G+I +E AG+F+ + L RGE +LR FD + Sbjct: 176 CISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTL 235 Query: 241 QNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL- 299 + +T GI + KVE N + K + K + D D ++ IGR Sbjct: 236 REELTKQLTANGIQILTKENPAKVELNADGSK-SVTFESGKKM-DFDLVMMAIGRSPRTK 293 Query: 300 GMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGP 359 + +N G+ + + + DEY TNV NIY++GDV +V LTPVAI L + +FG Sbjct: 294 DLQLQNAGVMI-KNGGVQVDEYSRTNVSNIYAIGDVTNRVMLTPVAINEAAALVDTVFGT 352 Query: 360 EKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEK 419 K D+ V S +FS P G+ G+ E+ A ++Y E + VY S FT + + + K Sbjct: 353 TP---RKTDHTRVASAVFSIPPIGTCGLIEEVASKRY--EVVAVYLSSFTPLMHKVSGSK 407 Query: 420 SPTRY-KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEE 478 T KI+ + V+G+H++GD++ EI+QG G+ +K+ A +DF N + +HPTSAEE Sbjct: 408 YKTFVAKIITNHSDGTVLGVHLLGDNAPEIIQGIGICLKLNAKISDFYNTIGVHPTSAEE 467 Query: 479 LVTMR 483 L +MR Sbjct: 468 LCSMR 472 >2CFY-A nrPDB Length = 521 Score = 495 bits (1276), Expect = e-140, Method: Composition-based stats. Identities = 159/464 (34%), Positives = 250/464 (53%), Gaps = 31/464 (6%) Query: 40 RRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGL 90 + AA YG K ++++ LGGTCVNVGC+PKK+M A+ L + + YG Sbjct: 51 KEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGW 110 Query: 91 YQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQ 150 E + +W + ++ LN Y+ L ++KV + +F ++ Sbjct: 111 KVE-----ETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKAT 165 Query: 151 KRDNTTEVYSANHILVATGGKAIFPENIPGF-ELGTDSDGFFRLEEQPKKVVVVGAGYIG 209 ++YSA L+ATG + + IPG E SD F L P K +VVGA Y+ Sbjct: 166 NNKGKEKIYSAERFLIATGERPRY-LGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVA 224 Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVE 269 +E AG G+G + +++R +LR FD+ + N I +H + GI + +KVE+ Sbjct: 225 LECAGFLAGIGLDVTVMVR-SILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEA 283 Query: 270 TD----KLKIHMNDSKSID--DVDELIWTIGRKSHL-GMGSENVGIKLNSH-DQIIADEY 321 ++ +S+ I + + ++ IGR + +G E VG+K+N +I + Sbjct: 284 GTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDE 343 Query: 322 QNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHP 380 + TNVP IY++GD++ KVELTPVAI AGR L+ RL+ K DYENVP+ +F+ Sbjct: 344 EQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTV---KCDYENVPTTVFTPL 400 Query: 381 EAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY-KIVCA-GPNEKVVGL 438 E G+ G+SE++A+EK+G+ENI+VY+S F + + + S + Y KI+C NE+VVG Sbjct: 401 EYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGF 460 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 H++G ++ E+ QGF A+K G TK D+ + IHP AE T+ Sbjct: 461 HVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTL 504 >5TR3-A nrPDB Length = 481 Score = 492 bits (1267), Expect = e-139, Method: Composition-based stats. Identities = 128/469 (27%), Positives = 227/469 (48%), Gaps = 20/469 (4%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-------ALGGTCVNVGCVPKKVM 72 T+ +D +VIG G GG +A +AA G KT +E ALGGTC+NVGC+P K + Sbjct: 4 MTQKFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKAL 63 Query: 73 WYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 +S + + + + + ++ V L G + V Sbjct: 64 LDSSWKYKEAKES-----FNVHGISTGEVKMDVAAMVGRKAGIVKNLTGGVATLFKANGV 118 Query: 133 DVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-FPENIPGFELGTDSDGFF 191 + G + VEV K D TTEV A ++++A+G + I P + DS G Sbjct: 119 TSIQGHGKLLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGAL 178 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 + PK++ V+GAG IG+EL V+ LG+E ++ +T L D + K+ Sbjct: 179 EFQAVPKRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQ 238 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS-HLGMGSENVGIKL 310 G+++ +++ + N ++ + + D+LI +GR+ + + + G+ + Sbjct: 239 GLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGVTI 298 Query: 311 NSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYE 370 + I D+Y T+VP +Y++GDVV + L A G + R+ G + +++Y+ Sbjct: 299 DERGYIFVDDYCATSVPGVYAIGDVVRGMMLAHKASEEGIMVVERIKGHK----AQMNYD 354 Query: 371 NVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAG 430 +PSVI++HPE +G +E +A++ G E + V F A AM + + K++ Sbjct: 355 LIPSVIYTHPEIAWVGKTE-QALKAEGVE-VNVGTFPFAASGRAMAANDTGGFVKVIADA 412 Query: 431 PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G+H++G S+AE++Q +A++ G + D V HPT +E L Sbjct: 413 KTDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFSHPTLSEAL 461 >1FEC-A nrPDB Length = 490 Score = 490 bits (1261), Expect = e-139, Method: Composition-based stats. Identities = 157/483 (32%), Positives = 245/483 (50%), Gaps = 32/483 (6%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAK-TLLVEAK---------ALGGTCVNVGCVPKK 70 ++ YD +VIG GSGG+ + AAS K +++ + ALGGTCVNVGCVPKK Sbjct: 1 SRAYDLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCVNVGCVPKK 60 Query: 71 VMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL-EK 129 +M ++ + + +G LD+E + NW ++ V +N Y+ + Sbjct: 61 LMVTGANYMDTIRESAGFGW----ELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADT 116 Query: 130 EKVDVVFGWARFNKDGNVEVQKRDNTT----EVYSANHILVATGGKAIFPENIPGFELGT 185 E + G+ + V V++ + E +IL+ATG I G +L Sbjct: 117 EGLTFHQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQH-LGIEGDDLCI 175 Query: 186 DSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL---GSETHLVIRGETVLRKFDECIQN 242 S+ F L+E PK+ + VG GYI IE AG+F+ G + L RG+ +LR FD ++ Sbjct: 176 TSNEAFYLDEAPKRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELRK 235 Query: 243 TITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-M 301 +T+ GINV KV KN + + + + +++ D D ++ IGR + Sbjct: 236 QLTEQLRANGINVRTHENPAKVTKNADGTRHVVFESGAEA--DYDVVMLAIGRVPRSQTL 293 Query: 302 GSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEK 361 E G+++ + I D Y TNV NIY++GDV +V LTPVAI G + +F Sbjct: 294 QLEKAGVEVAKNGAIKVDAYSKTNVDNIYAIGDVTDRVMLTPVAINEGAAFVDTVFAN-- 351 Query: 362 FRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP 421 + D+ V +FS P G G E++A +KY + + VY S FT + + + Sbjct: 352 -KPRATDHTKVACAVFSIPPMGVCGYVEEDAAKKY--DQVAVYESSFTPLMHNISGSTYK 408 Query: 422 TRY-KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELV 480 +IV + +V+G+H++GDSS EI+Q + +KMGA +DF N + +HPTSAEEL Sbjct: 409 KFMVRIVTNHADGEVLGVHMLGDSSPEIIQSVAICLKMGAKISDFYNTIGVHPTSAEELC 468 Query: 481 TMR 483 +MR Sbjct: 469 SMR 471 >5W1J-A nrPDB Length = 584 Score = 490 bits (1261), Expect = e-139, Method: Composition-based stats. Identities = 159/494 (32%), Positives = 261/494 (52%), Gaps = 36/494 (7%) Query: 14 IRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNV 64 ++ + YD ++IGGGSGG+A A+ +A GAK L++ LGGTCVNV Sbjct: 94 VKKANEMKYDYDMVIIGGGSGGLALAKESAKSGAKVALLDFVVPTPMGTTWGLGGTCVNV 153 Query: 65 GCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ 124 GC+PKK+M A+ L + A +G D + +W + + ++H LN Y+ Sbjct: 154 GCIPKKLMHQAALLNHYMEDAKSFGW------DVDKGPHDWVKMVEGIQDHIHALNFGYR 207 Query: 125 KNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGF-EL 183 ++ V + ++ + + + N I+VATG + +P IPG E Sbjct: 208 SSMMNANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNTIIVATGERPRYPP-IPGAKEY 266 Query: 184 GTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNT 243 G SD F L+ P K + VGA Y+ +E AG +G + +++R LR FD+ + Sbjct: 267 GITSDDLFTLDHNPGKTLCVGASYVSLECAGFLSSIGCDVTVMVR-SIFLRGFDQQMAGL 325 Query: 244 ITDHYVKEGINVHKLSKIVKV----EKNVETDKLKIHMNDSKSI------DDVDELIWTI 293 I+D+ K G+ + V E + E+ KL I+ + K D + +++ + Sbjct: 326 ISDYIAKYGVKFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAV 385 Query: 294 GRKS-HLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVG-KVELTPVAIAAGRK 351 GR +G +NV +K + +++ D+ + TNVPNIY++GDV +LTP+AI AG+ Sbjct: 386 GRDPCTTNIGLQNVDVKTT-NGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKN 444 Query: 352 LSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAM 411 L+ RL+ + R DY NVP+ +F+ E G IG+SE+ AI K+G++NI+V++S F + Sbjct: 445 LARRLYTADDCR---TDYTNVPTTVFTPLEYGCIGLSEENAISKFGEDNIEVFHSYFQPL 501 Query: 412 YYAMLSEKSPTRY-KIVCAG-PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCV 469 + + T Y K++ + +VVG H+ G ++ E+ QG+ VA+ +GA K DFD + Sbjct: 502 EWTVPHRPDNTCYAKLIINKQDDNRVVGFHVFGPNAGEVTQGYAVAMHLGARKEDFDRTI 561 Query: 470 AIHPTSAEELVTMR 483 IHPT +E T+R Sbjct: 562 GIHPTCSETFTTLR 575 >5J5Z-A nrPDB Length = 496 Score = 484 bits (1246), Expect = e-137, Method: Composition-based stats. Identities = 132/472 (27%), Positives = 213/472 (45%), Gaps = 23/472 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYAS 76 + D VIG G GG +A +AA G KT+ +E LGGTC+NVGC+P K + S Sbjct: 23 ADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNS 82 Query: 77 DLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 ++H ++ + ++ + N + +++ V L G ++ KV V Sbjct: 83 HY-YHMAHGKDF---ASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVN 138 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTD----SDGFFR 192 G+ + V K D T+V +IL+ATG + PG + D S G Sbjct: 139 GYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTP---FPGITIDEDTIVSSTGALS 195 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLR-KFDECIQNTITDHYVKE 251 L++ P+K+VV+GAG IG+EL V+ LG++ V V D I K+ Sbjct: 196 LKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQ 255 Query: 252 GINVHKLSKIVKVEKNVET---DKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVG 307 G +K+ K + ++ + D L+ IGR+ +G E +G Sbjct: 256 GFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELG 315 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKL 367 I+L+ +I + T +PNIY++GDVV L A G + G + Sbjct: 316 IELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAV----HI 371 Query: 368 DYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIV 427 DY VPSVI++HPE +G SE++ +++ G E KV F A A + + KI+ Sbjct: 372 DYNCVPSVIYTHPEVAWVGKSEEQ-LKEEGIE-YKVGKFPFAANSRAKTNADTDGMVKIL 429 Query: 428 CAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G HI+G + E++ +A++ GA+ HPT +E Sbjct: 430 GQKSTDRVLGAHILGPGAGEMVNEAALALEYGASCEVIARVCHAHPTLSEAF 481 >2NVK-X nrPDB Length = 488 Score = 483 bits (1244), Expect = e-137, Method: Composition-based stats. Identities = 158/481 (32%), Positives = 255/481 (53%), Gaps = 30/481 (6%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE----------AKALGGTCVNVGCVPK 69 + YD +VIGGGS G+A A+ A GA+ ++ +GGTCVNVGC+PK Sbjct: 6 GSYDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPK 65 Query: 70 KVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEK 129 K+M AS L V A YG + + +W + Q ++ +N + + +L Sbjct: 66 KLMHQASLLGEAVHEAAAYGWNV-----DDKIKPDWHKLVQSVQNHIKSVNWVTRVDLRD 120 Query: 130 EKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSD 188 +KV+ + G F + + + +A ++A GG+ +P +IPG E G SD Sbjct: 121 KKVEYINGLGSFVDSHTLLAKLKSG-ERTITAQTFVIAVGGRPRYP-DIPGAVEYGITSD 178 Query: 189 GFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHY 248 F L+ +P K +VVGAGYIG+E AG GLG E +++R VLR FD+ + + Sbjct: 179 DLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVR-SIVLRGFDQQMAELVAASM 237 Query: 249 VKEGINVHKLSKIVKVEKNVETDKLKIHMN---DSKSIDDVDELIWTIGRKSHL-GMGSE 304 + GI + + + VEK + L + N +S D D ++W IGRK + + Sbjct: 238 EERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDVYDTVLWAIGRKGLVDDLNLP 297 Query: 305 NVGIKLNSHDQIIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFR 363 N G+ + D+I D + TNV NIY++GD++ GK ELTPVA+ AGR L+ RL+G Sbjct: 298 NAGVTV-QKDKIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGS--- 353 Query: 364 NDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEK-SPT 422 ++DY++V + +F+ E +G+SE++A++++G + I+V++ + + + + Sbjct: 354 TQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYC 413 Query: 423 RYKIVCAG-PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVT 481 K V +++V GLH +G + E++QGF A+K G T N V IHPT+AEE Sbjct: 414 YLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTR 473 Query: 482 M 482 + Sbjct: 474 L 474 >3O0H-A nrPDB Length = 484 Score = 482 bits (1242), Expect = e-136, Method: Composition-based stats. Identities = 159/466 (34%), Positives = 253/466 (54%), Gaps = 18/466 (3%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S + +D VIG GSGGV +AR A + G + + E +GGTCV GCVPKK+ +YAS Sbjct: 21 SMGSFDFDLFVIGSGSGGVRAARLAGALGKRVAIAEEYRIGGTCVIRGCVPKKLYFYASQ 80 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 A S + +G P+ FNW + ++ + RL G+Y++ L+ V + Sbjct: 81 YAQEFSKSIGFGWKYADPI------FNWEKLVAAKNKEISRLEGLYREGLQNSNVHIYES 134 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQP 197 A F + +E+ T E SA IL+ATG K + I G +L S+ F LE+ P Sbjct: 135 RAVFVDEHTLELSV---TGERISAEKILIATGAKIVSNSAIKGSDLCLTSNEIFDLEKLP 191 Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K +V+VG GYIG+E A +FHGLG +T L+ RG+ +LR FD ++ + D V +GI++ Sbjct: 192 KSIVIVGGGYIGVEFANIFHGLGVKTTLLHRGDLILRNFDYDLRQLLNDAMVAKGISIIY 251 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSH-LGMGSENVGIKLNSHDQI 316 + + +V+ + + + D ++ GR + G+G E G+K+N + Sbjct: 252 EATVSQVQSTENCYNVVLT---NGQTICADRVMLATGRVPNTTGLGLERAGVKVNEFGAV 308 Query: 317 IADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 + DE TNV +I+++GDV G ++LTPVAI F DY+ + + + Sbjct: 309 VVDEKMTTNVSHIWAVGDVTGHIQLTPVAIHDAMCFVKNAFENTSTTP---DYDLITTAV 365 Query: 377 FSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVV 436 FS PE G++G+SE++A+ +Y + +++Y + F M + K+V G + VV Sbjct: 366 FSQPEIGTVGLSEEDALHRY--KRVEIYRTVFRPMRNVLSGSPEKMFMKLVVDGESRIVV 423 Query: 437 GLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 G H++G+++ EI Q G+++K TK FD +A+HPT +EELVTM Sbjct: 424 GAHVLGENAGEIAQLIGISLKGKLTKDIFDKTMAVHPTMSEELVTM 469 >3LAD-A nrPDB Length = 476 Score = 481 bits (1239), Expect = e-136, Method: Composition-based stats. Identities = 124/468 (26%), Positives = 227/468 (48%), Gaps = 20/468 (4%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-------ALGGTCVNVGCVPKKVMW 73 ++ +D +VIG G GG +A ++A G KT L+E ALGGTC+NVGC+P K + Sbjct: 1 SQKFDVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKTALGGTCLNVGCIPSKALL 60 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVD 133 +S + ++ + + + P ++D V L G ++ V Sbjct: 61 DSSYKFHEAHES-----FKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANGVT 115 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-FPENIPGFELGTDSDGFFR 192 + G + VEV D +++V ++++A+G K + P ++ DS G Sbjct: 116 LFEGHGKLLAGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQDVIVDSTGALD 175 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 + P K+ V+GAG IG+EL V+ LG+E ++ + L DE + K+G Sbjct: 176 FQNVPGKLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQG 235 Query: 253 INVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS-HLGMGSENVGIKLN 311 + + +++ E + +K + + D+LI +GR+ + + + G+ L+ Sbjct: 236 LKILLGARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLD 295 Query: 312 SHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYEN 371 I D+Y T+VP +Y++GDVV L A G ++ R+ G + +++Y+ Sbjct: 296 ERGFIYVDDYCATSVPGVYAIGDVVRGAMLAHKASEEGVVVAERIAGHK----AQMNYDL 351 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 +P+VI++HPE +G +E +A++ G I V F A AM + + K++ Sbjct: 352 IPAVIYTHPEIAGVGKTE-QALKAEG-VAINVGVFPFAASGRAMAANDTAGFVKVIADAK 409 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G+H++G S+AE++Q +A++ G + D V HP +E L Sbjct: 410 TDRVLGVHVIGPSAAELVQQGAIAMEFGTSAEDLGMMVFAHPALSEAL 457 >3URH-A nrPDB Length = 491 Score = 479 bits (1234), Expect = e-136, Method: Composition-based stats. Identities = 127/467 (27%), Positives = 216/467 (46%), Gaps = 24/467 (5%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYASDLATR 81 YD +VIG G GG A +AA G K +VE + GGTC+NVGC+P K + +AS++ + Sbjct: 25 AYDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMFHQ 84 Query: 82 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 H E L ++ + N + +DA V +K K+D G + Sbjct: 85 AQHGLE-----ALGVEVANPKLNLQKMMAHKDATVKSNVDGVSFLFKKNKIDGFQGTGKV 139 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTD------SDGFFRLEE 195 G V V +V A ++++ATG IPG E+ D S G LE+ Sbjct: 140 LGQGKVSVTNEKGEEQVLEAKNVVIATGSDV---AGIPGVEVAFDEKTIVSSTGALALEK 196 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 255 P ++VVG G IG+EL V+ LG++ +V +T+L D + + K+GI+ Sbjct: 197 VPASMIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILGGMDGEVAKQLQRMLTKQGIDF 256 Query: 256 HKLSKIVKVEKNVETDKLKI--HMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNS 312 +K+ K+ + K+ + D + ++ GRK G+G G+ L+S Sbjct: 257 KLGAKVTGAVKSGDGAKVTFEPVKGGEATTLDAEVVLIATGRKPSTDGLGLAKAGVVLDS 316 Query: 313 HDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENV 372 ++ D + T++ +Y++GDVV L A G ++ + G + ++Y+ + Sbjct: 317 RGRVEIDRHFQTSIAGVYAIGDVVRGPMLAHKAEDEGVAVAEIIAG----QAGHVNYDVI 372 Query: 373 PSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPN 432 P V+++ PE S+G +E+E K K+ FTA A ++ KI+ Sbjct: 373 PGVVYTQPEVASVGKTEEEL--KAAGVAYKIGKFPFTANGRARAMLQTDGFVKILADKET 430 Query: 433 EKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G HI+G + E++ V ++ G + D HPT +E + Sbjct: 431 DRVLGGHIIGFGAGEMIHEIAVLMEFGGSSEDLGRTCHAHPTMSEAV 477 >4B1B-A nrPDB Length = 542 Score = 476 bits (1225), Expect = e-135, Method: Composition-based stats. Identities = 159/495 (32%), Positives = 263/495 (53%), Gaps = 45/495 (9%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKK 70 +T YDY+VIGGG GG+ASA+ AA++GA+ LL + +GGTCVNVGCVPKK Sbjct: 39 HTYDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKK 98 Query: 71 VMWYASDLATRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEK 129 +M YA + + + YG ++L +W + +++ LN Y L Sbjct: 99 LMHYAGHMGSIFKLDSKAYGWKF------DNLKHDWKKLVTTVQSHIRSLNFSYMTGLRS 152 Query: 130 EKVDVVFGWARFNKDGNVEVQKRDN--TTEVYSANHILVATGGKAIFPENIPGF-ELGTD 186 KV + G A+ V + + E + +IL+ATG + P+++ G EL Sbjct: 153 SKVKYINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSIT 212 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD 246 SD F L++ P K +VVGA Y+ +E +G + LG + + +R VLR FD+ + Sbjct: 213 SDDIFSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVR-SIVLRGFDQQCAVKVKL 271 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSEN 305 + ++G+ K+ K + K+ + +D K+ + D +++ IGRK + G+ E+ Sbjct: 272 YMEEQGVMFKNGILPKKLTKMDD--KILVEFSD-KTSELYDTVLYAIGRKGDIDGLNLES 328 Query: 306 VGIKLNS-HDQIIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRLFGPEKFR 363 + + +N +++IIAD TN+P+I+++GDV EL PVAI AG L+ RLF K Sbjct: 329 LNMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLF---KDS 385 Query: 364 NDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSP-- 421 ++ +DY +P+ I++ E G+ G SE++A E YGK N++V+ +F + + + + Sbjct: 386 DEIMDYSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIR 445 Query: 422 -------------TRYKIVC-AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDN 467 K+VC + +V+G H VG ++ E+ QG +A+++ K DFDN Sbjct: 446 AQKDEYDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALRLKVKKKDFDN 505 Query: 468 CVAIHPTSAEELVTM 482 C+ IHPT AE + + Sbjct: 506 CIGIHPTDAESFMNL 520 >1DXL-A nrPDB Length = 470 Score = 472 bits (1216), Expect = e-133, Method: Composition-based stats. Identities = 125/470 (26%), Positives = 228/470 (48%), Gaps = 22/470 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYAS 76 ++ + D ++IGGG GG +A +AA G KT +E + LGGTC+NVGC+P K + ++S Sbjct: 1 ASGSDENDVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSS 60 Query: 77 DLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 + H+ + N + ++ + ++D V L + +K KV V Sbjct: 61 HMYHEAKHS-----FANHGVKVSNVEIDLAAMMGQKDKAVSNLTRGIEGLFKKNKVTYVK 115 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG----TDSDGFFR 192 G+ +F + V + V HI++ATG +++PG + S G Sbjct: 116 GYGKFVSPSEISVDTIEGENTVVKGKHIIIATGSDV---KSLPGVTIDEKKIVSSTGALA 172 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 L E PKK+VV+GAGYIG+E+ V+ +GSE +V ++ D I+ K+G Sbjct: 173 LSEIPKKLVVIGAGYIGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQG 232 Query: 253 INVHKLSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIK 309 + +K+V V+ + + KL + ++I + D ++ + GR G+ + +G++ Sbjct: 233 MKFKLKTKVVGVDTSGDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVE 292 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 + +I+ +E +TNV +Y++GDV+ L A G L G + +DY Sbjct: 293 TDKLGRILVNERFSTNVSGVYAIGDVIPGPMLAHKAEEDGVACVEYLAG----KVGHVDY 348 Query: 370 ENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 + VP V++++PE S+G +E++ K +V F A A + + KI+ Sbjct: 349 DKVPGVVYTNPEVASVGKTEEQV--KETGVEYRVGKFPFMANSRAKAIDNAEGLVKIIAE 406 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +K++G+HI+ ++ E++ +A++ A+ D HPT +E + Sbjct: 407 KETDKILGVHIMAPNAGELIHEAAIALQYDASSEDIARVCHAHPTMSEAI 456 >1EBD-A nrPDB Length = 455 Score = 471 bits (1212), Expect = e-133, Method: Composition-based stats. Identities = 130/456 (28%), Positives = 223/456 (48%), Gaps = 14/456 (3%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82 + LV+G G GG +A RAA G K +VE LGG C+NVGC+P K + AS + Sbjct: 3 ETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALISASHRYEQA 62 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 H+ E G+ E++T ++ + ++ + + V +L G + L+ KV++V G A F Sbjct: 63 KHSEEMGIKA------ENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFV 116 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVV 202 V V D + + Y+ + ++ATG + I N DS G L E PK +VV Sbjct: 117 DANTVRVVNGD-SAQTYTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEVPKSLVV 175 Query: 203 VGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIV 262 +G GYIGIEL + G++ ++ +L F++ + I K+G+ V + Sbjct: 176 IGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNALAK 235 Query: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQIIADEY 321 E+ + + N D D ++ T+GR+ + +G E +GIK+ + I D+ Sbjct: 236 GAEEREDGVTVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIEVDQQ 295 Query: 322 QNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPE 381 T+VPNI+++GD+V L A G+ + + G +DY +P+V+FS PE Sbjct: 296 CRTSVPNIFAIGDIVPGPALAHKASYEGKVAAEAIAG----HPSAVDYVAIPAVVFSDPE 351 Query: 382 AGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIV 441 S+G E++A ++ ++ F A A+ + K+V + ++G I+ Sbjct: 352 CASVGYFEQQAKDE--GIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQII 409 Query: 442 GDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 G ++++++ G+AI+ G T D + HPT E Sbjct: 410 GPNASDMIAELGLAIEAGMTAEDIALTIHAHPTLGE 445 >1ONF-A nrPDB Length = 500 Score = 468 bits (1206), Expect = e-132, Method: Composition-based stats. Identities = 198/508 (38%), Positives = 296/508 (58%), Gaps = 62/508 (12%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 YD +VIGGGSGG+A+ARRAA + AK LVE LGGTCVNVGCVPKK+M+ A+ + + Sbjct: 3 YDLIVIGGGSGGMAAARRAARHNAKVALVEKSRLGGTCVNVGCVPKKIMFNAASVHDILE 62 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 ++ YG +FN P ++RD Y+ RLN IY++NL K+KVD+ G A F Sbjct: 63 NSRHYGF-------DTKFSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEGTASFLS 115 Query: 144 DGNVEVQKRDNTT---------EVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLE 194 + + ++ + E+ +IL+A G K +FP + G E SD FF ++ Sbjct: 116 ENRILIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPP-VKGIENTISSDEFFNIK 174 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 E KK+ +VG+GYI +EL V LG ++++ RG +LRKFDE + N + + K IN Sbjct: 175 ES-KKIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNIN 233 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSH 313 + + +V+++K V L IH++D + + D +I+ +GR + E + ++ N + Sbjct: 234 IVTFADVVEIKK-VSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLNVETN-N 291 Query: 314 DQIIADEYQNTNVPNIYSLGDVV----------------------------------GKV 339 + I+ DE Q T+V NIY++GD V Sbjct: 292 NYIVVDENQRTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENVTEDIFYNV 351 Query: 340 ELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKE 399 +LTPVAI AGR L++RLF + K +Y+ +P+VIFSHP G+IG+SE+ AI+ YGKE Sbjct: 352 QLTPVAINAGRLLADRLF---LKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQIYGKE 408 Query: 400 NIKVYNSKFTAMYYAMLS----EKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVA 455 N+K+Y SKFT +++++ K T K+VC G +E + GLHI+G ++ EI+QGF VA Sbjct: 409 NVKIYESKFTNLFFSVYDIEPELKEKTYLKLVCVGKDELIKGLHIIGLNADEIVQGFAVA 468 Query: 456 IKMGATKADFDNCVAIHPTSAEELVTMR 483 +KM ATK DFD + IHPT+AEE +T++ Sbjct: 469 LKMNATKKDFDETIPIHPTAAEEFLTLQ 496 >6BZ0-A nrPDB Length = 480 Score = 467 bits (1203), Expect = e-132, Method: Composition-based stats. Identities = 121/467 (25%), Positives = 229/467 (49%), Gaps = 21/467 (4%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK------ALGGTCVNVGCVPKKVMW 73 ++ +D +VIGGG GG +A RAA G K +E + +LGGTC+NVGC+P K + Sbjct: 4 MSQQFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALL 63 Query: 74 YASD-LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 +S V H ++G+ + F+ + ++D V +L G + L+ + Sbjct: 64 DSSHRYEDTVHHLADHGIT------TGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGI 117 Query: 133 DVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-FPENIPGFELGTDSDGFF 191 + + G + VE + T++ ++++A+G + P ++ DS G Sbjct: 118 EWLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGAL 177 Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 E PK++ V+GAG IG+EL V+ LG+E + + L D+ + K+ Sbjct: 178 NFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQ 237 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKL 310 G+++ +K+ E N +K D+LI +GRK++ G+ +E+ GIKL Sbjct: 238 GLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKL 297 Query: 311 NSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYE 370 + +++ T+V +Y++GD+V L A+ G R+ G +++Y+ Sbjct: 298 TERGLVEVNDHCATSVEGVYAIGDLVRGPMLAHKAMEEGVMAVERIHG----HAAQVNYD 353 Query: 371 NVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAG 430 + S+I++HPEA +G++E++A EK G E +K F A+ + + K V Sbjct: 354 TIISIIYTHPEAAWVGLTEEQAKEK-GHE-VKTGQFGFAVNGRALAAGEGAGFVKFVADA 411 Query: 431 PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAE 477 ++++G+H++G ++++I+ +A++ ++ D HPT +E Sbjct: 412 KTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSE 458 >1V59-A nrPDB Length = 478 Score = 466 bits (1199), Expect = e-131, Method: Composition-based stats. Identities = 128/475 (26%), Positives = 230/475 (48%), Gaps = 25/475 (5%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASD 77 T K +D ++IGGG G +A +AA G T VE + LGGTC+NVGC+P K + S Sbjct: 1 TINKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSH 60 Query: 78 LATRVS-HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 L ++ A + G+ N + N F++ +D V +L G + +K KV Sbjct: 61 LFHQMHTEAQKRGIDVN-----GDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYK 115 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHI------LVATGGKAIFPENIP-GFELGTDSDG 189 G F + + V D +HI +VATG + I E S G Sbjct: 116 GNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTG 175 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 L+E PK++ ++G G IG+E+ V+ LGS+ +V + D + Sbjct: 176 ALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLK 235 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSI----DDVDELIWTIGRKSHL-GMGSE 304 K+G++ +K++ ++N + + ++I + D+K+ + + L+ +GR+ ++ G+G+E Sbjct: 236 KQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAE 295 Query: 305 NVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRN 364 +G++++ +++ D+ N+ P+I +GDV L A G L K + Sbjct: 296 KIGLEVDKRGRLVIDDQFNSKFPHIKVVGDVTFGPMLAHKAEEEGIAAVEML----KTGH 351 Query: 365 DKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY 424 ++Y N+PSV++SHPE +G +E++ K + K+ F A A ++ + Sbjct: 352 GHVNYNNIPSVMYSHPEVAWVGKTEEQL--KEAGIDYKIGKFPFAANSRAKTNQDTEGFV 409 Query: 425 KIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 KI+ E+++G HI+G ++ E++ G+A++ GA+ D HPT +E Sbjct: 410 KILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAF 464 >2YQU-A nrPDB Length = 455 Score = 465 bits (1196), Expect = e-131, Method: Composition-based stats. Identities = 122/459 (26%), Positives = 210/459 (45%), Gaps = 22/459 (4%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRV 82 YD LVIG G GG +A RAA G K +VE KALGGTC+ VGC+P K + ++ Sbjct: 2 YDLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYEA 61 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 L + + + P +D V + +K + G ARF Sbjct: 62 K-------KGLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFL 114 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP-GFELGTDSDGFFRLEEQPKKVV 201 + V V + T E A +IL+ATG + P +E S E PK+++ Sbjct: 115 SERKVLV---EETGEELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKRLI 171 Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKI 261 VVG G IG+EL V+H LG+E ++ + +L D + + K+G+ + ++ Sbjct: 172 VVGGGVIGLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKKQGLTIRTGVRV 231 Query: 262 VKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADE 320 V + ++++ + + + D ++ +GR+ + G+ EN G+ + +I DE Sbjct: 232 TAVVPEAKGARVEL---EGGEVLEADRVLVAVGRRPYTEGLSLENAGLSTDERGRIPVDE 288 Query: 321 YQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHP 380 + T VP+IY++GDVV L A G + +DY+ +PSV+++HP Sbjct: 289 HLRTRVPHIYAIGDVVRGPMLAHKASEEGIAAVEHMVRGF----GHVDYQAIPSVVYTHP 344 Query: 381 EAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHI 440 E ++G +E+E K KV ++A A ++ K++ ++++G+H Sbjct: 345 EIAAVGYTEEEL--KAQGIPYKVGKFPYSASGRARAMGETEGFIKVLAHAKTDRILGVHG 402 Query: 441 VGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +G ++L +A+ A+ D HP+ +E L Sbjct: 403 IGARVGDVLAEAALALFFKASAEDLGRAPHAHPSLSEIL 441 >4DNA-A nrPDB Length = 463 Score = 455 bits (1171), Expect = e-128, Method: Composition-based stats. Identities = 155/465 (33%), Positives = 243/465 (52%), Gaps = 17/465 (3%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 + YD VIGGGSGGV S R AA+ G K + E GGTCV GCVPKK+ YAS Sbjct: 1 MSAFDYDLFVIGGGSGGVRSGRLAAALGKKVAIAEEFRYGGTCVIRGCVPKKLYVYASQF 60 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 A A +G F+W + ++ + RL G+Y+K L +++ Sbjct: 61 AEHFEDAAGFGWTVGES------RFDWAKLVAAKEQEIARLEGLYRKGLANAGAEILDTR 114 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK 198 A V++ + +A I++A GG + +PG EL S+ F L P+ Sbjct: 115 AELAGPNTVKLLAS---GKTVTAERIVIAVGGHPSPHDALPGHELCITSNEAFDLPALPE 171 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 +++ G GYI +E A +FHGLG +T L+ RG+ +L +FD+ ++ + ++GI + Sbjct: 172 SILIAGGGYIAVEFANIFHGLGVKTTLIYRGKEILSRFDQDMRRGLHAAMEEKGIRILCE 231 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQII 317 I V + + ++ M + D+++ +GR + G+G E G++ N II Sbjct: 232 DIIQSVSADADGRRVATTMKHGE--IVADQVMLALGRMPNTNGLGLEAAGVRTNELGAII 289 Query: 318 ADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 D + T+ P IY+LGDV +V+LTPVAI + D++ + + +F Sbjct: 290 VDAFSRTSTPGIYALGDVTDRVQLTPVAIHEAMCFIETEYKNNPTSP---DHDLIATAVF 346 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVG 437 S PE G++GI+E+EA K+ + I+VY ++F M + K T K+V + KVVG Sbjct: 347 SQPEIGTVGITEEEAARKF--QEIEVYRAEFRPMKATLSGRKEKTIMKLVVNAADRKVVG 404 Query: 438 LHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482 HI+G + E+ Q G++++ G TK DFD +A+HPT+AEELVTM Sbjct: 405 AHILGHDAGEMAQLLGISLRAGCTKDDFDRTMAVHPTAAEELVTM 449 >2QAE-A nrPDB Length = 468 Score = 450 bits (1157), Expect = e-127, Method: Composition-based stats. Identities = 120/449 (26%), Positives = 209/449 (46%), Gaps = 18/449 (4%) Query: 38 SARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLATRVS-HANEYGLYQNLP 95 ++ +AA G KT VE + LGGTC+NVGC+P K + +A+ L + YGL Sbjct: 17 ASIKAAQLGMKTACVEKRGALGGTCLNVGCIPSKALLHATHLYHDAHANFARYGL----- 71 Query: 96 LDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNT 155 + E +T + + +Q+++ V L G + +K KV G F ++ V D Sbjct: 72 MGGEGVTMDSAKMQQQKERAVKGLTGGVEYLFKKNKVTYYKGEGSFETAHSIRVNGLDGK 131 Query: 156 TEVYSANHILVATGGKAIFPENIPGFE-LGTDSDGFFRLEEQPKKVVVVGAGYIGIELAG 214 E+ ++ATG + +P E + S G L PK +VV+G G IG+EL Sbjct: 132 QEMLETKKTIIATGSEPTELPFLPFDEKVVLSSTGALALPRVPKTMVVIGGGVIGLELGS 191 Query: 215 VFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK-EGINVHKLSKIVKVEKNVETDKL 273 V+ LG+E +V DE + N + K E + +K+V N ++ L Sbjct: 192 VWARLGAEVTVVEFAPRCAPTLDEDVTNALVGALAKNEKMKFMTSTKVVGGTNNGDSVSL 251 Query: 274 KIH-MNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQIIADEYQNTNVPNIYS 331 ++ N + + L+ ++GR+ G +G + + + N + ++ T++P++Y+ Sbjct: 252 EVEGKNGKRETVTCEALLVSVGRRPFTGGLGLDKINVAKNERGFVKIGDHFETSIPDVYA 311 Query: 332 LGDVVGK-VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEK 390 +GDVV K L A G + L G + ++Y +P+VI++ PE S+G SE Sbjct: 312 IGDVVDKGPMLAHKAEDEGVACAEILAG----KPGHVNYGVIPAVIYTMPEVASVGKSED 367 Query: 391 EAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQ 450 E ++ KV F A A K++ ++++G+HIV ++ E++ Sbjct: 368 ELKKE--GVAYKVGKFPFNANSRAKAVSTEDGFVKVLVDKATDRILGVHIVCTTAGELIG 425 Query: 451 GFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +A++ GA+ D HPT +E L Sbjct: 426 EACLAMEYGASSEDVGRTCHAHPTMSEAL 454 >6AON-A nrPDB Length = 478 Score = 450 bits (1157), Expect = e-127, Method: Composition-based stats. Identities = 123/472 (26%), Positives = 223/472 (47%), Gaps = 23/472 (4%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-------ALGGTCVNVGCVPKKVM 72 +K +D +VIG G GG +A RAA G ++A A GGTC NVGC+P K + Sbjct: 4 MSKQFDVVVIGAGPGGYIAAIRAAQLGMSVACIDAWQNGQGGPAPGGTCTNVGCIPSKAL 63 Query: 73 WYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 +S+ + +H + ++ + ++ +++ V + N +K KV Sbjct: 64 LQSSEHYEQANHH-----FAEHGIEVKGVSLKLDTLIGRKNTVVKQNNDGILYLFKKNKV 118 Query: 133 DVVFGWARFNK--DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDS-DG 189 G F DG ++ T A H++VATG A +P E S DG Sbjct: 119 TYFHGKGAFAGQVDGGWSIKVTGTTDADLVAKHVIVATGSSARELPGLPFDEKNILSNDG 178 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 + PKK+ V+GAG IG+E+ V+ LG+E ++ L D+ + + Sbjct: 179 ALNIGAVPKKLGVIGAGVIGLEMGSVWRRLGAEVTILEAMPEFLAAADQQVAKEALKSFA 238 Query: 250 KEGINVHKLSKIVKVEKNVETDKL-KIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVG 307 K+G+++ KI +++ ++ + + ++ VD+LI +IGR + G + +E VG Sbjct: 239 KQGLDIQTGVKIGEIKAAAKSITVPYVDAKGAEQKLVVDKLIVSIGRVPYTGGLNAEAVG 298 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKL 367 +KL+ + DE TN+PN++++GDVV L A G ++ R+ G ++ + Sbjct: 299 LKLDERGFVAVDEDCKTNLPNVWAVGDVVRGPMLAHKAEEEGVAVAERIAG----QHGHV 354 Query: 368 DYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIV 427 ++ VP VI++ PE +G +E++ ++ G+E K + F A A + K++ Sbjct: 355 NFATVPWVIYTSPEIAWVGKTEQQ-LKAEGRE-YKAGSFPFMANGRARALGDTTGFAKVI 412 Query: 428 CAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++V+G+HI+G ++E++ ++ D HPT +E + Sbjct: 413 ADAKTDEVLGVHIIGPMASELISEAVTIMEFRGAAEDIARICHAHPTLSEAV 464 >2EQ6-A nrPDB Length = 464 Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats. Identities = 141/466 (30%), Positives = 225/466 (48%), Gaps = 23/466 (4%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 T K YD +VIG G GG +A RAA G K L VEA +GG C+NVGC+P K + +A++ Sbjct: 2 TPMKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAET 61 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + A +GL LD + RD V +L G L+ V+++ G+ Sbjct: 62 LHHLKVAEGFGLKAKPELD-------LKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGF 114 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEE-QP 197 AR VEV E Y A +++ATG + + + P E DS ++EE P Sbjct: 115 ARLVGPKEVEV-----GGERYGAKSLILATGSEPLELKGFPFGEDVWDSTRALKVEEGLP 169 Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K+++V+G G +G+EL V+ LG+E L+ +L + D + KEGI V Sbjct: 170 KRLLVIGGGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRT 229 Query: 258 LSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHD 314 +K V EK + +++ VD+++ +GRK G+G E G+K++ Sbjct: 230 KTKAVGYEKKKDGLHVRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGLGLEKAGVKVDERG 289 Query: 315 QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS 374 I + T+VP +Y++GD L A+ G + G ++ DY+ VPS Sbjct: 290 FIRVNARMETSVPGVYAIGDAARPPLLAHKAMREGLIAAENAAG----KDSAFDYQ-VPS 344 Query: 375 VIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEK 434 V+++ PE +G++E+EA K +KV A A+ + K+V + Sbjct: 345 VVYTSPEWAGVGLTEEEA--KRAGYKVKVGKFPLAASGRALTLGGAEGMVKVVGDEETDL 402 Query: 435 VVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELV 480 ++G+ IVG + E++ +A++MGAT D V HPT +E L+ Sbjct: 403 LLGVFIVGPQAGELIAEAALALEMGATLTDLALTVHPHPTLSESLM 448 >4JDR-A nrPDB Length = 474 Score = 443 bits (1141), Expect = e-125, Method: Composition-based stats. Identities = 126/469 (26%), Positives = 224/469 (47%), Gaps = 23/469 (4%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYA 75 MST K +V+G G G ++A R A G +T++VE LGG C+NVGC+P K + + Sbjct: 1 MSTEIK-TQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHV 59 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV 135 + + E+G+ P W ++ +++L G + KV VV Sbjct: 60 AKVIEEAKALAEHGIVFGEPKTDIDKIRTW------KEKVINQLTGGLAGMAKGRKVKVV 113 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP-GFELGTDSDGFFRLE 194 G +F +EV+ + T V + ++ ++A G + I IP DS L+ Sbjct: 114 NGLGKFTGANTLEVEGENGKT-VINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELK 172 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 E P++++V+G G IG+E+ V+H LGS+ +V + V+ D+ I T K+ N Sbjct: 173 EVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKF-N 231 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSK---SIDDVDELIWTIGRKSH-LGMGSENVGIKL 310 + +K+ VE + + + M K D ++ IGR + + + G+++ Sbjct: 232 LMLETKVTAVEAKEDG--IYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEV 289 Query: 311 NSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYE 370 + I D+ TNVP+I+++GD+VG+ L + G + + G + + D + Sbjct: 290 DDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHY----FDPK 345 Query: 371 NVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAG 430 +PS+ ++ PE +G++EKEA EK + + + A A+ S+ + K++ Sbjct: 346 VIPSIAYTEPEVAWVGLTEKEAKEK--GISYETATFPWAASGRAIASDCADGMTKLIFDK 403 Query: 431 PNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 + +V+G IVG + E+L G+AI+MG D + HPT E + Sbjct: 404 ESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESV 452 >5X1Y-B nrPDB Length = 554 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 136/464 (29%), Positives = 242/464 (52%), Gaps = 21/464 (4%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 N +YD L+IG G+ +SA +A YGAK ++E +GGTCVN+GCVP K + A ++ Sbjct: 81 NEDNYDLLIIGSGAAAFSSAIKAIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEII 140 Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRL-NGIYQKNLEKEKVDVVFGW 138 +S N + + L + ++D V L N Y +++ D++ G Sbjct: 141 -HLSKDNPF-----IGLQTSAGEVDLASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGE 194 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG--TDSDGFFRLEEQ 196 A+F VEV SA L+ATG P I G E S L++ Sbjct: 195 AKFVDASTVEVNGAK-----LSAKRFLIATGASPSLP-QISGLEKMDYLTSTTLLELKKI 248 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 PK++ V+G+GYIG+EL +FH LGSE L+ R E +L+++D I ++ +++GIN+ Sbjct: 249 PKRLTVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLV 308 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHDQ 315 K + +VE++ E ++ + +N S+ + + D+L+ GRK + + G++ +++ Sbjct: 309 KGATFERVEQSGEIKRVYVTVNGSREVIESDQLLVATGRKPNTDSLNLSAAGVETGKNNE 368 Query: 316 IIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSV 375 I+ +++ T+ IY+ GDV + VA G +++ G N K+D VP+V Sbjct: 369 ILINDFGQTSNEKIYAAGDVTLGPQFVYVAAYEGGIITDNAIGG---LNKKIDLSVVPAV 425 Query: 376 IFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKV 435 F++P ++G++E++A EK ++K A+ A+++ ++ +K+V KV Sbjct: 426 TFTNPTVATVGLTEEQAKEK--GYDVKTSVLPLDAVPRAIVNRETTGVFKLVADAETLKV 483 Query: 436 VGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +G+HIV +++ +++ +A+K G T D +A + T AE L Sbjct: 484 LGVHIVSENAGDVIYAASLAVKFGLTVEDLTETLAPYLTMAEGL 527 >6CMZ-A nrPDB Length = 466 Score = 431 bits (1109), Expect = e-121, Method: Composition-based stats. Identities = 126/463 (27%), Positives = 209/463 (45%), Gaps = 14/463 (3%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 + +H LVIGGG GG +A RA G T+LVE LGGTC+N+GC+P K + + +D Sbjct: 3 AMKNEHTTLLVIGGGPGGYVAAIRAGQLGIPTVLVERDRLGGTCLNIGCIPSKALIHVAD 62 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 A + L + + + +D V RL L+K V V+ G Sbjct: 63 ---AFEQACGHAGEGALGIRVRAPEIDIAKSVAWKDGIVDRLTRGVGALLKKSGVRVLHG 119 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQP 197 AR VEV H+L+ATG + + ++P S P Sbjct: 120 EARVIDGKTVEVVSA-GHAVRIGCEHLLLATGSEPVELPSMPFGGHVVSSTDALSPATLP 178 Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K++VVVGAGYIG+EL V+ LG + +V E VL +D + + D + G+ + Sbjct: 179 KRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERVLPAYDAELVRPVADSLARLGVRLWL 238 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQI 316 K++ ++K+ + ++ D ++ +GR+ + G G E + + N + Sbjct: 239 GHKVLGLDKHGAVRVQA--ADGAEQTLPADRVLVAVGRRPRVDGFGLETLMLDRNGR-AL 295 Query: 317 IADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 D+ T++ N++++GDV G+ L A+A G ++ + G R + +P+V Sbjct: 296 RIDDTCRTSMRNVWAIGDVAGEPMLAHRAMAQGEMVAELIAG----RRRQFMPAAIPAVC 351 Query: 377 FSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVV 436 F+ PE + G S +A G + + + F A AM + + ++V N +V Sbjct: 352 FTDPEIVTAGWSPDDA-HAAGVDCLSA-SFPFAANGRAMTLQATDGFVRVVARRDNHLIV 409 Query: 437 GLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 G VG +E+ F +++MGA D + HPT E L Sbjct: 410 GWQAVGRGVSELAAAFSQSLEMGARLEDIGGTIHAHPTLGEAL 452 >1LVL-A nrPDB Length = 458 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 124/461 (26%), Positives = 209/461 (45%), Gaps = 19/461 (4%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 T L+IGGG GG +A RA G T+LVE +ALGGTC+N+GC+P K + + + Sbjct: 2 QTIQTTLLIIGGGPGGYVAAIRAGQLGIPTVLVEGQALGGTCLNIGCIPSKALIHVA--- 58 Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA 139 + A+ + L + + + +D V RL L+K V VV GWA Sbjct: 59 EQFHQASRFTEPSPLGISVASPRLDIGQSVAWKDGIVDRLTTGVAALLKKHGVKVVHGWA 118 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKK 199 + VEV + H+L+ATG ++ +P S + P+ Sbjct: 119 KVLDGKQVEVDG-----QRIQCEHLLLATGSSSVELPMLPLGGPVISSTEALAPKALPQH 173 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 +VVVG GYIG+EL + LG++ +V E +L +D + + + K GI +H Sbjct: 174 LVVVGGGYIGLELGIAYRKLGAQVSVVEARERILPTYDSELTAPVAESLKKLGIALHLGH 233 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIA 318 + E L + + D ++ +GR+ G E + +K+N I Sbjct: 234 SVEGYE---NGCLLANDGKGGQLRLEADRVLVAVGRRPRTKGFNLECLDLKMNG-AAIAI 289 Query: 319 DEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFS 378 DE T++ N++++GDV G+ L A+A G ++ + G + + + + +V F+ Sbjct: 290 DERCQTSMHNVWAIGDVAGEPMLAHRAMAQGEMVAEIIAG----KARRFEPAAIAAVCFT 345 Query: 379 HPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 PE +G + ++A ++ G + I V F A AM E ++V N ++G Sbjct: 346 DPEVVVVGKTPEQASQQ-GLDCI-VAQFPFAANGRAMSLESKSGFVRVVARRDNHLILGW 403 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 VG + +E+ F +++MGA D + HPT E + Sbjct: 404 QAVGVAVSELSTAFAQSLEMGACLEDVAGTIHAHPTLGEAV 444 >3II4-A nrPDB Length = 466 Score = 409 bits (1052), Expect = e-114, Method: Composition-based stats. Identities = 122/462 (26%), Positives = 202/462 (43%), Gaps = 19/462 (4%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82 HYD +V+G G GG +A RAA G T +VE K GG C+NVGC+P K + ++L Sbjct: 5 HYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVHIF 64 Query: 83 -SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 A +G+ + D + + R A VH L ++K K+ + G+ F Sbjct: 65 TKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFL-------MKKNKITEIHGYGTF 117 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELG---TDSDGFFRLEEQPK 198 + V D TE + ++ ++ATG +PG L + E PK Sbjct: 118 ADANTLLVDLNDGGTESVTFDNAIIATGSSTRL---VPGTSLSANVVTYEEQILSRELPK 174 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 +++ GAG IG+E V G + +V L D + I + K G+ + Sbjct: 175 SIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTA 234 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQII 317 +K+ + + + + ++++ IG ++ G G + G+ L I Sbjct: 235 TKVESIADGGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIG 294 Query: 318 ADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 D+Y TNV +IY++GDV G ++L VA A G + + G E D+ +P F Sbjct: 295 VDDYMRTNVGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLG--DHRMLPRATF 352 Query: 378 SHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVG 437 P S G++E++A + ++ V FTA A K+V + +++G Sbjct: 353 CQPNVASFGLTEQQARNE--GYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLG 410 Query: 438 LHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 H+VG AE+L +A + T ++ V HPT +E L Sbjct: 411 GHLVGHDVAELLPELTLAQRWDLTASELARNVHTHPTMSEAL 452 >4YWO-A nrPDB Length = 462 Score = 385 bits (988), Expect = e-107, Method: Composition-based stats. Identities = 117/457 (25%), Positives = 203/457 (44%), Gaps = 33/457 (7%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHA 85 +IG G+ G A+ +A G K +L+ +GGTCVNVGCVP K M Y +++ + Sbjct: 18 LAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAREV 77 Query: 86 NEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGI-YQKNLEKEKVDVVFGWARFNKD 144 +Y Q++D V + Y+ L V+++ G ARF Sbjct: 78 TGSEVYPPFSS------------FQEKDGLVQEMRKTKYEDLLSYYDVELIQGEARFISP 125 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGT--DSDGFFRLEEQPKKVVV 202 V+V +V A ++ATG + P IPG + + + + + V Sbjct: 126 HAVKVNG-----QVIEAEKFVIATGSSPLIP-RIPGLDKVGFWTNREALSPDRRIDSLAV 179 Query: 203 VGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIV 262 +G + +E A ++ + E ++ R ++ ++ +G+ V + Sbjct: 180 IGGRALALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVK 239 Query: 263 KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQ 322 +V K + K + DE++ GRK ++ +G EN G++LN I D+ Sbjct: 240 EVRKGAGKIVIT-----DKGEVEADEILLATGRKPNVDLGLENAGVRLNERGGIKVDDEL 294 Query: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382 T+ P+IY+ GDV+G L +A G + + ++D VP VIF+ P Sbjct: 295 RTDNPHIYAAGDVLGGKMLEALAGRQGSIATENALTGS---HKRVDENAVPQVIFTQPNL 351 Query: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG 442 +G++E EA K G+ +V +++ A + K+V N ++VG+H VG Sbjct: 352 ARVGLTEAEARAKEGEVEARV--LPMSSVAKAEIINSRLGFVKMVTM--NGRIVGVHAVG 407 Query: 443 DSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 ++ AE++ +AI+ GAT D + V + PT AE L Sbjct: 408 ENVAEMIGEAALAIRFGATVHDLIDTVHMFPTIAESL 444 >1OJT-A nrPDB Length = 482 Score = 380 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 113/457 (24%), Positives = 193/457 (42%), Gaps = 25/457 (5%) Query: 36 VASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNL 94 ++A AA G K +VE K LGG C+NVGC+P K + + + + V H G+ Sbjct: 19 YSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPE 78 Query: 95 PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRD- 153 P + + +D V RL G + KVDV+ G +F ++EV Sbjct: 79 P------ELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAG 132 Query: 154 ---------NTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVG 204 ++ + + ++A G + IP DS G L+E P K++++G Sbjct: 133 DAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIG 192 Query: 205 AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKV 264 G IG+E+ V+ LGS +V + +++ D + N+ +K V V Sbjct: 193 GGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAV 252 Query: 265 EKNVETDKLKIH-MNDSKSIDDVDELIWTIGRKSHLGM-GSENVGIKLNSHDQIIADEYQ 322 E + + N K D ++ GR + + +E G+ + I D+ Sbjct: 253 EPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQM 312 Query: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382 TNVP+IY++GD+VG+ L A+ G + G + D +P V ++ PE Sbjct: 313 RTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHK----AYFDARVIPGVAYTSPEV 368 Query: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG 442 +G +E A K I N + A A+ + K++ +++G IVG Sbjct: 369 AWVGETELSA--KASARKITKANFPWAASGRAIANGCDKPFTKLIFDAETGRIIGGGIVG 426 Query: 443 DSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 + +++ +AI+MG AD + HPT E + Sbjct: 427 PNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESI 463 >5U25-A nrPDB Length = 602 Score = 375 bits (964), Expect = e-104, Method: Composition-based stats. Identities = 113/457 (24%), Positives = 193/457 (42%), Gaps = 25/457 (5%) Query: 36 VASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNL 94 ++A AA G K +VE K LGG C+NVGC+P K + + + + V H G+ Sbjct: 138 YSAAFAAADEGLKVAIVERYKTLGGVCLNVGCIPSKALLHNAAVIDEVRHLAANGIKYPE 197 Query: 95 PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRD- 153 P + + +D V RL G + KVDV+ G +F ++EV Sbjct: 198 P------ELDIDMLRAYKDGVVSRLTGGLAGMAKSRKVDVIQGDGQFLDPHHLEVSLTAG 251 Query: 154 ---------NTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVG 204 ++ + + ++A G + IP DS G L+E P K++++G Sbjct: 252 DAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALALKEVPGKLLIIG 311 Query: 205 AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKV 264 G IG+E+ V+ LGS +V + +++ D + N+ +K V V Sbjct: 312 GGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAV 371 Query: 265 EKNVETDKLKIH-MNDSKSIDDVDELIWTIGRKSHLGM-GSENVGIKLNSHDQIIADEYQ 322 E + + N K D ++ GR + + +E G+ + I D+ Sbjct: 372 EPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAPNGKLISAEKAGVAVTDRGFIEVDKQM 431 Query: 323 NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382 TNVP+IY++GD+VG+ L A+ G + G + D +P V ++ PE Sbjct: 432 RTNVPHIYAIGDIVGQPMLAHKAVHEGHVAAENCAGHK----AYFDARVIPGVAYTSPEV 487 Query: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG 442 +G +E A K I N + A A+ + K++ +++G IVG Sbjct: 488 AWVGETELSA--KASGRKITKANFPWAASGRAIANGCDNGFTKLIFDAETGRIIGGGIVG 545 Query: 443 DSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 + +++ +AI+MG AD + HPT E + Sbjct: 546 PNGGDMIGEVCLAIEMGCDAADIGKTIHPHPTLGESI 582 >1ZK7-A nrPDB Length = 467 Score = 352 bits (903), Expect = 2e-97, Method: Composition-based stats. Identities = 120/461 (26%), Positives = 211/461 (45%), Gaps = 26/461 (5%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHA 85 VIG G +A+A +A GA+ L+E +GGTCVNVGCVP K+M A+ +A + Sbjct: 7 VAVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRES 66 Query: 86 NEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRL-NGIYQKNLEKE-KVDVVFGWARFNK 143 G + T + + ++ A V L + Y+ L + VV G ARF Sbjct: 67 PFDG-----GIAATVPTIDRSKLLAQQQARVDELRHAKYEGILGGNPAITVVHGEARFKD 121 Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGT--DSDGFFRLEEQPKKVV 201 D ++ V+ + V + LVATG P IPG + S + P+++ Sbjct: 122 DQSLTVRLNEGGERVVMFDRCLVATGASPAVPP-IPGLKESPYWTSTEALASDTIPERLA 180 Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKI 261 V+G+ + +ELA F LGS+ ++ R R+ D I +T + EGI V + ++ Sbjct: 181 VIGSSVVALELAQAFARLGSKVTVLARNTLFFRE-DPAIGEAVTAAFRAEGIEVLEHTQA 239 Query: 262 VKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHDQIIADE 320 +V L + + D+L+ GR + + + G+ +N+ I+ D+ Sbjct: 240 SQVAHMDGEFVLTTTHGELR----ADKLLVATGRTPNTRSLALDAAGVTVNAQGAIVIDQ 295 Query: 321 YQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHP 380 T+ PNIY+ GD + + VA AAG + + + G + LD +P+V+F+ P Sbjct: 296 GMRTSNPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGG----DAALDLTAMPAVVFTDP 351 Query: 381 EAGSIGISEKEAIEKYGKENIKVYNSKFT--AMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 + ++G SE EA + I+ + T + A+ + + K+V + +++G+ Sbjct: 352 QVATVGYSEAEA----HHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSHRLIGV 407 Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 V + E++Q +AI+ T + + + + T E L Sbjct: 408 QAVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGL 448 >3IC9-A nrPDB Length = 492 Score = 316 bits (811), Expect = 1e-86, Method: Composition-based stats. Identities = 108/472 (22%), Positives = 202/472 (42%), Gaps = 21/472 (4%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 + + D +IG G+ G+ + R A + K +L+E A G TC VGC+P K++ A+D Sbjct: 3 AMKVINVDVAIIGTGTAGMGAYRAAKKHTDKVVLIEGGAYGTTCARVGCMPSKLLIAAAD 62 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEK-EKVDVVF 136 + S + +G+ + ++ N ++ R G +++E ++ D + Sbjct: 63 ASYHASQTDLFGI------QVDRISVNGKAVMKRIQTERDRFVGFVVESVESFDEQDKIR 116 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGF-ELGTDSDGFFRLEE 195 G+A+F + ++V D+ ++V A I++ATG + +PE + +D F L + Sbjct: 117 GFAKFLDEHTLQV---DDHSQVI-AKRIVIATGSRPNYPEFLAAAGSRLLTNDNLFELND 172 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 255 PK V V G G IG+EL LG + R +V DE ++ + +E Sbjct: 173 LPKSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTFNEEFYFD 232 Query: 256 HKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSHD 314 K I +EK + + + K+ + ++ GRK+++ +G EN I+L+ + Sbjct: 233 AKARVISTIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKN 292 Query: 315 QIIADE-YQNTNVPNIYSLGDVVGKVELTPVAIAAGRKL-SNRLFGPEKFRNDKLDYENV 372 + DE T+V +I+ GD + L A G+ +N P + + Sbjct: 293 SPLFDELTLQTSVDHIFVAGDANNTLTLLHEAADDGKVAGTNAGAYPVIAQGQR---RAP 349 Query: 373 PSVIFSHPEAGSIGISEKEAIEKYGKE---NIKVYNSKFTAMYYAMLSEKSPTRYKIVCA 429 SV+F+ P+ S+G+S ++ + Y + N V F + + K+ + Sbjct: 350 LSVVFTEPQVASVGLSLRQIEDLYADQDAANYVVGQVSFEGQGRSRVMGKNKGLLNVYAD 409 Query: 430 GPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVT 481 + + +G + G ++ I A + T HP E L T Sbjct: 410 RTSGEFLGAEMFGPAAEHIGHLLAWARQQQMTVQAMLTMPFYHPVIEEGLRT 461 >1XDI-A nrPDB Length = 499 Score = 311 bits (796), Expect = 6e-85, Method: Composition-based stats. Identities = 100/466 (21%), Positives = 184/466 (39%), Gaps = 23/466 (4%) Query: 26 YLVIGGGSGGVASARRAASYGA---KTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82 +++GGG G +A AA+ + +++ +GG V CVP K ++ L T + Sbjct: 5 IVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRTEL 64 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 A G + +D + + P+ + + L V V+ G Sbjct: 65 RRAPHLGFH----IDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELI 120 Query: 143 KD------GNVEVQKRDNTTEVYSANHILVATGGKA-IFPENIPGFELGTDSDGFFRLEE 195 ++ D +T + A+ +LVATG I P P E + L+ Sbjct: 121 DSTPGLARHRIKATAADGSTSEHEADVVLVATGASPRILPSAQPDGERILTWRQLYDLDA 180 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 255 P ++VVG+G G E + LG +V + VL D + + + + G+ + Sbjct: 181 LPDHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAERGVRL 240 Query: 256 HKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-GMGSENVGIKLNSHD 314 K ++ V + + + M D ++++ L+ TIG + G+G E VGI+L + Sbjct: 241 FKNARAASVTRTGAG--VLVTMTDGRTVEGSHALM-TIGSVPNTSGLGLERVGIQLGRGN 297 Query: 315 QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS 374 + D T IY+ GD G + L VA GR G V + Sbjct: 298 YLTVDRVSRTLATGIYAAGDCTGLLPLASVAAMQGRIAMYHALGEGVSPIR---LRTVAA 354 Query: 375 VIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEK 434 +F+ PE ++G+ +++ G + A +SE KI C Sbjct: 355 TVFTRPEIAAVGV--PQSVIDAGSVAARTIMLPLRTNARAKMSEMRHGFVKIFCRRSTGV 412 Query: 435 VVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELV 480 V+G +V ++E++ VA++ T + +A++P+ + + Sbjct: 413 VIGGVVVAPIASELILPIAVAVQNRITVNELAQTLAVYPSLSGSIT 458 >3L8K-A nrPDB Length = 466 Score = 308 bits (790), Expect = 3e-84, Method: Composition-based stats. Identities = 109/469 (23%), Positives = 206/469 (43%), Gaps = 26/469 (5%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDL 78 + YD +VIG G G A R A L+ + K LGG C+ GCVP K + Sbjct: 1 MSLKYDVVVIGAGGAGYHGAFRLAKAKYNVLMADPKGELGGNCLYSGCVPSKTVREVIQT 60 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLN-GIYQKNLEK-EKVDVVF 136 A R+++ +PLD + Q R YV L +++N+ + E + Sbjct: 61 AWRLTNIAN----VKIPLDFSTV--------QDRKDYVQELRFKQHKRNMSQYETLTFYK 108 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFF----R 192 G+ + +V V+ + ++++A+G + +PG E SD F Sbjct: 109 GYVKIKDPTHVIVKTDEGKEIEAETRYMIIASGAE-TAKLRLPGVEYCLTSDDIFGYKTS 167 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET-VLRKFDECIQNTITDHYVKE 251 + P+ +V++GAGYIG+E+A +F +G +TH++ + ++ D+ I NT+ +K Sbjct: 168 FRKLPQDMVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLEDQDIVNTLL-SILKL 226 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLN 311 I + VK K+ E + + + SK + ++ GR+ + G+ +G+ + Sbjct: 227 NIKFNSPVTEVKKIKDDEYEVIYSTKDGSKKSIFTNSVVLAAGRRPVIPEGAREIGLSI- 285 Query: 312 SHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYEN 371 S I+ DE TN+PN+++ GD G A+ +N + D +D ++ Sbjct: 286 SKTGIVVDETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNIMA-NGMPVDYVDVKS 344 Query: 372 VPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGP 431 +P I++ P +GI +A K G E ++ A + + K++ Sbjct: 345 IPVTIYTIPSLSYVGILPSKA-RKMGIEIVEA-EYNMEEDVSAQIYGQKEGVLKLIFERG 402 Query: 432 NEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELV 480 + +++G ++G S ++ G+A+ G + HP++ E + Sbjct: 403 SMRLIGAWMIGVHSQYLINELGLAVAYGLNAKQLASFAEQHPSTNEIIS 451 >3Q6J-A nrPDB Length = 523 Score = 306 bits (783), Expect = 2e-83, Method: Composition-based stats. Identities = 110/498 (22%), Positives = 208/498 (41%), Gaps = 55/498 (11%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYASD 77 + + YD + IGGG+ G + + G + L+V+ LGG+C + CVP + SD Sbjct: 39 NDPREYDAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPHHLF---SD 95 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKN--LEKEKVDVV 135 A + A + P E + K+ D + NG + KE++++ Sbjct: 96 CAAELMLARTFSGQYWFPDMTEKVV----GIKEVVDLFRAGRNGPHGIMNFQSKEQLNLE 151 Query: 136 FGW---ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFF- 191 + A+ + VE + V+ A ++++A G ++PG ++ G F Sbjct: 152 YILNCPAKVIDNHTVEAAGK-----VFKAKNLILAVGAGPGT-LDVPG----VNAKGVFD 201 Query: 192 ------RLEEQPKK-VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 L+ +P VVVVG +E F+ G T +++R E + D + + Sbjct: 202 HATLVEELDYEPGSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLIKDNETRAYV 261 Query: 245 TDHYVKEGINVHKLSKIVKVEK--NVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMG 302 D ++G+ + S + ++E+ N + + + + D + +G + Sbjct: 262 LDRMKEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMRIETDFVFLGLGEQPRSAEL 321 Query: 303 SENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKF 362 ++ +G+ L +++ +EY T+VPN+Y++GD++G A +G + + G + Sbjct: 322 AKILGLDLGPKGEVLVNEYLQTSVPNVYAVGDLIGGPMEMFKARKSGCYAARNVMGEKIS 381 Query: 363 RNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKE--------------NIKVYNSKF 408 K N P + +H E +G+ E+EA G E N+ + S Sbjct: 382 YTPK----NYPDFLHTHYEVSFLGMGEEEA-RAAGHEIVTIKMPPDTENGLNVALPASDR 436 Query: 409 TAMY-YAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDN 467 T +Y + + KIV KV+G H VG + + Q V IK G T + + Sbjct: 437 TMLYAFGKGTAHMSGFQKIVIDAKTRKVLGAHHVGYGAKDAFQYLNVLIKQGLTVDELGD 496 Query: 468 C--VAIHPTSAEELVTMR 483 + ++PT +L +R Sbjct: 497 MDELFLNPTHFIQLSRLR 514 >3ICS-A nrPDB Length = 588 Score = 197 bits (502), Expect = 8e-51, Method: Composition-based stats. Identities = 77/350 (22%), Positives = 135/350 (38%), Gaps = 36/350 (10%) Query: 140 RFNKDGNVEVQKRDNTTEVYS--ANHILVATGGKAIFPENIPGFEL-----------GTD 186 + NK+ K T E Y+ + ++++ G K I P IPG E TD Sbjct: 118 KINKEEKTITIKNVTTNETYNEAYDVLILSPGAKPIVPS-IPGIEEAKALFTLRNVPDTD 176 Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD 246 + E++P+ V+G G+IG+E+ G E LV V+ D + + + Sbjct: 177 RIKAYIDEKKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMANQVMPPIDYEMAAYVHE 236 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENV 306 H + + + +E+N +LK S S+ D LI IG + + ++ Sbjct: 237 HMKNHDVELVFEDGVDALEENGAVVRLK-----SGSVIQTDMLILAIGVQPESSL-AKGA 290 Query: 307 GIKLNSHDQIIADEYQNTNVPNIYSLGDVVGK----------VELTPVAIAAGRKLSNRL 356 G+ L I +E T+ P+IY++GD + + L A GR L++ + Sbjct: 291 GLALGVRGTIKVNEKFQTSDPHIYAIGDAIEVKDFVTETETMIPLAWPANRQGRMLADII 350 Query: 357 FGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAML 416 G +V V + G++EK I K +V + + + Sbjct: 351 HGHTDSLYKGTLGTSVAKV--FDLTVATTGLNEK--ILKRLNIPYEVVHVQ-ANSHAGYY 405 Query: 417 SEKSPTRYKIVCAGPNEKVVGLHIVG-DSSAEILQGFGVAIKMGATKADF 465 +P K++ + K+ G +G D + + AIK T D Sbjct: 406 PNATPVLIKLIFNKDSGKIYGAQTLGRDGVDKRMDVIATAIKANLTVLDL 455 >3IWA-A nrPDB Length = 472 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 84/386 (21%), Positives = 155/386 (40%), Gaps = 41/386 (10%) Query: 112 RDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQK-RDNTTEVYSANHILVATGG 170 RD R+N + +E A VE++ R + +++A G Sbjct: 70 RDPEFFRINKDVEALVET------RAHAIDRAAHTVEIENLRTGERRTLKYDKLVLALGS 123 Query: 171 KAIFPENIPGFEL-GTDSDGFFRLEEQPK---------KVVVVGAGYIGIELAGVFHGL- 219 KA P + G +L G E + K V+VG G+IG+E+A + Sbjct: 124 KANRPP-VEGMDLAGVTPVTNLDEAEFVQHAISAGEVSKAVIVGGGFIGLEMAVSLADMW 182 Query: 220 GSETHLVIRGETVLRKFDECIQNTITDH-YVKEGINVHKLSKIVKVEKNVETDKLKIHMN 278 G +T +V + ++ F + + H K + VH K+V++E E K+ + Sbjct: 183 GIDTTVVELADQIMPGFTSKSLSQMLRHDLEKNDVVVHTGEKVVRLE--GENGKVARVIT 240 Query: 279 DSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGD---- 334 D +++ D D +I G + + + + G++L+ II D T+ P+I++ GD Sbjct: 241 DKRTL-DADLVILAAGVSPNTQL-ARDAGLELDPRGAIIVDTRMRTSDPDIFAGGDCVTI 298 Query: 335 ---VVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS--VIFSHPEAGSIGISE 389 V GK P+ A R+ R+ G D V S V A G++ Sbjct: 299 PNLVTGKPGFFPLGSMANRQG--RVIGTNLADGDATFPGAVGSWAVKLFEGSASGAGLTV 356 Query: 390 KEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHI---VGDSSA 446 + A+ + G + + V+ +F ++ EK+ ++V P +V+G+ +GD+ Sbjct: 357 EGAL-REGYDAVNVHVEQFDRAHF--YPEKTIMTLQLVVDRPTRRVLGIQGFSTLGDALT 413 Query: 447 EILQGFGVAIKMGATKADFDNCVAIH 472 + + T D N ++ Sbjct: 414 ARINAVATMLASKPTVEDISNAEVVY 439 Score = 31.8 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 16/123 (13%), Positives = 43/123 (34%), Gaps = 22/123 (17%) Query: 198 KKVVVVGAGYIGIELAGVFHGLG--SETHLVIRGETV--------------------LRK 235 K VVV+GA +G + A F L + ++ + + L+ Sbjct: 4 KHVVVIGAVALGPKAACRFKRLDPEAHVTMIDQASRISYGGCGIPYYVSGEVSNIESLQA 63 Query: 236 FDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR 295 + + + + ++ +++ T +++ + D+L+ +G Sbjct: 64 TPYNVVRDPEFFRINKDVEALVETRAHAIDRAAHTVEIENLRTGERRTLKYDKLVLALGS 123 Query: 296 KSH 298 K++ Sbjct: 124 KAN 126 >2BC1-A nrPDB Length = 490 Score = 187 bits (474), Expect = 1e-47, Method: Composition-based stats. Identities = 74/359 (20%), Positives = 137/359 (38%), Gaps = 46/359 (12%) Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE-------------------- 182 V D V + + ++ ATG + I P I G E Sbjct: 121 DAKTV-TALVDGKNHVETYDKLIFATGSQPILPP-IKGAEIKEGSLEFEATLENLQFVKL 178 Query: 183 LGTDSDGFFRLEEQP-KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRK-FDECI 240 +D +LE + K+V VVGAGYIG+ELA F G E L+ +T L +D + Sbjct: 179 YQNSADVIAKLENKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDL 238 Query: 241 QNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 + + + + GI + + +V N + +K+ N+ DVD +I +G + + Sbjct: 239 TDLMAKNMEEHGIQLAFGETVKEVAGNGKVEKIITDKNE----YDVDMVILAVGFRPNTT 294 Query: 301 MGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV----------VGKVELTPVAIAAGR 350 +G N I L + + ++ Q T++P +Y++GD + L A+ G Sbjct: 295 LG--NGKIDLFRNGAFLVNKRQETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGI 352 Query: 351 KLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTA 410 ++ G + + I+ S G++ ++A + Y Sbjct: 353 VAAHNACGTDLEGIGVQGSNGI--SIYG-LHMVSTGLTLEKAKRLGFDAAVTEYTDNQKP 409 Query: 411 MYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG-DSSAEILQGFGVAIKMGATKADFDNC 468 + + P KIV + +++G + + + + F +AI+ G T Sbjct: 410 EF--IEHGNFPVTIKIVYDKDSRRILGAQMAAREDVSMGIHMFSLAIQEGVTIEKLALT 466 >3CGD-A nrPDB Length = 480 Score = 185 bits (471), Expect = 3e-47, Method: Composition-based stats. Identities = 79/466 (16%), Positives = 161/466 (34%), Gaps = 70/466 (15%) Query: 26 YLVIGGGSGGVASA--RRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 Y++IGG + G+++A A + +E + S Sbjct: 39 YVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEI------------------------YS 74 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLE-KEKVDVVFGWARFN 142 +A LP + + + V Y + + + +V V + Sbjct: 75 YA-----QCGLPYVISGAIASTEKLIAR---NVKTFRDKYGIDAKVRHEVTKVDTEKKIV 126 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPE----NIPGFEL---GTDSDGFFRLEE 195 + + + +S + +L+ATG + + PE ++ G L D++ + E Sbjct: 127 YAEHTKTKDVFE----FSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLE 182 Query: 196 QPK--KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 K V ++G G IG+E+A F LG + ++ R + + +D + I K I Sbjct: 183 TNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHHI 242 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 + + + N + + K D ++ ++G K + E I+ N Sbjct: 243 EILTNENVKAFKGNERVEAV----ETDKGTYKADLVLVSVGVKPNTDF-LEGTNIRTNHK 297 Query: 314 DQIIADEYQNTNVPNIYSLGDVV----------GKVELTPVAIAAGRKLSNRLFGPEKFR 363 I + Y TNV ++Y+ GD + + A GR + + Sbjct: 298 GAIEVNAYMQTNVQDVYAAGDCATHYHVIKEIHDHIPIGTTANKQGRLAGLNMLDKRRAF 357 Query: 364 NDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTR 423 L + F + G++EKEA K K T M P Sbjct: 358 KGTLGTGII---KFMNLTLARTGLNEKEA--KGLHIPYKTVKVDSTNMA-GYYPNAKPLY 411 Query: 424 YKIVCAGPNEKVVGLHIVG-DSSAEILQGFGVAIKMGATKADFDNC 468 K++ ++++G ++G + + + +A+ + D ++ Sbjct: 412 LKLLYRSDTKQLLGGQVIGEEGVDKRIDVIAMALFNKMSIHDLEDV 457 Score = 34.5 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGT 60 D +IGGG+ G+ A G K ++E GT Sbjct: 188 DVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGT 223 >5ER0-A nrPDB Length = 518 Score = 185 bits (469), Expect = 5e-47, Method: Composition-based stats. Identities = 75/396 (18%), Positives = 144/396 (36%), Gaps = 55/396 (13%) Query: 97 DKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTT 156 D + L ++ PE QK A V + + + +++ V V ++ TT Sbjct: 104 DPQGLFYSSPEELQKLGANVQMNHNVLAIDPDQKTVTVE------------DLTNHAQTT 151 Query: 157 EVYSANHILVATGGKAIFPENIPGFE-----LGTDSDGFFRL---EEQPKKVVVVGAGYI 208 E Y + +++ +G I P IPG + L + L ++ K++ V+GAGYI Sbjct: 152 ESY--DKLVMTSGSWPIVP-KIPGIDSDRVKLCKNWAHAQALIEDAKEAKRITVIGAGYI 208 Query: 209 GIELAGVFHGLGSETHLVIRGETVLRK-FDECIQNTITDHYVKEGINVHKLSKIVKVEKN 267 G ELA + G + L+ V+ K FD + I Y G+ + + + Sbjct: 209 GAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHGVQLALGETVESFTDS 268 Query: 268 VETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVP 327 + + K+ + D I IG + + + V + + II D+Y ++ P Sbjct: 269 ATG----LTIKTDKNSYETDLAILCIGFRPNTDLLKGKVDMA--PNGAIITDDYMRSSNP 322 Query: 328 NIYSLGDVVGK----------VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIF 377 +I++ GD + L A+ G + L K + ++ + Sbjct: 323 DIFAAGDSAAVHYNPTHQNAYIPLATNAVRQGILVGKNL---VKPTVKYMGTQSSSGLAL 379 Query: 378 SHPEAGSIGISEKEAIEK-YGKENIKV---YNSKFTAMYYAMLSEKSPTRYKIVCAGPNE 433 S G++ A ++ E + V Y +F P +V Sbjct: 380 YDRTIVSTGLTLAAAKQQGLNAEQVIVEDNYRPEFMPS-------TEPVLMSLVFDPDTH 432 Query: 434 KVVGLHIVG-DSSAEILQGFGVAIKMGATKADFDNC 468 +++G ++ ++ V I+ T D Sbjct: 433 RILGGALMSKYDVSQSANTLSVCIQNENTIDDLAMV 468 >3NTA-A nrPDB Length = 574 Score = 179 bits (454), Expect = 3e-45, Method: Composition-based stats. Identities = 75/355 (21%), Positives = 138/355 (38%), Gaps = 55/355 (15%) Query: 153 DNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQP--------------K 198 D + S + +L++ G I P IPG + L P + Sbjct: 98 DGSEYQESYDTLLLSPGAAPIVPP-IPGVDNPLTH----SLRNIPDMDRILQTIQMNNVE 152 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 VVG G+IG+E+ H LG +T L+ + V+ D + +G+++ Sbjct: 153 HATVVGGGFIGLEMMESLHHLGIKTTLLELADQVMTPVDREMAGFAHQAIRDQGVDLRLG 212 Query: 259 SKIVKVEKNVET-----------------DKLKIHMNDSKSIDDVDELIWTIGRKSHLGM 301 + + +V V+T L + +++ + + + D LI IG + + Sbjct: 213 TALSEVSYQVQTHVASDAAGEDTAHQHIKGHLSLTLSNGE-LLETDLLIMAIGVRPETQL 271 Query: 302 GSENVGIKLNSHDQIIADEYQNTNVPNIYSLGD-------VVGKVELTPVAIAA---GRK 351 + + G+ + I + T+ P IY++GD V G+ L P+A A GR Sbjct: 272 -ARDAGLAIGELGGIKVNAMMQTSDPAIYAVGDAVEEQDFVTGQACLVPLAGPANRQGRM 330 Query: 352 LSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAM 411 ++ +FG E+ R + +F G+ G +EK+ +++ G KVY TA Sbjct: 331 AADNMFGREE-RYQGTQGTAI-CKVF-DLAVGATGKNEKQ-LKQAGIAFEKVYVH--TAS 384 Query: 412 YYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG-DSSAEILQGFGVAIKMGATKADF 465 + + +K++ + G VG D + + VA + G T Sbjct: 385 HASYYPGAEVVSFKLLFDPVKGTIFGAQAVGKDGIDKRIDVMAVAQRAGMTVEQL 439 >3OC4-A nrPDB Length = 452 Score = 175 bits (443), Expect = 5e-44, Method: Composition-based stats. Identities = 69/382 (18%), Positives = 139/382 (36%), Gaps = 53/382 (13%) Query: 114 AYVHRLNGIYQKNLEKEKVDVVFGWARFNKD--GNVEVQKRDNTTEVYSANHILVATGGK 171 +H I ++ L ++K+ ++ D + R + YS + +++ATG Sbjct: 55 NELHEARYITEEELRRQKIQLLLNREVVAMDVENQLIAWTRKEEQQWYSYDKLILATGAS 114 Query: 172 AIFPENIPG--------FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSET 223 F I G ++ + + L E + V V+GAG IG+E + Sbjct: 115 Q-FSTQIRGSQTEKLLKYKFLSGALAAVPLLENSQTVAVIGAGPIGMEAIDFLVKMKKTV 173 Query: 224 HLVIRGETVLRK-FDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS 282 H+ E +L K FD+ + + K+ + H ++ +E+ I + S+ Sbjct: 174 HVFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETANG----IVLETSEQ 229 Query: 283 IDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKV--- 339 D I+ + L + + L+ I D Y T+VPN++++GD + + Sbjct: 230 EISCDSGIFALNLHPQLAYLDKKIQRNLDQT--IAVDAYLQTSVPNVFAIGDCISVMNEP 287 Query: 340 -------ELTPVAIAAGRKLSNRL-------FGPEKFRNDKL-DYENVPSVIFSHPEAGS 384 L A+ G ++N L G + K+ DY S Sbjct: 288 VAETFYAPLVNNAVRTGLVVANNLEEKTHRFIGSLRTMGTKVGDYY-----------LAS 336 Query: 385 IGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGD- 443 G++E E + + + + + K++ ++V+G + Sbjct: 337 TGLTETEGLFFPQTLASIIVRQPAPPLQHG-----TEILGKLIYDKVTQRVLGAQLCSKN 391 Query: 444 SSAEILQGFGVAIKMGATKADF 465 + E + ++I+ G T D Sbjct: 392 NCLEKINTLALSIQTGQTLTDL 413 >4FX9-A nrPDB Length = 453 Score = 171 bits (434), Expect = 5e-43, Method: Composition-based stats. Identities = 75/366 (20%), Positives = 138/366 (37%), Gaps = 42/366 (11%) Query: 124 QKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFEL 183 + ++K +D+ D + + + Y ++++ A G P I G L Sbjct: 69 EVFIKKRGIDLHLNAEVIEVDTGYVRVRENGGEKSYEWDYLVFANGASPQVP-AIEGVNL 127 Query: 184 GTDSDGFFRLEEQPKKVVV--------------VGAGYIGIELAGVFHGLGSETHLVIRG 229 G F + P + + +G GYIGIE+A F G +++RG Sbjct: 128 ----KGVFTADLPPDALAIREYMEKYKVENVVIIGGGYIGIEMAEAFAAQGKNVTMIVRG 183 Query: 230 ETVL-RKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDE 288 E VL R FD+ + + + + K +N+ +K+E +K+ + K + Sbjct: 184 ERVLRRSFDKEVTDILEEKLKKH-VNLRLQEITMKIEGEERVEKVVTDAGEYK----AEL 238 Query: 289 LIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV-------VGK--- 338 +I G K ++ + ++ +G+++ I +E T+V N+Y+ GDV G+ Sbjct: 239 VILATGIKPNIEL-AKQLGVRIGETGAIWTNEKMQTSVENVYAAGDVAETRHVITGRRVW 297 Query: 339 VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGK 398 V L P G + + G E L F E G G++E EA+++ Sbjct: 298 VPLAPAGNKMGYVAGSNIAGKELHFPGVL---GTAVTKFMDVEIGKTGLTEMEALKEGYD 354 Query: 399 ENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKM 458 + YY K V +++G+ +VG + + Sbjct: 355 VRTAFIKASTRPHYY---PGGREIWLKGVVDNETNRLLGVQVVGSDILPRIDTAAAMLMA 411 Query: 459 GATKAD 464 G T D Sbjct: 412 GFTTKD 417 Score = 32.2 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 28/131 (21%), Positives = 51/131 (38%), Gaps = 20/131 (15%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSE--THLVIRGETV-------------LRKFDE 238 E KKVV++G G G+ A L E + E V L D+ Sbjct: 3 ENMKKKVVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVSHAPCGIPYVVEGLSTPDK 62 Query: 239 CIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSH 298 + K GI++H +++++V +T +++ N + + D L++ G Sbjct: 63 LMYYPPEVFIKKRGIDLHLNAEVIEV----DTGYVRVRENGGEKSYEWDYLVFANGASPQ 118 Query: 299 LGMGSENVGIK 309 + E V +K Sbjct: 119 VP-AIEGVNLK 128 >1YQZ-A nrPDB Length = 438 Score = 165 bits (419), Expect = 3e-41, Method: Composition-based stats. Identities = 79/405 (19%), Positives = 152/405 (37%), Gaps = 46/405 (11%) Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKD 144 A Y + + + + L + +F ++ V + + N E++ V V+ Sbjct: 44 ALPYVIGEVVEDRRYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVSVLN-------- 95 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFEL------GTDSDGFFRLEEQPK 198 ++ N S + ++++ G A TD+ F Q Sbjct: 96 ------RKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVD 149 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 KV+VVGAGY+ +E+ + G L+ R + + + D + I D K I Sbjct: 150 KVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLN 209 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIA 318 +I + N T K S ++ D +I +G + E+ IKL+ I Sbjct: 210 EEINAINGNEITFK-------SGKVEHYDMIIEGVGTHPNSKF-IESSNIKLDRKGFIPV 261 Query: 319 DEYQNTNVPNIYSLGDV-------VGKVELTPVAIAAGRKL---SNRLFGPEKFRNDKLD 368 ++ TNVPNIY++GD+ V P+A A R + ++ G + Sbjct: 262 NDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFL 321 Query: 369 YENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVC 428 N+ V F S+G+ E ++++ + ++V A YY SP ++ Sbjct: 322 GNNI--VKFFDYTFASVGVKPNE-LKQFDYKMVEVTQGA-HANYY---PGNSPLHLRVYY 374 Query: 429 AGPNEKVVGLHIVG-DSSAEILQGFGVAIKMGATKADFDNCVAIH 472 N +++ VG + + + + +A+ T + + Sbjct: 375 DTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAY 419 >1NHQ-A nrPDB Length = 447 Score = 164 bits (415), Expect = 9e-41, Method: Composition-based stats. Identities = 72/389 (18%), Positives = 146/389 (37%), Gaps = 49/389 (12%) Query: 109 KQKRDAYVHRLNGIYQKNLEKEKVDVV-FGWARFNKDGNVEVQKRD---NTTEVYSANHI 164 + + V+ + + + +E V+V + +V +D V + + + Sbjct: 48 LEGKVKDVNSVRYMTGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKL 107 Query: 165 LVATGGKAIFPENIPGFELG---TDSDGFFRLEEQPKKV-------VVVGAGYIGIELAG 214 +++ G +IPG +L + ++ + K V VV+G+GYIGIE A Sbjct: 108 IISPGAVPFE-LDIPGKDLDNIYLMRGRQWAIKLKQKTVDPEVNNVVVIGSGYIGIEAAE 166 Query: 215 VFHGLGSETHLVIRGETVLRKF-DECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKL 273 F G + ++ + L + D+ + +T+ I + + + E + K+ Sbjct: 167 AFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIATGETVERYEGDGRVQKV 226 Query: 274 KIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLG 333 K+ D D ++ +G + + ++L+ + I DEY T+ P+++++G Sbjct: 227 VT----DKNAYDADLVVVAVGVRPNTAWLKGT--LELHPNGLIKTDEYMRTSEPDVFAVG 280 Query: 334 DVVG----------KVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAG 383 D + L A GR L P K + +F + Sbjct: 281 DATLIKYNPADTEVNIALATNARKQGRFAVKNLEEPVKPFPGVQGSSGLA--VF-DYKFA 337 Query: 384 SIGISEKEAIEKYGKEN-----IKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGL 438 S GI+E A +K GKE ++ Y F +K +K+V +++G Sbjct: 338 STGINEVMA-QKLGKETKAVTVVEDYLMDFNP-------DKQKAWFKLVYDPETTQILGA 389 Query: 439 HIVG-DSSAEILQGFGVAIKMGATKADFD 466 ++ + +AI+ T D Sbjct: 390 QLMSKADLTANINAISLAIQAKMTIEDLA 418 Score = 36.0 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 24/43 (55%) Query: 11 SLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE 53 +++++ + + + + +VIG G G+ +A A G K +++ Sbjct: 137 AIKLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAKAGKKVTVID 179 >2CDU-A nrPDB Length = 452 Score = 161 bits (407), Expect = 8e-40, Method: Composition-based stats. Identities = 69/358 (19%), Positives = 122/358 (34%), Gaps = 51/358 (14%) Query: 142 NKDGNVEVQKRD---NTTEVYSANHILVATGGKAIFPENIPGFELG--------TDSDGF 190 ++ +D N + + + +++ TG K P IPG + D+ Sbjct: 84 VDPETKTIKVKDLITNEEKTEAYDKLIMTTGSKPTVPP-IPGIDSSRVYLCKNYNDAKKL 142 Query: 191 FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRK-FDECIQNTITDHYV 249 F + K + ++G+GYIG ELA + +L+ E VL K FD+ + + Y Sbjct: 143 FEEAPKAKTITIIGSGYIGAELAEAYSNQNYNVNLIDGHERVLYKYFDKEFTDILAKDYE 202 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIK 309 G+N+ SK+ E+ + I D I IG + + + + Sbjct: 203 AHGVNLVLGSKVAAFEEVDDE---IITKTLDGKEIKSDIAILCIGFRPNTELLKGK--VA 257 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGK----------VELTPVAIAAGRKLSNRL--- 356 + + II DEY +++ +I++ GD + L A+ GR + L Sbjct: 258 MLDNGAIITDEYMHSSNRDIFAAGDSAAVHYNPTNSNAYIPLATNAVRQGRLVGLNLTED 317 Query: 357 ----FGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMY 412 G + KL Y S GI+ A N+KV Y Sbjct: 318 KVKDMGTQSSSGLKL-YGR---------TYVSTGINTALAK----ANNLKVSEVIIADNY 363 Query: 413 YA-MLSEKSPTRYKIVCAGPNEKVVGLHIVG-DSSAEILQGFGVAIKMGATKADFDNC 468 + +V ++G + ++ V I+ T D Sbjct: 364 RPEFMLSTDEVLMSLVYDPKTRVILGGALSSMHDVSQSANVLSVCIQNKNTIDDLAMV 421 Score = 35.6 bits (81), Expect = 0.051, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 25/54 (46%) Query: 246 DHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 + G NV ++ V+ +T K+K + + + + D+LI T G K + Sbjct: 66 EELSNLGANVQMRHQVTNVDPETKTIKVKDLITNEEKTEAYDKLIMTTGSKPTV 119 >1Q1R-A nrPDB Length = 431 Score = 147 bits (372), Expect = 9e-36, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 102/257 (39%), Gaps = 32/257 (12%) Query: 156 TEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK----------KVVVVGA 205 + +++ATGG+ G ++ + R E + ++VV+G Sbjct: 98 GRALDYDRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIADNRLVVIGG 157 Query: 206 GYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE-GINVHKLSKIVKV 264 GYIG+E+A L+ VL + + +H +E G+++ +++ Sbjct: 158 GYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRTGTQVCGF 217 Query: 265 EKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNT 324 E + + K+ + + + D +I IG + + + G++++ + I+ +E+ T Sbjct: 218 EMSTDQQKVTAVLCEDGTRLPADLVIAGIGLIPNCEL-ASAAGLQVD--NGIVINEHMQT 274 Query: 325 NVPNIYSLGDVVG----------KVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPS 374 + P I ++GD ++E P A+ RK++ L G P Sbjct: 275 SDPLIMAVGDCARFHSQLYDRWVRIESVPNALEQARKIAAILCGKVPRDEAA------PW 328 Query: 375 VIFSHPEAG--SIGISE 389 E G +G+SE Sbjct: 329 FWSDQYEIGLKMVGLSE 345 Score = 36.0 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 19/118 (16%), Positives = 44/118 (37%), Gaps = 24/118 (20%) Query: 198 KKVVVVGAGYIGIELAGVFHGLG--------SETHLVIRGETVLRKFDECIQNTIT---- 245 VV+VG G G+E+A G + ++ + + T Sbjct: 5 DNVVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVI--PHHLPPLSKAYLAGKATAESL 62 Query: 246 -----DHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSH 298 D Y + I + +++ + + D+ ++ ++D +++ D D L+ G + Sbjct: 63 YLRTPDAYAAQNIQLLGGTQVTAINR----DRQQVILSDGRAL-DYDRLVLATGGRPR 115 Score = 27.9 bits (61), Expect = 8.8, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKA 56 +VIGGG G+ A A L++ A Sbjct: 152 LVVIGGGYIGLEVAATAIKANMHVTLLDTAA 182 >2YVG-A nrPDB Length = 408 Score = 133 bits (334), Expect = 2e-31, Method: Composition-based stats. Identities = 54/290 (18%), Positives = 103/290 (35%), Gaps = 54/290 (18%) Query: 91 YQNLPLDKEHLTFNWPE---FKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNV 147 Y PL K+ + E KR V L G+ ++ + + V R Sbjct: 46 YDRPPLSKDFMAHGDAEKIRLDCKRAPEVEWLLGVTAQSFDPQAHTVALSDGR------- 98 Query: 148 EVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKK-------- 199 +++ATG P +P + T R E ++ Sbjct: 99 ----------TLPYGTLVLATGAA---PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQ 145 Query: 200 --VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDHYVKEGINVH 256 +++VG G IG+ELA G LV ++ R + + + ++ +G+++ Sbjct: 146 SRLLIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAAPATLADFVARYHAAQGVDLR 205 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQI 316 E++V + + D + D ++ IG ++ + + G+ + I Sbjct: 206 -------FERSVTGSVDGVVLLDDGTRIAADMVVVGIGVLANDAL-ARAAGLACDD--GI 255 Query: 317 IADEYQNTNVPNIYSLGDVVG----------KVELTPVAIAAGRKLSNRL 356 D Y T P++Y+LGDV ++E A G ++ L Sbjct: 256 FVDAYGRTTCPDVYALGDVTRQRNPLSGRFERIETWSNAQNQGIAVARHL 305 Score = 29.9 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 16/105 (15%), Positives = 27/105 (25%), Gaps = 6/105 (5%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD-ECIQNTITDHYVKEGINVHKL 258 VVV+GAG + G + + + G+ R +D + H E I + Sbjct: 10 VVVLGAGLASVSFVAELRQAGYQGLITVVGDEAERPYDRPPLSKDFMAHGDAEKIRLDCK 69 Query: 259 SKIV-----KVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSH 298 V + L+ G Sbjct: 70 RAPEVEWLLGVTAQSFDPQAHTVALSDGRTLPYGTLVLATGAAPR 114 >3AB1-A nrPDB Length = 360 Score = 128 bits (321), Expect = 7e-30, Method: Composition-based stats. Identities = 69/355 (19%), Positives = 130/355 (36%), Gaps = 57/355 (16%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVS 83 D +IGGG G+ +A + ++E+ LGG LA Sbjct: 16 DLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGG-----------------QLAALYP 58 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 + Y + + L + ++ + V + E V Sbjct: 59 EKHIYDVAGFPEVPAIDLVESLWAQAERYNPDV----------VLNETVTKY----TKLD 104 Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP---GFELGTDSDGFFRLEEQ---- 196 DG E + NT VY + +L+A G A P +P + T S ++ ++ Sbjct: 105 DGTFETRT--NTGNVYRSRAVLIAAGLGAFEPRKLPQLGNIDHLTGSSVYYAVKSVEDFK 162 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 K+VV+VG G ++ + LV RG + + + I+V+ Sbjct: 163 GKRVVIVGGGDSALDWTVGLIKNAASVTLVHRGHEF--QGHGKTAHEVERARANGTIDVY 220 Query: 257 KLSKIVKVEK-NVETDKLKIHMNDS-KSIDDVDELIWTIGRKSHLG-MGSENVGIKLNSH 313 +++ +E+ N ++ + +D K + D L+ IG KS+LG + ++ + N Sbjct: 221 LETEVASIEESNGVLTRVHLRSSDGSKWTVEADRLLILIGFKSNLGPLARWDLELYEN-- 278 Query: 314 DQIIADEYQNTNVPNIYSLGDVVGKV--------ELTPVAIAAGRKLSNRLFGPE 360 ++ D + T+V +Y+ GD+ L+ +A LS G + Sbjct: 279 -ALVVDSHMKTSVDGLYAAGDIAYYPGKLKIIQTGLSEATMAVRHSLSYIKPGEK 332 >4GCM-A nrPDB Length = 312 Score = 119 bits (298), Expect = 3e-27, Method: Composition-based stats. Identities = 55/331 (16%), Positives = 111/331 (33%), Gaps = 61/331 (18%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 +D +IG G G+ +A A+ KT+++E GG N Sbjct: 2 MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMAN--------------- 46 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 V + + + L + +K +G Sbjct: 47 TEEVENFPGFEMITGPDLSTKMFEHA-----------------------KKFGAVYQYGD 83 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG--------FELGTDSDGF 190 + +D E + + + +A +++ATG + +PG DG Sbjct: 84 IKSVEDKG-EYKVINFGNKELTAKAVIIATGAE-YKKIGVPGEQELGGRGVSYCAVCDGA 141 Query: 191 FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 F + K++ V+G G +E + +V R + + + + Sbjct: 142 FF---KNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDEL-----RAQRILQDRAFKN 193 Query: 251 EGINVHKLSKIVKV-EKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHLGMGSENVG 307 + I+ + + EK+ + + + + S+ + D + IG K +++G Sbjct: 194 DKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTA-PFKDLG 252 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDVVGK 338 I N I+ + T+VP I++ GDV K Sbjct: 253 I-TNDVGYIVTKDDMTTSVPGIFAAGDVRDK 282 >5UWY-A nrPDB Length = 308 Score = 119 bits (298), Expect = 3e-27, Method: Composition-based stats. Identities = 63/326 (19%), Positives = 118/326 (36%), Gaps = 67/326 (20%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 YD L+IG G G+ +A AA ++E A GG Sbjct: 5 YDTLIIGSGPAGMTAALYAARSNLSVAIIEQGAPGG-----------------------Q 41 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAY-VHRLNGIYQKNLEKEKVDVVFGWARFN 142 N + + D + + + + V + GI +K++ F Sbjct: 42 MNNTFDIENYPGYDHISGPELAMKMYEPLEKFNVENIYGIV------QKIE------NFG 89 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDS--------DGFFRLE 194 V + Y A +++ATG K +PG E T DG F + Sbjct: 90 DYKCVLTEDA-----SYEAKTVIIATGAKYRV-LGVPGEEYYTSRGVSYCAVCDGAFFRD 143 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDH-YVKEGI 253 + ++VVG G +E A + +V R + + Q + D + + + Sbjct: 144 ---QDLLVVGGGDSAVEEAIYLTQFAKKVTVVHRRDQL------RAQKILQDRAFANDKV 194 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDE----LIWTIGRKSHLGMGSENVGIK 309 + S + +++ N + + + K+ D + +G GM +++ I Sbjct: 195 DFIWDSVVKEIQGNDIKVS-NVLIENVKTGQVTDHAFGGVFIYVGMNPVTGM-VKDLEI- 251 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDV 335 +S II D++ T++P I+++GDV Sbjct: 252 TDSEGWIITDDHMRTSIPGIFAIGDV 277 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 15/34 (44%) Query: 22 KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 + D LV+GGG V A + K +V + Sbjct: 142 RDQDLLVVGGGDSAVEEAIYLTQFAKKVTVVHRR 175 >3LXD-A nrPDB Length = 415 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 40/202 (19%), Positives = 74/202 (36%), Gaps = 18/202 (8%) Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAI----FPENIPGFELGTDSDGF----FRLEE 195 V++ ++ ATGG ++ G + L+ Sbjct: 95 AHTVKL----GDGSAIEYGKLIWATGGDPRRLSCVGADLAGVHAVRTKEDADRLMAELDA 150 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDHYVKEGIN 254 K VV+G GYIG+E A V G L+ VL R E + + G++ Sbjct: 151 GAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVD 210 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHD 314 + + + +E + K+ S+ D +I IG +G + G + Sbjct: 211 LRTGAAMDCIE--GDGTKVTGVRMQDGSVIPADIVIVGIGIVPCVG-ALISAGAS--GGN 265 Query: 315 QIIADEYQNTNVPNIYSLGDVV 336 + DE+ T++ ++Y++GD Sbjct: 266 GVDVDEFCRTSLTDVYAIGDCA 287 Score = 29.9 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 16/28 (57%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEA 54 +VIGGG G+ +A +G L+EA Sbjct: 156 VVIGGGYIGLEAAAVLTKFGVNVTLLEA 183 >3FG2-P nrPDB Length = 404 Score = 117 bits (294), Expect = 1e-26, Method: Composition-based stats. Identities = 52/261 (19%), Positives = 101/261 (38%), Gaps = 25/261 (9%) Query: 124 QKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPE----NIP 179 +K + + ++++ ++ T H+++ATG + + ++P Sbjct: 64 EKFFQDQAIELISDRMVSIDREGRKLLLASGTA--IEYGHLVLATGARNRMLDVPNASLP 121 Query: 180 GFELGTDSDGFFRLEE-QP--KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RK 235 D L + P K VVV+GAG+IG+E A G E +V V+ R Sbjct: 122 DVLYLRTLDESEVLRQRMPDKKHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARV 181 Query: 236 FDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR 295 I + D + GI +H + ++ E D++ + + D ++ +G Sbjct: 182 VTPEISSYFHDRHSGAGIRMHYGVRATEIA--AEGDRVTGVVLSDGNTLPCDLVVVGVGV 239 Query: 296 KSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDV----------VGKVELTPVA 345 ++ + + L + II D+ T+ P+I ++GD +VE A Sbjct: 240 IPNVEIAAAA---GLPTAAGIIVDQQLLTSDPHISAIGDCALFESVRFGETMRVESVQNA 296 Query: 346 IAAGRKLSNRLFGPEKFRNDK 366 R ++ RL G K + Sbjct: 297 TDQARCVAARLTGDAKPYDGY 317 Score = 28.3 bits (62), Expect = 8.2, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 15/28 (53%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVE 53 +VIG G G+ A A + G + +VE Sbjct: 145 VVVIGAGFIGLEFAATARAKGLEVDVVE 172 >5MJK-A nrPDB Length = 327 Score = 114 bits (286), Expect = 9e-26, Method: Composition-based stats. Identities = 64/328 (19%), Positives = 117/328 (35%), Gaps = 61/328 (18%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 K YD ++IG G G+ +A A KTLL+E GG M +++ Sbjct: 20 MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGVPGG-----------QMNNTAEI 68 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + Y L + LE V+ +G+ Sbjct: 69 ----ENYPGYETIMGPELSMKMAEP-----------------------LEGLGVENAYGF 101 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE--------LGTDSDGF 190 +D + +K + + I++ATG IPG E DG Sbjct: 102 VTGIEDHG-DYKKIITEDDEFITKSIIIATGAN-HRKLEIPGEEEYGARGVSYCAVCDGA 159 Query: 191 FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 F ++ ++V+G G +E A G ++ R + LR + I + + Sbjct: 160 FFRNQE---ILVIGGGDSAVEEALYLTRFGQSVTIMHRRDK-LRA--QEIIQ--QRAFKE 211 Query: 251 EGINVHKLSKIVKVEKNVETDKLKIHMN---DSKSIDDVDELIWTIGRKSHLGMGSENVG 307 E IN S ++++ + + + ++ N + + +G ++G Sbjct: 212 EKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGLDPVAEF-VSDLG 270 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDV 335 I + II D++ TN+P I+++GDV Sbjct: 271 I-TDEAGWIITDDHMRTNIPGIFAVGDV 297 >5JCN-A nrPDB Length = 451 Score = 111 bits (279), Expect = 5e-25, Method: Composition-based stats. Identities = 60/338 (17%), Positives = 118/338 (34%), Gaps = 55/338 (16%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKT---LLVEAKALGGTCVNVGCVPKKVMWYASD 77 KH+ Y+++GGG +AR A G K ++ +A+ P + + Sbjct: 20 EKHFKYVILGGGVAAGYAAREFAKQGVKPGELAIISKEAVA---------PYERPALSKG 70 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 + A G + + E L W ++ ++++ Sbjct: 71 YLFPQNAARLPGFHVCVGSGGERLLPEW---------------------YSEKGIELILS 109 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQ- 196 K ++ +++ATG I + G + G DS+ L E Sbjct: 110 T-EIVKADLASKTLTSAVGATFTYEILIIATGSSVIKLSDF-GTQ-GADSNNILYLREVD 166 Query: 197 -------------PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRK-FDECIQN 242 K V+VG GYIG+EL+ + +V + + F I Sbjct: 167 DADKLVAAIQAKKGGKAVIVGGGYIGLELSAALKINDFDVTMVFPEPWCMPRLFTADIAA 226 Query: 243 TITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMG 302 +Y +G+ + K + V + + D +++ + S+ + D ++ +G + + Sbjct: 227 FYESYYTNKGVKIVKGTVAVGFDADANGDVTAVNLKNG-SVLEADIVVVGVGGRPLTTLF 285 Query: 303 SENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVE 340 V I D + T+VP +Y++GDV Sbjct: 286 KGQVA---EEKGGIKTDAFFETSVPGVYAVGDVATFPM 320 >5UTH-A nrPDB Length = 319 Score = 110 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 63/332 (18%), Positives = 110/332 (33%), Gaps = 60/332 (18%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYAS 76 MST+ +D ++IG G G +A AA K L+ E GG A Sbjct: 9 MSTSQTVHDVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGG---------------AL 53 Query: 77 DLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVF 136 T V + + P + + L +L E VD V Sbjct: 54 MTTTEVENYPGFREGITGPELMDQMRE-------------QALRFG--ADLRMEDVDAVQ 98 Query: 137 GWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE--------LGTDSD 188 V V E + A +++A G A +PG E D Sbjct: 99 LEGPV---KTVVV-----GDETHQARAVILAMGAAARH-LGVPGEEALTGMGVSTCATCD 149 Query: 189 GFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHY 248 GFF + + +VVVG G +E A L+ R + + + Sbjct: 150 GFFFRD---QDIVVVGGGDSAMEEATFLTRFARSVTLIHRRDEF-----RASKIMLERAR 201 Query: 249 VKEGINVHKLSKIVKVEKNVETDKLKI--HMNDSKSIDDVDELIWTIGRKSHLGMGSENV 306 E I ++I ++E + + +++ + +S DV + IG + Sbjct: 202 ANEKITFLTNTEITQIEGDPKVTGVRLRDTVTGEESKLDVTGVFVAIGHDPRSELVRGQ- 260 Query: 307 GIKLNSHDQIIADEYQN-TNVPNIYSLGDVVG 337 ++L+ + T++ +++ GD+V Sbjct: 261 -VELDDEGYVKVQGRTTYTSLDGVFAAGDLVD 291 >2A87-A nrPDB Length = 335 Score = 109 bits (274), Expect = 2e-24, Method: Composition-based stats. Identities = 65/363 (17%), Positives = 118/363 (32%), Gaps = 68/363 (18%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSH 84 D +VIG G G +A AA L+ E + GG + +D V + Sbjct: 16 DVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGG-----------ALMTTTD----VEN 60 Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKD 144 + P + + L +L E V+ V Sbjct: 61 YPGFRNGITGPELMDEMRE-------------QALRFG--ADLRMEDVESVSLHGPLKS- 104 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFEL--------GTDSDGFFRLEEQ 196 V D + + A +++A G A + +PG + DGFF + Sbjct: 105 ----VVTADG--QTHRARAVILAMGAAARY-LQVPGEQELLGRGVSSCATCDGFFFRD-- 155 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 + + V+G G +E A LV R + + + + I Sbjct: 156 -QDIAVIGGGDSAMEEATFLTRFARSVTLVHRRDEF-----RASKIMLDRARNNDKIRFL 209 Query: 257 KLSKIVKVEKNVETDKLKI--HMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHD 314 +V V+ + L++ +++ V + IG + G+ E I ++ Sbjct: 210 TNHTVVAVDGDTTVTGLRVRDTNTGAETTLPVTGVFVAIGHEPRSGLVREA--IDVDPDG 267 Query: 315 QIIA-DEYQNTNVPNIYSLGDVVGKVELTPV---------AIAAGRKLSNRLFGPEKFRN 364 ++ +T++P +++ GD+V + V AI A R L+ E Sbjct: 268 YVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSGCAAAIDAERWLAEHAATGEADST 327 Query: 365 DKL 367 D L Sbjct: 328 DAL 330 >1XHC-A nrPDB Length = 367 Score = 108 bits (271), Expect = 5e-24, Method: Composition-based stats. Identities = 78/392 (19%), Positives = 136/392 (34%), Gaps = 78/392 (19%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVP--KKVMWYASDLATRVS 83 +++G G GG A++ + + +++ + VP K M S Sbjct: 11 VVIVGNGPGGFELAKQLSQ-TYEVTVIDKEP----------VPYYSKPML--SHYIA--- 54 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG-WARFN 142 G L + +W K +++ A+ Sbjct: 55 -----GFIPRNRLFP--YSLDW---------------------YRKRGIEIRLAEEAKLI 86 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVV 202 G V + +++ATG +A P I G E F + + + Sbjct: 87 DRGRKVVITEKGE---VPYDTLVLATGARAREP-QIKGKEYLLTLRTIFDADRIKESIEN 142 Query: 203 VG------AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 G G+IG+ELAG G L+ RG L DE + N I D + G+ Sbjct: 143 SGEAIIIGGGFIGLELAGNLAEAGYHVKLIHRGAMFL-GLDEELSNMIKDMLEETGVKFF 201 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQI 316 S++ +E N E + K I IG ++ + + GI I Sbjct: 202 LNSEL--LEANEEGVLTNSGFIEGKVK------ICAIGIVPNVDL-ARRSGIHTGR--GI 250 Query: 317 IADEYQNTNVPNIYSLGDVV---GKVELTPV-AIAAGRKLSNRLFGPEKFRNDKLDYENV 372 + D+ T+ ++Y++GD G + T A+ R L++ L G + N K Sbjct: 251 LIDDNFRTSAKDVYAIGDCAEYSGIIAGTAKAAMEQARVLADILKGEPRRYNFKFRSTV- 309 Query: 373 PSVIFSHPEAGSIGISEKEAIEKYGKENIKVY 404 F + IG ++ E K+ ++N KV+ Sbjct: 310 --FKFGKLQIAIIGNTKGEG--KWIEDNTKVF 337 Score = 36.8 bits (84), Expect = 0.021, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 38/117 (32%), Gaps = 22/117 (18%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV---LRKFDECIQNTI---------TD 246 KVV+VG G G ELA E ++ + I I D Sbjct: 10 KVVIVGNGPGGFELAKQLSQT-YEVTVIDKEPVPYYSKPMLSHYIAGFIPRNRLFPYSLD 68 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIG---RKSHLG 300 Y K GI + + +++ K+ I K D L+ G R+ + Sbjct: 69 WYRKRGIEIRLAEEAKLIDR---GRKVVIT---EKGEVPYDTLVLATGARAREPQIK 119 >4ZN0-A nrPDB Length = 311 Score = 108 bits (271), Expect = 5e-24, Method: Composition-based stats. Identities = 59/353 (16%), Positives = 115/353 (32%), Gaps = 63/353 (17%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S YD ++IGGG G+ + A YG TL++E + G Sbjct: 2 SHMASMYDLIIIGGGPAGLTAGIYAVRYGLDTLILERNEISG---------------QIS 46 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 +A V + + L L + T V I + Sbjct: 47 MADIVENYPGFPSISGLELMERFRTH---------AQEVGVKTTITEVL----------- 86 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFF-RLEEQ 196 +G ++ D+ A +++ATG +PG + + + + Sbjct: 87 --SVRSEGTKKIITTDSGD--LEAKAVIIATGANPKH-LGVPGEKELISKGVSYCAICDG 141 Query: 197 P----KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE- 251 P K V VVG G + A + + +LV R + + + D Sbjct: 142 PFFRNKIVAVVGGGNSAVTDALFLSKVAQKVYLVHRRDHL------KAARVLQDRVDGTP 195 Query: 252 GINVHKLSKIVKV----EKNVETDKLKIHMNDSKSIDD--VDELIWTIGRKSHLGMGSEN 305 I + S ++++ E + +K+ + +S+ + + + +G + Sbjct: 196 NIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELSTNGVFIYVGIHPNTEF---- 251 Query: 306 VGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPV-AIAAGRKLSNRLF 357 V ++ + I D + T+ IY+ GD V A+ G + + Sbjct: 252 VDVEKDEGGFIKTDRWMETSEKGIYAAGDCRDTPIWQLVTAVRDGAIAATAAY 304 >2Q7V-A nrPDB Length = 325 Score = 107 bits (268), Expect = 1e-23, Method: Composition-based stats. Identities = 59/325 (18%), Positives = 106/325 (32%), Gaps = 55/325 (16%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82 YD ++IGGG G+ +A TL++E GG +A Sbjct: 8 DYDVVIIGGGPAGLTAAIYTGRAQLSTLILEKGMPGG-----------------QIAWS- 49 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 ++ +PE + R++ +K K ++D V G Sbjct: 50 --------------EEVENFPGFPEPIAGME-LAQRMHQQAEKFGAKVEMDEVQGVQHDA 94 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG--------FELGTDSDGFFRLE 194 R E Y A +++ATG IPG DGFF Sbjct: 95 TSHPYPFTVRGYNGE-YRAKAVILATGADPR-KLGIPGEDNFWGKGVSTCATCDGFF--- 149 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 + KKVVV+G G +E E ++ R +T+ + + Sbjct: 150 YKGKKVVVIGGGDAAVEEGMFLTKFADEVTVIHRRDTLRANKVAQ-----ARAFANPKMK 204 Query: 255 VHKLSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNS 312 + + +++ +K+ S D + IG + + V ++ + Sbjct: 205 FIWDTAVEEIQGADSVSGVKLRNLKTGEVSELATDGVFIFIGHVPNTAFVKDTVSLRDD- 263 Query: 313 HDQIIADEYQNTNVPNIYSLGDVVG 337 + + TN+P +++ GDV Sbjct: 264 -GYVDVRDEIYTNIPMLFAAGDVSD 287 >3F8P-A nrPDB Length = 323 Score = 105 bits (263), Expect = 3e-23, Method: Composition-based stats. Identities = 53/333 (15%), Positives = 118/333 (35%), Gaps = 52/333 (15%) Query: 11 SLQIRTMSTNT-KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPK 69 SL RT S + +D +++G G +A +A Y KTL++ + GG Sbjct: 2 SLLPRTTSVKPGEKFDVIIVGLGPAAYGAALYSARYMLKTLVI-GETPGG---------- 50 Query: 70 KVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEK 129 E G+ + E + + + ++ + Y+ + Sbjct: 51 --------------QLTEAGIVDDYLGLIEIQASD---MIKVFNKHIEK----YEVPVLL 89 Query: 130 EKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI---FPENIPGFELGTD 186 + V+ + + V+ +++ + A+ +++ G K P G Sbjct: 90 DIVEKIENRG---DEFVVKTKRKGE----FKADSVILGIGVKRRKLGVPGEQEFAGRGIS 142 Query: 187 SDGFFRLEEQPKKVV-VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTIT 245 +VV V+G G +E A + ++ +L+ R +T + + Sbjct: 143 YCSVCDAPLFKNRVVAVIGGGDSALEGAEILSSYSTKVYLIHRRDTF-----KAQPIYVE 197 Query: 246 DHYVKEGINVHKLSKIVKVEKNVETDKLKIH--MNDSKSIDDVDELIWTIGRKSHLGMGS 303 K + S + +++ + ++ + +V+ + IG Sbjct: 198 TVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNVNGVFIEIGFDPPTDFAK 257 Query: 304 ENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVV 336 N GI+ +++ I DE+ T+VP +++ GD Sbjct: 258 SN-GIETDTNGYIKVDEWMRTSVPGVFAAGDCT 289 >2V3B-A nrPDB Length = 384 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 61/305 (20%), Positives = 113/305 (37%), Gaps = 41/305 (13%) Query: 155 TTEVYSANHILVATGGKAI-FP------ENIPGFELGTDSDGFFRLEEQPKKVVVVGAGY 207 E +++A G + I P + + D F + ++V+++GAG Sbjct: 96 GEEEVRYRDLVLAWGAEPIRVPVEGDAQDALYPINDLEDYARFRQAAAGKRRVLLLGAGL 155 Query: 208 IGIELAGVFHGLGSETHLVIRGETVLRKF-DECIQNTITDHYVKEGINVHKLSKIVKVEK 266 IG E A G + +V E V+ + G+ H + ++K Sbjct: 156 IGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFHLGPVLASLKK 215 Query: 267 NVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNV 326 E L+ H++D + + D ++ +G + + G+ +N I+ D T+ Sbjct: 216 AGEG--LEAHLSDGE-VIPCDLVVSAVGLRPRTELAF-AAGLAVNR--GIVVDRSLRTSH 269 Query: 327 PNIYSLGDV--VGKVELTPVA--IAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEA 382 NIY+LGD V + L V +A R L+ L G ++ Y +P + + Sbjct: 270 ANIYALGDCAEVDGLNLLYVMPLMACARALAQTLAGN----PSQVAYGPMPVTVKTP--- 322 Query: 383 GSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVG 442 + + V + M L E S T K++C +V+G + G Sbjct: 323 -ACPL---------------VVSPPPRGMDGQWLVEGSGTDLKVLCRDTAGRVIGYALTG 366 Query: 443 DSSAE 447 + E Sbjct: 367 AAVNE 371 >6BWT-A nrPDB Length = 319 Score = 104 bits (259), Expect = 1e-22, Method: Composition-based stats. Identities = 56/332 (16%), Positives = 115/332 (34%), Gaps = 61/332 (18%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRV 82 H+ +++G G G +A AA K +++ GG + +D+ Sbjct: 7 HHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGG-----------QLTTTTDVY--- 52 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 N P + + + PE +K R + + VD+ + Sbjct: 53 ----------NWPGEPDGIM--GPELMEKLQKQAERFDTQIVYD-TINAVDLQNKPFKLV 99 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIF-------PENIPGFELGTDSDGFFRLEE 195 E Y+ + +++ATG A + G DGFF Sbjct: 100 -----------GEVEQYTCDTLIIATGATAKYLGLESEEKFMGKGVSACATCDGFF---Y 145 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 255 + K V VVG G +E A + L+ R +T+ + ++ + + + + IN+ Sbjct: 146 KNKDVAVVGGGNTAVEEALFLSNIAKSVTLIHRRDTL--RSEKILIDKLMEKAQHGNINI 203 Query: 256 HKLSKIVKVEKNVETD---KLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNS 312 + + +V + ++K + +S V + IG + + + + + Sbjct: 204 IWNTTLEEVLGDDMGVNALRIKNIKTNEESQMGVAGVFIAIGHTPNTSIFAGQLEM---E 260 Query: 313 HDQIIA-----DEYQNTNVPNIYSLGDVVGKV 339 + I + TN+ +++ GDV V Sbjct: 261 NGYIKVKSGLAGDATQTNIKGVFAAGDVADHV 292 >5U63-A nrPDB Length = 321 Score = 102 bits (255), Expect = 3e-22, Method: Composition-based stats. Identities = 55/335 (16%), Positives = 114/335 (34%), Gaps = 63/335 (18%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 ++ KH L++G G G +A AA K +LV GG + Sbjct: 5 SDIKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQGG--------------QLTTT 50 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + ++ + L + L + +++R+ +L + Sbjct: 51 DEIENWPGDFEMTTGSGLMQRMLQHAEKFETEIVFDHINRV------DLSSRPFKLF--- 101 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP--------GFELGTDSDGF 190 + ++ + +++ATG A + +P G DGF Sbjct: 102 ---------------GDVQNFTCDALIIATGASARY-IGLPSEENYKGRGVSACATCDGF 145 Query: 191 FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 F + K V V+G G +E A + S HL+ R ++ + ++ + + + + Sbjct: 146 F---YRNKPVGVIGGGNTAVEEALYLANIASTVHLIHRRDSF--RAEKILIDRLYKKVEE 200 Query: 251 EGINVHKLSKIVKVEKN---VETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVG 307 I +H + +V + V +L K +D L IG + + + Sbjct: 201 GKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPNTEIFQGQLE 260 Query: 308 IKLNSHDQIIADEYQ-----NTNVPNIYSLGDVVG 337 + + I+ T+V +++ GDV+ Sbjct: 261 LN---NGYIVVKSGLDGNATATSVEGVFAAGDVMD 292 >5JFC-L nrPDB Length = 474 Score = 102 bits (254), Expect = 4e-22, Method: Composition-based stats. Identities = 56/352 (15%), Positives = 107/352 (30%), Gaps = 63/352 (17%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVSH 84 +IG G G+ A A G + + EA GG V+ Y Sbjct: 157 VAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG-----------VLIYG---IPEFRL 202 Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKD 144 E + L + + + L Y G R Sbjct: 203 PKEIVKKELENLRRLGVKIETNVLV-GKTITFEELREEYDAIFIGTGA----GTPRIYPW 257 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVG 204 V + + E + +++ A P ++ + K+V V+G Sbjct: 258 PGVNLNGIYSANEFLTRINLMKA--------YKFPEYDTPI---------KVGKRVAVIG 300 Query: 205 AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQN--TITDHYVKEGINVHKLSKIV 262 G ++ A LG+E ++ R + + H +EG+ L Sbjct: 301 GGNTAMDAARSALRLGAEVWILYRRTR------KEMTAREEEIKHAEEEGVKFMFLVTPK 354 Query: 263 KVEKNVETDKLKIHMN------------------DSKSIDDVDELIWTIGRKSHLGMGSE 304 + + + I + I + D I IG+ + Sbjct: 355 RFIGDENGNLKAIELEKMKLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQTPNKTFLET 414 Query: 305 NVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRL 356 G+K++ +I+ DE T++P +++ GD + +A+ GRK + + Sbjct: 415 VPGLKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAI 466 Score = 47.2 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 41/126 (32%), Gaps = 25/126 (19%) Query: 182 ELGTDSDGFFR----LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV----- 232 E G D + ++ KKV ++GAG G+ A +G E + Sbjct: 135 EHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLI 194 Query: 233 --LRKF--DECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDE 288 + +F + I ++ + G+ + + K + + ++ D Sbjct: 195 YGIPEFRLPKEIVKKELENLRRLGVKIETNVLVGK------------TITFEELREEYDA 242 Query: 289 LIWTIG 294 + G Sbjct: 243 IFIGTG 248 >1F6M-A nrPDB Length = 320 Score = 102 bits (254), Expect = 4e-22, Method: Composition-based stats. Identities = 64/340 (18%), Positives = 114/340 (33%), Gaps = 72/340 (21%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLAT 80 TKH L++G G G +A AA + +L+ GG Sbjct: 3 TKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGG--------------------- 41 Query: 81 RVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWAR 140 L NWP + L G E Sbjct: 42 --------------QLTTTTEVENWP-------GDPNDLTGPLLMERMHEHATKFETEII 80 Query: 141 FNKDGNVEVQKR----DNTTEVYSANHILVATGGKAIFPENIP--------GFELGTDSD 188 F+ V++Q R + Y+ + +++ATG A + +P G D Sbjct: 81 FDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARY-LGLPSEEAFKGRGVSASATCD 139 Query: 189 GFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHY 248 GFF + +KV V+G G +E A + SE HL+ R + + ++ + + D Sbjct: 140 GFF---YRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGF--RAEKILIKRLMDKV 194 Query: 249 VKEGINVHKLSKIVKVEKN--VETDKLKIHMNDSKSIDDVDE--LIWTIGRKSHLGMGSE 304 I +H + +V + T +S +I+ +D L IG + + Sbjct: 195 ENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEG 254 Query: 305 NVGIKLNSHDQIIADEY-----QNTNVPNIYSLGDVVGKV 339 + + + I T++P +++ GDV+ + Sbjct: 255 QLEL---ENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHI 291 >4YRY-B nrPDB Length = 468 Score = 99 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 69/359 (19%), Positives = 124/359 (34%), Gaps = 66/359 (18%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDL 78 +K V+G G G+ +A A G + EA GG V G +P Sbjct: 137 GSKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGGVLVY-G-IP---------- 184 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + + K + F+ + V L Y G Sbjct: 185 --EFRLPKRIVEREVSYIRKLGVNFHLNTVV-GKTVKVKELLSEYDAVFIGTGA----GT 237 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK 198 +F + + E + +++ A +FPE +G K Sbjct: 238 PKFMGIPGTNLNGVYSANEFLTRVNLMKA----YLFPEYDTPIRVG-------------K 280 Query: 199 KVVVVGAGYIGIELAGVFHGLGSE-THLVIRGETVLRKFDECIQNTITDHYV--KEGINV 255 KV V+GAG ++ A LG+E ++V R + + +++ +EGI Sbjct: 281 KVAVIGAGNTAMDAARSALRLGAEKVYIVYRRT------EREMPARREEYHHALEEGIEF 334 Query: 256 HKLSKIVKVEKNVETDKLK-------------------IHMNDSKSIDDVDELIWTIGRK 296 L+ ++ + + + + S + +VD +I IG+ Sbjct: 335 LWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQG 394 Query: 297 SHLGMGSENVGIKLNSHDQIIADEYQ-NTNVPNIYSLGDVVGKVELTPVAIAAGRKLSN 354 + + SE G++LN I ADE T+V +++ GD+V A+ AG+K + Sbjct: 395 PNRVLLSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIVTGAATVIKAMGAGKKAAQ 453 >2ZBW-A nrPDB Length = 335 Score = 98.4 bits (244), Expect = 6e-21, Method: Composition-based stats. Identities = 59/338 (17%), Positives = 116/338 (34%), Gaps = 56/338 (16%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGG--TCVNVGCVPKKVMWYA 75 H D L++G G G+ + G V+ GG T + P+K ++ Sbjct: 1 MAADHTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALY----PEKYIYDV 56 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV 135 + G + D + V N +Y E ++ Sbjct: 57 A------------GFPKVYAKD----------LVKGLVEQVAPFNPVYSLGERAETLERE 94 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENI--PGFELGTDSDGFFRL 193 + + Y+A +++A G A P I PG ++ + Sbjct: 95 GDLFKVT----------TSQGNAYTAKAVIIAAGVGAFEPRRIGAPGEREFEGRGVYYAV 144 Query: 194 EEQP----KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 + + K+V++VG G ++ A L+ R + E + + Sbjct: 145 KSKAEFQGKRVLIVGGGDSAVDWALNLLDTARRITLIHRRPQF--RAHEASVKELMKAHE 202 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSID--DVDELIWTIGRKSHLGMG-SENV 306 + + V ++ +VE + + N ++ +VD ++ G +G N Sbjct: 203 EGRLEVLTPYELRRVEGDERVRWAVVFHNQTQEELALEVDAVLILAGYI--TKLGPLANW 260 Query: 307 GIKLNSHDQIIADEYQNTNVPNIYSLGDVV---GKVEL 341 G+ L ++I D T++P +Y+ GD+V GK+ L Sbjct: 261 GLAL-EKNKIKVDTTMATSIPGVYACGDIVTYPGKLPL 297 >5VJ7-A nrPDB Length = 476 Score = 98.0 bits (243), Expect = 7e-21, Method: Composition-based stats. Identities = 58/356 (16%), Positives = 109/356 (30%), Gaps = 70/356 (19%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHA 85 +IG G G+ A A G + + E + + T Sbjct: 157 VAIIGAGPAGLTCAADLAKMGYEVTIYE-----------------ALHQPGGVLT----- 194 Query: 86 NEYGLYQNLPLDKEHLTFNWPEF----KQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 YG+ L KE L + + + ++ Q+ L++ + Sbjct: 195 --YGI-PEFRLPKEILRKELKKLSLLGVEIKTDHIVGKTITIQELLQEYDAVFI---GTG 248 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVV 201 + N +YSAN L + + E T ++ Sbjct: 249 AGTPKLPNIPGINLNGIYSANEFL----TRINLMKAYKFPEYDTPIVVGKKVVVIG---- 300 Query: 202 VVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTIT--DHYVKEGINVHKLS 259 AG ++ A LG+E + R E + I H +EG+ Sbjct: 301 ---AGNTAMDAARSALRLGAEVTIAYRRGR------EDMTARIEEVKHAEEEGVKFMFFV 351 Query: 260 KIVKV-------------------EKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 V+ E+ K KI + D +I IG+ + Sbjct: 352 NPVEFIGDENGNVKAVKFEKMKPLEERDSRGKRKIVGTGEYITVEADTVIIAIGQTPNKV 411 Query: 301 MGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRL 356 + +K++ +I+ DE T++P +++ GD + +A+ GRK + + Sbjct: 412 LWRATPELKVDEWGRIVVDENLMTSIPGVFAGGDAIRGEATVILAMGDGRKAAKAI 467 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 38/126 (30%), Gaps = 25/126 (19%) Query: 182 ELGTDSDGFFR----LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV----- 232 E G D + ++ KKV ++GAG G+ A +G E + Sbjct: 135 EHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGGVLT 194 Query: 233 --LRKF--DECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDE 288 + +F + I G+ + + K + + + + D Sbjct: 195 YGIPEFRLPKEILRKELKKLSLLGVEIKTDHIVGK------------TITIQELLQEYDA 242 Query: 289 LIWTIG 294 + G Sbjct: 243 VFIGTG 248 >5USX-A nrPDB Length = 319 Score = 96.9 bits (240), Expect = 2e-20, Method: Composition-based stats. Identities = 66/338 (19%), Positives = 110/338 (32%), Gaps = 69/338 (20%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 ++ KH L++G G G +A AA +L+ GG Sbjct: 2 SDMKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQGG------------------- 42 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 L NWP + L G + KE + Sbjct: 43 ----------------QLTTTTEVENWPGDPEG-------LTGPGLMDRMKEHAERFETE 79 Query: 139 ARFNKDGNVEVQKR----DNTTEVYSANHILVATGGKAIFPE-------NIPGFELGTDS 187 F+ V+ R YS + ++++TG A + G Sbjct: 80 IIFDHINEVDFSTRPFVLKGDAASYSCDALIISTGASAKYLGLESEEAFKGRGVSACATC 139 Query: 188 DGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDH 247 DGFF + +KV VVG G +E A + +E HL+ R ++ + ++ + N + D Sbjct: 140 DGFF---YRNQKVAVVGGGNTAVEEALYLSNIAAEVHLIHRRDSF--RAEKILINRLMDK 194 Query: 248 YVKEGINVHKLSKIVKV---EKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSE 304 I +H + +V E V +LK DV IG + + Sbjct: 195 VQNGNIVLHTDRVLDEVLGDEMGVTGVRLKDVKTGGTEELDVMGAFIAIGHSPNTQIFQG 254 Query: 305 NVGIKLNSHDQIIADEYQ-----NTNVPNIYSLGDVVG 337 + +K I+ T+V I++ GDV+ Sbjct: 255 QLDMK---DGYILVKSGLEGNATQTSVEGIFAAGDVMD 289 >4EMJ-A nrPDB Length = 410 Score = 95.3 bits (236), Expect = 5e-20, Method: Composition-based stats. Identities = 54/272 (19%), Positives = 103/272 (37%), Gaps = 29/272 (10%) Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 A + +L D+ HL ++ P + L+G ++ + D G AR + Sbjct: 22 RAEGFEGRISLIGDEPHLPYDRPSLSKAV------LDGSLERPPILAEADWY-GEARIDM 74 Query: 144 DGNVEVQKRDNTTEVYS--------ANHILVATGGKAI---FP-ENIPGFELGTDSDGFF 191 EV D T S A+ I++ATG +A P +PG Sbjct: 75 LTGPEVTALDVQTRTISLDDGTTLSADAIVIATGSRARTMALPGSQLPGVVTLRTYGDVQ 134 Query: 192 RLEEQ---PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDH 247 L + ++++VG G IG E+A LG ++ G+ +L R I + Sbjct: 135 VLRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAWLRGL 194 Query: 248 YVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVG 307 + G+ V + +V + +++ +D +S D + +G + + + G Sbjct: 195 LTELGVQVELGTGVVGFSGEGQLEQV--MASDGRSFV-ADSALICVGAEPADQL-ARQAG 250 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDVVGKV 339 + + +I D T ++++GDV Sbjct: 251 LACDR--GVIVDHCGATLAKGVFAVGDVASWP 280 Score = 29.1 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 17/115 (14%), Positives = 37/115 (32%), Gaps = 19/115 (16%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD-ECIQNTI------------- 244 V ++G G G A G E + + G+ +D + + Sbjct: 4 HVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAE 63 Query: 245 TDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 D Y + I++ ++ ++ T L D + D ++ G ++ Sbjct: 64 ADWYGEARIDMLTGPEVTALDVQTRTISL-----DDGTTLSADAIVIATGSRART 113 Score = 27.9 bits (61), Expect = 9.7, Method: Composition-based stats. Identities = 14/51 (27%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 5 TKQTFRSLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 T +T+ +Q+ + T L++GGG G A A G ++EA Sbjct: 126 TLRTYGDVQV-LRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAG 175 >3LZX-A nrPDB Length = 332 Score = 91.1 bits (225), Expect = 1e-18, Method: Composition-based stats. Identities = 64/357 (17%), Positives = 123/357 (34%), Gaps = 61/357 (17%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYA 75 M +TK YD +IGGG G+ +A A ++E+ LGG Sbjct: 1 MREDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGG---------------- 44 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV 135 L+ Y + + + L N E K D + L + + Sbjct: 45 -QLSALYPEKYIYDVAGFPKIRAQELINNLKEQMAKFDQTI-CLEQAVESVEK------- 95 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPE--NIPGFELGTDSDGFFRL 193 F K E + + +++ G A P + E + + + Sbjct: 96 QADGVF---------KLVTNEETHYSKTVIITAGNGAFKPRKLELENAEQYEGKNLHYFV 146 Query: 194 EEQPK----KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 ++ K +V ++G G ++ A + + E ++ R + ++ Sbjct: 147 DDLQKFAGRRVAILGGGDSAVDWALMLEPIAKEVSIIHRRDKF------RAHEHSVENLH 200 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKI--HMNDSKSIDDVDELIWTIGRKSHLGMGSENVG 307 +NV ++ + ++L + D K I ++D+LI G S LG +N G Sbjct: 201 ASKVNVLTPFVPAELIGEDKIEQLVLEEVKGDRKEILEIDDLIVNYGFVSSLG-PIKNWG 259 Query: 308 IKLNSHDQIIADEYQNTNVPNIYSLGDVV---GKVEL-------TPVAIAAGRKLSN 354 + + + I+ TN+ ++ GD+ GKV L P A+ + + Sbjct: 260 LDI-EKNSIVVKSTMETNIEGFFAAGDICTYEGKVNLIASGFGEAPTAVNNAKAYMD 315 Score = 36.8 bits (84), Expect = 0.023, Method: Composition-based stats. Identities = 27/201 (13%), Positives = 60/201 (29%), Gaps = 34/201 (16%) Query: 200 VVVVGAGYIGIELAGVFHGL-GSETHLVIRGETVL----------RKFD---------EC 239 + ++G G +G+ + G+ + ++ + +D + Sbjct: 10 ITIIGGGPVGL-FTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKIRAQE 68 Query: 240 IQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIG---RK 296 + N + + K + + VEK + + ++ +I T G K Sbjct: 69 LINNLKEQMAKFDQTICLEQAVESVEKQADGV---FKLVTNEETHYSKTVIITAGNGAFK 125 Query: 297 SHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSL---GD--VVGKVELTPVAIAAGRK 351 + EN + D+ Q + ++ GD V + L P+A Sbjct: 126 PR-KLELENAEQYEGKNLHYFVDDLQKFAGRRV-AILGGGDSAVDWALMLEPIAKEVSII 183 Query: 352 LSNRLFGPEKFRNDKLDYENV 372 F + + L V Sbjct: 184 HRRDKFRAHEHSVENLHASKV 204 >5W4C-A nrPDB Length = 371 Score = 91.1 bits (225), Expect = 1e-18, Method: Composition-based stats. Identities = 60/331 (18%), Positives = 112/331 (33%), Gaps = 61/331 (18%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHA 85 ++IG G GG +A A + +L E M Sbjct: 33 VVIIGSGPGGHTAAIYLARANLEPVLYEG-----------------MLAN---------- 65 Query: 86 NEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK-- 143 G L N+P F + + ++ E+ ++ Sbjct: 66 ---GFAPGGQLTTTTDVENFPGFPEGVTGT--EMMDKFRAQSERFGTKIITETVARVDLS 120 Query: 144 --DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE----LGTDS----DGFFRL 193 + + E +A+ I++ATG A +PG E G + DG + Sbjct: 121 VRPFKYWTEGEEEEHEFMTADTIILATGASAKR-LFLPGEETYWQSGISACAVCDGAVPI 179 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 Q K + V+G G E A GS ++++R + + + + + +T H Sbjct: 180 FRQ-KPLAVIGGGDSAAEEATYLTKYGSHVYVLVRRDEL--RASKIMAKRLTSH-----P 231 Query: 254 NVHKLSKIVKVEKNVETDKLK-IHMNDSKSIDDVDE----LIWTIGRKSHLGMGSENVGI 308 V L V E + + L + + ++K+ + D L + IG + + + Sbjct: 232 KVTVLWNTVATEAKGDGEVLTSLTIKNTKTGETGDLPVNGLFYAIGHEPATSLV--KSQV 289 Query: 309 KLNSHDQII-ADEYQNTNVPNIYSLGDVVGK 338 +L+S I T+V +++ GDV K Sbjct: 290 ELDSDGYIKTVPGTSQTSVHGVFAAGDVQDK 320 >4CBQ-A nrPDB Length = 314 Score = 89.6 bits (221), Expect = 3e-18, Method: Composition-based stats. Identities = 55/330 (16%), Positives = 109/330 (33%), Gaps = 51/330 (15%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 + +D ++IG G +A K ++ E GG Sbjct: 1 MSNIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGV------------------- 41 Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWA 139 L + N+P F D +N + EK ++ Sbjct: 42 -----------AAGGQLTTTTIIENFPGFPNGIDGNELMMN--MRTQSEKYGTTIITETI 88 Query: 140 RFNKDGNVEVQKRDNTTEVYSANHILVATGG---KAIFPENIPGFELGTDS----DGFFR 192 + + +++ATG + P ++ G + DG Sbjct: 89 DHVDFSTQPFKLFTEEGKEVLTKSVIIATGATAKRMHVPGEDKYWQNGVSACAICDGAVP 148 Query: 193 LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 + K ++VVG G +E A GS+ ++ R + + + +Q + +H Sbjct: 149 IFRN-KVLMVVGGGDAAMEEALHLTKYGSKVIILHRRDAF--RASKTMQERVLNHPK--- 202 Query: 253 INVHKLSKIVKVEKNVE---TDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIK 309 I V S++V++E + + K+ ++ + V L + IG + +K Sbjct: 203 IEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSKFL--GGQVK 260 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVVGKV 339 I+ E T+V +++ GDV +V Sbjct: 261 TADDGYILT-EGPKTSVDGVFACGDVCDRV 289 >5YGQ-A nrPDB Length = 342 Score = 88.4 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 61/355 (17%), Positives = 121/355 (34%), Gaps = 63/355 (17%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASD 77 T T D L++G G G+ + K LV+ +GG C ++ Sbjct: 2 TETIKTDVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQC--------------AE 47 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 L E +Y + ++ + N + + E V+ + Sbjct: 48 LY------PEKPIYDIPGIPMVTGHGLTEALMEQ----IKPFNPTFHLSEMVENVEKI-- 95 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPEN--IPGFELGTDSDGFFRLEE 195 D V V+ ++VA GG + P+ +PG E + + + + Sbjct: 96 -----GDPGFRVTTNAGK--VFECTVLVVAAGGGSFLPKRPPVPGVEAYEGTSVHYAVRK 148 Query: 196 Q----PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 K +++VG G ++ + + LV R + R ++ V Sbjct: 149 MEDFRGKDILIVGGGDSALDWTLNLNPIAKSMTLVHRRDDF-RGAPHSVEQM--RQLVAS 205 Query: 252 G-INVHKLSKIVKVEKNVETDKLKIHMNDSKSI-DDVDELI------WTIGRKSHLGMGS 303 G +++ N + + +ND+ + D ++ +G ++ G+ Sbjct: 206 GKLDLKIGQITELQGDNGQLTGATVKLNDNTTSQIKCDAMLPFFGLTMKLGPVANWGLDL 265 Query: 304 ENVGIKLNSHDQIIADE-YQNTNVPNIYSLGDVV---GKVELTPVAIAAGRKLSN 354 EN + I D TNVP I+++GD+ GK++L G ++ Sbjct: 266 EN--------NLIPVDTGTFETNVPGIFAIGDINTYPGKLKLILSGFHEGALMAQ 312 >5KVH-A nrPDB Length = 543 Score = 86.5 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 52/260 (20%), Positives = 103/260 (39%), Gaps = 42/260 (16%) Query: 137 GWARFNKDGNVEVQKRDNTTEV-----YSANHILVATGGKAIFPENI--PGFELGTDSD- 188 G A V++ RDN ++ + L+ATGG I G E+ + + Sbjct: 148 GVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTL 207 Query: 189 -----GFFRLEEQP---KKVVVVGAGYIGIELAGVF----HGLGSETHLVI----RGETV 232 F LE+ K + ++G G++G ELA LG+E + + Sbjct: 208 FRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEVIQLFPEKGNMGKI 267 Query: 233 LRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWT 292 L ++ + N + +EG+ V + + V V + KL I + D + + + D ++ Sbjct: 268 LPEY---LSNWTMEKVRREGVKVMPNAIVQSV--GVSSGKLLIKLKDGRKV-ETDHIVAA 321 Query: 293 IGRKSHLGMGSENVGIKLNSH-DQIIADEYQNTNVPNIYSLGDVV-------GKVELTP- 343 +G + ++ + ++ G++++S + NI+ GD G+ + Sbjct: 322 VGLEPNVEL-AKTGGLEIDSDFGGFRVNAELQAR-SNIWVAGDAACFYDIKLGRRRVEHH 379 Query: 344 -VAIAAGRKLSNRLFGPEKF 362 A+ +GR + G K Sbjct: 380 DHAVVSGRLAGENMTGAAKP 399 >3ISH-A nrPDB Length = 311 Score = 85.7 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 56/328 (17%), Positives = 100/328 (30%), Gaps = 65/328 (19%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLV-EAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 D +IGGG G+++ A G K ++ E GG S Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQ------------ITGSSEIENYP 50 Query: 84 HANE--YGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 E GL P ++ F + Sbjct: 51 GVKEVVSGLDFMQPWQEQCFRFGLKHEMTAVQRVSKK----------------------- 87 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG--------FELGTDSDGFFRL 193 D + + D T + A +++ATGG I G DGFF Sbjct: 88 --DSHFVILAEDGKT--FEAKSVIIATGGSPKR-TGIKGESEYWGKGVSTCATCDGFF-- 140 Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 + K+V V+G G +E A + + +L+ R + C T+ + I Sbjct: 141 -YKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRRDGF-----RCAPITLEHAKNNDKI 194 Query: 254 NVHKLSKIVKVEKNVETDK---LKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKL 310 + +++ + +K + K V +G + + + L Sbjct: 195 EFLTPYVVEEIKGDASGVSSLSIKNTATNEKRELVVPGFFIFVGYDVNNAVLKQEDNSML 254 Query: 311 ---NSHDQIIADEYQNTNVPNIYSLGDV 335 + + I+ D TNV +++ GD+ Sbjct: 255 CKCDEYGSIVVDFSMKTNVQGLFAAGDI 282 >4YKF-A nrPDB Length = 521 Score = 83.8 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 50/242 (20%), Positives = 90/242 (37%), Gaps = 34/242 (14%) Query: 117 HRLNGIYQKNLEKEKVDVVFGW-ARFNKDGNVEV---QKRDNTTEVYSANHILVATGGKA 172 +L G + ++++ VDV+ A VE Q + V A I+VATG K Sbjct: 267 QKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKW 326 Query: 173 IFPENIPG--------FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETH 224 N+PG DG + K+V V+G G G+E A G+ Sbjct: 327 R-NMNVPGEDQYRTKGVTYCPHCDGPLF---KGKRVAVIGGGNSGVEAAIDLAGIVEHVT 382 Query: 225 LVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSID 284 L+ K D+ +Q+ + + +++ ++ +V+ + K+ + + Sbjct: 383 LLEFAPE--MKADQVLQDKLRSL---KNVDIILNAQTTEVKGDGS----KVVGLEYRDRV 433 Query: 285 DVDE-------LIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVG 337 D + IG + E ++ N +II D TNV +++ GD Sbjct: 434 SGDIHNIELAGIFVQIGLLPNTNW-LEGA-VERNRMGEIIIDAKCETNVKGVFAAGDCTT 491 Query: 338 KV 339 Sbjct: 492 VP 493 >6GAS-A nrPDB Length = 331 Score = 83.8 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 70/358 (19%), Positives = 130/358 (36%), Gaps = 69/358 (19%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYA 75 ++ N K YD +IGGG G+ +A A ++E+ LGG Sbjct: 3 VAENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGG---------------- 46 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVV 135 L+ Y + + + L N E +K D V +E VD + Sbjct: 47 -QLSALYPEKYIYDVAGFPKVRAQELVDNLKEQMKKFDPTVCL----------EEAVDTL 95 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENI----------PGFELGT 185 A DG ++ + + + +++ G A P + Sbjct: 96 EKQA----DGIFKLVTNK---QTHYSKSVIITAGNGAFQPRRLELEGTAKYEKKNLHYFV 148 Query: 186 DSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTIT 245 D F K+VVV G G ++ + + + +V R + ++++ Sbjct: 149 DDMNKFA----GKRVVVFGGGDSAVDWTMMLEPIAEKVTIVHRRDKF-----RAHEHSVE 199 Query: 246 DHYVKEGINVHKLSKIVKVEKNVETDKLKI--HMNDSKSIDDVDELIWTIGRKSHLGMGS 303 + V V++ + + +++ + + K I DVD++I G S LG Sbjct: 200 NLMNSRA-EVSTPYVPVELIGDDKIEQVVLQHVKTEEKVIIDVDDVIVNYGFVSSLG-PI 257 Query: 304 ENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVV---GKVEL-------TPVAIAAGRK 351 +N G+ + + I+ + TN+P IY+ GD+ GKV+L P A+ + Sbjct: 258 KNWGLDI-QKNSILVNSKMETNIPGIYAAGDICTYEGKVKLIACGFGEAPTAVNNAKA 314 >5XHU-A nrPDB Length = 329 Score = 83.0 bits (204), Expect = 3e-16, Method: Composition-based stats. Identities = 59/319 (18%), Positives = 114/319 (35%), Gaps = 43/319 (13%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGGTCVNVGCVPKKVMWYASDLATRV 82 YD +IGGG G+ +A KT ++E LGG P+K++ + Sbjct: 3 YDVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLF--FPEKIIRDIGGIPGIA 60 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 G L ++ TF+ +R RL+ E Sbjct: 61 ------GKQLIEQLKEQAATFDPDIVLNQRVTGFERLDDGTIVLTGSEGKKHYTRTVILA 114 Query: 143 -KDGNVEVQKRDNT-TEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKV 200 G +EV + D+ Y+ ++ G + F + K+V Sbjct: 115 CGMGTLEVNEFDSEDAARYAGKNL-----------------HYGVEKLDAF----KGKRV 153 Query: 201 VVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSK 260 V+ G G ++ A + + +V R E + + + + V + Sbjct: 154 VISGGGDTAVDWANELEPIAASVTVVHRREEFG-GMESSVTK-----MKQSSVRVLTPYR 207 Query: 261 IVKV---EKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII 317 + ++ E+ +++ + + + ++DELI G K LG E G+++ ++ Sbjct: 208 LEQLNGDEEGIKSVTVCHTESGQRKDIEIDELIINHGFKIDLGPMME-WGLEI-EEGRVK 265 Query: 318 ADEYQNTNVPNIYSLGDVV 336 AD + TN+P ++ GD Sbjct: 266 ADRHMRTNLPGVFVAGDAA 284 >3R9U-A nrPDB Length = 315 Score = 82.6 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 57/328 (17%), Positives = 106/328 (32%), Gaps = 67/328 (20%) Query: 25 DYLVIGGGSGGVASARRAASYGAK-TLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVS 83 D +IGGG G+++ A G K ++ E GG + +V Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQ------ITSSSEIENYPGVAQVM 59 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 G+ P ++ + F + + Sbjct: 60 D----GISFMAPWSEQCMRFGLKHEMVGVEQILKN------------------------S 91 Query: 144 DGNVEVQKRDNTTEVYSANHILVATGGKAIFPENI-------PGFELGTDSDGFFRLEEQ 196 DG+ ++ TE+ A ++V TG G DGFF + Sbjct: 92 DGSFTIKLEGGKTEL--AKAVIVCTGSAPKKAGFKGEDEFFGKGVSTCATCDGFF---YK 146 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 K+V V+G G +E A + S+ +L+ R + +T+ E I + Sbjct: 147 NKEVAVLGGGDTALEEALYLANICSKIYLIHRRDEF-----RAAPSTVEKVKKNEKIELI 201 Query: 257 KLSKIVKVEKNVETD-KLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLN---- 311 + + +V + +K+ + D D I+T +G+ N +K + Sbjct: 202 TSASVDEVYGDKMGVAGVKVKLKDGSIRDLNVPGIFT-----FVGLNVRNEILKQDDSKF 256 Query: 312 -----SHDQIIADEYQNTNVPNIYSLGD 334 Q+ D T+V +++ GD Sbjct: 257 LCNMEEGGQVSVDLKMQTSVAGLFAAGD 284 >6BPY-A nrPDB Length = 374 Score = 82.2 bits (202), Expect = 4e-16, Method: Composition-based stats. Identities = 57/335 (17%), Positives = 107/335 (31%), Gaps = 52/335 (15%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLA 79 H ++IG G +A + K +L E GT A Sbjct: 1 GMVHTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGT-------------AAGGQL 47 Query: 80 TRVSHANEY-GLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 T + + G + E + + + E + V Sbjct: 48 TTTTDIENFPGFPDGIG---------GAELMENMRK--QSIRFGTEVI--TETISRVDLS 94 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE----LGTDS----DGF 190 ++ K E + +A+ +++ATG A N+PG E G + DG Sbjct: 95 SKPFKLWT-EWNDGPDKEPACTADAVIIATGANARR-LNLPGEETYWQNGISACAVCDGA 152 Query: 191 FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 + K + V+G G E A GS +++R + + + + + + H Sbjct: 153 VPIFRN-KPLYVIGGGDSAAEEAMFLAKYGSSVTVLVRRDKL--RASKAMAKRLLAHPK- 208 Query: 251 EGINVHKLSKIVKVEKNVETDKLKIHM------NDSKSIDDVDELIWTIGRKSHLGMGSE 304 + V + +V + + L H+ + I D + L + +G + Sbjct: 209 --VTVRFNTVATEVLGEKKPNGLMTHLRIKNTVTGEEEIVDANGLFYAVGHDPATALV-- 264 Query: 305 NVGIKLNSHDQIIADE-YQNTNVPNIYSLGDVVGK 338 I L+ II T+ +++ GDV K Sbjct: 265 KGQIDLDEDGYIITKPGTSYTSREGVFACGDVQDK 299 >3D8X-A nrPDB Length = 326 Score = 80.7 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 52/325 (16%), Positives = 102/325 (31%), Gaps = 56/325 (17%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHA 85 +IG G +A A K +L E +M +++ Sbjct: 13 VTIIGSGPAAHTAAIYLARAEIKPILYEG----------------MMANGIAAGGQLTTT 56 Query: 86 NEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDG 145 E + P + R+ E + + Sbjct: 57 TEIENFPGFPDGLTGSEL----MDRMREQSTK---------FGTEIITETVSKVDLSSKP 103 Query: 146 NVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE----LGTDS----DGFFR-LEEQ 196 + + E + + I++ATG A ++PG E G + DG + Sbjct: 104 FKLWTEFNEDAEPVTTDAIILATGASAKR-MHLPGEETYWQKGISACAVCDGAVPIFRNK 162 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 P + V+G G E A GS+ +++R + + +TI ++ + Sbjct: 163 P--LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL-------RASTIMQKRAEKNEKIE 213 Query: 257 KLSKIVKVEKNVETDKL-KIHMNDSKSIDDVDE----LIWTIGRKSHLGMGSENVGIKLN 311 L V +E + L + + ++K ++ D L + IG + + + + Sbjct: 214 ILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQ--VDTD 271 Query: 312 SHDQII-ADEYQNTNVPNIYSLGDV 335 I T+VP ++ GDV Sbjct: 272 EAGYIKTVPGSSLTSVPGFFAAGDV 296 >1FL2-A nrPDB Length = 310 Score = 79.9 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 50/242 (20%), Positives = 90/242 (37%), Gaps = 34/242 (14%) Query: 117 HRLNGIYQKNLEKEKVDVVFGW-ARFNKDGNVEV---QKRDNTTEVYSANHILVATGGKA 172 +L G + ++++ VDV+ A VE Q + V A I+VATG K Sbjct: 56 QKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKW 115 Query: 173 IFPENIPG--------FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETH 224 N+PG DG + K+V V+G G G+E A G+ Sbjct: 116 R-NMNVPGEDQYRTKGVTYCPHCDGPLF---KGKRVAVIGGGNSGVEAAIDLAGIVEHVT 171 Query: 225 LVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSID 284 L+ K D+ +Q+ + + +++ ++ +V+ + K+ + + Sbjct: 172 LLEFAPE--MKADQVLQDKLRSL---KNVDIILNAQTTEVKGDGS----KVVGLEYRDRV 222 Query: 285 DVDE-------LIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVG 337 D + IG + E ++ N +II D TNV +++ GD Sbjct: 223 SGDIHNIELAGIFVQIGLLPNTNW-LEGA-VERNRMGEIIIDAKCETNVKGVFAAGDCTT 280 Query: 338 KV 339 Sbjct: 281 VP 282 >6GAR-A nrPDB Length = 349 Score = 79.5 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 67/368 (18%), Positives = 135/368 (36%), Gaps = 60/368 (16%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGGTCVNVGCVPKKVMWYASDLATRV 82 +D VIGGG G+ SA + +T ++E LGG ++V P+K++W L Sbjct: 7 FDVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPHLGGK-IHV--YPEKMIWDVGGL---- 59 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFN 142 L + + L + L+ KV+ Sbjct: 60 ------------------LPVTGDKLIE--QLVQQGLTFKPEVVLDT-KVE------SII 92 Query: 143 KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPEN--IPGFELGTDSDGFFRLEEQ---- 196 ++ + + +T E + + ++VATG + P+ I G E S+ + ++ Sbjct: 93 RNQDGTFTLKTSTGEEHFSKTVIVATGSGILKPQKLSIEGAERFEVSNLNYTVKSLKRFK 152 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 K V++ G G ++ A + + ++ R E L + + + Sbjct: 153 GKTVIISGGGNSAVDWANELEPIAKKVYVTYRKEE-LSGHEAQV-----KQLMNSSAECF 206 Query: 257 KLSKIVKVEKNVETDKLKI-----HMNDSKSIDDVDELIWTIGRKSHLGMGSEN--VGIK 309 + I K+ + ++ H S +DE+I G + + + EN + + Sbjct: 207 FNTSITKLIAGDNHEAIEYVELTNHETGEVSHLPIDEVIINHGYERDITL-LENSELDVA 265 Query: 310 LNSHDQIIADEYQNTNVPNIYSLGDVV---GKVELTPVAIAAGRKLSNRLFGPEKFRNDK 366 + + I + ++V +Y+ GD++ GK+ L A N+ + + D Sbjct: 266 IIDNYYIAGNANSESSVDGLYAAGDILKHEGKLHLIAGAFQDAGNAVNK--AKQFIQPDA 323 Query: 367 LDYENVPS 374 +Y V S Sbjct: 324 SEYGMVSS 331 >5MIU-A nrPDB Length = 535 Score = 79.2 bits (194), Expect = 4e-15, Method: Composition-based stats. Identities = 52/267 (19%), Positives = 100/267 (37%), Gaps = 40/267 (14%) Query: 126 NLEKEKVDVVFGW-ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENI--PGFE 182 N+E V V+ G V+ D + + L+ATGG I G E Sbjct: 141 NIENGGVAVLTGKKVVHLDVRGNMVKLNDGSQ--ITFEKCLIATGGTPRSLSAIDRAGAE 198 Query: 183 LGTDSD------GFFRLEEQP---KKVVVVGAGYIGIELAGVFHGL----GSETHLVI-- 227 + + + F LE+ K + V+G G++G ELA G E + Sbjct: 199 VKSRTTLFRKIGDFRALEKISREVKSITVIGEGFLGSELACALGRKSQASGIEVIQLFPE 258 Query: 228 --RGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDD 285 +L + + N + +EG+ V + + V V +L I + D + + + Sbjct: 259 KGNMGKILP---QYLSNWTMEKVKREGVKVMPNAIVQSV--GVSGGRLLIKLKDGRKV-E 312 Query: 286 VDELIWTIGRKSHLGMGSENVGIKLNSH-DQIIADEYQNTNVPNIYSLGDVV-------G 337 D ++ +G + ++ + ++ G++++S + NI+ GD G Sbjct: 313 TDHIVTAVGLEPNVEL-AKTGGLEIDSDFGGFRVNAELQAR-SNIWVAGDAACFYDIKLG 370 Query: 338 KVELTP--VAIAAGRKLSNRLFGPEKF 362 + + A+ +GR + G K Sbjct: 371 RRRVEHHDHAVVSGRLAGENMTGAAKP 397 >2VDC-G nrPDB Length = 456 Score = 78.8 bits (193), Expect = 5e-15, Method: Composition-based stats. Identities = 38/239 (15%), Positives = 74/239 (30%), Gaps = 46/239 (19%) Query: 164 ILVATGGKAIFPENIPG---------FELGTDSD--------GFFR---LEEQPKKVVVV 203 +LVATG PG + T S+ + L K VVV+ Sbjct: 211 VLVATGVYKARDIKAPGSGLGNIVAALDYLTTSNKVSLGDTVEAYENGSLNAAGKHVVVL 270 Query: 204 GAGYIGIELAGVFHGLGSE-THLVIRGETV-LRKFDECIQNTITDHYVKEGINVHKLSKI 261 G G ++ G+ + R + + + H +EG+ + Sbjct: 271 GGGDTAMDCVRTAIRQGATSVKCLYRRDRKNMPGSQREVA-----HAEEEGVEFIWQAAP 325 Query: 262 VKVEKNVETDKLKIH-----------------MNDSKSIDDVDELIWTIGRKSHLGMGS- 303 + ++ + S+ D +I +G + + Sbjct: 326 EGFTGDTVVTGVRAVRIHLGVADATGRQTPQVIEGSEFTVQADLVIKALGFEPEDLPNAF 385 Query: 304 ENVGIKLNSHDQIIADEYQN-TNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEK 361 + +K+ ++ D TN+ +++ GD+V L AI GR + + K Sbjct: 386 DEPELKVTRWGTLLVDHRTKMTNMDGVFAAGDIVRGASLVVWAIRDGRDAAEGIHAYAK 444 >3KLJ-A nrPDB Length = 385 Score = 78.4 bits (192), Expect = 6e-15, Method: Composition-based stats. Identities = 67/382 (17%), Positives = 128/382 (33%), Gaps = 82/382 (21%) Query: 22 KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATR 81 K L++G G G ++A+ A+ G C ++ M + Sbjct: 8 KSTKILILGAGPAGFSAAK--AALGK-------------CDDI------TMINSEKYLPY 46 Query: 82 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG-WAR 140 + +N +D D + + + EK + V+ +A Sbjct: 47 YRPRLNEIIAKNKSID---------------DILIKKNDW-----YEKNNIKVITSEFAT 86 Query: 141 FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDS---DGFFRLEEQP 197 N V + E +++A+G A +P + D +++++ Sbjct: 87 SIDPNNKLVTLKSG--EKIKYEKLIIASGSIAN-KIKVPHADEIFSLYSYDDALKIKDEC 143 Query: 198 K---KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDHYVKEGI 253 K K ++G G +GIELA G+ + I E L R+ D + D + GI Sbjct: 144 KNKGKAFIIGGGILGIELAQAIIDSGTPASIGIILEYPLERQLDRDGGLFLKDKLDRLGI 203 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 ++ S + + +I +G K +L + ++ S Sbjct: 204 KIYTNSN----------------FEEMGDLIRSSCVITAVGVKPNLDFIKDT---EIASK 244 Query: 314 DQIIADEYQNTNVPNIYSLGDVVG----KVELTPVAIAAGRKLSNRLFGPEKFRNDKLDY 369 I+ +++ T++ +IY+ GDV L +A G G + ++ Sbjct: 245 RGILVNDHMETSIKDIYACGDVAEFYGKNPGLINIANKQGEVAGLNACGEDASYSE---- 300 Query: 370 ENVPSVIF--SHPEAGSIGISE 389 +PS I S S G E Sbjct: 301 -IIPSPILKVSGISIISCGDIE 321 >4JNQ-A nrPDB Length = 345 Score = 74.2 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 60/338 (17%), Positives = 115/338 (34%), Gaps = 66/338 (19%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S +H +VIG G G +A AA K +++ GG ++M Sbjct: 21 SMTQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGG----------QLMIT--- 67 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 T V + Y P E + + VH + + + Sbjct: 68 --TDVENYPGYAEPVQGPWMMEQMARQAENVGAQ---IVHDIITEVETTVRP-------- 114 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP--------GFELGTDSDG 189 + + ++ +Y+ + +++ATG +A + + G DG Sbjct: 115 -----------FRLKGDSGTIYTCDALIIATGAQAKW-LGLESEQTFMGGGVSACATCDG 162 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 FF + K VVVVG G +E A + +V R + + ++ +Q+ + Sbjct: 163 FF---YRGKDVVVVGGGNTAVEEALYLSHIAKSVTIVHRRDGF--RAEKIMQDRL---LS 214 Query: 250 KEGINVHKLSKIVKV---------EKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 +E ++V S I ++ V +LK + + IG + Sbjct: 215 RENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQERATHGVFIAIGHAPAVS 274 Query: 301 MGSENVGIKLNSHDQIIAD-EYQNTNVPNIYSLGDVVG 337 + +K + + + T+VP I++ GDV Sbjct: 275 LFEGK--LKQKPNGYLWTAPDSTATDVPGIFAAGDVTD 310 >1VDC-A nrPDB Length = 333 Score = 73.8 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 13/147 (8%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K + V+G G +E A GS+ +++ R + + + +Q I+V Sbjct: 160 KPLAVIGGGDSAMEEANFLTKYGSKVYIIHRRDAF--RASKIMQ---QRALSNPKIDVIW 214 Query: 258 LSKIVKVEKNVETD-----KLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNS 312 S +V+ + E D K+K + S V L + IG + + G++L+S Sbjct: 215 NSSVVEAYGDGERDVLGGLKVKNVVTGDVSDLKVSGLFFAIGHEPATKFL--DGGVELDS 272 Query: 313 HDQIIADE-YQNTNVPNIYSLGDVVGK 338 ++ T+VP +++ GDV K Sbjct: 273 DGYVVTKPGTTQTSVPGVFAAGDVQDK 299 Score = 28.3 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 14/30 (46%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAK 55 VIGGG + A YG+K ++ + Sbjct: 162 LAVIGGGDSAMEEANFLTKYGSKVYIIHRR 191 >5TWC-A nrPDB Length = 344 Score = 69.9 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 62/346 (17%), Positives = 121/346 (34%), Gaps = 56/346 (16%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYASDLA---- 79 D +IGGG G+ ++ A L++ + LGG + P+K++W +A Sbjct: 3 DVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGG---KMRIYPEKIIWDIGGIAPKPC 59 Query: 80 -TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + + GLY + N ++ A H + K ++ Sbjct: 60 HEILKDTIKQGLYFKP-----EVHLNERVVDIRKKAERHFEVETEAGEIYTSKAVIIAIG 114 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPK 198 A ++V+ E Y ++ S F+ K Sbjct: 115 AGIINPKQLDVKG----VERYQLTNL-----------------HYVVQSYRRFKD----K 149 Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 V++ G G ++ A + +V R E V E ++ +TD + + Sbjct: 150 DVLISGGGNTALDWAHDIAKIAKSVTVVYRKEDV--SGHEAMKTLVTD----LNVKLCPK 203 Query: 259 SKIVKVEKNVETDKL-----KIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 ++I + N + + + + + D++I + G + SE KL+ H Sbjct: 204 TRIKYLVGNDDETHISEVVLEHVESGDRHTVKFDDVIISHGFDRCNTLLSETSS-KLDMH 262 Query: 314 DQIIADEYQN--TNVPNIYSLGDVVGKVELTPV---AIAAGRKLSN 354 D + N T++P IY+ GD+V + + A + G +N Sbjct: 263 DDCRVKGFGNTTTSIPGIYACGDIVYHDAKSHLIASAFSDGANAAN 308 >5M5J-A nrPDB Length = 325 Score = 66.8 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 44/340 (12%), Positives = 102/340 (30%), Gaps = 71/340 (20%) Query: 33 SGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQ 92 G+ + A+ K TCV VG + H ++ Sbjct: 27 PAGLTAGIYASRANLK-----------TCVFVG----------------IEHTSQMFTTT 59 Query: 93 NLPLDKEHLTFNWPEFKQKRDAYVHR------LNGIYQKNLEKEKVDVVFGWARFNKDGN 146 ++ H P + ++ ++ +V G+ Sbjct: 60 DVENFPSHTAIKGPALMEAIQNQAEHCGAELLYEDVHSIDVSSRPFKIVHGY-------- 111 Query: 147 VEVQKRDNTTEVYSANHILVATGGKAIFPE-------NIPGFELGTDSDGFFRLEEQPKK 199 E A+ +++ATG A + G D ++ Sbjct: 112 --------ENETTLADALIIATGATARRLDCKGEKEYWQKGVSACAVCDSAMATGKEVVV 163 Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V G + E A + ++ ++V+R + + ++ I + S Sbjct: 164 VG---GGDVACEEATYLTKIATKVYMVLRRDKF-----RASAAMVKKVMNEKLIEIIYDS 215 Query: 260 KIVKVEKNVE---TDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQI 316 I +++ + + + +K + + L W +G + ++ + I Sbjct: 216 AIDEIKGDGKCVTSVSIKNLKDGKTRTLNAGALYWAVGHDPQTSF-LKKGQLEQDEAGYI 274 Query: 317 IADEY--QNTNVPNIYSLGDVVGKV-ELTPVAIAAGRKLS 353 + ++ Q T+V +++ GD + VA +G K + Sbjct: 275 LLKDHPTQRTSVDGVFAAGDCCDHLYRQAVVAAGSGSKAA 314 >4G74-A nrPDB Length = 502 Score = 66.1 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 50/292 (17%), Positives = 91/292 (31%), Gaps = 67/292 (22%) Query: 128 EKEKVDVVFGWARFN--KDGNVEVQKRDNTTEVY----------------SANHILVATG 169 +K V A V ++ +++Y ++++ A G Sbjct: 107 KKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVG 166 Query: 170 GKAIFPENIPGF------------ELGTDSDGFFRLEE---QPK------KVVVV----- 203 + IPG L LE+ PK +++ + Sbjct: 167 AEPNT-FGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGG 225 Query: 204 ------GAG----YIGIELAGVFHGLGSET--HLVIRGETVLRKFDECIQNTITDHYVKE 251 AG Y+ +L L E HLV VL F++ + + H Sbjct: 226 GPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENT 285 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDD---VDELIWTIGR--KSHLGMGSENV 306 I VH + + KVE+ K D K ++ LIW G + + + + Sbjct: 286 SIKVHLRTAVAKVEEKQLLAK--TKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKI 343 Query: 307 GIKLNSHDQIIADEYQNTN-VPNIYSLGDV--VGKVELTPVAIAAGRKLSNR 355 + +S + +++ NI+++GD G VA L+ Sbjct: 344 PEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKN 395 >5JWC-A nrPDB Length = 521 Score = 64.9 bits (157), Expect = 7e-11, Method: Composition-based stats. Identities = 47/246 (19%), Positives = 89/246 (36%), Gaps = 45/246 (18%) Query: 141 FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE----LGTDSDGFFRLEE- 195 F +D + +N +++++A G K NI G + D D ++ + Sbjct: 109 FYEDKYINCIDIENNKVKLFYDYLIIAVGAKTNT-FNINGVDKYAYFVKDIDDALKIRKK 167 Query: 196 ---------QPK----------KVVVVGAGYIGIEL-AGVFHGLGSETHL---------- 225 P V VVG G G+E+ A + E + Sbjct: 168 FLDILEKCTLPNISNEEKKKMLHVAVVGGGPTGVEVTAEFADFINKEVKINYKDIFNFIS 227 Query: 226 ---VIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS 282 + G +L F + I + +++ INV ++ V+K+ + ++ N+ K Sbjct: 228 ISIIEGGNNLLPTFTQNISDFTKENFHNLNINVLTNYYVIDVDKHSFHIQSSLNKNEKKK 287 Query: 283 IDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQI-IADEYQNT-NVP--NIYSLGDVVG- 337 + LIW G + I + +++ I DE +P NIY++GD Sbjct: 288 L-SYGLLIWASGLAQTTLIQKFLKTIPVQANNAILKVDEKLRVIGIPSNNIYAIGDCKKI 346 Query: 338 KVELTP 343 + +L Sbjct: 347 QPKLLH 352 >4NTC-A nrPDB Length = 335 Score = 62.2 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 55/362 (15%), Positives = 120/362 (33%), Gaps = 66/362 (18%) Query: 15 RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWY 74 + +S D L+IG G G+++A A ++ ++ Y Sbjct: 6 KLLSNGALLVDVLIIGAGPAGLSTATGLARQLHTAVVFDSG-----------------VY 48 Query: 75 ASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQK-NLEKEKVD 133 + + + G P + R A L Y + ++ Sbjct: 49 RNAKTQHMHNV--LGWDHRNP-------------AELRAAGRADLTTRYSTIQFQNSTIE 93 Query: 134 VVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFF-- 191 + + N + RDN + +++ATG + P +I G+ ++G + Sbjct: 94 AIR-----QVETNQLFEARDNEGHSWYGRKVVLATGVR-DIPLDIEGYSECW-ANGIYHC 146 Query: 192 -----RLEEQPKKVVVVGAGYIG-----IELAGVFHGLGSETHLVIRGETVLRKFDECIQ 241 E + V V+ G I + LA + L + G L + IQ Sbjct: 147 LFCDGYEERGQETVGVLALGPIANPARALHLARMALRLSESVTIYTNGNEQLA---KEIQ 203 Query: 242 NTITDH-YVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 + G+ + I + EK + +H+ +S+S + + Sbjct: 204 QAAEESPVGASGLKF-EARPIRRFEKGDVAKTVIVHLGESESKTEGFLV-----YNPQTE 257 Query: 301 MG---SENVGIKLNSHDQIIADE-YQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRL 356 + ++ + + + I+ + T+VP ++++GD ++ A++ G + L Sbjct: 258 VNGPFAKQLALNMTEGGDILTTPPFYETSVPGVFAVGDCATPLKAVTPAVSMGSLAAGGL 317 Query: 357 FG 358 Sbjct: 318 VA 319 >5NA1-A nrPDB Length = 408 Score = 62.2 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 48/297 (16%), Positives = 90/297 (30%), Gaps = 57/297 (19%) Query: 123 YQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPG 180 + L+K+KV+ V +V+ +Y + ++VA G + E + Sbjct: 73 VESVLKKDKVNFVQAEVTKIDRDAKKVETNQG---IYDFDILVVALGFVSETFGIEGMKD 129 Query: 181 ----FELGTDSDGF-------FRLEEQPK-------KVVVVGAGYIGIELAGVF------ 216 E + F K ++V GAG+ G+E G Sbjct: 130 HAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFLGELTDRIPE 189 Query: 217 --HGLGSE-----THLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVE 269 G + V +L F E + N + G+ + IV + Sbjct: 190 LCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEFKIATPIVACNEKG- 248 Query: 270 TDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTN-VPN 328 + ++ K + +W G + M G+K +I+ + N N Sbjct: 249 ---FVVEVDGEKQQLNAGTSVWAAGVRGSKLMEESFEGVK---RGRIVTKQDLTINGYDN 302 Query: 329 IYSLGDVV---------GKVELTPVAIAAGRKLS----NRLFGPEKFRNDKLDYENV 372 I+ +GD +A+ G ++ L G + +D V Sbjct: 303 IFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIKRILNGESTEEFEYVDRGTV 359 Score = 32.6 bits (73), Expect = 0.42, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 45/119 (37%), Gaps = 26/119 (21%) Query: 198 KKVVVVGAGYIGIE----LAGVFHGLGSETHLV-------------IRGETVLRKFDECI 240 KKV+V+GAGY G++ L +E L+ L D + Sbjct: 12 KKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNYED--V 69 Query: 241 QNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 + K+ +N +++ K++++ + ++ I D D L+ +G S Sbjct: 70 LYPVESVLKKDKVNFV-QAEVTKIDRDAKKV------ETNQGIYDFDILVVALGFVSET 121 >2CVJ-A nrPDB Length = 180 Score = 60.3 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 46/161 (28%), Gaps = 18/161 (11%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVI----------RGETVLRKFDECIQNTITDHYV 249 V+VVG G G+ A G + ++ R DE + Sbjct: 4 VIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGLLDEPSGEELLRRLE 63 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIK 309 + V K V + + ++ + L+ + L Sbjct: 64 AHARRYGAEVRP-GVVKGVRDMGGVFEVETEEGVEKAERLLLCTHKDPTLPSLLG----- 117 Query: 310 LNSHD-QIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAG 349 L I DE T+ P +Y+ G V I+AG Sbjct: 118 LTRRGAYIDTDEGGRTSYPRVYAAG-VARGKVPGHAIISAG 157 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 20/33 (60%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA 56 +D +V+GGG G+++A A G K L+++ Sbjct: 2 WDVIVVGGGPSGLSAALFLARAGLKVLVLDGGR 34 >2WHD-A nrPDB Length = 351 Score = 59.5 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 37/197 (18%), Positives = 71/197 (36%), Gaps = 27/197 (13%) Query: 158 VYSANHILVATG----------GKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGY 207 A+ ++VATG + I + + FR K + V+G G Sbjct: 132 TVLADTVVVATGAVARRLYFSGSDTYWNRGISACAVCDGAAPIFRN----KPIAVIGGGD 187 Query: 208 IGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVK---- 263 +E GS+ +++ R T + + +Q I V S++V+ Sbjct: 188 SAMEEGNFLTKYGSQVYIIHRRNTF--RASKIMQA---RALSNPKIQVVWDSEVVEAYGG 242 Query: 264 -VEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQ 322 + K+K + S V L + IG + N ++L++ + Sbjct: 243 AGGGPLAGVKVKNLVTGEVSDLQVSGLFFAIGHEPATKFL--NGQLELHADGYVATKPGS 300 Query: 323 -NTNVPNIYSLGDVVGK 338 +T+V +++ GDV K Sbjct: 301 THTSVEGVFAAGDVQDK 317 >4FK1-A nrPDB Length = 304 Score = 59.1 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 60/352 (17%), Positives = 110/352 (31%), Gaps = 70/352 (19%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD 77 S K+ D VIG G G+ ++ + L + Sbjct: 1 SNAMKYIDCAVIGAGPAGLNASLVLGRARKQIALFDNNT--------------------- 39 Query: 78 LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG 137 RV+ N +G + E + ++ V Sbjct: 40 NRNRVTQ-NSHGFITRDGIKPEEFK-----------------EIGLNEVMKYPSVHYYEK 81 Query: 138 WARFNKDGN---VEVQKRDNTTEVYSANHILVATGGKAIFPENIPGF-ELGTDSD----- 188 + E+ +D+T Y A +L+ATG + FP IP E S Sbjct: 82 TVVMITKQSTGLFEIVTKDHTK--YLAERVLLATGMQEEFPS-IPNVREYYGKSLFSCPY 138 Query: 189 -GFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVI--RGETVLRKFDECIQNTIT 245 + L++QP ++++ + T LV + V+ + TI Sbjct: 139 CDGWELKDQP--LIII---------SENEDHTLHMTKLVYNWSTDLVIATNGNELSQTIM 187 Query: 246 DHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSEN 305 D + I V S + K++ H I+ I + + + E Sbjct: 188 DELSNKNIPVITESIRTLQGEGGYLKKVEFH--SGLRIERAGGFIVPTFFRPNQFI--EQ 243 Query: 306 VGIKLNSHDQIIADEYQNTNVPNIYSLGD-VVGKVELTPVAIAAGRKLSNRL 356 +G +L S+ + D++ T+ NIY G+ +A + G K + + Sbjct: 244 LGCELQSNGTFVIDDFGRTSEKNIYLAGETTTQGPSSLIIAASQGNKAAIAI 295 >1Y56-A nrPDB Length = 493 Score = 55.7 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 45/242 (18%), Positives = 83/242 (34%), Gaps = 44/242 (18%) Query: 95 PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDN 154 + +E + + + V +LN + LE + V F V V + D Sbjct: 150 GIKQEGFNKDSRKVVE---ELVGKLNENTKIYLETSALGVFDKGEYFL----VPVVRGDK 202 Query: 155 TTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAG 214 E+ A +++ATG DS F + P V +E+ Sbjct: 203 LIEIL-AKRVVLATGA--------------IDSTMLFENNDMPG----VFRRDFALEVMN 243 Query: 215 VF-HGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKL 273 V+ G + + + + + GI+ + + +VE N + +++ Sbjct: 244 VWEVAPGRKVAVTGSK-----------ADEVIQELERWGIDYVHIPNVKRVEGNEKVERV 292 Query: 274 KIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQ--IIADEYQNTNVPNIYS 331 I MN+ + VD LI+ GR+ + ++ G + DEY IY Sbjct: 293 -IDMNNHE--YKVDALIFADGRRPDINPITQAGGKLRFRRGYYSPVLDEYHRIK-DGIYV 348 Query: 332 LG 333 G Sbjct: 349 AG 350 >5NMX-A nrPDB Length = 425 Score = 54.9 bits (131), Expect = 9e-08, Method: Composition-based stats. Identities = 55/317 (17%), Positives = 97/317 (30%), Gaps = 70/317 (22%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVGCVPKKVMWYASDLATRVSH 84 V+G G G+ +AR G + ++ E +GGT W +D Sbjct: 4 VAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGGT------------WNYTDETWMSED 51 Query: 85 ANEYGLYQNLPLDKEHLTFNWPE-FKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 ++L N P+ D H + G Y KE + + Sbjct: 52 GRP-----VYSSMYQNLFVNLPKELMAFPDFPFHDIEGSYV--PSKEVLKYFDNFTDAFD 104 Query: 144 -------DGNVE----------VQKRDNTT---EVYSANHILVATGGK--AIFPENIPGF 181 +VE V D TT + + ++V TG ++P ++ G Sbjct: 105 LRKLIKLQHHVENVRPCESGWLVTVTDLTTMVEHSFEFDAVVVCTGQTWCPLYP-DVEGR 163 Query: 182 ELG---TDSDGFFRLEEQ--PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKF 236 FR E K+V++VGAG G ++A + E Sbjct: 164 SFFRGRLTHAHEFRSPEPFRNKRVLIVGAGPSGHDMALHISYVSKEV------------- 210 Query: 237 DECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRK 296 + + + + + H +D S DVDE+++ G + Sbjct: 211 -------FLSRKELKPVEGLFPDNVTEKPLLTSLSEYTAHFSDGTST-DVDEILYCTGYR 262 Query: 297 SHLGMGSENVGIKLNSH 313 S G+ ++ Sbjct: 263 YRFPFLSPECGVTVDEK 279 Score = 33.7 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 ++V V+GAG G+ A G E + R V Sbjct: 2 RRVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHV 36 >4OVI-A nrPDB Length = 542 Score = 53.7 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 41/246 (16%), Positives = 79/246 (32%), Gaps = 29/246 (11%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDL 78 + D LV+G G G+ + R G ++E +GG W Sbjct: 13 PPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGGV----------WYWNRYPG 62 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFG- 137 A + EY + + +E +NW E + + +N + K + + Sbjct: 63 ARCDIESIEYCYSFSEEVLQE---WNWTERYASQPEILRYINFVADKFDLRSGITFHTTV 119 Query: 138 WARFNKDGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPGF-ELGTDSDGFFRLE 194 A + N + A ++++A+G P N PG + + Sbjct: 120 TAAAFDEATNTWTVDTNHGDRIRARYLIMASGQLSVPQLP-NFPGLKDFAGNLYHTGNWP 178 Query: 195 EQP-----KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-----RKFDECIQNTI 244 +P ++V V+G G GI+++ +E + R D + Sbjct: 179 HEPVDFSGQRVGVIGTGSSGIQVSPQIAKQAAELFVFQRTPHFAVPARNAPLDPEFLADL 238 Query: 245 TDHYVK 250 Y + Sbjct: 239 KKRYAE 244 >3UP5-A nrPDB Length = 545 Score = 52.2 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 45/254 (17%), Positives = 74/254 (29%), Gaps = 51/254 (20%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLATRVS 83 D +VIG G G+ A G K L +EA +GGT W + Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGT----------WYWNRYPGCRLDT 60 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWAR--- 140 + YG + + E + W E + R ++ K Sbjct: 61 ESYAYGYFALKGIIPE---WEWSENFAS-QPEMLRYVNRAADAMDVRKHYRFNTRVTAAR 116 Query: 141 -FNKDGNVEVQKRDNTTEVYSANHILVATGG---------------------KAIFPENI 178 D EV + EV + ++ ATG + +P + Sbjct: 117 YVENDRLWEVTL--DNEEVVTCRFLISATGPLSASRMPDIKGIDSFKGESFHSSRWPTDA 174 Query: 179 PGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET-VLRKFD 237 G G D G K+V V+G G G+++ + E ++ R + Sbjct: 175 EGAPKGVDFTG--------KRVGVIGTGATGVQIIPIAAETAKELYVFQRTPNWCTPLGN 226 Query: 238 ECIQNTITDHYVKE 251 + D Sbjct: 227 SPMSKEKMDSLRNR 240 >1NAA-A nrPDB Length = 541 Score = 50.7 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 5/42 (11%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-----LGGT 60 YDY+++G G GG+ +A R + G K LL+E GGT Sbjct: 3 YDYIIVGAGPGGIIAADRLSEAGKKVLLLERGGPSTKQTGGT 44 >3H8L-A nrPDB Length = 409 Score = 49.5 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 55/161 (34%), Gaps = 18/161 (11%) Query: 221 SETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDS 280 + GE L + + Y + GI + KI ++ ++ D + Sbjct: 202 VHVTVFSPGE-YLSDLSPNSRKAVASIYNQLGIKLVHNFKIKEIREHEIVD-------EK 253 Query: 281 KSIDDVDELIWTIGRKSHLG-MGSENVGIKL-NSHDQIIADEYQNT-NVPNIYSLGDVVG 337 + D I + G +N L + I D + N+Y++GD Sbjct: 254 GNTIPADITIL---LPPYTGNPALKNSTPDLVDDGGFIPTDLNMVSIKYDNVYAVGDANS 310 Query: 338 --KVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 +L +A+ GR + L K+D + P+++ Sbjct: 311 MTVPKLGYLAVMTGRIAAQHLANRLGVPT-KVD-KYYPTIV 349 Score = 36.4 bits (83), Expect = 0.032, Method: Composition-based stats. Identities = 16/119 (13%), Positives = 45/119 (37%), Gaps = 20/119 (16%) Query: 199 KVVVVGAGYIGIELAGVFHGL---GSETHLV------IRGETV------LRKFDECIQNT 243 KV+V+G + + A L ++ ++ + +R D ++ Sbjct: 3 KVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVD-ELKVD 61 Query: 244 ITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS-IDDVDELIWTIGRKSHLGM 301 +++ ++GI + + + K+ + ++ + D ++ D +I IG + Sbjct: 62 LSEALPEKGIQFQEGT-VEKI--DAKSSMVYYTKPDGSMAEEEYDYVIVGIGAHLATEL 117 >4USR-A nrPDB Length = 361 Score = 49.1 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 59/351 (16%), Positives = 114/351 (32%), Gaps = 78/351 (22%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYASDLATRVS 83 D +VIGGG + +A LL++ + GG ++ W + L + + Sbjct: 9 DVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGGAWLHA--------WDSLRLFSPAA 60 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNK 143 ++ G P + + T N Y R Q+ + + V + R Sbjct: 61 WSSIAGWPMPSPTEPGNPTRND--VIDYLRRYEDRYQFPIQRPVRVDTVTRLDDLWRV-- 116 Query: 144 DGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPGFELGTDS---DGFFRLEEQ-- 196 + + A ++ ATG K P G EL + +R Sbjct: 117 --------QAGDQQWL-ARAVISATGTWSKPFIPPY-EGRELFQGAQIHSAHYRTPAPFA 166 Query: 197 PKKVVVVGAGYIGIELAGVFHGLGS-----------------ETH---LVIRG------- 229 K+V+VVG G G A V L S E L R Sbjct: 167 GKRVMVVGGGNSG---AQVLAELSSVSETLWITQEPPAFLPDEVDGRVLFERATARWKAQ 223 Query: 230 ------ETVLRKF-DECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS 282 + F D + + + + G+ + + + + D + Sbjct: 224 QEGRSIDEPAGGFGDIVMVPPVREA-RERGV-LVAERPFARFTETG------VEWADGR- 274 Query: 283 IDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLG 333 +++D +IW G + L +G+ + + ++ ++ + PN++ +G Sbjct: 275 RENLDAVIWCSGFRPALD-HLRELGV-VEADGKVQVEDTRVVKQPNLWLVG 323 >4C5O-A nrPDB Length = 357 Score = 49.1 bits (116), Expect = 4e-06, Method: Composition-based stats. Identities = 51/333 (15%), Positives = 99/333 (29%), Gaps = 62/333 (18%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLA 79 D +VIGGG G+++ G ++++A+A GG W + + Sbjct: 1 MDSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGGA------------WQHAWHS 48 Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQK-NLEKEKVDVVFGW 138 + + P+ + + + AY+ + Y L +V V + Sbjct: 49 LHLFSPAGWSSIPGWPMPASQGPY---PARAEVLAYLAQYEQKYALPVLRPIRVQRVSHF 105 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATGGK-AIFPENIPGFE----LGTDSDGFFRL 193 + V RD + A ++ ATG + G E + S + Sbjct: 106 GE-----RLRVVARDGRQ--WLARAVISATGTWGEAYTPEYQGLESFAGIQLHSAHYSTP 158 Query: 194 EEQPK-KVVVVGAGYIGIELAGVFHGLG--SETHLVIRGETVLRKFDECIQNTITDHYVK 250 +V ++G G G A + + +ET + R E D + + Sbjct: 159 APFAGMRVAIIGGGNSG---AQILAEVSTVAETTWITRTEPAFLADDVDGRVLFERATER 215 Query: 251 -----EG-------------------INVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDV 286 EG ++ + V + D Sbjct: 216 WKAQQEGREPDLPPGGFGDIVMVPPVLDARARGVLAAVPPPARFSPTGMQWADGTER-AF 274 Query: 287 DELIWTIGRKSHLGMGSENVGIKLNSHDQIIAD 319 D +IW G + L + + + + Q+ D Sbjct: 275 DAVIWCTGFRPALS-HLKGLDL-VTPQGQVEVD 305 >1PS9-A nrPDB Length = 671 Score = 48.7 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 45/319 (14%), Positives = 91/319 (28%), Gaps = 103/319 (32%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGTCVNVGCVPKKVMWYASDLATRVSH 84 V+G G G+A A AA+ G + L +A +GG Sbjct: 376 LAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGG------------------------- 410 Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKD 144 FN + ++ + L Y++ +E V + Sbjct: 411 -----------------QFNIAKQIPGKEEFYETLRY-YRRMIEVTGVT-------LKLN 445 Query: 145 GNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFEL--GTDSDGFFRLEEQPK-KVV 201 V ++ + + ++A+G P I G + R + KV Sbjct: 446 HTVTAD------QLQAFDETILASGIVPRTPP-IDGIDHPKVLSYLDVLRDKAPVGNKVA 498 Query: 202 VVGAGYIGIE---------------LAGVFHGLGSETHL------------VIRGETVLR 234 ++G G IG + +AG + G ++ L + R + Sbjct: 499 IIGCGGIGFDTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIV 558 Query: 235 KFDECIQNTITD-----------HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSI 283 + G+ + K+ + D L + +N + Sbjct: 559 MLQRKASKPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKI----DDDGLHVVINGETQV 614 Query: 284 DDVDELIWTIGRKSHLGMG 302 VD ++ G++ + + Sbjct: 615 LAVDNVVICAGQEPNRALA 633 Score = 41.0 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 16/113 (14%), Positives = 26/113 (23%), Gaps = 28/113 (24%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD-----------ECIQNTITD 246 K + VVGAG G+ A G + L + +F+ Sbjct: 374 KNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRR 433 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL 299 G+ + + + DE I G Sbjct: 434 MIEVTGVTLKLNHTVTA-----------------DQLQAFDETILASGIVPRT 469 >6ER9-A nrPDB Length = 549 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 43/220 (19%), Positives = 75/220 (34%), Gaps = 30/220 (13%) Query: 25 DYLVIGGGSGGVASARRA-ASYGAKTLLVEA-KALGGTCVNVGCVPKKVMW--YASDLAT 80 D +VIG G GG+ + + G + + GGT W Y L+ Sbjct: 11 DAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGGT----------WYWNRYPGALSD 60 Query: 81 RVSHANEYGLYQNLPLDKE--HLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 SH + ++L D PE + ++ V R + E ++ Sbjct: 61 TESHLYRFSFDRDLLQDGTWKTTYITQPEILEYLESVVDRFDLRRHFRFGTEVTSAIY-- 118 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPGFE-LGTDSDGFFRLEE 195 + EV + EVY A +++ A G FP ++PG + ++ E Sbjct: 119 --LEDENLWEVST--DKGEVYRAKYVVNAVGLLSAINFP-DLPGLDTFEGETIHTAAWPE 173 Query: 196 ----QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 K+V V+G G G ++ + +R Sbjct: 174 GKNLAGKRVGVIGTGSTGQQVITALAPEVEHLTVFVRTPQ 213 >2TMD-A nrPDB Length = 729 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 58/374 (15%), Positives = 112/374 (29%), Gaps = 92/374 (24%) Query: 15 RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGGTCVNVGCVPKKVMW 73 + T K L++G G G +AR G L + A+ +GG Sbjct: 382 KFRQTKNKD-SVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGG-------------- 426 Query: 74 YASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEK-V 132 L + + K L+K K Sbjct: 427 ---HLNQVAALPGLGEWSY----------------------HRDYRETQITKLLKKNKES 461 Query: 133 DVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGK-------AIFPENIPGFELG- 184 + G D ++ Y A+ +++ATG + + + IPG + Sbjct: 462 QLALGQKPMTADDVLQ----------YGADKVIIATGARWNTDGTNCLTHDPIPGADASL 511 Query: 185 ---TDSDGFFR-LEEQPKKVVVVGAG--YIGIELAGVFHGLGSETHLVIRGE-----TVL 233 + ++ K+VV++ A ++ LA G E +V Sbjct: 512 PDQLTPEQVMDGKKKIGKRVVILNADTYFMAPSLAEKLATAGHEVTIVSGVHLANYMHFT 571 Query: 234 RKFDECIQNTITDHYVKEGINVHKLSKIVKVEKN---VETDKLKI--------HMNDSKS 282 ++ ++ H + G + + ++E + K N S Sbjct: 572 LEYPNMMRRLHELHVEELGDHFCSRIEPGRMEIYNIWGDGSKRTYRGPGVSPRDANTSHR 631 Query: 283 IDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGKVELT 342 + D L+ GR S + +E L + + E+ ++ IY +GD L Sbjct: 632 WIEFDSLVLVTGRHSECTLWNE-----LKARES----EWAENDIKGIYLIGD-AEAPRLI 681 Query: 343 PVAIAAGRKLSNRL 356 A G +++ + Sbjct: 682 ADATFTGHRVAREI 695 >4TLZ-A nrPDB Length = 443 Score = 46.4 bits (109), Expect = 3e-05, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 41/119 (34%), Gaps = 10/119 (8%) Query: 123 YQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFE 182 ++ + + E + G R V+V + T A +I+++TG P + E Sbjct: 139 HEVSYDSEVTAIRPGPGRPVDSVLVDVSTPE-ATRTVEARNIVISTGLVPRMPAGVQSDE 197 Query: 183 LGTDSDGFFR-----LEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKF 236 S F ++V V G G E+ H +T + ++ + Sbjct: 198 FVWHSSRFLDHFRDRDPRSLRRVAVAGGGQSAAEIVRFLHDNRPDTVV----HAIMPSY 252 >2VOU-A nrPDB Length = 397 Score = 46.0 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 29/74 (39%), Gaps = 2/74 (2%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQN--TITDHYVKEGINV 255 ++ VVG G+ A + G + + R L F I + + +++G+ + Sbjct: 6 DRIAVVGGSISGLTAALMLRDAGVDVDVYERSPQPLSGFGTGIVVQPELVHYLLEQGVEL 65 Query: 256 HKLSKIVKVEKNVE 269 +S + V+ Sbjct: 66 DSISVPSSSMEYVD 79 >6A37-A nrPDB Length = 552 Score = 45.6 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 40/227 (17%), Positives = 75/227 (33%), Gaps = 32/227 (14%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAAS-YGAKTLLVEAKA-LGGTCVNVGCVPKKVMW--Y 74 T +D ++IG G GG+ S ++ + K + +GGT W Y Sbjct: 22 TQKMDFDAIIIGAGFGGLYSLKKLRDDFNLKVRAFDRATEVGGT----------WFWNQY 71 Query: 75 ASDLATRVSHANEYGLYQNL--PLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 L+ +H Y + L ++ + + P+ + +L K+ + Sbjct: 72 PGALSDSETHLYCYSWDKELLQEMEIKRKYISQPDVLAYLKRVAD------KHDLRKD-I 124 Query: 133 DVVFG-WARFNKDGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPGFE-----LG 184 G + + + N E ++A ++ A G P I G E L Sbjct: 125 QFETGIRSAYFDEENSFWNVTTENDEKFTARFLITALGLLAAPNLP-KIKGIETFKGELH 183 Query: 185 TDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 S + K+V V+G G G+++ + R Sbjct: 184 HTSRWPKDVTFSGKRVGVIGTGSTGVQVITAIASQVKHLTVFQRSAQ 230 >4B68-A nrPDB Length = 501 Score = 45.6 bits (107), Expect = 5e-05, Method: Composition-based stats. Identities = 39/244 (15%), Positives = 73/244 (29%), Gaps = 81/244 (33%) Query: 129 KEKVDVVFGWA----RFNKDGNVEVQKRDNTT-EVYSANHILVATGGKAIFPENIP---- 179 +E V+V+ G + V + + +++A GG A P +P Sbjct: 166 EEVVEVIPGKSDPSSSVVDFFTVRSRNVETGEISARRTRKVVIAIGGTAKMPSGLPQDPR 225 Query: 180 ---GFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGL-----GSETHLVIRGET 231 + T + + +P + V+G+G E +FH L S T L++R Sbjct: 226 IIHSSKYCTTLPALLKDKSKPYNIAVLGSGQSAAE---IFHDLQKRYPNSRTTLIMRDSA 282 Query: 232 VLRKFDE----------------------------------------CIQNTITDHYVKE 251 + D + I + + Sbjct: 283 MRPSDDSPFVNEIFNPERVDKFYSQSAAERQRSLLADKATNYSVVRLELIEEIYNDMYLQ 342 Query: 252 GIN----------VHKLSKIVKVEKNVETDKLKIHM-----------NDSKSIDDVDELI 290 + + KI +VE + +++IH+ ND K +VD L+ Sbjct: 343 RVKNPDETQWQHRILPERKITRVEHHGPQSRMRIHLKSSKPESEGAANDVKETLEVDALM 402 Query: 291 WTIG 294 G Sbjct: 403 VATG 406 >4RG3-A nrPDB Length = 548 Score = 45.3 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 44/231 (19%), Positives = 80/231 (34%), Gaps = 35/231 (15%) Query: 17 MSTNTKHY-DYLVIGGGSGGVASARRA-ASYGAKTLLVEA-KALGGTCVNVGCVPKKVMW 73 M+ T H D +VIG G GG+ + + G T+ + GGT W Sbjct: 9 MTAQTTHTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGT------------W 56 Query: 74 YASDLATRVSHANEYGLYQNLPLDK------EHLTFNWPEFKQKRDAYVHRLNGIYQKNL 127 Y + +S + + D + PE + + V R + +++ Sbjct: 57 YWNRYPGALSDTESHLYRFSFDRDLLQESTWKTTYITQPEILEYLEDVVDRFD--LRRHF 114 Query: 128 EKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPGFE-LG 184 + V + + EV + EVY A +++ A G FP N+PG + Sbjct: 115 KFG--TEVTSALYLDDENLWEVTT--DHGEVYRAKYVVNAVGLLSAINFP-NLPGLDTFE 169 Query: 185 TDSDGFFRLEE----QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 ++ E ++V V+G G G ++ + +R Sbjct: 170 GETIHTAAWPEGKSLAGRRVGVIGTGSTGQQVITSLAPEVEHLTVFVRTPQ 220 >6JDK-A nrPDB Length = 544 Score = 45.3 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 45/246 (18%), Positives = 77/246 (31%), Gaps = 32/246 (13%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGG----TCVNVGCVPKKVMWYASDL 78 +D L++G G G+ R G K L EA A +GG C V + Y + Sbjct: 18 FDALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGGIWYWNCYPGARVDSHIPIYEFSI 77 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW 138 + + P + L + +K D L+ + + + Sbjct: 78 EELWRD---WNWTERFPA-WDELRRYFHYVDKKLD-----LSRDIRFGMRVSAAEFDEAR 128 Query: 139 ARFNKDGNVEVQKRDNTTEVYSANHILVATG--GKAIFPENIPGFE-LGTDS--DGFFRL 193 ++ D T V A ++ TG K P N G E +S G + Sbjct: 129 ------DQWVIRTTDGT--VVRARFFILCTGFASKPYIP-NYKGLESFAGESFHTGLWPQ 179 Query: 194 EE---QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV-LRKFDECIQNTITDHYV 249 E K+V VVG G G+++ + + R + L + Sbjct: 180 EGASFTGKRVGVVGTGASGVQVVQEASKDAAHLTVFQRTPILALPMQQRKLDVETQQRMK 239 Query: 250 KEGINV 255 + + Sbjct: 240 ADYPEI 245 >3KVE-A nrPDB Length = 486 Score = 44.9 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 22/50 (44%) Query: 182 ELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 E + + PK VVVVGAG G+ A V G G + ++ E Sbjct: 18 EFLEIARNGLKKTSNPKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASER 67 Score = 40.6 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 99/299 (33%), Gaps = 57/299 (19%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGG---TCVNVGCVPKKVMW 73 ++N KH +V+G G G+++A A G K ++EA + GG T N K W Sbjct: 30 TSNPKH--VVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRN-----SKEGW 82 Query: 74 YASD--------LATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ- 124 YA+ + ++GL N + + + + +KR V++ G+ + Sbjct: 83 YANLGPMRIPEKHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVNKDPGLLKY 142 Query: 125 -----KNLEKEKVDVVFGWAR-FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENI 178 + + N + YS L+ G + ++ Sbjct: 143 PVKPSEEGKSAGQLYEESLGSAVKDLKRTNCSYILNKYDTYSTKEYLIKEGNLSPGAVDM 202 Query: 179 PGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVI---RGETVLRK 235 G L DS GY L + + R + ++ Sbjct: 203 IGDLLNEDS------------------GY----YVSFIESLKHD-DIFAYEKRFDEIVGG 239 Query: 236 FDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMND-SKSIDDVDELIWTI 293 D+ + ++ + V ++++K+++N + + S + D +I Sbjct: 240 MDQ-LPTSMYRAIEE---KVKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVCT 294 >3NIX-A nrPDB Length = 421 Score = 44.9 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 59/182 (32%), Gaps = 36/182 (19%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDL 78 + D LVIG G G +A G K +VE + P + + S L Sbjct: 1 MQREKVDVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKF----------P-RFVIGESLL 49 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKR--------DAYVHRLNGIY---QKNL 127 + H +E G + F +F + + D + + N + + N Sbjct: 50 PRCMEHLDEAGFLDAVKAQGFQQKFG-AKFVRGKEIADFNFSDQFSNGWNWTWQVPRGNF 108 Query: 128 EK--------EKVDVVFGWAR-----FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIF 174 +K + VDV + F D ++ + A I+ A+G + Sbjct: 109 DKTLADEAARQGVDVEYEVGVTDIKFFGTDSVTTIEDINGNKREIEARFIIDASGYGRVI 168 Query: 175 PE 176 P Sbjct: 169 PR 170 Score = 29.1 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 34/79 (43%), Gaps = 9/79 (11%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIR--------GETVLRK-FDECIQNTITDHYVK 250 V+V+GAG G A + + G + +V + GE++L + + + D Sbjct: 8 VLVIGAGPAGTVAASLVNKSGFKVKIVEKQKFPRFVIGESLLPRCMEHLDEAGFLDAVKA 67 Query: 251 EGINVHKLSKIVKVEKNVE 269 +G +K V+ ++ + Sbjct: 68 QGFQQKFGAKFVRGKEIAD 86 >5BR7-A nrPDB Length = 393 Score = 44.9 bits (105), Expect = 8e-05, Method: Composition-based stats. Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 21 TKHYDYLVIGGGSGGVASARRAA-SYGAKTLLVEAKA-LGGT 60 +D +V+G G G+ A RAA G K L+VE ++ LGG Sbjct: 1 MSDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGN 42 >6CR0-A nrPDB Length = 440 Score = 44.5 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 1/43 (2%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 + K YD +V+G G G+ +AR ++ G L++E LGG Sbjct: 3 AMTEKIYDAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGG 45 >1REO-A nrPDB Length = 486 Score = 44.5 bits (104), Expect = 9e-05, Method: Composition-based stats. Identities = 16/50 (32%), Positives = 22/50 (44%) Query: 182 ELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 E + + PK VVVVGAG G+ A V G G + ++ E Sbjct: 18 EFLEIARNGLKATSNPKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASER 67 Score = 39.1 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 44/296 (14%), Positives = 98/296 (33%), Gaps = 51/296 (17%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCV------------NVG 65 ++N KH +V+G G G+++A + G + ++EA G V N+G Sbjct: 30 TSNPKH--VVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLG 87 Query: 66 CVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ- 124 P M + ++GL N + + + + +KR V + G+ + Sbjct: 88 --P---MRLPEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVKKDPGVLKY 142 Query: 125 -----KNLEKEKVDVVFGWARFNKD-GNVEVQKRDNTTEVYSANHILVATGGKAIFPENI 178 + + + ++ N + YS L+ G + ++ Sbjct: 143 PVKPSEEGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLLKEGNLSPGAVDM 202 Query: 179 PGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDE 238 G + DS + E + + E R + ++ D+ Sbjct: 203 IGDLMNEDSGYYVSFPESLRHDDIF-----AYE---------------KRFDEIVGGMDK 242 Query: 239 CIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS-IDDVDELIWTI 293 + ++ + VH ++++K++KN E + + D +I Sbjct: 243 -LPTSMYRAIEE---KVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTADYVIVCT 294 >1F8S-A nrPDB Length = 498 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 22/51 (43%) Query: 182 ELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 E + + PK VV+VGAG G+ A V G G + ++ E Sbjct: 18 EFLEIARNGLKATSNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERP 68 Score = 37.6 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 42/299 (14%), Positives = 95/299 (31%), Gaps = 57/299 (19%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTC-----------VNVG 65 ++N KH +++G G G+++A A G + ++EA + GG N+G Sbjct: 30 TSNPKH--VVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANLG 87 Query: 66 CVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ- 124 P M + ++ L N + + + + +K+ V + G+ + Sbjct: 88 --P---MRLPEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKY 142 Query: 125 -----KNLEKEKVDVVFGWARFNKD-GNVEVQKRDNTTEVYSANHILVATGGKAIFPENI 178 + + + ++ N + YS L+ G + Sbjct: 143 PVKPSEAGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEG------DLS 196 Query: 179 PGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVI---RGETVLRK 235 PG + +GY L + + R + ++ Sbjct: 197 PGAVDMIG--DLLNED----------SGY----YVSFIESLKHD-DIFAYEKRFDEIVDG 239 Query: 236 FDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKS-IDDVDELIWTI 293 D+ D K VH ++++K+++N + + ++ D +I Sbjct: 240 MDKLPTAMYRDIQDK----VHFNAQVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCT 294 >5J7X-A nrPDB Length = 549 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 45/236 (19%), Positives = 74/236 (31%), Gaps = 45/236 (19%) Query: 18 STNTKHYDYLVIGGG-SGGVASARRAASYGAKTLLVEAKA-LGGTCVN-------VGC-V 67 S H D L+IG G SG + K + EA++ +GGT N V C V Sbjct: 7 SNGVLHLDALIIGSGFSGIYLLHKLRDELKLKVKIFEAESDIGGTWNNNRYPGARVDCPV 66 Query: 68 PKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNL 127 P + L + ++NW E + + L Sbjct: 67 P----------------------FYAYSLPEVWQSWNWTELYPN-QKEIKSYFDHVDRVL 103 Query: 128 EKEKVDVVFG---WARFNKDGNVEVQKRDNTTEVYSANHILVATG-GKAIFPENIPGFE- 182 + K + F + +V +A ++LVA G + + G + Sbjct: 104 DVRKDCLFHSRVNEGTF-DEATGRWTVWTTDGKVATAKYLLVAVGFASKSYLPDWKGLDS 162 Query: 183 ------LGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 + + KKV V+G G GI++ + E L R + Sbjct: 163 FKGTIYHSAHWPEAEEISVKGKKVAVIGTGSTGIQIFQEWAREAEEAFLFQRTPNL 218 >3BHF-A nrPDB Length = 390 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 16/35 (45%), Positives = 24/35 (68%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 + H+D +V+G GS G+A+ + A G KTLLV+A Sbjct: 1 MSTHFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDA 35 >3K30-A nrPDB Length = 690 Score = 43.7 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 60/350 (17%), Positives = 100/350 (28%), Gaps = 96/350 (27%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLATRVSH 84 LV+G G G+ +AR G +L EA LGG Sbjct: 394 VLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGG--------------------RVTQE 433 Query: 85 ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKD 144 + GL W K+ R+A + L V++ + D Sbjct: 434 SALPGLSA------------WGRVKEYREAVLAEL----------PNVEIYR-ESPMTGD 470 Query: 145 GNVEVQKRDNTTEVYSANHILVATGG-------KAIFPENIPGFELG--TDSDGFFRLEE 195 VE + H++ ATG +P E D F Sbjct: 471 DIVE----------FGFEHVITATGATWRTDGVARFHTTALPIAEGMQVLGPDDLFAGRL 520 Query: 196 QPKKVVVVG-------AGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECI-QNTITDH 247 K VVV G + A + G E +V G V + N I Sbjct: 521 PDGKKVVVYDDDHYYLGGVV----AELLAQKGYEVSIVTPGAQVSSWTNNTFEVNRIQRR 576 Query: 248 YVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVG 307 ++ G+ +V V T + + + D ++ R + + V Sbjct: 577 LIENGVARVTDHAVVAVGAGGVTVRD--TYASIERELECDAVVMVTARLPREELYLDLVA 634 Query: 308 IKLNSHDQIIADEYQNTNVPNI---YSLGDVVGKVELTPVAIAAGRKLSN 354 + D + +V I ++ G + A+ +GR+ + Sbjct: 635 RR---------DAGEIASVRGIGDAWAPGTIA-------AAVWSGRRAAE 668 Score = 37.2 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 43/130 (33%), Gaps = 9/130 (6%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 +E +V+VVGAG G+E A G + L G + + + + + + Sbjct: 388 KESDARVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRVTQESALPGLSAWGR--V 445 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSH 313 ++ + + ++ NVE + D + +I G G+ Sbjct: 446 KEYREAVLAEL-PNVEIYRESPMTGDDIVEFGFEHVITATGATWRTD------GVARFHT 498 Query: 314 DQIIADEYQN 323 + E Sbjct: 499 TALPIAEGMQ 508 >1ZOV-A nrPDB Length = 386 Score = 43.7 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 22/33 (66%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVE 53 + H+D +V+G GS G+A+ A G KTLLV+ Sbjct: 1 STHFDVIVVGAGSMGMAAGYYLAKQGVKTLLVD 33 Score = 28.3 bits (62), Expect = 7.0, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 V+VVGAG +G+ G +T LV + Sbjct: 6 VIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPP 38 >3RHA-A nrPDB Length = 482 Score = 43.3 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 M D +++G G G+ +AR G ++E +GG Sbjct: 1 MVMQNLDRDVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGG 44 Score = 32.6 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 17/39 (43%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 + + VV+VGAG G+ A G ++ + V Sbjct: 4 QNLDRDVVIVGAGPSGLTAARELKKAGLSVAVLEARDRV 42 >2BXR-A nrPDB Length = 527 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 +D +VIGGG G+++A+ YG L++E +GG Sbjct: 14 FDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGG 50 Score = 35.2 bits (80), Expect = 0.059, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 15/33 (45%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 VVV+G G G+ A + G ++ + V Sbjct: 16 VVVIGGGISGLSAAKLLTEYGVSVLVLEARDRV 48 >3MJ4-A nrPDB Length = 397 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 1/42 (2%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGGT 60 +K +DYL++G G G A R AS G + L+V+ + +GG Sbjct: 26 ESKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGN 67 Score = 29.1 bits (64), Expect = 4.7, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 15/32 (46%) Query: 201 VVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 ++VGAG+ G LA G +V R + Sbjct: 33 LIVGAGFAGSVLAERLASSGQRVLIVDRRPHI 64 >1O5W-A nrPDB Length = 534 Score = 42.6 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 +D +VIGGG G+A+A+ + Y L++E +GG Sbjct: 22 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 58 Score = 33.3 bits (75), Expect = 0.26, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 14/33 (42%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 VVV+G G G+ A + ++ + V Sbjct: 24 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 56 >3T14-A nrPDB Length = 437 Score = 41.4 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 54/342 (15%), Positives = 114/342 (33%), Gaps = 97/342 (28%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHA 85 +++G G+GG+ +A +ALG + T +S Sbjct: 7 VVILGAGTGGMPAAYEM-----------KEALG----------------SGHEVTLISAN 39 Query: 86 NEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDG 145 + + + P + W E + + +E++ + + A Sbjct: 40 DYFQFVPSNPW----VGVGWKE--------RDDIAFPIRHYVERKGIHFIAQSAEQIDAE 87 Query: 146 NVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKV----- 200 + D T Y +++++ATG K F EN+PG + + ++ Sbjct: 88 AQNITLADGNTVHY--DYLMIATGPKLAF-ENVPGSDPHEGPVQSIATVDHAERAFAEYQ 144 Query: 201 --------VVVGAGYIGIELAGVFHGLG--SETHLVIRGETVLRKF-DE----------- 238 +V+GA +AG G E +++ + R D+ Sbjct: 145 ALLREPGPIVIGA------MAGA-SCFGPAYEYAMIVASDLKKRGMRDKIPSFTFITSEP 197 Query: 239 -----------CIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVD 287 + +T +EGI + K+ KVE N K+ + D K + Sbjct: 198 YIGHLGIQGVGDSKGILTKGLKEEGIEAYTNCKVTKVEDN----KMYVTQVDEKGETIKE 253 Query: 288 ELI---WTIGRKSHLGMGSENVGIK--LNSHDQIIADEYQNT 324 ++ + + + G+ + G++ N ++ DE+Q + Sbjct: 254 MVLPVKFGMMIPAFKGVPA-VAGVEGLCNPGGFVLVDEHQRS 294 >2ZXH-A nrPDB Length = 637 Score = 41.0 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 34/166 (20%), Positives = 58/166 (34%), Gaps = 22/166 (13%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTL--LVEAKALGGTCVNVGCVPKKVMWY 74 M+ +D +VIGGG G+ +A AA GAKT ++ A +G + C P Sbjct: 21 MAWVVDEFDVVVIGGGHAGIEAALAAARMGAKTAMFVLNADTIG----QMSCNPA---IG 73 Query: 75 ASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGI-----YQKNLEK 129 V + G +D+ + F ++ V Y++ ++K Sbjct: 74 GIAKGIVVREIDALGGEMGKAIDQTGIQF--KMLNTRKGKAVQSPRAQADKKRYREYMKK 131 Query: 130 ---EKVDVVFGWARFNK---DGNVEVQKRDNTTEVYSANHILVATG 169 + ++ N V R N Y ++V TG Sbjct: 132 VCENQENLYIKQEEVVDIIVKNNQVVGVRTNLGVEYKTKAVVVTTG 177 Score = 29.9 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 18/28 (64%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVI 227 VVV+G G+ GIE A +G++T + + Sbjct: 30 VVVIGGGHAGIEAALAAARMGAKTAMFV 57 >1I8T-A nrPDB Length = 367 Score = 41.0 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 31/92 (33%), Gaps = 5/92 (5%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLATRV 82 YDY+++G G G A K L++E + +GG C + Sbjct: 2 YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDC----EGIQIHKYGAHI 57 Query: 83 SHANEYGLYQNLPLDKEHLTFNWPEFKQKRDA 114 H N+ ++ + E F +D Sbjct: 58 FHTNDKYIWDYVNDLVEFNRFTNSPLAIYKDK 89 >4Y4M-A nrPDB Length = 290 Score = 40.6 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 1/51 (1%) Query: 5 TKQTFRSLQIRT-MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 TK T L+ M + D +++G G G+ AR A G K +++E Sbjct: 40 TKTTKAILKASFDMWLDIVEADVVIVGAGPSGLTCARYLAKEGFKVVVLER 90 Score = 32.6 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRG 229 VV+VGAG G+ A G + ++ R Sbjct: 62 VVIVGAGPSGLTCARYLAKEGFKVVVLERH 91 >4TXK-A nrPDB Length = 615 Score = 40.6 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEAK 55 LV+G G G+ +A A GA+ +LVE + Sbjct: 88 LVVGAGPCGLRAAVELALLGARVVLVEKR 116 Score = 29.9 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 15/29 (51%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVI 227 K +VVGAG G+ A LG+ LV Sbjct: 86 KCLVVGAGPCGLRAAVELALLGARVVLVE 114 >2BRY-A nrPDB Length = 497 Score = 40.6 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 18/29 (62%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEAK 55 LV+G G G+ +A A GA+ +LVE + Sbjct: 96 LVVGAGPCGLRAAVELALLGARVVLVEKR 124 Score = 29.9 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 15/29 (51%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVI 227 K +VVGAG G+ A LG+ LV Sbjct: 94 KCLVVGAGPCGLRAAVELALLGARVVLVE 122 >5EQD-A nrPDB Length = 400 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 21 TKHYDYLVIGGGSGGVASARRAA-SYGAKTLLVEAK-ALGGT 60 T ++D V+G G G+ A RAA G + L++E + +GG Sbjct: 2 TGNFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGN 43 >2GMH-A nrPDB Length = 584 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 12/58 (20%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARR----AASYGA--KTLLVEAKA------LGGTCV 62 M + D +++G G G+++A R AA + + LVE A L G C+ Sbjct: 29 MERFAEEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACL 86 >5AYV-A nrPDB Length = 309 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 25/133 (18%), Positives = 49/133 (36%), Gaps = 18/133 (13%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 ++ V+GAG IG + G++ L+ R E V + I + E V Sbjct: 2 RIYVLGAGSIGSLFGALLARAGNDVTLIGRREQV-----DAINKNGLHVFGAEEFTVKPK 56 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHL-------GMGSENVGIKLN 311 + I E+ + L + +K+ + IGR + G+G+E + +K Sbjct: 57 ATIYAPEEPPDLLILAVKSYSTKTALECAR--QCIGR--NTWVLSIQNGLGNEELALKYT 112 Query: 312 SH--DQIIADEYQ 322 + + + Sbjct: 113 PNVMGGVTTNGAM 125 >1QO8-A nrPDB Length = 566 Score = 39.9 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 22/48 (45%) Query: 12 LQIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGG 59 +Q + ++ LV+G GS G ++ A GA +LV+ G Sbjct: 110 IQKAIAAGPSETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSG 157 >4AP1-A nrPDB Length = 549 Score = 39.9 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 43/225 (19%), Positives = 76/225 (33%), Gaps = 30/225 (13%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGGTCVNVGCVPKKVMWYAS 76 +T T YD +V+G G G+ + R S G E A +GG W Sbjct: 16 TTGTTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGGV----------WYWNRY 65 Query: 77 DLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV-V 135 A + +Y + L++E +NW E + + L + + + + Sbjct: 66 PGARCDVESIDYSYSFSPELEQE---WNWSEKYATQPEILAYLEHVADRFDLRRDIRFDT 122 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP---GFELGTDSDGFFR 192 + + + R + + SA ++VA G + N P G + T Sbjct: 123 RVTSAVLDEEGLRWTVRTDRGDEVSARFLVVAAG--PLSNANTPAFDGLDRFTG--DIVH 178 Query: 193 LEEQP--------KKVVVVGAGYIGIELAGVFHGLGSETHLVIRG 229 P K+V V+G G GI+ + + + R Sbjct: 179 TARWPHDGVDFTGKRVGVIGTGSSGIQSIPIIAEQAEQLFVFQRS 223 Score = 28.3 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 17/64 (26%), Gaps = 10/64 (15%) Query: 169 GGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIR 228 G P GT S VVVVGAG G+ F G Sbjct: 3 GQHPRSVVTAPDATTGTTSYD----------VVVVGAGIAGLYAIHRFRSQGLTVRAFEA 52 Query: 229 GETV 232 V Sbjct: 53 ASGV 56 >4A7P-A nrPDB Length = 446 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 41/104 (39%), Gaps = 12/104 (11%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 ++ ++G GY+G+ F G E V D+ + + + + +++ Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHEVVCV----------DKDARKI--ELLHQNVMPIYEP 57 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMG 302 V NV+ +L + ++ + D D + +G S G G Sbjct: 58 GLDALVASNVKAGRLSFTTDLAEGVKDADAVFIAVGTPSRRGDG 101 >3ATQ-A nrPDB Length = 453 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 22/37 (59%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 YD L+IGGG G ++A + + G K LLV++K Sbjct: 2 MKELKYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSK 38 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 33/82 (40%), Gaps = 5/82 (6%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD-HYVKEG 252 +E V+++G G+ G A G + LV R D+ + ++ H+ K G Sbjct: 3 KELKYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKP-WNRIGDKPCGDAVSKAHFDKLG 61 Query: 253 INVHKLSKIVKVEKNVETDKLK 274 + K ++E + KL Sbjct: 62 MPYPKGE---ELENKINGIKLY 80 >2JB2-A nrPDB Length = 489 Score = 39.5 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGG 59 +V+GGG G+ SA G K ++EA+ GG Sbjct: 14 VVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGG 48 Score = 29.5 bits (65), Expect = 3.7, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 13/34 (38%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 VVV+G G G+ A G + ++ Sbjct: 13 SVVVLGGGPAGLCSAFELQKAGYKVTVLEARTRP 46 >3NK2-X nrPDB Length = 431 Score = 39.1 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 1/37 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAK-ALGG 59 YD +V+GGG G+ +AR + G K LL+E LGG Sbjct: 2 YDAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGG 38 Score = 32.2 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 17/32 (53%) Query: 201 VVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 +VVG G+ G++ A G + L+ GE + Sbjct: 5 IVVGGGFSGLKAARDLTNAGKKVLLLEGGERL 36 >4Z2R-A nrPDB Length = 592 Score = 39.1 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA 56 +N+ D L++G G G SA AS G ++L++ Sbjct: 8 SNSAETDVLIVGAGPAGAMSATLLASLGIRSLMINRWR 45 >2VHY-A nrPDB Length = 377 Score = 38.7 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVE 53 D +VIG G+ G +AR A GA +++ Sbjct: 170 DVVVIGAGTAGYNAARIANGMGATVTVLD 198 Score = 37.2 bits (85), Expect = 0.019, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 14/90 (15%) Query: 159 YSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHG 218 A H++ GG+ + +PG E P VVV+GAG G A + +G Sbjct: 144 VGAYHLMRTQGGRGVLMGGVPGVE--------------PADVVVIGAGTAGYNAARIANG 189 Query: 219 LGSETHLVIRGETVLRKFDECIQNTITDHY 248 +G+ ++ LR+ D I Y Sbjct: 190 MGATVTVLDINIDKLRQLDAEFCGRIHTRY 219 >3HYW-A nrPDB Length = 430 Score = 38.7 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 44/297 (14%), Positives = 93/297 (31%), Gaps = 47/297 (15%) Query: 82 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 +S +G P HL W +F ++ L K ++ + A Sbjct: 33 ISDRPYFGFTPAFP----HLAMGWRKF--------EDISVPLAPLLPKFNIEFINEKAES 80 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDS----DGFFRLEEQP 197 V + +++++ATG G E + S + +++ Sbjct: 81 IDPDANTVTTQSGKK--IEYDYLVIATG--PKLVFGAEGQEENSTSICTAEHALETQKKL 136 Query: 198 KKV------VVVGA--GYI----GIELAGVFH----GLGSETHL---VIRGETVLRKFD- 237 +++ VV+GA G E A + H G + I E L F Sbjct: 137 QELYANPGPVVIGAIPGVSCFGPAYEFALMLHYELKKRGIRYKVPMTFITSEPYLGHFGV 196 Query: 238 ---ECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIG 294 + + D + + I+ + +E + + +N + ++ Sbjct: 197 GGIGASKRLVEDLFAERNIDWIANVAVKAIEPD---KVIYEDLNGNTHEVPAKFTMFMPS 253 Query: 295 RKSHLGMGSENVGIKLNSHDQIIADE-YQNTNVPNIYSLGDVVGKVELTPVAIAAGR 350 + + S + ++ +I + +QN NI+ +G V + I G Sbjct: 254 FQGPEVVASAGDKVANPANKMVIVNRCFQNPTYKNIFGVGVVTAIPPIEKTPIPTGV 310 >3HDH-A nrPDB Length = 302 Score = 38.7 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 35/96 (36%), Gaps = 3/96 (3%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K V V+G G +G +A V G LV + E +L K + I+ ++ K + Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK---KFAE 72 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTI 293 K + + + + D ++ I Sbjct: 73 NPKAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAI 108 >4Y4N-A nrPDB Length = 286 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 M + D ++GGG G+ +AR A G K +++E Sbjct: 46 MWLDIIDVDVAIVGGGPSGLTAARYIAKEGYKVVVLER 83 Score = 30.2 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 18/130 (13%), Positives = 43/130 (33%), Gaps = 18/130 (13%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDEC--------IQNTITDHYVKE 251 V +VG G G+ A G + ++ R ++ + + Sbjct: 55 VAIVGGGPSGLTAARYIAKEGYKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADEILREV 114 Query: 252 GINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLN 311 G+ + K+ + D +++ + D G K G+ E++ ++ N Sbjct: 115 GVKL---EKVEGEDGLYTADSVEVPAKLAVGAIDA-------GAKVLTGIVVEDLVLREN 164 Query: 312 SHDQIIADEY 321 ++ + Y Sbjct: 165 RVAGVVINSY 174 >3ABT-A nrPDB Length = 662 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 17/35 (48%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 KV+++G+G G+ A G + L+ + V Sbjct: 108 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 142 Score = 36.0 bits (82), Expect = 0.036, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 ++IG G G+A+AR+ S+G L+E +GG Sbjct: 110 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 144 >5KXJ-A nrPDB Length = 557 Score = 38.3 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 7/22 (31%), Positives = 15/22 (68%) Query: 314 DQIIADEYQNTNVPNIYSLGDV 335 ++ D+Y T+V +Y++G+V Sbjct: 355 GGVVVDDYGRTDVDGLYAIGEV 376 Score = 35.2 bits (80), Expect = 0.069, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 16 TMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 M+T D L+IG G+ G++ A R A K +++ Sbjct: 1 MMTTPELSCDVLIIGSGAAGLSLALRLAEKH-KVIVLSKG 39 >5L3D-A nrPDB Length = 852 Score = 38.3 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 17/35 (48%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 KV+++G+G G+ A G + L+ + V Sbjct: 279 GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV 313 Score = 36.0 bits (82), Expect = 0.042, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 ++IG G G+A+AR+ S+G L+E +GG Sbjct: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG 315 >6C6P-A nrPDB Length = 458 Score = 37.9 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTIT 245 V++VGAG +G LA V G + ++ R L++ D + + Sbjct: 10 VIIVGAGVLGSALAAVLSRDGRKVTVIERD---LKEPDRIVGEFLQ 52 >2UZZ-A nrPDB Length = 372 Score = 37.9 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 YD ++IG GS G A+ A G L+ +A Sbjct: 2 KYDLIIIGSGSVGAAAGYYATRAGLNVLMTDA 33 >1C0L-A nrPDB Length = 363 Score = 37.9 bits (87), Expect = 0.010, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 19/31 (61%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIR 228 K+VVV+G+G IG+ A + G H++ R Sbjct: 7 KRVVVLGSGVIGLSSALILARKGYSVHILAR 37 >1F14-A nrPDB Length = 310 Score = 37.9 bits (87), Expect = 0.011, Method: Composition-based stats. Identities = 21/98 (21%), Positives = 37/98 (37%), Gaps = 7/98 (7%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 K V V+G G +G +A V G LV + E +L K + I+ ++ K Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKK-----KF 70 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKS--IDDVDELIWTI 293 ++ VE I + + + D ++ I Sbjct: 71 AENPKAGDECVEKTLSTIATSTDAASVVHSTDLVVEAI 108 >6BRD-A nrPDB Length = 476 Score = 37.6 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 19/33 (57%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA 56 +D +V+GGG G+ A +G + L++E + Sbjct: 2 FDVIVVGGGPTGLMLAGELRLHGVRVLVLEKET 34 Score = 30.6 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 16/35 (45%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLR 234 V+VVG G G+ LAG G ++ + R Sbjct: 4 VIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTR 38 >4A6N-B nrPDB Length = 398 Score = 37.6 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIR-GETVLRKFDECI---QNTITDHYVKEGI 253 K V ++G G +G+ +A + G + + R + R F + + + + K G+ Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGTLDLHKGSGQEAMKKAGL 86 Score = 33.7 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 34/180 (18%), Positives = 63/180 (35%), Gaps = 15/180 (8%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKA------LGGTC-VNVGCVPKKVMWYASDL 78 +IGGG G+ A+ G + E GGT ++ G ++ M A L Sbjct: 29 VAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGTLDLHKGS-GQEAMKKAGLL 87 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHR--LNGIYQKNLEKEKVDVVF 136 T A G+ T N + + ++R L I +LE + V Sbjct: 88 QTYYDLALPMGVNIADEKGNILSTKNVKPENRFDNPEINRNDLRAILLNSLENDTVIWDR 147 Query: 137 GWARFN-KDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEE 195 + + +E +A+ +++A GG + + + E + G F ++ Sbjct: 148 KLVMLEPGKKKWTLTFENKPSE--TADLVILANGGMSKVRKFVTDTE--VEETGTFNIQA 203 >3GG2-A nrPDB Length = 450 Score = 37.6 bits (86), Expect = 0.013, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 38/98 (38%), Gaps = 12/98 (12%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 + VVG GY+G+ A F LG+ R D + I +++ Sbjct: 5 IAVVGIGYVGLVSATCFAELGANV----------RCIDTDRNKI--EQLNSGTIPIYEPG 52 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS 297 + +NV+ +L+ +++ + D + +G + Sbjct: 53 LEKMIARNVKAGRLRFGTEIEQAVPEADIIFIAVGTPA 90 >4C3X-A nrPDB Length = 530 Score = 37.6 bits (86), Expect = 0.014, Method: Composition-based stats. Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 1/50 (2%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA-KALGGTCVNVG 65 M T D LV+G G G + A AA+ G T+++E GGT G Sbjct: 21 MQDWTSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTSAYSG 70 >6HRD-A nrPDB Length = 317 Score = 37.2 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 35/96 (36%), Gaps = 9/96 (9%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 ++V VVGAG +G +A V G E + E ++ I ++ Sbjct: 26 QRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERA--------VS 77 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTI 293 K+ + E++ L D + D +I + Sbjct: 78 AGKVTERERDRALGLLTFT-TDLNDLSDRQLVIEAV 112 >2YFH-A nrPDB Length = 448 Score = 37.2 bits (85), Expect = 0.017, Method: Composition-based stats. Identities = 34/201 (16%), Positives = 68/201 (33%), Gaps = 17/201 (8%) Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRL----NGIYQKNLEKEKVDVV 135 + A E+G D + F +++ A + + +G ++ + + Sbjct: 245 YAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKASRDGRVADYAKEFGLVYL 304 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-----FPENIPGFELGTDSDGF 190 G ++ ++ + A H L+A G KA+ P I EL + Sbjct: 305 EGQQPWSLPVDIALPCATQNELDVDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVL 364 Query: 191 FRLEEQPKKVVVVGAGYI-GIELAGVFHGLGSET-HLVIRGETVLRKFDECIQNTITDHY 248 F P K G G+E+A LG + + R ++ + + Sbjct: 365 FA----PGKAANAGGVATSGLEMAQNAARLGWKAEKVDARLHHIMTDIHDGSAAAAERYG 420 Query: 249 VKEGINVHKLSKIVKVEKNVE 269 + G N+ + IV +K + Sbjct: 421 L--GYNLVAGANIVGFQKIAD 439 >3IHG-A nrPDB Length = 535 Score = 37.2 bits (85), Expect = 0.018, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 N D LV+G G GG+++A A G + L+VE + Sbjct: 1 MNDHEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 Score = 33.3 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 15/35 (42%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLR 234 V+VVGAG G+ A G +V R + Sbjct: 8 VLVVGAGLGGLSTAMFLARQGVRVLVVERRPGLSP 42 >3WE0-A nrPDB Length = 580 Score = 36.8 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKALGG 59 + ++G G G+ +A G K ++ EA +GG Sbjct: 67 EVAIVGAGIAGLVAAYELMKLGLKPVVYEASKMGG 101 >2VVL-G nrPDB Length = 495 Score = 36.8 bits (84), Expect = 0.024, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 +D +VIGGG G+ + R G KTLL+E +GG Sbjct: 40 WDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGG 76 Score = 33.7 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 21/61 (34%), Gaps = 8/61 (13%) Query: 180 GFELGTDSDGFFRLEEQ--------PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 G G S G P V+V+G GY G+ G +T L+ + Sbjct: 14 GLTQGVTSLGVISPPTNIEDTDKDGPWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDR 73 Query: 232 V 232 + Sbjct: 74 I 74 >3HWR-A nrPDB Length = 318 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 35/95 (36%), Gaps = 21/95 (22%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 KV ++GAG +G G+ G E L+ R + V G+ + Sbjct: 21 KVAIMGAGAVGCYYGGMLARAGHEVILIARPQHV-------------QAIEATGLRLETQ 67 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTI 293 S +V+ + +D ++ D +++ + Sbjct: 68 SFDEQVKVSA--------SSDPSAVQGADLVLFCV 94 >1KNR-A nrPDB Length = 540 Score = 36.4 bits (83), Expect = 0.027, Method: Composition-based stats. Identities = 6/22 (27%), Positives = 15/22 (68%) Query: 314 DQIIADEYQNTNVPNIYSLGDV 335 ++ D++ T+V +Y++G+V Sbjct: 355 GGVMVDDHGRTDVEGLYAIGEV 376 Score = 31.8 bits (71), Expect = 0.72, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 17 MSTNTKHY-DYLVIGGGSGGVASARRAASYGAKTLL 51 M+T +H D L+IG G+ G++ A R A +L Sbjct: 1 MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVL 36 >6ACQ-A nrPDB Length = 302 Score = 36.0 bits (82), Expect = 0.036, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 9/95 (9%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 KKV V+GAG +G +A F G E VLR + + D K + K Sbjct: 22 KKVCVIGAGTMGSGIAQAFAAKGFEV--------VLRDIKDEFVDRGLDFINKNLSKLVK 73 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWT 292 KI + K ++ + D D D +I Sbjct: 74 KGKIEEATKVEILTRISGTV-DLNMAADCDLVIEA 107 >4MO2-B nrPDB Length = 368 Score = 35.6 bits (81), Expect = 0.050, Method: Composition-based stats. Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTC 61 YDYL++G G G A A G L+VE + +GG C Sbjct: 2 YDYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNC 40 >2GAG-B nrPDB Length = 405 Score = 35.6 bits (81), Expect = 0.050, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 2/40 (5%) Query: 22 KHYDYLVIGGGSGGVA-SARRAASYGA-KTLLVEAKALGG 59 K YD +++GGG G+A + A ++G ++E L G Sbjct: 20 KSYDAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAG 59 >1SEZ-A nrPDB Length = 504 Score = 35.6 bits (81), Expect = 0.050, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAKALGG 59 VIG G G+A+A + +G + EA+ G Sbjct: 16 VAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAG 49 Score = 34.9 bits (79), Expect = 0.087, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 13/31 (41%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIR 228 K+V V+GAG G+ A G + Sbjct: 14 KRVAVIGAGVSGLAAAYKLKIHGLNVTVFEA 44 >4MOP-A nrPDB Length = 633 Score = 35.6 bits (81), Expect = 0.053, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 15/35 (42%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKAL 57 YD +++G G G AR G K + + + Sbjct: 46 KYDVVIVGSGPIGCTYARELVGAGYKVAMFDIGEI 80 Score = 29.1 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 16/32 (50%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 VV+VG+G IG A G G + + GE Sbjct: 49 VVIVGSGPIGCTYARELVGAGYKVAMFDIGEI 80 >4DGK-A nrPDB Length = 501 Score = 35.2 bits (80), Expect = 0.061, Method: Composition-based stats. Identities = 15/33 (45%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 28 VIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 VIG G GG+A A R + G LL+E GG Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGG 38 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 16/35 (45%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 K V+GAG+ G+ LA G L+ + + Sbjct: 2 KPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKP 36 >4YNU-A nrPDB Length = 571 Score = 35.2 bits (80), Expect = 0.063, Method: Composition-based stats. Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASY-GAKTLLVEAKA 56 NT YDY+V+GGG+ G+ A R + LL+EA A Sbjct: 1 MNTTTYDYIVVGGGTSGLVVANRLSENPDVSVLLLEAGA 39 >5L46-A nrPDB Length = 841 Score = 35.2 bits (80), Expect = 0.068, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 41/101 (40%), Gaps = 25/101 (24%) Query: 27 LVIGGGSGGVASARRAASYGAK-TLLVEAKAL--GGTCVNVGCVPKKVMWYASDLATRVS 83 ++IGGG GV+ A A G K +L+E L G T W+A+ L T Sbjct: 26 VIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGST------------WHAAGLTTYFH 73 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ 124 ++ + + ++ + +K + ++ G +Q Sbjct: 74 ----------PGINLKKIHYDSIKLYEKLEEETGQVVGFHQ 104 Score = 29.1 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 200 VVVVGAGYIGIELAGVFHGLG-SETHLVIRGE 230 V++G G +G+ LA G + L+ + E Sbjct: 25 TVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSE 56 >5EB4-A nrPDB Length = 532 Score = 34.9 bits (79), Expect = 0.076, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 4/60 (6%) Query: 1 MLSATKQTFRSLQIRTMSTNTKH---YDYLVIGGGSGGVASARRAASYGAKTLLVEAKAL 57 + + + F L+ +T+T YDY+VIGGG+ G A + K LL+E + Sbjct: 1 LANTSAHDFSYLKFVYNATDTSSEGSYDYIVIGGGTSGCPLAATLSE-KYKVLLLERGTI 59 >3KYB-A nrPDB Length = 390 Score = 34.9 bits (79), Expect = 0.077, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 20/35 (57%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 KK+++VGAG+ G + G + H++ + + + Sbjct: 4 KKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHI 38 >6H3G-A nrPDB Length = 651 Score = 34.9 bits (79), Expect = 0.082, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 20 NTKHYDYLVIGGGSGG-VASARRA-ASYGAKTLLVEAKA 56 + + D +V GGG G V + R A A K +L+E A Sbjct: 3 HPEEVDVIVCGGGPAGCVVAGRLAYADPTLKVMLIEGGA 41 >5XGV-A nrPDB Length = 462 Score = 34.9 bits (79), Expect = 0.082, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL-RKFDECIQNTITDHYVKEGI 253 V++ G G +G+ LA G +T ++ R + I T+ + + + GI Sbjct: 2 DTVIIAGGGPVGLMLACELGLAGVDTVVLERHDAPREPSRGGAINATVVELFTQRGI 58 >3Q9T-A nrPDB Length = 577 Score = 34.9 bits (79), Expect = 0.090, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 24/41 (58%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALG 58 +T+ H+D++++GGG+ G A R A T+L+ +G Sbjct: 1 ATDGSHFDFVIVGGGTAGNTVAGRLAENPNVTVLIVEAGIG 41 >3UKH-A nrPDB Length = 519 Score = 34.9 bits (79), Expect = 0.090, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 25 DYLVIGGGSGGVASARRAASY-GAKTLLVEAKAL-GG 59 D LVIG G G+ +A+R G ++V++ GG Sbjct: 8 DVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGG 44 >5EZ7-A nrPDB Length = 392 Score = 34.5 bits (78), Expect = 0.097, Method: Composition-based stats. Identities = 15/37 (40%), Positives = 21/37 (56%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGG 59 D L++GGG G+ R G T+LVE+ +LGG Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGYATVLVESASLGG 43 Score = 28.3 bits (62), Expect = 8.0, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 13/31 (41%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGE 230 +++VG G G+ L G T LV Sbjct: 10 ILIVGGGIAGLWLNARLRRAGYATVLVESAS 40 >4FHN-X nrPDB Length = 450 Score = 34.5 bits (78), Expect = 0.097, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 50/151 (33%), Gaps = 14/151 (9%) Query: 80 TRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYV----HRLNGIYQKNLEKEKVDVV 135 + A E+G D + F +++ A + +G ++ + + Sbjct: 249 YAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKSSRDGRVADYAKEFGLVYL 308 Query: 136 FGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAI-----FPENIPGFELGTDSDGF 190 G ++ ++ + A H L+A G KA+ P I EL + Sbjct: 309 EGQQPWSVPVDIALPCATQNELDVDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVL 368 Query: 191 FRLEEQPKKVVVVGAGYI-GIELAGVFHGLG 220 F P K G G+E+A LG Sbjct: 369 FA----PGKAANAGGVATSGLEMAQNAARLG 395 >4P9S-A nrPDB Length = 848 Score = 34.5 bits (78), Expect = 0.11, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 41/101 (40%), Gaps = 25/101 (24%) Query: 27 LVIGGGSGGVASARRAASYGAK-TLLVEAKAL--GGTCVNVGCVPKKVMWYASDLATRVS 83 ++IGGG GV+ A A G + +L+E L G T W+A+ L T Sbjct: 27 VIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGST------------WHAAGLTTYFH 74 Query: 84 HANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ 124 ++ + + ++ + ++ + ++ G +Q Sbjct: 75 ----------PGINLKKIHYDSIKLYERLEEETGQVVGFHQ 105 Score = 29.1 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 200 VVVVGAGYIGIELAGVFHGLGS-ETHLVIRGE 230 V++G G +G+ LA G + L+ + E Sbjct: 26 TVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSE 57 >6DLL-A nrPDB Length = 398 Score = 34.5 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 54/142 (38%), Gaps = 25/142 (17%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG-INVHKL 258 V ++GAG G+ L + H G + +V R E + I +++G +++ + Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIVERQTA------EYVLGRIRAGVLEQGTVDLLRE 61 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQIIA 318 + + E+ + + EL+ GR+ L + + G + + Q Sbjct: 62 AGVA--ERMDREGLVH----------EGVELLVG-GRRQRLDLKALTGGKTVMVYGQTEV 108 Query: 319 D-----EYQNTNVPNIYSLGDV 335 + + P IYS +V Sbjct: 109 TRDLMQAREASGAPIIYSAANV 130 >2E5V-A nrPDB Length = 472 Score = 34.1 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 53/172 (30%), Gaps = 30/172 (17%) Query: 28 VIGGGSGGVASARRAASYGAKTLLVEAK--------ALGGTCVNVG-------------- 65 +IG G G+++ G K L+ + A GG +VG Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLISKRIDGGSTPIAKGGVAASVGSDDSPELHAQDTIR 63 Query: 66 -----CVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLN 120 C K V + S+ + +G L E + D + Sbjct: 64 VGDGLCDVKTVNYVTSEAKNVIETFESWGFEFEEDLRLEGG-HTKRRVLHRTDETGREIF 122 Query: 121 GIYQKNLEKEKVDVVFGW--ARFNKDGNVEVQKRDNTTEVYSANHILVATGG 170 K +E + ++ KDG V + V + +++ATGG Sbjct: 123 NFLLKLAREEGIPIIEDRLVEIRVKDGKVTGFVTEKRGLVEDVDKLVLATGG 174 Score = 29.9 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 5/25 (20%), Positives = 11/25 (44%) Query: 202 VVGAGYIGIELAGVFHGLGSETHLV 226 ++G+G G+ G + L+ Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLI 28 >3CP8-A nrPDB Length = 641 Score = 34.1 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLV 52 + YD +V+G G G +A A G LL+ Sbjct: 18 GSHMYDVIVVGAGHAGCEAALAVARGGLHCLLI 50 >4K2X-A nrPDB Length = 523 Score = 34.1 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 17/31 (54%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 YD ++ G G G+ A GA+TL++E Sbjct: 23 YDVVIAGAGPTGLMLACELRLAGARTLVLER 53 Score = 29.5 bits (65), Expect = 3.8, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETV 232 VV+ GAG G+ LA G+ T ++ R Sbjct: 25 VVIAGAGPTGLMLACELRLAGARTLVLERLAEP 57 >1X14-A nrPDB Length = 401 Score = 34.1 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 22/56 (39%) Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 P KV+V+GAG G+ G + LG+ V + + + +E Sbjct: 171 PPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEE 226 Score = 28.3 bits (62), Expect = 8.4, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 15/30 (50%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVEAK 55 +VIG G G+A+ A S GA + + Sbjct: 175 VMVIGAGVAGLAAIGAANSLGAIVRAFDTR 204 >4H7U-A nrPDB Length = 602 Score = 34.1 bits (77), Expect = 0.16, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 20/34 (58%), Gaps = 1/34 (2%) Query: 23 HYDYLVIGGGSGGVASARRAAS-YGAKTLLVEAK 55 YD++V GGG+ G+ A R + K L++EA Sbjct: 40 DYDFIVAGGGTAGLVVASRLSENSNWKVLVIEAG 73 >5I68-A nrPDB Length = 663 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 2/38 (5%) Query: 21 TKHYDYLVIGGGSGGVASARRAA--SYGAKTLLVEAKA 56 + +D LV+GGGS G A R A + K L+EA Sbjct: 4 PEEFDILVLGGGSSGSCIAGRLANLDHSLKVGLIEAGE 41 >3S61-A nrPDB Length = 463 Score = 33.7 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 35/254 (13%), Positives = 79/254 (31%), Gaps = 69/254 (27%) Query: 146 NVEVQKRDNTTEVYSANHILVATGGKAIFP---ENIPGFELGTDSDGFFRLEEQ------ 196 V + D V + ++V+ GG P + G + + Sbjct: 166 RVISRNADGEELVRTTRALVVSPGGTPRIPQVFRALKGDGRVFHHSQYLEHMAKQPCSSG 225 Query: 197 -PKKVVVVGAGYIGIE----LAGVFHGLGSE-------------------------THLV 226 P K+ ++G G E L + + ++ T L+ Sbjct: 226 KPMKIAIIGGGQSAAEAFIDLNDSYPSVQADMILRASALKPADDSPFVNEVFAPKFTDLI 285 Query: 227 IR-----GETVLRKF--------DECIQNTITDHYVKEGIN------VHKLSKIVKVEKN 267 E +LR++ D + I + ++ ++ ++ + + Sbjct: 286 YSREHAERERLLREYHNTNYSVVDTDLIERIYGVFYRQKVSGIPRHAFRCMTTVERATAT 345 Query: 268 VETDKLKIHMNDSKS--IDDVDELIWTIG--RKSHLGM---GSENVG-IKLNSHDQIIAD 319 + +L + S ++ D +I G R+ H + +E +G ++ ++ D Sbjct: 346 AQGIELALRDAGSGELSVETYDAVILATGYERQLHRQLLEPLAEYLGDHEIGRDYRLQTD 405 Query: 320 EYQNTNVPNIYSLG 333 E IY+ G Sbjct: 406 ERCKVA---IYAQG 416 >2Y0D-A nrPDB Length = 478 Score = 33.7 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 37/285 (12%), Positives = 90/285 (31%), Gaps = 45/285 (15%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 + ++G+G +G+ +G + F + D G+ +H+ Sbjct: 11 LTIIGSGKVGLVTGACLADIGHDV------------FCLDVDQAKIDILNNGGVPIHEPG 58 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG---------MGSENVGIKL 310 + +N +L+ + ++ D +G + N+G + Sbjct: 59 LKEVIARNRSAGRLRFSTDIEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRYM 118 Query: 311 NSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYE 370 ++I D + VP +G + VA ++ +++F N + E Sbjct: 119 TGF-KVIVD---KSTVP----VG--TAERVRAAVAEELAKRGGDQMF--SVVSNPEFLKE 166 Query: 371 NVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAM-YYAMLSE-KSPTRYKIVC 428 F+ P+ IG + + + +E +K + F + + +S K Sbjct: 167 GAAVDDFTRPDRIVIG-CDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAA 225 Query: 429 AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHP 473 ++ + + + +A + GA + P Sbjct: 226 NA---------MLATRISFMNELANLADRFGADIEAVRRGIGSDP 261 >4RPJ-A nrPDB Length = 399 Score = 33.7 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARR-AASYGAKTLLVEAK-ALGGT 60 M T +D V+G G G+ A R A + L++E + +GG Sbjct: 1 MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGN 46 >3COX-A nrPDB Length = 507 Score = 33.7 bits (76), Expect = 0.19, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 15/30 (50%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEAKA 56 LVIG G GG +A R G T +VE Sbjct: 15 LVIGSGYGGAVAALRLTQAGIPTQIVEMGR 44 >4B4O-A nrPDB Length = 298 Score = 33.7 bits (76), Expect = 0.20, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 23/48 (47%), Gaps = 2/48 (4%) Query: 199 KVVVVGA-GYIGIELAGVFHGLGSETHLVIRGETVLR-KFDECIQNTI 244 +V+V G G+IG L + + G E LV R R +DE + + Sbjct: 2 RVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGL 49 >5MOG-A nrPDB Length = 497 Score = 33.3 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 1/41 (2%) Query: 20 NTKHYDYLVIGGGSGGVASARRAASYGAKTLLVE-AKALGG 59 TK ++ G G G+++A+ A G K +L+E LGG Sbjct: 14 PTKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGG 54 >3HN2-A nrPDB Length = 312 Score = 33.3 bits (75), Expect = 0.22, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 18/32 (56%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGE 230 ++ +VGAG +G+ + G + H ++R + Sbjct: 4 RIAIVGAGALGLYYGALLQRSGEDVHFLLRRD 35 >4IIN-A nrPDB Length = 271 Score = 33.3 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 29/85 (34%), Gaps = 8/85 (9%) Query: 198 KKVVVVGAGY-IGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVH 256 K V++ GA IG E+A +G + + R + + + + ++G Sbjct: 30 KNVLITGASKGIGAEIAKTLASMGLKVWINYRSN-------AEVADALKNELEEKGYKAA 82 Query: 257 KLSKIVKVEKNVETDKLKIHMNDSK 281 + E + I +D Sbjct: 83 VIKFDAASESDFIEAIQTIVQSDGG 107 >1FOH-A nrPDB Length = 664 Score = 33.3 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 22/42 (52%), Gaps = 6/42 (14%) Query: 21 TKHY-DYLVIGGGSGGVASARRAASY-----GAKTLLVEAKA 56 ++ Y D L++G G G+ +AR + Y K +++ ++ Sbjct: 4 SESYCDVLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKRS 45 >5KOX-A nrPDB Length = 476 Score = 33.3 bits (75), Expect = 0.24, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 17/30 (56%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEA 54 D ++ GGG G+ A +G +T+++E Sbjct: 6 DVIIAGGGPTGLMLAGELRLHGVRTVVLEK 35 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 27/87 (31%), Gaps = 10/87 (11%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETV----------LRKFDECIQNTITDHYV 249 V++ G G G+ LAG G T ++ + T R + Q + + ++ Sbjct: 7 VIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHSRSRGLHARSIEVMDQRGLLERFL 66 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIH 276 G + D H Sbjct: 67 AHGEQFRVGGFFAGLAAEWPADLDTAH 93 >3G5Q-A nrPDB Length = 443 Score = 32.9 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 14/34 (41%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 ++V VVGAG G E A LG L Sbjct: 2 ERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPK 35 >1DOD-A nrPDB Length = 394 Score = 32.9 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRG 229 V ++GAG G+ L + H G + ++ R Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVILERQ 34 >4XRR-A nrPDB Length = 456 Score = 32.9 bits (74), Expect = 0.30, Method: Composition-based stats. Identities = 16/37 (43%), Positives = 19/37 (51%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGE 230 E P KVV+ GAGY+G LA G G+E V Sbjct: 12 EPSPLKVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDP 48 >5PGZ-A nrPDB Length = 276 Score = 32.9 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 198 KKVVVVGAGY-IGIELAGVFHGLGSETHLVIRGETVLRK 235 KKV+V GA IG E+A +G+ L R E L+K Sbjct: 19 KKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQK 57 >4N9X-A nrPDB Length = 411 Score = 32.6 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 19/36 (52%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA 56 + +D ++ GGG G+A A G + ++E +A Sbjct: 1 MQSFDVVIAGGGMVGLALACGLQGSGLRIAVLEKQA 36 >2XVH-A nrPDB Length = 464 Score = 32.6 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 34/93 (36%), Gaps = 15/93 (16%) Query: 142 NKDGNVEVQKRDNTTEVY---SANHILVATG--GKAIFPENIPGFE-------LGTDSDG 189 V +D+TT+ ++++ TG P GFE D Sbjct: 133 EDSQTFTVTVQDHTTDTIYSEEFDYVVCCTGHFSTPYVP-EFEGFEKFGGRILHAHDFRD 191 Query: 190 FFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSE 222 ++ K V++VG+ Y ++ + G++ Sbjct: 192 ALEFKD--KTVLLVGSSYSAEDIGSQCYKYGAK 222 >1E3J-A nrPDB Length = 352 Score = 32.6 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 14/28 (50%) Query: 24 YDYLVIGGGSGGVASARRAASYGAKTLL 51 LVIG G G+ S A +YGA + Sbjct: 170 TTVLVIGAGPIGLVSVLAAKAYGAFVVC 197 >3WSV-A nrPDB Length = 322 Score = 32.6 bits (73), Expect = 0.43, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 47/142 (33%), Gaps = 26/142 (18%) Query: 194 EEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGI 253 ++ +KVV+VG G++G +A G + E VL ++ EG Sbjct: 2 KKTSRKVVIVGTGFVGTSIAYAMINQG------VANELVLIDVNQE---------KAEGE 46 Query: 254 NVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGR---KSHLGMGSENVGIKL 310 + L + EKN + + + D + +I T G + + Sbjct: 47 ALDLLDGMAWGEKN-----VSVWSGTYEECQDANLVILTAGVNQKPGQTRLDLVKTNATI 101 Query: 311 NSHDQIIADEYQNTNVPNIYSL 332 I E + I+ + Sbjct: 102 TRQ---IVKEVMASGFDGIFVV 120 >4KUG-A nrPDB Length = 290 Score = 32.6 bits (73), Expect = 0.44, Method: Composition-based stats. Identities = 25/95 (26%), Positives = 36/95 (37%), Gaps = 9/95 (9%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 KKV V+GAG +G + F G E + E D I TIT K + Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEF---VDRGIA-TITKSLSK----LVA 53 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWT 292 KI + +K ++ D K D D ++ Sbjct: 54 KEKITEADKEEILSRISGT-TDMKLAADCDLVVEA 87 >4CPD-A nrPDB Length = 347 Score = 32.2 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 37/107 (34%), Gaps = 21/107 (19%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 V V+GAG +G+ + E V+ +L + I + + Sbjct: 170 DSVAVIGAGPVGL--------MAIEVAQVLGASKIL------AIDRIPERLERAA---SL 212 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSE 304 + + E+ +++ ND D ++ +G + L + E Sbjct: 213 GAIPINAEQENPVRRVRSETNDEGP----DLVLEAVGGAATLSLALE 255 >1GPE-A nrPDB Length = 587 Score = 32.2 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 22 KHYDYLVIGGGSGGVASARRAASY-GAKTLLVEAKAL 57 K YDY++ GGG G+ A + K L++E Sbjct: 23 KTYDYIIAGGGLTGLTVAAKLTENPKIKVLVIEKGFY 59 >4UDQ-A nrPDB Length = 531 Score = 32.2 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Query: 24 YDYLVIGGGSGGVASARR-AASYGAKTLLVEAK 55 +DY+++GGG+ G A R +A + LL+EA Sbjct: 6 FDYVIVGGGTAGSVLANRLSARPENRVLLIEAG 38 >4U2L-A nrPDB Length = 510 Score = 32.2 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEAKAL 57 +VIG G G SA R G +TL++E L Sbjct: 9 VVIGTGYGAAVSALRLGEAGVQTLMLEMGQL 39 >4L68-A nrPDB Length = 340 Score = 32.2 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 24/71 (33%), Gaps = 9/71 (12%) Query: 202 VVGAGYIGIELAGVFHGLGSE---------THLVIRGETVLRKFDECIQNTITDHYVKEG 252 V G G + +ELA +G E + + FDE I+ D + + Sbjct: 226 VYGLGVVLLELATGLKAVGGEGFKGSLVDWVKQLESSGRIAETFDENIRGKGHDEEISKF 285 Query: 253 INVHKLSKIVK 263 + + + Sbjct: 286 VEIALNCVSSR 296 >6J0Z-C nrPDB Length = 491 Score = 32.2 bits (72), Expect = 0.56, Method: Composition-based stats. Identities = 23/184 (12%), Positives = 54/184 (29%), Gaps = 33/184 (17%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVP---KKVMWYA 75 D +V+G G G+ A G ++++ A P + + ++ Sbjct: 1 MEFYDSDVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAE----------PIKESRALGFS 50 Query: 76 SDLATRVSHAN-----------EYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQ 124 + + G + +PLD + + + A + G + Sbjct: 51 ARTIEEFAQRGLMDRFGEVGVIPVGHFGGVPLDYQVIEGGSYGARGIPQARTEGILGGWA 110 Query: 125 KNL-----EKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIP 179 + L +V + VE D + A +++ G ++ + Sbjct: 111 RELGAEVRRGYEVTAIEDTGTSV---TVEAAGADGSPLSLRARYVVGCDGARSSV-RKLA 166 Query: 180 GFEL 183 G + Sbjct: 167 GIDF 170 Score = 31.8 bits (71), Expect = 0.68, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 10/64 (15%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVL----------RKFDECIQNTITDHYV 249 VVVVGAG G+ LAG G ++ + + R +E Q + D + Sbjct: 8 VVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEPIKESRALGFSARTIEEFAQRGLMDRFG 67 Query: 250 KEGI 253 + G+ Sbjct: 68 EVGV 71 >5NCC-A nrPDB Length = 594 Score = 32.2 bits (72), Expect = 0.57, Method: Composition-based stats. Identities = 12/31 (38%), Positives = 21/31 (67%) Query: 22 KHYDYLVIGGGSGGVASARRAASYGAKTLLV 52 + YDY+++GGG+ A R ++ G+K +LV Sbjct: 22 QKYDYILVGGGTAACVLANRLSADGSKRVLV 52 >3BI4-A nrPDB Length = 516 Score = 32.2 bits (72), Expect = 0.57, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 20/36 (55%), Gaps = 1/36 (2%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGS-ETHLVIRGETV 232 KKV+++GAG G++ A H G + ++ + V Sbjct: 9 KKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRV 44 >5XMJ-A nrPDB Length = 627 Score = 32.2 bits (72), Expect = 0.58, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 16/34 (47%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLV 52 H D L IGG G A A+ G KT+++ Sbjct: 1 MQIYHTDVLCIGGALAGERVAVEASMAGLKTIML 34 >2Y08-A nrPDB Length = 530 Score = 32.2 bits (72), Expect = 0.59, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 2/53 (3%) Query: 324 TNVPNIYSLGDVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 T P I GD+ G+ ++ A A R +R G R DY+N V+ Sbjct: 352 TRWPGIAGDGDMTGRAKI--KAAYARRSFDDRQIGTLYTRLTSTDYDNPAGVV 402 >1LQU-A nrPDB Length = 456 Score = 32.2 bits (72), Expect = 0.60, Method: Composition-based stats. Identities = 30/166 (18%), Positives = 59/166 (35%), Gaps = 30/166 (18%) Query: 140 RFNKDGNVEVQKRDNTTE-VYSANHILVATGGKAIFPENIPGFEL--GTDSDGF------ 190 RF GNV V + E + ++ A G ++ NIPG +L + F Sbjct: 75 RFRFFGNVVVGEHVQPGELSERYDAVIYAVGAQSDRMLNIPGEDLPGSIAAVDFVGWYNA 134 Query: 191 ------FRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 + + VV+G G + +++A + + ++ R + I + Sbjct: 135 HPHFEQVSPDLSGARAVVIGNGNVALDVARILLT---DPDVLARTD---------IADHA 182 Query: 245 TDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELI 290 + GI IV ++ + + + +D VD +I Sbjct: 183 LESLRPRGIQ---EVVIVGRRGPLQAAFTTLELRELADLDGVDVVI 225 >3LLV-A nrPDB Length = 141 Score = 31.8 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 18/36 (50%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEA 54 T Y+Y+VIG + GV R + G K L V+ Sbjct: 2 TENGRYEYIVIGSEAAGVGLVRELTAAGKKVLAVDK 37 >3GDN-A nrPDB Length = 521 Score = 31.8 bits (71), Expect = 0.64, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNV 64 YDY+++GGG+ G A + K L++E +L NV Sbjct: 26 SYDYVIVGGGTSGCPLAATLSE-KYKVLVLERGSLPTAYPNV 66 >5TUF-A nrPDB Length = 409 Score = 31.8 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 28/123 (22%), Positives = 46/123 (37%), Gaps = 20/123 (16%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKAL---GGTCVNVGCVPKKVMWYA 75 TKH LVIG G G A A +G +L+E A GG A Sbjct: 21 MMTKHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAAVRKGG--------------QA 66 Query: 76 SDLATRVSH-ANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDV 134 D+ +H A E G+Y + + + + + +H G + ++V++ Sbjct: 67 LDIRGIATHIAKEMGIYDQICNMRTQIKCG--RYVDVKGNVLHEEQGETFGFRQDDEVEI 124 Query: 135 VFG 137 + G Sbjct: 125 LRG 127 >3V8E-A nrPDB Length = 216 Score = 31.8 bits (71), Expect = 0.65, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 24/62 (38%), Gaps = 9/62 (14%) Query: 200 VVVVGAGYIGIEL-----AGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 V +VG + +E A LG +T +++ + D + N + + IN Sbjct: 157 VYIVG---VALEYCVKATAISAAELGYKTTVLLDYTRPISD-DPEVINKVKEELKAHNIN 212 Query: 255 VH 256 V Sbjct: 213 VV 214 >4IV9-A nrPDB Length = 557 Score = 31.8 bits (71), Expect = 0.74, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 21/66 (31%), Gaps = 6/66 (9%) Query: 199 KVVVVGAGYIGIELAGVFHGLGS-ETHLVIRGETVLRK-----FDECIQNTITDHYVKEG 252 +V +VGAG G+ A G + L + + + FD+ I + Sbjct: 40 RVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRF 99 Query: 253 INVHKL 258 Sbjct: 100 PPSATG 105 >3P7M-A nrPDB Length = 321 Score = 31.8 bits (71), Expect = 0.78, Method: Composition-based stats. Identities = 31/135 (22%), Positives = 54/135 (40%), Gaps = 21/135 (15%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 KK+ +VGAG IG G L + G+ VL + + N + +++ + Sbjct: 6 KKITLVGAGNIG----GTLAHLAL---IKQLGDVVLFDIAQGMPNG-------KALDLLQ 51 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII 317 I V+ V ND K +++ D +I T G GM +++ + +N Sbjct: 52 TCPIEGVDFKVRGT------NDYKDLENSDVVIVTAGVPRKPGMSRDDL-LGINIKVMQT 104 Query: 318 ADEYQNTNVPNIYSL 332 E N PN + + Sbjct: 105 VGEGIKHNCPNAFVI 119 >1RP0-A nrPDB Length = 284 Score = 31.4 bits (70), Expect = 0.79, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Query: 23 HYDYLVIGGGSGGVASARRAASY-GAKTLLVE 53 D +V+G GS G+++A + + ++E Sbjct: 39 ETDVVVVGAGSAGLSAAYEISKNPNVQVAIIE 70 >3RED-A nrPDB Length = 521 Score = 31.4 bits (70), Expect = 0.82, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKAL 57 YDY+++GGG+ G A + K L++E L Sbjct: 26 SYDYVIVGGGTSGCPLAATLSE-KYKVLVLERGTL 59 >3IHM-A nrPDB Length = 430 Score = 31.4 bits (70), Expect = 0.85, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 13/28 (46%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHL 225 K++ +VGAG G+ L + + Sbjct: 23 KRIGIVGAGTAGLHLGLFLRQHDVDVTV 50 >5WIT-1k nrPDB Length = 129 Score = 31.4 bits (70), Expect = 0.85, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 7/59 (11%) Query: 20 NTKHYDYLVIGGGSGGVASARRAAS-YGAKT-LLVEAKALGGTCVNVGCVPKKVMWYAS 76 + D +V G G G A RA G + +V+ + + GC PKK AS Sbjct: 76 GMQSVDVIVRGTG-AGREQAIRALQASGLQVKSIVDDTPV----PHNGCRPKKKFRKAS 129 >2CDC-A nrPDB Length = 366 Score = 31.4 bits (70), Expect = 0.93, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 18/33 (54%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGE 230 +KV+VVG G IG+ +F G E + R E Sbjct: 182 RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRRE 214 >2GAG-A nrPDB Length = 965 Score = 31.4 bits (70), Expect = 0.97, Method: Composition-based stats. Identities = 50/300 (16%), Positives = 91/300 (30%), Gaps = 49/300 (16%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA-LGGTCVNVGCVPKKVMWYASDLATR 81 H D LV+G G G+A+AR A+ GA+ +L++ +A GGT ++ M ++ + Sbjct: 128 HTDVLVVGAGPAGLAAAREASRSGARVMLLDERAEAGGTLLDTAGEQIDGMDSSAWIEQV 187 Query: 82 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 S E +L +++ + VH V W Sbjct: 188 TSELAEAEETTHLQRTTVFGSYDANYLIAAQRRTVHL------DGPSGPGVSRERIW--- 238 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGG--KAIF--PENIPGFELGTDSDGFFRL--EE 195 A +++ATG + I + PG L + Sbjct: 239 ----------------HIRAKQVVLATGAHERPIVFENNDRPGIMLAGAVRSYLNRYGVR 282 Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINV 255 ++ V EL G ++ + + V +G+ V Sbjct: 283 AGARIAVATTNDSAYELVRELAATGGVVAVIDARSS---------ISAAAAQAVADGVQV 333 Query: 256 HKLSKIVKVEKNVETDKLKIHMN--------DSKSIDDVDELIWTIGRKSHLGMGSENVG 307 S +V E + + I + + D L G + + S+ G Sbjct: 334 ISGSVVVDTEADENGELSAIVVAELDEARELGGTQRFEADVLAVAGGFNPVVHLHSQRQG 393 >4NEG-A nrPDB Length = 400 Score = 31.4 bits (70), Expect = 0.98, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 31/74 (41%), Gaps = 4/74 (5%) Query: 389 EKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEI 448 E EA +K +K Y + T +Y+A + KI + G H + ++ Sbjct: 43 EDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNT---- 98 Query: 449 LQGFGVAIKMGATK 462 + +A++MG K Sbjct: 99 IGQALLAVRMGKKK 112 >3RIM-A nrPDB Length = 700 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 28/83 (33%), Gaps = 6/83 (7%) Query: 90 LYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGW-ARFNKDGNVE 148 L P D + W +R+ +G L ++ V V+ G A G Sbjct: 518 LSVVRPADANETAYAWRTILARRNG-----SGPVGLILTRQGVPVLDGTDAEGVARGGYV 572 Query: 149 VQKRDNTTEVYSANHILVATGGK 171 + + IL+ATG + Sbjct: 573 LSDAGGLQPGEEPDVILIATGSE 595 >3G05-A nrPDB Length = 576 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 40/117 (34%), Gaps = 11/117 (9%) Query: 18 STNTKHYDYLVIGGGSGGVASARRAASYGAKTLLV--EAKALGGTCVNVGCVPKKVMWYA 75 S +D ++IGGG G +A AA G +TLL+ LG + C P Sbjct: 27 SFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLG----QMSCNPA---IGG 79 Query: 76 SDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 V + G +D+ + F + V + L ++ V Sbjct: 80 IGKGHLVKEVDALGGLMAKAIDQAGIQF--RILNASKGPAVRATRAQADRVLYRQAV 134 >2EEZ-A nrPDB Length = 369 Score = 31.0 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 197 PKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD 237 P VV++G G +G A + G+G++ ++ L+ D Sbjct: 166 PASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLD 206 Score = 27.9 bits (61), Expect = 9.9, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 18/28 (64%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVE 53 +++GGG+ G +A+ A GA+ +++ Sbjct: 169 VVILGGGTVGTNAAKIALGMGAQVTILD 196 >4R16-A nrPDB Length = 418 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 24/53 (45%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 ++ V+G GYIG+ A +F G + V++K + + + I + Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRR 54 >3F3S-A nrPDB Length = 313 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 VV+VG+G IG A +F G + L + +R E I+ + Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEM 50 >3CP2-A nrPDB Length = 649 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 39/114 (34%), Gaps = 11/114 (9%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLV--EAKALGGTCVNVGCVPKKVMWYASDL 78 +D ++IGGG G +A AA G +TLL+ LG + C P Sbjct: 24 PDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLG----QMSCNPA---IGGIGK 76 Query: 79 ATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKV 132 V + G +D+ + F + V + L ++ V Sbjct: 77 GHLVKEVDALGGLMAKAIDQAGIQF--RILNASKGPAVRATRAQADRVLYRQAV 128 >3DWF-A nrPDB Length = 276 Score = 31.0 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 1/39 (2%) Query: 198 KKVVVVGAGY-IGIELAGVFHGLGSETHLVIRGETVLRK 235 KKV+V GA IG E+A +G+ + R + L+K Sbjct: 12 KKVIVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQK 50 >3OJO-A nrPDB Length = 431 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 21/102 (20%), Positives = 38/102 (37%), Gaps = 16/102 (15%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKL 258 K+ VVG GYIG+ + +F G + V I D I++ + Sbjct: 13 KLTVVGLGYIGLPTSIMFAKHGVDVLGV------------DINQQTIDKLQNGQISIEEP 60 Query: 259 SKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 E+ + + KLK+ S + + D I + ++ Sbjct: 61 GLQEVYEEVLSSGKLKV----STTPEASDVFIIAVPTPNNDD 98 >2IVE-A nrPDB Length = 478 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%), Gaps = 3/63 (4%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V VVG G G+ +A G++ L+ + + + + V++G N Sbjct: 19 VAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVG---THALAGYLVEQGPNSFLDR 75 Query: 260 KIV 262 + Sbjct: 76 EPA 78 >4V8P-BH nrPDB Length = 215 Score = 30.6 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 36/91 (39%), Gaps = 10/91 (10%) Query: 353 SNRLFGPEKFRNDKLDYENVPSVIFS------HPEAGSIGISEKEAIEKYGKENIKVYNS 406 FG + ++D + S++FS H + ++ +A ++ + Sbjct: 115 MRGAFGKALGKAARVD---IGSILFSVRVKEPHVKYAIDALTRAKAKFPGRQKVVTSQKW 171 Query: 407 KFTAMYYAMLSEKSPTRYKIVCAGPNEKVVG 437 FT + A S + K+V G N KV+G Sbjct: 172 GFTKLTRAQYSRLRNQK-KLVTDGSNVKVIG 201 >3OZ2-A nrPDB Length = 397 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 7/66 (10%) Query: 38 SARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASD-------LATRVSHANEYGL 90 +AR AA YG KTL++E + G+ V G K + +D +A V A YG Sbjct: 19 AARYAAKYGLKTLMIEKRPEIGSPVRCGEGLSKGILNEADIKADRSFIANEVKGARIYGP 78 Query: 91 YQNLPL 96 + P+ Sbjct: 79 SEKRPI 84 >2QA2-A nrPDB Length = 499 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 17/33 (51%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 V+VVGAG G+ LAG G + ++ + Sbjct: 14 SVIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQ 46 >3K6J-A nrPDB Length = 460 Score = 30.6 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 24/55 (43%), Gaps = 4/55 (7%) Query: 177 NIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGET 231 ++P + + + V ++G G +G +A F G ET LV+R E Sbjct: 38 SLPNDRGDHTNSEAYDVN----SVAIIGGGTMGKAMAICFGLAGIETFLVVRNEQ 88 >4G65-A nrPDB Length = 461 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 23/113 (20%), Positives = 43/113 (38%), Gaps = 4/113 (3%) Query: 192 RLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKE 251 RLE+ +++++VG G IG LA L+ R K E ++NTI Sbjct: 230 RLEKPYRRIMIVGGGNIGASLAKRLEQT-YSVKLIERNLQRAEKLSEELENTIVFCGDAA 288 Query: 252 GINVHKLSKIVKVE---KNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGM 301 + I +V+ D+ I +++ I R +++ + Sbjct: 289 DQELLTEENIDQVDVFIALTNEDETNIMSAMLAKRMGAKKVMVLIQRGAYVDL 341 >2BS2-A nrPDB Length = 660 Score = 30.6 bits (68), Expect = 1.6, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLV 52 ++ D LVIGGG G+ +A G T+++ Sbjct: 1 MKVQYCDSLVIGGGLAGLRAAVATQQKGLSTIVL 34 >6MO6-A nrPDB Length = 414 Score = 30.6 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 13/117 (11%), Positives = 37/117 (31%), Gaps = 9/117 (7%) Query: 241 QNTITDHYVKEGINVHKLSKIVKVEKNVETDKLK-IHMNDSKSIDDVDELIWTIGRKSHL 299 + + + + + V+ +++V + + + + + + L T Sbjct: 203 ADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVT---PPMS 259 Query: 300 GMGSENVGIKLNSHDQIIADEY--QNTNVPNIYSLGDVVGKVEL---TPVAIAAGRK 351 ++ + D+ Q+ PN++ +GD VA +G Sbjct: 260 PPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLPTSKTAAAVAAQSGIL 316 >3HG7-A nrPDB Length = 324 Score = 30.6 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 18/126 (14%), Positives = 42/126 (33%), Gaps = 7/126 (5%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 + ++++G G IG +A G + V R FD+ Q + + + Sbjct: 141 RTLLILGTGSIGQHIAHTGKHFGMKVLGVSRSGRERAGFDQVYQLPALNKMLAQA----- 195 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHDQII 317 IV V + + +++ +GR + + G ++ + Sbjct: 196 -DVIVSVLPATRETHHLFTASRFEHCKPG-AILFNVGRGNAINEGDLLTALRTGKLGMAV 253 Query: 318 ADEYQN 323 D ++ Sbjct: 254 LDVFEQ 259 >2WTB-A nrPDB Length = 725 Score = 30.6 bits (68), Expect = 1.7, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 34/96 (35%), Gaps = 9/96 (9%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 KKV ++G G +G +A L E L ++ + K ++ K Sbjct: 313 KKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEK 372 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTI 293 K + + K D +S DVD +I + Sbjct: 373 FEKTMSLLKG---------SLDYESFRDVDMVIEAV 399 >4PRK-A nrPDB Length = 336 Score = 30.2 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 42/102 (41%), Gaps = 2/102 (1%) Query: 185 TDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 T+ D E K + ++G G+IG +A +F +G++ + + + + Sbjct: 134 TNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKV--LAYDVIYNPEVEPYLTYAD 191 Query: 245 TDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDV 286 D +KE + + ++K +N+ K M + + + Sbjct: 192 FDTVLKEADIISLHTPLLKSTENMIGKKQFAEMKNDAILINA 233 >4K22-A nrPDB Length = 365 Score = 30.2 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 14/28 (50%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVI 227 V +VG G +G+ +A G G ++ Sbjct: 6 VAIVGGGMVGLAVACGLQGSGLRVAVLE 33 Score = 29.1 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 17/35 (48%) Query: 21 TKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 + D ++GGG G+A A G + ++E + Sbjct: 1 MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >4D3F-A nrPDB Length = 310 Score = 30.2 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 20/47 (42%), Gaps = 3/47 (6%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTI 244 K V V+G G +G +A VF G + R + K D+ + Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSS---KADQLVAKGA 65 >3KKJ-A nrPDB Length = 336 Score = 30.2 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 12/28 (42%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVI 227 + ++G G G+ A G + HL Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFD 32 >1B04-A nrPDB Length = 318 Score = 30.2 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 8/55 (14%), Positives = 20/55 (36%), Gaps = 2/55 (3%) Query: 209 GIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVK 263 EL + + G E +++ R ++D +Q I ++ + + Sbjct: 10 AAELRELLNRYGYEYYVLDRPSVPDAEYDRLMQELIA--IEEQYPELKTSDSPTQ 62 >1VM7-A nrPDB Length = 311 Score = 30.2 bits (67), Expect = 2.2, Method: Composition-based stats. Identities = 39/236 (16%), Positives = 81/236 (34%), Gaps = 51/236 (21%) Query: 135 VFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLE 194 + G+ R + + D T + N I++ G A + + + ++SD Sbjct: 93 ITGYIRVSLPTGRAFIEVDKTGQ----NRIIIFPGANAELKKELIDWNTLSESDILLLQN 148 Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 254 E P + +E A F+G +VI + +E I + D+ Sbjct: 149 EIPFETT--------LECAKRFNG------IVIFDPAPAQGINEEIFQYL-DYLTPN--- 190 Query: 255 VHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIKLNSHD 314 +I + K+ + L + K ++ +G +NV +KL Sbjct: 191 ---EKEIEALSKDFFGEFLTVEKAAEKFLE----------------LGVKNVIVKLGDKG 231 Query: 315 QIIADEYQNTNVP-------NIYSLGDVVGKVELTPVAIAAGRKLSNR-LFGPEKF 362 ++ ++ + + P + + GDV VA++ G+ +FG Sbjct: 232 VLLVNKNEKKHFPTFKVKAVDTTAAGDVFNGA--FAVALSEGKNPEEAVIFGTAAA 285 >6D9T-A nrPDB Length = 400 Score = 29.9 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 28/80 (35%), Gaps = 6/80 (7%) Query: 204 GAGYIGIELAGVFHGLGSETHLV-----IRGETVLRKFD-ECIQNTITDHYVKEGINVHK 257 G+G I EL G E H + R L ++ + ++ Sbjct: 33 GSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVNQYAVFQYPPYDITL 92 Query: 258 LSKIVKVEKNVETDKLKIHM 277 +KI +V K + D L +H Sbjct: 93 STKIAEVIKEYDLDLLHMHY 112 >4ZCC-A nrPDB Length = 336 Score = 29.9 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 7/28 (25%), Positives = 12/28 (42%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVI 227 + ++G G G+ A G + HL Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFD 32 >3SM8-A nrPDB Length = 381 Score = 29.9 bits (66), Expect = 2.7, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 21/32 (65%), Gaps = 1/32 (3%) Query: 25 DYLVIGGGSGGVASARRAASYGAKTLLVEAKA 56 DYLVIG G G ++ +++G + +++E +A Sbjct: 11 DYLVIGAGIAGASTGYWLSAHG-RVVVLEREA 41 >3RP7-A nrPDB Length = 407 Score = 29.9 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 15/28 (53%) Query: 27 LVIGGGSGGVASARRAASYGAKTLLVEA 54 +VIG G GG+++A G + EA Sbjct: 27 IVIGAGIGGLSAAVALKQSGIDCDVYEA 54 >3I83-A nrPDB Length = 320 Score = 29.9 bits (66), Expect = 2.8, Method: Composition-based stats. Identities = 17/122 (13%), Positives = 38/122 (31%), Gaps = 23/122 (18%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 ++V+G G IG + G +V R + + +GI + + Sbjct: 5 ILVIGTGAIGSFYGALLAKTGHCVSVVSRSD--------------YETVKAKGIRIRSAT 50 Query: 260 ------KIVKVEKNVE--TDKLKIHMNDSKSIDDVDEL-IWTIGRKSHLGMGSENVGIKL 310 + V ++ K + K ++ D + + G+ + GI + Sbjct: 51 LGDYTFRPAAVVRSAAELETKPDCTLLCIKVVEGADRVGLLRDAVAPDTGIVLISNGIDI 110 Query: 311 NS 312 Sbjct: 111 EP 112 >4Z8X-A nrPDB Length = 497 Score = 29.9 bits (66), Expect = 2.9, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 26/61 (42%) Query: 219 LGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMN 278 LG T V +LR+ DE ++ IT+ Y K V + + +K +K I Sbjct: 393 LGGMTTAVDTSPDLLREIDEEVRRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCE 452 Query: 279 D 279 + Sbjct: 453 E 453 >3L6D-A nrPDB Length = 306 Score = 29.9 bits (66), Expect = 3.0, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%) Query: 17 MSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLL 51 +S + +D VIG G+ G A+ G + + Sbjct: 3 LSDESFEFDVSVIGLGAMGTIMAQVLLKQGKRVAI 37 >3FPZ-A nrPDB Length = 326 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 21/38 (55%), Gaps = 3/38 (7%) Query: 25 DYLVIGGGSGGVASARRAASY--GAKTLLVEAK-ALGG 59 D +++G GS G+++A A K ++E+ A GG Sbjct: 67 DVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGG 104 >5TUM-A nrPDB Length = 410 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKAL---GGTCVNV 64 +K+ LVIG G G A +G +L+E A GG ++V Sbjct: 21 MMSKNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDV 69 >1MV8-A nrPDB Length = 436 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 38/110 (34%), Gaps = 20/110 (18%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGET---VLRKFDECIQNTITDHYVKEGINV 255 ++ + G GY+G AG G E V T ++ + I + +++G Sbjct: 2 RISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQG--- 58 Query: 256 HKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIGRKS--HLGMGS 303 +T +L + K++ D D +G S + + Sbjct: 59 ------------RQTGRLSGTTDFKKAVLDSDVSFICVGTPSKKNGDLDL 96 >4HA6-A nrPDB Length = 508 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 12/33 (36%), Positives = 21/33 (63%), Gaps = 1/33 (3%) Query: 25 DYLVIGGGSGG-VASARRAASYGAKTLLVEAKA 56 D +++GGGS G + +AR + ++ LL+EA Sbjct: 3 DIVIVGGGSAGSLLAARLSEDPDSRVLLIEAGE 35 >1VRQ-A nrPDB Length = 964 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 48/315 (15%), Positives = 91/315 (28%), Gaps = 62/315 (19%) Query: 23 HYDYLVIGGGSGGVASARRAASYGAKTLLV-EAKALGGTCVNVGCVPKKVMWYASDLATR 81 H D LV+G G G+A+AR A+ GA+ +L+ E GGT Sbjct: 127 HTDVLVVGAGPAGLAAAREASRSGARVMLLDERPEAGGT--------------------- 165 Query: 82 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 141 + A+ Q +D E + H + + + Sbjct: 166 LREASG---EQIDGIDAAQWIDAVTEELAAAEETTHLQRTTVFGSYDANYILAAQRRTVH 222 Query: 142 NKDGNVEVQKRDNTTEVYSANHILVATGG--KAIF--PENIPGFELGTDSDGFFRLEEQP 197 + + R+ A +++AT + I + PG L + Sbjct: 223 LDGPSGQGVSRERIWH-IRAKQVVLATAAHERPIVFENNDRPGIMLAGSVRSYLN----- 276 Query: 198 KKVVVVGAGYIGIE--------LAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYV 249 + V I + L G ++ + + + + + Sbjct: 277 -RFGVRAGSKIAVATTNDSVYPLVSELAASGGVVAVIDARQNISAAAAQAVTD------- 328 Query: 250 KEGINVHKLSKIVKVEKNVETDKLKIHMN--------DSKSIDDVDELIWTIGRKSHLGM 301 G+ V S + E + + + + + D L + G + + Sbjct: 329 --GVTVLTGSVVANTEADASGELSAVLVATLDEQRNLGEAQRFEADVLAVSGGFNPVVHL 386 Query: 302 GSENVGIKLNSHDQI 316 S+ G KLN I Sbjct: 387 HSQRQG-KLNWDTSI 400 >3LOV-A nrPDB Length = 475 Score = 29.5 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 20/177 (11%), Positives = 50/177 (28%), Gaps = 48/177 (27%) Query: 198 KKVVVVGAGYIGIELAGVFHGL--GSETHLVIRGETVL--------------RKFDECIQ 241 K++V+VG G G+ A L+ GE + R D + Sbjct: 5 KRLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFTIERGPDSYVA 64 Query: 242 NT-----------ITDHYVKE-----------GINVHKLSKIVKVEKNVETDKLKIHMND 279 + + V+ G++ ++ + +++ + + + Sbjct: 65 RKHILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLDLFRQTTLLTE 124 Query: 280 SKSIDDVDELIWTIGRKSHLGMGSENVGIKLNS-----HDQIIADEYQNTNVPNIYS 331 + + D L+ + I L + ++ + IY+ Sbjct: 125 EEKQEVADLLL-----HPSDSLRIPEQDIPLGEYLRPRLGDALVEKLIEPLLSGIYA 176 >4Z44-A nrPDB Length = 554 Score = 29.5 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 26 YLVIGGGSGGVASA---RRAASYGAKTLLVEAKAL 57 +++GGG+ G +A RA A L+E+ A+ Sbjct: 24 IVIVGGGTAGWMAASYLVRALQQQANITLIESAAI 58 >1H5Y-A nrPDB Length = 253 Score = 29.5 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 11/93 (11%), Positives = 32/93 (34%), Gaps = 13/93 (13%) Query: 201 VVVGAGYIGIELAGVFHGLGSE-THLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLS 259 V+VG G +E A G++ + + + + + + S Sbjct: 80 VLVGGGVRSLEDATTLFRAGADKVSVNTAAVR-----NPQLVALLAREFGSQ-------S 127 Query: 260 KIVKVEKNVETDKLKIHMNDSKSIDDVDELIWT 292 +V ++ + ++++ + +D + W Sbjct: 128 TVVAIDAKWNGEYYEVYVKGGREATGLDAVKWA 160 >4JA9-A nrPDB Length = 488 Score = 29.5 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 9/71 (12%) Query: 308 IKLNSHDQIIAD----EYQNTNVPNIYSLGDVVGKVELTPVAIAA--GRKLSNRLFGPEK 361 I+LN + I Y T Y+LGD +EL I R SN G K Sbjct: 44 IELNPSNAIYYGNRSLAYLRTECYG-YALGDATRAIELDKKYIKGYYRRAASNMALG--K 100 Query: 362 FRNDKLDYENV 372 FR DYE V Sbjct: 101 FRAALRDYETV 111 >1QU3-A nrPDB Length = 917 Score = 29.5 bits (65), Expect = 3.6, Method: Composition-based stats. Identities = 16/130 (12%), Positives = 46/130 (35%), Gaps = 11/130 (8%) Query: 207 YIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEK 266 +I +EL+ + G + + + ++ +R+ + + I K + + Sbjct: 711 FINVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSH 770 Query: 267 NVETDKLKIHMNDSKSIDDVDELIW-----------TIGRKSHLGMGSENVGIKLNSHDQ 315 + +H+ D + +VD+ + + R + +G L + Sbjct: 771 TPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVT 830 Query: 316 IIADEYQNTN 325 I +++ N + Sbjct: 831 IASNDKFNAS 840 >2DI4-A nrPDB Length = 238 Score = 29.5 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 26/61 (42%) Query: 219 LGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMN 278 LG T V +LR+ DE ++ IT+ Y K V + + +K +K I Sbjct: 134 LGGMTTAVDTSPDLLREIDEEVKRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCE 193 Query: 279 D 279 + Sbjct: 194 E 194 >6F73-A nrPDB Length = 574 Score = 29.1 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 17/39 (43%), Gaps = 7/39 (17%) Query: 29 IGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCV 67 +G G G + A S G + + GGTC VG V Sbjct: 197 LGAGVEGFEAYAMANSTGHRIV-------GGTCPTVGIV 228 >1A17-A nrPDB Length = 166 Score = 29.1 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 9/71 (12%) Query: 308 IKLNSHDQIIAD----EYQNTNVPNIYSLGDVVGKVELTPVAIAA--GRKLSNRLFGPEK 361 I+LN + I Y T Y+LGD +EL I R SN G K Sbjct: 40 IELNPSNAIYYGNRSLAYLRTECYG-YALGDATRAIELDKKYIKGYYRRAASNMALG--K 96 Query: 362 FRNDKLDYENV 372 FR DYE V Sbjct: 97 FRAALRDYETV 107 >3TR4-A nrPDB Length = 178 Score = 29.1 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 29/74 (39%), Gaps = 10/74 (13%) Query: 312 SHDQIIADEYQNTN---------VPNIYSL-GDVVGKVELTPVAIAAGRKLSNRLFGPEK 361 + D + T+ VP+ + GD + + LTPV + G + R G K Sbjct: 37 ELGFLTVDRFMPTSMRYPCNYGFVPSTLAQDGDPLDVLVLTPVPVQPGVLMRVRALGIMK 96 Query: 362 FRNDKLDYENVPSV 375 ++ + V +V Sbjct: 97 MEDEAGEDSKVLAV 110 >4Y0E-A nrPDB Length = 338 Score = 29.1 bits (64), Expect = 4.3, Method: Composition-based stats. Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 7 QTFRSLQIRTMSTNTKHYDYLVIGGGSGGVASARRAASY 45 + RSL +T+T YDY G SGGV++ RRAA Y Sbjct: 166 KPLRSLVDDLWATHTNLYDYASSGA-SGGVSAERRAAYY 203 >4X4J-A nrPDB Length = 507 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 15/31 (48%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLVIRGE 230 VV+ GAG G+ LAG G ++ R Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIGVVVLERLP 55 >4GL2-A nrPDB Length = 699 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 281 KSIDDVDELIWTIGRKSHLGMGSEN---VGIKLNSHDQIIADEYQNTNVPNIY 330 + + D +I T + + EN G++L+ II DE +TN +Y Sbjct: 102 EVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVY 154 >3B6E-A nrPDB Length = 216 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 281 KSIDDVDELIWTIGRKSHLGMGSEN---VGIKLNSHDQIIADEYQNTNVPNIY 330 + + D +I T + + EN G++L+ II DE +TN +Y Sbjct: 128 EVVKSCDIIISTAQILENSLLNLENGEDAGVQLSDFSLIIIDECHHTNKEAVY 180 >1PJ5-A nrPDB Length = 830 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 19/38 (50%), Gaps = 1/38 (2%) Query: 199 KVVVVGAGYIGIELAGVFHGLG-SETHLVIRGETVLRK 235 ++V++GAG +G LA G + ++ +G + Sbjct: 6 RIVIIGAGIVGTNLADELVTRGWNNITVLDQGPLNMPG 43 >3CUK-A nrPDB Length = 347 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 9/39 (23%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD 237 +VVV+GAG IG+ A H R +VL+ D Sbjct: 2 RVVVIGAGVIGLSTALCIH---------ERYHSVLQPLD 31 >1VE9-A nrPDB Length = 347 Score = 29.1 bits (64), Expect = 4.4, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 9/39 (23%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFD 237 +VVV+GAG IG+ A H R +VL+ D Sbjct: 2 RVVVIGAGVIGLSTALCIH---------ERYHSVLQPLD 31 >1XFD-A nrPDB Length = 723 Score = 29.1 bits (64), Expect = 4.5, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 32/56 (57%), Gaps = 5/56 (8%) Query: 424 YKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEEL 479 +K+ + +E+ +GLH + + + E+ + VA ++ A + + IHPT+ E++ Sbjct: 619 FKLYASAFSERYLGLHGLDNRAYEMTK---VAHRVSALEEQ--QFLIIHPTADEKI 669 >3K8D-A nrPDB Length = 264 Score = 29.1 bits (64), Expect = 5.0, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 16/43 (37%), Gaps = 7/43 (16%) Query: 334 DVVGKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 376 D+ GK + V A + R+ D+E+V + Sbjct: 39 DINGKPMIVHVLERARESGAERII-------VATDHEDVARAV 74 >3X2F-A nrPDB Length = 411 Score = 28.7 bits (63), Expect = 5.5, Method: Composition-based stats. Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 26 YLVIGGGSGGVASARRAASYGAKTLLVE 53 +V G G G A RAA GA+ ++ E Sbjct: 200 VVVAGYGWCGRGIALRAAGLGARVIVTE 227 >2EW2-A nrPDB Length = 316 Score = 28.7 bits (63), Expect = 5.6, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 16/29 (55%) Query: 199 KVVVVGAGYIGIELAGVFHGLGSETHLVI 227 K+ + GAG +G L + H G++ L+ Sbjct: 5 KIAIAGAGAMGSRLGIMLHQGGNDVTLID 33 >5Y77-A nrPDB Length = 473 Score = 28.7 bits (63), Expect = 5.7, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%), Gaps = 1/58 (1%) Query: 195 EQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG 252 + ++V ++GAG G +A + G + +L R R +I + G Sbjct: 6 DNARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDP-RIETGARGRSINLALAERG 62 >6OKK-C nrPDB Length = 263 Score = 28.7 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 20/54 (37%), Gaps = 2/54 (3%) Query: 7 QTFRSLQI--RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALG 58 +T+ LQ+ R + + D +V+ G + + A Y + G Sbjct: 52 KTYEKLQLAARIIVAISNPADVVVVSARPFGSRAVLKFAQYTGAQAIAGRWTPG 105 >3JBO-C nrPDB Length = 195 Score = 28.7 bits (63), Expect = 5.9, Method: Composition-based stats. Identities = 10/54 (18%), Positives = 20/54 (37%), Gaps = 2/54 (3%) Query: 7 QTFRSLQI--RTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALG 58 +T+ LQ+ R + + D +V+ G + + A Y + G Sbjct: 43 KTYEKLQLAARIIVAISNPADVVVVSARPFGSRAVLKFAQYTGAQAIAGRWTPG 96 >1UIR-A nrPDB Length = 314 Score = 28.7 bits (63), Expect = 6.1, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 20/55 (36%), Gaps = 8/55 (14%) Query: 196 QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVK 250 +PK+V++VG G E + + + V+ D + H + Sbjct: 77 EPKRVLIVGGG----E-GATLREVLKHPTV---EKAVMVDIDGELVEVAKRHMPE 123 >4EIQ-A nrPDB Length = 549 Score = 28.7 bits (63), Expect = 6.2, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 17/37 (45%) Query: 19 TNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAK 55 D L++GGG G+A A A L+V+A Sbjct: 22 NAPIETDVLILGGGPVGMALALDLAHRQVGHLVVDAG 58 >5ZYN-B nrPDB Length = 471 Score = 28.7 bits (63), Expect = 6.5, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 20/37 (54%), Gaps = 2/37 (5%) Query: 26 YLVIGGGSGGVASARRA-ASYGAKTLLVEAKA-LGGT 60 +VIG G G+ ++ R + Y +L++ A +GG Sbjct: 7 VVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGGN 43 >2B76-A nrPDB Length = 602 Score = 28.3 bits (62), Expect = 6.7, Method: Composition-based stats. Identities = 4/22 (18%), Positives = 11/22 (50%) Query: 314 DQIIADEYQNTNVPNIYSLGDV 335 I D+ T + ++++G+ Sbjct: 360 GGIETDQNCETRIKGLFAVGEC 381 >3F52-A nrPDB Length = 117 Score = 28.3 bits (62), Expect = 7.2, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 439 HIVGDSSAEILQGFGVAIKMGATKADFDNCVA-IHP 473 H +G S A++L ++ + A + D + HP Sbjct: 78 HALGASVADVLIEAAGSMALQAAQEDLARVLEWSHP 113 >3MOG-A nrPDB Length = 483 Score = 28.3 bits (62), Expect = 7.2, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 37/100 (37%), Gaps = 19/100 (19%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVI-RGETVLRKFDECIQNTITDHYVKEGINVH 256 + V V+G+G +G +A V G + L E + R D GI+ Sbjct: 6 QTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAID--------------GIHAR 51 Query: 257 KLSKIVK----VEKNVETDKLKIHMNDSKSIDDVDELIWT 292 S++ + E T K I + D ++ D +I Sbjct: 52 LNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEA 91 >4M1Q-A nrPDB Length = 339 Score = 28.3 bits (62), Expect = 7.3, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 54/159 (33%), Gaps = 33/159 (20%) Query: 180 GFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDEC 239 G +LGT++ F + + +VV++G G +G A F + E VL D Sbjct: 10 GVDLGTENLYFQSMNTKTSRVVIIGTGAVGSSYA--FSMINQNVT----DEMVL--IDLD 61 Query: 240 IQNTITDHYV-KEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDVDELIWTIG--RK 296 + T D GI +K+ D D ++ T G +K Sbjct: 62 KRKTEGDAMDLNHGIPFGAPTKVWA--------------GDYGDCKSADIVVITAGAAQK 107 Query: 297 S---HLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSL 332 L + +N I I D+ + I+ + Sbjct: 108 PGETRLDLVEKNANIFKG-----IVDQVMGSGFNGIFII 141 >2RGJ-A nrPDB Length = 402 Score = 28.3 bits (62), Expect = 7.4, Method: Composition-based stats. Identities = 31/163 (19%), Positives = 57/163 (34%), Gaps = 20/163 (12%) Query: 25 DYLVIGGGSGGVASARRAASYGA-KTLLVEAK---ALGGTCVNV-----------GCVPK 69 D L+ G G GG++ A G K L+E+ G +N+ G P Sbjct: 6 DILIAGAGIGGLSCALALHQAGIGKVTLLESSSEIRPLGVGINIQPAAVEALAELGLGP- 64 Query: 70 KVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEK 129 + + + + ++ G +P++ R L ++ L + Sbjct: 65 -ALAATAIPTHELRYIDQSGATVWSEPRGVEAGNAYPQYSIHRGELQMILLAAVRERLGQ 123 Query: 130 EKVDVVFGWARFNK-DGNVEVQKRDNTT--EVYSANHILVATG 169 + V G R + DG V + RD + A+ ++ A G Sbjct: 124 QAVRTGLGVERIEERDGRVLIGARDGHGKPQALGADVLVGADG 166 >2A9F-A nrPDB Length = 398 Score = 28.3 bits (62), Expect = 7.6, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Query: 14 IRTMSTNTKHYDYLVIGGGSGGVASARRAASYGA-KTLLVEAKAL 57 ++ + + +V GGGS G++ R+ + GA K +V+ + Sbjct: 179 LKLLKKSLDEVSIVVNGGGSAGLSITRKLLAAGATKVTVVDKFGI 223 >2ZJ1-A nrPDB Length = 495 Score = 28.3 bits (62), Expect = 7.7, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 27/87 (31%), Gaps = 18/87 (20%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK 257 KKV++ G G +G A G G+ + N + Sbjct: 276 KKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPI----------NALQAMME-------- 317 Query: 258 LSKIVKVEKNVETDKLKIHMNDSKSID 284 +V VE+ + + + +K I Sbjct: 318 GFDVVTVEEAIGDADIVVTATGNKDII 344 >2YQ5-A nrPDB Length = 343 Score = 28.3 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 38/86 (44%), Gaps = 7/86 (8%) Query: 187 SDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITD 246 S+ + L V ++G G+IG +A +F +G++ + +F+ + T D Sbjct: 143 SNEIYNL-----TVGLIGVGHIGSAVAEIFSAMGAKV--IAYDVAYNPEFEPFLTYTDFD 195 Query: 247 HYVKEGINVHKLSKIVKVEKNVETDK 272 +KE V + + +N+ +K Sbjct: 196 TVLKEADIVSLHTPLFPSTENMIGEK 221 >3JSK-A nrPDB Length = 344 Score = 28.3 bits (62), Expect = 7.8, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 23 HYDYLVIGGGSGGVASARRAASY--GAKTLLVEAK-ALGG 59 D +++G GS G+++A ++ + +VEA A GG Sbjct: 79 ETDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGG 118 >3I6D-A nrPDB Length = 470 Score = 28.3 bits (62), Expect = 7.9, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 9/50 (18%) Query: 17 MSTNTKHYDYLVIGGGSGGVASA------RRAASYGAKTLLVEA-KALGG 59 MS KH ++IGGG G+A+A + + + LVEA +GG Sbjct: 1 MSDGKKH--VVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGG 48 >2QK4-A nrPDB Length = 452 Score = 28.3 bits (62), Expect = 8.6, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 15/37 (40%), Gaps = 1/37 (2%) Query: 26 YLVIGGGSGGVASARRAAS-YGAKTLLVEAKALGGTC 61 L+IG G A + A + K +LV G C Sbjct: 27 VLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTAC 63 >1QP8-A nrPDB Length = 303 Score = 27.9 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 11/54 (20%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 198 KKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLR-KFDECIQNTITDHYVK 250 +KV V+G G IG + + LG++ R +F ++ + + Sbjct: 125 EKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPKEGPWRFTNSLEEALREARAA 178 >5Z23-C nrPDB Length = 167 Score = 27.9 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 16/96 (16%), Positives = 34/96 (35%), Gaps = 5/96 (5%) Query: 210 IELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEG-----INVHKLSKIVKV 264 +ELAG +T ++ R + + DE + + + +G I L K + Sbjct: 67 LELAGNAARDNKKTRIIPRHLQLAIRNDEEMNKLLGRVTIAQGGVLPNIQAVLLPKKTES 126 Query: 265 EKNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLG 300 + +L I ++ + I G ++ Sbjct: 127 HHKAKGKQLAIRNDEEMNKLLGRVTIAQGGVLPNIQ 162 >2CUL-A nrPDB Length = 232 Score = 27.9 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 10/27 (37%), Positives = 14/27 (51%) Query: 200 VVVVGAGYIGIELAGVFHGLGSETHLV 226 V++VGAG+ G E A G L+ Sbjct: 6 VLIVGAGFSGAETAFWLAQKGVRVGLL 32 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.151 0.430 Lambda K H 0.267 0.0464 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,628,011 Number of Sequences: 36641 Number of extensions: 984776 Number of successful extensions: 5466 Number of sequences better than 10.0: 404 Number of HSP's better than 10.0 without gapping: 406 Number of HSP's successfully gapped in prelim test: 166 Number of HSP's that attempted gapping in prelim test: 3691 Number of HSP's gapped (non-prelim): 982 length of query: 483 length of database: 10,336,785 effective HSP length: 101 effective length of query: 382 effective length of database: 6,636,044 effective search space: 2534968808 effective search space used: 2534968808 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (27.9 bits)